LOCUS       DADQDV010000001        91988 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.001, whole genome shotgun sequence.
ACCESSION   DADQDV010000001 DADQDV010000000
VERSION     DADQDV010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 91988)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 91988)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..91988
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.001"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..420
                     /locus_tag="J8S10_000001"
     CDS             <1..420
                     /locus_tag="J8S10_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HAZ9628621.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQPVVQETVQTEK
                     QAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQLDSSYL
                     NGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            complement(504..1226)
                     /locus_tag="J8S10_000002"
     CDS             complement(504..1226)
                     /locus_tag="J8S10_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HAZ9628622.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(1216..1953)
                     /locus_tag="J8S10_000003"
     CDS             complement(1216..1953)
                     /locus_tag="J8S10_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9628623.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            complement(1965..2957)
                     /locus_tag="J8S10_000004"
     CDS             complement(1965..2957)
                     /locus_tag="J8S10_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAZ9628624.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            complement(2972..3715)
                     /locus_tag="J8S10_000005"
     CDS             complement(2972..3715)
                     /locus_tag="J8S10_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9628625.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     regulatory      complement(3789..3893)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(3956..5278)
                     /locus_tag="J8S10_000006"
     CDS             complement(3956..5278)
                     /locus_tag="J8S10_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAZ9628626.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     gene            complement(5265..6230)
                     /locus_tag="J8S10_000007"
     CDS             complement(5265..6230)
                     /locus_tag="J8S10_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9628627.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            complement(6227..7765)
                     /locus_tag="J8S10_000008"
     CDS             complement(6227..7765)
                     /locus_tag="J8S10_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HAZ9628628.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            complement(8181..8468)
                     /locus_tag="J8S10_000009"
     CDS             complement(8181..8468)
                     /locus_tag="J8S10_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9628629.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            8602..9270
                     /locus_tag="J8S10_000010"
     CDS             8602..9270
                     /locus_tag="J8S10_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAZ9628630.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            complement(9561..10301)
                     /locus_tag="J8S10_000011"
     CDS             complement(9561..10301)
                     /locus_tag="J8S10_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9628631.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(10431..11378)
                     /locus_tag="J8S10_000012"
     CDS             complement(10431..11378)
                     /locus_tag="J8S10_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAZ9628632.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            complement(11507..12271)
                     /locus_tag="J8S10_000013"
     CDS             complement(11507..12271)
                     /locus_tag="J8S10_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAZ9628633.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            complement(12275..12664)
                     /locus_tag="J8S10_000014"
     CDS             complement(12275..12664)
                     /locus_tag="J8S10_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9628634.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            12799..13341
                     /locus_tag="J8S10_000015"
     CDS             12799..13341
                     /locus_tag="J8S10_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HAZ9628635.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            13489..14121
                     /locus_tag="J8S10_000016"
     CDS             13489..14121
                     /locus_tag="J8S10_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9628636.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(14255..14380)
                     /locus_tag="J8S10_000017"
     CDS             complement(14255..14380)
                     /locus_tag="J8S10_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAZ9628637.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(14514..15407)
                     /locus_tag="J8S10_000018"
     CDS             complement(14514..15407)
                     /locus_tag="J8S10_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HAZ9628638.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEIAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            complement(15589..16515)
                     /locus_tag="J8S10_000019"
     CDS             complement(15589..16515)
                     /locus_tag="J8S10_000019"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HAZ9628639.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            complement(16600..17361)
                     /gene="pflA"
                     /locus_tag="J8S10_000020"
     CDS             complement(16600..17361)
                     /gene="pflA"
                     /locus_tag="J8S10_000020"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HAZ9628640.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            complement(17605..19836)
                     /gene="pflB"
                     /locus_tag="J8S10_000021"
     CDS             complement(17605..19836)
                     /gene="pflB"
                     /locus_tag="J8S10_000021"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HAZ9628641.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            complement(20113..22563)
                     /gene="parC"
                     /locus_tag="J8S10_000022"
     CDS             complement(20113..22563)
                     /gene="parC"
                     /locus_tag="J8S10_000022"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HAZ9628642.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            complement(22575..24620)
                     /gene="parE"
                     /locus_tag="J8S10_000023"
     CDS             complement(22575..24620)
                     /gene="parE"
                     /locus_tag="J8S10_000023"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HAZ9628643.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            complement(24786..25220)
                     /locus_tag="J8S10_000024"
     CDS             complement(24786..25220)
                     /locus_tag="J8S10_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HAZ9628644.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            25347..25985
                     /gene="plsY"
                     /locus_tag="J8S10_000025"
     CDS             25347..25985
                     /gene="plsY"
                     /locus_tag="J8S10_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HAZ9628645.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            complement(26117..26992)
                     /locus_tag="J8S10_000026"
     CDS             complement(26117..26992)
                     /locus_tag="J8S10_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HAZ9628646.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(27074..27865)
                     /gene="codY"
                     /locus_tag="J8S10_000027"
     CDS             complement(27074..27865)
                     /gene="codY"
                     /locus_tag="J8S10_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HAZ9628647.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            complement(27883..29283)
                     /gene="hslU"
                     /locus_tag="J8S10_000028"
     CDS             complement(27883..29283)
                     /gene="hslU"
                     /locus_tag="J8S10_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HAZ9628648.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            complement(29297..29845)
                     /gene="hslV"
                     /locus_tag="J8S10_000029"
     CDS             complement(29297..29845)
                     /gene="hslV"
                     /locus_tag="J8S10_000029"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HAZ9628649.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            complement(29882..30787)
                     /gene="xerC"
                     /locus_tag="J8S10_000030"
     CDS             complement(29882..30787)
                     /gene="xerC"
                     /locus_tag="J8S10_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HAZ9628650.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(30985..32361)
                     /gene="trmFO"
                     /locus_tag="J8S10_000031"
     CDS             complement(30985..32361)
                     /gene="trmFO"
                     /locus_tag="J8S10_000031"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HAZ9628651.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(32330..34408)
                     /gene="topA"
                     /locus_tag="J8S10_000032"
     CDS             complement(32330..34408)
                     /gene="topA"
                     /locus_tag="J8S10_000032"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HAZ9628652.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(34530..35387)
                     /gene="dprA"
                     /locus_tag="J8S10_000033"
     CDS             complement(34530..35387)
                     /gene="dprA"
                     /locus_tag="J8S10_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HAZ9628653.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(35443..36210)
                     /locus_tag="J8S10_000034"
     CDS             complement(35443..36210)
                     /locus_tag="J8S10_000034"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HAZ9628654.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(36203..37063)
                     /gene="ylqF"
                     /locus_tag="J8S10_000035"
     CDS             complement(36203..37063)
                     /gene="ylqF"
                     /locus_tag="J8S10_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HAZ9628655.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            37323..37721
                     /locus_tag="J8S10_000036"
     CDS             37323..37721
                     /locus_tag="J8S10_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAZ9628656.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            37958..38500
                     /locus_tag="J8S10_000037"
     CDS             37958..38500
                     /locus_tag="J8S10_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HAZ9628657.1"
                     /translation="MNTLIAKDVFRLPEMNARLLSTSALLLALDVILYKIAIGPAYFQ
                     ITFGFLSMALMGYLYGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLF
                     LYHKKINLPSVIAAQLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQI
                     MVVYSFIKTLEARKVFKRAV"
     gene            complement(38583..39134)
                     /gene="lepB"
                     /locus_tag="J8S10_000038"
     CDS             complement(38583..39134)
                     /gene="lepB"
                     /locus_tag="J8S10_000038"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAZ9628658.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(39286..39513)
                     /locus_tag="J8S10_000039"
     CDS             complement(39286..39513)
                     /locus_tag="J8S10_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HAZ9628659.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            complement(39510..40028)
                     /gene="msrA"
                     /locus_tag="J8S10_000040"
     CDS             complement(39510..40028)
                     /gene="msrA"
                     /locus_tag="J8S10_000040"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAZ9628660.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            complement(40048..40761)
                     /locus_tag="J8S10_000041"
     CDS             complement(40048..40761)
                     /locus_tag="J8S10_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HAZ9628661.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            complement(40764..41660)
                     /locus_tag="J8S10_000042"
     CDS             complement(40764..41660)
                     /locus_tag="J8S10_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAZ9628662.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            complement(41818..42660)
                     /locus_tag="J8S10_000043"
     CDS             complement(41818..42660)
                     /locus_tag="J8S10_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAZ9628663.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            42792..43445
                     /locus_tag="J8S10_000044"
     CDS             42792..43445
                     /locus_tag="J8S10_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HAZ9628664.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            complement(43508..44035)
                     /locus_tag="J8S10_000045"
     CDS             complement(43508..44035)
                     /locus_tag="J8S10_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAZ9628665.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(44055..45002)
                     /locus_tag="J8S10_000046"
     CDS             complement(44055..45002)
                     /locus_tag="J8S10_000046"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HAZ9628666.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            complement(45014..46900)
                     /locus_tag="J8S10_000047"
     CDS             complement(45014..46900)
                     /locus_tag="J8S10_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAZ9628667.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            complement(47060..49138)
                     /locus_tag="J8S10_000048"
     CDS             complement(47060..49138)
                     /locus_tag="J8S10_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HAZ9628668.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            complement(49151..49426)
                     /locus_tag="J8S10_000049"
     CDS             complement(49151..49426)
                     /locus_tag="J8S10_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9628669.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            complement(49788..50243)
                     /locus_tag="J8S10_000050"
     CDS             complement(49788..50243)
                     /locus_tag="J8S10_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9628670.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(50397..51605)
                     /locus_tag="J8S10_000051"
     CDS             complement(50397..51605)
                     /locus_tag="J8S10_000051"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HAZ9628671.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(51717..52049)
                     /locus_tag="J8S10_000052"
     CDS             complement(51717..52049)
                     /locus_tag="J8S10_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HAZ9628672.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            52197..53072
                     /locus_tag="J8S10_000053"
     CDS             52197..53072
                     /locus_tag="J8S10_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAZ9628673.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(53154..53735)
                     /locus_tag="J8S10_000054"
     CDS             complement(53154..53735)
                     /locus_tag="J8S10_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IDEAL domain-containing protein"
                     /protein_id="HAZ9628674.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(53741..55000)
                     /locus_tag="J8S10_000055"
     CDS             complement(53741..55000)
                     /locus_tag="J8S10_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HAZ9628675.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(55002..56048)
                     /locus_tag="J8S10_000056"
     CDS             complement(55002..56048)
                     /locus_tag="J8S10_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9628676.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            complement(56283..56558)
                     /locus_tag="J8S10_000057"
     CDS             complement(56283..56558)
                     /locus_tag="J8S10_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008214712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HAZ9628677.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(56801..58111)
                     /locus_tag="J8S10_000058"
     CDS             complement(56801..58111)
                     /locus_tag="J8S10_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HAZ9628678.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(58293..59522)
                     /gene="rpsA"
                     /locus_tag="J8S10_000059"
     CDS             complement(58293..59522)
                     /gene="rpsA"
                     /locus_tag="J8S10_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HAZ9628679.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(59657..60337)
                     /locus_tag="J8S10_000060"
     CDS             complement(59657..60337)
                     /locus_tag="J8S10_000060"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HAZ9628680.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(60386..61021)
                     /locus_tag="J8S10_000061"
     CDS             complement(60386..61021)
                     /locus_tag="J8S10_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAZ9628681.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(61087..62490)
                     /locus_tag="J8S10_000062"
     CDS             complement(61087..62490)
                     /locus_tag="J8S10_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HAZ9628682.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWGTILLNLFKKNMEH"
     gene            complement(62477..63508)
                     /locus_tag="J8S10_000063"
     CDS             complement(62477..63508)
                     /locus_tag="J8S10_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9628683.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            63539..63760
                     /locus_tag="J8S10_000064"
     CDS             63539..63760
                     /locus_tag="J8S10_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HAZ9628684.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(63925..64662)
                     /locus_tag="J8S10_000065"
     CDS             complement(63925..64662)
                     /locus_tag="J8S10_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HAZ9628685.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(64815..66155)
                     /locus_tag="J8S10_000066"
     CDS             complement(64815..66155)
                     /locus_tag="J8S10_000066"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HAZ9628686.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(66392..67915)
                     /locus_tag="J8S10_000067"
     CDS             complement(66392..67915)
                     /locus_tag="J8S10_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HAZ9628687.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(68292..68903)
                     /locus_tag="J8S10_000068"
     CDS             complement(68292..68903)
                     /locus_tag="J8S10_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAZ9628688.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(69026..69151)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(69233..69949)
                     /locus_tag="J8S10_000069"
     CDS             complement(69233..69949)
                     /locus_tag="J8S10_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HAZ9628689.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(69955..70524)
                     /gene="scpB"
                     /locus_tag="J8S10_000070"
     CDS             complement(69955..70524)
                     /gene="scpB"
                     /locus_tag="J8S10_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HAZ9628690.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(70508..71305)
                     /locus_tag="J8S10_000071"
     CDS             complement(70508..71305)
                     /locus_tag="J8S10_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HAZ9628691.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(71275..71646)
                     /locus_tag="J8S10_000072"
     CDS             complement(71275..71646)
                     /locus_tag="J8S10_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HAZ9628692.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(71665..72552)
                     /gene="xerD"
                     /locus_tag="J8S10_000073"
     CDS             complement(71665..72552)
                     /gene="xerD"
                     /locus_tag="J8S10_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HAZ9628693.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            complement(72648..73121)
                     /locus_tag="J8S10_000074"
     CDS             complement(72648..73121)
                     /locus_tag="J8S10_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAZ9628694.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            complement(73226..74089)
                     /locus_tag="J8S10_000075"
     CDS             complement(73226..74089)
                     /locus_tag="J8S10_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAZ9628695.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            complement(74285..76384)
                     /locus_tag="J8S10_000076"
     CDS             complement(74285..76384)
                     /locus_tag="J8S10_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HAZ9628696.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            complement(76604..77713)
                     /gene="rpoD"
                     /locus_tag="J8S10_000077"
     CDS             complement(76604..77713)
                     /gene="rpoD"
                     /locus_tag="J8S10_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HAZ9628697.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            complement(77737..79578)
                     /locus_tag="J8S10_000078"
     CDS             complement(77737..79578)
                     /locus_tag="J8S10_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HAZ9628698.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            complement(79760..82153)
                     /locus_tag="J8S10_000079"
     CDS             complement(79760..82153)
                     /locus_tag="J8S10_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAZ9628699.1"
                     /translation="MFLILEHARLKHVIIFESWRKMEKKKMNGLTQQEVVQKMASGQQ
                     NDYQEDASKSTKQIFSDNILTLFNFLNFGIGICLLFVGAYSNMAYLAIIVVNIVIGIY
                     QEIHARNLVRKLSIVSQSEVLVIRDGKEQSISTKELVLGDLVKIGAGEQIPADLQVIS
                     GRAEANEALLTGESDLIVKETGAELLSGSFLTSGSVMAEVIRVGADNYAVRLTSEAKT
                     HKAIRSELVDSIRKVSKFTSFVIIPLGIILFLEALFIRDASIKISVIASAAALLGMLP
                     KGLVLLISIALTTGVTKLAKKRILVQDMYSIETLAHVDTLCLDKTGTITEGKMSIQRV
                     EALHPLYEKAIPEIMGTYLAESSDNNITMRAMRDYFELSNRYDVTNKVAFSSDRKWGA
                     MEFPELGVVYVGAPERLVEEDRLPDSLKTAQANGYRVLMLGIAPNQQLNEEKPAFVEP
                     VALFEIDDPIRKNAQETLAYLHEEGVDLKVISGDNPFTVSNIARRAGLPNYDAYVDLS
                     QITEEMEVREAAHRYTVFGRVSPQQKKLLVNELKESGRTVAMTGDGVNDVLALREADC
                     SIAMAEGDGATRQIANLVLLDSDFTTLPEVLFEGRRVVNNVTKVSGIFFIKTIYSFIL
                     SIICAVTAIGFPFIPIQITLIDLAIEGYPSFFLSFEQDKRKITYRYLPTALINALPNA
                     LLVVVNIIAVYLLGKTFAWGNAETTTLMYYLLIGISCMAVVKACYPFNPLRIFLAVTT
                     IVGIYVAAMLFHGILEVNLGLGESVGYFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            complement(82260..83120)
                     /locus_tag="J8S10_000080"
     CDS             complement(82260..83120)
                     /locus_tag="J8S10_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HAZ9628700.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            complement(83179..83700)
                     /locus_tag="J8S10_000081"
     CDS             complement(83179..83700)
                     /locus_tag="J8S10_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="HAZ9628701.1"
                     /translation="MESYQIEITTAAKNYHMENYENLIKAIILTESKGKGTDLMQSSE
                     SLHGEAEIIDNPADSIDQGVKYLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHG
                     GENTVELAEAYSKDVLSPLLGNEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKM
                     NEKIIETYEKVFK"
     gene            84020..84739
                     /locus_tag="J8S10_000082"
     CDS             84020..84739
                     /locus_tag="J8S10_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAZ9628702.1"
                     /translation="MKKEKKYAKMPDGSEIYYEKSGQGFPLFLLHGNDGSGRFFSEQV
                     PVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEKIDQADFLGFSDGAN
                     LALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVWLLSLFRPSLRKNLL
                     VIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKTIPKASFVLVKEQGH
                     ELARKDPERFNREVLQFLSET"
     gene            84765..87356
                     /gene="mprF"
                     /locus_tag="J8S10_000083"
     CDS             84765..87356
                     /gene="mprF"
                     /locus_tag="J8S10_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HAZ9628703.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKC"
     gene            complement(87544..88731)
                     /gene="tuf"
                     /locus_tag="J8S10_000084"
     CDS             complement(87544..88731)
                     /gene="tuf"
                     /locus_tag="J8S10_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HAZ9628704.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            89099..89455
                     /locus_tag="J8S10_000085"
     CDS             89099..89455
                     /locus_tag="J8S10_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAZ9628705.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            complement(89696..90700)
                     /locus_tag="J8S10_000086"
     CDS             complement(89696..90700)
                     /locus_tag="J8S10_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HAZ9628706.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            90866..91717
                     /locus_tag="J8S10_000087"
     CDS             90866..91717
                     /locus_tag="J8S10_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HAZ9628707.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            91734..91979
                     /locus_tag="J8S10_000088"
     CDS             91734..91979
                     /locus_tag="J8S10_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9628708.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
BASE COUNT        25454 a        19315 c        15783 g        31436 t
ORIGIN      
        1 tactcaggac aacaattaac aatcccaaca gaaggctctg cacaagcagc tgctgaacct
       61 caagcagccg ttcaagaagc accagtccaa gctgaacaac ctgttgtaca agaaacggtt
      121 caaacggaaa aacaagcagc gcctgttgct gaaacacaac ctgctcctgc tgtaacagaa
      181 actgctgcta ctccagcaag cacaagctct gcaaaagaat ggatcgcaca aaaagaatca
      241 agcggttctt acacagcaac gaacggacgt tacatcggac gttaccaatt agattcttct
      301 tacttaaatg gtgactactc tgctgcaaac caagaaagag tagcagaaca atatgttact
      361 tcacgttatg gttcttggga agcggcgaaa gcattctggg aagcaaacgg ttggtactaa
      421 gattcattta ttaatcaaac agtttacttt tatacaaaga aagccaaaaa gaggtgcgac
      481 actagttgtg tcacatctct tttttattta cctaatctaa tgaaacgttc caagttttga
      541 taagtatttt ttttaacttc ttcaactgat agctctttga tctcagcgat tgtctttaac
      601 tgttcttcaa gcagtgagac ataatctttt tctgaaaaaa tcccccctaa agcccactct
      661 gctgcatgta gtccatccgt ttcaataagt aagtggtcga ttgggactgc tttagctagt
      721 tgccagactg ctggattctt tttcaaatca agaccaatgc tgaaataaca gcctaaatca
      781 atatagtctt gttgatagtc caaagaagaa taccaatgga tcaaatagtg attagggtaa
      841 gcttggatat aatttaagat ctctttttcg catccttttg tgtgcagtac aacaggtttc
      901 tcatttatgg ctgcaaaagc aagctgtcgc tcaaatactt ttttttgtgt agtcatcggt
      961 acattcgtcc aaatattatc taaccctatt tcaccgatga tccttgcttt tttcaaaaaa
     1021 ggctcaactt gttcaaacgt atagctatct gctttccaag gatggatacc gtaacttaag
     1081 gcttgagtct tacttgctgc aagctgtctg ttttccttcc attcttctgg cgaatcacaa
     1141 ttgatgatcg tcaaaatcgt gtgttcctgc tgaaggagtg ctaaactctg actcccatct
     1201 aaatgacaat gagcatcact taacatctaa ttcacctgcc aataactgat aaatcgtttg
     1261 cttcaactct gattgctgca gtagccattc acgtgaccgt cgtttttcag gcacttgaat
     1321 ctcagcaatc acatgtgccg gacgggcgga aagcacaaga atcctgtctg ataaataaat
     1381 tgcttcttcg atatcatgcg tcacaagtaa agtagtccgc tttgcttttt taggcagctt
     1441 caacatccag tcttgcatct gccctctggt catagcatct aacgctccaa atggttcatc
     1501 aagaagcaag taagaagaag gattcatgat tgttcgtaac aaggccgttc gctgcttcat
     1561 cccgccagat aattgttccg gcaaaaaatg ttcatagccg tttaacccaa agatatccag
     1621 ataatccctt acttgttctt cattgattgt tagatgattg attttttgat ataacgtaac
     1681 gttttgatag acgctcagcc aaggaagtaa catatcttct tgcggcatat aactaaatgc
     1741 tgtatggaga ccagttactt tttgatcgtc tactttgatc gttccagaag tcataggctg
     1801 gactcctgtt aaagttttca gcaatgttga cttaccggct ccgcttggcg cgacaatcga
     1861 tgtaaaggta tctttaggga tagtgaaatg gatgtcttct aatattttca ggttttcaat
     1921 gactacattc aagtggctga tttggattga catatctatc actcctattt tataaactga
     1981 ttagtgaata gttcttgcga aggtacatct tgcttgatca atccgttttc ctgcataaaa
     2041 gctgtataat tgcgccaaac tttttcttcc atcaatcccc aattctcagg atcatccgta
     2101 taattttttg acaagaatgc ttgtgattct tctaaaaacg tccgatcatt ttcttttgca
     2161 tatttttgca acagtttagc actgtcattt ggatccttaa tagcttcctg atagcctttt
     2221 ttcgtggcat ccataaaaga ctgtaccaat tctggatcac ttttgatcag ttgatcattc
     2281 gtaataatta ccggagtata gtaatctaac cgttcatcta attctttcaa tgggatatag
     2341 tttagttcaa tacccgcttc ttttgctttg atcatatccc aaccttcaaa gtaccattgg
     2401 atatctgagg attttcctaa gctttctggc ccttctccat tgcttcctac cattgtcagt
     2461 tttgaaaagt ccccgccgtc tttttccatc acagctttta agacagcttc ttcacttgga
     2521 ctttgccaac ctgcatatgt ttttccttca aaatcttttg gtgaatggat gttactgtct
     2581 gatagggtgg cgaatccaga agtattatgt ttgatcactg tagcaattgc tttgactggt
     2641 atattctgtc catctgcgtg agcataagtg acatcttctt gataacttac accaaattgt
     2701 gctttgtccg cacctactag accaatactt gtcgaattat ctcctggttc gatgatttgg
     2761 acatttaaac cagcctcttt ataatagcct ttttcttttg ctaggtagat gccagtatga
     2821 ttagtattcg gtacataatc caaaacaagt gtcacttttt tcaaatcctt tatttcttgt
     2881 ttgctacttg tttcttttgc agtgccacaa gcggataaaa gcaacagtag cggtaataaa
     2941 agccataatt ttttcatttg atccccttct cttaaaaaat ataaagcata cgataatacc
     3001 cttttttcaa taatgaacaa gcgccattca gcaataaact caatagaatg acacaaatga
     3061 tcgcagcaaa aactttatcg atctggtagc tgttttttac gcgtatcatg taatacccta
     3121 agcctgcttg agcgcttagc cattctccaa cgactgctcc gctgacacaa taagtagcag
     3181 ccacttttaa accggaaaag aagccggata aacccgctgg tattttatat attcgataaa
     3241 tcttccctgt atctgccccc atcgttttca aaaagatgat ttgctctttt gatactttcc
     3301 tcaatgtatc cgaaaaagaa actacgatcg gaaaatagct tatcaagaca acaaggatca
     3361 cttttggaag cataccgaaa ccaaaccata gggtaagtaa tggccctaac accatgattg
     3421 gcaacatttg tgaaatcact agtaacggat aaaaagacat ttctaaaaac ttccaataat
     3481 ccattgccaa ggcagtaata aaagaaagaa cgctagctat taccaaacca agcactgctt
     3541 catttaatgt cgtgacagaa tgggaaagta atacttgtgc atctgccgct aatgcagaaa
     3601 atacagcagc aggtccgggt aaaataaagg caggtatttt ccaaactatg acaacaatct
     3661 gccaaataat taaaatgaat gccatactga ctgctggata aagatttttc ttcattttgt
     3721 tacctccttt cttctaatat gaataacaaa aaacgcttga aatgggcacg acatagtaac
     3781 ccgcttcaag cgtctgctat gtttctccct tcaccagtat taactgacag gttcaatggg
     3841 tctaagttca caacttactc tcatgtcgtc tacgacatcc ccagaaacag gtattcattt
     3901 tttaaagtgt agcacaagaa ggaaaaagca acaagcgctt tagttatcat gctgattatt
     3961 tcaataaata ggagagatca cttgccaatg tcggataccc catgatatag ctatccaact
     4021 cttttttagt caatttttga ttgatgacga gtgtcaaatc atcgatcaat tcgtctgctt
     4081 gctcgctaat cactgcagca ccaatcaaat aattttgctg gtcaaaggtc aattcagcct
     4141 tagcaactgg ttcattgaca cgatgatagg tgaaccaact ggtaagatcc atctctacca
     4201 cttgatctga cgaagaggcg tgactttttg taactcctac ttcagcaagt ttaggactgg
     4261 cgtagacgat cgtaggtata atcggatatt tgataggttc gcttgttgca tccgttatcc
     4321 gcttagctac ataatttcct tcaaaagtgg cgactggtgt caattttggg gttttccttg
     4381 aaacaatatc tccacacgca aaaatttttg gattgctcgt ttgcagataa tcattgactg
     4441 caattccgtg tttatcaaag acgatattcg cttgctcaag tgctaaagat tctgtattcg
     4501 gctgtctccc agtcgcacaa aaaatcatat ctgctactaa ttccgtctct tttccgacta
     4561 aacgatagcg agtaccttct gaaatgatct tttgggtttc aacaccaaaa gcaaactgaa
     4621 tgccagatgc ttccatttga tggacggctt cctctaccaa agacgcctca aattctttta
     4681 atggccgttg attatgatgg acaatggtta ctttgctccc tgcagcattg gcaatcgtag
     4741 ctagctcaaa agcaatataa ccaccaccga taaaaatgat ttctttaggc agtacaggca
     4801 atgataaaaa gtctgcacta gttttcaagt attcctttcc ctccactggt aagatcgtag
     4861 gtctttgccc ggttgccaaa actaagtaat ccgcatggaa gacttcttcg ttgacttcaa
     4921 tagatgaatc atccaaaaaa cgagcggttc ctgaaagatg atcgatttca gcttctgcta
     4981 attgtttttt tcggctttct gggactggat ccgtaaatgt tcgtttgaat ttttgaagtt
     5041 cttcccagtt ggcagttggg atctcgttaa aaccttttcc actcaattgt tttacccgat
     5101 tacgtgcctc tactgcactt aacaagactt ttttaggatc acatccacgg ttaggacaag
     5161 tcccgcccca tagatcttct tcgaccacta gtactgtttt acctgcttct ttcaatccat
     5221 aagcagcact taagccgctc acacctgaac cgatgatgat tgcatcatat gttttcattt
     5281 ccttcctcct ctcgacttaa aaaagcaaag atttctttac ttgtcagcga cccaatactt
     5341 ctttgctttt ctactatcac aatgcttgga tacaccgaaa gaagcgaata tacttctttc
     5401 ataggcgtat caaagcaaac ttgttgacga gcattttctg gtatttcatt taagaaatat
     5461 ccattgacga ctaaatcttc tactcgccac tctttcgtct gtttcggttc atcaaagaaa
     5521 tgccgaacgt agtcgttttt aggattcatc aataactgct ctggtgtgtc acattggata
     5581 atttctccat ccttcataaa tgcaatacga tcacctagct tgattgcttc ttccatattg
     5641 tgcgtaacga aaacgatggt cgtgcccaat tcttcgtgta aggacaaaac caattcttgt
     5701 aatgagtttc ttgaaatcgg atctaatgcg ctaaatggct cgtccatcaa aatcacatct
     5761 gggcttgcag caatagctcg gatgatcccg atccgttgct gttctcctcc agacaactct
     5821 ctaggcatac gatctcgata aatatcagga gataagccaa ctttttgaag aagttcatct
     5881 acacggtctg ctcttttctg cttttcccaa cctaacattt cagggatgac ttcaatattt
     5941 tgcttgactg tcatggtcgg gaacaaagcg atttgctgca gcacatatcc catattccac
     6001 cgcattttct gcagattata ttcatttaac gattttcctt tgaagtagat gtctcctgct
     6061 gatggtttag ataatccatt gatcattttc aaagtagttg tttttccact accggaagga
     6121 ccaaccaaaa caaagatttc tccttttttg attgccagat ttaggtcatc gatgacatac
     6181 tttccatcat actttttttg cacatgtttg aactcgatta atttagtcac tgatcttcct
     6241 cctttactaa tccttcattt ttcaggaaga ttcgtgctac ttctgtcggc tttttctttt
     6301 cgacattgac ttggtaattc atatcaatca tttgatcctc tgttattttt ccgcttaatt
     6361 tattcagtgc tttaacgatt tcaggatgtt ctttagcaaa atcttttttc atcagcggtg
     6421 cgccttgata agctgggaat aaccctcgat catcttctag agtcactaga tcgtactcct
     6481 tgagctggct atctgtggaa taggcatcca caatattgac atctccatta ttgattgctt
     6541 ggtaacgcaa acttggctcc atgctttgta cacttgaaaa attcaagcca tatgcttctt
     6601 ggattccttt atatccatct gaacgatcaa taaattccag tgtgaatccc gctttgatct
     6661 gatcagagat agctgccaaa tcggaaatct ttttaagttg atgttcgttc gcaaaagatc
     6721 tcttgactgc caaggcatac gtattttggt aagccattgg ttttaataat gtcatatcga
     6781 attgcttatt caataattct tctgcttcgt catatgtttt ttcttttgtc aaatcagcac
     6841 ttttcattgc ttcaggtacc ttcaccaagc tttctaggac agtacctgtg aactcaggat
     6901 agatatcgat ttgaccttga tccagtgcat tgaacaaaaa actcgtcttg ccaaaattcg
     6961 gttttaattc aacttctgtt tttgtgttgt cttcaatcaa ttctttatac atttggatca
     7021 ggatttcagg ttccgctcct aattttccag caatcgtgat ggtttcattt ttaaacaagg
     7081 cagactgata taaagaaacg ccgccaaata aacacaccac tgctgctaaa gtaatgatgg
     7141 aatatcgagg tttcttatgc tgcaaccagc gaatcagtcc gctgaatata attgcaagca
     7201 aggcagaact gatcgcacca atcaatgtca aaacaggtgt atttcggtca atacctaaca
     7261 aaataaatgt ccctaatcca cctgctccga tcaatgctgc caaagtagcc gtaccgatga
     7321 ttaaaactaa ggcagttcgg atacctgaga taatgacagg taatgcgatg ggaagctcta
     7381 ctttcagcaa gcgtctcatt ctggacatac caaatgctac cgctgcttct tcaatagacg
     7441 ggtcaatttc agctagacca atatacgtgt tttggaaaat cggaagcaaa gcgtaaataa
     7501 caagtgcaat caatgctgga acagttccga tccctacaaa tgggataagt aaacctaata
     7561 aggcaagtga aggaatcgtt tggagcacac ccgtgatctg caataagact tctgccattt
     7621 ttttatgatt ggctgcccaa atcgctaaag gaatagcaat cagtgctgca atcagcaaag
     7681 aaatgagaga aatggacaga tgttgaaatg cagcttccag caactcgcct tttctttcac
     7741 ttaatgtttg tataaaatta ttcatgcgac cttcctttct gttattcttt aagtataaac
     7801 atttctttcc tttttcccaa ctaacttgtc ttgccttaac cttacagcac gaacaaaaaa
     7861 aagaaaaaaa tacctctaaa tatgctgaca aaaaaagaat ccaagcaaca aagtcggatc
     7921 aactttttgg ttctcgtttt ttcactacga ataccataaa aatctatacg aaattgtcac
     7981 ttggaatcag ctatatcttt tttacacaca caacttttat tttaataaaa agaaacagcc
     8041 aataaagtag aaatctcgtg ggggagaaca cctttattgg cctgttcaac gaatattata
     8101 ctgtatcatg acactttttt gccaaaaatg taaaaaatgg ttgttttgac atcataaacg
     8161 tcttgttttc ttatttttac ttatatcacc actttatttt ctatctcttt cactccataa
     8221 agaggaatga gttcttcttt tgactgataa taaacagctt tctcacggtt cttcatcaaa
     8281 aaaagaaaga tgtctttcat agcaagtggt gctttgccgt gttcaaataa aaagataaat
     8341 tgatttgctt tatttatctg gaccattgtc acaggcacca gtttttgttc ttgagccaaa
     8401 aaaactcctt gatactctgt ttttttgggt gattttgtaa gaattgtcaa taagtctgct
     8461 gctcgcattt ttccactcct tatttgataa ataaaaagaa acagccaaaa ataatttttt
     8521 ttcattttcc tcttgaagta agagtataag tcagtataat aaagaagttg ctgaaaattt
     8581 tcaaaagaaa agaggctaga aatgaaaaaa ttaaatttat ttacagaatt gtgcggaatc
     8641 attttaggcg caggaatcta cggattagct gtgacaggaa tcaatattcc atctaagctg
     8701 gcagatggtg gggttactgg tattgctttg cttttgcata atctttttgg attcgctcct
     8761 tctgtcactt cactgctttt taatttacct ttattgctta tctcattgtt tctttttgga
     8821 aaacacgctt ttctccggac gatcgtcgga acatttgcgc tagttttctt tttacattta
     8881 tgggagagcc ttcatataca ttttgctgta gatagtctac tgatcaatag tttgatgaca
     8941 ggtattcttt ctggcattgg ttgcggtctc gtctttcgat tcggcggaag cacaggcgga
     9001 acagatatca tttatcaagc cattgaaaaa tattttcata ttaagattgg caaaagtctt
     9061 ttcttgatta cttttggtat tttagttgtc tccttgcttt atttggatct cacacatttt
     9121 ctgtatacat tacttagctg ttctattcta tcttatacat tgaataaagt gaagtatctg
     9181 gaaattggat ctgttttgcc ccaattggaa gcaaaacaga ctacagaaac atttgaacca
     9241 cttgatcctc ttgaacagtt agagcactga ttcttatttt tcactacttt atttaattta
     9301 cagaaatatc attatgtaaa ctaaaatgat attattcagt aaaatcttct ttataaaaaa
     9361 ataaactatt tttgcaaacg atctgcgaaa atagtttgtt tttttatttt gccattattt
     9421 tcttacttat tgggagaaaa aattcgctta aactcaaaaa aatttgagga tacgatataa
     9481 actttcggat agagtataaa ataaggaaac gccgcagcgt ttcctttcca actgtagccg
     9541 aatataaatt tgtatatcac ttatttaaaa tagctatttt ctcccaaaga gtttccttga
     9601 tcatcgatca atccttgtaa tgagcgttct aagataccat ggcttttttt cgattttttt
     9661 tcttctgact gctttgtttc ctctaacgtt tttgttcgat tgaatgttcg tacagacggc
     9721 tcaccatttc ttttttcttg atacggcgtc ggttctgtat cgaacaacag ataagagtca
     9781 tccgtttttt tcatcgattc gattaaatga tcctcagaaa ttttgctttc tctagggtct
     9841 gggataatcg atgcgggtac atatttagga acaaaataag aacgctcccg caccttcgtg
     9901 tcaacagatg cgtttcgtgt agtatgcttg gactctgtcc ttgtttcact ttgtctgaca
     9961 gaacgagagg aatcaccaaa aagttttttt cgtcctgtcg atgtgatttc tgattggtaa
    10021 tggccggtat aatccggtaa ttttccttta tgcttttcca aattttcctt acgcggagct
    10081 gacttcaatc catttgttgc acgacgcttg cgacggattt tctcggtgtt cgtgttcgtg
    10141 aaatgaaatt ctttcatctg ttcaaacggg gactgattct gttcagtcaa aagatcttct
    10201 tgtccgtcaa ataatactcg cttcttgtcg ttggttaatt ttacgcctaa ctcatcatcg
    10261 tacgcaggaa aacggaaatg ttttcgtctg atttctttca ttcaaaccat ccttctcaaa
    10321 aatggaactt ttctcaataa tagcacagat tcattgtttt cagtagcaat gcgctgatta
    10381 ttttaagaaa atagcgatga atttcataaa tatatatata gtaataagac ttaattcgtt
    10441 gtctctctga taactagttc aggaaaaaaa cgacgataac cttgactcgc ccctttttct
    10501 tctatttttt ttaacaacat ttctccacat acttcaccca tacgtataat atcttgcttg
    10561 atcgttgtca atttaggtga actgatttgg tctaaaaata ccccatcaaa tccaatcaca
    10621 ccaaattctt cgggcaagtg tcctccagca tttataatcc ctcttactgc tcctagtgct
    10681 agccgatctg aactacatac aaaacaagtt ttatctgtaa aatctgccca gttttctgtc
    10741 atatatcttt ctacttctgt cgaatgattt ggaaaccgca agattttact aggaagatca
    10801 acttccttca tcacagataa ataaccagtt tcccttgaaa tttcaaaagg ctcgtccact
    10861 tcgataccga tataaataat cgtttgataa tctctttcta aggcatattg cgttgctttt
    10921 gctgtaccat attcattatc gctgtctaca taatcatatc cttcagaatt ttccccaaac
    10981 aagacaactg gtttttccaa acggtcgatc caatcgaagt ctttttttct gacacctgtg
    11041 atgatgtatc catcacaaga accgacgtcg aaggcatcat ttgtaactaa ttggagagaa
    11101 taatgcgctt taccgatccg tttagcgatt cccatcagca aattcatgta atagggctca
    11161 gttgtgtcga tttcttccag tataaataat ttgatgatct gcgaccgatt cgtgacaagt
    11221 gcttttgcag caatatttgg acggtaatcc agttcagcca ttgctgagaa aactaactct
    11281 ttcaattcgt cagtcacctg ttccggatga ttgatgactc gagagaccgt catttttgaa
    11341 acattggcac gttttgcaac atctgctaaa gtgggcatgc tctcttcctt tctaacatgt
    11401 tgtcattctt actatcaatt ataccaaatt ttcctaacag agtttattat agcccaaaat
    11461 aaaaaacgga aaatcctcta tcgtcatgag tgattttccg tttcaattat ttatactttt
    11521 ttatcaaatt ttttgctaaa aaagtggaag cttcttccat tagtggtatt tgtaccatat
    11581 gtcgctgtgt ttttgaggaa cgaaaaacaa tttcttttcc gtaagactta tgccgatttt
    11641 tttctacaaa tcgttccgtt tgtatataag ggattttttc gtcagcttgt ccatgccaaa
    11701 agaacagagg acgtccagct aacttttccg gctgcaatga caaatcatag ctcttaaccc
    11761 atgaaatcaa atcaaaatag tcttttggta cgacataatt atattccgat gcgcgcctta
    11821 cgatttcttt tccatattcc aaaggtgcag gggaacccat caaacacacg cccgctacta
    11881 tatgaggatg tttagccaac aaggcgcatg ttgtcattcc ccccatcgaa accccgccaa
    11941 ctgcaagctg atcatgtaga agacctcttt tttctaaatg cttgataagt gtgtcaaatt
    12001 caaacagatt tccgtagata ctatcccaaa atgtatagga tggaatagaa gaaaccggct
    12061 gtttgcgctc cccatgattc atcgcatctg gcaggatcac acgaatgccc tgctgcgcaa
    12121 tttttcttcc ttgcgtcaaa actaactcct tacttgtctg ccatccgtga taatagatga
    12181 caacgggaat acgttcctct cttaattctt tcagaacaac ttctaacact ggaatatgat
    12241 ggacagaacg tttcaatata attggattca attgttactc acctattttc attaaatttc
    12301 ctgatcgcca tagcaaccat gctccaacag ttgtctggaa caggttcagt gtaccaaata
    12361 atataaatgc aggactgaat ggctcgggaa ataagcacag agaacaaagt cccaccactc
    12421 ctaatgctag cgaaaggagt ggataaatag aaaaattcaa aaaactggca acgctaccga
    12481 aaatattacc aataaacagt atcaaaaaga aaaaaacgct taaaattaaa ccatctgtca
    12541 gcgacatctg aaaaacaatg ttctctacct caattggctg ttgaatcgaa tagacaccta
    12601 agtatatact gagaaggaga cttagcacgt ggctggcaca aaacacacga ttgaccgttt
    12661 tcattttaat cacctaacct atctttataa ttctattata atcattttat catttttttg
    12721 tatgtataaa gtttcaattt ttcttcactt acgatttttt ttgatattgt tgttatataa
    12781 atgaaaggag ttttacaaat gattgatcca aaaatgttgg ggatgatctt cctcattaat
    12841 tttgcttata tcactctgaa cacgttacgt ttcatgttga caatgaaagg ctatcgactg
    12901 attgctccac ttgtcagtat ggtcgagatc acgatttata tcgtcggctt atcccttgtt
    12961 ttagatcgtt tagataatcc actgaattta tttgtctatg cgttaggtta cgcagtaggt
    13021 atcagtgtcg gaattttgat tgaagacaaa ttggcattag gatacatcat ggtcacaacg
    13081 attttgccag caaatagcgc agaagataaa agtttgccgg gtatactgag agaacacggt
    13141 tatggtgtga cacagacttc tgcaatgggg ctggaaggtg agcggctagt tctcgaaata
    13201 ctttctccta gaaaaagcga acgtgaactg tatcgcctga tcaaagaaat cgaagagcgt
    13261 gcttttatca tttcttatga gccaaaatat atttcaggtg gtttctggac taaaaaagtg
    13321 agaaaacgac aaggaaaata actcacaaac ttaaaaactg tctaatatct aaattaaatt
    13381 ttaaatgtta gacagttttt atttattatt ttgattaaaa aacatcgaca tatactcatc
    13441 aatttgttat tatactttat atacttatca atttaatttg gagatattat ggaaattcaa
    13501 cgtagaacca ctaatttttt acatttaggc tctttttttg caactttgac gatcttattt
    13561 tttctatgtt attcatacct taagacctca catgcgcctt ctagtgcatt aggctggttg
    13621 cttttggatc attctgatat cacagaagcc gaagaaaatc cgtttttttt gattttgtct
    13681 tctctttgcg gcttactgtt ttctgtttat ttcggtgcct atttttttca tcgacatcct
    13741 ggtacgttaa acgaagcttc aagcgtattg attgcattta aaacgttttc ttttttagca
    13801 attctttttt attcgtttaa tcacaatacg cttttcttct ttatcatgaa tggtttagtc
    13861 gtgattttat ccatttttac ttattttatt ttttcactca tttttagcca attgaaatgt
    13921 ccgctcttct ttcgattagt tcctgtcacc tgttttattt acagcttgtt ttcctttttt
    13981 gtccttgctt taatgccact gaccaaccct tcgacgatcc aagtcgcagg aaatctgttg
    14041 gatatgctct tcatcgtcag tctaggtgta tttatgtggc aaagaaaaaa caaacaaaat
    14101 aaaaagcatt ttgaagcctg actattacga cttcataaat gcttttttag ttttaaacac
    14161 ttcaatctaa aagaataacc caagattgga taaattatta atgactcgcc attcgtttct
    14221 tagtgattct ggattatcaa atggacttcc taatctaatc agctagttct tcccataaaa
    14281 tgccatactt gactgaatca taatattgat tatttaaaaa tctaactttt cttatcacta
    14341 cttcctttgt cattccacat ttctcaccat ttttttgcat tcctttgttt ccagaccatg
    14401 tagtgaatct aataggtggt agataggcaa aatactcaaa taattctttt aaccataaag
    14461 gaagagaaag gctcctcctg caagagtcag tataattttt gcttactgct ctcttaggtt
    14521 ttactcacta aaactgttcc atattctttg atataagaaa atgcatgcgg tataaatttc
    14581 ttgctcagct cagaaaagat ttgtcgttta agaaaggcta tttcctccat tgtcaatgaa
    14641 ggatccaatg ttggtaattc aatctcaaaa ttgttttttt cgacaatagg taattctaat
    14701 gtgaatgatt cttcttcctt tatagtattc gtcacaagta gagactgatg gaaaatacta
    14761 ggccggcgat ttttatattt attcttacgt atcctgtcaa cgataacttc tatttgatca
    14821 aaaaagtacg attcatttac gtctccaata agttcggcta attctttgaa tgccttcgtt
    14881 acaggaagct gattcttctg tacaaaaaag taattagcca aagtaagcgg gaagtgttct
    14941 atagaggaaa gtgtgataaa acggtacttc tcatttcctg cagttgtcct cagcaattct
    15001 gtctctcggc tgtttcttac tccataaaaa tacgcttctt tccgttcatc ttcgaaacaa
    15061 tacgcccaaa taacttctcc catcgctaat ttttgttcat caacagagag tctcttcaat
    15121 tgttcagcta tggtttcagc agccgaagtg gcttgttgca agtaatcttt aggatcaaat
    15181 attggaaagt tcaaatgata tcttcgttct tccctcttga ttaatcctgc atcgatcaat
    15241 aaatcaagaa aatgggaaaa tttattttgc gaaaattctt ttttcaattc tcttagaatc
    15301 gtttcttgtt ctcgatgttc atatagataa tcggtcaatg aagaaaaaag cggatcatcg
    15361 gtcagttttt gataaaagtt ttccttattt tttgaataat agttcatata tgttctcttt
    15421 tctatccgtt ttattttact taaaaggctt ttacgtaaaa aggaggaaga acaagagtca
    15481 taattgactg ttattctcct ccatttcttc ggcctttagt atgttctatg tttcttttta
    15541 tatcaatcgc ttatccattc attttgaatg cttcatacta ccatttgatt agctaaatac
    15601 agccgtcaat tgaggtacga cttgtttttt acgtgaaacg acacctttaa gcaaagcacg
    15661 gttgttggtc aaagttgttt ggaaagcttc ttctactttt tcttttcctt taccagcaac
    15721 aagtaattct gaatcactgt ctaagatgtt tgtgacaact aatacgaaca gatcgtagcc
    15781 atttgctttc atttcatctt ccattgctgc ttctagctct gcttgtcgat ccatcacttc
    15841 attaaggtcc actgtattga cttgagcgat acgaacgttg gaactgccca ttgggaaact
    15901 ttttgcatcc aaatcaagaa gaaccgcagc tgatttatca cttagatttg ttcctgcttt
    15961 caacatttca agtccataag tgtttagatc gacttcagcg attgctgcaa gttcttttgc
    16021 agctgcttca tcttcaggcg tacatgttgg tgatttgaac aacaatgtat ctgaaatgat
    16081 agctgagagc atgattcctg cgatttcttt aggaattgtt acttggtttt ctttatatag
    16141 ttttaaaata atcgtacttg tacatccaac tggttctgca cgatagtaca atggattagc
    16201 tgtttcaaag tttgcaatac gatggtggtc tactacagct aaaatattta cttcgctgat
    16261 atctgaaata ctttgttgga attcattatg atccacaagc atgacatctg cattttctgc
    16321 tttagctgac tctactactc gtggtgcaga tagctgaaag tggtctaatg cgtattgtgt
    16381 ttcttcatta ggtgtaccta gagcaactgc ttctgtttct ttacctaatt cattttgcaa
    16441 gtgtgaaaac gcaatggctg ccccgattgc atctgtatct ggattttggt gaccaaaaac
    16501 taaaattttt gacatgtcat tcgctccttt gtgatttctc ctatttaata atagcaaaaa
    16561 aacggaaaga agcaatactt atcttctttc cgatgcgacc tatcgcgtta aatattttgt
    16621 atactcttct gtatgaagca atcgtttagc attttcgaca cgttcttttg taggtggttc
    16681 gatcccttct aatggatatt tcaaaccaag tgtttcccac ttgtattttc ccatcgtatg
    16741 ataaggaaga atctctactc tgtctacatt tgacaaggtt tgaataaagt tgtctagtcg
    16801 gatcaaatat tcatcataat cacttcgctc aggaactagt acatggcgaa tccaaaccgg
    16861 tttgttgatt tttgacaaat attgagccat ttctaaaata ttttcattgt cccaatgcgt
    16921 tagtttttta tgctcttcat tatcgatgtg tttgatgtca aataacagta aatctgtata
    16981 cttcatcaat tcttgaaaac gtgaaaagaa aggttcttca tacgtaaaag gttttccgca
    17041 tgtatccaat gtagtatgca tcttccgctc ttttgctttt ttaaatagtt cgatcaaaaa
    17101 atcgatctgc aatagaggtt ctccaccact aacagtaata ccacctttat ctccccagta
    17161 aggtctgaag cgttctgctt tatctaaaag ttcatctgct gtgtattctt tccctccgcc
    17221 aatattccaa gtatctggat tgtgacaaaa ttggcaacgc atgcggcatc cttgcataaa
    17281 cacgacaaag cgcagtccag gtccgtctac tgaaccgaaa gtttcgatag aatgaacata
    17341 gccgattgtt ttttcttcca tttaagttca catcttttct ttgatttcat tttaagtaca
    17401 agttagctgt cgaagcgaag ctttctgaac aaaatttttc gcaattgccg cttcgttatg
    17461 tgtaaaattt acagggacgg aacatacaag tcctgcccct gtaaatcgtt tctttcaaat
    17521 aagcatactg attattcgat tttgatgcga tggctattca acgtcctttc gacgctaagt
    17581 cgaaaaactt ttttcacgaa ctttttacat tctgtcgtgt gaagttctca tcaagacatc
    17641 taattgttgt tctcttgtca agtcacggaa tttaactgca taaccagata cccggatcgt
    17701 caagttcgga tatttcattg gattttccat tgcatcacgc aataaatcat tactgaatac
    17761 attgacattc aaatgataag ctccttttga gaagtatcca tctaagacat tacgcaagtt
    17821 ttcgattctt gtatcttgtt cttttccaag acctgaagga ttgattgttt gggtatttga
    17881 aattccatcc aatgcacagc cgtaattcat tttagctgtt gagttcaggc tagctaataa
    17941 cccactttgt tccgcattgt aacttggatt tgctcctggc gcaagtggtt ttccagcttc
    18001 acggccatca ggagtatttc ctgtattttt accgtaaaca acatttgaag taatcgtcaa
    18061 taatgaagtt gttggttttg agttgcggta agttttatga cgtttgattt gtcccatgaa
    18121 gtattccaag atccatgaaa ctaattcatc tgcacggtca tcatcatttc cgtatttagg
    18181 gaagtcgcca tccacttcaa aatcaactgc tattcctttt tcattacgga ttgcttttac
    18241 ttttgcatat ttgatcgctg acaagctgtc tgccgcatga gagatcccag caatacctgt
    18301 agcaaatgtg cgttgcaagt cagaatccat caaagccagc tgagctgctt cataagaata
    18361 tttatcatgc atataatgaa tgatgttcaa cgtattgaca tatagttctg ctaaccaatc
    18421 catcatattc atgaagttat gtttcacttc ttcaaagtct agtatttctg atgtgattgg
    18481 acgatattct ggtccaactt gggcgccagt cacttcatcg actccgccat tgatggcata
    18541 taatagtgtt ttagccaagt tagcacgagc gccaaagaat tgcatgtctt ttccgacaac
    18601 tgttcctgat acacagcaag caatcgcaca atcatcagaa ccccattgtt cacgaagctg
    18661 attatcattt tcgaattgaa tcgaagaact ttcgatagcg attctgctag catatgttct
    18721 gaatccttct ggaaggtgtt cagaatacaa aacagtcaag tttggttctg gtgaaggtcc
    18781 catatttgtt aatgtatgaa gcagacggaa atcattcttt gtaactaatg aacgaccatc
    18841 taatcccata cctgcaatgg ataaagtagc ccagataggg aatcctgaga ataattggtt
    18901 atattcaggt gtacgcgcga atttgaccat acgtaatttc attactaagt ggtcgatcaa
    18961 ttcttgtgct tctttttctg tgattactcc attatccaaa tcacgttgga tatagatatc
    19021 aaggaatgct gagatacgtc cgattgacat cgcagcacca ttttgtgatt tgattgctgc
    19081 taaatatccg aagtatagcc attggacagc ttcttttgca tttgcagctg gtttagaaat
    19141 atcatagcca tatttcgcag ccatttcttt catttgcgct aatgcacgat attgttcagt
    19201 gatttcttca cgtaaacgaa tcacttcttc actcattgta tgataaccag tcatatcatg
    19261 atcttttttc ttttgttcca tcaaatagtc gattccatac aatgccacac gacgatagtc
    19321 accgatgata cgtccgcgac cgtaagcgtc tggaagccct gtaatgattt tgtttttacg
    19381 agcagcacgc atttcagcag tataagcgtc aaatacacct tgattatgtg ttttgcgcca
    19441 gtcagtgaaa atatgtgtca attcatcgtt tggtgtatag ccattgcttt ttagcgcatt
    19501 gttagccata ttgattccgc cgaacggcat gaatgcttgt ttcaaaggtt tgtctgtctg
    19561 tagaccgacg attttttcca aatctttatc caaatagcct gcatcgtgtg aagtaatagt
    19621 tgatacgatt tctgtgtcca tatcatagac accgttacgc tcgaattgga tatcatttaa
    19681 cttttgcaat tcatcccata atttttctgt tgcttctgtt gggccttcca aaaagctgtc
    19741 atcaccgcga tattcagtgt agttattttg aataaagtct ctagtgtcta cgccttcttt
    19801 ccatttggta cctttaaatc cattccattg ctccattgta tggacctcct aaatttctgt
    19861 tttatgtaac agtttttacg tgattagtat aacacagcac cctatctttg caagggtttt
    19921 cttgtttttt atttaacaat ttttatgttt tatttacata tatttaaatc aacgttgaca
    19981 taccaacatt taagcattgt gaacactttc atcttttttt gcaaacgtat aaggatttat
    20041 taaaaatgaa tgaaaaagag acgccacctg tattaataca gatggcgtct cttcattaaa
    20101 atactacaac agttacgact cgatgaaaat ctcaggagca tcgataactt cgatgacttc
    20161 tccacctttt ttctcatcca tcgcaaatga tccattcgat gttcgatcac ctatagggaa
    20221 atcagttggg tcaatcgtta actgctgccc tttttgattc atcaaggtta tttcttttga
    20281 tcttccttcc gacatataga taatacggtg cggatttttt ttcagctcac gcatgaccgt
    20341 cactccccgc ttcgcacgtg aagtttggct gatttcttga gcaagcatgc gtttaacagc
    20401 tcctcgctga gtaacgatta cgatcggcgt atcaccttct gctaacacaa gcagcccgtt
    20461 gataatccta tctccatctt tcaaattcat agacttcact ccagctgcct ttgctccaac
    20521 aacgggaaca tctgttaaag gatagcgcaa acccattcct tgatgcgtta ctaagaaaac
    20581 atctaagcct ggctgatctt ctttcagata cacagcaatc agttcatctt cttccgcctt
    20641 tagcttcata cagctgagcg gacggctctt ataggtgcgc catggttcga actctgtcat
    20701 tcgtgtttgc ttgatcaatc cattcttgct gatgaataca aatgttttct ctgcttgaat
    20761 tttttgatat gggaaaacag ctaaaatcga ttcgtctaca gacagattgg agattgtttg
    20821 agaaatgtgc tcaccagcat ctttccattt caaatcgggt agttcatgga cagggcggta
    20881 gatcacattt gctttatttg tgatcagaag aacatggtcc aatgtactca attcacctga
    20941 gtatagcaag tagtcgcctt ctcgcatccc gatttcttct ggtttggaag cactataaga
    21001 acgaaggctt gttcgcttca catagccttc tcgcgtcaca ctgacaatta cgtcttcttg
    21061 tgccactaag acttgcgtat caattttgat ttcttcgatt tcgtcttcga ttgtcgttag
    21121 acgagcggaa gaataatttt ttttcacttc tcgcaattct tttttcataa cagagaaaag
    21181 ctctttgtca tttgaaagga ttttattcaa ctctgtgatt tgcgcaatca agctttcgga
    21241 ttccttttga agctctgtga tatccgtgtt cgtcaaacgg tataattgca atgtgacaat
    21301 tgcttctgct tgttcttctg taaattgaaa gacgtcgact aaattctttt tggcgtcttt
    21361 tttgtcttta ctttcacgaa tcgttgcgat tacttcatcc agaatcgata aagctttcat
    21421 caatccttct acgatatgct gtcttttttg agctttggct aaatcgaatt gactacgttt
    21481 tgttatgact tgctttcgat gctcgatata acttcttaaa atgtctttca gtccaacttg
    21541 atgcggagtc atatggtcga tagcgaccat attgaaattg taattgatct gtagctcagt
    21601 gtttttgaac aaataattca aaattccttg agcattggcg tcttttttca attcgacgac
    21661 aatttgcaga cctgttctat cactttcatc tcgtacttca gctattccat cgattttctt
    21721 attcaaacgg atctcatcca tttttttcac caaggtcgct ttatttactt catatgggat
    21781 ttctgtgatc acgatttgct gtttattacc cttcattgcc tctatctttg ttttcgaacg
    21841 aagaataact tttcctcgtc ctgtttcata agcttttttg atttcatctt ttccttgcaa
    21901 gatccctcct gttggaaagt caggtccagg aatatattcc atcaattttt caaggctcgc
    21961 ttgtggatga tcgatcatat agattgtgcc atcgatcact tcagctaagt tatgagtcgg
    22021 gatttctgtt gcatatccag cagatatacc tgtcgatcca ttgacgagaa ggtttgggta
    22081 tcgagctgga aggactgttg gttctttttc tgtatcatca aaattccaca cgagatcgac
    22141 tgtttctttc tcgatatctg ctagcatctc tccacttaac ttggataatc tggcttcagt
    22201 ataacgcatc gcagcaggtg gatcaccgtc catactcccg ttattcccgt gcatttcgat
    22261 cagtacttcc cgcaacttcc agtcttggct catgcggacc atcgcttcat aaatactgat
    22321 gtcaccatga ggatgataat tccccatgat atttccgaca gattttgctg atttacggaa
    22381 tcctttgtca tacgtattgc catctttgtt catggcaaat aatatccggc gttgcactgg
    22441 cttcaatcca tcacggatat caggcagtgc acgttcttgg ataatatatt tggaataacg
    22501 tccgaagcgg tcacccatca cttcttctaa agttaattct tgtacttctt gtcgattttc
    22561 catcaggtga cctcctattc tacttcaaat aactgattgt tttcattttt atctgctcgt
    22621 tcttcatcta ataaatcatt agaaactgaa ggagagattt cagtatcctc ttttttatct
    22681 aagatactgc catcttcttc gagcgtaaat tgcacgtgat tttcgatcca ttttcttcga
    22741 ggttctactt tgtcacccat cagtgtggtt actcgacgtt cagcttgcgc agcatcatcg
    22801 atacggacgc ggatcaacgt acgggaagtc ggatccatcg ttgtttccca caattgttcc
    22861 gcattcatct ctccaagtcc tttatatcgc tgcagcatat atcctttgcc gactttttta
    22921 atcattgctg ccaattcgtc atctgtccac gcatattcaa tgacttgctt ctttccttgt
    22981 cctttggata ctttatataa aggcggtaac gcgatatata ctttcccagc ttcaatcagc
    23041 ggtttcatat aacgataaaa gaaagtaagc agtaatactt gaatatgggc gccgtctgta
    23101 tccgcatcgg tcatgatgat tactttgtcg taattacagt cttcgataga aaactcagga
    23161 ccgactcctg caccaatcgt atagatcatc gtattgattt cttcattttt caagatatct
    23221 tgcattttag ctttttcggt attgatgact tttcctcgta aaggtagaat tgcttggaac
    23281 tttctgtctc ttccttgttt agcagatccg ccagcagaat ccccttcgac taaatacaat
    23341 tcatttttct tagggtttcg ggattgtgcg ggtgtcaatt ttcctgaaag aagagattcg
    23401 ccttttttac gcttcttccc atttcggctt tcttctctgg ctttacgtgc tgcttctctc
    23461 gcttctctgg ctttgattgc tttacggacc aacatctggc tcatttcgct attttcctgc
    23521 aaataaaagc ccatttgttc actgatgacg ttatctacta cggtacgagc aactggcgta
    23581 ccaagttttt cttttgtttg cccttcaaat tgcagaagat tttcaggtac acggatagaa
    23641 agtacagcag ctaacccttc tctgaaatca ctaccttcca gattcttgtc ccgttctttc
    23701 agcaaaccaa cttttctcgc atattcatta taagatttcg tcatcgccgc tttcatacca
    23761 gcttcatggg ttcccccatc ttttgtccga acgttattga caaaagataa aacattttct
    23821 gaataaccgt cattgtattg ataagcgacc tctacttcga taccttcttt ttctcctgaa
    23881 aaataaacaa ctggtgtcaa tgtatctttt tcttcattca gataatcaac aaattctttg
    23941 attccttctt cgtaatgaaa aatttccttg actggttctt ctccacgaag atcagaaaga
    24001 gagattttaa cgccttttag aagaaaggca gattctctta accgttcggc taaaatttca
    24061 tatgaaaatt tcgttgtact gaatattgta tcatctggta aaaaatggac agtcgtcccg
    24121 tttgcttttt ttgtttttcc tatctttttc aaagtaccgt caggtttacc gccgttttta
    24181 aatttctgct gatactctac gccatctcta acgatcgtta caattagcca tttcgataag
    24241 gcatttacca cactggctcc tacaccgtgc agtccaccag aagttttgta ccctccttga
    24301 ccaaactttc cgccagcatg cagcacagta aaaatcactt caactgttgg tattccggaa
    24361 gcatgcattc ctacaggcat cccacgtccg ctatctgcaa cagttatact attgtcttca
    24421 tggatggtca catcaatctc actgccataa cctgataatg cttcgtcaac tgcattatcg
    24481 acgatttcat agactaaatg atgcaagcct cggctgtcag tggatccaat gtacatccct
    24541 ggtctttttc taactgcctc taatccttcc aatacttgga tggacgagtc attgtattcg
    24601 ttgtttactt tttttgccaa ggcaaacgct ccttcaataa tactttgcgg caaaaccgca
    24661 ccacgattat catactagaa aaggtcgtga aaaaaaagag ggtagacgag aaatcaattt
    24721 taattatctc ctaaccgctt tttcgacatt cccctctatc gatcatctct tctttgtggt
    24781 catttttatt tttggttttc tttcaactta ccaagttcaa tcttaataca acgatccatt
    24841 acgatatctg tacgtcctgc ttttcttagc atctcagctg cttctttgtt ttcaatccct
    24901 aattgtgccc agaacacttt agcatcagtt ttcaaaaaat cacctgctat ttcaggtaaa
    24961 aattcactcc gtctaaatac atctacgata tcgattggat catcgatttc tgtcaaattc
    25021 gcatagactt tctcgcctag aatttcttca ccagccaata atggatttac tggtatgatt
    25081 ttatatccat tgtcttgcaa tacctgtgca accatgtaac ttgttcgttc tggtttattg
    25141 ctcaagccta cgacggcaat attttttgct tcttccaaat agttgaaaat cgtttcttgt
    25201 gttggatttt ttacagacat ttctgccacc ccttgctttt ctttttattc catctattat
    25261 acttgtatct ttcatttttt caattgttcc tgttacctat tcatgctaaa ataaaggata
    25321 gttttcaact tgaaagaggg taaaaaatga aattgatctt attacttatt ttagcatatc
    25381 ttttaggttc tattccttcc ggtgtctgga ttggcaaatt gtttttcaaa aaagatatcc
    25441 gacaacacgg gagcggtaat actggaacga ccaatacatt tcgtgtatta ggcaaaacag
    25501 ccgggattgt tgtcctgctt atggatattt taaaaggtac attggctact tgtttgccga
    25561 tgatcttcca cctttctggg attaaccctc tttggtttgg ggtatgcgcc attcttggcc
    25621 atacatttcc gatttttgct gggttcaaag gaggaaaagc tgttgcgaca agtgcaggaa
    25681 tgcttttagg atttaatcct gtattttttg tttattcttg tatcatcttt atcgttagtt
    25741 tattttgtac aagtatggtg agtttgagca gtatgatcag tgcagtattg atcactttat
    25801 ctacgatcgt ccttccttat gtagctcctg tgattttggc taagcccaat tggttactga
    25861 cgatcattgc ctttttagtt tcttccttta tcttttatcg gcataaagac aatatcaagc
    25921 gtatcagaaa ccatactgaa agtcgaatcc cgtttggttt gaatagcagc aagaaaaaat
    25981 cctgatactt tttcattcca aagagataaa acgggagtgt gacaaatcga tgtcacactc
    26041 ccttattact tacaggatag cttttttaca caccttggta aacggtgttc cctgctaact
    26101 tctcggtcac aacctcttac ttcactgtga tggaatattt tgtcttgaag atttcatggg
    26161 cacctagttg attgatccct actttttcca tcaagtttcc actactgttc accgtgtcag
    26221 cgattccgca ccacggttcg atacaaacga aaggcgcttc ttttggataa ggagaccaga
    26281 tccctacata aggcatatct ttatagctta aagttacgct atgggaagat ttttcacttc
    26341 gaatggcgta cgcatttaga ccccttgttt caaaaaccaa ggcatcttgc tcaaaaagtt
    26401 cacgattcaa agccagattc gtatttgtct gacctaacgt cttttgatcc atatcgatga
    26461 atgggccttt caatggtagg cgtaatcttg atttcaatgg agaaaatgcc agatagaaat
    26521 cttcaaatga caatccttct tcaagaggta cattgaaagc aggatgtcca ccgatagaaa
    26581 agaacatttc tttttcaccg gtatttgcca cttgataatg aaccgtgatg ccgtctcctc
    26641 ctaattcata gctgatcact aattcaaaat caaatggata cttttctaat gtctccggcg
    26701 tactccttaa gatgaaacta gccatttctt gtccatgttc aatgacttca aaatccatat
    26761 cccgagcaaa tccgtgttgc cccatttgat atgttttccc ttgataaaca tactgatcat
    26821 cttttaaacg tccaacaaaa gggaataaaa ccggtgcatg tctgccccaa tacgctggat
    26881 caccttgcca gatatactct aaaccatgtt cttttgattt cagactgatc aattccgcac
    26941 cgtgttcagc gatttcggcg atcagctggt cattttgaat aataacagtc attgccattc
    27001 ctccaacttc gacttacttt ttaaaatggg aaggctggaa caaacatttc tatctgcccc
    27061 agtcccctta cttctaataa ctgtgttttg ctaactcgtc tttaaaacgg gaattcaata
    27121 cttttaaata agttcccttc atgcctaacg aacgagattc aatgattcca gctgattcca
    27181 attttcgtaa agcattgacg atcacagaac gagtgatgcc gatactatcg gcaatattag
    27241 aagcagtcag acgaccttca tctccatcca atgcttcaaa gatagcttgt acagccttca
    27301 attcgctata agataatgtg ttgattgcca tttggacagc cgttgcactc cgtacatctg
    27361 cttcgatgct tcgagacttc tgataaagga tctgcatacc gacaaccgta gctccatatt
    27421 ctgctaagac tagatcgtca tctgcaaacg attgttccat acgagataag ataatcgtac
    27481 ccaaacgttc gccagctcca aagatcggaa cgacagtcgt cagaccaaat ggatatttct
    27541 ctcttgactc taccggaaat gcagtaatat cactagtaat tgggatatta gcttcagttt
    27601 tcatcaactg tgccactgta tcagtataag attcaggaaa ttgtttctca acaaacattg
    27661 ttttgattcg ttcattgttc acatcgtgac gttcattata acctagtaat actccgtcac
    27721 ttcctatgat ataggtgttg ctgtcaagaa taccacctag tgtgacagcc attttatcgt
    27781 aaggcaaatc tgcttgcatg tcaaaagtat tcttttgctg caaaagtgtg tttatcttgc
    27841 gggttttcgt tagcaagtct gtcattgtcg tcctccgatt ttttataaaa tatagcgact
    27901 taaatcttca tttgccgcaa ttgagccaag tttgtcatcc acatatgctt ctgtgatcgt
    27961 tatttctccc atttgcatat ctggtgcttc aaataataga tcttctagta gtttttccaa
    28021 aatggtatgc agtctgcgtg cgccgatatt atctgtgtca cggttgacat cgaaagcgat
    28081 ttgagcgatc cgttcaattg cttcttttgt aaacgtaact gacacatttt ctgtaccgat
    28141 caacgcgacg tattgtttta ctaaagcatt atttggttcg gtcagaatct tcacaaaatc
    28201 ttcagctgtc aaatcatcta attctacccg tatcgggaag cgtccttgaa gttctggaat
    28261 tagatcactt ggtttagaca aatggaaagc tcctgaagca atgaatagga cgtgatctgt
    28321 ttggatgatc ccgtattttg tgtttacttg tgaaccttcg acaattggca atatgtctct
    28381 ttggacgcct tctctggata cttctccaga ttgctgtgat ttagaagtga tcttatcgat
    28441 ttcatcgata aaaataattc cactttcttc cgctaatttg attgcctcac tatggatatc
    28501 agcatccttg actaattttg ctgattcttc cttgatcaat aactctaaag cttctttgac
    28561 tgttaccgtc cgttccactt ttttcttcgg tgtcaaagca cctagagttt catttaggtc
    28621 gatccccatt tgctccaatc cattgttcat cattggtgca ggtttctttt ggtcttcaac
    28681 ttcaatggtt acttcacgac tatccagtaa acccttttgt agttgttcca agactgtacg
    28741 gcgattgatt cgaatatctt ctgtcacttc ttcttgcggt tcagcggtat tttgctgact
    28801 agcattaaaa agattcatca tttgttcaaa ttgattagtg gattgtttct gttctttttt
    28861 gataccaggt accaagattt ttaccaaacg tttttctgca ttttttttag cacttgtgta
    28921 tacacggctg tactgctctt tttctacgat ttggatcgca ttttctacta aatcccgaac
    28981 cattgattct acatctcttc cgacataacc gacttcagta aattttgttg cttcgacttt
    29041 gacaaatggt gcattgacga tttttgccaa acgtcgtgcg atttctgttt taccgacccc
    29101 tgtaggtccg atcatcagca tattttttgg tgtaatatct tgttgcattt tttcatctaa
    29161 ctgcaaacgg cgatagcggt tacgcaaagc aacggcaaca gatttttttg ctgcgtgctg
    29221 tcctacgata tattcatcta attcacttac gatttgtctt ggtgtttgtt ttaattcata
    29281 catatctact cacctcttac agttcttcta cgataatatt atgattagta aagatacaga
    29341 tatctgcggc aatatttaac gcattttctg caatttcttt cgcactcatg tcgttttgag
    29401 catagttttt cattgctcgg gctgcagcca acgcaaaatt ccctcctgat ccgatagcta
    29461 agataccatc atctggtgtg ataacttctc ctgtacctga aacaagaagc atttctttat
    29521 cattcattac gatcagcatc gcttcaagtt tttgcataga ttgctgtgtc cgccattctt
    29581 gagctaattc gacagctgcg cgttgtagat tcccgttata ttcgtttagt ttgccttcaa
    29641 atttttcttc taaagtaaac gcatctgcaa cacttccggc gaaacctaca acaacttctc
    29701 cattgtagat acgtcgtact ttctttgcag tgcctttcat gacaacagat tcacccattg
    29761 ttacttggcc atctccagcc atagcaaatt tcccgtcttt ttcgacggca cagatagtgg
    29821 ttgaatgaaa tggtgattcg accatgtttg tttcctccta aatttgttct tttccttatt
    29881 tttacgctct tggatggaaa gaacgatagt ttttttgtaa actttctttt gttacatggg
    29941 catagatctg ggtagtcgat aaattggcat gtcctagcaa ttcttggact gtccgcaaat
    30001 ctgccccatt atttaataaa tgagtagcaa atgtatggcg cagcatgtga ggatggatat
    30061 cactatccaa actgcttttt ttgatcattt gattcaagac atattcaatt ccagtaggcg
    30121 tgattggttt tccatgatga ttcacaaaaa cgatatcatg ctcttcgtga tattttgtca
    30181 tcaatacctg gcggccttcc ctgaaatatt cttgcagagc atcttgagca aaagaaccta
    30241 gaggagcata tctctctttg ttccctttac catggatcaa catgacctct gaatcaaaat
    30301 caatgtctga taccgacaaa ctgctacact cacttaaacg gatgcctgac ccgtaaagga
    30361 cttccagtaa agcgcggttc ctcaaatcca aaggactatc tcctgctacg ctgtcaaaaa
    30421 gtgcttgcat ttcattttca taaaaaaaac gtggcagtct caaatttttc tttttgagat
    30481 gaacgtaaga aaatggattt tcttttatca cttcttcttt gagaagatac tgataaaacg
    30541 aacgtaggct ggctatcttg cgactgatag aatttctgct atagctagga cgatgatcag
    30601 ctaatgcact caaatagaca cgaaccgtaa aatattccgc cttcagcaga tcagcgtctc
    30661 cagattcctc caaaaaatgt ttgaaatgga gaatgtcttc ttcatatgct tctttcgttt
    30721 tttctgaata tcctctttcg acaatcaaat aacgcaaaaa tttttgttcc cacgtggctt
    30781 ctgtcatttt ctcaccttcc ttttgtccca gagaataatt tagcacagcg tttataaaaa
    30841 gacaaataaa ttgtcagaat ttaaccaata tttctaagtt tgttcacaat tggcgcaatt
    30901 cctcacattt tgtttgagaa attcttaaga aaaacgcaag aaaaagagcg agactatccg
    30961 tctcaccctc ttcatggagt ttccttactc atttgggatt gcagtttttt ctaattctgt
    31021 ttttattgcc tcattagctt ttaaagctcg ttgtgcaatt gcttcatatc ttgctttttt
    31081 gtctcgaatg cgctctggca gttcaggaaa cagaccatag ttggcattca tcggttggaa
    31141 atgttttcct tccgcatgag taatgtagta agccatactt ccaatagctg tttcttgtgg
    31201 aaactcgact ggttccattt cttttgctaa gcgtgcggcg ttgattccag caagtagtcc
    31261 gctcgctgca ctttcaacat agccttctac accagtcatc tgacctgcaa agaacagatc
    31321 ttcgcgtttc gttgattggt aagtcggttt cagcaattct ggcgaattca taaagctgtt
    31381 tcggtgcatc acaccatagc gaacgaattc agcattttct aacccaggaa tcatccggaa
    31441 aacacgtttt tgctcgcccc atttcaagtg agtctgaaag cccacgatgt tgtataaaga
    31501 agctgcagca ttgtcttgac gcagctggat aacagcataa ggacgtttgc cagttttagg
    31561 atcttccaat ccaactggtt tcataggtcc gaaaagcatc gttttgaatc ctcgctgtgc
    31621 cattacttca attggcatac atccttcaaa atatttttct ttctcaaaag atttaagttc
    31681 tgccacttcg gcattgatta gtgcctcatg gaaagctttg aattcctctt ctgtcatcgg
    31741 acagttcaag taagctgctt ctcctttgtc atagcgggac ttcaaatata ctttatccat
    31801 atcgatcgta gctttgtcta cgattggtgc agctgcatca tagaaataaa aaccatctga
    31861 accattgaat gctttgatgc tttctgctaa tggatgagaa gtcaaaggtc ctgttgctac
    31921 tacggtgatt ccttccggta tttcagtaat ttcttcgttt atcactgtta ctaatggatg
    31981 ctctttgact tttcgggtaa ttgtttcaga aaaagaatcg cggtcaacag ctaaggcacc
    32041 accagctggc actgctgttt catctgccga agtgattact accgaattca atcggcgcat
    32101 ttcttctttc aataacccta ctgcattagc caaactgttt cctcttaatg aattggaaca
    32161 tactagttca gcaaaattac ttgtgtgatg cgcctcagtc gatttgactg gacgcatttc
    32221 atataaacgg acagggactc ctgcttgtgc gatctgccaa gcagcttcac ttccggcaag
    32281 ccctgctcca acaacattta ccattttcaa tgaaagaacc tcttttctat tatttttgga
    32341 tgtcttcttc gtaatctcca tttacacaga ctacttgttt accgcctttg actttcttct
    32401 cgaccagata tccgtcacat tttggacaat ttctgcccac tggtttatcc caagaagtga
    32461 attcacattc tgggaaacgg gaacaaccat agaatagtct gtttttctta gattttcgtt
    32521 caatgacttg tccttcatga catactgggc aagtcacacc gatttctttt acgattggtt
    32581 tcgtattccg acaatcagga aaattactgc aagcataaaa cttcccatat ttccctaatt
    32641 ttatcaccat cggatgtcca cagacatcac aatcgaatcc tgctggttca tctttgattt
    32701 gaattttttc gattttttct tccgcattcg tcagttcttt ttcaaacggt ttatagaaac
    32761 gatcaaccac tttgacccac gcttccgtgc cttcttcaat tttatccaaa tctccttcca
    32821 tttctgctgt gaaatggata tcgacgattt gagggaagaa ttcacagatt aatgaattga
    32881 caatttctcc tagttcagtc ggctcaaatc ttttttgtgt caattttaca tagtagcgtc
    32941 tttggatcgt atcaagtgtt ggtgcataag tggaaggtcg ccctaccccg ttttcttcta
    33001 gtgcacgaat caacgtagcc tcactaaaac gtgctggtgg ttgagtaaaa tgttgttttg
    33061 gttcaatatc aacagattgg actacatcgc cttcttcaag ttctggaaga atattttctt
    33121 tctcttcttt gccgtcatct ctaccttcca catacacttg catgaatcct ttgaatttga
    33181 tttttgaacc gttcgcaatg aagatgacac cattttgttc taatgtcact ttcattgtat
    33241 ctaaaatagc tggtgtcatc tgactagcca caaaacgtga ccagatcaat gtataaagtt
    33301 tcaattgatc tttatctaaa tattgtttga gttcatctgg tgtacgaagc acactcgttg
    33361 gacgcacagc ttcatgggca tcttgtgcgc cttgagcatt tttgatcttt cggtgatcat
    33421 gtctagaaaa ttcttttcca tacgtatctt caataaatgc tgcggcctct gcttttgctg
    33481 tatcggcaat ccgggtagaa tcagtacgca tgtatgtaat caagccgact gttccttgtt
    33541 tacccaaagt gattccttca tataattgct gtgctaccat catggttttt cttgttcgaa
    33601 agtttaactt acgggcagct tcttgttgca ggctacttgt agtgaaagga ttcgcagggt
    33661 ttcttttgcg ctctttcttt tctacttttt taacttcgaa gtctgttcca tcaattctag
    33721 cagtgacttc ttttacactt tgtgcatctg gtaatttctt tttcttaccg tcgattcccc
    33781 agaaatttgc tttgaatttc ttgcgagctt ttttaaaatt accgtcgatg ctccaatatt
    33841 cttctggaac aaattctcgg atctcttttt cacggtcaat aataattttt aaagcgacag
    33901 attggacacg tcctgcactt aaccctttct tgaccttacg ccagagaata ggactgatcg
    33961 aataaccaac gattctgtct aaggtacgac gagcttgctg tgcatctact aaatctacat
    34021 cgatcgttct tggttcctta aaagctgctt tgactgcgtc ttttgtgatt tcattgaaga
    34081 ccacccgatt tttttctttc agatccaacc caagtaggta cgctaaatgc caagcaatcg
    34141 cttctccttc tctatccggg tcacttgcca agtaaacttt ttgagctttt tttgctgcgg
    34201 ctttcaggct tttgatgaca tcgccttttc cgcgtataga aatataatgg ggttcataat
    34261 tgttttcaaa atcgataccc attttacttt tcggtaaatc tcttatatgg ccaacactgg
    34321 ccattacttt atagtttcgt ccaagatatt tctcaattgt cttggctttt gcaggtgatt
    34381 ctacaatcac taaatattta tacgccatta ctgaatggac tcctttccat tgtcgtgttc
    34441 ctactattaa aagaggattc atacaaatcg tagctaatca tatccattca gaaaacgttt
    34501 gtcaagaaaa gcaaatgaaa agtatggtgt tattctttaa attctgccaa gatatcttca
    34561 cccgaaaccg tgcaaactgc accgtcttgg atcaaatgat gacatccggt agaatgttct
    34621 gttaaaatat ttcctggaac agaaaaaact gttcttccaa gatccaatgc ttgctgtgct
    34681 gttatcagag agccgctttt tttcttggct tcaaagacac atgttccttt agacaaagct
    34741 gcgataatcc gatttctcat tggaaaacaa tgctttttcg ggccggattg aggaggatat
    34801 tcactcaaaa gaagatgatc atttgcaatc acctcttgca agtcacgatt ttcagcagga
    34861 tagacttgct ctatccctgt tccaatgact gcgattgtcc gtccaccatg agagattgct
    34921 gcttggtgac cgtatgtatc tatccctttc gcgcagccac tgacgatcac atatccagct
    34981 tctatcactg gttttagtaa ataataaact gtttttttgg ctaaagcaga agtgtgtctt
    35041 ccaccaacaa cgcttaacat gttacaagaa agtaaagata gatcaccatt ataaaacagt
    35101 acaattggcg gataggtcaa gtgaagcagc tgagggggat atttgggatc aaagcaagtg
    35161 ataaacgact gtttcgattg gattttgccc cagttagcgt gaatttcctg ccaacttttg
    35221 cgaaacagct cccggtgttt ggttatttta cctatcttaa tgatgtcttc aaatccgatt
    35281 tctttataag gatactgcat catccagtta gcaagtgccc attttccttg actactgatt
    35341 ccttttgtat aagcaagttt caataaattt tcttctattt gatacatcat aaaaccgcct
    35401 ttcgtctctc tttctaataa gatacgtaaa agcggctgtt ttttattgta aatatttttt
    35461 tacaggtgca aaacttttac gatggattgg cgtaattcct tgtcgttcaa gtccttctaa
    35521 gtgttccttt gttccataac ctgcattatg cgagaaacca tatccaggat aaagcacgtc
    35581 atattctttc atcaattggt ctcgatatac tttagcaatg atacttgcag cagcaatcga
    35641 cacagatcgt gcatcccctt tgattatttt ttcctgctga ataggcaaat ccaaggtcat
    35701 cgcatcgatc aacaaatagc ttggtacaat ggacaatttt tctactgctt ggatcatcgc
    35761 taatttactt gcttcataaa tattcacatc atcgattgtc tgctgatcaa cgatcccgat
    35821 cccgattgcc agggcttttt cttgaacttg ttgataaaga agttctcgct ttttctctga
    35881 taattgtttg gagtcattca gccctaatat gatctcattt ttcggcaaga taactgcagc
    35941 tgccacgaca ggtccagcta atggtcctct tcctacttca tcaatgccgg caatccattg
    36001 gtgaccttgt gcgtaccctt gcttttcaaa gcaaaacatt tcttcatatt tttccttaat
    36061 taatgcttcc tttttcaatc gtcgttcaaa agaagccagt gcttgctgca cgcctttgcg
    36121 tggatcattt cttaatgatt ctagtgtagg atcatctatt ctctgtatgc ttttcaatcg
    36181 ttctttgata ctttggatgg attcagtcat cacttttttg ctccatttct tcgcaacgat
    36241 ccagtgtgta tcgtccaagt tttccttgac gaatatcatg cacgactaat tcgctgccac
    36301 gatcatagtc ttctttatac ccacgttttg ctgtaatatc catcagtaat tccggtgcca
    36361 atttttcttc ttgctcgatt gataaaccat aacgatcgct gattcttcct gaataatatc
    36421 gggcaaaaaa gtctaatccg taaatcgcta aatcatctaa atggacaagc tggtctttga
    36481 tcgcgcctgt cagcgctagt tttttgccga tttcttcatc ttcaaatttg ggccataaaa
    36541 tccctggtgt gtctaacaat tccaactcat tacctaaacg aagccactgc tgaccttttg
    36601 ttacgccagg cttatttcct gtctgtgcaa ttttcttgcc tactagtcga ttcatcaacg
    36661 tagatttccc aacatttgga atacctaaga ccattgcccg aatagcgcga ggcttgatcc
    36721 cccgagcagc atctcttgcc cgtttttctt tcaatgcttc tttagccgca ggtactagac
    36781 ctttaattcc tttactttct tgtgccgtga tagctaatgc aagatggcct tgtttacgaa
    36841 aatattcttg ccacagcttt gtctgttgtg gatctgccag atccgcttta ttcaataaaa
    36901 caaggcgagg tttttgctga atgatctgat ctagcattgg attacgagaa gataaaggta
    36961 atcgtgcgtc taccaattca aatacgatgt ccacatattt cattttttca gaaacttctc
    37021 gtcgggcttt tgccatatgt cccggaaacc attggatggt cattgttctc tccattcctt
    37081 tcataccgga atattccccg gctttacttg tttttttctt tttcaatata aattcacttt
    37141 tttattataa agaaattcca tctattagtt aagtgaaagt gaaccagtcc tcattctatc
    37201 acatcttcac ttttttgatg atgcaaattt ttattttggt ttctatatat gaatctaaat
    37261 ttttgacagc gtttcctaaa taagagatga tagacgaaca aaacagaaag gagacgaaac
    37321 aaatgaatag tatggttttt gttaattttc ctgttgctga tgtcaatcgt tccgttgctt
    37381 tttatgaaaa gctgggtttt aaaaaaaatg aagaattttc tactgaagaa gctggttcaa
    37441 tggtatggga tgacactttt tggataatgc ttctctctca tgatttttat aaaaaattta
    37501 taaaagataa agaaatagct gataataaaa aaacaagtgg tgctttgatt tcgtttagtg
    37561 ttgaaaatgc ggatgaagta aaaaaatttg ctcaaattgc aaaagaaaat ggtggtactt
    37621 tccacgaagt agatatggga atgcctgaag aagaaatgtt ttcattagaa gtccaagatc
    37681 tagacggaaa tacattagaa cccgtatgga tgaagatgta agcagataac taatctgacg
    37741 ttttttataa caaaaaaaca aaggcggatg atacgataag tattctccgc ctctattttt
    37801 tttattcgta caatctcttt tttacagttt ataaaagcag tcttctcacc ctttttttaa
    37861 ttgttagatg ccagtgtatg taaatcacca atgtgtcatg acacattggt gattttatgg
    37921 tatcctttta ttattaactg acaaaggaga gaatattttg aacactttga ttgcaaaaga
    37981 cgtttttaga ttgcccgaaa tgaatgcaag attgttgtcg acctctgctc ttttattagc
    38041 ccttgatgtc atcttataca agatagcgat tggtcctgct tattttcaaa tcacattcgg
    38101 atttttaagt atggcgctta tgggttatct atatggaccg atctgggctg gtttgcttga
    38161 aatgttgtcg aacactttaa atttcacgat atttggttca ggaacgtttc aagctgcttt
    38221 tcttatcacg gctttccttg gtggatttat taatggctta tttttatatc ataaaaagat
    38281 aaacctgcct tccgtcatcg ctgcccaatt attgattatg atcccagtca gcctttttat
    38341 caattcttgg ctgatgtctg ttttgtttgg tgcagatttc aaagtaattt ttctaggtag
    38401 attcatcagg aatatgatcc aaatccctat tcaaataatg gttgtttatt catttatcaa
    38461 aactttagag gctagaaaag tgtttaaacg agctgtttga ttttacgtac taaggtagta
    38521 aactgatttt ggattaaaca ataaagcgtg cagtctcaac agactgcacg ctttattgtt
    38581 tctcactgga tccattttat ttcatcaagt ggataataga caaatcttgc tttacctaga
    38641 atatcagttt tattgatcgt gccaaacgaa cgactatctt ttgaaactct tcgattatct
    38701 ccaagtacaa aataattatc ttccggaagc ttggattgtc ccgttagctc ttgtagtgta
    38761 aagtccgtcg tataggatgc atttgcatga tctgatttca ggtttttagt tagataaggt
    38821 tccttaacta ctttcccatt gatcttcaat tgatcatttt ggtagctgac attttctcct
    38881 ggaagaccga ttactcgttt gatataaatc gtgccatctg ctaattgaaa aacaacaata
    38941 tcaaatcgtc tgatctccga aaatttttcc atcacaacca tatcaccttg cttcaacacg
    39001 ttttccattg aattgccttc cactggtacc gggatgaata aaaatccccg caacatgaac
    39061 gcaaggaata cagaaacaag taagtatttg aatacaagcc agaagcgatt aatatagcgt
    39121 tgtttttttg tcaatctcta tcaatccatc cctctttttt tcattctttc tttattataa
    39181 gaaaaatatc aaaaaaatgc gactagatag ctgaaataaa aataattctt tcaattaggc
    39241 tattggacaa aaaacttttt tgatcataaa gtacaaaact atctcttata tgtcatgatt
    39301 attttctaaa tatttttccc atgcttcgtc aaagatatcc atggacggca aatagtcgac
    39361 attcagttcc agataattag aaatttcttc gtagctagag ctgtgcttag gaaattggat
    39421 gtctttaccg gcttctgtag cgaaaacaga taaagcatca tgtgtgccac cgcctcgcag
    39481 tgtcattaaa taatgaaaaa agcttcgatt cacccttcgt tcctccaatt ttcttcgata
    39541 aaggcagccc ggcgtgcatg gtttctttta aaattttcag gatgcttttt ataatactct
    39601 tgatggtctt cttctgctag ataaaatggt tgggctggtt cgatttttgt aacgattggc
    39661 tgttcgaaac gtccactttc agctaactgt ttcttacttt tttcagcaat gatccgctgt
    39721 tcttctgtca aataaaagat caccgggcga taattgtcac cgcgatcctc gaattgtccg
    39781 aaagcgtcag ttggatcagt ttgctgccag taaagttcta ctaattgttc atatgaaatc
    39841 aatgttggat catagataat ctccactgct tctgtatgtc cagtcgtttg gctttttact
    39901 tgttcataag tcggatctgg tacatgccct ccagtatatc ctgacatcac tgtatggata
    39961 ccaggaagcg tgtcgaaagg ctggatcata caccagaagc agcctcctgc aaatattgct
    40021 cgttccatta tgattccccc tctaatacta ctcatccgat gattttttat tttcttttgt
    40081 cttgctttca gtactgctgg tgctagtttt gttggtattt gagttgtttg aagcatcaga
    40141 ggtatctttt ggcaaatata gactaaaccg aatgtcatca tttactaagt cgattttatc
    40201 tgctttaata tacatcccgt tttgcattcg gaattgatcc aacctaagca tgatagtcag
    40261 atcatctgta ttgacttcga tccaatctgg taatttatag tttctcttga tcatattcat
    40321 cacatctttg attggcaaac tcaatgttcc gatagaaaga cttctagctt ttagttggac
    40381 atttccgttt tccatcacat acggatcaaa atataaatag aaatcgatag gaaaacctag
    40441 tacttcgaaa gtaccattga gtagtgcttc attttccaaa taaaatttat attcaatatc
    40501 actatctttt tgatactcac taaggaaaaa gctgatgatt tgattgactt tttctttatt
    40561 tgaattgatc gttaagacag gatctccttg tctttccgta agagctggta tttctgggag
    40621 ttctggttcc cgattagcaa aaatacggct gcctaaaaat acggtcgaac caagtactac
    40681 cccaagaagg ataaggaagg cgaatttcca gtaatttgtt ttctttgttt tgtttgaaga
    40741 tacgtcagat cttgttttca tgtttattga tcatcctcct tctctaacca ttggttttgt
    40801 gtctcgatca gctgatctct cactgcattt gccatcaatt gataacctaa attatttgga
    40861 tggaaatgat cttcttcata gagcacatta tttttgatgc catttagatt ttctgtcgtg
    40921 ctagttgttt gatctgttcc ttcttctgtg acacctactt cctgattcaa tccttgataa
    40981 agcaaatcat tgattgggat aaagtagcag ttcggcattt tttttgtcac cgtttctgtt
    41041 cctttgttcc aattgttaac aattgtctgc atgtcagtga tctcaggaaa gttcaaataa
    41101 aatggattgt agatgcctaa aatgtaaata ggtgcggttt tattgaggga tcgaaattct
    41161 tccaatagtt ctgtgacatt ttcctgatag tttttcagtg gctttttaaa ggaattgacc
    41221 gttaacccga ataaattatt ttggataact ttcatcaaat cattaccgcc aacagtcagt
    41281 gtgataaaat cagctgtttt gatattgttt cgaatttctt cttttgtttt tactcgcttt
    41341 aagatctggt cacttcgttc accatttaca ccatagtttt ctgtttcaac cgcggtcaaa
    41401 ttataacggt cttttagatc atttgcgaca aggggaacga atcctccttg cttggtttga
    41461 tctcctactc cttcagtcag cgaatctccg atagctatgt agtgaagttt ttctttttta
    41521 tttggatctt ctctcacagt agttactggt ttcattagtg ggccagcttt cggtatagaa
    41581 gcagctaaac ctgcatagat gatgatcgca attaataatg ggaacaaaac gaggatcaaa
    41641 tgtcgtttcg ttaatttcat tttttcacct cttgtattcg attggttcta atgttatcaa
    41701 aaattttatc aaaaaggtag tctttatgaa aaaagaaaac aattattttc ctaattttat
    41761 aaagaaaaag agaataagct gcaagccttt caggctgagg gcttatcctc ttttcgacta
    41821 atctacataa tacatgattg caaacgcgtc tttaccagta tgcgtagcga taaccggatt
    41881 cgtatgcagt acagggatat gcatgtccgg gaataattct tgcaaaccct ctttgaattc
    41941 ttgcgccaat tcttttgcat ccgcatgtga aataccgatt tgtcgcacat ttggcaattc
    42001 tttcagttca tttttcaaat tattaaacca tttatcgaac gttttctttc ctcgcccctt
    42061 agttacaggg attaattcag aatgggcgaa attcatcacc acgcgtatgt tcaaaacact
    42121 agacagcaaa ccagttgttc ggctgattct tccacctttt accaagttat ctagtgtgga
    42181 tattccgatg tataattttg tattgtcttg tacttttttg acttcttcaa ggattttctc
    42241 tactgtttta ccttcttttg ctaattcagc tgctcgaatt acctgaaaag ataatccttg
    42301 gtcagtggta tcactgtcga taaccgttac tttcgttttt gttagattac tggcttgtct
    42361 tgctgcttct actgttccac tcaagccttt tgtcatatgg atcgaaatca cttcactgcc
    42421 gtcttctcct agctcatcat acatcgagat gaattctcca attggtggtt ggcttgtttt
    42481 gggcagattt tttgctttcg ccatcatttc cataaatctt tcgccgtcta gttggtcatc
    42541 atcgggatat actgttccgt cgatcatgat ggatagcggc atgacacgaa tgcctaaagc
    42601 atcgcgtaca tttttttcca tcgtacatga agaatctgtt acgattttta catttgtcat
    42661 tattttctct ctctctttct ttaacaagat gccttattca tgttaaacta catgtaagac
    42721 aatttctatt tttagtataa cagacaaata atgatttttc attaattaca cctagtaaag
    42781 gagccgtttt catggaaaaa acgaaattta atcgaacgta tgaaatatta aatgaagtgt
    42841 ttaatgcagt cacccatgga attgggactg gattgagtat cgcgggacta gtggttcttt
    42901 tagtaaaagg tgcccacttg cattcctccc tccatattgt ctcttatgct atctatggat
    42961 cgatgatgat tcttttattt ttaacgtcta ctttgtttca ttcattgatt tttacaaaag
    43021 caaaaaaggt gttccaagta ttcgatcata gttcgatttt tcttttgatt gcaggaagtt
    43081 atactccttt ttgtttgctg agtatccgag gatggctagg ttggacttta tttgtattaa
    43141 tctggttgtt tgcgattctt ggcattatat ataaagcgtt gacgttgcat aaacgggaga
    43201 gagtatcaaa agtatctacg atcatctata tttttatggg gtggctctgt gtcgtggctg
    43261 ctgttcctct ttatcactct cttggaatga ctggtgttat tttgatggta gcaggcgggc
    43321 tttcttacac gataggcgca ttcttttata gcttgaattc tatccgctat atgcatgttg
    43381 tttggcattt gtttgttatg ttaggtgcag gttttatgta cttctctgtt ttattcttta
    43441 cttaataaaa aaaataaagc tatggatggg acagctctaa ataacagcta gtctatccat
    43501 agctttttta tatcgtcaat tcgcctgtcc cgctttttac aggattctca ttacgctgat
    43561 acgtttcaaa ttgatgcgga taacgatttt tttcatccat ttctccttga ctagtattga
    43621 tcagtgacca atcagaccag tcaacaggtg gaaaataagc atctccatcg aatacatgat
    43681 ggatgactgt acggtataat atcgtacaaa atggcagaaa ttcttgataa acagctgacc
    43741 ctccagcgat gaaaaagata ccgtctgttt ctttttccag agcaagcacg tcttccacac
    43801 tatgcatgac atgcacgcct tctgctttat aggaagaatc tctcgtcaaa acaatcgtct
    43861 gacgattcgg caacggacgg ctacccatcc cttcgaatgt ttttcgtccc atcactagtg
    43921 tatttgcttc tgtcatttgt ttgaagaatt tcagatcatt tggcaaacgc caaggaagac
    43981 ggtcttcttt tccaatcaat ccgttttcat cctgtgccca aattgcagct aacattttct
    44041 catcctttct gattctaaac agcgatagga gctttgatcg ccggatgtgg gtcatatcct
    44101 tctaattgga tatcttccat ctcaaaatca aatactgact gcttttcctg attcaaaact
    44161 aaagtcggaa atgcgcgtat ttctcggctc aattgttctt tcatttgttc gatatgattg
    44221 atataaagat gagcatctcc taatgtgtga acaaattcgc caaccgctaa acctgtttca
    44281 tgtgcaatta ggtgagtcag caacgcataa cttgcaatgt tgaacggaac gcctagaaac
    44341 acatccccac tgcgttgata caattggcag cttagccgtc cctcttgaac ataaaattga
    44401 aacatcgtat gacaaggagg caaagccatg ctaggaacat cttccggatt ccatgcagaa
    44461 acgatcaatc ttctagaatc aggagtcttt ttgattgctt cgatcacttg tttgatttga
    44521 tcgataaagc caccgtcttt tgtttcccag tgacgccatt gatagccgta gatgtgtcca
    44581 agatcgccgt atgtttcagc aaaggaatca tcggttagga tcttctcgca aaaaagcttg
    44641 ctctgctttt tatattcttc attgaattca ggatctgtca aacatctatg gccaaaatca
    44701 gtcatatctg gtccattata gtctggactt ttgatgtagc gttcaaatgc ccattcatcc
    44761 caaatatggt ttttattttg taatagatag cggatattcg tatctccttt taaaaaccaa
    44821 agcaattcgc ttttgatcaa tccaaaaggt actcgtttcg ttgttaacaa aggaaaccct
    44881 ttttgcagat caaaccgcat ttggtatccg aataagctta atgtgcctgt gcctgttctg
    44941 tcttctttac gatgcccttc ttccaacaat tttcttccta agtcaagata cgcttgttcc
    45001 atcctttttc ctcctaatct tctacccatt cactcaagta ttcccaccgt gccatttttt
    45061 cttcaagttg tgcttctgtt tcagatacgt cgttttgcaa ttcttgtaat cgagtgaaat
    45121 tatctccttg atgattcatc tcttcttgga gcaatgagat tttttcttca agttctgcaa
    45181 tctcatcttc aatcgtttcc cattcttttt gttccatgta agataatttc ttcttttcag
    45241 caggttcctt gctctgtatt tttggtttcg ctttttcagc aggctgctgg gtctcttttt
    45301 gcttcagtaa ataactggac atgtttccgt aataaagttc ttgttttccg tttccttgga
    45361 atactaataa cttatctgct accttgtcca agaaataacg gtcatgggaa acagtgatca
    45421 cagcacctgg aaaacttcta aaataatctt ccaaaatcgt caatgttgct atgtccaaat
    45481 cattggtcgg ttcatccaat aataaaacat taggttgctg aatcagcagt ttcaacaaaa
    45541 ataaccggcg tttttctccg cctgaaagtt tgcctatcag tgtcccatgc ataaatcttg
    45601 gaaataaaaa tcgttcaagt aattctgcta ctccgatttg actgccatct gctgtttttg
    45661 cttcttcagc agcttcttgt aagtaagcaa tcatccgttt atctggtgcc atttcttcat
    45721 tttcttgtgt ataatacgca agatgaaccg tttcaccgat agacattgta ccgctatcca
    45781 ggggaattct gccagctaga atattaagca atgtcgattt tcccgcacca tttttaccag
    45841 taatacctag tctttcccga gattgaatca ataaatctaa atgttctagc agtgtttggt
    45901 catttatacg gtaactgcca tctttgattt ccagtacttt tttccctaaa cgttgtgtcg
    45961 ctaggttcag ctctaaatca tcttcttggt ttacttggta caagttctcc tttagatctt
    46021 cgaaacggtt gatccgtgct tgctgcttgg tgccacgtgc ctgtacgcca gccctcatcc
    46081 aagctaattc ctgtttataa agccgcttgc gcttttcttc ttgttctact tctacacgat
    46141 cacgttctgc tttttctaag acgtaagctt cataatttcc tttatactcg tataattttc
    46201 caaatgaaag ttcgaagatt cggtttgcta ctctatctag aaaataacga tcgtgggtaa
    46261 ccatcaatag tgcgccacgg tattgtttca aatagttttc caaccactcg atcgcttcat
    46321 aatctaaatg gtttgttggt tcgtctagta atagtaaatc gggttcatca atcaacactt
    46381 gcgccagact aactcgtttt ttctgaccac ctgataaagt actgattttt ttatctaatt
    46441 cactgattcc taatttttgc aaaataatct ttgcgttggt atctgtagtc caagcatctt
    46501 ctttattcat ttgttcttct gctttagcat aacgtttttg cacatcaggg tcttctccgt
    46561 tttcccctag ttcgatcaat gcttcctcat atgctcgaac agtttggatc aaggggctgt
    46621 ttccttgaaa gactgcttgg agaacagtta attcatcgga aaattcagct gcttgagaaa
    46681 gataaccaat acggtaatca gttggataaa acactgtttg ccgatcaccg tcgctgctat
    46741 cgataccggc aataatattt aagagacttg ttttacccgt cccgttcgtc ccaatcaacc
    46801 cgatacggtc tttttcgtgg accaaaaaag aaatctggtc aaacaaatct ttttcaccat
    46861 aagttttttt gaggtcagtt acttttaatt ctttcaacat gttccctcct tatcttggat
    46921 attgtatcat aaaaatagtg aacttcagga aaattttttt ggtatttgtt ctttttgtgt
    46981 tctcaaaaaa agaacaggac cgattcgatc ctgttctgat atgttttgtt ttttataaaa
    47041 cttgaaaatt tttacctttt tattttattg gactcgtttt ttttgacttt gctcgaaacg
    47101 caaatcggaa agaaaagtta tcagatggtt tgttcatcgt ataagattct aacaaattga
    47161 tattcctgcg atagctgttc gcagaaaacg tcgtgatttt ttcagcaact tcgtattcat
    47221 caatgatttt tctttcaaga taataacctc ttagcatttt tttcgtaaac agactatctt
    47281 gctggatcat ccacgaagaa atcaaattcc ccgagttcat ttttattcct tcaagtttgc
    47341 gttgctggat aaaaaattga accatcgttt catcataaat atcagtcaag ttatctaaac
    47401 tttcaataat caactgagta tttttttgat atgtctctct gatttcttgg atatcttcat
    47461 cactaataaa tgtctgacga tcagcatatc ttctttgcca aaacattttc ggatggagaa
    47521 cgattcgcat taacctacgg acaacaatga accaaaagcc gataaaagac aaaatctggc
    47581 ttgtgataga atgttcgaat cgagaaagaa aacgggagta aaaacgataa ccattagaag
    47641 aaagcttgcc cgaacgataa ctttcatcca atccatcccg ttcgatcgac aaaatcagtg
    47701 cttgtatttc ttgtacttct tgcttttcat catcggttaa atcttccaag tacagatcac
    47761 gtatccgttc ttgataattt tctatcactg cttcagtggc taaaaattct tttgtattac
    47821 gatcaatttc ctttatttct tttcgcaaaa cttcaacgac ctcttctaaa atcatcaaag
    47881 cattcaaatc cgtgcttttc gcttcctctg tttccgtcag cataggcaag acaatgatcc
    47941 ctatgaccaa agtcactaag atgacacccg ccgtcagaaa caaaagcaaa gaccgctggt
    48001 aaaacatcat attattgatt gaaaatggca aaataaaaat cgtagccaaa ctgactgttc
    48061 cctttacacc gccaaatgtt aagatcaaga tctcgttcaa ctgttttttg aactttttac
    48121 tgccatcttt gaatacataa aaaagactga tagaaatgaa tctgatcaca aaaagcatga
    48181 cagagattaa tacgataatc gctaataaaa gaccgtttgg atataaaccg tctccccata
    48241 ctggcgagaa cacttgcgtc aattcgattc ctaaaaatat aaatactaat gcattcagtg
    48301 taaaagcaat agttgtccat gtactgtggg acaagctcga caattctgca tcaaacacag
    48361 agattttcct aaaaccagaa gcttggagaa tacctgctgc cactgcagca atgattccag
    48421 atacatcaaa tgcctctgcc aatacatagg ctagaaaagg aagcaaaagt tcgatcagca
    48481 gataccctgt gacatcttgt gctgatgctt tttcgatcaa atgaattatt ttttgtttga
    48541 accagacaag caaaaagccg atcaaagctc ccccaatact agaaactact agactcatcc
    48601 ccgcgtttac tgctgaaaaa gatccggtga tcagcgcacc aagagcaaac tggaaggcag
    48661 taacaccaga tgcatcattc aaaagacctt ctccttccaa aatatgcatc gcctttttag
    48721 ggatattcac tcgtccagaa agagaactga ctgctaccgc atctgtcgga cctaacgctg
    48781 ctccaaaagc aaagcaggca gcaagtggga cacttggcaa caggaatgat aacgtcgcac
    48841 ctaccccgac aagggtcaaa atgactcctc caaatgccaa gaacaaaatt gtcccgaaat
    48901 ttttgagaat cgaagaaata tctgcttttt ctccttctct aaataacaat ggtgcaataa
    48961 tcataactaa gaacaattca ggttcaaaat cgattgattg tccccactct gtcagaccta
    49021 ataccactcc aaggaaaatt tggatcagtg gagctggaat cattggcaaa atgcggctag
    49081 ctatgttcga taaggtgatc gttactgcaa atacaataac taactcagca aattccatcg
    49141 tccatcccct ttatttttta ttttgtgtaa gcatttttaa aaattgttct tttttcttta
    49201 aaattttggt ttcgactact tcaacctgtg tttggttccc ctctaattca cactgtacac
    49261 gttttgactc caaacgaagc agatcatgtt tcagacgttc caactgacga tacatcaata
    49321 tatttctttt acgcaactta caaagtattt gacggcggtc atccatcgaa agggcgccat
    49381 agcgatcatg caacagtttt ttttgttgtt caaaactctc tctcattttc cagatctcct
    49441 atacacaaac ttccatcatt atagcaaagt tctttttgga tgaaaaatat ttcattgttt
    49501 catcgtttat tgctagttag aaatttccat aaatttttca acgcctcatt ctattccaaa
    49561 tagtatcaga tatcaagtaa aacttaagaa agataaaagt ttctgacaaa aggatgttta
    49621 ctttcccatt cctgcctttc ttgttctttt atcacaacaa aaaaatgggg ctgcgacaaa
    49681 aatcttgtca cagtccctta ttctgaataa acggtgtgga agagacagcc tatcagtagt
    49741 aataagacac atctctttca cagcctcatt tttgcgtaaa aatcgattta ttcgaaaaat
    49801 tccccgtata catcttctac acgttgatct ggattgatca cgatatacaa gttacctgtt
    49861 ttttcgctga tttttgttga ttgatattga ttgtctaatc cttctgttcc tttatctaga
    49921 tatgggaagt acacaagatc aggtgtgcca tttcggtaaa ggatttccat tcgctcgata
    49981 tcttcgtatt tcaatgcgcg attaaacatg cccatttcca gtccgcctag gttgatatca
    50041 tgtgtcgcaa ctgcgtcccc ttcatggaag atttcgattt taaatccagc acacggatgg
    50101 atttcaacaa attcactgcc attgattcgt ccaaaacttg ttgtgatttg tttgatccaa
    50161 agatcgccga tatgacggcg gttgatcgtc caggtttctc catttctaaa ataaaatttt
    50221 agcgctgtca tttctttact cattaaaaag actcctttat gatgtaattt attcttgtac
    50281 tacctcagtt tagcacaaat ttatgtaagt ggtcacatct tatgtttttt cttctaatga
    50341 cgtatctgcc cactttaagt agccaacaaa gctgagcaga tacagtctag tgttttttaa
    50401 atcaattttt ctttcgataa aaaatccaaa acctgttttt tatcattttt tattctttgt
    50461 tctacgacgg ctttttcagc taattgcaaa gcttcactaa cccacttacc aggttttttt
    50521 ccagtttctt ctagcaagat tttaccatct actgctaatt cgcttaatga cttgataggt
    50581 aaacgatcat aggattctcc tacggcatcc atctgaggtg tttcgtcaaa atagatcatc
    50641 aattcttcta cttgcagtgc atgttttttg cctaagaagt acaattcgaa tggttccaaa
    50701 gctccagttt ctcgttgtcg tagtccttgg acaagtgctt gaacgtcttt aatcatttgg
    50761 ttagaacact tccacgattt caaaaaggaa cgaatctcat tttcttttag atccagttgg
    50821 ctgatcaata atgcccatgc ttggctctct tctttcaatg ggacggatgg taattcagca
    50881 aaacgtaaaa gtgcttcgcc ttcttctttc aaaccgggac agcaaatgta gcactctgtt
    50941 tcaataaatg catggattcc cgcggcccgt tcatttccca agagcatctt gatgaattcc
    51001 acatttatac gttctacaga tattttacct aatagctcgt ggttttcttt gatggcgtag
    51061 aaggtttctt cctctaattt gaaccctagt tgactgacaa aacgcaaccc gcgcatcatt
    51121 cgtaaggcat cttcatggaa ccgctcatga ggattgccta cagctcgcaa gatctgttct
    51181 tctagatctt gcagaccatc gaacaaatcg atgatttctc catcttcttt caaagcaaac
    51241 gcattgatcg taaaatctct tcttttcaaa tcttctgcca acgaacgaac gaattcgaca
    51301 tgatctggtc tacggtagtc ctgataagtt gattccgtcc gaaatgtggt gatctcatat
    51361 tgttcatcat tttctaatac caacacagtt ccatgttcga tcccaatatc tatcgttttt
    51421 ggaaaaagct gtttgatttc ttctggaaat gcgcttgttg cgatatccac atcatggatt
    51481 ggctggttca gcaagatatc acgaacactt ccacctacaa aataagcttc atatcctgca
    51541 ttctctaatt ttttcagaac tggaattgcc ttttggtatt ccagaggtaa ttgttttaat
    51601 ttcatttttc caacctttcc tgcgtgtttc ttgtcctgag ataaagactc agttgcatgg
    51661 tgactgtttg acaagtccgt ttcagagtct tcaaggccag gaccacttca tcttgtttac
    51721 tcgtccttac gctcaaagcg attatggtct ctttgattga atttttccat gtttttttca
    51781 aaaacttcag ttaagtcgat attcaatgaa ttagccatga tcatcgtaac gaataaaaca
    51841 tcaccaagtt cttctgctac cgagttaact ggttcagaag cctttttgct tttttctcca
    51901 taagtgtggt tgacttctct tgccaattca cctacttctt cagttaatcg agccatctga
    51961 gctaatggag agaaataccc caccttgaat tgctggatat attcatccac ttcctgctgc
    52021 atactgtata aagaacgctt tttatccatc tttttccctc caaaactatc ttaccaaaac
    52081 tttaacgcaa atcctagata agagcaattg agaaaatcga atttccatgc tacatttagg
    52141 aaggaatttc taaatggaaa ttctgtgaaa atacataatt gaaagctgga attcatatgg
    52201 tcaaacgaaa aacagtaaaa gaagttcttt ttatcattat aggaacaagt atttatgcat
    52261 ttggtcttgt ttacttgaac atcgctaatc atttagcaga agggggagtc tcagggatca
    52321 ccttgatctt aagagcttta tttggtattg atccagctta tacgacttta ttaatcaaca
    52381 tcccattgat tttactagga ggaaagatcc tcggtaaacg ttccttggcc tatactgttc
    52441 taggtacact ttctttgtca ttctttttat ggatctggca aagggttcca ctagaaatca
    52501 atttacagca tgatctactg atcgtttctc tacttgcggg tttagttgca ggtgtaggaa
    52561 gcgggatcgt ctaccgcatg ggtggaacaa caggcggcag tgatattatc gctcggattt
    52621 tagaacaaaa ttacggcatc actatggggc gttccctatt ggcatttgat atcatcgtct
    52681 tacttgcttc attaacctat atcgacttga aacgtatgat gtatacgttg attgtttcgt
    52741 atgttttcag tcgtgtgatt gattcgatct tagatggcgg atattctgca aaaggtctac
    52801 ttgtcgtctc caacaaaagc gaagagattg caccactact gatgaccggt ctgcaaagag
    52861 gtgtgacttt cctttctgga gaaggcgcat tctctggtaa ttcaaaaaaa atcatctata
    52921 tggtcgttag ctctagtgaa ttaactgaag ctaagaggat cgtccacgag attgacgaaa
    52981 aagctttcct ttcaatcatc aatgtgcatg aagtggaagg gcaaggcttt acttatttga
    53041 agccacagac aagattactg aaaaaactat aagaaaaaag acaaagatag gctatgagga
    53101 aagattccac atccagctga cctttgtctt ttttagtact atactatttt taactaattg
    53161 ttatgttcac ttacccggtt acttttcttt tgtgtctgca aaaggatctt tcggttaact
    53221 tcatcagata atttcaaaaa agcatcccta tctccatctt ctagtgcttg atcgatttga
    53281 gcataaagca tttttagttt tgcctcttct tctttttctt gaaaatatcg ttcaattaat
    53341 tcagtatctt cttcactgac tgaagaatcc caagaagaaa atggattgtc ttctaagata
    53401 gatagatatt ctcttgtctg ccaagcattt tcgaatatac attccacata taaaggcttt
    53461 ttccaattca aacggatttc atgaaaaatc tggtctgtgt ccgtaaattc ttttccctgc
    53521 aaaaacaatt tcatgggttc cccttcaaca gatagatcac tgatctgcag tcctcgatcc
    53581 gcaaaattcg ccccttcaac aaagtggaca ttgcttaaaa tcgcttcatg attggcaaga
    53641 taattcaaga tccaaaaaac ttctcttcgg ctaaaagata catgattgac catccacgtt
    53701 aaaaaattct tcttttcccg tacatcaatt agcatttttc tcacctctct gttaggtcat
    53761 ctaataatga cagtgcctcc atatctcctg gttcaagtgt taaataataa gtcaataatt
    53821 cttgcgctct tttcagctgc ccttcttctc ttaagaaaaa ggcatactct ttcaagaaat
    53881 ctggttcatg tgatagttca tgataagcct gttcatagtg tacagctgca acggtaaagt
    53941 cttctaattc attataagca tgggctaggt tccattctgc ataaggatta gcagtttctt
    54001 ccatctgatt gatcacttgt atcacatctt catatctttc atcatccaag taaagattac
    54061 ttaaagtaag taatgtttca tcttgtttgt ctcctacttc taaagctttc agtaaaagtt
    54121 cttctgctcg ctgtctatca tgcagacgga aagcattttc cgaggccagg tgataaagtt
    54181 cgacttggta aggattttct ttgattcctt cttctaacac tgtttgtgct tcttcaatca
    54241 tttcttcttc ttgaagagct tgtcctagat atagatataa cgattgataa tgcggattaa
    54301 cttctcgaag ttcttccaga tagttgattg cctgctgatt ttctttcaat tgaagattcg
    54361 taaaagctag ctggaacagt cgatcatctg tcctttcttc tttcagtgct tcttctaaag
    54421 gtacgatagc tgcttcgaat tctccttgca tacttaagga ttgtcctaaa cgttcctgca
    54481 tcgagattcc tgaaatttca tttatcccgc ttgccaacaa tgtttcataa accactgctg
    54541 cctctttgaa acgatcaact gaaaaataca attcagctag cgcaaactgg atcaatggtt
    54601 catcaggaag caacccagct gcttctttca attttgcttc actcacttca gggattccga
    54661 taacttggta caaatcagct atcgccaata agctttgcgg atagtaatca ctttgcttat
    54721 ccactttttc caggtattca aaagctaagt cgatctcatt atcttcgatt gcaatttctg
    54781 ctaacgggat gttcagtccg tcattttctg ggtattggtt gatcagttgt tcaaaaatct
    54841 gttttgcttc gatcaaaaag ccaatagcca gcaattcttc gcctagttca gctaatatat
    54901 ctgctgggtc ttcttttaat gctttttcta aaaagatttg tgcttgtgac aagtcttcat
    54961 ctgataaagc ttgcaacatt ttttcgctat ttgtattcat ttcaattccc tcttatctca
    55021 ctgacgattt gttgaaatac cgtcattgtt ctcaataatt ctttttcgtt tggatgttgg
    55081 tatccgtcta ttatacctat tttttctaaa acaagtattt ttttgctttt ttctgccaaa
    55141 aaaagaactt tttccaaata ctccatcttt gaaatctgtt ccagccagtg gattggatag
    55201 ccaagcaagt ccagccacac aaaaaagttt tttagttgga aatcaaaagg atatgcttgg
    55261 agattccaca cgaaatgaaa catcattcct aaaaattttt tcatactagc agaaagtaga
    55321 tggccatttt cggtcagata aaaagcttgt tcaaacagtt taccataatt tgacaggttt
    55381 tctgcctcta attgataaaa atagatcatt tcttcgatca tcccggcaaa cggccgagtc
    55441 gttaattgct ttttatttgg atagttttta tacagatttt gcaaaaaacg atgatcacaa
    55501 atcattccgc aacagataaa agtcaaaaag tcaatctgct ttccgtccac ctgccgctcg
    55561 ctgattgttt gatcataaac gatgcgttct ggcagattga tggtttgcag cactacacga
    55621 tttggtagct gcaaaatcgt ccgctgcggt gttaatgctc ggcttagaga acggatcgat
    55681 acagggatca tccatagtga tgaatcaagg gttgtatgtt tttgaaaaaa acctgccaga
    55741 tccatgatcc cttcatttcc aaatccgatg ataaacatgg attgattttc gggatagcgt
    55801 ttgacgaaat caagcaggtt ctttaattct gttaaatgat tgcattgagt gttggcacaa
    55861 atataccagt cattgtttgc ttgatttgca aataacgggt tgatcttatc tgcaaacaaa
    55921 tcataatagc gctgattcgt taaaaataag attggctgat caatggaaag ttctcttagc
    55981 tgactgacta gcgtttctcc gtaaaacact ttcgtcaacg catcttctac ttgataatca
    56041 agttccatac gcatccctcc tcttcttatt tttattttac cattagtaag caaattctag
    56101 aaaagataag agcaaagctc acctcataac ttgcaaataa ataaaaatta aataaaatac
    56161 atgtgttttc tatgtatgac atacggattc ggaatctctg tctcttattt attccttttc
    56221 tgctaggaaa taaaaagaaa agcacttgta gccctagagc cacaagcgct ttttcaactg
    56281 tcttatttaa cagcgtcttt taatgcttta cctggtttga atgcaggtac tttgctagct
    56341 ggaatttcga tttcttcacc agtttgtggg ttacgacctt tgcgagctgc gcgttcgcga
    56401 acttcaaagt taccaaaacc gattaattga actttttcgc cgttagctaa agcatcttga
    56461 atagttgaaa atacagcatc tactgctgca gttgcatctt ttttagttaa atcagtagct
    56521 gaagcaactt tttcgattaa ttctgctttg tttgccatgg atagattcac ctcctccaca
    56581 agagatatga tagaaatatc atttagttaa aactttctga gtggtccaga agtttaaaaa
    56641 gaaatattga ttaacttcaa tattctgtta tcacgatatc atatgaaccg cttaatagca
    56701 aggtttttac caattttcac atgctttttt tagtcataga aacgtaacaa acgaaactgt
    56761 ctttttcttt tgaaaaaaaa acgtcgatat ggtaaaatgc ctattttctc ctacgaggga
    56821 taattcggat ggacgtccct tcaaaagtaa atgcttttct gatttgattt tctaagaaac
    56881 gttcataaga aaaatgcatc aattcctctt cattgacaaa aacgacaaat gtaggtggtt
    56941 tgacagcgac ttgtgtagca taaaaaatct tcaggcgttt tcctttatct gttggtgttg
    57001 gattgattgc tacagcatcc ataatgatat cattcaacac agccgaagag atacgaagat
    57061 tctggttcat acttacttgt tcgatcattt caggcagacg ttccaaccgt tgtttagtca
    57121 ctgcagaaac aaaaacgatt ggagcgtaat caagataccg gaattcatca cgaatctctt
    57181 gttcgaaatc acgcattgta ttggtttctt tctttacaag atcccattta ttcacgacga
    57241 taataattcc acgaccagct tcatgggcgt aacccgctac tcgcttgtct tgttcccgaa
    57301 tcccttcttc agcattcagt accatcaaaa cgatatcaga acggtcaatg gcacgcattg
    57361 cacgcatcac gctgtatttt tcagtatttt cgtatacttt tccgcgttta cgcataccag
    57421 ctgtatctat cattaagaat ttctgaccac tttcagaaac gaagtgggtg tcgattgcgt
    57481 ctcgggtcgt tccttcaata tccgaaacaa ttacacgttc ttctcctaaa atcgcattga
    57541 tcaaagagga tttaccaaca tttgggcgac caatcaaact aaacttaatc gtgtcgtcgt
    57601 cctcttcttc agtctcttca gagaaatact tcactgcttc atctaaaata tcaccaatcc
    57661 ctagtccatg gcttcctgaa acaggataag gatcgcctag ccctaaggaa taaaattcat
    57721 agatatcgtt tctcatttct ggattatcta ctttattgac tgctaaaatc actggtttat
    57781 tacttctgta taaaattttc gcaaccatct catctgcgtc tgtcacgcct tcgcgtccgc
    57841 tgactacaca aatgattaca tctgcttctt caatcgcgat ttctgcttga tgcttgatct
    57901 gatccataaa aggttcatcg ccaagatcaa ttccgcctgt gtcgatcacg ctgaattctc
    57961 gacctaacca ttcacctttt gcataaatac gatcacgagt tactccagga gtatcttcga
    58021 caatcgagat acgctcacca gcgatgcggt taaaaatcgt agacttaccg acgttcgggc
    58081 ggccaacgat tgcaattgtt ggatttgcca tattatttcc tcctcacaag tttccaatct
    58141 cacttagttt aacgaatgca ttgccaactt tcaagcatag attgtcaatt aaacgaagta
    58201 tttttattcc ttattgaaat actaatcgct tttcaaaaga aaaactgaga caaaagcagc
    58261 tgctttcatc tcagtcacag atacaaaatc aattattttt cagaatcatc ggttgctttt
    58321 tcttctactt cttctttcaa cgcatcacct aaaatgtctc ccatagtaaa tccagtattt
    58381 tcttctggta attcataaga ctcaacattt tttggttctt cttctgaagc tggtttttct
    58441 tctaaagctt tgatactcaa tgcaatacga tgttcttctg gatggatctc taatactttc
    58501 actttcactt cgtcaccttc atgaagcact tcatgtggtg tcgcaatatg tttatgtgaa
    58561 atttgagaga tatggactag cccttctact ccagggaaca cttcaacaaa ggcaccgaag
    58621 cttgtcaaac gtttaactgt tccgtctaat actgtgccaa ctggagcttt tgtatcgatt
    58681 tctgaccaag gtccaggctg tgtgtctttg attgacaagg aaacacgttc ttgttcagga
    58741 ttgatagaca acactttgac atttacatca tcattgacag ccaatacatc acttggtttt
    58801 gctacatgac tatgtgaaat ctctgagaca tggactagac cgtcaattcc gcctaggtcg
    58861 acaaatgcgc caaaatcagt aagacgtgca acacgtccac tgagaacatc tccctcatgg
    58921 atagttgaaa gaatttcttt tttcttttct tctctttcgt tttccactac cgctttatgc
    58981 gataagatca aacgattttc tgatggttcg atttcgatga ttttaaagct caatgttttg
    59041 cctttatagt ctgaaaagtc tgcaacaaaa tgatcttcca ccattgatgc agggacaaaa
    59101 ccacgtacac cgacgtcaac gactaaaccg cctttgacaa catttgtaac aggtgcttcg
    59161 atgaccttgc cctcttggaa atctctttcg atatcttccc aaactttttt agcatctaaa
    59221 cggcgttttg aaagtagata gctgccgttt tctttatctt tgccgatcgt actgataacg
    59281 actaaatcta atacatcacc gacttttact acttcgctga tatcttctac cggcaaagtt
    59341 gataattctt ttgccggaac gactccttca actccagccc cttcgattcc gacaatcact
    59401 tgtttgtctt caatgactaa aacttcgccc ttaacaacat cgccaacttt tacttcttgt
    59461 acgcttttca ttgcgtcttc cattgactgg ttgttctctt gattttgatc aaattctgtc
    59521 ataacacttg tcctcctaac caacattctg ccgtaagtac ggtactgttt ttagtttaat
    59581 tgattattca aaaaaaataa agcgatttcg ttcgttttcc ttgaaaaaac aattgttttt
    59641 catttttttt cttaatttaa aaaagaagat aacctttttt caaaacaaca gcttttattg
    59701 ctgcaacgac ttctggaatc gatttgccag tcgtatcgat acgaacagca tcctctgctt
    59761 gcttcagcgg agagacgtcc cttgttgaat cataatggtc tctttcctgt atctctttcg
    59821 tcagtgtttc aagatcagtc ggaattcctt tttcttggtt ctctttgaaa cgtctttctg
    59881 cacgctcact tacgcttgct actaaaaaga ttttcacttc tgcattcggt aatacagctg
    59941 tcccgatgtc tcttccgtcc atgacaacgc caccgcgttc ccctattttt cgttggacag
    60001 caactaattc ttctctgact tttccatgtg cagagacttc agaaacagct tttgtgacat
    60061 ctggttgacg gatttctaaa gtcacatctt ttgatgctat gaatacatgc tgtccatctt
    60121 cttgttgcga aaaagagata ggatactttt tgatcagcga aactagccct tcttcatctg
    60181 aaaaagatac attgttcgta atagctaaat aagttactgc gcgatacatg gcaccggtat
    60241 ctgtataaat ataattcaat tcttttgcta atatcttggc aacggtactt ttcccagatg
    60301 aagcaggccc gtcgattgca atactgattt gtgtcatgat ataactcctt tttctcagaa
    60361 aaaaagccgc aaagcgcggc tattattatt taattcttaa ttcttgacca gggtaaagca
    60421 taaagttgtt tggatctaag ccattcaatt caaacaattg atcagtggtg atccctgcac
    60481 gctcagccac ttgttttgga ccttcgcctg cttgaacagt cgttgttgaa ccggctgcag
    60541 ctgatgaaga aggtgttgtt tctgctgcat tgctgcttga atcccctgct tgataagttg
    60601 cctcacttga ggaagtcggt gttgtctctg ctgcaatact gctttctgac gttacacctg
    60661 tatcttgaga cacagtagat tcttccgcga ttgtactaga ttctactgtt gaagtctcag
    60721 ttgactcctc ttttgttgta cttgtagaac tttctactac tgatgtcgaa gtttcagaag
    60781 aagttgctgc tgttgcattg ttgcttgatc catttctgat ccagaaataa gcacctgctg
    60841 gaatagcgat acataagacc agtaaaatca aaaatagcga aagaaataat gtatttcctt
    60901 tcttttgttg tctctgagaa cttcttgatg aaacttcatc atctgtatcg tagattggtt
    60961 gttcccatgg ttcttgtgtt tcgttatttt ctgtagattg atgtctatct tttctgctca
    61021 ctgttttacc tcctaaactc tatcgtgtgt attataccat aggaaaaagt gtcttgtcct
    61081 aaaaaatcaa tgttccatgt tttttttaaa taaatttagt aaaatcgttc cccaatgaag
    61141 ttgttcagtc ttagaaaaaa gcttcctctt tggcagaagt tctgcttttg ctccatcaat
    61201 atcacaacaa ttctgcggct tttcggagag tttttcgcca aaataagcta agatgaattt
    61261 tctgcggcag ttttcttcat taatatagcg aagcatctgc tgcaggcgga attctttttc
    61321 tttttcctga cgtttgagcc gttccaccca attttctggt ttttcagact gctggatcag
    61381 ctccatccat tttttttgca gctcatcaaa gggagcttgc tctgtggcat attccaaata
    61441 aagctcaaaa ctttgtcgct gttctctaga aagttgatta aagaaataat ggatacgttc
    61501 atccccactt tgataaaaaa gaattgctgc actttcttcc tgatctctgc ctgctcgacc
    61561 gatttcttgt acatagtttt ctagactgtc tggcaaatca taatggacca cataacggat
    61621 atcagattta tcgatcccca taccaaatgc attcgtagca atgagaaact gcagctgatt
    61681 ttttacaaac tgctgttgaa gttgtcttct ttgagctgca tcaagaccac cgtgatagta
    61741 tccaactgta aaacgttccc tgaataaatg atacaatcgt tcgacttctt tttttgttgc
    61801 acaataaatg attgccgctc cttgtgctct ttccatgaag tgttcaagtt cttgttcttt
    61861 ttgctgcgtt ttccgaacaa aaagcgagat attttgccga ttgactgatt gtctgatctc
    61921 ttttggtggt cgatcaaata gtacatgacg tatatctctt gctactaaat ctgttgctgt
    61981 cgccgttagt gccagtgtga ccgggtttcc taaaagcttt cggatttttc ctaactgttg
    62041 atattctgga cggaaatcaa ctccccattg agacacgcaa tgagcctcat ctactacata
    62101 taacgcaata ttttgttttt tcagatgctc taaaagagaa ggattagtca acatttcggg
    62161 actcaaaaac aaaaatttat attgcgatag atgacggagg acgtatcttc tttcagattg
    62221 cgaaagtaaa ctattgaaag cagctactcg tttctcccct cgtttttgta attgcgtcac
    62281 ttgatcttcc attagagaaa gcagcggtga cacgatgatg accagacctt ccattaaata
    62341 ccccgtcaat tgatagcaaa ggctttttcc cgttcctgta ggcaaaatag cgagagtatc
    62401 ttctccatca agcaacgcct gaataatttc ttcttggccg ggacgaaatg aatcaaatcc
    62461 aaaatatttt tttaattcat ttattaacat tctgtatcgc ttcctttctc aatagataga
    62521 tttgatacaa acgaaattct ccataatcta attgtccatc tacattccat tcgctaaagc
    62581 gccactctcg cacggaatcc ttatttggtt ccaaacgttc gattgtttct gcagagagaa
    62641 tccactcgta tggaaaatca tcaaaaaaca aggcccactc aataagatga tctgttactg
    62701 ttcctctttt taaatgacgg attgccatga tctggtcaat tgtctgacca ttcataaaca
    62761 tctgcttggt gatcatcatg ctttgattga aattttgctg taataatgaa tcgatcaaag
    62821 cgtgccaaag cgaatctggc cgtttttcga tttgtgctaa caaaaggtgg atacatctgc
    62881 tttgttgcag ataaaccgct gactcatcat tgttttttgc cagctgataa ggaagcagcc
    62941 ctgttcgctc atttccagat aattggttag ctaaaaaatc tgctgcttct tctggtatct
    63001 ccgaaaacag ctgcaccaaa ctctcatacg cagtatcaat caaaatttca cgtggcaatt
    63061 ggctttcact aagccatttt tttagttgga aagtataaaa aggacttgtc tctgctggaa
    63121 gatagtcttg aatacccgtt gccagattag aaattacttg aacagcaaat ttaatgagcc
    63181 gccaactagt ttcccctgtt ctgccatagc ggtcaaaacg caaaccagta tgttctattt
    63241 gatgttcgga caacatatca gcccctgcag gcgttagctt tgcttcattt tcatttattt
    63301 cgatccaacc ttgctgcgca attttttgca aaatttgata aaacttatcc tgcttcaatt
    63361 ctggaaaact gttatggata aacaaaagtt cgtgggtaaa tccataaata agtactgaag
    63421 tcgttcgttt tcccacaagg agttggtaaa gagaactaat ccgcagcttg tgtcctgatg
    63481 aaaatagcga taaaataaaa acaatcatat tattctcctt aagttaggat ggttagaaat
    63541 gtcactacta tgtaaacttg tacctgaacg ctgtattgca tgcggtcttt gtcaaatcga
    63601 agcgccagat attttcgatt atgatgaaga aggaatcgtt ttatttgccc aagaaccaga
    63661 ggctcatcaa cagttcgtga tgccggaaga agaaacatat gtaaaaaaag cgtatcaaaa
    63721 atgtccagtt cgagcgattt tattagaaaa taaaatataa atataaacga aactttaaaa
    63781 acgtacacta agttctctaa acttgaaaat aagccgggat ctgtttctct tgttccgtga
    63841 aatcccgact tattttgaaa gattcatttg ctatctatag ttaattgact agttttttca
    63901 cggaccctat aggacccatt tatattattt caactttttc agccagtttt ccaatgtatt
    63961 gacgatcaca gtttgctggt ctgcgttaga aatttctgcc tctccatctc ctttttgctc
    64021 accatagctg ccaaaacctc catgatttcc gccattgatt gatacatact ctgttctttc
    64081 cggtaaatac tgcttagctt cttgataagc ttcctgattc aatactttat cttttgtcgc
    64141 cgtgatcgat aaaacaggaa cagctgattc tgtcaatgtt ccttttttgt cgggataact
    64201 tgccatgaag aatacccctt ttaaatgttt gtctgaatga ttcttattga cataacgact
    64261 tgccattacg ccacctaatg aatggccacc gatcacataa tcggaatttg gaaaatcttc
    64321 tttgacctta tccgctttgt ttccgcccat cactgctaga tcaagtggca ttttgacaat
    64381 agcgactgaa aagccgtttt ttgctaaatc ttgcgcccaa atactataac tttctggctc
    64441 tacgagagca ccaggataaa aaataagtaa tggagacttt ccatgattct ttttctctcc
    64501 ttcaaaaaat aagtaatctt ctttgttttt tccttctttt accaacactt gcgcttctga
    64561 cgatggttcg tacgtatttt gctgtatata gtaataaccg gctccaccga gtaatcctaa
    64621 aatgatgact aagccaatta gtattcgtct aaatattttc actttctccc accttttcta
    64681 tctgagtgac ccctttttct taatcaagta tgattatacc ttaaaaaaat aagagagaaa
    64741 tgcaaacttt ccagcatcaa ataaaaaaag acggaatatc catttgaata tccgcccttt
    64801 ttgtatgttt atttttattt agcacataaa cgatacacag cttctgcata aatttccatt
    64861 gctttataca tactacttaa ttcccatcgt tcattcgcct ggtgcataaa gtcaggagta
    64921 tcagggaaca tcgcaccgaa tgccacacac tggttcatcg tacgagcaaa agtagcgccg
    64981 cctgatacaa acggttcagt catgtctcca gtaatatcgc gatatgtccc caatagattt
    65041 ttcactaact cactgtctag tggcacgtat aatgaatcaa ggaagtcaaa ttcttcataa
    65101 gtcaacccat atttttctgc tgttttagtt aatttagcta ctaaatcatc tttcttgaat
    65161 gtaacaggga ttctcatatc tacaccgatt tttgtttgtt ctggtgtgat ttccaaactt
    65221 gcaaagttca tcgttagctc gccggattgt tcatcttctg ttttgcccac gacagcttca
    65281 ccagttgcat tttcttgaac taattttcct aagaaattga ttgggccaaa atcaaatact
    65341 tctgaaagag caattgccag acgagaaata gcattcactc cttgtgctgc atctttcgcg
    65401 tggatacttt taccaagaac gacgatgcct tcaccttgtt cttcgaaatc gaattcgtgt
    65461 tttttcaatg cttcttttac ttcagaaagc ttttctccag agtaaggagc tgcatcagga
    65521 acaacattca acgctcctcc agcttttaca gaaaactcgt tcgttcctgg tcctgtcaag
    65581 taagcttgca ataagccttt ttctgcataa attaaaggaa attcagcatc tggcgcaaat
    65641 ccttgcgtaa ttccttcttc tttttcgtta tatttttcta aacaacgcca taaattttct
    65701 tcatctgtac caaagataaa acgaatacgt gtcttgaatt ccacgccagc atcaatcaaa
    65761 gctttgacgg catacattgc cgcaatagaa ggacctttgt catcttggga tccgcgacca
    65821 actaaccagc cgtcttttat agttggatcg aatggttttg tttcccaatt attttcgtcc
    65881 cctgctggaa caacgtccat atgacacaag ataccgaata attcatctcc agagccaatc
    65941 tctgaataac cgtaatagcc ttctggatct ttaaatgttc taaatcctag cttttcactg
    66001 atttccaata ctttatccaa agcttcaatc acttttttac cgaagggatg tccttgtcct
    66061 gaatctgctt catctagtac ggaaggaatt cggatcaatt cgctcaatga ttctaatgct
    66121 tgttcatgat gttgttctgt cacaaatttt ttcatgatat tatcctccta atatgttaaa
    66181 aagggtcatg tcaaattcct ccgacacaac ctcttcttct caaataatga cgttttaagc
    66241 ctgctccatc agcaagcaga atgttcttaa caaatgatga aagaaaaaac actcactgaa
    66301 tggagctatt gacttatcca cgtgcttatc gatagccgtt tatcggtttc ttcattctta
    66361 tgatagacct tgtacctgta tttgtctagg tttagaacat tgctgctaca cctaggatca
    66421 cacagatggc tacaaataat atcgcaatta atttaccggt aaatttccac cacactgaaa
    66481 catcgaaacg agcaattgct acagcaccca ttacgatagc agatgttggt gtaattaagt
    66541 ttactaaacc agatgcagat tgataagcag tgattactaa atccttaccg acgccggcaa
    66601 attcacccat aggtcccatg attcccattg ttgcagcagc taagccggaa gttgaaggaa
    66661 tcaagaatga catagggata tagaaaataa atgtaataat gatgaataca cttgaagata
    66721 atgaacttaa tccttgttcg ccccaatgta agatggtgtc tgtgattaat ccattgttca
    66781 taaccacttg gataccacga gcaacagcta ctacgattgc tacaccgatc aaatcagaag
    66841 caccagctaa aaattcagag acaaattcag actctttcat gccataagtg attgctacta
    66901 cgatggacat tactaagaat aacatagtaa tttctgggaa gtaccagtca cctaatggaa
    66961 gcatgctttt acctagaacc gtacctagta ccggaaggtt tgttaaccag tttgtcaatg
    67021 attcaaaaat cgtgaaattc gcattcaagg ttgtccaagg aatcaaactg atgatcatga
    67081 taccaaaagt aataaagaac aatacattaa catgtttttg ttttttcgtg attacttctt
    67141 gacgaccgat tgcttcaata tcgaaatgct tcatatcttc tttacgttgg ttgtatacta
    67201 atgattttgt tggatctttt tcgatctttg atgcataacg atacacatat acaatagaaa
    67261 tagctaacaa aataacgaac atcaagaatc gaagaccaat accttcaccc atcgaaatcc
    67321 caacagcttg tgaagctacg cctgttgcaa aaggatttac cgttgaagct agacagccta
    67381 cttgagaccc tactaatacg attgctacag ctactactgt atcaaagcct acagccatca
    67441 tgactgggat cagtaaagca tagaatggaa tcgtttcttc tgccattccg taagtagagc
    67501 cgcctaatgc aaataacagc atcaatactg gaataagcat tttttctttt cctttgaatt
    67561 tcttcacaac tgaagcaatc ccggcatcta gtgcccctgt tttgttgata atacctaaaa
    67621 atccaccaac aaccaaaatg aagaaagaga ttgggattgc agcaggtgtt tctttagtta
    67681 gctcccccgc tggtacacct agcatcccat tgattggcgc catgaaaata tcccacagcc
    67741 cttgaggatt ttgttgtact cgttcatatg atccagcgac gatgttgcct gcatcgtcta
    67801 cactatagtg cccagctggt ataaaccaag taagtacagc gattactgca ataataataa
    67861 ataagaccgt atacgctgaa ggcatttgaa attttttctt ttttgtttgt tccatcttct
    67921 tcttcctttc ttttccgtta gagacaacaa ttttggctct aatgttattt tatcaaaaag
    67981 agtatcagaa caaaaataat aacacgcatt ttgtaaaact tttgttcaaa aagttcgttt
    68041 ttccctattc cctcctcttt tttcaggttt ttaaagcttt cttctttttc attgtagcgt
    68101 ttcctttttt tataaacaaa cattttcgtc ttttaaaagg agaagaattt cacatttgca
    68161 aagaattgat tgatttttat gcataaatca aaaaaatact caaaacaaac aaataaaacg
    68221 tttacattat tgcatgtctt gtattttttt ccaaaaaaaa agaccaagaa atttcttgat
    68281 ctttttgata tttatttgac tgctgtatga cgttgttcga actgatgttg ttttcgactt
    68341 aaccatggaa gaagttgcgc atgcagcact aaaaagacag cactcacgat gaatcctttg
    68401 atcaagttga aaggaacgat cccaatcagt acatagtttg ctaaagacat gcccagcatc
    68461 tgtgttgcgt tcagccctaa aaacattaag taaagaggcg taataacgaa ataatttgcg
    68521 atactcataa aaatagttag agcgatggtt cctgtaatga cacctaaaaa tttgtttctt
    68581 cctttatgct gtttctttac actaaagaaa taataaatcg ggaatgtaaa gatcgttgtt
    68641 gataagaaac tagcagtgtc tcctaccaaa ttatccggag aaaaacctgt agtcagcaga
    68701 tgtaatactg aacgcaagaa cgctgttgca actccggccg ctggaccgaa taagaacatg
    68761 ctgatcaata ccgagatatc actaaaatcg atcttcaaaa aactaaaagc cggcatgatc
    68821 ggaaaagcaa aatactgtaa aactaatgcg atcgcagcaa acatcgctac tgcaaccatt
    68881 ttctgtacac gggtgttctt catttgaaat cctcctgtta ggactcctct tcagcgaact
    68941 ttttgacgtt tctctccaaa tgaaaaaact ctattttcca gggaaaatag agttagagtt
    69001 atttgatcaa gcgtcgtcaa ataagctcta tcttctttat ccagactata ctgtcggtat
    69061 cggaatttca ccgattcagc tatttttttg caaaataggt cgtggactat aaccaccggt
    69121 cgggaatttc accctgcccc tgaagacgaa ccttatataa tttttgttta catattcatt
    69181 atacatatct attcaaaaaa cgcaacatct aacacttata aaaagtaagt gttcattttg
    69241 agtggttcag caaactgctg acttcttttt tgttcagttc acggtaatcc ccaggacgta
    69301 ggccttgtaa agtcagatct ccgtattttt cacgttttag tttttgcaca ggaagaccaa
    69361 ctgcttgaag catatttttc acttgatgat tacgtccttc gtggatcgtc aattccacga
    69421 tactgtggtt tgtcttagga tccactgata aaatttggaa tttagctgga gatgtttttc
    69481 gtccttcgat ctttattcct tttgtcaaag gtgcaagcat cgattttgta gcgatccctt
    69541 ttacctttgc aacgtaaact ttatccactt catgttttgg atgtgtcagg cgctgagcaa
    69601 aatctccatc atttgtcagt agcaagatcc ccgaagtatc gtaatccagt cgacctacag
    69661 gatagatacg ttcttttacc atcggcaaaa gatccgtaac aacttttctt cctttgtcat
    69721 ctgcaacagc agaaataact cctttaggtt tgtacaataa atagtaaccg tattcttctt
    69781 gataaattgg gacttcatcc acttccacag tgtcatgttt cccaactttt atccctaatt
    69841 cccttacaac ttgtccgttt acttttacac gtcctgcaag gatgaattct tctgcttttc
    69901 gacgagaagt gatgccagcg tgggcaatta ctttctgcaa tctctccatt acaattattc
    69961 tcctttattc attccatcaa agaatagatc tggtgacacg tcttcttcaa gtgaaatttc
    70021 catttcttgt gtatcaggca gttcttctaa tgatttcaaa ccaaaataat ctaagaagta
    70081 gccagttgtt ccatataata tcggccgacc tggtccttct actctacctt tttcttcaat
    70141 cagtttatgg gcagctagac gctgtaccgc tcctgaaacc tgaactcctc gaatctgctc
    70201 gatttcagct cttgtgattg gctgtttata agcgatgatt gctaaggttt cgacggcggc
    70261 ttgagataat gtgtttgatg tcccttgcgc atatcgctta agtaagggag ccagctcttt
    70321 tttagtcgtt aatacataat ggctttccgt ttcaaaaata tgcaaagctg agtgcgagtt
    70381 ttgagtgtaa gattctttta attctttcac taaacttgtg acttctgctt cgctgagatt
    70441 taacagtccg cttaattctt cattactgat cccttcctcg ccaacaataa aaagaagggc
    70501 ttcaagttca cttaatttcg tcatgttcgg tatctcctac tgctggataa agcataattg
    70561 attcatagtt ttctttttgt tgcgcaatga tctgcccttt tttcatcaat tctagcaaag
    70621 ccataaaagt agtgacaact tcacttttag aaggtgactc aaaaaaagaa tcgaaagtac
    70681 agccatgcgc atttcttttt atacgctctt cgataaatac cattcgttct tcgatcgttg
    70741 tgtcatcggg cgtgatcgtt ttttccactt tttgagaaaa tttcttacgt tctaagattt
    70801 tctgcatggc acggatcaaa tcgatttttt tgacttgtcc tcgcttcaac ggcttttcag
    70861 catccgctaa cccatcgatg ttcataggtt cttttgtgta ataaagactt cgttcctctg
    70921 ctttttctgt cagtctttca gctgcatatt tatatttacg gtattctaaa agctgagtga
    70981 ccaattcttc tcgaggatct tcttcccata attcttcatc gtctgtgacg aattcttgga
    71041 caggaagcaa tgtcttgctt ttgattgcca tcaatgtagc agccatcact aagtattctc
    71101 ctgcaacagc tagctcgagt gttttcattg tatggatata attcatatat tgctccgtga
    71161 tcgtagcgat cggtatatca tatatatcga tttccatttg ctgaatcaga tgaagcagca
    71221 gatcgagagg accctcgaat acatctaatt taatattgat ctccgtcaac tcattcactc
    71281 tttcttcttt ttctttgcta gccattttcc aatgtaaggc tctgtgattt cagttgcacg
    71341 gatggagaca tccgggtact tttcctgtaa ttcatctaac atttgaaagc ccatattctc
    71401 accgcgataa gacggattca aagaaatgtc atggatgatc agctgatcgt tcgttgccca
    71461 gtaaatacca ataatccctt gaatgttggt tgaaccttct ggcgtaaaga aaaaaagttc
    71521 ataatcgtct tcagattcgt acgtatcaat ctccttcaac aaagaagttt tacctgtcag
    71581 tttcttatgg aaactcaata gtcccatagc aattttacgg ttttctttcc ggtaatgtgt
    71641 taacatcttc tcaccttcct atgactaagc ccttggaaaa tgctgcttat aaacatccgt
    71701 cattcttttc ttcgtgatat gtgtataaat ctgagtcgta gagatatccg cgtgacctaa
    71761 caattcctgt actgtccgca aatcagctcc attttctagc agatgtgtgg caaagctatg
    71821 ccgcagcgta tgtggtgtta cttctttgta aatcccagcc tctcgtacta actgcttcag
    71881 atttttccag attccttgcc gagaaagacc tttcccatga ttattgacaa atacatgcat
    71941 ttcagatgcg tcctttacaa gtaatggacg tgcttcgtct aagtagcgtt ccagccattg
    72001 gatcgcataa tcacctaaag gaatgatccg ctctttatct ccttttccaa ctgtctgtac
    72061 cagtccaaga gaaagatgaa gatctcccaa tttcaatcca atcaattcac tgacgcgcat
    72121 cccagtagca tacatgactt ccaagattgc acgatctctt atccctaacg tttttgtcgt
    72181 atcaggtgct tcaatcagct tttctacttc tgtcagagtc aatgtacttg gtaatttctg
    72241 tgctttcttc ggcgtatcga tatgttgcat cggatcatga tcagtgatac gctcttgccg
    72301 taaaaactga tggaatcttc tgagacttga gatcatccga gtaacagttg ctgtcgcttt
    72361 tttttcttca tgcaacttct ccagaaaacg gatgactaaa aagcgatcga catcctgcca
    72421 tgaagcaatt ttctgctcct gtagaaaatg caagtactgt tccaaatcac gttcatagct
    72481 ttgtcgtgta ttggcggaca atccccgttc aatattcaag tagtggagat aatcgttgat
    72541 ttgctctttc ataataatcc ccctcatgcc tctctatcat atcagatacc gcttcattct
    72601 gatagtcttt ttccataatc tgagcaaaga aaaagccgtc tagacactca gacggactgg
    72661 tttctttttt ctttttcata gcattcctga cagattccat ggaacgttag ccgatgatct
    72721 tttactaaaa aatgataacg ttcttctact acttgctcca cttcaagtaa aagatcctct
    72781 tctacttcct cgatcgtgcc gcagttcaag catagtaaat gatgatggaa atgtttggcg
    72841 ccttcttttc tcaaatcata acgggctaat ccatcattaa aacttacttt atcgacaatt
    72901 ttcaattctg tcaagatttc aagggttcga taaacagtag caagtccaat ttccggactc
    72961 ttttttttca ctaaaaagaa gatttcttct gcagataaat gctctttctc attttccaaa
    73021 agcacaagca gagtagcttc tctttgcggt gtcagcttaa accccgcttc atgtagctgc
    73081 tgttttgttt ttttcatcgc cgaaatagca ttcatgacca tttactcaac cccaacaatt
    73141 tataataatt acaaataaaa aaagatataa cactatgtta attaaaatta ttataagcta
    73201 gttaagaaaa acatgcaagg gattctcaat tagatttttt gactagtttt gtcacaccgt
    73261 tttcttgtgt aatcaatcct tgtttcaaaa gattacctaa tgcgcgctta aatgctcctt
    73321 tgctgatacc aaaagctttc atgatttctt ctggatccga tttatctgta aagttgattt
    73381 gctgatctgc agaacgttct aaaatggtta aaatcatttg tgcatcatct gatatagctt
    73441 catatgctct tggcttcaat gaaagattca gtacaccgtc tggtcggaca ccaatcactc
    73501 gaccttttat ctgctcgcct agacgaggtt cattatatcg ttcagaagga tggataaacc
    73561 caagatagaa atcttccgtt aaaacgtacg tacctgttaa tttcaagcgg tatgctgttc
    73621 ctatcacatc tttgtttttc atttcttctg ttccatattt gcttaaagat ttgaatattt
    73681 tttcatctgc taaactgccc caaatacggt cttttgcatc aactctaagg gaaatcatca
    73741 agcgatcccc ttttttaggc catagctctg tcattgtcgg caattcatca agagatacga
    73801 caaagtcttt atctggaaga ccgatatcga caaacgcacc taaatctttt cgtgtagcag
    73861 taacgattcc aaaagcgtaa tgaccgatac ggcttttagg aatttgtgta gtgatccgat
    73921 tttcatgttt ttgattttgg taaccgaatc cttcaactgc ttcaccgatt ttgtgttcac
    73981 cttctgattt gcttaagcca aaggtttgtc cgtttttttg gacaaagtag tttttttcat
    74041 tttcatcaat aataatacct gtaaatatag ttgctaataa atcgttcatt tttttctccc
    74101 tctatagtga aaggttttct taatacattt ctttgctatc ataacataat gttatctact
    74161 tgaatagctg agccttggtt tggaaaggtg aaaaaaggag tatgacaaca gttgtgtcat
    74221 actccccttt ttcgaataaa cggtgttaaa cggcaggctc acagcctctt tcatttgcct
    74281 aaaattaatt gctcccattt cctccgaacc atccagtttt acagttgatg gttacgatgt
    74341 aaaatggcaa agcactttct ccaatgcctt tcatcaatgc agattttgtt gaagtggcat
    74401 atagattata atagccttcc ccattttcga ttctggcttt ttctaatctg taacctcctt
    74461 caacgatata tccacgttgg atacatgtag caatcacttt gctttggaca cctggtgccc
    74521 acgtccatgc tggattagat gcatcggcaa tatcacttgc tctggcagat ttgattggct
    74581 gattcgctga gtttgaagag gaaggggtcg aggatgccgc ttcttgctgt gctgcttgtg
    74641 cgaccgcagc ttgttgagcg gcttgagctg cagctgctgc ttgagcggct tgttttgctt
    74701 gttcttcagc tgcttttttc gcttcttctg cttttttctt ttcctcttct tcttttttct
    74761 ctttatcagt gagcatctta tctacttgtt tcaattgttc attcaactga gcagatagat
    74821 ctgtattttt cactttttct actgcttctt ttgccgtctt gtattggtcg cgtgttgctg
    74881 aatccactac ttttccgtct ttaaagacta tagctgtttt ttctttagct gtttgcaatt
    74941 cagcatattg atttttagct tctgtttgtg cttgttgaat caattttcca aaatctgtgt
    75001 tatccgtttc gattgcttgg atctctttat ctgctttcaa cttgatgtca tctgctagat
    75061 gatcatcgac gatggcaggt gctatgaacc actcattcac tttttggata tctcggatct
    75121 tagattggat atcttggtaa gttgtttcta actctgaata tcctttttca ttcttaagac
    75181 tggataaatc attttttagt tttgataaat cttgatgaat catatctgca cgaataaatt
    75241 gatggtgatc atctgtataa aaggcagcaa gtttctcatg aagttcttcc atttgttgct
    75301 gtctttttgc ttctgctgct acttcggctt ctactttttg atgatggtca taataagccc
    75361 agcttcctcc accgagtaga agtactgctg ctaaaacgag ataaggtact ttttttgatt
    75421 ttttcttttg cgctttatct ggatctgttt tttctaagtt tgattcttga tgtgtttttt
    75481 cagtatctgg cacgattgtt attgatttcg cttctgcttc aaacagctta ggctggttct
    75541 cttctttttc tatttttgct tcaagatcag taccctcttt gcttacagat tgattttcag
    75601 catcggattc actatttatt tcatcgggct ctgttgactt tttgtctgtg ttttcgagta
    75661 tttctttttt ctctgcttcc ggcagtttat tcgttttttc cttttctaat tgtttttcag
    75721 taaatacttc agttttttct gtgatatccg tttttacgtc ttttattttt actgtttctt
    75781 tacctgtggc gttttctcta tcagagtctt tttcagtttc ttgttccttt tctggctcta
    75841 ctttgttttc ctgtgcaatt ttttcactga tcattttgag cagctctttc gcgtgctctt
    75901 cttttgtatc ttcacgatgt gctttgatat aagcggatag tatcgaattt tcttcctcat
    75961 tatcgacgat ttctttcagt tcagctactc ttcttttttg ttttgattca agcgtttctt
    76021 cttgattctt tcctgattct tccgaagtct catgaacagt tgctttcttc tgttcatttt
    76081 tctctatatt agttacttga tcgtgagcag gtggttcttc gtcttctggt tctgcttttt
    76141 cgaataattc cattacagat tctagaggta aatctttcaa ttccgaccat tcgattggat
    76201 cgtttaattc tgtatcagga aagactgcat cttcagttga tttatcctgc atagctgcat
    76261 ctgtatttgt ttcttcaatt gattctttta tttgctgatc ttctgcagtt atttgatgac
    76321 cgcagtctgg acagatagta ttctgctcca tttttttcga tccgcaattt ggacattttt
    76381 tcatcactta gcgatcggct cctttactag gtttacgcta ccatttaatc tatcatattc
    76441 tatacgtcac gccaatagct tatttttagg atttacttaa aaataatgaa tgaatttcct
    76501 tcctatagaa aaaaaagctt gagactgcgt agtctcaagc tttttttctt ttaaaataaa
    76561 ccaaacagtt ttactgattt ctcttctggt caatagtcca cgcttattct aagaaatctt
    76621 ttaattgttt tgaacgagaa ggatggcgca attttcttaa tgctttagcc tcgatctgac
    76681 gaatacgttc ccgagtaaca ccaaatactt tccctacttc ttccaatgtt ctcgtccggc
    76741 catcatctaa accaaaacgt aagcgaagga cattctcttc ccgatcagtc aatgtatcta
    76801 gtacatcttc caattgttct tttagtaact cataagctgc gtgttctgct ggacttgttg
    76861 cttcctggtc ttctatgaaa tcacctaagt gagagtcatc ttcttcaccg attggcgttt
    76921 caagggaaac aggttcttgc gcgattttca agatttctcg gactttttct gttggaagat
    76981 ccatttccgc accgatttct tctggcgtag gttctcttcc aaggtcttgc agcaattgac
    77041 gttggatacg tatcaattta ttaattgttt caaccatatg aactggaata cggatcgtac
    77101 gtgcttggtc agcgattgct cgagtgatgg cttgacgaat ccaccatgta gcataggttg
    77161 aaaacttaaa tcctttgcgg tagtcaaatt tttcaactgc cttcatcagt cccatgtttc
    77221 cttcttggat caagtcaagg aactgcatgc ctcgtcctac ataacgttta gcgatactta
    77281 ctactaaacg aaggtttgct tctgccagac gctgtttcgc ttcttggtcg ccttcttcga
    77341 ttttcaatgc taacgctact tcttcttccg cagttaaaag ggagacacgg ccaatttctt
    77401 tcagatacat acgaaccggg tcattgattt ttacaccggt tggcgcagaa agatcttctg
    77461 tttttgcttg ttcagctttt ttctcagcac tcttcaagct gtgaattgat ggatcaccat
    77521 tttcatccac cacactgata cctgcgtctt caatcttttg gatcaatttg tccatttcat
    77581 ctgcattcaa agtgaatggt gtagcaagct gattggataa atcatcatat acaacttgtc
    77641 gtttgggttt gttttctttg atgaaagctg ctactgctgc ttcatacgtt tttttatctg
    77701 ttccatttgc cataaaagaa ggcccccctt gagtagctat ttggcttgtt ttaactgttt
    77761 cgttaaattg atgatttcaa tcgtcaattc aagctcaagc tgtttgtttc cagttcgtct
    77821 ggcttcttgc tgcatttgtt tttttaatgt tatttcatca gctaagccag atttgctgat
    77881 cacatctagc aagtcttgga tttctcgtgg cgaactttct tctgccaccg gtaaatattc
    77941 gatttccacc accaaccgcc ttaaattttc atcttgcaaa aagtctaaaa actctgcaag
    78001 gttgaattca taatgttgtg agacatatgc atcgaataaa aaataaactt ctgcatatgc
    78061 atcatgaata aactgaaatt ctcgttcttt taaaatatta cggacagaaa cttctttaaa
    78121 tgcacgatat aatagaatct gctctgcctt ttctacttgc gtcaaaggtc tctttttccg
    78181 tgcagtttct tgtctcgtaa cctgagtgtg ttgactttcc tgaggttctt gacgattttg
    78241 ctgatttgtc cttcgaagat cgcgcagttg tttttgtatc gtctctctgc cgatctgaaa
    78301 ctctgttgac agttgagata gatacatatc ttgttcgatt ggtgaaacaa ctcggctaag
    78361 ttcaactagt aattcttcga ggtattcgat cttgtctttt tcattatcta aatttttccc
    78421 ttgttttaaa taacgtgatt taaaagtaaa gactgtttcg cgcccatgag ccactaattc
    78481 ttggaaagat gcttctccat acttacggag atattcatca ggatcaagct tttctggaac
    78541 gactacgaca gaaagtgcta atcgactgtt ttgccgaagc aattcaatcc ctcgattggt
    78601 tgcttcaaaa cctgcgttgt ctccgtcata gcaaaagacc aattctttcg tcagcttttc
    78661 catttgttgg atctgttgag ctgttagact tgtccccata gaagctaatc cagttttgat
    78721 accagcctgc catgcagcaa tcacatccat aaacccttcg aacaacaaaa tttctccgtt
    78781 tttccggata tcgcttcttg ctttatcaag attaaataaa acttgtcttt tattgaacag
    78841 ttctgtttct ggactattca agtatttggg ctgatctttt tcctgccctt tttcaggtgc
    78901 aagccagcgt cctgaaaaac cgatcgtctg gccttgagaa ttacgaagtg gaaacatcac
    78961 tctttgataa aaacgatcag acatacggcc atcatcatgc gtgacaaaca atccagagcg
    79021 ttctaacaat tcatttgaaa ttgattcatt cttgaatact tgctgaagaa aagaacgctc
    79081 attaggtgca aaacctatgt tgaattcttc aattaattct aaagacaacc cacgactttg
    79141 caaatattct aaagctggct gtccagcttt tgtatgcaat agcatgtgat gatagatttc
    79201 cgctgctttt tcatgagcag caatcagttt ccccgtagca gattcaggat tttggacagc
    79261 tatagtacgc tgacgccatt gatcttctaa cggtatctgt tcgaagtctg ccacttttac
    79321 cactgcttct ggaaaactta gaccttctag ttcttgaaga aaagtaaaca cgtttccgcc
    79381 tttaccacaa ccaaagcaat gaaaaatctg cttgtcttct gcaacagaaa aagacggtgt
    79441 acgttcttca tgaaaaggac acagccccaa gtaattttta ccagactttt tcaactggac
    79501 atattgtcca atcacctcaa cgatattcgt ttgactgcgt actgtttcga taacctcttg
    79561 aggaatccgt tgagccattt tttcaccccc tgctctattg atatcttttg ggtttaacag
    79621 aagatatttc aggagaataa ccggtaaaaa atcgcactaa ctgaaatcag tgcgatttta
    79681 aaggacacaa ttatacatgt ttgattgtat catatttcat tgctttttca agtataacac
    79741 atttctatct cattaagcat caatttgcta ctcttttcag taactgattt tgaatatcag
    79801 ccttccagta caatactcga agaacaatat ttacgagcat gaatacaaag aagtatccta
    79861 cgctctctcc caaccctaag tttacttcca aaattccatg gaacagcatt gcagctacat
    79921 atatccctac gatcgtcgtt actgctagga agatgcgcaa tgggttgaag ggataacaag
    79981 cttttacaac tgccatgcaa ctgatcccaa tcagcaagta atacatcaaa gtagtagttt
    80041 cagcatttcc ccatgcgaat gtttttccaa gtagatacac cgcaatgata ttcactacta
    80101 caagcaaggc atttggtaaa gcattaataa gtgctgtagg caaataacgg taagtgattt
    80161 ttcttttatc ttgttcaaaa gataaaaaga aggaaggata cccttcaatc gctaaatcaa
    80221 tcagcgtgat ttggataggg ataaacggaa atccaattgc tgtaacggca catataatcg
    80281 ataaaataaa tgaataaatc gttttgataa aaaagatgcc tgagactttc gtcacattgt
    80341 tgaccactcg gcgtccttca aacaggactt ctggcaatgt agtaaaatca gagtccaaca
    80401 ataccagatt cgcaatctga cgtgttgctc catcaccttc tgccatagca atgctgcaat
    80461 ctgcttctct taacgccaaa acatcattca caccgtcgcc tgtcattgca accgttctgc
    80521 cgctttcttt caattcattt accagcaatt tcttttgctg cggactcact cgtccaaaaa
    80581 ccgtatagcg atgagcagct tctcgcactt ccatttcttc agtaatttga gaaagatcga
    80641 catacgcatc ataattcggt aatcctgcac gtctagcgat attggagaca gtaaaaggat
    80701 tgtctccaga aatcactttc agatccacac cttcctcatg aagataagct agtgtttctt
    80761 gagcgttttt tcggattgga tcatcgattt caaacagagc aaccggctca acaaatgctg
    80821 gtttttcttc gttcaattgc tgatttggag cgatccccaa cataagtacg cgatagccat
    80881 tcgcttgggc tgtttttaga ctgtccggaa gccgatcttc ttccaccaaa cgttcaggcg
    80941 ctcctacgta cacgactccc agttctggaa attccatcgc gccccatttg cgatcagaag
    81001 aaaatgcgac tttgtttgtc acatcatacc gattagaaag ctcaaaataa tctctcatag
    81061 cccgcatagt gatgttgtta tcactgcttt ctgccagata cgtccccata atttctggga
    81121 tggctttctc gtacagcgga tgtagtgctt ctacccgctg gatactcatt ttcccttcag
    81181 taatggtccc tgttttatcc aagcataatg tatcgacatg ggccagcgtt tcaattgaat
    81241 acatgtcttg aacaaggatt cgtttttttg ccagtttggt tacccctgtc gttaatgcaa
    81301 tacttattag caataccaaa ccctttggaa gcatgcctaa caaagctgct gcagatgcaa
    81361 taacagaaat tttgatagaa gcatcgcgga tgaacagtgc ttccaaaaat agtatgatcc
    81421 ccaaaggaat aatcacgaaa ctagtgaatt tggatacttt gcgaatcgaa tctacaagtt
    81481 cagaacgaat agctttgtga gtctttgcct cgctagtcaa gcggacagca taattatctg
    81541 cacctactcg gataacttca gccatgacag aaccgcttgt caaaaagctt ccagaaagca
    81601 attcagctcc agtttctttg acaatcaaat cagattcgcc tgtcaaaaga gcttcatttg
    81661 cttctgcccg tccagatata acctgtaaat cggctggtat ctgttctcct gctccgattt
    81721 ttaccaaatc tcctaatacc agctctttag tagaaatcga ttgttcttta ccgtcccgga
    81781 tcactagtac ttctgattgg gaaacaatcg ataatttccg tacaagattt cttgcatgta
    81841 tttcttgata aattccaata acgatattga cgacaataat tgctaaatac gccatgttgg
    81901 aatacgcacc tacaaataac agacaaatcc caataccaaa gttcagaaaa ttgaataacg
    81961 tcaatatatt atcgctgaat atttgttttg tactttttga tgcatcttcc tggtagtcat
    82021 tttgctggcc agaagccatt ttctgaacta cctcttgctg tgtaagtcca ttcattttct
    82081 ttttctccat tttccgccaa ctttcaaaaa taatcacgtg tttaagtcta gcgtgttcca
    82141 agattaaaaa caacttgttt ttataaaatt tatagaaaaa cacacgaatg attttacaaa
    82201 aaagatgcca acctttttgt ttgaatcacc cgtgtgctgt ttttattatc aatctatctt
    82261 tacttatatt gttcctccaa acggctcatc caccaaccta gtgctgtacc ggctataaaa
    82321 agaacaggac aagctagtac cccagcaact cccaatcccg cgtaatcggt aggaatgatc
    82381 ataatcgttg aagcaaaaac tacacctaaa atgaaatgga atagcttgct atatgccttt
    82441 gagaaaatgt aatccatgat ttttgacaat ccaagaacac aaagaatccc accaattccg
    82501 atcggcacaa tcacttcaag tcgtacttct ttaaatccgt cagccatcgc tttatacaat
    82561 cccatataca ccaaaaaatt agaagggctc aatcctggga cgatcatacc caaaccaatc
    82621 aatccgccgg caatcagcca tgttccaaaa ttctgatcga cttgcccgtc aaataattga
    82681 gcgccgtata ataaaaacaa ataagccaga acaaaagtaa caaccatgat gatcacatca
    82741 gaagtatctc ttcctttttt ccctgcttct ttccataacg caggaacagt tccagcgata
    82801 catccgacaa aaaaccataa tatcgttgtt tcatacgcac ctaataaaaa actgactaaa
    82861 aaagaaagta gaaagatgcc tgtcactccg cctagaccaa caggcagaaa aaacaaaaca
    82921 ttttctttga aattttttgt aaggtgggct aaaaaagaaa tcagccgctc atacatgcca
    82981 aagacagctg ctaatgcacc accgctgact cctggcaaga taaatcctga accgataaac
    83041 attcccttca caaaccgtaa catccagtct ttggttgtgt accccacttc ttgattttcc
    83101 attttttgcc ttttttccac tatttgcgta ctccttcttt catttaattt tattcatgat
    83161 tgaacatttc ctgctatttt acttaaagac tttttcatag gtctctatta ttttttcatt
    83221 cattttgaca atatcaggat aaaacatgtt acctccatta tgatagagat agccgccatt
    83281 gtaaagcaag gactggatcc gccaatatcg gtattgtttc ccttcctcat ttcctaaaag
    83341 tgggctcagc acatctttag aatacgcttc tgctaattct actgtgtttt ctccgccatg
    83401 attttttaca taggcaatat aatctttccc aaaattatat gcttggacag ctgtccataa
    83461 atcgcatcct tgtttctttg cttctactat catttccgcc aaatatttga caccttgatc
    83521 aatactgtca gctggattat caatgatctc agcttctcca tgcagacttt ccgagctctg
    83581 catgagatct gtcccttttc cttttgattc ggtcaatatt atcgccttga tcaaattctc
    83641 gtagttttcc atatgataat tttttgcagc tgttgttatt tctatttgat agctttccac
    83701 tcgttttacc gaacgataag ttcttcctca taaaaacaac accgcaccaa taaccgtcag
    83761 aatgatcatg taaaaaagaa tacggataat agataatcgt tttcgcttca tttcatcacc
    83821 tagttatttt gacatctttt tttatcttac tatttcttta tcttcttggc tatttcttcc
    83881 ttgatttctg tgtacgcctt aagaaaaaat gaattttcct gtattttttg acatcttacg
    83941 aaaatgatcg ttgtttttca gtaaaaacaa ttgcccaatg actgatataa tcgttatact
    84001 ttacacagta ggtgattatg tgaaaaaaga aaagaaatat gcaaaaatgc cagatgggag
    84061 cgaaatttac tatgaaaaga gcggtcaagg cttccctctc tttttactgc atggcaatga
    84121 cggcagcggc cgcttttttt cagaacaggt ccctgtactc gaacgctact ataccgtgta
    84181 tctagtagat agccgaggac atggtcgttc gacaaacgaa gcatctatgt tgaattttca
    84241 gttaatggcc gaggatctga atacgatcat gttgctggaa aaaatcgatc aggcagattt
    84301 tcttggattt agtgatggag caaatctagc actggtattt gccagcagct tccctaaaaa
    84361 agttcatcga ttgattttaa attctggaaa cacgcttgtt aaaggcgttc gtttttctgc
    84421 cagagtcatc agtaatattc attatgcatg ggtatggtta ctctctttat ttcgcccaag
    84481 tcttcgcaaa aatcttttag ttatcaaact tttgctgcat gacatcgggc ttacagaaaa
    84541 tgatttaaaa aaaatcaact cccccacttt gatcatcgtg ggaaaaaaag atgtaatcaa
    84601 gctaaaacat tctttgtata tagctaaaac tataccaaaa gcttcctttg tgcttgtgaa
    84661 agaacaagga catgaattag ctagaaaaga tcctgaacgc ttcaatcgag aagttcttca
    84721 atttctttct gaaacataac tattaggaat agaaggtgat ttatttgtta aaaaatacca
    84781 tacaatggct gaaaaaccac ctaggactgt tcaaaacaat ctttttgatt tctgtcattg
    84841 tcattattgt cggtgaattg atgtccatcg gtaaaactct atctatccag caattaggag
    84901 aaacgtttgc cactatacct gtatggaaaa gcggactaat gctattgatt ggtcttatct
    84961 ctgtgttacc tatggttggt tatgatatta ttttgaatcg gatgcttgaa caaaagcaga
    85021 atcctcgtta cctgtttgag acaagctggc tgatcaatac gatcaacaat attgccggtt
    85081 tcggcgggtt tgttagtgtg gggcttcgct ctgaactata tggacaaaag aaagagagca
    85141 gaaacgtgat ccaagcatta tcgaaagttt tcttgttttt gatggctgga ctttctattt
    85201 acagtctgct ttctttttta cttgtagtct tcacgccagt tgctcctttt ttgaagcaat
    85261 attggatatg gttgatcggc ggcggtctat attttcctgt cgtcttttta tttactactt
    85321 tcaaaaagaa aggattcctt ggtggtacct cacttaaaac tcaaggacag ctattgctag
    85381 tttcattgtt ggaatggacc ggtgtcctgt ttagtttcct ttctgttggt tatttaatgg
    85441 aaatccggat tgatctgtgg caaacaattc cattattcat tgctgcttca gtgataggaa
    85501 tcgtgtctat gattccagga gaaattggga gtttcgatgt aatgatgatt atcgggttgt
    85561 ccgctattgg tgtgccaaga gaaatagtcg ttgtgtggat cttgctctat cgcctgttct
    85621 actacatcat tccgtttttg attggaatcg tctttttctt caaaaatatc ggttccactt
    85681 ttgatcagcg ttattctggt atccctaaac aattagcaac agaaattgcg cataaaatcg
    85741 tggttgtctt attatacttt tctggaatca tgctagtact ttctgccact atcccgcaag
    85801 cttttacaga gtttcgctgg cttcatagtt tgaacccatt gaaatttcat tttattatcc
    85861 aatttcctag tatactattg ggatttcttt taatcattat gggcagaggg atcgcagcac
    85921 gtgtgaaacg agcatatttg cctacaatct tcttgattgt tctagcttta ctttatgttt
    85981 tattaagtga ttttagtttc acaccggtgg ttttcttgtc tattctgctt ctgatcattc
    86041 ttgcttctaa aaacgaatta tttcgggaac aattgatcta ttcatgggag tggcgtacga
    86101 tcgatggaat cattattggt gcactgtcct tgctttacat cgttattggg gtatacaatc
    86161 tgccggattt ccctcatcgg cgtcaccatt ttatttcctt tttcttattt ccttctgaaa
    86221 agatttggtt ttcgggattg ttggccatca tcgctgttag tttcatgatc gttctatttg
    86281 ttcatttcct tcaaggagaa aagaaacaga ttggcgaagc ctttaatgaa gaaaaggccc
    86341 tgaagatcct tacaacttat ggaggaaact ccgatagtca attgatcttc ttaaaagata
    86401 agcggatgtt tgcctatgaa aaagacggtg aaccaactgt tcttctccaa ttcgcttgct
    86461 tcaataataa atgtattgta atgggtgatc cttctggtaa gaaagaagat tttccagaag
    86521 caatcgaagc ttttatcgaa gaaacagatc gactatgcta tttaccagtt ttctacgaaa
    86581 caagcgaaga gattgttatg attttgcatg aattcggcta cgatttcatt aagatggggg
    86641 aagaagctta tgtagacctg aatagtttta caacttcagg gaaaaaaatg aagggcactc
    86701 gtgctgtctt gaatcggatc gaacgagaag gatttacatt tgatgtctta caaccaccat
    86761 tttctactga gcaaatgagt actttcaaaa atatctctga taattggttg ggttcacgaa
    86821 aggaaaaagg gttttcttta ggctttttct ctgaagatta tctacaaaga gcgcctattg
    86881 cagttgtcaa aaatacccaa gaagaaattg tcgcttttgc aacgatcatg cctacttaca
    86941 cgaacaataa agtaggaacg attgatctga tgcgatatga ttctaaaaaa gcaccttctg
    87001 gcagtatgga tttcttgttc ttgcatttgt ttgcctatat gaaagaagaa catatccaat
    87061 ggttcaattt agggatggcc cctctttcaa atgtcggaac ttccagaaag agttttttac
    87121 aggaaaggat tgcatacttg gtttacgagt ttggttctca tttttattct ttccatggat
    87181 taagagaata taaaagcaag tacgctacaa actgggtctc acgttatact ctatattcta
    87241 gagatagttg gattgcatat gttatgattg ctttgctgat tattgataat gcgccagttg
    87301 agcagacaca aggtagaata agtggtttga aaaaatggat acgaagaaag tgttaaaaac
    87361 tgcataccga tagatgaaca ctctcatgat gaataaaaga gactgaagta aaacgaaagt
    87421 tcatgcttct acaatctctt cttatacaat tgaagaacaa agagcggtcc aaacagaaat
    87481 cctgtttgga ccgctctttt attttaaaca tttttcatta ccaaaatatt cgagtcgcgt
    87541 ttcttatgct tcgatctctg taacgatacc tgaacctact gtccgtccgc cttcacgaat
    87601 tgagaatgtc gttccgtttt caacagcgat tggatggatc aagtcaacat caatcgtcac
    87661 gttgtcacca ggcatgacca tttctgtatc ttctggcaat gtgattgttc ctgtaacatc
    87721 agttgtgcgg aagtagaact gtggacgata gttgttgaag aatggagtat gacgtccacc
    87781 ttcttctttt gtcaacacgt acacttctgc tttgaatttt gtatgtggag taatggaacc
    87841 tggtttagca agtacttgtc cacgttcgat atcgtcacgt tggatccccc gtaacaacac
    87901 gcctacgtta tccccagctt ccccgtaatc taacgtttta cggaacattt ctacacctgt
    87961 tacaactgct ttttgtgttt caggtttgat ccctacgatc tctacctcat caccgacacg
    88021 aacagcacca cgatcaatac gacctgaggc aacagttcct cgacctgtaa ttgagaagac
    88081 gtcttccact ggcaatagta atggtttatc tgtatcacgt tctggtgttg ggatatattc
    88141 atctactgta tccatcaatt ccataatagc agcttcagca tctggatcgc cttgcaatgc
    88201 ttttaatgcg gaacctttga tcacaggagt gtcatcgcct gggaaaccat attcgctcaa
    88261 taactcgcga acttccattt ctaccaaatc gatcaattct tcatcatcga ctaaatcaac
    88321 tttgttcaag aaaacaatca ggtattttac accaacttgg cgtgacaata aaatgtgttc
    88381 acgtgtttga ggcatcggac cgtcagttgc agaaacaact aagattgcac catccatttg
    88441 tgctgcccct gtaatcatgt ttttcacata gtccgcgtgt cctggtgcat caatatgcgc
    88501 gtagtggcgt ttttctgttt catattctac gtgtgcggta ttgatcgtaa tcccacgttc
    88561 acgttcttct ggagctgcat caatactagc atagtcttga ggatttgcta ggcctttttt
    88621 gcctaatact gtagtgatcg cagcagttaa agtagttttc ccatggtcaa cgtgtccaat
    88681 cgtaccaatg ttaacgtgtg gtttacttct gtcataatgt tcttttgcca taatttacaa
    88741 acctcctaaa taatatagat cactgaaaaa tttcagctct caccttttta ttatagtctt
    88801 tttttgacta aatcaaaaag aatacgtccg acttactttt tgtaagattc gaactaagct
    88861 tattatacgt caatattggt caaagtcaac taagagcact cgtctgtctt atacgcgaaa
    88921 aaagtacctt ttataaataa aaaaatgtgt tttttgagaa aaacttcaag atagtcctta
    88981 actttctttt gaagcaataa gaacaaaatg aggaaaagtt taaaattcag ctgttgccaa
    89041 caactttcaa tagacgaaat cttctatttc gttaataata aggaaagagg tgaagtacat
    89101 gaaaaaatta attggcgtac ttgtcgtttt aggcatattt ctcggcggaa gttttgcagc
    89161 ttatcattat ttttacggcg gcgaagctta ttatacaaaa atcacgacga atggcgaaat
    89221 gtcagctacc caagcagata acggagagaa attcacgact tatacctaca agcaagcggc
    89281 ttataataaa gatggtgaaa aaaaacaggt gacgcttcgc gaagaaagag aacatccatt
    89341 aaagatgaat gcgtatctta aactcaaagt caatcctcgt aaaggtgtat taagctggga
    89401 agaaataaag gcttctgaag tgcctaaaaa tgcggcagaa aaaatcgata attagtaaat
    89461 ggtcttaaaa ttttattaga taaaaagagg ctgggacaga agcgtttaac tccaagaaat
    89521 aagaaggagt tgcttctgct tccgccgttt atacgtgttt agagcgtgag acaaaagtgt
    89581 tctttacttt tgtctcacgc tctttttttg ttatattcgt cttttccgat ccttctcttg
    89641 acacaattca tttaactgat cactggtact tgaacaccta atattctagt catttttata
    89701 aacgattcaa tacttcatcc acatttttga tcatcacgga tatcgtacca tccggattat
    89761 tcacaaattc aatcaaatct gggttgcgat atacatctac tggtacgatc agttcgatcc
    89821 cgtttgatag cttgaatttt tgttttccaa attttttctc agaaatttct tgtacttctt
    89881 ttacaggagg tgcttctggg acaaatcctt gctcttgtac ttcttcttta aaagccattt
    89941 ttgccgtgat gttttccttg aagacttttt ccgcaatcat ctcatgatcc aaccgacctt
    90001 tttcttctat cgtatcatag acagcttctt tcaaatcagc catgatatca aattcttctg
    90061 tctcaaattt ttttccaaga tgcttggcta ctttttggat cacttttaca ttttcttcta
    90121 aagaaggtgc aggaacactt tcgatcactc ttccagaaaa ataaagctct tttttgccag
    90181 aaaactcata ttttttttca attaattcgt aggtccaatc agtcaaattc acagcgaatg
    90241 cttcatctgc tttttgtgtt ttcgccccta gaattgctcg attcaaaatc aagcggttgt
    90301 cgatccctgc ttcgtctgct tcaacaaagt gagtgtaagc ctcacgataa ttgactttca
    90361 ataaagataa gtacatcact gtatctaatt catacaagac aacaaataca tctgcactag
    90421 gtgcttcttc actttcttgg tagatatcga accaccgctg aacgattgct tcacttgctt
    90481 ccacaaaatt ttcttgagcg attttaagtg attcaacgat catgctttct tctgctagtt
    90541 gtccagtttt tgtttgagca gaagagattt tttggatctt cttttgaaga aaatcacgaa
    90601 tatattcttt tgtcagatcc agctcttttt gtgaaaagac tggagaacca gtttctctgt
    90661 caataatatg cagaattgct ttttttaaat agatatccat tttctcattc ccttctgtct
    90721 tagtttacgg aaaaaaaatc aaaaatacca gaatcaaaat cattttcttt taaacaaaaa
    90781 tttcaagagt agaaacaaaa tggattcttt ttttcgaaaa atgcgctaca cttatagttg
    90841 aacgaataaa aaaggagctg aaagtatgaa ttcattaaca agcacttatc gtctatcaaa
    90901 tggttacgaa atcccggtag taggattcgg cacatggcaa acacctgatg gggatgtcgc
    90961 tgtttcctct gttaaagaag cgctggctgc aggttatcgc catatcgata ctgcccaagg
    91021 atacaagaat gaagaaagcg tcggccaagc gattaaggaa agtggaattc ctagagaaga
    91081 gatattcttg acaacaaaat tatggaatgc aaaccacagc tatgaacttg tgatgtcttc
    91141 ttttgaagaa tcattgaaga agctccaaac agattattta gatctgtttt tgatccactg
    91201 gccaaaccct gttgcttttc gtgataattg ggaacaagca aatgcagata catggcgagc
    91261 atttgaagaa ctgtatgaag caggtaaaat caaagcaatc ggtgtgagca atttcttacc
    91321 ccaccatcta gatacactag caaaaacagc aaaaattatg ccgatggtca atcaagtttt
    91381 ccttgcacca ggcgaattac agacaactgt agttgagtat gcaaaaaaac atgatatgat
    91441 cctcgaagca tatagtccat taggcactgg taaaatcttc gatgtgcctg aaatgaaaca
    91501 aatcgctgaa gcacatgaca agacgattgc acaagttgct ttgcgttggt cgctgcaaca
    91561 cgaattcctt cctcttccta agtcagtgac accaagcaga atcaaagaaa atactgaatt
    91621 atttgatttt gaattaacag aagaagaaat gaaacaaatc gatcagttag atggtgtagt
    91681 cggcaaagca aaagacccag atactaccca attttaagtc gaaaggtgat tttatggatc
    91741 caatcgaacg cttgaattct ctctcggaag aagttaccca gacttttcat tccgattttg
    91801 tctttttgat cgatgcagag aaaatccaac attttcctgc aagaaactgg acacatgatc
    91861 aaatcatcga agaactgaaa aaacggttcg atcattcgct aatggtcaaa ccctggcacg
    91921 aacatgaagt catttattca cctgaactac ctgtttttgc cttgataccg aaaaaataga
    91981 aagaatgg
//
LOCUS       DADQDV010000002        89987 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.002, whole genome shotgun sequence.
ACCESSION   DADQDV010000002 DADQDV010000000
VERSION     DADQDV010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 89987)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 89987)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..89987
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.002"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(69..1490)
                     /locus_tag="J8S10_000089"
     CDS             complement(69..1490)
                     /locus_tag="J8S10_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAZ9628709.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(1733..3610)
                     /gene="tdc"
                     /locus_tag="J8S10_000090"
     CDS             complement(1733..3610)
                     /gene="tdc"
                     /locus_tag="J8S10_000090"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HAZ9628710.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(3901..5157)
                     /locus_tag="J8S10_000091"
     CDS             complement(3901..5157)
                     /locus_tag="J8S10_000091"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HAZ9628711.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     gene            5737..7038
                     /locus_tag="J8S10_000092"
     CDS             5737..7038
                     /locus_tag="J8S10_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HAZ9628712.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(7107..7706)
                     /locus_tag="J8S10_000093"
     CDS             complement(7107..7706)
                     /locus_tag="J8S10_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAZ9628713.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            7961..8842
                     /locus_tag="J8S10_000094"
     CDS             7961..8842
                     /locus_tag="J8S10_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9628714.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            8855..10465
                     /locus_tag="J8S10_000095"
     CDS             8855..10465
                     /locus_tag="J8S10_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HAZ9628715.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(10542..11201)
                     /locus_tag="J8S10_000096"
     CDS             complement(10542..11201)
                     /locus_tag="J8S10_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAZ9628716.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(11484..12149)
                     /locus_tag="J8S10_000097"
     CDS             complement(11484..12149)
                     /locus_tag="J8S10_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9628717.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(12296..12901)
                     /gene="dhaL"
                     /locus_tag="J8S10_000098"
     CDS             complement(12296..12901)
                     /gene="dhaL"
                     /locus_tag="J8S10_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HAZ9628718.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(12929..13912)
                     /gene="dhaK"
                     /locus_tag="J8S10_000099"
     CDS             complement(12929..13912)
                     /gene="dhaK"
                     /locus_tag="J8S10_000099"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HAZ9628719.1"
                     /translation="MKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRVVAKNQKAEQ
                     VGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEADSGKGVLLIV
                     KNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAGTVLVHKIVG
                     DAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDEIEYGVGIHG
                     EPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQFVFMNDVLA
                     LLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTISW"
     gene            complement(13914..14309)
                     /gene="dhaM"
                     /locus_tag="J8S10_000100"
     CDS             complement(13914..14309)
                     /gene="dhaM"
                     /locus_tag="J8S10_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HAZ9628720.1"
                     /translation="MKKSILLISHSQKVTDGIKEMIEQMQKSEEVQIFSLGGINGEIG
                     SDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEEEQQQRYHLVDAPLVEGA
                     FAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            14463..14783
                     /locus_tag="J8S10_000101"
     CDS             14463..14783
                     /locus_tag="J8S10_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HAZ9628721.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(14895..15764)
                     /locus_tag="J8S10_000102"
     CDS             complement(14895..15764)
                     /locus_tag="J8S10_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAZ9628722.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(15860..17164)
                     /locus_tag="J8S10_000103"
     CDS             complement(15860..17164)
                     /locus_tag="J8S10_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAZ9628723.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(17161..17670)
                     /locus_tag="J8S10_000104"
     CDS             complement(17161..17670)
                     /locus_tag="J8S10_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9628724.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(17845..19980)
                     /locus_tag="J8S10_000105"
     CDS             complement(17845..19980)
                     /locus_tag="J8S10_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAZ9628725.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(20063..21718)
                     /locus_tag="J8S10_000106"
     CDS             complement(20063..21718)
                     /locus_tag="J8S10_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAZ9628726.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(21720..22034)
                     /locus_tag="J8S10_000107"
     CDS             complement(21720..22034)
                     /locus_tag="J8S10_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAZ9628727.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            22204..22464
                     /locus_tag="J8S10_000108"
     CDS             22204..22464
                     /locus_tag="J8S10_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HAZ9628728.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            22478..22792
                     /locus_tag="J8S10_000109"
     CDS             22478..22792
                     /locus_tag="J8S10_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur reduction protein DsrE"
                     /protein_id="HAZ9628729.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(23522..24076)
                     /locus_tag="J8S10_000110"
     CDS             complement(23522..24076)
                     /locus_tag="J8S10_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HAZ9628730.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(24202..26131)
                     /locus_tag="J8S10_000111"
                     /pseudo
     CDS             complement(24202..26131)
                     /locus_tag="J8S10_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(26437..27153)
                     /locus_tag="J8S10_000112"
     CDS             complement(26437..27153)
                     /locus_tag="J8S10_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HAZ9628731.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(27154..28977)
                     /gene="glpO"
                     /locus_tag="J8S10_000113"
     CDS             complement(27154..28977)
                     /gene="glpO"
                     /locus_tag="J8S10_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HAZ9628732.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(28991..30487)
                     /gene="glpK"
                     /locus_tag="J8S10_000114"
     CDS             complement(28991..30487)
                     /gene="glpK"
                     /locus_tag="J8S10_000114"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HAZ9628733.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(30623..32083)
                     /locus_tag="J8S10_000115"
     CDS             complement(30623..32083)
                     /locus_tag="J8S10_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAZ9628734.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(32073..33368)
                     /locus_tag="J8S10_000116"
     CDS             complement(32073..33368)
                     /locus_tag="J8S10_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAZ9628735.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(33700..34377)
                     /locus_tag="J8S10_000117"
     CDS             complement(33700..34377)
                     /locus_tag="J8S10_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HAZ9628736.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(34407..35498)
                     /locus_tag="J8S10_000118"
     CDS             complement(34407..35498)
                     /locus_tag="J8S10_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HAZ9628737.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(35599..36033)
                     /locus_tag="J8S10_000119"
     CDS             complement(35599..36033)
                     /locus_tag="J8S10_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAZ9628738.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(36617..38074)
                     /gene="ascB"
                     /locus_tag="J8S10_000120"
     CDS             complement(36617..38074)
                     /gene="ascB"
                     /locus_tag="J8S10_000120"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAZ9628739.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(38071..39966)
                     /locus_tag="J8S10_000121"
     CDS             complement(38071..39966)
                     /locus_tag="J8S10_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAZ9628740.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(40024..41799)
                     /locus_tag="J8S10_000122"
     CDS             complement(40024..41799)
                     /locus_tag="J8S10_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAZ9628741.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARFPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(41849..43345)
                     /locus_tag="J8S10_000123"
     CDS             complement(41849..43345)
                     /locus_tag="J8S10_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAZ9628742.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(43539..45161)
                     /locus_tag="J8S10_000124"
     CDS             complement(43539..45161)
                     /locus_tag="J8S10_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HAZ9628743.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(45489..46802)
                     /locus_tag="J8S10_000125"
     CDS             complement(45489..46802)
                     /locus_tag="J8S10_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HAZ9628744.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(47047..47271)
                     /locus_tag="J8S10_000126"
     CDS             complement(47047..47271)
                     /locus_tag="J8S10_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9628745.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(47291..47659)
                     /locus_tag="J8S10_000127"
     CDS             complement(47291..47659)
                     /locus_tag="J8S10_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAZ9628746.1"
                     /translation="MIQKTRVMLYVNDVEMICRFFVEKIGAEISETIELPEEFKSIVL
                     SISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETIYENMEEPGEITDNNGILT
                     FNFSDPEGNYFVIGKAESSD"
     gene            complement(47855..48565)
                     /locus_tag="J8S10_000128"
     CDS             complement(47855..48565)
                     /locus_tag="J8S10_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9628747.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(48583..49080)
                     /locus_tag="J8S10_000129"
     CDS             complement(48583..49080)
                     /locus_tag="J8S10_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAZ9628748.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(49117..49569)
                     /locus_tag="J8S10_000130"
     CDS             complement(49117..49569)
                     /locus_tag="J8S10_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003331879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAZ9628749.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(49704..50309)
                     /locus_tag="J8S10_000131"
     CDS             complement(49704..50309)
                     /locus_tag="J8S10_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HAZ9628750.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(50759..51379)
                     /locus_tag="J8S10_000132"
     CDS             complement(50759..51379)
                     /locus_tag="J8S10_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAZ9628751.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(51381..52250)
                     /locus_tag="J8S10_000133"
     CDS             complement(51381..52250)
                     /locus_tag="J8S10_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HAZ9628752.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(52273..52680)
                     /locus_tag="J8S10_000134"
     CDS             complement(52273..52680)
                     /locus_tag="J8S10_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HAZ9628753.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(52699..53988)
                     /locus_tag="J8S10_000135"
     CDS             complement(52699..53988)
                     /locus_tag="J8S10_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAZ9628754.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFNNATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(54015..54317)
                     /locus_tag="J8S10_000136"
     CDS             complement(54015..54317)
                     /locus_tag="J8S10_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAZ9628755.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(54342..56435)
                     /locus_tag="J8S10_000137"
     CDS             complement(54342..56435)
                     /locus_tag="J8S10_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAZ9628756.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(56924..57688)
                     /locus_tag="J8S10_000138"
     CDS             complement(56924..57688)
                     /locus_tag="J8S10_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HAZ9628757.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(57799..58668)
                     /gene="mdcB"
                     /locus_tag="J8S10_000139"
     CDS             complement(57799..58668)
                     /gene="mdcB"
                     /locus_tag="J8S10_000139"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HAZ9628758.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            complement(58693..59769)
                     /locus_tag="J8S10_000140"
     CDS             complement(58693..59769)
                     /locus_tag="J8S10_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HAZ9628759.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            complement(59793..60386)
                     /locus_tag="J8S10_000141"
     CDS             complement(59793..60386)
                     /locus_tag="J8S10_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HAZ9628760.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(60390..62066)
                     /gene="mdcD"
                     /locus_tag="J8S10_000142"
     CDS             complement(60390..62066)
                     /gene="mdcD"
                     /locus_tag="J8S10_000142"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HAZ9628761.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            complement(62056..62355)
                     /locus_tag="J8S10_000143"
     CDS             complement(62056..62355)
                     /locus_tag="J8S10_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HAZ9628762.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(62457..64103)
                     /gene="mdcA"
                     /locus_tag="J8S10_000144"
     CDS             complement(62457..64103)
                     /gene="mdcA"
                     /locus_tag="J8S10_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HAZ9628763.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNL
                     YTGFNTEETPTIIEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADKPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLRAAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            complement(64110..65021)
                     /locus_tag="J8S10_000145"
     CDS             complement(64110..65021)
                     /locus_tag="J8S10_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HAZ9628764.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            65141..65998
                     /locus_tag="J8S10_000146"
     CDS             65141..65998
                     /locus_tag="J8S10_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAZ9628765.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            complement(66185..66547)
                     /locus_tag="J8S10_000147"
     CDS             complement(66185..66547)
                     /locus_tag="J8S10_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9628766.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            66893..68332
                     /locus_tag="J8S10_000148"
     CDS             66893..68332
                     /locus_tag="J8S10_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAZ9628767.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            complement(68339..70891)
                     /locus_tag="J8S10_000149"
     CDS             complement(68339..70891)
                     /locus_tag="J8S10_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HAZ9628768.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(71005..72336)
                     /locus_tag="J8S10_000150"
     CDS             complement(71005..72336)
                     /locus_tag="J8S10_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAZ9628769.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(72302..73780)
                     /locus_tag="J8S10_000151"
     CDS             complement(72302..73780)
                     /locus_tag="J8S10_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAZ9628770.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(74085..75920)
                     /gene="tdc"
                     /locus_tag="J8S10_000152"
     CDS             complement(74085..75920)
                     /gene="tdc"
                     /locus_tag="J8S10_000152"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HAZ9628771.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
     gene            76390..77817
                     /locus_tag="J8S10_000153"
     CDS             76390..77817
                     /locus_tag="J8S10_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAZ9628772.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(77909..78274)
                     /locus_tag="J8S10_000154"
     CDS             complement(77909..78274)
                     /locus_tag="J8S10_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HAZ9628773.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(78271..78636)
                     /locus_tag="J8S10_000155"
     CDS             complement(78271..78636)
                     /locus_tag="J8S10_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HAZ9628774.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(78828..79076)
                     /locus_tag="J8S10_000156"
     CDS             complement(78828..79076)
                     /locus_tag="J8S10_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9628775.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            79075..79203
                     /locus_tag="J8S10_000157"
     CDS             79075..79203
                     /locus_tag="J8S10_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HAZ9628776.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            79260..80954
                     /locus_tag="J8S10_000158"
     CDS             79260..80954
                     /locus_tag="J8S10_000158"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HAZ9628777.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            80958..81077
                     /locus_tag="J8S10_000159"
                     /pseudo
     CDS             80958..81077
                     /locus_tag="J8S10_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
     gene            81159..81350
                     /locus_tag="J8S10_000160"
     CDS             81159..81350
                     /locus_tag="J8S10_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9628778.1"
                     /translation="MDLLPQMQAFEHHLPRGYEKAALHQVIRAAKLKQLLMFLTWLDL
                     LPQMQAFEHRLPRGYEKGV"
     gene            81728..82861
                     /locus_tag="J8S10_000161"
     CDS             81728..82861
                     /locus_tag="J8S10_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HAZ9628779.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            82892..83212
                     /locus_tag="J8S10_000162"
     CDS             82892..83212
                     /locus_tag="J8S10_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9628780.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(83241..83705)
                     /locus_tag="J8S10_000163"
     CDS             complement(83241..83705)
                     /locus_tag="J8S10_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAZ9628781.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(83836..85089)
                     /locus_tag="J8S10_000164"
     CDS             complement(83836..85089)
                     /locus_tag="J8S10_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAZ9628782.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLANGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     VNLGGTGATLGLLLAIYLVGRKNKPYMVVTNLPIAPGVFNINEPTMFGLPIVLNPIMF
                     IPFILTPMVLVSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGVLAAVNLV
                     LSILIYLPFVKVATIQERRKEALDA"
     gene            complement(85118..85435)
                     /locus_tag="J8S10_000165"
     CDS             complement(85118..85435)
                     /locus_tag="J8S10_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAZ9628783.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(85461..85781)
                     /locus_tag="J8S10_000166"
     CDS             complement(85461..85781)
                     /locus_tag="J8S10_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAZ9628784.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(86245..87660)
                     /locus_tag="J8S10_000167"
     CDS             complement(86245..87660)
                     /locus_tag="J8S10_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAZ9628785.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(87677..88993)
                     /locus_tag="J8S10_000168"
     CDS             complement(87677..88993)
                     /locus_tag="J8S10_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAZ9628786.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(89143..89841)
                     /locus_tag="J8S10_000169"
     CDS             complement(89143..89841)
                     /locus_tag="J8S10_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HAZ9628787.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
BASE COUNT        26174 a        18964 c        15419 g        29430 t
ORIGIN      
        1 aaaactattc acttggcagg acctcctact aaatcagcga caaaacgtcg gctgaaagac
       61 ttattttttt atttttcttc taaacttttt tctacctcaa tcccccaaga atctttcttg
      121 aagtgattga tgatcaatgg aataacgaac atgaccactg tgatagctgc tactaataat
      181 gcatcactca atgtcgctgt acctaatgta gcaaatacga caacgatgat agagaagatc
      241 agcatgcagc tgactaccca agctaatccg tttccgtttt taccaattcg gtaaggacgt
      301 tcgaattctg gatgtttctt acgcatttta agcaatgaaa cagcaatcaa aatgtacacg
      361 atacaataaa taacagttgt agcatttgta agtgtcaaga atacagcact tacgtcatcc
      421 attacaccat aaagcaaagc aaataatgaa ataacgattg attgtgttag aacgacattt
      481 ctagatacgc cgtatttgtt ttctttatgg aatccgaatt ttggtggaag gaatccttca
      541 cgagctactt ggatgattgt ttttgatggt ccagtaaccc aagctgataa ttgtaaaagc
      601 acaccaataa ataccatgaa gctgaagata tttccgatca cttctggtaa gcctaggatt
      661 tgacagtcaa tcaagatagg ctgcgtgata tttgctaatt ccatttttcc atctggtacg
      721 acatttgcta caagcatcgc attgatgaca ttcaataaaa ctaatccgat caaagcgata
      781 aatacgcctt ttgtataatt ttttgttgcg tctttcaaac gaggcatgta aacagaactc
      841 atttcgatcc caacaaaaat aaatgtgata ccagctaagt atttcaatga atcaatatgt
      901 tccaagtcag ggaaagcttt tgaccatgaa aagtcaccta gatagccgtt tgagactagt
      961 ccgactttga aggctgccaa aacacctaaa acgaacatga tgactactgg gatatatacc
     1021 cctagccata caccgatgtt cccgccgact tttgccatat cgaatttcaa gttcaagatc
     1081 gtgatgatcc agtagataac taaaatacaa cctaaaacga accagtgatt attgccaagt
     1141 tctacattac caaatgtgtt tcctaacaat ggtcctaaag tagaagcgac cattaccata
     1201 cctgggaaca tttgcaccca taatagccat gcaacgacaa atccccattt gctgcccagt
     1261 gctgttttta cccataactg aggaccgcct tcttgaggaa gcatcgtgga aagctcaccg
     1321 gaaaccattg atatcggacc ggcaaaaaac aaaactgcaa aaattgaata aaaaatcaat
     1381 gtccaaccga ctgcggctaa cgtaggaata ctccgaaccg ttgcacacag tgccattgtc
     1441 agaccgataa aggtcccaag acccatttta cttacttcag atttactcac cgttgacact
     1501 ctccttgatt ttttggataa aataacggtg tctttgaagt agtttcagca ataaacgaaa
     1561 caattcagcg aatatttgag gggattcttt gagtttattg cttgaagggt ttcttcaaag
     1621 acaacctcaa aacaaaggga tcgaagagct taggtctccc cttgctcttc agatccaaac
     1681 atgcgtcaga aacagttagt attcaagctg ttttctaaca tgattacctt gcttattttg
     1741 cttcgcttgc caataattgg tctgcgtaga ttttttccaa tttttcttga agagctgctt
     1801 tgattttttc agcatattct tcaaagtgtt cttctttgtt catgtatggt gtcattacgc
     1861 tggcacgcaa tacagttact tttccggcac ggttccattc ttcatctgag aatcctagtt
     1921 ggttcacaaa ttgtaatggg ctgttgccat agtctgggat agcaaagtca gtatgtgaag
     1981 ttaagaactc attaccgtaa atgcttcctt tcacgtatga agaataatca tatacgtcat
     2041 ggttcaattt attcattgca actaagtcat cgttgccttt ttctttgaat acatagtcta
     2101 ccatattgaa atctggataa gttaatggat gaacttcgat ttctttgtct cctactttaa
     2161 atgacaagtc attcaagaag ttgtagaaac gatgtgcacc ttcgattgat gcacccatta
     2221 atttaccata tcctgtgaca ttcaaaggta agacatggtg tgctgcccaa acgctggctg
     2281 ctgttgcccc tgcttttgaa ccttccaaga tataagcccc aagtaatgct gggatatctg
     2341 cgcctttttc aaatacatat gtcgcaaagt aagagataac gtctctcatg cggatatctt
     2401 tgatgacgat accaccggca gaatatggaa catagcccat tttatgtggg tcaatcgtta
     2461 cagattctgc ttcttcgatt gctttatatg cactgtgtac ttcttctaag atataatctt
     2521 tgttttctgt aaagacattg tatttgtaat gaacatcttt taaatcttca aatggaatga
     2581 agttgttgtc ttcgtctaag aaaatcgcac ggccgtatcc gccataagca gcatctacgt
     2641 gtaagtagaa gtaaataccg tctttttcta atacgcgacg caatgcaacg attttatcga
     2701 taccgtcgat tgctccttct tctgttgatc ctacaacacc gactacacct aggattggtg
     2761 ttttttcagc tgctagacca cgaacgattt tttcaagttc gttgatgtcc atgcgatagt
     2821 tgtggtcaac tggcactgga atcacttggt ctaaaccgat accgatgatg tcggcagctt
     2881 ttagccatga atagtgttta gtttgtggaa ccaaccattt tcctaatttt tctaaatgtt
     2941 ttccgctacg tgctgagtga gctttgattt cgtcgatttt ttctgggacg ctgtctaaca
     3001 gattcatgat ttcttctgtt gacaagttca ttaattccca atcgcttttt ccagcaacta
     3061 gttcaggtgt cacttctttc attgcaagcg gcaatgattt gatgttgcgg gcataccaaa
     3121 gtccttctaa gtttgctaaa gaaccatcag caacgatgtg gccccagcca tctttatagc
     3181 tcattaattt tgcaaattcc attcctactt cttcttccat ttggcttgtt gcaggagaag
     3241 attcataggc aacgttatta ccattccata gcatagcaaa attgtacgct agtaaagatg
     3301 gcatcaatgt ttcagagttc atatgacccc agtaacgtcc ggcattatgc caaggaacgg
     3361 aatgggtacg catccgcgct gaaatttctg atagaacatc ctttgtttta ttcacagtgt
     3421 gttcaaaact agcactgctt ttttcttctg gcgtaataat aggcatgtct tgaggcatgt
     3481 agttttgacg ccagcctaaa tgttcatcca ccaattcatt caacaaagct ttatagattt
     3541 ggccgttctc agctttgtcc ccaatgaata gggcatttag gtttagatct ttcgacaatg
     3601 attcactcat agtgaaaccc tcctaaaaaa atatttaaat tttgtcgagc cctacattac
     3661 acctgttctt ctattctgta aactaagttt tggcctgatt tttaatcata ttttaatatg
     3721 tatcaattat ccgaattgtt cacacttttg aaataattaa aaaaaacgag ggaatttaca
     3781 aatgtaaact ccctcgcaaa gattgtatta acgacaacca gcgttctatt ttaggatggg
     3841 tttcaaaatt ggaatgttgt aatagtattt ccctttttca aggtaaaaac ttactaaatt
     3901 ctaatcaatt actttggcca aaaagtaatt tttcttacct tttcgaataa ccacaaactt
     3961 accatcgaat tcatcggatg gatttatgac aaaatttaaa tcggtaacgc ggtcaccgtt
     4021 aatacttata gctccgtttg aaacatcttc acgtgcttga cgtttagatg gttcaatttt
     4081 tgtggaaaca agcagttcca cgatattttc aggtgtgctt gaaatttcaa cgttcggcat
     4141 tttaccgaat ccttgcgcga tttcttccgc atttagttct ttaatatttc cagagaacaa
     4201 tgcttgcgtt attttttgcg cttctttcaa gtcttcttca ctatgcacaa atcttgtaac
     4261 ttcttctgcc aaacggcgtt gtgcttcacg tttctcaggt tctgtctcta cttttttcgc
     4321 taagtcttcg atttcttctt gagacaagaa agtaaagaat ttcaagtatt tcactacatc
     4381 gcgatcatct tgattcaacc agaattggta gaactcaaat ggtgaagttt tcttcggatc
     4441 aagccaaacg gcaccgcctg cagtttttcc gaatttcgtt ccgtcagcct tcagcatcaa
     4501 tgggatcgtt aaaccgaacg cttctgcttc tggtccttct aattttcgga ttaggtctaa
     4561 tccagctgtg atatttcccc attggtctgc tccaccgatt tgcaattgca catcgtatgt
     4621 tttatgcaga tgcaaaaagt cgatagattg caggatttgg taagtaaact ctgtaaatga
     4681 gattcctact tccaaacggc tggcaacgat atcttttgct aacatcgtgt tgatgttgaa
     4741 gtttttaccg tagtctctca aaaattcaag taaagagatt tttgacaacc agtcgtagtt
     4801 gttcacaaat gtgatatttg catctttacc aaacaatttt ctcatttgat tggaaagtgc
     4861 gtccacgtta tgttgcactt gttccatcgt ttgcaacaca cgttctgttt tgcggccgct
     4921 tgggtcgccg atcgttcctg ttccgccgcc aatcagaata tatggatgat ggcctgccaa
     4981 ttggaatctt ttcatcatca taaatggaat caaatgtccg atatgcatcg aatcaccagt
     5041 tggatcaacg ccgcaataaa gtgaaatgct cttttcttca acgagctcgc gaagtctttc
     5101 ttcgtttgtt tgctgattaa tggcgtcgcg ccaagttaat tcatcaataa tattcatttt
     5161 actgacctcc gtgtagtttt tttatgaaag caggaacctg ctagcatgtg taattaatta
     5221 tttcttcagg ataggatagg aaataaaaaa agtcccttgg catataagcc aagggacgaa
     5281 atctcgcggt accacccaat ttgtatgtct agatatccaa catacctctc gaacatttaa
     5341 cgctgtcgcg tggcaatcac tgccaaagac tcctgaaatg taattcgctt taaagcatgt
     5401 actggtttgc agcgaccacc agctttctga aacattggct ttaacaacta cttcgtttcg
     5461 atcttcgtct tgttattatt aatatgtgtc tatcatagag cgcaactttt tctttgtcaa
     5521 cagaaaaagg atattttttt taaattcctc attttttctt ttttgaatcc gctctaattc
     5581 cgaacatttt attttcaatt attgttaaaa gaaataactt tttctgtatt ttttctgcaa
     5641 tttatcgaga agtcacttta ctttgcctct tattctttct tcgttacaat aaggaatggg
     5701 acaagtaaaa aaatgaaaaa gcaagggacg aggtatatgg aaaaaaagca aaaaattatt
     5761 ttaggagcca cttctgcttt aactatcgtt attttaattc taagtttgtt ttttgtcatc
     5821 cgatcatcta caaaaaaaga accaatcatt cctgaaaaaa aaataacaga aaaagcaaaa
     5881 gaaccgacag atgataagca acaactagtt actcaagcaa aaaatctggc tcaaagctac
     5941 gattatgacc aagcgattgc gttattggaa aaagatagta agaacggatc tactgaaaca
     6001 caacagcttc ttcaaacact aaaaaaggag aaagaacaac tgatcgactg gtctgatcct
     6061 actcagatct ctcatgtctt tttccacagc ttgatcgtgg acccgcaaaa agccttccac
     6121 tctcaacagg cacaaggata caaagattat atggtgactg ttgaagaatt caaccgttcg
     6181 atcgaacaac tttatcaaaa tgattttgtt ttagttaatt tgaatgattt gatccaaaaa
     6241 gacgaacaag gaaatctttc ctttaacggg cttgcgctac ctgaaggaaa aaaaccattg
     6301 gttctttcac aagatgatgt cagctattat gaatatatgg ataattccgg ttttcctagc
     6361 cgattggtcg tatcaaataa caatgaaatc aaaaatgtct ataaagagaa agataaagaa
     6421 gaaatcggtg actttgacat ggttcctctg atcgatgcct ttgtcaagaa acatcctgat
     6481 ttttcttatc gaggcgcaaa aggtaccttg gccctgacag gttacaacgg agttttaggt
     6541 tatcgaacat caaaatctca atatggagac aatgaaaaaa caaaaaaaga gattaaagaa
     6601 gctaaaaaag tggcggaaca gttgaagaaa gacggctgga gctttgcttc ccatacatgg
     6661 ggtcacttga atatgactca agcttcacta gaagatgtaa aaaaagacaa tgaattgtgg
     6721 cagcaagaag ttgcacctat cctaggaaaa acaaatattc tgatttatcc atttggtgca
     6781 gacatcagcg actggcagcc ttattcagca gaaaatcaaa aatttgctta cttgaagagt
     6841 caaggtttcg atattttctg taatgtcgat gcttctacac cagcttgggg acaattaggt
     6901 acggatttct atcgaaatgc tcggatcaat atcgatggca ttcgttttca atctgattta
     6961 gacggaaaaa atcctattct tgatccattc atcaatgtcc atgatgtcta tgacaaagaa
     7021 gcacgcgaat ctgcttgatt ttacgtcatt tatgaaccaa aaaagccgaa ctgacatttt
     7081 atcgtcagtt tcggcttttt tatgctttat ttcttcttcg gtgcgattcc cttgatcagg
     7141 acttctgtcc attctgctgt atatggaagc agttttgcgt atatctccgg cttagaaatt
     7201 ccttctacca ttgcttgaaa atagaggatc aagaactcat ccgaatattt caaatccact
     7261 tttccttctt tccgccctcg atggaaaaga tcaagcatga tactgaaact ttcttgcgta
     7321 tacgcatcca tcgcgtcaga aaattctttt ttttcttttt ttgtatagta tgtcatcaaa
     7381 tcgatataaa attgtttgtt cactcgattg agataacgga ttttgttttc actcatggca
     7441 atcagtgttt cttcaaatgg aagattttcc gcaatcaacg ctttcgcttc ttgccctaaa
     7501 tcattcataa atgcaaaaaa tacttcataa atcagccctt ccttgctgcc aaaatattta
     7561 aaaatcgtcg ctttacttac ctgagcgttc tcagctacct tatccattgt cactccagcg
     7621 gttcctatgt ctgtgttcat caagtcaaaa gctgcttgta aaatctcttt ctttttctct
     7681 tgtgctctct tttcaaaacc gttcatttgt agagcctccc gtaattttaa acttttataa
     7741 tatatatagt tcaaatttat tctgaggttt attataacta tctattgaga aagtatcaag
     7801 ctagcaattc cttgtttatg aattcattga cagaaattta taaaaagaat attatgtact
     7861 aaaataataa aaaaaagttt tataaaaagg tataaaacct ttttattaaa ctatttaatc
     7921 ttgtttagta tatattttta gaaaaaggag tggggttttt atggcagaaa tcgtcaaagt
     7981 cacacatttg aaaaagagct ttggtcgttt cgaagcttta aaagatgtct ctttcaccgt
     8041 acattcaggt gaagtcgttg gatttatcgg accaaatggt tctggaaaat ccacgacgat
     8101 tcggacactt ttagggatta taaaaaaaga cggcggaacg gcaacgattt ttgggcaaga
     8161 tgtatgggaa gatagtttat ctatccatga acgtctttct tatgttccag gcgatatctc
     8221 tttgtgggga aatttgactg gaggagcgat catcgatctc ttcatgaagc ttcatggaaa
     8281 agggagtgct caaaaaaaag atgaactgat tcaacgtttc tctcttgatc ctaagaaaaa
     8341 agcaaaaaac tattcaaaag gaaatcgcca aaaagtgggc ttgattgctg ctttggctgt
     8401 tgattcggat ctctatttat ttgatgagcc tacttctggt ttagatcctt tgatggaaac
     8461 gattttccaa gaagaagttg aaaaattgaa agaacagggc aaatccatcc tactttcttc
     8521 tcatattctc agtgaagtcg agcgactagc ggataaagtc gtgatcatac gcgaaggaac
     8581 actcgatgaa gaaggaacac tcgatgaatt gcgtcatttg actcgttcga ccatcactat
     8641 agaaacagaa gcagagaata gtcacttagc acaattgaac ggtgtccatg actttgtgca
     8701 aaaaggtcac ctcgctcaat ttgctgctga taacgaagct ttcgatgtga ttttagctga
     8761 agcgtccaaa ttaggtgtga aaaaatttga atctattcca ccgactcttg aggatttatt
     8821 catgagacat tatgaaggat gaggaggaag cgaaatgact gataaatttt cacgctggtc
     8881 cacccttttt tctcaaaacc ttagccgtga ctggaaaaag atcctgatat ggctagtcgg
     8941 tgtcactgct ttttctggtg gttttgtccc tgcgtttgaa gaattgactt ccggacaagg
     9001 attagctgga ttatacgaaa ccttgcaaaa cccggcaatg attgcaatgg tcggaccaac
     9061 tccagcttcg aatgctgctg agtatacttt aggagcgatg tatgcaaatg aaatgttgct
     9121 tttttgcagt ttgtttgctg ctgtgatctc tgttttacac gtggtgagcc aaacgagaaa
     9181 aaaagaagaa cttggtctga ttgaacttat tcgttccttt cgagtcggac gtcaagcaaa
     9241 ctctttagct gtcatcgctg aaagtattct gatcaatttg cttttagcaa tatcgatcag
     9301 ctgtacgatg atttttttcc aagcggattc gatcactgca gaaggtgctt ggctttttgg
     9361 gctatctgta ggtagtatgg ggattttggg gagtgccgtt gcactgtttg ctgcacaact
     9421 gatgccaagt tcagccagtt cgaatggtct gtctttagcg tttttaggtg gactttacct
     9481 tctacgagca ataacagatg tagctgattc ctccctttcg atgtggaatc ctttaggctg
     9541 gtcttatttg acctatccat ttacaactaa caactggatt cctttgcttt atttgttttt
     9601 gttcagtcta atcttgataa tcagttcatt tgttttagag gaacatcgag atttgaacac
     9661 cggctatatc cccgaacgtg aaggaaaacc gtatgctaaa cgttctcttt tatccttgcg
     9721 tggtttatta ttctatctaa ataaagggat gacaatcagt tggcttatca cttttggttt
     9781 gatgggggcg gcatacggct ctatctacgg gaatatgcaa cagtttttag aaagtaacga
     9841 cttaatgaaa cagatgttta tccaatctgg cgtctcaatt gaaaaaaact ttacaagcac
     9901 gatcatggta gtcttgattt gtctagctgc tattttacca attgctagca tcaatcgttt
     9961 atttacagaa gaaacccacg gacgtatgaa tcagctgttc gcaacaaaaa tttctaggaa
    10021 ccaactttat tggaccaata tgttactagc tattctattt gctatattgg caatcctgat
    10081 tagttctggt gcactagggc tttctgcttt ggcttcgatg aaggatgcga aagacatgga
    10141 tctattgatg tttcttaaag ccgggttcaa tttcctgcct gccgttttag tgtttatcgg
    10201 aattagtggc tttctattcg gatggcttcc tcgaatcggt aaacttgctt atatctactt
    10261 agcttactcc tttgcactca attactttgg cggaattttg gatttaccag aatggttttc
    10321 caaaacagct gtccctagct gggttccacg gatgccaaac gattcttttg atctttccgt
    10381 gttccttacg ttatcatgta tcagccttgc actgttcgtc cttggttcta ttggttatag
    10441 gcgaagagac ttactagaag gataataaaa aagcatgtac aatttcatgc tagcctccaa
    10501 atctgggtca aaaatccaac atttggaggt cattttttta tttacaagtc ttctaactgc
    10561 tctttatcaa tgatccagac ttctcgattc tttcttttta cataaccatt ctcctctaat
    10621 aatttaaatt ttctagataa agtttcgggg gtcgtaccga taaatgcagc aagttctttc
    10681 attttcattg gcaggaaaaa gtgatccttc cctgtcgctt tagctaagtc aagcagatag
    10741 acagcgactc gttcttctac tttttccatc atcaaaaaag ttgtctgctg ctgtactttt
    10801 gttaatttct caacgttgat tgctaaaagt ttcagactaa gggcgggata atgcagtaag
    10861 agttccgaga aatctttttg tctcaatatg caaatttccg ttttttctag tgcttcgcca
    10921 aataaagact catttggaac gcctagcaac tggctctctc cctcatatcc gcccggctct
    10981 attactcgta aaagctgttc ctttccgcta gcagataatt gatacacttt catactgccg
    11041 gaggccacga tcactaattg aggttctcca ttcggcgcaa gaatctgttc tcctttttcc
    11101 acatagtgat gtttgacaag tgcgtgtact ttttcttgat cttgctgtac taagtgattg
    11161 aacaaaggaa caaatgaaac acataaatga tcatgactca taatctctcc tccttctaaa
    11221 cagctatttc taataaagaa acataacttc ccttattcca actgataatt ttcttttatc
    11281 atagcataaa cgtcaagcga accagatacc agcaaataga gtggatttct ttttgtccct
    11341 tgctttattt tccttctttt gagaccttaa gtaattgatt cctatcaatt ttttaaatat
    11401 ttactttttg aataatcaaa aacaaacctt cactcgcaag ccgagagtaa ggtttgtttt
    11461 tcgcattgct tatttcgtgt tgtctattga aatttttccg cacctagctt ttgatatagt
    11521 ggtgctagtt cttgtaaggt ttcagcggtt atttgctcaa cgtgttcgat ttcttgcgga
    11581 tagaagaata gtttacccat ttgaaaggtt cggtctctca tcgctttttt caactcttct
    11641 tgtttctttg tatcggacaa atagtcagac aaagctaagt ggtcgtcaag ttcatgttct
    11701 ggttgcggcc atatgtaata atccttgata tcgactgttt tgctccactc tttcagtatc
    11761 gcaagcaact ggttatacgc tgcaatgcta ccatatcgtt cttcgctttt ataatgttgg
    11821 tacatcaaat agatttggta ttgtttttga ttcaacaaaa ctgctagaca ggcattctcg
    11881 tcttgacgag attcgcttcg gtacgcgctc caaaaatgac tgcgtaaatt ccagccattc
    11941 gtccagcttt cgattttagg tttgctcatg ccgtacatat caggcaaaag tgcagctgtc
    12001 tggagctgaa tctctttcca tttttgccag tgttctttat attctttctt gatttgttca
    12061 atcttatctg ttggatggct ctctttgagc tgtttgaatg cgtagattgg tcgatcaaac
    12121 aactgataat ctgattttcc aagttccatt gtttcgcctc tttccgttat cttttgtatt
    12181 ctacctgaat tttgcgatat ggacaaatag aggttgtgaa aaagctgttc tgcatcaagt
    12241 cataagaaca gccaaacaaa aaactgcgat gagcatcacc gcagttttat tgaacttaag
    12301 gttgattgat cacatctaaa agcgttgaaa ataaaatggc actagaagca gctcctgggt
    12361 cgatatgtcc gattgcacgc tctcctagat aggaagctcg tcctttttta gctaccaaga
    12421 ctttggtgtg ttcttttgcc tggtcaatga tttcttttgt taaattccct gccttcaatg
    12481 cctctgtgac tggcagccaa acatctaaca tcgttttatc gtcagcttct gcctttcctc
    12541 ggctttgaat acccgctgtt ccctgctcga tcacttcgcc taatttttct tgagaatcaa
    12601 tagaatcgac ctcttttgtc gctttcatca tgttcatgaa tgcagatccg tataacggac
    12661 cagaagcccc accgactttc gatatcatcg ccatagagaa tactttgaat gtatcgctga
    12721 ttgtttcagg atgatcggct tgaaaagctt cttcataagc tgaaacccct cttcccatgt
    12781 tatttccatg gtctccatcg ccaatcgggg tatctagatc actgagatat tgtttgttct
    12841 gattgattgc ctctgcaaat tgcgtgagcc attcttggat ttcttgaacg gttagtttca
    12901 tattatcacc cttttatctt gagatttttt accatgaaat cgtctgtaca ttgctttcta
    12961 aagaatcttt ccattgtgtc tccgtcaagt cgatcagtgt tagagaaaga ccttgcatat
    13021 ctagtgaggt cataaaatta ccgacttttc ggaaaactac attgacgcct ctttcttcca
    13081 acagagctaa aacatcattc atgaacacga actgttccat caaaggcgtc ccgcccattc
    13141 cgttgactag tacacctgct tcttttggta aattcgagta atcatctaaa atcttagtaa
    13201 caagttcctt tgccagtact ttagaaggct gcatcttttc tcgacgatag cctggctcac
    13261 cgtggatacc aacaccatac tcgatctcat cttctcctag ttcgaatcct ggtttcccta
    13321 cttctggtac agttgctgct cgaagcgcta gaccgatcgt cttagttgcc tgtacgacct
    13381 tttctcccag ttctttcaac tcagctaggg aagcaccgtt tcttgctgca tcgcccacga
    13441 ttttgtgtac aaggacagta cctgcaactc cgcgttttcc agcagtatac gtactatttt
    13501 caacggcgat atcatcatct acgatcacac tttctacttc aatatcgtcc atagcagcta
    13561 attcctttgc catatcgaag ttcaatgcat cccctgtata attcttaacg atcagcaaaa
    13621 ctccttttcc actatcggct tccttaatag ccgtctgaat ctgatctgga gttggagaag
    13681 taaacacatc accaagcacc gctgcactta acatcccttc ccctacaaac ccggcatggg
    13741 atggttcatg tccgcttcct ccaccagaaa ccaaaccaac ttgttccgct ttctgattct
    13801 tggctacaac acgggaagat tctacacgat gaacaagttc tggatagctt tttactaatc
    13861 cttccagcat ttcttcgaca atattgcttg gatcattcat gatttttttc aatttattcc
    13921 catcctttct ttccggcatt ttgtgcttct gttaagattt gctgagtatc atctgttata
    13981 ccggcagtga tggctgctgc aaaagctcct tccactaaag gcgcatccac cagatgataa
    14041 cgttgctgct gctcttcttc caacatgtct tttgccagtt ccgagttcaa taccgcgcta
    14101 ccgatatccg caaaaacaaa ataactagct gcatcgcttg attcattgac tgcttctacg
    14161 attttcatcg ggtctgatcc gatctcgcca tttattccgc cgagagaaaa aatttgcacc
    14221 tcttcggatt tttgcatctg ctcaatcatt tctttaatac catctgttac tttttgacta
    14281 tgagaaataa gcaaaatact ttttttcaca agaatcttcc tttcttttac atagttgcta
    14341 acgattggtt tcgctttcat taatgaacaa ttcaagtata taataaattt ctaattttgg
    14401 gaaaatatgt gtagtgcttc ttgaagtttg ttatacttta attaaaagag aggagtgatc
    14461 gaatgattac aacaacaacg aacagtgtag agggaaaagc cgtagtagct tataaaggga
    14521 tcgtttttgg tgaggtcatt actgggatcc atgcatttaa agacttggag gcggggttgc
    14581 gaaatatctt tggcggccgc tcaaaaagct atgaaaacga actaatgggt gcaagagaag
    14641 aagcacttgc cgaaatggcc gaacgtgcaa aagcattagg agctgatgcg atcattggcg
    14701 taaaaatgga ctatgaagta ttaggcagcg acaatggcat gctgatggtc acatgtagtg
    14761 gaacagctgt ctccacgaga taagtagggg acatctgttt taataactaa agagagatgg
    14821 gacatgtagt ggcactcaag aattagattt ttcagtctaa cttcgaggta ctctaccttc
    14881 ccatcctctc ttttttattt ctttttgcgg atgattccgt aagctgctgc gactaacaca
    14941 cccgcccctg ctaaggaata actgacagaa gctgtttttt catttgtttt tggcaaagtc
    15001 tgacttgttg atttggatgg ctctgtcgtt tgctgaactg tttctgtcgt gcttccagag
    15061 gtcactgatt tttctcctgc cgaatgcaaa atatctttta ttcgttggaa actagctgct
    15121 aagtcagctt tttttgcttc aaaatcatta gcaactgttt gtgcttcgct gatctttccg
    15181 tggattgctt gactggccgc tgtgatatcc gcttgagttt gacttagctt tccagaagct
    15241 gtttgagcaa cctgatttaa ttgctgattg aattcttttg cttgttggat cttcccgtca
    15301 agatctgttt ggacagcttc cgcttttgct ttcgcttcgg caagcttttt ctcaagttgt
    15361 gcacggtcat ttcccacttt atttttaaga tcagctaaat cttgatcgat tgctgcttgg
    15421 tcttctttca atttgttttt tgcagcttct aatgcttctt cgagttcttt tcttttattt
    15481 tccaagtctt gcaaatgatc gatttggtca gaagaggtag aactatttat tgatgtatct
    15541 tctgaagatg aaatcgtttc tcctgaatta tctgtcggta cattggaagt catttctgtt
    15601 tccgaggcac cgttttcagc accagaagag cttatggttg ttgaaggttc tgtttgagca
    15661 ggttcagaag tttccgcaaa agctgtctgt cccaataaga aaatactgga aacagcaatt
    15721 ggccagatta acggcttcat tctttttttc atcacttttc ccatccttac tactttttaa
    15781 ctaatttctt attataagca aaaatgtttg gaagaaccat aaacacaaca ggctgtttgt
    15841 ctaaaaaacg gtgcatcttt tatttttttg tacgttccgg gcttttccat gtcccgcttc
    15901 cataacctaa aatcgttttg actgctggaa tgaaagtcgt cacgatcgtt atcgcgttca
    15961 ctatccagaa caaaagcata tatagtggtg cgaaaagaag gtatttcaat tttcttcgtc
    16021 gatcatctac aatcagcgaa gctagcaact ggaaaaatcc tgcgaccatt tcaaagcaga
    16081 tgaacacaaa actgaatgta aaagtaatat aaatctgttc gtagtttcct tgatatacat
    16141 aatgcccgat taatccagca aaaagaacta cggaaataca aaagaatatt gaccagacaa
    16201 tactcaatgt ttgatcaatg aagatgatcg ttcttccaat atgtttaaaa ggatggagca
    16261 tcactttttt gaaattcgtc agccagactt ctgttccacc ttttgcccaa cgttttctgt
    16321 gtcgatatag catcttcaac gtcacaggta cttccatgaa aaagataatc tcaggagcaa
    16381 aaacagataa ccagtcattt aactgatgat cccaagcaat actgatgtct tctgtcgctc
    16441 gatcttgtct gaatccgccc acatcgatca aggcttcttt tcgatacatc gtatttgctc
    16501 cactgtacgc ataaagacca ccgaaaacag ctgactgtgt tcgtttaatg atgcccacga
    16561 tacttgagaa ttcaaccgtt tgagattttg caatcaattt ggtacgattt tggacatcca
    16621 tatttgcagt gaccgcagca atatgtcttg caccagggcg aatgaaataa ttcacatacc
    16681 taatcagtgc atctggctcc ggtaccgtgt ctgcatcatt gcttaaaatc aatttccctt
    16741 ttgcaaaggc aagtccgata ttaaacgcgt gggcttttcc tttatttttt tcgatccgaa
    16801 ccacacgaag attagcgtat tttttcatca gtctagctaa tatttctggt gtttggtccg
    16861 ttgaaccatc gtctgtcact aatacctcat agttgtgata attcaatttc gtcatcaaat
    16921 actcgattgt atattcgatc acaatttctt cattatgggc tggcaccatg atcgtgatga
    16981 acggttcgac actcaaggga acatctaccc attctttttg cttatgtttg tataaaaaca
    17041 cataacacca gacaccaata aaccatacaa atccgcctaa aatcggataa gaaacgagaa
    17101 aaaaatacat aatagacaaa caagtatcta agaataaatt acctgtatgg gtgattgaga
    17161 tcatttcagt tccaccccat tttctttata caaatctgca atgaatgtcg tatctagatt
    17221 tttctcttcg gagacagaat aaaaacggac cgtttctctc tcttcttttg ttccaaaacg
    17281 ttccgtatac acttcttcaa gtaattcttg tctttttttc aatttttcat cttcatattc
    17341 aaaagattta tttacttttt tgtatagatt tcgattgttc cacctagtca atacaaatga
    17401 ggtaatcagg aaactgaaaa aaatcaatac aaaaaagccg attaagaaat acagcatttt
    17461 cttttctgat aaaaaagcgt acaaggaaaa atccttggct ctttctggtc tcgttaatgg
    17521 gaaaaagacc catataaaag gaagaacaac gatcatccat cctaaaagag ccactaacgt
    17581 ttgccaaatc tttaaccagt aattaccttt tgaaaaatac ttatctttca ccaaaattga
    17641 tgcaacttct tctcttgtta cttttttcat atcctcacct cacgtttttt tgttacgacg
    17701 taggagttta ccatacattt catttctttt cacataaagt gttcctaaat ttttcctaag
    17761 aaaaagaaca aaacatttct catcagcaaa tgaaaaatat tttgttcttt ttatcagttg
    17821 ttctttttat tttttatctc ttaattatgt tgctctttcc aatacgacaa tgcttttcat
    17881 tcctctagat atcgccgtgt acatttgtct gcgtcttctt tgctcatctc catcgttttc
    17941 aaatggatat aagattacat gatcaaattc cagtcctttt gctagactca aaggaatgat
    18001 ttggcagttt tctaatccat atgaattttt tttaatcgat tcttgtagcg tttgggtttc
    18061 ctcttctgtt tgggtgataa ctgccgcttt ttctcctttt agagaaacca aaatctcagc
    18121 tagtattttc aacaattctt cagaggatcg aaaagagcgg tattcgggtt cttttccttg
    18181 cggtcggatc gatacgatgt cgatcttctc ttgatccaca gcataggttt tgaaaagctc
    18241 tgtgattgct ccgctagaac ggtaactatt tctaagatca taccgatgga tcggcagatg
    18301 gtagtcgtcg aaacaacgca taatatcagc aaaagtagtg gaagaattaa agattgcctg
    18361 attctcgtca cctactaaag taaagtgagt ttttggaaat aattcgatca atagacctaa
    18421 ttgtgccagg gtataatctt gtacttcatc aatcaataga tagcgaaatg ctggtacatt
    18481 taccttttca acaagtaaat gacgaatagc taatataatg actgcttcat caacagtacg
    18541 tgtgggttgc caagcataag ctgagccata tcgtttttca taaattcttt caaacaactg
    18601 atgctcatcc acccatgcca tttcttcgat ttgtctggtt atttttcgat attttttttg
    18661 taaaagtttc cttgcataag ctacaatact ttgttccgaa tcatcagaaa tcaatttacc
    18721 gaataattcc aactgcctat cttctgtcaa cgagagtacc tgattctgca cagcaggact
    18781 ttttgcttgt ttcaaaagat gattcttcca ttcgctcatc agtgcctttt tcgttgcttg
    18841 aagcctatcg atcaatttag gatgagcagg aactttctca tatatttttt cgatcgtttt
    18901 tttagaaagg actgtttttc catttttagt aagtccacgg ataaaattcg gatgatctaa
    18961 aaacaaagga tctgattgtt ttagattatc gataaacttt ttgctacgca aacgttctgt
    19021 ctgctccgat acattttctc ccgtgatacg tttgaaataa gcctcttcac cttctatttc
    19081 ctctgctgaa agctgtgaaa ccagctgtat gatggttaga ttcagtggat ttctttcacc
    19141 taatgatggt aggacattcg aaatatagtc gataaaccga tgattaggtg atagaatcag
    19201 caagtcatcg gatgtcatcg tatctcgata taaatagagc agatacgcaa tacgctgcat
    19261 gatagcagag gttttaccac ttcctgctac gccatttacc aagatatttt gacttttcac
    19321 atcccgaatg attgtgtttt gttccgattg gatcgtagca gtgatagcct tcatttcatt
    19381 ggtctcatct tggcctaaga cttctaataa tacgtcatct tgaatagcta cagacgtatc
    19441 aaaaaacttg accaaacgat ctctttccaa aagaaattgt cgtctttctt taataaccgt
    19501 atcgatttta ttttgacgaa ccgtataaga agatggacca atcatgttat tgtaaaaaag
    19561 ttcggcaatt ggtgaacgcc aatcataaac aagattttca tctgcatcat ctgtgaaatt
    19621 tgctgtaccg atataaaagg attcttttgg ctcattatcc agaaagtcta caacgacttt
    19681 tccaaagtag ggacttttca ataaacgttc gatctttgct agctgatttt ctgcgttttt
    19741 ctgtttgata ttcatctgat cgatttctct atttttcatt tcaatcatcg aaaaagtatc
    19801 caggttatct aagtaactgt caaaattcaa tcgaagctcg ccagccattt ctttcaacga
    19861 ctggtttcct tctatttttg ccgtatccat cgattcccgc agttcgtttt ttttatcaat
    19921 tagcttttga tacacgttct tcagatatgc ttcttctaac tgtttttgtg tgttgaccat
    19981 acacattctc ctcttttttt aaagtggtgg aaccgattag tttacctctt ttaagagtcg
    20041 aatgcaagct ttttaacgag tatcatttgt taggatatat cagttcttca ggtcggacag
    20101 tttgatataa agaaaatgca ccatcaaggt tttttacgtg gtagccagac tgcttcaaga
    20161 ttctttccgc tagatagcta cgtaatccgc tatgacagct gacgatatat tcttgttggc
    20221 tgtctaattc atttaatcgg tcccgaagtt cattcaaagg gatatgtttg gcttccttga
    20281 atttgccctt ttccaattct tctgctgttc gcacatctaa taaaattttt ccttttgcta
    20341 gttctgtcgg caattcatgc cattgtacgg tttcactaag cccttctgca atgttcattg
    20401 ctgcatatcc tagcatgttt actggatctt tggctgagcc aaatggcggt gcatacgtca
    20461 attctaattc cggtaaatcg aagatcgtca aatgcccttt gattgctgtt gctaaaatat
    20521 cgatccgttt atccacacct tttgccccaa caccttgtgc accataaatc tcgccagtct
    20581 ctggatggaa gatcaacttc agtaaaatat ctgttgcttc tggataatag cttgcatgat
    20641 cttttcctga tacatgaatg acttcaaaag acagttcgtt ttctttggct gttctttcac
    20701 ttaaaccggt ggatgcggca gtcattccaa acgttcgtat aattgctgtt ccaataccgc
    20761 cttgatttct tcgagaaatt ccggaaatcg tgtccgcaac ttgtctacct tgacgattgg
    20821 ctggtgaagc aagagaaata agtgcatctt ttccagtgat ttgctgtttt acaacgatag
    20881 catcccccac cgcataaata tcaggaatat tcgtttgata acgttcgtct actaggatac
    20941 ccccgcgtat gcctaattcg attccagcgg tcactgctag ctggttatca ggacgaacac
    21001 caatggataa aataactaaa tcagcaggga tggtacgccc atcatccagt cgcaatcgtt
    21061 tcccgtggtc ttcaaatcca gcgacagcat gagaagtaat cacttctact ccttgatgag
    21121 acaattcttt ttctataaaa gctgccattt cttcatccag tgttggaaga atatgtggtg
    21181 cttgttcgat caccatgact tctaaacctc ttctttttag gttttctgcc atttccaatc
    21241 cgatgaatcc tgcaccaacg atcacggcac gctttggctg tttttctaat gcatgcatca
    21301 ctttatcgat atctggtaca tttctaatag aaaaaacatt gtcggcttct gttatccctg
    21361 gaatcgatgg aacaactggt tttgcaccag gagataaaac caatgcatcg tactgttcaa
    21421 tgtgtttttg accctcatgt acgacttcta ccgttttgtt ttcgggaaag atggctgtca
    21481 cttcatgatt tggacgcaca tctaaacaaa aacgagcgga taatgattct ggcgtttgga
    21541 caagaagatt ttcccgttca ctgatttctc ccgaaagata ataaggcaag ccgcaatttg
    21601 caaaagaaac atacggtcct ttttcaaaaa caacgatttc tgcatcttcc attaatcggc
    21661 gaagccgtgt agcagcagac attccacctg ctacacctcc gacaataacg attttcatct
    21721 tatttccctc ctactgttcg atcaaaccat tgattcatgc caccacgtac attcactaca
    21781 tcataaccag atttctttaa ttctttagct gcttgtttac tcctcatccc tgattgacaa
    21841 atcacataga cggtcttttc tttgtctcca tcatatctgt ttatactttg taatggaaca
    21901 tttttagctc cttttatatg cccgccccgg tattctgcag gtgttctaac atcaagtaac
    21961 gctggatttt ccaaaagctt ttcctttaat tctgggactg ttatcgattt tattgattga
    22021 aatagcaaat tcattttctg cacctcattt acatttttat aaatacctca tggggtatat
    22081 taaacaggag ctttattaat atgtcaacca gaatgactct tcattttttt cactactttt
    22141 tatatttgca taaaataccg ataaggggta ttatctaatt ataaaaatag aggagaatgt
    22201 gttatggaga ttgataataa aaatatcctg aaccgtttga aacgtacaga gggacaaatt
    22261 cgtggtatcc aaaaaatgat cgaagacgaa aaagaatgta tggatgtcat cactcaatta
    22321 agcgctgttc gttctagtat tgatcgcgta atgggcatga tcgttgcaga taatctgaaa
    22381 aattgctttg agaaacctga tagtaatcca gaagaacaag cggctaaact agaacaagcg
    22441 atcaagatga ttattaaaaa gtaaaggaat gatttcaatg aaagtcgttt tccatattga
    22501 tgaattagaa aaatggtcag aaacagggaa aaacgtaaaa aacctgataa aagcttctcc
    22561 agaaacgacg attgtcgtat ctgtaaatgg catcgcgatt accggttatc tagactctgc
    22621 caatgcagaa ttcttagatt tgcaaggagt cgtttttcac gcttgcgcca atgctatgcg
    22681 tgctaatcat atttcagaaa gttctttacc tgaacaagta atcgttgtac cagcaggtgt
    22741 ccttgattta gttgaactgc aatcccaagg ttatgcttat atcaagcctt agtcagtaga
    22801 ggttgcgaca gaagtgatca gcttcaagaa atttcggctt atttttcgaa gaagctactt
    22861 ctggaaaacc gtgaatcaaa ggttgtgaaa acgctgtcct gcatcaagta ataagaacag
    22921 ccaaacaaaa atagcttctc atatttttcg tttggttggg cttattaccg cagatgcaag
    22981 cttttgaaca ccgtttaagg aagaggttgt gaaatcagcg gtttgaccta agtattagag
    23041 aaaaaaacgg gaaaatagct cctcatattt tgccgttttt tgagctaata ccgaaggtca
    23101 gctgattgaa caccgtttaa ggaagagatt gtgaaaaagt cgcttagttt cgagtattaa
    23161 gaaaaatttt gtgaaaatgg atttctacat ttttgcataa atttggctta ataccgagaa
    23221 actggctttt gaataccgtt taaggaagag gttgtaaaat cagcggtttg acctgagtat
    23281 tagagaaaca aacggaaaaa tagctgctca tattttgccg ttttttgagc taataccgaa
    23341 ggtcagctga ttgaacaccg tttaccaaga ggttgtgagc ctaccattta actccgaatc
    23401 acaagaaata atttcaaaaa caacttctcc tgtttttggt tcggttggct tattatcgag
    23461 aagtagctac tgggagtcta tttatcaaaa aaaggaatgc gacataggtc acaccccttt
    23521 tttattttct ttgaaacatc tttcggtact cgacagcata caagacaaaa gattgtaaaa
    23581 gaccgtaagt gatgacggca aaaatgactc tcacccacag cgttggtaat tctgggaaaa
    23641 gcagcaaaag gatcatgcca acatagatga cagcagtcgc tactttgcca taccacttcg
    23701 ctccacttaa tttgatattt ttagatagcc cgattaatcc agctacaaac ataaagcctt
    23761 cttttatcaa gaatagacca aacaacagcc aaagccacgg tcgataccat gccatagaca
    23821 aaatcagaaa aagttgtgtc aatttatctg caaacggatc aagcaccttc cctaagtctg
    23881 ttacctgatt atatctccga gcaatgaccc cgtctagata atcagacaaa cctgagacaa
    23941 caatgaccgc tcctgctata taaaatgact gtctcagcac aaaataaaga taaatcggca
    24001 gcaaaaaaat acggaatatc gataaaagat tcggaatcgt ttgtatttct ttacgccagt
    24061 ctgtgcttaa tttcatttta tcgccctacc tcctcagcac tcttttcttt ttattttagc
    24121 ttacacgggg aataaaacca atgatttcac tgtttttatt tttctttaca gacactgata
    24181 ttatgagcta atttgagata atcacttgct gttttcatcg tttactcttc tttcttcctg
    24241 tcgtttgcgc atttctttta ctagtacttt atgagctttt tttgatcctc gctctaggtc
    24301 acgctgccgt ttacgtgttt tataatcgat aaacagactg tctaaatcgt aacctgtcgg
    24361 gtacagatct tctgctgaac gcaccagacg aacacgctga cgaggcacgt ggattatttt
    24421 tttgtctaaa tatacatcaa tcgtatcttc acctatatct tcataaacta acgcttcttt
    24481 ttggtattca ttgacaaata tccgatcacc ttttgcaaag agctgacgtt cttttttatt
    24541 ctccttccta tttgtaactg ctgtcttagg aagaaattct tttttctgtg tccgataggc
    24601 tttttccgcc aagtaacgct ctgcttgatg gatcaatttc atcgacatat ccattttatg
    24661 agcaatccac aaagcttggc tttctcctgt ttcttccaac ccgcaactga tatttaggac
    24721 gaagtgcttc ccgatcgaaa gccatagcag ccggcacaaa atcttcatga tctccggcga
    24781 atttcttgat ttctccataa tgggtcgtgg caatgatcaa tgccccttgc tcatacatag
    24841 attccatgat tgcgatcgct agtgcagccc cttcatttgg ctctgttcca ctgccaatct
    24901 catctaaaag taccaacgta ttccttttta tctttttcaa aatagcagcg atgttttgca
    24961 tatgaccaga aaatgtactc aacgcatttt ctaaattttg gtggtcaccg acatcgacga
    25021 aaatctcatc aaagacagca agctctgtcc cttcttttgc cggaacttgc ataccgaaca
    25081 tcgccatcaa agtcaataaa ccgactgtct tcaacacgac tgttttgcct ccggcatttg
    25141 ctccggtgat aatcaagcct cgatagtctt taccgatttc aacatccaat ggtaccgcat
    25201 gctcaggtaa aaatggatgt ctgccttgct tgataatgat atgttccgat ttattgattc
    25261 taggtgtgct tccattgatt tctcggctaa attttgcccg agcaaagatg atatctaaca
    25321 ccgtgatcgt ttcgatcaat aaatcgatca cttcttcgtt ttctgcgata gcaccagtca
    25381 atgccgccag gacttgatat tcttcactga tttcttcagc ttttaacaac tgatagtgtt
    25441 cattcaattt agaaatcaca gttggttcaa taaaaaccgt cgttctttta tttgattcat
    25501 cgataatcgt tccatctatt ttatttttat agctggcttt gataggaatc gtatagtatt
    25561 cgcctttttg aacaatcatt gcttcttgga tcatttcttt gtttttcgga tgacgcaaga
    25621 atttcagtaa ttttgactgg atttcttttt cgattagttg taattgtttg cgtactttac
    25681 gcaaattacg tgacgcgtcg tcactgactt tattattttt tattttctgg tcaatcaact
    25741 cttctacatt tatcaaatca ggaagatgtt tgctataagc aaacaacaag ggtgtctggt
    25801 attgattctt atcaaaaaac tttgtgatca tccgactgct tctaagaaaa tccgcatatt
    25861 cgatcaaatc ggttggctgc agaatcaacc cttttttgac ttgttctgtc agtgcatcga
    25921 tcctcggcaa ccccataaat ggaacatgct gactgctttc taagatcaag cgtgcttctc
    25981 ttgtttcttc ttgacgatcc aagacagttt gtaggtttgt cgagaccgtc atatcgctga
    26041 ttcgtttttt gctatagttt ccaattgctc ttgcttggat ttcctttttg atccgatcaa
    26101 attgtaattg actaatcatt tcgttgtcca tattctctcc ttttcttgaa gagatacctg
    26161 tcccaaaata aataagggcc tagagataaa taaaaggata gaacacagct taaaaaagtc
    26221 atgtcctatc cttattagaa tacaaagata ttgttttcct gacaggtacc gtttcataag
    26281 cacaccaaat aaactttgtt tattggctat tcgacttact gattagatac cagctacact
    26341 cacaaaacat accccattct tctaggtctt atttattttc cacttaacta tagcaagaca
    26401 cattttggtt gtcaaacttt agtatgtttt atagatttac accattaatg aatagacacc
    26461 taccgcgata attgctccga tcattggacc tgcgattggt acccatgaat atgcccaatc
    26521 tgaagttcct ttattagcta ttggcaatac cgcatgtgct aatcgaggac caaagtcccg
    26581 agcagggttg attgcatatc ctgttggccc tcctaatgaa agaccgatgg ctaagatcaa
    26641 tccacctaca gcgaatacgt tcgttccagg tgcaaattcg ttttgtccaa aagctagcaa
    26701 cccaagaact aatacaaatg taccaattaa ttctgtgatc acatttgctg gataattccg
    26761 tatagcagga cctgttgcaa acgttcctaa aatcgcgctt tcatctttcg ttgcattcca
    26821 atgtggcaaa taagaaagcc aaacaagaat ggcccctgca aaagctccta aaacttgcgc
    26881 aatgatgaaa ggaacgacaa gattccaact aattgcccct gtcatcgcca tagctagaga
    26941 gactgcagga ttcaaatgag ctgggcccat gaatccagaa atatagacag ccattgttac
    27001 agcgagtccc caaccaaatg cgatgacaat ccagccagaa gcctgtgctt tacttttgtt
    27061 taaattcaca gccgcacaca caccatctcc aagcaaaact aggatcagtg tcccaataaa
    27121 ctcccccatg atttgagtca tatcactgtt catttatttc tcccccttta gttcccgcag
    27181 atctgattct gcaatcaatg cttctaaacg tttagtctgt tgcgccttct cctcttctgt
    27241 ccattcaaaa tatccagcaa ttgcatcgat cacaggttgc ttgatctcat caagctgatc
    27301 tcgttcaaac aacagatgat ttgtacgacg aatgagataa tcgcctgggg ccaaaaccat
    27361 ttcttcttct aaaccataac gtaaccgagc tgactcagcg agactcaaac caggataagg
    27421 tgccatttct tttgctaatt caaagatacg tcgggcatta gtcccgtaaa aatcagcgat
    27481 ataagtagca tcttcttcct ctaaaccggc tgctactcct tcttttgcta attctgtcac
    27541 tgtttcttct aatttagttg gatcgaagtt tccacctgaa atctgatatt ttttagagtc
    27601 gatttctttc gtctctattc cgtattcttc ttttaataat tggcgtatca atcgcaaagc
    27661 tccttctgcc atcttacggt aatcggtgat tttcccacca gataaagtca gcaaaccatc
    27721 tggttctctt tctaaagaac tacctctgga aatcgtagaa ggtgcttttt catcacggct
    27781 gttttccaaa tggttcaaca cgtcttctac ttcagcacga gaaactttgt tttccttata
    27841 ttcacttact gtatcgacaa ctttattgaa gctcttgtct gaaatcgatc cattatctcc
    27901 accattgtaa tcagaaccag aattaccaat caacagtgga cgaagtcctg cccagcttgc
    27961 ttcgatatca ttcaatgtga tatttgcttc tggatagcga tgattgatca catccaatag
    28021 ataatctaca tcttcttgtg tgactttcgg atccgtaaaa tctccttggt aatccgtatc
    28081 tgtcgtacca aagtaagtct tgttttctct tggaatagca aaaaccatcc gcccatcttg
    28141 ctttcctgta tcgaagtatg tgggttgcgg tacaggcagt tttttcgcat ctacaactaa
    28201 atggatccct ttagttggac gcattttagg agagactgga cgcgtaaaat tcaagtttcg
    28261 tactttatct acccaaggac cactcgtatt gatcactaat tttgctttga tttcgatcac
    28321 ttcatctgtc agcaggtcac gagctttgac gccaacgatt tgatcgccat catataaaaa
    28381 gccaaccgct ttcattttac ttactagata agccccatct tcggcagcct ttttgatatt
    28441 atcaatcact aaacgggcat cattgttgcg gaaatctaga tagacacccg cgccttttag
    28501 cccttctttt ttcaaaaacg gttctctttc caatacttct tctggtgtca gcgtataatt
    28561 ctcatatttg gttcctgtca catttgccag tttgtcataa aggtccattg ctactttgac
    28621 cgagaacata ttgaaggttg ttgctccttc gccctcatag attggcaaaa gcattggatc
    28681 tggttttggg atgtgtgggg caatactttg tacgactgca cgttcaccaa ctgtgtcagc
    28741 tactacttcc acatcaaatg tcttcagata acgaataccg ccatgaacaa gtttggtcga
    28801 gcgagaggaa gtcccttctg caaaatcctg catttcgatc aatcctgttt tgattcctga
    28861 tgctgctgac tggactgcca caccggcacc agtgattccg ccaccgatga tcaacagatc
    28921 caattcttct tgctgcattt tttgaatgct atcttgtctt gtcttgtttg aaaacatatg
    28981 gatttcctcc ttattcaaat gcttgggtag cttttactgc ttttttccaa ccgttgtaaa
    29041 gtttttctcg gcgctcttcc tccatttgaa cttcaaatag cttgccagct tcataaaatt
    29101 cgcggatctc gtctgtatct ttccaataac cgacagctaa tcctgctaaa aatgctgccc
    29161 ctagcgccgt tgtttccaag ttttctgctc gttggatcgg tacattcaag atatctgttt
    29221 ggaattgcat cagatattca ttgtttgctg caccgccatc tactttcaat acaggaatct
    29281 tgattccagt gtcatcttgc atcgtatcga tgatatctct cacttgataa gcaatcgact
    29341 gtaaagtagc tttaatgata tcttcttttg tcgtaccacg tgtcaagcca aacatagccc
    29401 ctcgtgctgc ctgatcccaa taaggagcac ctagcccaac gaatgcagga acaacataaa
    29461 cctcatcttc gcttgtagag cgtttcgctg cgtcttctga atcgctagct ttttgcaaca
    29521 tttgaagtcc atctctcagc cattgaatcg aagaaccagc cacaaaaata cttccttcta
    29581 aagcatagta aacctttcca tttatgccgt aaccaattgt cgtcaataaa ttatttttgg
    29641 ataattgcgg tttttcaccg gtattcatga caataaatga acctgtacca taagtattct
    29701 tgaccatgcc tggttcgaat gccatttgtc cgaataatgc ggcttgctgg tctcctgcca
    29761 tccctgaaat tggtgcttcg cttccataaa aatgataacc ttgcgtataa ccataaactt
    29821 ctgagttaga agtgactttt ggtaacatca ctcgaggaat atttagtaaa tctaaaatct
    29881 cctgatccca atctagctga tggatattga acaacatcgt ccgactggca ttcgagtaat
    29941 cagtaacatg tgcttgtcca tcggtcagtt tccatactaa ccaagaatcg atcgttccaa
    30001 acatcaattc gcctttttca gctcgttctt gcgcgccttc tacatgatca agaatccagc
    30061 gtatcttcgt tgctgagaaa taggcatcga tcactaaccc tgttttttcg tggaaaaatt
    30121 cttgatagcc ttcatttttt aagttatctg caattccagc tgactgtctg gattgccaaa
    30181 caactgcatg atagattgga cgtcctgtat ctttttccca tattactgtt gtttcacgct
    30241 ggttcgttat gccaatccca gcaatctgat ttggtttgat ccctgattcg atgaacgctc
    30301 cggcaataac tgactgtaca gaattccaga tttcatttgc atcatgttcc acccaacttt
    30361 cttgcgggaa atattgcgtg aactcttttt gagaactgcc gatgtgtctt cctttcttgt
    30421 caaagataat tgctcgtgag ctagttgtac cttggtcaat cgccatgata tacgttgatt
    30481 ctgtcattgt gattccctcc attatatgca aacgctttct ttaactactc ttatcatact
    30541 actgttttaa aaaaagaaac tgtcaaaatt ttattctttt tttctttttt tgacagtttt
    30601 ttattatgaa gctatttttt aatcaattct tttctttttt cagcgtctct attcttcttt
    30661 tcaatcgaat aatgtcgtaa ggtgacgcaa attctgacag ataatattca cactgttttt
    30721 tgtttctctg gcaaaatgtg atcaccaaat catattcttt accttcttca taacttccaa
    30781 tctcaatacc gccgattccc ctcagttctc tgatcagata ttgttgaaaa gcaatacgat
    30841 aaatcggcag actttctaaa tcgattccaa tcactactgg ttttgcaata taaaaatcga
    30901 tcatcaaaag aacattggca tactggatca tcaggtaact aagctcacta tcttcagctc
    30961 ttttcctcgg caattgctgc accgctgttt cctgtaattt cgccagtaac tgtgttaagg
    31021 aatgcccgag cattttctgc tgctgttcca aaagccgatc acgctcatag acttcgatct
    31081 ttccaacaaa gaaaaaccat tcattgttga tctgggaaat ttggtagcct actgcctttt
    31141 cttctttgat tttcaaacga cgaggacgat aatgccataa catcgtttcc cgaatgtaag
    31201 tatctaaaac agcggttggt aactttttgc tccgtgtcaa atcatactga taaaatattt
    31261 cttcgtctac tatcgaaaaa gaaacaaaaa agctgtaaaa catcattgtt tcgtatacat
    31321 tcagttctgc tgctgttcga ctaagatgca tcacgatgat tggatcgatt gcttgataaa
    31381 gccggtccga ctgatagagt aatttctttt ctttcaaagt tgcgtacgta cttttttcat
    31441 tcaatagtct ttttttcgta atcccgagcc agcaagcaat ctgtgcttct gctgatgccg
    31501 taaacgttgt ttctaataca cggtccaatc ctagaatgaa cggtcttttt tctggtgtat
    31561 tttgcaaaaa aagcggtcgc tgatcttccg ggatatattg gaatagttca taataaaaat
    31621 atcgtatctg tagctcttct ccgtataatt gaccgttttt gatttgtaat ccaaattcct
    31681 ctaagagctg gttcaattct ttgatctttc gaaaaacaga agactcactg atattaaacg
    31741 ctgtcgctaa tcgaacgatg gatacttgct gatgttctaa taaatagacg agcatcttaa
    31801 acttcaagct ttcctgcaat aaaaacaata gaattttttc caaacttaca tcttcgtcca
    31861 acacaagcag cgcctgatac tcatttcgct gtacttctac ttttttttcc atcattcggc
    31921 caatcaattc aatatcttcc aaatattgat caaacgaggc ttttgacagt tggacatgct
    31981 ctctcaaacc attgatagag gctgttcccc cttgcagaac aaggtttcgc aaaatcagga
    32041 tctgtaactg ctcttttctt tctaataatg cttcaatctt cataggcagt attcgccacc
    32101 tttgaccaca ccatatctgg cacacggtat tctggctgga aaaatagctc atgttcttct
    32161 aactgttcaa acgtccatcc ttcttctact gcaattgtca gttggtcaag aaggtggaac
    32221 atctcttttt tgctttggag ctgtgctcca agaatctttt tttcagaatc aaatagaaat
    32281 ttgagtttaa ctttgctttg atttattgct gtaagcttgt agtctacgta tcctgtttca
    32341 attttttggg gataaaaaat gctctcttct tctgtcaaac ctacgcttcc taagaaatag
    32401 ccaaaccact gattgccgac tggacgatag gttccctgat cctttgtctg tgagccacta
    32461 attgtcttgc tgacatttcg tgctgtacgg acagcgttat ttactagaga aacatacatt
    32521 ttttcatttg ttggacgaaa agttacttgg atcgcatcgc caatcgcata aacgtctttt
    32581 tgagacgttt gcaagtagtc atctacccag atcgttccat catcattcaa tgttaattgt
    32641 tcttcccaca tctgattgtc gggacgagaa tgattagcca gcaaaacaag atcatagttc
    32701 tcctttcttt tttccgtctc tacaatagcg gtttcatttt cggtcaaaga cacaacttgt
    32761 tcttctaaaa aaagtgaaag cccttgattt ttcatttcct ttactaacgg ttctgtcatt
    32821 tcaggatcta gataacgaaa aagaattgac tttcggcttt cgtaaagatg gatttgtttt
    32881 tttcttgatg ccaacccttc agctatttcg attcctgctt gtcctgcacc aataattgca
    32941 attttctttg cattcatgat cttttgctga agagccgtta cgttttgtat ctttttaact
    33001 gggtgaataa gcgttgattc tgcagaaata tttcgaaact tttgatttga accagtcgct
    33061 agaatcaaac gatcaaaatc caattttttt cctcctgcta aaacgacttt tttttctttc
    33121 aatcctatta ctgtcttttc tgtgtaaaca tggattcgat agcggtcagt cagttcttct
    33181 ttcgtgatcc aagaaagttg tttttcactg gtaacctttc cttttaatat caaattgaac
    33241 ccgctgggaa tccatcctaa cttcgattgc ttttcaatca aatatatttc acttgttggc
    33301 atcaattggc gaagataaat agccgcatga atccctgcaa acgacccgcc gacaattaca
    33361 atgttcatct gcattcctct ttcttataag gtgttctact gctaacttct caatcagaaa
    33421 acacagtatt cataactcgc tttcaacctt atgatacata gcgatgcagc agaatcaacc
    33481 ctctccatca taccgtgttc taggtctgct tctcaataat gtactagtgg acctaattga
    33541 agagtatcat ttctgaagag atgtttcaaa aaatgtactc ttataaaaga aaaaaactcg
    33601 ccttttacgt acctctgtcc aaataggaaa cagaaaagaa cgaaaagacg agttttagcg
    33661 tgtgtaatgt aatagttaga atagacacat catttatttt taattcttta atgcttcaac
    33721 aactgcttcg cctaattgat gagcagattg aggattttgc cctgtaagaa gccgcccatc
    33781 aatttgaacc acttctgaaa aagctgctcc agactgatag tttgctcctt tttctttcaa
    33841 agcatcttct gctaagaatg gtacttcatt cgttgtacca tttgcttcct cttcttcatt
    33901 actgaaccca gtcactgtac gtccagctaa aatagatttt ccagactcat ctgtaactgg
    33961 caacaatcct acaacaccgt gacaaacagc tgagaccagc ccttcatttc gatagatttg
    34021 tgaagcgact ttcccaagat ctattgcttc tggaaaatcc cacattgttc cgtggccacc
    34081 agcataataa accgctgcat aatcatttgc atccacatca tcaggacgta aggtatttcc
    34141 caaggcccga tttctgaaat cttcatcttc ataataggcc caatcgattt catccatatt
    34201 caaaacactt tgcggttcta aaggtacata tccgccttta ggactgacaa aatctgcatc
    34261 gatcccattt tttactaata catcataaaa atgagtcagt tcacttaacc acaaacctgt
    34321 aggacgctcg atcttttcgt acttttctac atttgttaat acgatcaata ctttcatttt
    34381 cccatcctct ttctataaaa attgcgttat tgataacgtg ctttcaagaa attatataat
    34441 gggcttggca aataaagctc tttatatgct tcttcaaaag gtttcgttac aaattcatcc
    34501 tcacggtttt ccaataattt ctctgcccag tcaggatcga cgatcatttg ctgtccaatt
    34561 gctgcaagtt ctgcatattt caatacctgc tctacatctt cgcgattgcg gatcccaccg
    34621 acaccaacta aagggatctt tccttgaatc gtgttatgga ccacttcaag aatcgattta
    34681 tcgttgtatt tatcagaacg agctattcga tcatacatat ttaatgaaac atgcagataa
    34741 tctagttttg actcacgtaa tcgttcaaga agccagatcg tgtcttcaaa acggatacct
    34801 ggtgtttcat attcttctgg tgagaaacga taccctacga tgaatggttt tttagcatat
    34861 tgttcaaccg ctgagaaaac cgttgttaat aattcttcaa taaaacgata acgattttcc
    34921 aagctaccgc cccattgatc ctctcgtcta ttcgaatgcg gagagaaaaa ttgttggatc
    34981 aaatacgtat ttgctccatg caactcgatt ccatcaaatc ctgattcaat cgctctacgt
    35041 gtggctttgc caaatgcttg gattgtttca acgatttctt cttcactcat tgctcgtggt
    35101 gtttccgcat caggacgttt tgctgcaact gcacttgcag atacaggctg ttctccagat
    35161 aaagttgctc gacttgtcat tcgtccaccg tggaaaatct gaataatcgc ttttgcgcct
    35221 tctccttgga ttgctttcgc tagctcactt aatcgaggaa tcatttcatc atgagcgatg
    35281 ctgagttcac ctggccagcc ttttccgata tcttggacat ttgcagcacc agtaataaca
    35341 gcaccaagac ctttagaacg ttgtttataa taagtgatct catcttcggt gatcactcca
    35401 ttgaaaaagc tgagttgtgt cgtcataggc gacagcatca atcggttctt caattgaact
    35461 cctgaaggta aagtaattga ttgatcaaat tgtgacattg tcattcctcc cataattcgc
    35521 tctgattaac ctatcgagaa tcatctatca ttaaaccact cgattagttg tacatgcaac
    35581 taatttgctt aaaaaatttt attttttttg taacttatct gttgcatcat tcattgtctg
    35641 ggctaattct ttacttgctt catttcccaa aactgctttg tatgactgat gaagttcttc
    35701 ccagctacca tcgacttcct tagcaaattg gcgtccttgt tctgtaagat aaactaatga
    35761 caagcgacct tcgctaactg ttttgacgta tcctttatat tctaattttt caacaaaacg
    35821 agcaatcgtt gatggggcgg aatagagcat ttgtgcaata tctttttgtg gtattccatc
    35881 tttttctttt aatatcaata aaataaaacc ataagttggt gccagacctg tccttctaaa
    35941 cgcttcatca gctaatttat tcaacatgcg atctagcttt ttcacgctaa agaaaagaca
    36001 ttcatctaac gctttttcaa ttggcttttc catttcatcc cctccattgg cgtacatatc
    36061 atagtatgat ttttattttt tgtcaaaaaa cacggaataa tgtccgcctc ctctgtctag
    36121 atttgaaaaa aagaagtagc catcttcaaa gaatttcggc ttgttttcga caaaactcct
    36181 tctggaacac cgtgaatcag aggttgtgaa aaagtcgttt agttttgagt atgaagaaaa
    36241 attttgtgaa aatggctttc cacatttttg cataaatttg gcttaatacc gaaaaaatgg
    36301 cttttgaaca ccgtttatat cagaggttgt gaaaaagccg tcctgcatca agtaataaga
    36361 acagccaaac aaaaatagtt cctcatattt tgtcgttttt tgagctaatg ccgatggtca
    36421 gctgattgta caccgtttat tgagaggtcg tgagcctgcc gttgaactcc gagtcacaag
    36481 gagcaatttc aaaaaacagc ttctcatgtt ttatgactat ggtgacttgt gatcgaggag
    36541 ttggcaggag aatactgttt attcgtaaag aaggggctgt gacaagactt ttgtcacagt
    36601 cccttatttc cttttattat aggatttcgc catttgattg gatgacttgt ctgtaccaat
    36661 caaatgattt tttctttaac cgtttctttg tgccattccc ttcgtcatct tgatcaacat
    36721 agatatatcc ataacgtttt gacatttgtg aagtagaagc gctgacgata tcaatgcagc
    36781 cccacgacgt ataaccaaat aaatctactc catctttgat agcttccttc atctgctcaa
    36841 tatgctgctt caaatagtca atgcggtaat cgtcttgaac ggttccatct tcttctactt
    36901 tgtctatagc tccgagtccg ttttcagcta tgaacagtgg tttttgatac ctatcatata
    36961 attgattcaa agcaattctc aaacccttag gatcaatctg ccagccccat tcacttgatg
    37021 gaagatacgg atttttaatt cctccagtta ttaagtttcc ttggacccct tcccaatttt
    37081 ctggatgagc actgactgca ctagacatgt agtagctaaa agaaacaaaa tcaacagggt
    37141 aggctgctaa gatttcttca tcacctactt ctatttttaa gttgacacct ttttcttcaa
    37201 acattcgttg cgtatacgct ggataatatc ctcttgcttg aacatcacta aagaacaaag
    37261 aagttctttg ctgctcaatt gttttttgaa tatcatccgg atcacaagaa tacggaacaa
    37321 gaagctgata gctgatcata caaccgactt gtgaaccttt gataatttca tgacaagctt
    37381 ttgtagctaa agcacttgct ataaactgat ggtgtgcacc ttggtatttc gcttgttcca
    37441 aatggggatg gttttcttca attactccta cgctaacaaa agggtgatgt tttacacagt
    37501 tgatctcatt gaaagtcatc caatatttta ctttattttt atagcgtttg aatactgttt
    37561 cagcgaaacg aacgtaaaac tgaataagct ttcgattagg ccatccacca tattctgtaa
    37621 ccaaatataa cggcatttca taatgggaaa gagaaacgac tggctcaatc ccatatttta
    37681 gacattcgtc aaacacttga tcataaaaaa ataatcccgc ttcattgggt gtttcttcat
    37741 caccatgagg aaaaattctt gtccatgcga tagacatccg atagcattta aaacccattt
    37801 cagcaaataa acggatgtct tctttaaagt gatgatagaa atcatttccg tgtcttttag
    37861 gataataata cttgctgttg ggatcctgcg ccgcttttac ttgctgatgc gtcatcatat
    37921 gccattgatc tgtccatttt tctttaggta aatcgctgtc gaatgtatac acatcagaca
    37981 cagataatcc tttttcatct acatcccatg caccttcaca ttgattggcc gctgtcgctc
    38041 cgccccataa aaatccttct ggaaattttt tcatatcgat ccccctaaac ttgctagttt
    38101 tcttgtttga ttatttttct tatgactagt aatgatattt ttgaatctac tactatttgt
    38161 aacaataacc attgtggtcg gatcatatcc ctctttgatt aattcttgca aatctacttc
    38221 catcaataaa tcgcctttac gtactttttt tccatcagat actgcacttt gaaagtattt
    38281 gccatttaaa ttcactgtat caataccgat atggatcagt atctctgctc cttcttcact
    38341 gactacccca attgcatgtt tcgttggaaa aactgttgaa acttccccgt ttacagaact
    38401 gtagattttt ccgtccgttg gaatgatcgc aaacccttct cctaaagatc cactagcaaa
    38461 tgttggatcg tttacttcag ataaatcaat tatttcacct gctgcaggag tacttaacac
    38521 tatatccttt gaggattctt cttcgatttc atccttgtag ccgaaaagaa aagttagcat
    38581 acaggaactg atcatcgcta agaaataact agcaactagc caaacaaatc cttcaccaat
    38641 ataaatcggg aaagacaaaa tacttcttgt agcaactgcc aaagcaccgg ctcctgcggc
    38701 accagctact ccaccaaata tagctccaca tatacaagca atgtaaaatg gtcgtttata
    38761 tttaagagtc acaccataaa cagcaggttc agtgattcca aataatgctg tgataaatgc
    38821 agataaagat aaacttttta ctttcttatt tttcgttttc aaaaataccc caagtactgc
    38881 tcctgcttgc gcagctacgg cagtcataca tgctggacct agcgtatcac gaccgtagaa
    38941 agaaagattg ttggtcatta ctggtacaag tccccaatgt aacccaaaaa tcactaacac
    39001 ttgccaaaat ccgccgataa cagcaccaga taaaacaggg ctaaagttat aaacagctaa
    39061 atatccagct gcaatcagct gacttgcata atctgcaatt ggacctacaa ctaataaaat
    39121 aattgggacc atcacgatga tacaaatgaa tggtgtcaat aaatttcgaa tactttcgtg
    39181 caagcttttg cgaatcttag gctcaatata agaaagaacc catacagcta aaattgctgg
    39241 aataaccgta cttgtatacc ttgctagaat cacgggcatc cctagaaatc gcaaggttat
    39301 gctatcacta tatgcactga caatcgtagg ataaacgaga gctgctgcaa taaccatagc
    39361 gatgaaacga tctgtattga acttttttgc agcagtatat gccaaaaata taggcaagaa
    39421 atagaaaaat gcatcagctg ctgcattcaa aatgatataa gttcctgatt cagtagttaa
    39481 taaattcaaa ctcgtacata aggcgagtac tcctttgatc aaaccacttc ctgccaagac
    39541 gcctaaagtc ggggcaaaaa cagcggcgat catgtctata aaagagttta aaatgccttt
    39601 tttctcagtt cctctctttc cactagatgc atcatcttct agtttcattt gtttggataa
    39661 tacgtcatac acttcattta ctgcatttcc tactacgact tgaaacattc ctccagcttc
    39721 gactacagtg atcacacctt ctagttgctc taccttctcc ttatctgcct tcttattatc
    39781 ttttagggta aagcgtaacc ttgttgcaca atggtaaaca ttgctgacat tttcttcgcc
    39841 tccgacaaat cggacaatat ctttcgctaa ttgtgaatag tccattttta cttccccctt
    39901 gttaattaat gccgtagcaa tccttcttac aagataagta tagttcttag aaaacggttt
    39961 ctccattcaa ttagtacccc ttctaatagc gaacgaaact gtacaatagt gtgtatggtt
    40021 tacttagccg agcaaatcac tcactgcttg aaagaaaaca agtatatcgt ttctcttata
    40081 gtcaaaggag acaaaaaaaa cacgcttgat cttcctttgc tgatgtataa gtggtatctc
    40141 aagctgatac tctgtgattt ttgtttctac ttggcttttg ataagacagc acaacaaagt
    40201 ctcggcattt aacggaagca taactaggtc agaactagga gagattagtt gctgaatgga
    40261 atctatcttt ttatggattt ttatttgatt ttcttctttg tagtaatgat caagcagttt
    40321 tgttttcttt ttttcttcaa ctatggtcag cttttcacgc aaaatctgat aaatctccca
    40381 agattcaaac tcatctagaa cactaggtag ataaatcaaa tcatcccact caaaaataag
    40441 ctcttgctca gtagtcaaaa ttgcatcata ttccgttatt ttgtttgatt gatttttgaa
    40501 aagatacact ggttctatcc ggcattcttt gatccacatg ttcatacttt gttgaatctg
    40561 tttttttagt gtattcaaaa tactaattgg ctggttacta acaatcagta tctccccttg
    40621 ttttcgaaaa ggattcaacg cttcggcaag atacaaaaca aaataagcgc tttcagctaa
    40681 attgggacgt aattgaaaat gtattgggaa gaaacgccga attaaataaa tttctaaagg
    40741 ataacgggag atgatctttt gtacaaaatg attcatggta ttatgtccgg catccatcct
    40801 cgttttcatt tgtttgatat gggttagcaa aaattctgtt tcatggaaca ataacgaaac
    40861 aggaagatct aaaaaacgaa taatcgtttg ctcaaatgct cttagattct tctctatttc
    40921 tttgtttttt tcatcattaa tcatcaaata atttaactct aatagtcgat tttcaattgc
    40981 ttgtttttct tgattggaaa aagaataggg tagttctgat gataactttt ttgtgagggt
    41041 ctctaccatc ggaataaata atgtatacct gtttgttttt tctaaaagtt cttctcttcg
    41101 aagaatggtc aaaacgagat accgagaaaa tcgtatgaag tcctctcctg aaacaatata
    41161 attatatgat ataagaacct cttttaatgt cttttggaca gtcggcatga tattggaaaa
    41221 aattgtactg atttgttgag gaaaccttgc gtgttggatc accgtttctg ttccaacaag
    41281 agataagaaa attctttttg aattttcttc agcaatgatt tttagtcctt ttgtcgacga
    41341 aacttccagt tctaatttag gattgcgctc gatccaacgc aaaatcgttt ttatttgtaa
    41401 tgatacggct gtttttgaaa gaaagaaaat gtctgctatc ttttgcatac tgacataccc
    41461 tttttgaaac aataagtacg tcacaatagt tgaagctcgg aaatccatgc tggaatagat
    41521 tttatgtttc gtcacctctt gtatgatttg ctgtttagtt tcagattcaa ttgattctaa
    41581 aaaataacct gaacgtttat ttgactggat aatgattttc ttctcgtaga tagcaagcat
    41641 atttttgatt tcagtttgga tcgttttctt gttggtacct aaagcttcag ctaattcttc
    41701 gcttgttatc caatgattct tatttcttaa tactacaaga atttggagtt gtcgtttatt
    41761 taagtccatt tgcttacacc tcctctttgt tataaacata caggaaaaac ctctcaaatg
    41821 acaatagtca cttgcagagg tttaaaaatc atttgaagaa agatctatat tcaaggtttt
    41881 taccattaga ctggataatt tgtttataat attcaaaact atcttttttc aatctcctaa
    41941 agcttccgct cccatcattt tgtctatcca cataaataaa gccatatcgc ttcctcattt
    42001 cccctgttcc tgccgatacg atatcgattg gtccccacca taagtaacca atgatttggc
    42061 aaccatcttt tattgcctca gcaatttcct gaagatgtat ttttagatac tcacaacgtt
    42121 ttggatcgtg gattcgattc aattcatctg gtgcttcatc tagtccaatg ccattttcaa
    42181 ctatgaataa tggtaattca taacggtctg tcaattcatt catgacataa cgaaacccta
    42241 gaggatcaat tggccaactc caaggttcgg gagatttttc cttcaaaaag ggattatcga
    42301 aaccatttgc tccgccagta tctacgcgca tttctgcttc ttttttatag acagcgctac
    42361 gataataact aaatgcaata taatctgccg tgttagcttg caagcactgt tcgtctccat
    42421 ctaacattac tggtgcacag tcttcttcct tccatgtcct gtaaatataa gctggataat
    42481 gccctcggca catgacatcg gagaaaaacc atgaattgcg tttaaattgc agtgaaccaa
    42541 atacattctc tggatcacag tcatatgcat aagtcgctaa tgcagaaaag ctacacataa
    42601 tacccatctt agcatttgga tcgattttct ttaataattg agtagcacgg gcgttcgcta
    42661 gaaacatatg atgacaggct tgataaatca ctttttttgt tagtgtagca atgggttcaa
    42721 gtttatctct agcagggaat gtaaccaatc cagcagctgc ataaggcata cgaaaagcat
    42781 tattgatctc attaaaggtc atccaatatt tcactttccc ttggtagcgt tcaaagacgg
    42841 tctgcgcata aaattcaaaa aagtcgatta attttcgatt ttgccacccc ccatactctc
    42901 ctaccaatgc taagggggtt tcataatgac taagagtaat tactggctcg atatcatatc
    42961 gatttaatgt attgattagt ctgtcataaa atacgagacc agcctcattt ggcttctgtt
    43021 cgtctcctct tggaaatatt cgtgcccatg agatgcttgt tcgaaaagct tttaaaccta
    43081 actccttcag taaacgaata tcctcttcaa atcgatgata aaaatcaatc gcttcatgag
    43141 aaagataatg gagtgattcg tctaaagcaa tctcccaaat ctttttttct tcattccact
    43201 gaatactagg atgctggttc atgatcccga taagcgtatc tgtcacatta ggtaatttgc
    43261 cgtcttccaa ccatgcacct tcacattgat tagcagctac tgctccgccc cataaaaaat
    43321 tttctggaaa tatttcctga tccataacta tctctcctcg ctatcaacaa tttcttactt
    43381 gaagtatagc tcgattcatc aaaacaagat attctaacta tttcggcaga agagaagaaa
    43441 aaaattgaat gctactcttc atttttaata tttatatata acaaatacat aagacgatcc
    43501 ccgaaagaaa acactcgtta accatctaag caaacgattt attttacttc caacacaaat
    43561 gcttcataag gtcgtaaatc aactttgccg tctggtaact gtttcagagg ataatttgac
    43621 acaataaccc ttaaagcttc acgtggaata gtgaacgtct gcttttcact ggacatatta
    43681 caaataacga gccattgctg gtcttcatat atgcgagaat aggcaaagac atgctcaggc
    43741 gtcttttcca ctaattcata gtctccccag acgatgatgt catgttttct acgcaaatcg
    43801 atcaatttct tgtacatata aaaaacagaa tcttgatctg ctaacgcttc ttctgcattg
    43861 atttctttat aatttggatt gactcgaagc catggaattc cagtagtaaa cccagcatgt
    43921 tcacgggcgt tccattgcat aggcgtccta gcattgtctc ttcctttcgc cttgattgat
    43981 tccaagattt cctcttttgt aaatccagaa gaaatccttt cgttatacat attgattgtc
    44041 tcaatatctt ttgcttccgc gatatcatcg attgggcaat tcgtcatgcc taactcttct
    44101 ccttgataga tataaggggt gcctttcatc atatggagca agatagcaaa catcttggca
    44161 ctttcttttc gatacacatc gtcatttccc caacgagaaa caattcgcgg aagatcgtga
    44221 ttattccaaa ataaactatt ccatccttca tcacctaaag atgtttgcca tttggataat
    44281 acttttttca gttcagagat actcaagggt ttcaaatccc atttgtcttt gccttcttgc
    44341 tgatctaatc ctatgtgttc gaattggaag accatggata attcatttct tttaggattg
    44401 gaataaagtt tagcgatttc ggtagttgct ccccatgttt cgccaacagt catcagattt
    44461 ttgtcaccaa aagttgcttg attcatttcc tgaagatact catgcagttt aggtccatta
    44521 cttgtgattt ctttatccgg ttctttgcca atcatatcga tcacgtccat acgaaagccc
    44581 ccaatacctt tatcgatcca gaaattcatc atttgataaa tctcttggcg aacctgttta
    44641 tttttccaat tcaaatcagg ttgacgcttg ctatacaagt gcagaaaata ttgccccgtt
    44701 ttttcatcca actgccaagc agaaccactg aatattgagc gcaatctatt aggctctttt
    44761 ccattgaccg gatcacgcca aatataatag tcccgataag gattttcttt atttttacgg
    44821 gcctcaatga accacggatg ttcatcagaa gtatgattca ccaccagatc catgatgata
    44881 cggatatttc ttttctttgc ttcttcaatc agttcttcca tttcttccat cgtaccgaat
    44941 tctgccatga ttgcttgata attactgata tcatacccat tgtcatcatt cggagactcg
    45001 tatactggag aaagccaaat tgcatcaata cctaaatacg ccagataatc caacctggaa
    45061 ataatccccc gcaaatctcc aataccatct tgatttgaat cttgaaaact tcttggatag
    45121 atttgataaa caactgaatg gtgccaccat ttttgttcca tgattttcct cctataaatg
    45181 gatgtttcta ttttttgctt aatcatttat tttagtctct ctcactaaaa attgtaacgc
    45241 tttcaaatag ctattgcacc ttgttatcgg taacagaata aaacaaaaaa acagctgagg
    45301 aaattccctc aactgttttt tgaaaggatt gatttatgca gggaagaatg ctgatttcac
    45361 aacttcttta taaacggtgt tcactcagct gtcccttggt attagctcaa aaaacggcaa
    45421 aatataagaa actatttttt cgtttttttc tctaatactc aggccagaac gctgatttca
    45481 caacctcttt atttcacatt caatatccac atgaatccca caaatacaaa gaacagacca
    45541 tacatgattg gagatacttc ttttcctctt ttagctgcta acatggtaat tggatagaag
    45601 ataaaaccta atgcaatccc atctgaaata ctataagtca aaggcatgcc gatcaagatc
    45661 aagaatgaag ggatcgcaat ctctaagttt ccccattcga tttgtcgcaa agattgtgcc
    45721 atcaatactc ctaccataat caatgctggt gcagttactt gtgaagtaac aactgatagt
    45781 aatggagaaa agaacaagcc taacaagaag aaaatccctg tagtaatagc tgtgatacct
    45841 gaacgtcctc caacggcgat accagctgat gattctacaa atgcaccaac aggagaagta
    45901 ccaaataagg aacccgcaag catagctgtt gaatcagaag ctaaagcttt ccctacacga
    45961 ggcatcttgt tgtctttcat gaaacctgct tggtttgcta atccaactaa agttcctgct
    46021 gtatcaaaga aagtcacaag caagaatgtc agcactacga cccacatttg aagagaattg
    46081 atgtccccta catgttttaa tgcaactaaa aatgttggtt tcaaacttgg tgctgcggca
    46141 acaatttcag aaggcattgg aatcaaacct gtgaccagac ctaaaatcgt tgtagctgcc
    46201 atcccgatga agatgccacc tggtacacgc cgaacaagca agatagcagt tacgactaat
    46261 ccaaaaatcg tcaaccaagt agaaccaacg ttgagtgatc ctaatcctac taatgtagat
    46321 tcattcgaaa cgatgatccc accttcgctc agaccaagga aagcgataaa tagaccgata
    46381 ccgccagaaa tcgcatattt caaatctgct gggatcgcat caatgatcat ttcccgcagc
    46441 ttgaagattg tgatcaaaat aaaaatcaaa gaagcaacga atacgccggc taatgctgtt
    46501 tcccatggaa tccccattcc taaacaaaca gaataagcaa aaaaagcatt gatcccaaga
    46561 gcaggtgccg ttccaattgg ataacgggct aataccccca ttaaaacaca gccgatcgca
    46621 ctggctaatg cagtcgcagt aaacactgct ccttcatcca ttccagaagc acctaataca
    46681 gttggattta caaataagat ataagccatt gagataaatg ttgtaaatcc tgccagtacc
    46741 tcacgtttta ccgtggtgtt caatttttct atttcgaagt aggaaagtat tttttccttc
    46801 atcttccatc cccctaaatc cgaacattat aaataaagtc cgttaaaatt tcgatttatt
    46861 aataaaacaa cgtgttttat catatactaa aacaaaacat aagtaaacaa aaaattcgga
    46921 ttttaagcaa aatccgaacg ttccatctga ttaaatccct ttatctcaaa gttcatgaac
    46981 attcactttg gattacaaga atttctttat tgtgttaata aagtttcttc attctagtct
    47041 caaaaatcaa tagtgtgatt tgattttacc atttcgtttc tgttcttctt tgatgaattc
    47101 ttttgtatcg acaggattca gattatttag tccgccaaaa cctgtatcga ccatttttcc
    47161 ccagcctttt gtcttctttt ttcctgattt gagattcttt gctcgaagct tctcactatg
    47221 ttttgctcgc cgatacttca aataaccttc taatcttccc attagatcca ctgtttttcc
    47281 tcctttttat tcaatcagac gactcagctt ttcctataac aaaataattg ccttcagggt
    47341 cagaaaaatt gaaagtcaag atgccattgt tatctgtgat ttctcctggt tcttccatgt
    47401 tctcgtagat agtttcaaat tcatccgtaa aaaatactaa agaaggcggt ggtcctaata
    47461 cctctggtga aaacttctgc acaaatactt ttgggaatac gcctaattct aattcttttg
    47521 agatgctgag tacaatactc ttaaattctt ctggcaattc gattgtttca gaaatttctg
    47581 caccaatttt ttctacaaag aatcggcaaa tcatctctac gtcattgaca taaagcatca
    47641 cacgtgtttt ttgtatcatc atttgaccct tctttctatt tgattttctt tcctgtctat
    47701 aaactgattc cattatatca cgaaagcgca aacaccttgt gtttgatact attcaagaaa
    47761 aataaagcaa tagtttctag gattgctttc ctccacaaac tttttttaca aaaaaaaaac
    47821 ggcaatgaat gccgctcttc ttatttcgat tcttttataa ttctgcttct gattcatctt
    47881 tggttagtgt gtgtctaaca ctagttacgc caaatgtttg atcgattttt tccttcaacg
    47941 cttcgattgc ctgtgcgcca cgtgccgctt gttcagcatt gatggattca atgaccagca
    48001 ccgctgcttg tgtttcttcc gtcagcatcg ttctttgggc ttcacgccag ttgagacagc
    48061 gacagatcgc tccttgttca tcatagtaga tgatttcttc cggaagtgcc ggagcatcgg
    48121 aatctgcacc taaaggcagg aatgattcgc caccttgggc ttttcctaaa tgcagatttc
    48181 ctgcgatctt ttcgatatct tctccgccgc aaggtacgcc aaaagacaag gaaatactat
    48241 tatagatatc tacaagcgga ttgattggga aaaattcccg ttcttgattt gcacgtttca
    48301 gtaaagcttc aatagaagaa cgtgcacctt ttttagtctt gaatgtggta aatgcctgac
    48361 gccactgagc aatgacttcg ttttggctga atgtttcttc tgtaaggtaa tttcttgctt
    48421 cttttgctgc ctcattcaat aattgatgat acgtttcttc actttctttt gttacgtggt
    48481 tatcgatacc atttacggat aagatttcga tggttgcttc aggaaatact tcccagaaat
    48541 tggtatccac tattactttt ttcatctgtt cacacctctt gattagaata attgcttgat
    48601 gaatagatag tctgtttggg gatcatctcc catataaaaa acatgttcgc tgtatttgat
    48661 aaatcctttt ttacgataaa aagcgagcgc aacatcgttg tgttcccaaa caccgagcca
    48721 aatggctgtt ttttgctttt cttttgcttt ttcaatagct gtatctagta aaaatgtacc
    48781 gataccttga tgtttaaatt tttttcgtac atagattcgc tcgatttcta aaaaatgatc
    48841 agccatttcc tcagattgac tcgttcctgt atttagtttc aggtaacccg caggctcttg
    48901 atcgatactc actaggaaaa aatcggtttc tttatctttt agctcttctg taagtttttc
    48961 tagtgcataa gcttgtgtca agtaatcagc taaatgctcc ggtgaattat cttttccaaa
    49021 tgtatctgta aatgtttcga tactaatttg ttgtagtaag tctacatctg aaggcgtcat
    49081 ttttcgaatt tcgtatttat tcacggcttc ttcctttcaa tagatccttt tattgccttt
    49141 tttgacaaaa ttccaatctt cgctaacatt cttgcatact ttatttaaaa gatattccaa
    49201 ttgttttgct tcttcgtcag aaagaccatt taatgcgact gcattggagt agttgttttc
    49261 tcgaatgatg aaaggataga tttctgctcc ttttttagtc ggatagagtt tcttgatttt
    49321 tttattttct ttatcttcca aacgttcgat catcccattg gattctaatt tcttgattgc
    49381 tcgggcagtc gttgtacgat ctactttgat catttctgct agtttttctt ggatgattcc
    49441 aggattttcg caaatacgta ctaaataaag atactgtcct cttgttaaat cgacttcttt
    49501 gaattcgata ttgctaatag aatctagcgc tcgggcaatc attccgatgt ctcgaaggat
    49561 ttcagccatt tcatcccacc tttattttgt ttgtaagact agttcacctc tttttgttgc
    49621 aaatgcaact attttcaata aaaaaatcaa gttctttttt aataactagt aaagtatatt
    49681 cttttcttct tttacgaaaa agctcaatca caatagatct ggtttttgtt ttctaaaata
    49741 agtaactgtt tcttcgttgt tcgcttttct gatagctttg gcaactcttc tatactaaaa
    49801 aatcccatgt tggaagtttc attattctca ataaacttgg cctcttcacc gtggatcgca
    49861 caagcaaaaa caagtttata atactgaaaa agctgtggaa tatctttttg tttattcgta
    49921 tcaaaaactg ctcgcaactg agtagtttct actgttaatc ctgtttcttc atagacttct
    49981 ttacgcacat tttcttcagg agacaatcct atttcagcaa atccaccagg aagtgaccat
    50041 tctttcgtcc gtttatcttc gattagtagg accttgccat cttttttgat ataggcacga
    50101 acatctactt ttggtgttgg atgtccttct ccaatcgttg tgagcgcttt tatttcttcg
    50161 aaagtttctt ttcctatttc actgatcagt tccaatgaaa tcgtccggat ctcctcaaaa
    50221 cgctctttat caaatacatc ttttccataa tatagaccag cttgagaaag tgcgagtagt
    50281 cttttgtatt gagccaactt cttgttcatt ctcttccctt cttttttagc aaatgtatga
    50341 ctatgtaatc aagtatagaa gactggttta attacggcaa ataaatataa tgaaatctgc
    50401 aataaataaa agaatgttaa aaaactcgag aacaaaagac attcgacttc tctggggctg
    50461 tgaataaatg gcgttcaaaa gcttgcatct gcggtaataa gccccaccaa acgaaaaata
    50521 tgacgagcta ttcttgtctg gctgttctta ttaattgagg caggacagct ttttcacaac
    50581 ctccccacta aacggtgttc tcctaccaac tcctcggtca caagtcacaa tattcatcaa
    50641 acatgagaag ctgttttttt gaaattgctc cttgtgactc ggagctgaac gacaggctca
    50701 cgacctctcg gtaaacagcg ttcaaaagcc aatttttcga tattaagcca tttctttgtt
    50761 acttattgtc attgatttct ttttctaatt tatccaatag tggagtgtaa tccacttgag
    50821 tatagtctgt tacatcaaat tcatatagtg ttcctaactg gaatttgtca tattttcggt
    50881 cggcgatgat ctttttgaat gcttctttcg taatatgatt ggtccctttc gttcgatctt
    50941 ccaatacgtc accatagtga taatgatcca tgatatagct caaatgacga tctgattcac
    51001 gatcacgttt gtaccgacgt tgccataaca cttcaaagtc tgctgttagg cgaatcgtga
    51061 tcacctgata tccgtatcta tctgctaatt cttggagtcg tgctttttgc ttatcactaa
    51121 aaggatactc ggacacaatc actttctttc ctgcttccat atacaaatca agtgctttgt
    51181 aatagaaagg ataaactttc gtcctttctt gttccgcccg ttcttccaaa ttgttaaacc
    51241 cgatggattc tgcatagtat tccttgattt catcgagcgt gatggcatac atatctggaa
    51301 atcgttcccg tagtttattc ataagatatg tttttcctgt accaggacta ccagccagaa
    51361 gaatgaaata ctttttcatc tcatttattt cctaagttaa ttggactttc caagttcata
    51421 aacagtccaa tcttatgctt gacaatttct tttactgctt catttgctgg aatcacatta
    51481 tggcgaagag acttgttgat ttctgtttca ctaaaggttt ctttagctac tttcgtccag
    51541 ttgactaaaa gctccgttcc aacattgaat ttgcggatcc cgttattgat caattcagga
    51601 taatcttctt ctttcacacc tgttcctcca tggataacta gggggacatc aactactgca
    51661 tcgatttctt tcagcaaggg aatgtttact tctgtttttg atttgaattg tccatgattc
    51721 gtaccgatag caatagctaa tgcatccacg cctgtagctt ctacaaattt cactgcgtct
    51781 tccggtcttg tatatacctt gtcattttca gcgacatgga ttccttcttc tgtaccgccg
    51841 attgttccaa gttctccttc tacggaaaca ccgtgcgcat gggcatattc tactactgct
    51901 tttgtcttca ggatattttc tttgaaaggc agatgggacc catcatacat gacagaagta
    51961 tatccgctgt cgattgcttc tttgatatca tcaaagtctc gggcgtggtc taagtgcaag
    52021 actgcatcaa ccatttcttc ttctgcaata gctgtcatta cattgactaa cacatgcatg
    52081 ccgatatatt tagcggtatc gacacttgtt tgaataatga tcggcgaacc catttctttt
    52141 gctgcgccta gcatagcagg aagcatttct aggttatgcg tattaaaagc tccaactgta
    52201 aaattcaact cttctgctgt ttttgttact tctttcaatg ttgtatacat cttttattgc
    52261 caccttatct ttttatttgt ttcctttgat cgttacttgt tttgcaattt gtcgcatctc
    52321 atccattttg cccatgtagt aatcgatccc ttgatcatca ccagcacgag cagcatctgc
    52381 acgcttctgg ttatagaggc tcatcagttt tttataccca tctccgatcg tctgtttatt
    52441 ttccaaactc ttttctaaat attggatggc ttgatcgttc acatacaatt cagaaaattt
    52501 aagtccaact tgttcataaa gtttcgctaa tttatgctta tcttgggtag tggaaatctc
    52561 ttgtttcaat tgtgtaatct ctgattgaat cttttcggtc gcttctggcg atagggcttt
    52621 ttcttctttt gccagaactt ttttcggttc tttttctttt ttcttaaaaa atccaaacat
    52681 cattttccct actttcaatt aaaatgcttt caaaactggg cttaagatcc aggcatataa
    52741 gagtgctgcg gctactgtat ctacatcggt tgctgtagca ttgttgaatc ccatcgaatt
    52801 aaagatcgtt actagcaaag cgggcaataa tgtaataaag aaaccatgag caataccgcc
    52861 aatgatcgct cctcggcgtc cgccaactgc gttgccaaat atccctgctg tccctccggc
    52921 aaagaaattg gttagcatac caggtaaaat catcgctaag ccgaacatgg gcaaagtaaa
    52981 catggcaata atcgtaccaa tcgttgtcgt aatgaaacct aaaatgacag catttgggct
    53041 ataaggaaag aaaactggac aatctaaggc agggatcgca tcaggaacta atttcatagc
    53101 tatccctcga aatgccggca cgatttcacc taacagtaga cgtacaccag ctagcaatac
    53161 atacacaccc actacgaatt ggatggcttg taaaaaggca aacatgatat agttttgatc
    53221 tcctgataat tcagaagcga atggttcgcc tgcaaataaa acagtgatga tatatagcgg
    53281 gaccatcacg accatgacag acaaataagt atcttgcaga aattcgaaat gtgtcggcaa
    53341 cttgatatct tcgatcgact ttttattttc gcctttctca ccaaaaagct tagcaacacc
    53401 ggcttcaaat aagtacccga tcgtacaaaa atgacctaaa gcaatatcat ttgatccagt
    53461 gattttacga atgatcggtt gcgctactgc cggcatagca atggcgaaac aagctccgat
    53521 aaaaccaccg accaagatca atacgatccc tcgcagaccg gcaaaatagc caaagactgt
    53581 cgtcatcgtt gccatccata aaattgcttg accagttaaa aaaatgtact tccattttgt
    53641 gaaacgagcc aaaataatat tgaatacaaa aatggctaag aacgtcagtg caatatctct
    53701 acctaaaccc aaatcattca ttgcttgacc attgatagat tcaatagaag ggatgatccc
    53761 ttgcatatga aatccttcag taaagatttt cccgaaataa gttaaacttc caacgatgat
    53821 gctcgaaccg gcactcaaca cttgaaatcc taggagtgtc tttaacgtgc cagagatgac
    53881 ttgtcctgct gatttcttct gcagtagtag acccaacata gcaatcaatg caatggtgat
    53941 cgatgcctga gtcaaaatat tttcgatgat aaaattgata acgcccatgt ttttaccctc
    54001 ttttcttttt gtatttagat aactccctta tcttgcagaa ctggggtgat tttttcttca
    54061 atttcatttt ttgaaacaat atttttcaaa tagatcatcg ccgttttagg atcaactgcg
    54121 aacttttcga actgcgaacg aaaattttct gctgtgatga tcacatctgg tttcatggaa
    54181 actgcggaag aaatatcaca atggtccagt ttggcttcta ctcctaattt gttcaaaaca
    54241 tcctcagcag acatctgtgc tgcaaaacta cttcctaaac ctgcaccgca tacgaataaa
    54301 atgttcaatt tgttcatctt tgttctcccc cgtatcattt attatttctc aactactgaa
    54361 aaaagcagtt gtttgaaatc ttcgatattt gtgcattcaa tcaatcgatc caacttctct
    54421 tcgttgttga tcaattcaat tagttctttc atgatgttca gatgcgagta ggagtctact
    54481 gctgccaaac aaaaaataat ctttactgga tccatttcag gattaccgaa atcgattggt
    54541 tgctcaatcg tagctacgct gactcctaat ttattgaccc catcttctgg tcgggcatgg
    54601 gctagtgcca tgtgtttgcc aatcacgata tacggtccgt aatcattcac tgcacgaatc
    54661 atcgcttcga catagcgctc ttcgacaatg ttttctttaa ccaatggtct agcagctagt
    54721 tcaatcgatt cctcccaagt agtggctttt tctttgatca tgatattgct gtccgtcaaa
    54781 atatctttta acataggctg gatctccctt ttgttgattt ctaaattgtt tgtttcgaat
    54841 aatttttcta acttgccata gatgattcga tctactcggc caccactttc tttcatgaca
    54901 tctattattt gagtgaataa ctccgtcgat tcatgactgt taggctctaa ccgctgtagt
    54961 tcttcatttc ttttcaaaaa gtcttctata accaagatat tcgtctcagt taaaatcgga
    55021 tcgacaacta aaagcggctt atttcgataa ttcaattgaa aggtgctgaa aaccagattg
    55081 acatccaatt tatctactaa ttcgatttct tttgaactta aaactgcagt aatctcgatc
    55141 tgaggaaact tttctttcag attctctgct aacagatttc cagtagccat cccatggtta
    55201 cagacaacga ctgatttata aacataattc aagtctcgct tgattacact ggcgatcgtc
    55261 gaaaagtgga tgacaagaaa agctatctcg tcctccagta tcttgccacc aattacttct
    55321 tcgatcgtag gaacaaaatg agtgactgcg cggtagattg ggaaataatt tgttcggatg
    55381 ttttctttca atggattcat gacttggata tgattcttga ttcttacaat cagtgcagcc
    55441 atgtgcttat agagattttc gaataaagct tcttccttta gatggaaagg tacgtgtgtc
    55501 tcgttctcta caaattggat caattggatc gttagtaatt gagcttgtac ccactcgatt
    55561 gaattggaga tatctctagc attgaacgtc tcaatagtga aacgaagata atttctttct
    55621 acttgcggga cattgtccaa ttgaaattcc tcgatcatgt ggtcaataaa tgcagaaaag
    55681 ctactgtctt ttatttctgt atttttccaa ttaatggcag agataaattc atgtttcctg
    55741 attcgctgga tccagatcaa tgtaaaaagc aggatttgtt ttttataaat atcatcttct
    55801 tgtttcaaca acttattgga atagatctcc tgtatttttt tgatttccac caaaggaaaa
    55861 taatggagaa agattttttg agccggtgtt aattgtgcat cttgattcat aaagaagtcg
    55921 gtcattccca gattctgatt gataaaatca tagatcatcg tacggataga tcgttctgaa
    55981 cctttataaa ccagtccttg ctttccataa ctgacgatct ctatcccata actgaccagt
    56041 gttgctcgta accgtctcat atcttcatct aatgtacttt tagagatttg aaattcttct
    56101 tcttttttgt ttagatggat cgggattcgg ctgtaagcaa cggctaaaac tagatcaaaa
    56161 atacgttcgc gccgattcaa aaagccgtct ttcacatctt ttatttcagt ttctaatcga
    56221 gcttgctttt ccttttccag cttcaacaaa aaacctttgt tgcgaattgt acggatctcc
    56281 ggaagctttt tactgctcaa ccagatattc gcttcaagaa cttcctgacg gatcgtccgc
    56341 tgactgacat tgaactcact tgctagatgt tttgctttta ctggatattg ggctgtcatg
    56401 attctgtgaa gtatttcaat tgttcttgtt ttcatagaaa tgatctcctt ctgatttcaa
    56461 gtatatggtt ccgcttacat aataaaaagt agatatttct gccacttgaa gtggaaagaa
    56521 agtaagcaaa gcaaacaaaa aataagccat atgctttttc atctcctcaa cgaaaaagac
    56581 atacgcctat tattacaaaa attttgccca tctatacaaa aaagaggttg tgaaaaagct
    56641 gtcctgcatc aagtaataag aacaactaaa ctaaaatagt gcttcctatt tttcgtttgg
    56701 ttgttcttat tatcgcagat gcaagctttt aaacaccatt tagtggagag gttgtgacag
    56761 agatgttcag ccttgagcga taagaagcga ttttgaaaaa tcgcttccca tattttacaa
    56821 aatcgtgcct tattgccgat aggctatctc tggcacaccg tttattcaga aaaaggagct
    56881 gcgacaaggc ttttgtcaca actccgttca taaatatttc ctgtcaatcc agcataatcg
    56941 gctgaataaa atcggcttgc catctttttt ctttctcaga aaaatcaaaa taccatatct
    57001 gagaaaaata ctgtcgttgt gtcttacttc ctgagatcaa tcgcccatct tttcgatcga
    57061 ctgaataatc acagcatctg aaatcaattc ggatggcaaa actattttcg tggatctgtc
    57121 gataatttcc tacttcctga atagttattt ttttagtatg atttcttaca ccgtctgctt
    57181 tgtttttttg cagaactttc tgatgttcgg caaacagctt gtctgtataa cagcttctgg
    57241 ctttttcagg agtttcttct tcccaagcgg attggatctt catgaatatc ttttggattt
    57301 ccagaaactg tgctttcttt tctttagccg ttcctgacat gcgggacaat atctccgctt
    57361 tcagcctttt cttttgtctt ttattcttga cgatagaaaa agcagaaacc cctcctactg
    57421 acaaaacagc taatgcaaga aatcccgttt gctcataact agaaggacct gtacctggac
    57481 cataataccc ataagaatct ctgccgtaag aacgactgcc aaaataactg cccccatatg
    57541 aacgaccacc aaatgaacct ctgcccgaac ttcgaccgct agatgtacct ccaccatgac
    57601 cacccgcgac agcgaatcct tgggtcggca gagcaaacaa acataggccc actaacaaaa
    57661 tgattgctaa ataattgatt tttttcattg tcttcctcgt tatcttttat tacaaaaaac
    57721 tatttttatg atagccttgc taaaaggaag agtcaataac cagatgcata aactgttttt
    57781 ttagcaattt tgtcttattt agtcattgag taacatcgga caaatgtatg tgtcggcagt
    57841 ccataattcc tctatcttca gcatgaacaa gcttgcagac aagagatctg cgcttcctcc
    57901 aggagagatt tggttttcct gacaaaagtg caacagtgct gtaaatggac gatttggtaa
    57961 agcactttga ctagcagcat gagcaagttt ttgcatttcc actaacgttt tctgatcact
    58021 gcgatgcaat acgcatgtgt catctagcga actcatcaaa actaacaaca tatgcatttg
    58081 tttctgtaca tatgaatcat tatctagctc cttagctgct tgaattgcaa gcctgatatg
    58141 cggataccct aatatcgctt cttcatatgc accatttacg ccatattttt gcttcaccct
    58201 atgaccatga gtggtttttt tatgacgata ttttgtatca ggaaaagcag caagcttgct
    58261 gacatcatca agtattttcg ataaagaaaa aggctgttcc atactgattt tttgtgcaat
    58321 gacactgatc aatagcccca ttgcccaaat cgctccttta tgggtattga tgccatttgt
    58381 agcaatcagc attgcctttt ccgcttttcg cccaatctca gcaattcttt ctcttaactc
    58441 ctgatcaata gcatgatgcc atgctatttg agccatttct tcaaaaaaag gagttagcgt
    58501 cttagcagac ttaagaaata aagcatagtc catatcggaa tgtgcacccg catccagtgc
    58561 atccactaat ccaggttttg gacttaatgt tacttctgcg atcaatgctt cctctaccaa
    58621 cgcagcgagt tgctgagtca ctgctttttt tcgttcgtca tttatcatga cactcactcc
    58681 ttcttcctac tattacttgc tgaaaccttt tttgatagct acccaaatga tatgaagtaa
    58741 ccagcttaaa gcaaatgcac aacttgccgt cattagataa gctacaagaa tcatgactcc
    58801 tgaaggtaac tgcagccaac tatctttaaa caataataac agtacttgga aaacaaatac
    58861 attggctaaa tacgtacgat aagcataaac agacaaccat ttgaacaatg gcaattttgg
    58921 cgaatcgttt acaatcattt tggaagcgcc tatgaagaca gcaaagatga tgactaaact
    58981 gtataaactt tggatcgtat tcaagtaagg tgcattcgca aagctcaagt ctcctggatg
    59041 tgcgagcaat gaacggacag aaaagaacgc gataactaag gcaacaggta agaaaagata
    59101 acgtactctg tccaaatatt gatagacttt ttcgtgataa acaaatgcgg ctaccccata
    59161 aatcatgaaa ctagcaacaa accgatctaa taagtaccag ctgtcatgat aaggcccagt
    59221 caatacttgt gtttgataga acagatacca tgcgacatat aaaatcgttg aaccaatcaa
    59281 tactggccat acatattttt tattagcaaa tactttgtaa ccgagccaaa caaaaaacgg
    59341 catgaacaat tggatctgca gcatcataac ggtataccat aaatgaggcg ctccatcacc
    59401 tgtgacatat ttcagtaaaa agcttgcagt atccgtatac ggagtttgtt gttggactgc
    59461 tggaaatagc caaagataag ccgtcgtcca tagaagatac ggaacgacta gttcaaaaaa
    59521 cttttctttc aaaaattccc aataagacaa atgctgactt gtttttacca tattataaac
    59581 aattgcaaaa ataaacattg gtgctgtgta tttaacgatg acgtaaaagg taccaagaaa
    59641 agctgtattt gttgcgctgt ggctgtttgc caaagcaaag ctcaatatcg tttgcatcat
    59701 aacagccgtt acagctgata ctttctggaa gtcacttacg ttgattttga tttttttgtt
    59761 ttcaaacatc tctttctctc tctttttctt tattaccaaa gttctttggt taatttaggt
    59821 ccttcgactg ttttcaatag aatttttttc tctggctctc tcaaatactc ttttagtgaa
    59881 aaaccgcctt gccgagtcac tacttgggta tcgaattgct caaaaaaagc aggatgcgat
    59941 tgaattacct gaattggcaa ttcaatcggt gaatttgcgt acagcagcaa atcaaaatca
    60001 ctggtttctt ttactgccgg aatcccagtc gataattcaa atcctaagct gccgccgatt
    60061 ccccatttac atcctgataa tatgtttcta gcagcatgaa attgctgata aacaggataa
    60121 tccatgattt tctcttgtct atacgattct tgttcgatga tgtcccacgg atgaatgact
    60181 tgtttgacgg catgttttga gatttctgtt gaccatctct gattgcgggc aggtccacgt
    60241 aaaccaatcg gtagtatttc tgcgtgatcc gtcgacgcac gacgaactgt tccgaacatc
    60301 ttttcagtta gaacgaccca ttcaggcaag gtgaaccctt ctatttcatg tttatcaaaa
    60361 aggacaatat catgtgcttg aatcattttt tatgcatccc attcttcgtc cattttggca
    60421 cggactttat ttgtttcgac acgtccgaat gttttggctg tttcgtttgt gtatcgattt
    60481 gtcagcatcg tgtcatttgt attgcggaca tcttgaatgg cttcattgat tgcttcgatg
    60541 actttgctga cattttgttc tgaagcagct tggtcggtga tatcttctag gaaatgatag
    60601 atcgctccta gttttgtata attattgata tcgtaagcga tagctggaac tttttcagca
    60661 gctgcttcga tttcagcaac cgaacgtttt gtcacacgtg cagcactttc tttagacatc
    60721 gcttggacgg taatttcttt attgtttaaa gcaatcaagc ggcttgattg taatccatgt
    60781 gctaaaaatg cacctgaaat agcatttcct gcaatcaatc caataactgg atgtccagct
    60841 tgacggagtt ttgcataagc agcagcacta ttagccaaag ccacatggat accgatcaat
    60901 tcttcgttat agccgtatgc ttggcttggt acatcgatca caacgatgat tggccgtttc
    60961 acttttttgt ctttatcttc ttcgtaaacg tgatccaaaa tttgtcccat gcggaaacct
    61021 tcaactaaac caacttcacc gtttcgtaca cggtacatcg ggtttttagg atcaggtacg
    61081 attgatgtca cgatggcttc ttctatgaat ttacttgatt taccataata cacagtacta
    61141 atagaagaag ttggattttt catgccagtt agtgccgcaa accaatcgta accaacactt
    61201 gctgcagctg gttcatttcc ttctgctact tctggtaagt caattgattt tgcttgatgg
    61261 ttagcaattg cttcattgta atcgtcaatg gccattggtt ttgaaagatc taaagaatca
    61321 agtaatgata aataaaatgc tgagctttca ctgcgatgcg tgtcttttcg ttcgtccatt
    61381 gctgcgatga cagcagcttt gattgcttct acactatcag tcactaattc atcaatgatt
    61441 tttgattcta cccgttgacg agatcctaat gtattccaaa tcaagtcttt gtcactagaa
    61501 tcaaattctc gaacgcctgc ttcttgttca ataacttctg gtccattcaa accgactctc
    61561 gctttttttg ttgcgattaa ataactcatt aatgctgaag taatcgacat accgccaaat
    61621 gatcctacac gtcctggaat caaaccgatg actggtacat attgttttag agcaatgatt
    61681 acatttccga tttctgaaat agataacagt ccgtagtttg cttcttgcaa acgaacacca
    61741 cctgtatcta gtacaatgac tggaaagatc tcatttcctt ttttattttc ttctaacaca
    61801 tgttcaagtg cagcaacgat ttttgcaccg gaaacttcac cgataccgcc accttggaat
    61861 tttccttcca tagcgattac tactgcttgt ttgccattga tcgtgccacg gctgacaacg
    61921 atcccgtcat cactttcagg gacgattcct tgtgctggta aacttggcgc gatgatttga
    61981 tcgaatggat caatcaattc acgtccattg tcaagtagag cgttcactcg ttctctggcg
    62041 tttaattcta caaaactatt tttcatctga aagttcctcc attgcttgcg tcaatcgtag
    62101 gtacacaact cctggtgtag caccgaagtc attgatcacg atatctgctg aaattggata
    62161 acgatcaaaa aatctcgtta atacattgtt ccatacttcg ccgaagccat cgcttcctgt
    62221 acaaattttt acagtagatt ctgttttttc tgttggaaac atcaagattt ccaaatctcc
    62281 tgaaccgacc actcctacat ggattttctt attgatcggc tgtttcgttg gatatttata
    62341 agctaattgt tccatggatc tctccccttt ttgtaaaaca gagcatacac gttctgctta
    62401 ttcgtctttc ttcttccatc tgggtaaatg gcgacaaaag gtttttctcg ccaattttat
    62461 gaccaagttc tgaatttcat tggtggttca tacaggccat ctgaccattc gatcaaatca
    62521 tcgatggttt gtgcagctaa taatgaacgt ttcgcttcac tacgtttgat gcctagatct
    62581 tctggtaatt tcacgatgcc ggctgcacgc aagctatcta gtgattcttt cgtgctagtc
    62641 attccaagag gtgtaacacc gccaattgct gcaattgctg cttgtcgttc ttcttttgtt
    62701 tttgctttgt acaaataagc aattccttct tctgtcacga tatgtgtagt atcttcgcta
    62761 taaatcatca ctggtgcatt ggctaagcct gcttgttttt gaacagctag tgcatctaat
    62821 tcttcgacaa agactggttt tttatttgaa ccatatgttt caaccatttg aacaactaat
    62881 ttttggcctt tccctaatgg atcatcattg tcgcgaagtg attgccatgc tggtgtagaa
    62941 tgacgacgac cgccaggatt atgtcccatg ttaggcgcac cgccaaaacc agataaacgt
    63001 ccttttgtta cggtagaaga gtttccttcg taatctaatt gcaaggttga accgataaac
    63061 atatcgatgg catattgtcc tgcagcttgt gataatgttc ggttactgcg catcgtgccg
    63121 tctttaccga caaaaaagac atctgggcga gcagcaatat atttttccat accaacttcg
    63181 ccaccaaaac tatggatgct ttcaacccaa cctgattcga tggctggaat catcgttgga
    63241 tgtgggttca atacccagtt cttcgcgatt ttccctttta accctagtga ttcaccataa
    63301 gttggcagta acaattcgat agctgctgta ttgaatccaa taccgtgatt caaagattgt
    63361 acgccgtgtt ctgcgtagat tcctttgatt gccatcattg ccattagaat ttgcaattct
    63421 gtgatgtttt gaggatctcg tgtgaataaa gcttctaatt gataaggttt atctgctttc
    63481 acgacaacgt ctacccagtc accagggata tctacacgtg gtaaagaatc gacaacttcg
    63541 ttaacttgaa cgatcacgat accatctttg aaagctgcag cttcgatgat tgttggtgtt
    63601 tcttccgtat tgaaacctgt gtacaagttg ccgtctttat ctgctttatc tgcagctact
    63661 aaaacaacat ttggaatcaa atcgatgaat aagcgtccat aaagttccaa ataagtatgg
    63721 atatcaccta atttcattgt gccgtcttca atcatttggg cgacacgcaa gctttgtgca
    63781 ccagcataag agaaatcgat cttgcttgcg attccttttt caaaaatatt caaatgttct
    63841 ggtcgtgaga tactagacat gatcaaatgc agatcattca ctttttctgc atctactttt
    63901 tcaagacttt ctgaaagaaa acttgcttgt ttttgattgt cgccttctaa tacaactttg
    63961 tcgccgggag caatcagttt ttccattact tctacgattt tttcagtttc tacatacttg
    64021 ccattgagca agttgctgat tttttccaat cgctgcgctt ttttttcgcg tttagaagcc
    64081 cagttgcggt ttggtttttc cataattagt catctccatt tttgatatag aaacgtggcg
    64141 tcatcaatac catgttggtc tagattgatc gtacggatcc ctttatctac accaaatttt
    64201 gtatgaatca gctttgtcaa agtattgccg gggggaaatt caatcgtcag atccattcct
    64261 aattcttttg ccaagtccat catttggttc cactgcacag ggaaagctag gttttccaac
    64321 aaatctttac gaatctcttc tgcgtcctga gtggctcttc catccgtatt ttttatatac
    64381 aaacatctag catcagatag atggacagac tgcatatacg gcttgaattt cttgaccgta
    64441 tcattcatca agagacagtg agatggcaca gggactttca gcagcttcgc tgtttgcgct
    64501 tggtgccgtt tggcttctgc caacgtaacg gataaacctt cgatactccc agataacgta
    64561 tgttgcatcg gacaattttc atttgacaga taaactggat ggtcaggatc aaatgttttt
    64621 gctacaattt cctcagcttc gcttctcgtc acacctacta ctacgcccat tgcataaccg
    64681 cttggataag cttctttcat taagactgcg cggtgataga ctagttccgc tgcattctca
    64741 aatctcaaag atcgacaagc aacagctgca caaaaagcac caatcgaatg tcctgctgca
    64801 atatcaggct gaataccgtt tttttccatt tcatctaaat aaaatactgc ttttgtcagt
    64861 aatgctagct ggataaaaac cgtatcttga tagttttctt ctttatcaac taaccgatac
    64921 cccgtcacat tttctaaacg ttccatgtac atttcaggga tatccgctaa catccctaac
    64981 ttctgactgc cttgtccagg aaataagaaa cctgtactca tgagcctcgc ctcctcagca
    65041 cttacttttt ccactgctat cttagtcaat ttctgctata ataaaaaatg ccaaaaaaag
    65101 aaaaaaccat aacaaaaagg tatggatggg atggataatt atgaaattgc ttcatctgca
    65161 gtattttaaa aaagtattcg aaacaaaaaa tgttacccaa gcagccaaag aattatttat
    65221 ttctcaacct gccttgagcc gtgcgatcaa acatttggaa aacgaattag gtgtcccttt
    65281 gttttaccat agcggcagaa acattgagac gaccgtttat gcagaagaat tttatccata
    65341 tgcagtcaag acattagaca cattagaaga aggaatcaaa ttattgtctt cggtcaatga
    65401 gaagatcgtt acttccgtca tattgtattt agaggtagcc tctgtttcta ttccgaactt
    65461 ggtccgaatt tttatggaaa agcatcctga tatccaatta acgatcatgc aacatcattt
    65521 accagatgat attaccgatc ctgtactgta catcacttcg gagatgaagc ctggcatgac
    65581 caatattcct atcatgaaag aacctgttta tgtcgccatt cctaagaaac atcctcttgc
    65641 taaaaaagaa catctgcaat tagaagatat ccaacgcacc cccatcttga tgctgtcaaa
    65701 gagcaacgcc ttccgtcata cactggatgc agcacttgaa gcgaaaagta tcgaattgac
    65761 gatcagttcg acgacagatg atcctgcgac attacgttct attgtcaagc aaggattagc
    65821 tgttagcttt ttcccaaaag tttcttggtc ttacgataaa aatgatcctt tcgtcttgcg
    65881 ggaaatcaaa gatttgccct tgacacgaac aatttattta tcttctagct tcacagaaga
    65941 tcatcctttg atcaaaatga ttgcaaaaac gatgcgggaa ttttatttag gaaaataaaa
    66001 aaaaaagagc tgggacaaaa ttcttgtcgc agctcttttt tcgaacaaac ggtgttccag
    66061 aagtaatttc ttagaaaata agccgaaatt tcccaaaaat ttgagaagca attttcgtaa
    66121 attccttctt atttcttgaa gctaaacatt tctgtcacaa cctcttctct attgtcctag
    66181 acattcattg cgttgattta aaacttccat caatcaaatc tgctagttca tctagctttt
    66241 ctattttacg tagatcaata gagatccaat gttctttatt catgtgatag gctggaaaat
    66301 acccctcttt tcctcgcaaa attccgccaa gttcaggatc gaccttcaaa tcaagaatat
    66361 tgatgatcct atggtcactt gcatcatcat agattttttc ttctggaaca gacatcagga
    66421 ccccaaacca ttttttgctt ttttgatgtc tgaatacgca ataatcagga aattttttaa
    66481 aaatatattc tggagacaaa ttgtatgttt cattgatgtg atcgattagt tcttttttcg
    66541 ttagcatctg cttccatctc tttcttattg attcgcttta ttcaaagata ccacgtaaga
    66601 atagaaaaat gaatacaagt agttgctaat caaatacttc gatatttttc ttttttatca
    66661 actcttaaat gttcaatccg cctgtgttgg tcttgctacc atctactatt aaaatgttta
    66721 ttattgtttg cccacctatt ttttgatttt agtggtatca tttttcaagt tcatgatgaa
    66781 attcttatca tcagtaaatg ctccagaaaa ataaacaatg attgaaaaat cagttgaaac
    66841 ttgaccaccg tttattttct ccgtattctt agaatagaag ggagtctgat tgatgtattc
    66901 actaatgaaa aaaatcatta ccgaaaaaga tattcgacgt catgtttctt tagtagaaca
    66961 attgctgaat catacaaaga taaccgtaaa tgaattagct gaaatcatag ggacaaccga
    67021 acgaacgatt ttttctgacc ttcaatctat tcgctctcag ctgcccgaag gctgggacat
    67081 catcagcgat caagcaggaa tcagtttgca aaaccagcaa aatttattaa caaatgacct
    67141 ttgggagatt tttttcaaac aatcagtcag tgtcgaactg ctgaaaaatc tgctttttac
    67201 aaaaaaagtt gctgtccctg attttctagc cgaccatggg ctttcttatg ggacattgaa
    67261 aagacatgtg actaaaatca atcagcgttt agcaagttac gacttgcaga tcgatttgac
    67321 gaaatataca gcttgtattc ttggaaaaga gcgtgcgatt cgtacttttt atcatcgatt
    67381 gctgattcct ttcactcata acaactattt tttcgaggat tattcgatcc atgaatccca
    67441 ttattttcaa tttttaagaa acctcagtca aactgaacta gcggttgaaa cagaagagat
    67501 tttcggaaca tgttggttct ttatcaatac gatccgtata aaagcgaatt gccgattaga
    67561 ttcttctatc cataccaaca gcacactctc ctccctgtat gactctgcat tgaaaaaatt
    67621 gtatttaacg gaaggtattt atcttaaaga cactgagctt tcttttgctt ctttctgctt
    67681 tctggaaagt tggaattaca acaataacta tggacaagaa accgctcgct gcctgcatca
    67741 ttctccattt ttagaggtcc tcgaaacgtt tgtagaggaa ctagcttcag agctgtctct
    67801 tgatcaacta aaaaaaacat ctctgactga taacttggct ctcctcatat taaaatatca
    67861 tgaatcgccg atattgattg aagcattgga ccgtcaatac catcgttttt tagaaacata
    67921 tgatcagcaa tatgcacact tgtatcaaca gaaagagaat ttactgaacg atctaaaaaa
    67981 agaaatagaa atcaatgaac caaattactt tctccaactc ttgtctctac tgatccaaca
    68041 aacgattttt tctatcaaac cgaatttgtt caatgtctat tttattttcc aaggagaacc
    68101 ttcatggaag gcgttcttgc agcaggaatt aaaagattac ttaggaaaac gtgtctgctt
    68161 cttacctatc gaactaaccg atctttccac tatttctttt gaaaaaacag atatcttgat
    68221 ttccaatttc cctctagatt ctctagatat ccctattgta tacatttctt ctattccaac
    68281 gaaaaatgag ctcaatcgtt tgactgaact cactttcaaa acttttttat agtaacggct
    68341 agcgactgta ttctctagct gttttttctt ttttgcgaaa cagtttgttc atgatccctt
    68401 tttctatttc tacaactaag aatagaagaa tcacatttgc tccaatcaat aactgttgtg
    68461 tcatcgttaa acttactgta ccgatcagct gctggccgac tggtagaaaa ataaccatcc
    68521 cttgcaataa agcaaggata cctaatgaaa gaaaaagcgc tttgttttgc aaaagacctt
    68581 ggttcaatga cggcttggac aactctctgc aattgatcat gtaaacagct tgagctaaga
    68641 cgatattttg cagaagaatg gtttgctgta agctttgccc ttcaaactgc atagccaata
    68701 aataggcagg aaccatgatc agtagggaga catagatgat ccgaaacaaa tgataaccag
    68761 ataggattcc ttgctttgga tctcttggtg ggcgcttcat gatttctgga tctggcgact
    68821 cgaaccctag tgcataagat aaagtgattg tcgttaccat attgacccat aaaatctgta
    68881 ctggggacaa aggtagcggg cgattcagca taagtgccca aatcaagatc aatccttgag
    68941 ctaatgcagt tggcaagaag aaattgatgg ttttttgcaa attatccaaa atccgccggc
    69001 cctcttttac ggcttttgca atcgtatgga aattatcatc tcctaaaacc atatcagctg
    69061 cctgtttgct tacttcacta cctttgattc ccatagcaat tcctacatcg gatcttttca
    69121 aagcaggtgc atcatttacg ccgtctccgg tcattccgac gatttctcca tttttctgca
    69181 aagctttaac aattcgcagt ttatgttctg gtgtcgttcg agcaaagaca tcgactattg
    69241 gcacttgctg aatcaactct tcatcagaca taagatccaa atcgatccct tctaaaactt
    69301 tggcagtatg ttttaagcca atttgttccg caatcgcttt tgctgtgtct ttgtgatccc
    69361 ctgtaatcat tttcactgag atccctgctt gttggcattc ctttacagct ttgactgcac
    69421 tttcttttgg cggatcgatc aatccggcga tccctgcaaa agttaattgg gttaaagtct
    69481 catgcgtgag ttcctgtttc gaatctactt ttttataagc aaatcctaaa acacgctgac
    69541 cttttctcgc aaattctgca gctgtctgac tccatgcttc ttgttctgca gaagaaagag
    69601 ttgatttagc aaataatact tctggtgcac ctttgacgta aatcaccgct cctttttcct
    69661 ccgcatgcat cgttgccata tatttgtatt cagaactgaa cggaatcttt gcttctattt
    69721 ttttcaaagg tagattggct gtttctgtgt gtcgaatcag cgcaacttct gtcggattgc
    69781 cacttaaatt ttctgttttc tgttcttctt ttgtttttaa ttcctgacag tttttcataa
    69841 tggacaacac gcaggcttct tcttttgcag ctacatccac aactgtcatt tcattttttg
    69901 tcaatgttcc tgtcttatct gaacagatca ctgtcataga acctaatgtt tctaccgaag
    69961 gaagtccttt gatgatcgcc ttttcttttg ccatttcatg tactccaacg gatagaatca
    70021 tggtcaaaac agctggcaat ccttcgggta ccattgacac caccaaagca atcgtagccg
    70081 aaagaagaat atgccaatcc ataccatatc gaaatgtcgt aaaaataact aagaataggc
    70141 tcaaacaaag aatgccttga aaaatttgtt tgtttaatcg gttgattttt ttaatcagag
    70201 gcgtcgtttg ttgttcgacc gattgcaatg cttgattgat tttaccgatt tctgtcgtgt
    70261 ttcctgtttc tacaacgaca ccgactgcag aaccagattg tacaagcgtt cctgaaaaac
    70321 ccatattttt ctggtcgccg atcgattctt cttctgtcaa aacggcatga cttttttcag
    70381 atgcttctga ttctcccgtc aaaatcgatt cttccactaa taaatcatgt gcttcgatta
    70441 atcggatatc tgctggaacg acatctccgg cacgtaagac aatgacatct ccttttacca
    70501 gttctttcgc agggattttt tcttgcatcc cgtttgatag tactatcgct tcttgtccca
    70561 tcagctgctt caaaccattc aatgattctt ccgcttttct ttcttgccag taactaacga
    70621 gtccattgac gatcactacg aataaaataa tacttccttc aatatattca ctagaagcaa
    70681 atttcaaaaa agaggcaatg atcaacacga tcatcagcag atcagtaaaa tgctttgcta
    70741 tttttttcca tcgttttgtc tgctgccttg cttttatttc attatatcct tgatcagtca
    70801 ggcgtttctg tcgttcttct tgcgacaagc cttctgttga tgtttgatag tttttcaata
    70861 catcttctac cgtcaatctg taccagttca tcctatcccc tcctgtttaa ttgatactgt
    70921 tattatacgc agggaagttt tttcaggcgt atcgattatt tcaggggggt ctgaaataat
    70981 tcgttttgca aaatgtatct gggcctaact gatatttcta ttgcttattc ttttatatac
    71041 aaaatttaag aatacaaacc agataaccaa taaaaaagga ataaagcgtg tcgtgctttc
    71101 gaataacaag ctgaaagcaa ttgaagtaaa aaacaccaac aaagcaagat ctttatatct
    71161 ttgtgtagtg ttccgtttct tttctttaat aaattgaaca tgtgcacaca agatcgaaga
    71221 ccacacaaat agaaaacaac tcgttgtcat gcctgccaaa agctgaaaaa acaatcgact
    71281 atcagctaca aaaaaatgta gacaaagacc ggcaaaaaat aacattcctg taattaaaat
    71341 accgtgtaaa ggtacgcctt tcttagaaag cgcacaaaac caatggggca aacttttttc
    71401 ttttgctgtt tgatataaaa tcctgctagt actgtagact gcactatttg ctgaggacaa
    71461 agaagcaacc aaaatcatta gattgacaat tgctgctccg ccttggcaat ggatcacttg
    71521 cagcatagtc actaaaggac tttcttttaa atctaaacaa tgccatggaa caacaaataa
    71581 aatcgacaaa atcgttccta tatagaaaaa gagaatacgc caaggcagac agttgattgc
    71641 ttttttcaaa ttcttttgcg gatcacttgt ctcgccaacg gttaagccga tcatttcaat
    71701 tccagcaaaa ctgaataaaa ccataggaaa tgagactacc attccagcaa agccaaacgg
    71761 tagtaattca tcgatctgtc caaaattttc tttgattccg atagactggg tatgaaaatc
    71821 tgagacactc aatcctatac ccaataagat aaaaaggaaa atccccaaga tcttgatgat
    71881 tgagaaaaaa gattccaatt caccaaacca cttgactgca acaaggttga ctgccattaa
    71941 gatcattagt gcgctacctc cgcttatcaa agctggtaca tgtacaaacc agaaatggat
    72001 atacaatcct attgctgtta attccgcaag tccagctcca agccagcaaa gccaataagt
    72061 ccaattgaca aaaaatgccc actttttgcc taaataatag tcaacgaaat cactgataga
    72121 gttaaatgta ctatttgcta aaaataaatc acccatggcc cgcatcaaac cataaatagc
    72181 caaaccgcat atcaaataaa cgagaataac agctggccct gctgatgcaa ttgcctttgc
    72241 tgaacctaaa aataatcctg ttccaattgc gccacctaat gcgattaact ggatatttcg
    72301 attagttaga gtccgtttca ttgccggttt ttccatcaag ttcacctttt tctttttcaa
    72361 gcagcatggc gacttcctgt tcccaagaag gtttctttat tttttcaata cagagtggta
    72421 ctacaaacaa aatgacactg atggctgtga ctgcaattag attgatccat gttccagctt
    72481 tcatcgtcag tccgacagaa aatccgattg ccgcaaataa aacaataacg acagtccaaa
    72541 ctccaagatt gctctttttc tctttttttc caattctaaa tggtcgattc aactttgcat
    72601 gtgtataacg caatctcaaa actgcgatcc ccatgatgac atagacgata cagtagataa
    72661 cagtagttga atttacgagc atcaaaaatg cttgattgac gccaggaatc agcaaataaa
    72721 aaagtgcaaa gattgagata atgacagact gagtcaaaat aacggatttg gatacgtcaa
    72781 attgattcgt cttccaaaaa ttgaattttg gtggatacgc accttttcta gcactttctg
    72841 tcactgtctt tgctggtcct gaggcccaag cagataattg gactgctaca ccaatgaaga
    72901 caagtaaact aaacagattc acaataagat gtggcaaacc aagaatttgg caataaatcg
    72961 aaatagattg cgcgatatta ttcaattcca tttgtccttt tggtacgaca tttgctacaa
    73021 ctaaagcatt caaaatattg acgaaaaata taaaaattaa cgcggcaaat actccgcgaa
    73081 tatacgtttt aactggattt tccaatcgag tgatatacac agaggacatt tcgataccag
    73141 taaaaataaa catgatcggc gcaaaataaa caaatgagga tgcagtcgta gtatctggta
    73201 ttaatttgtc ccatgaaaaa ctgcctaatg ttccggttgg tacgatccca actttgatcc
    73261 acgcagcaaa ccctaataag agcatcatcg tcaaaggcac gtacaatcct aaccaaacac
    73321 cgacttttcc gccgattttt gccatatcaa atttcaaatt caaaaaagtg atgatccaat
    73381 aaacgactaa aatgacaact aatgtaaatt tgctgttcaa accaagcggc acattatcga
    73441 taatattacc aaacaacgga gcgagtgctg aagcgaccat caccatccca ggaaacattt
    73501 ggacccataa cagccatgag acaacgaacc cccatttttt tcctagagca ttcgataccc
    73561 aaagttctgg accacctttt tggggaaaca ttccagcaaa ttcaccagag atcaatgaga
    73621 ttggaaaagc gtacaataat actgcaacca gcatgtaaaa aatcatcgtc cagctcgttg
    73681 ctgctacatc tggaatattt cgtacacttg ctacaagggc gcaggtcatt ccgataaagg
    73741 tcatggtcgt gatttgcttt gatgaaccag tatctttcat ctttattcct tctttcaata
    73801 gcgacatatg tttttgtttt cttttatttt tgttcaagaa cagaaatgac aaggtttcat
    73861 cgattcagta caaaacccag tatcaccgaa acatccattg aacgatctta gtgaactggg
    73921 tttgatacat gaaacgaacg atccaactta tagaacgttt tataaaaaag aatatcttgg
    73981 cgaggaatat atgaaaaaca gggggaaata caattgtttt gatgaagcaa ataattgtct
    74041 gttctccata tgtctcttgt tattctttca cacaaaaatc agttctattg gatgatttcg
    74101 tttagtttct tttccattgc tttggcgatt ttttttgtat aaaaattgaa aattcgatca
    74161 tcattcaaat aaggagtcat gatagccgca cgtagcagag tgattttctg ttcttttttc
    74221 cattcttctt tcgttagacc cattctttca acaaaacgaa tcggagaatc accgtaatct
    74281 tcttgtgtaa atgtagtatg agaagtaata aaccgttcac cataaacatc gccatccata
    74341 taagaagacc gatcgaacat tttttcattt aattcattga tagcgttcaa atctgtacag
    74401 ccttgttctt tgaataccca attgaccata ttaaaatcag gatgattcaa tggatagact
    74461 tcgattgttt ttcctttaac agtaaaagtc agatgatcga gaaattctct gaatctttga
    74521 gctgcctcga ttgaagcccc aatcaattga ccatatccgg tcacattcaa tggcaataca
    74581 cgatgtgctg tccagactgc ggcggcggtt gctccagctt ttgatccttc caaaatataa
    74641 gctcctaaca tatctggagc ctttactgat ttttcaaaca catatggcgc gaaataagaa
    74701 atgatatttc tcatattttt atgtttgatt acgattcctc cagcagcata agggacatag
    74761 cccatcttat gaggatctat cgtgacagaa tccgcttctg aaatagctct gaacccttca
    74821 tatacctctt tgtcaatcgt tacgcagtgg tggaaaacat gatgttcttc aaagaattca
    74881 gctaaggaag catacggcac aaattctcct gcttcgttta gaaacagtga acgcgcatag
    74941 ccgccatatg cggcatcaac atgtaaatag aaatagatcc cttcatcttt taacctttct
    75001 cttaattgga cgattttatc tacactgtct acttgacctt cttctgtcgt tcctacgaca
    75061 gcaaccacac ctagaattgg gattttttgt ccagctaatt cacgaattgt tttttccaaa
    75121 gcattaatat ccattcgata atcctcttga actgggatag caaccatctg atctaagccg
    75181 actccgcaaa tatctaacgc cttcatccaa gaatagtgtt ttgtttgagg gaccagccat
    75241 ttccctaatc tttggatatt ttttccgcta cgggaagaag ctgctttgac ctcatccatt
    75301 tcttcgtccg taaagctttc ggtcatttcc aaaatttctt caacagataa attcaaaagt
    75361 tcccactcag acattttttt cactttttca ggcagcactt ccttgacagc taaaggaatc
    75421 gatttgatgc aacgggcgta ccataatcct tcaagattag caatagaacc atctgctgca
    75481 atgtgtcccc atccgtctgt catattgaat aatgaagcaa aatcctgtcc tacttctgct
    75541 tccatttgcg aagttgccat agaagattcc aatgcaacat tatttgggtt ccacagcatc
    75601 gcatagttgt aagctaataa agcaggcatc aatgtttcag cattcatttg tccccagtaa
    75661 cggcctgctg aatgccatgg gatcgatcct gcgcgtaatc gctgactgac ttcatccaag
    75721 acctctatca tatggtcgcg ggtggctaga taatctggag tgagcttatc tccttcgcta
    75781 attgcaggca tatctgaagg aatataattt tctctccatc caagatgttc atctaccatc
    75841 ttgttcaaca acattttata aactggtcca ttttcagctt tgtcgcctat aaagacggcc
    75901 ttgatatcca tatctttcat ttttcttccc tccatatttt gttggtcaat gtcttgcaga
    75961 tacatgtgtt tatctgtaac acctcttcac tatagcgcca aaaatgagaa tttttttttt
    76021 ataacatcaa atccacgtag atttttacaa acaaaaataa ataaagtcgg atttttctga
    76081 taattcaacg caaaaaagcg aacaattttt caataaatca gtcttctaaa atagataacc
    76141 taaaaaaagc gaacaaacaa ataaaatgac tgtccttcat tcactaaaca tatttttatt
    76201 tttttatatt gttaaaaatt cgcaatttat tttttaatag aattatctgt tttccaaatt
    76261 ttataacata aaaaaccttt tttaacggca tttatatgct ttttcagaaa ttaactgatg
    76321 atttcaaaaa gaaaacatgt cataatattt cccatattgt gcaaaaaaat acaaggcgga
    76381 ggctctacta tgattgaaga atatattgag aaaaatattt taagacagct gtttttatgt
    76441 gggcaattct atgtaaataa agaagtcaat ctagaaaagc tctccaatct cctgcatgtt
    76501 tgcaaaacca ctttactcaa tgatatcaat aacataaaaa aagaatttga agaacagatc
    76561 gcttatacac atcgggaaaa ggaccgttac actttatatt tttcagaaca tatacctcga
    76621 tgcaagatca tgcagcaatt gtctcaaaat tcgttgtttt taaaaacttg tctgctttat
    76681 ttggaagaag atgaacctga ttatcttcaa ttaactgaat gtgaattcat ctctgtcagc
    76741 aaagcttatt cattaaaaaa acaagtatta gcttatttta atgactgcgg gatcgaaatc
    76801 gaccgctact cccctcgatt cactgaaatg gaaagacgtc tgctgcttct taatgtgtcg
    76861 tatcgtttag gcggttttaa ttcttgggag ctacctgaat cgttttttga acgtgccgat
    76921 cgtttcattg aatccgtaac ggaaaatagt ggcagatttt atgataaaga aaataaagaa
    76981 atcttatcga ttggttttgc tatcagtttc ctacgccagc aagtgtgtgc tgtgacaata
    77041 gattcaaaat ttatcgaaga aatcaaaaaa cgtcctattt acaattatgt cgaatcagca
    77101 tgggaaaaca ctgatttcca aacctattat aaaaaagaag aattcgcctt tattttgaca
    77161 ctattcaatc tttgtaatta tggtttccat tcttatcagt tgattgcgga agactttcaa
    77221 cagctacacc aagtgtttat tgacaatact cccgaaataa aagaactagt tgctaccttt
    77281 gaatctcact tcaatcaaga attattcgga aaccaaccgt tcgaacgtgc gctgattcat
    77341 ctgatgcgtt cggcttggga taactatcaa ttattcatgc cagaaaaatt ttatctttta
    77401 aatgaggaac agacaaattt atataaagaa gtccagacaa ttttttccag ctggtccagc
    77461 cagttacctt atgatctacg gttgaatcct aattgcatgc gggcttttgt gatcgaattg
    77521 agcggaattc tccgtctgac aaaagaacat ctgactatct atatcgtcac aaattcggat
    77581 gttcattatc tgatttatcg ggaagccttg gaagctgtaa ctactttcga ttttcaagtt
    77641 gcaccaacaa tttattcaag tatatctgat ataaagaagt atgcgcagca gtcctcaaac
    77701 cgggtattat gtgaacgtac attatataca ccagatgcgg tccaatatga aaatattatt
    77761 cctatttcga tcaatacgat cgatcgagct atcatttcag ctgtgcaaaa caaataaggg
    77821 gctgtgacaa aaatcatgtc acagcctctt atttgttgaa gatgcccatt tctgtaacaa
    77881 tctcttgata cacgtcaggc tcacaacctc acttattttg gacatctacg ggtccgatct
    77941 ctttatttaa aaaataagaa atgatggttc ggataactac caacgccgct agttggaaaa
    78001 tatcctgcaa ggtaggtttg ataatcgatt cgatgatccc agctgaaaca agaatttcca
    78061 aacttagaag tatatagcct cccaacatct ttttaatagc attgttctcg ctgactcggt
    78121 cgctttgcac ttttgtatgg acaaataaat atttcaaaaa atccttgatt gatagacaaa
    78181 caccccaaac caataaacag atagcaaaga tatcaagtcc cagtacaagt ttttcgaaat
    78241 atggaagaag aaactgcatc aactctgtcg tcatcctacc tctcctcttc tttgtttttc
    78301 tttgtcttct atttcctgat tcaagaaata agaaatgact gttcgaatga taataataag
    78361 tgcaagcttc aaaatatctg tccaagtcgg cttgataact gactcgatga tatcagcaac
    78421 gactagtact tccaagctta acaaaatata acttgctagc agttttcttg tatctgcatt
    78481 acgagtatta cgttctgcat agtttttctt gacatgagac caatcaaaaa gtttgaatag
    78541 aacaagaacg atcccgacaa ttaagatacc gatagaacaa atatttaaaa tagcaatgat
    78601 ccattctaga aattcaatta aatttgagcg aaacatatac gctacctact ttcttttaat
    78661 ttgttcctat tcttttattg taaaagaaag ttaccttgtt cgtctattta aaagttgttc
    78721 taatgataac ggttcgctta aatttttctt tttcactctc ccatttttct ccctccatcc
    78781 ataaatcgtg gaagtatcca aaacaacgta gcaagttaaa ataaggctta gtccgtcatc
    78841 agcttttcaa agaagcactg tctcggtgct ttttttgtac ccaaatttct aaaaatagaa
    78901 ccatacacct cctcaaatct tttcttctta cctaccctat ttttatttac aggaaaatca
    78961 gacacttctt cttttttgtc aaaatttcct ttttcttctc gtcctatcat ttggcattct
    79021 aataaaaacg aactatcctt ggatatagaa agagaaaaca aggaggcgtt tttcatgagt
    79081 aaaaaattaa tcaaagtcgg catcggttta ggtttgcttg cccttggcgc tgcatatcta
    79141 ggaaaaaaga caggactatt cgaagatgac agtcatttat atgatgaatt cgaatcaatc
    79201 tagcatccta tttagttgaa tcactacgga catacttgga agacattgga ggaatcacaa
    79261 tgagaaaaag taaagcaata atgattggtg ccggtattgc caatatggca gcggctgttt
    79321 atttgattca agaaggcaaa tggaaagggg atcagatcac cttttattca ttggatgatc
    79381 acggttcaaa tgatggtgca ccgaccgaca ctgtagtgga tgaatattgg aataaaaacc
    79441 atccattaga aaaccaaaaa ggctatattg ctcgaggcgg tcgcatgctt aattaccgta
    79501 cctatgtaga tttgatggat ctgttaagtc gaataccttc tgttactgag ccagggatga
    79561 ctgctgaaga agatacgaga gattttgatg caaaacaccg aacctttgac aaagcacgtt
    79621 tgatggaagg tggcaaagga atcattgatg gcggaaaact gggattcaat aataaagacc
    79681 gtattcttct gactaaactg attgctatgc ctgattcaga agaagaaaaa ctagacaata
    79741 tcactatcga agaatatttc aaagatgatc cacacttttt tgaaacaaac ttctggttta
    79801 tgtgggaaac aacatttgct ttcagaacac gtagttctgc tcaagaattg cgtcgctata
    79861 tgcatcaaat gatttatgaa ttcactcaaa tcgaacatct agtgggcgtc aatcgaacac
    79921 gttacaatca atacgaaagt attatgcttc ctttgatcga gtacttgaaa gaacaaggat
    79981 gcaaaatcat tttgaaccgc cgtgtcactg actgggaatt caaagaaaca ccgatgcaag
    80041 atgaaatcac tgtgactggt ttgaaaatta ccaatacact gactcaagaa gaagaatacg
    80101 ttgtggtcga tgaagataca gcagttattt tcactaatgg gtccattaca gattcagcta
    80161 ctttaggaga ttacgaaaca ccagctgtag aaaatatgga ttatggtgca gcttctagtc
    80221 tctggaaaaa agccagtgaa cgtttctaca acttgggaaa tcctgacaaa ttctttgctg
    80281 atcgagatgc aagcgaatgg gtcagcttta ccctgacgac gaaaaaccat ttgttgttga
    80341 atgaaatcac ccgtatcacg actcaagaac caggaaatgc cttgaattca tttatttcaa
    80401 ccacaccgat cacgccgtta ggccaaaaag atgtcaatat gtctatcgtc gtgcatcatc
    80461 aaccgcattt tacgtctcag aaaccaaatg aaacagttat ttggggttat ttcctttatc
    80521 caagacgacg tggcgaattt gtggataaac agtatattaa aatgaatgga aaagaaatgc
    80581 tagaagaact gattggacaa ctttcaaaag tagatcctgg accagtgaat attcgtgaaa
    80641 aagaaacaga aattttcgac agcgtaataa ataatatccc tgtctatatg ccttatgctt
    80701 ccgcgttgtt caataatcgt gccaaaagcg atcgaccaaa agtcattcct aaacattcga
    80761 ccaatctggc ctttacagga gaatttgtcg agcagcctta tcagatgatc tttactgaac
    80821 aaagtgctgt acgttctgga gaaatcgctg ctttccattt tgcgggtatt cctatgtccc
    80881 gtcttgtcaa aacaccgcgt tacgacaaag atattcctac tctagctcgt gccgcaaaaa
    80941 aaatgtttga ataatcaaga ggttgtgaaa aagctgccct gcatcaagta ataagaacaa
    81001 ccaggctaaa acagcttctt atgtttttga tttggttgga cttattaccg cagatgcaag
    81061 cttttgaaca ccgtttacca agaggttgtg aaaaagctgc cctgcatcaa gtaataagaa
    81121 cacccaagct aaaactgctt cttatgtttt tgacttggtt ggacttatta ccgcagatgc
    81181 aagcttttga acaccattta ccaagaggtt atgaaaaagc tgccctgcat caagtaataa
    81241 gagcagccaa gctaaaacag cttcttatgt ttttgacttg gttagactta ttaccgcaga
    81301 tgcaagcttt tgaacaccgt ttaccaagag gttatgaaaa aggcgtttag tttcgagtat
    81361 gaagaaaaat tttgtgaaaa tggttcctca cgtttttgca taaatttgac ttaataccga
    81421 gaaactgatc ccttctgtca taacctcttt ttatttatgt ctgtttcttt ttgaaaacaa
    81481 ctattttttc aacgtttact ctcttgccaa tccaacatca tctaacggat acaactattt
    81541 caatgattac cattacacta aaaaatcgga aacacacctc tccgaacaca aatacataag
    81601 actatagaat gtttcattta agaaaaaaag cgtttcatta tcaaaaaggt aagatctcct
    81661 ttaaaatgaa attatctgta gtactaataa tgcagacaat tttatgaatc tgaaaggagc
    81721 atctccaatg aaagcagtca cttggcaagg aaaacagaaa atggaaatca gaaacgtaga
    81781 tgatccaaaa atattagaac caacagatgc aatcatccgt atcacagcaa cagccatttg
    81841 cggctccgat ctgcatcttt accatcatgg tgaagcagtt ttggaaaaag ggtatgttgt
    81901 aggacacgaa ccaatgggaa tcgttgaaga agtgggatct caagttcaaa cattgaaaaa
    81961 agggcaacgt gtggttatcc cttttaatat tagttgtggt cattgtcatt tctgcctgaa
    82021 tcacatggaa agccaatgtg atgaatcaaa tccagatcag ttatatggcg ggcttttcgg
    82081 atttggcaag ttgaacggta atcattgggg tggtcaagcg gaatatctaa gagttcctta
    82141 tgcagactct acttcatttg ttgtaccaga taatgatctt cctgatgaaa aagttttatt
    82201 tctatcagat attttgccca cagcttattg gagcgttgaa aacgcaggag taaaaaaagg
    82261 cgatacagtt gtgattctag gttctggtcc agtcggtcta ttcgctcaaa aattcgctgt
    82321 tatggctgga gcagagcgcg taatcgcagt agatccagta cagcaccgtc tagataaagc
    82381 ggctaattac aatggggttg aaacttattt cttagaagac acggcacaag ctggaacaga
    82441 attgtatgaa ctggctaaag gtggcgcaga tgtcattatc gattgtgtag gaatggacgg
    82501 attagagcct gtcaaagaaa aagcgaaaaa tttagtaagc ttacaaagcg gcacaatctc
    82561 tccattacag atggcatcgc aagctgtcaa aaaatttgga acagtccaag taactggtgt
    82621 ttatatgact ccagcttctt cttacccgct gcaagaattt tttatgcggg atatcgctgt
    82681 caagcatgga caggcaccaa ttatccatct aatgccaaaa atttacgcaa tgattgcaga
    82741 aggactattc gatcctacac aaatcattac tcattcgctg ccactatcag aagcagcaca
    82801 agcatatgag atctttgaca aaaaagaaga taaaaatata aaagttgttt tgaaaccttg
    82861 aattcagtaa aaaatacagg tgattttctt tatgcccaaa atcaaacgaa atacccatga
    82921 gatcgaaata ggaaaagaag aagatatcga aatacgagga cgtcgcttcc gcttctattt
    82981 ccaaaatcgt tacacattga tctcactggc tgtcgattta ttaaccggga ttttctatat
    83041 ttttggaagc cttgcttcct taactaaaat ccccgatcga tatggcacct atttttattt
    83101 ggctggtgct attttcttga cgattcgtcc tattctcaga atcgtaagga acatttttat
    83161 ttacgacgaa aaaaaagcaa tgaagagaac aagcaaaaaa aaagaggcat gagaattttt
    83221 caaatctcat gcctcttttt tcaccctatc gtatcacttt gatacagacg agcggtcgtc
    83281 ccactttctt ccttgaccat tgtcaaaaat gtccactcgt atcgttcata aaacgtggta
    83341 tgatctgtaa ttaagtaaag tttttcgtac ccaagttgat gcatttcttt tctgatttcc
    83401 gctaatatcc gcttggctat cccctgctta cgcttttccg gttcaacaaa cagggcacaa
    83461 agatttggtg tcagatcagg gcggttatgg aagtcgtttt caatgacgcc cgctcctccg
    83521 acgatggttt ctttttcatc taagaccaca taccattgag gaatactttc cttattagcg
    83581 attccagtac gaatactttc ctcatacaca acagcaggaa ctccccattt tgatgaaaac
    83641 caattcgcgc tttgttttac taattctggg tgttctctta atttgatcca gttatatgta
    83701 accaatgttt aaacctccga ctaaaataaa acgtttacaa aaattataca agtctttatg
    83761 aaaattagca atgacaacaa tagtgatgta aaaaaaaaac ggaaaacaat cacttgttct
    83821 ccgttttttg attaatcaag catctaaagc ttcttttctt ctttcttgga tcgtagctac
    83881 cttgacgaac ggtagataga tcaaaataga aagaaccaaa ttgacagcgg ctagtacacc
    83941 acctgcaata ctttttgttg ccaatacacc gccaataatt ggtggagtta cccatggagg
    84001 cataacggta gctgctggca ctaaacctgt agaagtcgca aagtaagcaa cactaactaa
    84061 gaccattggt gtcaaaataa atggaatgaa catgatcggg ttcaacacga taggtaaccc
    84121 aaacatcgtt ggttcattaa tattgaagac acctggcgca atcggcaagt ttgttacaac
    84181 catatatggt ttgtttttac gtcctactaa ataaatagct aacagtaaac ctaaagttgc
    84241 acctgttcct cctaagttga caaagctgtc aaagaaaggt ttgttcacga taaacggtgc
    84301 gctatgccca gctgcgattg cattaacgtt tgcttcaatg gctggcgcat tgattgtttg
    84361 catcaaagga tcgaccatat tcgctccgtg taaaccaaag aaccataaga atggtgtgat
    84421 aaatgcaagc agtaaggcag atggataaga gtttgcaagt cccataaatg gttcttggac
    84481 cactgtatag aaagaaccta cgatatcatc aacaccgaat gcagcaaaaa ttgcagcaac
    84541 taaagcaaac gcagagatag tgatcattgc tggtagtaat gaagcaaatg cttttgcaac
    84601 tgccggtggc acaccatcag gcattttgat gatcaatttt tcatttccgc ttaaacgtac
    84661 aaagatttct gttgaaataa tcccaacaat aatagcaata aacaaaccgt ttgagctcat
    84721 acctaatgct ccgcctaaag cgaagaaaga gcctaaagaa atcacacctg cggaaacacc
    84781 gtcttttcgg tagccgttag ctaaatgata agcaagcaag aaagcaatca agacagaaag
    84841 aatggcaaat gtaccgttcc aagcagcagc cccgaatcct ttccatgatt caccaccaaa
    84901 aattgagttc atcaattctt ggaacccggg aatcggtaag ttattgatca ttactgctaa
    84961 tgctcctaag atcattaacg gcatactcac cataaatgag tcccgaatcg caactaaatg
    85021 ccgttgtgca ccaatttttg atgctacagg tataaaatgt ttctccataa atgcaacaaa
    85081 tttatccata aatcttccct cttttcttta ctgtagatta cgcgttcaat cgacgataca
    85141 gatcaatgat ctcttttgct aaatctgtaa aagctataga tgtcatcaga tgatcttgac
    85201 tgtggaccgt caaaagcgtg acttcaacgt gatttccttg tgcttcttgt gtcagcatct
    85261 ctgtttgaga gtgatgtgct tggactaaag attcctctgc atctttgatt ttttcatctg
    85321 ctaaagtgaa atcacctttt ttcgcagcag caatcgcttc cattgcatcg ctttttgcat
    85381 ttccgccaaa catgatcaga cccatgatgg cttctagatt tttttgatct tccatttatt
    85441 gtatcctccg ataattttta ttatttgttt attagttttt ctgcttggtc gagtactttt
    85501 tcaccattca tcatgccata gtcagccata ttgattacat ctaaaggaat gcctttaggt
    85561 gctagctttt cagcaaattg attttgcata aagcgtactt gcggtcctaa aagtaaaacg
    85621 tctacatttt tagattctag ttgattatcc gcatctgaag cagatacagc aaagatgtct
    85681 gcttccattc cttttgcttc tgctgccttt tgcatttttg tgactaggag acttgtactc
    85741 attccagctg aacatacaag catgattgtt ttcttttcca ttttaaacac gttcctttct
    85801 atacttacac ttgtatataa gcaagtagcg tgccaacttt aaaagcgctt taaaaagttg
    85861 atatcatcac atttaaggtc tataccaagt tgcatacaca ctaaaaaaga aagcgcacac
    85921 taaacacaca aattaatttt tattaccttt tttcttttaa cgtgcacaaa aaaagttgtg
    85981 acacaaaact tgtcacaact tttttcaaat aaacggtatt caaaagcttg catctgcggt
    86041 aataagtcca accaagttaa aaacataaga tgttgttttt actttgctat tcttattact
    86101 tgatgcagga cagctttttc acaacctctc aataaacggt gttcaatcag ctgaccctgg
    86161 gtattagctc aaaacgctgg attcacaacc tcttttattt caaataacca gtaaatacaa
    86221 tgaacatcta caaaaaactt ctatttattt atagatttcg tcaggcaaat ccaattctct
    86281 cttatcaatc aaagtctgat accacgaagc agattttttc aatgttctgc ttcgttcatc
    86341 gttcaattcg attcgaacta atccatatcg attcttaaat gcattcattg gtgacacaca
    86401 gtcagtgaat gcccataaca tatagccttc gcaatttgcg ccttcttctg ttgctttgat
    86461 caagtaatgc aaatgctgtc cgataaattc gatacggtaa tcatcttgca cgattccttt
    86521 ctcatccata tactgttctt catattctct tcccataccg ttttctgtta tcagccaagg
    86581 gatattatga taattttctt ttagatacat ggctatatca tacatgattt tcggatagat
    86641 ttcccatccc ctggaattat tcattttctt cccaggtaaa tcaaagactt cataatatcg
    86701 ttcaggatgg aaaggtgtct cttcattcca ttgataacga ggggcgcgaa cgcgtttagg
    86761 ataatattga ttgattccaa ggaaatctac tgtatgatgc tgaatcgttt ctaaatcctc
    86821 tgttgcagga tcgaaataaa tcgattgttt ttgacacaac tccaggaact cttctgtgta
    86881 gtatcctttt accatcggat caaaaaatac tcgattataa aacaaatcat acatataagc
    86941 agctttttgg tcttctggag aattggatcg agcatagacc atttcaggat ttaaaataca
    87001 gccaatcctt ccaccataat ttccgctgcg gtaaatctct actgctttag ccgttgctaa
    87061 aactttatga taattccaca tcatccactt ttttgtgttt tgttcatgcg gccagcgaac
    87121 agcatccaaa tagcaacgcg tttggggaac gattggttcg ttgaatgtaa accagttttt
    87181 taccctatca ccgtaacgat caaaggcaat ttgagcatac ttagcataaa aatcaactac
    87241 ttttcttgaa gaccagccat catatttttc caaaagaaaa gctgggactt cataatgttc
    87301 caaacaaatc atcggttcta cgtctgcttc gatcaaagag tcgatcattt cacttatatg
    87361 ctgagcatat tcttcatcta ctatacagtt ctcataatca gtaaaaaaac gagcccaatt
    87421 gatagaagtc cgataatgtg tcagatggat ggatttcatc agatccacat cctgctggta
    87481 ttgttccata aaattagttg ctacggctgg gccataccca ttatgccaaa caaaatgttc
    87541 atttttatac cagctatcta taaacgaatc ctgtccttct ttttttcctt tccaaccttc
    87601 cgtttgccaa gcagaagatg cagcaccaag aataaaattt tttggaatag taattttcat
    87661 gatttcctcc tgttttttag atcccatcat tttccacacg atttgctact tttacaaatg
    87721 gcagatagat caaaatagaa acaataatac aaacaagttg cgtaataact gcaccgatat
    87781 ttcctgctgt tgccagataa gcattgacga tcggcggcat tggccaaggg accattacaa
    87841 ctgctttcgc cgcaaatcct aaagcggttg caaaataacc aatcgttcca gtgataagag
    87901 gcgttaagat aaacggaata gctaaaattg gattcagcat gatcggcata ccaaaaataa
    87961 ctggttcatt gatgttgaag atcccaggag caagggataa cttggtgatt tgtttcatat
    88021 cttcccgttt tccaactaac aatactgcaa tcagtaaacc gatcgtgact ccagacccgc
    88081 ccatactcat atacatatcc caaaatggca tagtaataat gttcggtact tcttttccag
    88141 cttcaaaagc ttccgtattt acagcaattg ccgctaaaag caacggttcc cgtatcggct
    88201 tcaccatttg atttccatgg ataccaatca cccaaaagac ttgcgcaata aacatcaata
    88261 gcaaaatacc cggtaaccct tgtacgacac cttctaatgg gcgttgtacg acattgtaaa
    88321 tgatatcata aaggtacatt cctgtaagtt ctttgatgat aaatcccgca gccgcgatac
    88381 ccgatacagt cagaatcgtc gggaataaag cagaaaaact agcagaaaca ttcgttggca
    88441 cggtatcagg cattctcagc tgtagtttct tctgtttcct caaccagcaa taaagttcaa
    88501 tagaaaggat ggagaccaac attcccaaaa ataacccttt cgtatctgta tattgtttag
    88561 ccaatacgtt ttctactata acagtctgat tttcattcac taattcataa acagttggat
    88621 taacagataa ataagacatc actgcgatga taccagggaa tacaccatcc actttattca
    88681 gcttggctaa ttcgatccct atcagaaaaa cagcatagat ggtcaagaaa cttagtgtga
    88741 catagctgat ggcagatgcg ataggcttta attcttctaa aaaacgcaag aaacttatct
    88801 gtgctaagcc attttccgag tcaaagacca ttgctgaaaa caatgtgcca aaagcacccg
    88861 taataattac cggaatcaat gcagcaaatg cgttttttat caccatgata taccttaaat
    88921 tattgattct cgttgccacg ttccctaaaa cattggctaa tttatccata aaactcattc
    88981 cagatcccct cattcctgct tcttctcctt gacgtcatct ctttttgtct attagtcagc
    89041 gcttacattt cgatgaacag aaactattta ctcctctttt ttaccaaata taaaacaaaa
    89101 attcatctga tgtatttatc ataaaataca tcagatgaac tgtcaattag tttctttttc
    89161 tcctattatt ttctgtaatt ctctccgatt tattgccata tggacagtca ttgcatcaaa
    89221 cgcagcaagt gcattccgcc tttcgatggc ctgaacgatc tctgtatgaa tatcgatcgt
    89281 ctcgattttc agatgctgga tatcataatt tttattaaac aaagcaattg attcattaat
    89341 gattgggata atatgcagca aggctacgtt tccgctagct tctgcaatca tcgtatgaaa
    89401 atcgatgtct aattgaacat gttcttgtgt gccttctcga aaagaagttt caatcttttg
    89461 cgttaatttt ttcatttgga cgatttgatt cttcgttgca tattccgctg ccaaacctgc
    89521 catcttaggc tccaataaat atctcagttc aaataagtct cgtatcatcc gatcctgatc
    89581 ttcaatcaaa gaaaaaccga gtgggtcatt ggcaatccct cgcttatcac tgacaaatgt
    89641 ccccgctcct tgccgaactt caaggatatt cctggaagct agagcccgca cagcttctcg
    89701 caccgtgctt cgccccacct ctaaataatc ggacaattca tattcattcg gcagtttatc
    89761 tcctacttgc aactgcattt cctttaaata tctaaggatc ttgtcagtag ttacttctac
    89821 tagggtttta ttttcttcca aaccacatac ctccttttca tctgatgtat tttttcgtaa
    89881 ttattataac acgtttgaat catctgatga ttttttgtat acaaaattga ttaatccgtt
    89941 catagacata caaacgaaga agatatttac cataaaaaag actagga
//
LOCUS       DADQDV010000003        82819 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.003, whole genome shotgun sequence.
ACCESSION   DADQDV010000003 DADQDV010000000
VERSION     DADQDV010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 82819)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 82819)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..82819
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.003"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            318..1187
                     /locus_tag="J8S10_000170"
     CDS             318..1187
                     /locus_tag="J8S10_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HAZ9628788.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            1396..2421
                     /locus_tag="J8S10_000171"
     CDS             1396..2421
                     /locus_tag="J8S10_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HAZ9628789.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            2460..3410
                     /gene="manA"
                     /locus_tag="J8S10_000172"
     CDS             2460..3410
                     /gene="manA"
                     /locus_tag="J8S10_000172"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HAZ9628790.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIASEPGK"
     gene            3504..5207
                     /locus_tag="J8S10_000173"
     CDS             3504..5207
                     /locus_tag="J8S10_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAZ9628791.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKTSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            5209..7242
                     /locus_tag="J8S10_000174"
     CDS             5209..7242
                     /locus_tag="J8S10_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAZ9628792.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            7253..7693
                     /locus_tag="J8S10_000175"
     CDS             7253..7693
                     /locus_tag="J8S10_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAZ9628793.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAETIEEVQMIFEHGHI"
     gene            complement(7893..9020)
                     /locus_tag="J8S10_000176"
     CDS             complement(7893..9020)
                     /locus_tag="J8S10_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9628794.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLSLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLLDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(9023..9700)
                     /locus_tag="J8S10_000177"
     CDS             complement(9023..9700)
                     /locus_tag="J8S10_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9628795.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            9964..11730
                     /locus_tag="J8S10_000178"
     CDS             9964..11730
                     /locus_tag="J8S10_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HAZ9628796.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEAFATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            11745..12182
                     /locus_tag="J8S10_000179"
     CDS             11745..12182
                     /locus_tag="J8S10_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAZ9628797.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            12195..13346
                     /locus_tag="J8S10_000180"
     CDS             12195..13346
                     /locus_tag="J8S10_000180"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HAZ9628798.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(13408..14106)
                     /locus_tag="J8S10_000181"
     CDS             complement(13408..14106)
                     /locus_tag="J8S10_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobyric acid synthase"
                     /protein_id="HAZ9628799.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(14099..15451)
                     /locus_tag="J8S10_000182"
     CDS             complement(14099..15451)
                     /locus_tag="J8S10_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HAZ9628800.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(15674..17074)
                     /locus_tag="J8S10_000183"
     CDS             complement(15674..17074)
                     /locus_tag="J8S10_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HAZ9628801.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            17235..17972
                     /locus_tag="J8S10_000184"
     CDS             17235..17972
                     /locus_tag="J8S10_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HAZ9628802.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            18097..18576
                     /locus_tag="J8S10_000185"
     CDS             18097..18576
                     /locus_tag="J8S10_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HAZ9628803.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            18573..19340
                     /locus_tag="J8S10_000186"
     CDS             18573..19340
                     /locus_tag="J8S10_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9628804.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            19570..20139
                     /gene="lepB"
                     /locus_tag="J8S10_000187"
     CDS             19570..20139
                     /gene="lepB"
                     /locus_tag="J8S10_000187"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAZ9628805.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(20243..20845)
                     /locus_tag="J8S10_000188"
     CDS             complement(20243..20845)
                     /locus_tag="J8S10_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAZ9628806.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            20951..21420
                     /locus_tag="J8S10_000189"
                     /pseudo
     CDS             20951..21420
                     /locus_tag="J8S10_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            21526..22110
                     /locus_tag="J8S10_000190"
     CDS             21526..22110
                     /locus_tag="J8S10_000190"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HAZ9628807.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            22113..23186
                     /gene="prfA"
                     /locus_tag="J8S10_000191"
     CDS             22113..23186
                     /gene="prfA"
                     /locus_tag="J8S10_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HAZ9628808.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            23179..24018
                     /gene="prmC"
                     /locus_tag="J8S10_000192"
     CDS             23179..24018
                     /gene="prmC"
                     /locus_tag="J8S10_000192"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HAZ9628809.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            24011..24190
                     /locus_tag="J8S10_000193"
     CDS             24011..24190
                     /locus_tag="J8S10_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9628810.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            24212..25237
                     /locus_tag="J8S10_000194"
     CDS             24212..25237
                     /locus_tag="J8S10_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HAZ9628811.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            25428..26672
                     /locus_tag="J8S10_000195"
     CDS             25428..26672
                     /locus_tag="J8S10_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HAZ9628812.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            26825..27772
                     /locus_tag="J8S10_000196"
     CDS             26825..27772
                     /locus_tag="J8S10_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAZ9628813.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            27906..28535
                     /gene="upp"
                     /locus_tag="J8S10_000197"
     CDS             27906..28535
                     /gene="upp"
                     /locus_tag="J8S10_000197"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HAZ9628814.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(28674..28916)
                     /locus_tag="J8S10_000198"
     CDS             complement(28674..28916)
                     /locus_tag="J8S10_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9628815.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            29037..29109
                     /locus_tag="J8S10_000199"
     tRNA            29037..29109
                     /locus_tag="J8S10_000199"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:29070..29072,aa:Thr,seq:cgt)
     gene            complement(29228..29866)
                     /locus_tag="J8S10_000200"
     CDS             complement(29228..29866)
                     /locus_tag="J8S10_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAZ9628816.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(29989..30621)
                     /locus_tag="J8S10_000201"
     CDS             complement(29989..30621)
                     /locus_tag="J8S10_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HAZ9628817.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            30972..31271
                     /locus_tag="J8S10_000202"
     CDS             30972..31271
                     /locus_tag="J8S10_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HAZ9628818.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
     gene            31766..33931
                     /gene="acm"
                     /locus_tag="J8S10_000203"
     CDS             31766..33931
                     /gene="acm"
                     /locus_tag="J8S10_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HAZ9628819.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(34203..34688)
                     /locus_tag="J8S10_000204"
     CDS             complement(34203..34688)
                     /locus_tag="J8S10_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HAZ9628820.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     gene            35168..35809
                     /locus_tag="J8S10_000205"
     CDS             35168..35809
                     /locus_tag="J8S10_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAZ9628821.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            35828..36463
                     /locus_tag="J8S10_000206"
     CDS             35828..36463
                     /locus_tag="J8S10_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAZ9628822.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            36481..37296
                     /locus_tag="J8S10_000207"
     CDS             36481..37296
                     /locus_tag="J8S10_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HAZ9628823.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            37615..39051
                     /locus_tag="J8S10_000208"
     CDS             37615..39051
                     /locus_tag="J8S10_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAZ9628824.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            39240..41687
                     /locus_tag="J8S10_000209"
     CDS             39240..41687
                     /locus_tag="J8S10_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HAZ9628825.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            41917..42984
                     /gene="rlmN"
                     /locus_tag="J8S10_000210"
     CDS             41917..42984
                     /gene="rlmN"
                     /locus_tag="J8S10_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HAZ9628826.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(43177..44280)
                     /locus_tag="J8S10_000211"
     CDS             complement(43177..44280)
                     /locus_tag="J8S10_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAZ9628827.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            44832..45380
                     /gene="aac(6')"
                     /locus_tag="J8S10_000212"
     CDS             44832..45380
                     /gene="aac(6')"
                     /locus_tag="J8S10_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HAZ9628828.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
     gene            45926..47587
                     /locus_tag="J8S10_000213"
     CDS             45926..47587
                     /locus_tag="J8S10_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HAZ9628829.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(47657..48004)
                     /locus_tag="J8S10_000214"
     CDS             complement(47657..48004)
                     /locus_tag="J8S10_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HAZ9628830.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSTLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            48088..49029
                     /locus_tag="J8S10_000215"
     CDS             48088..49029
                     /locus_tag="J8S10_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9628831.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            49030..50073
                     /locus_tag="J8S10_000216"
     CDS             49030..50073
                     /locus_tag="J8S10_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9628832.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            50079..51149
                     /locus_tag="J8S10_000217"
     CDS             50079..51149
                     /locus_tag="J8S10_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9628833.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            51139..52092
                     /locus_tag="J8S10_000218"
     CDS             51139..52092
                     /locus_tag="J8S10_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAZ9628834.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            52104..53114
                     /locus_tag="J8S10_000219"
     CDS             52104..53114
                     /locus_tag="J8S10_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAZ9628835.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(53399..54220)
                     /locus_tag="J8S10_000220"
     CDS             complement(53399..54220)
                     /locus_tag="J8S10_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HAZ9628836.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(54317..54595)
                     /locus_tag="J8S10_000221"
     CDS             complement(54317..54595)
                     /locus_tag="J8S10_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9628837.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            54863..56872
                     /gene="metG"
                     /locus_tag="J8S10_000222"
     CDS             54863..56872
                     /gene="metG"
                     /locus_tag="J8S10_000222"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HAZ9628838.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(57351..57938)
                     /locus_tag="J8S10_000223"
     CDS             complement(57351..57938)
                     /locus_tag="J8S10_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9628839.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            58113..59435
                     /locus_tag="J8S10_000224"
     CDS             58113..59435
                     /locus_tag="J8S10_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAZ9628840.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            59590..60366
                     /locus_tag="J8S10_000225"
     CDS             59590..60366
                     /locus_tag="J8S10_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HAZ9628841.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            60359..60928
                     /gene="rnmV"
                     /locus_tag="J8S10_000226"
     CDS             60359..60928
                     /gene="rnmV"
                     /locus_tag="J8S10_000226"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HAZ9628842.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            60921..61805
                     /gene="rsmA"
                     /locus_tag="J8S10_000227"
     CDS             60921..61805
                     /gene="rsmA"
                     /locus_tag="J8S10_000227"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HAZ9628843.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            62256..62885
                     /locus_tag="J8S10_000228"
     CDS             62256..62885
                     /locus_tag="J8S10_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9628844.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(63009..64118)
                     /gene="ugpC"
                     /locus_tag="J8S10_000229"
     CDS             complement(63009..64118)
                     /gene="ugpC"
                     /locus_tag="J8S10_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HAZ9628845.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            64327..64749
                     /gene="mgsA"
                     /locus_tag="J8S10_000230"
     CDS             64327..64749
                     /gene="mgsA"
                     /locus_tag="J8S10_000230"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HAZ9628846.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            65072..65608
                     /locus_tag="J8S10_000231"
     CDS             65072..65608
                     /locus_tag="J8S10_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HAZ9628847.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(65648..67411)
                     /locus_tag="J8S10_000232"
     CDS             complement(65648..67411)
                     /locus_tag="J8S10_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9628848.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(67414..69129)
                     /locus_tag="J8S10_000233"
     CDS             complement(67414..69129)
                     /locus_tag="J8S10_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9628849.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            complement(69908..70132)
                     /locus_tag="J8S10_000234"
     CDS             complement(69908..70132)
                     /locus_tag="J8S10_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9628850.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            70332..73100
                     /locus_tag="J8S10_000235"
     CDS             70332..73100
                     /locus_tag="J8S10_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAZ9628851.1"
                     /translation="MLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNTVSH
                     YLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQPKDL
                     FSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLHDLL
                     EDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLDEVH
                     RLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRIPIR
                     IELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGELKNI
                     VKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLMEKQ
                     QPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHELLVY
                     WTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELEQQV
                     SQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIAAHG
                     YATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILVDMG
                     SLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPEWRL
                     LYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNSDPL
                     FSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQRII
                     RNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLIERL
                     IRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSEDTE
                     FLSIEEEF"
     gene            73181..73600
                     /locus_tag="J8S10_000236"
     CDS             73181..73600
                     /locus_tag="J8S10_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HAZ9628852.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            73612..74082
                     /locus_tag="J8S10_000237"
     CDS             73612..74082
                     /locus_tag="J8S10_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAZ9628853.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            74099..74878
                     /locus_tag="J8S10_000238"
     CDS             74099..74878
                     /locus_tag="J8S10_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAZ9628854.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            74865..75686
                     /locus_tag="J8S10_000239"
     CDS             74865..75686
                     /locus_tag="J8S10_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAZ9628855.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            75703..76752
                     /locus_tag="J8S10_000240"
     CDS             75703..76752
                     /locus_tag="J8S10_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAZ9628856.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            76765..77769
                     /locus_tag="J8S10_000241"
     CDS             76765..77769
                     /locus_tag="J8S10_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAZ9628857.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            78402..79421
                     /locus_tag="J8S10_000242"
     CDS             78402..79421
                     /locus_tag="J8S10_000242"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HAZ9628858.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
     gene            79464..80345
                     /gene="galU"
                     /locus_tag="J8S10_000243"
     CDS             79464..80345
                     /gene="galU"
                     /locus_tag="J8S10_000243"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HAZ9628859.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
     gene            80645..81022
                     /locus_tag="J8S10_000244"
     CDS             80645..81022
                     /locus_tag="J8S10_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9628860.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            81628..82242
                     /locus_tag="J8S10_000245"
     CDS             81628..82242
                     /locus_tag="J8S10_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAZ9628861.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
BASE COUNT        27795 a        14320 c        16902 g        23802 t
ORIGIN      
        1 aaatttttct tactactcga aactaagcga ctttttcaca acctcttcct taaacggtgt
       61 tcaaaagctt gcatctgcgg taataagccc aaccaaacga aaaataggag gagctatttt
      121 tgtttggctg ttcttattac ttgatgcaga acagcttttt cacaacctct ttttataaga
      181 gtttttactc attaatttac aaaaaacaag caaaatgcga attttctcac atttttttta
      241 acaaaatcaa agttattgct tgaaagaaga agaatccatc gttaaaataa agcttgacgt
      301 agaggggagc aagaaatatg aaagattttc aattgggggc tgccacctat ttaaaaagtg
      361 tagccattcg ggtgaaagac cgagataaaa tgattgattt ttacaagaac gttgttggct
      421 ttgatttgaa aagagaagaa aacgaattag ccattttagg aacagaagaa gctggaagtg
      481 aaatgttgct gctggaagaa agtcctagag cgaatgatca catgggggtg atcaaaaagc
      541 tgaaccgttt ttcattgatt atccctagca cagaagaaat ggcagatatc ctttgtcgta
      601 tccgtaaaat gaattatcca atcaaagaag ctttagaaga tcatggacgt atggggattt
      661 tgctcgtaga cccagaagag aatgaattgg aaatttacca tgaagagaat aagaacgacc
      721 aaagagaaat tccagaaaca atggatcaag aagcattatt aagaaaatct gaagaaaaat
      781 tcagtaaact atcaacaggt tcttattttg aaaaaatcca tttaaatgtt actaacttaa
      841 caaaagaacg ccaatttctt aatcatgtac ttggtttgaa ggtacataat gaagaagagg
      901 gcatccatgt attgaatgaa ggagatttcc atgttggttt gacagaagct agcggaggcg
      961 caattgattt gcctacagat gaagtgattg gacttgattt tctgaaattc atgatcgata
     1021 ctgaaagcat ggaaggactg attgctcact tgcagcaact atcagttgat ttcttcttag
     1081 acaaaaagca cacagtactc acaatctatg atgctatagg aatcgaatgg tggttcgtca
     1141 gtgagccaaa agaaaagaat aaaactgaca ttcgatgcga cgcttaactt tttctttctt
     1201 aacgattgtc gcatgtctcg tcattttatg aacggtcata ctatcgctta ttctagagat
     1261 agaaagagaa aatagtatac cgggggaaac tgcgcggttt ttcgcgcagt ttttttgtgt
     1321 aaaaaaggtt gattcctcat agattaagct ttaagcttgg actgtaagaa tctgatagaa
     1381 aagcaggaga aaaagatgta tccacacacg aaacagctta ttttgaaaaa gatggaagaa
     1441 ggattttatc caggtgtagc agtcgccttc ataaaagaaa atcaagtaga aacatttaca
     1501 gccggctttg cccaagtcgt tcctgaaaag cagctgatga cagaagatct gttgtttgat
     1561 gcagcctcac tgacgaaagt cgttgcaacc acttcattag ttttacgtct attagaagat
     1621 ggaaagatag aactcgatca accgcttcat aaatatcttc ctgaatttga aaatcagaca
     1681 atcactttgc gtcatttact gacacatact tctgatatca aaacatggat accaaacaga
     1741 gataagctat ctcaggaaga attgatcgcc gcttatttga agctagaacc aggtgagcaa
     1801 ctaggaaaag aagtaaaata tacagatgcc ggtacgattc ttcttgggtt gatgctagag
     1861 gaaatttacc aagaaactgc agtggaaatc tttcaagaac aagtattgga accattagga
     1921 atgatgaaca gcttatttct tccttttcct tccaaaaaaa tcgttcccac agaacaactg
     1981 ccttcgggtg aggttttgcg tggacaaact catgatccga aagcaagagt tttggctgaa
     2041 catgcaggta acgcgggtct ctttattgat ttgaaagaca gcattacttt tgtccaaatg
     2101 tatttgaaca agggaaaaat ccgtaatggt cgttttttag aagaagagac gattgattct
     2161 ttactgcaag atcaaacacc gaaaaaaaat ggctatcgtt ctttaggatg ggacttaaaa
     2221 aaggatgtag aagacggtca tgcgattctt tttcatactg gttatacagg tacgtttttc
     2281 ttgattgata taaaaacaca agaagcgttg atatttttgt caaatcgcgt acatcctgtc
     2341 gatcatcgtg cggagtatct catatgtcga gatgaaattg ttgaaaactt tttgaaagag
     2401 aaagcggtat taccgaaata atgctataat agctatgaaa aatgagagga gtttgaatta
     2461 tgcaggaacc tatgttttta aaaccagttt ttcaagaaaa aatttgggga ggaagtcgtt
     2521 tacgttcagt ctttggtttt gatatcccta acgataaaat cggagaagat tgggcgatca
     2581 gtgcgcatcc tcatggtgtc agtgtagtag aaaatggcga attcaaaggg aaaagattag
     2641 atgaactatg gtcagaacac aaggaattgt ttggccatcc ttcagaacca gtgtttccat
     2701 tattgatcaa gatcttagac gcagaagatg atctatctgt acaagtacat ccagatgatg
     2761 cctatgggat gaaacatgaa ggtgaattag gaaaaactga atgctggtat atcatcgatg
     2821 ctgaacctgg tgcagaaatc atctatggtc atcatgcaaa gacaagagaa gaactagctg
     2881 agatgatcaa agatgggcgc tgggatgacc ttttgaagaa agtaccagtt aaaaaaggtg
     2941 atttctttta tgtaccaagc ggaacgatcc atgctattgg taaaggaatc atgattttag
     3001 aaacacagca aagttctgac acgacttacc gcgtgtatga ctacgacaga aaagatgcgc
     3061 aaggacaaac aagagagctg catatccaac aatcgatcga tgtaacaact gtccctgcga
     3121 aaacaccaga attacaaatc aaagaagtcc gaaaagggaa ttcatcgatc gtcacttatt
     3181 tagaaactga gtttttcaat gtatatgagt gggatattaa aggaatcaca tctttcaaaa
     3241 aacaagcccc ttatacattg atgacggtaa tcgaaggagc aggagacctt gtcgttgacg
     3301 gaaaaacata tccattagaa aaaggaacaa gctgtattat tccaaatggc gtttctgagt
     3361 gggcggtcca aggtgaacta gcaatcattg cgtctgaacc aggcaaatag ttcccagata
     3421 gctgaaagca gcagacggtt tttcgtttgc tgctttttct acataaaatc cgtccatcaa
     3481 taaatagaag tctggtgaaa aagatggaat acaaatggaa agcaaacaac agcagtcgcg
     3541 tgtctatgaa acaactgaga aaagctggac atcacttaaa tgaaatgatc atgccaaatc
     3601 taagtctgtt tatcgcttgg ggaatcttgt cattagcaac aaaaggtgtg tctggcgatt
     3661 tgcacaccac attagaagag gtatgccatt ggatgatcca gctgctttta cccatcttga
     3721 tcagttattc aggcgggaaa tcggtagggg gacaaaaagg ggcagtcgcc ggtgcaattg
     3781 cttctttagg gttgatcgct cgttccaatg ctccacaaat cgtaggagcg atgattatcg
     3841 ggccgcttgc cggcatcgta tatgaacaat ttgtttctag attccatgtg aaattcaagg
     3901 ctggatatga aatgcttgtc agcaacctac tagtaggact gactggtagc gttatttgta
     3961 taattggaat cgtttttatt gaaccagttt taaatagtgt tcacttgttg ctcgcctccg
     4021 ttgtgtcttg gctagtcaca atgaatctgt taccacttgt cagtctgatc ttagaacctc
     4081 taaaagtact atttttcaat aatgcaatca atcatggtgt attgacacct ttaggaatcg
     4141 aattctcaca aacagtcggg tactcttcct tatttttgat ggaggcaaat cctggacctg
     4201 gtttagggat cttactttct atcctttgtt ttgcagaaaa acaggaaaaa gtaaatgcga
     4261 gtggagcatt gatgatccat gcgattggcg ggattcacga aatctatttt ccatttgtct
     4321 tgctgcgacc gtatctattt ttagctgtaa tggctggtgg ggcaagcggc acgttgatat
     4381 ttcaatggtt agatacggga ttagctgcac ctgtatcgcc tgggtcacta ctcgtgattt
     4441 ttgccaatgc gccttatcca caactagctg gggtaagtat agggatagca atcagtacat
     4501 ttgtgacctt catttgtgca gcgatactat tgaaattacc aaataaagaa aaagagaaca
     4561 aaacggtcaa agaaagggga gaaatcttgg aaccatctat cattcattcc gtcatttttg
     4621 cttgcgactc aggtatggga tcaagtgcta tgggagccgc cctgctgaaa aagaaattag
     4681 cagcagaaaa aatcgatctt tctgtcggat acagctctat ctatgaattg aataaccaag
     4741 taaatcagct ggttatcgtg caacatgaac tagcgggtct tgcaagagaa aaagtacctc
     4801 aaagtcaaat ctatgtactg gatcactttt tggaaacaga tatcttgctg tcacgaataa
     4861 aagaagcgat ccaatttcca aagcgggaag aaaaaaaaga gatagcagat atcacagaac
     4921 aaaaaacgtc gcctgctaat attgtatttt tgtataaaaa caacagacgc ggctcacaaa
     4981 ctatgggcat gacgatttta agtcaattag caaaaaaagc gaaaaaacag tttgttatct
     5041 caaaagaatc aatagaaaaa atcaaaatcc aagaagaaac gatttatatc gcacaaagag
     5101 aactagctgt aactgaacag ctagaagaaa agatccctcg gctagttcta gttgaacatt
     5161 gggtagctac gaatgaatac gaaaaactcg tgaagggaga aatataagat gtatttatcg
     5221 cccagagaaa aacaattatt agcagaattt ctcagtagcc cgtcacctgt atctatccaa
     5281 aaaatgatga atttattgaa ggtcagtaaa cggactattt accgcgaatt agataatctt
     5341 gaagtctcat tgaaatcggt aaatgcttct ttgaaaaaag cagctagagg ctcatttgtc
     5401 attgaggcat cagaagaagt attagagcaa ttaaaagaaa atacagatgg gaaaagtaat
     5461 gacttatcca ctgctaaacg acaacacgcg attttagccg agttgttact gacgacagag
     5521 ccgttgagtc ttgctcattt catggaatca tatcgcatca gtaataccac tttttatgca
     5581 gatatcaaac agttggaaga aagtattcgc caactgcctt tggaaatcat tcggaaccag
     5641 ggatacgaga tcgaaggacc ggaaaaatac cgccggcttc tgacagcgaa tgtattagaa
     5701 ttagaaatca atgaatatga actttttcat agtatttctt tcgatgcatc actgaattat
     5761 ttttttcgat tcgttgatcc gcaacatcta tctcttgcac gcaaagtaat cggggaagaa
     5821 ttgatccaaa aaaagaccaa tctaagtgat agaaagcttg aacatttggt tttgatgctg
     5881 acattgacga tggagcgtgt gacgaaaaat catttactga caaatgagac atataatagt
     5941 ctggcaaaca aagaattact acagacagct aaacgattgt tttcacggat cgcttctgag
     6001 acaaaacaac tttatccagt aaatgagatc gtcttttttg caggattatt aaatgacttc
     6061 acgaactcat ttgatcagaa tttctttgaa gagacgttcg atacacagct tgcttattta
     6121 gtaaaacaac tgattcaaga agtaagtgaa gagacgaatg tccattttta tgaagatgaa
     6181 actttgtaca aaatgctgtt gactcattta tctggtgtgt tttcaagagc cgttttacaa
     6241 gaagagacac tgaccaatcc gattttagaa aaaatcatgg ttcaatacga ggaagttgcg
     6301 aatgcaatcc gtaaagcagt agagcggatt tttcaagaaa aaaaattatc cgaagaagag
     6361 atcgcttata tggtccttca ttttgcgaat tcattggaac gaagtccgaa agaaagcaat
     6421 atcagtattg caggattttc gccaagtgga ttagcttcta ctagcatgtt ggaactacga
     6481 ttgaaaaggt attttccctt catccaacaa attcatttct atcggattgc tgatttaaaa
     6541 aaaatcgatt tacaagaaga atatgatgtt gttatttcta catctatttt accaggatac
     6601 ggtggaaaat atattttagt ctccccgcta ctgctagaag atgaagtcaa gcagctaaaa
     6661 gaagcttttt cgcatattga gaagaaaaaa aggcaaaaaa ttacgtataa cagcaataac
     6721 gagtggatga tagaagatac ttatgaggaa acaatgcatt tcatggatca aatcaatcaa
     6781 ttactcggtc gtttttttat ccaagaactg gataatcctg agacgatttc cgaaacgatt
     6841 cgcagcttat ttccttattt tcctgaagga ctagtaacgg atgaagaggt ggttcatcgc
     6901 cggctgctta agcgatatga acaagcacct atcggtattc ctcatacaaa tatggggtta
     6961 ttccatacat ccagctcatt gatttctaaa ccgatctttt gtattttcaa tttgaaacat
     7021 ccgttgacca ttgaagggat ggatagacag ccagtcgatt tgtcccgtat gttagttatg
     7081 ctggcgcctt cgccaatcca agaaaaagac gggattcttt taggaaagat cagtggagca
     7141 atcatcatga atgacttgaa caccgagatc ttccgctcag gaaataaaga aatcgtttat
     7201 cagttgttag cgaaaatcct gattgaagaa ataaagaaat gaaggtgaaa agatgataca
     7261 gctaccagca gaaaaaatat tgctcgatca atcctatcaa aattggaaag aagcgttgac
     7321 cgagatcggc cagtggatga cccaacaagg gggaatcaaa ccggcatata tccaatcaat
     7381 gatcgaaaga caagaaaaag cgagtgtcta tatcgggaat ttcgtagcct tgccacatgg
     7441 gactgacaaa gatgaagaag tagtagaaga aggaatctat ttagtccaag tgcctgatgg
     7501 tgtggacttt ggaacaaaag aggaaccaaa aatcgcgaca ctcttatttg tagtggcttt
     7561 aaaaaaagaa catcagttag cggtgctcca agatttagcc tttttctgtt cagacatcga
     7621 ccaagtaatg gcgctcagtg atgcggaaac cattgaagaa gtccaaatga tttttgaaca
     7681 tggacatata taaccaatgt tcacagtaaa aaaagctgcc ttgcatcaag taataacttc
     7741 aaccaagata aaaataagag gagctatttt tgttgggagg ttcttattac tgcggatgca
     7801 agcttttgaa aactatttat tctagaaaac cgtttatttg aaatagggga cggtgacaag
     7861 gtttttgtca ccgcccctat tatttttgtg ttttaatagc tcttttttat atagatagtg
     7921 cccataccta tgaataataa aacgatactc catataccaa gtgtcaagat accattcatg
     7981 aaagtaacct gttctgaagc tagtggcgag aaaatatctc ctcctatgat cacattttga
     8041 aaatcaacat aagaagttgg caagtaatga ctgattgatt ctatccatcc aatcgaagaa
     8101 aacaagcgat actctgctaa gaaaagacaa agaagtgtac ctaaaagatt gactagagaa
     8161 tgttcaaata aagcagatag aagaaaactg attgtactta aaaagagcac ccacaacaac
     8221 aggaacagaa agctctggaa aagatactca tacatcggca ggattcgtat ctcctgacca
     8281 atgatcgttc ctacaggata acggaagtct cccaaaccat ttttgattat tactagtata
     8341 gagacgatca aaaatggcat cacgagactt agcatagctg caccataata aatggtaaaa
     8401 cggatgctat gtttctttac catactatcc agtaatagat tgactagaga gattacctgc
     8461 tttctttttt cataagagat gatggaagaa agaaacaagg cggttataca taaaatcaaa
     8521 aaactagaaa tcattcctga aaaaatattt tcgtagtaat ttgctaaaga gagatgcgct
     8581 ggcaagtcaa aaatagaata tctttggatc tgatgttctt tcatataacg gagcaactcg
     8641 acacgttttt gttgttcaat gattggaatt ccttgtcttt gaccagaaat cagtcgatcc
     8701 agtatatctt tttcataatg ataagttgct tcgaccattt gctggacatt ccctgtgttt
     8761 tttgcatgta agattgcttc gatcagtttg ttgcttttct ctaaactttc cacaaattct
     8821 ttctcattct catcttcttt caacgtttca atcaaacgtt gcatctcttc atagttatga
     8881 ttcagttcat cgaattctgt ataagcaagt ttatgatcaa aaaaaagtgg gaatgcaaag
     8941 agcacgacca acaatagagg aaataaaaag tttactttgt tttttagtaa gagattgcgt
     9001 tcaaatgtaa gtaaagacat agttacacct catataattt acgataaata gctaaaatct
     9061 cttccatatt tgaggattct gtgacgattt ctccattttt tagaaaacat gctttagaac
     9121 aaatcgattg gatattcgcg atagcgtggg aagaaagaag aatcgtcttc ccctctttct
     9181 gccattgtct gatgaggcta ttcaagatat caatacttcc tgggtctaat ccgttcaacg
     9241 gttcatcgaa taacatgaca gatgaatcac tgatcaagta agcagcaagc aagacatgtt
     9301 gtttcattcc tagagacatt tttccaatcg gcaaagtaag gtactcagtc atcttcaatc
     9361 gttggaaaac agtttggcat tctactttgc tctgccaata gtatttgatc aaagtcaaat
     9421 aatcaacagc cgatagatag tcggataact gattcgttga ttctagaaaa aagaaagacc
     9481 ggcgataatc tgtataagca gtaggagaga tgttgtgaag ggacaattga tcataagttg
     9541 ttggcagcag ttgggcaatg ccattcagca aagttgtttt gccaaatccg ttcggggcaa
     9601 tcaaagcagc tacttctcct gattctacta aaagattcaa ttgtcgaatc acacgttttt
     9661 taccacgttt catgttcatg tttttgatca gtaatgtcat agataggcct ccaatataaa
     9721 atttaataac ataatagaat ggaaaacatc taaattaaat gctaacaaaa gttattgttt
     9781 gcatattata aaaaaattaa aataacagtt ttatttaaaa ttgaagtttt ctgataccga
     9841 aatcttttta ttttgctgac atactcaaac ctttggcaca aagtttcgtg ccaaagtacg
     9901 actatttctc tttttagtaa gcggatacaa ttagagtatc aaaaggagag agggagagac
     9961 aaaatggaac ggacgattcc caaaaacaac atttcgctaa aagcgagggt acaaaaatta
    10021 ggcagtactt tatcaagcat ggtcatgcca aatattggag cactgattgc ctggggtgta
    10081 ttaacggctc tatttatccc agatggttat ttaccaaatg aggctttcgc taccatggta
    10141 agcccaatgc taacttatct gattccttta ttgatcggtt atactggcgg aaaagtaatt
    10201 gctggtgacc gcggatcagt tgttggggca attgcaacga tgggtgtgat tgtcggaaca
    10261 gatattccaa tgatgctagg cgcgatgatc atgggacctc ttggtggata tgccatcaag
    10321 aaatttgatc agctattcca aaaacggatc aaatccggtt ttgaaatgct agtcaataat
    10381 ttttcagcag gtcttatcgg ttttggatta gcgttattag gtttttctgc gattggtcca
    10441 gttgtcgatg cattgactca agcaatggca aaaggtgtag agatcatttt atctgcccat
    10501 ttgattccat tgacaagtat ttttattgaa ccagcaaaaa tcttattttt gaataatgca
    10561 atcaatcatg ggattttgac accattggga actgaacaag tagcagaggc tggaaaatct
    10621 attctattct tgcttgaagc aaatcctggt ccaggacttg gcgtattact tgcttttact
    10681 ttgtttggca aaggagcagc aaaatcttca gcaccaggag ccatgatcat tcacttttta
    10741 ggcgggatcc atgaaatcta ttttccttac gttatgatga aaccgttatt attcttatca
    10801 gttataggcg gaggaatgtc aggaagtttc attttccaat tgatggatgc tggactaaga
    10861 gcgccagctt ctccagggtc gatcattgcg attctagcga tgacaccgtt caattcttac
    10921 cttcctgtta ttttgggcgt gattgttgcc gcagctgttt cgtttggtat ttctgcagta
    10981 attttgaaag cggatgcgaa agatacaaat gaagacttcg aaaaatctgt tcaagagaca
    11041 aaggcagcta agcaagcttc caaaggtgcc caaggtattc ctcaaggagc tacattctct
    11101 ggcgtacaaa aaatcatttt tgcttgtgat gcaggaatgg gatcaagtgc gatgggcgct
    11161 tcgatcttga gaaaaaaagt acaggaagca gacttgcctc aaacggtgac caatcaagca
    11221 atcagccaac tgacagatga ctcgaataca ttgatcgtta ctcaggtcga actacaagaa
    11281 agagcaaaac aaaaagcacc gagcgcgcgt tttgtctcag tagaaaactt tttgaattca
    11341 cctcgatatg atgaaatcat tcaagaatta agcagcaagc agaaaacatc agtttctgaa
    11401 attgagaatg agccagcaga agagtttctt tcagcaaaca tcaaacaaat caaagagatt
    11461 ctacttgtcc acgatgatcg ttccggatca gcaacaatgg ggatgaccgt gctcaaagat
    11521 atattagaca agaaccattt aactatcccg ttaagaaaag tcaatatcca agatttaaaa
    11581 gatgaacctg attcactgat cgtagccaaa gaaagtttag cggaaaaagt acagatggct
    11641 gcacctcaat ccattcattt atcagtcaac agcatggtca atccgcaaaa atacgaatcg
    11701 attgcacaat atttgaaaca gacagcttaa gggaggaaaa cagcatgcaa agtttgccat
    11761 tcgacatgat cgagctcaat cgatctttta aaaccaaaga agaagcgatc cgctattgcg
    11821 gtcagatgct tgtagaagca gggtgcgttg atgaggaata tatcgatgcc atggtagata
    11881 gagacaaaat gttatctgtt tatatgggga attttatcgc gattcctcat ggaacagatg
    11941 aagcaaaaaa atatgtgaaa aaatccggca tctgtgtcgt tcaagtacca gatggtgtag
    12001 attttggtac cgaagaagaa gaaaagattg cgactgtttt gttcggtatt gcaggagtcg
    12061 gagatgagca tttgcaactt gtacagcaaa tcgcacttta ttgcagtgat atggacaatg
    12121 ttgtccagct agcagacgcg ctcagcaaag aagaagtaac ggaaaatcta gcaattgctt
    12181 aaggagagag aaaaatgaga gcagtacatt ttggtgcagg aaatatcggt cgaggattta
    12241 ttggagaggt tttggcagct aatggatttg agattacttt cgtagatgtg aatcacacga
    12301 tcattgatgc tttaaatgaa agaaaagaat acgaaatcga attagcagat gaatcaaaag
    12361 aaaaaatcac tgtaaaaaat gtcaaaggaa tcaacaatca aacaaatcca gaaaaagtaa
    12421 tccaagaaat cgctgaagca gatttagtta ctaccgccat tggcccgaat atcttacctt
    12481 ttattgctga gttgattgca aaaggtatcc aagaaagaga aaaggaagga agcacaacat
    12541 ctttagatat cattgcctgt gaaaatatga ttggcggttc agcatttcta gaaaaagaag
    12601 tgtataaata tcttccggaa acatcattta ctgacaaata tatcggcttt ccaaatgcag
    12661 cagtcgatcg aatcgtccca ttacaacacc atgaagatcc tttattcgtc caagtggaac
    12721 ctttcaaaga atgggtcatt gacgatagcc aaagaaaaaa taaaaaaatc caattaaaag
    12781 gggttttata tgtagatgat ctagaaccat atatcgaacg caaactattt agtgtcaata
    12841 ctggtcatgc gactgtcgct tatacaggtg ccttgttagg ttaccagacc attgatgaag
    12901 caatgcaaga tgcgttagtt gtggcacaat taaaatcagt tttgcaggaa acaggaagtt
    12961 tgctgattgc caaatggggg tttgatgcag agcagcatca tgcgtatatt gaaaaaatca
    13021 ttcatcgctt ccaaaacaaa aatatctctg atgcgatcac acgtgtcgct cggacaccat
    13081 tacgtaagtt aggttatcaa gaaagattta cacgtccagt gagagaacta caagaacata
    13141 acttgacttg cccacatttg acggcaacaa tggggattat ttttaattac tatgatcctg
    13201 aagatgaaca aagccgtcaa ttgcatgaaa tgaagatcca tgaaaacttg gaacaattga
    13261 ttcaagaagt cacaggaatc aatgatccga aaacaatcgg gaatatcaag caaaacgtga
    13321 accgttatgc caagcaagtc gcttaaaata ggatacgaaa aaggggaatg tgacgaaatt
    13381 tttgtcacat tccccttttt cgaataacta ggctgtttgt ccttcaagat agggcagatc
    13441 caattcttta ccgtaacgtt gttctaaagc taggcggatc aaacgagctg ccaggttctc
    13501 atttcttgca aggataggtc catggaaata agaaccgaag acatttcggt aaatgacacc
    13561 ttcagattgg tcttcaccat tatttccttg accttgtacc actttcccca aaggtcgttc
    13621 accttcacct aagaaagtcc gaccattgtg gttttcaaat ccataataag tttcattgaa
    13681 ttcttcgtta tggataacga tatcaccgat aaaccggtta ttttcctgac ttaacgtgta
    13741 gtgatccagt gcactgattc cttggatctt ttctccatta gctcccatgt agtagtgacc
    13801 tagcaattgg tagccaccac aaatggctaa catgacgcca tcattttcga tatagttgat
    13861 caaagaatct ttctttttct ggatgtcttt tgaaatgatt aattgctcaa agtcttgacc
    13921 accgccaaag aaaaccaagt catatttatc agcatcaaaa ggttcatgta tactaacgat
    13981 ctccgtatgg caagaaaccc ccattttttc tgctatatat ttcaacatca aaaggtttcc
    14041 gttatcacca tatgtgttca tcaaatttcc ataaaggtgg gcgatattga gttcataatt
    14101 agccacggtt cattcctcct ttgataaatc cttgagcagc tagttcttta cgaagctgca
    14161 atacagcagt gtaagtagct aaaatataga catgctcagt tggcaattct ttgatttttt
    14221 cgattacttc tggtaattct tttgtttctg tcaatttatt ttctggaatc ccggcaactt
    14281 ttagacgtaa agtcatatct gtatgacggt ctcctccaga aataacagct gggatatcca
    14341 tatcggcaaa gttttcaaaa ttaccatccc aaatccagct gacatcgatt ccgtctgcgt
    14401 aattggcatt taataaagcc actaaagaaa atggataagg agctagacca atcatatcga
    14461 ttacttgatt gatacctaca ggatttttga caagtactaa tgtacatttt ttcccattga
    14521 tattgatgac ttcttgtcgg ccgaatactt tctcgtcata tcctaaacct tgtttgattt
    14581 tatcaggatc gacattgaag tactctgcca ctgcagtagc tgctaaagca ttgtagacat
    14641 tatacatacc gccaacttcg attccgtatt catgaccatc gatcacgaaa tctgctgaca
    14701 cattgtccat ccgtaccata tcagttaatc gataatccaa ttcaggacgt ttgaagtcac
    14761 aatttggaca gtaatatttc cctaagtttg cataagtgat cattttataa tgcaagatgt
    14821 gatgacaatt tggacataag acaccgtctg tattgtaatg agccatttgt tcacgatctt
    14881 cttcatggtc aaagccataa tattttctag gattgactgt ttcgatagaa ttgaagattg
    14941 gtgaatcacc gttactgata atcgttgcat ttggtgactt tgcggcaccg tctacaatca
    15001 ttttataggt cgtatagatt tctccatacc gatccatttg atcacggaaa atatttgtaa
    15061 ataagaacag ttctggtttc atatattctg tgactttgct caaacttgct tcatctattt
    15121 ctaggacagc aaactttttc tgtccttttt ttggttttgc ctgcaagaaa gtcgatacaa
    15181 ttccctgtac catattcgca ccagtagggt tggttagaac ttcatcgaat tgctggcgca
    15241 aaatattgac tgttaaagcg gtagtcaatg ttttaccgtt tgttccggtg acaacgacga
    15301 cttggtagtc ttttgccaaa ctatctagta tatgtggatc gactttcagc gctagtttac
    15361 ctggtaaact tgatccgcct ttaaaaaaag tttttaatgc ccattgcgac gtttttccaa
    15421 ctgcaatcgc aaaatgactg cgtattccca ttatgtaacc tccaaaaacg atttgctgac
    15481 gaataaattc aactaatcat accatatgtt gaaaaaaagg ttaaattgct tttcttattc
    15541 ttaagaaaag gttacggctg aaagtgcatg aaatcggaca aaatcgcatg atttaacaaa
    15601 aaaacagctt gaaacaaaat gattgtttca agctgctgtg attttattat tccctcttac
    15661 ctatattccc attttaaccg ataataattt tctcgcttgg atattcatag cctagatctc
    15721 gtgtttcttt tggcacgaat aacatcaatg tatatagcat tccgatccgc ccaataaaca
    15781 tcagtgtagc aatcgtgatt ttgcccacaa cagacaagtc tccggtaatc cctaaagata
    15841 aaccagttgt tccaaacgca gaagttactt cgatgatgat cgagatcagc gtttgttctt
    15901 ctgtagcaga taaaaaaacg atacaaaaga aacacatacc aagagaaagc ataaagacaa
    15961 cgactgattt tcgcacatca tcttgatcga ttctccgtcc aaaaatattg atgttatctt
    16021 cacttttgag gaaggaatat agatacaaac cgatgattgc tacagtagtt gttcgaatcc
    16081 cgccgcctac agaactagga ctgcatccga taaacatcag taaagaaaaa atgatcagtg
    16141 ttgtgatttg aaaatcaccc aaatcgtgaa tctgcagacc agcattacga gtcgtaatcg
    16201 aataaaacat cgaattgatc catttgacac tcatattgga atcttggaat aaatggtcct
    16261 tttccaatag ataaatcaag acagttcccg aaacaaacaa gataacaaaa gctaacacag
    16321 ctaatttggt aaacaaggaa aaacgaaacg gaagcttcgc attggaacgt ttgtataata
    16381 gccattcccg gcactccatc aatacaggaa aaccaattcc tccgacaaaa atcaaaaaca
    16441 tgatcaggat caagaaaaaa tagtcatgtg caaagggctt gatggaatcc ccagtgacgt
    16501 caaacccaga gttcgtgaca gccgatatcg cctgataaaa accgtaaaaa acggcatcac
    16561 gccaacgatc aaaatagcct ctgtaataaa aataaataga aaagaatgtc ccaaaaagta
    16621 attgaaacca gattaaaata gcaaaagtga tccgaatcag tcggacgata ccagacaaac
    16681 gcggttgatt catatccgtc atgatcagct gtcgctgttt cagtgtgatc cgtcgtttag
    16741 aaaaaatgac aaaagcagta gaaatcatca tgatccccaa accaccaact tgaaataata
    16801 tttccagcag tataataccg ttatcattga acacagaatt gatatcaaaa gtcgatagtc
    16861 cagtcacact cactgtactg attgccatga acagcatgtc cacaaaagaa acatggctat
    16921 ctggttcgcg aaaaatcggc atataaaata gaacgagtga taagaccgtc atcaatatat
    16981 aataaaaaac gatgatttgg atcgatgaga aatgattggc agcaaacttc tgtcctcgcc
    17041 gctgcagcct tcgaaagaat aaatcaacat gcacagtact atcctcctga caatagtcgt
    17101 ttctaccagt atacaagggg aattaggaat actcaaagaa attatcaaac agataacaat
    17161 acagctttcg attaaaatag aaatggctta taataaggaa aatcctagaa aaaagaagga
    17221 ggaggaataa caaattgatt aatgctcaac aaatcgtaga aaaaatgaaa aatcaaaaaa
    17281 taaattatga tacagttctg aaaaaaatga tcatgcaatg ggagaaagaa gaagtaaagc
    17341 ctaagatatt aatacataca tgctgtgctc cttgcagtac gcacacattg gaattcatgt
    17401 ctcaatatgc agagatcacg ttattttttt caaattcgaa tattcatcct aaaagtgagt
    17461 atttgcgaag attacatgaa caaaaacgat ttgtagacca atttaatgag aaaactgacc
    17521 atcatgttgc gctaatcgtt gatgaatacc gtccaaatga attcaccaaa atggttttaa
    17581 caaaccatct tgaaaacgaa aaagaaggtg gtgctcgctg cagtgcatgc ttcaatatgc
    17641 gattagatct tgttgcgcaa aaagcgcaag aactaggata cgattacttt ggaagtgccc
    17701 tgaccatctc gccaaagaaa aatgcagctt tgatcaatca gatcggaatg gatatccaaa
    17761 agatttacgg gacacaatac ttgccaagtg atttcaagaa aaacaaaggc tatgaacgct
    17821 ctttgcaaat gtgcaaagag tatgatattt atcgccaatg ttattgtggt tgcgtgttcg
    17881 ctgccaagca gcaaggatgc gatctgaaag aaatcaatcg ggaagcaaaa gcttacttaa
    17941 aaacatcaac cgtagttttt gaggaaaatt aaagaaatct ttcggaaaaa cgtaagaaaa
    18001 aaataaagaa tttatggtag aaataaggta gactgtataa tttgtccgta gtaaagtaag
    18061 gaaacaagaa taaatttcaa tgaaggaaga gataagatgc gaaaagtagc acctattttg
    18121 aagccaatcg ctgtattaac aatctcgacg attgtcgcga ctactacagg tattgtgaat
    18181 agttccagct accgtgcacc aagttcaagt tctagtactg tagaagaaac aacaccaact
    18241 acttcagtct cgacatctga accaacaaca acggaaagtt tgaatgaaac cactacgaca
    18301 agtacatggg acgatacaac aactagttcg tcgtatgatg agacatatac aactgacagc
    18361 tcaagcgaaa caagtaatac ggtaccagat ggcactccat cggattcaac caatccaagt
    18421 acaagtccgg atacaagtgc tagctccgaa acgataccaa gcagtacgac tgtagatgat
    18481 aacacgcaaa atgatgatgc agcacgtaca gcacagcaaa accaagattc aggaaatacc
    18541 caaacgtata accagcaagc aggtgattct caatgacatt tttactagac cttatcaacg
    18601 gggtgcataa attccttggc tatttagaca tcagtcctaa atatcttaac cgtggatata
    18661 cgattttaag tgtgattccc acgctttatt tattgagaat tgtttatgga ctttggcaaa
    18721 accaaaacta tcttcaattt ttcttatatg gacttgcatt tctagtgctt gtttatttta
    18781 ctgttttaaa tgtattttat tactttttag ataaaaacac gaaagccgat gtcactcagc
    18841 tttttgtgaa gtatttacct gatgaagcgt tcaacatcca gacagaagaa tcgatagata
    18901 atggaaattc gatcgataaa gtgaatacac aagaggtcat ggtttcttat gacgaagatt
    18961 atcaattgaa attagccgag aatatgcggt atttgattgg aaatggtgag atcaaaacaa
    19021 atgaactcgg tcgcatggat ggatttctgg tcgatagaaa tacattgtat ccttattact
    19081 atgtcaagaa aacaggagag aaagagtatg ttctaaatat tggacgaagc tactcggaca
    19141 tggaaaaagt agggaccatt cgacttgact caacagaaga cacattggaa cctgtcggat
    19201 tgttcatcgt cggcggtgat tttgtcaaag acgggttacg ctatcatgag ccttatcgtc
    19261 tgaaattgat tgcaaaaaag gcacagtcgc aggaagaacc agtggtttat agtcgtagcc
    19321 aaagaagaag acattcataa tgtgatgaaa cgccgtgtat cagtggttgc gataaaaacg
    19381 tttattcgga ataaggggga tgtgacacgt cttttgtcac gttccttttt tatataacga
    19441 gaaagataag acgaacacat cacttattct ttcctttcat ttataaacat tgtagaataa
    19501 agaaagtaca acgaagtatt gtgaaaaaac gtaataaata acgaggaaaa tacaagtagg
    19561 aggtaagctg tgaaagaatt tttgaaaaat tgggggattt tgatccttgt attagcggct
    19621 attttattag ctagagtgta cgtgtttaca ccagttactg taaacgggca ttcgatggac
    19681 cctacattaa gtgatggaca acgattgatt tcatctaaga tctcaaacta tgaacgaatg
    19741 gatattatta ctacaaagga accgggggat gaagaacgga tgattgttaa acggatcatc
    19801 ggtatgcctg gagatacagt caagatggaa aatgaccagt tgaccattaa tggcaaaaag
    19861 tatgatgaac cttatctgga tgagttcaaa aaagaatttt cagaagataa gttacaagga
    19921 gaatatgctt atagctcagg attccaagca caagcagaaa gttcatccac ctttacgagt
    19981 gactttgaat atactgtgcc aaaaggaaag tatcttgttc taggcgataa ccgcttgatt
    20041 tcaaaagaca gccgaatgtt tgggttagtc gacaaagata tgatccaagg aaaagttgtt
    20101 ttccgttatt ggcctctttc agaaattaaa atcatgtgat gaaaaaataa aaagaagctg
    20161 tgacatgttt tttgtcacag cttctttttc cgaaaattcc ttcttatttc ttggagttgc
    20221 tcactttttt tgcaatctca ttttaagctt tttggctgat ggataagaaa agcgaagcgt
    20281 ttttgttcat aaatagcttt tccccacgat ggaaggtatg actagtagca gagacaaagc
    20341 ccgttttttc caatcgatta ttcaattctt cttggctaaa gccattatgg actttcggat
    20401 gactaatttg ttcattcttg tcaaagtcta cgatgatcaa ttgaccgcca ggagctaaaa
    20461 tttcataaag ttttgtaaga atattctccg tatcaggaat gtgtaaaagt acaagtgata
    20521 gaaggatgag attagcttgg acagcaggaa attcgacaga agcatcagcg tggatcgttc
    20581 ggacattttt cagatctgct gcttggatct tttcttctgc cattttcagc atagtttctg
    20641 aagcatcggc aatgatcagt tctttgaatc tttccgcaag cggtaaacta acaagcccag
    20701 ttccgcctcc gtaatccagc aggacttttt ggtggctgtc gcgcggtaga taagtagtta
    20761 gttcttcgcg aataatcttg gctaatgctt gacggtcagg ggaatcataa tggttagcga
    20821 tggaatcaaa aatatttttt gtcatcaaat agctccttac gtaaaacttt gaaattttaa
    20881 cttattatag cacgtgaaaa gaaagaaagc atgctatact caattcaaaa agggagaatc
    20941 tagaaagaat atgccgatat cgtttgtaaa agatagagag gaaaaaggaa agtgtgtccg
    21001 agaaatatta ctagacttgc ctgagtggtt tgggcttcct gaatcaacgg aaaaatatat
    21061 cgaggaatca agtaaactac ctttatggtg tgaaaaaaga aaagaagaat atttaggctt
    21121 tatcactctt tcacagacaa gtgaagatac tgccgaaatc tattctattg tatgggaata
    21181 aaaaaagact atcatcacca aggattagga acaaaacttt ttaaagaagc agaaggttac
    21241 gcagcaaaac attacaaata tttgcaagtg aagactgtag acgaggggca ctactctata
    21301 tatgatcaaa ctatttgttt ctacgaatca ttaggatttt caaggttgga agtttttcca
    21361 aatttatggg atgaatggaa cccatgttta gttcttgtca aaaaattgga acaaaagtga
    21421 gcaatagatt taatactaat ctgtgcttga tgaaaattct cactgtaaaa aatgctgaaa
    21481 atcaagtata ataccatagg aacaaactgg aaggtgaaaa agagcatggc acaactattt
    21541 tttaagtatg gcgcaatgaa tagcggcaag acgatcgaga tcctaaaagt cgcacataat
    21601 tatgaagaac aaaataagcc agttgtctta atgacaagcg gtattgatac aagagatggt
    21661 ttaggcgttg tttcaagccg aatcggactg aaacgtaatg cgatgccgat atttgaagaa
    21721 acagacgtat ttgacgtaat tcagaaaatg gaaagcaaac cctattgtgt gctgatcgat
    21781 gaagcgcaat tcttaaaaaa gaaacatgtc attgctttta cgagaattgt ggacgaattg
    21841 gatattccgg ttatggcatt tggtttgaaa aatgattttc gaaacgagtt atttgaagga
    21901 tcaaaatatt tattgcttta tgcagacaaa atcgaagaaa tgaaaacaat ctgttggttc
    21961 tgccacaaaa aagcaatcat gaatttacat tatattgatg gaaaccctgt ttatgaaggc
    22021 gatcaagtgc aaattggcgg aaatgaagct tattaccccg tttgtcgaaa acattacttt
    22081 cacccatcaa tgattacaga aggagaataa gcatgtacga tcaattacaa gcaattgaag
    22141 accgttatga agagcttgga gaacttttaa gtgacccaga agtgatttct gatacaaagc
    22201 gttttatgca gctttcaaaa gaagaagcaa acacgcgcga aacagtcgaa gtttatcgtc
    22261 gttataaaga agtagtacaa ggaatcaccg atacagaaga actgcttggt gaaaaactgg
    22321 atgatgaaat ggctgaacta gcaaaagaag aattatctga attaaaaaaa gaaaaagaag
    22381 tcttagaaga aaaaatcaag atcttgcttt taccaaaaga tccaaatgac gataaaaata
    22441 tcatcatgga aatccgtgga gcagcaggcg gagacgaagc agcattattc gctggcgatc
    22501 ttttcaatat gtaccaaaag tatgctgaag cacaaggctg gaaaacagaa gtgatggaag
    22561 ctaacgttac cggaatcggt ggatataaag aagtgatcat gatgatcacc ggagacaacg
    22621 tatattcgaa attaaaatat gaaagtggtg cgcaccgcgt ccagcgtgtt ccttcaactg
    22681 aatcgcaagg gcgtatccat acttccaccg caacagttgt cgtgatgcca gaagctgaag
    22741 aagtagagat cgatattgaa gacaaagata tccgtacaga tatctatcat gcttcaggtg
    22801 ctggcggaca gcacgtcaat aaaacagcat ctgctgtacg tttgactcac ttaccaacag
    22861 ggatcgttgt tgctatgcaa gatgaacgtt ctcaaatcaa gaaccgtgaa aaagcaatga
    22921 aaatcttgcg tgctcgtgtg tacgataaga tccagcaaga agcacaaagc gagtatgatg
    22981 ccaatcgaaa atcagcagtc ggaactgggg atcgttcaga acggatccgg acgtataatt
    23041 tcccgcaaaa tcgtgtgact gatcatcgta tcggattaac tatccaaaaa ttagatcaga
    23101 ttttagcagg gaaattagat gagatcgttg atgcattgat catgtatgat caaacatcaa
    23161 aactggaagc tatgcaaaat gggtaaaatg acctatcgag aagtcctgtc acgggcttct
    23221 tcttttttag aggatcatgg gaaagaagca tatagtatcc aatttttatt tttggaacga
    23281 aaacaatgga aaaaacttga ttggctcctt catatgaacg aagagatttc agaagaagaa
    23341 cagcggttga tcgaaaccga tctgcgactt ctgcttgcag atcatccacc tcagtatttg
    23401 ctaggatatg cagattttta tgatcatcgg ttaaaggtaa ctgaagcaac actgatccct
    23461 cgaccagaaa cagaggagtt agtcgaatgg tgtttagacg agacgcctgg tgtaccgtta
    23521 gaagtgatag atattgggac agggactgga gcaattgcta ttagtttgaa agcagcaaga
    23581 aaaaattggc atatatctgc tgtggatctt tcagaagaag cattagaagt agcgaaagaa
    23641 aatgctcaga aagaaggaac gaaaatcagt ttttatcatg gagatacatt aggaccagta
    23701 atggatcagc aatttgatgt gattatttct aatccgccgt acatcagtcg gaatgaatgg
    23761 gaactgatgg atgaaagtgt ccggtcattc gaacctaaaa tggccctttt tgctgagaac
    23821 gatggattag ctatttatga aaaaatagca gttgaagcac caagcgtact aaaatcaaat
    23881 ggaaagattt ttttagaaat cggatttcgc caaggtgaag cagtaaaaaa aatatttcag
    23941 caagcatttc cagataaaaa agtggcgata aaaaaggatc tttttggcaa tgaacgaatg
    24001 atccaagttt atggttgaag ttgtggatga aaaatttttt atttgttttt ttattataaa
    24061 aaaacactta tttgacaagg atgtaaacga ctttttggtt tatcaacaag tttatccact
    24121 attgacaaat agattatcca caaacagtgg aaaacttgag gataaactca gacaaaataa
    24181 gaatgtatga aaaaggggtt gtggataaac tgtggaaacg aaacgatatg atgaaacaga
    24241 attgcaagag gcagccgaag cactgaaaga aggagaactt gttgcttttc ctaccgaaac
    24301 agtatacgga ttgggcgcca acgctctttt accaaacgct gtcaagaaag tgttttctgt
    24361 aaaagggaga ccgcaagata atccattaat cgtccatgtc gcctcttttg aacaagtaaa
    24421 agagtatgtg gacaactttc atccggcagc agagaagatt gtgaagaact tctggcctgg
    24481 accattaact ttgatattta agatcaaaaa agacactttg ccctcagttg tgacgggagg
    24541 attatccaca gctgcatttc gtataccgga taacaaaaaa acactagaag taatcgaact
    24601 ttccggtgtt ccgcttgtcg gtccaagtgc aaatacgtcg ggaaaaccaa gtccaacgac
    24661 tgcagatcat gtatatcatg atctacaagg aaaaattacc gggattattg atgatggagc
    24721 tacgcgaatt ggtgtagaat ccactgttct tgatttaagt gatccaacag ccatgcctat
    24781 gattttacga ccaggtgcag taacgaaaga acaaatcgaa gcagtcatcg aatctcctgt
    24841 tgctattgat cagcatcttg taaaagaaaa tgaaacacca aaagcccctg ggatgaaata
    24901 caaacactac tcacccgata cacgtgttct gatggtcaga gatggcgatt ggtcaactgc
    24961 agttcaatgg gcaaaaaata agaagatccg tgcaggtgtc atagcaagcc ccgaaattgc
    25021 ggatcaagtg cggacagata ctgcagctgt ttatatgtat aacgacaact cagtagaagc
    25081 ggcggctaaa ggattgtttg caggtctaag aggattagat gaaccaacac ttggattaga
    25141 tttgattttt gtacaagtgt atccagaaac tggattgggg aatgcttaca tgaatcgctt
    25201 gaaaaaagca gcaggacaaa attattttga aaaatgatca attggttatt gtcgcattct
    25261 tttagtatga tacaatgcta tcaagtaaat cttctatcag tgaacgaaaa actaagcgta
    25321 actaatcgta atagaagaga tacgaatatt tggcaatttg tttttgatgg gaaaaataaa
    25381 attgtaggaa aataaaattg taggaaaata aaaaggagct gttgtttgtg gtagattaca
    25441 aaacgtttga ccctgatctt tgggctgcga tcgccaaaga agaagaaaga caagaacata
    25501 atttggagct gattgcctct gaaaactttg tctccgaagc agtgatggct gcacaaggaa
    25561 gtatcttgac aaataaatac gcagaaggtt atccagggca tcgctattat ggtgggtgtg
    25621 aatttgtcga tatcgttgaa aatttagcga ttgaccgtgc aaaagaatta ttcggagcga
    25681 aatttgcgaa cgtccagcct cactccggct ctcaagccaa cacggctgct tatctcgctt
    25741 tggtagaacc aggggacacg atcttaggaa tggatctttc cgcaggcgga catctaacac
    25801 atggatcacc agtcaacttc agtggcaaaa cctatcactt tgttgcttac ggtgttgatc
    25861 cgacaacaga agttattgat tataatgtgg tacgtatttt agctagaaaa catcaaccaa
    25921 aattgatcgt agcaggtgcc agtgcttacg gacgaacgat cgactttgcg aaattcagag
    25981 aaatcgcaga tgaagtaggc gcaaaactga tggtagatat ggcacatatc gcaggattag
    26041 tagcagcagg acttcatcct aatccagttc cttatgcaga tatcacaacg actaccactc
    26101 ataaaacatt gcgtggccct cgaggcggca tgattttgac aaacgatgaa gcattagcaa
    26161 aaaaaataaa tagtgcggta tttcctggta ttcaaggcgg ccctctagag catgtgattg
    26221 cgggtaaagc agtagcattc aaagaagcat tagatcctgc atttaaagaa tatagtgaac
    26281 aaatcatcgc caatgcaaaa gcaatggtca aagttttcaa tcaagcaatt ggaaccagag
    26341 tcatttcagg ggcgacagat aatcatctga tgttgatcga tgttcgcgag ttaggtataa
    26401 atggaaaaga agcagagagc attttggaca gtgtgaatat cactgtaaat aaaaactcga
    26461 ttccttttga aacactaagt ccattcaaaa caagcggtat tcgaatcggc acgccagcaa
    26521 tcactactcg cgggttcaaa gaagaagatg ctgtaaaagt ggctgaacta gttgtcaaag
    26581 cattacaagc aaaagatgat aacgctcaac tagacgaagt caaaacaggt gtacgcgaat
    26641 taactgaaaa atttccgttg cataaaaaat aaaaatttaa attccattag taaacagaaa
    26701 agttcaatgt tgggcttttc tgtttatttt ttgggaaaac ggattctttg acaatatcgg
    26761 tgatgctctc tagtatatga ggtgtaattt tagtcttcac actaaatctc agggaggaaa
    26821 agtcatgact gatcgtatct cgttagaaaa ggaagcagta gcattcagtg atgcaaatgc
    26881 gcctcatccg cgtatctatg aactagcacc ggaagaagga agagttttac tagaagaagt
    26941 acaagaatca cctgtgaaca aatattccgt cgatattgaa gacttgatgg tggatactgg
    27001 cgaatgggga aaactcaata ttcgtctcgt acgaccagaa gggaatatgg ataaattacc
    27061 agttattttt tatattcatg gagcaggctg ggtttttggc agtgctcaaa cccatgataa
    27121 attgatcaga gaacttgcgg ttcgtacgaa ttccgtcgtt gtctttccag aatatagtcg
    27181 atcaccagaa gcaaaatatc caacagcaat tgaacaaaat tatgctgtgt tgcaacagct
    27241 gaataaatta gccaagtcaa aaaatctgga tctcgagaat ctaatcgttg caggagattc
    27301 agtaggtggt aacatggcta cagtcatgac gatcttaaca aaagaacgaa agggcctccc
    27361 aatatccaag caattgctgt attatccagt cacaaacgct gattttgata cagattccta
    27421 tcatgaattc ggagaaaact attttttgac aagagaagga atgatgtggt tttgggacca
    27481 atatacgacg aatgaagaag agcgtgctga aatcacagct tcgcctttga gagcaaatat
    27541 aaatgaacta aatgatcttc cttcagcaat gattttaacg ggagaagcgg atgtattaag
    27601 agatgaaggt gaggcttatg cgcgcaaact tcgtgatgca ggggttcctg ttacacaagt
    27661 acgcttccaa ggaatcatcc atgattttgt catggtaaat gctatggatc agacaaaggc
    27721 aacgcgtgca gcaatggcat tatctacttc ttggatcaag aaaaaagaat aagctttgct
    27781 tgtccgcagg aaaacttctt ttcaaaaacg gattttctta ggaaaaatgg cgagtttgac
    27841 tagtcaatca cttgattttg ttttacaatt aaaaagaaac gacagaacaa aggagagctt
    27901 aaaaaatggg caaatttcaa gtgatcgatc atccattgat tcaacacaaa ctaactatta
    27961 ttcgggacaa aaactgcgga acaaaggttt ttcgtgaagt agtcgatgaa atcgctatgt
    28021 tgatggcata tgaagtatca cgggatatgc cattggaaga catcgtgatc gaaacaccga
    28081 tcactgaaac aacacaaaaa acgttgtctg gtaaaaaagt agcgattatt ccaatcttgc
    28141 gcgcaggtat tggaatggtt gacggtatct tggaattgat tccagctgct aaagtgggac
    28201 atatcggtct ttatcgagat gaagaaacat tggaaccaca tgaatatttc gtcaaacttc
    28261 cagaagacat tgatgcacgt cagttgtttg tagtagatcc aatgttggca acaggcggat
    28321 cagcaatcat ggcaatcgat gcattgaaag aacgtggcgc gtcgaacatt aaatttgttt
    28381 gtttggtagc agcacctgag ggagtaaaag ctttgcaaga agcgcatcct gatattgaca
    28441 tctatacagc ttctctagat gaaaaattga atgaacatgg ttatatcgtt cctggactag
    28501 gggatgcggg tgaccgtttg tttggtacaa aataagtaaa tacgaaaaag ggtgtgacac
    28561 aacttttgtc acatcctttt ttggtcattt ttaacgtttg atgcagaaca gctttttcac
    28621 agctttcgtt tgcatataaa aaaaccatcc caaaaatgca gagatggtca aattcaaatc
    28681 ttttttagtt ctttgtagtt aacgattact acacccttac tttgcgtcat caagttcgca
    28741 ttttctgcag tttcatcaat ctcaacaaca gcggaatttt tcaattgctt tgaaatcgtt
    28801 ccagtttgcg acttgccgtg aattgtgaac attacgtgag tattgatctt gaatttttca
    28861 ccaatttccg atggtacgat agttgtatca aattttccaa aagttgccat tttcataaaa
    28921 cctgcctttc acatcaatta taccacgttt tatgaaaaat atcatgaaat taaactaatt
    28981 ttccatcgga ctctttacaa tcagccaaat agagtatata atttcttttg gataaggcca
    29041 gcttagctca gttggtagag caacgcactc gtaacgcgta ggtcgtaggt tcgatcccta
    29101 tagctggcat taaaagagaa gacagatata tcaaggattt ttaatccatt gatacatctg
    29161 tctttttgtt taaaggaaat aaagtatgct ttcttagcaa tagagcatgt attatttcta
    29221 taaaaattta ggagaataaa acgactagca atatagctgt gaaatcaaat atcacatgaa
    29281 ctgcccaact tgtaatgatc gagttgcttt taatggcagc ttggttgaat aacaatcttg
    29341 ccaccccttg tatcaaaagg atgtgtgcta cagtgtgtaa aatatttcca ttatcataag
    29401 tactgtaatg gataaatcca aagatgattg ctgacaagaa actagcgaca ggaatgctga
    29461 acttactaga aaaaatagcg agaaaataca ctgagaacaa ttcttctcca agtatcatga
    29521 taggcaaaat aataaataat aacgggctga aagcctcatt tattggattg cctgttaaac
    29581 cccatttcaa aatttgttgc aaaaataccg agactgcggc actgattact acattgataa
    29641 aaaaatattt ggctatattt ttgacaggag cgacaggttt cgagaacatt tttttcgtat
    29701 cttttttacc aaaaacaagt gtaaatgcta taaatccagt gatagttaaa gaaaaaatgc
    29761 taataatgga tggcgcaaat agcaacccta acaaaccgag tacaacgaca atagtgccca
    29821 atatcccttt tttaagttct attttttttc ctaaaatgtt attcatgata ataactccta
    29881 ctattcagtt tttgaagata gagtcagtat acatgaagag ttaaaatagg caatgttttt
    29941 ttatggatat ttgtattgct aaaaatttat cttatatatt cattttgatt atactacttt
    30001 tatttgtaaa aattttctag caaaaccaag tgcttgcaac tgattaagcg tacaattttt
    30061 tagatgttcc gagcgtactt caatcatttc aaaggagttg ctacttaaat cgatattttt
    30121 taaatcagta tcaaaaaagc tagcattttc taaatcatta gtagaaaaca ttattttagt
    30181 gagggaacag tctacaaaat ctgcgcttga taagacagag tgctcaaagg tactttcttt
    30241 tatgtttgaa ccagataaat ttacatagtc cattttacaa ttctcgaata acgtgttccc
    30301 aatataactt tccatcaatt tagtacctgt taatttacaa ttgacaaatt tcacgcgatg
    30361 caacatgctt tttgtcaata tacagcctga aaaatcacag ttttcgaata tacagtcggt
    30421 aatctccatt ctttgaaaat cattggaagc aaaaaatgca tacttgaaaa tagatttgta
    30481 aataattgga tggcagatta tttggttttc gatgacctct ttttgtgaaa ggatattata
    30541 cagttcaaaa tcttcgtttt catagatatg aaaaaaggat cctttattca agcttgcttc
    30601 attaacttta ggaaaaatca tatttaatta cctccatttt cataaagtca tattaacaaa
    30661 agctaaacca acttacatta gcagaaaatg agataggttt tcgccttttt cgataacgat
    30721 agtgtcgcta tctcttgaaa cgttcttaga attgccctga gagacacaaa ttaggcgtaa
    30781 ttctaataaa aatcttagaa taaaaatttt tactgattta atttagaatg tttttaaaat
    30841 aaaaatcgtt gccataacag tgtattgaaa ggttttaaca atccagtaat gatttaaaaa
    30901 aatctagatg tagcgtatac tttgtttata gaatgtagtg ggaagaaata tatttttggg
    30961 aggaaatcgt gatgtctaaa agtgaagaaa tagaaaacat ggtactaaaa ttatatgatc
    31021 tcgttttaaa tccagagatc aaagaaaagg aacgtatact tttgatagac gcaaagacag
    31081 gcttagaaaa aggtcagtat tatcctaaag tcataaataa tttggaacgt agtttacgtc
    31141 cgttagcaat caggggagaa ttgtctaaac cagtatcacc gttttatatg gagatatcaa
    31201 caataggaaa atttgaaaaa gaattaggtc gaggaatggc ttcggcaccg attacttttg
    31261 ggcatttata aaaacgagtt attcatctca atgaattaaa aagtatagtc aatctcataa
    31321 tgcaggctag gttcatttat ttgaacagag tctgtatttt tttattctaa ataaagaaac
    31381 agatgtttct ttatattgta ttttatcctt taattaacac aaaaacagct agtataaact
    31441 aataatgtta attaaaagtg tattttatga aactatcgtt atttattaat gttgcatttt
    31501 tgtaagttaa aaattggaaa tatagattga aaaaatgaaa gcaataagta aaataaaatg
    31561 aatatatgcg aaaaaataat ttacattagg aaaaaccttg taaaaacagt tttttggcat
    31621 atttattttt tataaatatt tgtaaaataa ctatcaattt tttagttaaa agattggaaa
    31681 tgagtggggg aggaattgaa gaaaggattt ttgagagatg atatagtagg ttttattttt
    31741 agttaaaata ggggagatag aaaaaatgaa aaagtgtaga aatattattt tatcaatgtt
    31801 atttattatt actaatataa catcactgat tcctgttcat gtctatgcgg atgcaggcag
    31861 agatatcagc agtaatgtca cttcgttgac cgtggaccca acgaatatta cagatggagg
    31921 aaacataaaa gtaaaattct cgtttgacga aaaaaaacaa aatatccaac caggtgatta
    31981 tctttggatc aattggccaa gtgaaggaaa tattcgcggt gaaggattcc aaaaagaaat
    32041 cccattaatg attgaaaata aaaatgttgg aactttaacg gtcagaaaag attctgcgca
    32101 ggttgtgttt aatgaaaata ttaaaaacct agactcagta gaaggttggg ggcaatttga
    32161 gatacaggcc agaaacgtaa ccgataccgg tgaagaaaat acgggaccat tcaccgtgac
    32221 gagcggtgat aaaacagcta ctgtaaatgt gacaaagcca gcttctggtt cttcttctag
    32281 cgttttttat tataaaacag gagacatgct acctgaagat actaagcaca ttcgatggtt
    32341 tttgaatatt aacaataacg gcacttatgt tgaacaacca gttaaaatca gtgatgaaat
    32401 ccaaagtgga caaagattag atccaagtac gtttgaaatt aatcaaatac acttaggtga
    32461 acagaaggtt tatagaggag aagagggaat ccaacaattt ttacaagatt tccccagcgc
    32521 tacatttaat ttttcagtaa ctgataatta cattgaaata actataccaa aaaactttgt
    32581 caatcttagg aaaataatgg tgagttataa gacgatcata gaaaacccag aacaaataaa
    32641 ttttgagaat cattcggaag cttggtttaa agaatttaat aaacctgctg ttgatggaga
    32701 aagtttcaat catacagtta aaaatatttc agcttctggt ggagtcaacg gtacagttag
    32761 aggcgaattg aagattttca aatatatcaa tgacacagag attggtatcc caaatgtgac
    32821 tttcgaatta agacgagcag atgaacagcc tattcaagga cagtctagta tcctgttgac
    32881 ttcgaatgaa cagggagaag ctagtatcaa aggcctgcaa gtaggagact atgttgtaaa
    32941 agaaaaagaa gcacccaatt ggattgattt tgatccacta agttcaaatg aactcaaatt
    33001 ctccataaac gaaaatgata cagagggagt cagtttacct atttataaca agaaaaaggt
    33061 tacgaacatc acagcaacta aaatttggaa cggtggaacc actccaagac cgagtattta
    33121 ttttaaatta ttcagagcaa gtacaaacaa ttgggaacca gttcctgatg cagaaacaaa
    33181 acgattagac aatggaataa cttcagtgac ttgggaagat atccaacagt atgatgatag
    33241 tggaaacgaa tatacgttta aagtgcaaga agtagatcaa aacggaaatg attatgtccc
    33301 ttcaggttat caaaaaattg aaaacgggct agtcgttaca aatgagaata aagaagtcat
    33361 ttcagtctca ggacaaaaaa catgggaaga caatgagaac caagacggca aacgaccgac
    33421 gacgatcaca gtaaatctat tagccgacgg tcaaccgatc caacacaaag aagtaagtga
    33481 aaaagatgat tggcgctatc gtttcacaaa tctgccaaaa tacagagacg ggcaagaaat
    33541 catctatact gtaacggaag acaacgtgcc cgaatacagt acgacgattg acgggtataa
    33601 catcaaaaac agttatacac cggaaaaaac aaatatatct ataccaggta gccatataac
    33661 accgtggaaa aattttccag agaagacaga gagagagaaa attagaaatc tattctctca
    33721 aaaattgcaa atatttgctc atacaggaga atccagcgaa caaagaagca attatattag
    33781 taagagagct gtacctaaac agataacaaa taaatcaaaa agcattcttc ctaaaacaag
    33841 tagtaaaaaa tctagttttg ctgtaatcat tggtttattg atagtaacta tctgtgctgg
    33901 gatattctta caaaaatata aaaaagttta gttagaatat aatatttttt gttaaatatg
    33961 actgaaatca aaagaataaa attccgattt ataatcgaaa aaagaagcat ttttatatat
    34021 gcttcttttt tcgtagaatc aataaatatg gatttggcta actatggaag aatactcgta
    34081 ttagttttca gcgttcatac tagttgttac attgtttgat tggccaaaag aatttctgat
    34141 atattttgtg ctaaataaag aaaaagacgc ttgaattggg aaataagaaa actactctat
    34201 cattacaaat tttcataaac tggcagatgt tctaagtaaa caagtatctt ttcaaagtcg
    34261 gaaaaatcca taatcaacgt agtggtattg atatttggat gaaagcctac ggtatcttga
    34321 cgatcaatag cagcatcgat cacgacttgg atttttttct ctttgtcgtg catcaatgct
    34381 aatggagtca ctgtacctgc tggaacgcct aggaggtcag gaagctgttc ttcagaaaca
    34441 aaagataagc gcttttcttt taattgttca gctagttgtt ttaaatcggc gtgcttttca
    34501 tcaggcaaga tgacaagata gatttgtttt ccttttcttg atttcaataa tagatttttt
    34561 acttgcggac caggtaggga aaaagggaca tttttgactg acgtaatcgc aggatgatcg
    34621 actttttgaa aagagatacc cagttttttt agtagttcat aagcttcttg ttcggttgca
    34681 cgactcatcg cgcatcaccc tccttttttt attagtgtat cataaaaaag agttgacaaa
    34741 tgaaaaataa tcatgtaaat tacacgtaaa gttaaaacaa atgacatcga aaagaagagt
    34801 agccgttagg tgtttttaga gagtctctgg ttggtggaaa gaggcagcag ttaaccgtga
    34861 aacacatctt ggagtcgatt ttctgaagcg tatagtagga aaatccgggg agcccgttac
    34921 agctgcggtc gttgctagat gaccagataa ggctggcttt tccgtgagga gtcggtaaaa
    34981 aaaggtggaa ccacgtgatt aacgtccttt gatcttcgga tcaaaggact ttttgttttc
    35041 atctgaacgg caacgactgt gtgaggtttt ttctgcaagg aaaaaataaa cagaggtgga
    35101 accacgtata atacgtcctc ttggcatttg ccaagaggat ttttttattt taaaggagga
    35161 aaagaagatg gagtatttga ttgaagttat gccgcaatta ttagtaggag cactcacaac
    35221 attgaaatta tttttattta ccttgattgg ctcattacca ttagggattg ttttagcatt
    35281 aggattgtct ttgcatttta agccgctacg ctacttgctt caaacatatg tatgggttat
    35341 gcggggaaca ccgctgttgt tgcaactgat ttttattttt tatgggttgc cgacgattgg
    35401 gatcgttttt gatcgtttcg aagcagcact cattgccttt atcttaaact atgcagctta
    35461 ttttgcagag atctttcgtg gagggataca atcgattcct caaggtcaat atgaagcagc
    35521 gcaagttttg caattaagtc cctttcaaac ggtgacgaaa atcgtcatcc cacaagtgac
    35581 aaagattgtt ttaccttctg tagggaatga agttatcaac ttggtcaaag attcttcctt
    35641 gatctatata ttaggtttag gtgacgtaat gcgtgctggg aaaatcgcga tggaacgcga
    35701 cgcgacttta ctgcctttgc taggcgtggc aatcatctat cttacattga ctggtattct
    35761 aacaatcgta atgaaacaag ttgaaggaaa attaaattat taccgctaac tgataggagg
    35821 aagaaatatg attgaattga agaaagtgaa caaagcattt ggtgaaaaaa aaataatcaa
    35881 agatttgaat ctaatcattc cagatgggaa aacattagct atcgtaggtc cttccggtgg
    35941 cggtaaaacc acgcttttac gtatcttggc tggcttagaa agttctgaca gcggagaatt
    36001 ttatttagac ggtgtaccgt tcaacccatt cgagcttaaa atgaaagaac aagttgtagg
    36061 agtcgtattc caagacttcc agctatttcc acatctgaat atttttgaaa acattacctt
    36121 agcaccaaaa atggtattga aacagacaaa agaagaatac accaaaaaag cagaagaatt
    36181 agcggcttca ttagggatta gtgatttatt gaatatctat ccttatcagc tttctggcgg
    36241 acaaaaacag cgggtagcga ttgccagagc attggctatg aatccacggg tattggctta
    36301 tgatgaacca acaagtgctt tagatcctga attacgccag caagtcgagc gtttgatcct
    36361 atcattgaaa gaagatgggg taacccaaat tattgtcacc catgatttag tatttgcaga
    36421 aaatgtcggt gatcaattac taaaagtttc cccaattcat taagaaagga gaagatagag
    36481 atgaaaaaaa ccagttttct attcgctttg atcgcaggtc ttcttctttt tgcaggctgt
    36541 tcgaacaaaa aaacttcagc agataattgg gcgactatca acgaagagaa aaaaatcgtt
    36601 ataggtttag acgatacatt tgttcctatg ggatttagag ataaagacgg gaagctcaca
    36661 ggatttgata ttgatttagc caaagcagtc tttgaacaat atgggattac ggtagacttt
    36721 cagcccattg actggtcaat gaaggaattt gaactgaaca atggaacgat cgatttgata
    36781 tggaacggct attccaaaac gccggcaaga gaaaagaaag tgcaatttac aaaaccttat
    36841 atggaaaacg atcaagtgct gatcacacct aaagaatcag gaatcacaaa ctttggacaa
    36901 atgaataata agagattagg tgcgcaaaat gggtcatctg gttatgatgt atttacgaaa
    36961 caaccagaag tattaaaaga gatagtcaaa aaccaagatg ctgttttgta tgatagtttt
    37021 aatgaagcat tgatcgatct gaaaagcaga cgggtcgatg gtctgctgat ggataaagta
    37081 tacgcagact attatttgaa acaaagaaac gaactagaag acttcaacat aacaaaaggt
    37141 tcttatgaga gtgaggattt tgcagttggt gcacgcaagt cagatagtac attagtgaaa
    37201 aaaatcaatg aagccctaga tcaactagag aaaacaggtg aattccaaaa aatatccgat
    37261 aaatggtttg gcgaagatgt tacgccgaga aattaacaaa taggggactg tgacaaaaga
    37321 cgtgtcacag tccctttttc cgaataaaca gtgttctcct gccaactcct tgtgactcgg
    37381 agctgaatgg caggctcaca acctcttggt aaacggtgtt caaaagccag tttttcggta
    37441 ttaagccaaa tttatgcaaa aatgtagaaa gccattttca caaaattttt cttactactc
    37501 gaaactaagc gactttttca caacctcctt tacataattt tattttgttg tggaaggggt
    37561 ttcgtgttat tctaaaagag gaacgattga aggttatagg aaaggaagag atgaatggaa
    37621 cacaaagaac ttacctcatt tccaaaagat tttctgtggg gctctgcttc tgcagcgtat
    37681 caagtagaag gagcttggca agaagatggg aaaggagaat cagtctggga tcgatttgta
    37741 cggatacctg gaaagacatt taaaggaacg aacggtgatt tggcagtaga ccactatcat
    37801 cgttataaag aagatattgc tttaatgaaa gaacaaggtc tgaaagctta ccgcttctct
    37861 gtagcttgga cacggatttt tcctaatgga cgaggagaag tcaatcaagc tgggctcgct
    37921 ttttatgaga gattgatcga cgaattgatt gaaaacgata ttgaacctat gttgacttta
    37981 tatcattggg atcttccaca agcattgcaa gatgaatata atggttggga atcacgtcag
    38041 atcattgaag atttcactca ttatgcagaa acattatttg aggcattccg cgggaaagtc
    38101 cattactgga ttagtttgaa tgaacaaaat atcttcactt cattaggtta tttgttagca
    38161 gcacatccgc caggtgtgac agacccgaaa cgaatgtatg aagttaacca tattgctaat
    38221 ttagcaaatg catctgtcat caataaattt cacgagttag aaatgcctgg aaaaatcgga
    38281 ccaagctttg cgtatacgcc aaattatcca attgacagta atcctgaaaa tgttctggct
    38341 gctgaaaatg cagaagacct gatggccaat tattggatgg atgtctatat gtggggaaaa
    38401 tatccgattg ctgccatgag gttcttagaa gaaaaaggat gggcaccaac gattgaagct
    38461 ggcgatgcag aattgctaga atctgctaaa ccagattttc ttgggatcaa ttactatcaa
    38521 acggcgacga atgcattcaa tccattaaac ggagttggtg ctggaaaaat gaatacgaca
    38581 ggaaaaaaag gttcatcaga agaaactgga gttcctggaa tgtataaaaa agttgagaat
    38641 ccatttgtcg aacgaacaaa ttgggactgg gagattgacc cagaaggatt aaggatcgga
    38701 ctgcgtcgta tcacaagccg ttaccgcatg ccggtactga ttacggaaaa tggcttagga
    38761 gagtatgaca agttgacaga agataaacaa atccatgacg actatcgaat caattactta
    38821 caaagccacg tcaaagccat caaagaagca atttcggatg gagcagaagt cctaggctat
    38881 tgcacctggt cttatacaga tttgcttagc tggctgaacg gttatcaaaa gcgatatgga
    38941 tttgtatatg ttgatcaaga cgaaacacaa gaaggatctt tggaacgata taagaaagac
    39001 agttattact ggtaccaaaa actgattgaa gaaaatggag agaaccttta gttcacatac
    39061 ttaaaacaag aaggtacggc tggatatggc cgtgcctttt cttgataaaa tcatttagaa
    39121 attaagaaaa actgtaaaat aagctgaaaa atgaaagaaa gcgtcagttc tttcaaacaa
    39181 aactttagtt cccttacttt tttttgtata atgaaacttg atgaaatgag ggataataaa
    39241 tggcacaaaa gaaacggcct actaaaaaaa ggaaaaagac gaaaaaaacg aaaaagcaaa
    39301 aacagcagca ggaacaaatg ctgacgattg gtgttgggtt tgccttgatt ttatttgctg
    39361 tcttcggctt tttaaaatta ggttttttag gaatattgat tgcaaacggc tttcggatca
    39421 ttgcaggaaa tacttaccaa atcctctgtc ttttattagc cgtattagga ttttggattg
    39481 tcattaagaa tacagagttt tcaattggta aaaaccgacg ctggtttggc ggcatactct
    39541 tttatttcgg tatcttatta ttgttacatg cccatttatt tggcaaactc catactgggg
    39601 aaccaaatat catggggacg acatgggatt tgttagccag tgatataaaa caaagtcaag
    39661 tagacaataa cgttggtggt gggatgattg gagcaatcct ttatcatttt acttacttct
    39721 tgattgcaca gcctggaagt tatttagcag cagtgctatt actggcagga ggagcattcc
    39781 tgttcagtaa tctggaaggc tatcagctgt taaatggtat ccaatcaatt ggagaacgag
    39841 tacaggaatt attggaaggt gatcctgcca agcaagctcg aaagcaagcg gcaaaggaag
    39901 agagaatgaa acagcgcgca gaagcgaaag aagcaaggcg cttagctgca aaagaagctg
    39961 cagaaaaaga agctgcagaa tatgagaaga aaaaagcggt gagccagcaa agggaaaata
    40021 ctgctgatga atggcaggaa ccagaaaata cagagccgga gcagctaagt tttgttccaa
    40081 tcgacagttt tcaagaaaat atccatcctg cgaatctaga gaaaccagta ccagatacac
    40141 caaaacagac caatacagca gaaggttttt cagatgagtt gccagaggat gacggtacct
    40201 cattagaatt tgagattgaa gcagaacagg aaaatcaaga ctatgaatta ccgacagttg
    40261 atttgcttga ttctatacca actgtggatc aaagtgatga gtataaaaaa attgaaaaaa
    40321 atatcggcgt attagaacaa actttccaaa gtttcggtgt cgatgccaag gtcgtcaaag
    40381 ccagcttagg accatccgtc acaaaattcg aagtccagcc ggctgtaggg gtaaaagtaa
    40441 gtaaaattgt gaacttaaca gatgatatcg cgcttgcttt agcggcgaaa gatgtccgga
    40501 tggaagcacc gattccaggt aaatcactga ttggtattga agtaccaaat ggaaagatca
    40561 gtatggtttc ctttagagaa atcatcgaag cacaaccaaa ccacccagat aaattactag
    40621 aagtaccttt aggacgtgat gtttctggac gggtacaaac ggctgatctt tcgaagatgc
    40681 ctcacttact cgtggctggt tcgactggta gtgggaagtc agtagcaatt aatgggatta
    40741 tcacaagtat attaatgcgt gctaagcccc atgaagtaaa actgatgatg atcgatccga
    40801 aaatggttga attgaatatg tacaacggca tacctcatct gttgacgccg gtcgtgacga
    40861 accctagaaa agcagcgcaa gccttacaaa aagtagtaca agaaatggaa gaacgatatg
    40921 aaaaattcgc ggcaaccgga gtaagaaata tttctggtta caatgaattt gttcaacaga
    40981 aaaacttgga aaacggaacg aaacatccaa ccttaccatt catcgtagtg atcgtagatg
    41041 aattagctga tttgatgatg gtagccagca atgaagttga agatgcgatt attcgtttag
    41101 cgcaaatggc tcgggcagcg gggattcata tgatcctagc tactcaacgt ccaagtgtgg
    41161 atgttatcac aggaatcatc aaagcaaatg taccttccag aatggcattt gcggtatcaa
    41221 gcggtacaga ttctcggacg atcattgatt ctaatggggc agaaaagctc ttagggcgag
    41281 gagatatgct attcttgcca atgggtgaga ataaaccgat ccgtgtgcaa ggagcattca
    41341 tttctgacca cgaagtagaa cgggtcgttc aatttgttac agatcagcaa gaagctcatt
    41401 atgaagagaa aatgatgccg acagatgaag ttgaaacgac aggtgctcca gaacagccac
    41461 aagatgagct gtttgaagaa gcaaaagcac ttgtcgttga aatgcaaacg gcaagtattt
    41521 cccttctcca aagaagattt cggatcggtt acaaccgagc agcacgttta gtagatgaac
    41581 tggaagctca tggagttgtt ggcccgtcag aaggaagcaa gcctcggaaa gtattcattg
    41641 agcaggaaga aacatcagaa acgttgccgg acgataatga catgtaaaac ttgtgtgatg
    41701 aagggttgaa aaacgaataa ccaataaaaa gacaaggcat gatgatacca aaagaaaaaa
    41761 tggttttttt ccatcttttc taatacggta tgatgtcttg tctttttagt ttttgtgaga
    41821 ttaaagttct attcgattta tttgtgaagt attgcattaa ggaaatgaat catgtatagt
    41881 atgtagcgaa actttgagaa aaagagggaa aatactttgg aaaaacagtc catttatggc
    41941 ttgacgaatg aagaattaat caattggttt atagaaaacg gcgagaaaaa attccgagct
    42001 gcccaagttt gggaatggtt gtatcaaaaa cgtgtaagta atttcacaga aatgacgaat
    42061 ctatcgaaac aattgatcga aaaattatcg gagcatttta tcatcaatcc tctaaaacag
    42121 atggtcgtcc aagaagcttc ggatggtaca gtaaaatatt tgtttgaact ccctgataaa
    42181 aacatgattg agactgtact gatgagacaa gaatatggct tgtcagtttg tgtgacgaca
    42241 caagtaggat gtaatatcgg ctgtacgttt tgtgcaagcg ggctgctcaa aaagaaccgt
    42301 gatctgactg ctggagaaat tgttgcacag atcatgatgg tccaacatta ttttgatgag
    42361 cgcaatcttg gcgaacgcgt ttcacatgtc gttgtaatgg ggatcggtga gccatttgat
    42421 aattacgaca atgtaatgga ctttttgcat atcatcaatg atgccaaagg attggcaatt
    42481 ggtgctcggc acattacagt ttccactagt ggattagcac acaaaatcaa ggaattcgct
    42541 aataacggct tgcaagtcaa tctggctatt tccttgcacg cgccgaataa tgaggtgcga
    42601 acatcgatca tgcggatcaa ccgaagtttc ccaattgaga aattgatgga agctgtggat
    42661 gagtatttag agaaaacaaa ccgtcgaatc acgtttgaat atatcatgtt gaatcaagta
    42721 aatgatagac cagagcatgc gcaacaatta gcagatctat taaaagataa gaaaaaatta
    42781 gcatatgtca acttgattcc atataatcca gtcagtgaac atgatcaata ttctcgcagt
    42841 ccaaaagctg atgtattgag attttatgat gtattgaaga aaaacggcgt aaactgtgtg
    42901 atacgtaaag aacatggtac agatattgat gcagcttgcg gacaattgcg aagcaagcaa
    42961 atgaaaaaaa cagttgccaa ataatcgtat cctactcgtt ttttcaatta ccataaaagg
    43021 agcagttttc ttaattaagg aactgttcaa cttaaataag agaaaagatt ctatagcgaa
    43081 agctataaag ctttttttga caagaaaaac cctcatcaag caaagaaatg tcctcaattt
    43141 gatgacagcc tgcttgatgg gggttttagc aattatttaa ctgattttct tatatccttg
    43201 ctggctttct tgtgtagcat gataagtttc tacgtcaaga atggcctgtt taaatttttc
    43261 tcgggtgatt tcataaggca catgtttaat atcatttgtt gccatggctt tatctaagat
    43321 tgcttctaaa tcggtcgtga cattgagatt catgtcggtt aacgatactg gaagttggtt
    43381 ctttttcata aacacataga ttttatcaaa caaatcgaac tgctgatcca tcatcaataa
    43441 ggtcagtaca ccataactga cagatgctcc gtgaaggtat ccctccattt tttctagaac
    43501 agtcgtaccg taatagaatg agtgtgccat agcagaatta tagttattgt taactaaaac
    43561 agaaaccaat ccggtagtaa caatgatatc cgaaacgact tgttcaattg catatgaggg
    43621 acgatcgtcg gcactatctt tcaatgcttg cgtaccataa gtcaagagac gatcaatgca
    43681 catttttccg atttggattc ctaatctatc cgtgtagcct agatcatcgc cacgagcaga
    43741 aaaagtagat tcgacttctt tggataaagc atcgccaata cctgcccata agtatttatc
    43801 aggtgcttcg gcaataattg ctgtatcaat gaaggtgtgt acaggtggtt ttgaaggaaa
    43861 gaagagtccg tccattacgc cttcttcgtt atagatgaca cataccgcag tgacgggcga
    43921 acagttcgaa ccaatagtgg gaaaggtgaa gactggttta gctagttttt caccaatgac
    43981 ttttacagta tcgcaagcac ggccaccacc gactgcaaac aggacgtctg ctttttggac
    44041 actttcatgc tggatcaact gttcaatatt tccataagtt gaattacccc cgtaccagag
    44101 actggcgaca acctctattt cctgtgtcaa agctactttt attttgtttt ctgcctttga
    44161 aagtgcagtc ttccctccaa tcagcactac ttttgtccca tattctttga cgattccatt
    44221 tgctttttca tacgcatctg ttccaatggt ataatttggt aagaaaacac tttgactcat
    44281 attcatttcc ttctttcttc gttgaaacgg gttaaaattt taaagagtga tcgatctgac
    44341 tgcggctgta gatggagtag aggtgaacct aagacaggat aagtgatgaa taaggtggca
    44401 tgaacacctt gaaatcatca ataagtatcc taaaaacgaa caagtacaaa aacattgaaa
    44461 acgacaataa tgaatttttg ttcctcttag tatttctacc gattcccttt gcttttttgt
    44521 aattatctaa aaattctaaa aattaagatt attatatgaa aacaggtttt atttgtcaat
    44581 tcataattgg ttttttttaa agcaaaagat aatctatatc atgatgaaca aacagagttt
    44641 tttcctccaa ttgatggctt tcctgatctt tcctattttg aataaagtgt ttctgtataa
    44701 ttttttattt tataagtaag ataaataatg aaagaataga gatactgatt ggtagctaaa
    44761 gatttttgag cgagaacatt tcgttttttc aaaaggactg ttagaataag caagaacaag
    44821 ggggaagacg tatgataatc agtgaatttg accgtaataa tccagtattg aaagatcagc
    44881 tttctgattt actgagactg acttggccgg aagaatatgg agacagctcg gcagaagaag
    44941 tagaagaaat gatgaatcca gaacgaatcg cggtagcagc ggtagaccaa gatgagttag
    45001 taggatttat tggtgcaatc cctcaatacg gtatcacagg ttgggaattg catccattag
    45061 ttgtagaaag ctcccgacga aagaaccaaa taggtactcg attagtcaat tacttagaaa
    45121 aagaagtagc ttccagagga ggaatcacga tttatttagg tacggatgat ttagaccatg
    45181 gaacaacgtt aagtcaaacg gacctgtatg agcatacatt tgataaagtg gcttccatcc
    45241 agaaccttcg tgaacatccg tatgaattct atgaaaaatt aggttataaa atcgtaggtg
    45301 tcttaccaaa tgcaaatggc tgggacaaac cggatatttg gatggcaaaa acgattattc
    45361 ctcgaccaaa ttctcaataa taaaaagagg ttgtgacaga agtaatcagc ttcaagaaat
    45421 aagaaggaat ttacgaaaat tacttcttga atttttgtga aattccaact tatttccgaa
    45481 gaagctactt ttggaacacc gtgtaccaga ggttgtgaaa aagtcgctta gtttcgagta
    45541 gtaagaaaaa ttttgtgaaa atggctttct acatttttgc ataaatttgg cttaataccg
    45601 agaaactggc ttttgaacac cgtttattca gataagggac tgtgacaaga cttttgtcac
    45661 agtttctttt tgtttattct tttttatctt tgtatggcaa taatagacaa tataacgaaa
    45721 attatttaat ggcttttgga agaccatgga aaaccttgta caaagctatt ttttctgaaa
    45781 aattccttga aacctcacga aaaaatcatt attttatgaa aaagacaaaa aaaagtgttg
    45841 attttttaat aattattcat taaactctta aacaacttca gaaaatatta attattctga
    45901 aaattccaat aaaggggtac gtaaaatgaa aaagaaattt acatttggtt tggttgcggt
    45961 atgcggcctt gtacttgctg gatgttatgg cggcagttca gccacaagca gtagttcagc
    46021 aaaaagcggt tcagcagatg gaggaggcgt atttaactta gtcgtgcctc aagaaatgcc
    46081 tacagctgac ttatcagttg caacagatac aatcagtttt acagcattga ataacgttta
    46141 tgaaggaatt taccgtcttg atgaagacag caaaccacag ccggcaggag ctagcgagtt
    46201 ggcagaagtc agtgaagacg gattaactta caaaatcaaa ttacgagaag acgcaaaatg
    46261 gtcaaatggt gatcctgtta cagcagcgga ttacgtttat ggctggcaac gaacagtaga
    46321 cccagctaca gcttctgaat atgcttacct gtatgcgcca gttgaaaatg cagaagacat
    46381 tacagctgga aagaaagata aatcagaact agggatcaaa gcagttggtg actatgaatt
    46441 agaaatcaaa ttgacgaaac aaacaccata tttccaatat ctgcttgctt tcccatcatt
    46501 tttcccacaa aaacaatccg tagtggaaga aaatggggat gcctatgcat ctgcaagtga
    46561 taaagctgtt tataatggac cattcacatt agaagatttt gatggaccag gaacagatac
    46621 agaatggact tataagaaaa atgatcatta ctgggacaaa gatacagtaa aactttctga
    46681 aatcaaagtc agtgtagtaa aagaatcttc tactgcattg aacttattca aagatggcca
    46741 agcagatgac gtgatcttgt ctggtgagtt agcacagcaa aacgcaaacg atccagctta
    46801 tacttctgtt aaagaagcgc ggacaagcta tatcgaattc aatcaacgtg aaaagaattc
    46861 accattcaac aatgtgaacc taagaaaagc tatttcttat tctatcgatc gtgaagcttt
    46921 agtaaaacaa gtactaggtg acggatcagt tgtctctaca ggattgatcc catcagatat
    46981 ggtaaaaagt ccaacaacga acgaagactt tgcaaaagaa gctggaaaat tagtttctta
    47041 tgacaaagat aaagcaaaag aatattggga aaaagcgaaa aaagaattgg gcgttgattc
    47101 tttagaattt gatttgatgg cttctgatga tgattcatcg aaaaaagtaa tcgaatatgt
    47161 tcaaaactca atccaagaaa acttggatgg cgtaacagtc aaaccaacac ctgttccatt
    47221 ctctgtacgt cttgaccgct caacttcggg tgattttgac gcagtactag gcggatgggc
    47281 tgctgactat gcagacccaa gcagctttac tgatttgttt gtcacaggta attcatacaa
    47341 ccgtggtcgc tggagcaatg cagaatatga cgaagcagtt aaagcagctt catcaacaga
    47401 cgctggcgat gaacaagccc gttgggatga tttccaaaaa gcaatcaaga tcatctctga
    47461 tgatatgggt gtcgttccgg tgtaccaaaa agcagaaggt cacctagtga atgaaaaaat
    47521 caaaggtatc gttcaccatg cggcaggcgc ttcatgggat tacaaatgga catacgttga
    47581 agaataatcg ttaataccgt gagcatgaga aaaaacgagg ctgcggcaaa tgtcgcaacc
    47641 tcgttctcat attcacttat cctaacaaag aaaaaagcat gaaaatagca gaaagagcaa
    47701 ttagtattcc ggcaatgatc agccaaaagc tgtacatacc gtagctggca gacgagagcg
    47761 tggaaaattc tggttttttc tttcggttcc ttgttcgtgc aagatggacc gatcgctgaa
    47821 aatgatcgaa gaaacccgaa gaaaagaccc ataaaaaacc gccgataatc agaaacggca
    47881 atgaccataa gaatagatca ttagataatt gaatgagtgt aaaggaatgg ttgatgagat
    47941 tttttattaa aataaccaga atcagtagaa aagctactgc gtaggggata gatttttttt
    48001 tcatttgatt gctcctttat ttttggttca ttatctaata atgtagcgaa acatctgtca
    48061 gaagtcaaaa gctaggggga aacattagtg aatagttata tcaaatatgt attaaaacgt
    48121 gtctttttca tgatcatcac gctttggtta attgcaacaa tcaccttttt cttgatgcaa
    48181 ttgctgccgg gcacgccata tacgaatcag gaacgtttga gtcctgaaac aatcgagatg
    48241 ctaaataaac aagtcggttt ggataaacca gttatcgtac aatatgggat ttatctttct
    48301 aatttgcttc aaggagattt tggaatttcc ttccaattta aaaaccagcc agtcgcacat
    48361 ttgttagctg gaagaatcgg accatccttg cagttagggt tacaggcaat tatctttgga
    48421 acagtcctag ggacgatttt aggaacgatc tctgccatga agcaaaatac atgggcagat
    48481 acatcttcta cactcgtagc gatattaggt cgttccattc caaactttgt atttgctgtt
    48541 ttattacaat atatctttgc aatcaaatta caagttttgc caatcgcaaa atgggatggc
    48601 tttgtgtaca caatcttacc aacaattgcg ttggccatgt cgccgcttgc tgactctgct
    48661 cggtttatcc gtacggaaat ggtggaagta ctgcatagtg attatgtgga attagcaaaa
    48721 gcaaaaggat tgagccgttg ggaaatcgcc tttaaacatg gtcttcgaaa tagtttgatt
    48781 ccattgatga ctttattagg accgttagct gtagcattga tgaccggatc actggtggta
    48841 gaaaatatct ttgctattcc tggtatcggg gaacaattcg ttaagtcaat cacaacaaat
    48901 gattatccta cgatcatggc tgtaacgatc ctttactcat ttatgctgat ttttgttatt
    48961 ttgatcgtgg atctattgta cggtctagtt gatccaagaa ttcgtgtttc agaagggagc
    49021 cgaggataaa tggaaatgat accaaagcgt tatgaaacag ttgcagatat ccctgcggat
    49081 gaatttcttc cattacaaaa aaataccgaa gaagaacgtg aacagattac tgcaccttct
    49141 ttgaatttta tccaagattc atggcgccgt ttaaagaaaa acaaagctgc cgttatttca
    49201 atggttttac tattggtcat cattttgatc tctgtgatca caatctttgt ttctcctcat
    49261 gatccaactg cccaaaacgt ggcttatatc aatttgcctc ctcgtattcc gggaatcaat
    49321 atcgatggat tgaatggaaa agcaatggtt ggtggtgaac ttgttgataa atatgctcaa
    49381 gcaaacgtcc cttcaaacgt aaatttcttt ttaggaacag acggtttggg acgtgatgta
    49441 ttaagccgct tatttatggg aatgagaatc tcgttgctga tcgcatttat tgctgcatta
    49501 ctagatgtaa cgattggtgt agcttacggg ttggtttctg gtttgttagg cggacgtgtc
    49561 gataacgtga tgcaacgttt tttggaaatc ttatcaggaa ttccaaacct cgttgtcatg
    49621 attttgatgt tggtcgtttt tgaaccagga attttttcaa tcgtggctgc tatggccatc
    49681 acaaactgga taccaatggc acgtatcgtt cgtgcacaaa caatgaaatt aaaagatcaa
    49741 gaatatgttt tagctggatt gacattaggt gaatcaagaa tgaaaattgc attcaaacat
    49801 attttgccga atatctctag tgtcattatt attcaaatga tgtttagtat tccatctgct
    49861 attttcttcg aagccttttt aagctttatc ggtttaggtc ttacgcctcc gtcagcttca
    49921 ttaggaacga tgttgagcga agggtacaag acattcctgt atctgcctta tctattatgg
    49981 attccggcag taactttatc ggttatcatg attggcttta acttacttgc tgatggattg
    50041 cgtgatgcct ttgatcctaa aatgaaagag tgaagacgat gacgaaaatt ttagaagtga
    50101 aagacttaga aatctctttt gatacgtatg ctggaaaggt acgagcgatt cgcggtgtca
    50161 attttcattt gaataaagga gaaacattgg cgatcgttgg ggaatctgga agtggaaaat
    50221 cagtgacgac cagaagcatc atgcgcttgc tgtcaagcaa cgccaatata gatgctggtc
    50281 aaatcctctt taaaggtaac gatatcgttg gaaaatcaga aagagagatg caaaaaatcc
    50341 gtggtaaaga aatagcgatg attttccaag atccaatgac ctctttagat ccgacgatgc
    50401 ccattgggaa gcaagtcgct gagtccctta gaaagcataa taaagtttca aaaaaagagg
    50461 gacaaaaagc tgcattagaa ttgcttaaat tagttggaat acccgaagct gagaaacgta
    50521 tcaacagtta tccgcatcag ttctcaggag gtcagcgtca acggatcgtg atcgcgattg
    50581 cactggtatg ttatccggaa atcctgattg ctgatgaacc tacaacagcg cttgatgtga
    50641 ctattcaagc acagattttg gagctgctga aagaaattca gacaaaaatc gatacatcaa
    50701 ttatctttat cactcatgac cttggtgtag tagcgaatgt cgctgatcgt gtcgctgtca
    50761 tgtatggagg aagaatcgtt gaagttggaa catcggaaga aattttctac aacccgcaac
    50821 atccctatac ttggggactg cttggttcaa tgccgacatt agatagtgcg aacgatcgat
    50881 tgtatgctat tcctggttct ccaccggatt tattgaaccc gccaaaagga gacgcattct
    50941 atccaagaaa tgaattcgcg atgaaaatcg atgcagaaca agaaccacca ttttttgaac
    51001 tatcaaaaac acacaaggca gcaacttggc tacttgctcc gcaggcaccc aaagtgacac
    51061 cgccagaaga aatccaacgt cgctgggcta tctttaaaga gaaacaaaaa catacttacg
    51121 gtcaaggagg aattgctgat gccaaataaa ctacttgaag ttaaaggatt gaaacagtat
    51181 ttcaatgtag gaaaaaagaa tgaagtacat gctgtaaatg acatcagctt tcacatttat
    51241 gaaggagaaa cattcggttt agttggagaa tctggaagcg gaaaatccac tactggccgt
    51301 acgatcattc gcttgaatga acctactgat ggtgagatat tattcgacgg tcaagatata
    51361 acgaagatca aagataaaaa aggtttgacg aaattccggc atgatgttca gatgatcttt
    51421 caagatccat acgcttcgtt gaatcctcgt atgaaagtca gagatatcat tgccgaagga
    51481 attgatgtta atggactagc taaatcatct gaagagcgtg caaaaaaagt cgatgatcta
    51541 ttgagaactg ttggattgaa tccaagccac ggtactcgtt atcctcatga attttcaggt
    51601 gggcaacgcc agcgtattgg tattgcacga gcattggcag taaaaccgcg ttttatcatt
    51661 tgtgatgaac caatttctgc actagatgtg tcgatccaag cccaagtggt caatttgttg
    51721 caagatctcc aaaaagaaca tcaattgacc tatctattta ttgcacatga tttgtcgatg
    51781 gttaaacata ttagtgaccg aatcggtgta atgcataacg gcttgttatt agagatggga
    51841 acaagtgatg aaatctataa tcacggtgtt catccttata cagaaagttt gttatctgct
    51901 attcctctac cagatccaga ccatgagaga aaacgcagaa gaatcaaata tcaacctgaa
    51961 ccagatgacg gacaagtacg tcaacttcgt gaaatcgcac cagaacattt tgtctatgca
    52021 actgagcagg aagtcccata ttacgcaaaa aaactaaaac gacaaaagga atctcttctg
    52081 gttgctaact aggagggaca tagatgctaa aagcttttaa attccgtatg tatccgacag
    52141 aagaacaaaa acagcaattg attcgtactt ttggatgtgc tcgatttacc tataaccatt
    52201 tgctgaaaaa gcggcagaaa agttggcaac aaacaggagt agccaatttt tcgctcacac
    52261 ccgctacatt aaaaaaagaa tacccattct taaaagaagt agacagtctt gctttagcaa
    52321 atgcacagct taatttggat cgggcttttc gcaattattt caagggacgt gccagcttcc
    52381 caaagcttaa aacgaaaaaa agtatgtggc aatcttatac gaccaacaac caaacccgta
    52441 cgatctatct ggaaaatggc tacttaaagt taccaaaaca aaaagaacta atcaagataa
    52501 atcagcatcg gccagttgaa ggatcgattc gctccgctac gatttctgct cgatataatg
    52561 aagaatttta tgtcgcacta ctttgtgatg tttcgccagt aaaaaaagaa tctttagcta
    52621 aatggatcgg gatcgcctat catccgaaga cattgatcca aacatctcga cctctagaag
    52681 taactttacc aaaatttcac cagacagaag aaaagctgca acatgcacag cggaaattga
    52741 atgtgaaagt ccgctccgct caccatagaa agatcaggtt agatcaggca agcaattatc
    52801 agaaacaaaa gagaaaagta atggatcttt atctgaaaca aaagaaccag cgagaagatt
    52861 atcttgaaca attatctggg aaattggtca aacaatatga ctacttattt gtagaatctt
    52921 ttccaaaaga agaggcacat gctgattttt ctattcacga ctggcataaa ttaataacaa
    52981 aattgcgtta taagtcccaa tggtataata aaaaatttct tttgatcaat accgacggag
    53041 cagaagaaag caattccgta agaaagagcc aagtagtaga aaaaatgggc agacattcgg
    53101 ttatcaaggg ataaaaaatg aatgaaactg ataggagcgt tagggttagc cttgttaata
    53161 aaaagtctta atgacttttg tttctaggaa tttttctttt gaagaaaagc tcactaatta
    53221 tgacaaacca ataaaacaat agcagaaaaa gttcgtacga gctttttctg ctattgttaa
    53281 ttttttattc agaaagttta cgaatacatc aaaattctga aacaaaaaac gtaactcaca
    53341 aagagttgtt tttgcgtttt ttcttgaatg attaggtctg aatcttttgc tcacaacctt
    53401 attcatggtg ccccggcttg agctgataga tttttgaagg acggccgatt cctacaggac
    53461 gttcaccgat ctcatcgaaa tattggagca tagctttctt aaaattggaa tgatcgatcg
    53521 ttttataatc gatccctaag aatttagcaa atacttttcg agcttccgta atcgtgaaat
    53581 ctttacctaa aacttgtaga acttgcggct cgtgttccat tttattgact acacggttga
    53641 atgctttcaa gatgatttga ctatggtcaa aagccaaagt atctttgcca gaagactctc
    53701 cagtgactaa atcaagcgag atagccactt ctccgctaga taaatggatc ttgttactat
    53761 gacgttctag tgtgaaccag cgtacttcct tggcatcatc tccggcgatt agcggttctt
    53821 ctccaataaa ggctaagtag ctgactgtga cgacccagcc tcgcggatct cgattaggcg
    53881 tactgaatgt atgcagttgc tcaatatttt cttttgaaat aaccacacca gtttcttcct
    53941 ttgtttctct taagacgctt tctccagttg actcatcctt ttggacaaag ccaccaggca
    54001 atgcccatga atttcgataa ggatgccctt ttctttggat caacaaaact ttcagctgat
    54061 cttcttcttt gttatagcac atcagtacga tatcgacagt caaagagggc ttgtcatatt
    54121 ctggacgttc ctgtttttga taccagttaa gaaattcttc ttcacttgct ttatgttcat
    54181 aatataattt ttcttcttct ttagaagcaa aacggttcat ctgaccacct ccattgacag
    54241 taaaagtact ttttacctta ttgtagcaga ctctgaaaaa aaaccaagga tttacttgaa
    54301 aaatctaggt tatcatttaa atatgaaaaa taaatggaag tatgagattg aataaaaaga
    54361 aaagcagata aaacggcaat actttatacc gctcttcacg aatggcaaag aagccacaaa
    54421 taacgatata tacgtcaatg ataaaacgca aaatccaagc tgctgtcata aaactgttca
    54481 aatgcccatg gaggttaaaa taaccataca tacgaatata aaaatagctg aatattaaat
    54541 gtgctaatga aagaaaagca atactaagtg taaaaaaaag atgtttcttc tgcatgattg
    54601 ttccagtccc ttactaagat agatagtctt tattatacca cgtgtgaggg gagaaataaa
    54661 aagccgtttt ttagtagata tgaaacaaaa caaaaacccg catttattca acctattcat
    54721 ccttttaaag gatagattga acgtagatag aagtcgttta tccagtcttt ttcattttga
    54781 aaaaaagcta acagcatgct ttttttatgg tatactagca aggaaacgaa ttcgcatcat
    54841 gcgataaagg aggaagagcc ccgtggcaga aaaggaaact ttttatatca ctacgccaat
    54901 ctattatcca agcggcaaac ttcatatcgg caactcgtat actacgattg catgtgacgc
    54961 aattgctcgt tataaacggt tgatgggctt tgatgtgttt tatctcactg gagtggatga
    55021 acatggtcaa aaaatcgaaa caaaagcaga agaactaggt gtaaaaccgc aagaatatgt
    55081 agataaaatg gcggctgatg tcaagaaatt atggaaaacg cttgatatca gttatgataa
    55141 attcattcgc acgacagatg attaccataa agcagctgtt caaaaaatat ttgatcgttt
    55201 attagaacag ggagatattt acttaggtga atatgaaggc tggtactctg tttctgacga
    55261 agaattcttt acagaaacac aacttgcaga agtgtacaaa gatgacgaag gtaacgtgat
    55321 cggtggtaaa gcgccaagtg gacacgaagt agaattggta aaagaagaat catacttctt
    55381 ccgcatgagc aaatacgcag accgtctatt ggaatactat gaagaacatc ccgaattcat
    55441 ccagccagaa tctcgtaaaa acgaaatgat caacaacttt atcaaaccag gattagagga
    55501 tcttgcagtt tcacgaacaa cttttacttg gggagtacca gtcaagagtg atccgaaaca
    55561 tgtggtgtat gtatggatcg atgcattatc caattatatt actgcactag gatatggctc
    55621 cgaagatgaa agtctattcg aaaaatactg gcctgcagat gttcagatgg tcggtaaaga
    55681 aatcgttcgc tttcatacga tctattggcc aatcatgctg atggcccttg atttgcctct
    55741 acctaaaaaa gtatttgggc atggctggct attgatgaaa gacggaaaaa tgtctaaatc
    55801 aaaaggaaat gtcgtttatc ctgaaatgct tgtggaacgt tatggtttag atgcactccg
    55861 ttattatttg cttcgtgctg ttccgtttgg gtcagatggt gtctttacgc cagaagattt
    55921 tgtttcccgt gtcaattatg atctggcaaa tgatctaggg aacttattga atcgaacgat
    55981 tgctatgatc aacaaatatt gtgatggact cgttcctgac tatgcctcac ttgtcactcc
    56041 atttgatagt gaactgtcta cgacggctgc taacgttgtc ggacgttacc atgatgcaat
    56101 ggaaaaaatg gaattcaata cagcattggc tgaaatctgg gtgctgattt ctcgtgcaaa
    56161 caaatacatt gatgaaacag aaccatgggt attagcaaaa gacgaagaaa agaaagctga
    56221 attgaatagt gtcatgatcc atttagctga atctttgcgt atcgcagcga tattacttca
    56281 gccaatcatg acagaaacgc cagagaagat cttcaatcaa ctaggattgg actctgaaac
    56341 aatgaatctt gaaggattac actttggcga atttccttca ggaacaaaag tagttgcaaa
    56401 aggtacacca atcttcccac gtttagatat ggaagaagaa gttgctttta ttcaagaaaa
    56461 aatgtctgaa ggtactcaaa caaacgaaga tacagtcaaa tgggatccag aagaaacaga
    56521 acttgtttca acgaaagaaa aacaaatcaa atttgatgta tttgaaaaag tagaactaaa
    56581 agtagcagaa gtcatcaact gtcaaaaagt agaaggggca gataagttgc tgcaattccg
    56641 actagatgct ggagacagcc aagaccgtca aatcttgtca ggaatcgctg aattttatcc
    56701 tgatccaagc gaattgatcg ggaaaaaagt cgtcattgta gcaaatctga aaccacgaaa
    56761 gatgcgtgga caaatcagtc aaggaatgat cctttctgca gaagcaccag atggctcttt
    56821 acaagtaatc gaagcaccaa aatccatgcc aaatggctca gaaatcgcat agaaattcaa
    56881 agggggtatg acactagttg tgtcataccc cctttttccg aaatttgaga agcaattttc
    56941 gtaaattcct tcttattact tgaagccaat catataatac agaaacagag aactatccaa
    57001 aataaatcct agaaaaagaa gtacgagctt cgctgatttt tgttaattta gaataatact
    57061 aataggaatc gtaaaaacag aaaaaaagca taatgataaa gggtcgggca gattttaatt
    57121 gattcatctg gtactctttt ttattgtcct tacattcata aagtttgaat gcaatgactt
    57181 tattacatct atatttatat ctaacagtag cgttgatgtg ttaattataa gttctatcac
    57241 tttatgttca attagtttgt gctcttatat gtgtgattga aaatatagat aaaaaaacaa
    57301 tcatcggctt tgacttcgat gattgttttc tttattttgt aaaaatccta tcacttgatt
    57361 ttatggtaac cttttatttt tgtcttcaaa cggcttggta agagagcagt aagcagtgca
    57421 aatgggatcg aaaagacata ccagaaaatc gtacgtccga taccataatg ttgatagagc
    57481 tttgtcaaca tcacgtgtaa caagatcaac cctaaaagca aggagccagc tataaaccaa
    57541 tgattatccc aatgcatgac ttcactaagt gccatcactc caaaaggata gaaataaaaa
    57601 tagatcccga ctaaggtcat ccgccagttc tttgtaaatg ttccgatatt caataaaaag
    57661 aaaatcgctg aaagcaaaat accgataggc ggaaaaagcc caaccaaaaa ggaatacaac
    57721 atcccccaca agatcatcac aggacctttg atcaatgcaa cgattgcgat gaacaaagtc
    57781 agcaatatta gtttttgtga taacgttgca acagtcatta atccaaataa aattaatgtg
    57841 aaccaatgcc aatgggactg ctgttgttct ttacgggaaa aatcgacccg gttggataaa
    57901 taatctgcta atttcggata agaacgctta aaatccataa actgttcctc cttcgtggaa
    57961 aaggtaggtt tagtatacga aaaataaaaa agaaatacat ccgtcttaag agggagtttt
    58021 tcactgaaag tggagaaaaa agaatggtaa attaaaatat tctcagttat actgaaaatt
    58081 ataccaaatt tcaaagaaga aagaggatgg gaatgaaagg caaactaaaa cgagaaatca
    58141 atctgtttgg cgcattagct accgttatgg gaaccgtgat cggtgcaggc gtcttcttca
    58201 aaactgctgc tgttactgct agtactcagt ctacaagttt gacattgcta gcttggcttt
    58261 tgggtggttt cttaacgatc tgtgctggat tgacagtggc tgaattagct acagcaatcc
    58321 cggaaactgg tggagctgta aaatatattg aagctgcgta tggaaaattg cccagctttt
    58381 tattaggatg ggcgcaaagc ttgatttact ttcctgctaa tattgctgca ttatcgatta
    58441 tctttgcgac acaattgacg aacttattac aattatctac cgattatctt ttgttgattg
    58501 cagtgatcac cgctgtttct gtgacagggt tgaatttgtt agggacaaaa gtcggtgctt
    58561 ctgtacaatc agtgacgttg attgttaaat taataccaat tgctgtgatt gtcatatggg
    58621 gattattgac cccaggacaa ggaactgtcc agttatttcc aatcgaagct ggaaaagatg
    58681 ttacttttgt cgaaggattg agcagtgcgt tgttagcaac gttgtttgct tatgacggct
    58741 ggttaggtgt cggtgcaatg gcaggggaaa tgaaacggcc ggaaaaagat ttgcctaaag
    58801 caattattct tggtttgagt tttgtaacag tcgtttatct attgatcaat tttgtttttt
    58861 tgaaaacttt gccgattgat catcttgccg gtaatttgaa tgcagcttct gaagcatcag
    58921 acgtcatttt tggaggaatc ggtggaaagc tggtcactat tgggatcttg atctcggtat
    58981 acggtgcatt gaacggttat acactaactg ggatccgcgt gccttatgcg atggctttag
    59041 aagacgagct acctttcagt aaacagctga caaagctttc aaagaagttt acggttcctt
    59101 atgttcctgc ggttttccag ttagcagtag cttgtattat gatgagcctt ggttctttcg
    59161 actttttaac agacatgttg atttttgtga tgtggctatt cagtttactg atttttatcg
    59221 gtgtctttat tttaagaaaa aaagcgccgg aattgccacg tccatataaa gtaccacttt
    59281 atccaatcgt tccgattatt gcgattctcg gtgctatttt cattttaggt atgacgatga
    59341 tgacgcaaac gaaattagca ttgatcggta taggtgttac cttgataggt atcccagtct
    59401 attatcaaaa aaagaaaaaa cgctcagaag agtaaaatat ttcaacaaca gacagaaaaa
    59461 gtacgaacta ggtcctctag atcttcgtgc tttttctatt tcaataaaac aagttcttct
    59521 attttgattt ttgctacttc tgcaagtagt gcttatgtgc taaagtaaga atgaaaagga
    59581 gagataaaca tgatatttga ttctcatacc catttaaatg ctgaacagtt caatgaagat
    59641 attccagaaa cgattcagcg agcacaagaa atgggggtaa cgaaaatggc ggtcgtgggc
    59701 ttcgatacgc caacgattga aaagtctttg caattaagcc atgactatcc aaatatatac
    59761 agtattatcg gctggcatcc gacagaggct ggcagttata cgaaagaaat cgaaaataaa
    59821 ttacaagaac aattgacttt accaaaggtt gtagcattag gggaaattgg cttggattat
    59881 cattggatgg aagacccgaa agaagtccaa gataaagtat ttcgcagaca gattgctatc
    59941 gcaaaagaaa tgaacctacc aatcagtatt catactagag aagcacttga agacacgtat
    60001 caaatcctaa aagaagaaga tgttcgagat atcggtggaa tcatgcatag tttcagtggt
    60061 gattatgaat gggcaaaacg atttcttgac ttagggatgc atatttcatt tagcggtgtc
    60121 gtcactttca aaaaagcatt agacgtccaa gaggctgcag caaatgtacc aatcgaacga
    60181 ttacttgtgg aaacagatgc cccttatctg gcaccagttc cttttagagg aaagcgaaat
    60241 gaaccaggct atactcgtta tacagtagaa aagattgctg aacttcggaa tcttccgaca
    60301 gaagaagtgg ctgcccaaac atggacaaat gcgcaccgat tatttggtct aagcgaacat
    60361 ggataagatg aagatccaag agattatagt cgttgaagga aaagacgata caagaaggct
    60421 gcgggaagta gttgatgcag atacgataga aacaataggg tctgcaatca atgaagagat
    60481 cctgatgcaa attgaacatg cccaagagac tcgtggagtg atcgttttta ccgatcctga
    60541 tttttcagga gaaaaaataa gaaaaatcat tatggaagct gttcctcagg caaaacatgc
    60601 ttttttgccg cgcacacaag ctaaaccaaa gaaaaaggga agccttggtg tcgagcatgc
    60661 aagtgatgct gctattttag aagcattgaa aaaggtcgtg acgccagaca tttcccaaac
    60721 ggctgtttct gaaatcacta gacaagacct tttagactat ggtttaatag ctggggcaca
    60781 agcaaaagaa aaacgagaaa aactaggtga cgagttgcgc atcggttaca cgaacggcaa
    60841 acaattggaa aaacgtttga agatgtttcg tattacgccg aaagaactcg cccaagcaat
    60901 gaaaatagtg gaggaacaac atgagtgaat atcgtgaaat tgcgacaccc tctagaacaa
    60961 aagagatttt attgaaacat ggtttttcat ttaaaaaaag tttaggacaa aattttctga
    61021 ctgaaccaaa tattttaagg aaaatcgtag aaactgcgca aatagatgaa catacgaacg
    61081 tgatcgaagt tggaccagga atcggtgcat tgacggaaca attagccaag catgcaaaac
    61141 aagtcgtagc atttgagatc gatgatcgtt tgatccctgt attggctgat acgatgcaac
    61201 cctatgacaa tgtgactatt gtacatcaag atattttaaa gaccgatttg tcaacagctg
    61261 ttagagaaac atttcatgag gagcttccgt taaaagtcgt agcgaattta ccttactata
    61321 ttacgacacc gatcatgatg cattttcttg aatcagattt ggttgtggat gaactagtcg
    61381 tcatgatgca aaaagaagta gctgatcgta tctctgctga accaggaacg aaagcttatg
    61441 gttcattatc gattgctgtt caatattata tggaagccag tttagcattc atcgtaccaa
    61501 aaacagtatt tgtccctcag ccaaatgtag attcagcgat tttgaaactg acaagaagag
    61561 atataccggc agtcgaagtg acagacgaaa aagcattttt ccgattgaca aaagcggcat
    61621 ttcagcaaag aagaaaaacg ctttggaata acttgcagca ttcgtatggc aaagatgacc
    61681 agacaaaagc atggttagca aaaagcttgg aaacagctgg aatcgatcca aaacgtcgtg
    61741 gggagacttt gtcattacaa gaattcgccg cattaagcaa tgcgatgtca gaaaatatgc
    61801 agtaaaaaaa gaggttgtga cagaagttgt gaaaaagctg tcctgcatca agtaataaga
    61861 acagccaaac aaaaatagtt cctcatgttt ttcgtttgtt tgggcttatt accgcagatg
    61921 caagcttttg aacaccgttt aagaaagagg ttgtgggcct gccgtttaac tctaagtcac
    61981 aaggaacaat ttcaaaaaac agcttctcat gtttttgagt tagttggtct tattacttga
    62041 tgcaagcttt tgaccactat tatgccgaac aaggagatgt gacacaaatt ttgtcacatc
    62101 tcctattttt gtttcttgat caaaaaattc ttatacttga tactcacact cattttgtat
    62161 ggatttagaa aagaatatgt gtcttgacag ttattagtaa gtgagttata ctaagtcgac
    62221 atttatgtgt caagacatat taggagagag aaaaaatgag aaaaaattca gttcgaaaac
    62281 taacgatttc tgctttattg attgggatgg gggtcattat cccaatggtc atgcctaaaa
    62341 tcatgattcc accagcttcc tttactttgg cgtctcatgt gccattattt attgcgatgt
    62401 tttttacacc aggagttgca gtggctgttg cgctaggtac gacatttggt ttctttttaa
    62461 caacgccggt tatcatcgca ttgcgagcat tgtcacatct tgtgtttgcg ttgattgggg
    62521 cttggtactt gcaaaagcat ccgagtatcg ttttaaaaaa tggacagttt acttttgcta
    62581 attggcgttt ccaagggttc aattttgtga tcggtgtgat tcattcttta gcagaaatgc
    62641 tagtagtcag catcttttac tttattggta atatgcctga aacatattat tctcaaggat
    62701 atttttatac agtattcatc ttgatgggga ttggtgggct tatccacagt ttagttgatt
    62761 ataatattgc ttattttata gcaggaacac tcagcaaata ttttgatatc cccgtattta
    62821 cggcagcaaa aaaagaaaat cggaaagagt cgattcaagg gtacgcgaag aaaacgacat
    62881 attagacatg atctctcaaa aaaaaaactc tcatctagta atggataata aatcctctaa
    62941 gatgagagtt ttttgtccta aaaagagctg caccaacatc ttctggcaca gctctaacag
    63001 ggggcaattt atggaagttt gatgacttgt tctgtttctt tatcaaagaa gtggcctttg
    63061 ctgatgttga aggcaaggtc gactatttcg cctggtttat ggaaatctct tgcatctact
    63121 tttgagatga actcagtaga accagttttt gtgtaaagca tcgtttcagc tccaagtaat
    63181 tcggaaacga caacttctga tttcactacg gcttcaggtg aagcttcaag ggctacttgt
    63241 tcactgtgga tgtcttctgg acgaataccg aagataactt cttttccttc ataacctttt
    63301 tcaactaata ctttgttttt tccttcagga atacgaagct taagcccatg tccatctgtg
    63361 ataacaccat ttttcaatgt cacattaaag aagttcatgg caggagatcc aataaagccg
    63421 gcaacgaaca tattgacggg tgtatcataa acttctttcg gtgtaccgat ttgttggata
    63481 aatccgtctt tcatgataac gattcggtca gccatagtca ttgcttctgt ctgatcgtga
    63541 gtaacataga tggtcgttgt ttcaagacgc tggtgaagtt tggcaatctc agcacgcatg
    63601 gctacacgta atttagcatc taaatttgat aatggctcat ccattaagaa gacttttgca
    63661 tcccgaacga ttgcccgtcc caatgccaca cgttggcgtt gtccaccaga taaagcagct
    63721 ggttttcgtt tcaagtattc tgtcagacct aagatctctg ctgcattgtc cacacgtttt
    63781 ttgatgtctg ctttatcata tttacgtaat ttcaagccaa aagccatatt atcaaaaaca
    63841 gtcatatgag gatacaatgc gtagttttgg aaaaccatgg caatatcacg gtctttaggt
    63901 gccacgtcat tcatgacttt tccgccgata tttagttctc cttcagagat atcttccagt
    63961 cccgcgatca ttcgcaaagt agttgacttt ccacaaccgg aaggaccaac aaaaacgata
    64021 aattcacggt ctttgattga tagattaaaa tcagttacag aataattttc tgcattgtca
    64081 tattttttat atacgttttt cagagccatt tctaccataa tacgttccac actttctttt
    64141 ttagttttat taactattta aagtataaat gaaagcgtta actaacttca atgtcatgtt
    64201 gaacaagaat tttttctttt ttttgtcaat gtgctagttt taagctttaa taaatatcca
    64261 taagaaataa aaactgatac actggagtaa ataagtatgt taacaatatc aaaaggagtg
    64321 tctcttatga aaatcgcttt gatcgctcat gaccgaaaaa aacctatgat ggtgaaatta
    64381 gcaacagcgt ataaaacaat attggaaaaa catgaacttt ttgctaccgg gacgactggg
    64441 cagaggatca cggaagcaac cggcttgccg atccatcggt ttaaatccgg accgttaggc
    64501 ggggatcagc aaattggagc catgatttcg gaggatcagt tagatttggt gatttttctt
    64561 cgagacccgc tggctgcaca gccccatgaa ccagatgtaa cagcacttat ccgtttatct
    64621 gatgtctatg agattccgtt agctacgaat atcggaacag ctgaggtgct actaagagga
    64681 ctggaagccg gcttcctaga ttttcgaaga atcgtccatg aaatagacaa gcatccactt
    64741 tcattttgat ggataagcgt atggaaaaat aacgtttaat gttcgcctat atgtagctat
    64801 aaaagctaaa caaactgata atatgcgata taatacgaac gtattggata atataaacaa
    64861 taatattagt ttttcgtatt tgcagtaaat gtgaaaatat gctatagttt ctgtgggaaa
    64921 agatcccaaa aataatacag agtagaaaat aaagcgttaa gtgctaagag gatgggatgt
    64981 tgcctcttgg acgaaggacg taatgttcgc ggttttattt tcgcattcgc tgcatgatac
    65041 gatgtagcag ctcttaaagg agatgctaaa aatgaagaaa caccggttag acgcacgtat
    65101 gattgctatt atgggcttat tgattgcatt gatggtcact ttgtcccgac tggtagcaat
    65161 cgagacccca tttattaaaa tcagtgtcac atttattcca caagtgatca tgggcattct
    65221 ttttggtcct ttttggtcag ggataggcgc agttttagct gatttagtag gaatggccct
    65281 cttctcgaaa tctgcattct ttattggatt tacattgaat gcatttattg aaggagcaat
    65341 ctacggattc tttttctatc gaaaagagat cacttggaaa aatgccattc tggctacgct
    65401 tagtgtcacg ctgatcatca acttattttt gacaccatta tggcttgcgt tgatgtacca
    65461 tgtgccattg ttcagctggg tcgtttgggc gccccgcctg ttaaaaacag taatatggtt
    65521 accgattcaa tcaattgcca tttattacgt aggacgtagt attccttaca aaaaaatttt
    65581 aagaagttta gcgatccacg ctaaataaaa aacaagcagt cttcccatcc cagaagactg
    65641 cttgttttta ttgtgctgtg aattgtgctt gatagagccg tcggtaataa ccatcttttt
    65701 gaagcagctc atcatgggtg cccatttcga caatagctcc ctgatccatc actaatatct
    65761 ggtccgcatt tttgattgtg gacaggcgat gggcaatcac aaaactggtt tttccttcca
    65821 tcattgctaa gaaggcttgt tggatttttt tctctgtcaa tgtatcgact gagctggtag
    65881 cttcatctaa gatcaacata gggggattac tgatcatcgt tcgagcaatc gtcaacagtt
    65941 ggcgttgtcc atctgatatc tttaaccctt gaccgccaat cttagtatct aatttttccg
    66001 gcaaacgttc tacaaattca tacatataag aggcttttag ggcatcattg atttctgcgt
    66061 cacttgcttc cggattccca aaacgaagat tttctcgcaa tgtactgtca aatagccaag
    66121 tatcttgtaa caccattcca aaacttttac gtaatgtatc acgttggata gagcggatgt
    66181 catggtcatc gactgtaatt gttccttttg ttgtgtcata aaaacgcatc agcaaattaa
    66241 caagtgtgga ttttccggcc cctgtttttc ctactatagc aatggtttga cctggataag
    66301 cagtaaaatt gaaatcttcg atcaaacgct gcttggggtc ataagaaaaa gaaacatgat
    66361 caaaagagac ttttcctttg atatttttgg gttccaaggc ataggcatct ggcaaatcag
    66421 gcttttcttc tggctgatcg atcaaatcaa atgctcgttc tagaccagaa aaagcggttt
    66481 gcagttgtgt cgtgattcca gaaagttcga taaatggttt agaaaactga cttgagtaga
    66541 tcgtaaagct ggaaatcaca ccaacagtga ttgacgaacc actcttcaat gccaataggc
    66601 cgccaactaa accaatcgat aaataagcaa ggtgatctac aaaacgagaa gacgggtttg
    66661 tcaaggaaga agaaaattgt gcccgttgtc ctttttcata tagatcagca tttagcagtt
    66721 caaattgctg ttgactagct tcttcttgct gaaaagcttt cacgattttc tggttaccga
    66781 ttcgttcggt cacaaagccc gagatatccc caataatcct ttgctgtcta tcgaaatttg
    66841 tttgtgaagc acgagcaacg atccaactca caaggaaaat aattggtgta gaacaaagaa
    66901 cgaccaatgt cagaagtgga cttagacgca tcataaaaat aaacgaaaga atgatgattg
    66961 ccactccaga aaataattga ttgaaggccg cagaaattgc aatggaaata ttgtccatat
    67021 catttgtaaa tcgactgacg atatttccgt gggagttttg atcataataa cgaagtggca
    67081 atcgattcag atgagcaaat gcatcttttc ttaattttgc aacggataag taagctaacc
    67141 gattgcttaa cacttggatg agccattgac tgactacgtt gattaaaacg ataccaccga
    67201 atagaataag taaatggaac agtcgattga agcggacctg tccttctcca atcatttgat
    67261 cgatactttg accaatttgt aacgtcatca caactgttgc aatcccattg atgattccta
    67321 gtatcacagc tagccaaatg tcttttgcat aggcagtaag gtaaggaatg aatcggcgga
    67381 gcgtctgcaa ggataatttt tttactttca taactattct tcctcctgtg atgcgacgat
    67441 ttcctgatat tctgctgatt gagcaagtaa ttcttcatgg gtaccctgag cagcaatctt
    67501 accttgatcc atcactaaga tatgatgtgc ttcttgaata gagcggacac gttgggagat
    67561 aataatcact gtactgccaa gataagtctg tagcgcctta cgcaaatcca agtctgtttg
    67621 ataatccaac gcacttaaag agtcatctaa aatcagtaat gctggcttgg caatcaaagc
    67681 tcttgcaatc gtcagtcgct gtttttgtcc gccagagaaa tttttcccat tttccatgac
    67741 ttttgtatct aaaccatttg gaagctgacg gacaaattct tctgcctgag cgattttcag
    67801 agcttcccaa cattcttttt ctgtggcgtc tttcttaccc cattgaaggt tttcacgaat
    67861 agtcccggta aatagtacag aagtttgggg aacaagagca atttgctgac ggagatgatc
    67921 cagctgccaa gaacgaacat ccattccgtc cattataact gtaccggaac tgacatcata
    67981 gaaacgcgga atcaattgtg tcaaagtcgt tttcccgctt ccggttggac caatgattcc
    68041 aaggactgta tttcgcttca gctgaaatgt aatattttgg agagaaagac cagaatcagg
    68101 agtataacgg aagtcaacat ggtcaaaagc gataattgct tcagaagaaa aatcgggagt
    68161 agtactgacc tcagcttcaa gaatcgaatt ttctgtgtct agcacctctt tcacccgatt
    68221 tcctgaagct tcggcacgtg tgaagatcac gacgaggttt gaaacaacga tcagtgccaa
    68281 aagcatttga ttcatataat tgatcaaagc aagaacttgt ccttgttgca agctaccaat
    68341 atttactttg atcccgccaa ctgtcagcaa acagatgatc ccgacattca tgatcaaggt
    68401 tgtagcaggt gataataggg cagagatatt ggaaacacgt aaataattgt tcgctagatc
    68461 atttgtgctt ttatcgaact tctctgtttc tttttttgtc tgcgcaaatg cgcggatgac
    68521 acgaacaccg ctaagattct gactaacgtg ttcattgagc tgatctagtt tttcttgcac
    68581 tttttggtag agaggaacgg tttttttgat gataaaaaat aaaatgattg agaaaatagg
    68641 caataatgct aagaaaaaca gacctacttc ccagtcgatc acaaaagcca tgaccactga
    68701 cccgatactt aaaaacggtg ctctgatcaa taaacgaatg accattgcta aagctagctg
    68761 aagctgattg atgtcgtttg tcattcgggt gatcaaggta tctgttccaa aatgattcaa
    68821 ctcgttgtga gagaaagtat tgattttttt gattagctga ttacgtaact ctgtaccaaa
    68881 tccttgtgaa gctactgaag catagtattg gcaaatgata gcacaaatca gaccaatcac
    68941 agacatagcg accatccata agcccatttc aatgattttt cctcggtcat tcatttttag
    69001 tccattatcg atcaaggaag ccatcattaa aggcaggaca agttcgaaga cagcttcaag
    69061 aaatttgaag aacgggccca aaatgatttg cttacgatag tcttttgcat aacgtaataa
    69121 ctgaatcata tgattcctcc tattatttat ttgtccacaa ttgaaaaaac aagtactacc
    69181 acattgtagc ttaggaaatt tagaatgaaa agagaacaag ccttttcata aatgaaagtt
    69241 ttattatgaa gaagctttag aaattgaata gactattttt tttaaaaaaa agaaaatgag
    69301 aaaacatgcc agtctcttca ttcataggaa cgtctatttt acttaatttt tctataaatg
    69361 aattctgcat aaaaaatata tcaagtaaat gtttatagat gaaactctat ttacttcttt
    69421 tttaatttgt tcttgcaatc ttttttgcta cgtaattttt gtaaaaaagt gggttgagag
    69481 aaatctaatt gattttcaaa gaaggagtat gaaaatgaga aaaatattta ttcgtttatt
    69541 gtgggtacta tcttagagga ataaataata gtggagaaaa ctatggtttg gcgcagattc
    69601 tatcaggttt gatggaacga agacaacctc ccgacatcaa gtcaaaagcc acttgagatt
    69661 ttgatctgaa aataaaaaaa gaaaacaagg taggaacatc aatgtttcta ccttgttttc
    69721 gtaatcaatg ggaaaaaact aagagtggtg tacgtaatca ataaaaagga tggtgacaac
    69781 agtacctctt tactctctga aagcatcata actcgttttt cctcattatg ccaataaatt
    69841 gttgttatac cacatataag gatttgtaat agctaaaaac agacaggaaa gttgaaatct
    69901 gtgaatctta ttttgtatgg aaggatttat agaacgcaaa aatcaagata aagatgaata
    69961 aaaatcctgt ttcggctata tattgcgtat ctacgccaat aaaacgagtt tgttctgtca
    70021 tagccatata aagcaaaggc aaaaatacaa ctacagcgag ataagatccg atgatttctc
    70081 gaaaagtttt ccaggaagta tgtttcctgt ttttatattt atccgatttc attgaatagt
    70141 catagcctcc ttattctttc atatgttgaa attccagtat aaaaactgga aggaactgta
    70201 cgttttttag aataaaaatt ataagggata agtaggctgc tgtctataat aagatatatt
    70261 tttcaattct ttattaaaga ttttattgac aaaatgaatc cgttttctat gatggaggag
    70321 gggtgaataa gttgttgaag aaggaaattt tatgttactt agagaaccag acagcctttt
    70381 tcgatttaga acatatgaac gaggtcttta cagcacaaag gttagctgat cattttgggg
    70441 taaaaagaaa cacagtcagt cattatttga accagttaaa tgatgagcaa ctactagtca
    70501 aaatcaattc tcgaccagtg atttatttcc acaaagaagc ttttgaaaaa caatttttta
    70561 agttacgcac gaatttttat ttttctatcg atgatctcaa agaggaacag ccttttttcg
    70621 cgcaaccaaa agacttattc tcttttatga tcggatacga cgccagtttg aaagaaagta
    70681 tcgaacaaat caaaacagct ctttactatc cagatggcgg attaccactt ttgattacag
    70741 gcgaaagtgg cacaggtaaa agttatttag ttaatttggt ctatcagtat tgtctgcttc
    70801 atgatctgct agaagattct gcaccattca tcacttttaa ttgtgcacaa tatgcagata
    70861 atcctgaact tttgactagc aatttgtttg gacatgttaa gggagcgtac actggtgcag
    70921 aagaaaataa aaaaggggct tttgaagcag cagatggtgg gatcttgttt ttagacgagg
    70981 tacatcgctt aacaccagaa ggtcaggaaa aactgttcac ctatcttgat caaggtgtga
    71041 tttatcgtat gggagaacct aatttgtcac gccggatcaa aacacgtctc ttttttgcta
    71101 cgactgaaga gattactagt catttcttaa caactttcat tcgaagaata cctatccgaa
    71161 tcgaactacc tgcacttaat cagcgtagtc gtaatgaacg gctagaactg atttactctt
    71221 tttttctcga agaacaaaga aaaatgggga gccctttgtc agtcagtgga ccagctttgt
    71281 cacttttaac aagtcagaaa ttatccggaa acataggaga gctgaaaaat atcgtcaaag
    71341 tttcagcagc aaaagcatat gctgaacagc gtgaacagcc tgaaatccat gtcacgatcc
    71401 atcatttgca aaaagaacta cttgcgcagc ctattactaa aaatacagca cagcaaggaa
    71461 tctatattac gcaagaccag accttagagc aattaatgga gaagcaacag cccgaacagc
    71521 agcgaatcgt taaaagtttt gagcaaatcc taattgattt caagaaaaat aactgtctgc
    71581 tatattcttg cgaaggaaaa ttaaagcaag aagtgattca attatttgat tttttgctgt
    71641 ttgagaccag tagacaagaa aaacacgagc tgctggttta ttggacacaa tctatccgag
    71701 agacctttcg acaaatggaa actgcctatc aaatcaaatt cgatggaaac agtgtctatg
    71761 ccttgagtta ctatctctat cagcgaagca ctatcaaatg gttaccggaa gaacatgata
    71821 ttatccaact aatcaaagaa ttagaacaac aagtttctca gtcttatcca tctagttatc
    71881 actatgtcca acgaattctg gaattaagta agatcaaatt agatattgaa gacacaagta
    71941 tggatcggat tttactgacg atctatctaa aaaaagcgaa atggtcaaaa gaaaaacgac
    72001 tgccaaaagc gatgattgct gctcacggtt atgcaactgc tagcagtatg gcaaatgtag
    72061 taaatcgttt attacaagag gatctatttg aatcatttga tatgccacta gatgtcacac
    72121 cacagcagat tgcttcagaa atccttgatt attgcgaaaa cagcgatgtt tcaaatggat
    72181 tgatcatatt agtagacatg ggatctctga aagaaatcca tcagtttttt aaaaaacagt
    72241 tatccgtacc gcttttgatt ttgaataatg tgacgacacc tttagcaatc acagtagggg
    72301 aatgcctgca aaaaaatgta tcattagaag agatagcaga agagactgtt cgacagatcc
    72361 agccagaatg gcgactgctc tatccagagg aaaacaaacc caaagcactc attactactt
    72421 gcttcactgg aatcggtacg gcggtccact taagtgaact gctagaaaaa agcttaccta
    72481 cggcttgtca gttgaaaatc atcccatatg aatatcagca attaaaagat aagaaaaaca
    72541 gtgacccatt attttccata tacgaagtcg taggaatgat tggcaccaca gatcctgata
    72601 tcaccaatat cgactatctt tcattagaag acctcatctc gggggaaaag atgtctgtac
    72661 tagctgaatg gttggacact actatgaatg cttcagagaa ggaaatattc aatcagcgca
    72721 tcattcgtaa tttttcattg gaaaaagtac tggattccgt gactattcta gatacagaga
    72781 aggtgatggg agaaatcgat cattttatga gagaattaga ggtgcagttg aatcgaagca
    72841 tcagcaatcc caaaaaatta gcgttgtatg tccatgtgag ctgtctcatt gaacgattga
    72901 tccgacaaat gccaatcgaa acctatcaag gattagagaa atggaagcag tgtcaaaaag
    72961 aagggttatc tgctattaaa tctgcgttta gtgtcattga agagcattat agtgtcatga
    73021 tccccaattc tgagattgcc tatatctatg atattttgag tgaagataca gagtttctct
    73081 cgatagaaga agaattttga acataagcaa gttgttgcca ctaattttgg catgcaactt
    73141 gcttttttag tatgtgtaag tgaaaagagg agatgaaaaa gtggatagag aaattatctt
    73201 agcttcccat ggaaaatttg cttcagggat attagattca ttagagctga tctatgggaa
    73261 aaatcattct attactgtat tcgattgcta tactgatgag aattttgatt tagcggaaac
    73321 agtaaggcag ctttttatga ggtacaaaga taaagaaatc attgttctga cggatctttt
    73381 tggcggaagt gtcaacaacg aattcttaca atatatcaat cgggatcatg tctatctcgt
    73441 tgccggattg aatttgccac tattgattga gctagtatct cggttggacg ctgaagtaga
    73501 gacaactgtt ttgatccagc aggtgctaac tgattcaaaa aaaatgatcc agttttgtaa
    73561 cgagcggctc aatcagaaaa tagaagaaga cgaattttag gaggaagaaa aatgattgta
    73621 ttgacaagag tcgaccatcg gttattacac ggacaagtag ctttttcatg gacacaaaca
    73681 ataggcgcag actgtatttt gattgctaat gatgatgtac ctacgaatga gatacgaaag
    73741 acaacgatca aattagccaa gccacaagga gtcaaactag tgatcaaatc aattgatgac
    73801 tcgattgccg cgttgaaaag cggggtgaca gataaatata agttattcat cgtagtggaa
    73861 tcgatcgagg atgcatataa gctggcagaa gcgtatccag aaatcaaaac catcaactta
    73921 ggagggatca aggcaaaacc tggtactcgc agcatcggaa aagcggtaaa tattttacca
    73981 gaagaggagg aacgcttgaa acgattaatt gacaaacaaa tagaagtaga aatccgtcaa
    74041 gtaccagcag ataaaaaagt ggatgtaaga gaagttttgt aagaaaggaa gaacctcaat
    74101 gattgtacaa gcagtcttat taggaattgt tgcatttgtc gcacaatcag aatatgcact
    74161 agggacatcg ttgctttctc gtccgattgt gacggggctg tttacaggaa tcgtgttagg
    74221 tgatgtaaaa actgggatca ttatgggcgc aactttagag ttagcattta tcggatcgtt
    74281 ctcagtaggt gcttcgattc cacctgatgt tgtgaccggt gggattttag ggacggcttt
    74341 tgctattaca gctggagccg gtacagaaac cgcgctttta ctaggtttgc cgattgctac
    74401 gttgacattg atattgaaaa atatttactt agggcttttg attccaatta tgaaccataa
    74461 agcagacaat tatgcagaag aaggaaatta taaaggagtc gagcatatgc acttgcttgc
    74521 cggtatcggt ctttccttga tgcttggtgt tgtggtaatg gtttcttata tggtgggaag
    74581 caatacgatc ggaaatctat taaatatgat tcctgacttc gttcaaaagg ggttgtcagt
    74641 agctacaggg ttgattccag ctcttggttt tgcgatgctt gctcgtttgc tgatcaacaa
    74701 acaagttgca ccatattttt tcttaggttt tgctatagct tcttacttag agattcctgt
    74761 gaccggagta gctatttttg gtgcgatttt agcagttgtg gtagtcaata ttatgaatgt
    74821 ccgtcaacta ccacttcaaa caactgcagg ggaggtagaa gaagatgaag aattctgaga
    74881 tcaaaaacag caaaataacg aaaaaagagc taaatcacgt attttggcgt tcttttcaaa
    74941 tggagttttc ttggaattat gaacgtcaga tgaatatggc ttatgtttat gcaatgattc
    75001 cgattttgaa aaagttatat cagtcgaaag aagaaatggc agcagctttg aaacggcatc
    75061 tagagttttt taacacgacc ccacatatcg ttacactgat tttaggaatc acggctgcaa
    75121 tggaggaaga aaataaggat gatcctgaat ttgatgtgac tgcgatcgat agtatcaaaa
    75181 catctttgat gggacctctt gcagggttag gagattcttt cttttgggga actttgcgat
    75241 tgattgccac aggtgtgggt acctctttag ccatgcaagg aaatatttta ggccctatct
    75301 tgttcatttt gattttcaat attccgcaca ttctgtttcg ctatctagca acaggttggg
    75361 gatatcgctt aggaacgggt tttttgaaaa agatccaggc aaacggtatg atggaaagtt
    75421 tgacattagg cgcgtctatt attggactga tggtcgttgg agcaatgact gccacgatga
    75481 tcaccatcaa tattccttta aaaatcggtt caggagaaaa tgctgtgact gttcaaagta
    75541 tttttgatga tatcgttcca aatatcttat gtcttggagc atttggcata gtgttttatc
    75601 tattgaagaa agaagtgaaa ccattaacga tcttgatcgg actagctttc tttggaattt
    75661 ttggttcgtg gatagggatt ttttaaaaaa ggagcagaga aaatgtttac gatgcaagat
    75721 tatatctatg aagaaaagga agtactaagt acgatcttga aaaagaatga tttttcgaca
    75781 agagaacata tgaaaaaaac agtgaattta ctgatcttag caacgggttc atcttataac
    75841 gcttgtttag cagcgaagcc agcattggaa tcttatggtg atcttactgt cgatattcaa
    75901 gaaccttttt attttttcaa ttatggaaaa ctttctcctt caatcgatac tgtgattgct
    75961 gtgtcacaaa gcgggaaaag tgcttctact gttgaagcag taaaaatgat acaaaaacaa
    76021 gggttacctg ttgttgctat cacaaatgac gtgcaaagtc cacttgcttt agaagctgca
    76081 caaattattg atttaggtgc cggggtagaa tcagtaggct tcgttacaaa aggctattct
    76141 gcgactgttt tacagttact actcttaggg ataggaattg gaataagtaa aaataaaatc
    76201 agcaaaaaaa tagaacaaga ctacatgcaa cagttgcgca aaataatcaa ccatttacca
    76261 gcgattattc aaaaaacgga agaatttttt gatggatatc aaagtttatt tcgtttagca
    76321 cagcgtttcg tcaccattgg atatggtcca aactggggaa cagctaaaga agcagagacg
    76381 aaattgactg aaacaatccg cgttccgtca caaggatttg agttagaagc ttatatgcac
    76441 ggcccatacc tggaggcaga tgcttcgcat ttgctattct ttattgaagg ggaaagtgta
    76501 aataaggaac gttcgcaaaa gttgcaaaga tatatgagtc ggtacgttgg agagactctc
    76561 accattacca caaaaaaagc aagaaacgag aaaacacttg gattagcaat agaatgtgat
    76621 gaatatctgt ctgtattagc gcttgtcgtt ccgtttcaac tattcgctta taaaaccgca
    76681 gtagctaaag gtattgactt gaacaaaaag atttttgaag actttgatac agtcttgaaa
    76741 agtaaattat aagaggtgga aatcatgctg aaattcaatg aagaagaaca aatcaaagca
    76801 ataaaaggcg cactagcttt acgtccgcaa gtagaagaaa tcatcgataa actttatgcg
    76861 gaaaaatttg acgctgtcta ttatctagga atcggtggaa cgtatgcttc ctcgatgcaa
    76921 gctgtcactt atatgaatgg gaaaagcaac ttgcctgtct ttgtacagca tgctgcagaa
    76981 tattacacta ctggaaacaa aagattaaca aaagattcta tcgttatttt gtcctctgtt
    77041 accggtacaa ctcaagaagt agtgaaagca gtagaacaaa tcaagaaagt aggagcgaca
    77101 ctgattggat ttatcgataa agcgaacagt aagttgtctc agctatgcga ttttgtggtc
    77161 acttatccag ctcctggaac agaacaaatc aaatttttta tggcagcaga tcgattgatg
    77221 tatttgaatg gagaattcga agcttattca gaatactatg aacagctcga acgttattta
    77281 ccaacagggt tagtggaagc agagaaaaaa gcagatgcat ttggcttatc atttgcagaa
    77341 aaacatcgac gtgatagtat gcattatttt attggagcag ggaatcaatg gggagctgtt
    77401 tattcatatg ccatgtgtta ctgggaagaa caaagctggc ttccatcgaa atctatccat
    77461 gctgccgagt ttcttcacgg gacgttagag atcgtagaag aaacaacccc agtcacatta
    77521 tttttaggcg aagatgaaca gagagtgtta tctgaacgtg tggctaaact tttgccaaaa
    77581 atttgcagca attatacatt gatagacaca aaagactatc cagtagaagg tatcagtgaa
    77641 aaatatcgcg gacgtgtttt gtctttctta ttgatgcatg tagtgacaca acgcatcgat
    77701 gctcatgtgg agcagttgaa ctgccatcca ttagagatac gccgctacta tcgtcagttt
    77761 gattattagg atagactgga taaaaagaat ataaaaaata aagagagcag cgataactgc
    77821 tccctttatt tttttaaaat attggcatca attacgttat aaaacacatt ttttgcatta
    77881 tctacagttc aacttataat ctgtttaatg ggacatgtgg gtgccaacca ttttttgtta
    77941 tgcaatagta ctatttagtt gttgcatgga tccgtagtaa aagtccaagt acaacgagtt
    78001 gcgccagttt acatagcgtt ttgtatccag aatgttgact aaaacaaaag ttcctatgtc
    78061 aaccgtcaac agagacaatc tgtccgttgc aggacctgac agatttagaa atgttcaatc
    78121 tgtctcttat gtattttaaa tcaatactca ctaggagaag tttcctaacc tcctaatagt
    78181 aatgctggta gtaacattgt caaaactgct tcctcttagg aacaagcaaa gcataacgag
    78241 tgtaaaaata aaatgtagac tattgtaaca tatcattgat tatttcaagt aaaaacgata
    78301 aaagaagtaa acaaacactt aaaaacaatg gaaattagtc ccaactttaa gaaatgtata
    78361 ctataatgga aattatcaat tatttatttg gaggaatatc catgaaacaa aaaatcgcag
    78421 ttcttggtcc tggatcttgg ggcactgctt tagcacaaac attggcagaa aacgggcatg
    78481 atgtccgtat ttggggaaat gtacctgaac agattgatga aatcaataag tatcatacaa
    78541 atcagcattt tttacctgat ttgacgatcc cagaatcgat tatcggatat aaagaattgg
    78601 cagaagcagt ggataacgca gatgctattt tatttgttgt tccaacaaaa gcgattcgtt
    78661 cagtcgcaca ggaacttatt ggtaaaatga atactaagcc aatcattata catgcaagta
    78721 aaggactaga acaagatacg cataaacgaa tctcagaagt tttggctgaa gaaattccag
    78781 aagaaaaaag acaggcaatt gttgtattat ctggtcctag ccatgctgag gaagtggcag
    78841 tacatgatat cacaacaatt acagctgcaa gtattgatca aaaagcagca gcctatgtac
    78901 aaaaactgtt catgaatgat tatttcagga tttatacaaa taatgatgtg attggcgtag
    78961 aaactggtgc agcactgaaa aatatcattg caattggtgc cggcgctatc catggattag
    79021 gattcggaga tgatgcaaaa gcagcaatca tgactcgagg attggcagaa atcagccgtc
    79081 ttggtgtcgc gatgggtgcc aatcctctga catttatcgg tttgagtggt gtgggggact
    79141 tgatcgttac ttgtacaagt gttcattctc gcaattggcg tgccggtaac ttgttaggac
    79201 agggacataa gctggaagaa gttctagaaa acatgggaat ggtcgttgag ggtgtggcaa
    79261 cgacaaaagc agcagtagag ctagctcaac agctaggtgt tgagatgcca attactcaaa
    79321 caatctataa tgttttgtat aatggagaag atatcaaaaa agcagcaaaa gaaatcatgt
    79381 tacgtgacgg aaaaatggag aatgaatttt ctcttcgtta aatagatgat caatagttaa
    79441 tcgtcgttta ggaggaacag caagtgaagg tcaaaaaagc agtcattcct gccgctgggc
    79501 taggaacacg ttttttgccg gcaacaaaag ccatggcaaa agaaatgctt ccaatcgtgg
    79561 ataaaccaac gatccagttt attgtggaag aagcattgga ttcgggaatc gaagacatct
    79621 tgatcgtaac gggaaaagaa aaaagaccca ttgaagatca ctttgatgca aatatcgaat
    79681 tggaaaacaa tttgcgggaa aaggaaaaaa cagaattact cgctttagtt gaagaaacga
    79741 ctcaagtcaa tcttcacttc atccgtcaat ctcatccaag aggactgggg gatgccgtgc
    79801 ttcaagcaaa agcatttata ggaaatgaac cgtttgtcgt catgctgggg gatgatttga
    79861 tgaaagatga tatcccattg actcaacaat tgatgatgga ttatgaagaa acacaagctt
    79921 ccgctgttgc cgtcatgcgt gtaccagaaa atgaaacatc taaatacgga attattgatc
    79981 ctaaaacaga tagcgaaaag ggtcgttgca gagtaaaagg gtttgtagaa aaacctgaaa
    80041 tgggaaaagc accaagtaat ttagccatta tcggacgtta tctactgact cctaaaatat
    80101 ttgagatatt agaaactcaa gaaccaggag caggaaacga gatacagcta acggatgcac
    80161 ttcagactct taaccagaca gaggcggtct atgcgagaga gtttaaagga aaaagatacg
    80221 acgtaggcga taagttagga tatatgaaga caaatattga atatggactt caacattcgg
    80281 aaattgggac ttcattaagt gcatatatta tccagttgag taaaaagcta agaacagaaa
    80341 gttaactgga aataagtggc ctgctgagaa tgaaaggcta tttgttatta aagcggcagc
    80401 ttgtgcgtca tttgcgcaac tgtcgtttta gttttttgac tctagatcag ttgagtcgtg
    80461 gaaaacgaaa gatagaaaaa gactttcgtg aatagattca gaaaatatta tgctaatggt
    80521 ttaatttttt tttaagttgt ataaaagaaa atgattacat aagagaaatg aaagccaagc
    80581 cagaagattc atagtagaat aaaaaggcga attttttaat tataaaaaaa ggtgtgtgtt
    80641 cactatggga aaattagtcg ctgttgcaca gtcgctgctt gatatactca agtggctgat
    80701 ggaaggaagc aattggatat ttgtgttgcc actattgctt attagtctat ttatcatgtt
    80761 tcgcatggtc agaaaaaaag aaacgtttct gatttttatc tggtatgcag catccgttgg
    80821 ggttgctacc ttgatggttg aattggcgtt aggtagttgg gaagcttgcg tatttgcttt
    80881 attttttgct gtactgtatc taatcattta tatcccatat atgaaaagaa agtctcggat
    80941 aggcagaaaa ggtagacata caactacttt ttctagtaca gattctctcg aacaaagtag
    81001 aagaacgaga agaagacggt aatatttagt aggtatacgc aaaaaaagat aaaataatgg
    81061 ataaactatt gagatgagag atttatttaa ttggtggaaa aaagcttttt tcacttatat
    81121 aaaagaatct tttttaaagg aatgcttgtt gtatcgggat aagccattcc tttttttatg
    81181 ttatttatat atatataaat cataccaatg tttttttgta ttttcttgct tgcacttgga
    81241 taagagatta cttacaataa attcagatag aaacagctga ataaaaaaag gctccctgac
    81301 ccttagttgg cgctaagaat cagggaatga ccagtcacac acatacaccc tgaccgatca
    81361 ttttgccata gtcaatgcag tgcatcgacc taatttattg tacctaatct agggtgaaaa
    81421 ttctacccct atgtagatat tttccatggt ctgcacgttg ttttatttgc tatgtcaagg
    81481 tattgggcgt attcgttcaa tgcctttttt gtgtttgaaa cagcaaagac cacatgtgtt
    81541 actgtctaac tactgttttt ttatgtactt ccttagatta ggcagctgtt tctattcatg
    81601 tcaagtatag ctaggcggga gagataaatg agtttatgtt attttgacta ttatcaccaa
    81661 ttggaagaga aattaaggat agaagagccg ctgatgcttc aagctggcac ttggatcgcg
    81721 aaacaaatta atcaaggtgg tagattgcag atatatgcta gccgcacact aagtggtgta
    81781 gcatttgaat tttgggatca aaccccggat cttgtaccaa gtatattgat tgaaaatcca
    81841 gccggaggtg tctatgaaac gctagaaggt gcaggacagg caattattga tcagctttct
    81901 gtcaaatcag aagacatttt tcttcttctt tcgaatgaag gaagaaaccc ggcaatcatc
    81961 gaactagctc agtggatcaa agaaaatggt catccattaa tcattgttac tggatttgat
    82021 ttgtcacgaa gtatcaaatc gcaacatagc agtggtttgc gattatttga atttgctgat
    82081 ttggttttgg acaaccacgc caatttacat gatgcagtct tgactttgcc aaatctagat
    82141 ccagcgatct gcggaacagc ctctcttgca acgatctttt tgctgcagca agttttgtat
    82201 tttacagcaa aacagctagt ccaggacaca agtggaaaat agttatccac atgttgacaa
    82261 agttccttaa aaaaataatg ttccacataa aaatggagcg tttgaaaaaa agaaaacgat
    82321 tattaatgag gattaacaac gactactttt tttgttttag ttattttaag atggatcatc
    82381 tttgatttta agcttgtttt gtttaaagtt tgttattttt ataagttgtt tcacagttat
    82441 gagaaatgag ttataagaat atgtagtgtc agaaaaataa aaagtagtgg aaaaagagac
    82501 aagaaagaat ccatatggat tctttcttgt ctcttaatac acgttgatga aagagtcttc
    82561 cccaaaactc tttacaaagt aattatagta catttgttat cattattgca atgaagttta
    82621 cctgatataa caaaattgtc caacaggata cctttttcta atagaaataa aatacacaaa
    82681 aattgaagga tagataatgg atatttataa gtgtttatta ttttttttgc aatgaaattc
    82741 aatttttcaa tgattgtaaa atgaaaaaaa caggacgaga ttttctctaa tctaaaaata
    82801 aaaaaagaat tttaaggaa
//
LOCUS       DADQDV010000004        81100 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.004, whole genome shotgun sequence.
ACCESSION   DADQDV010000004 DADQDV010000000
VERSION     DADQDV010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 81100)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 81100)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..81100
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.004"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(50..985)
                     /gene="whiA"
                     /locus_tag="J8S10_000246"
     CDS             complement(50..985)
                     /gene="whiA"
                     /locus_tag="J8S10_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HAZ9628862.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            complement(1019..2017)
                     /locus_tag="J8S10_000247"
     CDS             complement(1019..2017)
                     /locus_tag="J8S10_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HAZ9628863.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAINR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            complement(2014..2898)
                     /gene="rapZ"
                     /locus_tag="J8S10_000248"
     CDS             complement(2014..2898)
                     /gene="rapZ"
                     /locus_tag="J8S10_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HAZ9628864.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            complement(3033..3764)
                     /locus_tag="J8S10_000249"
     CDS             complement(3033..3764)
                     /locus_tag="J8S10_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HAZ9628865.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLRPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTALQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSEALDTASEK"
     gene            complement(3768..5033)
                     /locus_tag="J8S10_000250"
     CDS             complement(3768..5033)
                     /locus_tag="J8S10_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HAZ9628866.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            complement(5296..8112)
                     /gene="uvrA"
                     /locus_tag="J8S10_000251"
     CDS             complement(5296..8112)
                     /gene="uvrA"
                     /locus_tag="J8S10_000251"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HAZ9628867.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQEIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            complement(8122..10116)
                     /gene="uvrB"
                     /locus_tag="J8S10_000252"
     CDS             complement(8122..10116)
                     /gene="uvrB"
                     /locus_tag="J8S10_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HAZ9628868.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQIRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKDAAKALDFETAANVRDMILELKASK"
     gene            10375..11877
                     /locus_tag="J8S10_000253"
     CDS             10375..11877
                     /locus_tag="J8S10_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAZ9628869.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            11879..12616
                     /locus_tag="J8S10_000254"
     CDS             11879..12616
                     /locus_tag="J8S10_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAZ9628870.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(12661..12834)
                     /locus_tag="J8S10_000255"
     CDS             complement(12661..12834)
                     /locus_tag="J8S10_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAZ9628871.1"
                     /translation="MEKKNQAQLSEGGIDYVLDIINEPMVLSYAMEQVERLLVCAGKQ
                     AMRLIRLGEKIRR"
     gene            12810..13475
                     /locus_tag="J8S10_000256"
     CDS             12810..13475
                     /locus_tag="J8S10_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar diacid utilization regulator"
                     /protein_id="HAZ9628872.1"
                     /translation="MELDFSSPYYVVVGQLSDNQQLCQERINPLLELLERVFSYYGQA
                     LLTVHRQQIIILVNRISRASLLSLLDKIQTKFNKMYQLQLNFGIGSLCYTEQETPQSF
                     LHAKQVCEWIAFHQSVNEIRFFEDLDLGIVLPAIPSDQRTLYVKRILKSLTEEEVHLF
                     KKTLACFSKNNGSIKNCSEELFIHKNTLQYRLNKFHSLTGYTPRNYDDYHILKLAFLL
                     VQT"
     gene            complement(13557..14723)
                     /gene="dnaJ"
                     /locus_tag="J8S10_000257"
     CDS             complement(13557..14723)
                     /gene="dnaJ"
                     /locus_tag="J8S10_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HAZ9628873.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(14874..16703)
                     /gene="dnaK"
                     /locus_tag="J8S10_000258"
     CDS             complement(14874..16703)
                     /gene="dnaK"
                     /locus_tag="J8S10_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HAZ9628874.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            complement(16754..17317)
                     /gene="grpE"
                     /locus_tag="J8S10_000259"
     CDS             complement(16754..17317)
                     /gene="grpE"
                     /locus_tag="J8S10_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HAZ9628875.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            complement(17411..18454)
                     /gene="hrcA"
                     /locus_tag="J8S10_000260"
     CDS             complement(17411..18454)
                     /gene="hrcA"
                     /locus_tag="J8S10_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HAZ9628876.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEDKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            complement(18688..19854)
                     /locus_tag="J8S10_000261"
     CDS             complement(18688..19854)
                     /locus_tag="J8S10_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HAZ9628877.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMKIMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYLDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNAHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            complement(19870..20097)
                     /locus_tag="J8S10_000262"
     CDS             complement(19870..20097)
                     /locus_tag="J8S10_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HAZ9628878.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            20581..21171
                     /locus_tag="J8S10_000263"
     CDS             20581..21171
                     /locus_tag="J8S10_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HAZ9628879.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQNEKWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKTIRLYKLGFYDYYKKYGDPFS"
     gene            21361..22074
                     /locus_tag="J8S10_000264"
     CDS             21361..22074
                     /locus_tag="J8S10_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9628880.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLIDVTVIDN"
     gene            complement(22189..23199)
                     /locus_tag="J8S10_000265"
     CDS             complement(22189..23199)
                     /locus_tag="J8S10_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HAZ9628881.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPTWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQSSEKYQKVWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTIRHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(23236..23718)
                     /locus_tag="J8S10_000266"
     CDS             complement(23236..23718)
                     /locus_tag="J8S10_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HAZ9628882.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            23868..24236
                     /locus_tag="J8S10_000267"
     CDS             23868..24236
                     /locus_tag="J8S10_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chaperone"
                     /protein_id="HAZ9628883.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            24701..25153
                     /locus_tag="J8S10_000268"
     CDS             24701..25153
                     /locus_tag="J8S10_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAZ9628884.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQFREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNYVVNFSQWINEKLLIQTDISLVS"
     gene            complement(25277..26128)
                     /locus_tag="J8S10_000269"
     CDS             complement(25277..26128)
                     /locus_tag="J8S10_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HAZ9628885.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(26141..26926)
                     /locus_tag="J8S10_000270"
     CDS             complement(26141..26926)
                     /locus_tag="J8S10_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAZ9628886.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWVNNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENNKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            complement(27278..28219)
                     /gene="ribF"
                     /locus_tag="J8S10_000271"
     CDS             complement(27278..28219)
                     /gene="ribF"
                     /locus_tag="J8S10_000271"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HAZ9628887.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGETWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            complement(28223..29146)
                     /gene="truB"
                     /locus_tag="J8S10_000272"
     CDS             complement(28223..29146)
                     /gene="truB"
                     /locus_tag="J8S10_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HAZ9628888.1"
                     /translation="MDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEKKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVERFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            complement(29514..31876)
                     /locus_tag="J8S10_000273"
                     /pseudo
     CDS             complement(29514..31876)
                     /locus_tag="J8S10_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
     gene            32324..32497
                     /locus_tag="J8S10_000274"
     CDS             32324..32497
                     /locus_tag="J8S10_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAZ9628889.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYY"
     gene            complement(32654..33001)
                     /gene="rbfA"
                     /locus_tag="J8S10_000275"
     CDS             complement(32654..33001)
                     /gene="rbfA"
                     /locus_tag="J8S10_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HAZ9628890.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKTAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(33028..35334)
                     /gene="infB"
                     /locus_tag="J8S10_000276"
     CDS             complement(33028..35334)
                     /gene="infB"
                     /locus_tag="J8S10_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HAZ9628891.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSNDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            complement(35347..35658)
                     /locus_tag="J8S10_000277"
     CDS             complement(35347..35658)
                     /locus_tag="J8S10_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HAZ9628892.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            complement(35655..35948)
                     /locus_tag="J8S10_000278"
     CDS             complement(35655..35948)
                     /locus_tag="J8S10_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HAZ9628893.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            complement(35970..37145)
                     /gene="nusA"
                     /locus_tag="J8S10_000279"
     CDS             complement(35970..37145)
                     /gene="nusA"
                     /locus_tag="J8S10_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HAZ9628894.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            complement(37168..37641)
                     /gene="rimP"
                     /locus_tag="J8S10_000280"
     CDS             complement(37168..37641)
                     /gene="rimP"
                     /locus_tag="J8S10_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HAZ9628895.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            complement(37786..42144)
                     /locus_tag="J8S10_000281"
     CDS             complement(37786..42144)
                     /locus_tag="J8S10_000281"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HAZ9628896.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIH
                     IQLGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSF
                     IVKKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYA
                     PEGEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGK
                     KAGVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAV
                     KMYKGNVIESFDEFIDPGHPLSRTTVDLTGITDGMVRGSKSEEEVLRMFLEFSKDTIL
                     VAHNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSL
                     EQHHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILA
                     KNQAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKG
                     VEEARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVAT
                     GNVHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEI
                     VVENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRL
                     KKELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAP
                     HYYCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPD
                     IDLNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSA
                     EVDRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHS
                     IHDNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIY
                     SKTGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDAT
                     LAEVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVP
                     DWYIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMC
                     KGKDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFV
                     IEGDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGV
                     LKDLPDENQLSLFDML"
     gene            complement(42356..44065)
                     /locus_tag="J8S10_000282"
     CDS             complement(42356..44065)
                     /locus_tag="J8S10_000282"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HAZ9628897.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTNLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELVNTLPILLN
                     QGE"
     gene            complement(44133..45401)
                     /gene="rseP"
                     /locus_tag="J8S10_000283"
     CDS             complement(44133..45401)
                     /gene="rseP"
                     /locus_tag="J8S10_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HAZ9628898.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAILLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPDKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            complement(45562..46362)
                     /locus_tag="J8S10_000284"
     CDS             complement(45562..46362)
                     /locus_tag="J8S10_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HAZ9628899.1"
                     /translation="MKQRVVTAAVALVLFIPIIWIGGIAVELTAAILAVIGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            complement(46359..47171)
                     /locus_tag="J8S10_000285"
     CDS             complement(46359..47171)
                     /locus_tag="J8S10_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HAZ9628900.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            complement(47366..47923)
                     /gene="frr"
                     /locus_tag="J8S10_000286"
     CDS             complement(47366..47923)
                     /gene="frr"
                     /locus_tag="J8S10_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HAZ9628901.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(47926..48648)
                     /locus_tag="J8S10_000287"
     CDS             complement(47926..48648)
                     /locus_tag="J8S10_000287"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010761216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HAZ9628902.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(48784..49665)
                     /locus_tag="J8S10_000288"
     CDS             complement(48784..49665)
                     /locus_tag="J8S10_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HAZ9628903.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(49764..50546)
                     /gene="rpsB"
                     /locus_tag="J8S10_000289"
     CDS             complement(49764..50546)
                     /gene="rpsB"
                     /locus_tag="J8S10_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HAZ9628904.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            50905..51384
                     /locus_tag="J8S10_000290"
     CDS             50905..51384
                     /locus_tag="J8S10_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HAZ9628905.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            51601..52692
                     /gene="phnW"
                     /locus_tag="J8S10_000291"
     CDS             51601..52692
                     /gene="phnW"
                     /locus_tag="J8S10_000291"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HAZ9628906.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            52685..52813
                     /locus_tag="J8S10_000292"
     CDS             52685..52813
                     /locus_tag="J8S10_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HAZ9628907.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIR"
     gene            52817..53362
                     /locus_tag="J8S10_000293"
     CDS             52817..53362
                     /locus_tag="J8S10_000293"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HAZ9628908.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEG
                     SSLMGISYDEYQKLEMGKKIV"
     gene            complement(53816..55507)
                     /locus_tag="J8S10_000294"
     CDS             complement(53816..55507)
                     /locus_tag="J8S10_000294"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HAZ9628909.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(55927..56874)
                     /gene="arcC"
                     /locus_tag="J8S10_000295"
     CDS             complement(55927..56874)
                     /gene="arcC"
                     /locus_tag="J8S10_000295"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HAZ9628910.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(56989..58008)
                     /gene="argF"
                     /locus_tag="J8S10_000296"
     CDS             complement(56989..58008)
                     /gene="argF"
                     /locus_tag="J8S10_000296"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HAZ9628911.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(58099..59328)
                     /gene="arcA"
                     /locus_tag="J8S10_000297"
     CDS             complement(58099..59328)
                     /gene="arcA"
                     /locus_tag="J8S10_000297"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HAZ9628912.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
     gene            59789..60490
                     /locus_tag="J8S10_000298"
     CDS             59789..60490
                     /locus_tag="J8S10_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAZ9628913.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(61099..62115)
                     /gene="tsaD"
                     /locus_tag="J8S10_000299"
     CDS             complement(61099..62115)
                     /gene="tsaD"
                     /locus_tag="J8S10_000299"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HAZ9628914.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALAAKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(62112..62576)
                     /gene="rimI"
                     /locus_tag="J8S10_000300"
     CDS             complement(62112..62576)
                     /gene="rimI"
                     /locus_tag="J8S10_000300"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HAZ9628915.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(62583..63125)
                     /gene="rimI"
                     /locus_tag="J8S10_000301"
     CDS             complement(62583..63125)
                     /gene="rimI"
                     /locus_tag="J8S10_000301"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HAZ9628916.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(63109..63933)
                     /gene="tsaB"
                     /locus_tag="J8S10_000302"
     CDS             complement(63109..63933)
                     /gene="tsaB"
                     /locus_tag="J8S10_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HAZ9628917.1"
                     /translation="MYYCTSFAFGIFILRIKKYATMEGENVIAERIKYMITLGIDTAN
                     QTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAIDQLFADLQISPKDIDRIAVSDGPGS
                     YTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAANCIGVDNIIVPMFDARRKNVYAGAY
                     RWKENRLETVLEDVHISASDLFTQLQKLNEAIYFVGSDCHKFFSEIKEILPSAMINTV
                     PAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKRVEAEEKWLETHTPGDESYVEKI"
     gene            complement(64022..65002)
                     /locus_tag="J8S10_000303"
     CDS             complement(64022..65002)
                     /locus_tag="J8S10_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAZ9628918.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(65026..66510)
                     /gene="galT"
                     /locus_tag="J8S10_000304"
     CDS             complement(65026..66510)
                     /gene="galT"
                     /locus_tag="J8S10_000304"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HAZ9628919.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(66522..67511)
                     /gene="galE"
                     /locus_tag="J8S10_000305"
     CDS             complement(66522..67511)
                     /gene="galE"
                     /locus_tag="J8S10_000305"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HAZ9628920.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            67759..67926
                     /locus_tag="J8S10_000306"
     CDS             67759..67926
                     /locus_tag="J8S10_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HAZ9628921.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(67988..69799)
                     /locus_tag="J8S10_000307"
     CDS             complement(67988..69799)
                     /locus_tag="J8S10_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HAZ9628922.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(69796..70161)
                     /locus_tag="J8S10_000308"
     CDS             complement(69796..70161)
                     /locus_tag="J8S10_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HAZ9628923.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(70324..70719)
                     /locus_tag="J8S10_000309"
     CDS             complement(70324..70719)
                     /locus_tag="J8S10_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAZ9628924.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(70737..71699)
                     /locus_tag="J8S10_000310"
     CDS             complement(70737..71699)
                     /locus_tag="J8S10_000310"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HAZ9628925.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(71699..71911)
                     /locus_tag="J8S10_000311"
     CDS             complement(71699..71911)
                     /locus_tag="J8S10_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HAZ9628926.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(71932..72630)
                     /locus_tag="J8S10_000312"
     CDS             complement(71932..72630)
                     /locus_tag="J8S10_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HAZ9628927.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(72650..73192)
                     /locus_tag="J8S10_000313"
     CDS             complement(72650..73192)
                     /locus_tag="J8S10_000313"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HAZ9628928.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(73324..74328)
                     /locus_tag="J8S10_000314"
     CDS             complement(73324..74328)
                     /locus_tag="J8S10_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HAZ9628929.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILPSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(74325..75314)
                     /locus_tag="J8S10_000315"
     CDS             complement(74325..75314)
                     /locus_tag="J8S10_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HAZ9628930.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVEKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(75311..76117)
                     /locus_tag="J8S10_000316"
     CDS             complement(75311..76117)
                     /locus_tag="J8S10_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9628931.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            76283..77239
                     /locus_tag="J8S10_000317"
     CDS             76283..77239
                     /locus_tag="J8S10_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAZ9628932.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(77316..77834)
                     /locus_tag="J8S10_000318"
     CDS             complement(77316..77834)
                     /locus_tag="J8S10_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAZ9628933.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(77922..78071)
                     /gene="rpmG"
                     /locus_tag="J8S10_000319"
     CDS             complement(77922..78071)
                     /gene="rpmG"
                     /locus_tag="J8S10_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HAZ9628934.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            78299..78745
                     /locus_tag="J8S10_000320"
     CDS             78299..78745
                     /locus_tag="J8S10_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HAZ9628935.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(78940..80835)
                     /gene="asnB"
                     /locus_tag="J8S10_000321"
     CDS             complement(78940..80835)
                     /gene="asnB"
                     /locus_tag="J8S10_000321"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HAZ9628936.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
BASE COUNT        22906 a        17296 c        14106 g        26792 t
ORIGIN      
        1 aaatttgtct tcgccaacac aatttgacga agagcctttt ttctttggat taaactgctt
       61 cttcacgcag tttttccgca aattcattta ttttgcgaat tcggtgatta attcccgatt
      121 ttgatattgc acctgaggga atcatttccc ctaattcttt caagctgacc tctggatgtt
      181 gaagccgaag ttctgcgatt tcctgaagtt tttcaggaag ggcatgtaga ccgacctttg
      241 cttcgatcaa ttcgatgttt tcgatttgtt tagaagccgc atcaatcgtc ttgttcagat
      301 ttgctgtctc acaattgact agacgattga ccgaatttct catatcccgt acgattcgaa
      361 catcttcaaa tcggagcatt gagttggttg caccaatcaa tgttaagaaa tcagcaattt
      421 tttctgctcc ttttaaatac gaaatatagc cattgcgccg ttcaagcgtt cgagcatgta
      481 gaccgtaata atttaacata tcgcaaatgt cttggttatg ctgttcataa atagaaaata
      541 tttccaaatg ataacgactc gtttccggat tattgactga acctgaggcc ataaaagcac
      601 cacgtaagta agaacgcatt ttttgcgaat ttcccataat ctcgtccgaa acgtgtccat
      661 tgaacatcat accatccatg atatcaagat ccatcaacac atcttttgtg ccttgcttca
      721 accggacgat atagacattg ttctttttta atttcatttt tttacgaacg agtagctcac
      781 ttcgtacctg ataatgatct ttcaaaagag aatagatacg tctggcaatt gcagcatttt
      841 ctgtttggac gttcaaaata aactgctggt tcacaatacc taaagagccg ttcattcgca
      901 gcaaagcagc taattccgct ttcgcatgtt ctcgatgaac ttccaaacca gttagttctt
      961 tcttcacatc tgcagcaaat gacatcctat tctcctcctt tctccaacaa taaattgctt
     1021 aatattttga accgaaaact aaacggaaca attcttctac tactttgtct ccatcgtgga
     1081 agacaccacc atctttcaat tctaaaaagt cggtggaaat cactcgacat ccttcatttc
     1141 tcaatccgtt gaagtcgtgt gcgacttgta ctagatactc atcatagatc tctgggtcca
     1201 tataatcttc aggcactttt tccgtattga ccaatactgt atcgataaaa ggctgattca
     1261 aatgcttgtg taaaacacgt atatgatcgg catctgtgaa atgttccgtt tccccttttt
     1321 gggtcatgat attacagata tagacggttt cagcagttgt cttgagcatt gcttcgccga
     1381 tttctggtat cactaaattt ggaaggatac tggtgaataa acttccgggt cccaaaacga
     1441 ccatgtcggc gtccataatt gctgaaacga cttttcgagc cgctttggct tcacttttat
     1501 catttgtgtt gcagacatac acacggtcaa tggttttacg gttgatcgcg attttagatt
     1561 ctcctactgc agtcgttccg tctttaaaaa cagcatgcaa ggtcaaagga gtttctgaag
     1621 aaggataaac atgtccatct acatgcatca tttttgctaa taattgaatc gcctcataag
     1681 tgcttccccg catctcggaa actgcggcaa tgatcagatt accgatcgta tgattggcta
     1741 aaaactgatc ttcctttttg aaacggtatt ggaaaatatc ttcatagaat tgtggcatat
     1801 ccgataacgc cactaagaca tttctcaagt caccaggagg agccatagcg atcgattctc
     1861 tgattgcacc gctgcttcca ccatcatctg caacagtcac tactgctgtg atatctgctc
     1921 cttgatttcg taaacttttc aggataactg gcagaccagt gccaccgccg accactacga
     1981 tctttggttt tcttatccgg taggttttca ttttcacgac cggttcaccg tctctttcct
     2041 tttatccttg tcccgatgtg tcacattgac tttatagttt ttccctaaag catttgccaa
     2101 acgttcagtc aatgccacag aacggtgttg accgcctgta cagccgattg caactgtcaa
     2161 gctgcttttt ccttctttaa tgtatccagg caatacagtt tccagaagat ccaaaaattt
     2221 atggtagaat gattgcgttt catcaaagga catcacataa tcatagactg gctgatcttt
     2281 tccggtcaat ggtcttagtt ccgggatata atgagggttg ggcaaaaaac gcacatccat
     2341 cacaatatcc gaatcgatcg gcaacccgta tttaaaacca aatgatacaa attcgatccg
     2401 aaatccttgg tctccctttg atttgaatga ctcattgatt ttttcacgta attgtcgtgg
     2461 tgtcaatgtt gtcgtatcaa tgatcacgga agcttgggct ttcaagtcgt ctagtatcgc
     2521 ccgttcttta cgtatccctt cagtgatcaa accgtccatc gccattggat gtgctcgtct
     2581 tgtttctttg tagcgagcca ctagttcttc gtctgaagca tctaaaaata agatagaagt
     2641 gtcgatgaag ttcgtatttt cgatttcgat cagcatgttt tggatttctt caaagaagga
     2701 acgagaacgc aaatccactc ctaaagccat ttttgtgact ttacctgatt ctttgatcaa
     2761 ttcccagaat tttggaatca atcgaggcgg catattatcg atacaaaaat agcccatatc
     2821 ttcaaaactt tggatagcta ctgttttccc tgcaccactc atacctgtta tgatgactaa
     2881 ttgcaaatta tctgtcatat ttacgaaccc ctctcacatt gtgcataata aaattatatc
     2941 atcccgggcg tatcattacc agttttcttt ttcttttaca aaaagatttg gaccaaatat
     3001 cttttaggat atttgcccca aatccaattt ttttactttt ccgatgctgt atccaatgcc
     3061 tcgcttcttt cagctaatgc acgttcgatc gttcgatccg ctaaaataga ttgagcatcg
     3121 atcactgggt aatgattatc ttcagcaaat tcatgcatca aagataattc tgtgcaacct
     3181 aggatgactt tttcacagtt taggcgctct accgcttcct ctaagatttc gtaatagagc
     3241 tcttgattca aataatccga ttccttgatc tcatgataga tcaggtaatt gattttttct
     3301 tgaagcgcag tatcaggaat cactgtttcg aaaccaagat ttttgacttc gcgttcatag
     3361 attccagctt tcatacttcc ttctgttcct agaatcgcta ctctccctgt cgtatgctga
     3421 cggacaagtt catttgctgc ttctcttggc atatgcaaga taggaatatc cgttgccgct
     3481 tgtaactctt caaaaaagta gtgtgcggtg ttacaagtca acacaatgaa gtttggtcgc
     3541 aataaatttt gtttctcaat atcatccagc agaaacggca ttggattttc ttctgatcga
     3601 tctaaaatat aagctgtacg atcaggaact gttgcatgat tgaataagac ataattcaaa
     3661 tattcttgat cttttgtagc tttcgttcgg tggttgatca agcgaacaaa actttctgtc
     3721 gccatcgtgc ccattccgcc taaaatactg aaaaaattct ccatgaacta gccttctttc
     3781 acatgaaaat actttttgaa tcttggaata tagttatgga acatatattt catcaacaac
     3841 cagcgcttga ttgatcggtc tttttcataa aatacagtag taccgtaacg attttctttg
     3901 atcatttgct cagctagttt tttgtcttca ttttcccgag catattctaa aaagattttt
     3961 ttgggcacac ccatccataa tcttgcttta tctgattgat tcgttccata ggtcgtttca
     4021 acaaagggtt tgttgaacac tcgatcttct gtgacaaaac gagccagatt caagccgttc
     4081 aatgtcacaa agaaactgct acgaccttgt ctcaaattga tttcaaataa tttatattct
     4141 ccatctctag gatcatactt catatcgaaa ttggcaaagc ctgtatattc gattttttcc
     4201 aaaaatgcct taatggtttg atagattttt tcgttataat ctggcatgat cacaacgtaa
     4261 ttaccaatcg atgctggtgt aggatcttct aatagtggat gaccaaggca catcatccga
     4321 acttgatgat cttcatctac atacgcattt agcacacgca tattactatc atcacccggg
     4381 ataaaatctt gtacaatcat ttcactttta taaccggctt cgtatatccg gcctaaaatt
     4441 aaatcgaact cttctctagt ctctaaaata aaagcttttt ttcttccttc aaattggaca
     4501 gaaagatact ccacactgtt tgcaggtttc aaagcaactg ggaattcaaa aggcaattcc
     4561 tgttccaaat gtccatttac taacatttct tctctgacga tcaatgtttt aggatacgga
     4621 agatcatatt cttcacaaac ttcataaaag cttactttat tgatcagcct ttcaaataaa
     4681 gaataatcaa tatatggaca gataaaatat tctgacagct cttgtttatg ttgggagatc
     4741 aattctgcat atccatcacc acaagcaatc aaaagatatt ttttactctt atcagaatat
     4801 ctttcttttg ccaaacgaag catcgtctcg ataaatacag ggtctttatc aaatcctgga
     4861 ataacttcta cattgacaat tttactgtag cgggtagggg ctaactgatc cgaagcatat
     4921 gcttggcaga ttttgccgta tgcttcatta aaagaacgtg ccataccata aacgttcatg
     4981 tcgcttccta ataatatagg gataaattct tcattttcaa tactgttcat cattatctct
     5041 cacttactca taatctcttg tttttctttt ccaactacac aaggaatatc ataccataaa
     5101 gaaaaaagca atcaaaggaa agtcctccga ttgctcaatt cttttttgaa cggattgaac
     5161 ttataggaag tttttatcta taccaatcag tgtagaaaga actaccatgt aatgattcta
     5221 gaacactgat attaataaaa caagcaaaaa ttcatttttt tatgtttttt taactatctc
     5281 agctatctat cctctttata ccattatttt tttcaaatag tgacctgtat aactttcttt
     5341 tacgttaatg atttcttctg gtgttccagt cgcaaggatc gttcctccac cttctccacc
     5401 ttctggtcct aaatcaatga tataatctgc tgttttgatt acatctagat tgtgttcaat
     5461 cactaaaact gtgttaccag catctactaa tctttgtaat acatgcaaca agcgggcgat
     5521 gtcatcgcta tgaagtcctg tcgttggttc atctagtata tagaaattct ttccattaga
     5581 gattttgtgc aattcactgg caagtttcat ccgttgtgcc tcaccaccgg acaatgtcgt
     5641 tgctggttgc cccatcgtca cataacctaa gccaacatca acaatcgttt gcagtttgcg
     5701 atgaatcttt ggaatgtgct tgaagaattc tacagcatcc tctactgtca tttccaaaat
     5761 atcagcaatg ctttttcctt tgtaatgcac ttctaatgtt tcagaattat atcgtttacc
     5821 atgacatact tcacaaggaa catagacatc aggcaaaaag tgcatttcga tcttaataat
     5881 tccatccccg cgacaagctt cacaacgacc gccttttacg ttgaaactaa aacgcccttt
     5941 cttataaccc cgcatttttg cctcgttcgt ttgagcaaat aacccacgga tatcatcaaa
     6001 tacacttgta taagtcgctg gattacttct cggcgtccgg ccgattgggc tttgatcgat
     6061 atcgatgatc ttttcgatac tttcgtagcc ggaaattgtc ttgaatttac ctggcttagc
     6121 agaattctta tttaattttt gcgctaacga tttctttaag atactattga ccaatgtact
     6181 ctttccagaa ccagacacac ctgtgactgc tacaaattct cctaatggaa attcaacact
     6241 aatatttttc agattgtttt ctgaagcacc agtgatcttg attgctttcc cattaccttt
     6301 acggcgttct tttggtacag ggattgattt tttccctgaa agatatttcc ctgtcaaaga
     6361 attttcatca ttagctactt cttcaggagt gcctgcagcc acgatttgtc cgccttgttc
     6421 tccggcccca ggtccgacgt caatcaaata atctgctgcc cacatcgtat cttcatcatg
     6481 ttcgactaca acgagggtgt tgccaagatc acgcattttc tttaatgagc caatcagtcg
     6541 atcgttgtcg cgttgatgca atccgatcga tggttcatct aaaatataca aaactccaga
     6601 aagattcgat ccaatttgtg tagccaatct gattcgctgc gcttctcccc cagataatgt
     6661 tccggaagcg cgactcaaag ttagatagtc tagtcccaca ttttccaaga atgaaagtct
     6721 gtcatttact tcttttaaaa tcggtttggc aattactttc tcttgttcag ataacgttaa
     6781 gtttgagaag aaatctactg ctttttgaat agacaactca tttgtttgcc cgatattcgt
     6841 tccattgatt tgaacagata gagcttgggg attcaatcga taacctttac atgtctgaca
     6901 agttaattct gtcatataaa gacgcatttg ctcacgcgtg aaatcactgt tcgtatcatg
     6961 ataacgacgc tcgatattct tcaatacccc ttcgaaagtc gtttctacat cgcgaacgcc
     7021 accaaaatca ttttcataat ggaaatggaa aagatcatct gtcccattca agatgatctc
     7081 ctgatgctct tccggtaatt cttcgaatgg tgtatctaaa tcgataccga aactttcaca
     7141 agcctgcgct aacatttgag gataatactg agagctgatt ggattccatg gaacgatagc
     7201 accttgacta agtgtcttcg ttctatctgg aatcactaaa tcttgatcga cttctaattt
     7261 gacacctaaa ccatcacagt ctggacaagc tccaaaaggc gcattgaatg agaacagtct
     7321 tggttctagt tcgccaacag taaatccgca ataaggacag gcatagtgtt cgctaaacaa
     7381 catttcttct tcaccgatca cgtcaaccag agcatagccg tctgctaatc gcagggccgc
     7441 ctctaaagaa tcaaataggc gagaacgaat cccttctttc acaatgatcc ggtcgatgac
     7501 gatcgcgata tcatgttttt tgtttttctc cagctcaggc acttcactta aatcatagat
     7561 ctcaccatcg actcgaacgc ggacgtatcc ctctttttgg attcgttcga atattttttt
     7621 atgttgtcct tttttcttta ccacgatcgg tgccaacact tggatctttg tgcgctcagg
     7681 caaagccatt acttgatctg ccatttgatc tactgattga ctggtaatct cgatatgatc
     7741 gttgggacaa atcggatgtc ctacacgtgc aaacaacaag cgtaaatagt cattgatttc
     7801 cgtcacagta cctactgtcg accgaggatt tttacttgtt gttttctgat caatagaaat
     7861 cgccggactc aatccgtcga tgctatctac gtccggctta tccatttgtc ctaaaaactg
     7921 acgagcataa gcagaaaggc tctctacgta tctccgctgc ccttcagcgt acagcgtatc
     7981 aaatgctagg gaactttttc cagaaccgga caaacctgta acgaccacga atttatctcg
     8041 tggaatcgtt acatctatat ttttcaagtt atgggcacgt gcaccatgaa tcgtaatttt
     8101 atcgttagcc atgttgtcct cctactttga agcttttaat tctaaaatca tatctcgcac
     8161 attcgcggct gtttcaaaat ccaaagcttt tgccgcatct ttcatttctt tttctaattt
     8221 catcaataac gtgtcttttt cttccttcgt catttcttcg tacgagactt gtaccgcttc
     8281 ttttgtatca tcttccgatt ctttcgtaat agaaatcaaa tctcggattt ctttaatgat
     8341 cgtttttgga acgatcccat gttcttcatt gtacttctgc tgaatcgtac gacgtcttga
     8401 cgtttcatcc atcgctagac gcatagaatc tgttactttg tctgcgtaca tgattacttt
     8461 accttcttca ttccgagcag ctcgtccaat cgtttggact aaggaacgtt cactacgtaa
     8521 aaagccttct ttatccgcat ccaagatagc aacaagggaa acttcaggta cgtctaatcc
     8581 ttcacgaagc aaattgattc caactaacac atcaaattca cctaatcgaa gatctcgaat
     8641 gatttctgtt cgttccagcg ttttgatatc actatgcaaa tatttgactt tgatccctaa
     8701 ttctttgaaa taatctgtga ggtcttctgc catttttttc gtcaatgtcg ttacaaacac
     8761 ccgctggtct ttttcgactc gttcatttat ttcgcctact agatcatcga tttgtcccat
     8821 gattggacga acttcgatca ctgggtcaag cagccctgtc ggacggatga tttgttggat
     8881 aacggtatct gtttgttcat gttcatatgg tcctggcgtc gcagagacat aaatgatctg
     8941 attgacatgt ttttcaaact cttctaaccg aagtggccga ttgtctaaag cagatggcaa
     9001 acggaaaccg taatctacta gcatctgttt tctcgctcgg tcaccattat acattcctct
     9061 gatttgaggc atggttacgt gcgattcgtc cgccacgatc aaaaaatctt caggaaagaa
     9121 atccaatagc gtataaggcg gttcaccttc tttacgtccg tccatatgcc gagaataatt
     9181 ttcaattccc gacgtgtagc ccatttctaa catcatttca atatcgtaat tggttcgctg
     9241 ttctaaacgt tgagcttcca gaagtttgtt ttcatttcgc aagacagtta aacgctgttc
     9301 taattccgct ttgatattcg ctacggcatg ctccatatgt tcatcattcg tcacaaagtg
     9361 agtcgccggg aagattgcta cgtgttccgt ttctcctaaa acttcacctg tcagtgcatt
     9421 gacttctcgg atacgttcga cctcatctcc aaaaaactcc acacgtaagg cacgttcatc
     9481 tcttgaagcc ggaaaaatct ccacgacatc accgcgcact cgaaaacgac cgcgctgaaa
     9541 atctatatca tttctttcga attggatact gactaagtca cgaatcaact gattgcgatc
     9601 tagttctgct ccctgtcgaa tcgaaactac ttgtttttgg tactcaaaag gcgagcctaa
     9661 tccaaaaata catgaaacgg atgcaatgac gatcacatca tttctttcta ataatgaact
     9721 agtagccgaa tgtcgtaatt tgtcgatctc atcatttaca cttgaatctt tttcgatata
     9781 cgtatcgctt gaaggcacat aagcttcagg ctgataataa tcataataag aaacaaaata
     9841 ttcaacagca ttgttaggga aaaattcctt gaattccccg tacagctgac cagccaatgt
     9901 tttgttatgg gcaataatca gtgttggttt attcactttc tcaataagat tggaaatcgt
     9961 atatgttttc cctgttccag tcgcacctaa taagatttgt gcttttttcc cgccgactac
    10021 gccatccact aattggttaa tcgcttcagg ctgatcacca gccggttggt atttcgagac
    10081 aagctcaaag tgtcgggagg tatctctctc aatcattctt cgtcctcctt ttcattcatt
    10141 ccttttcatt ttacgaccaa taaaaagaaa aggaaagcaa aggcattcct tactaaaaaa
    10201 ttataccaca ccgaacatac tttcgccact tttttatctt attatacatg ttatgtttta
    10261 taacataaaa tgttagaaac tcgcattttt ttcatttttt cgagcttaca gtcttgtctg
    10321 attcagcact tttcgcctat aataataaaa tattggaaat ttaggaggtt gattatgaaa
    10381 agaaagcatt tatttcactc atttgttttc ttaatgacag gacttgtgac acttgcgttt
    10441 ggtcatgttg cacaagctga caacactaca acggcagagt caagcacaag cgagacaatg
    10501 caaaaaatag agcccaaaaa agacgtatac gtaattgcca gtgactctgc ttttgctcca
    10561 tttgaatttc aaaacgcaaa gggcgagtac gaaggcatcg atgtaaaatt gatggaaaac
    10621 atcgccaaac tgcaaggatt taacatccga atggactacc gtggtttctc tgctgctttg
    10681 caagctttgg aatcaggaca agcagacgga atgattgccg gaatgactgt aacagatgaa
    10741 cgaaagaaaa gctatgattt ttctgattct tactttgata gcgggatcca attagctgtc
    10801 aaaaaaggag atacttcgat caagtcttat gaagatttga aaggaaaaac agtcggagca
    10861 aaagttggta ccgaaagtgc tgaattttta agcgaccatg aatctgaata tggctattct
    10921 atcaaatatt ttgatgctgc tgatcaattg tacgacgggt taaaagttgg cgcaatcgat
    10981 gcaatgatgg atgattatcc ggtaatcggt tatgcgatca aacaaggaca agaattggaa
    11041 acaccgatca aaaaagaatc tggcggaaaa tatgcatttg ccgttaaaaa aggacaaaat
    11101 cctgagcttc ttaatatgtt caatgaagga ttgaaagaat taaaaagaac aggcgaatac
    11161 gataagatta ttaaagaata tgtagcggat ggttcagaaa cttccagtga gtcttccact
    11221 gctgatgaat caacatttct tggacttatc caaaacaact atcaagcatt gttgaaagga
    11281 ctttggagaa caattctcct aactttgatc tcctttgctt tggctatagt aatcggtgtg
    11341 atttttggat tattcagtgt agcaccaata cgcgctcttc gcacaattgc tagtatttat
    11401 gtcgatatca tccgaggaat tccaatgatg gttcttgcgt tctttatttt ctttgggttg
    11461 cctggtatcg ttggatttac gattcctgac ttccttgctg gtgttatcac cttgactctt
    11521 aacgcaagtg cttatatcgc agagattgtt cgaggcggga tcaacgccgt tcctgtcgga
    11581 caaatggaag cttccagaag tttaggtctt tcttataatc ggacaatgca aaaaatcatt
    11641 ttgccgcaag cgatacgcat catgatccca tcattcgtca atcagttcgt tatctcatta
    11701 aaagacacaa cgatcatttc cgcaatcggt gtagtcgaat tgctgcaaac tggtaagatc
    11761 attgttgcac gtacaacaca aagtacgtat gtttacttga tcattgcgat catgtacttg
    11821 attttgatca cagcattgac aaaattagca aaagttttag aaaagaaggt gaagtaagat
    11881 ggcagaaaaa atcttagttg agcatttagt caaaaaatac ggcgataaca cagtattaaa
    11941 cgacatcaat gtatccatca acgaaggaga tgtcgtctgt atcattggcc cttcaggttc
    12001 aggaaaaagt acattcttgc gttgcttgaa tcgtttagaa gaaccttctg acggtgaaat
    12061 tattattgac ggcgcccact tgatggataa aagcacagat atcaacttgg tgagacaaca
    12121 tatcggaatg gtattccaac actttaacct attccctcat ctttctattt tggaaaacat
    12181 cattttagca ccgatggacc tgaagaaaga atctagagaa gaagcagaga aaaaagcaat
    12241 caaattactg cagacagttg gtctagaaga taaaaaagat atgtatcctg aaatgctttc
    12301 tggtggacaa aaacagcgtg tggctattgc tcgtgctcta gcgatgaacc ctgacatcat
    12361 gctttttgat gagcctactt ctgcactcga tcctgaaatg gtcggtgatg tcttgaacgt
    12421 catgaaaaag ttagcagaac aaggtatgac gatggttatc gttacgcacg aaatggggtt
    12481 cgctaaagaa gtggccaatc gcgtcatgtt cattgacgac ggaaactttt tagaagatgg
    12541 aacgcctcaa caaatctttg aaaatccgca aaatgaacgg acaaaagatt tcttgaataa
    12601 agtattaaat atttaataaa aaccaaaaat gcacggtcgc catgaaggga ccgtgtattt
    12661 ttatcttctt attttctcac ctaatcgtat cagccgcatc gcttgttttc ctgcacaaac
    12721 aagcaatcgc tctacctgtt ccatcgcata agaaagtacc atcggttcat tgatgatatc
    12781 aagtacatag tcgataccac cctcacttaa ttgagcttga tttttcttct ccatattatg
    12841 tagttgtggg acaactttct gacaatcagc aattgtgtca agaacggatc aatcctttat
    12901 tggagttgct cgaaagggtc ttctcttatt acggacaggc tttgctcact gtacatagac
    12961 aacaaatcat tatcctagtc aatcggattt ccagagcctc attgctatca ttgcttgata
    13021 aaatccagac aaagtttaat aaaatgtatc agttacagct aaactttgga attgggtcgc
    13081 tttgttatac agagcaagag acaccgcaat ctttccttca tgccaaacaa gtttgcgaat
    13141 ggatagcttt ccatcaatct gtgaacgaga tccgcttttt tgaagattta gacctcggga
    13201 tcgttttacc agcaatcccg tcagatcaac gaacattata tgtaaaacgt attttgaaaa
    13261 gcctgacaga agaagaagta catttgttca agaagacttt ggcatgcttc agtaaaaata
    13321 acggaagcat caaaaattgc tcagaagaat tatttattca taaaaacacc ttgcaatatc
    13381 gattgaacaa gttccattct ctcactggtt atacccctag aaactatgac gattatcata
    13441 ttctaaagct ggcttttttg ttggtacaaa catgacaact acaaaaaaac caggcgaaca
    13501 tatgattgtt cgtctggttt ttaattatta atgacttagc gtttttacta gaaaaactac
    13561 ttccgctttt tcccgccaaa agcatcttta aacttatcga agaaaccgtc ttcttgctgt
    13621 tcttcaactt tgatgccgcc agcttcagcg aatgcacgta atgcttctct ttgttgttca
    13681 tttagatttt tcggtgtgat cagttttact ttgacatgtt ggtcgcctgt tgcaccacca
    13741 cgtaacttcg gagcgccttt tccacgtaaa cggaagttcg tacctgtctg tgttccagca
    13801 gggatcttca atttcacatc tccatggaca gttggtactt ggacttcatc ccccaaagct
    13861 gcttgtacaa aacttaaagg caattcatag taaatttcag aaccttcacg atcaaagata
    13921 tcactttctt ctacacggaa gaccacatac aaatcaccaa atggtccgcc gttttctcca
    13981 gcttctcctt gaccagctaa acgcatttgt tgtccttctt ctacaccagc tggtacattc
    14041 actttaactg aatgtgcttt cttctcatgt cctgagccat gacaggttgg acaaggttct
    14101 ttgatttctt tccctgtccc atgacaaaca tcacaagttt gacggctcat cactcgtcca
    14161 agtggtgttt ggcgttctac attaatcgta cctgcaccat gacatttatg acaagtagtt
    14221 ggttgtgtgc ctggttttgc accgttccca ccacaagtat gacagatttc ttcccgatta
    14281 tacttgattt ctttttctac accaaaaatc gcttcttcaa aagacaagtc gaccgtatat
    14341 tgcaaatcag caccttgacg aggcgcattt ggatcgactg accgaccgcc tcctccaaag
    14401 aaagagtcga agatatcttc aaaaccaccg aagccgccac cagagaagcc gccgaatcca
    14461 ccaaatccgc caccagctcc accagcaccg taatttggat ctgtgcctgc atgcccgtat
    14521 tggtcatatg cagcgcgttt ttgcgggtca cttaaaatct catatgcttc tgatacttct
    14581 ttgaattttt cttccgcatc aggttcttta ttgatgtcag gatggtattt tttcgaaagc
    14641 ttacgataag ctttctttat ttcatcttct gatgctcctt ttgagagccc taagacttca
    14701 taataatcac gttttgttgc cataggcttt cctcctattg gttctcatca ttttcacgtc
    14761 gcttgttatc atatcatatt ttgtttgaaa caaaaaccga tacttcaaac tatttttcaa
    14821 aagaaaaagc caaagtagca actttggcct tctctcgaaa ttcagtgaac tgattattta
    14881 tcgtcgccat cgacttcttc aaaatcagca tcaacgacat catctgctcc gccttgagct
    14941 gcttctgggt tttcttgagc ttgttgttgt gccgcttgtt cgtatagttt aacagtcaag
    15001 ttttgaacga tttcgttcaa tgcatcgcgt ttagttttca tttcttcgat gttgtttgct
    15061 tcaacagcgg ctttcaattc atcgcgagct gtttctgctt ttttcacttc ttcttcgtcc
    15121 actttgcctt ctaattcttt caatgttttg tccacagaga atagcaatgc atctacatca
    15181 ttacgtaggt caacttcctc tttacgagct ttatctgctt ctgcatttgc ttctgcatct
    15241 tttaccatac gttcgatttc ttcgtctgtt agacctgaag aagatttgat cgtgattttt
    15301 tgttcttttt gtgtacctag atctttcgca gatacattta caatcccgtt tttatcaata
    15361 tcgaatgtta cttcgatttg tggaatacca cgaggagctg ctggaatatc tgtcaattgg
    15421 aatcttccta gagttttgtt gtcagcagcc attgggcgtt caccttgtaa tacatggatg
    15481 tctactgctg gttgattatc tgccgcagtt gagaatactt gtgatttact tgttggaatc
    15541 gttgtattgc ggtcaatcaa tttagtgaac actccaccca ttgtttcgat acctaatgac
    15601 aatggtgtaa cgtcaagtaa aacaacatct ttcacatcac cagtgatcac gccaccttgg
    15661 atagcagcac ccatagcaac tacttcatca gggttaactg atttgtttgg ttcttttcct
    15721 gtttctttac gtactgcttc tacaactgca gggatacgag tagatccacc gactaaaata
    15781 acttcgtcga tttctgattg tgataaacct gcatctttta gcgcttgacg tactggtact
    15841 tttgtacgtt ctactaagtc agctgttaat tcatcaaatt ttgcacgtgt caatgtcatt
    15901 tccaaatgca atggtccaga ttctcctgct gtgataaatg gcaagctgat ttgtgtgctt
    15961 gatacgccag ataaatcttt tttcgctttt tcagcagcgt ctttcaagcg ttgtaaagcc
    16021 attttgtctt gagacaagtc aatgctgttt tcttttttga attctgctac catgtagtcg
    16081 atgattttgt tatcaaagtc gtccccacct agatggttgt cgccagctgt tgacaataca
    16141 tcaaagacac cgtctcctag ttcaaggata gatacgtcaa aagtaccgcc accaaggtcg
    16201 aatactaaga ttttttcgtc gcgatctgtt ttatctaaac cataggcaag agcagctgca
    16261 gttggttcat tgacgatacg ttctacttct agaccagcga tcttaccagc atcttttgtt
    16321 gcttgacgtt gtgcatcatt aaagtaagct ggcacagtga taactgcttt ttcgactttt
    16381 tcacctaaat agtcttctgc gaatcctttg atatattgaa ggatcattgc tgagatttct
    16441 tgtggtgtat atgatttacc ttctacatct actttgtaac ctgcttcacc gatatggcgt
    16501 ttgattgatg aaatcgtatt tgggtttgtc acagcttgac gttttgcaac ttcccctact
    16561 tggatttctc catttttgaa tgatacaaca gaaggtgttg tacggtttcc ttctgggtta
    16621 gcgatgattt ttgcttcgtt tccttccaat actgctactg cagagttagt cgtacctaag
    16681 tcaataccga taattttact cataattaac gtctccttct ttaattgaaa gtgtaagttt
    16741 tatatccgca caattattgt gcaacaatga ccatggttgg tcttaacacg cgatcatgta
    16801 atttgtagcc ttcttgtagt acttctacaa tcgtatcggc tggtgtatct tcagtcgctg
    16861 gaacagtttg tactgcttga tgaagattag gatcaaaggc ttctccttta gcagggattt
    16921 tttcaattcc ttcttcttcc agtgcgttac gcaaactttc caagaccatt tccacgcctt
    16981 ttttcaaacc tgccccttga tcatctgaca cttctgtggc taatgcacgt tccaggttgt
    17041 caattgatgg aagtaatttt ttggctaaat cttgtgaacg gtatttttgt aattgctcac
    17101 gctcattttt tcctcgattt gccatatttg cgatttcagc acgagcccgc aagtatttat
    17161 cttccatttc ttctaactca gcttttaatt tcgctgtttc gaattcttcc gcttcagctt
    17221 ctgaaatacc cgaatcttct gcagcttcga catcgatttc cggttctggc tgagcatctg
    17281 tcatttcttt atctagttct tcttgatttt ctttcacgat acagtcttcc tttcattatt
    17341 cagtcagctg tttgattgct cttactaaga aagagagaac gatcagctgc aaatagcttc
    17401 gttattcaca ttacgagttt gacaagtcaa gcgaacggta gtaatcagca agtttagctg
    17461 ctagttctct tcgataaaca tcgactagac cgaacatccg agaataaggc atactagtag
    17521 gccctaacaa ggctattgta cctcttccat gaccatctat ctcgtaactt gcttgaatca
    17581 tactcatatt ctgcaataaa tcattgccta attcagcacc aatcttgata tgaatattgc
    17641 tatccatcgg agtgatcatt tgtgtaagtc cgtctgagtc tttcataaaa gaaaacatcg
    17701 atttgaactg atcaagatct tgacggggct cataatccaa gagattcatt tgtccactga
    17761 cataaacctt atcttcaaaa acatgaccaa gaacggtgtc aaataactga gacatccctt
    17821 ctgtcgtttg gaaatattta tgaagaatca tcggaatctc cgtacgaagt ttatggtaca
    17881 ccgtcatcag aggatctccg actagacggt cgtttacaat ctgtaccatt ttttctagtt
    17941 cctgacttcc catatattcg ggaagagtga acacttggct ttctacattc cccatatctg
    18001 ttacgacgat agcaataatc tgtcgattat tcaagggtac gatacgaaag ccagtcagtc
    18061 ggcggtcttt tatttcaggt cccaatgaaa aagtcgtata gcttgtcagc tcagataata
    18121 tctcagcaga ttgcttaata atctcattga tttcatgaaa ttctctgcct agagactgac
    18181 gaatcagcag caaatcatct tctgctacgc gagcaggttt taacaaatga tccacgtaat
    18241 aacgatagcc taaagcagat ggaatccgcc cagaagaaga gtgagtcttc aacagcaatc
    18301 cttcatcttc taatgctttc atatcattgc gaatcgttgc tgagctggcc ttgactccct
    18361 cagacatcaa tgttttggaa ccaacgggca cgccactact cgtatagtgt tggatgatca
    18421 gacgtaaaat gtcgttttgt cgctttgtta acatcttcct cacctctcat tagcactcat
    18481 atattctaag tgctaatcca cttataaata tagcaagaag cccttctcct gtcaagagaa
    18541 agactccatt ttttagcact ctaaacacaa gagtgctaat tctaaataat tgatgtaaat
    18601 ccagttatat caacgtttca atagtccttt attgtatttt tgaacttttt ttatttaaat
    18661 tcagataaaa aacaaatatt ctttaaacta tttttcaaac aaaaagcgct caaacacatt
    18721 gttccccaaa aaggtccctc ttggtgtcaa ataaacacgg tcttcttcat taacaagtaa
    18781 cccttcttgc tctaattccc ttagcacatc accgtacacc gattcaattg ttttttgata
    18841 gcgatcatag aaatgttttt tagtaatccc tgtttttttt cttagtccta agaacatttc
    18901 ttcttctatt tgattttttc gtgtcaattt ttcttcttcc aataccgggc gttcatttgc
    18961 tcgtaatggg cgtaaatagt gttggattgg tcctttgttg cggtaacgaa tatctccaag
    19021 ataaccgcta gcaccagctc caaacccaaa atagtgggca ttgttccagt acatgaggtt
    19081 atgttgagat tcatgtccgg agagcccaaa gttacttatt tcatattggt gacgtccatg
    19141 cttttccatt gcttcaatcg tctcttcaaa cattctggtt tccgtttcct gatcaggcag
    19201 ttcgagtctt ccttgtcgta cccagttcat gaacattgtt ttgttttcga ggatcaatga
    19261 gtacaaagaa tagtgaggca gatccaaagc caaagctttt tccaaagtat ccagatatcc
    19321 ttctagtgtt tgtcccggta atgcataaat caaatcgatg cttacattgg taaaattttc
    19381 tgcttctaaa aattgcatag tttgatacac atcttctgcg gtgtgtttac gtccaatttt
    19441 tttcaataag cgattatcaa atgtctgcac tcccatggat aaacgattga cgccatagtt
    19501 tttcattact tgaagttttt cacgggtcaa atcacctgga ttcgcttcta cagtaaactc
    19561 attaccattt tgaaaaggca ggatctctct agcacctgat aacagtcgat caagttgttt
    19621 agcagataaa gaagttggtg tcccgccccc tacgtaaagt gtttctaaat tcgctgtcgg
    19681 atgactttct agcattattt tcatttcatt cagcagcatt tccacatact catctactgg
    19741 ctgcccttct aaaaaaactt tattaaaatc acagtaatag cagatatgct cgcaaaatgg
    19801 gatatgaatg tacgcagaaa ccttgttttc tgcgggattt attgtttcta tcattgaaat
    19861 tctttctcct tacgtcgaaa agtcgtgcct gttttcgacc ttcttaaaat cgcgttcaag
    19921 caccaactca ttgaaataag ccgcatattt agaatcaagg aaacctagct ctaaaaatgc
    19981 ttgcttattg tcatcggagc tacacggtgc ttttacagcc tctcgataaa cggtaatcgc
    20041 aaagctgacc ttcggcatta agtcaaaatc tgcaaaaata tgaaaagcta ttttcacaga
    20101 ttcctcctta agtgctcaga ccacaacgct ttgcttacaa cctctcatat acgcatacta
    20161 aacgtatttg gcgaacaaat ccactaaaaa atccaagaat cgacttcttg gatgattttt
    20221 tctttcatta aactggttac ctagttatat atctctaggg ttgttttcat gtctgagtgc
    20281 ccgatatgat ttatttttcg tttctataat tactttttgc cttccagttt cttttaatat
    20341 tgtactcaag caagtgggaa ttggttcttt tgtcatccat gtatgcaaaa tgttataatg
    20401 ctggtaaaca aaaatgatta cctgtcattt ttatttagtt cgtatttaat taagttgact
    20461 atctgtatac tctgtctaaa acttaagaat tgttgttttc gctgtcgcta cccaatttta
    20521 atgaatgtct gtaggttaaa actgttgtcc ttgttataga tagtaaagga gagcttgaaa
    20581 atgaaaactg cgattacgtt tctattagag gaatatgccg attgggaagg tgcttatatt
    20641 actagcacac taaaccaaaa tgagaaatgg caaaacaaaa ctgcttctat ccaatcagag
    20701 gtcacttcca ttggaggatt aaaaacaaaa atcgattact taatcgaaca aatacctgaa
    20761 aaagttgacc tttttattat gatcggtggc aattcatggg acataaaaaa tcatcattta
    20821 tatcaaataa tcgataaatt gttaaaaaca gacgtaccag tagctgctat ttgtggggca
    20881 gttgattatt tagctcagag cggattattg caaggttaca aacacaccgg aaatgcgcaa
    20941 tttccttggt tagaatcgga aaattatcag aataaagaag attttataga acaacaagct
    21001 gtgaaagatc gtaatttgat tactgcgaat ggaacagctc ctatagaatt cacagacttg
    21061 attcttcaag cagtccattt tgaaacagaa gaaataagag aaaaaacgat tcgtctatac
    21121 aaacttggat tctatgatta ctataaaaag tacggagatc ctttctccta atcattctct
    21181 tcaattaaat actccttatc aatagtgtga caagtaattt tactgatgat tatttgtcac
    21241 actttttctg acatttatca aagaagatac actctattta tattcataga caaggtttta
    21301 cggattcaaa aattcaggat tatgctatac tggtattaaa aaaataatga ggtattttat
    21361 atgaaaaagt taggttttat tttattgttg gtctctttat tccttgtagg atgtacgtct
    21421 cctagtaaag aaaatagtga tccatctgcg accacagaca aaagttcaat cagacaaacc
    21481 agttcagctg aaaaatcaag tactcagaaa tcagcttcta ctgaaacgaa tacatcttca
    21541 acaagcagta aagtctcaga gcccaatact tcttctacat ctagtagtac agttgagaca
    21601 aatatttctt cttcaacaat agacacaacc tcctcacagt cttctcagtc aatagatccg
    21661 ttagcaggat attctgatct acaaattgag tacgcacgtg tttggctagc tattagaggt
    21721 aatactttta gagatacatc gggtgatttc gaattacatg ttattcatta tcctgcagga
    21781 acacctatcg ccccttatga tgcagggagt gcagtctatc cgaaagatgt ggttatgctc
    21841 actgggaaat acagttacca gggagtttta gtgtattcaa gtaaccatga cgggacaatc
    21901 actagttatc cagttccttc acattggcaa atgcctgcag atcaaacatc ttatccagcg
    21961 ttcattagag aaacaactca agaaatcatt gataatgcat ctgtagtagc tattcctaca
    22021 ggaaatccca atgacgtgaa acagttaatc gatgtgacag ttatagataa ttagactttc
    22081 taatatgtta tacaaaaaga agctgacagc attttgtcag cttctttcac tttcttttct
    22141 atttagattt attggtcttt gatagactcc aaggcaggaa aaaatttttt aaataaacgt
    22201 ttgcaaaaca gtcgcttttc tatcttctac cgctacttct gcataggcac cattaatcaa
    22261 tgtcagttgt ggcggtacat gaccacaatc aatatcatac aagatcggta gttttaattc
    22321 ctttgacaga tcttcgtata catccttcat tttataatct aacaaatcct ctgccgcact
    22381 tctaccgaac atgatccccg agctgccatc aaaccagcct gccagtttca tctgaacaag
    22441 tgatcttctt aaatcaactg acgatagctc acagttttct agaaaccaca agatcggctt
    22501 tccatcatta tactttcttt taaaagattg gacatctcca taaggagtac cgattaaatg
    22561 cctgatcgta tcaatacaac cacctaataa tcgtcccttc atccttactg catctccgct
    22621 gactgattgc caatttgttg gttcagtgag atggaaaaca gaagatgatg aatgctcatg
    22681 gggccacact ttttgatact tttcagaaga ttgctgtaga atcgattctc cttctcttgt
    22741 tttcagtaca ctttcccaca ttgctgtcgt ttcatccaag tactctcctc ttaaatcaat
    22801 aaggttagtt ccatgtgcag tggctatccc tgtttttaat gtgacagcaa gtagcaacgt
    22861 actaatatct gaataaccta ctatccattt tggttgtaga gcatcaaaat cgacaaaatc
    22921 gagaatctca atcaataatt ctcctcccca agtcggaaag atcatttgga tattttcatc
    22981 ttgcatcatt tgattgaatt catctgctcg ttttcttgct ggacctgatt tttccttatc
    23041 ttgcgtccaa agcgtctttc cagtaactac ttggaaagat ttttcttcca ttctctttaa
    23101 agctgattcg agtaacgaat ggtgttcctc tgatacgcct gaggatggtg cagtaacccc
    23161 aatcgttgca tttctttcta ataatggata acttatcatg ttgcttcacc tccaagtatg
    23221 cactatttta cttggttaat tgtttttttc gtttgccggc atcaaaaata tcggcatctc
    23281 aagtagctgg atgattttgt ttaagtcaac cgtttggatg accatcgttt gatctggtct
    23341 acctggtgca aaaacaagtt tttcatttga taagagctct tcatcaataa taatcggaat
    23401 ctgtttttca taaccaaacg gagaaacagc gccctgcttt tgtcccgttt gttcttccat
    23461 gcgttctgat gaaacaatag aaagcctttt accgacgatc ttccctaatg ctttgaaatc
    23521 cgtttgtttc gtagtaaaag tcagatatac gtagttatta tcttttttat cttttaagaa
    23581 taagcttttg gtctctgtac ctgtaaatcc ttgttctttc tttattacca aagcatcttc
    23641 atttgtataa atggctcgat gatgatacaa ctcaaaatat atattttcgt gtaagaattt
    23701 ctttgccaag tcaatcattt ttatgtctct tttctatttt attatttgag acatcttatc
    23761 atataaatat agcggttaca acattacttg tgttttgttc gttttttata cataactatt
    23821 gtttttctgg taaaataaat caaaccactt aatggaggcg ttttagaatg gaaaaatttc
    23881 agccgatcat caatcaaatc aaagaaaaag aacatcaaca aaagatcaaa gacctttttg
    23941 ctaagataac agaaacgtat ccccagctag acacaactgt aaaatggaac caacctatgt
    24001 ttactgacca tggtaccttt attattgcat ttagttttgc taaaaatcat ttttctatcg
    24061 caccggaaaa agcagcgatt cgtgcccttg aaaaaaatat ccaagaagca ggctacgtat
    24121 atacggataa cgtcatcaaa gttccttgga aaagtgtaat caactgggaa ttgattgaac
    24181 aattgatttc atttaatatt gaagataaaa aaggtcatga taaattttgg cgataaagct
    24241 ttatacgaat aaacctttta ctggcgagga aactattcat caccttatac aggttttgtt
    24301 caatcctatc ctttttatca tccctggtta aacacttaat tgacaaagta tctgctattt
    24361 ttataaggag tctttcttgt gctgaaaaaa atcactgatt gaatggcttt gaattttcta
    24421 cttagtaaaa ttattttttc agcaattttc ctgcaaaact tttgaataag gaaaaaatac
    24481 gagaaaatat cagtgatctt tcataatact gcccattatt ttcaggtata tttaaatata
    24541 atatcacttt aggagagaac gaatttcttt agagaaataa aagttagaat tttctgactt
    24601 gatttttaca atgaccttaa ttaaaatcgt tctttctaca tttcgtgatt aagcaaatat
    24661 caactaagtc agtagaacca ttcacatagg agggtgaaca ttgaaagatt tttactcagt
    24721 aaatgaatta gccgaacaat taggtgttac tacacgttct atcagaaatt atcttcatga
    24781 aggaaaacta aaaggaacaa aggttggcgg gcaatggaaa ttttctgaac gtaatctttt
    24841 tgagttccta tacggagatc aagcagagga agcagcaaaa gaaatgcagc gattcatgct
    24901 aaatgcacca atcacgatgc gtttcaacct tcaatatcgt gattttacag caatcaatca
    24961 attccgagaa caattagtcc agtaccataa cgatgtttac gcaaataaaa aagaccgtct
    25021 tttacaatac gatctttata aagacaatca tgcggagata ctaatcggtg gtaacttcaa
    25081 ttatgtcgta aactttagtc aatggatcaa tgaaaaatta ttgatccaga cagatatttc
    25141 ccttgtatct taaacaatta aaaagcgcta gaaattccag agatgttgga aattctagcg
    25201 ctattttttt ataagtactt actgtttggt tcaaacaaat atttttttaa taaatgaaat
    25261 tttaccatct ttatcctcaa ataaagaccg tgaccatgct tcctactacg atcagcaata
    25321 atccgataat cgttaatttt ttttcttttg gtgtcttatt ttcatgcagg atgtacatac
    25381 cgcctaatgt agagataact acgtttagct gtgtaatgat atatgcagta gcaaccccat
    25441 tttcatttgc tgaaaaaata taagccaatg ctgacacact aaagatggct ccaacgatcg
    25501 ttgctttcca actcttgtct tcagaaaatg cggttggttt acggaaaatc acataaatca
    25561 ctgcccctaa aaagacaccg atcatttgcg gaaagaaaat ggaaagtccg cttgcatcaa
    25621 ctagtttagg caatgcactg tatacccaat aaccaatact tgttgatgct aatagactaa
    25681 ttccttttgt gataccgcct ttttttccag gatcatcact gattgccgtt aaagcagaac
    25741 caaatacaag aagaatgatt gctgctgctc caatgatttt ccccatactt ccagaccatt
    25801 ctccaaaagc gaagacacca atcaacgagg ttccgactaa ctgtaatgca gtcgaaattg
    25861 gcatcgtttt agaaacacca atcaagttga aagatgtata ctgtcctgtt tgtccaataa
    25921 cccaaaatgc accagaaagt aaactaatca aaaatgtagt cactgaaata ccagctggag
    25981 aagcgaataa ttgaacgagt aagccgacaa gcaccgctcc aataccagtt cctaatatct
    26041 catttgttgg tctgccacca atctttttca aaatcagtgg ctggatcccc cagccaactg
    26101 ccgggatcaa tgcaatcaat aaacccattt ttattcaccc ttatcctttt ccaccttgga
    26161 aagaaggata taaagtcatc ccaccatctg caaatagtgt aatacctgta acataactgg
    26221 attcgtctga agccaaccat gcagctgtcg ccgctatttc ttttggttca cctacgcgtc
    26281 ctagtgggat catactttcc aagagttctt tttgttcagg atcatcaaat tttgccgcat
    26341 taataggtgt acggatagca ccagggccta tactattgat tctgattccc ttcggtgcat
    26401 actccattgc taccgtttcg gtaaataatt ttaccccgcc ttttgaagca gcgtaatgag
    26461 caaacgttgg ccatgggatc tgttcatgaa cagaagacat attgatgata tttccttttt
    26521 tattattctc tgtaaagtaa tttaaagccg ctttcgttcc gataaaaacg ccagtcaaat
    26581 tgacttttaa cactctttcc caatcttcaa ggctaagttc atgggttgga tgctgatttt
    26641 ccatcccagc attattaacc caaacgtcca gtgtcccaaa attttctaaa gccgtatcaa
    26701 gtaaacgctg tattccttct tcagaactga catctgcttg tacagagact gcttttccgc
    26761 ctgcctcttc gattgctttg actgcttttt ctgctccttc tttatccgag ttatagttga
    26821 caactacatt cattttttct ttcccgaatc gttgagcaat cgctgttcca atcccctttg
    26881 agccaccagt tactactgcg actttgtttt ctaattcctt gtacatagta cccactcctt
    26941 tttcatacct aaacctgtta ttacggataa cttttatttc cgccttaaag tgagtgtaca
    27001 ccaagatata tagtctaaag caaatgatac gctctagcaa tcgttttcat gaattgctag
    27061 tgtcctttta tttctataaa gaaagaggtt gtgacagaag tggtcagctt caagaaattt
    27121 cggcttattt ccgaagaagc tacttctgaa aaaccattta tttggaaaaa aaggctgtga
    27181 caagactttt gtcacagccc ctttcctggg cttatttatc acccatttta ttgtaattgc
    27241 tagttataca taaacaagag attttatgca taatgtttta ttgctgagaa aaatattcag
    27301 ctgttgcttg ttcatcctcc ttgagttgtt caatcaattc ctctacacta gaaaatttca
    27361 cttgatctct taaaaattga ttccagcgta ccgcgacatg ttcaccatag atatcttgat
    27421 taaagtccaa aatatacaac tctacagtca gctcccgtcc ttcaccgaat gtatcattat
    27481 gtccaattga acccatggct ggataccatg tttccccaat ttttatttcc gacacataaa
    27541 caccttcttt aggcaaatga accgtgctct ttactttgac atttgctgta gggaatccta
    27601 gtagtctgcc tcgtgcatcg ccatggacaa ctaccccttc tacctcatat gtgcaaccta
    27661 atagttttgc tgcttctttt acttgtccgc tgtctagtaa tccacgaata cgggtagagc
    27721 tgattttttc accttgttct tcttctttag aaactgtgac gattttgaat cttcctttgg
    27781 catattcagg aaaatgagcg acatctgcaa tgtcttttgg tccatacgta taatcaaaac
    27841 cggaaacagc atattttgca tgtaacccta cgatgtattg atcaacaaat tcctgcggtg
    27901 ctaaatgagc aaaagaagaa gtaaaatcaa cttcatataa ataatctata cccaaagcgg
    27961 ccattttttc ttctttttgc ttaaggctag tcaaatattt cacgctgcta ggatcgatct
    28021 ttttaaagac aatagatgga tgctgattga aagtcatcaa tgctaatttc aatccttctt
    28081 tttgtgcaat ttccatacct gtctttatga ctttctggtg tccgatatgc acgccgtcga
    28141 aaaatcccag cactaaaacg acatcgtctt ctggaatttg ttctgattgg taaggatgtc
    28201 tgatcttgat gatattcatt cgttattcct catttctcaa tactttacta ggttttaatt
    28261 tgtttttttc tttcgggttt ggctgataaa tactgacaac ttttccttta taaaacaaag
    28321 caatttcttc tgacggcatt tctgggagcg caaatacagt ataatcaagt ctcataccgt
    28381 tttttacttt ctgccatact tcatcagtaa tatctactcg tttgaaccgt tccactcctt
    28441 tttctattgg cagcaaacaa tcatcgattg tcccattttt cacagcttga gctacttctt
    28501 ctaatgtcag agcatccttc tgggacatac cggcacttgc tgttcgggtc agatcagaca
    28561 tgtgcgcagg gtaaccaagt ttcttgcctg tatctacagc taatgtgcgg acataggttc
    28621 ctttcccgca ttctacttcg aagcgccaag aaatggttcc tgtcacttcg tctcttgtca
    28681 attcacttgt ccggataaaa cggtaaatct gagcctttct aacaggacgc tccactgttt
    28741 cattattgcg ggcatattca tataaccgct taccgttgac ttttaccgct gagtacattg
    28801 gtggtatctg ggtgatctca ccaataaatg aagccatcac ttcatctatt tttttttcag
    28861 ataaagacat atctactggt tttgtttcta cccgttctcc ggatcgatct tccgtcgttg
    28921 tactgaaacc tagagttatc tcgcctacat agattttccc agaatctgtc aaatattcga
    28981 taacttttgt ggcttttcca atacaaatgg gcaacacacc gtctacgtct gggtcaagcg
    29041 tacccccatg tccgattttt ttcgtatgta agatttttct taatttgaat acgcaatcat
    29101 gacttgtcat tccgcgttct ttccataaag gtaataaccc gtccatgtct tttctccatt
    29161 tcatttttga tttaactgaa ttattataac acattgcatc aattactgac gaatttgaca
    29221 tcataatgaa cggtttttat ttttcggcaa taaaaacgta acaaaattca tgctcacgta
    29281 aatagaaatc atgttatgct tttttaaagg agggaataga atggaagatt ttttctttgc
    29341 accatttgat tggatttatg ggtggcttac aggtaaatag tttggttttc acttcccaaa
    29401 aacgaaaaaa aagactggcc attcttccag tcttttttcc gtttttttta tttatttttt
    29461 cagtttctta atcaatgtaa aaaattctat tttgcgggat cgattttatc attttattgg
    29521 tcaagatttt tccatttcca atccaatact tctggcagat caataccatt ttcacgaata
    29581 tagttttgat gttcttgtaa tttctgatcc atttttttcg caaaatcttc tgcttgactt
    29641 cctttgattt ttaaagctgc gtcttttgcc aaatgataac gatcaagttc atttactaca
    29701 cgcatgtcaa atggtgtcgt gatatctcca ttttctttgt agccatgaat cattaaatga
    29761 tggttatgac gatcaaagaa aatcgtgcgg accaatgttt cataaccgtg gaaagcaaat
    29821 aagatcggtt tgtcttttgt aaaatattga tcaaattctt catcgctcaa cccacgcgga
    29881 tcttgacttg gatgacgtaa tttcaataaa tctacgacat tgatgaaccg aatttttagt
    29941 tttgggaatt cttccagcag caaagttaca gctgctaatg cttctaagtt agattccgtt
    30001 cctgcagcag caatgaccaa ttcaggttcc tcctcttttg ctgtcgaagc ccaatcaatg
    30061 attttcaagc cttcattcac taagacggct gcttcttctg ctgagtaaaa ttgagcacgc
    30121 ggatgtttgg aagagatgat caaattgatt ttttctgacg agcggaatgc tttatccatg
    30181 actgcgagca atgtatttgc atccgcaggc agatattcac ggatgaactc cgccttcttt
    30241 tctgccaaat gtgtcaatat tcctggatct tggtggctat atccattgtg atcttgctgg
    30301 aagactgttg agcttgcaat gagatttagc gaaggataat catttcgcca agaaaggtca
    30361 tgtgatttcc gcatccattt gaagtgctga gtcaacatag agtcaaccac tcgcaagaat
    30421 gattcgtaac ttgcaaaaaa ccatgccgtc cagtcagaac gtacccttct aagaaccctt
    30481 catcttggtg ttccgataat tgactgtcga tgacgcgacc agatggcgaa agccattcat
    30541 cattttctgg ttcgattttt tccatccatt ggcgatttgt cgttttgaaa acttgattca
    30601 atcggtttga ttttgtttca tctggtccaa atatacggaa attttctgga tttttctcaa
    30661 tgatctcgcg aacgaattta ccaagttcgg tcatatcttc tgctttaacg gagcctggtt
    30721 tttcaaattg caaagtatat tttttccaat ctggcataat aagcggtctt ggatcgattc
    30781 caccattggt gataggattt tttgccattc tttggtcacc agtaggcgcg atttctctga
    30841 tttcttctaa aatacgtcct tgtgcatcaa ataatttttc tggttcatag gatttcagcc
    30901 aacggagtaa agcatctgca tgatccatat gttcttgatc tacaggaatc ggtacttggt
    30961 gtgctcggaa ggttccttca attggttccc cgtcccattc ttttggaccg gtccatcctt
    31021 ttggtgtgcg tacgatcaat actggccatt ttggcatcac gacatctgtt gctgtcttca
    31081 ggcgagcttc tttttggatg gatttaattt tctcgattgc ttgatccatt ttttcagcca
    31141 taacaggatt taatttttct gaatcatttc cttcaataaa gaaaggttcc cagccaagtc
    31201 cgttaaagta atttgctaat tctccatctg atttacgtgc caagatcgtt gggttggcta
    31261 tttttgcacc atttaaatga aggatcggta aaacagctcc atctatcact ggattgataa
    31321 agacatttga gaaccagctt ccagctaaag gaccggtttc tgcttcacca tcaccaatca
    31381 cgacagcaga gattacttca ggattgtcta atacagctcc gactgcatgt gaaagagagt
    31441 atccaagctc tccgccttca tggatagaac ctggtgtttc tggtgctgca tgagaagcaa
    31501 tgcctccagg aaatgaaaat cgtttgaata atttttgcat tcctgtctca tcttccgtta
    31561 cttctggata gatctctgtg taacttccat ctaaataagc attcgatacc atgacttgtc
    31621 cgccgtgtcc tggcccttca atataaaaca tgttcaaatc atatttattg atgactcggt
    31681 tcaaatggac ataaataaaa ttttggccag gaatcgttcc ccaatgaccg attggatgtt
    31741 ttttgacatc ttcgggtttc agtgtacgtc tcagtaaggg gttatcttta agataaagtt
    31801 gcccaacaga aagataatta gcagcacgcc accaagccgt cattttatca aagtattctt
    31861 tactagaata atccatacat aacactcctt ttcattatta ctcttattct agcgcagata
    31921 ctcccaattg aaacctaata agcacttctg ttcatttgtt tggattttat atctagccaa
    31981 atgaacaggt ataaaaaacc acgaaatttt tcctttcgct gacgtttttt acattgatcc
    32041 aaaaaacttg tcgttatcac aatggctgtt ccgcagttca tttcgctcct catcatgcat
    32101 aatttgctga atgacgctgg gccagttaac acattgctgg aaaactgggg ctggatcgag
    32161 caattccttt cctgattgat ccgttttatg taaaagtctc tgttatcttt gtcaatatgt
    32221 gaattggtat cccagctact atgctaattt ctacagggat tatccaaaat ttggatcgtg
    32281 accaaatcga agcggcgtaa tcggaaatat caataacttc aacgtgattt ttcttttaac
    32341 tgtcaacgga ccgacaaact caaactttta tggtgcaggt tccactgatc ttctagttac
    32401 ttggctatac ctgactgtca ctaaaataga ttacaatcta gcttccgtta tcggtatctt
    32461 gatctttatc tatatgcaaa aatttatata ctactagaaa aaagaaagtc gaatttttta
    32521 cttttctttt tctctttttt ggttagctga cacgccgcaa gactaaagtc atggaactct
    32581 taggtaatac gtcttaatga aaacaaaaaa atcccgcaac ccctgatttc acaggatttg
    32641 cgggagtttt tgattagtct ttgttcaagt cgcgaagcaa ttcatcgata tggttgccat
    32701 agacaactga ttcatcaagt tcaaagaaca attcaggtgt cttataaata cttagattgt
    32761 gccctaactc tcgacgaatc aatcctgatg ctttattcaa tccatcttgt gctgttttct
    32821 tatctgatgc taagtcagat aaaatgctgt aatagatcgt tgcttgctgt aagtcccccg
    32881 taactttcac atctgtgatc gttacgttct ccacacgagg gtcacggacc tttttgcgca
    32941 aaatatcatt gacttctttt aagatttctt gaccgactcg gcggtcacgg tagttagcca
    33001 taatgattgg cctcctttta tcagttttta gtcatttttg acttcttcca tgataaatcc
    33061 ttcaattacg tcatctactt tgatgtcatt gaatttttca atcattgcac cacattcata
    33121 acccattttg acttctttca cgtcatcttt gaatcgtttc agacttgcaa gttggccttc
    33181 atagattacg attccgtcac ggattacacg gacaccgcta tctctacgaa tatatccttc
    33241 tgttacatag gcacctgcaa tcgtaccaac tttagaaact ttgaaggttt cacgaacgat
    33301 catttgaccg gtgatttttt cttcaaattc agggtctagc atccctttca tcgcagtttc
    33361 gatttcttcg atggctttat agatgatacg gtgaagacga atatcgactt cttcagtatc
    33421 agcttgcact tttgcctgcg gtgtaggacg aacgttgaaa ccgatgataa tagcgttgct
    33481 ggctgctgct aaggttacat cactttcatt gattgctccg acagctgaat ggacgatttt
    33541 tacacggaca ccttccacat caatcttctt caatgatgca gccagtgctt ctgctgaacc
    33601 ttgtacatct gctttgatga ttacgttaac ttctttcaat tcgccttctt tcaggctttc
    33661 aaataagtta tccaaagtca cacggcttgt ggcagcacgg ttttctaata atgcacgttt
    33721 cgcgcgttct tcacccgctg cacgtgctgt cttttcgtct tcgaagacta cgaaacggtc
    33781 acctgcttga ggtacatcat tcaagccagt gatttctact ggcgttgcag gtcctgcttc
    33841 tttatcgcga cggccaagat cgtttgtcat tacacggaca cgtccgtaag tattaccgac
    33901 aacgattggg tcaccaacat gaagtgttcc ttcttggaca agtaaggttg acacaggacc
    33961 tttaccttta tcaagacgtg cttcgatcac tgttccgatt gcgcgttgtg ttggatctgc
    34021 ttttaaatct tctacttctg cgactaacag gatcatttcc agcaattctt cgatgttttg
    34081 gccgaatttc gctgagatct caacaaagat cgtttctcca ccccatgctt caggaattaa
    34141 ctcatactca cttaattctt gcataacatg ttgagggttt gcacctggtt tatcaatttt
    34201 atttacagcg acgatgattg gaacgcctgc agctttggca tggttgattg cttcaactgt
    34261 ttgtggcatg acgccatcat ctgcagcaac aactaagatc gtgatatctg tgatacttgc
    34321 tccacgtgca cgcatacttg taaaggccgc atgtcctggt gtatccaaga aagtgattgg
    34381 tttaccatca atatcgatct ggtaggcacc gatatgctgt gtgattccgc cggcttcgcc
    34441 gcttgttaca cgtgaatggc gtaatgtatc caataaagtt gttttcccat ggtctacgtg
    34501 tcccataatc gttacgactg gcggacgtga gactaattta tctggatcga cttcttctgc
    34561 ctcgaagaat ttatcgatat cagcaatgtc aacttggact ttttcttgtg gttccatgcc
    34621 atagtccgtc gctaacagtt caatcgtatc tttatccagt gcttggtttt gattgaccat
    34681 gacaccaagc ataaataatt ttttaatgat ttctgctggc tcacgatgaa tttttttcgc
    34741 aatatctgct acgttcatac cttcagtata ctctaataca tctggcaatt cacggaattt
    34801 gcgtggtggt acagctggtt tagttgattg ttgctgtttg ccttttttac cttttttatt
    34861 ataacgatta cggttattat tattaaattt gccgcgattg ttattgtttg gtttgttgtt
    34921 attgttagta cggttttgat tgccgccttg gctcgttcct tgacgatttt ggctgctggt
    34981 atttcccgta ttattttggt ttgttgttgg tttttttcct tgattcactt gaccgctccc
    35041 ttgaccgcga tcttgataac tgcggttatt tttatttttt tgttgattgt tcgttgtttc
    35101 ttttttacgt tgatcgttcg gctgttgatt ggctggtttt ctgcttgctt gttgtgcagc
    35161 ttgttgtttc gtgcttgggt ttttgaacgc ttgttgcaat ttcttctcat cattgctagt
    35221 aatcgcaccc atatggtttt tcacatcgat gccaagttgt tgtgcttttt ccacgacgtc
    35281 tttactagat tttttgagtt cttttgctaa ttcatagatt cttttgttgc ccatgcaatc
    35341 accttcctaa ccttcaatta gctccttggt cttcttcgca aatccggcat ccattattcc
    35401 gaataccttg cgaggttttc cgatcatctg cgtgatttct gcttcagaaa atagctcaaa
    35461 gcaaggaact tcataatatg aactcttatc ttttatcttt tttcttgtat tctcgcttgc
    35521 atcggttgcc acaaacacca attttgcttt ttgtttgcgg atttcagcaa tggtcagttc
    35581 ttcacccgtg attagttttc ccgcgcgcat cgctagaccg atgagattca tggctttttg
    35641 ccgattaact gtattcattt tccaaataac tctttacgtg ctttttggtg agtgacatag
    35701 tcaagaagtt cttgataaaa ctcatctgtt aatgttgttt cgagtactcg atcgagaatt
    35761 tttttatccc aagcttgttg tacttcttcc ggctcaagtg agacatacgc tcctcgtcca
    35821 ggcatttttc cagttggatc gatcgatact tccccttctt ttgaacgggt gattcggacc
    35881 atctcttttt taggtttcat ttcacctgaa accacggatt tgcgtaaagg aattttcctt
    35941 tgtttcatct ctttgcctcc ttactaaagt taagcttctg gtttttcttc gaccgtttca
    36001 ttgttgaatg caattgtttc atattcatcg tctgttaaat ctgactgaac gattgcttca
    36061 tcatgcagtt cttctgtttc tttttgttgt tcttgatttt cataaaattc cgtcatgtca
    36121 gattctgatt tgatatcgat tttatggtta gtcaatttag cagctaaacg tgcgttttgt
    36181 ccgcgtttac cgattgctag cgataattgg tagtctggaa cgacaactgt gcaggccttt
    36241 ggatttgtct catcgaagat cacatccatg acttgtgcag gattcaatgc atttgcaatg
    36301 aatacagctg gatcttcatt ccattcgacg atatccatgt tttcgccttt taattcattg
    36361 acgattgctt gaactcgttg tccctttggc ccgacacatg taccgactgc atcgatattt
    36421 ggatcatttg agcgaactgc cacttttgaa cgatcgccag cttcacgggc gatgctgaca
    36481 atttcaacga ttccatcata gacttctggt acttcttgct caaataagcg gcgcaatagg
    36541 tctggatggc tgcggctaac aaatacttgc ggacctttag acgtattttc tactcgggaa
    36601 acataaactt tgattcgatc atgtggttga taaaattcat ttggcatttg atcttgttta
    36661 gaaagaactg cctcaatttt accaagattg acataaatat aacgtttatc ctggcgttcg
    36721 acgattcctt gcatgatgtc tttttcataa gcactgaatt cgttataaat aatcgttctt
    36781 tctgcttcac gtacacgctg taaaataact tgtttagccg tttgcgcagc gatccgccca
    36841 aaatcttttg gtgttacttc aaaacggatc gtatcaccga tctcatatgc tggattgatt
    36901 aaaagtgcat ctttcaatga gacttccaac tgtgaatcca tcacttcttc cgttacttct
    36961 tttaccgcat agacatggat ctttcctttt ttctgatcaa attccacttc gacgttttgt
    37021 gcttggccat agtgacgttt gtatgcagaa accaatgctg cttctaaagc atcgatcacg
    37081 atttcttttg agatcccttt ttcagcttct aaagcgtcta acgcatttaa catttcttta
    37141 ctcatttttt ctgattcctc tccgtgatta aaattggata gctaagcgag cttttgcaat
    37201 attttttcgg tcaaaagtca attctttttc tcgtgttttt atgcgtattt tcaatgtaag
    37261 ctgttcagca tcaaatgatt gaagaaatcc ttcatattgt ttttcgccat ctactggttg
    37321 gtataaggag acatggacat aatcaccaag tgccttttca tagtcgcttt cttttttcaa
    37381 tggccgctct gctcccgggg aggatacctc caggaaataa gcttgaggaa tcggatctgg
    37441 atctgctgca tcaagttttt cactcagttt ctcactgaca aaggcgcatt cttcgatatc
    37501 gataccgcct tctttgtcaa taaatactcg taagaaccag ctttttcctt cttttacaaa
    37561 ttcgacttcg acaagttcaa aattttgttc atctaaaatc ggtgtcacca tttctgtgac
    37621 tgtttcaacg acgctactca aaagtttcgc ctccttaaaa aattaagtgc gtaattccat
    37681 taaaaagagt gagcgaaaaa tccgctcact cacagttagt atcattacct ataagaacta
    37741 taccatactc tgcttaaaat tacaagcaga caggaaaaca gatgcttata gcatatcgaa
    37801 taacgataat tgattttcat ctggtagatc tttcaatacg ccattgtcgt tcatatattc
    37861 gatcaatgtt tttgaaactt taccgcgggt ggcaagatct tctttggata aaaatggacc
    37921 gtcttttctt gcttcaacga tttgttttgc cacgttggtt cccaaacttg ggacagctct
    37981 aaatggtgcg atcaacgtat caccttcaat aacaaagtta acggcatccg atttatacaa
    38041 atcaatcatt ccaaatttga atcctcgttc cagcatttca ttggctaact ccagcactgt
    38101 cagttgattc ttttctttta cggaagcatc taatcctttg tccgtgattt ctttcattgc
    38161 ttgtttcaca gcatcttttc ctttgcacat ggagactaga tcaaagtcgt ctgcacgtac
    38221 agaaaagtat gcacagtaat acaaaatagg gaaataaacc ttgaaataag cgacacgaag
    38281 agccatcaat acgtaagctg cagcatgggc tttcggaaac atatatttga tttttgaaca
    38341 agaatcgata taccagtcgg gcacattatt ttctttcatc gccgatagat aggtttctcg
    38401 caattcatca gggatcttgt tccattgtcc tttacgaaca gtttccatga ttttaaatgc
    38461 catcccgcta tctaatccag catggatcaa ataaaccata atatcatcac gacagccgat
    38521 tacttccgcc agtgtcgcat ctcctcgtcg aatcaattct tccgcatttc ctaaccatac
    38581 gtctgtacca tgagatagtc cggaaatttg cagtagttct gcaaaagttg taggatgcgt
    38641 ttcttctagc atccctcgaa caaaacgagt gccgaattct ggaataccta atgtccctgt
    38701 tttggaataa atttgttcct gacttactcc aagtacttca ggaccggcaa atatccgcat
    38761 cacttccggg tcatccgtag ggatcgtttg tggatcgatc cctgataaat cttgaagcat
    38821 ccgaataaca gttgggtcat catgccctag aatatctaat ttcaatacat tatcgtgaat
    38881 cgagtgaaaa tcaaaatgag tcgttttcca ttccgaattt tgatcgtctg ctggatattg
    38941 gatcggcgta aaatcataga catccatata atcgggaata acgatgatcc cccctggatg
    39001 ctggccggtt gtccgtttga ctccagtagc gccttttgct aatctgtcga cttctgcact
    39061 tcgaaactgc agattattgt ccctttcgta tccttttaca tagccatatg ctgttttgtc
    39121 ggcgactgta ccaatcgttc cggcacggta aacatagtct tcgccaaaca atactttcgt
    39181 atagttatgg gcttctgctt gataatcacc tgagaagttc aaatcaatat cgggcacttt
    39241 gtctccatgg aatcctaaaa atgtctcaaa tggaatatca tgaccgtctt tgtttaagcg
    39301 tgcaccacat tttggacatt gtttttctgg catgtcaaat ccagaaccat acgtaccatc
    39361 ttcaaaaaac tcggaatatt ggcactctgg acaataataa tgaggggcta acggattaac
    39421 ttcagtgatt cctgtcatcg tcgcaacaaa gctagagcca acagagccac gtgaacctac
    39481 tagatagcca tcttcattac ttttatgcac tagtttttgg gcgatcagat aaataaccga
    39541 gaagccatta ccattaatag aattcaactc tttttttaat cgtttttgaa tgatctcagg
    39601 taacggatct ccgtacattt gttttgcttt tgtgtaactc aattctgata tttcatcttc
    39661 tgaacctgga atcttcggtg tataaagttc atctttgact ggaatcactt cttcgcagat
    39721 atctgcgatt ttattcgtat tttctactac gatctctttc gctgtttctt cccctaaaaa
    39781 gtgaaatgca gttagcatct catcggttgt tcggaaatgg acatccggca aactatgacg
    39841 attcaacgga ttcgctccgc ccatagaatt gatcaaaatt tttcggtaaa tggcatcttc
    39901 ttcgttcaga taatgtacat tacctgttgc aacaacgatt ttatccaaac tttttccgat
    39961 ttctaccaaa ttttggataa tttcttccaa atcatgttca ttttttacca attcttgctc
    40021 gatcaaaggc gcatagaccg cttttggcat aacttcaata taatcgtaga attttgctcg
    40081 gtttcttgcc tcttctaccc ctttttgcat catggcttcg aatatttctc ccttatcaca
    40141 agctgagccg atcaatagat tttcacgcat ctttttcaat tgggagcgtg gtattcgtgg
    40201 gacgcgttcg aagtattcga cattcgacat tgaaatcagt ttgaacaaat ctttcagtcc
    40261 tgcctgattt tttgctaaaa tcgttacatg gaaaggtcga gcccttttgt aagaatctcc
    40321 ttctccgata tgctcattta gctgatcatg ataaagcatg ttatgattgt ccattgcctc
    40381 tttcacaaag atccatgcta agtgaccagt tgcttcagca tcatagattg ctcggtgatg
    40441 ctgttccaag ctgacaccaa attttttaga taacacacct aatccgaaac gtttgaattg
    40501 aggatacaga tatctagcta attccaacgt atcaatgact ggattggccg cttcaggaat
    40561 accatacctt gcgtagctag tattcaagaa ccccatatca aaagccgcgt tgtgggctac
    40621 caaaattgta tcttttgaaa attcaaggaa catccgcaat acttcttctt ccgactttga
    40681 tcctcgaacc attccatccg tgataccagt cagatctacc gttgttcgtg acaaaggatg
    40741 tcctggatcg ataaattcat caaagctttc gatcacattt cctttataca ttttgactgc
    40801 ggctagctcg atgatcgtgt catatactgc agacaatcct gtcgtttcca cgtcaaatac
    40861 gacatatgtg gcttcactca atgcttcatg tgcatcatta taagcaattg ggacaccatc
    40921 atctacgaca ttcgcttcca cgccgtataa gattttcaca cctgcttttt ttccagcact
    40981 atgtgcttcc ggaaaggctt gcgcaccacc gtggtctgta atggcgatag ctcggtgtcc
    41041 ccatttccct gcttgtgcca caagatcaga gatgctgttt gttgcatcca tcgtactcat
    41101 attgctatga acatgaagct ctactcgttt ttccccttca ggagcataat ctttgcgagg
    41161 tgtatgtttg acttctatga tatcttgcgc attcatgacc aaatcacgga caaacgtatc
    41221 ttcttgaata cttcctcgta cctttaacca gctaccgaca ctgatcgcat caaatacttg
    41281 ttcatctttt tcgccgttcg agaatttttt gacgataaat gatgaagtat aatctgtgat
    41341 tttcaaagtc aagatcttgc gttttgaacg tagttctctg acttctttgt cgaatacgta
    41401 cccctcaagt gtgactcttc gttcttcttc aacgatactg atcattggtg tcgttggttc
    41461 atcggctgga atatttcgtc ctagctggat gtggatgggt ccttcaagag ctggcgattg
    41521 ctcttttctt tcctttttct tttgttcgtg gacaactaga ctttcagctg cttgcttcat
    41581 aaaggcttct gcctgttctt gtttgcgttc ttcaaaaagt ttcaatactc gttccgcttg
    41641 ctgctcatcc acttctggtt cgatacgaaa ttttgggaat ccgtaactga cgaacaactc
    41701 ttctactaat ggcaagtatt gttgcttcaa ataagaaata gctcctgtac tgtcgattgg
    41761 caagatgact ttacgatctt ttatcacagg tacctgcgtt ttcaatactt gctgtgctag
    41821 tggtgtatcg cattgctgat tttccaaagc ttgggcccag taatcttgca agagctgttc
    41881 atcgaatgtc tggtcatctg ctaagatatt cagtttgact tgtgcaatat ctttaaaagc
    41941 gatagtcaga tgctgagtca atgaccgata tagcataata ggcaaaattt tggaaaaatg
    42001 cagcgtaaat tcccataaac gcgatttacg atggaccact acactatcca tttcaccagc
    42061 agtaagcagt ggatgatttt tttctgcttc ctctagttgg atttgttcca acagtttttc
    42121 aaataaatct cgtttttctg acaaagatat acgccctttc tgatgagaaa caatgcaatt
    42181 gatcgcatct tatcctcttc tttttcagta ccttttagta tactcgtttt ttctgagttt
    42241 tacattaaaa aattggaact gcgattcaaa tcgcagttcc aattttaaaa gcgaatcatc
    42301 agattgtcaa aaacagctga ttcagctatt tttattttct gtgttttaac gcttattatt
    42361 cgccttggtt caagaggatt ggtaaagtat tcaccaattc ttctttacgt acttcaacca
    42421 tttcgccagt tttcttgatt ttcacttcta cgattccatc cactgctttt ttaccgacag
    42481 tgattctgat tggacagcca atcaaatcag aatccgcgaa tttcactcct gcgcgttcat
    42541 ttctgtcatc aaccagtact tcatagccag cttttgtcat cgcttcttct agttcattcg
    42601 tcaggtttgt ttggtattcg tcttttagat tcatttggac gatatgcaaa tcaaatggcg
    42661 caattccttt tggccagttg attccttgtt catctgaatg ttgttctacg attgctgata
    42721 ataaacgact tacaccgata ccataacagc ccataatcac aaatttttct cgtccatttt
    42781 cgtctagtac agttgctccc atagattcac tgtaacgagt gccgattttg aagatatgtc
    42841 cgatttcgat tcctcgagta aaggcaagaa caccattgtt gtctggtgaa ggatctcctt
    42901 cttgtacaaa acgaagatct tcataagaaa gtacagtgaa atcgcgttct ggattcacat
    42961 ttttatagtg gaatcctgtt tcgttcgctc cagtaatggc attcgctaaa tcttggacat
    43021 aacggtctgc atatactttt acgtcatctg aaacaccgac tggtccgaca gaaccaaact
    43081 cagcacctag atatttttgt gcttcttctt ctgttgcttc ttctaaaaag tcagcagata
    43141 aaaagttttt cagttttacg tcattgactt catggtctcc gcgtaccaaa acaaggacag
    43201 gttgttcatc cgcaatgaac aatacagact tgatgatttt ttgaggttca acagaaaaga
    43261 aatctgctac ttcgtcaatt gattttacgt taggtgtagc tactttctcc aattcaagct
    43321 gtgtttcatg cgattttttt gatacatagt agcttgtagc catctccaag tttgcagcat
    43381 aatcactttc agtcgaataa cagatcgtat cctccccgat ttctgagatc gccatgaatt
    43441 cttttgagtc tttcccgccc attgcgccac cgtctccgat aatcgagcga aattctaagc
    43501 cacaacgctt gaatacttcg gtgtaggctt tttcgtaatc tttatatgtc tcgtccaaac
    43561 tttcttccgt tgcatggaaa gaatacgcat ctttcatgat aaactctctt ccgcgaagca
    43621 aaccgaagcg aggtcgtttt tcgtcacgat atttaggttg gatttgataa agatttaaag
    43681 gtaatttctt atatgaattg atttcattac gcatcaaatc agtaaaagtt tcttcgtgag
    43741 ttggtccaag gatcattttt cgatcattgc ggtctttgaa acgatacaag tttggtccat
    43801 atgtttcgta acgcccggat tcttcccaaa gttctgctgg caagatggca ggcatcagca
    43861 tttctaccgc tccgattttt tcaaattctt cccgcataat gcgtttcagt ttttccaata
    43921 cacgatttgc taatggcaga tatgaataaa tacccgctga tacttggcgg atatatccag
    43981 ctcttagcaa gatttgatgg cttaatactt ctgcatcatt tggaacttcg cgtaatgttg
    44041 gaatcaacat ttttgattgt ctcattctat atactccttt atttcctcaa aatagttatc
    44101 gtttgttatt ataccctatt tgtcaacttt ttctagaaaa agaatcgttg aatatcgttc
    44161 catgtaacta gcaccatcaa caacattaaa aatccaaagc cagctaatgt caatattcct
    44221 tctttttctt gacttaatgg tttcccgcga atcccttcaa aaatattcaa gactaatttc
    44281 ccgccatcta aggcaggaat cggaagcaga ttgacgattc cgagattcat tgaaagaagc
    44341 gccatcaaac taataacagt tgttacacct tgatttgctg cttctgaaga caattggtac
    44401 atcatgacag gtccgcctaa tttatctaaa ctgaaacctg taaatagtga tcctaaggct
    44461 ttgaaaattt ccaatgaacc gctgaaagct tgacgcgtcc ctccaatgat cttatccata
    44521 aaacctgtat tcattggggc ttttatacca agttggccaa ctttttcgcc atttgactct
    44581 acagatttcg gtgtcacgtc gacagattgc acctgacctt ctcgttcgat cttaaagtct
    44641 aatgttttat ccggattttt cgtaatgact gttgtcagat cattccatga atggatttct
    44701 tttccgtcca cactgactac ctcatcattt tcttttaagc ctgcttctgc cgcagctcca
    44761 ttaggcatga tctctcctac gcgattagtg ttcgtcactt gaacaccacc ttgcataaat
    44821 gccagaatga tgaataacag gattgccaaa ataaagttat tcatgggtcc agcaaagttg
    44881 gtcagcatac gctgccacaa tttagccgat tggaactgta cgtcttttgg cgcaattctg
    44941 atttctgttc cgtcgttttc aataatcgtc gcatcgtgat caacagggta ggttactact
    45001 tctgtttcgt ctccattcac ataaccagtg atagtcagct catcttctaa atcataacgg
    45061 ctcaattcca tcgggatagc atttgtcaat tggattttct tacttaaatt tatcttctct
    45121 acgatgccgt cagaatttag taaaagagaa agaggcattc ctggtgccat ttctgtttca
    45181 tcatccccat tgcctgccat tcgaacataa ccgccaatag gtaataggcg aagcgtatat
    45241 gttgtcccgt cttttgcttg atgcccataa attttcggac ccataccgat agcaaattcg
    45301 cgaacgagga ttcctgatcg tttcgcaaag aagaaatgac caaactcatg aacaatcact
    45361 aatataccaa aaacgatgat aaatgtcaga atcgttttca tagctttttt ctcctttact
    45421 tgttttttgt gttttttata aaacaacgat aaaacactat aattttacca tagtatacca
    45481 aagacaccaa tagtatcaat ataatgaaaa ataaaaacct gcgtctttta tgaaattcac
    45541 aaagaaacgc aggtatactt actaaataat gccaaataaa tgcatgatag gaaatacaaa
    45601 cagcaaactg tcgaaacggt ctaagattcc accatggcct ggtaagatat ttcccgagtc
    45661 tttcacatca taatgacgtt tgattgcaga ttcgaccaaa tcaccaaatt gtccgactgc
    45721 tgaaaaaata atcgtcatca gaagcatgac aaacatacca tgattaaata gttcttttgc
    45781 tgggtatagc aataaataaa gaaatgcgac tacaacagca ctaccaatac caccgagcgc
    45841 accttcaatc gttttgttgg gcgaaatatc aggacttaac ttatgctgac cataacgtcg
    45901 accaaccata tatgctccga tatcagttgc ccaaacaata aatagaccaa atatcaaaac
    45961 agccaagctt tctgttcgtg cattgacaaa attctggaaa cctattccca catacaagct
    46021 gacaagcaca ggaaaacctg cttcatcaat cgtatacgta tttttagaaa taactgatgt
    46081 tcctaaaaga atcataacta taagataaaa taacataaat gtacttacat tctctggaag
    46141 aaagaaaaac catctttctt ttggcaaaac aagtaacact gcaccaacgg cggataaaac
    46201 tccttcaaaa cttaagagtg tcaatccttt catccgaaac agctcgtaaa ctcctattac
    46261 tgctaagatt gctgctgtaa gctcaaccgc tatgcctccg atccatataa tcggaataaa
    46321 caagactagc gccacggctg ctgtgaccac acgttgtttc atgactgatc ccctttctca
    46381 tcttctgttt tttttacacc gccgaatcga cggtctcgat tttgataaga ggcgattgct
    46441 tcttcaagat gcgcaccatc aaaatcaggc caaagcgctt ttgtaaaata cagctcacta
    46501 tatgcgatct gccataacag aaaattacta attcgctctt ctccacttgt acggatcatc
    46561 agctcaggat cttgtaactc tttaggcaag aaacctgtca ttaaatgctt agcaatcaat
    46621 tcatcatcga tttcttctgc gtgtatttct ccttttgcta cttcttcggc aatttcttgg
    46681 acagcagtca cgatctctgc tctgcttcca taattcaaag caaaattcaa taccattcca
    46741 gtattgtttt ttgtttgctc aattgcacgt cttacagcat cttgcgtatg ttctggcaat
    46801 acgttttcat aacccatgac atgaactttg acattttctt taatcaattc tggtacgaac
    46861 gtatcaaaga agtcgacagg tagttgcatg agaaaactta cttcatcttt tggtcgcttc
    46921 cagttttcag tcgaaaaggc ataaagcgtc aacactttca ctccaagcct tgatgctttt
    46981 tttgtgactt tctttactgt ttccatgcct tctttatggc cagcaactcg tggcaaacga
    47041 cggttttgcg cccaacgacc attgccgtcc atgatgatgg caatgtgctg aggaattggt
    47101 ccatcggtat taaattgaaa ttcgcttttt tcttgaatat atttgttttt ttgcggaaaa
    47161 aaacgtaaca ttctttttcc tcctatactt aaaagattcc cactatctta agtattatag
    47221 caatatctaa ctgtttttcc tatgaaatca ttgttttttt atttaaaaac tgaataattt
    47281 tttctttttt taatttttaa ataaaagaaa tataaataaa aacagaggaa gcggaatgat
    47341 ccgcccctct gtttttatga ttttattaaa cttccaataa ttctttttct ttatcagcag
    47401 cgatcttatc tacttctttg atgctgttat ctgtcaatgt ttgtacgtct ttttctaatc
    47461 cgcgcaaatc atcttcggta atatcaccat ttttttgttg ttttttatat tcatcgatcg
    47521 catcacgacg gatgttacga atcgcgattt ttgcattttc tgcttctttt ttaacatctt
    47581 tagctaattc ttttctgcgt tcttctgtca gttgcgggat aactaagcga atgacatttc
    47641 catcattggt tggactgatt ccgatatcac ttgccataat agctttttca acatcttgaa
    47701 gaatgctctt gtcaaaaggt gtgatcatta aaacacgtgc ttctggaatt tggattgatg
    47761 ccatttggtt caatggtgtt ggcgcaccgt agtagttcac agtaatacgg tccaaaaggc
    47821 tagcgttcgc acggcctgcg cggatttgcc caagttcacg ttgaagattt tgtgctgctt
    47881 ttttcatttt ttcttttgct tctgtcataa ttgcatctgc catttttatt tcccccttac
    47941 agttgttccg atattttcgc ctaagattgc acggcgaata tttccgtgtt catttaaatt
    48001 gaagacaagc agtggaatat cattatccat gcttagtgaa cttgcagttg aatccatgac
    48061 ttgtaatcct ttggcaataa cttccagatg agtcagttct tcaaatttta ctgcatttgc
    48121 atctactttc ggatcagcag aataaacacc gtctacattg tttttagcca tcaggataac
    48181 atctgcgccg atttctgccg cgcgtaatgc tgctgttgtg tctgtcgaga agtacgggtt
    48241 gccggtaccg cctgcaaaga taacgatccg tcctttttct aaatgacgtt ctgctttacg
    48301 gcgaatatat ggctctgcga tttgacgcat ttcaatcgaa gtttgcacgc gtgtcggtac
    48361 acccacgttt tccaacgtat cctgtaaagc taaggcattc ataactgtag ctaacatacc
    48421 catgtaatca gcttgagcac gttccatgcc catttgtgct ccgatttgtc cgcgccagat
    48481 atttccgccg cccacaacga ttgccatttc aacgcccagc tcgtgaactt ctttgatttc
    48541 ttggatgatt tctttgatta ctggtggttt gattccaaat cctgcgtccc cagctaaagc
    48601 ttctccactc aattttaaga ctacacgctg atatttcggt gtgaccatgt tcattcctcc
    48661 aatattttct attgccattt taccatactt agatgatttc gacactctaa gactggtttt
    48721 tcttgttttg cttaaaaaaa gggagcgcac aaaccgtgcg ttcccgtctg ttattcaaca
    48781 gaattatttt ttcacttggc tcataacttc ttctacaaag ttatcttcgc gtttttcgat
    48841 accttcgcca acttcgaaac gtacgaatgt tttaacagtt gcgccttttg atgcaacgta
    48901 tttttcaaca gtcatatcag gatctttaac gaatggttgg tccaccaaag cgatttctgc
    48961 tttgaatttc ttcaagcgtc cttctaccat tttttcaacg atattcgctg gtttgccttc
    49021 gttcaatgct tgttctgtaa gaacagtttt ttcatgttct aattcagctt ctggaatttg
    49081 tgattcgttt acataacgag gattgatagc tgctacgtgc atagctacgt ctcttgcaac
    49141 tgtttcgtca gttgttccat ctagaacagt caatacggca atacgtccgc ccatatgcaa
    49201 gtatccacca aatgcagcat tgtcgtcttt ttctacaact tcaaagcgac ggaagctgat
    49261 tttttctccg ataacttgag ttgcttcgat caagtcagat tcaattgtac ctttatctgt
    49321 tttgattttc attgcagctt ccatgtctgc tggtttgttt tcagcaacaa gttctgcaat
    49381 ttcttttact aaatcttgga acatttcgtt tttagaaaca aagtctgttt ctgagtttac
    49441 ttcaacgatt gctgcagtgt tacctttcac agcaactgaa gccaatcctt cagctgcaat
    49501 gcggtcattt ttcttcgcag cctttgccat tcctttttca cgtaaaagat caactgcttt
    49561 ttccatgtcg ccttctactt caactaatgc ttttttcgca tccatcattc ctacgccagt
    49621 catttcgcgt agttctttta ccattttagc tgtaacgtct gccatgttta actcctcctg
    49681 tgtgtttttc tttttaaaaa aagctgcttc aaaggagagt gaggcttgtc gcccagcctt
    49741 tgaaacagct ccatcattca aaattattct gctgaagaat tgtcgccttc aacaacatct
    49801 acgatttctt cgattgatgt tgctgtgttt tcttctgtga aatcttcttc aactacttga
    49861 tcttcacctt ggtttccttc gatgaaagca tcagccattt ttgaagtaat caatttaacg
    49921 gcacgaattg catcgtcgtt tgaagggatt actacgtcga tttcatctgg atcgcagttt
    49981 gtatcaacca tagctacgat tgggatattt aatttgtgtg cttcttgaac agcaatacgt
    50041 tctttacgtg ggtcaacgat gtacattaca tctgggattc ttggcatatc agcgataccg
    50101 cctaagaatt tttcaagacg ttcacgttct ttgttcaaac cagcaacttc ttttttaggt
    50161 agaacttcaa aagttccatc ttcttccatt gcattgattt gtttcaaacg gctgatacgt
    50221 ttttggatag tatcccagtt tgtcaatgtt ccgcctaacc aacgatggtt aacgaagtat
    50281 tgtcctgcac gagttgcttc ttctttgatt gcttcttgtg cttgtttttt tgtacctacg
    50341 aataatgcta cgccgccttc ttcagcaacg ctcttcatgt aatcataagc tgcatctact
    50401 aatttaactg ttttttgcaa gtcaatgatg tagattccgt ttctttctgt gaagatatat
    50461 ttcttcattt ttggattcca gcgacgagtt tggtgaccaa agtgtacgcc ggcttctagt
    50521 aattgtttca tagaaattac tgccatgttt gtttcctccg atttggtttt atttttcctc
    50581 ttcttatctt ctaccttgcc ggcaaacttt ttcaagcacc taccgacaat ccaataagaa
    50641 tgtggatttg ctgatgcata aagcaccctc agctattata cagacaaaag atccgtatcg
    50701 caagagcaaa tatacttttc tgctcaacat tcaatagttt acctgaaaga taaaaagaat
    50761 tcaagaaaaa cagtagattt ctctttgttt ctttattatc ctttttccat aaaataattt
    50821 taggtataaa agacgaatat tattgggcaa tccttctttt ttttgttatg atacatgtga
    50881 aatctttcgt aaaggagaaa gaaaatgcgc aaagctcaaa gacatttgct gattaaacaa
    50941 gtcattgaag aattcccgat ccgtacgcaa gaagaactat taaacaaact tgggcattat
    51001 ggcgttaccg ccacgcaggc aacgatttct cgagatatcc gtgatctaaa aatcgtgaag
    51061 gcacctgatg aaaatggcgt ttcccgcttc gtattgtttc gcgaaaaagg aactcctgag
    51121 actaggactg aggaagagga tcggctggtt caaatgattg aagacattgt attgaaagtc
    51181 gaacgagtcc actttttgac gatcgtcaat accttgccag acaatgctca tttatttgca
    51241 tctgttttag atgagatcaa acctccctct attgtcagta caattgctgg attcgatacg
    51301 atcatggtca tctcggaaaa tgaggaggac gcaaaacgag tagaagaatt tcttcaccat
    51361 ccaactgaag tatcactttt ttaatcagag cacgtattcc taatatggaa tgcgtgtttt
    51421 tttattttca atattttcct tattgaataa acctttacac tctttacaaa aatacatcat
    51481 tttttattca aatttttcaa caccttgatt gaatcacaat aatcatcatt tatattggat
    51541 gttaacaaga gcagcttctt gctctttgtg tatttcaaaa aagaaatgaa aggaaatcat
    51601 atgtataaat tattaacttc tggaccattg acgacttctg aaacagtgaa aaatgctatg
    51661 ctgatcgatc attgtacttg ggatcaagaa tacaaagaaa ttacacaatg gataagaaaa
    51721 aaattattgg atcttgctca agtatcggaa ggaatataca caacggtctt aatgcaaggt
    51781 agcagctcct tcggggtaga atcggtatta agttctgtga tcaggccaga agatactgta
    51841 ctgatttgtt caaacggcgc atatagacaa cgaatgatca acatgtgcga atgtctgaaa
    51901 ctgaactata ccgtttatga ggtatcggaa catcaaatcc tccaagctca tgtgattaca
    51961 cagctgattg aagagaatcc gtctatctcc gcactagcaa tggtccatag cgagactact
    52021 tccggtattt tgaataattt ggaagagatt gctgctgtca cacaagaaag agatcttttg
    52081 tttatagtgg acgcgatgtc aagctttggt gggataccga tttgtgtagc cgaactaggg
    52141 attgattttt tgatttccag ctcaaacaaa tgtattcaag gtgttccagg cttttctttt
    52201 gtacttgcta ataaagcgga actggaaaaa cgaaaaaatg ttagccgaag tttgtcactt
    52261 gatctatatg accagtaccg cgtgatggaa aacgagaatg gcaaatggcg tttcacttcc
    52321 cctacccata cggttttggc ttttcaacaa gcgctgaagg aactagaggc agaaggagga
    52381 atcgaaactc gatattcacg ttatctcgcc aataatcatg tgctacgaca aaaaatgaca
    52441 gagatggggt tccagccttt cattcaagaa tatcaggggc cattcatcac ctcttttctt
    52501 taccctaagg actggcgatt tgattttaat catttttatc agtatttaaa gcaaaatgga
    52561 tttgtgatct atcccgggaa aatcagcgat catgaatgtt ttcgtatcgg aaatattggc
    52621 gagatctatc cggaagatat tttggaactg acagcaatta tcaaagacta taaggagaac
    52681 gttaatgatt aaaactgtaa tttttgattg ggcaggaaca actgtggact ttggctgtat
    52741 ggctcctgtc cacgctttta gaaatgcttt tctagaaaaa ggaatccaac tgactgacaa
    52801 agaaatccgc taaccgatgg gaaaattaaa atgggatcat atccaacagc ttctttccct
    52861 cccttctgtc aaaaaacaat ggatagctat ttatggacaa ctacctcagg aaaaagaggt
    52921 ggaggaattg tatcaacaat ttgaacatta tctgtttaaa gatttggtca agcattctac
    52981 cttgaaaccc gacacattgg aaacgatcga acggttgaga aacgctggga tcaatattgg
    53041 ttccacgaat ggatttaatg ctcctatgat gacaatcgta gcagaaaccg caaaaaaaga
    53101 aaggtattca ccagacttca tggcaacttt tgaagacgtc gaagggtatg gtcgaccgtt
    53161 tccttatatg atccataaaa acatgcagta cttcaaaaac aagtcggttg atgaagtaat
    53221 caaagtcgga gatacggtct cagatatcca ggaagggaaa aatgccggag tgttgacagt
    53281 aggtgtaatt gaaggtagtt cgctaatggg gatttcttat gatgagtacc aaaaattaga
    53341 gatggggaaa aagatcgttt aaaacagtct gttgctctta gattccaaca agccggcgct
    53401 gatatttgtg taaacaattt aaaagagtta acagaataca ttttgtacgc tgacatgaat
    53461 ccagaatgac ttttatacaa aataagaggt tgtgaaaaag ctgtcctgta tcaagtaata
    53521 aaaacagcca agcaaaaata gctcctcata tttttcgttt ggttaggctt attaccgcag
    53581 atgcaagctt ttgaacaccg tttattcgaa aaaaaaaagg gagctgtgac acgacttttg
    53641 tcacagtccc cttatttgca aacaaacagt gtttaagaga caacctctcc actaaacggt
    53701 gttcattcag ctgactctcg gtatttgctc aaaaaacgat aaaatttgaa aagctatttt
    53761 ctcttttgtt tctctaatac tcggatcaga acgctgattt cacattctct ttttcttaca
    53821 tcttatctgg tgcatgaagt cctagcaaac gaaggtcttc tttcaataat acagtcactg
    53881 cataaactag agctaagcgt gcttcttttt gttcatcatc agctaaaatc ttcgtatgag
    53941 catagtattt gttgaatgct tgtgctaatt tgattgcatg tttcgcaatc actgacggtt
    54001 cgtatttttc cccagcagac aagaccgttt cagggtattt ttgaactaat ttaaccactt
    54061 cccagctggt atcgtcattc aatgcatagt ctgctgtttc tgaagggaca aatcctgctt
    54121 tttccaacag gctgactgca cgagcatgtg tatattgcac ataaggtcca gtttctcctt
    54181 caaatcgaac aacttcttcc aggttaaagt caaatgtatt cagtcgatcg tttttcaaat
    54241 cgtggaaaat gactgcccca accccaactt gtttagctac agcatctttg ttttccaaat
    54301 cagggttttt ctcgctgatt tgttctttag cagattggat tgcttcattt aatacttctt
    54361 ctaataagac gatctttcct ttacgagttg ataatttttt accaccttgc gtgatcaaac
    54421 caaatggaat atggtgcatg tcgtcagacc agtcaaagcc catttccttc aagacagctt
    54481 tcaactgttt aaaatgatag ctttgttcat tccctactac atatagagat tgtttgaagt
    54541 cgtaagtacg tttacggtac aatgcagcag ctaagtcacg tgtaatgtat agtgtcgcac
    54601 cgtctgactt cttaatcaac gctggattca ggtcataagc agataggtca acgatctctg
    54661 cacctttatc ctcgttcagc aaatgttttt cttctaaaag tttgacgatt tcatccatct
    54721 tgtcattgta gaaagcttca ccgttcaacg aatcgaaacg tacttccagc agatcataga
    54781 ttttattgaa ttctttcatc gattcatcac ggaaccattg ccataattga atagcctctt
    54841 tatcgccttc ttccagacgt ttgaaccaag cacgagcttc ttcatttaat tctggttctg
    54901 tttcagctac ttcatggaat tggacgtata aacgaagcaa ttcattgatt ggttctgctt
    54961 taacagcttc ttctgtaccc cattttttgt aagcgacgat cagttttcca aactgtgttc
    55021 cccagtcacc taaatggttg atgcggattg gctgataacc gattttttcc ataatgaaac
    55081 cgatcgaatt accgataact gtcgaacgca aatgtcccat tgagattggt ttggcaatat
    55141 taggagaaga catgtcgatt ggtactgttc cttgattccc gatgttgcta tccccataat
    55201 gttctttttc tttcactact gtttgcaaaa cttttttgct gataagttct ttattcatga
    55261 aaaagttcaa gtaaggtccg acaacttcga ttttttcaaa gttggcagaa tcgatttttt
    55321 ctgctaaatc tgcagcgatt tgctgtggcg cttttcggta aacttttgct aatgaaaagg
    55381 ctggaaatgc aacatctccg tgttcagctg attttggatt ttctagtaat tgctcgactt
    55441 gttccagtgt taaatcatct ttgacagcgt catagacagc ttttgcgaca agatctttat
    55501 tattcatctt tattcctcct aaagtgttcc cttgattgtt aaacaaaaaa aatctctagc
    55561 gacggcatac ttagtatgcc atcactagag acgagatttc ccgcggtacc actccaattg
    55621 tcctaaaaaa ggaccagctc catctgatat cggtagacga ccgtctgttt aaaacagaat
    55681 tctccaagtg cgcttcgttg tatcttcttc attcggcttc caccacttcc gaattcgcta
    55741 gccaagaatg atacaagtac tctcttgttc aacaaatctt agtcttatta aactttcttg
    55801 aattatatca gaaaaaaaaa cgaaaggcta gtcgtttcat aaaaaaacaa tccagatggc
    55861 ctaaaggaga agaaatacca cctggatagc tataaatcat ttcgtaaata cgaaagactt
    55921 aacaaattaa tcagctacga taatcgttcc ttcttcagaa gctaaaagat tctcgatatt
    55981 ttctaaagaa gtgatgattg ccttagcgtt tggttttgct tcaacaaatg caatagctgc
    56041 ttctactttc ggaagcatgc ttcctggagc gaattgcttt tcatcaatgt attgtttcat
    56101 ttctgaaaca gtaacagttt ctaatttctt ttgatctggt ttttggtaat tgacatacac
    56161 attgtctact cctgtcaata cgatcagcaa atccgcatcg atgatttcgg ctaatttttc
    56221 tgaagcaaaa tctttatcga ttacggcttc tcgtccttct aatccagtag ctgtttctac
    56281 aacaggaatc ccaccgccac caacagagac tgtgataact ccttgatcga ccagcgtttc
    56341 gatgacacgt gcttctttaa tcgagatggg tttaggggaa gcgactactt ttctccatcc
    56401 acgtccagca tcttctttga atgtcacagt ggagtcagca ttcatttgtt ctttggcttc
    56461 ttcttccgtg tagaatggac cgactggttt acttggattt ttgaatgaag gatcattttc
    56521 atccacaata acttgagtga ctaaagaaac cacatcttta tcgatccctt tttccttcag
    56581 tacttcgccc atggcgtttt gtaaccagta accgatagat ccttctgtca ttgcaacaca
    56641 tgtatctaaa ggcattgccg gtgttttctc agaatcagca gcttgctgct gaatcaatag
    56701 gttaccgact tgcggaccat ttccgtggga gatgatcaat tcatctcctt gttcgataaa
    56761 tttcactaaa tactttgctg tttccattaa cgcttcttgt tgggcttttg cacttgcatc
    56821 cgtagacaag atggcattgc cccctaaagc gacaactact tttcgtttgg ccatttcatt
    56881 cgtcctttct tcagttctac cgaattttct agataacaaa acgagccagc gttttgtgat
    56941 tttccctcaa tgctgactcg ttttttcgtg agatgaatgt ggttatgctt aaacgcgagg
    57001 gataaacaag ttacctaatg ttgctgccat gatcgctttg attgagtgca tacgattttc
    57061 tgcttggtca aattgacgag catatttgct gcggaagact tcatctgtta cttccatttc
    57121 agtgatgcca aagcgttctt tcatttgttc accgtaaaca gtgtttgtat catggaaagc
    57181 tggcaagcag tgcaagaaga tcaaacgatc tgtgttgtgt gttttttcta ccatttccat
    57241 attgatttgg taaggtttca acaatttgat acgttcttcg aatttatctt cttcacccat
    57301 tgatacccat acatcagaat aaaggacgtc tgctccgtct acacctttat caacatcgtc
    57361 ggtaatcatc aattgtgcac cggatttttc agcaaagcct tctgccattt tgacgatttc
    57421 ttcttcaggt tgtaattctt ttggtgcaac gatacgcata ttcgctccta aaattgcacc
    57481 tgtgactaat aaagagttag ccatattgtt tcgaccatct ccgcagtaag caacagtgat
    57541 accttctact gttccaaagt tttcttggat agttaaaaag tcagcgatca tttgtgttgg
    57601 atgccattca tcagtcaagc cattccaaac tggaacacca gagaattctg ctagttcctc
    57661 taccattttt tgactgaatc cacggaattc gattccgtca aacatacgtc ctagtacttt
    57721 agctgtatct tctgtggatt cttttttacc taattggata tcatttgcac ctagatattc
    57781 aggatgtgca cctagatcga tcgctgcagt agtaaatgca gaacgagtac gtgtagatgt
    57841 tttttcaaat aaaagcgcaa tattttttcc ttctagatag tgatgtggga taccacgttt
    57901 tttcaagtct ttcaagtgtt ctgaaaaatc gatcaaatat tgtaattctt cttttgtaaa
    57961 gtctttttct gctaataagc ttcttccttg gaatactgat tctttcatat taaacattct
    58021 cctttagatt gtttttattt aagattaaag aggaaatccc gacggcagct gacagtaaga
    58081 ctgccgtcag gaaacaaatt acttcaagtc ttcacggaca agtggttggc tcatgcagcg
    58141 tggaccacca cgacctcgtg acaattcact tgaattgatt tctaacactt tgatgccata
    58201 gctacgaagc aattcgttcg atacataatt tcggttataa gtgactacaa cacctggagc
    58261 gattgccaat gtgtttgatc catcattcca ttgttctcga ggtgcaacga tctcatctcc
    58321 attaccagtt gggatcagta caagatcatc taatccaaga gcagctttca tcgtttcgtg
    58381 taagttatct gaatgagtaa tcttgatatc atcaccatct ggttcgattg taaagacatc
    58441 catcttaccg tctttacttt gaattgctgg atggatagtg aatttatcgt gatctaccat
    58501 tgtaaatacg gtatccaaat gcatcattgc acggttgttc ggaattttga ttgccaacac
    58561 tttttcaaat cctgaatttt ttgcgaatag gtggcgtgct aatttttcta aagctttcgc
    58621 attagttcgt tgagaaatcc caacagctac tactttatcg cttaagatca attcgtctcc
    58681 gccttcgata tgatctggat tttcacgatc caaccatact tcgattcctt tatttgcaaa
    58741 tcttggatga tgtttcaaaa tatattctgt aaacatcgat tcacgacgac gtgcttcaaa
    58801 agtcatctta ttgactgtca tcccatttcc cattgatgcg gaagggtcgc gtgtaaagta
    58861 caagtttggc attgggtcca tgtaaaatgg atagtcatcg tctgctgaca gatcatatag
    58921 actgctagaa cgtacttcga tatcttttgt acgaacccca gccatgattt tatctaccat
    58981 ttcttgcgtt tccattgata gaaggaactc atgaagaccc tctcttacag cattcgatgc
    59041 aatatgagat tcatccaaca ttttattcaa gaattgttct ttgacattgc ctgcgtcaat
    59101 cgcttctgcc gctaattttt ccaagtaaag agtctcgacg ccttcatttt gcaatgtctt
    59161 cgcaaagttg tcatgttctt cttgagcaat cggaagatat ggaatatcat cgaacaacag
    59221 acgatccata atatctggtg tcaaattttc cacttcttgt ccaggccgtt tcagtaaaac
    59281 tgtctttaat ttccctattt cagagaaaac gtgaataggt ttatccatgt tgtgttgcct
    59341 ccttcttttt gattacatgt ataggatatc ctccttttgt aatcactttc ataattttgt
    59401 ctcattcaaa atgagacatt cctcacatta atattcgata attaaataat taaacgtttt
    59461 tctattttta agcgtaattt attcattttt tattctgtat acactttcaa aaaaatattt
    59521 attcattgaa aaaatttttt tgaataaatt aaaaaaataa attatattat cgttgttagc
    59581 gtttactata tgtattattg ttgtttttta tacacaaatc attcgcttca aaacaaatta
    59641 ttcaatacca ttgtatattt tttacataat aacaaattat atttgtaaag tattaaaact
    59701 tgtttctaat gttggtatgt taaaacttta caaattcttt aaaaaaagtg acaataaata
    59761 tagtgaacaa taaggagagg actttttaat gcgtgttaat aaaatcgatt ttcacttttc
    59821 aaaactcaga tatcaacctg attttgaaca tttctcggat gaagagttcc aacagatcaa
    59881 ggaacatact gttcttcgtt cttataaaaa aggacagatc cttttcgacg atggtgatcc
    59941 cagacaacgg ttgtatatct tgaccaaagg actcgttcgt ttagaacgtt atgatgaaag
    60001 tgcaacttat tactactatg actatgtgaa tacaaataac ctttttccta tgtcaggaat
    60061 gtttggagaa gagacctaca cttatacagc tcaagcgatg actgatattg aaacattcta
    60121 ccttcctgtt tcctactatg aaaaattagc acgaaaaaat cccgaacagt tgatctatat
    60181 gatacaaaaa atttctaaag tagttgaaat acatgaattg cgtatccaaa tcggattgac
    60241 ctctagcgcc tttgaccggg taaaacaaaa tttattcatt ttgaaagaag aattgggcgt
    60301 accaacaaaa gatggtcata tcaccattcc ttatccgatc accttaaaag aattagcagt
    60361 gaatagcggc acgacacgtg aaactgctgg acaagtaatc aaacaactac gtgattccgg
    60421 gctgttagat tatgacaaaa agcgttttac tttctgtaag acagctacta ctccagctat
    60481 gagagaataa cgcgaacaaa aataagcagt gaccctgata aatatcaggg tcactgctta
    60541 ttttcctccc taaaacttct gaaagatccg gcagttttag atcactggac aagactcaaa
    60601 gattttctat gtgtgtttca gttatgtaat attcactgtt tgcaaaaaat actgttagat
    60661 taactagatg aagcgtcttg tcctcatccg atctagatta ttcgatattc ctcgacaata
    60721 aacgattact cagtgagggc aatcagagga acggataatg ataaataagc tgtaaaaaat
    60781 agcaaaataa caataatgat taaaagtatg taaaaaatag ggctttgaca aaaacgtgtc
    60841 acagccctat ttcgattaaa cggtgtgtac ctgtcaactc ttcggtcaca agtcataatg
    60901 ttcataaaca tgaggagctg ttttttgaaa ttgttccttg tgaatcagag ttaaacgaca
    60961 ggcttacgaa ctcttgatta aacggcgttc aaaagcttgc atacgcggta ataagaacag
    61021 ccaggtcaaa aacatgagaa gccgtttttc ctgggctgtt cttattactt gatgcagggc
    61081 agctttttca caacctcttt attcagataa aaccaagctt ggatcagcat tcaactgata
    61141 gctagcaaaa tttctttttt gcatttccac atgtgctgct gctccaatca ttgcagcatt
    61201 atctccacaa agtcgaagag ggggaatcac tagttctacc tcagggagtt tagctgccaa
    61261 agcatcctgc aatccttcac gcaacccttg attggccgct acacctccag ctataatcag
    61321 ttgcttgact ggataatttt gacaagctcg aagtgtttta gtaatcaata catcgatcac
    61381 acttgcttga aagctagctg ctaaatcatt tttgtctaga tcttctccac gctgttgtgc
    61441 attatgcacc aaattgataa atgcactttt taatccgcta aaactgaaat cataattatc
    61501 ttcatggatc atcgctcgcg gaaaatggta attatctttt ccctgatgag ctagctgatc
    61561 gatttctttt ccgcttgggt aagaaagacc taatactctt ccaactttgt cataagcttc
    61621 tcctgctgcg tcatctcttg tctccccaat gatttcatat gatccatctt cttgcatata
    61681 gactaattct gtatgtcctc cgctaacaag aagtgccatc aatggaaact ggaatggttt
    61741 aaccagacgg gctgcataga tatgccctgc catatggttt acaggaataa gcggcaattg
    61801 gtgtgcccaa gcaaaagcct tagctgcaga aataccaatc agcaacgagc cgacaagtcc
    61861 tggtccataa gtgacagcga ctgccgataa atcttctgcc gacacaccag cttctaccag
    61921 tgcatcttcc aagcataagg tgatttgttc tacgtgatgg cggctagcta cttcaggtac
    61981 tacgccacca aaacgtttat gactgtttat ttgagaagca acgatgttag ataagatctc
    62041 tgttccattt ctaacgaccg ctacactcgt ttcatcacaa cttgattcaa tcgccagaat
    62101 caattcttca ttcatttcat cgtctccgtt tttaactttc tgctcataat gatcgcatct
    62161 tccgtcggat tgcgataata tgatttccgt ttacctaata tacgaaactt ttctgattca
    62221 taaagttttc ttgctgcttc attagataga cgtacttcta aaaaaacatg cagcgaatct
    62281 tttatttgtt ccgtaatcag taattgtaac aaatgccgtg catgcccttt tccttgttct
    62341 gaaactgcaa cagcaatatt tgtgatctcg acttcatcta ttactttcga gtatccaata
    62401 aagccacaga tctggttatc ttcagctaaa agcagataat cagagtgagg ctgttggatg
    62461 tctgccaaaa actgcatttt cgtccaaggt gaaccatgtg gataagcatt ttcgctaatc
    62521 atccatacgc attctgccaa gtacgcttca tcaaaatctt tttttctgca aatcaactaa
    62581 tctcactcat tttctaaaag ttttatcata tccaacgcat cttcttttgt ttcagtgtaa
    62641 tatctttttt tgatcgttgt tgcttgaaac cccaatttcc gataaagtct ttgtgcatct
    62701 tgattactca tacgcacttc taatgacatc gtctcacagc gattcattat agcaaagttc
    62761 tcgatttcgt caataagcag cgaaccgatt cgtttacgct gatatgccgg tcgaacggca
    62821 atattcgtga tatggcaatc taaaccgaac gctcttgaac cgataaaacc aatcattctt
    62881 ccattatcaa agatacctag atatagatga ggaagcggtg acttcaattc tgatataaag
    62941 gcactttttg tccatggcaa ttcgccatta tagacttctc gttcgacatc cagcagctct
    63001 ttgatatctt ctgtagtcaa ttctcttagt acgtaacgac gatcgatttg ttcgactgtt
    63061 ttttctgtat aaatcatttt atcttgaaaa aagcttctgg catacgctct aaattttttc
    63121 aacataactt tcgtctccag gtgtgtgcgt ctccaaccat ttttcttctg cttctactcg
    63181 ttttaaatag cgaggaagaa aagcttgttt ctctgcaact ggttcaacta aagcacctaa
    63241 ttgagccaca gttacaccac ttggaatatc ccatgctgga actgtattaa tcatcgcact
    63301 aggcaatatt tcctttattt cagagaagaa tttgtgacaa tcactcccga cgaaataaat
    63361 agcttcattc agcttttgta gttgtgtgaa caaatcagaa gcagaaatat gtacatcttc
    63421 aagtacagtt tctaatctat tttctttcca gcggtatgcc ccagcgtata cattttttct
    63481 tcgagcatca aacatgggca caataatatt atccacaccg atgcaattag ccgcgatggt
    63541 tttcagacta gatactccta ctagctcttt atctaatgta taagcaatcg tttttgctgt
    63601 cgttacacct atacgaagcc ctgtataaga accgggacca tcagaaaccg cgattcggtc
    63661 aatgtctttt ggacttattt gaagatctgc aaacaattgg tcgattgcag gcatcagtgt
    63721 tacactgtgg ttgcgtttga tatttgtttg tatttgtcca agaatttgtt cgtcttctac
    63781 cacaccgatc gccaaagttt ggtttgcagt atctattcct aatgtaatca tatatttgat
    63841 cctttctgct atgacattct cgccttccat tgtagcatac ttttttattc tgaggatgaa
    63901 aataccaaag gcaaaactag tacaataata catgattatc tgctggcggg caaattttgc
    63961 cccttcctga aacacaaaaa agctgcggta tcactccatt ttcccacagc ttttccatct
    64021 tttatttcgt tgattctcga ataatcaact ctgtttccac aataatcttt cttgaaaccg
    64081 gtgctttgga attacttaat tgaagaatcg tctccactgc tagctctccc atccattcgg
    64141 tataaacttt tacagtagaa agcgagggcg ttacatattt cgctacactg acatcattga
    64201 agcccatcac agaaatatct tctggtacca ctaaaccttt ttcttgaatc gctttcagtg
    64261 cgccaatcgc taatgcatca ttagctgcaa aaagcgcatc aggaacatgc ggattcgttt
    64321 ttaaatattg cttcactgct tgatatcctg actcgacaga aaaatctgct tcgataattg
    64381 gaccttcgtc gtagcctttt tctgccaaaa cttgttgaaa tgccataatt ctgggatctt
    64441 ttagccgctg atggtttttc ttcgtatatt ctgttccagc aagcatagcg atatgttgcg
    64501 ctttatggga gacaaagtgt tcaatgactt tttgaacact tgacttaaag tcgacaacta
    64561 gagagtcgat tccttgagaa gtgccgtcag aatctaccaa aagcaaggca ttttgggatc
    64621 ctttcatttc taataactga gcttcgtcga attttcctag tgcgatcgtt ccatctgccg
    64681 gaagatcact aatggaatcc cacgtttctt tcaataaagt aacgtttgct tcttctgcct
    64741 ttttttcgat tcctaggcga atagataaat aataaagatc ttcaagctct tccgtatcgt
    64801 cgtaccactg gatcaggcga agcgtttgct tagtatttgc tgcattttta cgatgtttcg
    64861 tataatttaa gcgttctgct gcttcaaaaa ttttttgctt tgtggctaag ccaacggaaa
    64921 gatcaggatc atagttgaga actcttgaaa cagtagcagg agaaactcct gccaactgcg
    64981 caatgtcttt aattgttgcc atttgtctct cctccttttt tacgtttata aaatcgcagt
    65041 aaatcgttca aacgctgcct gtcctttttc atctcgcttg aatactccag cgtcttccag
    65101 tacacgtgca aaaacctgac ctacagattt ttgtacgaca tcggtgaccg tatctttcgt
    65161 caaatcagga tgttcttttt ttaattgttc tgcccacgga cgatgatatt cagccatctg
    65221 gttttcttct cctaataaga aatgctctac ttctactagt tctggtttca aacgaggtgg
    65281 taaaacagca agccccatta cttcgatcaa cccaatgttc tcctttttga tatgttggac
    65341 atctttatgt ggatgaaaaa tcccatcagg atgttcttct gaaacattgt tgtctcgaag
    65401 gacaaggtcc aactcaaagt aattgtccct tcttcgtgca attggcgtaa tcgtatggtg
    65461 tggtgtacca tctgctgaaa aagctctgat agatactgtt tcatccgaat atgctttcca
    65521 tttttccaat actgagttag ctgcttcaat aagcaagttt ttctctgttg attgcaaacg
    65581 gatcacagac atcggccatt tcacgactcc tgcgatgact tgcggataat cttctagttt
    65641 gataagtttt tctatcggtg cttttgccat aggaaattca tgacgtcctg cctgataatg
    65701 atcatgagaa agaatcgatc ctccaacaat tggtaagtca gcattcgaac caacaaagta
    65761 atgaggcaag acttcagtaa tccgaagcag tctagcaaat gtttcctttg tgattttcat
    65821 cgggcggtgt tgttctgata aaatgatcga atgttcattg taataagcat aaggggaata
    65881 ttggaatccc cagctttcac cgtctagatt cattcgaata atccggtgat tggtgcgggc
    65941 tggatagttc aagcgacctc tatatccttc gttttccatg caaagcatgc aggtaggata
    66001 gtctactttt accgcctcgc gttctgctgc gatttgtttt ggatcttttt ctggcttaga
    66061 taaattgatt gtgatttcca gttcaccata ctccgactct gccggaaatt tgatgttttt
    66121 tgcgatggct cttgttttga tgtagtcatt tttcttactt aaattaaaga aatactcagt
    66181 tgcttcctct gggcttttcg aatagtgctg tgcaaagaat gcattgacga ctgaaggtgg
    66241 cggtgtgaga aaatccatta attgcgcttc aaaaatctct tgttctgctg gcaattctga
    66301 aagaacacca ttttctcttg ccttagcgac aagctgatcc aataagtcta cagattcttc
    66361 cttaactggt cttacttcaa tgctttctag agcatcttct cctaccatcc ctaaaagacg
    66421 attctgtaaa tataagcggt ccatttccat ccatccgcca gcttcgatcg caagtgtggc
    66481 aaaatcacaa atcgtttgac tgattgacat atctcattcc cctattcttc ataaccattt
    66541 ggatggctga catgccaatc ccatgctgtt ttgataatcg ctttgatatc tgtgtattca
    66601 ggtttccagc ccagaatctc tctcgctttt tcacttgaag cgactaatcg gctaggatct
    66661 ccagctcttc ttggtgctat ttctgctgga atttcttttc ctgtcacttc tctagctgct
    66721 tctagcattt ccttgactga gtatcctttg ctgctgccta aattgaagaa gttgctttca
    66781 tttccttctt tcaagtattc caaagctaaa atatgtgcag caatcaaatc ttctacttga
    66841 acataatctc tgatacatgt tccatctggt gtatcataat cgtctccata aacagccaag
    66901 gcttttcttt gaccaagagc tacttgtaaa atgattggga caagatgcgt ttctggtgta
    66961 tgatcttctc cgatagatgc atctgctttt gctccggcta cattgaagta gcgcaaagcg
    67021 acatagcgca tgccatatgc ttggtcacac cacttcatca ttttttccat catcaattta
    67081 ctttcaccat acggattttt aggattagct ggtgtatctt ctgtgattgg agactctttc
    67141 ggctctccat aagttgctgc agtagaagag aatacgattt tattcacgtt gaactcgtgc
    67201 atgacttcaa gtaagatttg cataccgtat acgttgttgt tgaaatacat caatggtttt
    67261 tcgacagatt ctcctactaa agagcttgca gcaaaatgga ttactccttc aatcggttcc
    67321 ttttcaaata cggaacgtag aaattcttta tcccggatgt ctccttcata aaaatgagca
    67381 tctggatgta ctgcttgttt gtgacctgtg agcaaattat ctaccacagc tacttgatac
    67441 cccttttgaa ctagctggtc tacagcgtgc gaaccgatat aaccggctcc gcctagtact
    67501 aaaattgtca taaaaaacac tcctttgatt agtaaaattg tgtttgttga ttctatataa
    67561 tttaaaaaac gaagtttact tttatggtga aaacaaacaa agtaaaattt cgtaaattca
    67621 tatggtaaat ttataataaa acatttagta aacattttca agggtttttt gcaaaggttt
    67681 acaaacaaac gtaaaactag cctttttttc tcttttgttc cataatagat ataacaaata
    67741 ataaatgagg tggattcaat gaaaaaattt gtatctggaa tattagtagg aagtctggca
    67801 acagccgctg ccgttgctgg tttggttgct tctgtgaaaa aaacagtgat cgatccaatt
    67861 gacgaaaaag aagcaatgat cgaagaaaac cgtaaaaaag caatgcgtaa acgcgtttct
    67921 cgttaataat tatttaaaaa tacgcatgaa gactttctaa aaaacagata agtcatcatg
    67981 cgtattttta tttgtcagtc aatataagtt gtgctatttt atctgcctgt ctcagattcc
    68041 atggatctgt ataaggtcta gctactgctg cagttagcca atccacacct tcaacaggta
    68101 ttccatagca ataaaagtca gactggattt cccctgaagc atcaatcacg cgattcgtac
    68161 ctcgctcaac atctatagct tctgaatgat aacttcctgt attatctgaa aatgaaaaag
    68221 ggcgaacaag tttgttttcc ttcaaatttt ttatgacagg attacttgaa cgagaaaagc
    68281 ttgtttgtgg caatcgagct tcaatcaaat agcgactgct gatttcttta tcttgtagag
    68341 aaataacata gcggttgtgc ttttgctgaa tatcaaatgg cggttcgatc aaatgaaaaa
    68401 tacccgcatc tatcagtgct gctaattctt tcgtccgaat gattggcgga ccgatcgtta
    68461 aaaagctatt tagatgagta aaccatcccc atagtatttc tttgtattcc ttagcagaaa
    68521 aaacgtgcca ttcaatagcc tgccggattg gatcacgcca gtcttttaat gcatcaaatg
    68581 ttgaagcaaa tgctcctgtg caattgcctt tttccgcttc ttttatctgc ccttcaataa
    68641 atattcggct agcttctgaa aagggctcat tctgataggc aagaggagtt tctaaatacg
    68701 accaatccca tctataaggg attagtgctg gatgctttcc gagacactcc tctgaagaga
    68761 gggagagaaa atcatgctca aaatttttct ttggaatcgg caagtgatat tcttcgatga
    68821 ttttcttgta ataaaacaac tcaacgtctt ttttcagata gtcaaaaaat gtttcgccag
    68881 tcaaaaatcc cgactgatgc cattgctcca ggttttcttt tgttagtaac cgtggccatg
    68941 ccattgctcc gccttgcttt tgatttcttc ctcgagggta ataagggagc ccccttcttg
    69001 atccactgta tacaatcggt tccttgcctg atggatgata gaccagtttt cccttttcgt
    69061 tctcgaagcg ccctcctctt gatactgtaa acaatccgac ataatcaaaa aaacttaagc
    69121 ctagacctct taaaaagaca ttttctttag gcggtatctt cgaaagatct acatctgcag
    69181 gattagaagg aagctgatac agtaaaacat ttttctttgc gtagtctacc cacactcttt
    69241 cttcttctgt ctcatcattt tcccagtgac cgcttgctaa aacaagctga tcgatagaat
    69301 agctttgctg atctgtctgt aaaagataac catcttttct tttgcttact ttttttacta
    69361 aagaataaac aaactgaata gaagctggaa attcttcttg caactttgag aaaaaccagc
    69421 gttgatagag tccgtataaa catcgagtag attgctgatc tttttccaga cgattgattt
    69481 cttctataat tagttgctta tttttggtta ccgtctgttc gatataatct gtagcaggtc
    69541 ctttactcca ttgaaacaag ttgggtccct gtgttaccaa tcctccactg gacaatgttt
    69601 catctgtaaa aagcgtcact tgttgagaaa cagaattcat taataactcc ggtggctgat
    69661 tcaaccgcca aactcgacct ccaggaccat tgggatcgaa aagaaaaagt tcaagagaat
    69721 gtctgtcctg attattatgg agaatccttt ctgctacact taatcctcta ggtccggcac
    69781 caatgatccc tattttcatt tgcatgcctc catttcgata aattttttca ataaaacagc
    69841 atggttctga tgttcatttt ttgcaccata aacaaaagta atgactggat gttctttcat
    69901 aagttgactg agtttaaaaa tagcttgctt cttttcttct tcgaaaatca attcttgctg
    69961 gtatttcttt gcaaatgaag caaatcgttc tggtacatgg tcaaaagttt tgcgtgcttc
    70021 attactaggt gcaatttctt tcaaccacag atctaactgc gctttttctt ttgaaattcc
    70081 tcgtggccag aatctatcca cgagtattct atagccatcc tctttttcag catcaaggta
    70141 aacacgtttt aatttgatca tagttgtttc cttctttcta ccttttcgct tagcttatat
    70201 atgtagataa tagcacaaaa taaaaaaaat gaacggcaca actatccatt gcgccgttca
    70261 tgtgatcttg gtcaaaatct aatgattgat tcggttttta aagctgtcat acaatcatct
    70321 gttttatact tttttacttt tgatttttcc agaccatccg tcatatccac ccttaagtaa
    70381 ataaatctct tgataacctg ctttacgtaa tttatttgct gtacggatgc tcaaactttt
    70441 cttttgatcg taaatataga caggctggtc ttttcgaata gatcctaatg aatctttcaa
    70501 aacagtgtaa gggatgtttc ttgcacctaa aatatgccca gcatcaaaca catctttttc
    70561 gcgaacatcg attacttgtg cttttctcat tccttctcga aattcttctt ctgtcaaagt
    70621 cgttgctgaa cgtttggcca ttactcgtag atagacttcc caaaggatga ttgcaagcac
    70681 aatcaatagc aaaatgatat taattaccca taaaaccatg taatgcctcc gtttttttaa
    70741 gcaaatttca aggctaatga ggcagcacca atgacaccag cttcattacc aagctctgct
    70801 aatttgattt ttgttgattc tcttacttgc gggaaagtaa attctttaaa atatttctct
    70861 acacggctac gtaaaaattc tcctgctgcc gatactcctc cacctaacac gatacttgac
    70921 ggatttaatg tattccccaa gtttccgcaa gctaaaccta agtagaagca tacgcgatca
    70981 acaaccatca atgcaaacgg atcgtcttct tgagccattt caaagatatc tttacttgtt
    71041 acttcttctc cgttgtctag cattgctttc agttttgaat cccctgcgta ttcttctgcc
    71101 aagaaacgac ctaggcgtac cacacctgta gcgctagata cagtttctaa acatccgcgt
    71161 ttaccgcaag tacattcgaa cccttcagga tccacagtga tatgtccgat ttctcctcca
    71221 gctccgctca cgccgtgaat caaatttccg ccagcaacga tacctccgcc aacacctgtt
    71281 cctagagtaa cgaatacaac gtctggatcg ttttctccag cacctttcca tcgttcacct
    71341 aaagcagcaa cattcgcgtc attatcgata gcgaatttga ttcctgttcc tgcctcgatc
    71401 agttttttca caaattgaac ttctgtccag tttaagttat acgcaccaat aaccgttcca
    71461 gcttcgctgt ccacgcttcc tggggtaccc atgccgattc cgataaagtc ttcggctttc
    71521 atattatata aattcaaacg atgattgatt gattcaatga tttcaggaac gatatgctta
    71581 ccatcatcca aaatattggt atcgatgctc catttttgct gaatctctcc ttctggtgtt
    71641 aaaattgcaa attttgctgt tgttccacct aaatcaatcc caataatctt cttgtccatt
    71701 acaaatttcc tttctttcgg ctttcttcaa ttcggtgctc tctttttaat atgcgccacg
    71761 ctgtcatgta tgtatcatga tcaatcaaac ggctatcata cagattacgc aattcgatag
    71821 tcattaattc aatgtcatag atgcgtgcac ccacatagat aaagatgcca aattttttga
    71881 acagctgctg tacatcatat aagctctcca tctttaagca cttccttcat attatacaag
    71941 taaaccatat ttttttaaac ccagtaaaat acatattaca aaaagaaata caaaaactag
    72001 tgtagaaaga atcctttggt gtatcgaata gcttgtctgt tgtttcggta gacccaaaac
    72061 attccctaac actaatccgc caattagccc accgacatgt ccccaaacat ctacagaggt
    72121 atccagaaga ccaaaaacaa atgtcaacac aataaataaa agaaaatgtc tgactagctg
    72181 ctggatcgct gggttatgtt taaaatgaaa ccctaagata aacaacgcac cgaacaaacc
    72241 gaatatcgaa gtacttgcac caccagacag aacattcgct tcgttaaaag caaagcttgc
    72301 tgtatttccc attatcccgc tgaacatata aatcaagaaa aaacgccaat ggccatagat
    72361 tgcctcgatt tgctgcccca taaaatacag tatcagtgag ttcattacga aatgcatcag
    72421 tccaaaatgg atgaagattg gtgtcactaa acgccaccat tcattgaagt gaacaagata
    72481 aggaccatac attccggcat aataagggat ctcaagtcgc ggaaataatt ccatcatgag
    72541 gaagaccgct gtctgtatcc ctaaaaaagc ataggtccat aacggtcgtc ttaaccatgc
    72601 acgcaatttt atttgctgtt gataattcat gaaaacctcc catttcattt tagtcaataa
    72661 acaattgttg gatcttctga tcaaagctct ccggttgcca ttgttcattc aattgttcac
    72721 gaaaaacaag gctacatgtt tttttatgaa aattatttaa ataccggtcg taataaccac
    72781 cgccaaaacc gattcgataa ccggctctat tgtagataat acctggtaca atgaggagat
    72841 cgatcatctc cggcaaatag agcttctctg attgtggctc aagaacacca aaactcgaac
    72901 gtacaagaac ggactgttca tccatttcat aaaacgccat ctgacgtttc ggcaaagttt
    72961 taggtacaac tattttcttt tgttcttttt ctgctcgttg gataaccggc tgtgtatcca
    73021 gttcaaattc attcgataaa gtcgtcccta tcacttttgc tgacttccag tactcgctgg
    73081 cgaatagctg tttatagatt cgctgttctt tttccttttt cttgccactt ttggccagat
    73141 ttttcagctt ttcgattcct ttccggcgta atcttacttt caattggtcc aaaaactcac
    73201 ccttccttct ctcataaaat ggtataggaa aaaaagaaaa atagcaatcg aactttcaaa
    73261 taaatgcata aatagaataa aaagaagacc tagaaatgat tggccttcct tttttaatga
    73321 atttcaactg ttcagcgcgt gtttttgtct gataaaaagt gcatacagaa aatatggcgc
    73381 accaaaaagg gcaatcaaaa ttcctgtagg tacttcccca cttggtagaa tcactctagc
    73441 aaccatatct gcactaagca gaaaaatgga accgaacaaa ccgctcagaa caaaggtcca
    73501 gttattttct ttacgtacga ctagcttcgc agcatgagga gctagtagtc ctacaaaaga
    73561 taaactacct gtcaccgcta cactaccgct tgccaaagca acagctaaca acaaaaggat
    73621 tttttgactt ttagccacgt taaggcctaa tccttgcgcg cgttcttgac caaatgatag
    73681 caatacaatc ctctgtgcat aaagtcctcc tagcggaatt aagataaccg cccatggaag
    73741 caatgcccaa acataaggcc agctcgcacc ccagattgat cccgctaacc atgcattcac
    73801 aaatccataa ttttccttag ataattggat cgtgcatagc aatgttaatg cagaaaggcc
    73861 ggcattaacg gcaataccgg acaataagat tcgattcata cccaaaaagc catttcgatc
    73921 ataggccgca agatagacac agcaagcagc taaaacacca cctagaaagg ctacaactag
    73981 caatagaaac ggcagcgaat agtgcgaaaa gaaacctaaa taaagcatca ctaaaaatcc
    74041 tgctccggca ttaatgccca atatactaga atctgccaat tcatttcttg ttactccttg
    74101 caagatataa ccagaaacgc caagacaagc tcctgctaat aaactgatca gtaatcgagg
    74161 aactcgaaat tctctaacaa tcagcgccaa agaagatgat tctttcccta tgaacgtggc
    74221 aaaaagctga tccaggtaaa taaaaggcgt accaatcatt aaactaccta tagacaggat
    74281 gacaagtaca aaaagcaaga aatagaacgt ccaatatatt tttttcaccg ttgttccctc
    74341 cttacttgta tcagtaaaaa cggaacgcca atcaatgcaa tgactaatcc aaaaggtgtt
    74401 tcaaaagggg gattgatcat cctcgctgta aaatccgcca acataaccaa tccaccgcca
    74461 actaaaaaag agacaggtag aacataacga tagtccgttc caaccattcc gcgaacaact
    74521 ggcggaacca acagcccaat aaatgaaaca ggtccgacta acgaaacggc aatggctgct
    74581 aacactgcaa ctagacagaa aacaatcaac cgcgttcgtt taggatgact tccaagagct
    74641 aatgcatgtg tttcactcaa atgaatcaaa gatattgctt ttcctaatga aaaagaaacc
    74701 aaaacagcaa gtatatataa aggaaacaat actgctaatt gtttccatgt gatattggca
    74761 gctccgccta caaaccaaaa agcaagatcc tgctgcagat taaagaattg ggtaagtgct
    74821 tggctgatag cagtaaaaaa agaactaata gctacgccag ctaaaatcag ctgtaaagga
    74881 ttcatgccca ttttcgaaaa ctgcaaaaaa ccaaatacga gcaaagttac agcaaaagaa
    74941 cctgccaatg acattagaaa cacagaaaaa tcagaagctt taggccaaaa agcaaaacta
    75001 agggccattg ccaacgaagc acccgcgttg attcctagta agcctgaatc tgctaaagga
    75061 tttcttgtca ctccttgcat caatgcaccg ctcaatgcaa aacaactccc tacaagaaat
    75121 gctcccgcca cacgaggcaa acgaatattt cgtatgattt ggtgactttg ttttgatcta
    75181 tcaaaatcaa acaacgcctg ccaaaaatct gctttttcca cagtcgctgc gccatttgaa
    75241 agagcaacaa aaaaaataat caaaagaaca aaacagacca aaagcaggag tctatttttc
    75301 ttcatagtcc tcataattga tcctcctgct cttttggcaa caaatcatag gttagaaaaa
    75361 ctggtttatt tgttcttgga agcgtgacaa tcgttgcatc aatctcaaat atttttttca
    75421 tacactcttt tgtgatcact tcttcaggtg taccttctgt gatcaactta ccgtttttca
    75481 ttgctaataa ataatctgaa aaacgtgaag catgattaat gtcatgaatc gacatcaaga
    75541 tcgttgtttg tttcatttga ttgatttcag tcaataactg taggatctct aattggtgtg
    75601 ccggatctaa aaatgttgtc ggttcatcca agatcaagat atctgtttcc tgagcaagcg
    75661 ccatagcgat ccagacacgc tgggtttgtc caccagacag cgttgcgata tcccgcatac
    75721 gaaatccagc tagacctgta gcatccaacg cccactcaat tgcttcatga tcttgcgtgt
    75781 ccatgccact gaacagtttt tgataagggt atcgtccgta agatactact tcttctactg
    75841 tcatacctgt agggtgttca ctagtttgtg ctaataatgc aatttttttt gcaagttctt
    75901 ttgaactgta tgtagagata tcagagttat tgacaatgat ctttcctgat ttcacaggta
    75961 gtatacgggt aaaacttttc aataaagtag attttccact tccatttggc ccaatcaaac
    76021 tagtgatttt cccttcagga atcgtaacag acatgttttc aatgattttt ttgttttcgt
    76081 agccggctgc aatgtcagct gctcttaatc tcgtcatttc acccatcctt tcgctgaaaa
    76141 tcattctcaa ttatgacgct gtttcaacat ttcgtcaagc gctactttca tatctatagc
    76201 caaatgaagc ggttgacagc gttcgaaata tcaggaataa taaccaatga gaaagattct
    76261 caattatgtt aggaggaaag aaatgaaatt aaaaacaaaa gtattcacat tatctagcat
    76321 attgctgctg gctggagtac tgagcgcttg ctccccctct tcagataaag aaacagctac
    76381 aactgccaat tcgacgactt catccaatag tactcataca gtcacagata cacttggaca
    76441 taaagtagag attccaaacg cgcccaaacg gatcatcggc agttacttag aagactatct
    76501 gattgcacta ggggaaaaac ctatcgccca gtggactgtt ggcagtggtt ccattcaaga
    76561 ttatctgcaa gatgatttaa aggatgtccc aacgatttct tatgaccttc cttatgagaa
    76621 agtgttaagc tttgagcctg atttgctgtt gatttcttct tccgctactg tcgaaggcgg
    76681 gaaatacgaa caatatagca aaatcgcgcc aacttatgtt gtaaaaaacg gaacagatgt
    76741 cacatgggaa gaacaactaa aagatgtcgg caaagctttg gcaaaagaaa aagaggcaga
    76801 aaaaatcatt tccgattatc aaaaatccat caagaaaact cgagaagaac tagcagataa
    76861 aatcgagaac aagacagctg cagtgttgtg ggtgaccaac aactcagcct ttatggtcag
    76921 caaaaatcgg tcaagtggaa gaatcgtata cgacgatctg gaatttggtg ttcctgatct
    76981 agtggaagag gtctccaaaa aagccacttc tgactggtct gctgtttcct ctgaaaagct
    77041 agctgaatta gatgctgact acatcatcct tgtgaacagt gacaaagatg ctgccatgtt
    77101 caatgaacca agctggaaga atctaaaagc agtgacagac aatcatgtac tgcaattcgg
    77161 acctgaatct agttggctat ataacggacc tattgccagt caggaaatgg tcaatgatat
    77221 caaagaaaaa ctaaattgat tttaactaaa aaaagcatct tcacgattag tcgtgagatg
    77281 ctttttttct tattaacaaa ctagacgcat agattttatt cttcttttga agcaacccta
    77341 ttttttactc tttcccattt ttgaaaacga tgggcatata gattttcttg atccgttatc
    77401 ccctcatact cctctataag ggcgaagtct gaaaaatcaa tattcccaat atacgtatcg
    77461 ccttcaaacg tgctatcgat caatgttcgc cagatccgac cagtgtaagg aagaagttct
    77521 tgaaaaatcc gactaccacc cgaaacatag atatcttctg agatcgtttg actatacgac
    77581 aaaagttcat cgatcgaatg cattacttcc gcattttctt tcgtgcgaaa atttggttgc
    77641 gttgtcaaca cgatgatatg gcgataagga agtgaaagat cccccattcc ttcataggtc
    77701 tttcttccca tcactaaaat tcgatccatt gtatgttcgc gaaagaaacg catatcattt
    77761 ggcaatcgcc atggtaacaa accatttttg ccgatcagac catttttatc ttgtgcccac
    77821 atggaaataa acatattatc cgctccttat gattttagat gttttgagat aaaaaaagtc
    77881 tcaattcttt gaccagcaag gaattgagaa ctttaaaaac attattttgt ttcacggtgc
    77941 aaagtaactt tgcgttcgcg tgggcaatat ttttgttttt ccaaacgatc aggattgtta
    78001 cgtttgtttt tgcttgttag atagttacgt tctttacaag aagtacactc taaagtgatg
    78061 tttacgcgca tgtttttccc tcccattttt acaagaatcc tctaagatga ctctcagact
    78121 tgattatctt accatgattt tttctagatt gctagtgttt ttcacgattt tgttaagtaa
    78181 aactacttga cgataaatac aacggtttta cttctcaaac aaaatctttt tctttttgta
    78241 taaataccct tacacttgtt tatatagatt atgtttttta ataaaggggg atactaatat
    78301 gccatggaac atgaaggact ttcctgcatc aatgaaaaac ttagataaat tgacaagaaa
    78361 aaaagcaatc gacatcgcaa atgcattatt agatgaaggg taccctgata accgtgcgat
    78421 cccaattgcc attgatcaag caaaaaaatg gtatgaagat gctagtgaat cagaaaaacg
    78481 aactttcgaa aaagaaaaaa atccaagcaa gacggatgaa cacgatacga atcctcgtgc
    78541 tggaaaactg cttgattcag atgtgatcgt agaatatgag gaagaacaat ggatcgtgaa
    78601 atctaaaggg gcaaaaaagg caagcaacca ttttgataca aaaaaagaag caatcgaaaa
    78661 aggaaagcaa gtagcacaaa acaaagaatc aactttgttc atttataaaa aagatgggac
    78721 aaaagaaaaa gaaatcgatt attgaacata tgtaaagggg ttgtgacgaa aatcgtgtca
    78781 caaccccctt atgttcgaaa caatggtgtt cctctgccaa ctccgaacca taagtcataa
    78841 tatctataaa acgggaagag ctgttttttg aaattgtttc ttatcactca gtgttaaacg
    78901 gtaggagaaa acctcttttt tattgatatt tgattttcat caaacagtca catagtcgat
    78961 tgcttctgct tgcggaatcg tttcatctac aaagtagact ttataccatg tcaagaaact
    79021 gaagattgtc cagatttttc tttgctcttc tttacgtcct tcgtgatggt catctagcaa
    79081 cttcatgatt ttttcttgat caaaaaattc ttttgcaaaa tctgcttcga ataatgcttt
    79141 gacttgttcg tagccgtgtt cttctttcaa ccaagctttg attggcacag ggaatcctaa
    79201 tttcacacga ttcgaccatt cttccggaag atgtttgttc gcagcttgtc tgaaaatatc
    79261 ttttgtgttg ttttgattca ataaaaactt acttggtatt tgttgagcca atttcatgac
    79321 ttcgatatcc aataaaggta ctcggacttc caaagaactt gccatagaaa gtttatctgc
    79381 ctttaacaag atatcttttg gcatccattg atgaagatcg acatattgca tcttattgac
    79441 ttcatctttg attccttctg ttttctcgta atgaacagtc atgatttcat ccacagatgg
    79501 tgctgtttga tattttggtg ttaacacttc tgatgcttct gattcttcga acactcgagc
    79561 atgaccgata aaatattctt ttgcaggagc aagtgattca tataaatgga tccgtccatg
    79621 gaagtttttc atttttccga ttttacgtcc taaattatag cgtgttcctt ttggtaattt
    79681 tttcaatcct tgagcaatca cacggatgaa ttttgaattc gtatggaatc catacgtttg
    79741 gtatcccgca aacagttcat ccgccccttc tccagattgg actacccgca cactttgtga
    79801 agcaagattt gctaaaaagt acaaaggtac gcaagaagga tttgaatcag gttcatctaa
    79861 gtgatactgg atcaaaggga atgctttgaa cgacatgtct ccgtcgatca ctgctgctgt
    79921 attatctaag tccaatagtt cggttagttt tctggcttca atcgcttcat tataggtttt
    79981 atcatcaaac ccgattgaga aagaatgatc tggtttcaat acagaggtta cataactgga
    80041 atcaaccccg ctggataaga aagaaccaac ttctacatca ctgaccgtat gtgcttcaat
    80101 agaagcttga acggtttcgt cgattttttc gatccattct tgtcgggaat gcgtttcttt
    80161 tgtttcaaaa tctgcatccc aatattgctg aatgtctatt tttccatctt tatacgtata
    80221 ataatggcct tcaggcaaac gatagacatc tttgaagaat gtttcgccgt ttaatggaga
    80281 atattggaaa gtcatataag gtttcaacgc ttctttgttc aattctttgt taaaatcagg
    80341 atgaggcaga aaacttttga tttctgaacc aaacataaat gttccgttca tttctgcata
    80401 ataatatggt ttgatcccaa agtggtctct tgcaccgaat aactcattct tttcattatc
    80461 ccaaatagca aaagcaaaca ttccgcggat cttttgcaat aattctgttc cccattcttc
    80521 gtaaccatgc aaaaggactt ctgtatctgc atgtgtttga aaaacgtggc cagctgcaat
    80581 caattcttct ctcaaaggct ggtaattata gatttcgcca ttaaaaataa tgatctttgt
    80641 ccgatcttca ttgtaaatag gctgagtacc gccctctaag tcaataatac ttaatcttct
    80701 gaatcctaaa gcaacatgtt tatcgatata ttctcctgaa ctattaggtc cacggtgaac
    80761 gattcgatcc atcattgtat taataattgt ttttttgttg tccttgtcgt taacaaaacc
    80821 tacaataccg cacatttaac tttcacatcc taatataaaa ttactgttta tttcattcat
    80881 atgcatctta tcatagaata aatagcggac gaatattttc tctcttacaa tttcgtcacg
    80941 tgaaaacaaa agatgaaagt ttctgttttt acagaaaata aagtcccaat atctaattta
    81001 ccatgttttc ttttttgagg ctaccttatt ctcttcgtgt taaaaaaata ttagtggatg
    81061 ctatttccaa aaaaaccagc aaaaaaagac acgacctaaa
//
LOCUS       DADQDV010000005        65794 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.005, whole genome shotgun sequence.
ACCESSION   DADQDV010000005 DADQDV010000000
VERSION     DADQDV010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 65794)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65794)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65794
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.005"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            476..1339
                     /locus_tag="J8S10_000322"
     CDS             476..1339
                     /locus_tag="J8S10_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAZ9628937.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(1468..3090)
                     /locus_tag="J8S10_000323"
     CDS             complement(1468..3090)
                     /locus_tag="J8S10_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAZ9628938.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            3339..3860
                     /locus_tag="J8S10_000324"
     CDS             3339..3860
                     /locus_tag="J8S10_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9628939.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="J8S10_000325"
     CDS             complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="J8S10_000325"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HAZ9628940.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            5941..6759
                     /locus_tag="J8S10_000326"
     CDS             5941..6759
                     /locus_tag="J8S10_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005232914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HAZ9628941.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKHHFAVFGVMSGFIIMMILDVALG"
     gene            complement(6862..7059)
                     /locus_tag="J8S10_000327"
     CDS             complement(6862..7059)
                     /locus_tag="J8S10_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9628942.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            7228..7806
                     /locus_tag="J8S10_000328"
     CDS             7228..7806
                     /locus_tag="J8S10_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HAZ9628943.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            complement(8851..9354)
                     /locus_tag="J8S10_000329"
     CDS             complement(8851..9354)
                     /locus_tag="J8S10_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HAZ9628944.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            9713..10738
                     /locus_tag="J8S10_000330"
     CDS             9713..10738
                     /locus_tag="J8S10_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAZ9628945.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            11061..11939
                     /locus_tag="J8S10_000331"
     CDS             11061..11939
                     /locus_tag="J8S10_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9628946.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            12415..12531
                     /locus_tag="J8S10_000332"
     CDS             12415..12531
                     /locus_tag="J8S10_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HAZ9628947.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            13459..13797
                     /locus_tag="J8S10_000333"
     CDS             13459..13797
                     /locus_tag="J8S10_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9628948.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            13891..14121
                     /locus_tag="J8S10_000334"
     CDS             13891..14121
                     /locus_tag="J8S10_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9628949.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            14521..14892
                     /locus_tag="J8S10_000335"
     CDS             14521..14892
                     /locus_tag="J8S10_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HAZ9628950.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(15166..15858)
                     /locus_tag="J8S10_000336"
     CDS             complement(15166..15858)
                     /locus_tag="J8S10_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAZ9628951.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(15861..16646)
                     /locus_tag="J8S10_000337"
     CDS             complement(15861..16646)
                     /locus_tag="J8S10_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAZ9628952.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            16883..18283
                     /gene="lacG"
                     /locus_tag="J8S10_000338"
     CDS             16883..18283
                     /gene="lacG"
                     /locus_tag="J8S10_000338"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HAZ9628953.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            18308..18625
                     /locus_tag="J8S10_000339"
     CDS             18308..18625
                     /locus_tag="J8S10_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAZ9628954.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            18638..20311
                     /locus_tag="J8S10_000340"
     CDS             18638..20311
                     /locus_tag="J8S10_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAZ9628955.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            20325..21956
                     /locus_tag="J8S10_000341"
     CDS             20325..21956
                     /locus_tag="J8S10_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016608433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinogalactan endo-1,4-beta-galactosidase"
                     /protein_id="HAZ9628956.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            complement(22447..24012)
                     /gene="guaA"
                     /locus_tag="J8S10_000342"
     CDS             complement(22447..24012)
                     /gene="guaA"
                     /locus_tag="J8S10_000342"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HAZ9628957.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVNARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(24071..24994)
                     /locus_tag="J8S10_000343"
     CDS             complement(24071..24994)
                     /locus_tag="J8S10_000343"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HAZ9628958.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            25190..25795
                     /locus_tag="J8S10_000344"
     CDS             25190..25795
                     /locus_tag="J8S10_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAZ9628959.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            26103..27119
                     /locus_tag="J8S10_000345"
     CDS             26103..27119
                     /locus_tag="J8S10_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAZ9628960.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            27260..28561
                     /locus_tag="J8S10_000346"
     CDS             27260..28561
                     /locus_tag="J8S10_000346"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HAZ9628961.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            28607..29269
                     /gene="deoC"
                     /locus_tag="J8S10_000347"
     CDS             28607..29269
                     /gene="deoC"
                     /locus_tag="J8S10_000347"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HAZ9628962.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            29290..29688
                     /locus_tag="J8S10_000348"
     CDS             29290..29688
                     /locus_tag="J8S10_000348"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HAZ9628963.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            29754..30836
                     /locus_tag="J8S10_000349"
     CDS             29754..30836
                     /locus_tag="J8S10_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HAZ9628964.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            31048..32610
                     /locus_tag="J8S10_000350"
     CDS             31048..32610
                     /locus_tag="J8S10_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9628965.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            32603..33736
                     /locus_tag="J8S10_000351"
     CDS             32603..33736
                     /locus_tag="J8S10_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9628966.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            33736..34692
                     /locus_tag="J8S10_000352"
     CDS             33736..34692
                     /locus_tag="J8S10_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9628967.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            34791..35957
                     /gene="deoB"
                     /locus_tag="J8S10_000353"
     CDS             34791..35957
                     /gene="deoB"
                     /locus_tag="J8S10_000353"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HAZ9628968.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            35981..36799
                     /locus_tag="J8S10_000354"
     CDS             35981..36799
                     /locus_tag="J8S10_000354"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HAZ9628969.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            36816..37523
                     /gene="deoD"
                     /locus_tag="J8S10_000355"
     CDS             36816..37523
                     /gene="deoD"
                     /locus_tag="J8S10_000355"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HAZ9628970.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(37821..38507)
                     /gene="gpmA"
                     /locus_tag="J8S10_000356"
     CDS             complement(37821..38507)
                     /gene="gpmA"
                     /locus_tag="J8S10_000356"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HAZ9628971.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(38679..39260)
                     /locus_tag="J8S10_000357"
     CDS             complement(38679..39260)
                     /locus_tag="J8S10_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAZ9628972.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(39393..40076)
                     /gene="rpiA"
                     /locus_tag="J8S10_000358"
     CDS             complement(39393..40076)
                     /gene="rpiA"
                     /locus_tag="J8S10_000358"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HAZ9628973.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            40395..40808
                     /gene="rpsL"
                     /locus_tag="J8S10_000359"
     CDS             40395..40808
                     /gene="rpsL"
                     /locus_tag="J8S10_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007085295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HAZ9628974.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            40892..41362
                     /gene="rpsG"
                     /locus_tag="J8S10_000360"
     CDS             40892..41362
                     /gene="rpsG"
                     /locus_tag="J8S10_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HAZ9628975.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            41456..43543
                     /gene="fusA"
                     /locus_tag="J8S10_000361"
     CDS             41456..43543
                     /gene="fusA"
                     /locus_tag="J8S10_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HAZ9628976.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSSATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELNLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            43715..44902
                     /gene="tuf"
                     /locus_tag="J8S10_000362"
     CDS             43715..44902
                     /gene="tuf"
                     /locus_tag="J8S10_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HAZ9628977.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            45309..45617
                     /gene="rpsJ"
                     /locus_tag="J8S10_000363"
     CDS             45309..45617
                     /gene="rpsJ"
                     /locus_tag="J8S10_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HAZ9628978.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            45648..46277
                     /gene="rplC"
                     /locus_tag="J8S10_000364"
     CDS             45648..46277
                     /gene="rplC"
                     /locus_tag="J8S10_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HAZ9628979.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            46305..46928
                     /gene="rplD"
                     /locus_tag="J8S10_000365"
     CDS             46305..46928
                     /gene="rplD"
                     /locus_tag="J8S10_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HAZ9628980.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            46928..47218
                     /gene="rplW"
                     /locus_tag="J8S10_000366"
     CDS             46928..47218
                     /gene="rplW"
                     /locus_tag="J8S10_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HAZ9628981.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            47257..48090
                     /gene="rplB"
                     /locus_tag="J8S10_000367"
     CDS             47257..48090
                     /gene="rplB"
                     /locus_tag="J8S10_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010747214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HAZ9628982.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            48133..48411
                     /gene="rpsS"
                     /locus_tag="J8S10_000368"
     CDS             48133..48411
                     /gene="rpsS"
                     /locus_tag="J8S10_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HAZ9628983.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            48434..48781
                     /gene="rplV"
                     /locus_tag="J8S10_000369"
     CDS             48434..48781
                     /gene="rplV"
                     /locus_tag="J8S10_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HAZ9628984.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            48795..49451
                     /gene="rpsC"
                     /locus_tag="J8S10_000370"
     CDS             48795..49451
                     /gene="rpsC"
                     /locus_tag="J8S10_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HAZ9628985.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            49454..49888
                     /gene="rplP"
                     /locus_tag="J8S10_000371"
     CDS             49454..49888
                     /gene="rplP"
                     /locus_tag="J8S10_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HAZ9628986.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            49878..50066
                     /gene="rpmC"
                     /locus_tag="J8S10_000372"
     CDS             49878..50066
                     /gene="rpmC"
                     /locus_tag="J8S10_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HAZ9628987.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            50091..50357
                     /gene="rpsQ"
                     /locus_tag="J8S10_000373"
     CDS             50091..50357
                     /gene="rpsQ"
                     /locus_tag="J8S10_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HAZ9628988.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            50415..50783
                     /gene="rplN"
                     /locus_tag="J8S10_000374"
     CDS             50415..50783
                     /gene="rplN"
                     /locus_tag="J8S10_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002460061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HAZ9628989.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            50820..51128
                     /gene="rplX"
                     /locus_tag="J8S10_000375"
     CDS             50820..51128
                     /gene="rplX"
                     /locus_tag="J8S10_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HAZ9628990.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            51156..51695
                     /gene="rplE"
                     /locus_tag="J8S10_000376"
     CDS             51156..51695
                     /gene="rplE"
                     /locus_tag="J8S10_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HAZ9628991.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            51714..51899
                     /locus_tag="J8S10_000377"
     CDS             51714..51899
                     /locus_tag="J8S10_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HAZ9628992.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            51935..52333
                     /gene="rpsH"
                     /locus_tag="J8S10_000378"
     CDS             51935..52333
                     /gene="rpsH"
                     /locus_tag="J8S10_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HAZ9628993.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            52365..52901
                     /gene="rplF"
                     /locus_tag="J8S10_000379"
     CDS             52365..52901
                     /gene="rplF"
                     /locus_tag="J8S10_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HAZ9628994.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            53062..53418
                     /gene="rplR"
                     /locus_tag="J8S10_000380"
     CDS             53062..53418
                     /gene="rplR"
                     /locus_tag="J8S10_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HAZ9628995.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            53439..53939
                     /gene="rpsE"
                     /locus_tag="J8S10_000381"
     CDS             53439..53939
                     /gene="rpsE"
                     /locus_tag="J8S10_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HAZ9628996.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            53954..54133
                     /gene="rpmD"
                     /locus_tag="J8S10_000382"
     CDS             53954..54133
                     /gene="rpmD"
                     /locus_tag="J8S10_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HAZ9628997.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            54177..54617
                     /gene="rplO"
                     /locus_tag="J8S10_000383"
     CDS             54177..54617
                     /gene="rplO"
                     /locus_tag="J8S10_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HAZ9628998.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            54617..55912
                     /gene="secY"
                     /locus_tag="J8S10_000384"
     CDS             54617..55912
                     /gene="secY"
                     /locus_tag="J8S10_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HAZ9628999.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            55974..56621
                     /locus_tag="J8S10_000385"
     CDS             55974..56621
                     /locus_tag="J8S10_000385"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HAZ9629000.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            56812..57030
                     /gene="infA"
                     /locus_tag="J8S10_000386"
     CDS             56812..57030
                     /gene="infA"
                     /locus_tag="J8S10_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HAZ9629001.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            57063..57179
                     /gene="rpmJ"
                     /locus_tag="J8S10_000387"
     CDS             57063..57179
                     /gene="rpmJ"
                     /locus_tag="J8S10_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HAZ9629002.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            57197..57562
                     /gene="rpsM"
                     /locus_tag="J8S10_000388"
     CDS             57197..57562
                     /gene="rpsM"
                     /locus_tag="J8S10_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HAZ9629003.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            57590..57979
                     /gene="rpsK"
                     /locus_tag="J8S10_000389"
     CDS             57590..57979
                     /gene="rpsK"
                     /locus_tag="J8S10_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HAZ9629004.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            58059..58997
                     /locus_tag="J8S10_000390"
     CDS             58059..58997
                     /locus_tag="J8S10_000390"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HAZ9629005.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            59025..59405
                     /gene="rplQ"
                     /locus_tag="J8S10_000391"
     CDS             59025..59405
                     /gene="rplQ"
                     /locus_tag="J8S10_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HAZ9629006.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            59677..60516
                     /locus_tag="J8S10_000392"
     CDS             59677..60516
                     /locus_tag="J8S10_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HAZ9629007.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            60492..61361
                     /locus_tag="J8S10_000393"
     CDS             60492..61361
                     /locus_tag="J8S10_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HAZ9629008.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            61351..62148
                     /locus_tag="J8S10_000394"
     CDS             61351..62148
                     /locus_tag="J8S10_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HAZ9629009.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            62351..63097
                     /gene="truA"
                     /locus_tag="J8S10_000395"
     CDS             62351..63097
                     /gene="truA"
                     /locus_tag="J8S10_000395"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HAZ9629010.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKVRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            63762..63999
                     /locus_tag="J8S10_000396"
                     /pseudo
     CDS             63762..63999
                     /locus_tag="J8S10_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299509.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(64143..64919)
                     /locus_tag="J8S10_000397"
     CDS             complement(64143..64919)
                     /locus_tag="J8S10_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAZ9629011.1"
                     /translation="MNIHHIRNATAILDYGGKKFLIDPMLAEKGTLPPFISKGPFPSP
                     RKDQMNPLVDLPMPVEDIINGIDAVIVTHLHLDHWDDIAKEVLPKEIKLFVQDENDAN
                     EIRLYGFKNVEVLREDTVFESIQLVKTKGKHGRGEILNYVGNVCGIVFKHSTEKTLYF
                     TGDTVWYEAVKQTIDQYNPEIIVANAGDNHFLVGESLIMGKDDLYELHKAIPDSTIIA
                     VHMEAVNHWGLSREELKSFNKEKGISEKVLVPEDGDNIFI"
     gene            65042..65449
                     /locus_tag="J8S10_000398"
     CDS             65042..65449
                     /locus_tag="J8S10_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HAZ9629012.1"
                     /translation="MLDQTDINIIEELSKNSRITMKELGEKVHLTGPAVSARVTKLEE
                     SGVIENYTVKLNMEKLGFSIHAFLIIITQNLNHKPYLSFIKNHEKFLIRNYKISGGGC
                     YLLECRFTSKKSMNSFLEQLNEYANYKLSIVID"
BASE COUNT        20925 a        11725 c        13856 g        19288 t
ORIGIN      
        1 ccactaaacg gtgttctcct gccaactcct cggtcacaag tcacaatatt caacaaacat
       61 gagaagctgt tttttgaaat tgttccttgt gactcggagc taaacggcag gctcacaacc
      121 tcttggtaaa cggtgttcaa tcagctgacc ctcggtatta gctcaaaaaa cggcaaaata
      181 tgaggaacta ttttttccgt ttttttctct aatactcagg tcaaaacgct gatttcacaa
      241 cctctgattc acggtgttcc agaagtagct tctacggaaa taagccgaaa tttcacaaaa
      301 atttgagaag caattttcgt aaattccttc ttatttcttg aagctgacca cttctgtcac
      361 aacctcttat tttgattaga acttgcgaaa ataaaccggt taaagtgtgt ctagcgcaag
      421 agatttgcta taatagacga taagggtaaa atgtaacgag aaggggttga aaaatgtgta
      481 tcaaattgta acagattctt gttgtgatct gccataccat gtattagcaa aagaaaaagt
      541 tgatttttta tcaatgaatc tccaattgaa tgatcaagag ttagtagatg acctcggaaa
      601 gacattcaat tatgaccgct acatgaatca gctgaaaaat ggtgcgatgc ctacgacatc
      661 acaaatcaat gttggccgat atttagaatt tttccgttct tatgcggaaa aacagattcc
      721 tgttttatat gtggcttttt ccagtggatt aagcggctct tacagtagtg cgcttcaagc
      781 ggttgaattg ctgaaggaag aatatgaaga ccctgagatc tatgtttttg atacaaaagc
      841 tgcaagtatt ggggaagggc ttttagtatt ggaagctgta agattgaaaa aagaaggtaa
      901 aagcatcgaa gaaaccctag agtggctgga aagtaattat ttgaaagtcc attcatgggt
      961 aacagtagac gatctgaaat atctagaacg aggcggtagg atttccaaag caagtgctac
     1021 tcttggcagt ctattgagtg taaagcctat tattacggtg gataaagaag gaaggctgac
     1081 gaatgttgac aaagttcgag gaagaaacaa gtcgatccag acaatcgtca atgagacggt
     1141 aaaaacaatc gttgcaccac ttgatcaaat cgtttatgtg gcttacgctg gggatctaga
     1201 gagcgcggag aaggcaaaac ggcttttgga agagcagata aagatgaaag atgtgaagct
     1261 ttatccctta ggaccaacga tcgccagtca cacaggctat ggctgtatcg cgattttttc
     1321 gatgggaatc agtcgataaa agcagtaact cattctgtaa aaaagcccag aaattgattg
     1381 taacaaaaac agcgactctt aaaagataga tgagcatcct atctcttaga ggtcgctgtt
     1441 tttttatttt ttaagctaaa taggccatta tgcccataac tcgttcaatt gtttttgaat
     1501 atctgcattt tccaaaaatt catcatatgt cgtatcagct cgatcgatca cacctttatc
     1561 cgaaacggca atgatgcggt ttgccaatgt ttggataaat tgatggtcat gtgacgcaaa
     1621 taagattgag ccagtaaatg ccatcaagcc gtcattcaat gctgtgattg attctaagtc
     1681 taaatggttc gttggatcat ctaatacaag tacgttagct ttcgaaagca tcatttttga
     1741 aagcatgcaa cggactttct ctccaccaga taaaacattc actggtttca atacttcttc
     1801 accagaaaac aacattcttc ctaagaagct tcttaagaag gtgttatcat cttcttcttt
     1861 acttgcatat tgacgcaacc agtctaaaat cgttagatca gtatcgaatt ctttcgttgt
     1921 atcctttggt aaataagaat tacttgttgt cacaccccaa cgtactgttc cagtatctgg
     1981 cgtaatttca cccatgataa ctttgaatag cgttgttgtt gttatatcat tttctgcgac
     2041 gaaagcgacc ttgtcttctt tgctcaaatt aaaagatata tcatctaaaa ttttctttcc
     2101 atcaatcgtt acacttacat tttctacctg caataagtcg tttccaatct cacgttcagg
     2161 tttgaatcca acgaatggat aacgtctaga agaaggttgg atatcgtcta aagtaatttt
     2221 ttcaagcatt tttttacgtg aagttgcttg ttttgatttt gatgcattcg cactaaagcg
     2281 ggcaataaat tcttggagtt ctttgatttg ttcttctttt ttggcatttg cgtttgcttg
     2341 aagtttagcc gctagttgac tagattccaa ccaaaaatca taatttccta cataaagttt
     2401 gattttacca aaatctagat ccgccatatg tgtacatact ttgttcaaaa agtgacggtc
     2461 atgggataca acgatcacag tattttcaaa attgatcaaa aattcttcca gccaattgat
     2521 cgattggata tccagaccgt ttgttggttc gtctagcaaa agaacatcag gtttaccaaa
     2581 tagtgtttgt gctaataaca cttttacctt ttgtccacca gttaattcac tcatttgctg
     2641 atggtgcaat tcttcaggga tgttcagacc ttgcagtaaa acagctgctt ctggttcagc
     2701 ttcccatcca ttaagctcag caaattctcc ttctaattca gctgctcgaa taccatcttc
     2761 gtcagtgaaa tcctctttca tgtaaatcgc atctttttct ttcagcactt catacagacg
     2821 cttgtgtccc atgatgactg tttcaagtac agtatagtct tcatagtcgt aatggttctg
     2881 tttcaatacg gccatccgtt catctggtcc catagtaacg gaacctgtgg aaggctgcag
     2941 atcccctgat aacactttaa ggaacgttga tttacctgca ccatttgcac caatcaagcc
     3001 atagcagttt ccgggggtaa atttaatatt cacatcatca aatagtttgc ggtctgaaaa
     3061 gtgcaaactc acatcattta cagtaatcaa tttttttcct cacttttatc attattagtt
     3121 ttgacaagtc ttatagaatt atatagggga aaggtaaaag attcaaggca atcgaacatt
     3181 ctttgtgttt cacgtgaaac agaatgaaaa aaataaaaat aaaagcggag cgaaaatagc
     3241 tactatagga tttattagtt tgcaacagca taatttttga cgttatttat aagagggagt
     3301 actataaaac tgtaaaagaa atgaaagaag gattgaaaat ggatgaaaaa agaaccatcg
     3361 actggggctc attgattttg ggaattttat ttgtacttgt ctcattgtta tcatttcaag
     3421 accctgtcgg aaatttagtt gcaattgtag tagtctttgc gatttttgcc tttattaaag
     3481 ggatatttga actgtttgta cggaacagat taaaagagct aacaggatat aaaggaaaga
     3541 tgcccttaat aatcgggatc atcgatattc tagttggcgt ctttttctta ttcaatattg
     3601 gtgcaggagt cgcagcattg ccttttgttt ttgcagtatg gtttattgct gattcagttt
     3661 tagcgttatt tactgctgac ttggcaagag gagtaagtga aggatattat tggtttacga
     3721 tcatcgtcaa tattttagga attttattag gaattttctt attgtttaat ccaatttctt
     3781 ctgcgttgac attaagcttt ttagttggat tctattttat gttatttggt atcacacata
     3841 tcgtctatgc atttagataa gtaaaatcaa acaaataaaa aagccggctt ccgattacag
     3901 ttttactgtt gtaattggaa gccggctttt ttatcatgga caaatatgca cgaggtgatt
     3961 tttaggtgtc gagacaaatt tatgcaaaaa tgtgagaagc tatatacaca aattttatct
     4021 taatactcga agcatagcgc agttgtcaca acctcttttc atataattca ttcaatactg
     4081 gcaaatcatg gacttcatat ttttctttga atgcttggat ttcttcttca gaatattttc
     4141 ttggatctaa atgcagatct tctactggca atgggcgctt gttattgatc ttcacatcga
     4201 ttactacagg acgatctgat tttgcagctg catcaaaggc aaatcgaagt tgcgagtatt
     4261 ctgtgactgt aaagctattt gccccgagcg cttctccaac tttaccgaaa tctgcatctt
     4321 ctaaaaatac accaaatttc ttttgttccg tatcttcttg ttctgcttcg atgaaaccaa
     4381 aagaatcatt cgaaaagaca acattaataa ttggaagctg atatttgact tgtgtaatga
     4441 tatcttgcat gaccatagca aacccgccat caccacttaa ggtaaatact tgtttttctg
     4501 ggtagcttag ttgtgcggca attcctcctg gcacaccatt acccatagtt gcgaaccatc
     4561 cagatgtcgt atgtttttgt ttaccgttca tattcaataa acgaatagaa tggatagtcg
     4621 tgttaccgac atctgtgacg aaaatcgcat cgtcttcagc aatacgattg atttctttat
     4681 agacagcctc tggacgaatc ggttcttcct ctcgatcttc aaaagatttc aaccaattta
     4741 cccatttttc tttattttct tgatttgcta ggtaccagct atcagcaggg cgagcatccc
     4801 ctaactcgac aagtctttgc aaagctgtgt ttgcatcacc gaggatcgac aaagatgttt
     4861 catggcgtcg tccaaatttt gacgcatcga tatcgatttg gataaattca gcagttggat
     4921 taaaaaatgc acgtccaaat gggaagtcgc taccgacaaa taagatcaga tcggcttctg
     4981 ccaatgcttc atttccgggt ttagtagcga cacgtccagc aaaaccaaga aagttttcat
     5041 aatcatcagg aataattcct tttgctagaa cggaagcgac aacaggaact gaaaaatgtt
     5101 ctgagaattc tttgatttgc ggaaatccgt ttcgcgttcc ttgaccaaca taaagaactg
     5161 gtttttttgc tttttcaaga taaggcaaag cagctagcaa atctttttct tctggtaata
     5221 tcacacttgt tttgtgagtg tgagcggtgg agaaaggttg ttcgtcaatt tcttcaaaac
     5281 caagatcaac agggatagtc acgatagcca cgcctttatg ctcataggcg gctttaatgg
     5341 cttcatctac tacatgcgga agactttgtg gtgtcatgac tgtacgattg tatacgctaa
     5401 catctgcgaa aataggattt tcatttagtt cctggaaaga gttatagttc atggatgtag
     5461 aagcaacttg tcctaagaac gctactagag gcacatggtc catctgtgca tcatacaaac
     5521 cattgatcaa atgtgtcgca ccaggtcctg cagagccgaa gacagcgccg actttccccg
     5581 ttaattttgc atctgcagcg gctgcgagtg cgccgacttc ttcatgacga acttgaatgt
     5641 agttgatttc ggttttttct tgatatagcg catccataat tgaattgaaa gatcctccgg
     5701 gaatgccgta aatatggtcg ataccccagc tttcaagaac ttttaccatt gcgattcctg
     5761 cattgatttt tgacatggtg tttcactcct ttagcaatga tgatacataa attttttgta
     5821 tctagagtat agaacttttt atcgaaaatc ccaactaatt cgtcttttca caaaaatgta
     5881 gtcatgtttt tgggaatatg ctagagtagt acatagatag attcaagaga ggggaatggc
     5941 atggttgaat ggctattgag acttgaacct tggcagcaag cacttgctgg gacagctttt
     6001 acttatttta tgacagctct tggtgccggg ttggtttttt tctttaaaga aatcaaaaaa
     6061 gaagtgctaa acttgatgtt aggatttgct tctggtgtca tgattgctgc aagtttttgg
     6121 tctttgttag atccggctat tacaaaagca gaagaaaatg gagatattgc ttggctagtt
     6181 gtaagtattg ggtttggttt aggcggtgtg tttttatata tggcagataa aacactgccc
     6241 catatgcatt ttggaccaca acatgaagca gaaggattgc ctacccattt aaaacggacg
     6301 atcttgcttg ttttttctat tacattgcat aacattcctg aaggtttagc cgtgggggta
     6361 gcattcggtg cagcagcaac tgcggataat ccgacagccg ctatattagc cgctgtttcg
     6421 gtggcgctag gtattggtat ccaaaacttc ccagaaggag cagctgtatc aatcccgttg
     6481 cgacaagaag gtctgagtcg taaaaaggcc tttgtttacg gacaagcttc tggaatcgtt
     6541 gaaccaattg ctggagtgat tggagcgcta ctagtaacga aagtggagct gctgcttcct
     6601 tatgcacttg cttttgccgc aggagcaatg atttatgtcg tggtggaaga attgatccct
     6661 gaagcacagc agacattgtc cagcaaacat cattttgcag tttttggcgt catgagtgga
     6721 tttatcatta tgatgatttt ggatgtggca ttaggataaa taaaaaaaat atatatgata
     6781 tatcaaatag ggccgcgaac ttatatcgcg accctatttt tttagtaagt tatatcataa
     6841 tgaagtgaat ggtatcatac attaataata gttttttcta tgtgtatttc ctttgatcca
     6901 gcgaacaagc cagatgataa gtgcgattgg gattagaact ttgaccgcaa accataaaag
     6961 cccgcttagg acactgacaa aaagactgat gacgaagcta gctgcaatta gcactaaaag
     7021 aaccatgaag atatttaaga acatattttt ttgacgcata caaaaccctc ctcttgttca
     7081 ttctttacta tagaaaaagt ataacaggga ttgtttaaaa acacctccaa ctgaagactg
     7141 atttttactt catctactta aatgatcaaa caattgcttt ttctctggtt tatcatctaa
     7201 aatagagcgg aaaaggagga gaatatcatg cctaaaaatc gtcttgaagc atttacagat
     7261 gctgtaatcg cgattatcat gactatttta gttttagaac ttcatgaacc taacggagac
     7321 acgtgggagg cgctcgctgc attaggttac cgatttttta tctatattgt cagttttatc
     7381 attttagcga tttattggaa caatcatcat catttatttc aagttgtaca taagataaat
     7441 ggacgggtct tatgggcgaa cagtttcttt gtttttgcgc tttcgctttt tccgtttgca
     7501 acttcatgga tcagtgagta catcaatagc ctggctccag aaatgactta tggttttgtt
     7561 accttgaccg ctaatattgc gtattatatc ttggcaaaag aacttgtcaa agcaaataaa
     7621 ggccacgaga aagcattgaa ggcgatgttg aataattaca agaaatcgta tctatcgatt
     7681 ggtttgaatg tgttaggaat tgtcttaggg tatttagtag cgccagtagc cgtgctgatc
     7741 gcaaacatcg tgattctagc tgcttggatc atcccaagtc gtaccatcga atcacaatat
     7801 cggtaaaatg atccgtgttt aaaatttaag agaaaaatat agaaaaaata aataaacgat
     7861 caaatatccg agtgatacta gtattcaaag agggatgcag atggatcaaa aaagaattca
     7921 tgtaggactg attactagtt ttgtcacgat gcttatttat ttggatcaag gtcatttgac
     7981 ttggacagta gttggtgtcg taggattttt gacattattc acagcaataa aaaaataaac
     8041 atctttatgt aatctgatgt tctatctatt taagaaaagc atgtttacag cagtatgatt
     8101 ctgttgtaaa cgtgttttta tttgtggaaa atttaatttt tagaaaagtg tatcgaaaaa
     8161 tagatagtta gtttttccac agtggataac ttcgtaagag ataaaaataa aaaattagtc
     8221 aaagaagggc gtatagattt cttttgatag gagatataca acagaaatga ataaatatta
     8281 acgtgttttc aaacagtata aaacggtgtg gtttttggaa taaaaaaata acatatctca
     8341 ttttacactt ttgttatttt atacttaaaa aataacgaca cagaaaatac cgtgtctcag
     8401 atttctctac tacttctaaa aactactgtt tttttccttt gaaatgcctt caaaaagtag
     8461 gatcaggcag aatatactgg cagaatcaag gagaagggag cctaaataag gagaaaaacc
     8521 atagaaaata taaagtaatt acttataaaa caagcttttt atagaaaaat aatatacctg
     8581 agtagggtat aaattaagac ggaattcctt tctagattga gatattgact aggaagaatg
     8641 ttaagatttt aagcctttaa gctaaaaaaa aacccttttt gttaaataag gggaatatag
     8701 cctgtcagtt tcaaactgca agtcgtcctg ctgcaataat atagtagatt agagatgaaa
     8761 atagattttt ttaaaccaat gactgaataa aaagaccgtc atagatacac attggaatgt
     8821 gtctattacg gtcttttttt acgaacgatt ttattgaaga cggacagttc gggtcaaaaa
     8881 taaaaaagct acgatcagaa ataagaataa aatgtatccc aaaataatgg ctagacggtc
     8941 taacttattt gtcgatagat gtttgtttag aagttgatag gcccataaac ctatcagtcc
     9001 tcctgttgta ttagttatca aatcagtgat gtccgctacg ccaataccga ataggaattg
     9061 aatcaattct gccaagaagc ttacaaggaa aataatccct aattttttag aaaaagaaag
     9121 tctcttgaaa ttgacattca aaagcacccc aaaaggaaaa aagacaatca agttataagt
     9181 ggtctcacgt aataccgtcg tattttcaaa agaaaaagta gaaaaaggga cgagattgac
     9241 attgctgtaa gaataagtga gaaattgtgg aagattaaat gatagcttga ataaaatcaa
     9301 ccataataga aagaataaat aaatccctaa taaaaatttt gatacatacc gcatagacat
     9361 ctcctccatt taaaaagtat accatcgaaa accgctgaaa aatcataaaa aagtatgaag
     9421 tttaaggacc aacgtagtta tcgtacgaaa attagaagct tttttttgtt gggaatccgg
     9481 tttctttaac aaagctaaga tagcgagttg cttggaaaag ttgctatctt ttttctgtca
     9541 aaacgactcg gaatgttcgt tttttgttct aatttctcca agttgtttac tttttgatac
     9601 taagtttatg aaaaatcaag aaatagttgt tatactaggt aatgctgaca aacgggattg
     9661 gcatttcatc ttggttcagc tttttttcca attactagga aggagggata gattgttcaa
     9721 gacttatttt cgtttcaata aaatacaaga taatcctttt cgtatcatga atctgatgct
     9781 acttatcttt attgtattat ggttaggtta cataaatcat gattttttga tttcaagttt
     9841 ttcatcatta gggatcttta cttttttcta ttatcaaaac ataccgatga aatatttgct
     9901 gaaacgtatg tttctgatcg gttgcggact gttggttgct ttcgttttgg ggatcttatc
     9961 gacttatgtt ttatggcttg aaccatttgc cgtagctttg gttgcttttt ccagcagatt
    10021 cgtgttgcga ttattccata tttctaaacc aggtggcttg ttttttgcga tgctttctgc
    10081 catgggaacg agcatgcagc tgccaatcgc tcaattaccg atcgtctcac tttatttttt
    10141 tatgggtgtc gtttttgccc tgattgcggc agtgattaca aaattactgg attcacggcc
    10201 tgagcagaca attgaaaaag caactttaaa agaaagattt cacgaagagc ctttagtgat
    10261 cattgattct gttttctaca gcgctgcctt atttctttcc gtttatgtca gtcacggctt
    10321 gaatctgcat aatccttatt ggttgacctt gtcatgtgca tcgattttgc tagcagaaaa
    10381 cttggatgcg atgaagcatc gacaagtcca atatctgatt ggatcgatgg gtgggttatg
    10441 tgtgtcggca ttcttgtcat ttgtgccgtt tacgcagttg cagaccattt ttctgatcac
    10501 ttttctatat ggaatcgcac aatttctagt tgctagaaat tatgcagttg ctaatatttt
    10561 tcttaatccg atggcgttga tgctatctac acttattcgt ggagcatact tgatttcttt
    10621 gatcgaatat cgttttttag ggatcgtcat aggaagtttc atcggtttag gtgttgcgtg
    10681 ggtaatgacg gttggtttgc aacattattt aacggttgtt cgtcaaaaat tagaatagaa
    10741 ggacaaatat atgtgccaaa agaggttatg acaagatttt tgtcacaacc tctaattcaa
    10801 ggtgttcaaa agccagattc tcagcattaa gtcaaattca cacaaaaatg tggaaaggaa
    10861 ctttcaaaaa aattttatat ttattctatc aaaaaatttt gtttatgatg gtaactgaat
    10921 aaactttcct gagatggtca atgctttcct tgaaagtctt acagatattc tttcttcata
    10981 gaaagtttaa gttttatagt tagtgtacaa taaaagtatg tttataccat atggtgtccg
    11041 gataatcagt catttaaaca atgaggttca aagatatgaa aaggggaaat ttgatgaaga
    11101 aaataagcaa tgaaatccaa attctggcag aaactttaac tcttcccaaa gtcgttatag
    11161 agcaaatgat tgtacaagca aaaaacatcc ttgatgaggt gtttgagcaa tatagtcatg
    11221 aactaatgga tcctaataaa gcaaaggcga ctgcaaagaa aatagacaaa gtctatgaag
    11281 aggaaccttt tgcagcatta gctatttatc tatatgcagc ttctcaaagt tggaaaaaaa
    11341 tttatcaacc attgaagatt ccaagaacta tctatttggc aacaatgaat gcttttacta
    11401 gatttattca tgaacatttc caagtaacag gaagctatcg ctttgaccgt ggtttttgga
    11461 tttggcatta cactagtggc ttgatctttc ggattggtga attggagtac gaaatgacat
    11521 attttccgaa agggtacacg gatctaagat tagaaggaaa gcagtgcctt tctcttcata
    11581 ttccttccga tgcagattta tctcagaata agataagaga tagttacgaa agtgccattc
    11641 gtttttttga actttatttt cctgattacc attaccaagt gatgtacaca gatacttggt
    11701 tactatcacc caatcttact aaatggttga aaaaagagtc aaaaatctgt ctttttgcag
    11761 ccgattatcg attattatca gttgatgaac aggacgatag tggagtccct tggatctttg
    11821 gacgagtaga tgcccaaata catgattatc cagaaagtac gagtttacag cgacaagcaa
    11881 aagagcaatt gcttgcaggc gagcacattg gctctggctt aggtattctt acttcataag
    11941 tttagtactt cgaaatagtt taaaagagcg tgagacaaaa gtaaagaaca cttttgtctc
    12001 acgctctaaa cacgtataaa cggcggaagc agaagcaact ccttcggaaa taagctgaaa
    12061 ttcacaaaaa tttgaaaagc aattttcgtg aatttcttct tatttcttgg agttaaacgc
    12121 ttctgtccca gcctcttttt tagtgttcta tcgaacacac agtacgttca ataggtaaac
    12181 tagctataac aatagatatt aaagttaacg gacaagaggg ccttttttag gtagctaaaa
    12241 cgtaataatg aaaatttatt tccagagata ggagtcaatc agctagtctg atcgactgtt
    12301 ttaacaagtt gactttcatt ttaacttttg ataccattta aaacacaaat cgtaattgtt
    12361 tcgatttgtg ttttttagca tgactacaat caaagaagaa agtgggtcgt ccatatggaa
    12421 aaaacagata tctcaagtgc ataccgccgc ttgaaaagcc caaatatcaa aacacgaaaa
    12481 cgtgcgctga agatcatcaa agatgtgaaa cggaatagtg ggaaaaggta agaagaagga
    12541 aacttaatta aaaaaatagc cgaaaaacgt ttttcggcta ttttcaataa tcggtttttg
    12601 tgtaaggttt ccgaaagaac tgctgttgat tttccatttt taacatatga taaattggta
    12661 gaatctttct tttcaaattg ataccattcc ctaattccag ttatatagtt aactacagaa
    12721 ccacaaagca cgtacgttta taaaagtatt atctgtagtt atttttcaat tccctttcaa
    12781 cctcttattt tgaccagtag tattgatcac tttacctttt aacacctttg ttcgtttttg
    12841 aaacattttt agtcaagaat ggaaacgtaa ctacataatc aaaggttttg cgaaatattt
    12901 catgaaatat ttcatgtaga agcgagcaat acggttgcaa ataaccatta tcgtttaata
    12961 agcagttacg aaagctccca atatctctaa cgttcagctc actccatttc ttttcttcaa
    13021 aaaaatcagt gattcgtatc tctttctatt tgtcgaaaaa gttaacttta aaaagtaacg
    13081 ccgaaaaaat atgcaaaaaa ataaaaaagc agttactatt gctagaataa catcaaggaa
    13141 taataagttt tggttttcag ataatagtcg ataagttgtg tattggaatt ttagatacag
    13201 taataaagta tttttcatga aattttgtga gaatcactat tacaagtatc tttaataaaa
    13261 ttaatggtta aggaggaact taaagtagaa tgtaaatgaa tagttgtagt cagtcgattg
    13321 tgatactaga ctcaaagttg caggaataag tttttcaatt tgtgattgga agataaaaaa
    13381 tgaaaaagaa gggctttttt ttatactttg ttgattgtag tgtttatttt ccctctgttt
    13441 agccaagtaa cattttctat gactcaacca gtttcaagtg aggaacatga taaccttttt
    13501 cgtgctacag aagagtttaa gaaatatcag gaaaatattg ttccggagac tccattagct
    13561 agtgagccaa ttactgatat tgatggaaac caaataggat ggtatataca gtacgaagtt
    13621 atggtggtaa ataatgactc aatagtaaaa aatacagtag gcttagagct aacaccgatt
    13681 gaaaaggtga gttcattgtt aacgtatatt tatactgatg aaagtgacga gactgagatc
    13741 attttaacgg attactcaaa aattgctact gataaaaagt atatattgtg gatgtagaca
    13801 ctagtgaaat actttatgat atagaaattg atgaaaattt actagatgta gcacaagaaa
    13861 tcgatcatca aaagcaggaa gctattcgat atgctggtag aaaagggaaa agaaaatatt
    13921 tattacgtga atgtagcaaa agttagagaa gatgaaaatg agtggaaaga attcaagagt
    13981 cgctactcaa ttaactcgac tccgacattt acagtttaca gagaaggatc gatagaaaaa
    14041 actgtttttt ggactaaaga aagtggaatg tctttagctg aagtagaaga gtttttggat
    14101 tatgttagta tgcaacagta agggagttct tattatgaaa aattttgaca catattatgt
    14161 tattgttttt tcgatatctt tgctgttaat attactaact ttaatgcagt ataaagagta
    14221 tccagagtat tttattttaa cttttgtata tttagtaagt agctacacac ttctatataa
    14281 attcagaagt tcttctagag tttctaaagt ttgtttctta attagcttat tgattctata
    14341 atatttttga tttatatagg aaattaaaaa tattatagaa tcaacactca gagaacgggt
    14401 tggtttttaa tagatttaat aagtactgat aatgaaattt ctcctggttg ggaaaacgaa
    14461 gttggttacc ctgtagaaga attttttcaa gattactttg cggagtatgc cgataggata
    14521 atgagagatt acgtaacaga taaaactcaa gaagtcatca atcaatccca gtcattaaat
    14581 gaattatctg ataaggcgaa agaagaagca gttgccatta tttcttcagg gattagtgac
    14641 tatattgata tgagtggtga aatcaattat ggcgataaag acaaaattgt acgcatgata
    14701 aaagctttta tcaaaacttt tgatgtgaag gcagatctta agtttaatga tacttaccta
    14761 gtaggaaaat taattaatat ccttgggaca gagaaagata cggaaacgtt tatttcctct
    14821 ttgtctatgt tgtttacaga taagcatttt tcaactcagc ttggtggaga ggaactagtg
    14881 gaaatctttt aaccattacg cccagcatta ataaaagtat atcaaaaaag tactcctgat
    14941 gatttttaag attggtttga gaaataatgt gaaaacacta tttttaatgt taattataga
    15001 tagagatgaa cgcgtcatat ggttaaaaga atgaaaaagt caaagataca ctgctatatt
    15061 tcactaagga tatagcagtg tatctttcat gtcgtttcac tggcagtttt ttataaaagg
    15121 aggtgtgcat ttcagttgct tttctttggt agttagttga atcgtttaag aattaacgga
    15181 tgtggcagac aggtgctctg tccaaaaacc agtaaaatct ttgatggttc catctttatt
    15241 tagctgtgcc tgttcaaata ctgttttgtt tttaccgaat ggatcaattg caataattgt
    15301 tccgatcccc gcacgtttgg cagcaagtaa tcctgagtaa gcatcttcga taacaagaca
    15361 atcagccgga gctaagctca gtttgtctgc cgctttaaga aaaatatccg gttgcggttt
    15421 cccagggaaa gagccgtcgt catagacaat cttgtcccag tcaaaccagc gggctaaatc
    15481 gaaaatatca aaataaaaag caacattctc tttgacagta gccgtggcaa tcgttaatgg
    15541 aatctgttgg tcagtcagct ggtcaagagt cgcttcaagc ccttttgtca actgaagctc
    15601 gttttcattt tgcaagcaaa gcatacgata atagctttct ttttcttctg acaatacggc
    15661 gatctcagag gcggtcaaat gctctgaaat gaaatgtttc aaaatctccg tattcgtccg
    15721 accatgaata ttttttaaaa tatcctcgtc tgataaacca tcttttgtat gatcatgtat
    15781 catatgcagc caagcagctt catgcagatg agagtccaaa aacattgttc cgttgaaatc
    15841 aaatataatc cctttcatag ttacgctcct atagtggtat tttcggttga atcagcaatt
    15901 tgcagatcga catattgtgc atagtgctct tgaacctccc gcgagatctg gcgatccgta
    15961 atgagcagat cgaaatcatg caaattataa aacacataaa aatcatctcg attgaatttt
    16021 ttattatcaa cgagtagata tttcttacgg gaattattta gagcgatctg ctgtgcttct
    16081 ccttcttcgg tactgtaagt agagatcgct tcgttgtgaa cgccatttga actgataaat
    16141 gcttttgtaa actttagtct tcttaaattg tcgttggtga tcggtccgac aaatgcgccg
    16201 gtatttttcc ggaaatcacc gccaatcagt agaatttctg gtccatctgc ttgagcaaga
    16261 atatcaaaaa ctggataatt atttgtaatg atccgaattt tcttgttcag taaatgcgtc
    16321 gccaatagtt cgattgttgt acctggtcct aagaaaatcg tttctccctc gtgaatcaag
    16381 gaggctgctg tggcagcaat ttcttttttt tcttgaatct gcagagtggc tttttcagtg
    16441 tgagaaagtt cttgatctaa agtgtaggaa agactttgag cccctccatg gacacgcagc
    16501 agcttgcccg atttttctaa ttcatctaaa tctctgcgaa cggtcatatc agaaacatct
    16561 aattgattga tgatttcatt aacggtaagg attccttttt tattgaccat ttctacgata
    16621 gtaagcaatc tttctttttt caacattgtc ttcacctcta atttaaggat aatctatcat
    16681 ataaacggac aacagtcaat ctaattcgaa caaaagtaaa catttagggt ggtttttatg
    16741 tttgttacaa tagattttat tgctgttttc tggtttttat gattatttgt gtttgttttt
    16801 gttgacaaat gttttggatg cgtttacaat gcaatcagtt agaaagagcg aaaactgatt
    16861 atagatttga ggagagatgt acatgcttaa attaccagaa gattttattt ttggcggagc
    16921 cacagcagcc tatcaggttg aaggagccac taaggaaggt ggcaaaggcg ctgttgcttg
    16981 ggatgacttt ttagaggaac aagggcgatt cagtcccgat ccggcaagtg atttttatca
    17041 tcaatatgca aaggacattg aattgtgtga acgttttggt gtaaatggtc taagattatc
    17101 cattgcttgg agccgcattt ttcctgatgg agctgggaaa ccaaatccag aaggaatcgc
    17161 tttttatcat cgtgtgttcg aagaatgtaa gaaaagaaac gtaacgccgt ttgtgacgtt
    17221 gcatcatttt gataccccta aacgtttgtt tgaccatgga gattttttga atcgagaaac
    17281 aatagaagca tttgtttcct atgccatttt ttgttttcat gaattcaaag aagtcaaggt
    17341 gtggagtacc tttaatgaaa tctatccagt tgcaaccaat caatatttgt taggtgtttt
    17401 cccaccagga atcaaatatg attttacaaa gatcgtcgcc tgtcttcata atatgatggt
    17461 tgctcatgcc cgtgtagtga actatttcaa agaaaacgaa cttccgggtg aaattggtgt
    17521 agttcactca ttagagacga aatatgcggc aacagacgcg ccggaagata agcatgctgc
    17581 ctttttagac gatgcattgt cgatccgttt cttattagat gctacctatt taggctatta
    17641 ttcaactgaa accttgactg ctcttgatga gatatgtgaa gcaaatcagg ccagctatca
    17701 ttttcctgaa gaagatttcg ttgaattgaa aaaagcatcc acgcgtaatg actacttagg
    17761 gatcaatcac taccaatgcc attttgtcaa agcttacgat ggagaaaatg caatccatca
    17821 taacggtacg ggtgaaaaag ggacctctgt ttataaagtg aagggaatcg gagaacgtat
    17881 ttataaagaa ggaattcctc gaactgattg ggactggctg atttatccag aaggtctata
    17941 tgacttgttg ctgcgaatta aaagcgatta cccacattac aacaaaatct atatcactga
    18001 gaacgggatg gggtataaag atcagtttga agatggcatt attatggatc agccgagaat
    18061 cgactatttg agagtctatt tggaatcctt aagcaaggcg ataacagccg gggtaaatgt
    18121 gaaggggtat tttttgtggt cgcttatgga tcttttctca tggacaaatg ggtataacaa
    18181 aaggtatggc ttgttttatg ttgattttga aacccagaag cgttacccaa aagaatcagc
    18241 ttactggtac aagttggtca gtgaaaccaa aacgattatt taataagtga taatggagga
    18301 agaaaagatg aataaagagg aattacaaat gcttggtttt gagatcgttg catattcagg
    18361 cgacgctcgc agtacattat tgaaattatt gaaagaagta agacaaggaa actttgaaca
    18421 tgttgattcg gcgttgaaag aagccgacga aaatttaacc cttgcacata attcgcaaac
    18481 aaaaatttta gcggaagaag catctgggaa agagatggag atgggattca tttttatcca
    18541 tgggcaggat catttaatga ccactttatt gctgagagat ctgattcaag actttattgt
    18601 actgtacaga cagaatcaag gataggagaa gaacgctatg gatggaatca ttaaacaaat
    18661 cgaaaaaggg aaaccatttt ttgaaaaaat ctcacgtaat agttatttag gagccgttcg
    18721 tgacggattt ttaacagcga tgccagctat tttattttca agcattttca ttttgattgc
    18781 tgcggttcct gagatttttg gttaccaatg gcctgaatct gtctccacat ggctatggaa
    18841 agtctataat tattcgatgg gtgttgtagg gttactcgtt tcagcaacca ctgctcgctg
    18901 cttggctgat tcgatgaatc gtcgcttacc gaaaaacaaa gtaatcaaca ccacctctgt
    18961 gatgctggcc tctgtggtaa gtttcctgtt gttaagcgtc tctccgattg aaggtggatt
    19021 ttcaacggaa tatatgggga caaagggact actggcttcc tttgtcgctg catttttaac
    19081 agttaattta tataagtttt gtgtgctgaa agatattacc attaaaatgc ctaaagaagt
    19141 tcctggaacg atttcgcaaa ccttccgaga tatttttcct ttctcttttt cagtatttgc
    19201 ggccgtttta attgatttag gcattcgaca aatcttccaa atctcatttg cagaagcaat
    19261 cattacggtg ctgcagccgc tatttacagc agctgacggg tacttaggaa tcgctattat
    19321 ctggggagcg atggcgctgt tttggtttgt cggtgttcat ggaccgtcga tcgtggagcc
    19381 ggcaattgcg gcaattatct atgccaatgt ggaaaccaat ctgcaattgt tcaattccgg
    19441 tgaacaagct tctaaagtac tgacggtggg tttagggaat tttgtaggaa ctatgggagg
    19501 aactggggca acattggttg ttccttttat cttcctactc tttgctaagt ctaagcagtt
    19561 gaaggcagtt gggaaagctt cctttattcc agtaagtttc gctgtcaacg aaccattgct
    19621 atttgcggca cccatgattt tgaaccctta tttttttatt ccatttttgt taacacctgt
    19681 tgtaaacgtt tgcctgttca agttttttgt cgatgtattg ggcatgaaca gctttatgta
    19741 cgttttgcct tgggcaactc cagcaccgat cggtttggtt ctaggaacgg gcatgggtat
    19801 cttagctttt gttctagcag cggttctaat cgtcgttgac ttcctgatct atctaccatt
    19861 ttgcaaagca tacgatgctg tcttagtaga gaaagaagca caaaaagcag aggtgatcgc
    19921 aaccgaggaa ggtgcttctg ccgatgtacg tgaggaagta cctgtggcag cgagtcaagt
    19981 tatcagcgat gcaaataaag aaatcaatgt gttggtactt tgtgctggcg cagggacaag
    20041 tgcgatgtta gctaatgctt taaaaaaagg tgcatctgaa tcgaaagcac cgatcagtgc
    20101 aatggcgggt gcttatggtt ctcattacga aatgctgcag gattttgata tggtggtctt
    20161 agcaccgcaa gtcaattctt actatgatga tatcaaagaa gacaccgatc gcttaggaat
    20221 caagctggtt gcgacaaaag gagcagaata tatcggatta acgagagatc ctgaaaaagc
    20281 tgttcagttt attctgaacc aatttcaata aaggaggagc cataatgaaa atgggaattt
    20341 ggttgcgtaa agctgtttta tttgcagctg tgttaggggc tttgggggct gtttcaaaaa
    20401 ctgttgaagc atctgccagc gaatttattc gcggagcaga tatttcgatc ctgtcagata
    20461 tggaaaaatc tggtgcaaaa tattatgaag acgatatttc aaaagatgcc ttagagattt
    20521 taaaaaataa tggtgtcaac tatgttcgac tgcgtttgtg gcaggatcct tataatagta
    20581 atggagaaag ttatggagca gggacaaatg atctggaaac gacgattgac cttgcaaaac
    20641 gagcaaaaaa tctgggactt aaggtgctgc tggattttca ctacagtgat ttttgggttg
    20701 atcctgggaa acagaatctt cctaaagcat ggcaaggtct gacctttgaa gaaatgaata
    20761 cggcattgta cgactataca aagaacgttc tgtcggaaat gaagcagctg gacgtttatc
    20821 ctgatatggt tcagatcggc aatgaactga atagcggaat gctctggcct tatggcaagt
    20881 cttggggaga aggcggggga gaatttgatc gattggctgc ttttttgaag tctggtatcc
    20941 aagctgttcg agacactcaa cctaaaacaa ctccagtaat gctccactta gctgatggtg
    21001 gcgatacagg agcatttact tggtggtttg atgaaatcac gagtcgaggt gtgtcatttg
    21061 atttaattgg agtgtcgtat tatccgtatt ggcacggttc aatgaatgaa cttcaaacca
    21121 atatgaatgc gatcagccaa cggtatggta aagaagtgat cgtagttgaa acagcttatg
    21181 ggcatacaac agcgaatgcc gatactatgc caaatgcttt tggtgaagcc gaagcagctg
    21241 cggggggata tgaaccaaca ccgacaggac aagcagagta tttgctggat cttgccgatc
    21301 ggattcaggc agtaccgaat aatcgcgggg cgggcttctt ctattgggaa cctctttggt
    21361 acaacggaaa tgtgagttgg gcaacacaag caggtatgaa ttatctcagt gttcaatcca
    21421 ctatgggaaa cgaatgggac aaccaagcga tgtttgattt tgctggaaac gccttgccaa
    21481 gcttgcgtgc gtttaaacaa gcaggggcgc aaataaatct agttaaaaat gcaagtttcg
    21541 aaagcgatgg accaacgacc agtccttcca attggcaaac ctggtttcaa caaggaaccg
    21601 ctaagggtac gatcaaaacg gaagcgggca ctttttttgg ggactacaaa ctaacttttt
    21661 ggcaggatca agcatacgag gcatcagctt atcaaaatgt tagtggcata agcaaaggaa
    21721 cttacacatt gagtgcctat gtaatgtctg ggggagagtt tgatactaat cagttatata
    21781 tcaaaaatta tggtggagcg gaactaaata ctgcggttgt taaaacaagt gaatggacaa
    21841 aaattacaat caaagacatt ccaattacaa caggtgtttg tgaaattggg gtttatagca
    21901 aggcttcagg aaatgcttgg acgaacgttg attttgtttc attggtgaaa caatagactg
    21961 cggatcgttt cgattcaaga tcggaggttc ccttcagcca catcgttagc gtagaaggca
    22021 ggaatcgaac ctgcacctcg cctttgccaa aaataaccag aaacgatttc cagtcatttt
    22081 taccaaaacg agtaaagcac cagacttcat ctacactttg tattatgcta aagagagttc
    22141 aacgatttcg taagaagcaa tgaaaaaatt gcaaaaagtt gtgcagataa cataaagttt
    22201 gtttaagaaa gggtaacctt agaattccgt cgtgaatatg atttgagcac ttagatggat
    22261 agaaaaaagt tctcggaaaa cagttcgttt ttcgagaact tctttttatg ataagaatga
    22321 aacaaattaa cttatattat agtctctttt ggtagggaac catcttattt ttaatgaaaa
    22381 tcaagcattt tagctattga agaatgttga tttataggga ttccccctcc atattatgtt
    22441 ggctctttat tcccactcca ctgttgctgg tggtttagaa gtgatgtcat acacgatacg
    22501 gttgacgtgg gctacttcgt ttacgatacg tacagagatt ttttgcaaga cttcccatgg
    22561 gatacgggca aagtcagcgg tcattccgtc gattgaagtt acagcacgga taccgactgt
    22621 gtagtcgtaa gtacgtccgt cacccataac accgacagag cggatccctg gaagaacagt
    22681 gaaatattgc cagatatcac ggtcaagtcc agcagctgcg atttcttcac gcaagatagc
    22741 atcagattcg cgtacgattt ctagcttgtc ttcagtgatt tcgccaagaa cacgaatacc
    22801 aagaccagga ccagggaatg gctgacgcca aacgattgaa tcaggcatgc ctaactgagt
    22861 ccctaattca cggacttcgt ctttgaataa tgtgtttaat ggttcgatca attcaaattg
    22921 catatcttct ggcagtccac ctacattatg gtgagatttg atcgtctgtg ctgtttctgt
    22981 accagattcg ataacgtcag tatacaacgt tccttgtgct aggaaagaga cgccttcttc
    23041 accagcaagt tttgttgctt cgtcatcaaa aacatatacg aattcattcc caatgatttt
    23101 acgtttttgt tctgggtcag atacaccttt caacttgtct aagaagcgat ctcttgcatt
    23161 gactttgatg atgttcaagc cgaattttcc gcctagactt tccattactt gttccgcttc
    23221 gcctttgcgt agcagaccgt ggtcaacaaa gatagatgtc aattggtcac cgatcgcttt
    23281 ttgtaaaaga accccaacga cactagaatc aacgccacct gaaagaccaa gcaagacttt
    23341 tttgtcacca acttgttcac ggattttttc tacttgcata tcgataaagt tatccattgt
    23401 ccagttacct tcacagtgac aaacatcaaa ggcaaagtgg cgcagcaatt cgattccgta
    23461 ttcggaatga cgtacttctg catggaattg gataccataa aaattacgtg ttgtgtcttg
    23521 gatagaagca atcggacaat ctttgcttgt tccgactgtt tcaaagcctt caggaacttt
    23581 agttaccaag tcaccatggc tcatccatac tgtttgttgt tttggtgttt ctttaaacaa
    23641 gacagcttga tcgcttgtta cttctaacaa ggctttccca tattcgcggt ttttagcagg
    23701 ctctacggaa ccgccaagtt tgtacgtgat caattgcata ccatagcaaa tccctaatac
    23761 aggaatacct aaattgaaga tctcaggatc gatcccaaat gcattctcat catatacact
    23821 gtttggtccg ccagaaagaa tgattccctt tggattcatc gcttttactt cttctgcagt
    23881 aatgcggtgg ctcaataatt cggaaaagac tccaagatca cgaatacgtc ttgtgatcaa
    23941 ttggttatac tgactaccgt agtctaatac gataatcttt tcaacgttcg tcatatcggc
    24001 aacgtttgtc aaatttatta cccctatccc tttaaatttt atctcaaaat agtcaaacta
    24061 ttttaaaatg ctaatatttt cgcatgaaaa tcgaatcgat gatatgattt tcagttttat
    24121 ggagaattat atcggctctt cctcgtgtag gcaagatata ttcctgtaaa tttttcaaat
    24181 tcacattttt ccatacatct tttgccattt taaaggcttc ttcacgatct ccgatagcaa
    24241 aacgataata ataattctct ggattttgga aagccgtatc cagtaacgca ccaaaacgat
    24301 ccaaatacca tttttcgatc agcacgggat cggcatcgac atagacagaa aaatcaaaaa
    24361 agtcgctgac gtagatttgc tgattcgcag gtaattgaag cgtattgatc ccctcaacga
    24421 tcaagatatc aggctgctgg atcaattcgt acttgtctgg aatgatatca tacacatcat
    24481 gtgagtaaac aggtactttt atctcttcct gaccagattt tacacggttc aagaaatcga
    24541 tcagcatctc catatcataa ctttcaggaa atcctttacg gtccatgatt ccacgctctt
    24601 ttaatatacg atttggataa agaaatccgt cagtcgtgat cagctgaacg tttcttcgtt
    24661 tgaaggtacg agacaaaatc gtctgcagca gtctggctgt tgtacttttt ccaacggcta
    24721 cacttccggc gatcccgata ataaaaggcg gtacttctac gtatttatga agaaataaac
    24781 ctttactcaa gaacaaagat tcaaattctt tcatataaag ataaatcaga tgagcaagag
    24841 gtacatagat atctcgaaca tcctgcatgg aaatgcggtc attcaaactt ttgatattat
    24901 ctagttcatc ttgtgtcaaa ggtgcttgcc cattacgata aaattctcgc cattcttctc
    24961 ttgccacacg gtagtagttc attggatcat tcatattagc ctcctgcgtt ctcccatcaa
    25021 tggaactatt ttaacacaaa ataaacgcaa accccaccac ttaagagaga ttgccgatct
    25081 ttttgtataa tctttataat agaaagaaac ggagtcttat tcttgacttg cgcacggata
    25141 cataaaagga tagactgttg tcatgaaaga aatgagaagg atggaagaca tgacaaatca
    25201 ttactattct gaacgcccag atacggcgca cgattttgaa caatgggctt ttgagttaaa
    25261 aggcagaacc tttcaatttg taacagattc tggtgtattt tcacgtgaaa cagtggatta
    25321 tggttcacgt gtcctgattg atgctttcga ttgggaagag ttacctgatg aaggaaagat
    25381 cttagatgtg ggatgcgggt atggaccgat tgggttagct ttggcatttg cgacacagcg
    25441 gtttgttgaa atggtcgaca ttaatgaacg agcggtaagt ctagcgcaag gaaacgcaaa
    25501 gcgtaaccaa atcgaacatg ttgatatcca tcaatcgaat atctatgaag cagttcatga
    25561 agaaacctat gcagctatcg taagcaatcc gccgatccgt gctggaaaaa aagttgtaca
    25621 tgaaattttg acaggcgcat atcctcggtt gaagaagggc ggtacactga caattgtgat
    25681 ccagaagaaa caaggagcgc cgagtgcgca aaagaaaatg gaagaaacat ttggtaatgc
    25741 agaaatcgtc acaaaagata aaggatatta tatcatcaaa agtgtgaaag aataactagc
    25801 tgaaaaatag tggagcgacg aaagagtgga actgggcgtg catgtacggg tacgtatcag
    25861 ttcttttttt gttgagaagt ttttaaaaac aaagaactat tttttcttca aaaagaaata
    25921 gtaggaacag agtcgttgtt ttttacgata aaataaataa gatacagaac ttgtatagaa
    25981 ggctgccaag tcggtagata aaggaggttt ttatcaaaaa acatactttc cttttttctc
    26041 tattcttttc ttgggggttt tggtacactg atagggaatt tagatagaag ggagccaata
    26101 ggatgaagct gaccatcaga gatatcgcag aaatggcagg cgtatcagta acaactgtct
    26161 cacagatttt gaataacaaa ggaagcagat ttagtgataa gacaagaaaa aaagtgttgt
    26221 cgatcgtgaa tgaacatcat tataagcccg attatttcgc ttcaaatgtg atcaatcgac
    26281 attcaaagac catcggaatg atcgtccctg atgtcactga tttcttcttc tccaaactga
    26341 tcgaaggtgt agagagctat ttgaatcctt tgggctatgt gatcatgtta tgcaattctc
    26401 gtcatagcca agaaaatgag atcaagtatt tacaagagct ttcccaccgc tcagtggacg
    26461 gaatcttgct ggccacacca aatattttac ctgagaaata tgcattagac agcggttttt
    26521 atcaaaaaat gccaatcatt ttaatcgatc gcggattgaa tcgtcgggat aacggacggc
    26581 ttatcgtaaa ggaatatgag ggcgcctatc aagctgtttc gctgtttatt gaaaatggcc
    26641 atacgaagat cggcatgctg aaggaaacca ctggatacta tcaattagaa gaacgtttca
    26701 acggatatcg tcatgcgctg aaagatcatg gcctgccttt taatgggaaa tttgttgaac
    26761 atggagagtt gactgtccaa ggtggatata ctgcatcaaa aaaattactc aaacataaag
    26821 atatcacggc tattttttgc gggaatgatg ccatggcgat cggatgctat caggcgatcg
    26881 atgaattggg caaaaaaatc ccagaagata tctcagtcat aggattcgat ggattaaagc
    26941 tgtcagaata catgattccg caattgacga cagtgcagca gccaagtttt gatattggat
    27001 tttatgctgc acgtttcctg atcgatacga tcgaatttcc tcaaagaaaa gttccgaaca
    27061 aagtgttcga aacaaaatta attattcgtg agagcgtaaa agtattgaca aagggctaac
    27121 tcggcggtat attgcttatg taagcattta caaaggctag ttagtgcttt ttttattttt
    27181 agtaaaccag tttactaaag tggtttacct ttcctaaaaa taatgtataa taccgaatga
    27241 agacaaggag gatcaggcaa tgcgaatggt ggatctgatt gaaaaaaaga gggatggaaa
    27301 cgagctgtcg aaagaggaaa tcgagtacat cgtcacgaac tatacgaatg gaaagattcc
    27361 agattatcaa gtcagtgcat tattgatggc aattttttat caagacatga caaatgaaga
    27421 aatcacgaac ttaacattgg cgattgctaa ttctggtgat gtcatcgatt tgagttctct
    27481 tgaaggaata aaggtagata agcattcgac aggtggcgtt ggtgacacga ccacattgat
    27541 tttagccccc ctagtagcta gtgtcggagt gacagtggct aaaatgtctg gacgcggtct
    27601 aggttacaca ggtggtacac tagacaagct agaagcaatt cccggatttc agatcgagct
    27661 ttcggatgaa gaatttgtac gcattgttaa tgaaagtaaa gtagcggtaa ttggtcaatc
    27721 aggaaacttg gcaccggcgg acaaaaaatt gtatgccttg cgtgacgtca cagcgaccgt
    27781 tgattctctt ccgctgattg ccagttcgat tatgagtaaa aaaatcgcgg caggagcaga
    27841 tgcaatcgtt ttggatgtga ccactggaga cggtgctttc atgaagaaca tcgaagatgc
    27901 aagacgtctg gcaaagacca tgacgagcat tgggaaactg gctaaccgag aaacagtggc
    27961 ggttatctca gatatgtcag aacctcttgg cgaagctatc ggaaatagtc tagaagttgt
    28021 cgaggcaatc gaaacattac aaggaaatgg tccagaagat ctagtagaaa tgtgctacgc
    28081 cttaggaagc caaatggttg ttcttgctgg caaagctaag acaaccgatg aagcaagaac
    28141 gttgcttcaa gaagctctgg aatcaggtaa agcgttagca aaattcaaag aaatgatcca
    28201 aaatcaaggg ggagacccag cgatcgtgga acatccagaa cgaattttga ctgcacgcta
    28261 cacaatggag cttcctgcta aacaaagcgg agttgtgtca aaaatcgtgg caaatgaatt
    28321 aggaattgct gcaatgatgc taggtgctgg gcgtaaaacc aaagaagaag atattgatca
    28381 cgctgttgga ttgaaactgc ataaaaaaat tggtgacact gtgacaaaag gtgagtcact
    28441 attgacgatc tatagtaacg acgaagaaat cacttctgtc attgaattat tatataaaaa
    28501 tattgaaatt ggtgaatcgg caatgaagcc aacgttgatt catgacatca tcacagaata
    28561 aaggaaaaaa gcggacttta ccgttttaaa gaaaagggga aaagaaatgg aactaaaccg
    28621 aatgatcgac catactattt tgaaagcaga cgcatctaaa gaagctgtga tgcaaattat
    28681 cgaagaagca aaaaaatacc atttttattc tgtctgcatc aatccagcat gggttgcgct
    28741 agcgaaagaa caattacaag gtgagccagt agccgtatgt acagtaatcg ggtttcctct
    28801 aggagcaaac acacccgaga caaaagcatt tgaaacaaca gatgccatca ataacggtgc
    28861 agatgaagtc gatatggtca tcaatatcgg tgctttgaaa tcaaaggatg atcaacaagt
    28921 ccaaaaagat atcgaagcag ttgttgaagc agcaaaagat cgtgcgcttg tcaaagttat
    28981 tattgaaaca tcgttattag atagagaaga aatcatccga gcttgcgaaa tagcaaaagc
    29041 tgcaggcgct gattttgtca aaacatcaac tggtttctca acaggcggag caaaggtaga
    29101 ggatgtccgt ttgatgcgtg aaactgtagg accagaaatg ggtgtcaaag cttccggcgg
    29161 tatccataac gaagaagaag caatggcaat gatcgaagct ggtgctacaa gaatcggaac
    29221 aagcgcagga gtagcaatcg tatctggttc aactggtgaa ggctattaat tttttcaaag
    29281 gagaagctca tggcagaact caaacaagaa tggatcaaca cagctattga agcgttagat
    29341 aaagcctatg ttccttattc ccattttccg gtaggcgctt gtctcgtaac ggaatcaggc
    29401 aagatttatc aaggcatcaa cattgagaat gcatcatttg gattaacgaa ttgtgccgag
    29461 cgcacagctt ttttcaaagc agtatctgaa ggagaaaaaa catttacgca tctagtcgta
    29521 gcggggcaca cccccgatcc tatctctcct tgtggtgcat gtcgacaagt aatggcagaa
    29581 ttctgttccc ctgatatgcc ggttacgcta gtaggagaca atggtgtgac gaaggcaacg
    29641 accgttcgtg cactgctgcc ttatgcattt actgaaaaag atctataact catgttcatt
    29701 cagtcagctg actgttgaaa aataaaacaa ttattttagg aggctttaca gaaatgaaaa
    29761 aagcaaaatt atttggttta ggtgctgtcg cactagcagc agggttattt ttaggtgcat
    29821 gcggcaacaa cggctctact gattcatccg gtggcaaaag ctcatcagac acaacaactg
    29881 cagcattgat cacagacaca ggtggtgtag acgaccgttc attcaaccag tcagcttggg
    29941 aaggactaga aaaatggggg aaagatcaag gactttcacg aggaaatgat ggcttccaat
    30001 atttccaatc ttcaaatgaa tcagattaca tcccaaatat tgaccaagca ttgaatgctg
    30061 gattcaaaac gatttttggt attggttata aactaaaacc agcgatccaa gaacaagcaa
    30121 caaacaatac aggtacgaac tttgttatta tcgatgatgt catcgatgga ttagataacg
    30181 ttgtatctgc aactttcaaa gacaacgaag cttcttatct tgcaggtgtt gcagcagctt
    30241 atacgactga aacaaacgta gtcggcttta tcggcggtgt aaaaggtgaa gtaatcgatc
    30301 gttttgatgc tggattcaaa gccggtgttg atgcaggtgc gaaagaatta ggaaaagaaa
    30361 tcaaagtatt gaatcaatat gctggtgact tctctgctcc agataaagga cgttcaattg
    30421 ctcaaggtat gtatgcacaa aacgcagata tcatcttcca tgcttcaggc ggtacaggta
    30481 acggtgtatt ccaagaagca aaatcattga acgaatcagg cgacaaaaaa gtttgggtta
    30541 tcggtgttga ccgcgaccaa tcagacgaag gcgaatacac attaaacggc gaaaagaaaa
    30601 acttcacatt gacatctaca ctgaaagcag ttggaacagt agtagaagat ttggcacaaa
    30661 aatcagcgga cggtaaattc cctggcggcg aacacactgt ttatggattg aaagaagacg
    30721 gtgttggtct aacagaagga caactttctg acgaagcgaa aaaagcagtt gatgaagcaa
    30781 aagaaaaaat catttcaggt gacgtaaaag ttccagaaac tcctgaagaa aactaaaacc
    30841 atttctatag ccttgttaga cacatgtttg acaaggctat ggtttgatta gaacaagaat
    30901 tgttcattta tccaagctgc cttgtgacag tttggataag ggaacaactc cctgaagtaa
    30961 tgtttgtttc aaaagaagaa cgctcactaa gcgtgaatct tagtcaatcg ttgccctaga
    31021 tagaaatcgt taggatgtga aaaaaaggtg gttcaagaaa atattgtcat agaaatgcag
    31081 aatattacca aagaatttgg aacattcaag gcaaatgaca acatcaattt acaagtaaag
    31141 gcaggagaaa ttcatgcgtt gcttggagaa aacggtgctg gcaaatctac attgatgaac
    31201 gtgctttccg gattattaga gccgacatca gggaaaattt tgatgcgtgg gaaagaagta
    31261 aagatcacaa gtccgaccaa agccaaccaa ttagggattg ggatggtcca tcagcacttt
    31321 atgcttgttg atgcctttac tgtaacagaa aacatcgtgt tgggaagcga gcctagtcgc
    31381 gcagggatgc ttgaccataa aaaagcacga aaagagatcc aaaaagtttc tgaacagtat
    31441 ggattgtcag tcaacccaga tgcttacgtt cgtgatattt cagttggaat ggaacaacgg
    31501 gtagaaattt taaaaacact ttaccgagga gcagatgtac tgatttttga tgagccgaca
    31561 gctgtattga cccctcaaga aattgatgaa ttaatcgtga tcatgaagga attagtcaaa
    31621 gaaggcaagt cgatcatttt gattacgcat aagttagatg aaatcaaagc agtagctgac
    31681 cgctgtacag ttatccgccg tggaaaagga atcggtacag tcaacgttaa agacgtaacc
    31741 tcacaacaat tagccgatat gatggttgga agaacggttt cattcaaaac gatgaaaaaa
    31801 gaagcgaagc ctcaagaagt cgttttgtct attgaaaatc tagtggtgaa agaaaatcgt
    31861 ggattagaag ccgtgaaaaa cttgaactta gaggttcgtg ctggcgaagt acttggtatc
    31921 gctggaatcg atggaaacgg gcagtcggag ttgatccaag ctttgactgg tttgcgaaag
    31981 gcagaaagcg gacatatcaa gctaaaaggg gaagacatca ctaataaaaa accccgaaaa
    32041 atcactgaac atggtgtagg acacgtgcca gaagaccgtc ataaatacgg gttagtccta
    32101 gatatgacat tatctgaaaa tatcgcacta caaacctatc atcaaaaacc ttacagtaaa
    32161 aacggcatgc tgaattattc agtaatgaat gaacatgcca gagaattgat cgaagaatat
    32221 gatgttcgaa caacgaatga acttgttccc gcaaaagctt tatcaggcgg aaatcagcaa
    32281 aaagcaatta tcgctcgtga agtcgaccga gatcctgatc tgttgattgt tgcaaatcca
    32341 actcgtggac tggatgtagg tgcgatcgaa tttattcata aacgtctgat cgaacaaagg
    32401 gacaaataca aagcagtgtt actgatcagt ttcgaattag aagaaatttt aaatgtttcg
    32461 gatcgtattg ctgttatcca tgaaggagaa attgtcggta tcgttgatcc gaaagaaaca
    32521 tctgaaaatg aattaggtct attgatggcg ggctatacct tagaagaagc acgaaaagag
    32581 ttagaaaagg gggctggcgc acatgaatga tcgcagcgaa aaattccgta atttattagt
    32641 gcctgtactt tcagttgttt taggattgat cttaggcgcg atattgatgg ctgcttttgg
    32701 ttttcagccc atccaaggtt attcttctat gctagatgca gcccttggtt cgcaaagagg
    32761 gataggtgaa acgttaaggc aagcaacgcc gttgattttt acagcattag gtttttctgt
    32821 agctaactca gctgggtttt tcaatattgg gctttctgga caagcacttt gcgggtggat
    32881 cgtcagtgtc tgggtggcac ttgcgtttcc agatctgcca aaagttgttt tgcttccgtt
    32941 atgcgtgatc ttaggtgcct tagctggtgc gatggcagcg gctgttccag gtttacttcg
    33001 agcatttttt ggaacaagtg aagtgatcgt aacaatcatg atgaactata tcttattata
    33061 cgtaagcaca tttgctttac atgaagtgat gcctgaaagc tatcgctcaa gtttggactc
    33121 ttccaatatg atcagtcaaa atgcctcact gcggttacca tggttaacac aagcttttgg
    33181 cggctctcgc gtaaactcag gattattttt agcaatcatc gcgcttattt tcgtttggct
    33241 gctgatgaag aaaacgactt taggatttga aatccgttct gttggattga atccttttgc
    33301 ttctgagtat gcaggaatga gtagtaaacg tacgatcgtt ttgtcgatgg tcatttctgg
    33361 cgctttggca gggcttggcg gtgtggttga aggattagga acgtatcaaa acttctttgt
    33421 tcaaacgact tcgctatcta ttggatttga cggaatggct gtttccttgc ttggttctgg
    33481 atcagcaatc ggtattcttt tatcagcgat cttgttcagt attttgaaga tcggtggact
    33541 tggcatgcag acaggagcag gtgttccgtt tgagatcgtc aatgtatcga ttgctttgat
    33601 tatcttcttt gtcgggatca acttcctgat tcgtttcgtc atggctaaag tcttccaagg
    33661 gaaaaaacaa gaagagatcg ttgcgacaat agaatcgaaa ccaacgaatc aaaaccatga
    33721 agggggcgaa ctataatgtc gactatcgaa ttaattgcct tgatccttac ttctacactg
    33781 gtttattcaa caccgctaat tctaacgtca ctaggcggaa ctttttctga acgaagcggg
    33841 atcgtaaacg tagggctaga gggaatcatg gtcatgggtg cttttagttc catcgttttc
    33901 aacttgacga tgagtccatc acttggttct atgacaccat ggatcgctat tttagtgggt
    33961 ggcgtcgtag gtatcctatt ttctctgatt cacgcagtag caacagtcag tttgcgtgct
    34021 gaccatatta tcagcgggac agtaattaat ctgatggcac ctgctttagg tgttttcttg
    34081 atcaaagcat ggtatggtaa aggtcaaact gataacatca cgcagaatct ggggtatttt
    34141 tctttcccag gattagcaga tattccggtc attggaccaa ttttctttaa aaatacattc
    34201 ttacctgctt attgtgctat tttgattgct gtcctagctt gggtgatcat cttcaagacg
    34261 aaattcggct tgcgcctccg ttcagttggt gaaaatcctc aagctgccga cacattaggt
    34321 atcaatgtat atgctatgcg ttattcaggc gtactgattt ctggcttgtt aggcggtatg
    34381 ggcggtgctg tttttgctca gtcgatttcc ggtaactttt cagctggtac gatcgttgga
    34441 caagggttca tctccatggc tgctatgatc tttggtaagt ggaatccttt aggggcaatg
    34501 ggtgcctcat tgttctttgg ttttgctcaa agcttgagta tcattggcgc acaattacca
    34561 gttatttctt cgattccgcc agtattgctg caaattgctc catatttgct gacaatcatt
    34621 gtgctggttg ttttcttagg gaaagcttct ggtccaaaag caaacgggaa gaactatatc
    34681 aaatcaaaat aatcttttag cgaataaaaa gggtgggtta cgggaagtgt ttttcgtctc
    34741 gccctttttg ttttaaaggc aataaaaata aaaagaaaga aggaataatc atgtttaaac
    34801 gcgtacatct gatcgtcatg gattcagtag gaattggaga agcaccagat gccgataagt
    34861 tcggtgatgt tggttctgat acattaggac acattgcgaa agaagcagga ttgaacgttc
    34921 cacatttaga gcagcttggt ttaggaacga tccgtcctct tgaaggtgtg gaatcagtga
    34981 aagatcatca aggctatgcg acgaaattag aagaagtttc tgtagggaaa gatacgatga
    35041 caggccactg ggaaatcatg ggattgaata tcaaaactcc atttcgtgtg tttcctaatg
    35101 gattccctga tgatctgatc aaacaaatcg aagaattttc tggccgtaaa gtcgtatgta
    35161 acaaacctta tagcggaaca gctgttattg acgattacgg tgaacaccaa atgaaaacag
    35221 gcgatttaat tgtatatact tctgccgatc ctgtccttca gatcgcggca catgaagaaa
    35281 tcattccttt agaagaatta tatcggattt gccaattcgt tcgtgatata acaaaagatg
    35341 atccgtatat gattggccga atcattgcac gtccgtacgt gggtgaacca ggagacttca
    35401 cacgaacaag caatcgccat gattatgcgt tgaatccatt cggacacaca gtccttgatt
    35461 ctttgaaaga agcaggaaag gacgtgattg ctgttggaaa gatcaacgat attttcaacg
    35521 gacaaggaat cactgaatct gtccgcacga aaagcaatat ggatggcgtt gaccagctgc
    35581 tgaaagttat gaaaaacgat ttttcaggaa tcagctttac caatttagta gattttgatg
    35641 cattatacgg tcatcgtcgg gatgtagtcg gctatgcgca tgcgattgaa gaatttgact
    35701 tacgaattcc agaattgctt gaagcgatgg aagaagacga cttgctaatg attacagccg
    35761 atcacggaaa cgatccgacg tttactggta ccgatcatac gcgagaatat gtaccgttat
    35821 tggtttacag taaaaaaatg aaagaacaag gggcattgcc tcaaggatat tattcagata
    35881 tttcagcaac gattgctgag aactttagtg tttcttcgac tgaaaatggc gaaagcttct
    35941 tgaaattatt aaaataatct ttttaaatag gagaaagcaa atgaccaagt taagcgagat
    36001 gttacaagaa acgacccagt ttatccttga taaaggagta aaagaaattg attttggttt
    36061 gattctaggt tcaggattag gtgaattagc agatgaaatc gaagatgctg taatgatttc
    36121 ttatgatgag atcccgttct ttcctgtttc gacagtagtt gggcatgcag gaaagctagt
    36181 ttatgggtct ctggcaggca agaaagtgtt agccatgcaa gggagattcc actactatga
    36241 aggtcattcc atgcaaacag tgacctatcc agtacgtgtg atggccggac taggggccca
    36301 ttcagtcatt gtgactaatg catgtggtgg tgtcaacgaa tcatttgtac caggagattt
    36361 gatgctgatt accgatcata tcaattttac tggtgaaaat cctttgatcg gtccgaatga
    36421 agatgcaatg ggccctagat ttccagatat gagtcaagct tatacgcctg actatcaagc
    36481 aacagcaaaa gcagcagcag aaaaactagg tttggatctt aaagaaggcg tatatatggg
    36541 ctattctgga ccaacttatg aaacgcctgc ggagatccga atgtctcgga caataggagc
    36601 cgatgcagta gggatgtcga ctgttccaga agtcatcgta gcagctcaca gcggattaaa
    36661 agtgttagga atctcttgta ttaccaactt agcagcaggt atgcaagcga atctgagcca
    36721 tgaagaagtt gtagaaacaa ctcagagagt caaacaatct tttaaagcat tggttaaaga
    36781 aacattgaca ttattgtaat aggaggaaca ataaaatgag tgtgcatatt gaagcgaaag
    36841 aaggcgagat cgccgataag attttacttc cgggagatcc tttgcgagct aaatatattg
    36901 cggagacttt tttggaagat ccagtttgtt acaatcaggt acgcggtatg ttaggcttta
    36961 ccggcaaata taaaggagaa cgtatttctg ttcaaggaac aggaatggga atgccatcag
    37021 ccaccatcta tgcccatgaa ttgatccagt cgtatggtgt aaagaaattg attcgagtag
    37081 gtacatgcgg tgcattgtca aaagacgtcc atgttcgtga tttagtacta gcacaaggtg
    37141 cagcgaccag ttcttcgatg atcgaaaaaa atttccaagc ctttcatttt cctccaatca
    37201 gtgatttcaa tctattactg aaagcatatg agatagctaa agaaaagggc tatacggttc
    37261 atgtaggaaa tgttctttcg gaagattctt tctacaaaga tgatttgaca gagacgttcc
    37321 aattagctga acttggcgtt ttaggagtgg aaatggaagc agcggctctt tattacttag
    37381 gcgcgaaata ccatgtgcag acattaagtt tgatgaccgt tagcgaccat ttgatcaccg
    37441 gtgaagaaac aacagctgca gaacgtcaat ctacgttcaa tgaaatgatc gaagtaggat
    37501 tggaaacagc gatagcagaa taagaaggaa atgaaaaagc tgccctgcat taagtaataa
    37561 gaacatccaa gcaaaaatag ctcctcatgt ttttgacttg gctggactta ttattgcaaa
    37621 tgtaagcttt tgaacaccgt ttaccaagag gttgtgaatc tgccgtttaa ctctgagtca
    37681 caaggaacaa tttcaaaaaa cagcttttca tgtttgatga atattgtgac ttgtgaccga
    37741 gaagttggca ggagaaaacc gtttatacga aaaaagggac tgtgacaaat cgtgtcacag
    37801 tccctttttt atagtgtttt ttataggtag tattttttag caactgttaa gtcatcattt
    37861 aattcataaa caagtggttg acctgttgga atttcaagat ccatgatgtc ttcgtcagag
    37921 ataccttcga tatgtttagc tagggcgcgt aatgagttac catgtgcagc tactaaaaca
    37981 gttttgttgt ctagtaatgc tggagcaatt tcatcttgcc agaatggcaa agcgcgttct
    38041 aatgtcactt tcaagttttc tccaccagga atatcgcgtt tgtctaacat tgcgtaacga
    38101 cggtcatttg ctgcagaacc ttcgtcagtt tcttccatta atggaggaag agtatcgtaa
    38161 gaacgacgcc agatgtgcac ttgttcgtcg ccgtattttt cagctgtttc ttttttgttc
    38221 aaaccttgta atttaccata gtgacgttcg tttaagcgcc atgatttgat ttgtggtacc
    38281 caaagttgat ctgaatattc taagatcaag ttacatgttt tgattgcacg agttaaaaca
    38341 gaagtgtaag caacatcaaa ttcgattcca gcttctttga ttttgcgtcc gccttctttt
    38401 gcttcttcga ttccttctgg tgctagattt acatcagccc aaccagtaaa ttggttcaat
    38461 gcattccatt cactaagacc gtgacgagaa aaaactaatt ttggcatgtt tagctctcct
    38521 tttaagatag gtttatattt ctgaaatttt cagttctgtt ttattgtaca attttttgga
    38581 agagatttcc atcgaaaaat tagataagat tctatgagaa aacaagtaga gaatataaaa
    38641 aaacgaacag tgcccacgca actgttcgtt tttaggtatt agatgcataa ttgctcgatt
    38701 tctttttcag gtaaattgat atatttataa catgttccaa ctgaaacacc gcattttgaa
    38761 gaaataaatt ggatcgtttc ttttttttca taatagagac gtcggatttt tttgatcgtt
    38821 tttgcatcga tttttggtct tccgccgatt tttccttttt tacgagcttc atctaatcca
    38881 actaatgtac gttctttgat caatgcgcac tccatgtttg ctaggttttc cattaattgg
    38941 aaatagattt ttcccatttc gcgcgtatcg attccttcat caagactaat caagtgcagc
    39001 ccgcgatctt tgaataattg cgtgagttct gttaattgcc gcgtagattt gcctaatcga
    39061 tgaagttggc aaatgactag tgcatcgcct tgttgcatgt cagcgatcac tgactccaaa
    39121 tgaacagcag tagaatcatt ttgttccact tcatatgtct catggaaaat ttcttgacaa
    39181 ccaaagtcag ataattgatc aacctgagtt gttaaatcaa cgtcatttat ggttgtgcgt
    39241 gcataaccaa taattttcat ggtgattcct ttctagcagt gattttctaa ctggatataa
    39301 cagtaaaaat gtagcataaa gtacgtcaaa aagatagttt tttcgcaaat tttccgctgt
    39361 ctttttttat tggatgatca agcagttttt ctttatttac gacggattgc gtcaagaatc
    39421 tcaacgcctt tttctgagcc gacaactact ttagaaacca tgtttaggaa aagcccatgt
    39481 tctactaccc caacaagttc atctaaatag gtagctaagc tttctggctg ttcgatgact
    39541 tctagatgca gatcaatgat gtaatgacca ccatctgtgg ttaagacttc tccgttttcg
    39601 tctgtacgca agacgggttg gaatcttttt tcttcaaaaa tatgaagtag ctgttgggag
    39661 ccataaggga tcacttcaac tgggagtggg aacttcccaa gtttatcgac taatttagaa
    39721 gaatcaacga tccaaatcgt ttcttttgag tacgtagcga ctattttctc gaaaagcaaa
    39781 gcagcgccgc cgcctttgat cccttgaaaa tcagcactga tttcatcagc accgtctatt
    39841 gtcaaatcga ctacggggac ttcatcaata ctctttaacg gtattcctaa tttttccgct
    39901 tgttcttttg tcgcatttga agtagtaact cctgtgatac gtaaaccttc ttcacgcata
    39961 cggcgaccaa tctcttctac catataatag gcggttgaac cggtcccgag acctacgatc
    40021 atcccgtcct ttacgaattt cgcggcttca atgccagcta attgttttaa attcatcttt
    40081 gcgtccacct ttttttagtt tgagcatcgt gctttcctca ctattttagc gtgatttacg
    40141 gtaaaaagat accattcttt tttattccaa taaagctttt tcaaaaaaaa ttgcatctct
    40201 tgttgacatg ttttttcatt cgtgatattc taacaaaggt gctttatcta caggtttctg
    40261 tgaagaaacg tgctgactgt ttatcaaagc atatttgata aggatgcaga cattgcattt
    40321 attttttatc acaaaaaaag aaccacctgg atgtgtggaa ctagacgcaa atcgtgggaa
    40381 ggaggaaaca aggaatgcct acaattaacc aattagtacg taaacctcgt aaatcaaagg
    40441 tggaaaaatc taattcacct gctttgaaca aaggatataa cagctttaag aaaactcaaa
    40501 ctaacgtaaa ctcacctcaa aaacgtgggg tagcaactcg tgtgggtaca atgacaccta
    40561 aaaaaccgaa ctcagcttta cgtaaatatg cacgtgttcg tttgtcaaac ttaattgaag
    40621 ttactgctta tatcccaggg attggtcata acttacaaga acacagtgtt gtattattac
    40681 gcggtggtcg tgtaaaagac ttaccagggg tacgttacca tatcgttcgc ggtgctttag
    40741 atactgctgg tgttaacgac cgtaaacaaa gccgttctaa atacggaact aaaaaaccta
    40801 aagcttaatt ttaattatta aacaaatgaa acttgcttct actatataga agtaattact
    40861 atgaacaata tttcggaagg aggagttacg gatgccacgt aaaggtcctg ttgcaaaacg
    40921 tgatgtttta ccagatccta tttataactc aaaattagta actcgcttga tcaaccgtgt
    40981 aatggttgac ggaaaacgcg ggattgcagc taacattatc tataatgcct ttgacttgat
    41041 caaagaatct acaggtaacg atccattaga agtgtttgaa caagcaatga aaaacgttca
    41101 acctgttctt gaagttaaag cacgtcgtgt tgggggttca aactaccaag taccagttga
    41161 agttcgccct gaacgccgcg ttactctagg tcttcgttgg gtagtaaact acgctcgctt
    41221 gcgcggtgaa cacacaatgg aagaacgctt agcaaaagaa atcatggatg ctgcaaacaa
    41281 cacaggtgct tctgttaaaa aacgtgaaga cactcataaa atggctgatg ccaaccgtgc
    41341 gtttgctcac tatcgctggt aagattctct ctgtttggtc ggcttttata agtcgacctc
    41401 agatagtgtc cttattttta gcaactagat agtaaagaga ggagaaacaa ggagaatgac
    41461 cagagaattt tctttacaaa acactcgtaa tatcggtatc atggcccaca tcgatgctgg
    41521 taaaacgact gctactgaac gtatcttgta ctatactggt aaaatccata aaattggtga
    41581 aactcatgaa ggagcttcac aaatggactg gatggaacaa gaacaagaac gtggtattac
    41641 gatcacttct tctgctacta cagcacaatg gaagggtcac cgaatcaaca tcatcgacac
    41701 accaggacac gtagacttca cagttgaagt tgaacgttca ttgcgtgtac ttgatggtgc
    41761 tgtaactgtt cttgatgcac aatcaggtgt tgaacctcaa actgaaacag tttggcgtca
    41821 agcaacaact tatggtgtac ctcgtatcgt atttgcaaac aaaatggaca agatcggtgc
    41881 tgacttctta tattcagtat caactttaca tgaccgtttg caagcaaacg ctcacccaat
    41941 ccaattacca attggtgcgg aagacgactt cacaggaatt atcgaccttg taacaatgaa
    42001 ggctgaaatg tatacaaacg atcttggaac agagatcgaa gaaacagaaa ttcctgaaga
    42061 ataccgcgaa ttagctgaag aatggcgcga aaaattggtt gaagctgtag ctgaaactga
    42121 tgaagaactt actttgaaat acttagaagg tgaagaaatc actgaagctg agttaaaaga
    42181 aggtatccgc cgcgcaacag ttaacgtaga attctaccca gtactatgtg gttcagcatt
    42241 taagaacaaa ggggttcaat tactattgga cgctgttctt gattacttgc catcaccgtt
    42301 agatatccca gctatcaaag ggattgaccc taaaactgat gaagaagtag aacgtcctgc
    42361 agacgacagc gctcctttct cagctttagc atttaaagtt atgactgacc cattcgtagg
    42421 tcgtttaact ttcttccgtg tgtactctgg tgttttacaa tcaggttcat acgtacaaaa
    42481 cgcaacaaaa ggcaaacgtg aacgtgttgg tcgtatccta cagatgcatg ccaactctcg
    42541 ttcagaaatc tctgaagttt acgctggaga tatcgctgct gctgttggtt tgaaagacac
    42601 aactactggg gacacactat gtgatgaaaa gagtctagtt attcttgaat ccatggaatt
    42661 cccagaacca gttatccaag tcgctattga acctaaatca aaagctgacc aagataaaat
    42721 gggtgtggct ttacaaaaac tatctgaaga agatcctact ttccgtgctg aaacaaacgt
    42781 ggaaacaggc gaaacaatca tcgctggtat gggtgaactt aacttagata tcatcgttga
    42841 ccgtatgcgt cgtgaattca aagttgaagc taacgtaggt gcgcctcaag tatcttaccg
    42901 tgaaactttc cgtgctggca ctcaagccga aggtaagttt gtacgtcagt ctggtggtaa
    42961 aggtcaatac ggtcacgtat ggattgaatt tacaccaaat gaagaaggtg ctggtttcga
    43021 atttgaaaat gcgatcgtcg gtggggttgt tcctcgtgaa tacattccag ctgttgaaac
    43081 tggtttgaaa gatgctatgg aaaatggtgt cttagctggc tatccattag tagatatcaa
    43141 agctaaactt tacgatggtt cataccatga tgtcgattca aatgaaactg ccttccgtgt
    43201 tgctgcttct atggcattac gtgcagcagc taagaaagct aatccagtaa tccttgaacc
    43261 aatcatggct gtagaagttg ttatccctga agattattta ggtgatgtta tgggtcacgt
    43321 aactgctcgt cgtggacgtg ttgaaggtat ggaagctcgc gctggcggcc aacaagttgt
    43381 tcgtgcgatg gttccacttg ctgaaatgtt tggttatgct acaactcttc gttctgctac
    43441 tcaaggtcgt ggtacattta caatgacatt tgaccactac gaagatgtac caaaatcagt
    43501 acaagaagaa atcattaaga aaaacggcgg aaaagctgaa taatttctta aaaccggata
    43561 gtcctgcaaa gagattatcc aaagagacta tatttttaat atagtttcgt gtaaaataat
    43621 tatcgatgat atgggcatgt ggtgtacctt gtgtacatca tatacctatc agacaaataa
    43681 aaaatatatt gtatttttag gaggacattt taaaatggca aaagaaaaat ttgaccgttc
    43741 taaaccacac gttaacattg gtactatcgg acacgttgac catggtaaaa ctacattaac
    43801 agctgcaatc acaactgtac tatctaagaa aaacggcggc caagctatgg cttacgatca
    43861 aatcgatggt gctccagaag aacgcgaacg cggaatcaca atctcaacag ctcacgttga
    43921 gtatgaaaca gatacacgcc actacgctca cgttgactgc ccaggacacg cggattacgt
    43981 taaaaacatg atcactggtg ctgctcaaat ggacggagct atcttggtag tttctgctgc
    44041 tgacggccca atgcctcaaa ctcgtgaaca catcctattg tctcgtcaag ttggtgttcc
    44101 ttacatcgtt gtattcttga acaaagtaga catggttgat gacgaagaat tactagaatt
    44161 agttgaaatg gaagttcgtg acctattaac agaatacgaa ttccctggtg acgatgttcc
    44221 tgtagttgct ggatcagctt tgaaagctct agaaggcgac gcttcatacg aagaaaaaat
    44281 tcttgaatta atggctgcag ttgacgaata catcccaact ccagaacgtg acaacgacaa
    44341 accattcatg atgccagttg aagacgtgtt ctcaattact ggacgtggta ctgttgctac
    44401 aggtcgtgtt gaacgtggac aagttcgcgt tggtgacgaa gttgaagttg ttggtattgc
    44461 tgaagaaact tcaaaaacaa cagttactgg tgttgaaatg ttccgtaaat tgttagacta
    44521 cgctgaagct ggagacaaca ttggtgcttt actacgtggt gttgcacgtg aagacatcca
    44581 acgtggacaa gttttagcta aaccaggtac aatcacacct catacaaaat tctctgcaga
    44641 agtatacgtg ttgacaaaag aagaaggtgg acgtcatact ccattcttca ctaactaccg
    44701 tccacaattc tacttccgta caactgacgt aacaggtgtt gttgaattac cagaaggaac
    44761 tgaaatggtt atgcctggcg acaacgtaac aatggaagtt gaattaatcc acccaatcgc
    44821 tatcgaaaac ggtactaaat tctcaatccg tgaaggcgga cgtacagttg gtgccggtgt
    44881 cgttacagaa atcaaagctt aattcactta agttttaaag taaagcaaca tttattcgga
    44941 cgtaatcgct cggaacgaag gtcttaggat ctttgttccg agctttttta tttattgcag
    45001 gatcaggaaa aaagacagga gtattataaa tagaagaaac acgaaataaa agagtcagta
    45061 ttttctaaat gaaactttat gaaaacaaaa tgttttttac aagaaaaagc cttgctttgt
    45121 gagtttatat atattataat gacaaaggtg cgtttacttt agtgaattgc acagacgtaa
    45181 tcagaatgat ttcgtcggct aagaaacgag aggttgcgac acgcccggac gctttgccac
    45241 gaacgagcgt gacggaaatt ttcgtggagc tatgtctact tttcaaaata ggcgaaggag
    45301 ggaacaagat ggcaaaacaa aaaattcgta tccgtttaaa agcgtatgaa caccgtattt
    45361 tagatcaatc agcggataaa atcgtggaaa ctgcaaaaag aactggagct agcgtgtctg
    45421 gtccaattcc attaccaact gaacgcagtc tttacacaat catccgtgcg actcataaat
    45481 acaaagattc acgcgaacaa ttcgaaatgc gtacacacaa acgtcttatc gacattgtga
    45541 acccaacacc aaaaactgtt gatgctttga tgaagctaga cttaccatct ggtgtaaaca
    45601 tcgaaatcaa attataaaac taaaacaaaa ataatggagg tgtactcatg accaaaggaa
    45661 tcttagggaa aaaagtggga atgacacaaa tcttcactga atctggtgaa ttaattccag
    45721 taactgttgt agaagctact ccaaacgtag tactacaagt gaaaacaatg gaaacggatg
    45781 gctacgaagc tattcaagtt ggttaccaag atatgcgtga agttttatca aacaaacctg
    45841 cgaaaggtca tgttgcaaaa gcaaacacgg ctcctaagcg cttcattcgt gaattcaaaa
    45901 atgttgagct aggagaatat gaagtaggaa aagaaattac agtagatgtt ttccaagcag
    45961 gagacattat tgatgtaaca ggtactacga aaggtaaagg attccaaggg gttatcaaac
    46021 gccacggaca aagccgcgga ccaatggctc acggttctcg ttaccatcgt cgtcctgggt
    46081 caatgggtcc agttgcacct aaccgtgtat ttaaaaacaa acgtcttgct ggccgtatgg
    46141 gtggcaaccg cgtaactatc caaaacttgg aagttgtacg tgtcgatgca gaaagaaatg
    46201 ttatcttgat caaaggtaat gttcctggag ctaaaaaatc tttaattact atcaaatcag
    46261 ctgtgaaagc taaataattg taggaagaaa ggaggaacta aggaatgccg aatgtagcat
    46321 tattcaaaca agatggaagc caaaacggtg aaatcacact taacgaagaa atcttcggaa
    46381 ttgaacctaa tgaaagtgtt gtttacgatg caatcgtaat gcaacgtgcg tcattaagac
    46441 aaggaacaca cgcggttaaa aaccgtagcg ctgttcgcgg cggcggacgt aaaccatggc
    46501 gtcaaaaagg aacaggtcgt gcacgtcaag gatctatccg ctcaccacaa tggcgtggag
    46561 gtggcgtagt ctttggacca acaccacgtt cttacagcta caaacttcct aaaaaagttc
    46621 gtcgtttagc aatgaaatct gtattgtcag aaaaagttgc tgaaaacaac ttggtagcaa
    46681 tcgaaggctt gaacttcgac gcaccaaaaa caaaagaatt caaacaagtt cttgctaact
    46741 tatctatcga ctctaaagta ttggttgttc tagaaaaagg taacgacttt gctgctttat
    46801 cagcacgtaa cttaccaaac gtttctgtag taacttctga taatgtgagt gtgctagacg
    46861 ttgtatcaaa tacaaaagtg ttagcaacac aaactgctct tactcaaatt gaggaggtgc
    46921 ttgcataatg aacttactag acgtaatcaa acgcccagtg atcactgaaa aatcaatgct
    46981 tgccatggat gacaagaaat acacttttga agtggacact cgcgcaaaca aaactttagt
    47041 aaaacaagcg gtagaagctg cttttgacgt taaagtcaaa aacgtgaaca tcgtgaacgt
    47101 acgtgcgaaa ttcaaacgta tgggcaaata tgcaggatat acaaaaaaac gtcgcaaagc
    47161 gatcgttaca ttgactgaag attcaaaaga aatccaatta ttcgaagctg ctgaataagc
    47221 actaatagat aactcattaa attaggaggg aaaaacgtgg cgattaaaaa gtacaaacct
    47281 acctcaaatg gtcgtcgtaa catgacaggt tctgattttg ctgaaatcac aacatcaaca
    47341 cctgaaaaat cattgttaca accattgaaa aaccatgctg gacgtaacaa caacggccgc
    47401 atcactgtac gtcatcaagg tggcggacac aaacgccaat atcgcgtgat cgacttcaaa
    47461 cgtaacaaag ataacgttgt tgcaactgtt caaacgatcg aatatgatcc aaaccgttca
    47521 gctaacatcg cgttagtaca ctatgaagat ggagtgaaag cttacatctt agcacctaaa
    47581 ggactagaag tgggtatgaa acttgtttca ggtccagaag cagatatcaa agtcggaaat
    47641 gctcttccat tagaaaacat tccagttggt actgttatcc acaacattga aatgaaacct
    47701 ggtaaaggtg gacaattgat ccgttctgct ggtacaagtg ctcaagtact tggtaaagaa
    47761 ggcaaatacg tattgatccg cttgaactct ggtgaagttc gtatgatctt agctgcatgc
    47821 cgtgctacaa tcggttctgt aggtaacgaa caacacgaat taatcaacat cggtaaagct
    47881 ggacgctctc gttggatgcg taaacgccca actgtacgtg gtagcgtaat gaaccctaat
    47941 gatcacccac acggtggtgg tgaaggtaaa gctcctatcg gacgtaaagc accagtttct
    48001 ccttggggtc aaccagctct tggttacaaa actcgtaaca aaaaagctaa atcagacaaa
    48061 cttattgttc gtcgtcgcaa aaataaataa ttactttgac catgtgtcgc acattttgag
    48121 aggaggttca ccatgggtcg tagtttaaag aaaggacctt ttgtcgatga gcatttaatg
    48181 aaaaaagttg aagctcaagc aggggttgaa aagaaaaaag ttatcaaaac ttggtcacgc
    48241 cgttcaacag ttttcccaag ttttgttgga tataccatcg cagtttatga tggacgtaaa
    48301 catgtaccag tttacatcca agaagacatg gtaggacaca aattaggtga atttgcacct
    48361 acaagaactt atcgtggaca tgctgctgac gataagaaaa cgaaacgcta atttgagggg
    48421 aggataaatc caaatggcag aacaaatcac atcagctaaa gcaactgcaa aaacagttcg
    48481 cacttcacct cgaaaagccc gtttagtaat tgaccttatc agaggtaaaa gtgtcgcaga
    48541 tgcaatttca atcttgaaat tcacaccaaa caaatctgct ggaatcattg aaaaagtatt
    48601 gatgtcagca gttgcgaatg cagaaaataa ctttgactta gatgttgaaa acttggtagt
    48661 aagcgaagct tttgttaacg aaggacctac aatgaaacgt ttccgtcctc gtgcaaaagg
    48721 atcagcttct ccaatcaaca aacgtacaag tcatatcacg gtagtcgtat cagaaaaata
    48781 aggagggata atcagtgggt caaaaagtac atccaattgg aatgcgtgta ggcatcatcc
    48841 gcgactggga tgctaaatgg tatgctgaaa aagagtatgc tgagttctta cacgaagatt
    48901 taagaatccg taaatttatt tcaactaaac ttgctgatgc tgctgtatca acagttgaaa
    48961 tcgaacgcgc aacaggtcgc gtaaacattt caattcacac agctaaacca ggtatggtta
    49021 ttggtaaagg cggttctgaa gtcgaaagcc taagaaaaga attaaacaaa ttaactggta
    49081 aaagaatcca tatcaatatc gtggaaatca aaaaaccaga tctagatgca aaattagtag
    49141 gtgaaggaat cgcacgtcaa ttagaaaacc gtgttgcttt ccgtcgcgct caaaaacaag
    49201 ccatccaacg ctcaatgcgt gctggcgctc aagggatcaa aactcaagta tctggtcgtc
    49261 taaacggagc agatatcgct cgttcagaag gatactcaga aggaactgtt cctcttcata
    49321 ctttacgtgc ggacattgat tacgcatggg aagaagcaga tacaacatac ggaaaactag
    49381 gagttaaagt gtggatctat cgtggagaaa ttcttccaac taaaaaaaac actgagaaag
    49441 gagggaaata atcatgttag tacctaaacg tgtaaaacac cgtcgtgaat tccgcggaaa
    49501 aatgcgcggg gaagctaaag gcggaaaaga agtagcattc ggtgaatacg gtttgcaagc
    49561 tgttgattca cattggatca caaaccgcca aatcgaagct gctcgtatcg caatgactcg
    49621 ttacatgaaa cgtggtggga aagtatggat taaaattttc cctcacaaat cttatactgc
    49681 caaagcaatt ggggtacgta tgggttctgg taaaggggca cctgaaggat gggttgcacc
    49741 agtaaaacgt ggtaaaatca tgtttgaaat cgcaggcgtt cctgaagaag tagctcgtga
    49801 agcgttacgt ctagcttctc acaaattacc aatgaaaact aagatcgtaa aacgtgagga
    49861 aatgggtggt gaatcgaatg aaggttaaag aaatcagaga attaaccact gccgaaatgc
    49921 ttgatcaaga aaaacaatta aaagaagaat tgtttaatct tagattccaa ttagcaacag
    49981 gtcaattaga aaacactgca cgtattaaag aagtacgtaa atcgattgca cgcatcaaaa
    50041 ctgtgttgcg tgaacaagct aagtaattat ggaaggaggc cattaagcgt atgactgaag
    50101 gaagaaatca acgcaaagtt tatcaaggtc gcgtggtttc agacaaaatg gataaaacaa
    50161 ttaccgttgc tgtcgaaaca aagaaaaacc accctatcta tggcaaacgc atgaactatt
    50221 ctaagaaata caaagtgcat gatgaaaaca acacagcaaa agttggcgac atcgtgagaa
    50281 ttatggaaac tcgtccatta tcagctacaa aacgtttccg tttgttggaa gtagtcgaag
    50341 aagcagttat tatctaataa cacgagattt tcctatatag attgaatgca aaatctgaaa
    50401 ggaggataca caacgtgatc caagcagaaa gtcgtttaaa agtcgctgat aactcaggcg
    50461 cacgtgaaat tttgacgatc aaagtccttg gtggatctgg tcgtaaaact gctaacatcg
    50521 gtgatgtgat cgttgctacg gttaaacaag caacgccagg tggggttgtc aaaaaaggtg
    50581 acgtcgttaa agccgttatc gttcgaacaa aatcaggagc tcgtcgtaca gacggttcat
    50641 atattaaatt tgatgaaaat gctgcagtga ttattcgtga tgataaaagc cctcgtggaa
    50701 cacgtatctt tgggccagtt gcacgtgaac tacgtgaaaa caacttcatg aagatcgttt
    50761 cactagcacc agaagtttta taatcttgag acacttatca aaggaggtgc gaaacagtta
    50821 tgtttgttaa aaaaggcgat aaagttaaag ttatcactgg aaaagacaaa aacaaagaag
    50881 gcgttgtact agcagcgttc ccgaaaaaag ataaagttat tgtcgaaggt gtaaatgtcg
    50941 ttaaaaaaca ccaaaaacct tctcaagctg ctcctcaagg tggaattgtt gagatggaag
    51001 cgccaattca tgtttctaac gtgatggtgg ttgactctac tggtgtagct ggccgagttg
    51061 gctacaaaga agtagacggc aaaaaagtcc gtgtttctaa aaaaaccggt gaagttttag
    51121 ataaataaaa gtttaaggaa ggagggtctt actgaatgaa ccgcctaaaa gaaaaatatc
    51181 ttaaagaagt aactccatca ttgatggaaa aatttaacta tagctctgtt atgcaaacac
    51241 ctaaagttga aaaaatcgtc atcaacatgg gtgttggtga tgcggtatca aacgctaaaa
    51301 acttagataa agcagttgaa gaattaactt tgatcactgg tcaaaaacca atgattacaa
    51361 aagctaaaaa atcaatcgct ggattccgtt tacgtgaagg aatgccaatt ggtgcaaaag
    51421 ttacattgcg cggagaaaga atgtacgaat tcttagacaa attggtttct gtttcactac
    51481 cacgtgtacg tgacttccat ggtgtaagta aaaaagcctt tgacggtcgt ggaaactata
    51541 ctttaggtat taaagaacaa ttgatcttcc cagaagtaga ttatgattta gtagataaag
    51601 tacgtggtat ggacatcgtt attgtaacaa cagcaaactc tgatgaagaa tctcgtgagt
    51661 tgttgacaca attaggcatg ccattccaaa aataattaaa ggaggcgaac tacgtggcta
    51721 aaaaatcaat gattgctaaa aacaaacgtc ctgcaaaatt ttcaacacaa gcttatactc
    51781 gttgcgaacg ttgcggacgt ccacattcag tttatcgtaa gttccatctt tgccgtattt
    51841 gcttccgcga acttgcctat aaaggtcaaa ttcccggcgt gaagaaagct agctggtaaa
    51901 aagtaaattc gcataagaag gaggtaaaag atcaatggtc atgacagatc caattgcaga
    51961 ttttctaact cgtatccgta acgcaaacat ggttaaacat gagtctttag aagtacctgc
    52021 atcaaaaatt aaacgtgaca tcgctgaaat cttgaaacgt gaaggtttcg ttcgtgatgt
    52081 tgaatacatc gaagatgaca aacaaggcgt gatccgtgtt ttcctaaaat ttggtaaaaa
    52141 cggcgaacgt gttatcacaa acttaaaacg tatctctaaa ccaggtttgc gtgcttatgt
    52201 caaagctgac gaagtaccaa aagtattgaa cggtttaggt atcgcaatca tttcgacttc
    52261 tgaaggtgtt gtcactgata aagaagctcg tgaaaaaaat atcggcggcg aagttatcgc
    52321 ttacgtatgg taatcaagta gaatctacaa ggaggtgtct ttaagtgagc cgtatcggaa
    52381 ataaagtcgt tgttatccct gaaggagtaa cagttactca agacggaaac aacgttacag
    52441 ttaaaggacc aaaaggtgaa ttgactcgta ctttttcagc agatatcaaa atgaatatcg
    52501 aaggaaacga agtaactttc actcgtccaa acgacagtaa agaaatgaaa acaattcatg
    52561 gaacaactcg tgcgaacttc aacaacatgg ttgtaggtgt cagcgaaggt ttccaaaaag
    52621 cgttagaact aatcggggtt gggtaccgtg cacaattaca aggatcaaaa cttgtattga
    52681 acgttggtta ctcacatcca gtagaaatca caccaccagc tggagtaact gttgaagtac
    52741 cagctaacac acaagtaatt gttaaaggtg cgaacaaaga agaagttggc gaattagctg
    52801 caaacattcg tggaactcgt cctccagaac cttataaagg taaaggtatt cgttatgttg
    52861 gcgaatatgt acgccgtaaa gaaggtaaaa ctggtaaata atcgtttaga aaaattgcat
    52921 agaagccagc agcaggaaaa aggcatttgg ctgaagttta ccttcaaaaa aatacatttt
    52981 tacttgtgcc gcagcttcta tttttcgaaa cgtatttact gcttgaaata gtagtacaat
    53041 aaaaataaag aggtgacaat tgtgattaca aaaccagata agaacaaaac acgtcaaaag
    53101 agacatcgtc gtgtacgtaa caatatctct ggtactgctg agcgcccacg cttgaacgtt
    53161 tttcgttcta acaaaaacat ctacgctcaa attattgatg acgtagcggg tgtaacgcta
    53221 gcaagtgcct ctaccttgga taaagaaatt tcaggtggaa caaaaacaga agcagcacaa
    53281 gctgtcggta aactagttgc tgaacgtgca gctgaaaaag gcattaaagt agtagtcttt
    53341 gaccgtggtg gataccttta ccatggccgt gtgcaagctt tagctgaagc tgctcgcgaa
    53401 aatggactag aattttagaa gaaggaggaa taccattcat ggtttatatc gatccaaaac
    53461 atttggaatt agaagaccgc gttgttgcaa ttaaccgtgt aacaaaagtt gttaaaggtg
    53521 gacgtcgtct acgttttgct gctttagttg ttgtcggtga caaaaacgga cacgtagggt
    53581 ttggtacagg taaagctcaa gaagttcctg aagcaatccg taaagcaatt gaagatgcga
    53641 agaaaaactt agttgaagta cctatggttg gttcaacaat cccacacgaa gtaatcggtg
    53701 cttttagtgg tggtagaatc ctaatgaaac ctgctgtaga aggttctggg gttgctgctg
    53761 gtggaccagt tcgtgccgta ttagaattag ctggggtagc agatatcact tctaaatctt
    53821 taggctcaaa tacaccaatc aacgttgttc gcgcaacagt tgaaggtttg aaacaattga
    53881 aacgtgcaga agaagttgca gaacttcgcg gcaaatcagt tgaagaatta atcggataag
    53941 gaggacaaca ataatggctg aattaaaagt tactttaaaa cgcagtatta tcggacgtcc
    54001 tcaaaaccaa cgcgatacag ttaaagcgtt aggtcttaca aagattaaca gttcagtggt
    54061 taagccttct aatgaagcaa ttaaaggcat gatcaatact gtttctcacc tagtggacgt
    54121 tgaagaaatt taatttagaa aaatcataac tagaacatta aggaggtgcc aaacctatga
    54181 aacttcatga attaaaacct gctgaaggtt cacgccaagt acgtaaccgt gttggtcgtg
    54241 gtacttcatc tggtaacgga aaaactgccg gacgcggaca aaaaggacaa aaagctcgtt
    54301 caggcggcgg tgtgcgttta ggatttgaag ggggacaaac accattgttc cgtcgtttac
    54361 caaaacgagg attcacaaac gtgaaccgta aagactatgc agtcattaat cttgatgtat
    54421 tgaaccgctt tgaagacgga gctgaagtaa ctcctgttgc tttagttgaa gctggaatcg
    54481 tgaaaaacga aaaagctgga atcaaagtat tagctaatgg ggaactaaac aagaaattaa
    54541 ctgtgaaagc agcaaaattc tctaaagcag ctcaagaagc aattgaagcg gctggtggat
    54601 caatcgaggt gatctaatgt ttagactatt aaaagatgct tttaaagtaa aagacattag
    54661 atcgaaaatc ctatttactg tatttgtgtt gtttgtattt cgcctaggtg cacatattac
    54721 tgtaccaggc gtaaatgctg cttcattgca aaacctttct tctttgccat ttttcaacat
    54781 gttgaacttg gtaagtggta gtgcgatgca aaacttttcc attttctcaa tgggggtttc
    54841 accatacatt actgcttcta tcgtcattca gcttcttcaa atggacatcg tgcctcgatt
    54901 tgttgaatgg tcgaaacaag gggaagttgg tcgtaaaaaa ctgaatcaag cgactcgata
    54961 tctgacatta gtattggcat ttatccaatc tgtcggtatc actgctggat tcaatcaata
    55021 cgctcaatta ggtttcgtga ataatcctaa cgtagcaact tacgtaacga tcggtttgat
    55081 tctaacagcc ggtacgatgt ttgttacttg gctaggagaa cagatcacag aaaaaggtat
    55141 cggaaatggc gtatcaatga tcatttttgc aggtatcatt tctagattgc ctgaaagtat
    55201 cagagaaatt tatgaagatt actttataaa tattgatcct tcagacatat ggaaatctgc
    55261 tatttttgtg gccattttac tagtagcggt cttgttgatc gtgacattcg taacattttt
    55321 ccaacaagct gaacgcaaga tcccgatcca atatacgaaa cgcgtagctg gcgcgcctac
    55381 aagcagctat ctgccgttga aagtaaatgc agctggagtt attccagtta tctttgctag
    55441 ttcgtttatt gctacgccaa atgctgtttt acaagcattg agcggtagat tcggttctga
    55501 aaactggtac aaagtgatga tggagatctt taactataat acagcacctg gtgctacgat
    55561 ttatacgatt ctgatcgttg ccttcacttt cttctacgcc tttgttcaag taaaccctga
    55621 gaaattagcg gaaaacttgc aaaagcaagg aagttatata ccaagcgtac gccctggtaa
    55681 ggggactgaa gagtatgtct caagattact gatgcgttta agtacagttg gtgcagtctt
    55741 ccttggttta gtggcattgc ttccaatcat tgctcaaatg gtttgggatc ttccacaatc
    55801 aatcggatta ggcggtacaa gcttactgat cgttatcggt gtagctttag aaactgcgaa
    55861 acagttagaa ggcttaatgc tgaaacgtaa atatgttgga ttcattgagt aagaaagcgt
    55921 gttgaggttt cccctcaaca cacgttctca cacatttatt aggagggaaa acaatgaacc
    55981 tcattttaat ggggctgcca ggcgcaggta aaggaacaca agctgaaaaa atcattgatg
    56041 cttatggtat tccgcacatc tcaacaggag atatgttccg cgcagcgatg caaaacgaaa
    56101 cagctcttgg cctggaagca aagtcttata tggataaagg tgcattagtt cctgatgaag
    56161 taacaaatgg aatcgtgaaa gagcgactag ctgaaccaga tacagagaaa ggcttcttat
    56221 tagatggctt tccacgtacg ctagatcaag caaaagctct ggacgcaatg ctaaaagatt
    56281 tgaataaaaa aattgatgct gtcatcgata tccatgttgg tgaagaaatc ttggtcgaac
    56341 gtctagccgg ccgatttatc tgcagcaatt gtggagcaac ttaccataaa attttcaacc
    56401 ctacaaaagt tgaagacaca tgtgatcgtt gcggtgggca tgaattctat caaagagaag
    56461 atgataaacc tgagacggtt aaaaatcgtc tggctatcaa catcaaaaat agtgaaccaa
    56521 tcttggctta ttataaagaa caaggtttgc taaacactat tgatggtgct cgtgaaatcg
    56581 atgctgtatt tgcagatgta caaaaaatca ttgaaaaata gcacgattgc ccgtagccga
    56641 cttgcattat gcagttactc ttgtcaagtt caataaatta tgatagaata tgtcagtccg
    56701 acttctagag aatcctctag atgatccatt ttgagaattt tgaggtggga actgcagttt
    56761 ccgccatttt atcgtgtgaa aatgcgaaac aagtacaagg aggtactgtg cgtggcaaaa
    56821 gaagatatga ttgaagtcga aggtacagtc gtcgaaactt tgccgaatgc aatgtttaaa
    56881 gttgaactag aaaacggaca ccaagttctt gctactgttt caggtaaaat tcgtatgcat
    56941 tacatccgta tcttacctgg tgacaaagta acggttgaat tgtctccata cgatcttaac
    57001 cgtggccgta ttacttatcg ctttaaataa ttgtactccg taaaactaca ggaggtatta
    57061 tcatgaaagt aagaccatca gtaaaaccaa tgtgcgaaca ttgtaaagta attcgtcgta
    57121 aaggacgcgt tatggtgatt tgcccagcaa atccaaaaca taaacaacgt caaggataat
    57181 tggaggtgct ataaatatgg ctcgtattgc aggagtagat attcctcgtg ataaacgtgt
    57241 agtagtttca cttacttata tctatggtat tggtaacact actgctaaaa agatcttagc
    57301 tgatgctggt gtatctgaag atgttcgcgt tcgtgaatta acgaatgaac aaacagatgc
    57361 tatccgtgca gaagtagata aattaaaagt tgaaggggat cttcgtcgtg aagtgaactt
    57421 gaacatcaaa cgtttgatgg aaatcggttc ttaccgtgga atccgtcatc gccgtggatt
    57481 gcctgttcgt ggacaaaaca cgaaaaacaa tgcacgtact cgtaaaggcc cagctcgcgc
    57541 tatcgctggc aagaaaaaat aattcttaag tgaaggaggt taaaacttca tggcagcaaa
    57601 aaaagtgaat cgtaaacgcc gtgtgaagaa gaatatagaa gcaggtattg cacatatcca
    57661 ttctacattc aataacacta tcatcatgat cactgatact cacggaaatg cattagcgtg
    57721 gtcatcagct ggttcattag gtttcaaagg aagcaaaaaa tcaactcctt ttgccgctca
    57781 aatggcagca gaaactgcta caaaagcagc aatggaacac ggattaaaga ctgttgaagt
    57841 aacagttaaa ggacctggtt ctggacgtga agcagcaatt cgttcattac aagctacagg
    57901 tttagaagtg actgcaattc gtgacgtgac tccagttcct cataatggtg cccgccctcc
    57961 aaaacgccgt cgtgtttaat gagtgccgct cattttgagt tttatcagta acgtcattga
    58021 acaagacact tttcgttttg aaaggggtaa agataagaat gattgagttc gaaaaaccaa
    58081 gaatcgcaaa aattgatgaa gaaaaagatt atggcaagtt catcgttgaa cctcttgaaa
    58141 gagggtatgg gactacttta gggaattccc tacgtcgtat tttattatct tctttgccag
    58201 gtgctgccat cactaatatt caaatcgatg gtgtactgca tgaattctct accatcaaag
    58261 gtgttagaga agacgtcact caaatcatct tgaacattaa aggcttagcg ctgaaaatgt
    58321 atggccaaga agaaaaaacc cttgaaatcg atattaccgg acctgctaca gtaactgctg
    58381 gcgatattat cgttgatagt gatgtagaaa ttcttaacaa agatatgtac atctgtagtg
    58441 tctctgaagg agctacgttc catgctcgct taacagtgaa acctggacgt ggttatgttc
    58501 aagcagatga aaataaaaaa gaagatatgc caattggcgt tcttccagtc gattcaatct
    58561 acacacctgt tcgtcgtgtg aactatcaag ttgagaacac acgtgttgga caccgtgaag
    58621 attttgataa attgacgatg gagatttgga cagatggttc aattgaaccg ttggaagcaa
    58681 tgagtttgtc tgcgaaaatc atgactgaac atttggatat ttttgtgaac ttaactgatg
    58741 aagcaaaaaa tgctgaaatc atggtcgaaa aagaagaaac acaaaaagaa aaaatgttgg
    58801 aaatgacgat cgaagagtta gacttgtctg ttcgctctta caattgtttg aaacgtgcag
    58861 gaatcaatac tgtacaagaa cttacaaata aatctgagcc tgaaatgatc aaagtccgta
    58921 acttaggacg taaatcatta gaagaagtta aagcaaaatt gcacgactta ggtttaggtt
    58981 tacgtaaaga agattaaaac cttttacgaa ggagggaaac caacgtgagt tatcgtaaac
    59041 taggacgcac atctagccaa cgtaaagcga tgttgcgtga tttaacaact gatttattaa
    59101 tcaacgaacg tattgtgact actgaagctc gtgcgaaaga agttcgctca actgcagaaa
    59161 aaatgatcac tttaggtaaa cgcggagatt tgcatgcacg tcgtcaagct gcggctttcg
    59221 tacgtaatga agttgccagc gtgcgtgaag aaaatgagga catcgtcatt gaatcagctt
    59281 tacaaaaact gttcaacgat attgcacctc gttacgcaga acgtcaaggc ggatacacac
    59341 gcattttgaa gacagaacca agacgcggtg atggtgcacc aatggttgtc ttagaacttg
    59401 tctaaaatca cactaataac atcactttat agatgattct tttagagtgt tatgatgttg
    59461 gaagatattt ttccgagtct agctcagcgc tgctcctcaa gcgaatatcg cttggggagt
    59521 aagcactcat cataaagtgt ttttttatac cttcaattac ctgtcatgac agatatgttt
    59581 gaaggcataa aaaaacattt taagcgagaa ataattgaaa attttgtctt tttttgatag
    59641 tgttagtagg aactttagga tgaagaagga gtaatcatgg agccaattat tgaattagaa
    59701 aagataaatt ataaatacca gccagatgat cttcgccccg cattgaaaga tgtctccttt
    59761 acaattgata aaggtgagtg gatcgctatt attggacaca atggttcagg aaaatcgaca
    59821 cttgccaaaa cgatcaatgg attgcttctg ccagaatcag ggatcgtgaa agtgggaaat
    59881 caaatattgg atgaagaaaa tatttggacg atccgacaga tggttggaat ggtttttcaa
    59941 aatccagaca atcagtttgt tggttcgaca gtagaagatg acgttgcttt tggtcttgaa
    60001 aatcaaggga ttcccagaga agaaatgcta gtgcgtgtga aagatgcact tgagaaagtt
    60061 agaatggctg agtttgcttc acgcgagcct gctcgtttat caggagggca aaaacaacgt
    60121 gttgccattg ccggcgtggt tgccttacga cctgatatca ttattttaga tgaagcaacc
    60181 agtatgctag atccagaagg tcgtgaagaa gtgatctcta cgatcaagaa gatcaaagaa
    60241 gaaagtcaat tgaccgttat atctatcact catgatattg atgaagcagc taatgccaat
    60301 cggatactag tgatgagaca aggcgaactt gtccgtgaag gtacaccaaa agaaattttt
    60361 tctgctggtc ctgaactgat cgacttaggt ctagatctac catttcctga aaaactgaag
    60421 agcgcactga aagaacgtgg ggttgatgtg cccagtgaat atatgacaga agaaaggatg
    60481 gtggattggt tatggacatc cgttttgaac aagtagactt cacttatcag ccgaatacac
    60541 catttgaaca aagagcctta tttgacatca atatgacgat caaagaaaac agttatactg
    60601 cattagtagg gcataccgga agcgggaaat caaccttact tcagcatttg aatgcgcttg
    60661 ttaagccaac aagcggtaca gtccatattg gagaacgaga tattcagccg gatacggata
    60721 ataagaattt aaagcccatc cgaaaaaaag ttggcatcgt ctttcagttt ccagaagcac
    60781 agctattcga agaaacggta gcaaaagaca ttgctttcgg tcctaaaaac tttggtgtca
    60841 gcgaagaaga agcactagtc ctagcaaaag aaacattaga acaagttggg ctggatgaaa
    60901 gctatttgga acgttcgcca tttgaacttt caggagggca aatgcgtaga gtagcaatcg
    60961 ctggtgtgct tgccatgagg ccggaagtac ttgtattgga tgaaccaacg gcaggacttg
    61021 atccccaggg tagaaaagaa atgatggaga tgttttggcg tcttcataag gaacagcaga
    61081 tcactattgt attagttacg catttaatgg atgatgtagc caattttgca gattatgtct
    61141 atgtgttgga aaagggacga atcgttaata gcggggagcc gcaagaggtc tttcaaaaca
    61201 ttgaatggct aaaagaaaaa caactaggcg tacctactgc caccgagttt gcagaagaat
    61261 taatggctaa agggatgaac tttgctacct tgcctttgac agctgaagaa ttagcagacg
    61321 ctatcgtcca ttatgctgga ggaaatgccc atgatgaata aattgatatt tggtcgttat
    61381 atgcctggag attccttgat ccatcgattg gatccccgag ctaaattatt agccagtttt
    61441 tattttatcg gaatcatttt tttagcaaat aattgggaaa cgtacctttt gttggcattt
    61501 ttcacattac tttctgtctt cttgtcaaaa gtagatttga aattttttat ccgaggcatt
    61561 cgcccattga tctggctaat cctcttcact gtagctttgc aggtcttgtt tacaagtggc
    61621 ggagaaactt attggagttg gggtgttttc catatcactg aatttggtgt gatgaacggc
    61681 ctctttattt tctgtcgatt cgtgttgatc atttttatgt cgactctact cacgcttact
    61741 acaccgcctt tggaattatc ggatgcgatt gagtacttgc ttcgtccatt gaaagccgta
    61801 cggttcccag tccacgaaat ttcattgatg ctgtcgattg ctcttcgttt tgtgcctaca
    61861 ttgatggacg aaacagaaaa gatcatgaac gctcagcgcg ctcgcggtgt tgattttggt
    61921 gaaggaaacc tagttcagaa aatgaaagca gtcattcctt tgctgattcc tttatttgtc
    61981 agcagcttca accgtgcgga agatcttgcg actgctatgg aagcaagagg ctacaaaggt
    62041 ggggaaggaa gaacgaaata tcgtgtattg cattggcata atagagacac gatggttatc
    62101 attgcttttg tattattaac tgtgctactg atctttttga gaggataaac gttcagtggg
    62161 ccgctatcta ttcttttctt gctgatctgt ttgcaagaaa ggatgcgagc agtgtatgac
    62221 aagaaatatt agggtctgtg gcagactaag gtcacaggcc tctttctttt atctgaaaag
    62281 aaagaacgaa aaaattttat aaaaaaatca ttattccaga taacctttta ggaacaaagg
    62341 agagaaaaac atggtacgtt acaaagcaat cattgcatac gacggaacaa attttaatgg
    62401 attccaaaaa cagccaaatg ggcgtactgt tcaagaagaa gtagaaaaaa cattacaaaa
    62461 aatggcaaat ggaaaagaaa tcacggtctt tggttcggga aggacagatg ccggagtaca
    62521 tgcgattggg caagtaatcc attttgatta tccagaggag cgtccgttag aacgaatgcg
    62581 tttcgcgcta gatacccagt caccagagga tattgctgta agacaagtag aaattgtttc
    62641 agaagacttc cacgcaagat atttggtcaa agaaaagacg tatcaatttc gagtggatat
    62701 agggaaacca cgcagtcctt ttcgacgcca ttatgcaagt tattttcctt accctcttga
    62761 tttggaaaaa attcagcggg cgcttcctga tttattaggg actcacgatt tcacctcttt
    62821 ttgtgcatca ggaagctcga tagaggataa agtacgtacg atctacgagg ctaagatgga
    62881 ggtaaatgaa acaaaagacg aattgttgtt tacatttagg ggaaatggct tcttgtataa
    62941 gatgatacgg atcttagtag gaacgctttt gaaaattggc aatggccgat tgcctgaaga
    63001 tagtatccca gatattattg cgaaaaaaga tcgtaatgca gcaggaccta cagcacatcc
    63061 tgaaggactt tatttgtatg aagtgaaata tgaataagag gttgtgacag aagtggtcag
    63121 cttcaagaaa taagaaggaa tttacgaaaa ttacttctca aaattttgca aaatttcggc
    63181 ttattttcga aggagctact tctggaacac cgtgaatcag aggttgtgaa aaagctgccc
    63241 tgcatcaagt aataagaaca accaaacaaa aatagctcgt catatttttc gtttggttgg
    63301 gcttattacc gcagatgcaa gcttttgaac accgtttaag gaagaggttg tgaaatcagc
    63361 gttttgacct gagtattaga gaaacaaacg gaaaaatagt tcctcatatt ttgccgtttg
    63421 ttgagctaat accgaaggtc agctgattga acaccgttta agaaagaggt cgtgagcctg
    63481 tcatttaact ctgagtcaca agtaacaatt tcaaaaaaca gcttctcatc tttgatgaat
    63541 atcgtgactt gtggacgagg cgttgataag tgaatcatct ttttgttacc tattttttct
    63601 gtaaccaaaa aacgatggaa cgttgttttg attgccctta atgaggacag tcggaacagg
    63661 tttgtcattt ttatatttaa atggcacaaa tttttctaat tatttgtcat ttagcgctga
    63721 aaatttttgc tatttatcta aaaaagtgat aactacttaa gatgaagcag aatatttacg
    63781 ccatacggca tacaaccgcg aaaaatataa aaaaaagaaa acgattgaac gcgtttttgc
    63841 agtcgcaaag gaaaagcatg gaatgcgcta catcaagtat cgagacttgg aaaacaatca
    63901 ggtgtatacg ctgattgttt ttgctgcaat gaatctgaaa aagttgtcca cttggcagtt
    63961 ggaacatatg tcttcatatc ttttattata caaaaatagc aaaagcacca gtctacactc
    64021 ttagtaaaga ggaaactgat ccttttgtct acattcttaa agtacttaaa ctaagtactt
    64081 tattttactc tttaggattg atacagtagc atctatccct ttattaataa tcttttattt
    64141 ttttaaataa agatgttgtc tccatcttca ggcactaaaa ctttttcgga aattcctttt
    64201 tctttattga aagactttaa ttcttctctt gacagtcccc aatggtttac agcttccata
    64261 tgaacggcaa taattgtgga atctggtatt gctttatgca attcatataa atcgtctttc
    64321 cccataataa gagattctcc aactaaaaaa tgattatctc cagcatttgc tactatgatt
    64381 tctggattat actgatcaat agtttgttta acagcttcat accaaactgt atctcctgta
    64441 aagtatagtg tcttctcagt cgaatgtttg aaaacaatac cgcaaacatt acctacataa
    64501 ttcaagattt ctcctctgcc atgtttgcct tttgttttaa ccaattgtat agattcaaaa
    64561 actgtgtctt ctcgtagtac ctccacattt ttaaaaccat atagtcgaat ttcattcgca
    64621 tcattttcat cttgcacaaa taattttatt tctttaggta ggacctcttt cgctatatcg
    64681 tcccaatgat ctagatgtaa atgtgttaca ataacagcat caataccgtt gataatatct
    64741 tcgactggca ttggcaaatc aactagagga ttcatttgat cttttcttgg tgatggaaaa
    64801 ggacctttcg aaataaatgg tggaagtgtt cctttttccg ctaacattgg atcaattaaa
    64861 aattttttac ctccatagtc taagatagct gttgcattac gaatgtgatg tatattcata
    64921 aacgttgtct cctttttgtt gatatgaaat atttttagta taattcaatt ccatacaata
    64981 aataaaccga acaaaaaaag tcttttacta tttttactta atttatgaaa ggttgtttac
    65041 catgttagac caaacagata taaatatcat tgaggaacta tcaaaaaata gtcgaatcac
    65101 aatgaaagaa cttggagaaa aagtacattt gactggaccc gctgtctcgg cgagagtgac
    65161 aaaactagag gaaagtggag ttattgaaaa ttatacagta aaattaaata tggaaaagct
    65221 agggttttcg attcacgctt ttttaattat aattacgcaa aatttaaatc ataaacccta
    65281 tttatcattt attaaaaatc atgaaaaatt cttgattaga aattataaga ttagtggagg
    65341 gggctgttat cttttggaat gtagatttac ttcaaaaaaa tcaatgaaca gctttttgga
    65401 acagcttaat gaatatgcga attataaatt atctattgtt atagattaat aataaaacta
    65461 gcagatggta aaaatactaa tatgcgagac acacattcaa ccataactat ataacttatc
    65521 aatttaaaac taaactgatg gaaacaagta aggcaaaaac atttatattt tgccctactt
    65581 atttttttaa ttaaattcat tgatgattca tatttagaaa attctatgaa ggccaaatga
    65641 gtatcctgtc acttttttag ataaatagca aaaattttca gcgttaaatg acaaataatt
    65701 agaaatattt gtgccattta aatataaaaa tgacaccaag tatatcatga acgcacaaaa
    65761 agaccaacag ggtataccct gttggtctaa ataa
//
LOCUS       DADQDV010000006        64781 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.006, whole genome shotgun sequence.
ACCESSION   DADQDV010000006 DADQDV010000000
VERSION     DADQDV010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 64781)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64781)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64781
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.006"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            160..678
                     /locus_tag="J8S10_000399"
     CDS             160..678
                     /locus_tag="J8S10_000399"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAZ9629013.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            806..1489
                     /locus_tag="J8S10_000400"
     CDS             806..1489
                     /locus_tag="J8S10_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HAZ9629014.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            1798..1871
                     /locus_tag="J8S10_000401"
     tRNA            1798..1871
                     /locus_tag="J8S10_000401"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1832..1834,aa:Arg,seq:tct)
     gene            2030..2389
                     /locus_tag="J8S10_000402"
     CDS             2030..2389
                     /locus_tag="J8S10_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HAZ9629015.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            2512..4143
                     /locus_tag="J8S10_000403"
     CDS             2512..4143
                     /locus_tag="J8S10_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HAZ9629016.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(4205..4846)
                     /locus_tag="J8S10_000404"
     CDS             complement(4205..4846)
                     /locus_tag="J8S10_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HAZ9629017.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     gene            5128..5436
                     /gene="rplU"
                     /locus_tag="J8S10_000405"
     CDS             5128..5436
                     /gene="rplU"
                     /locus_tag="J8S10_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HAZ9629018.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            5463..5807
                     /locus_tag="J8S10_000406"
     CDS             5463..5807
                     /locus_tag="J8S10_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HAZ9629019.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            5820..6113
                     /gene="rpmA"
                     /locus_tag="J8S10_000407"
     CDS             5820..6113
                     /gene="rpmA"
                     /locus_tag="J8S10_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HAZ9629020.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            6520..9354
                     /locus_tag="J8S10_000408"
     CDS             6520..9354
                     /locus_tag="J8S10_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAZ9629021.1"
                     /translation="MAKRIDRIYMYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNS
                     SKDLNQLVREGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDT
                     KDIFAKIIGANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAH
                     HVIDEETELIVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLD
                     EIHRLPPEGQEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRI
                     PINIKLPAFEKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQL
                     KSNIQLVCARGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKIT
                     VAPNDTIMKIQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFY
                     KDHGFSFNADSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKK
                     INLGEERHTNDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLR
                     ANQASGRIGVVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNV
                     QEVDEGSGVILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDL
                     DMLHESLKNFRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNK
                     RQETELEVLALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVI
                     LDQLLMESELEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTT
                     GIGDEEYGFKINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLED
                     QIKVKVPIEEMYYLLRLVHNQLDKKEYTVP"
     gene            9545..10036
                     /locus_tag="J8S10_000409"
     CDS             9545..10036
                     /locus_tag="J8S10_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIB"
                     /protein_id="HAZ9629022.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            10139..11128
                     /gene="manX"
                     /locus_tag="J8S10_000410"
     CDS             10139..11128
                     /gene="manX"
                     /locus_tag="J8S10_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HAZ9629023.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            11161..11964
                     /locus_tag="J8S10_000411"
     CDS             11161..11964
                     /locus_tag="J8S10_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HAZ9629024.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            11985..12899
                     /locus_tag="J8S10_000412"
     CDS             11985..12899
                     /locus_tag="J8S10_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HAZ9629025.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            12982..13356
                     /locus_tag="J8S10_000413"
     CDS             12982..13356
                     /locus_tag="J8S10_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HAZ9629026.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGNNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            13495..13740
                     /locus_tag="J8S10_000414"
     CDS             13495..13740
                     /locus_tag="J8S10_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAZ9629027.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            13912..14976
                     /locus_tag="J8S10_000415"
     CDS             13912..14976
                     /locus_tag="J8S10_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HAZ9629028.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            15222..15647
                     /locus_tag="J8S10_000416"
     CDS             15222..15647
                     /locus_tag="J8S10_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAZ9629029.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            15640..16089
                     /gene="nusB"
                     /locus_tag="J8S10_000417"
     CDS             15640..16089
                     /gene="nusB"
                     /locus_tag="J8S10_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HAZ9629030.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            16186..17040
                     /locus_tag="J8S10_000418"
     CDS             16186..17040
                     /locus_tag="J8S10_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HAZ9629031.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            17041..18378
                     /locus_tag="J8S10_000419"
     CDS             17041..18378
                     /locus_tag="J8S10_000419"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HAZ9629032.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            18383..18607
                     /locus_tag="J8S10_000420"
     CDS             18383..18607
                     /locus_tag="J8S10_000420"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HAZ9629033.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            18609..19499
                     /locus_tag="J8S10_000421"
     CDS             18609..19499
                     /locus_tag="J8S10_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HAZ9629034.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            19508..20326
                     /locus_tag="J8S10_000422"
     CDS             19508..20326
                     /locus_tag="J8S10_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HAZ9629035.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            20433..20882
                     /locus_tag="J8S10_000423"
     CDS             20433..20882
                     /locus_tag="J8S10_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HAZ9629036.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            20900..22582
                     /gene="recN"
                     /locus_tag="J8S10_000424"
     CDS             20900..22582
                     /gene="recN"
                     /locus_tag="J8S10_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HAZ9629037.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(22637..22753)
                     /locus_tag="J8S10_000425"
     CDS             complement(22637..22753)
                     /locus_tag="J8S10_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HAZ9629038.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(22826..23782)
                     /locus_tag="J8S10_000426"
     CDS             complement(22826..23782)
                     /locus_tag="J8S10_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HAZ9629039.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            23953..24321
                     /locus_tag="J8S10_000427"
     CDS             23953..24321
                     /locus_tag="J8S10_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HAZ9629040.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            24491..24922
                     /gene="mraZ"
                     /locus_tag="J8S10_000428"
     CDS             24491..24922
                     /gene="mraZ"
                     /locus_tag="J8S10_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HAZ9629041.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            24943..25902
                     /gene="rsmH"
                     /locus_tag="J8S10_000429"
     CDS             24943..25902
                     /gene="rsmH"
                     /locus_tag="J8S10_000429"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HAZ9629042.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            25907..26308
                     /gene="ftsL"
                     /locus_tag="J8S10_000430"
     CDS             25907..26308
                     /gene="ftsL"
                     /locus_tag="J8S10_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HAZ9629043.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            26309..28501
                     /locus_tag="J8S10_000431"
     CDS             26309..28501
                     /locus_tag="J8S10_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HAZ9629044.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKNGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            28527..29489
                     /locus_tag="J8S10_000432"
     CDS             28527..29489
                     /locus_tag="J8S10_000432"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HAZ9629045.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            29503..30864
                     /locus_tag="J8S10_000433"
     CDS             29503..30864
                     /locus_tag="J8S10_000433"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HAZ9629046.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            30890..31978
                     /gene="murG"
                     /locus_tag="J8S10_000434"
     CDS             30890..31978
                     /gene="murG"
                     /locus_tag="J8S10_000434"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HAZ9629047.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            31993..33213
                     /locus_tag="J8S10_000435"
     CDS             31993..33213
                     /locus_tag="J8S10_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HAZ9629048.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            33369..34694
                     /gene="ftsA"
                     /locus_tag="J8S10_000436"
     CDS             33369..34694
                     /gene="ftsA"
                     /locus_tag="J8S10_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HAZ9629049.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            34717..35958
                     /gene="ftsZ"
                     /locus_tag="J8S10_000437"
     CDS             34717..35958
                     /gene="ftsZ"
                     /locus_tag="J8S10_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HAZ9629050.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            35975..36652
                     /locus_tag="J8S10_000438"
     CDS             35975..36652
                     /locus_tag="J8S10_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HAZ9629051.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            36666..37265
                     /locus_tag="J8S10_000439"
     CDS             36666..37265
                     /locus_tag="J8S10_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HAZ9629052.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            37280..37567
                     /locus_tag="J8S10_000440"
     CDS             37280..37567
                     /locus_tag="J8S10_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HAZ9629053.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            37616..38398
                     /locus_tag="J8S10_000441"
     CDS             37616..38398
                     /locus_tag="J8S10_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HAZ9629054.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            38419..39126
                     /locus_tag="J8S10_000442"
     CDS             38419..39126
                     /locus_tag="J8S10_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HAZ9629055.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            39388..42186
                     /gene="ileS"
                     /locus_tag="J8S10_000443"
     CDS             39388..42186
                     /gene="ileS"
                     /locus_tag="J8S10_000443"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HAZ9629056.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(42235..43761)
                     /locus_tag="J8S10_000444"
     CDS             complement(42235..43761)
                     /locus_tag="J8S10_000444"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HAZ9629057.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(43776..44423)
                     /locus_tag="J8S10_000445"
     CDS             complement(43776..44423)
                     /locus_tag="J8S10_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HAZ9629058.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(44607..44936)
                     /locus_tag="J8S10_000446"
     CDS             complement(44607..44936)
                     /locus_tag="J8S10_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HAZ9629059.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            45113..45841
                     /gene="sfsA"
                     /locus_tag="J8S10_000447"
     CDS             45113..45841
                     /gene="sfsA"
                     /locus_tag="J8S10_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HAZ9629060.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            45857..46870
                     /locus_tag="J8S10_000448"
     CDS             45857..46870
                     /locus_tag="J8S10_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAZ9629061.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            46870..48147
                     /locus_tag="J8S10_000449"
     CDS             46870..48147
                     /locus_tag="J8S10_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAZ9629062.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            48210..50912
                     /locus_tag="J8S10_000450"
     CDS             48210..50912
                     /locus_tag="J8S10_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAZ9629063.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            51064..51381
                     /locus_tag="J8S10_000451"
     CDS             51064..51381
                     /locus_tag="J8S10_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAZ9629064.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            51411..51731
                     /locus_tag="J8S10_000452"
     CDS             51411..51731
                     /locus_tag="J8S10_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAZ9629065.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            51839..53299
                     /locus_tag="J8S10_000453"
     CDS             51839..53299
                     /locus_tag="J8S10_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAZ9629066.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGILPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGSNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            53367..53588
                     /locus_tag="J8S10_000454"
     CDS             53367..53588
                     /locus_tag="J8S10_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629067.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            53619..53801
                     /locus_tag="J8S10_000455"
     CDS             53619..53801
                     /locus_tag="J8S10_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HAZ9629068.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            53801..54214
                     /locus_tag="J8S10_000456"
     CDS             53801..54214
                     /locus_tag="J8S10_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HAZ9629069.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            54337..55518
                     /locus_tag="J8S10_000457"
     CDS             54337..55518
                     /locus_tag="J8S10_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAZ9629070.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            55907..55980
                     /locus_tag="J8S10_000458"
     tRNA            55907..55980
                     /locus_tag="J8S10_000458"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:55941..55943,aa:Arg,seq:cct)
     gene            complement(56049..57188)
                     /locus_tag="J8S10_000459"
     CDS             complement(56049..57188)
                     /locus_tag="J8S10_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAZ9629071.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            complement(57487..58122)
                     /locus_tag="J8S10_000460"
     CDS             complement(57487..58122)
                     /locus_tag="J8S10_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629072.1"
                     /translation="MDNSNEKLTKKEYLELIVEGGIGAIPYIGGVVQSLYFGSKNEKR
                     FKRIEKFYKNLNESLENIRDQIPEDVFNLENKDQLIGIFEGINDEVEKSKAQNKIDMY
                     KNLYKNCLLRINNASWDNEEYYLLVLNQLTSIEIQLLACLMSRGNENFTGNISMSGYS
                     QELIDGSLNRLSDFGLLEKTISSIVLGDVGKQNMGYKISHLGIQFINSTLT"
     gene            complement(58235..58870)
                     /locus_tag="J8S10_000461"
     CDS             complement(58235..58870)
                     /locus_tag="J8S10_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3221 domain-containing protein"
                     /protein_id="HAZ9629073.1"
                     /translation="MDGIFGFTGIVLFIIGLIMLIVRFIKKTNKKTPMILLIIGIIFT
                     TVGFSLSSSNEANDNNKQESSSSDTQTTTSNSSNKSLTQFEEFLETNNHDWGAFLDSY
                     YSITPATEQNTAFTKYISGKTYTFEGTVIESMTTRIAIIADKEYDDKSWNDISATPKV
                     SYVIFAKDLNNADTFTKGDKVTFTGEISSRGSNIEKSYAQWDMINSKVSKK"
     gene            complement(58904..59365)
                     /locus_tag="J8S10_000462"
     CDS             complement(58904..59365)
                     /locus_tag="J8S10_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4429 domain-containing protein"
                     /protein_id="HAZ9629074.1"
                     /translation="MEKEILIKSPGKTLIKVTDDSISIIRKGFINLVNQGIKGEKTIP
                     FKNISAVQLKKPGMSNGYIQFTLLGGNESRGGILAATKDENTVMFTKKYWNEMENLKK
                     YIEKQQSILDNNSKETQISSADEIKKYKELLDEGIINQEEFDFKKKELLGL"
     gene            complement(59495..59926)
                     /locus_tag="J8S10_000463"
     CDS             complement(59495..59926)
                     /locus_tag="J8S10_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HAZ9629075.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            complement(59944..60264)
                     /locus_tag="J8S10_000464"
     CDS             complement(59944..60264)
                     /locus_tag="J8S10_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAZ9629076.1"
                     /translation="MNTYEIIKDLAKRKKISIRQLEINFGYSNGYLAKWKNNTPNSDE
                     LSRIADYFDVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            60563..61339
                     /locus_tag="J8S10_000465"
     CDS             60563..61339
                     /locus_tag="J8S10_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HAZ9629077.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKEGYYPQMDLEEIG"
     gene            61354..61557
                     /locus_tag="J8S10_000466"
     CDS             61354..61557
                     /locus_tag="J8S10_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAZ9629078.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            61573..61911
                     /locus_tag="J8S10_000467"
     CDS             61573..61911
                     /locus_tag="J8S10_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HAZ9629079.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            61898..62077
                     /locus_tag="J8S10_000468"
     CDS             61898..62077
                     /locus_tag="J8S10_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629080.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(62120..62590)
                     /locus_tag="J8S10_000469"
     CDS             complement(62120..62590)
                     /locus_tag="J8S10_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629081.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            62677..63375
                     /locus_tag="J8S10_000470"
     CDS             62677..63375
                     /locus_tag="J8S10_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HAZ9629082.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            63553..63894
                     /locus_tag="J8S10_000471"
     CDS             63553..63894
                     /locus_tag="J8S10_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629083.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            63887..64558
                     /locus_tag="J8S10_000472"
     CDS             63887..64558
                     /locus_tag="J8S10_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HAZ9629084.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            64564..>64781
                     /locus_tag="J8S10_000473"
     CDS             64564..>64781
                     /locus_tag="J8S10_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629085.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDI"
BASE COUNT        21467 a        10835 c        13574 g        18905 t
ORIGIN      
        1 taacgtcaat tatttataat aaaaaatgag ataaagatga ggaaatagaa ttagaaacat
       61 ataattatta aagggaaaca tttttacagc tataatttga aaaaatttat cgttattata
      121 tgattaagaa ggattgaata aagaaagaag ttgaaaacga tacctgatta caaaaaaata
      181 acttttataa gttctataac gttgattata tttttaattc ttattcttct cgtcgtcttg
      241 gttccccgaa tttttggttt gactccttat attattgagg acaaagaaat gagtccatat
      301 tatgcacaag gaaatctgat atatgtacga ccgaaaaata caaatgagat tttagtcgga
      361 gatattatta catattatga aaattcagga aaaaaaatct cgacgcgtcg cgtaatagcc
      421 gttgaaaaca accacgaaga tttttataca aaagctgata caaagactta tattgagcct
      481 ggagtagtaa aaaagagaaa tattatcggt agtcccatct ttcagattcc atatattgga
      541 ctagtccttt caaaaacggc atttgcatgg attcaggggt tattctttac gattgctttt
      601 tgcctaacag gaatcacagc atggaatacc tttgtagagt tgaaaaagaa gcggagacga
      661 acacagaaat ttttgtaaga atgttaaaaa cataaatgta ttccagagat ccaacgactc
      721 ttctgaacat gaaacacgag aaaacactca tgcagcttgt agatttagtc agttgttcgt
      781 ataatgtgtg aagaggagga gtagtatgcg caatgaaatg atgcatcgtc ctgtagtcaa
      841 agaagaacta ttggatttta tgcgtaccca gcaaaaaaaa ttaccgggtg agctaggcaa
      901 actggaagaa gaagctcatg tagcagaagt accagttatt ccccatgaaa cagttgtatt
      961 tttgaaattt ttacttggac agcttcagcc tgaacgaatc ttggagatcg gagcagctat
     1021 cggtttttca tcaagtgtca tggccacgac aatcggagaa aacgctcatg ttacgacaat
     1081 tgatcgtttc gatgtcatga tcgagaaagc taaaaaaaac tatgaacgtc taggactgac
     1141 agataaagtg actttgcttg aaggtcaagc agcagatatc ttgccggagt tgtctggtcc
     1201 gtatgacttt atttttatgg atagtgcaaa atcaaaatat attgaatttt tacctgaatg
     1261 cttacgtttg ttaagaaaag gtggcgtttt gatggtagat gacatcttcc aaggaggaac
     1321 gatcttgctc ccagatgaag agattccccg tggcaaacga gctatccatc gtaaattaaa
     1381 tgaatttctt cgtgttgtga tggatcatcc cgatttgaca tcgacaatct tgccattagg
     1441 tgatggtgtg atcttaatga caaaggaatc agaaacaatc gagttgtgat acatgattat
     1501 ggcagcctgt agataatcga ttgaatcgag ggctcaattc gaacttgatg taaaagtttc
     1561 tatatttgta agtcaattaa aggatacagg aaatctaaat aaacaggagt agcatgaagt
     1621 caatgtagct cctgttttca attgataacc ttagaacagc tgaaggagaa tgtctcgttt
     1681 taaaagattg atttagtagt tgggccaaaa taattcatta tttgctaatt aaataactat
     1741 ttcgtattga cagaagcaat ttaattatct ataattattg atgttccgct gattcttgtc
     1801 atagtagctc agctggatag agcatccgcc ttctaagcgg acggtcgggg gttcgaatcc
     1861 ctcctgtgac gctaaaaaac cgttagaaac tgaggtttct aacggttttt ctttgttttt
     1921 tgtgccaata ttgtttgttt tcaaaggcaa ataaaataaa aaaacatcct tatcgagtac
     1981 aattataagg agcaaaaaaa taaaactcat cagaaaagag gaagaagata tgacgatact
     2041 atctagaatt ttagtgactc tagttgcaat tgaatttttt tatatcatgt atatcgaaac
     2101 ggtgagaact gattctgaca cgacaagtag ggtttttaaa atgagtaaag aagagttaag
     2161 cagaaaatct gttcaaacat tgtttaagaa ccaaggagtg tacaatggac tattaggagt
     2221 gggactactt tatggagctt atctttcttc cgcatctaaa gaaatcacaa gtatgctatt
     2281 aatatctatt ttttttgttg cattatatgg cagtttgact agcgatcgtt ggattttact
     2341 caaacaaggt gggctagctc tgttggcatt gctttctatt ttcttataaa tatagaaaaa
     2401 ataagaattt atctaacagg aaactttgtg aaaaatatta ctttatctca tgaaatatga
     2461 tattctaatg aatggtattt tagaaaattt catgaaaaag gagttagata ggtgttcaaa
     2521 aattatgttt cctcactaaa aaaagaattt tcaggttatg atctttcaag atttcagaaa
     2581 gatcttttgg ctgggatcac agtagctgct gtagcattgc ctttagcctt ggcttttggg
     2641 gtatcaagcg gagctgatgc ggccgcaggt ttgattacgg ctatcattgc cggtatcgtt
     2701 attggcggtt tatcaggcgg tttttatcaa atatcaggtc cgacaggtgc gatggcagct
     2761 atcttgatgt ctattgcggc aacaaaggga atgcaaggtg tattgcttgc tactttttta
     2821 gcgggtctat ttttacttgc agcaggactt ttccgattag gaacactgac ttcttttatc
     2881 ccagcacccg taattacggg gtttacttca ggtattgcta tcattattgc attaggtcag
     2941 atcgataatt tatttggtgt tcactcggaa ggtacaaacg ttattgaaaa actaagtagt
     3001 tatcaaacga taggatttcc gataaacaca gcctctttga tcatgggagg gctagtcatt
     3061 ttagggatgt ttatctatcc aaaaaaatgg gcgaaacgaa tgcctagttc gctgctggct
     3121 atcattttgg caacagcagt tatgctattg ttccatttac cagtagcaac tgtgggtaag
     3181 attccacaaa cattgatcag tagtaatcgt ttgaatatgg gagattttag cttttctgcc
     3241 ttgcaacaag tggcagttcc agctattagc attgctttat taggaatgat tgaaagcttg
     3301 ctatgtggtg cttcggctgg ccgaatggca aataagccct tagatagcaa tcaagaatta
     3361 atggcgcaag gaattggaaa tctgttgctt cctttctttg gcgggattcc tgctactgcg
     3421 gccatcgccc gtacaagcgt ggccatcaaa tctggtgcac aaactagatt agctggtatg
     3481 atacatgcag ttgtcttact gctctccatg cttgtttttg cgccagtgat gtcacagatt
     3541 ccaatgccag cacttgcagg tgttttgatt gtgacggctt ggcgtatgaa tgaatgggaa
     3601 acgatcaagg agctatttac taataaatat tggtcagcag ttctattgtt tatccttacg
     3661 atgatttgta cagttatctt tgatttaagt attgctatcg tgatcggggt gatcggcggc
     3721 tgtgtatttt ttgttgtcaa aagcgctgct atcacgattt cattagaaac gatcgattgg
     3781 caaagaatgg ggctgccaga aacggaaaag ctgaataact ggacagtagt gtatattagt
     3841 ggtccactgt tttttatgtc ttcagaaaaa ctcaaaaata aattggaaga actaaatcat
     3901 cacgatggtg tcattttctc catgcgaggc gtaccaagta ttgatttgac ggcacgtgca
     3961 gtttttgatg aatttcaaga aaaagcagag caaagaggac aaacgattat ctatacttcc
     4021 ttgcagccag aagtagaaaa acaactttct cacttgtggg aacatacatt cacgcatcaa
     4081 catcaaacag ttgctcatgc gttgacagct ttacatgcga aatatactgc aattagccat
     4141 taaaacaatg aaaaagaaca gacaagactg taaactgaag attttatggt cttgtctgtt
     4201 ctttttaata ttgctgtaaa agtgaagcta gtacttgcca gtcttgatgg ataacaggta
     4261 caagggagcg attgtagaaa atagctgctg gatgaaaaag tggaagaatt cgatagtttt
     4321 tttctgacca ttcgtaggca tccttttgtt ctgttaattg taagacaggc cctgtataga
     4381 gttgaccatg atttttggta accgtatatt ctttgccaag taaacgttga agaccaatgt
     4441 ttccaagtgt cgcaattaat tttggctgga ccttcatcag ttcgtaatcc aatattggtg
     4501 catgcgcaaa tacttcggaa cgagtaggtg tccgatttgg ataaacagtt tctgactgtt
     4561 gtgtccgttt attgatccga tgagtcacgc gatacgggcg gctccttaca gcactggtga
     4621 tatacacctc ttctcgtgtt aagccagttg aagaaagtgc ctgcatcaat tcttttccag
     4681 cttgaccgct aaaaggaaca tgcgtatcaa tctctgtttt ccctggggct tctcccacga
     4741 gcatcagttt aggatgaaga ggtccttgcc cagcgataaa tccttctaca ggacggccgt
     4801 tcattcttaa agaagcttct tgtatcagtt cttttgggta ttccatttat gctcctcctt
     4861 tttcttttat tataagaata aaagaaacac aatgcgacta ttttatttgg tagaactgtg
     4921 aggatagaaa agcagaagta ttgcttgaat ttttgtttta ctttttgatt ttaaatttag
     4981 ttgactaacg gttgctgttc tggtaagcta gtactgttgt aattgtggac tccacagcta
     5041 caaccgctca gaacaagtaa taagcacagc atatgctgtc acttcggatg gcgagtctaa
     5101 gtatatcaga aggaggtgct ttatagcatg tacgcaatta ttaaaactgg tggtaaacaa
     5161 gtaaaagttg aagtgggaca agcaatctat gttgaaaaac ttgacgttga agcaggagaa
     5221 aaagttgttt ttgacgaagt tatcttagta ggcggagaat ctacaaaagt aggcgctcca
     5281 actgttgcag gtgcaactgt tgaaggtact gttgaaaaac acggcaaaca aaagaaagtc
     5341 gttactttca aatacaaacc taaaaaacat tcacaccgta aacaaggtca tcgtcaacca
     5401 tatacaaaag tggttatcga cgcgatcaac gcttaatagc gtttgagaaa gaaggcctat
     5461 atatgatcaa aggaacattt aagcgaaatg acgcaggtca gatcgtttca ttcactttga
     5521 ccgggcatgc tgatgctggt ccttatggaa gtgatatcgt ttgtgcgggt gtttctgcgt
     5581 tagcgatcag cactgtcaac gggattgcct cattagccgg ttttgagccg attgttgaaa
     5641 tgaatgaaga agaaggcggt tatctttata ccgaagtcac ttcaggaatg acacaagaac
     5701 aaaacaatat tgctgagatt ctattagaaa atcttttatt aggattacaa tcgatagaag
     5761 ctgaaaactc agaatatatc caaattaaaa caattaatga taaataggag gtgcagacca
     5821 tgttgttatc tatgaatcta caattatttg cccacaaaaa aggtggcggt tctacatcta
     5881 acggccgtga ctcagaatca aaacgtctag gtgctaaacg tgctgatgga caaacagtta
     5941 caggtggatc aattctttac cgtcaacgcg gtacaaaaat ctatccaggt gtaaacgtgg
     6001 gtatcggtgg agacgacact ttatttgcaa aagttgatgg cgtagtacgt ttcgaacgta
     6061 aaggccgtaa caaaaaacaa gtgtctgttt atccagtagc tcaagaagct taattgaatc
     6121 ttatgattaa agaggttgtg acaagacttt tgtcacagcc ttttttgttt ataaaaataa
     6181 aagttgtagt ggaggctacg aagtttactt tgtcttttta cacttaatat ttttttgcca
     6241 atttggaatc aggatgtttt gataactatc gttttcaatt gatggaagct atattgtttg
     6301 ctatcagtga aataattata tggtaaacag tgttcttttt cttgtttcca ttataaaaat
     6361 cgtatcggga tttttcgttc ttttaaattg aacatttcta tctatccgcg tgttatcaac
     6421 aaaacaaaat caggtaaata gttgacgaaa cagaaataaa tacatagtat tatgttttga
     6481 agcctaagta caatagtcta tagaaaagga gcgataccat tggcaaaacg cattgaccga
     6541 atttatatgt atgtcaaaga aaaaaccgct catttaacaa aggcagaata tgatcaagga
     6601 gtaacaacac aggaaattgc tgaagtgtta gggattcagc gaacaaatag cagtaaagat
     6661 ctgaatcagc tagtgcgcga aggaaaactg ataaagacag acggacgacc agtacgttac
     6721 atatatcaaa cactcgttac gcacgtaaag ccagttacaa aacatgtagt cagttacaaa
     6781 gaaacgccgg tctctgaaga aaaaaataca ctccaaatag atactaagga tatctttgca
     6841 aaaatcattg gagctaacgg cagcatgaaa aattcagtgg aacaggcaaa agctgcgatt
     6901 ttgtatccgc caagaggatt aaattgtttg attacaggac ctaccggatc aggaaagact
     6961 tattttgcac acgcgatgta tcattttgca aaagcgcatc atgtaataga tgaggaaacg
     7021 gaactgattg ttttcaattg tgctgattat gccaataacc ctgagctttt gatgagtcat
     7081 ttatttgggt acgcaaaagg tgcttttaca ggcgcagatg aagaaaaaat ggggattatc
     7141 gatcaagcgg atggcggtat gctgtttttg gatgagattc accggttgcc gcctgaaggt
     7201 caagaaatga tcttttactt tatggatcat ggaacttaca gtcgtcttgg ggaaacaacg
     7261 aaatcccatg aagcaaatgt acggatcgta ggtgcgacca cagaagaccc aggttcttct
     7321 ctattagaaa cttttgttcg gcgtatccca atcaatatca aacttccggc ttttgaaaaa
     7381 cgtcctgcaa atgagaaagt cgatttagta aaaatcatga ttgcccacga agcaaaccgc
     7441 acgcagcgaa agatttcttt gacagaagat gtagcaaaag cattgatcgg cagtgtgacc
     7501 tatggaaata taggacaatt gaagtcaaat atccagttag tatgtgcacg aggatttcta
     7561 aatcatatgc aatcacccga aatctcgatc acaatcgatg atttgacaga agggattcgt
     7621 agcggattga ttcaattagc aagcaaccgc agtgcaatgg cagagctttc taaaatattg
     7681 gagccaaaga taactgtagc accaaatgat acgatcatga aaatccaatc ggactcctat
     7741 gagttacctt ataatctata tgatatcatc ggagataaag cagctttact gaagtcggat
     7801 ggtttggatc aagaagcaat caatcatttc atttctacag atatcaacat ccatctgaag
     7861 tctttctata aagaccatgg tttttctttt aatgcagaca gcaaattagc agaatttgta
     7921 gatccgaaaa tcatagaagt gaccaatcag atttatgtaa tggtcaaaag atctttacca
     7981 tatgagtttc agcaaaactt tatttatgct atgagcttgc atatcagttc ttttttgaaa
     8041 aaaatcaact taggagaaga acggcatacg aatgataaca tccgtgagat ggcttttgat
     8101 tttccagatg aatatgctgt tgcgaaagaa gtgcgtagtt atatcgaaac gtattttcaa
     8161 gtggagattc cagaaagtga agactattac ttgaccgttc tactcgtctc gttacgggca
     8221 aatcaagcaa gcggcagaat cggtgtagtc gttgcagctc acggaaacag cacagcaagc
     8281 agtatggtcc aagttgtcca acagttgtta gatgcagaga acgtacgagc agtagacatg
     8341 cctttggata tggatccgaa aacagcattg gaccgaattg aacgcaatgt acaagaagta
     8401 gatgaaggaa gcggggtcat actcttagta gatatggggt cccttgcgtc gtttaattcg
     8461 caaattcaaa gagacactgg aattccagta cgtactgttg atatggtaac aacttctcta
     8521 gttttggaaa ctgtacgaaa ggtctcagta ttagggacag atctagatat gttgcatgaa
     8581 tcattgaaaa attttcgagg ttacgcagaa atatcttctg tagaatctgt tcaggaagca
     8641 aaacctattc ataagaaaaa agctgttttg gctatctgcg catctggcga aggtacagca
     8701 caaagaatca aagaattgat cgaacgagcg gtaaacaagc gtcaagaaac agaattagaa
     8761 gttctagctt tgtcgattgt ggaagtgaaa gaagaactgc cagttatcca aaaagaatat
     8821 cagatcatag ctactactgg gattactgat ttgaatatcc aagccccatt tattccttta
     8881 gaacgtttta ttgatcaaaa tatcgaagtc attttggatc agttgctgat ggaatcagaa
     8941 ttggaggaaa ctgaattcat ctccctagat gaagagtcag ctaaaaatac gtgtgttgag
     9001 tttatctctg ataacttcat ctttattaat ggtagtaagt taatcgatcc aatgtggcaa
     9061 ttttctacac aaatctctca gacgacggga atcggcgatg aagaatatgg attcaaaatc
     9121 aacctagtga tgcacacagc aggaatgatc gaacgtatta ttcggaatga accattgact
     9181 gtggaagaaa acgaattgac aaatacaacg aatgatcctc tttatagcca attggcagcc
     9241 tcagttgttc tgttggaaga tcagataaaa gtaaaagtgc cgatagaaga aatgtattat
     9301 ctgctacgtc tagtccataa tcagttagat aaaaaagaat acactgtgcc atgaatacac
     9361 aaaaacgata cacttttata gtgtatcgtt tttgtgtatt ggttaagaat cctttaaatt
     9421 caattagtgt atcgtaaaaa agttggcacg ctttttgctt atagtagtgt gtgctaggag
     9481 gtggttgttc acacagaaat gataggggtt tctgtgaagt agtgaggaag aaggagtttt
     9541 gcagatggat attcgattgg cacgtataga tgatcgttta atccacgggc aagtcgcaac
     9601 agtttggtcg aagcaaacag gtgttgaacg tatcattgtg atcagcgatg tagtcgctca
     9661 agataaattg agaaagtttc tactaaaaga agctgcaccg ccggggatca cagcaaatgt
     9721 aataaccgtg cagaaaatga ttcaaatcta tcatagtgga ttattatcac gagcaaaagt
     9781 gatgctttta ttcaccaatc cccaagatgt tgaagcggtt gtccgctgcg gtgtacagtt
     9841 gaagtcgttg aatatcggcg gtatgagttt tactgaaggc aaatcaatga ttaccaattt
     9901 tgtttcagta aatcaacaag atattgattc ctttcgttac ttgaacagtc aagaagtgga
     9961 gttagagatt cgaaaagtac ctgctgacag gaaaatcctt ttgatggaac tactagcgaa
    10021 aatcaaaaag gtgtagcaag aatggttgtt ggaaaaggtc aaataattct gttgtaatgg
    10081 ttagcaatta ttaatatttt tgaatttgtt acaacaaaag taaataggag gtataaatat
    10141 ggtagggatt atcctagcaa gtcatggaca atttgctgaa ggaatcttac aatccggttc
    10201 aatgatcttt ggcgaacaag aaaacgtcaa agccgtgatt ttgaaaccaa gtgaaggtcc
    10261 agatgacttg agagccaaat tggaagaagc ggttgcttct tttgataatc aagacgaagt
    10321 gttattctta gttgatttat ggggcggaac accgttcaat caatcaaaca cattattcga
    10381 agagcacaaa gataaatggg caatcgtcag cggtttgaat ttaccaatgt tgattgaagc
    10441 ctacgcatca cgcttttcaa tggaatctgc tcatgaaatt gcagcacaca tcattgaaac
    10501 agcaaaagac ggtgtaaaag taaaaccgga agaattagaa ccggcagaag caccgaaagc
    10561 agcagttgaa gacgcacaac ctaaaggagc acttccagaa ggaactgtgg tcggagacgg
    10621 aaaaatcaaa tatgtattag cacgtgttga ctcacgtctg ttacatggac aagttgcgac
    10681 agcttggaca aaagcagtgc aaccaaaccg tattatcgtt gtttcagatg cagtatcaaa
    10741 ggatgatctg cgtaagagac taatcgaaca agctgctcct ccaggtgtaa aagcaaatgt
    10801 tattcctatt agcaaaatga tcgaagtagc aaaagaccct cgttttggaa ataccaaagc
    10861 attgctttta tttgaaaatc ctgaagacgt attgacagct gttgaaggtg gcgtagacat
    10921 caaagaatta aatgttgggt caatggcgca ttcggtcggt aaagtcgttg taagtaaagt
    10981 attgtctatg ggacaagaag acgttgaagc gtttgagaag cttgaacaaa aaggtgtgaa
    11041 attcgatgta cgtaaagtac ctaatgattc acgcgataac atggatgata ttttgaaaaa
    11101 agcaaaagct gaattagcaa aagcgtaata aataatatta aaatttatag gaggcttatc
    11161 atgtctatta tttcaataat tttagtcgta ttagttgcct ttctagctgg tatggaaggt
    11221 attcttgatg aatttcaatt tcatcaacca ctagtggcat gtacattgat cggtttagtt
    11281 accggtaacc tcgaagctgg tatcgtactt ggcggtacgc ttcagatgat cgctttaggt
    11341 tgggcaaata tcggtgccgc tgtagcacca gatgctgcat tagcatcagt agcatcagca
    11401 attattttag ttttaggtgg acaaggtgtt aaaggtgttc cttctgcgat cgcgattgcc
    11461 gttcctttgg ctgttgcagg gttgttctta acaatgatcg tacgtacaat cgctgttcca
    11521 atcgttcatt tgatggatgc ggctgctgaa gaaggaaaca tccgtaaggt tgaaatgtgg
    11581 cacatcattg ctgtatgttt acaaggggtt cgtatcgcgg tcccagcagc agcgttgcta
    11641 tttatcccag cacaaactgt gcaatcattc cttgaatcaa tgccagcatg gttaacagat
    11701 ggtatggcta tcggtggggg aatggtcgta gctgtaggtt acgctttggt aatcaacatg
    11761 atggctacaa aagaagtatg gccattcttc gttattggtt tcgttgtagc tgcaatttct
    11821 caattaacat tgattgctct aggtgcttta ggtgttgcat tagctcttat ttacttgaac
    11881 ctttctaaaa tgggtggttc atcaaataat ggaggcggaa gcaactctgg tgacccttta
    11941 ggcgacattt tgaatgacta ttaatcttga aggaggaaaa taaaatggca gaagaaaaaa
    12001 tcaaattatc aaaaaaagat cgtttagctg ttgcgtggcg ctctaccttc attcaaggtt
    12061 catggaacta cgaacgtatg caaaacggtg gctgggcatt ttctatgatt ccagcaatca
    12121 aaaaattata caaaacaaaa gaagaacgtt ctgcagcatt aaaacgtcac ttggaattct
    12181 ttaatacaca cccatacatt gcttctccaa ttttaggggt tacattggct ctggaagaag
    12241 aacgtgcgaa tggcgcgcct gttgatgatg tagcgattca aggggttaaa gtaggtatga
    12301 tgggtccttt agctggtgtt ggtgacccag tgttctggtt tacagtacgt ccaatgctag
    12361 gtgcactagg tgcttcatta gctatgggag gaaatatcct tggaccaatc atcttcttct
    12421 taggttggaa cattattcgt tgggcattca tgtggtatac acaagaattt ggctacaaag
    12481 ctggttctaa aattactgat gacctttctg gcggattgtt acaagacgta acaaaaggtg
    12541 cttcaatttt agggatgttc gtattagctg cccttgtaca aagatgggta tcaatcaaat
    12601 tcttaccagt tgtatcaact gtaaaattag ataaaggtgc ttacatcgaa tgggataaat
    12661 tgccttcagg tggtgaagga atcaagagtg catttgaaca agttaataat ggcttagccc
    12721 tttctcctga aaaggtaaca acattacaag acaacttaga ccaattgatt cctggtttag
    12781 ctgcattagg attaacattg ttatgtatgt ggttgcttaa gaaaaaggtt tctccaatcg
    12841 ttatcatcct tggtttattc gtagtcggtg ttgttggaca cgtcatcgga cttttataat
    12901 ccataaaaat atagctcggg cgttgtcccg agcttttttt atatagtata ctgttcataa
    12961 acaaatatct ggagggagaa aatggttcaa tcaatcaata caaaagtaga cttggtaatt
    13021 gatgctactt cgtttacggg tctgacagat tacgggcaaa tcatgatagg taataatggt
    13081 tttgagtttt accatgcgcg agatagacgc aaatatatcc aaattccatg ggaagaagtg
    13141 gattatgtac tagcatcagt catgctaaag ggaaaatgga ttcctcgata tgccattcaa
    13201 acgaaaaaaa atggtacata cacattttct tccaaagaac ctaaaaaagt gcttcgtgcg
    13261 atcagagaat atgtagatga agatagaatg gtacaatcat tgagtttctt tgatgtagtg
    13321 aaacgtggta ttcgtagtat gtttaaacgc aagtaaaaaa taaagaaaac ttctaagagg
    13381 aggttttctt tattttttta ctttgcagaa gaaaatatga aatagcaaaa ccaattattt
    13441 gtccccttta aatcccatat gctaaaattg attagcaaag aaggaggtta tattatgagt
    13501 tggttatgga cattgattgt tggagccgtg atcggagcaa ttgcaggtgc gatcaccagt
    13561 aaaggaaatt cgatgggctg tgtaacgaat atcattgctg gactagtcgg ttcaagtatt
    13621 ggacaagcga ttttcggcga atggggacca aaagctgcag gtatggcact tattccatct
    13681 attttaggcg cagtgatttt ggtagcagtt gtctcatttt tctttggaaa acgatcataa
    13741 gtttttacaa aatagtaaac taaaaggagt tgcagcgaga ctgtgactcc tttttggctt
    13801 tatttattta aaataaaaag aagttttccg gaaattttta tttaactgtc gtgtacgaag
    13861 aaaagtttgc tataatggaa aaaagcgtgc aaagaaagag ggagtttcat tatgatgcta
    13921 cgtgtagaaa aattgcgcaa aaaaatgcaa gaagaaaatt tggattcatt tttggttacc
    13981 agtccgtaca atcttcgtta cttaacgaac tttacaggta cgacaggatt agctgttatt
    14041 actttggaaa aagcattttt tattactgat tttcgttata ccgagcaggc ggcagcgcag
    14101 gctcaagggt ttgaaattat taaaaatgtc ggacctattt ttgatgaggt agcaaactta
    14161 gtacgcaaag aagaactgca ctcattagct tttgaggaaa caacagtctc atttttagaa
    14221 tattcggttt tagaagaaat catcgatgcg gaattagtac ctgtttcaca gatgatcgaa
    14281 gaactcagag aagtgaaaga tgaagaagaa atcgctatta tcgaaaaagc atgtcatatt
    14341 gcggatatgg catatgatca catcctgaaa atgatccaac cgggcatgac tgagattgaa
    14401 gtcgcaaatc aactagactt ttatatgcgt tctcttggcg cttcaggtgt ttcttttgat
    14461 acgatcgttg ctagcggatt gcgttcggct atgccgcatg gtgtagcaag caaaaaaatc
    14521 atcgaacaag gtgacttgat cacattggac tttggttgct attacgaagg gtacgtttcc
    14581 gatatgacac gtacattcgc tattggtgat cctggggaaa aattaaaaga aatttatcaa
    14641 atagtcttag atgctcaatt agcagttatt gatgctgcaa aaccaggaat gactggtgtc
    14701 caattagatg cagttgctag agattatatt tcaaaacatg gttacgggga agcatttgga
    14761 cattctacag gacatgggat cggtttagag atccacgaag gaccaaacgt ttcttctcgt
    14821 gcagaaaagc aatttgtacc aggaaatgtg atcactgatg aaccagggat ctacttacca
    14881 ggaatcggtg gagtacgtat tgaggatgac ttgttgatca cagaagatgg aaatcgtgtg
    14941 ttgactcgtt caccaaaaga attgatcatc ttatagtttc atcaatagaa gaagtaagcg
    15001 taaaaatcag tgttcacaga ctttgttata gaaaatcact cgatttaatg atacactata
    15061 gaagaacttt taagctgtaa gagataataa agttgggtgt tttctccaat tcatagcagt
    15121 ttgcagctga tcggcggcag ttttcttacc acgtgatcac tatgccgcat catagagaat
    15181 tcggatgtat ctcgtgctta ggcaaaggga ggaataaata aatggcagat gaaaaaaatt
    15241 tgattttaaa cgcaaaccaa gatttaggag agatcgtgat cgctcctgaa gtcatcgaag
    15301 taattatcgg gattgcagct tctaaagtag aaggcgtata cggaatgcgc ggaacttttg
    15361 ccagcaatgt cactgaatta ttaggacgtg cagctcacgg aaaaggtgtt tacttagcaa
    15421 acgaggaaga tggcttgaaa gtagatcttt actgttatct agaatatggt gtttcagttc
    15481 ctaaagtagc aatggaaatg caggaacggg tcagccagca agtccttttc atgacggata
    15541 tcgatttatc tgaagtcaat atccatgtag tagctgttgt tcctgaaaaa ttagaacaac
    15601 caacaatcga agaacttttt gaagacgaag aggaagagaa tgaataaaga attatcaaga
    15661 cacgagattc gggaaatggc attgcaggct ttatttccat tagacttcaa tgcagaccta
    15721 acaaaagaag atgcgatttt caacgcaatc gaattagacc accgcgacat gatcaacgaa
    15781 gatgaatcag agtttgttcc tgtttatctt gatacgctag ttggcggtgt ctgtgcaaaa
    15841 aaagatgaat tggataaagt gattgaaaaa catttaaaaa acaattggca catcaatcgg
    15901 atctcaaaaa tggatttggt gatcttgcgt atcgcgattt ttgaaatgac ttatgtgaca
    15961 gatgtaccag cggctgttgc tttaaatgaa gcaatcgagt tggcaaaaac atttagtgat
    16021 gaccgttcac gtaaattcgt caacggtgtt ttatccaatg tattgaaaga attagaagct
    16081 ggggcgtaag tcctagcttt tttctatgaa tcatcataaa cctgttataa atcgggaaaa
    16141 ttctatggta gaatgaaaac acaaaaaata tctgggagtg gttagatggc agaattgatt
    16201 aacggaaaag aattagctga aaaaatgcag gcagagattg ctgaaaaaat ccaaaaattg
    16261 aaagataatg gtatccatcc cggattagtc gttttattgg taggggaaaa tccagccagc
    16321 caaatctatg taagaaataa agaacgtgta gcaaaagaaa tcggaatcca ttcattggta
    16381 gagcgttatc ctgagacgat ttctgaagac gaactacttg cagaaattga aaaatacaat
    16441 caagatccta gttttcatgg tatattggtc caattaccat tgccaaagca tatagatgaa
    16501 gaaaagatcc tgttagctat ccgccctgaa aaagacgtag acggttttca tccgatgaat
    16561 ttaggcagac tccttgcggg taaaccggac aagattcctt gtactccata cggcatcatg
    16621 aaaatgtttg aagcttattc tatcgatccg gcgggtaaac gagcagtagt tatcggacga
    16681 agcaatatcg tcggtaaacc gatggctcag ctactcttga tggcagatgc aactgttact
    16741 gttgctcatt ctaaaaccga aaatctggct gaactggcac aagaagcaga tattttagtc
    16801 gtagcaatag gacgtggaca ttttgtcaca aaagaattcg taaaaccagg tgctgtagtg
    16861 atagatgtag ggatgaatcg tgatgctaac ggtaagctga tcggtgatgt gaaatttgat
    16921 gaagtggagc ctattgcagg ctggatcact cctgtgccaa agggtgtagg gccaatgact
    16981 atcacgatgc tgatgtatca aaccgtaaaa tctgccgaag cttttggagc aggtgaatag
    17041 atggcacaag aatatttaac tgtcactaca ttaacgaagt atttgaaaag aaaatttgat
    17101 gccgatcctt atttagaacg cgtatattta acaggcgaaa tatcgaattt ccgtttacgt
    17161 gccaatgccc atcaatattt cagcttaaaa gatgaccatg caaaaatatc tgctattatg
    17221 ttcaaaggag cattccaaaa attacgattc cagccaaaag aaggaatgaa agtccttgtc
    17281 gttgggcgta tttcattata tgaagcggga ggttcttatc aaatctatgt agagcacatg
    17341 gagcctgatg gaataggtgc tttatatcaa gaattggaag aacgaaaaga aaagctgatg
    17401 aaggaaggcc tttttcaagg gcctaaaaaa atgctgccac gtttcccaaa gcgaatcgcg
    17461 gtccttacca gtccaagcgg agcggttatc cgcgatatca tcacgacggt gaaaagaaga
    17521 tatccaattg tccaattggt tttgttccca acagttgtac aaggaaacca agcagcggac
    17581 aatgttgtca ggaatatcca gagagtagaa gagatgggca atttcgatac aatgatcatc
    17641 ggtcgtgggg gtggttcgat tgaggattta tggccgttta atgaagagcg ggttgctcgg
    17701 gcgatttatc aagctaatac gccggtgatt tcatctgtag gacatgaaac agataccacg
    17761 atcgctgatt tagtagcaga tgttcgggct gccactccaa cagcagctgc agaattagct
    17821 gttcctgttt tgtcagaaga gttgatgcgc attcaagaac ggcaagctag attgcagcag
    17881 gcgtttgtac gccagatcca gcgcaaacaa gaacggttcg agcgtgctcg acgttcctat
    17941 gtatttcggc agcctgaaag attgtatgaa ggtcagacca tcaaattaga ccagttgaaa
    18001 cagcgattat atcaagctac acagcaaatt tatcatgcga aagaaaaaca aacgatcgca
    18061 ttaagccacc aattggaaca agtggctccg ctttatcgag ttaaagcagc tcgccaagaa
    18121 actgcttatc tagaaaaacg cttagaagag aaaatccaac aatatatgaa acaacagcag
    18181 cagcgttttg ctcaagctgt tcaatctctt gatttgttga gtccattgaa aatcatggga
    18241 agaggctaca gctatacgac gttaaatgat caagtagtaa aaagtgtcac cgagattcat
    18301 caaggggatt tgctgacgat ccattatcaa gatggaatcg ttaaaggaca agtacaagag
    18361 atagacaaag gagaataaaa atatggaaaa tccaactttt gaagagtcac tgcaagaatt
    18421 agaaaaaatt gtcatgcagt tagaacaagg agacgttcca ttagaatcag ctctagattc
    18481 gtttaaacga ggaatggaat taagcaaaca ttgccaagat acattagcta aagcagaaga
    18541 gaccttgacg aaaatgatga cagaatcaaa tgaagaagtt gattttgacg gaaacgagga
    18601 aagctgagat gagattaact gacttttcag ctattcatct acctgctgta gaaaaagaaa
    18661 tcttgtcttt tttagatgag catacaacgg atagaggact ctatgatgcg atgagttatt
    18721 cagtgaaagc aggcgggaaa agaatacgtc ccttattact tttaacggcc gttgcttcct
    18781 ttgatgagcc tattgatgtt cccgtctatc aagtagcagc tgctttagaa atggtgcata
    18841 cgtattcctt gatccacgat gatttgcctg cgatggacaa tgatgatctt cgtagaggaa
    18901 aacctaccaa tcataaagta ttcggcgaag cattagctat attggccgga gatggtttgc
    18961 ttacaggagc attccagcta atcagtatgg cacacttagg taattctcct aagcttctgc
    19021 tgcttcagca attagctgtt tgtgcgggat cacaaggtat ggttgctggg caagctgcag
    19081 atatcgaggg cgaatcgaaa aagctttctt tagaagaatt agcatttatt catgaaagaa
    19141 agacagggca tttgattcgt tatgccttgc tggctggtgg catattagcg aagcaacctg
    19201 aagaaatctt attgctactt caacgattag ccgaacattt aggtttagct tttcagataa
    19261 gagatgatct actcgatgtg attggtacaa cgaaaacatt agggaaaaca gctggtaaag
    19321 atgaacgtat ggaaaaaaat acttacccgc gtttattagg cctagaaaag acacgtgagg
    19381 cgttggagat tgagctgtta tccgccaaca agatcataga caaattagaa gaggacgttt
    19441 tttcttttga tggcgggctg atgcgccaga tgatcaagca atttgatgtg gagaaatgag
    19501 ggaaagaatg gaaaaagaac gcgtagatgt attagcggtc aaacaaggat tatttgaaac
    19561 aagagaacaa gccaaacgtt cagtgatggc tggtttgatt tacaacgaaa aaaacgagcg
    19621 gtttgataaa ccgggagaaa aaattccagt gagtagtgaa ttaagagtca aaggtaaaaa
    19681 acttccttat gtttctcgag ggggattaaa attagaaaaa gcactcaaag catttgatct
    19741 atctgttgaa ggaaaaacat tgttagatat tggtgcatcc actggcggat ttactgatgc
    19801 agctttgcaa aatggcgcaa aaatgagtta tgctttagac gttggctaca atcagctagc
    19861 ttggaaaata agacaagatc ctagagtcgt cgtaatggaa agagtgaatt ttcgttatgc
    19921 aaaacccgaa gactttacct taggaattcc agaagttgct gttatcgatg tttcttttat
    19981 ttcactaaaa ctgatgctgc ctccattaca tgctatttta aaagaagagg gagaagtgat
    20041 tgctttaatc aaaccccaat tcgaagcagg cagagaagct gtagggaaaa acggaattgt
    20101 tcgtgaccct cagacccatc aaaaagtttt agaagacatt ttgtcatttg cggcacaagg
    20161 tggatatgat gtgctggaat taagttattc tccgatcacg gggggagaag gaaatatcga
    20221 gttcttggct cacttgagga aagtacccga aagcggaaca atcaattcag ctattaatat
    20281 ggcagaagtg gtttcaaatg cacacgaaca gtttgaccat aaataaattg taactgtgaa
    20341 aatcaagtga gaagtatgcg gattcttctt tattatacca aggaaataag ctatcattga
    20401 ttaagaagaa tatgctaagg agcgaagacg taatgagaaa aaaagatcgg catcgtttga
    20461 ttactcgatt gttgagtgag caagatatcc gaaagcagga agaatttgtt gaaatcctga
    20521 aaagcaaagg aatatctgtt actcaagcta cgatttccag agatataaag gaactgaaac
    20581 tgatcaaggt accggcttca gatggcggct accgttatag cataccagct gaaacaaacg
    20641 aagatgtaaa tactaaattg gaaaaactat taaaagacgc tttcgtggca gttgaccaaa
    20701 tggaaaaatt tgttattttg aaaacattgc cgggaaatgc ttcggcagca gcaaatttga
    20761 ttgataaacg ttacaagaaa gaattatttt cgattatcaa tgatgacgat aatgttttga
    20821 tgattacacg aactgaagac caggcagttt tattgaagaa agacttcctg cattaccttt
    20881 aagttgagga gcgaatgtga tgctacaaga aatcagtatt actaactttg cgattattcc
    20941 ggaattgcgg ctttcttttc acgaaggaat gaccgcgctg accggagaga ctggtgcggg
    21001 taaatccatt attatcgatg ctttaggtct gttagcagga ggaagaggtt caagcgatta
    21061 tatacgtcaa ggagcagaaa aatgtgtgct tgaagggttg tttgaactac caaaacaaga
    21121 aggattctct gaactgatgg ttgaattagg gatcgaaaca gatgaggaca atctgattgt
    21181 tcgacgggat atgtccttaa ctggaaaaaa tgtttgtcga gtgaatggtc atattatcac
    21241 attagctaat ctgagaagaa tcggcagtta tttagtagat atccaaggac aaaacgaaca
    21301 tcaggaactg ctccagcctg aatcacatct tgctttattg gatcgttttg gagatgtagc
    21361 tttccaacag aagaaaaaga gttatcagca agaatatatc tcttatcgtg agctggaaaa
    21421 aagggtacga aaagtgcagc aaaatgaaaa atcctatgtt cagagaatag atatgctcca
    21481 tttccagcaa gaagaaatag ctgctgctga tttgcaagtc ggagaagaag agaaattaaa
    21541 agaagaaaga gaaaaactta gcaattatca aaaaattgct gatggattag ctgcaggtta
    21601 cggagcactg acgaataatg aacaaaacag tgtagatggt gttggcttgg ccgtttcaga
    21661 actgcaaggg atcgcccatc tagatgtgga gtatgaagca atttatgaaa atatccaaag
    21721 tgcttactat ttgctgcaag atgcaatcgg cgatatgagt cgtcagattg atttattgga
    21781 gttagatgag agtcgtttag aagaagttac gcaacgttta gaattaatcc gacagttgaa
    21841 acgtaaatac ggcgaatcca ttgagtcaat attggcttac tatgacgaaa tcaccgaaga
    21901 gctagcttct tctgattttt cagaaggtca attggacaaa atgaaagagg aactagagca
    21961 aaaagagctt ctacttcagc aacaagccgc agatcttcat gaagcgcgta aaaaaatcgc
    22021 aaaagaattg gaaaaatcca ttctgcatga attgaaaagt ctgtatatgg aaaacactga
    22081 gtttgaggta cgtttcttaa aagaagaaaa tagacaattg aatcatgatg gatttgacca
    22141 aatcgaattt tacattacga ccaatccagg agagccactg aagcctttgg tgaaagtcgc
    22201 ttctggtggc gaactgtctc ggatgttgct tgctttgaaa actatttttt cttctgagca
    22261 aggtgtgaca agtattattt ttgatgaagt ggatacaggt gtgagcggaa gagttgcaca
    22321 ggccatcgca gataaaattt ctcaaatatc gaaatactct caagttttgt gcatcactca
    22381 tctgcctcaa gttgctgcag tcgccgacta tcaatattat attgtgaaag cagtgattga
    22441 tggacgtacg caaacttctg tttcagagtt gaaaacaaaa gaaagagaag aagaaattgc
    22501 acgtatgctg gctggaagtg agattacaaa actcacactc gaacatgcaa aagaactatt
    22561 gaaactcgca aaaaggacct gagccacctc gcagtggttc aggtcctttt cagcagctga
    22621 tagctatatt ttatttttac atgacactca ttacagcagt caatacaaca gatccaatcg
    22681 ttaaaatcag cattgtccaa atgacaaatt ttgttacttt agcaaaagta cttgtttgtt
    22741 ttttttcacg cattgttttc aacctcgtca ttaattagtt gattcaagtg tacaatcttt
    22801 tttccatttc cacaagaggg cttttttata aaaacttccc tttttttaaa taataggtag
    22861 ttacgataca aataaataat gttaatagaa ctagccatat aaaggcatca tccctttcag
    22921 caataggtaa cttaatgttc attccataga tactgccgac gattgtcggt atagttaaaa
    22981 taatcgttaa agaagttaaa attttcataa tattattcag attattcgat acgattgctg
    23041 aaaaagtctg attcatttgt tctactagtt ttaattgaat gcgagaagta gtcattgcct
    23101 gctctgtttc caccaataca tcacgtaaat gatttttcaa agcatgattt tcttggaaaa
    23161 gtttattttg cgctagttct ttcaatgcat ctaaattagc agaagtcgct tctctgaaat
    23221 aaacgaggct tttttggata tccatgattt gataaagttg tttgttttca gtggatactt
    23281 gaagtttggc ttccaaagta tcgcattgag attgaagcgt agctaaataa ctgttgtaag
    23341 agagtgtgac ctgccaaatg aattgaaaga agatattgag attaggcgaa atatcacttt
    23401 ttggaaaggt ctggctaaag actttcttta aaaacagtgg ttcatgattc gtaattgtga
    23461 taagcttctt tttgggcgtc aaaataatag agagcgggta tgtatccact tgaaaataac
    23521 cgctaggact tgttttagca aaaggatatt gtaacaataa taacgctggc tttgtcaact
    23581 ttgattgatt gaattcttct gtacgggaat tttctgcatc gtccaatatg gaagtgatgt
    23641 aatctgacgg aatttcaaat tgatgtgtca gctgatgaat ctcttcttga ttaggacgtt
    23701 ctacacaata ccagatcgtt tggtcagttt cctttccggt attacgcagt ttctcattat
    23761 ctaatgtaaa atatttgatc atgattttcc tcctgttgcc tgtttctttt attataacgg
    23821 atagggaatt ggaatacatg gaatgtgttt gtaagatata gaatataact gcataaattt
    23881 aaataaaatg aaacagttgt gtaaagtata tacagtatac ttgaagcaac gataaaaaag
    23941 gagtttacgt tcatgggcac attcacacca cttatcttgt tttggtatat ttacccggta
    24001 atcgttttgt ttggttgcca atttcttgta aaattatttt cgttaaatcg tcgttttaaa
    24061 ataaaagccc ctgatttggc gattcctttt ttgtggggcg gtatgcatgc attgtctaga
    24121 aatacaggga caatttctat cttaccgttt ttctttattt ctgttttgct aatgggaatt
    24181 tgtattgctg ttttccaagc atattattat gaagaaatta tttatccgcg ttatttcaag
    24241 atgacttggc gtttggtttt tctgttgaca atcgtcttgt acgctgtctt gatcattgtg
    24301 aacatacttt cttacctatg aaaaaaatag aaaagctgta aaaagtcttt taaaaggctt
    24361 tttgcagctt gatttttaaa aaaatgttta tgaataaaaa aagttgttcc cggatttccc
    24421 agaaaaggtg gtagaaagtg ggggattgtg gtagactaat tttagttagt ggaggaatgg
    24481 ggggctttca atgttgatgg gtgaattcca acataatatt gatgcaaaag gacgtttaat
    24541 cgtgccctca aaacttcgtg aagaacttgg cgaaaagttt gttctgacac gcggattgga
    24601 tggctgtctt ttcggctatc cgatgagcga atgggaaaat ctggaagcta aactgaacga
    24661 aatgccgttg gctaaaaaag acgcacgtac ttttgtgcga ttcttctatt cggctgccac
    24721 tgaatgcgaa cttgataaac aaggacgaat caatataccc agcacgttaa gaaattatgc
    24781 agctttgaca aaaggttgcg tagtcatcgg tgtatctaac cgaattgaaa tttgggatga
    24841 gacacgatgg caagattttt ctgcagcagc agaagagaac tttgacgaaa ttgctgaaag
    24901 tatgattgat ttcggactat aagaatagga agaggctgac taatgactga aacatttcaa
    24961 cactatacag tcatgttgaa agaaacggta gatggattga acatcaaacc ggatggcgtt
    25021 tatgtagact gtacactcgg cggtgccgga catagtgaat atttattaag ccaactaagt
    25081 tctaaagggc atctgtatgc gtttgaccaa gatcaaaaag caatcgatca cgccaagctg
    25141 cgtttagctt cttatgtcga acaaggtatg gtcacattta tcaaagcgaa cttcagagaa
    25201 ttagaagaac gcttgagtga gcatgtagat aaggtagacg gcattttgta tgatctaggg
    25261 gtttcctctc ctcagctaga tgaagcagaa cgtggattta gttatcatca agatgcaccg
    25321 ttggatatgc gcatggatca gtcagctcct ttatccgctt atcacgtaat taatgaatat
    25381 tcctaccatg aattagtaaa gattttcttc cgctatggcg aggagaaatt ttccaaacaa
    25441 attgctcgtg aaatcgaacg agtacgaaaa acaaaaccaa tccaaacaac tggtgagctt
    25501 gtcgaaatca ttaaacaagt catcccagct cccgcaagaa gaaaaggcgg gcatcctgca
    25561 aaaagaattt ttcaagctgt gcggattgca gtaaatgacg aactcggtgc cgaagaggcc
    25621 tctttagaac aggcaatccg gttattgaaa gtcaatggaa gaatcagcgt aatcacattc
    25681 cattcattgg aagacagaat tgtcaaaagt atgtttaaag aatatagtac ggtacaagat
    25741 ctaccaccgg gacttcctgt catacctgac gaattccaac cagaactgaa agtcattact
    25801 cgtaaaccaa tccttccttc agaggaagag ctaacagaaa acaatcgatc acgcagtgca
    25861 aagttacgta ttgcagaaaa aataagaatg aaagaggagt agaatgatgg cagaattaaa
    25921 gaaaatgcaa gattacgaat atgatttacc tgaattggtg gatcagccgg aacaacaaat
    25981 gcctgattct tcttcgaatc aagaaatcat tcttccacaa tcaccggcaa aacgattaaa
    26041 gcagatttct gctttggaaa aaattgctgt ggcaagcgtg gcgattgcta ttgttgcttt
    26101 atgtgtttta acagttatgc tgcgcacaaa tatcagcgga gctgaaaaag aaatcacgtc
    26161 aatacaaaca gaaatcaatg ataaaaagca agaaaaaacg agtttagaac aagaaaaaaa
    26221 cgaactttct cgtactgaac ggattaaaca aatcgcagaa gaaaaaggat tgtctattaa
    26281 tgacgacaat ttaaggaaag tgaagtaaat gagtcttaaa aataaaattc ggcggtttat
    26341 ggaaaagaaa aatctaaatc cgatgaacaa tcgcaaaaaa gtaggtatca ttttatttgc
    26401 tacgagtatt ggattgttct ttttatttgc cgtccgtttc tcgtatatcg ttattggagg
    26461 tcatgttgct ggtacctcat tagctgaaaa aacaaaacag ttgtaccaag gaagtgaagt
    26521 agtaaaagca aaaagaggaa cgatttatga tcgtaacggt gtggcgctcg cagaagatgc
    26581 ctcctcttat tcaattaaag cgatactctc aaaaacatat acctctgggg ataaaaaact
    26641 gtatgttgaa gaaaagaatt ttgataaaat agcagaaatc ctgcataaga atctttctat
    26701 agacaaaaaa gatgcactga atattttaga ggacggcgca aaaaaagagc tgtatcaagt
    26761 tgaatttggt agctatggga aaaatatctc ccaagaaacc aagcaaaaca tcgaagcgga
    26821 catgaaaaaa gaaggtgtcg ctggtcttta ttttgtcgac catcaggctc ggatgtatcc
    26881 aaatggcgtc ttttcttctc attttattgg atacgcagtt ccagacaaag atgagaatgg
    26941 cttagttggt aaactaggtt tggagtctgc ttacaatgat atcttgagcg gtaaagatgg
    27001 taagattatt tatcaaaaag ataattttca aaatcctctg ccaggtacag tggcagaaga
    27061 agaaaaagct gtcgacggac aagatatcta cacgacttta gacagcagac tacaaagtta
    27121 tttagaaaca ctgatggatc aagtaaatga agaatatcag ccagaagaat tgacagcagt
    27181 cctgatgaaa gcaaaaaccg gagaaatctt ggcaatggga caacgaccta ctttcaatcc
    27241 tgaaacaatg gaaggattga ctggaaaaga tgctatctgg cgtaatttct tggtacaaga
    27301 tagttatgaa ccaggatcaa ccatgaaagt tttcactact gcagctgcta tcgaagaagg
    27361 agaattcaac gagaatgaaa ccttccaatc tggaaaaatc caagtagaag atgctacgat
    27421 caatgaccat gactttggtg aaaaaggtgt gctgaccatg cgtcaagctc tttcatggtc
    27481 aagtaacgtc gggatggtca tactggaaca gcgattaggc ggacgatggt ataactattt
    27541 acaaaaactg ggatttggac aaagtactca ttctggatta gatgatgaag taaacggtgc
    27601 tttacctaca ttaaatattg tcgaccgagc aatgagtgct tatggacaag cggtaggtgt
    27661 gacgaatttc caaatgatga aagctttcac ttctattgcg aataacggta caatgattca
    27721 acctcgatat atcagcaaag tggtggatcc ccaaactgga gaagagcgaa caactcaaac
    27781 agaagttcta gggcaacctt tttcaaaaga aacaacagaa aaagtccgtg aatatatgag
    27841 agatgttgtc gaaagcgaaa actacggtag tgcttatggt gtatatagtg tacctggata
    27901 caatgtatcg gcaaaaaacg gaacagccca aatcgcttct gatacagggg gatatcaaac
    27961 aggagataca gcctacctgt attcgattgt ggagatggtt ccttctgaag atccagacta
    28021 tgtcttgtat ctaacaatga aacaccctaa gacatatgat cgaatggcat tggctaaaat
    28081 cgcaaatcca ttgatgaaac gggcaatgga ttttaaagaa actgaagaag attcagatac
    28141 agaaacaaaa acagaaaaag tatccgtagc cgattatcgt aatcttgaag cggacgttgc
    28201 agcagctgat gctcaaaaaa gtggactgca acctgtagtg atcggtaatg gtaaaaaagt
    28261 acaaaaacaa tctactgcca acggtgatca gttgatctct ggagaaaaac tgatcctata
    28321 tactggtggt gataagctga tgcctgacgt aacaggatgg tcaaaagcag atatcatgaa
    28381 gctggggaaa atcctcggta ttgaagttag ttttgatgga gatggttatt gtgtcaaaca
    28441 agaacttgct ccatatgaaa aaatcactga agacaaactt agttttactt tagaagaata
    28501 agaagagaaa taggagagaa aagagcatgg aatggacaca agcattgatt cccattgtca
    28561 gcagttgtgc aatgacaatt gccgcaatgc cgctatttat tggttatttt caaatgaaaa
    28621 agcaaggtca ggcgattcgt gaggagggac caaagtggca caatagcaaa gccggaactc
    28681 ctacaatggg cggcttagtg tttctgatcg gctctatttt gacaggaatt tgggttggag
    28741 cttggcaaaa acagctaact cctactcttt tcatcttgct ttttgtatta gcgttatacg
    28801 gagtaatcgg ctttcttgat gattttataa aaatattcaa gaaaagaaac atgggactga
    28861 actcgaagca gaaattgatt ggacagattc tagggggaat catcttttat cttgtttacc
    28921 gttctgaagg ttatccaggt gtattgaatt tcttcggact agatctacct ttaggaatca
    28981 tttatggtat tttcgctctc ttctggcttg ttggattttc aaatgcagta aatctgacag
    29041 atggcatcga tggattagtt gctggcttag gaagtatctc ttttgcagct tacggtctaa
    29101 ttgcttggca tcagcatcag tatgatgtat taatcatttg cttaagtgtt ttaggaggtt
    29161 tactgggttt cttcgtctac aacagaaaac ctgccaagat ttttatggga gatgtcggtt
    29221 cattagcgtt gggcggactt ttagcggcaa tttctataat gctaaaccaa gaatggacat
    29281 tgcttttgat tggtttgatc tatgttatgg aaacagcaag tgtgatgctt caagttactt
    29341 cctttaagct tacaggaaaa cgaattttta aaatgtctcc aattcatcat cactttgaaa
    29401 tgtgcggatg gtcggagtgg aagattgata cagttttttg gttgatcagc attgtgactt
    29461 cgttgatcac attatggatc gtttggtagg agatgacggg aaatgaaaaa aatatcaaca
    29521 tatgaaaata agaaagtgct tgtcttagga ctcgcaaaaa gcggagtaag tgcggccaaa
    29581 ttattacatg aattgggcgc acttgtcacc gttaatgatg gaaaaccttt tgacgaaaat
    29641 ccggaagcac aagagctgct ttctttaggg ataaaagtaa taacaggtag tcatccaatc
    29701 gaattgttgg atgaagaatt ttcattgatg gtcaaaaatc cagggattcc ctacagtcat
    29761 cctttagtag caaaagccca agaaatgggt attccggtaa ttacggaagt tgagctagct
    29821 tacgaagtag cggaatgccc aattattggg attacaggaa cgaacggaaa aacaacgaca
    29881 acaacgatga caggactact actgaatgca ggagcagatc aaggaattgc acgtttagcg
    29941 ggtaatattg ggtatccagc aagtggtgta gcgcaagaag caaaatcaga agataaaatt
    30001 gtgatggaat tgtctagctt ccaactcatg ggaatcacag atttccgccc tcatatagcg
    30061 gtgattacca atatctatga agcacatatt gattatcatg gtacaagaaa agaatatgtc
    30121 aaagctaaat ggaaccttca aaaaaacatg acagaaaaag attatctgat ccttaactgg
    30181 aatcagtcag aactacaaga attagcgcaa agaacaaaag cacgcgtact gcctttctcg
    30241 acaaaagaag tgttggaaga cggtgtgtat gctgacgatt actcaatata ctataaaaaa
    30301 gaaaaaataa tggaaatatc tgaacttggc gtaccaggta agcataatgt agaaaatgca
    30361 ctagctgcta tttctgtagc aaaattgtat ggtatatcaa atgaagctat acgagaaacg
    30421 ttgcattttt tccatggcgt accacatcgt acgcaatatg taggagaaat ccaaggcaga
    30481 aaattttata atgattcaaa agcaaccaat attttagcga ctaaaatggc tctaagtgga
    30541 tttgaaacgt ctaaggtcgt gttattggct ggcggattag acagaggaaa tacatttgat
    30601 gaattaattc cttcattaaa aggaatcaaa gcaatggtcg tatttggcca aacaaaagaa
    30661 aagttgatgg atgctggaaa aaaagcaggc atcgagacaa tagtaacagc cgattctgta
    30721 gaacaagcag ttcctttagc attagaaaac agtacagatg gtgatgtagt tttattatca
    30781 ccagcgaatg ccagctggga tcaataccca aattttgaaa ctagaggaaa cagattcatg
    30841 gaagctgtga accgattaaa atagaaaaag tagaagcgag cgataaaaaa tgaaaatttt
    30901 ggttacaggc ggaggaacag ggggacatat ttatccagct cttgcctttg tcaattatgt
    30961 aaagactcaa gaaccgaatg ctgaattcat gtatgtggga gcaaaacgag gtctagaaaa
    31021 caaaatcgtc cctgatacag gaatgccttt ccataccttg gagattcaag gatttaaacg
    31081 aaaaatttcc atgcataaca tcaagacggt ccgattgttt cttaagagta tccgtcaagc
    31141 aaaaaaaatc ctcagtgatt ttcaaccaga tatcgttatc ggtactggag gatatgtttc
    31201 cggagcggta gtgtacgctg cagccaaaat gggtattcca acagttatcc atgaacaaaa
    31261 cagtgtacca ggtgttacca ataaattttt aagccgatat gtggatcgga tcgctctttc
    31321 atttaaagat gcggcttcct tttttcctga aaacaaagca gttcttgtag gtaatcctcg
    31381 agcacaagaa gtagcagata ctaaaaaatc agatattttg aaaacatttg atttggatcc
    31441 agaaaagaaa acagtcttga tttttggcgg tagtcaagga gcacttaaaa tcaatcaagc
    31501 agtatcagtt tttttaagtg aatatattcc ttcttcttac caagttttgt atgcttcagg
    31561 agatagatat tatgaagaga tcctaaataa aataaatcct gaaatacaaa atattagtgt
    31621 ccagccttat atcaaaaata tggcagaggt catggcttcc agtgatctgc tggtggggcg
    31681 tgctggtgca acttcgatcg cagaattcac agctctgggg ttaccggcag tgttggttcc
    31741 cagcccatat gttacgaatg atcatcagac taaaaatgca atgagtcttg ttcacgcagg
    31801 agcagcaaaa atgattgcag ataatgaact aacaggtgaa tcactaagtc agacagtcaa
    31861 cgaaatcatg ggtgatgaag aattgcaaaa gcaaatgtgc cgagcttcta aagaacaagg
    31921 aatccctgat gcttcaaaac gtctttatga cttagtaaaa caaataatca aaaaataaag
    31981 gcggtggtct tagtgagtaa gaaaaaagaa ccaaaaaaat tgtctcatcc gtcttctgat
    32041 gaaaacaatt tgactccttg gcaaaaggct aaccgaaaat atctggcaga acaagagatg
    32101 aaaaaccaag agccaaaaaa agaagacata acattagata cacccctttc agattctgaa
    32161 gaagaaaaaa cggttcaaga ggaacagcaa gaagaaagcc agtccgagaa aaaaatcgaa
    32221 ttttttgaag agatcaagca aaagaaaaac ggtggaccat ataacggttc ttttttgaac
    32281 cggctgccca atttaaaaag tcaacggcac aaagtactat ttcgtcggtt agctttgatc
    32341 atcactgtat tgggtatacc gctgattttt ttgatctatt atgtttctcc ttatagcaaa
    32401 ttacaagcag ttgcagtatc aggcaataag acagtcaaca gccaagaaat catctctgat
    32461 acaaaattgt cattaggaga aaatgtttgg ggacagtatt ttcatcgatc tacttatatc
    32521 gatcgcctta aaaaagcaca gccaagaatc gaaacagcaa atatacattt caaagggatg
    32581 aatgaattcg atttggatgt aacagaatat aaagagattg ctttgatcgc aaaaaacaat
    32641 caatactacc cagtgattga aaatggaaca gtattagatg aaaaagtagc aaatcctaca
    32701 aaaaatctcc ctatcttgga agagttcaaa gactctgcaa aaatcaaaga attaacaaag
    32761 caatacaatc agttatcatc agaattacaa aaagcaattt ctgaaatcaa gtacacgcca
    32821 agagcaagca ataaaaatct gatccaattg aatatgaatg acggcaatca agttattgta
    32881 aatatcaata atcttgcgaa ccaaatgaaa tattattcgc aagtagccaa agatatggat
    32941 gaaaaaggtg tgatcgacat ggaagttggt atcttctcgc atccttacgg tagcactcaa
    33001 gaaacggaag aatcgggcca atcggaagaa acaactgaaa gtgaagaaaa tgcggatcaa
    33061 acaaacgaat caagtgaaga ggcagaaacg caaaaagcac aaacacctgg atcgtctagc
    33121 acaaacggat catctgattc aaatgattca agtgaaacaa gtcaaataga agataatcca
    33181 agtacaactc cgtcaagttt aaatgaaaat tgataaaaca actttaaaaa gtaagaatgt
    33241 actttctaaa aaccagtaat ttatggtaga attggaagca gtgaatatat ctattaataa
    33301 gtatatttta aaacggacgc tagttgttcg cttgtatatg gaatagtaag taggagggaa
    33361 tcccattcat ggcaaaaaca ggaatgtatg taggccttga tattggaacg acatctgtta
    33421 aagttgtcgt ggctgaatat atcgacagcc aaatgaatat tattggagta ggaaacgcaa
    33481 aatcagaagg gattaaccga ggcattatcg ttgatatcga taaaacggtc caagcgatac
    33541 aacgagcagt acgacaagca gaagaaaaag caggtatcca gatcaaaggc gtaagtgtcg
    33601 gtttgccagc aaacatgctt gaagtagaaa attgccaggg aatgattgca gttaacggag
    33661 attcaaagga aatcaccgat gaagatgtca gaaatgtggc ttcagctgcc cttgttcgtt
    33721 caatacctcc tgaacgtcaa atcgtgtcaa tattgccaca agattttact gtcgatgggt
    33781 tcgagggaat caaagatcct cgtggaatga tcggcgtaag attagaaatg tacggtctgt
    33841 tgtttacagg acctaaaacg atcatccata acatacgtaa atgcgtggaa aatgccggat
    33901 taatcgtcaa cgaaatggtg attactcctt tagcgctgac tgaatcaatt ctttctgacg
    33961 gagaaaaaga ttttggtacg atcgtcattg atatgggtgg cggccaaaca acaacggctg
    34021 ttatgcatga taagcaattg aagtttacca atcttgacca agaaggtggc gaatttgtca
    34081 ctaaagatat ctctattgta ttaaatacgt catttaacaa tgcagaagcg ttgaaaataa
    34141 actacgggga tgcataccca gaacggacat caccagatga agaatttcca gtagatgtga
    34201 ttggtcagtc agaaccagtg aaagtcgatg aacgctactt gtcagaaatt atttcagctc
    34261 gaatggaaca gattttcaac aaagcaaaag atgcattgga ccaaatcgaa gcattagagt
    34321 tgccaggtgg cgtcgtattg acaggcggag ctgctagtct tcctggtgtt gtggacttgg
    34381 cacaagaaat cttcggcgta aatgtaaaat tgtatgttcc aaatcacatg gggctgagaa
    34441 acccggtatt tacaaatgta ataagtatcg tggattattc agcaaacttg agtgaagtgt
    34501 atcaattggc aaaaattgct gttacgggtg aaacctcagc agctcgtcaa atggtagttg
    34561 aacaagaaac aacaaacaca tatgagagct atgaagcacc tgaagaaaca atctacgatg
    34621 agccggaacc aaaagagtcc ggagaaaatg taaaaaataa aatcaagggt ttctttacaa
    34681 atatttttga ttaattcatc ctgggaggaa taagatatgg aattctcaat tgataataat
    34741 atcaatgacg gcgcagtaat caaagtcatc ggagtcggtg gtggcggtgg aaatgctgta
    34801 aaccgaatga ttgaagaaaa cgttaaaggt gttgaattca ttacagccaa cacagacgtg
    34861 caagcattaa aaaattcaaa agctgaaaca gttatccaat taggccccaa atatactcgt
    34921 ggtttaggtg ctggttctca gccagaagtt ggacaaaaag cggcagaaga aagtgaacaa
    34981 tccttacgcg aagctttaga cggtgcagat atgattttca tcactgcagg aatgggtgga
    35041 ggaaccggta caggtgctgc accaatcgtt gcaggtatcg cgaaagaatt gggcgcattg
    35101 actgttggtg tcgtgacacg tccattcact tttgaaggac cgaaacgtgg ccgttttgct
    35161 gcagaaggta tcgctcgttt gaaagaaaat gtggatacat tattaattat ctcaaataac
    35221 cgtttattag aagttgtaga taaaaagaca ccgatgcttg aagctttccg tgaagcagat
    35281 aatgttttac gacaaggtgt acaaggtatc tctgatttga tcacagcgcc aggttacgtt
    35341 aaccttgact ttgctgacgt gaaaacagtg atggaaaacc aaggtacagc attgatgggg
    35401 atcggtgtgg ctagtggaga agatcgcgta gtagaagcaa cgaaaaaagc aatctcctct
    35461 ccattgcttg aaacatctat tgatggagct gaacaagtac ttcttaacat cacaggcggt
    35521 ttggatatga cattgttcga agcacaagat gcttcagata tcgtagcaaa tgcagcaact
    35581 ggcgatgtaa atatcattct aggtacatct atcaatgaag aaatgggcga tgaaatccgt
    35641 gtgacggtca tcgcaacagg tatcgatgaa tcaaaaaagg aacgcaagtc tagccgacca
    35701 gctagacaag cacaaatgca atcacctgct caaaagactg tattagatat ggatcaagct
    35761 aaaccaactt cttcagaaga agaaaacagt tttggcgatt gggatatcag acgtgaacaa
    35821 aatgttcgtc ctagagttga tgattccaat tttgacaata tcgaaaaaaa agaatttgat
    35881 acattcaacc gcgaagaaac aaaatctcat ggcgatgatg aattaaatac gccaccgttt
    35941 ttccgtcgta aaaaataaag gagaggaaga gcacatgatt gctgacaact tgcagaaaat
    36001 caagcaagaa attcaggatt cgtgtgctct tgttcatcgt gatccgaaag aagttacatt
    36061 agtagctgta acaaaatctg ttgaatccgc tcaagctgaa gaattggtta gagctggcgt
    36121 tatgaattgt gcagaaaacc gagtagataa attattagaa aagaaacaag atttatttga
    36181 ttttcctgaa ataaagtggc atttaattgg taatttacag cgcagaaagg taaaattgat
    36241 tgtaaatgaa attgattact ttcatgcgtt ggacagttta agattagcag aagaaatcca
    36301 gaagcggtta gagaaagaat tatcctgttt tattgaagta aatgtttctg gtgaggaatc
    36361 aaaacatgga atttcaccag atgagctttt accgtttgtg gaatctttag ctgcctgcac
    36421 aaaaatcaag gttgttgggt tgatgactat ggcgcctaaa gaagcttctg atgagcaaat
    36481 ccataaagtg tttggtacgc tgaaagaatt gcgtgatctt gttcaagcaa aaggttatgc
    36541 ccatgcacca tgtagtgaat taagtatggg gatgagtcaa gactttcaaa ttgcgattga
    36601 agaaggtgca acatttatcc gtgtaggaac agcgctattc aaagacgaat aaaggaggaa
    36661 caaaaatgcc gcttttaaac agaggagcaa ttgctaattt tttcggatta gctgatgagg
    36721 aagagtacga ataccaagat tatcctgaaa caacaaaaaa ggctgtacag ccaactaaaa
    36781 aaaatacaac acagaatcaa tcaactcatt ctgtatctgc tgcgaatact catgaaaaac
    36841 aaaaaacggc gacttcacgt cctgtaacgc atgaaagtat tcagccggct gaaaagaaaa
    36901 aagtaattga actacatcaa tcacctacaa aaactgtagc gaaagaaaga acagcttcaa
    36961 gaacctctac acaacctaaa gcaaatcttg ctggaaaaat cactgtaatg gaaccaagag
    37021 cttattctga agctatggcg attgctaaac gaatcattgc tggagaagca accttagtga
    37081 attttcattt agtagaagaa aaacaagcga gaagaatcgt tgattttcta acaggaacag
    37141 tttatgcact agatggagat atcaaacgtg ttggagatga gatttttctt tgtacaccga
    37201 ctgggatgga gattgacagt tcaaccgctc aatcttttgc agatgcgaat ttgtttgatc
    37261 tgtaagagga ggaactacga tttatactat tgcactatta cttcatttac ttcaacgggc
    37321 agcctatttc tatagcatta tcttgatggt atatgcattg ctctcttggt ttccaggcgg
    37381 gtatcaatca gggctaggac gattattagc taagatctgc gaaccgtata tcagtttgtt
    37441 cgatcgtctg cctttgagga ttggaccctt ggatttcaca attttagggg caatcctgat
    37501 cttgaactta gccgtacaag gtttagcaca gatcgttata tggataactg tccatttagt
    37561 ttattgattg aagcaacaaa atctttattc tcagaataga taggagggga aaattttgga
    37621 tgcaaatgta taccagcact ttcgggcaga tgaacgtaca tttatcgatt cggtaggcga
    37681 ttggattgaa caggttcaag gacaatatgc accctatctg accgaatttc ttgacccaag
    37741 acaatcctat attttagaaa cactgattcg acaaagcagt gatttgcgtt tcatgtttta
    37801 tggcggatat gaacaggcag aaagaaaaag atgtttgatt ttccccgatt attacgaacc
    37861 tgtagaggaa gattttgaaa cagcattgta tgaaatccat tatcctagca aatttgccag
    37921 cctaagtcat gggaaaatcc ttggaacttt agtgggaacg gggatcaaac gctcttactt
    37981 tggcgatatc atctcggacg gtgatcgctg gcaagtattt attgcaaatg aggtggatca
    38041 ttttgttgct gcacaagtaa caaagattgg aaaggttgct gtacgcttgg aaccaatcaa
    38101 atacacagaa atgattatgc cgaaagatag ctggacacaa gaaagaggaa cagttagttc
    38161 catgcgacta gacagtgtga tctctgagat ttataatatt tccagacagc ggtccaagca
    38221 gctgatcgaa gctggtaaag taaaagtgaa ctggacagaa aatacaagac ctgattttgt
    38281 acttgaacta ttagatatta tttcagtcag aggttatggc agagtccaga tccaagaact
    38341 tgaggggaag acgaaaaaag aaaagtacag ggtactgttc ggtgtattac gtaaataaaa
    38401 taaaaaggtg gtttactcat ggctttaact ccattagata tccaaaataa gacattcccg
    38461 acaaaaatgc ggggatataa tcaagacgaa gtagatgatt tcttagattt agttgttcgt
    38521 gactatgagg aattgactca aagaaatcga gaattagaaa aagcagtcaa acattctgaa
    38581 gaaaaacttg agtacttcaa tgaattaaaa gatgctttga accaatcaat catcgtagct
    38641 caagatacgg ctgataaagt aaaaacaagt gcaagcaagg aatccgaagt gatcgttact
    38701 tctgcacaaa acaaagcaga tgagttagtt gcgaacgctg aaaaacgtgc acatcaatta
    38761 acaactgatg cagaagaaaa agcaagaaaa atcttgacag atgcaacaga aaaagcaaga
    38821 cagcttgcga cagaaactga agatcttaag aaaaaaacac gagtattcca tcaacgtatc
    38881 agcttgatgc ttgagtctca attagaacaa gtgaaaagtc cggaatggga tgaaatttta
    38941 caaccattct ccagctacgt gactgacagc catgaagtga tcaaagaagt tttagcaaaa
    39001 cagcttgaca atgaaaatga tactgatgta aactcagaca caggagtcat agaagcacct
    39061 atgacggcat ttgatacaca ggctattgat atctcgatcg tgcctggtga aaatgaaaac
    39121 gagtagaaca gaaaagcact ttgttattct taaagcgagc cgatgagagt ggaagttcgg
    39181 taagacactg catggtgaaa gatcctctac ttgagacctg cttttccgaa attagagtaa
    39241 gaagcagcgg ctgacctcgt tattggtcac agagagtttg cactagatag atgcaactaa
    39301 atttgggtgg taccacggca tgttcgtccc ttgcggctga acatgctttt ttgtgtccgg
    39361 aaaacaaata aaggagtgta tggttgaatg aaaatgaaag aaaccttgca attaggaaaa
    39421 acaaaattcc ctatgcgtgg taatttgcca aaccgagaag gcgagtggca aaaagaatgg
    39481 gaagaaaatc gaatctacca aaaaagacaa gagttgaacg aaggaaaacc tagctttgtt
    39541 cttcatgatg gacctccata tgccaatggt aatatccatt taggacattc attgaataaa
    39601 atcagtaaag acattatcat tcgttcaaaa tcaatgtctg gctatcgtgc accatatgtt
    39661 ccaggatggg atacacatgg attgccgatt gaacaagtat tggctaataa aggcgtgaaa
    39721 cgtaaagaaa tgtccatggc agaatacttg gaaaaatgtc gtgaatatgc actttcccaa
    39781 gtagataagc aacgagcaga tttcaaacgc ctaggagttg caggagattg ggaacatcct
    39841 tatgttacat tagatccttc ttatgaagct gcacaagtac gcgtatttgg taaaatggct
    39901 gaaaaaggct atatttacaa aggattgaaa ccaatttact ggtctccgtc aagtgagtct
    39961 tctttagcgg aagctgaaat tgaatataaa gatgtaaaat ctccatctat ttttgtagct
    40021 ttcaatgtca aagacggcaa agatattctt gatgaagata cagcttttgt catttggacg
    40081 acaacaccat ggacattgcc agcaaaccaa ggtattgctg taaatccaaa atttacgtat
    40141 gtattggtgg aagccgatgg ccgtaagttt gtcgtagcga aagatttgct agaaacagtc
    40201 caatcagaaa tcggttggga aaatgtaaca gttctaaaag aatttgctgg acaagaaatg
    40261 gaatatatga ctgcaagtca tccattctat gaacgtgaat cacttgtgat tttaggcgat
    40321 catgttactt tagacgctgg tactggatta gtccatactg ctccaggaca tggggaagat
    40381 gactatatcg ctggtagcaa atataaacta tctgtagtgt cacctgtaga ctcaaaagga
    40441 ttgtttacag aagaagcacc tggatttgaa ggtatctttt atgacaaagc aaatcctatg
    40501 atcactgatc tattaaaaga aaaaggagct ttgctgaagc tagatttctt tactcatagt
    40561 tatcctcacg attggcggac gaaaaagcct gtgatctatc gggcaactcc acaatggttt
    40621 gcatctatcg ataaattccg tcagaatatt ttggatgaag tagaaaaagt agagtgggtt
    40681 atcccatggg gtaaaacacg tttgtataat atgatccgtg accgcggcga ttgggtaatt
    40741 tcccgtcagc gtgcatgggg agtaccactt ccgattttct atgctgaaaa tggagaagca
    40801 atcatcacac cagaaacaat cgaacatgtg gcaaaattat ttgctgaaca tggatcaatt
    40861 atctggtttg aaaaagaagc gaaagaactt cttcctgaag gatttaccca cccaggttct
    40921 cctaatggcg aatttacaaa agaaaaagat atcatggatg tctggtttga ttctggttct
    40981 tctcatgaag ctgttttacg tcagcgacca gaattatcat tcccagcaga tatgtattta
    41041 gaaggatcag accaatatcg tggctggttc aactcaagta tcacgactag tgtggctatc
    41101 aatggtgtag caccatacaa atcagttatt tctcaaggat ttgctttaga tggtgaaggc
    41161 cgtaagatga gtaaatcttt aggaaacatc attgcaccag aaaaagtgat caaacaattt
    41221 ggtgcagata tccttcgctt atgggtatct agtgtagatt atgaagcaga tgttcgtgtt
    41281 tctatggata tcttaagtca agtggcagaa gtatatcgta aaatcagaaa tacgatgcgt
    41341 ttcttattag cgaatacaga agatttcgat cctaaaaaag atactgtttc gtacaatgat
    41401 ttacgttctg tagacaaata tatgaccgtt cgattgaacc aagtaatcaa agaaatccga
    41461 gaagaagggt acgacaaata taacttcatg catatttacc gtacagttat gaacttcttg
    41521 acggttgatc tatcgtcatt ctacctggat tttgctaaag atgtagttta tattgaagca
    41581 gaagatgatt atcaacgtcg ttgcatgcaa actgttttct atcaaacagc tgtagctttg
    41641 acaaaattat tgactcctat cattccgcat acagcagaag aaatctggtc attcctgaaa
    41701 gaagaagagg agtacgttca gttaagcgag tttcctggtt atgaagagtt tgcaaaccaa
    41761 gaagaattga tggatacctg gactgctttc atggacttcc gtgataatgt cttaaaagca
    41821 ttggaagaag caagaaacag caaattgatt ggtaaatctt tggaagcaaa actaactgtt
    41881 tatccaaaac aacaagttcg tgaaatgtta aaagctttgg atgcagatat tgcacaatta
    41941 ttgatcgttt caccagacta ctttgaagtt atggcagcag atgaacaagt gccagataac
    42001 gctatggtat ttgatgatgt tgctattaca gtggaaaaag cagacgggga aacttgcgat
    42061 cgctgtcgcc aagttcgtaa agatgtagga gtagatgaaa aacttcctca tctatgcggt
    42121 cgttgtgcaa aaatcgttga agacttctat cctgaagctg tagctgaagg attcgaagaa
    42181 aagtaaaagg gaaaaggggg tgtgacatgt tctttgtcac accccctttt gttatcaatc
    42241 gtttaatttt ccacgttcac gataccagtt atctggttgc cagatccatt cgaatccgtc
    42301 tttttcaagt agttcgaaag ctgctttagg tcccattgat ccagctttgt agttgggaaa
    42361 atccggttgt gtttggtccc aagcttttcg aatgacatcc acgatatgcc aagattgagc
    42421 gacttcttcc caatgagaga agttcgttcc atcaccattc aacgcatcta atagtaattt
    42481 ttcgtaagct tctgggctat tttcaaccat ttctgcacta tttctaaatt ccaatttgat
    42541 tggttccgtt tcaaatcctt gccctacttc tttcccattc aaggataaag aaaatccttc
    42601 agttggctga atatagatcg ttagaacatt aggtggaagt gtcgtatcgt cacatggttc
    42661 atcgacagat gttttgaata cattaacagg aacttgtttg aatacgatgt tgatccgagt
    42721 ccctttttca gtcaaacgtt tgcctgtacg tacatagaaa ggaacacctg accaacggaa
    42781 gttatcgata gtgaatttgc ctgcgacgaa tgtttcagtc tctgattgag catccacttt
    42841 gtcttcttcg cgatagccct tgaattgtac accatccaat tcaccttgag catattgccc
    42901 gcgaacgaag ttttctaaca cttcttcttc gttataaatg cggatagctt tcaatgcttt
    42961 gatcttttct gtacggattt ctttttcgga aaatgctact ggcggttcca ttgcaagtaa
    43021 tgctacaacc tgtaaaatat gattttgcac catgtcttta agtgcgccac tatgatcgta
    43081 gtagcccccg cgatcttcta caccgaggtt ttcgccaaaa gtaatttgga tattgtcgat
    43141 atagcgattg ttccattgag cctcaaaaat attattggca aaacggatag ctgagatgtt
    43201 ttggatcatt tcttttccta aataatgatc aatcctgaaa atatcttgtt ctgggaatac
    43261 ttctctgatt tgctggttca attcaaaagc agactggtaa tcagaaccga acggtttttc
    43321 tatgatcaaa cgattgaagc cattttttgt cataatattt tgtgatttca aatgagaaac
    43381 gatcgttcca aaaaattgag gtgccatagc caaataatag acacggttac cgtttaattg
    43441 atagtgtcca tctaatcggt cagacaattc ttttaatgtc tgataatgcg ttgaatcatt
    43501 tacatcatgg gattgatagt aaaaatggct tgcaaaggta gttgcttctt catctgaagg
    43561 attcaatgca cggattgttt ctttgacaac ttcacggtag tgctcatcgc tccagggacg
    43621 gcgagcggtt ccgattacag caaaatgctc gcctaaattt ccttttctgt aaaggcggaa
    43681 caaagacggg tacaatttac gctgggctag gtcacctgta ccgccgaata tcgtaaacaa
    43741 tacatttttt tcattagaca tgtggataca ctcctttata ttttatcgac aaaaatcgtg
    43801 ctggccgcct taaagctgac ggggattttc tttctatcat tttggatagt gatcggtcct
    43861 tcataagctg cgatgtcaac gatctcatat tcttcgttga tattcaggtc aatagtgact
    43921 aagtaatcca acaattcttt ttcatcaagc actcgtgcga tacgcacttt tgtaccgaca
    43981 ggataggact ccaatgtttg tcggcgttct tcatggacaa cttcctcttt tttaggaatc
    44041 gatcctccat gaggacaatg ttcaggatga ttcaaatagt tttctaaatg atctgcaaga
    44101 tgttccgaag tcacatgttc caatacttca gcatcatcat ggacttcatt ccagctatag
    44161 tctaaatgtt caactaaaaa aacttcccat aagcgatgtt tgcgaatcag actgctagct
    44221 ttttgcagtc cgcttgcagt caattgtaca ccttgataag gggaatgttc tacaagctct
    44281 tctttcacaa gtttagaaat catttcactg acagatgcag ctgagacatc tagactagat
    44341 acgatttgtt tattgttgac tttcgttgta tctccaccta gttctaaaat gattttcaaa
    44401 taatcttctc gatttggtgt catattcgat catcctttca tggtaaaaaa ccatcattag
    44461 taagtgtaac aaaaaaaacg ttaattgact atttttctaa ataaaaaaca aaggattttt
    44521 agacgttttt acaacaaaaa acgaaagatg atagagaaga ctcattcttt cgtttataaa
    44581 ggatatatat atacattggg agggatctat ttttcagata acaacttata tgaagtgtct
    44641 gcagattcgt cataaagagt ttgttcggga taagaaaaga taagataaaa accatactga
    44701 tcacgtacga ctaaacgata ttcatctatt tctaccacag atgtgccaag agactgaccg
    44761 ttgatcaaaa acgtgtaatc agatgtaatc tgtaattgtt gtttttgctg gctatcacta
    44821 aagaaccatg taccttgata ctttgagagt ccttctgact tttccgcttg ttttttcttt
    44881 ttcaagtaaa taaaacttga gagaacggta atgagtgaac caagaaaata gatcattttt
    44941 tttatcacca aatcactcct ttatgagaaa ataatcgcat agacatattc tttcttcttt
    45001 atttcattgt accgaataaa agctaaaatt tctctaagac tttcgactgg tttttttact
    45061 gtttttctac aaattatgat aggatacata gtaggaagaa aggtgacata atttgaagta
    45121 tcagcaagtg gaaatagctt tttttattga ccgcccgaat cggtttatag cacattgtat
    45181 gaaaaaagac ggagaaataa ttattgcgca tgtcaaaaat acaggtagag gaaaagaggt
    45241 cctgatacca ggcgctgaag tggctattgt atttgctcct ggacctaaac ggaaaaccgc
    45301 ctatgatctg attgctgtaa aaaagaaggg tgactggttt aatatcgata gtcaattgcc
    45361 taatcggctg gcaattgatg gtattttaga cggcacgatc cttttaccag gattaactgg
    45421 tccatttacg gtatacaagc gtgaagtaac ttatcttcac tccaaatttg atatttattt
    45481 agagacggtg gtcggacaaa aagcatttgt tgaagtcaaa ggtatgacac ttgaaaataa
    45541 agcgattggt gcttttcctg atgcgcccac actcagagga ttgaaacata taggagaatt
    45601 aacgtatgcc gcacaagatg gttatgccgc ttatgtcttg tttattgctc agttcgaaca
    45661 tcttcatctg gcaacgatcc atgaagaaat gcaaccagca ctagctgata tggttcgaca
    45721 tgcgcagcaa agcggagttc aaatcctcgc ctataattgt caagtatcgg cagatgaggt
    45781 aactgtcaag caggccattc catttgatgt agatatccct tttgaagatc ctatacaata
    45841 gaaagaaggt aaaataatga tcaacttagg tattatcgga acaaattgga ttactcatca
    45901 atttgtccaa gcagctttaa gcacaaaaaa atatgaattg acagcggtat attctagaca
    45961 tttggaaaaa gcacaggaat ttggttctca ttatgaaggg gatatcgaat tcgcaacaga
    46021 tttgaagact tttttcaata ttactcatat ggacaccatt tatattgctt ctccgaatag
    46081 tcttcacttt agtcaagcta agcaagcaat tttggcagga aaaaatgtga tagttgaaaa
    46141 gccagctttt tcgacgccaa aagaaatgga tgaaatcatc catttggcaa atgaacacaa
    46201 tgtgtatttt tttgaagcag caagaaatat ccatgaatca ggttttaaaa agattgccga
    46261 ttacttacca ttaaaagacg agataatcgg tgcaaatttc agctatatga aatattcttc
    46321 gcgctatgac caagtattag atggagaaga accgaatatc ttctcgactc atttctcagg
    46381 tggtgcattg atggatttag gtgtttacct tgtatatgca gctgttgctt ggtttggaat
    46441 gccaaaagaa gtccattatt tcccaagaaa gatttctact ggtgtagatg gtcttggatg
    46501 ggggatctta cgttatgaga attttgatgt atcgatccag ccaggtaaaa tcggtgattc
    46561 ttatttaccg tcagagattt attttgactc aggaacgcta gtgatgaatg gagtcaatgc
    46621 aattgaacaa gcacaatttc atgatcgcgc gcataaagaa atcattgatt tggcggtaac
    46681 agctgcagaa aatccaatgg cagatgaagc agaggatttt gccaatgtca tggctcatcc
    46741 gaaagatcca gcttggggat tgttgtatga agagtggatc gagctagcta gaaatgtgaa
    46801 ccaagtgatt tatgatttaa gaaaaaatgg cggcatcaaa ttcgatgcag ataatgagga
    46861 agatttttaa tgaacgaatt tgtacaagta tttcccgaaa attggcagaa aaaatatgag
    46921 gataaagggt ttatctcacc ttctcttatt caacgagcag tttttcagcc actaagtaat
    46981 aaacaaagta tagtagcggt ttctcctaca ggttcaggta aaacactggc ttatctttgg
    47041 cctctactac taaacgtgga accaggtgaa gcaagtgcgt tggtcatttt tgcttcttct
    47101 caagaactag ctattcaagt agcagatgtt gcacgtgaat ggggaaaaga caaagagttg
    47161 aaagtccaat ctttggtggg cggagccaac gtcaaacgtc agattgaggg tttgaaggaa
    47221 aaaccagaaa tcttgattgg tacaccagga agaatattgg aattgatgaa agcaaaaaaa
    47281 ataaaagcac atcaagtgaa aacaatggta tttgatgaag cagaccagct atttgacgct
    47341 gggaacagcc aaatcattga tcaaattctt catcaagctc caacagagta tcagctagct
    47401 tttttttcag cgacagcaga tcgttccctt gaaagcattg aaaaaatcac tgggaaaacg
    47461 tttgagacaa ttgacgtgac agcagaggac gattctcgaa aaggactgag acattacttt
    47521 ttacgtgtac cgatacgaaa gaaagatgac tacttgagac gtctcacgca tatagaagat
    47581 tttcatggtc tgattttctt taatcaactg actgaattag gcgtaatgga agaaaaattg
    47641 ctgtatagag gtgtaccggt aggaagtctg gcctctgatc agaacaagct actccgaaaa
    47701 gcagcgctag aacaattcaa aaagaaaatg gtcagagcac ttttgaccac agatgtggcg
    47761 gctagaggtt tagatattac aggtcttcct tatgtagtga atgcagaagt tccgttaagt
    47821 gaagaagctt atttgcatcg ttcgggaaga actggtcgaa tgggtaatga aggaatagta
    47881 attacactcg tacaagataa taatctaaga gatttaaaac ggcttttacg tccatcaaat
    47941 ataacacttg aagagatttt tttatacgga ggtaagctgc aaactgagca gccaaccaaa
    48001 gaagatgcag ctcctgcagt aaataaaaag tatgcgaaaa ctttttctgg aaaggagcag
    48061 aacccagaat ataacaaaga aaaaataaga aaaaaagtta aaaataaatc aaaaaaagag
    48121 agaaataaag gagcaaggcg caaataagcg cctttttatg ctatgattat gaaaacggga
    48181 acaaaattgg ttgccagagg aggggttatg tgaaagaacg tcaagaagag atcttgcagc
    48241 tattgacaga aaaccaacaa ggattgacag caagtgatgt agctgagcgc ttaactatcg
    48301 atcgaagcaa tgcaagccga tatttaagtg aactatacaa ggcccatcat attgtaaaaa
    48361 ccgctggccg accagtcgtt tactctttgc caacggaaaa gtcaaaatct gatgaagtgc
    48421 atgtcgactc ttctacgcaa gtgacttttg aaacactcgt tggagaaaat gattctttaa
    48481 aagtcagcat acagcaggca aaagctgcga ttctttatcc accgcggggg ttgcatacga
    48541 ttatttttgg agaaactggt acagggaagt cgatgtttgc tgaatgtatg tatcattttg
    48601 caatcgattc agagatgctt tctgcagatg cgccatttgt ttctttcaat tgtgcggatt
    48661 atgctcaaaa tccgcaactg ctctttggac acatctttgg gatcaaaaaa ggggcttaca
    48721 caggagcagc tcaagatagt cccggtctaa tagccaaagc agacggcggt atattgtttt
    48781 tagatgagat ccaccgttta ccgccggaag ggcaggaaat gctgtttact ttcattgata
    48841 aaggtattta ccgtccgctt ggagaaagtg cacaagtaca tgaagcatct gttcagatca
    48901 ttggggcgac gactgaatct tcagaaagtt tcttatctac gttcaatcga cggattccta
    48961 tggcaatcac cttgccgaat cttgcttcac gttcactgga tgagcgttat gaaatcatct
    49021 ctctttttat caaacaagaa gcgaatcgtt tgaatcaacg tatcgatatc gaaaaagaag
    49081 cgattcttgc cttcatgctt tatgatgcgg aaggaaatat cggtcaagtg aaacgagact
    49141 tgaaactagt ctgtgcaaaa tcttttttac attaccgtac tcatcatgag aaaaagctaa
    49201 tcattcgaaa agaagaactt tcccttcaag tacaaaaagg attactgaaa atcaaggaaa
    49261 taccggaacg tctcgaccga ttcatggaca gcaaaagtca gtatttgaca tttgaaccag
    49321 gatttgctga tgttgtctgg tcacaagatc cagaacgaaa catgcaggtc tataacgata
    49381 ttgaggaaaa agtcacttct ctttccgaaa ccggtgtgga gaacattgat ctagagaccc
    49441 tcatttcaaa agatgtggat gcttatttcc agacatatgt caaagaattg actaaaagtt
    49501 cgattcccaa agatcttttg ccagatgaaa tctggcggtt aaccaatcaa ttgtatgatg
    49561 tggctgaaaa acggttagac cgtatttata atgaaaaagc tcgttttgct tttgctttgc
    49621 atctgcaaag tacattggat cgtgtgagag aaggtcatat gatcgtccac ccagatttga
    49681 ataacgtacg gaaaaatttt aagagggaat tccaggtagc aatcgatctt tcaacgatca
    49741 ttgaagaaga agaacaagtt gagattcctt ttgatgaaat cggctttatt agtatgtttc
    49801 tttctatcaa tctaggagaa agtgagcctg ttaaagaaaa caaagtagat gttctcatat
    49861 tgatgcacgg cagacagact gcttcaagca tgttggagat ggcacaagaa ctattaggaa
    49921 caaaagtagg gaaagctttt aatatgccac tggttatgga agttcaaaca atgtatgaag
    49981 aagtgttaca atatgtcaaa aactatcaag agcatttgac gaatggccta ctcttgttaa
    50041 cagatatggg atcattaaac accttcagtg atttgattta tgaagagact ggcattcgga
    50101 cgaaagctat cacgatgaca agtaccatga ttgtgataga agcgatacgg atggcaagtg
    50161 ttggaagaag cttagaagat atttatcaaa atatccagct ttcctttgaa tcgatcgtac
    50221 gtgatcagtt caaagcggaa aagtctgaaa ctttacagcg taaaaaagcc gtaatcgtga
    50281 catgctttac tggtgaagga gtagctgcca aattatatca gcgtattatg ccagtgatta
    50341 atcaaaataa ggtagaactg atccagatgc agtttttaga acgtgaatca ttcaaaaaac
    50401 acatcgatgc cttattggaa gaatatgaga tcaaagcaat tgcgggaaca gttgatgttg
    50461 attatcaaaa tatcccattt ttttcagcct atgacgtttt tgatgatgaa aaactaaata
    50521 ttttaaagcg tatagctgat gatgagatcc cgacagctaa aattgtcgat tcacttgctg
    50581 gatcattaag cgatgtcttt tctattgatg aactgatccg ttcattgcaa aagacagttc
    50641 agcagatcca gaccgatttg tcgattatcg tggaacctgg agtagatact ggaatcgtta
    50701 tccatttagc cttcatgtta gacggattga tcaaacaaga aagccatcgg caatttgaga
    50761 aactgtctat tttctcaaaa atttatcgtt tggaaatgga tatcgttcgg gcaaacttga
    50821 tggcactaga acgaaaatat caggtaaaaa ttccagaaga tgatatcgca tttcttacac
    50881 aaatgtttct tgaaaataaa ataaaaaaat gaacacacta atcatactgt ttacacacta
    50941 aacatctgtg tgcgcactat aaaaaagagc taaaaagcat gaaaacgcta tttcagctct
    51001 tttttttatt ggcatgcttc ttgcgttata taaaagtgta aaaaaataaa aggagtgtta
    51061 aaaatggcaa aaaaaacaat catgttagtt tgttcagcag ggatgagtac gagtttattg
    51121 gtcacaaaaa tgcaaaaagc agcagaagaa aaagggatgg aagccgatat ttttgcggtc
    51181 tctgcctcag atgcagataa taatttagaa tctaagaatg tcgatgtatt attattaggt
    51241 cctcaagtac gtttcatgaa agctcaattt gaacaaaaac ttgcgcctaa aggtattcca
    51301 ttagatgtca tcaatatgca agactatggc atgatgaacg gagaaaaagt tcttgcacaa
    51361 gcagaaaatc taatgaaata aatcaagtat gcagttgggg gtataacaac gtggaagatc
    51421 aacaaaatct agaagccatc atggggttaa tcatgtttgg cggtaatgca aagagcgatg
    51481 caatggaagc gattgcggct gctaaaatcg gtgattttga gttagcggat aggaaaatcg
    51541 ctgatgcaga agaatcactt atacaagcgc atcatgcaca aacagacatg ttgacacaag
    51601 aagcacaagg aaatcatatg caagtgacat tattgactgt tcacagtcaa gatcacttaa
    51661 tgacatctat tgcgtttact gatttagcaa aagaaatcat cgaactttat cgtcgcgtat
    51721 acagcgaata aatacaactt cttttttgaa cggaagaaga aaaatttttg aacggatttt
    51781 ttattttgtt ataaggagaa ctctctttat ataaaaaact tataggagga agtaaaaaat
    51841 gaacggacta tcaagttgga tggagaaata catcctgccg gttgccgcaa aaatcggagc
    51901 gcaaaaacat ttagttgctt tgcgtgatgc ttttatcggc atactgcccg caacaatggc
    51961 gggatcagtc gctgtaatga tcaatgcaat tattcgtgat ttaccgcaac agtttaacag
    52021 tacctatgct gacagtttag cagcagacaa aggaatcttt gccgtattga atgtcatcat
    52081 cggaatcaat ggttttgtct ggaacggtac actagcaatc gccggattga tctttgcctt
    52141 ttcttggggg tataatcttg cccgagctta tggagtaaat gatctagctg gggggatcgt
    52201 tggtttagct accttgattc aaggtatttc ctttggtcca gcattatcag cagcattaga
    52261 tgtgaatgtt ccttcaaatg tcgcagatgc aatcaatagt tctgagattg gtgcaacgat
    52321 tgcagatggc acactgtcag ttggattatg gggttggcta aaactagatc atttgaatgg
    52381 aaacgcttat tttacagtta tgatcatggg agctatttca gtcattattt tttgtaaatt
    52441 gatgcttgcc aacattacga tcaaaatgcc tgattcagta ccaccagcag tatctaaagc
    52501 atttgcagcc attttaccag cgacgatcgc tttatacgtc attgctatta tcaattatat
    52561 cgtaggtcgt gtagctgatg ggcaactgat cattgatttg gtgcaaaaat atattgcaga
    52621 accattccta ggattatctc aagggttggg agcagtattg atcgtcacag tatttgttca
    52681 agtattctgg ttctttggta ttcatggatc aaatgtattg gcaccagtgc tagagggaat
    52741 ctggggacaa gcacaactaa tcaatattga tattttccaa aaaggttata acggaaaaac
    52801 tggtacacca gccgtgttag atgcaatcga agatggaaaa gcttatatgt gggtccgcgg
    52861 atcgttcgat gcttttgcat ggtttggcgg atcaggcgga acgatcgtct tactgatagc
    52921 tatcttgatt ttctctaaac gtgcagatta tctaacagta gctaaattat ccattgggcc
    52981 tggtatcttc aatatcaacg aaccagtgat gtttggtctg ccaatcgtat tgaatgcaat
    53041 catgtttatc ccattcttga ttgctccagt agtagcaaca gcaattggat ggacagctac
    53101 ttatcttggc ctagtcgctc cggtatcgca gcaagtcaca tgggtagtac cgccgttctt
    53161 attgtcattc ttagcaacag gagcggattg gcgggcaccg atcgtaacat tagtatgtat
    53221 ggtcgtgact ttcttgattt gggcaccatt tgtcatctct gcaaacaaaa tggaccctgc
    53281 cgcaggcgaa caacaataag atgaacgtga ggagcgggac gctttaagtt tcgttcctca
    53341 taatgaattt tcgaggagga actgaaatga ttacaattgc cagtgcaatg caacaagatg
    53401 aaatcaaaga attgttagaa ggatacaatg aagaaggaat gacttttaca tttaaagaaa
    53461 aacaaggaat caagctgttc tttgaaacaa gtgcagaaga tccggaagtt gcggctaaaa
    53521 aagcaaagga actaatcaaa gcacagcctt ggggaacagt cctttatttt caatcaacag
    53581 ctgtttagaa aatggtttaa aaagatagga tggttgagat gataaaaaac ggtttatttt
    53641 tatgtagtat tggttctttg atcgtgttgt atagtttgaa tccacattcg caaaggtatg
    53701 atttgtatag tatggtcaca ggtctttttc taacaggatt aggaatctat ttcttcatga
    53761 aggggaaaaa aagagaagaa gcaaaggaga aaaataacta atggaaatca cgaaaaaatt
    53821 aaatattcca gcatcgtttt tttacgataa agttatggac tctgtccttt tcgatgtacg
    53881 taaagcgacc ggcaaatcag taactagaaa acagctgaaa aatttggagt acgtcaaaca
    53941 attctcgcaa aataaccggg ctcgcataaa aatcgaagaa gtcattgaaa accagtctta
    54001 taagtttcgt acatcgacaa cgaagaatga attcgtcgtt cattatcaaa tcaaaccatt
    54061 ggacgattcg acctgtgagg ttcattacac agaaaaaatg gagtcttatg gcatgcttca
    54121 aaagttgaat gatatgcttt taggaacaat cttgatgtat tttaaacgga gacgtttcaa
    54181 aaaaatgcta gatatgatcg aagcaacgta ttaaatcaat gaaacatggt actatttagt
    54241 tattgaaaaa tgaagtaagc tagaaggaat ttttcatagg aagatagatc tttcctgcga
    54301 atcctcacta gcttttttgt aggaaggggc agcaaaatga caaacaaagt aagagagcta
    54361 ggtgtatctt cgattgagga aatgtttgat ttagccactt atgcatttaa tggggcagat
    54421 acacctgaaa ggcgagaacg ttttcgtaca cttgcggaga attcttggaa ttacggattt
    54481 tttgatgagg aggatcggct aacaagtcaa gtcatggcga ccccttttcc agtgaatttt
    54541 tacggacaag agtacctaat ggccggcatt ggctatgttg cttcttatcc agaagcaagg
    54601 ggacaaggcg ggatcaatca gatcatggaa aagatccttg aagattgccg tgatcgtaaa
    54661 gtaagcttat cttatctggc gccattctcc tatcccttct atcggcgcta tggctatgaa
    54721 caatcatttg ataaaatcag ttatcaacta aacagtcgtg atgtgccgtt tatcaaaaaa
    54781 aaatctggaa aaataaagcg tatggatttt gaagatgcaa aagctgcaat cagaagaatt
    54841 tatgaacaga tgccggaaaa ccaacgagct ggtctgaagc gcgaagactg gtggtatacg
    54901 tataaattca agcaaaaagg caattaccag tttgctttgc attttgatga taatgaggaa
    54961 gcaacgggat atatcgttta tcagcttgca acgtcttcct ttattattgc ggagtgggga
    55021 tttttggatc atgatgcttt ttgcagcctt gttcgcttcg taagttctca caatggtgct
    55081 tttgaaacat ttgaatattc atgcggctac ggcggtaatg atcaaaatta tctattagaa
    55141 aatccatttg cttctgtaat gatcacacct tatatgatgg cgaggatcgt agatatttct
    55201 ttgtttttgg aaaattatcc atttaaaaag agacaagctg catttgccct acaaatagaa
    55261 gaagatcatt atgcgaaatg gaatgaagga atcgtggaag taacaatcga aaatggaaaa
    55321 aatcatctct caaaagtaga acaaacaaaa ctcccaatcg ttcgaggaag tatccaacat
    55381 atcacgcagc tattattagg gtatcgtaaa gtggaagagt tggtattcca agaaagaata
    55441 caggtgacaa aagaatatga agaaacgtta agctcaatct tgccacagca acagccaatt
    55501 cttaatgact atttttgata aaaaacgggt gatgacaata tttttgtcac cacccttttg
    55561 tttttcattt ggcatttgaa ggaaaatgtt aaagtaaatc ctcttttttc gtaaatttga
    55621 attttttgtt ttcttttgtt ttagggtttt cttttttgtg gtcttggatt gcttctttcg
    55681 taatcttttc ccgatttttt ttagatgaat ctaagcgttc tgcgtatact ttttcttttg
    55741 gcttatcatt cattggaaag gacctcccta cattatttca ttctacctct agtttatcat
    55801 ctgttaagga ctagtggaaa cgttttgcct aacttataag ctgatttttt tagcagataa
    55861 gcttgcaagt aaaaaacaaa caagctacaa ttgatttatt gaaattgttc ctgtagctca
    55921 gtaggataga gcaatcgcct cctaagcgat aggtcgctgg ttcaattcca gtcaggaacg
    55981 tataaataac ccctgtatcc tttgcggtac aggggtttgt tttgtatttg tgccaaaaat
    56041 gtgccaaact agttatcatt tttatataaa ctatcgaaca cagtattgat tttttcttta
    56101 tcctgatctt caagctctcg aacaatatga agataagtag acattgtagt ttctaaactg
    56161 ctatgtccta aacgtttcga tacgctaagt atatttactc cttgataaag taaaatagat
    56221 gcatgtgtat gccttagtcc atgcaaagta aattgctttt caatccctaa ttcttttaat
    56281 tttttgcgca aatatttgct gacggcgttt gatgaaacta atccattttt taagttgaaa
    56341 aaaacaaaat tatgagggtt tttgatttca aaattctcga ataattcttt ttgattgatt
    56401 ttaaactttt ttaagagatc aatcgtatgt ttatcaatgg aaattttcct atttgaagtt
    56461 tcgttttttg tttttcccca ttcatttaat ttataattcc atgttttatt aatagtgatg
    56521 atttgatctt cgaaatcgat atcttcccat gttaatccta gaagttcagc aaatcgcatt
    56581 ccagtggcac cagcaactaa cacgagcata ggagaagagt actgcgcaga aaggttttct
    56641 tctacgagtt tcattaaaga tttaaattga tcataatcta aatatttatc ttcttttggc
    56701 ttcaatgaat cttttccttt gattactgct tttctagttg gatcaaacgg aattaatcct
    56761 tcttctacgg catctttcaa cgacgctcta atatggttat taaacttaat aacggtagat
    56821 tttacatggt ctttagcata cttatttaaa aagcgttgat atcccactct atctaaatca
    56881 gaaatcaata ccgctggcat atatttcttt atgttcatta acgtatcttc gtattttcta
    56941 taagtgatag gagatactgt tccttcttta taaagttgca tccaatcctc aaagtaatct
    57001 gataataata gatttttgcg atccccttta aggcctttgt tcaagttata ttctaattcg
    57061 ttggcggcat cttttgcttc tccttttgtc ttaaatcctg attttcttat cttcgtgtat
    57121 tttccgtcat cttttttgta tgaaatttcg tattgccaac tatttccacg tttgactaat
    57181 cttgccataa ttgaatcagc tctctttctc tgatacaata ggaactataa agaagcccat
    57241 tgtttgggtt ttattatttt ttgcacatcc tttttgcttg ccggcgcaag gatgtgctat
    57301 ttgtcgtttt aatggtataa ttggatgtgt attagatcat ccaatcagag gtgtttatta
    57361 tgattaaagt gatttttaaa agaataactg aacttccaga gtttagatta tttgttgatt
    57421 attggtatgt ctggtttttt attgttgcat tgctgatagg tctagatgtc atattagaaa
    57481 gaaaacttaa gtaagagttg agttaataaa ttgaattcct aaatgagata ttttgtagcc
    57541 catattttgt ttgccgacat cacctaatac tatggagcta atcgtttttt ctaacagacc
    57601 aaaatcagat aatctattta agctaccatc tattagctct tgtgaatagc cagacatgct
    57661 gatatttcca gtgaaatttt cgtttccacg actcattaag catgctaaca attgaatctc
    57721 aatcgatgtt aattgattca gtacaagaag ataatactcc tcgttatccc atgaagcgtt
    57781 gttaattcga agtaaacaat tcttataaag atttttatac atatctattt tattttgtgc
    57841 ctttgatttt tctacctcgt catttatccc ttcgaatatt ccaatgagtt ggtccttgtt
    57901 ctctaagttg aaaacatctt ctggaatttg atcgcgaatg ttttctaatg attcgtttaa
    57961 atttttgtag aatttctcga tgcgtttgaa acgcttctcg tttttagacc caaaataaag
    58021 tgactgcaca acgccaccaa tataaggaat tgctccaata ccgccttcaa ctattaattc
    58081 aagatattct tttttggtta gtttttcatt gctattatcc atagttacct cctattttgt
    58141 catttccttt acaagcattg tgactcctga tggcactctt ttgtataggt tttattattg
    58201 tgcacaatct aactcttagt ggggcgtggt tcatttattt tttacttact ttactattaa
    58261 tcatatccca ttgagcatag gatttttcta tgttcgatcc tcttgaacta atttctcctg
    58321 taaaagttac tttatcgccc tttgtaaagg tatcagcatt gtttaagtcc ttcgcaaaaa
    58381 ttacatatga aactttaggt gttgcagaaa tatcattcca acttttatca tcgtactctt
    58441 tgtctgctat aatggctatt ctagtagtca ttgattcgat aacagttcct tcaaaagtat
    58501 atgttttacc actaatatat ttagtaaaag ctgtattttg ctcagtagct ggagtaatag
    58561 aataataact atctaagaaa gcaccccagt catgattatt tgtctctaaa aattcttcaa
    58621 attgagttag gcttttattg ctgctgttag atgtagtagt ttgagtatca gatgatgagc
    58681 tttcctgttt gttattgtca tttgcctcgt ttgatgagga aagcgagaaa cctacggtag
    58741 taaaaataat cccgataata aggagaatca taggtgtttt cttatttgtt tttttgataa
    58801 atcttacaat taacatgatt aaacctataa taaataaaac aataccagta aaaccaaata
    58861 taccgtccat taatagatcc tctttctctt ttgatattga atattataaa ccaagcaatt
    58921 cttttttctt aaaatcgaat tcttcttgat taataatccc ttcatctaac aactctttat
    58981 actttttaat ttcatctgca cttgaaattt gtgtttcttt ggaattatta tctaatatag
    59041 attgttgctt ctctatatat ttttttaaat tttccatttc attccaatat ttttttgtaa
    59101 acataacggt gttttcatct ttcgtggccg ctaatatacc tccgcgactt tcgtttccgc
    59161 ctagcaaggt aaattgtata taaccattac tcatacctgg tttttttaat tgtacggctg
    59221 atatattttt aaaggggata gttttttctc ctttaatacc ttgattaact aaatttataa
    59281 atccttttct aataattgaa atagaatcat cagttacttt aatcaaggtt tttcctggag
    59341 attttattaa aatctctttt tccatttttt cttcctcatt tctgtgatat gatttttttt
    59401 gtagaagctc atatatgagg aaagagcccg tgttgcagca cgggcttttt taatgttttg
    59461 ctgaaatcgg tttttttaat aattcttgat gtattcatac atattgcctt gcgtaagaat
    59521 attttttctt aaaatagcat tggcagacag cataacaagt gtatctgagc ttattctgaa
    59581 tagaataata ctccataaat ttttcgagat taaactgaga ttcatcagtc agttcgttct
    59641 caatatagat atttaataaa attagaatag ctattttatc tgcttctgtt tcaaattttg
    59701 agtgaaaagt tgtagaagta tcgtacaaaa ctgaaaattc aaaatgagag gcgctgaaat
    59761 gtgcaagttc atgagataaa tgaaaggctt ctgcagtttc accgtataga ttttcattca
    59821 aaaaaatgat tctgggtttt ggatagtaga aaccaggctc tttcatctcc atataaacta
    59881 ctttcaaatt gtattcgctc aacatttctt tcaatttcaa atacatacaa accatcactc
    59941 caactattca ttttcctcta aagctttagc aattgcaatc gctttacgca ttgtctcctt
    60001 agatatttct tttccatcaa aagaaaaaac agtatcgtct tctgataaat ccacatgttt
    60061 aggggtttct ctttcttctc tacctagaag gtagtctaca gagacatcga aatagtcagc
    60121 aatccgactt aattcatctg aattaggagt attatttttc cactttgcta gataaccgtt
    60181 agaatatcca aaattaattt ctaactgccg tatagatatc tttttcctct tcgccaagtc
    60241 ttttattatt tcataggtat tcatcgataa aacaaccttt ctaaatgttt acaaaaaaag
    60301 tttagaaaaa tacgcagaaa taatttgact aattctgagt aatgagctat actatatctt
    60361 gtaaacagat ttaacaacta aaaagacaac aaaaaacact attgatatgt aaatgcagac
    60421 cgccaagaaa gctttaaaat caatgttttt atgtcttatt taattatgct cttagtatag
    60481 agtattactc agatactgtc aattgaattt agaaaaaagt tgttaaattt gtttacgaat
    60541 ataaaagaaa ggaatgagaa atatgaacac accgcaaatt tttaatttcg aacaaaacga
    60601 agttcggaca attttagtaa atgatgaacc atattttgta ggcaaagacg ttgcgagtgt
    60661 tttgggttat tcaaacacta aagatgcttt gtcgcggcat gtagatttgg aagataagat
    60721 ggggtcgcga atcacgacct caggtcaatc aagagagatg acaatcatca acgaatctgg
    60781 tttgtacagt ttaatcttaa aatcaaaact tccctctgcc aaaaaattta aacgttgggt
    60841 aacaagtgaa gtgttgccag caattagaaa acatggaggt tatctaactc cagaaaaagt
    60901 agaagaagct ttgcttaatc cagatacaat cattcaatta gcaactcaac taaaagaaga
    60961 aagaactgga agattaatcg cagaacaaaa gattgcagag tacgaaccta aaatctccta
    61021 tttagatagc atattatctt ctacagattc agtaacaatt agtcagattg cagcagatta
    61081 tgggatgtct ccacaacaga tgaataaatt acttcataaa ctaggtattc agaaaaaagt
    61141 cggtaaccaa tggttattgt gcaaaaaaca catgaaccaa ggatacacaa aatctcatac
    61201 aactgagatc ccgaaagccg atggtggcac taaaattgta atgaatacca aatggacaca
    61261 gaaagggcgt ctatttatct acgaattact aaaaaaagaa ggatattacc ctcaaatgga
    61321 tttagaggaa attggttaga aaggagtttt agtatgactg acattgcaga aatcactcaa
    61381 cgagatagag aaaaaatcaa agaatatgtc gaaagttcaa agttcttaac ttacaccatg
    61441 cttgctgaaa gatttggaat tagcaaaagc tacttatctt taattttaaa cggtaaaaag
    61501 acttctgcag aagcaaacag aattatagat tcgattatca ctatgtacga attgtaaagg
    61561 gaggaacagc taatgcaata tctagaagca aaaatcccaa ttccagaagg ctatgtaatt
    61621 atctcccaag tggattatga ggagttaaaa aaagctgatg atactggtag atggatgacg
    61681 ttgccagaag tgctagaacg gattaacaga aaatatgatt ggtttacttc tagagtttta
    61741 aagaacccaa gatatagaaa tattatcgat atcgagaaaa acaaaaatgg atttgtctat
    61801 tatccagttg aaggaagaga cacatatcta tttttaagaa gtaaaacact tgaattttta
    61861 gaaacaaatt tttcggaaat cttaaggagg caagcggatg ggaaaattta atagagcgct
    61921 agtgttcagc gcaccgctaa tcatctacgc tttaggactt tggggaagca ggcaagcgtt
    61981 gataggaacg attgtttaca tggtttggat ttttatgggg cttgatgaag ctgaagctga
    62041 gtacagagcg aaaaagccaa ccgagggggc tgactaaaaa tgaatagaaa agagaaacta
    62101 gaatgtatat tactattact cagtttaatt ctttcactaa tttctctatt gggaagtttg
    62161 tatttttgat atcaacaatt ttgtggattt gggttctatt tagagtaaat atcatttttg
    62221 tttggtgatt aaggagttta ttaaaattaa ttttccctac ttcaaatgca aggtaacaag
    62281 atatagcact tttaggagga atatttagcg gtacagcttc agagtatatt ctattatcat
    62341 cgactgatcc tcctttagca attaatttct taaatggagt agctgaccat ctgcggttta
    62401 agttagcgga tgaaagttct aaattaacta acatagctgg ttctgttgaa tagttagaaa
    62461 tgattacttt tgtataaatc atatctgcag cgaagtaaga agcattaagt tcaacttcta
    62521 gttgagggcg cattcctttt atttttatcc ctgttaaaaa cgtactcaat ataaaactta
    62581 ttattgacat ccattgaaaa attgttaagt gaaaaaaatt caaaataaac accaccagtt
    62641 tttaactaaa ttataccaaa aaggagagaa gaaataatgc aagaattagt aattttgaaa
    62701 aataaagaag ctgtgactac gagcttacaa gtggcagaaa gcttcgagaa aaaacatcaa
    62761 catgttttaa gagatattga tgcactaaaa aaagatgtgt ccaattttgg acagatgttt
    62821 gtagaaggta atgaaccaga ttcatatggc agaaatcgac gagttttctt cattagtaga
    62881 gatggatttt tcttgctggc tatggggttt acaggaaaga aagctatcta cttcaaacaa
    62941 aaatacattg aagcattcaa cgaaatggaa gatgttattc gcaagaatac tgttcctcaa
    63001 acaattgaag atatgatgat ctatcaatta gaagaaatga aagatgttaa aaaagatgtt
    63061 tccatgctta aagatactat gcgaattagc ggacaacaag agtttgaaat taagcaaaaa
    63121 ggaaatatga aagttatggg agttctaggg ggaaaagaaa gccgagctta tgaagaaatc
    63181 agcaaaaaag tattctcaaa attttggtct gaatttaaac gtaccttttc aatcccaaga
    63241 tatggcgagt tacctcgtaa gagattcgat gatgctgttt catttattga aatgtggttg
    63301 ccagaaactg cgatccgtat ggaaattgat caactgaaca gacaacagag actttttggt
    63361 gatgacaatg aatagagctg aagcgctaag aatagggacg gcaattgcta attgctggtg
    63421 gaaatactat aaaccaatca tcctaagcca acaacatatt gacaagcaaa aagcatggca
    63481 acaaataaaa aagtgactcc gccggcaagc aaagagtcac aaagaaaaca catcataagg
    63541 agattttagc atatggaaaa agaactttcc actctagatc aatatttgat tgatcctgat
    63601 tggggcaagc cgaaaattga ggaaacaagt ggtcgaaaaa tcagacgaaa tcttttgacg
    63661 aatgaagaac tagcttggga tcaagatgat ttaggcaacc atgtaactat ttgggatcat
    63721 gtttatctta tccatctatc gaagcattcg aataaacctg aatatattta cgtcatcgaa
    63781 gatggcttga ttgatgcgct agaagagtac gacagagata acttgattga tatctcttat
    63841 tacggaccag gtaagaaata cattgctgaa atggaggcag aatttgatga gtgaaatcaa
    63901 agggacaacg aactttgaaa aactttttag tcgtaagtta aataaaattc tcaagaaaaa
    63961 aggaaatttt gattatttat cttgggctca cgcgtgggag attatgaaaa agaatgatcc
    64021 acaggcaacg gtaactatta atgagtacaa acactacagg gttgtttctg gaactcatca
    64081 agactttctt gttgaggaat ataaaccttt tcttatggat gaaactggga cttatgtatc
    64141 tgtctcagta acggttaaag gacacacgga aaccgaatta tttcctgttt tagattatcg
    64201 aaaccaacca gttgttaaac caaatgcaat gcaaatcaat aactcattga agcgatgctt
    64261 tgtgaaagca ttggctctac acggactggg attatatgta tttcaagggg aagatattcc
    64321 aacaccacct agaatcgata caaagaaatt aaacatgcta gagacgattc tagaagcttt
    64381 caatgagcag atgggtaaag atatgaccaa aaccttaatc gaatatgtta atgagcagac
    64441 agataaatta gggctcttag ctgataacgt tgaaactatt gaacagttaa gctatgagca
    64501 atgtgccttg atggagcgag caatagcagc taagagaaaa gaattagata agaagtgata
    64561 tgagtgttta aaccattaat cgattcatat tcagcggttc tgaaaaagtt caaaggaaaa
    64621 gacataagcg caaccatcaa tgaggaagtg aacattgatc gactaaagac gatgtatgac
    64681 ggctacgatg gtgatcgagt cattgaaatt cgttttattg atcctagacg tttcaccgta
    64741 cagcaacgaa acttcatcta tgcgctgata ggcgatattt t
//
LOCUS       DADQDV010000007        61980 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.007, whole genome shotgun sequence.
ACCESSION   DADQDV010000007 DADQDV010000000
VERSION     DADQDV010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 61980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61980
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.007"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            315..1151
                     /locus_tag="J8S10_000474"
     CDS             315..1151
                     /locus_tag="J8S10_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HAZ9629086.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQVIVLVVLLVNCYNAFVILQTLGESRLTQVKITETYC
                     SK"
     gene            1215..1646
                     /locus_tag="J8S10_000475"
     CDS             1215..1646
                     /locus_tag="J8S10_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAZ9629087.1"
                     /translation="MLREMRLGDAEALREINAEQLGYDVPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKHAEKRGIGKALMTGVEEA
                     KRRGISAIRLNSAEYRVEAHRFYERIGYHSDKMQKRFLKIL"
     gene            complement(1708..3030)
                     /locus_tag="J8S10_000476"
     CDS             complement(1708..3030)
                     /locus_tag="J8S10_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HAZ9629088.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRNVKPSIPQLGVGLMVSL
                     TFFILGQICNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(3184..4824)
                     /locus_tag="J8S10_000477"
     CDS             complement(3184..4824)
                     /locus_tag="J8S10_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HAZ9629089.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAAFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAATILEKYEDKITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQTILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     KGLTPGQIPFARKRSEFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQKLNREEITDIKEAVESAKWVPEYKSLED"
     gene            5157..5627
                     /locus_tag="J8S10_000478"
     CDS             5157..5627
                     /locus_tag="J8S10_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HAZ9629090.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLGANKAIISELTV
                     GGLVDSLALAEGFIGEDIYEMFSEIRQLKKGENCIEVHHESPNVRFKRGDNEMIFNNH
                     VSDHTELYGIVNQILTELFGLGPYAFKEENGNPKLNEEWQETIEIQRNNPHLFQ"
     gene            5849..6952
                     /locus_tag="J8S10_000479"
     CDS             5849..6952
                     /locus_tag="J8S10_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HAZ9629091.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHQLIIPHVLKDVELPDTTTHFDKETLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDDGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            7236..7916
                     /locus_tag="J8S10_000480"
     CDS             7236..7916
                     /locus_tag="J8S10_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HAZ9629092.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGPLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            8006..9040
                     /locus_tag="J8S10_000481"
     CDS             8006..9040
                     /locus_tag="J8S10_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HAZ9629093.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTVPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNAFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            9054..9389
                     /locus_tag="J8S10_000482"
     CDS             9054..9389
                     /locus_tag="J8S10_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629094.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPIPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEQKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            9373..11853
                     /locus_tag="J8S10_000483"
     CDS             9373..11853
                     /locus_tag="J8S10_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629095.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLTDIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISPSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSLQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYESKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWKLTAGPTS"
     gene            11909..13468
                     /locus_tag="J8S10_000484"
     CDS             11909..13468
                     /locus_tag="J8S10_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAZ9629096.1"
                     /translation="MRRKLLLLKSEMLEGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     VSVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQIRYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFAITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            13465..14829
                     /locus_tag="J8S10_000485"
     CDS             13465..14829
                     /locus_tag="J8S10_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAZ9629097.1"
                     /translation="MKIVIIGASHAGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQTIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEYTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            15000..16070
                     /locus_tag="J8S10_000486"
     CDS             15000..16070
                     /locus_tag="J8S10_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9629098.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAIGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            16085..16753
                     /locus_tag="J8S10_000487"
     CDS             16085..16753
                     /locus_tag="J8S10_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9629099.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEANELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            16773..17351
                     /locus_tag="J8S10_000488"
     CDS             16773..17351
                     /locus_tag="J8S10_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAZ9629100.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            17752..18663
                     /locus_tag="J8S10_000489"
     CDS             17752..18663
                     /locus_tag="J8S10_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAZ9629101.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(18751..19668)
                     /locus_tag="J8S10_000490"
     CDS             complement(18751..19668)
                     /locus_tag="J8S10_000490"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HAZ9629102.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELHKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            19870..20307
                     /gene="zapA"
                     /locus_tag="J8S10_000491"
     CDS             19870..20307
                     /gene="zapA"
                     /locus_tag="J8S10_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HAZ9629103.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            20366..20914
                     /locus_tag="J8S10_000492"
     CDS             20366..20914
                     /locus_tag="J8S10_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HAZ9629104.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            21029..23389
                     /locus_tag="J8S10_000493"
     CDS             21029..23389
                     /locus_tag="J8S10_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HAZ9629105.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEEQTIT
                     NWLQETEDGLKVQRLRGGIPIPKLENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLYDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNAYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            23476..23790
                     /gene="trxA"
                     /locus_tag="J8S10_000494"
     CDS             23476..23790
                     /gene="trxA"
                     /locus_tag="J8S10_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HAZ9629106.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            23972..25750
                     /gene="uvrC"
                     /locus_tag="J8S10_000495"
     CDS             23972..25750
                     /gene="uvrC"
                     /locus_tag="J8S10_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HAZ9629107.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKNFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELASKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMAKNDKHKTNELLFGTDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            25895..26794
                     /locus_tag="J8S10_000496"
     CDS             25895..26794
                     /locus_tag="J8S10_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9629108.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            26787..28049
                     /locus_tag="J8S10_000497"
     CDS             26787..28049
                     /locus_tag="J8S10_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9629109.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPVRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            28210..30108
                     /locus_tag="J8S10_000498"
     CDS             28210..30108
                     /locus_tag="J8S10_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HAZ9629110.1"
                     /translation="MDRYLDLLSEKFPSTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETDISQFTIFTAYPEYALTTDWYKEQDKS
                     QLIHHLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFAP
                     KNSKNLSEREQEELEKIHQALSILQFKSEHQLLDRRPEFKMDDRKLLEKIDYEASTID
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTAKEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDTKEEGSAIINGHTPVKVKKGESPIKANGKVFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRDTTKGMELQQQITQLKR
                     LLDYRKDD"
     gene            complement(30438..31157)
                     /locus_tag="J8S10_000499"
     CDS             complement(30438..31157)
                     /locus_tag="J8S10_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HAZ9629111.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIGQIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFTTHEVKIVSD
                     SLLSNLLPDPYFVNSYHHQAVKDLSPLLKAIAFSNDGLIEAVQSKDDMHKILGVQWHP
                     ELTHRVHPSEQRLFDFFVNEF"
     gene            31494..31826
                     /locus_tag="J8S10_000500"
     CDS             31494..31826
                     /locus_tag="J8S10_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629112.1"
                     /translation="MKQVLEALEQIRKAEEENEKRAQTLRQQLKIYATEKEQELETIQ
                     TNYRQQLKQLVEEKEQFEIQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            31813..33816
                     /locus_tag="J8S10_000501"
     CDS             31813..33816
                     /locus_tag="J8S10_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HAZ9629113.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFINKLKEVLDLKEKWEQLTEERDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAVIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKIKERFIHATYLIVLQGWVDAEEKQNLLHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLVEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLLVLPRGMKRFVKFFEILSIPSIIWGLIYSSFFGQSLPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALVGAMLIKNTAFVYLGAGLSIIAALCILIVPIIQTPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            33835..34305
                     /locus_tag="J8S10_000502"
     CDS             33835..34305
                     /locus_tag="J8S10_000502"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HAZ9629114.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            34326..34910
                     /locus_tag="J8S10_000503"
     CDS             34326..34910
                     /locus_tag="J8S10_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HAZ9629115.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQVETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAVTEMENWDESEQ
                     IQFIKNALYSLPLTGKVAFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            34925..35911
                     /locus_tag="J8S10_000504"
     CDS             34925..35911
                     /locus_tag="J8S10_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HAZ9629116.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNIDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFESETIRKRVRQVYDA"
     gene            35901..36212
                     /locus_tag="J8S10_000505"
     CDS             35901..36212
                     /locus_tag="J8S10_000505"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HAZ9629117.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            36234..38015
                     /locus_tag="J8S10_000506"
     CDS             36234..38015
                     /locus_tag="J8S10_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HAZ9629118.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            38008..39384
                     /locus_tag="J8S10_000507"
     CDS             38008..39384
                     /locus_tag="J8S10_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HAZ9629119.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            39391..40026
                     /locus_tag="J8S10_000508"
     CDS             39391..40026
                     /locus_tag="J8S10_000508"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HAZ9629120.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            40056..41411
                     /locus_tag="J8S10_000509"
     CDS             40056..41411
                     /locus_tag="J8S10_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HAZ9629121.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(41603..42997)
                     /locus_tag="J8S10_000510"
     CDS             complement(41603..42997)
                     /locus_tag="J8S10_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HAZ9629122.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRTQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            43089..44060
                     /locus_tag="J8S10_000511"
     CDS             43089..44060
                     /locus_tag="J8S10_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HAZ9629123.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            44057..44839
                     /locus_tag="J8S10_000512"
     CDS             44057..44839
                     /locus_tag="J8S10_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HAZ9629124.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(45008..45379)
                     /locus_tag="J8S10_000513"
     CDS             complement(45008..45379)
                     /locus_tag="J8S10_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HAZ9629125.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            45513..45956
                     /locus_tag="J8S10_000514"
     CDS             45513..45956
                     /locus_tag="J8S10_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HAZ9629126.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(45999..46808)
                     /gene="yidA"
                     /locus_tag="J8S10_000515"
     CDS             complement(45999..46808)
                     /gene="yidA"
                     /locus_tag="J8S10_000515"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HAZ9629127.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(46827..48194)
                     /locus_tag="J8S10_000516"
     CDS             complement(46827..48194)
                     /locus_tag="J8S10_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAZ9629128.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(48178..49008)
                     /locus_tag="J8S10_000517"
     CDS             complement(48178..49008)
                     /locus_tag="J8S10_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HAZ9629129.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLKDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            49171..49608
                     /locus_tag="J8S10_000518"
     CDS             49171..49608
                     /locus_tag="J8S10_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HAZ9629130.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            49684..50304
                     /locus_tag="J8S10_000519"
     CDS             49684..50304
                     /locus_tag="J8S10_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HAZ9629131.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            50493..50999
                     /locus_tag="J8S10_000520"
     CDS             50493..50999
                     /locus_tag="J8S10_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HAZ9629132.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            51016..51915
                     /locus_tag="J8S10_000521"
     CDS             51016..51915
                     /locus_tag="J8S10_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 and DUF4163 domain-containing protein"
                     /protein_id="HAZ9629133.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            52002..52886
                     /locus_tag="J8S10_000522"
     CDS             52002..52886
                     /locus_tag="J8S10_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HAZ9629134.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(53078..53149)
                     /locus_tag="J8S10_000523"
     tRNA            complement(53078..53149)
                     /locus_tag="J8S10_000523"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(53114..53116),aa:Arg,seq:ccg)
     gene            53209..54543
                     /gene="rpoN"
                     /locus_tag="J8S10_000524"
     CDS             53209..54543
                     /gene="rpoN"
                     /locus_tag="J8S10_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HAZ9629135.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            54746..55783
                     /locus_tag="J8S10_000525"
     CDS             54746..55783
                     /locus_tag="J8S10_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SorC family transcriptional regulator"
                     /protein_id="HAZ9629136.1"
                     /translation="MLDEIKMIESVAPDIIEVLQERYKILRNIYWMQPIGRRSLSESM
                     GITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSLENFMDQLLGTHQTEQQLA
                     EYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEGENIIAVMGGTTMAVVAEQ
                     LSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKANGNHRALYVPEQLSLATYN
                     SLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEKELVMLKQANAVAESFGYF
                     FNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAIRAYMKNAPKQTWLITDEA
                     AANEILKGVTL"
     gene            55824..56825
                     /gene="gap"
                     /locus_tag="J8S10_000526"
     CDS             55824..56825
                     /gene="gap"
                     /locus_tag="J8S10_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HAZ9629137.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            56935..58125
                     /locus_tag="J8S10_000527"
     CDS             56935..58125
                     /locus_tag="J8S10_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HAZ9629138.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            58229..58984
                     /locus_tag="J8S10_000528"
     CDS             58229..58984
                     /locus_tag="J8S10_000528"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HAZ9629139.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            59100..60398
                     /gene="eno"
                     /locus_tag="J8S10_000529"
     CDS             59100..60398
                     /gene="eno"
                     /locus_tag="J8S10_000529"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HAZ9629140.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
     gene            60797..61936
                     /locus_tag="J8S10_000530"
     CDS             60797..61936
                     /locus_tag="J8S10_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HAZ9629141.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
BASE COUNT        20472 a        10844 c        13067 g        17597 t
ORIGIN      
        1 gaagctgttt tttgaaattg ttccttgtga ctcggagctg aacggcaggc tcacgacctc
       61 tttcttaaac ggtgttcaaa agcttgcatc tgcggtaata agttcaacca aacgaaaatt
      121 atgaggagct atttttgttt ggctgttctt attacttgat gcaggacagc tttttcacaa
      181 cctcttttcg tttagcacta aatttcctta aaaagtagaa aagctttcga agcctcgttt
      241 gtttctttta ctgtataata aaagaaaaga gtaacaatcg ctaaaagata taaacaagag
      301 aaaggaaata caagatgatt ggtctgattt attttgtggt gatcgttctg gcgaacacag
      361 ttggcgctat ttccgggatg ggtggaggcg tgttgatcaa accgattctt gatcttatcg
      421 gcgcccattc tgttgcaggg atttcttttt actcaacagt tgcggtattc acgatgtcca
      481 ttgtttcgac tgtgcgacaa gtatcaagcg ggaaatcact gaattggcag attgtcggtt
      541 gggtatctag tggagctgtt gttggaggag tagtcggcaa cattgtattc gaagtttttt
      601 tacagttatt tgaaaacgag aagcatgtgc agctgatcca aatttttttg acggtattga
      661 ccttggtttt tgcgttcttc tacaccaagc atcatcagcc aaaatttcat ttgacgtcat
      721 ggacttggta ccttatatgt gggggggttc tgggcttttt agctagtttt ttaggtattg
      781 gtggtggacc agtcaatgtt tctttgttga tgctgatgtt tgcattgcca ataaaagaag
      841 caacactata ttctctatct acgattttct tttctcaact ggcaaaattg gtaacgattg
      901 ctttaacaag tagctttatg cgctttgatt tatctatgtt gttttatgtt atccccgctg
      961 ctgttattgg aggtttgtgg ggagcaagat ttagcagggt tttgtctcca aaaaaagtga
     1021 cctttatttt tcaagtaatt gtcctcgtgg ttcttttggt caattgttac aatgcctttg
     1081 tcatcttaca aacattagga gaatctagac taacgcaagt caaaatcact gaaacatatt
     1141 gttctaaatg aaaaaaggag tatactgtga taaaaaaatt catttaaaaa aataaaaatt
     1201 ggctggtgat ttggatgttg cgggaaatgc gtttaggaga tgcagaagca ctacgagaaa
     1261 tcaatgcgga acaattagga tatgatgtac cattaaccgt tacggtgaga caaatgaaga
     1321 aactgttgaa ggagccagaa aaaaattttt tcttggtcta tgaagatcct acttctaaaa
     1381 aagcagctgg ctatgtacaa gcggagtcct atgaatcgat tttcagcgat ccgatgttca
     1441 atattatggc acttgctgtg tctaaacatg ctgaaaaaag aggaatcgga aaggccttga
     1501 tgactggcgt agaagaagcg aaaagacgag gaatatcagc aataagactt aattctgcag
     1561 aatacagagt agaagcacac cgattttatg aacgcatcgg ttatcattcc gataaaatgc
     1621 aaaaaagatt tttgaaaatc ctgtaaattt ttatcaaaaa atacctggtc atcaagccga
     1681 tacttgatga tcaggtattt tttttgacta agaaagtaat tgcatcaaga aacctgagat
     1741 gatcaaaacg atggcaccac caagccgatt gcccatttga gcaaaagcaa taagttccat
     1801 ccgattagct gcagataaga cagctacatt tcctgtacca cccatcgagt tgttgcataa
     1861 gccagcagta atagttgatt cgattggata taaaccaaac aaacgaccga caaatcctga
     1921 aactactgaa atcgcgataa cacttgtcaa acataagaca acaaattgcc atgtcaaagc
     1981 agaagccaat acatttagat tcaataacgc aataccgata ccggcaagaa cagctgctgt
     2041 caagtttttg acaatcaagt tgttgaacat gatagctgca tcttcgtaat attctggtaa
     2101 taggtttgcg attttacaga taacaacgat aatgatcatg aatgcgtaag catggacttt
     2161 aggaacaaaa tagttacaga tttgtcctaa gatgaagaaa gtcaatgata ccatcaaacc
     2221 gacacctaat tgtggaatgg aaggttttac atttctaggt tttccatcgc caaggtcgcc
     2281 tttttccatt aatttaccat taccgttgaa ttttggcatt gattgtcccg cacgagcaac
     2341 taacgctgca ccaatgatag ctaggacatt tgtcattgct gtcgcaggaa tcaggcggga
     2401 aatgatagaa gaagcgtccg tacctaaaac atttgcataa atcgttgata aaggtacagc
     2461 tccggctcca acaccaccag ccattgcggg caatgagata tataaaacgg aatttgcaaa
     2521 accatttccg ataagcatac ctacgagtcc tacggcaaaa aaggagacga ccattgaaat
     2581 aagtgcaacg ggaataaaac gaacagaagc tttcatcaat agattacggt tcataccaag
     2641 gatgctacca gtaatcaagg cagcaatata aaagtctaaa aagcccatat tgctgacaaa
     2701 gttttctgtg gattttacta catactcagg taagatccca aatgtagcaa tcgcggcaga
     2761 ggcaaagatc gcaaaaacgg agccaccacc taaataactt ttgacgatag ggatttttgt
     2821 tccgataaaa tgaaataaat taccgaaaat gaccaaaaca gcgattgggc caatcatatt
     2881 cgtcggtaat tttcctaaag ccattgcaat gatcaggaca aggaccatga tcaaataaag
     2941 gggcaaactt acgccggtaa tttttgttga ccaaaaccct tcttttttct tttcctcaac
     3001 tgcagttgcg gttgttgttt tttgtgccat ttttacagat cctttcttat tctgtatcgt
     3061 atgaaaaaag ccaaagagaa gcggcaaaag agcagtagtt ggctggctgc tgttttgccg
     3121 cagtcgcttt tttcttttta gacgtcatac aaagtttctg tatgttcttt tactataaca
     3181 atcttaatct tctaaagatt tatattcagg aacccattta gcagattcaa cagcttcttt
     3241 gatatccgtg atttcttcac gattcaattt ttgtgcaaca actgattttg cgacagtttc
     3301 agcaatcgtt tgagagaatt cagtgatttt tgctactgga ggcaagatag ctgctcctgg
     3361 ttttgttaca tcaacgattc cgcctaatgc tcgactagct tgagaaatga tttcagcatt
     3421 tactcgtgta gctgttgaag caatcaaacc aagccctaaa cctgggtaca tcaacgcatt
     3481 atttgcttga ccgatttggt aagttacacc gttatattcc acatcagcag cagggatacc
     3541 tgttccaact aaagcttttc cgtccgtcca ttcaatcaaa tcttttgctt ttgcttctgc
     3601 caattttgtt ggattagaca aaggcatgat gattggacgt ggggtatgag ccgccatttc
     3661 tttcacgatt tcttcagtga atgctccagg ttgggtagaa gtaccgatca tgatcgttgg
     3721 atggattgct tttacaactg cttctaagtt tgtcaattca tcagcattag tgaattctga
     3781 gcgtttacga gcgaatggga tttgaccagg agtcaatcct tttgtatctt caaacaataa
     3841 accctgttta tctacttgat agaaatgttg gcgtgcttct tcttcaggta caccttgacg
     3901 gatcatttca tctaaaagga tgtttgcgat acctacacca gcagtaccag caccaaatgt
     3961 caagatcgtt tgatctttca attgctcacc tgatatattc aatccaccta atacaccagc
     4021 tagtacaacg attcctgtgc cttggatatc atcattgaaa gtagtgattt tatcttcgta
     4081 tttttctaag atcgttgcag catttcctcg tccaaaatct tcccaatgta ataacaattc
     4141 tgggaataat tcagtagctg attgaacgaa ttgatcaatg aattcgtagt aagtttcgcc
     4201 ttctacacga gcatgacgat tccctaagta taatggatta ttcaataatt cttcgttatt
     4261 agtaccagcg tcgattgata caggcaagac ttgtgcagga ttgataccag ccgcagcagt
     4321 gtagaccatc aatttaccga tagcgatgtc aacaccgttc acaccccagt cacccatacc
     4381 taagattcct tctgcatctg tcacaacgat caaacgaatg tcgcgtccat ctgctgcgtt
     4441 tttcaaactt gctttgatat tttctggttc gtcgattgaa agaaatgcag catcttgtgg
     4501 tttcaagaaa atttcgttgt attgttcgat tgaatccgca acgacaggat cataaacgac
     4561 aggcatgaat tcaactaaat gttcgcccat caatttataa aacaatgtcc ggttcgtatt
     4621 gaatagattc attaagaaga tacgtttttc caaatcggtc tgtttgctta agtattgacc
     4681 gtaagcttgg acagattgtt gttccaatgt ttggacagta cttggaagca taccagtgat
     4741 tccgtatttt gcccgttctt cttttgtaaa agctgttcct ttatttagaa aaggattatt
     4801 taataagttt agccctgtaa gcatgaatga ttcctcctaa gttttaatac aaacgaagta
     4861 taggagtcag atgaggatat agtcaaaaag agcaggtata ataaatttta tttatatgag
     4921 taatagagtc aaaagaaatc aaaatagcgg tatttgttct ttttatatca acaatccttg
     4981 cttgattact atgcgtatct cttatatgct aaagaaagaa aagtagaaga ataaaggata
     5041 tgttagatag ataaatagaa tctctgaaga ataaatcacg tgatcgtgac gataaaatac
     5101 acttacgtca ggtgataaaa aatacataag tagaaaacta agaggaggaa cagaaaatga
     5161 aagaagttca attgatcaga aaaagcgaac tatcagaagg tggttgcaat gcatgcggcg
     5221 tagtagaagc aacaagctat acattaaagc ttggtgccaa caaagcgata atctctgagt
     5281 tgacagtagg cggtcttgtg gacagtctgg cgcttgctga aggttttatt ggagaagata
     5341 tttatgagat gttttcagaa atccgtcagt taaaaaaagg ggaaaactgc atagaggttc
     5401 atcatgagag cccgaatgtg agattcaaac gtggtgataa tgagatgatc ttcaataatc
     5461 atgtgtccga tcacaccgag ctatatggaa tcgtgaatca aatactaact gagctttttg
     5521 gattgggacc ttatgcgttc aaggaagaaa acggtaatcc aaaattaaac gaagaatggc
     5581 aagaaacgat tgaaatacaa agaaacaacc cgcacttatt tcaataggca tccacagtat
     5641 ttcgtaaaag ggactttgac acgacttttg tcaaagtccc atcgtttttt atctatttgt
     5701 gttctaaaca tttctttcag agtagtaaca actggaatga ctgaaatgta aacagattat
     5761 ttgcctgtat caatacggaa gagtaatata aagtgtgtaa acgctatcat attattcatt
     5821 caatttttta tagagggaag gcattgaaat ggaaaaaacg tatcaagcag gtacaaatga
     5881 aggaatagtg gattttatca atatggaaga tttagaaata gccgcttcac aagtgattcc
     5941 agctggtggt tatggttaca tcagcagtgg tgctggcgac ttatttactt atcaagaaaa
     6001 tgaacgggca ttcaatcatc agctgattat tcctcatgta ttaaaagatg tagaattacc
     6061 cgatacaact acacattttg acaaagaaac gctgactgca ccaatcatca tggcaccagt
     6121 tgctgctcat ggcttagctc atgtgaaggc ggagaaagct tctgcaaaag gtgtagcaga
     6181 ttttgggacg atctatacag caagttctta cgcttcttgt acattagaag agataagaga
     6241 agcaggcggg gagaaagcac cgcaatggtt tcaattttat atgagcaaag atgatgggat
     6301 caatttggat attcttgaag tggccaagcg taatggagca aaagcaatcg tattgacagc
     6361 ggatgcaaca gttggcggaa accgtgaaac agaccgcaga aatgggttta ccttcccact
     6421 gccaatgccg atcgttcagg cttatcaatc aggagtaggc caaacgatgg atgctgtgta
     6481 caaatcttcc aaacagaagc ttagtccaaa agatgtagaa tttattgctg ctcattctga
     6541 tttgccagtc tatgtgaaag gtgtccagtc agaagaagat gtctatcgtt cattagaatc
     6601 tggtgctggc ggaatctggg tatctaatca tggtggccgt caactagatg gtggtccagc
     6661 agcgtttgat tcgttgcaat atgtggcaga agcagtagat aaacgtgtac caatcgtgtt
     6721 tgacagcggt gtacgacgcg gacagcatgt tttcaaagca atcgcatcag gtgcagatct
     6781 tgttgctatt ggcagacccg ttatttatgg attgtcttta ggaggaagta caggagtcca
     6841 tcaagtgttt gatttcttta aaacagaatt ggaaatggtc atgcaattag ctggaacaca
     6901 aacagtagaa gatatcaaaa aaataaaatt gcgtgagaat cgttttattt aagaaacaaa
     6961 tgacgaaaaa aataggagtg cggcagatga tgccgtactc ctatttttat agttcaagga
     7021 tgtcactaat agaataattt gaaacgaaaa aataaaattg aaatattttt tcatacttaa
     7081 taaaaaagga agaatattca tgtaaacgat tttattgttt ttttctcttt tatacaaaaa
     7141 gggtcataat ttcaagtaag cggatgaatt catgaggatt ttttgcatac tgtctctact
     7201 atacttaggt cactaagaaa aaggagtgat ttattatgaa aaagaacatg attgggacat
     7261 tattactttc aacacttctt ctaggcggct tggcaacacc agcttttgct gagggtcaag
     7321 cgacttcaaa aggagatatt acctttactg aaccaacaaa taccgtggag cctcttaacc
     7381 ctactgatcc ttcaaaacca gtagagccag cagatccgga aaatccagca actggccaga
     7441 caggtccttt aacactggat gtagttcccg aattgccatt tggtacacac gagattgaaa
     7501 gcggaacaaa aacgtatcaa gtagacgctt caaaaaacga tacaccttat ctccaagtat
     7561 cagatcgtcg aggtgtaggt gcagatggcc aagcacaagg gtggaacgtg acagtttcgg
     7621 tttcagattt tgtaaacggt tcacaagttt tgcaaggcgc tgaattagat tttggaacat
     7681 ccactgttaa aagtacgtca gataacgaat ccactggacc aactagtcaa actgtaactg
     7741 ggttgagtaa agcaagtgca gcgacaccaa tatttacagc agcaaaagat caaggtctgg
     7801 gaacatggct ttctgtttat gatccagcaa atatcacact gaaagtgccg aaagcagcag
     7861 ctggaacatt cacggctgat ttgacttgga acctcgtggc tggcccagta gcatagagta
     7921 tgaaataaat tcaacaaact gcggtgaaaa tactataggt gaaggatttt ttaccgcagt
     7981 ttttgttgaa aggatgtggt ggacaatgaa tcaaagtaaa cgactgtttg tttcgttttt
     8041 ttctatttta agtctatttt tcatttttcc gtcaatcagc caagcaaagg attcagcagg
     8101 agactttgga atcaaaccgg tatttccaga gaaccaaata gataaagcaa tcggttattt
     8161 tgatttatta gtggcaccgg aacaaaatca gacactagaa gtaattatca gcaattcttc
     8221 agatgaagaa cgaacatttg aggtctctgt caatccggcg gtaacgagtg atggtggaac
     8281 gatcgattat agtcaaaaaa acccaacgtt agatgagaca ttgccgtttg atgtccgtga
     8341 cgttttgctc attgcgaaaa aggaaatcaa tgtatcagca catgcagaaa caactgtacc
     8401 tatagaagtg aaaatcccag caaaaagctt taagggacgt gtattagcgg gtattcatgt
     8461 ttcacctaaa gaagaagctg aaacagaaaa tgctacagaa ggagcacaaa tcaaaaatcg
     8521 tattgcttat aatctcgcag tcgttttaca agaaagtcaa gagacgatag aaccggatct
     8581 gaaactttta tcaggagatt tggacgaggt caacgcaaag ccaactgttc agcttcgttt
     8641 ccaaaatcct cagcctagga ttatcagcaa tttgatattt acgagcaaga tcttttatga
     8701 aaatcagctt tatattgaaa atacgtctaa tgcattttta gttgcaccaa attcgaattt
     8761 tcacttgaat cttgatttag ctggtgataa agcaaaagcc ggcgattacc gcgcagaaat
     8821 catagcaaaa tcaggcgaca gtaatgaatg gcgatttaca caaaacttta cgatcaaaaa
     8881 agaaaaagca caaaaagtaa atgaaaattc cgtttttgca gtacaagaac aatctttccc
     8941 atggctttat gcaggattgg ttgctgcagt tctagtgtta tggttgattt tgctgttttt
     9001 gtgggtccac aagaaaaaga aaaaaggaga aacaacatga tgaggtgatt tcgttgaaaa
     9061 catcgatctt attgggaggg attattgcaa gtttgctgtt cttcagctgg caagagccag
     9121 tccaagcaga taccaaaagt tcaggtacga ttacatttta tgatctaagt ccaattccgc
     9181 atccaagtgg ttcagtcaat ggcgcatcaa aacagcagac acagctaccg atttataaag
     9241 aatctaatca acatggcgta ttcccggaga cgaatgaaca aaagatccgt tttctttatt
     9301 tgatcattgg tatagaatta tggcttcttg cgtggttgtt gttatggaga agaaaggaaa
     9361 aggaggatga acatgttgct acaaaataaa ttttcatttt ttcgctcctt cttttttact
     9421 tcgctttttg ttttaagtat atttatcttt tcaccttcgg cagaagctgt tggagcaacg
     9481 cctcctgcca tttcttatga tccatacacg tatgaaaata tcgtacctcc aaatggtgga
     9541 cgtagtgcag tcaatggcgg gaagcttgtc caactaactg gggctaacca attgcctaaa
     9601 ttgactgcta cttatttgaa cgatggttca aatgatcctt ggaaaggtgg cacggtccgt
     9661 tttcattggg aaagccatgt gaaactaaca aatgtacttg atttggtgaa tatcactgca
     9721 caaggatttg catttgtggc gatcatcaat ttgccggaac atgtatcaag cagtgatgta
     9781 ttaaaagcaa ttgactggaa caacgcctac ttgtatattg ccggtgcccc catcaaggtt
     9841 actagcggaa gtttattatc agcaggaagc cataccttgc gttttgggat ggggtcgtgg
     9901 gatacaaata ctctattgac agatattatt gctattatta cgcgaggcga attcaacgtg
     9961 gacgatatcc cgcttcaatt tgatgttaca gctaatgtcg cgaagatgac agaaaacgga
    10021 gataaatatg atacgagtcc aaacaaaatt ttgaccaagg gtaaattaca accttctatg
    10081 tctaaaaagg ccgttttttc tgttgatttt tatgattcga ataatattat ccaagatcgt
    10141 atgttcaatt cgattttagc tccagctgca ggtagatttt atcctaaatt aactggcgga
    10201 aacttgaatc caggagcata tgcattttct gcaagtgcag agataaatac gtggaatagt
    10261 tacatctcac caagtgattc aacaggaaaa tataatacat ttgctgatac cacagaatac
    10321 gtggatggaa ataaccagaa ccttccaggc tctaccaata gtcggacatt gacgatgggg
    10381 ctgactgaag gacgttttga tcagttgcca tttagtcgct ttgatcgcgt agtcaactat
    10441 tttacaggaa aaaacgttac acaaggagca atactgactc atactccagc aagcacaagt
    10501 ggattgaatc agacagccaa tatcgtgtac agtgggaaag atgcgcaagg cggattgctt
    10561 tctcctgttg ctttaaaggt attggagcag tacaagctag acggaacggt tttaccaaca
    10621 aacttaacag ccgatagtca gtggggaaag ctcctttctt ctgcatcgta ccaagtcacg
    10681 gccaattggt cagcaactga actaaaaaag ggttcgatcc attacaggct ttattcgaaa
    10741 ggaacccaaa aattagcgac aggatggaca gatcaacttt tccaaacgat ccaatcaaat
    10801 aacgggggtg taaatacagc tacttctaca ctacctgcat tggcttcagg gcaatattat
    10861 tttgattatc gcttggtgga cgatgtactt actaacatgt atccgtcttt tgcgtacaaa
    10921 tggcagtctg aacaagctgg aatcaccact cttcctcaaa taacagtggc taattttcca
    10981 tctgtgagtg cagatagtca gctaaaaaac cttagcagac aacctgagac aggagatccc
    11041 ctgtctgctc tatcaggaga tacgattcaa gaaaatgtga cattcacgtt aacaaaatct
    11101 ggggatgcga taaccgacaa aaaaatcacg atctcacttc ctgaaaatac tacttatatc
    11161 aatggttcct taaaattaaa tggtacaact atcgcagata ccggcattca acaaggagtt
    11221 tctgtcccag cagatctatt gagcaaaata ggagatacca ttcatcttac ttacaactat
    11281 caattaaata ctgtagatac ttctttacaa tccgtcagca tactgacaaa ggcagctgta
    11341 ctttccagca atattacatt agcagatggt gctaagcttc ctaacccagt tgtccaaaca
    11401 tctgctaaaa caattcttgt ccccaaacaa gaattaacat tagttaatgt accagatgat
    11461 tttacatttg gtaacgatct ccccaaaccg ttgaagacaa gttattatga atcaaaaggc
    11521 gatttttctt ttgatgtgcg ggatactcgg cttccaagca cgtctccttg gcaactgaca
    11581 ggtacattga cttctttatt taagaatgat caaggtcaag aattaagcgg aacaaaatta
    11641 tacttcaatc attctggatc aaagcaattg attcagcaag gtcaaaacac gttgatttat
    11701 gagagtgatg gaacagctaa aggagaggtt ctcgttgact ttcccgatac cgatggttta
    11761 ctcttagagg taaatagcag tacgaatgct caacctggcg caacgtatca aggcatggtc
    11821 acatggaaac tgacagctgg gccaaccagc taagtgatta gaatttgtat ggatctgtga
    11881 taactgtcac agatcctctt tttcaaggat gagaaggaaa cttctgctgt taaaatcaga
    11941 aatgcttgaa ggagtggact tggaactttt cagtttgctt gaaaaaaatg aacaacggca
    12001 aatcaaactt ttccaacttt tattagagga aaaaggagag gtttccgtta ataacgtact
    12061 tacccgctta tcagttgatc gggctacctt gaaagaagat ctgttttatt tacaagctaa
    12121 cttggaaaat atcaaacaat tggaaattgt tatccaagaa gggaatattt tattaatcag
    12181 acatggaaat atagcagcag tcgatgttta ttatcattgt tacttgcgct attctacaaa
    12241 atatcagata cttctttatc tgttggaaaa tggctcattt gatcggcaga aacttgtcat
    12301 ggaacttaat atcagttcgg ctactttgtc tcgcagagtg aaggaattaa atgattcttt
    12361 aaatgagttt catctgaaaa taaaaagcgg gcggctgacc ggtccagaaa gtcaaattcg
    12421 ttatttttat ttccaattat tttggtttgg acgtccctat cttgaaaaca aaaaagaata
    12481 cagtgattta tcaggaaaca cttttttaga tctgctgcaa aaagagttta gttttgctat
    12541 tacagaagaa ggacgattga aatttgaaat atggctttcc attatgaaga agcgaatgcg
    12601 ctgtacgaaa aaatccaaac cagattatag caatcttcct gttggattgt ttcaaacgac
    12661 acaattttta ttggacctcc atacattttt gacccgttac ttctttcaat atgcctttcc
    12721 ttggaatcaa aatgaaacgt tggtttttta tcttttcatg atcagtaact ttacattaga
    12781 tacacataac tcgcatgtcc aggagttttt gataagcgaa aaatacaaag acgacgtagt
    12841 agctcaattg aatcgaacgt ttaaacaatc gatagaagaa tatttctctt tttatgtttt
    12901 tccagaagag atttcgcaaa agattgcgtt gacagtgatg caaaatcacg ctcattttgc
    12961 ctattttaga ggatggatga atatttttgg ccaagaagga ttaaaacagc ggttaactga
    13021 agtagaagat aaacaattcc tggttttatg tgaaagattg gtcagacaaa catttgctat
    13081 tgttgatttt actgaagtag acgaggaaaa tgcccgcttt gaattatttg ctcgctatgc
    13141 atctatttta cggacgctga tcaagcagtt agaattacgt ctgcaaattg cttatgatct
    13201 tccttatgaa aggctaatgg cggatatcgt gaaagaaatc atccaggaac aattgctgaa
    13261 tacgatcaaa tatgatttag tcgaatacga gaaagaaaag cagtatgata tcattttgac
    13321 tagccaattg aaagagtacc cgtcacagaa gtccgctaaa gtttttgtat tcactagcaa
    13381 cgaatataat tatgatttcc cctatttgaa ccaattttta aaagaatgtt atttagaaaa
    13441 attgaattta aggatgaata aaacatgaaa atcgtgatca ttggtgcttc ccatgcaggc
    13501 atcacagctg ccctaaatct aagaaaactt caaccgaaag cagaagtttt actgatcgat
    13561 gaagatcata aagatggact aggctatgtt tcaaatggaa tcaaccttta tttaaaagga
    13621 aagatacgta gtttagctga agttgcccat aacatgcgga ctcttcaaga aagtggggca
    13681 aaactgatca ccgaatggag agtaactgaa cttgatccag acaaacatca gctcatcctc
    13741 gcatccaaag aaggaaaaaa cgagaccata acctatgata aattaatcgt agcgacaggt
    13801 tcctctcctg tcaccttgta taaacaaatt gaagctgaaa atgtctacac ctataaaaat
    13861 ctagtgcaat ctaagcaagt acttgccgct ttaaaagaag caaaagaagt agtgatcttc
    13921 ggtgctggtt acattggatt ggaattagca gatgctttga gaaataaagg atacattatt
    13981 catctagttg attatatgcc gaatgtttta tcaagatatt tcgataagga tatgatcaac
    14041 agttttcaaa atcagctgca aactaagcaa ataaattttt atccaaatga attcttgatc
    14101 gattggaaaa aatcagaaga gaaagtagta tccgtacaac ttctgtctca aacaataaag
    14161 gcagatatgg tcattttttc tgcccaaact cgtcctaata cgacattgtt aaaagaaaaa
    14221 gtggctttgt atgaggatga gactgtgata gtcaatgaat atctgcagac aagtgatccg
    14281 gacatctatg cgattggaga tatcgtccca gtcagttttg acaaaaataa acggcatctc
    14341 tttttacctt tagttactcg agctgtacat atggcaagag cagtagcgct aactttgagt
    14401 ggtcagccaa ccgcttacga cctcagacaa aagataacag cagcagtcat tatagactac
    14461 tttttaggaa ctgtagggct gacagaagat gaagcgccat tcttggaaca aaataccggt
    14521 tcgtgttcag gagaatttga tctatttcca caatacgacg aagaaaacaa aacagtaaat
    14581 gcaaagctga tctaccatcc ggatacatta gaaataattg gcggacagct gataagccaa
    14641 gaattcttat tatcagattt gaacctgctt gcggatatcg tgaaacacaa aactacgatt
    14701 ccacagctag cagttgagga ttttggattt ctgtctgaat acacctctcg ttttcactac
    14761 ctcaatgagt tagcttttaa agtactagct aagagagcaa atagcaatag agtagataaa
    14821 agactgtgag aaatatcacg gtcttttatt gtgtggggat ataataaata ttaatcaatc
    14881 gagaataaaa aattcatata atgaaatagc ggaagaattt tttgagcata atattcgcca
    14941 aaaatttatc aagtgataaa attgttgtat aaaatgatta tttcaggagg aggagttaaa
    15001 tgtttttagc attaaatgaa attatgcatt caaagttacg ttatgcgtta gttgcagggg
    15061 tgatgttttt gatcgcctac ctggtatttt ttttgactgg gttagcttat ggcttagctc
    15121 aagataatcg aacagcagtc gacaagtggg aggcagattc gattgtgctt tcgaaagatg
    15181 caaattcaaa tctagggatg tccatgatta ctaagaagat agcagaagaa gtcgaaggtg
    15241 ggaaagtggc gtatcttgcc caaacacctg gagtcgtgac tagtaaagac agtacagaag
    15301 aaggaaaaat caatgttagc ttcttcggta tcgataaaaa tcaattcatc atgcccaatc
    15361 ttgttgaagg aaaagctttt gataacgatg atgaggcagt aggcgatatt agtttgaaag
    15421 aagaatatgg tctagccata ggagatacag ttaagttatc tggtagtgac aagacgttta
    15481 aactaactgg ctttacggat catgccaaat tcaatgtctc accagttctc tatacaacca
    15541 tcaatgctta ccaagaaatc cgcttcgaaa aagaagatac aagtgaaaat gcacggatta
    15601 acgcaatagt tgtcagaggt aaaatcagta atttacctga agatttagaa cagatcaaaa
    15661 tttctaaatt catcaatgaa ttacctggat ataatgcgca agtattgact tttggattta
    15721 tgatcggatt tttgatcgtt attgcggcta ttgtgatcgg gattttcatt tatgtactga
    15781 cgatgcaaaa gattaatatc tttggtgtaa tgaaagcaca agggatcaca ggaggattta
    15841 ttgcgcgttc tgtagtggca caaacattca ttttatcatt tgttggtatt cttcttggtc
    15901 tattaggaac agtgggaaca tcccttgttc tacctgatgc ggttccattc caaagcaatt
    15961 ggctgttttt tggcgtcatt agcttgttga tgttagtagt agctgtgtta ggcgcactat
    16021 tttctgttcg gacaatcgta aaaatcgatc cgttgaaggc aattggataa gaaggaggaa
    16081 gaacatgaaa gcaatagaat ttaaagaagt agaaaaaagt ttccaagatg gcgaccaagt
    16141 agttaaagca ttgaaagaaa caaccatgag tatcgataaa ggggaatttg ttgcaatcat
    16201 cggtccttct ggttcaggta aaagtacttt tttgactttg gcaggcggat tgcagacgcc
    16261 tagcagtggc tctgtattta tcaatgatca agaattcagt aatcaaaaag aaagcgaacg
    16321 cgttaaacta cgttttaaag aaattggctt tattttgcaa gcttccaatc tggttccttt
    16381 tctgacagta aaaaagcagt tattattagt agataagatt aaacatgaac atcgtcaaaa
    16441 agaagcaaac gaattatttg agcagcttgg cgtggataag ttgatcaaca agtatccaga
    16501 agaactatct ggtggagaac ggcaaagggt cgcaatcgct cgtgcattgt acaatgatcc
    16561 gtccattatt ctagcagatg aaccaactgc tagtttggat tcagaaaagg cacgagaagt
    16621 agtcgatatc ttggcaaaag aatcaaaaga caaaaataaa gcaacgatca tggttactca
    16681 cgatacacgg ctgattgaca aatgcgatag aatatttatg atggaagatg gtgtattgaa
    16741 agaaaaagaa taaccaaaaa gcaggtggaa aaatggtcca tcgatacaac aaagatacac
    16801 agcaaaaaat tttgaaagaa gcgactgact tgtttatgtc caagggatat ctcggcactt
    16861 caacaagaga aatcgcacaa aaagttggga tcacccagcc caatctctat cattatttcg
    16921 gtgataaaga aaaactatat acggcagttt tagaaaacca cttaaaagat gttggaaaag
    16981 ctttgagaga aatcgttcaa acaagcgaaa cgggatttca agtaaccttg acaaaaatgg
    17041 cgcagttttt gattgagaca catctggtcg atttgtttct gatgcttcac gatcttgaaa
    17101 gcaatctttc aaaggaaaca agagatcatc ttttctttct atggaagaaa aattatcgtg
    17161 aaccttttga agaaatcttt tcagcaaacc aatctgtgct aagaaatggg atttcaaaag
    17221 aaatcgcagc aaggcatttt ttcttagtgt tagcacctta catcactcgg tcgaaaagac
    17281 ctgtggaaga accgctaaat gtggcgcaat tgatcgattt atatttgaat ggtgtattag
    17341 gagaagcgta aagctgttat atagggagaa aatagttagg tgaagaagca agatatgacg
    17401 aagatcgtta tatcttgctt ctttatatag gtagtttttc ataaagacaa atttgttatt
    17461 ctctcatgat tatcagggta tatttttatt tattatgtcg gtgttccagg aagtgtttta
    17521 atttaataac gaagaaatta attgtttgta gaatgaagga aactatttat tgggtagatg
    17581 aatcaccacg aatagtcaaa aggagatttc aggatatgcc aaaaatgaaa aaaatcattt
    17641 tagcagtaat gttattttct acggttatat cttttacagc cccttttttg cttacttaag
    17701 ctgattttaa gttttggccc ttagtctgga tctacgaggt gagagtcaag aatgaaaaaa
    17761 ataattggag cttttgtatt tgcaatcatt atcattatta tctgttttca aatagatgtt
    17821 tttggtcaaa aaaagatagt tggacaaacg gtcagcagta cgaacagtac ggttacaaag
    17881 acaaaggaat catttgatga tacagaacaa gagacattaa tcaaaatcgg aaaaaatgac
    17941 cgtacactat atacagatga ctcgctaact accccacttg caactataaa cggcggagag
    18001 ctggcggagt ttctttctga aacaaaaaat gcttatcaga tcaagacaaa tgatggctat
    18061 actggatatt tagccctcga agatggaacc aaagtcacaa agaatataca aacaaaaccg
    18121 gaagagctat ctgatgcagt gattgtatta gatcctgggc atggcggaaa tgatactggg
    18181 gcattaagca atgatgaaca aacagaagaa aaagatataa cattaagtac agccataaaa
    18241 gtaaaaaagg cgctagagga tgctggagca acggtttatt tgacccatac tacagatgaa
    18301 ttagtacagc ttggagatat atgcgactac agtgaagaaa aaaaggcaga tgtctttatc
    18361 agtttacacg cagactctac ggaatatgcg aatgaagcaa ctggaatcac gacatattat
    18421 tactatggac aagaggaaac attagcacag acaattgctg actccttcac tgatctgcct
    18481 ctggattcaa gaggaatctc cactgggaac tatcaagttc ttcgagaaaa tcttcaacct
    18541 tctattttaa tcgagatggg ttatatgaat aatgatagtg atttaaagga attagtaaca
    18601 gacagttatc agcagcagat tgctgcaagt ttgacacaag cattgaccac ttattttcag
    18661 taataaataa gcccagccaa acaaaaatag ctcctcatat ttttcgtttg gccgggctta
    18721 ttatcgcaga tgcaagcttt tgaacaccgt ttattttttt agtagcttca aagctttttc
    18781 tgtatttgca aagtgaagtt tggcatattt ttcaagcata ggcatgccgc ctttctccaa
    18841 tagttttgcc gctacttggt cagatttcgt tccagctcct gatggaaggg tgattccagc
    18901 ttcagctgat gctttgtgta actcttccaa aaagctggca cgactgatga tagaagcagc
    18961 agcaacagct aaatgatatt gttctccttt agtaacgaag tacagttttt cttgtaattg
    19021 atttttttct aaacgcgcat attttttaaa atttgcttcc ggcgtaaact gatcgatcaa
    19081 aatcgcttct ggtttttctg gctcgatttt ttttagcagc aaatggatcg cttgattgtg
    19141 caaagcgact ttcatccgaa cggcattgta ttttggttgg atctcattgt atttttctgg
    19201 agataagaca agcagtttat aggggatggt tttttttaag atgtcagcaa gctggatgat
    19261 ttggctatct tttaactctt ttgaatctct aacaccaagt ttacgtaatt ctgcaagctg
    19321 atcacgtttc acataagcag cacatactgt tagcggaccg aaatagctgc catttccgac
    19381 ctcatcacta cctaaaacgg ataattgact gatatttttt ggcaaagaag aggctgtttt
    19441 tgctggcttg gcttgtttat cctgtgcctc cccccattta tcagcttcta ttgctgcatt
    19501 cgtaccttga aacatcactt ttccggatgt ataagcggta atggtcgtcc cgtctttttt
    19561 tgcagcaaag ctagtataag gaatctgttt atttaacaaa taagagcgat agtatgcttt
    19621 catttgacta agttggtcgt ttgttgcttt gataatgacg ttgctcataa aattctcctc
    19681 gtttttatac ataaaactat accgcaactc acgacttttc gttttctaag agattgcgag
    19741 acatagcatt tttttaaagt ttatcatata atagttaagt atgtgaaaaa tatttgtgga
    19801 gaacggtgaa agaaccaact tcatggtaca ctaaataaaa ctttcatcaa ataggaggaa
    19861 atgattcgta tggcgcacga aaaaacacgc tacaaagcgg tgattgccaa ccaaacatat
    19921 actattatcg gacgggaaac caagcatcat atggatatcg taacgaagct gatcaatgaa
    19981 cagttagcag aattgaaaca attatcacca caaatggata atgaacaagc agcaatcttg
    20041 atggctgtca atgcgctttc ggatcaattg aagaaacaag aaagaatctt ggagctggaa
    20101 gaagaaacag cagaattaaa gaaaaaaatg atcaaattta cagagcttga aaatcgtgtg
    20161 aaacgcattg aagcaatcga gaacgaagct cgggaagtat tgaaagaaaa tggtcaagca
    20221 gatcatacca ttaaaaatca tgtggaagca caacagattt taaacgagaa acgaaaagga
    20281 caaattaaac aaaaatcttc taattaagat ccttttatca aaataagaaa aatttaaaaa
    20341 aagttagaag agaaaggaac gtagcatgct gagtttgctg attttatttt tattgctaat
    20401 tgcgtttttt tctggagcac gtcgcgggtt tgctttgcaa atcatattcg cgattggata
    20461 tgtattgtca tttattgctg cccagcattt ttacaaacca ttagcaagtc atttggaatt
    20521 atacattcca tacccagctg tcacgccaac atcaaagtta gcattttttg atcaggtatt
    20581 tgcctttcac ctagatgaag ctttttatgc aggaactgct tttctgatta ttttgctaat
    20641 tggctggctg cttacccgat ttgtgggggt ttttgtccat ggattgacgt atgtgccgat
    20701 cttgagacag gtagactgga ttgcaggagg catcctgtca ctaatcatgg cttacgttac
    20761 tatatttttg attttgcagt tacttgcctt tgttccatta gatgtggtcc aaaatcaatt
    20821 cggcgagcat agtttcgctc gctttatcgt tgagagaacg ccatttctta ccaacaagat
    20881 gtatgagctt tgggtaacga atattttgaa ttaaggaaaa tagtgctgga aaatatttcg
    20941 ttttttgtac agagtagatt atttaagaag gctgcgtagc gtatgtccgg cacagctctt
    21001 ttttcatagt gaaagataag gtgataaaat gaataaccga atccttgaaa cattggaatt
    21061 tgaaaaagtc aaacagatgg tcagacaatt tgtagtgact gcacaaggaa aagaagaact
    21121 ggcagaattg gtaccagtga gcgaggaaca aacgatcaca aactggcttc aagaaactga
    21181 ggatggattg aaagtgcaac gtctgcgagg cgggatccct atacctaaac ttgaaaatat
    21241 ccgtccccat atgaaacgga ttgagatcgg agcagacttg aatggagtgg agcttgcaca
    21301 agtttccaga gtattgtcta cgacaagcga attgaatcgt ttcattgatg atctttatga
    21361 cagtgaaatc gaatttgcac gtttgtatat gtgggcagat cagttagtca cgatccctgt
    21421 tttgagccgc cgtttaaagg aagcaatcga tgaagacgga cgcgtgactg atgacgcttc
    21481 tcctgagtta aagagcataa gacagaacat tcggcgaagt gaacaagctg ttcgtgaaca
    21541 gttagatggg atcgtccgtg ggaaaaatgc aaagtattta agtgatgcga tcatcaccat
    21601 gcgaaatgac cgctacgtta tcccagtcaa acaagaatac cgcggtgtat ttggcggtgt
    21661 agtccacgat caaagtgctt caggacagac tttatttatt gaaccaaaac aagtggtgga
    21721 tttgaataat cgtttgcgtc aataccaaat cgctgaacga aatgagattc aacgtatttt
    21781 aagtgaactt tctgctgaac ttgttcccca tcgtcaagaa atcatccaca atgcttatgt
    21841 gattggtaaa atggatctga tgaatgcaaa agcacgattt ggtaaagaag taaaagctat
    21901 cgtgccggga atcagtgaag acaatcatgt cgtcttgaaa caagcaagac atccactgat
    21961 cgatcaggaa aaagtagttt ctaatgacat cacaatcgga aaagactatc aagccatcgt
    22021 cattacagga cctaacacag gtgggaaaac gatcacgttg aagactttag gtctgttaca
    22081 actgatgggg caagcaggat taccgattcc tgcaggtgaa gaaagtcaaa tcggtatttt
    22141 tgaggaagta tttgcggata taggagacga acagtcgatt gagcaaagtc tatcgacctt
    22201 ttcttctcat atgacgaaca ctgtagatat tttatcaaaa gtcaatgaaa aaagtctggt
    22261 attatttgac gagctcggtg caggaacaga tccgcaagaa ggtgctgctc tagcaatcgc
    22321 aatcttagat gatcttggta aaaagtctgc ttatgtgatg gcaacaacgc attatcctga
    22381 attgaaagtt tatggatata atcgggcaaa tacgattaat gccagcatgg agtttgatgt
    22441 ggatacatta agtccaacgt atcgtttgct gattggcgtt cctggacgaa gcaatgcgtt
    22501 tgaaatctct agccgattag gtcttgatac agaagttatt gatgaagcga agcagttgat
    22561 gaatgatgag agccaagatt taaacgaaat gatcacagat ttagagaatc gccggaaaat
    22621 ggcagagacc gaatatctgg aaatgcgtca ttttgtttct gaggcacaag aacttcacga
    22681 tgatttgaaa gaagcttaca gctatttctt tgaagaacgt gaaaaagaaa tggaaaaagc
    22741 aaagaaaaaa gcaaatgaag tcgtgtcaga ggcggaagaa aaagcagaaa aaatcattgc
    22801 tgatattcgt aaaatgcaac agcagattgg gcaaggaaat gtgaaagagc atcagttgat
    22861 cgatgcaaag acccaattag caaatctaca tcaagaagaa actttgaaga aaaataaagt
    22921 attgaagaag gcgaaagaac aaaaaacgtt gaaaccggga gacgaagtgt tggttacgac
    22981 ttacggccaa agagggacgc ttttacgtaa aaacgggaat cagtggcaag tagaaatcgg
    23041 tatattaaaa atgaatgtgt ccgaagacga gctgacgcct gttgctcctc aaaaagagcc
    23101 gacacaacga gttatccatg ctgtacgatc tgaatctagt agtcacgtgc cgaatcaatt
    23161 ggaccttcga ggaaaacgat acgaagaagc gctaagtgag gtagatcaat atttggattc
    23221 tgccattcta gctggttatc ctcaagtgac tattgtccac ggaaaaggaa caggcgcact
    23281 tcgcaaggga attactgatt atcttaaaaa ccatcggagc gtcaaaagct ttgagtttgc
    23341 accggcaaac caaggcggaa atggtgcgac aattgttaaa tttaagtaaa gcttactaaa
    23401 ggtaagcaga tggttcgcta tccaagtata gaaatgctat actagtcata gattttaaaa
    23461 atggaggtct ttgatatgtc acaagtaatt acagataaga catttaatga agaaacagat
    23521 aaaggacttg tattgattga tttttgggca acttggtgtg gtccatgtcg tatgcaagca
    23581 ccgattttgg atcagttgga acaagaatat gatgaagaag aattcagaat tgctaaaatg
    23641 gatgtggatg aaaatccaga aactcctcaa caattcggta tcatgagcat tccaacatta
    23701 atgttgaaaa aagatggtca agtagtagaa aaagctgttg gtgttcattc aaaagaacaa
    23761 ctacgtcaaa tgatcgatca atatttataa aaacttacag caaaaataag ctgagggtgg
    23821 gactgaatcc agttccgtcc tcggtttttt tgcggttgag ttaaggttat tcaaattaat
    23881 attttttgag tataattacg ttgtcaggct ggattgtttt tttgacagac atgctataat
    23941 aactttaatt gaatatgaag gggagtacca gatgaacgaa cgaatcaaaa acaaattagc
    24001 tttacttcct gatcagcccg gctgttactt gatgaaagat aaaaatggaa cgatcattta
    24061 tgtcggcaaa gccaaaatat taaaaaatcg tgtccgctca tattttactg gtagccataa
    24121 tacgaaaacg gaacggcttg ttagtgaaat cgaagacttt gaatacatcg ttacagaatc
    24181 gaatatcgaa gcattgctct tagagatcaa tctgataaag aaaaatgatc ctaaatacaa
    24241 cattatgtta aaggatgata aaacctatcc tttccttaag ataacgaatg aaaaatatcc
    24301 ccgtttggtg attactcgta aggtactaaa agacaaagca ctgtattttg gaccatatcc
    24361 cgatgtcggt gcggcgaatg agacaaagaa gatcctcgat cgattatttc ctctgagaaa
    24421 atgcaaacct agtcagacga aggagccttg tctttactat catttgggac aatgtctgtg
    24481 tccttattat ttcgacgtag atccgaaagt ctatacgaaa atcgttgatg aagtgaaaaa
    24541 ctttttaaac ggaggacacg aaaaaatcga gtcagagatc catcagaaaa tggaaaaagc
    24601 tgctgaaaac atggagtttg aaaaagctgc agaataccga gaccagatcc gtgccattga
    24661 gacaatcatg actcgccaaa aaatgacaaa tactgattta ctggatcgag atgtatttgg
    24721 ttatgcgatt gataaaggat ggatgtgtgt ccaagtgttt ttcgtaagac aaggaaagct
    24781 aattgaacga gatgtttcaa tgtttccttt ctataacgaa gcagaagaag atttcttgac
    24841 ttacctcggt cagttttatc aggaaaatga gcatttcatt cctaaagaag tcttgattcc
    24901 tgatacgatc gacaagccca gtgtagaagc tttgttagct acgaaagtgc tgcaaccaaa
    24961 acgaggagaa aagaaaaaat tagttgaatt ggcgagtaag aatgcctcag ttgctttgaa
    25021 tgaacggttt gatctgattg ccagaaaaca ggaacggacg atcggagcag ttgaacgttt
    25081 aggaaacgcg atgaatatcc cgaccccaat acgtatcgag tcttttgata actctaatat
    25141 catggggacg aatcctgtgg ctgcgatggt cgtattcatt gatggaaaac cggcaagaaa
    25201 agaatatcgg aaatataaaa taaaaacagt caacggaccg gatgattatg catcaatgag
    25261 agaagtcatc tatcgcagat attcgcgagt gattcgcgaa gggttgcctt tacctgattt
    25321 gatcttgatc gatggaggaa aaggacaagt agatgtggca aaagatgtct tagaaaatca
    25381 attaggaatc gatattccta ttgctggcat ggcaaaaaac gataaacata aaacaaatga
    25441 gttgctattc ggtacagatt tggctgtagt accgcttgag cgaaattcac cagagttttt
    25501 cttactccag cgaatccaag atgaagtcca tcgattcgca atcactttcc atcggcagct
    25561 acgcagtaaa aacagttttg cttcccgatt agatgaaatt gaagggttag gaccaaaacg
    25621 aaaaaaaatg ctgcttaaag agttcaaatc gttgaaaaat atcacagcag ccacgacaga
    25681 agaattacaa gaaatcggac tgccgaaaaa tgtcgcacaa aacgtatttg ataaattaca
    25741 tcaggaatga ggaaagggca ctttacaaag aaagtaaagt gtcctatcat tttatgtaca
    25801 acaaaaagag cgtttacgtt ttgttggtaa ataataaatc gcttacgtct ggtgtctaag
    25861 gatatatgtg atttcttgaa gaaggagtga agaaatgtta gaagtcaagg atcttgttaa
    25921 aacttttggg aactacacag ctgtcgatca tgtctctttc caaatccccg atggaaaaat
    25981 catggggcta attggccaaa acggggctgg gaagacaacg acttttcgtt tgatcttgga
    26041 ttttttgaca caagaccaag gagaagtgtt atggaatggc catcatcttg gggagaaaga
    26101 ttatgatgtc atcggttatc ttccggagga acggggactt tatccgaaag taacgattca
    26161 agaccaactg ctttattttg cagaacttag agggaaatca agaaaagaga ttgaaccaaa
    26221 aatcgacttt tggatggaaa aatttcaggt aaaagggaaa aagacggata aagtaaaatc
    26281 tttgtctaaa ggaaatcagc aaaaagtcca gctgatcgcc acgttaatcc atgaacctaa
    26341 attgatcatt ttggatgagc cattcagcgg gttagatccg gtaaatgctg aattgctaaa
    26401 agatggaata ttggaattga aaaaacatgg ttcatgtgtc attttttcta gccacaatat
    26461 ggataatgta gaaaaaatct gcgatcattt gatcatgttg cgaaacggaa aaatggtttt
    26521 gaatggaaaa gtacatgaga ttcgtgaatc atttggccgt acgaagttat tcttggaatc
    26581 tggtttaagc caacaggaag tagaagaaat cgaaggcgtg aaaaaagtga tccttcatga
    26641 agacaatacg ttagagatta ccttagaaga tcctgaagct gggaaagaaa tctttactcg
    26701 tgcgactcag ttcggctaca ttcctatgtt taaccagcaa ccgccaactt tggaagagat
    26761 tttcaaattg aaagcaggtg aaatcgatgc gtaagttttg gattattacc aaagatgtct
    26821 atttaaaaaa tgttaagtcg atttctttct tgatcatgat attagtccct tttatcatgc
    26881 tgggtatcat ttatgtagca ggaaactttg ctcaacaaaa tagtgatgtc aataaaatcg
    26941 gcgtattggc tgataatgag caaatcagtc agcaaatgag ccaagtcaaa acagatgatt
    27001 ttgagttcaa agcagttgat tctgaagaaa aagcacaaaa agagctttcg gaagaaaaaa
    27061 tcgatgcgta tttagtagtc tcaactgaga atgataagat aaatgggatg ctttatagcg
    27121 aaaattcatt aggacaaagt acacaactac tgatacaaca acaactgact ggcttgcaat
    27181 cgatgcttcg agcgagtcaa ttaggcattt caccagaaga agtagctagc ttgagccaac
    27241 aagcaagttt gactcgacaa aaagtcaatt ttgattcaaa aggaaaaatg acagtcggag
    27301 aagataactc gacagtccaa tacgtcgtaa gttatgtagc aacgattgtc ttgttcatta
    27361 ttattttgac gtatgcgcag atcattgcac aagagatcgc ttctgaaaaa ggcacgcgga
    27421 tcatggaagt gatcctgtcc agtacgactg cacaaaagca tttttacgga aaattaacag
    27481 gtgttttact tgttgcatta acgcaaatgg cattatacgg tattattttt ggtataggat
    27541 acagtcaatt caaagatatg gaaatggtca aaaatatatt agacggtatc tcattggata
    27601 acttgattgg accattcttg tggtattctc ttctattcat gatctttggc attttgattt
    27661 tttctgtttt agcagcttta tgtggctctt tggtcaacaa agcagaagat acagcaaaag
    27721 caattttgcc agtgacttat ctatctctag gcggatacat gcttggattg atactaggag
    27781 cttcagatcc aaacaatatc gttattcgga tcacttcgta tattccattc ttatcttcat
    27841 atattatgcc ggttcgctta gcaaatgaga cagtcggtat gggtggagca ttgatttcct
    27901 tgttggtact tgtagccgta acattcttat tgatgatctt gtctgcaaac atgtacaaat
    27961 cgaatgtact cgtttatagc gaaggcggat tatggagttc attgaaacaa tcgatttcaa
    28021 ttatgaggaa tgaacgaaaa aaagcataaa acaatcctaa aatacagaag gaagctggac
    28081 atctattgtt cccagcttct ttttgtatag acctatttta tttattttac tatattggat
    28141 atatattcat tgaaaatagt gtataacaac tttataatat tgagtatacc aatttttgga
    28201 ggcgttttaa tggaccgtta tttagattta ctttcagaaa aattcccctc aacggaggat
    28261 gtcatcacgg aaatcatcaa tctcgaagca attttgcagc ttccaaaagg aacagagtta
    28321 tttttgagtg atatacatgg cgaatttcct gcttttgatc atattctgcg tatcggttca
    28381 ggaaatctta aagaaaagat caaagacctt ttttctgaac aaatgacgga aacggatatc
    28441 agccaattca ctatttttac ggcttatcca gaatatgcat taacgactga ttggtacaaa
    28501 gaacaagata aatcgcagct gatccatcat ttgatcgatc ttttacggtt tacgacagtc
    28561 aaatataccc ggtcaaaagt tcgaaaagga ttgccgaaag aatatagcta tatcattgag
    28621 gaactcttgt atatcgatga ccgtatcaat ggaaaaaaag actatgtaaa aaaaatcatt
    28681 gaacaacttg ttttgatgaa ggaagaagaa aaatttttaa cgaaacttgc acagacgatc
    28741 caaaaatctg tcatcgatca tttgcatatc gttggagata tttttgaccg aggaactcaa
    28801 gcagccaaag tgatggatcg aatcatggat ttttcttctg tagatatcca atggggaaat
    28861 catgatattt tgtggattgg tgcgtattgc ggctctgagg catgtttact gacactttta
    28921 cggattgcag cacgctataa ttatttattt gaattagaga aagaatatgg gttgaattta
    28981 cgtccattgt tttcttttgc tcatcaaact tatcagaaga atccagtatt tgcgcctaaa
    29041 aacagtaaaa atctatccga aagagagcaa gaagaattag aaaaaatcca tcaggcactt
    29101 tctatccttc aattcaaatc agaacatcag ttattggatc gtcgacctga atttaaaatg
    29161 gacgatcgta aattgctgga aaaaatcgac tatgaagcat caacgattga tttagaaggt
    29221 cagctctatg agttgaaagg aacttgtttt caaacgatcc agccagatga tccaaaaaaa
    29281 ttcttggaag aggaacaaaa agtgattgat agtttgatgt attcattcca gcactctttg
    29341 agaatgcaaa aacatatgac gtttttgatc gaaaaagggg gaatgtatct cacgaacaat
    29401 cagcatgtgc tgtttcatgg ctgtatacct gtagacgaga agggacagct cttagcattt
    29461 gaattagacc aatcttatcg cggaaaagaa ctgctgggct tttttgaaaa acagataact
    29521 gaaagcgcaa aagatctgac tgcaaaagaa gatttagcaa ccgatttgat ttggtatgcg
    29581 tggagtgggc cattttcgcc tttattcggc aagagtaaaa tggcgacttt tgaacgttat
    29641 tttctcacag agcctcatac gcacgtcgag aaaagcaatc cttattatca cttgcgagat
    29701 gaagagtggt tcagtgaaaa aattttagca gaattcgaca caaaagaaga agggtcagca
    29761 atcattaatg ggcacacgcc agtaaaagta aaaaaagggg agtcaccgat caaagcaaat
    29821 ggaaaagtat ttgtcattga cggaggttta tccaaagctt atcaaaaaac gacaggaatt
    29881 gccggttatt cactattatg caattcttat ggtttccaaa tcgtgacaca ttatccgttt
    29941 ttgcctattg aacaacaatt tgcaaaaaaa tccgaccaaa caaatgtgaa aaaagtaatc
    30001 gaacagcaac taccacgcaa actcaatcgt gatacaacaa aaggtatgga actgcagcag
    30061 cagattaccc agctcaaaag gctgttggac tatcgaaagg acgattgaga agaattccag
    30121 tgaacattgt tccatagact ggagactgag acaaaagtcg tgtcgcagtc tctttttccg
    30181 gataaacggt gttcttctgc caactcctcg gtcacaagtc acactattca acaaacatga
    30241 aaagctgttt tttgaaattg ctccttgtga ctcagagttg aacggcaggc tcacgacctc
    30301 ttggtataaa cggtgttcaa aagccagttt ctcggtatta agccaaattt atgcaaaaat
    30361 gtgaaaagcc attttcacaa aatttttctt aatactcgaa actaaacagc tttttcacaa
    30421 ccccctcaga aagtctatta aaattcattc acaaagaaat cgaataagcg ctgttcagat
    30481 ggatgtacac ggtgggtaag ttccggatgc cattgaacac cgaggatttt atgcatatca
    30541 tctttgcttt gaaccgcttc aatgagtcca tcgttagaaa aagcgatggc ttttaataaa
    30601 ggtgaaagat ctttgactgc ctgatgatgg taagaattca caaaatatgg atcggggaga
    30661 aggttgctta acaaactgtc tgaaacaatc ttgacttcgt gagtcgtaaa ttgcggggca
    30721 gtgggctgtt gttcatgttt tactgaccac tttggatata atgaaagatc ttgataaagt
    30781 gtaccttcca aaacgacatt caatagttgg agtccccggc agactgcaaa aattggtttt
    30841 ctttgtttca atgcttccaa gatcagtgcc tgttcaaatt ggtctcgttg aatatttgtt
    30901 tccgttagct ttggatgagg atcttccatg taaagttgtg gactgacatc ttgaccacct
    30961 gcaagaataa gtttgtcgat ttgtccaatc agttgaggag ctgaatctgg agacatgact
    31021 ggcagaataa gaggcaatcc ttgagcatct aaaactgcat ccacgaatcc ttgcggtgta
    31081 tagctcactt gatttccttg gaaagtatct gttgctcgaa tcagttgatt tccggcaatg
    31141 ccgatgattg gtttcatttg tattccccct aaagtagact tattgtaaca aggatttaaa
    31201 aaaaattaaa ctatgtaaga cttgccccta tacttatctg ttcttgctgt gttactatct
    31261 gtaaagagaa atttcgtgtg aaattcatga cgatagttga aaatattgct taatttgtta
    31321 taataaaaag taagcagaaa taaaaaggtt gggcgtaagc ttcaaggatc tagttcttca
    31381 aggggtgaga aggacatttt attgaagggg cctgcctata ctaagttatc tttagaggta
    31441 catactttca atgaaaaaag aaagcatgta cctctttttt aaatcgaaag gaagtgaagc
    31501 aagtgttaga agctttggaa caaatccgaa aagcagaaga agaaaatgaa aagcgtgctc
    31561 aaacactgcg gcagcagctg aagatctatg caacagaaaa agagcaggaa ttggaaacga
    31621 tccaaacaaa ctatcgacaa caactaaaac agttggtgga agaaaaagaa caatttgaaa
    31681 tacaagaatt agaaaaagaa aaaatgaaat tgaaagcaga agcagacaag gtgcaagcaa
    31741 ctttgaaaga tcaatatcaa aagcatcaga gtcaagcgat cggtgcgatc attgaaaggg
    31801 tgaaagaaac ttatggccgt cactaagatg gaaaaagtga ccctcatttc agataaaaga
    31861 aatcaggaga ggattttaca agcagtacaa ggaatccaaa acgttgaaat ccgggatctg
    31921 tatcaaaata gaacaaacaa ccagtgggtg gagaagtatt ttccagatac cacgattatt
    31981 gataaagaag caaaattaag cgctttaggt aatcggttga aagacatcca agaagctatc
    32041 caattcatac aacaccacgg cgatagccgt caaaagaaac tccatttgaa acgtcaagaa
    32101 ctttccttac aagatttgga agccaattat tccgaagaaa atttcataaa taaattgaaa
    32161 gaagtccttg atttaaaaga aaagtgggaa caactaactg aagaacgtga tcgtttagaa
    32221 gaagaggaag aatggcttct tcattggcaa cagctggata ttgctccaag tatgtatgca
    32281 agtaagacga ccatttttga gatggggact gtgagtgcag caaattttga aagtttcaag
    32341 gaagaactga gtaagcttga tgacgtttat atggaagaaa tagattatac gccaaaacaa
    32401 gtttatcttt cgtatgttgc tttaaaaaaa tcagttgctg ttatagaaga aattgctggg
    32461 aaatacgggt tcaataaaga aacgtatcct tatgaacaaa atcctaaaga aaaactgcaa
    32521 gagaccaagc agcaattatc cattgttcac gagcagcaaa agaagataac gacagcgtta
    32581 ggtcagtgca gtggctatat ccaagaattt gaatgggtag aagaagtcac acttgccgtt
    32641 gcagaacgag aaaaaataaa agaacggttt atccatgcga cttatctgat cgttttgcaa
    32701 ggttgggtag atgcagaaga aaaacagaat ttgctgcatg tgttaaacga aaccgtatca
    32761 gaagaagata tatacgtcag tttcgaaaca ccaaactcag aagagattca gcaggaagtc
    32821 cctactaaat tgaaaaacca tccgcttgtc gaaccttttg aattgctgac tgaaatgtac
    32881 agtctgccaa aatatgaaga agtagatcca acaccttgga tgacaccatt ttatcttgtc
    32941 ttcttcggga tgatggtcgc agatgttggt tatggtttgc tgatgctcat tgggacaata
    33001 ctagctcaaa aactacttgt tctaccacgc gggatgaaac gtttcgtaaa attctttgag
    33061 attctctcga taccatcgat catctgggga ttgatctaca gttcattttt cggacagtca
    33121 ttaccaaaag aactgtttgg catccgcttg cctttcccaa tcctatctac gacggatgac
    33181 gtcaatacga ttttgatttt atccgtgatt ttcggtctga tacagatttt ggttggatta
    33241 tttgtggcag caaaggaaaa tatcaggaga aaagattact tgagtgctgt cagtgatgga
    33301 tttgcctggc aagggatcct aattgggatc gttattgcgt tggttggtgc catgttgata
    33361 aaaaatacag catttgttta ccttggcgct gggctatcga tcattgctgc cttatgtatc
    33421 ttgatcgttc cgattatcca aacgccgtct aaagtcaaag gtgctgccaa aggtgcgtat
    33481 aatctttacg gactgaccgg ctatatcggt gatttagtca gttatacacg tttgatggca
    33541 ttgggtattt caggcggaag tattggagcg gcattcaata tgctagttgc tttcatgccg
    33601 ccagctgctc gattcagtgt agggatcctt ttgatcatcg ctttacacgc actgaatatg
    33661 tttttgacac tgctaagtgc ctatgtccat ggcgcacgat tgcagtatgt cgaatttttt
    33721 gggaagtttt atacaggagg cggacgtgcc tttgatccgc tgaaaacggc ggaaaaatac
    33781 gtcaacatca atcacaagaa aaaaaacaat aaataattgg aggattttta tataatgatg
    33841 gattacttaa ttagtcaaaa tggtggaatg gtatttgcgg tattagcgat ggcaacagcg
    33901 acgatttttt cagggatcgg ttcagctaaa ggtgttggaa tgacaggtga ggcagcagca
    33961 gcattgacaa caagtcaacc cgaaaaattc gggcaggctc tgattctgca attgcttcca
    34021 ggtacgcaag gtttgtatgg attcgttatt gcctttttga tttttatcaa cttaggaaat
    34081 gacatgtcag ttgtacaagg actgaacttt ctaggtgctt ctctgccgat tgcttttaca
    34141 ggcttgtttt caggtattgc ccaaggaaaa gtcgcagcgg caggtattca aattttagcg
    34201 aaaaaacctg aacatgctac aaaaggaatc atttttgctg cgatggttga aacatacgcg
    34261 attttaggtt tcgttatttc cttcctatta gtgttgaatg cctaagcata aaggaggaaa
    34321 agcagatgaa cgccattgaa aaaatcatct ctcagatgaa cgaagcagca gagcaggaaa
    34381 gagcggcgtt agaacaagaa gagcgaatga agatcgatca aaactttgaa caaaaacgta
    34441 cgcaagttga aacagaacat caaaaacaaa aagaaaaaca aatcgaatta ctcgaaaaaa
    34501 aataccgtca gctaaggaat cgccagcaag tagaagtacg acaagaaaat ttgaatgcga
    34561 agcaggaatt tttaagacga ttgtttgcag atgcggtaac tgaaatggaa aattgggatg
    34621 aatctgaaca aatccagttt atcaaaaatg cattgtattc attacctttg acaggaaaag
    34681 tagcattcat tgctggagaa aaatcagcag cctatctttc tcagacgttg ttggatgaat
    34741 ggaacaatga acttcccttt atgatggttt taagtgatga aactgttgct gatcaagcgg
    34801 gttttctgat aaacgatcaa ggagttcagt ataattttct tttcagcagc cttgtacaag
    34861 atatccaagg aacgatgagt tttgagattg ccaatcaatt attcgaataa ggagggatca
    34921 gtgtatggaa taccacgaac taaatccctt gattcgcgga agagagcttg aacttttgtc
    34981 caatgagaca tttgaacgga tgattcaaac aaattctgtc gaagcacttg gtgaaatatt
    35041 gaaatccacg atttacagtc catatattta tgacggatat gaatatgact tcgaacagaa
    35101 tcttttaaag gagcagagcc gtctatttcg ctggttaaag gaatcagcac cggagcctga
    35161 aatcgtttgg atctatacga tgcgttatac tttccataat ctgaaggttt tgacaaaagc
    35221 tgagatgaca aatcaaaatc tggaccattt gtatatcgac gatggatttt attcattaga
    35281 aaccttgaag gatgccattc atacgcaagt ttcaaatgaa cttcctgaaa gcattatgga
    35341 cagtatacga gaagtacgtg attattttga agagtctacc attcttcagg gaattgacgt
    35401 gatttatgat cgacagtttt tgacagagca gcgacggctt gccgataagc taggatatca
    35461 agaattgctg acagaagtca ttgcttttat tgacttgacc aatatcacaa cgatggctcg
    35521 aggaatattg cagaaaagaa catatgggtt catgacgacg gtactttcca gctcgggaag
    35581 tatcgaaaaa gaagtatttt tgaactttgt agataaagat atggaagatt acacgaattt
    35641 tctattagag acagattatg ctgattttct gcgccctgtc atccgtgagg gaaatattga
    35701 tctcgtaaag cttgaacagt tgaaagatga ttatctaagt tcattgtatc aagaagcaca
    35761 aacccaggct ttcggaccac tgccactact agcctttttg aacgcaaaag aggtagaaag
    35821 caaaaacctt cgtttactgg ttatcggcaa aagaagccat ttcgaatcag aaacaatcag
    35881 aaagcgggtg agacaagtct atgacgcata agatcggtgt agttggcgac aaagattctg
    35941 ttttgccatt caaattgttt ggctttgatg ttcgttatgg tacaaccaag caaaccgttc
    36001 gtcaggcaat tgaagaaatg gcaaagaatg agtatggcgt gatttatgtc acagagcaat
    36061 gtgcagcatt gagcccagaa acgatcgaac gttacaagga acaaatgata cctgctatcg
    36121 tattgattcc caatcatcaa ggatcattag ggatagggct ggaagaaatt caaaaaaacg
    36181 tagaaaaagc agtaggtcaa aatatcttat agtatgaaaa ggagatagaa attttgcaaa
    36241 ttggaaaaat cataaaagtc tccggacctc ttgtaatggc tgagaacatg tctgatgcca
    36301 gtatccaaga catgtgtcta gtgggagatc taggagttat cggagaaatt atcgagatgc
    36361 gtggcgatgt ggcgtctatt caagtatatg aagagacttc tggaattggt ccaggcgaac
    36421 cggttcgctc tactggtgaa gctttatctg ttgaattagg accagggatc atttcacaaa
    36481 tgtttgacgg aatccaacgg ccattagata cctttatgga aatcacacaa agtaatttct
    36541 tagggcgcgg agttcaattg cccgcattgg accatgagaa aaaatggtgg ttcgaaccaa
    36601 cagtagaagc cggagaaacg gtgagtgctg gagatgttat cgggatcgta gaagaaacaa
    36661 aagttataaa acataaaatc atggtgccaa atgggataaa aggaacgatc aaaacaatcg
    36721 aaaaaggttc attcactatt gatgaaacag tatgtgtcat tgaaaccgaa aatggtgaca
    36781 aaaatttgac gatgcttcaa aaatggccag taagacgtag tcggccaatc aaagaaaaat
    36841 taaacccgga tgcacccatg atcactggac agcgagtgat tgatacattc ttcccagtga
    36901 caaaaggagg agcagcagct gtacctggtc cttttggtgc agggaaaaca gtcgttcagc
    36961 atcaaattgc aaaatgggcc gatgtggaca tggttgtcta tgtgggatgt ggcgagcgtg
    37021 gaaatgagat gacggatgtt ttaaatgaat tccctgaatt gattgaccct aatacaggag
    37081 aatcgttgat ggaacgtacg gtattgattg ctaatacatc aaacatgcca gtagcagctc
    37141 gagaagcttc tatctatacg ggaatcacaa ttgcggaata tttccgtgac atgggttatg
    37201 acgttgctat catggcagac tccacttcac gatgggcaga agcacttcgt gagatgagcg
    37261 gacgtttgga agaaatgcct ggtgatgaag gttatccagc ttatcttggt tcacggcttg
    37321 cggaatacta tgaacgatct ggaagagtca ttgcattagg atcagaaggt cgcgaaggaa
    37381 gtataaccgc aatcagtgct gtatccccgt ctggagggga tatttcggaa ccagtcacac
    37441 aaaatacatt gcgggtcgta aaagtattct ggggtcttga ttccagttta gcccaaaaaa
    37501 gacattttcc ttcgatcgat tggatacaaa gctattctct ttattcaaca gaagtaggga
    37561 agtatatgga tcatatcctt caagctgact gggcatccat ggtcaccgag ggcatgcgta
    37621 ttttgcagga agaacagcag ctgaatgaaa tcgtgcgttt ggtagggatt gattcccttt
    37681 cagataatga ccgtctgaca ttagaagtgg caaaatccat tcgtgaagat tatttgcagc
    37741 aaaatgcttt tgatgatgtc gatacattca cttcaagaga gaaacaattc aaaatgttga
    37801 agatgatctt gacctttggt gaagaaggac gccgtgcgtt gtcgttaggt gcttatttaa
    37861 gtgagatcat ggacggtacc gtatcgattc gtgaaaggat cggacgaagc aaatatatcc
    37921 cggaaacaga attagaaaaa ctagatcaaa ttattggtga aatcaagcaa acgatgcaaa
    37981 cgatcgtttc agaaggaggc atgagcaatg attaaagaat atcgtacgat cggtgaagtc
    38041 gtcggtccat tgatggcggt tgaaaaagtt gctggtgtca aatatgaaga attaatcgaa
    38101 gtccgtatgc aaaatggcga gattcgtcgt ggacaagtat tggaagtcca agaagataaa
    38161 gcaatggtcc aaatattcga aggaacaagt ggtatcaatt tacgtgactc ttctgtacga
    38221 tttttaggcc atcctttaga actaggtgta tcggaagaca tgatcggtcg agtattcgat
    38281 ggtttgggac gaccgaaaga taacggacca gagatcctgc ctgaaaagca tttggatatt
    38341 aacggagaag taatcaatcc agtagctcgg gattatccag atgagtttat ccaaacaggt
    38401 atctctgcaa tcgatcattt gaatacatta gttcgtgggc aaaaattacc agtattttct
    38461 ggctctggtc ttcctcataa agaattagct gctcagatcg cgcgacaagc aacggtactc
    38521 gattcatcag atgatttcgc cgtagtcttt gctgctattg gaatcacttt tgaagaagct
    38581 gaatttttca tggaagattt tcgtcaaacg ggcgcaatcg accgttctgt catgtttatg
    38641 aatttagcaa acgaccctgc aatcgaacgt atcgctactc ctcgtatggc tttgactgct
    38701 gcagaatatc ttgcttatga aaagggaatg catgttttgg ttatcatgac agacatgacc
    38761 aactatgcag aggcattgcg agagatttct gcagcacggc gagaagttcc aggaagaaga
    38821 ggatatcctg ggtatcttta cacgaactta gctactttat tcgaacgagc aggaagaatc
    38881 cgcggactaa aaggatcggt tactcaaatt ccgattctaa caatgccaga agacgataaa
    38941 actcatccaa tccctgactt gactggttat attacagaag gacagatcat cttgactaga
    39001 gagctttaca agagtgggat tcagccacca attgatgtac tcccgtctct ttcgcggtta
    39061 aaagataagg gaactggacc cggaaagaca agagaagacc atgcagctac gatgaatcag
    39121 ctttttgcag cctatgcaca aggaaaacag gcaaaagaat tagccgtagt tttaggtgaa
    39181 tctgctttat ctgatgtaga caagatctat gcgaagtttg ctgagcggtt tgaaaaagaa
    39241 tatgtcaatc aaggattcta cacgaaccgt tcgattactg aaacacttga tctagggtgg
    39301 gaactgctat cgatgttgcc aagaaccgaa ttaaaacgaa tcaaagacga catgctggac
    39361 aaatatctgc cagaagggaa gtgagttctg atggcacgat tgaatgtgaa tccgacccgc
    39421 atggaattga ctcgattgaa aaaacagttg acaactgcca caagagggca taaattatta
    39481 aaagataagc aagatgaact gatgcgtcaa ttcatcctgt tgattcgaaa gaacaaccag
    39541 ctgcgtcaag aaatggaaga gtctatgaca gaagcaatgt ctgattttgt attggcaaat
    39601 gcttcgatca cggaaccttt catcgaagaa ttatttgttt tgccggcgga aaacgttgat
    39661 ttgtctatcg tagacaaaaa tatcatgagt gtaaaagtac ctgtgatgaa ttttgaatat
    39721 gatgaacagc tgacagacac acctttggaa tacgggtatt tgaattccag tgccgaactg
    39781 gatcggtcaa tcgatcggtt tactaccctg cttccaaaac ttttggaact gacagaaatc
    39841 gaaaaaactt gtcaactgat ggcgagtgaa atcgaaaaga cacgtcggcg agtcaatgca
    39901 ttagaatata tgacgatccc tcaattagaa gaaacgatct attatattcg tatgaagctg
    39961 gaagaaaacg agcgcgcaga agtaacaagg ttgatcaaag taaaaaatat gggtaccact
    40021 gactaagtgg tatctttttt taaaagagga aaacgatgat taaacaaagc aaacaaataa
    40081 agaaacgttt gccggctgtt cagcttctcg cattaggatt ttttctcctg attttagttg
    40141 gcggcggcct acttacccta ccatttttta gtaatagtgg gcatgggaca aattttatcg
    40201 atgcgctttt cactgcaact tctgctgtct gtgtaacggg attgacaaca ttgaatacag
    40261 cagagcattg gaacagtgct ggtcaatttt tgatcatgct tttgattgag atcggcggtc
    40321 ttggttttat gatggttccg attctatgct ttgcattgat aaagaagaaa gtcagtctca
    40381 gcacacgtat tatattaaaa gaagcgctga atctagaaga agtatcaggt gtgatgaagc
    40441 tcatgcttta catcctaaaa ttggcctttg tgatccaatt gattggtacg gttgctttat
    40501 cttttgtatt tgtgcctgaa tttggctggt tgaaaggtat ctggtacagt ttgttccatg
    40561 caatctctag tttttgtaat gcagggtttg atttgttagg agacagttta gccaatcacc
    40621 agcaaaatgt ttatttgatc atggtggtat ctgctttgat catttctggt gggttaggct
    40681 tcatcgtatg gcgtgattta ctggaatatc atcagaaaaa gaagatgacg attcattcaa
    40741 aaatcgcatt aaccgttaca ggtacccttt tattaggcgg attcgttgtg ttctttttca
    40801 cagagcgcaa tggggcaacg ctagtggaag ggaatatgtt tcaacgattg gcaaacacct
    40861 tttttatgag tgtgacacct agaacggctg gatattattc agttgattac ctccatatga
    40921 gccatgcagg tctgatttta acgatgtttt tgatgtacat cggcggaaca tctgggtcga
    40981 cggccggcgg attgaaaaca actacgttag gtgtgttgct gatccagatg cgttcgatgt
    41041 tgaaaggacg tacgagagcg gaagcatttg gccgtaccat ccgacaaggc gcagtgttgc
    41101 gggcacttac tttatttttt gttacgttga cgttgtgtgt agtcgccatc atgattttat
    41161 cggtgactga aacgatacct aaaacttctg gcatcgaata tattgctttt gaggtcttct
    41221 ctgcgtttgg tacagtaggt cttacgatgg gattgacgcc agacttgact gcaataggga
    41281 aattgatcat tatagcgctt atgtacattg gacgagttgg tgtattgact gtggtcttct
    41341 ctctgatgac aaaagcacaa agaacacaat caaaatacaa atatccagaa gaaagtgtca
    41401 tgattggata atttcatctt ctgacagaaa cctagtgatt tagtaaaata agaaaataaa
    41461 ataatttttc ttgcttcttg gatactttaa gtgcaaaatg ttcgtttatt ttttgaggca
    41521 ctacccgttg ttgaacctcg ggtagtgcct cttttttatt gaaaggaatc aataagattt
    41581 gattccttta tttatcaata ggttataatt catatttttt tattttttct tttacgatac
    41641 ttagtccaga agctaaaatt tcaaggttat tagaggatag ggaaattcga acgaatgcat
    41701 ctggttgcgt acgtgtagta aagcgtctgg aatgataaag tcggataccg ttagcaagaa
    41761 agtcattctc aattatctta gggtcaatct caggatcaac tggaagaatt cgatagtaag
    41821 ggacacgatt cgttggtttt tctactttga aaagagaatc aaaaagctga ttggctcttt
    41881 ttgtaagact taatttagtt tctaagatcc tatttgcttc atttgaatgg aggatttgag
    41941 tgatgacttc cacatctaat ccagaagttt tcacatttat attaaaaatt gcttgttcta
    42001 tcttgctttg gacatgtact ggaactacaa gataagcaac tcgcaatcca gaacaaataa
    42061 attttgtcat tccagctaag tagattgttt ggttaggtaa taaattttgg aaaggaggaa
    42121 tgatcgtatg ttgatagtaa gttgttaaaa atgaatggat atcatcttca ataacccata
    42181 gaccttcttt ttcaatcact tcggctaatt gctctcgtct tttgtgagag atttgaaacc
    42241 ctataggatt attacaagaa ggcataagaa agacaccatg aatcttcttt tttctacatt
    42301 cctgaatcaa tatatcaggt cgcattcctt gctcgtcaaa atcaattgga acgatctcta
    42361 aatgatataa ctgagccaat tcaatgaaat tagcgtatgt atatcggtct gttgctattc
    42421 tatcacctgg agagaaaagt gcagaaagtg tgatagccaa tccattttga acaccggaaa
    42481 caatagatag agattctaag gacggaatga ctccttgagt ttttaaccaa tttgctgcag
    42541 tagtcaattg aaaatttgtg cctttgggat cttggtaatt aagcaaacca acaagatttg
    42601 ggttattact agttgattga ataaacggga caacgaattt attacattct tcaaaagaac
    42661 taaccagacc aaaatcaatg atatgttcgg ttacttcatt ggtagagatg gtgatggact
    42721 caaagacatt gggagaaata aatgtgccac ttccaatatt cgtatacagc aaacctttct
    42781 caattccata tttataagcc ttgccaacgg tagtaaaatt taaatctaaa taatcagcta
    42841 gctctctttg ggagggtaac tgagtgtttt tctgtaattt attctttaaa atatcttgtt
    42901 ctaattgttg aatcaacgat cgataataag gacgcttcaa tttttgtttg tctggtcgcc
    42961 aagttaacgg gtaattgtca taagaattaa taggcatttt ctccactcct taaaattgta
    43021 taccatacaa ttttaccatt gattgtattg attttagaag ttaatctttt gtgaggaggg
    43081 aattgtctat gaaaattatt aattttgagg aagtagtagc ttcttttagt tttgaagaag
    43141 cgattcaagt aatgaaaaaa tgtttttttg attatgaaag tggtaaaatc agccaaaatc
    43201 ctcgattggt ggaaatttta cctgacggaa aaggcaaaaa tatgtttgcg atgatgcctg
    43261 cttatttggg ggagaacaga tattttggca caaaagtcat taccgctttt ccggataatc
    43321 atcagtatca tttaccttct catttaggag agattttctt gtttgatgct caaaacggac
    43381 tacccaaagc attgataaac gcaaatgcag tcacctggat tcgaacagct gctgtatctg
    43441 cgctggcaac agattactta gcaaatccgc atgcagaaac acttgcttta attggagctg
    43501 gtcaacaagc attgtcgcat ttgactgcga tttctaccat tcgtcccatc actacagtgt
    43561 ttgtttacga tattttagaa gaaagacgaa atacttttat cgctaaagct aaaaaacagt
    43621 atcctaaaat aacgtttata aatgcaatat cagtagaaga tgcagtacgt ccagcggaaa
    43681 tcatttgtac gttgacctct agtaaagagg catttcttca aaaagagtgg gtaagggaag
    43741 acgcacatat caatgctgtg ggcacattta ctcctgatac aagagagata agtacatcgt
    43801 tgatggaaac ttctcaaatc tatgtagatg attactcagc tgccttaaca gaaagcgggg
    43861 acctgcttat agccatggca gaaggagatt tagaggaatc ttgtattgtt ggtacattag
    43921 gcgaattagt ttctgagaaa aaaacatttt ataaaggaga atcgaggccg acgattttcg
    43981 acgcagttgg tctagctatt gaagatcttt gttgtgcaga atatatttat aacaaattag
    44041 agaaaggggc tttaaaatga acttagatta ttacgtagtt gatgcatttg cagatgaggt
    44101 gttcaaagga aatccagcag cggtttatgt gctagaagaa tggctgccag aaggtacgat
    44161 gcaaaaaatt gccattgaaa acaatttatc tgaaacagca tttacagtga agaaaaacca
    44221 agaatttgag cttagatggt ttacgccaga tcgagaaatc gatctttgtg gtcacgcgac
    44281 attagcaaca gcatttgttt tatttaacta ttacaaaata cctgatgaaa cgattaaatt
    44341 ttctactcaa agcggtaatc tatttgtgac aagaattaaa gattattatt acatggattt
    44401 tcctagtatt atgccgaaaa aagtgccgat attgtctgaa tatgaagaag cgattggggc
    44461 taagattaaa gaagcctact tagcacgtga tttatttttc gtattagaag atgaaaaaac
    44521 ggtggctaaa ttgcagccag attttacagc tatcaaaaat tttgaattag gaataggagt
    44581 catcgtgaca gcagaaagtg tgcaaaaaga ctttgtttct agaaccttct ttccaaaatt
    44641 aacaatcaat gaagatccag tatgtggatc agcacattct aatcttattc cttattgggc
    44701 agaaagaatg aataaaacaa aattgtcagc ttatcaaatg tcatcaaggg gcggggatct
    44761 agaatgtgaa ttaaaagaag atcgtgtgat aataggagga aaagcagttt tgttttctaa
    44821 aggtacctcg tttatttgat ttctttcaaa tgaattaaaa ataaattggt ggagagtggc
    44881 aaccttatag ctacaatggt tgttaaaaaa agacgcaaac tttttcaatt taatgaaaag
    44941 tttgcgtctc attttaatta ttggtgtttg ttttttattc aatcaagagt aaaatgcccc
    45001 atactaacta tcctcggatg acttcgattt tataaccatc agggtcaatg acaaagtagt
    45061 aagaaggcgc agtgccaggt aatcctttta agtcagtaat ctcaagacca gcagctttat
    45121 gttgctcgtg taatttttct agatcatcag ctgctatagc gatatgacca tagccgtctc
    45181 ctagatcata cgcaccatga tcatagttgt aagtcaactc taattcatag tcatccccag
    45241 gaagtgtcaa ataaacaagt gtaaatttgt tttctggaaa atcacggcgg cggctttctt
    45301 caaaaccaaa tgccttttga taaaattcga ttgatgcttc aagatctttc actcgaacac
    45361 atgtgtgagc cattttcata gattcatctc tccttttcct tttactcaat cataacaaaa
    45421 agaagtaagg aaatagttga tttgtgcttg ttcatgagaa atttctcatg taaaatggat
    45481 agaaaataaa actgttaagg tggaaactat tcatggataa accaattttt ggtgaaaaaa
    45541 agcaatttgc tgattatcaa acccgttatg cagcatatat tgtcatagaa agagatcagc
    45601 agattgcagt aatcgaggct ccaaatggtg ctttttttct tcctggcggg gaaattgaag
    45661 gagaagagac gaaagaagaa gcgattgtcc gtgagctgat agaagaaatg ggaattgtgg
    45721 cagaaatttc ttcttatctg ggagaagctg atgagtattt ttactcgaat tatcgtgcaa
    45781 cttattatta taatccagga tatttctttg ttgctgattc ttggaagcgt ataggagaac
    45841 caactgaaaa gaccaataaa atttggtggg tgagccctca agaagcgctt gtgaaattga
    45901 aacgtggtag ccaccgatgg gcagtcgaga gatggatcga aaaaaataaa aactgaaaga
    45961 aagcgagtag atcagctttc tctcagtttt tttatttatt acagtacata ttttttgatt
    46021 gcttcagcta caccgtgctc gtcgtttgat gaagtgatga catttgctgc ttctttgaca
    46081 agagaaacgg catttcccat tgctactcct agaccagcat attcaatcat ggataagtcg
    46141 ttctcgttat ctccgatagc catgatttca tcttgatcaa taccaaggtg ctgtgcgaga
    46201 ttcgcaactg ccgcaccttt acttgcttct ttatttagta cttcgaagta atagggcgca
    46261 cttttgaccg ttgtgtattt atcacggaaa gtttgcggta aacgcgcaat tgctgcatct
    46321 aaaatttctg gttcgtcgat catcatcatt ttgacgatgt tcatgtctgg tgtcatttct
    46381 tcaggtgttc gatattttag cggcatcttg actaaacttg cttcgtggat cgtataagcg
    46441 ctgatatctc gattaggcgt gtagatcgct ttgtcatcga tcgaatggag atgactgccg
    46501 acacggcgtg ccatcacttc gatctctagg aaatcttcat gtgtcagtcc gtgacgggcg
    46561 atgattttac ctgatttcgt ttgttgtacg agtgccccgt tataagtaat aacgtaatca
    46621 ttatcttgaa aaaggttcaa ctcgtttaac tgttcctgga cacctggtaa gggacggcca
    46681 gtgcataaaa cgatcgaaac accttttgca acagcagcgg caatcgcttc ttttacttct
    46741 tttgttactt ctcttttctc atttaataaa gtaccatcga tgtcgatagc gactagtttg
    46801 atagacataa tttcctccaa tatattttaa tttatttcaa tcaatgcgcc attacggata
    46861 tggctggcaa attcttgata agtttcgtca aataaatcat aatgatcacg caaggacgga
    46921 tcaaccattt cttttggaaa gaaaaatcgc tcatctcctt gttcttgtcc cgctaatgca
    46981 gcaacaagct gactaacctg tgataattct atcaaagttc cgtcatttcg caaaatctcg
    47041 atttgtgtgc gatgtctgcc ttgttctggg cgataaaaat cataaggtag atcgtagcta
    47101 gaattcacag cagtgtaata aacaggatta tatccgacct tttctactaa caaagtgagt
    47161 tcttggacta attttgaatc ccggttgcca gaaaaagtag cagatttcag tggtttacga
    47221 ttcaaaaaac gtttagctaa atcatttaaa ataggatcag cagattcaga ccattgagta
    47281 aagtaagtgc ccaagacccc atcatcaagt ttgaggtatt cttctaaagt aaagcttccg
    47341 tcaagaaatg gcagaagtaa ttgagaatgg agttcaaaac tgctggcatc ttcttgatac
    47401 aactcgtgtg cgcgatgaag cagatgctcc aaaattactt ccataccacg ggaaacagga
    47461 tggaagtaca cttgcacata catttgatat cggctaacga tataatcttc cactgcatgc
    47521 atgccactca tggaaaaagc gatcccgcct tcataaggac gaatcacacg taatattcgg
    47581 gtaagatcaa atgttccata ttctgttcca gtgaaataag catcccgaag caaatagtcc
    47641 attcgatctg catcgatctg actagaaatc atttggacaa cttgtgggtt ggggtaagtt
    47701 ttttggatca cactagctac cttttcagga aaaccttctt ctactcggtt aagaatctga
    47761 tacacttctg tttctggaga agtgatgatc tctacagtga tggcttcatg attcgtatgg
    47821 aagatatgtt caaatgtatg agagtaagga ccatgaccga catcatgcaa cagtgccgca
    47881 cataaagtca ccagccgttc ctgatcatcc cagcctccgt tgcctatttt ttcttttgaa
    47941 aaatttcgag aaaagatatc gcagattcgt cttgaaatct cataaacgcc taatgaatga
    48001 gtaaaacggc tatgttctgc tccgtgaaaa gtgaaagaag aagtgcctaa ttgtttaatg
    48061 cgtcgtagac gttggacttc tttcgaattg atcaaatcta agattacttg atgctggaca
    48121 tggatatagt tatggactgg atcacgaaaa actttttcca taggcagcat ttgatattta
    48181 taaggggttg tcataatgta gctcctttat gttattacgt tgttccattc tctggatttg
    48241 gttgttccat tgctccagct ggatttcttt ttttagccag tcggtagaat cctgtaaatc
    48301 acttgcagaa tacagctttt caaaagcttt tgcaaatgct tctttgactt cttttacaaa
    48361 aaggggttgg tcaagcagtt cttcaagtgt tgccattgta gcaggatcca ctgcaggata
    48421 gccatttgta ccaaagtctt cttttaaagc agattgataa aatcgcttca tgacttgccc
    48481 gcgtttttcc tgattaccgt tgacacttaa gtacatcata acagaaatcc catttttgat
    48541 ccgacgctga gcgataccgg caaatttttt gccatggatg cttaaatcat aagttccagg
    48601 acaataagaa tgggtgattt cgaatgcttg tatcggtgcc tttggaaaag cgtatttagt
    48661 caataggagc atttgctcgt aagcgtcatc tatggttatt ttttttgtgt cactttgggg
    48721 gaaaatcaaa gaaatattca aaattccttc atctgatacg atccctaatc cacctgaatt
    48781 tctgatcact ggagcgtaac ctgcatcttt cagtgtttgg atcccgtcac ttagaaaagg
    48841 agttcgaaca tccttcatac ctaagatgac tgtgcagtca tattgccaga aatgtaaaaa
    48901 gatttgctgg tgttctttag aatattccgt taatatatct gttaatgcaa aaggggaaaa
    48961 gtcgtttttt tgataaatgt gctgatctag tcgaatcgca gggttcattc aaccggctcc
    49021 tttgtataaa ttcatatttt ctacaatatt atactctaaa atcaaagagt tgttttggaa
    49081 aaaaggtttt ctgtaaaaat ggacaagttg gttgacaaaa caaaagaaac taggaacaat
    49141 gtagctatga gaagtaaagg agaatgaata atggaattat cacaaggaac accgatttca
    49201 atcaaattgc gtacaaaagt aaaacagcaa ggggaagtgc aagattttta ttttgatttg
    49261 aaagggcaaa tggtgacaat tggcgatacg ctgtacatac gttataaaga gattcaggag
    49321 gagacgggcg atgagattcc tgtaacgatc aaattagttc cagatggtca tgtacagctg
    49381 atccgtgcag gagaaatgcg gatgcgtttg aaatttggct ataaagaacg gttagaaaca
    49441 tcctatcgaa caccatacgg tatgatccag attgctactt ttacgaaaga actgcatgtt
    49501 agtttgaaag accgtcccac agcagggaag gttcgaatcg attatgatct gttcatggga
    49561 ccggaaaaaa tcggcgaata ttatttgacc ttggatttta cagcgtaaat ataaaagaaa
    49621 agtttgattt tttgtgtctg attttgtatg ataaggagta gactgtgaaa ggacgtgtcc
    49681 tgattggaaa ttagtgtatt tgaaggtgca aacaaaagcg aattatcaat gatcgaagta
    49741 gcacacgcga tcttagaaca acgtggcgat gtcatggatt tttctgattt agctaaccag
    49801 atccaaaact atcttgggaa atcagacagt gaaattcgtg attcactcgc acaattttat
    49861 actgacttga atattgacgg cagctttatc tcattagggg ataatcgttg gggcttgcgt
    49921 tcatggtatg ctatcgattc gatcgatgaa gaagtaaacc atggaatgga cgaagaggat
    49981 gaagatactc cacgtcgccg taaacgcaag aaagtcaacg cctttatcaa tgatgatgaa
    50041 gacgcgatcg attacaatga cgatgaccca gaagatacag atctgacaga agaagatgac
    50101 gatgatctgt ttgatgacga tgatgatgaa gatgaagaaa tcgctgctta taattctgac
    50161 ttgcaagaaa tcggagcaga tgacccgaca gatgatgaag aagacttgcc aggaaatatc
    50221 gaagaagatt taagtatcat agacgaagac gatgatgatg aagattatga agaggaagaa
    50281 ttttctgact ctgaaaaaga ataaacatta ttttcttacg agaggttgtg acagagacga
    50341 tcagcctatc agaataagga ggtgtgacac gatttttgtc acaccttctt ttttgtatat
    50401 aaaaatccca agtaaataca taaaaaataa aaaaattgaa acttttagcg caccttgtac
    50461 gtcatattaa gtgaggcaga aaggagtgga gaatgatttt tactggatat aagaaaaaac
    50521 ggcagatcga aaaataccgt cacctgctga atggactcat cgaaactgat tatcaaaaaa
    50581 tgttccgtat cacgatgaat tacgtacatg ataaagaaga ggccttagat gtgatgcaag
    50641 atagttttca taaagccctg aactattttg aaaaagaaaa agagatcgag cattttagtg
    50701 catggtttta tcggatattg atccgcacgg cattagatag ttggcgcaga caaaaaagga
    50761 cgcctgtgga cttatttgaa attcaagata tcccccaaca gttaccttta gaaacttccg
    50821 ttgcagagct ccatatgatt ttagataaaa tagacagtcc ggaaaaagag attctgatcc
    50881 tctacttttt tgaaggattt cgtttgaaag aaattgcgac tatcttggat atgaatgaaa
    50941 acacagttaa aacgaaaatg taccgctcat tgaatgcttt acgtcaaatc ctagaatgaa
    51001 ggagagaaga gtgccatgta ttcccaaaaa gaaaatttaa aaaaactaaa gaaaacttat
    51061 aaagaacaag caattcccaa agggcttaaa gaggagatcc gccagcgttt tattatcgaa
    51121 gagcaatcat ttataaaagc aaagcggaga aagagacgtc tccaagggtt cggagtatct
    51181 ttggctatcg taatgattac aacaagtagc cttcttttta atagtcaagt tcgaagcttt
    51241 gcagaagatt tacccatctt aggatcagtc attgaattga tcttaggcga acgctttact
    51301 gatcgatctg aaaaaatcga tattcaggta ccgaagatca atacacaaaa tgagaaagaa
    51361 aataaaacaa ttcatggatt aaatcaaaaa tactttcgcg aaggacaagc agattttgaa
    51421 aaagctgaaa aagaatatgg aaattttgaa acggatcatt accaagtttt gggagattat
    51481 cagaaaatcg tagacgataa ccggtttctc gtgattgaaa ggcagatcac ccaaacagca
    51541 gcagatagcc atgttgaaaa aagatacgac acaatcgaca agaaaaacag tgtccagctc
    51601 tcacttccac ttttattcaa agatgacacc tatctatctg ttttgacaaa agaagtcaaa
    51661 cggcagatgg ccgaacaagt caaggaagat ccatctaagt actattggac tgagcaagat
    51721 attcaagaag ggacgataga aaaaccaaca cttgttacgc ctacacgaag tttttatttg
    51781 aacaaagagc atcaattagt tttgactttt tctcaatacg aaattgctcc tggttatatg
    51841 ggtacaccag aatttgtcat tcctaagtcc gtgacaaaaa cgattttggc atcggaagat
    51901 tatttggatc attagacgag aagtagttgc gactagcagt ttcaattttc aagtaagtac
    51961 aagtaaataa taagaagaga aaaagagaaa gaagagatat agtgaaaaga aattatttag
    52021 ttatcagtat tattgcttta tccgtgcttt tgtttttcga aattacttcg gtggcctcct
    52081 tgatcaccga agtaaaagga caaacacact cttcggagca ttcgtcacaa tctttcaaac
    52141 aatcagaaca atcaaccatt aaaagccaat caactgaaac agctaacgtc aaagaagcca
    52201 ttcaagaatc agcggaaaag gtacaaagtc agtcatcaca atcaacacaa gacagtacaa
    52261 aaacgagccg agatccggct gtcaaaagcg tcgcaatcag ctttgatgat ggaccaggag
    52321 cgaccacaac accgcagctt ctgcgaatct taaaagaaaa aaacgtgcat gccacttttt
    52381 tcgtcttagg agaaaatacg gcgcagcatc ctgaaatcgt gaagcagaca gctgaagcag
    52441 ggcacgagat tggcaatcac acatacgatc atcagaatct ggccactctt tctgcccagt
    52501 cgatgacgga ggaagtgacg aaagcagaca ctgagatcaa aaaagtcact ggcaaaaccc
    52561 ccacttttgt tcgtccgccc tatggttctg tcacgaatgt aggagcaacg atcatccagc
    52621 gaccgatcat cgaatggtct gttgattcag aagattggaa gacaagaaat cctgatttga
    52681 ttttgcagaa gatccaagca acagtatacg atggggcaat tattttattc catgatatct
    52741 atcctgaaac gattcgtgcc gttcctcaag tgatcgatta tctgaaagag caagggtatc
    52801 gcatcacgac agttggggat ttattagggc atccaacggc tgtcgagaac tattatggca
    52861 gaaacgatca tcggccagtt cagtaagtga gacaagtatc tttaataaat aacacatttt
    52921 aataagtagt tgaacacata actaccttac ttgcaaaggc ttaacaatat ctatacaggt
    52981 acaacaaaaa actgtccacc aattttcttt ggcggacagt tttcacttaa aaataaagaa
    53041 gcaactattc gtaaattatg ctaaaatagc agtagaacgc gtcctgaggg aatcgaaccc
    53101 ccgtctcaag aaccggaatc ttacgtgata tccactacac taaggacgca agcactggga
    53161 taattgtaac taaacagata aaaaattaca aggggattgg acaaaaaaat gaaatttgag
    53221 caaaattttt cacaaaaaca gcagcagaca cagaaactag ccatgacgca acagttgcaa
    53281 cagtccatcc aagttttaca atataacagt gaggagctgt tggcattcgt tgagaatcaa
    53341 gcaatggaaa atccattggt ggaagttgtt gagccggaat ggcagccaga ttacataaaa
    53401 gcttcttcat cttcttatga aggagaagag acaaattacc taaatcagat tcctgataca
    53461 aaagggtctt tatttgattc attgatcgaa caagtccatt tgaattaccg agatactttt
    53521 ttgaggaaaa tcgttcttta tcttgtagaa tacatcgatt tgaacggatt tttgacgatt
    53581 agtttagaag aagccggaaa agagattgga gctacgccta tccaaatgct cgatgcgttg
    53641 actctgattc agcaattaga accagctgga gtaggtgcac gtagtttgca agaatgtctc
    53701 atgcttcaaa cagaacgaga tgattatgcg ccggaattag cttatatcgt gttggaagaa
    53761 tgttttgagg aactggtgga gcgaaaatgg aaagaaatcg cacaacgttt ttctgttgat
    53821 ctacatgctg ttcagcagat attcgactat ttacaaacgt tgagtccaag ccctggccgg
    53881 attttcgacc gtagcagcga attgtacatt attcctgatg tccgggtatt agtggacgac
    53941 gataaaaatg tacaagttat ctcaaaccga aaaaatcagc caaatatacg ctttcaagag
    54001 agttacttca aacaaatgtc acaacaagca gataaagaaa ctgaaaatta tttaaaagaa
    54061 cggaaacagg aattcgaatg gttgaagaaa acgatcctac aacgtgggga tacaattttg
    54121 cgggttgctc aagtcattgt ttcccggcaa aaagctttct ttatcgacaa ggaacgtcca
    54181 atcaagcctc ttacgttaaa ggaagttgca actgagatag atgtgcatga atccacggtc
    54241 agtcgtgcag tcaacgggaa atatttggaa acagacttcg gtgtatttga attaaaaaaa
    54301 tttttcacta cacgaattcc tacgaatagt acagaacaga cagaagacct ttcagcagat
    54361 acagcgaaga aaaagctgca ggaattagtc gatcaagaag acaaaaacaa gccgttgtct
    54421 gaccagaaat tggttgaatt gctgaaaaaa gatgagatag cgatctcaag acgaacagta
    54481 gcaaaatatc gtgatttatt aggaatcccg agttcatcaa aaagaaaacg ttatgataac
    54541 taatcagtca aaagactaga aaaagtattt cactttttct agtcttttta gttgaaaaac
    54601 gagagcaaaa ctgttagact tacagtcgtg aggttgagat ttccctttat tgatgtgaaa
    54661 ttcgaatagt taatttcttt ttttatcgta tatgggtcgt tttaagtcta cattggacgt
    54721 aaagtgtcca actaaggaga tcgctatgct ggatgaaata aaaatgattg aatctgttgc
    54781 accagatatt atcgaagtgt tgcaagaacg ctataaaatt ttacgaaata tctattggat
    54841 gcagccgatt ggacgtcgaa gtttatcgga aagtatgggg atcacagaac gagtattgcg
    54901 aacagaaaca gatcttttga aaaatctgaa tttgatcgac acctcaaaaa gcggtatgac
    54961 gctgacaact aagggcgaag aagtttatca aagccttgaa aacttcatgg atcagctttt
    55021 aggtacgcat caaaccgaac aacagttggc agaatatttt ggtaaccaac gctgtatcgt
    55081 tgtttcagga aacagcgaag agcagaccaa agtggctgat gcattcggcg aagcgctgag
    55141 cgaagcccta gaccgactac ttccagaagg cgagaatatc atcgctgtga tgggaggaac
    55201 tactatggct gtggtagccg aacaattgtc taatctggaa aataagaaac ggcataacct
    55261 gtttgtccct gcaagaggcg ggattggtga agcgataact gtacaggcaa attctgtcag
    55321 tgcaagaatg gctgctaaag caaacggtaa ccaccgtgca ctttatgttc cggaacaatt
    55381 aagtctggca acttacaatt ctttactcaa tgagccatct atccaagaag tcttaaactt
    55441 gattagtgaa gcgaattgtg ttattcatag tattgggcgt gcattacaca tggcagcacg
    55501 tcgtaagatg actgaaaaag aattagtcat gctgaaacaa gcaaatgctg ttgcggaatc
    55561 ttttggctac tttttcaatg aaaaaggtga agtcgtttat aaggtcccta gaatcggcat
    55621 agaattgcaa gatttggaaa aagtcccgat catcatggca atcgcgggcg gaaaatcaaa
    55681 agctaaagca attcgagctt atatgaaaaa tgcaccaaaa caaacgtggc tcatcactga
    55741 tgaagctgct gcaaatgaga ttttaaaagg ggtaaccctt taaaataaat atttttttga
    55801 ttttcataag gaggaaatct taaatgacag ttaaagtagg tattaatggt tttggacgta
    55861 ttggacgtct agcattccgt cgtatccaag atgtagatgg aatcgaagta gtagcaatca
    55921 acgacttgac agatgctaaa atgttggcac acttgttaaa atacgacaca actcaaggac
    55981 gtttcaacgg aacagttgaa gttcatgaag gttcattcaa cgtaaacgga aaagaagtta
    56041 aagtattagc taaccgcaac ccagaagaat taccatgggg cgaactaggc gtagatatcg
    56101 ttctagaatg tactggtttc ttcacttcta aatcagcagc tgaaaaacat ttaacagctg
    56161 gtgctaaacg cgttgttatc tctgctcctg gcggaaacga tgttccaaca atcgtttata
    56221 acacaaacca cgaaacatta actggtaaag aaacagttat ctcaggtgct tcatgtacta
    56281 ctaactgttt agctcctatg gctaaaacat tgaacgacaa atttggtgtt gttgaaggat
    56341 taatgacaac tatccacgct tacacaggtg accaaatgac tctagacgga cctcatccta
    56401 aaggtgactt ccgccgtgca cgcgctgctg ctgcaaacat cgttcctaac tcaacaggtg
    56461 ctgctaaagc tatcggttta gtaattcctg aattgaacgg taaattagac ggagctgctc
    56521 aacgtgttcc tgtaccaaca ggttcattaa cagaattagt aacagttctt gaaaaagaag
    56581 taactgttga cgaaatcaat gcagcaatga aagaagcttc aaacgaatct tacggataca
    56641 acacagacga aatcgtttct tcagatatcg ttggtatgac ttacggttca ttatttgatg
    56701 ctacacaaac taaagtaatg acagttggcg acaaacaatt agttaaaact gttgcttggt
    56761 acgacaacga aatgtcatac actgcacaat tagtacgtac tttagaatac ttcgctaact
    56821 tataagatag acaaacgtac aagtgtaaat tatagacatg tacatttaaa agcggggaag
    56881 caatcgcgct tcttccgctt tttttgataa taagtttatt caggaggaaa taaaatggct
    56941 aagaaaacag tgaaagatat cgatttaaaa gacaaaaaag ttcttgtccg tgttgacttc
    57001 aacgttcctt tgaaagacgg cgtgatcact gacgacactc gtatcaaagc agcattgcca
    57061 acaatcaact acgttctaga acaaggcgga aaagcaatcc ttttctctca ccttggacgt
    57121 gtaaaaacag aagaagataa agaaggaaaa tctttagctc cagttgcaaa acgtctaggc
    57181 gaattattag gtaaagaagt aacattcgta cctgaaactc gcggagaaca attagaagaa
    57241 gcaatccgca acatgaatga cggcgacgtt gtcgtattcg aaaatacacg atttgaagat
    57301 attgacggta aaaaagaaag caaaaatgat acagaactag gtaaatactg ggcttcatta
    57361 ggcgatgtat ttgttaacga tgctttcggt acagctcacc gtgcacatgc ttctaacgta
    57421 ggtatcgctt caactggtat cccaacagtt gctggattct tgatggaaaa agaaatcaag
    57481 ttcatcggtg aagcagtaga agaaccaaaa cgaccaatga ttgcaatcct tggtggcgca
    57541 aaagtttctg ataaaatcgg cgtaatcgaa aacttgattc ctaaagcaga taaaatcttg
    57601 atcggtggcg gaatgactta cacattctac gaagcaaaag gaatcaagat cggtaactct
    57661 ctagtagaag ctgataaagt ggaactagca aaagaattaa tcgaaaaagc aggcgacaaa
    57721 cttgtcttgc caatcgacaa tgtctgtgca ccagaatttt caaatgatgt tgaaacacaa
    57781 gtaatcgaag gagacattcc tgatggtttg atggctttag acatcggccc agcatcagta
    57841 aaattatttg ctgatacatt acaaggtgca aaaacagttg tttggaacgg acctatgggt
    57901 gtatttgaaa tgagtaactt tgctaaaggt acaatcggtg tttgtgaagc aatcgctaac
    57961 ttagaaggcg caacaacaat catcggtggc ggagactcag ccgcagcagc agaacaatta
    58021 ggatttgctg acaaattcac acacatctca acaggtggcg gcgcaagctt ggaattgctt
    58081 gaaggtaaag aattaccagg actagcagca atcaacgata aataaacgac caagtttgct
    58141 caattctgac gagtaatcga acaaaaggtg aagggagttt tcatgactcc ctagccattt
    58201 ttcaataaat taaggagtgt gttcctcaat gcgtaaacct attatcgcag gtaactggaa
    58261 aatgaacaaa actgcatcag aagcaaaaga atttgctgaa gcagtaaaaa acaaaatccc
    58321 ttcaaatgac aaagttgatt cagtcatcgg atctcctgca ttattcttac aagaattaat
    58381 gacatcagct gaaggtacag aactaaaaat ctcagcacaa aactgctact gggaaaactc
    58441 aggtgcgttc actggtgaaa cttcaccagc agctcttgct gatctaggtg ttcattatgt
    58501 gatcatcgga cattcagaac gtcgtgaata tttccatgaa acagacgaag acatcaataa
    58561 aaaagcgaaa gctatctttg caaatggtat gacaccaatc ctatgctgtg gcgaatcttt
    58621 agaaacctat gaagcaggca aaactgctga atggatcgaa ggacaaatta cagctggttt
    58681 agctgatctt tcagctgaac aggtgtcaaa catggttatt gcttatgaac caatctgggc
    58741 aatcggtact ggtaaatcag ctgacgcaca aatcgctgac gaaatttgtg gagttgtacg
    58801 tcaaacagtt gaaaaacttt atggaaaaga agtatcagaa gcagttcgta tccaatacgg
    58861 cggttctgta aaaccagaaa atattgctga atacatggca aaagaaaatg ttgacggtgc
    58921 tttagtcggt ggcgcaagct tgcaagcaga ttcattcttg tcattgttag acgctgtaaa
    58981 ataattgttg aaaatttgcg aaaaatgcaa gaaatgtttg cactaatgag caaaattaac
    59041 taaaatcgta tatgagggaa atcccttagg aaaaaacaaa ctcaaaggag agacaaaaca
    59101 tgtcaattat tactgatgtt tacgctcgcg agatcttaga ctcacgtggt aacccaacaa
    59161 tcgaagtaga agtatacaca gaaagcggag cttttggccg cggaatggtt ccttcaggtg
    59221 cttcaactgg tgaatacgaa gcagttgaat tacgtgacgg agacaaagct cgttatggcg
    59281 gtaaaggtgt aactaaagct gtcgacaacg taaacaacat cattgctgaa gcaatcattg
    59341 gctacgatgt tcgtgaccaa atggctatcg acaaagctat gatcgcttta gacggaactc
    59401 ctaacaaagg taaattaggt gcgaacgcta ttttaggtgt ttctatcgct gttgcacgtg
    59461 cagctgctga ctacctagaa gtacctttat accactacct aggcggattc aacacaaaag
    59521 tattgccaac accaatgatg aacatcatca acggcggatc acatgctgat aactcaatcg
    59581 acttccaaga attcatgatc atgcctgttg gcgctccaac attcaaagaa gctctacgta
    59641 tgggtgctga agtattccac gcattagctt caatcttgaa agctcgcgga ttagcaactt
    59701 ctgttggtga cgaaggtgga tttgctccaa accttggttc aaacgaagaa ggttttgaag
    59761 taatcatcga agcaatcgaa aaagctggct atgtacctgg taaagacgtt gttcttgcta
    59821 tggatgctgc ttcttcagaa ttctacgaca aagaaaaagg tgtttacgta ctagctgatt
    59881 caggcgaagg cgaaaaaaca actgacgaaa tgatcaaatt ctacgaagaa ttagtttcta
    59941 aatatccaat catctcaatc gaagacggat tagacgaaaa cgactgggac ggattcaaga
    60001 aattaactga cgtattaggc gacaaagttc aattagttgg tgacgacttg ttcgtaacaa
    60061 acactcaaaa attatctgaa ggtatcgaaa aaggaattgc taactcaatc cttatcaaag
    60121 tgaaccaaat cggtacatta acagaaactt tcgaagctat cgaaatggct aaagaagctg
    60181 gctacacagc agttgtatct caccgttctg gtgaaacaga agattcaaca atctctgata
    60241 tcgctgttgc aacaaacgct ggccaaatca aaactggttc tctatcacgt actgaccgta
    60301 ttgctaaata caaccaatta ctacgtatcg aagaccaact tggtgaagtt gcagaataca
    60361 aaggtttgaa atctttctac aacttaaaaa acaaataatt cttttctaat gaagatacat
    60421 gatcgactat tgaaagatag tcgagtatga tcacttagtt aagtaatcga actctctact
    60481 tgctgaaata tcagcaggta gagagttttt ttgcaactag cttctgtata tgatgtttac
    60541 aaagaatggt acaagaaaag atcatccttg aaaaaggaaa gctaacaata actagcatca
    60601 tataagagct tttaaggata gaacagtaga ataggaatct atgagcaagt cctctcgtat
    60661 aaataaaata ggagggaagt agcagcatat ttttcataaa gtggctctct ttcttcattt
    60721 ttactttggt tgctcctatt tgaaaattcg agcacactca aatacaataa aaagaaatgg
    60781 caagggagag gattagatga aaaaagaaga aaaaatcgcg attttacaag agatcatccg
    60841 aattaaatca gtgaatggaa acgaaggtga agtagcagcc tatttgaata agcttttggc
    60901 aaagcatgac ataacaggag agattgtttc ttacagagat ggtagagata atttgattgc
    60961 tcgttaccaa aagggccaat caggaaaagt gttaggccta tctgggcata tggatgtcgt
    61021 ggcggctggt gatgaatcgt cttggaccta tgcacccttt gcagcagaaa tccatgggaa
    61081 ccgtttgtac ggacgtggtg ctacagatat gaagagtggc ttggcagcaa tggtgattgc
    61141 catgatcgaa ctgaaagagt caggaaaacc atttaacgga acagtcaaat tattagccac
    61201 tgtcggagaa gaagtgggtg aactaggtgg ggaacagctc acgaaagcag gctatgtaga
    61261 tgacttagat gccttgatca tcggagagcc aaccaattac agtttgatgt atacgcacat
    61321 gggatcaatc aactatacag tcacctcgca cggaaaagaa gcgcatagct ctatgccaga
    61381 ccaaggttat aatgcaatca atcacctaaa tgaattcatt acgaaagcaa atgctgaaat
    61441 gaatcacctc gctgaaacaa tcgagaatcc tgtcctagga aaaacaatcc ataatgttac
    61501 attgatcagt ggcgggaatc aagtcaacag catcccaagc catgcgcagc tccaagggaa
    61561 cattcgatcg attccagaat acccaaatga taaaatcatt gcattgctgc aatcaatcgt
    61621 caatgaattg aatcaagaga cagactatca tttggaattg atgatcgatt acaacaaaat
    61681 acctgtcaaa gctgatccag attctccttt gattcattgc attcagcaac aattcagcca
    61741 gccattacct ttagttggag cggcagcaac aacggatgca gccgaattta cgaaagctaa
    61801 ccattccttc gactttgtcg tctttgggcc tggtgtcgtt actttgcctc atcaagtaga
    61861 tgagtatgtt gaaatcgata attatttgga tatgatcgaa aaatatcaag gaattatttt
    61921 atcctactta gcgtaagatt tttttaataa atgaaaaaac agagccagat tagcattatt
//
LOCUS       DADQDV010000008        61793 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.008, whole genome shotgun sequence.
ACCESSION   DADQDV010000008 DADQDV010000000
VERSION     DADQDV010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 61793)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61793)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61793
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.008"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(233..1081)
                     /locus_tag="J8S10_000531"
     CDS             complement(233..1081)
                     /locus_tag="J8S10_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAZ9629142.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(1305..3245)
                     /gene="thrS"
                     /locus_tag="J8S10_000532"
     CDS             complement(1305..3245)
                     /gene="thrS"
                     /locus_tag="J8S10_000532"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HAZ9629143.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(3582..3761)
                     /locus_tag="J8S10_000533"
     CDS             complement(3582..3761)
                     /locus_tag="J8S10_000533"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HAZ9629144.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(3808..5631)
                     /gene="cadA"
                     /locus_tag="J8S10_000534"
     CDS             complement(3808..5631)
                     /gene="cadA"
                     /locus_tag="J8S10_000534"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HAZ9629145.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            5909..8188
                     /locus_tag="J8S10_000535"
     CDS             5909..8188
                     /locus_tag="J8S10_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAZ9629146.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(8281..8928)
                     /locus_tag="J8S10_000536"
     CDS             complement(8281..8928)
                     /locus_tag="J8S10_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629147.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(9107..9826)
                     /locus_tag="J8S10_000537"
     CDS             complement(9107..9826)
                     /locus_tag="J8S10_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAZ9629148.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(9957..11108)
                     /locus_tag="J8S10_000538"
     CDS             complement(9957..11108)
                     /locus_tag="J8S10_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HAZ9629149.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(11325..12065)
                     /locus_tag="J8S10_000539"
     CDS             complement(11325..12065)
                     /locus_tag="J8S10_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAZ9629150.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(12069..12392)
                     /gene="rsfS"
                     /locus_tag="J8S10_000540"
     CDS             complement(12069..12392)
                     /gene="rsfS"
                     /locus_tag="J8S10_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HAZ9629151.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(12449..13042)
                     /locus_tag="J8S10_000541"
     CDS             complement(12449..13042)
                     /locus_tag="J8S10_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAZ9629152.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(13026..13673)
                     /locus_tag="J8S10_000542"
     CDS             complement(13026..13673)
                     /locus_tag="J8S10_000542"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HAZ9629153.1"
                     /translation="MNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHLV
                     MAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIELA
                     RGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPGY
                     TTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(13686..13997)
                     /gene="yhbY"
                     /locus_tag="J8S10_000543"
     CDS             complement(13686..13997)
                     /gene="yhbY"
                     /locus_tag="J8S10_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HAZ9629154.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(14013..15122)
                     /gene="yqeH"
                     /locus_tag="J8S10_000544"
     CDS             complement(14013..15122)
                     /gene="yqeH"
                     /locus_tag="J8S10_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HAZ9629155.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(15119..15646)
                     /locus_tag="J8S10_000545"
     CDS             complement(15119..15646)
                     /locus_tag="J8S10_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HAZ9629156.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(15826..16611)
                     /locus_tag="J8S10_000546"
     CDS             complement(15826..16611)
                     /locus_tag="J8S10_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HAZ9629157.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(16604..17473)
                     /locus_tag="J8S10_000547"
     CDS             complement(16604..17473)
                     /locus_tag="J8S10_000547"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HAZ9629158.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(17474..18853)
                     /locus_tag="J8S10_000548"
     CDS             complement(17474..18853)
                     /locus_tag="J8S10_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HAZ9629159.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(18861..19280)
                     /gene="fabZ"
                     /locus_tag="J8S10_000549"
     CDS             complement(18861..19280)
                     /gene="fabZ"
                     /locus_tag="J8S10_000549"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HAZ9629160.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(19305..19781)
                     /gene="accB"
                     /locus_tag="J8S10_000550"
     CDS             complement(19305..19781)
                     /gene="accB"
                     /locus_tag="J8S10_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HAZ9629161.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(19784..21019)
                     /gene="fabF"
                     /locus_tag="J8S10_000551"
     CDS             complement(19784..21019)
                     /gene="fabF"
                     /locus_tag="J8S10_000551"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HAZ9629162.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(21038..21775)
                     /gene="fabG"
                     /locus_tag="J8S10_000552"
     CDS             complement(21038..21775)
                     /gene="fabG"
                     /locus_tag="J8S10_000552"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HAZ9629163.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(21787..22704)
                     /gene="fabD"
                     /locus_tag="J8S10_000553"
     CDS             complement(21787..22704)
                     /gene="fabD"
                     /locus_tag="J8S10_000553"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HAZ9629164.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(22811..23035)
                     /locus_tag="J8S10_000554"
     CDS             complement(22811..23035)
                     /locus_tag="J8S10_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HAZ9629165.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(23088..24050)
                     /locus_tag="J8S10_000555"
     CDS             complement(23088..24050)
                     /locus_tag="J8S10_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HAZ9629166.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(24060..24500)
                     /locus_tag="J8S10_000556"
     CDS             complement(24060..24500)
                     /locus_tag="J8S10_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAZ9629167.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            24806..25771
                     /locus_tag="J8S10_000557"
     CDS             24806..25771
                     /locus_tag="J8S10_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HAZ9629168.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(25828..26058)
                     /locus_tag="J8S10_000558"
     CDS             complement(25828..26058)
                     /locus_tag="J8S10_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HAZ9629169.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(26144..27031)
                     /locus_tag="J8S10_000559"
     CDS             complement(26144..27031)
                     /locus_tag="J8S10_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HAZ9629170.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(27120..28343)
                     /locus_tag="J8S10_000560"
     CDS             complement(27120..28343)
                     /locus_tag="J8S10_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAZ9629171.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(28360..29439)
                     /locus_tag="J8S10_000561"
     CDS             complement(28360..29439)
                     /locus_tag="J8S10_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAZ9629172.1"
                     /translation="MLYYISEGGRKVKVLLYFESEKMLAKSGIGRALDHQKRALTEVG
                     ISYTLDEKEDYDILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIRSNQL
                     SPIVKKYLVGLYQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQ
                     KFREYFKLSPDQKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIR
                     KIVKEDHPENVLFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVR
                     DIPVYNGWLEDSKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEE
                     LKNVYESVLNEKVSSKLKKVNQVKD"
     gene            complement(29570..31297)
                     /gene="ptsP"
                     /locus_tag="J8S10_000562"
     CDS             complement(29570..31297)
                     /gene="ptsP"
                     /locus_tag="J8S10_000562"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HAZ9629173.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDMMEEV
                     VELVHEYVK"
     gene            complement(31297..31563)
                     /locus_tag="J8S10_000563"
     CDS             complement(31297..31563)
                     /locus_tag="J8S10_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HAZ9629174.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            32042..34276
                     /locus_tag="J8S10_000564"
     CDS             32042..34276
                     /locus_tag="J8S10_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA domain-containing protein"
                     /protein_id="HAZ9629175.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            34424..34744
                     /locus_tag="J8S10_000565"
     CDS             34424..34744
                     /locus_tag="J8S10_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HAZ9629176.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(34949..35173)
                     /locus_tag="J8S10_000566"
     CDS             complement(34949..35173)
                     /locus_tag="J8S10_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HAZ9629177.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(35371..36951)
                     /locus_tag="J8S10_000567"
     CDS             complement(35371..36951)
                     /locus_tag="J8S10_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HAZ9629178.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(37352..38728)
                     /locus_tag="J8S10_000568"
     CDS             complement(37352..38728)
                     /locus_tag="J8S10_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HAZ9629179.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(38856..39974)
                     /locus_tag="J8S10_000569"
     CDS             complement(38856..39974)
                     /locus_tag="J8S10_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAZ9629180.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            40116..40550
                     /locus_tag="J8S10_000570"
     CDS             40116..40550
                     /locus_tag="J8S10_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAZ9629181.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(40628..41161)
                     /locus_tag="J8S10_000571"
     CDS             complement(40628..41161)
                     /locus_tag="J8S10_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HAZ9629182.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(41255..42433)
                     /gene="mutY"
                     /locus_tag="J8S10_000572"
     CDS             complement(41255..42433)
                     /gene="mutY"
                     /locus_tag="J8S10_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HAZ9629183.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(42426..43223)
                     /gene="recX"
                     /locus_tag="J8S10_000573"
     CDS             complement(42426..43223)
                     /gene="recX"
                     /locus_tag="J8S10_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HAZ9629184.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            43330..44712
                     /gene="rlmD"
                     /locus_tag="J8S10_000574"
     CDS             43330..44712
                     /gene="rlmD"
                     /locus_tag="J8S10_000574"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HAZ9629185.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(44886..45464)
                     /locus_tag="J8S10_000575"
     CDS             complement(44886..45464)
                     /locus_tag="J8S10_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitin-binding protein"
                     /protein_id="HAZ9629186.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            45786..46256
                     /locus_tag="J8S10_000576"
     CDS             45786..46256
                     /locus_tag="J8S10_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HAZ9629187.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(46364..47590)
                     /locus_tag="J8S10_000577"
     CDS             complement(46364..47590)
                     /locus_tag="J8S10_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytR family transcriptional regulator"
                     /protein_id="HAZ9629188.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(48344..48544)
                     /locus_tag="J8S10_000578"
     CDS             complement(48344..48544)
                     /locus_tag="J8S10_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAZ9629189.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            complement(48678..49286)
                     /locus_tag="J8S10_000579"
     CDS             complement(48678..49286)
                     /locus_tag="J8S10_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HAZ9629190.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            complement(49371..49841)
                     /locus_tag="J8S10_000580"
     CDS             complement(49371..49841)
                     /locus_tag="J8S10_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HAZ9629191.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            complement(49889..50803)
                     /locus_tag="J8S10_000581"
     CDS             complement(49889..50803)
                     /locus_tag="J8S10_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HAZ9629192.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            50949..51752
                     /locus_tag="J8S10_000582"
     CDS             50949..51752
                     /locus_tag="J8S10_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HAZ9629193.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            51930..52877
                     /locus_tag="J8S10_000583"
     CDS             51930..52877
                     /locus_tag="J8S10_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HAZ9629194.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(52945..53238)
                     /locus_tag="J8S10_000584"
     CDS             complement(52945..53238)
                     /locus_tag="J8S10_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HAZ9629195.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEIDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(53266..53931)
                     /locus_tag="J8S10_000585"
     CDS             complement(53266..53931)
                     /locus_tag="J8S10_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HAZ9629196.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(54071..54703)
                     /locus_tag="J8S10_000586"
     CDS             complement(54071..54703)
                     /locus_tag="J8S10_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAZ9629197.1"
                     /translation="MIKVLLVDDHEMVRLGVSFYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(54710..55777)
                     /locus_tag="J8S10_000587"
     CDS             complement(54710..55777)
                     /locus_tag="J8S10_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAZ9629198.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            complement(55774..56505)
                     /locus_tag="J8S10_000588"
     CDS             complement(55774..56505)
                     /locus_tag="J8S10_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HAZ9629199.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            complement(56674..57153)
                     /gene="greA"
                     /locus_tag="J8S10_000589"
     CDS             complement(56674..57153)
                     /gene="greA"
                     /locus_tag="J8S10_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HAZ9629200.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(57289..58464)
                     /gene="mltG"
                     /locus_tag="J8S10_000590"
     CDS             complement(57289..58464)
                     /gene="mltG"
                     /locus_tag="J8S10_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HAZ9629201.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
     gene            58668..59837
                     /locus_tag="J8S10_000591"
     CDS             58668..59837
                     /locus_tag="J8S10_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HAZ9629202.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVAHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
     gene            complement(60104..61726)
                     /locus_tag="J8S10_000592"
     CDS             complement(60104..61726)
                     /locus_tag="J8S10_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629203.1"
                     /translation="MNLKKIFSVKIFIVYAFVSLLYLFPAFKNMEIFGFYDTAFHINR
                     ALSLESIFSSPINFETFRSYGMQVNNFYPWLTLYPLFLLIKFTNLAIGYNLFLYIVTL
                     ITLFICHYVMYEITKKHVTSSFFAIIYTTSSFRSVEIFLRGAMGELLAMSILPLILLG
                     FIKLYDSKKESWVMLAISMTLLIYTHVLSVAMTMVMIIIALIIQFYRKKKIEIFLIIK
                     LIKAAIVTLLLSLAFIGPMIEQTLYQDLNRPYVDILQKRAIYLGKEFLIGSIDSELLS
                     FGIGLTLLICLIILTFNFKKLGILSKITYIMGIISILLCTKIFPWFALQNTPLNIIQA
                     PWRFMIFSTLFISFSVSLFISPQLEKFSYTRRRNFILLLILAISILNYSSVVNMVKEM
                     NFQGTYSNEQMENKLEEFENFDYVPIGYKKDQLLLKNHQVTEDGQVIYSSFSPNKDEI
                     TFTFKSSKGKTIVLPVFRYKGLTVTVNSKNATVLKQGGPFVTVKSESGINKVTIRYSY
                     TFFSKISLFISIITLIVLLFYCIKLKIRTSHE"
BASE COUNT        18106 a        12838 c        10353 g        20496 t
ORIGIN      
        1 aagaaaaaat gggcggagca agaaattctt tacctaattt caagataaaa tcaacttttt
       61 gtttcacagc aatcacttaa agttacatat ccaactattt ttttcattaa aaaataaact
      121 tatttttgaa aattatgttt tcttaagtcg tgaaacactt tgatggatca tttatttgtg
      181 gaaaactacg ttttgttatt ctaaaaaact tatataaaaa atagtaaggt ttttatttcg
      241 aatccataaa atattcttgg attgcttctc gtgttttttt cactttttcg ctaagctttt
      301 cgtttttagc catatagaaa taaaaaatga tatcgatcgt agcaaattgg gccaaaagtg
      361 aattagttgc cgcacttcga ttcgtgattt cttttggtct agatgtttgt acgagtacat
      421 cggctatctt gctaagcggg ttatttccaa attgcgtcaa cgcaatgatt tcgatattca
      481 tgcttttcgc cagctcggct aatgcgacta catctgcact tctacctgag tttgaaacaa
      541 gccaaagcac tttctttttc tcattgctga caagttgcgg gagcaagacg tggatatctt
      601 tttcaaaaat gattggctta ccgacacgag accatttttg cagaatatct tctactacta
      661 aagaagaggc gccaacccca tataaaaaaa cagtctctgc cgattccaaa cactctacga
      721 ctttttggat cgtttcttct tctagaatat ctactgtttc ttttatcgct acttgtgcat
      781 tgttaccaag tttgtttttg atagagtaaa aggactcatt tgcttctata tcactaaaac
      841 cttcatcgat tccagtctgt agttctgttg aaatcgtgat tttgaagtcc gtcagacttt
      901 gaaaaccgat ttttttggaa aaacgtacaa ctgtcggcgc actcaacccg gaagcttctg
      961 ctaattcatt agctgtcatt gtagggacct tctcaatatt accgataatg tagttggcca
     1021 actttttttc tgctgaagaa taatcttcca tcatactttc aatacgacta attacgctca
     1081 taagttcctc caccctttta atgatagtct atgtaagtat accatatcag acccttattc
     1141 acggtcgtat actggataaa aaacaaaaaa acaatccgcc caacagaata tcttatccca
     1201 tcaatcccac agattctatt gagcatctgt gtctttgagg aatacctgtt atctattgtt
     1261 cggattgctt tctatctact acttttttac aggaaattta cctattagtt ttctctgctg
     1321 taatttttga cttctgcttc catagcatca ataaagatat tcaaatcttc tacagctgtt
     1381 tctttacttc cataacgacg tacgttcact gttgcatctt ccaattcctt gtctccaaca
     1441 actaattggt aagggatctt ttgtgtttga gaggcacgta tcttatagcc cattttttca
     1501 ttacgatcat caacttctac acgcaacccc ttcatttgca aacgttcttt gatttcataa
     1561 gcataatcgc catgtgcatc aacagaaaca gggatgattg ttgcttgtat aggtgccaac
     1621 catgttggaa aagcgccttt gtatacttct gttaaataag cgacaaaacg ttccattgta
     1681 gaaacaattc cgcggtggat aactactgga cgatgcgtat tttccccgtc ttctccaaca
     1741 tatgtcaaat caaagcgctc tggcaataag aagtctaatt gtatagttga taatgtttct
     1801 tctgtaccaa gagctgtttt gacttgaaca tctagttttg gtccgtaaaa ggctgcctcg
     1861 ccttctgctt caaagtaatc tagttctaat tcatccatag cggctttcag cattgcttgg
     1921 gctttttccc acattgcgtc atcatcaaaa tatttatctg tattgtttgg atcgcgatag
     1981 ctcaagcgga aacgataatc tgtaatattg aagtcagcat atactgccac catcaattca
     2041 agcgtacgtt taaattcatc tttgatttga tcaggacgaa caaatgtatg accatcattc
     2101 aacgtcattt ctcgtacacg ttgtaaacct gacaaagcac ctgatttttc atagcgatgc
     2161 atcattccta attcagcgat acgaattggt aattcacgat aagaatggat cgtgtttttg
     2221 tagaccatca tgtgatgagg gcagttcatt gggcgaagaa caagcatttc gccatctccc
     2281 atatccattg gcgggaacat gtcttcttga taatgatccc agtgtccaga tgttttgtac
     2341 aactcaacat ctcccattat tggtgtatat acatgttggt aacctagact aacttctttg
     2401 tctacgatat aacgttcgat cgtgcgtcgg attgttgccc cttttggaag ccagaatggc
     2461 aaaccagaac ctacttctgg ggaaaccatg aacaagtcaa gttcttttcc tagtttacga
     2521 tggtctcttt cttttgcttc ttcacggaga cggatatatt ctttcaaagc tttcttgtca
     2581 aaaaaggctg tcccgtatac acgttgcatc atttgattgt ttgagtttcc acgccaataa
     2641 gcacctgcca ctgataataa tttaaatact tgtatacggc cagtggatgg aacatgtggt
     2701 ccacgacaca aatcgatgaa ttcgccttgt tgataagcag taatcacttc ttcttctggc
     2761 aattcactaa tcagttctac tttgtacgga tcacttgcaa aaatttctaa tgcttcctgt
     2821 tttgaaagaa cacggcgttc gatcggcaga ttttctttga cgattttcat catttctgct
     2881 tcgattgccg gcaaatcttc tgcagttact tggttttgtc cattatctgt atcgtagtaa
     2941 aaccctgaat cgatagctgg tccaacgcca aagtggatat ttggatagag gcgacgcatg
     3001 gcttgggcca tcaaatgagc tgctgaatga cggactaagc caagtgcatc ttcatggtct
     3061 ggtgtgatga tctcaatact tgcatcttcc tcgattggac gagtcaaatc aacgagtttt
     3121 ccgttcactt taccagctaa agcttttttt gctaagcttt ttgaaatgct ttcagcaatt
     3181 gccaatgttg ttgttccaga ctcaaattct ttgactgcac catctggaaa agtaattttt
     3241 atcataatag tttcctcctt gaaatgtttt gattgatcag atcatcaagc tgaaaaacaa
     3301 aaaaatccta gcatctcttg aaaagagata ctaggacgaa aagttcgtgg ttccacctaa
     3361 tgttcaaacg caaatgcgtt cctcaagcgt tgtaacggtc cgaccgccct tgcttcaaca
     3421 agggtttcga aagtggtcat cctttggttt tctcctggaa aagtttcagc ctagcttttc
     3481 ctctcttatc gaagactctc aaattcagtt ggctttctca tcaatcaatt atgtgtttat
     3541 ttaaccacta ataaatagaa aaatcaagtg ggaaactaaa cttatttttt ccattcccca
     3601 tttacaccgt atgttccttt tttcatctca ttgatgatga catggatgtg ttcttttggt
     3661 gcctgcgtgt ttttatgaac agcttccgtg atatctttca tcatattttc taattgttcc
     3721 ggactgcgac cttctactaa ttcgacatgt acgaatggca taatgctctc tcctctttct
     3781 gatcgttctt ttttcaactc gattctatca tactatgttt gtcttgggta ctgaatcagg
     3841 aaaaatggct ggatcttttt ttgctctcaa ggcactcaaa atagagaccg tatccacgac
     3901 ttcttgcaaa acagctccga ataatgcggg gattagtccc gtacttgcaa ttaacatcaa
     3961 aaaaatacaa ataaagatgc caatcagtac agactgtttc gctattctca tcgtatctct
     4021 tgaaatcact actgcttttg ctacacgcaa gagatcatct ttcaagatga ccgcatctgc
     4081 actttcacta gcagctgtag aaccatgagc ccccattgca ataccgatat ctgcagcagc
     4141 aagtgctggt gcgtcattca cgccgtctcc taccatcgca acaggtcttt gatctttagg
     4201 gatactttct aaaatggtca gtttatcttg aggcaagcta cgggcatgta cagaatctaa
     4261 ttggactttt tctgcaatcg tttgagcaat ggcagatcca tccccggtga tcatcatcaa
     4321 atttttcaca tcaagttttc ttagctcctt gattgtcttt gctgcttctg ggcgaatctg
     4381 atccgaaaat aggatcgttc ctgcaaaaga tcgatcaatt gttacataga ttgctgtatt
     4441 ggacgtttct atttcttcag ctgaaacaaa agaggcacgt ccaatcttta cttcatgatt
     4501 attgactact gcttggattc cttgaccggt cacttctttc agttgactaa caggatacag
     4561 ttggctgttt ttcacgttgt tcactaacga acgagctaag atatggctag attcctgttc
     4621 tgcactagct gcatacagaa gtagctcttc tttttttatt ccattgactg gctgaatcgc
     4681 ctctacttcc aatatccctt tggtaagcgt tcctgtttta tcaaaagcaa tcgtttttgt
     4741 acgtgcgagc ttttcaatcg ttgttccagt ttttacaacg atcccgtttt tacttgaacg
     4801 gctcattcct gcaactaaag caatgggcgc agctagaatc agtggacaag gtgatgccac
     4861 taccagtacc tcagcaaatc gtaaagggtc ttttgagaac caccaagaaa taccaccgat
     4921 caaataagca atcaacgtga aagggactgc ataacgatca gctaaacgga caaatcgggc
     4981 aggcttttct tttgattctt cgactagttt aataatcatt tgatactggc tgtctgcggc
     5041 acgtttttca gcgatcattt ggatcgatcc gtctccattt aaagaccctg acataatctg
     5101 atctccaggt ttcttggttt ccgggcggga ctcacctgtc aaagaagatt catcgaccga
     5161 agattctcct ttggtcactc gaccatctgc gggtacaagt tcgccaggct tgactagtaa
     5221 ctggtcatca atatttattt catcgattac tatatcctgc aattttcctt ctttgaatcg
     5281 atgggcaatt cttggggtgt tatctaacaa agactgcagt tctttacccg ctcgtttatt
     5341 cgcgtaatcc tctagactat ctccgcccgt aagcatgatc aatatcatca aactagccca
     5401 gtattctttg acggctaatg ttgcaaggat tgcggtaatc gctaatacat ctacgccata
     5461 tcttcctgaa cgtaacgtct tgatcatttc caaaaacatc aagaaggcga gaatccctcc
     5521 agtaaatgcg acaatcgcaa atgcaagggc cggctggtga aaaacaaatt cacttaataa
     5581 agctatccca ccaataagca aagtaagtaa aaattttttg aaatgtgtca ttgttttttc
     5641 tcctctttta tgtgacttag agaggttagt aataaatttc cagctgcctc tttcatctta
     5701 agcatagtcc ttgactagca ctttttaaaa caataggcct taattgaaaa caactatcac
     5761 tatcagcgtt tccaaaattc atcagttcta caaacaaaaa tattcagcaa ggattacttt
     5821 ttcgattcat cagttaaaaa gtaccttttt tcgaaaaact atgctatact tttaattcgt
     5881 tatttacggc ggaaggagca aacatgcgat gaatgagaaa caactagaac aaacgcacgt
     5941 ggatgaaacg atcgaactaa tccagatcga acaaaatatg ctggatacaa aacaacaaga
     6001 attgactcag gaaatgaatc attcgacaaa agacacagct aatcacaaga ttcgagctgg
     6061 ttccaatgaa gctttttatg aatctgctgt tgaatatcgc caacatgagc aggaattgct
     6121 tttgaaatac catactcttg aagcacagca aaaacgcctg caaacgttgt ctgtcatgaa
     6181 agatagtcct tattttgccc gtatcgactt taaagaagac cgtgaaacag aaacattata
     6241 tctaggtatc gcttctttaa gagatctggc agaagaaaca atcgttattg actggcgcgc
     6301 accaattgcc aatctttatt atgaaggtga gattggtccc gcattttatg aaactgaaac
     6361 agatagaata gatgtcgatc tgcagttgaa acgacaattt aaaatccaag aaggacgtat
     6421 tttatctatg gtagatacgt cggaagtaat caatgatgac tttttgctag agatattgga
     6481 tgaatcatca agcaaccata tgaaaaacat cgtctctacg atacaaaaag cacaaaatgc
     6541 aatcattcgg gacacaacaa gtaaagtaat gctgattgaa ggaatcgccg gaagtggaaa
     6601 gacatccgct ttgcttcaac gtattgcttt tctgttgtat cataatcgca agtggctcga
     6661 ggctgaaaac gttcttctat tttcacccaa ccatttgttt tctgattaca tctcgactgt
     6721 attgccttca ttaggtgaaa gcggcgtgcc tacacagaca ttcaaaaatt atttggtgca
     6781 gctgctgcca gagttttctt tactagatga acagcaacaa gaaagtggtt ttttgctagg
     6841 ggaaaaagat ccgatacaag tgatgaaaag cggattgacc ttagtcgatc agattgatcg
     6901 ctatatccaa ggcatcacaa actacggtcc cttgttccgt gatatgaaaa taaatggccg
     6961 tacgatccta tcaaaggaat cgattcgcca atggtataaa gaaacaaatg aacaattacc
     7021 tttacatcat agactttctc tattacaaac gaagctcctg aaaaaattag gcggtctgca
     7081 aaaagacgaa acacgtcagc aatgggtcaa agatctggcg gaagaacagc tccaagaact
     7141 atacgcaaca gatccaaatc ttgaatatac agaacaaaag gagcgttcat tacgtaaaaa
     7201 actggccaac caaatcgtac gtaaaagatt ccgtcgaatc catcgaggga tcatgaatta
     7261 tcaatttgtc aatataacga aacaatatct ccactttcta caaactgtgc cactttctct
     7321 tctaacacga cataaaatca gcgagaccag gtggcaggaa catttgacaa ctgttcgtac
     7381 acacttgcgt caaagagaat tgcgtcaaga ggatgctgta ctattctttt tactgatgcg
     7441 ccgaacatat ccagtgacgg ttacacacaa agctcgctat atctttattg atgaaatgca
     7501 ggatttcgca ccatcacaag tggcattgct gcaagccttg ttcccaaaag caaatttgac
     7561 tttctgtgga gatctaaatc aaaatgtctt tggaaatgaa acgatcgttg gatcattgga
     7621 agaccttttc gtggaccgtg aagtcactcg tttccaatta acgacaagct atcgctccac
     7681 aaaagaaatc actgattttg ctaatcattt tattgtgaaa gaacatcaag tagaaacaac
     7741 agcaagaaaa ggagaccttc ctttgctcat ccaaggaaca acagatgata tcaaattgaa
     7801 ttggttagca gataccattc gaacgactca gggaaaagcc cggtattggc gtacagcaat
     7861 catagctaaa acacaagaag aatgcgaagc tctttatgct caactgccag acgagttgaa
     7921 acaacaagtc cagctgattt taaatgagag tgactttatg aagcgttcca ttattttact
     7981 tccagccttt ttagcaaaag gtctggagtt tgaccgagtt ttcttgtggg atgtagatgc
     8041 agaacatttt tcttctcagc aagacaaatt gatcctttac accatgtgta cacgtgcgat
     8101 gcatgaattg acccttttta cctccaataa tgaaagtcct ttgttaaaca atatggatat
     8161 ttcatcttat gagaaaaaag tactgtaagt aaaaagacaa ctgctatcat taatgttagc
     8221 agttgtcttt ttatttacaa taataattgc agaaaaagta attcaatcat ttaaggtcat
     8281 ttattctata tataaatcca aatctgtttc aggatatttt aatttgacaa gcgaaataat
     8341 cattttcagt tcttccatgt tttctggata ttctgggtca aataccttgc tatgacggcc
     8401 aatcccgcca ttgtcgatca atcggtaaat tcgattccat tcaatgaatt ggtcaattga
     8461 ttggaaattg ctgattggat agccgccaca atccaaaatc tctgatacac gaaatgctag
     8521 gtatgcacta tcgatcactt tatttttttt cgtgtctatc ttctcatttc tttcgataag
     8581 aattttttca ggacgatgtt tcaagctcca ctctaatagt agaaagaaag cctccatccg
     8641 atactcttct tcaaataacc gaaaggctga atcagaacga cgaaaaagca gcggaatcag
     8701 ataattttgt ctataaatca gcattggtgc gcggtccacc atacactcta aataacggtt
     8761 cagataccct gtaccgacat agtttcctaa tcgatagcct tcaacgccga atcttgcgta
     8821 tttttgcgct aattttgaac aatcagttac gttcacagct aactcttcta ctttgcggta
     8881 accgcttaag atacgttcaa aaggttctaa agtgattttt gcttccatat tcttccccgt
     8941 ccatcttcca catacttcat atcatttcac atgatactta tgctctcatc ataccacagg
     9001 ttgaattaga aaagaaaata aatcacacaa aaaagcaaga caatctgtta gtgagattgt
     9061 cttgcttttc gaaaaagact gaatactttt cgttaaaact ggttgcttag tcttctaatg
     9121 ccacattatg gaacacatgc tgtacatctt ctagatcttc cagtgcatca atcatttttt
     9181 caaatgtttc ttgatcttct ggagatagtg ttacctcgtt ttgagggatc atttggatct
     9241 cagcgattga aaaatcagtg attccttttt cttttaatgc ttcttgtata ctatggaaat
     9301 ccgctacttc accgtaaacg atgatttgtc cttcttcttc cattacatcg cgaacatcga
     9361 tgtctttttc cattaggtat tcaaggatct cgtcagcgtc ttctcctgca aaagcaaaga
     9421 ttgctgtatt gtcaaacatg taagaaaccg ctccggaaac acccatgttc ccgccatttt
     9481 tcccaaatgc tgcccgtacg tctgctgctg ttcgattcac attgttcgtc aatgtatcaa
     9541 caatcaccat tgagccgctt ggtccaaatc cttcatagcg caattcagag tatgtttcat
     9601 ctcctgcacc ttttgctttt tcgattgctc ggtcaataat atgttttggt acattataag
     9661 ttttagcgcg atcaatgacg aaacgtagtt tttggtttgc atgcggatca ggatcacctg
     9721 attttgctgc cgcgtagatt tcaatcccaa attttgcata aatccggcta ttattagcat
     9781 ctttagcagt tttctttgct acgatatttg cccatttacg tcccatattt tcacttcgct
     9841 ttctgatttg atagtttcat aacgcaaaaa cgtcctgttc cattatactt gtgaatcacg
     9901 attctgtgaa gctttttttc tttcttcctt cattcttctc atttttagtc aattatctat
     9961 actcggattg ggatttgccc gaaattctgt tccggaatat tgcctcccaa ttgatagatt
    10021 tgatcacttc taactaacag ttccgcttct tgtgcctctt tttttccgat tcgggaataa
    10081 atagaaatct cttttttttc ttttaagaat cttcttccag catcggtaaa tccaagtagt
    10141 cgaagataat ttttattttg ttggacagga atctcttgct ttttgatatt cagcaagaca
    10201 taacaagata atcgttggat ccgtgtccat gtatatcttt ttgtttttac ctttgacaca
    10261 aaatcctcaa aactatcagc agttgcagct gctgttttca tgcgcgattc tattccttcg
    10321 gtcatctgat agatatctgt cagttccagc aaagtagaag ataacaaccg ataacgcaaa
    10381 tacggccaat aagattccca agtctgcagc gaacaagttg aaagatcttc ttctgtctga
    10441 ggcggcacaa gtccagctat tctttttcct tcttctaacg catggcgaat ggctgttgca
    10501 ctggctatcc tctgatctgt gatgattttt tcatgatagc ctgcactttt acgtcggatc
    10561 ggatgtaatt ccatagggtg gacatacttg gcattttcct ttgcataact taatcccaag
    10621 atatgatttg gcgaagaaaa atcaagcgta atatcgggat acagactgcg aaaaacctca
    10681 gtcatttttt gcggataact atacgtttga tcagacagtt cttgaaatgc ctcttctatc
    10741 ctatcttgat tctcttggac aaagcgtccg aaactgctgt aatcaaacga agtctcttct
    10801 tctgttccaa aacacaaact gtcacagtcc agtgtttgca agatttttac tgcaccttta
    10861 gcaaaatagt cagctgactg aaccgcccat tcgacgggaa gctccactac taaatccaca
    10921 ccattttgta aagcttcatt cgcgcgatgc catttatcga tgatagccgg ttcgcctctt
    10981 tgcaaaaaat tcccgctcat tacagcaatg acgacctctg ctcctgttat ttttcgtgcc
    11041 atttccacat gatagcgatg tccattgtga aaaggattgt actctacgat aatcccgcag
    11101 cttttcatgc gcatcctcct tcatagttat cgataaaaaa gaaatagaga caagtaaaaa
    11161 aaggcaaaaa tcggaaaaaa tacccgaact atataaacta ttctcgcaaa cacaatactt
    11221 ctgcgacgaa aagctgcact gcaagagcaa tgcctatatc gttcggatat ataatttatg
    11281 ttgaagattt attcttttct tgttaactcg agcaggcaaa accgctagtc tttgtatgct
    11341 acaaagaacc agcgctttga tttctctgat gctgcttcgt ctgtaaaatc agaaaatgct
    11401 tcgactttcg aaaagccgct gttttccagc attcttaaat aactttccaa tggataggta
    11461 cgctcttgat gtagttcatc ttcacgaata aatcgaccag acccttcttg ttcttcaacg
    11521 aaaaaggtaa gaaaatgttc gatgctgtgt ttctcgcttc ctggataact atcccacaaa
    11581 aaagcaaaat tatccccttg ataatgatag ctatattctg gaaaaacctc atctacttga
    11641 taggtggagt gtacgtcaaa taaaaatcgg ccattttctt ctaacgcttg atagacttca
    11701 tcaaacactt gctgtacctc ttgtctattt ttcatatagc acagcgaatc agaaaaacag
    11761 gtaattgcct gatattgtcc gatttctgat aaatcgagca tattgccttc cacaaattgg
    11821 atcgatgcgt cttcttcata tgctcgctgg ctggcaatca tcaacatctc ttctgaaagg
    11881 tctaaccctg tcactttata tccatctttt gcaaaggcaa ccgctaatgc tccagtaccg
    11941 catgccagtt ccaaaatatt ttttgtgtct tcttgtaaat gacgtttcga aaaagctaac
    12001 cattgctgat aaagtgtttc gtccatcact tcatcgtaaa tgaaagcaaa tgtttcataa
    12061 gccatatgtt aatccaacca ttcactaaga tcgactagcg gagcatctga ccatagtttt
    12121 tccagattat agaaatttcg ttctggcgca tggaaaacat gtacgatcac atctccaaga
    12181 tcgatcaata cccattttcc gccttctttt ccttcaatac gttttacttc atatttgttt
    12241 tcttcttctt tatcaatgat ttcttctgta attgcgttga tttgacgttc gctatttgct
    12301 gaacagatca tgaaataatc tgccaacaag gaaacatttc gaacgtctaa agcgataatg
    12361 tcttctgccc gttttgaatc tgctgcttca atcgcaattt ttaattgttc tttactatct
    12421 atgatgattt cctcctaata tgagcagctt atttttttgc tacccagtaa ttatatgttt
    12481 cgattgtttt tggataaatc tgttgttctt gcgcaagcaa atgggccaat gtatgttttg
    12541 tttcaaatgc tacagcttcg tctagatcag cccatgcaat ggctcgtgca tcttgtaccc
    12601 caggaaaatc tcgacctggt tcaatatagt ctgctacata aatgattttg tcaaggagac
    12661 tcatcttagc agccccagtc gtatgcaccc ggattgcatg aagaatctct gcatcggtga
    12721 ttcctaattc ccgctctaca aacgaagcgc caacaagacc atgccagatt gcattattat
    12781 aattcaataa ctccggatca aaaccgtctc ttacgattac cattttgaac tcctcatctg
    12841 gtcgttcttt tgcataatca tgtgtcaatg cagcaatact agctttttca ggagaagcac
    12901 cgtatttttt ggcaagagcc acggctgttt cttctactcc aagcacatgc ttgaagcgtt
    12961 gttcgctcat tctcatctgt attttttgca tcaggttttc tctagaataa gcagtatatt
    13021 cattactata gtccatattc atacaaccct tcattttgaa tataatcaat tactttatct
    13081 ggaacaaggt agcggataga acagccttct ttgatctttt gacgtatttt cgtggaactg
    13141 atgtcgatct caggtacatc tacccaaatt acaggatatg gagtatccgt tgtgtatcct
    13201 ggtcgacgta tacccacaaa gttgaccata gaagtcagct catcgatttt ataccatttt
    13261 ggcaaatatt ctaccatatc cccaccgata ataaagtaat aatctgtatc cggattgttt
    13321 tgcgtcaatt ccttcatagt atcataggtg taacttttcc caccacgagc taattcaatc
    13381 gtttcaatct gcaaaaaagg attgtcttcc accgctaatt ccaacatgtt gagtcgatgt
    13441 tttgcatcaa tcgtctgttt ctcatcaaca tgaggtggct gataagaagg catcaaaaat
    13501 acgcggtcaa gacctaaatt ccggccagct tgttcagcca tcactaaatg tgcaaggtga
    13561 acgggattga atgttccgcc caagatccct acttgctttt tcttctctaa gaattgaggc
    13621 atttcttcag gaaataattg tgaacgaaca aatgtcttag cttgcgtatt catcatggtc
    13681 actccttata ttgcttttac ttcttttgat agcctttgat acttttcttt tgtggaaggt
    13741 ttgtataata caataacacg tccaatgatt tggacgattt cgcaatctat ttctttttct
    13801 aatacttgag ctgcttcttc tgcaatctca tctgtatttt gaagtaacga tactttgatc
    13861 agttctcttt tttctaaagc ttcttcaatt tgaacgatca ttgctgaatt gatcccacct
    13921 tttccgattt gaaaaatcgg ctgaagatga tgcgctttgc tacgtaaaaa acgcttttgt
    13981 tttcctctta aactcataat tttccttctt ccttaaatca atgctttgcg tttcaataca
    14041 tctacaccct ttggcgccca gcccgcaatt actactggcg ctgttacagt gatccagcct
    14101 agaccggcaa aaacgatgtc tgttttttct ttcacagaaa actcaaaacg aacaagctcc
    14161 ggaaatgcct cgacttcatc aggacgagga ggctgtaata atccacctac atgtttttga
    14221 taaaattcgt ctgctttttc cagtttcgtt cgatgaatat ttacatcatt tgacacataa
    14281 gcaataaatg aagcacgatt gccgctgata aaatcaaatc ttgcaagtcc gcccaagaaa
    14341 agtgtttgcc cttcattcag ctgataaact ttaggtttga tttcttttaa cggtgcaatg
    14401 atccgcaaat cttttttacc taagtagtgc gccatttgat ggcgatggat aattcccggt
    14461 gtatcaatca aaaaatgccc gtcatctaaa ggaatctcga ttttatccaa ggtcgttcct
    14521 ggaaactgcg aagttgtgat tacatcttgt actcccgctg tatttttgat gatttgattg
    14581 ataagcgtcg attttccgac atttgttact ccgacgatat agacatcccg tccatcgcgg
    14641 tattcttcga ttttttctaa tagttccgtc atctcatgag atttcttagc actagttaat
    14701 aatacatcta ctggacgaat tcctgcttcg taagcacgtt ccttcatcca ttgtgttaat
    14761 ttagtttttt tcaatgattt aggtaatata tccactttgt tcccaactaa aagtactgga
    14821 ttgtcaccga caaaacggtg tagtcctggg attagtgaac cattgaagtc aaaaatatcc
    14881 accacattga cgatcaatgc atctttttgc cctaattcat tcagtaagcg caaaaagtcg
    14941 tcatccgtca atgagacatc ttgggtctca ttataatggc gtaatctgaa acaacgctga
    15001 caatagactt ccccggaagc taaacctttt tccaaagccg tttgcggcgt gtatcctaat
    15061 tcaccgggtt tgtttgtttg tataacggca ccacagccga tacattgtaa ttcttctgtc
    15121 attcgattcc acctcgccag cccatatcag ggtgttttgc taatagatag gccataattc
    15181 ttttttccca aaaacgatta aattgtgtct tccaactatc tgttgcgata atgggtttta
    15241 caaggatgct acgtatccct gcacgattgg ctccacgtat atcagtcata atctgatcgc
    15301 ctaccattac tatctcatca tctgctaaat ccaattgttt ctttgctatg ttgatccctc
    15361 ttgctaaagg tttcattgct cgtgcaacat acaaaagatc aaatttttca atcgctcgcg
    15421 cgacacgttt tgaattattg tttgaaacaa caacaacagg gattcctgca tttttcattt
    15481 ctaaaatcca agtaagcaac tcttctgttc catctggatt attccatgca atcaacgtat
    15541 tgtctaaatc ggtcaatact gctttgatgc ctagattctt taattgggca ggtgtaatct
    15601 gatagatggc ttctaccatc catgttggtt tgtaatttga aaacatgctg tctcctcatc
    15661 tgcaaaaaat gaaggagcac ataaagtact cctcaacccc gtattatact gcatatcagc
    15721 aaaaaaaact acctctatac tcgttcgtct ttcagaaaaa gcatttcttt acaaaatgac
    15781 caaaaataaa gattgatcac agaaaaattt agaaacaaaa aacaactaat attggcggaa
    15841 cctcttgtat cgtttttcca gtaatttatg ctgatctaat cgaacaagtt ccgtcaatct
    15901 ttcaatcaac gcttttttca taatgtgtgc gactttatat cgtggcaact gctcgccgtt
    15961 gaacgtttca ggaataactc gatcaacgat tcctaactcg cgtagttctg gcgcagtaat
    16021 tttcatcaac tcagctgctt ctgcggcgcg actaccgtct ttccacaaaa tcgacgcaaa
    16081 tccttctgga gaaagcacag cataaatcgt ttcttccagc atccagactt catccgctaa
    16141 acctagagca agggcaccgc cacttccacc ttcaccaatg atgatggcga tgatcggtac
    16201 ctttaaatca gacatttcga gcagatttct ggcaatagcc tctccttcgc cgcgctcttc
    16261 tgctcctaca ccgcaatatg cacctgctgt attgatcaag gtaatcaccg gtctattgaa
    16321 cttttccgct tgtttcatca gtcgtaaagc ttttcgatag ccttcaggat ggggagaacc
    16381 aaaatttctg cggatatttt cctgcagatc ccgtcctttt tgaataccga tcactgttac
    16441 cggtttgcca tctaatcgag cgattccacc aacaatcgct tcgtcatctg caaataaacg
    16501 atcaccatgg cattcctcga aagaatcgaa gatctcttca aaaaaatcca agcttgtcca
    16561 tcgttcttta gctcttgcta actgaacgac atcatgtgct gtcttatcca cgatctatcc
    16621 atcctttctg tgtatgcaat tcaagaagcg tatggatttt ctgtttcaat tccatgcggg
    16681 gaacaatctg atcgacaaaa ccatgagata ataagaattc agccttttgg aaatcttctg
    16741 gaagttcctg cttgatcgtc tgttcgatga cgcgtcttcc agcaaaaccg atcaagcttt
    16801 ggggttctgc tagaataata tcgccttcca ttgcaaaact ggcagttact cctccggtcg
    16861 tcgggtccgt taaaacagtt agataaaaaa gaccttcatt gctatgccgt ttgacagcag
    16921 cagagatttt tgccatctgc attagagaaa agattccttc ttgcatccgt gcgccacctg
    16981 aagctgtgaa caagacgact ggaagacttt cctttgttgc tcgttcgaat aatctggtga
    17041 tcttttctcc gacaatcgtt cccatacttc ccatgataaa attaggatcc atcactccaa
    17101 taatgaaggg aatcccctga atggttgctt taccagtgag gactgcttca tgaagtcctg
    17161 ttttatcttg cattttttta attttttccg tatattcggg aaatgctagc ggatctttgg
    17221 ttacaagatc cgtatcccat tcttcaaaac ttttttcatc aataatcaaa gctagacgct
    17281 gccatgcacc gattcgaaaa gcgtatccgc aatgagggca tactttttct tcaccgatgt
    17341 ctttcgtata aaggatatgt ttgcaatttg gacactttgc ccacatgtta tcaggaacag
    17401 atggcgagtt agcaggtttg ctctctctat taggattgat ccgaatatat ttctttttct
    17461 taaacagagc catctatgcg cctcctatct ccgtttctgg tgtccaattc ggtaaaaatt
    17521 cttcttgtaa aaatgctgtg ctgtaatcac ctgctatgac tgcaggatga ctaatcaaat
    17581 ccatctgaaa ttctgcgttc gtgatgattc cttctgtgat aaattcactt aaggctcgct
    17641 gcatcttcat taatgcttca aaacgcgtat ttccatggac gattattttt gcaatcattg
    17701 aatcataata tggcgggatc gtatatcccg ggtaaactgc actgtctact cgcagtccca
    17761 tcccacctgc tggaagcagt aagttttgga tcttccctgg agaaggagca aaatggaaag
    17821 caggattttc tgcattaatc cggcattcga ttgcgtgtcc ttggaatact acttcttctt
    17881 gacacacatt caaaggctca ccggctgcta tctccacctg tttttttact aaatcgattc
    17941 ctgtgaccat ttctgttact ggatgttcca cttggattcg agtattcatt tccatgaaat
    18001 aaaaatcgcc ttcttcatcc atcagaaact cgatcgttcc ggcattttca taattgactg
    18061 ctttagctgc tcgaacagca gcgtctccta gtgcttctct ttttgtttgt gagatcacta
    18121 cagaaggaga ttcttccagt actttttgat tgttgcgttg taaagaacaa tctcgctcgc
    18181 ctaaatgaat gacatgacca aatcgatcac ctaagatctg aacttctata tggcgagcag
    18241 gataaatgat tttttccaaa tacatatcat catttccaaa tgccgctgct gcttcttgct
    18301 gagctgaaga aaaatgctgt gggagctctt cttttgattg aactttccga atgcctttcc
    18361 cgccaccacc tgcagctgct ttcagcatca ctggataacc aattctgtct gctatttcca
    18421 atgcttcttc tactgtagat aatacaccag tacttcctgg aatgactggg acatttgctt
    18481 cttgcatcaa ttgacgcgca ttgatcttat ttcccattgc atcgatcgtt gcacttttag
    18541 gaccaataaa tgtgatattg cactcttcac acatggaggc aaatcggcta ttttcagata
    18601 aaaaaccaaa tcctggatga attgcttcgg cttttgtcac gattgcagcg ctcagtactt
    18661 cctgaacatt cagatatgaa tcaacggctt ttgccgggcc aatgcagatt gcttcatctg
    18721 ctaactgtgt atgaagtgct tcggcatctg cttctgaata tatcgctacg gtttggatcc
    18781 ctagttcgcg gcatgcacga atgatacgta cagcgatttc accgcggtta gctatcaata
    18841 ctttagaaaa catatttcac ctatccaatc ataaaggtta attccgcttc ggctactttt
    18901 ttaccgtcta ctttagcgat tcctttgcct attccggctg aagctttcac tttcaatatc
    18961 tcaacttcaa ggtataaggt atctcccggt gtaactttct tacggaattt tgctttgtcc
    19021 aatccgccga aataagccgt ctttcccttg aattgttcaa gagaaagtaa tgcaactgct
    19081 cctgcttgag ccattgcttc aacaatcaat acccctggca taacaggttc ttctggaaaa
    19141 tgtccttgaa aaaagggctc attgatcgtt acatttttct tagcaacgat ccgttctcct
    19201 tcaaccattt cttccactcg atcaatcaaa agcattggat aacgatgtgg aatgatttct
    19261 tttatttctt gtatgttcat tgttttccct ctttcctgct ttgcttattt ttgctgaatc
    19321 ctaaagagtg gctgtccata ttcgacaact gactcgtttt ctacaaggat ttctgtgatc
    19381 actccgtcgg cctcactagt tatctcattc atcagtttca tcgcttcaat aatgcagata
    19441 acttctcctt tggcaacttg atcacctact tttttgaaag ctggtttgtc gggcgctggt
    19501 tgcagataaa cgattcccac gattggcgaa acaacctcga ttccatcaaa tactgccgat
    19561 tctttttctt tcattatttc tggagcagtt gttgcttgtt caggtatgac attgactggc
    19621 tccgaaactg gcaacgtttc gtttgtttga accatattca tgcctcgact tgttttattt
    19681 ttattcatat acaattcaaa ttgaccttca cgcaaatcga attccgttag cgaggattga
    19741 tcaaattgac tgactaattc tctgatttca ttgatatcca aaattattcc tcccagcgtt
    19801 tcatgcacag aaccgcatta tgtccgccaa accctaatga attactcatt gcataagtaa
    19861 aacttgcagg tttgctttcg tttttgacaa ctgtcaagtc aatctcagga tcttgttttt
    19921 ctacattgat cgtaggtggg ataaattgat gttctaatgc cagcaaagtt gccaaggctt
    19981 cgatcccgcc ggctgctccc aataaatgtc cagtcatcga tttcgtgctg ctgacgtaag
    20041 tatctctgaa attttcacct aatgcgattt ggattgcttt tgcttctgcc tggtcattgg
    20101 ctggtgtact tgttccgtga gcattgatat atccgacttg ttccggctgt acaccagctt
    20161 cttccatcgc aagcttcatt gctttagatg caccagaacc atctggagta ggagctgtca
    20221 tatggtaagc gtcacagttt gcaccgtatc caacgatttc tccatagatt ttggcaccgc
    20281 gagcttgtgc atgttctaaa gattcaagaa ctagaacgcc tgctccttca cccatcacaa
    20341 aaccattccg attttcgtca aacggaatcg aaccacgatt aggatcagtt gattctgaga
    20401 gtgctgttaa agctgcaaat ccagcaatcc ccatctcaca aatcgttgct tctgttcctc
    20461 cagcaagaat gacatcagaa tagccatgtt tgatgttacg gaatgcttcc ccaattgaat
    20521 tcgttccgct agcacaagct gttacgatag ctgtacaaat accttttgca cctacacgca
    20581 aagcaatatt tccagctgcc atgttggcaa tcgccattgg tacgaacatt ggagaaactc
    20641 gttttgcacc tttttcatgt agacgaataa cttggttttc gattgttgga agaccaccga
    20701 tcccagatcc gatgatgacg ccaaaccggt cttgattcat tttttcttta tctaaaccgc
    20761 tcatctccat tgcttctaaa gcagcgtaga ttccatagat cgaaaacata tccattcgtt
    20821 tgctatcttt tttaataaaa tatttatcgt aagggaaatc tttgacttca cccgctaagg
    20881 taatccctgt ttctgaagca tcaaatttag tgatcggtgc gatgccattc gtcccctctt
    20941 ttaagctatt caaaaagctg tctgcgtcat ttccaatagg tgaagtgact ccatagccag
    21001 taattaccac tcgattcatt tgtttgctct ccttttctta tccgtgcatg accaatccgc
    21061 catcgacatt gatgacttgt ccggtgatat atggattttg tgctaagaaa actgctgttt
    21121 gtgcaatatc ttctacttgt ccgaaacgct gcatcggaat ttgcttttcc gcttgttcct
    21181 tgactttgtc tgctaaaact tccgtcatat cagttgtgat gaatcctggc gcaatggcat
    21241 tacatgtaat gcctctagtt gcagcttctc gtgccacaga ttttgttaat cctactacgc
    21301 cagctttact agctgcataa tttgcttgac caatatttcc aatcaaccca gatacactag
    21361 agagattaat gatggcccct tctcgctgct tcatcatttt tttcaatacg tgctgcgtca
    21421 tattgaaggt tccaatcaaa ttgatatcca gacatttttt gaaatcttct gcatccattc
    21481 gcatcacaag tttgtcattt gtgattccgg cattgtttac taacacatgg atcgatccaa
    21541 gcttttcttc tgcttctttg atcatttgtc ccgctttctc ataatcagag atgtcaccgg
    21601 aaactcctac gcattttaca ccgaatgctt cgatttcttc tatcttttct tttggaatct
    21661 ctccgcgacc attcaaaatg atatttgctc cagcttttgc aaaagctaag gccatcgctt
    21721 tgccgattcc tcttgtacta cctgtgataa atacattttt tccttttaca tccataacgt
    21781 tcctccttat agtattgcta ttgtttcatc aaatgtctgc ttattctcaa cacgcagaac
    21841 tggtattgtt ttatcgattt ttttcataaa tccgcttaat acttttccgg ggccgacttc
    21901 gatgacttgt tcgatgccga ttgtttttaa cttatggata ctctcataga aacgaacagg
    21961 ttgcatgact tgctgttcaa gtagtcccgc gattgtttct ttcttcatta tttccgttgt
    22021 tgtgttgctt atgataggaa aagaaggttc agagaattga atctgactta ggtccttcgc
    22081 cagttttttt gctgccggtt ctaaaatagc tgtatgaaaa ggcccgctga catttagagg
    22141 gatcattctt ttgaaccctt tttcttttaa tagtaaaaca gcttcgtcta ctgctttttc
    22201 ttcgccacca atcacgatct gctgaggtgt attataattt gcaggagata cgatgccgta
    22261 cttgctagct tcatgacagc tttcctcgat cgtttcaatc ggcgcattca tcactgcaac
    22321 cattttcccg cttccagctg gggcagcttc tgtcatataa gcgcctcttt ttgctactaa
    22381 cgcaactgct tcagtgaagg atagcgcatt actagctact aatgccgaat attctcctaa
    22441 actcagtcct aaagctgcat ctgggatgat tccatgctcc ttcaataagc gataatacgc
    22501 gatgctgact gttagaatag ctggctgtgt atattgcgtc tgatccaaac gttcattttc
    22561 tgtaaagcaa agttcagcca tatcgtagcc gagaatctca cttgcttcat caaatgtctg
    22621 ctttacaacg gcttcttcat ataaatcttt tcccatacct tgatattgtg caccttggcc
    22681 actaaataag aatgctgttt tcatgttttt ctccaatata tccagaatat atgtttgatt
    22741 cttcctattc aaaaaggccg agacattcct atttcaggaa atgtcccagc ccccaaccta
    22801 attttaatga ttatgcagtt tgtttttcta cgtaagtcac taaatcttga accgttttga
    22861 ttccgtcttc tgtttcgatt ttcacgtcaa attcatcttc aatttcattg atgatttgga
    22921 ataaatccaa gctgtcagct tctaagtctt cttggatgtc agtagtcaat ttgatttctt
    22981 cagtttcttt tcctaattct tctgcgatga tttcttgaat tttttcgaat accataataa
    23041 tatattcctc cgatattgtt tgctttttat ttttataatt taacagtcta caactccatg
    23101 agaatacttc cccatgttaa acctccgcca tagcctgtaa atattacttt ctgctgtttt
    23161 cctaaggtga tctttccact agaaactgct tcatccaata agatagggat gcttgcagca
    23221 gatgtattcc catatttatc catattggtc aggaactttt cttgcggcat ctttactttt
    23281 cgggcaattt tctcaataat tctgaggttt gcctgatgca aaagcagata atcaactggt
    23341 ttgtctttca tgacttcttg gatattgttt gcaacgtctc gtacggcaaa atcaaaaata
    23401 tctctgccag tcatttgcaa ataatacgaa ccttctgaat cttctgaata gaacggattt
    23461 ttattttgct ggtagccagc ggtcaatgag ctacttctgg taccgtcagc tgctaatttt
    23521 tctttcagca attttttctg tggattcgct tctaagagaa tcccacctgc tccatcgcca
    23581 aacaacacag cagtcgtacg atcagaccaa tcgattagct tagatagtgt ttcaccacca
    23641 atcaccagtc ccttagttga gccgcagcgg atcatttttt cagccatgct taacgcataa
    23701 acaaatcctg agcacgcagc actgatatca aaagcgatag catgagttgc tcccaatttc
    23761 ccttgtactt gtgctgctac agatggtgtc gtgtaatcgg gcgacattgt tgctactaaa
    23821 ataaaatcca aatctttagg gtttagattt ttctgtttta tcaatttttc cgccactaaa
    23881 atgcataaat cagaagtctc ctgatttgtt acacatcttc gttcacgaat acccgtcctt
    23941 gacgaaatcc attcatcaga ggtatccatc atcttggaaa gatcattatt agtaataatc
    24001 ttttcaggaa ggacgctggc tgttgcagta atcattccaa attgttccat taaatatcct
    24061 cacttatagt cttgcaagaa gtcgtgcaag tttttcagtg catccagcaa ggcatgctgt
    24121 tcctccgtag ccattccgtc taagatgttc ttgaccattt cacgatgaaa atgctgatgg
    24181 acccgaaata gtaactttcc ttttttcgtt agtcccaact ttacaacgcg gcggtcatct
    24241 tcactgcgga tacgttcgac atagcctttt tttactaact tgttaatagc agtggtcaag
    24301 gtcccaacag taattgatag ttctttggct acttctgaag ttgttttttt cttgtacatc
    24361 ccgattgcct cgatcgtgtg catctctgtg attgacagat ctttgaattg agattttttc
    24421 agctcagact cttcgattgt caaaatatca ttgaagacac taacaagata atcatttact
    24481 gtttttaaat ctggttccat gttccaccgt ccactaatta gtttgattat caaatctttt
    24541 gatgttcaaa ctatatctta acttttttca aaatgcaacc ttaaaagatc atttttttac
    24601 tatatgagct ttttttaaga ttttactcat ttaaaacaac tgataaatca gcatttataa
    24661 tttcttttat tagaaaaatc atctatctca catattttga ttatcaaagt attttctgtg
    24721 aacagaacta tagaattccc taaaacttgt ccattatttc aaaatttgtt atagtctttt
    24781 tattcaaagc gtaaaaggag atcctatgtt aaaagaaaaa atgaaaactc tccccatgct
    24841 gccgggtgtc tatcttatga aagaccgaga tggtaaggtc atctatgttg gtaaagcaaa
    24901 acggctcaaa aatagagtaa gcagctattt tcatcagaat aaacagcatt caaaaaaagt
    24961 attacgtatg attcatcata taacagattt tgatttcgtc gtagtagaca cggaattaga
    25021 tgctttattg ctcgagtgtc aattgatcca acattaccgt cctttttata accgacaaat
    25081 gaattatttc agtaattata attatgtaca tattaccaat aagggatttg tattaacaga
    25141 tactcctacg gctcgaacat acgggccttt tcgtctctat aaaaaaatgc cgtctatttt
    25201 gcgtataatg gaagaaactt atcaaatgcc ttggttgtct gaaattagtt tgttagcttt
    25261 gcgagtccag cttcctgacc tacaggaaat gacttttgaa cagaaaaaaa aggaactcca
    25321 agggctgttt caaggccgaa ataaaaagct actgacttac ttgaaaaaaa gacaacaaca
    25381 tttcatctat cagttgaatt tcgaaaaagc cggtatgctt caaaaagata tcgaattagt
    25441 tacttatttt attagacgga tccaggaaca aaagcagttt ttaagaacac catcgctcac
    25501 cttcagcatg ccattagcag cagatgagag tcagaaaaag cactacctcg tttgttatgg
    25561 tcaacttgca gaaacaatga ttacctctgg tgacgtttct cctgacttct attatgaaaa
    25621 gaaagaagct catttatctt tgaaacgtca attgtcaaaa gaagaaatcg atcctgtaca
    25681 aatcttgatc agttaccgca aaaaattaga aaaagaacag tttgaaattg aactgttaaa
    25741 caaaaaagaa gctgaaaagc aactaaatta gttgcttctc ggcttctttt aggcatcttc
    25801 aacttcaaat gtcaattatc ctaaaattta ttggattaag tcatagattt ccatcgctac
    25861 gatatcgata ttatcaaatt cgtattgctg atgagtatct gtttcagtta attcaaatgt
    25921 atcggtcgct ttatcataag ttactgtaca cttctctacg ccttcttttt caaaacggcg
    25981 aacttgcagt tcattatctg ctgactcgac catagcctcc agtcgtttta tgattgcgac
    26041 taattgtgaa tgtgtcatcg gaggtcctcc ttttcttatt tctgttatat tgtatcaaaa
    26101 gcatagccta cttgcattga ttttctctaa aaaaactcgt tttttatgat tttttttctg
    26161 gtatttttcc ttcaggccac caaagtttga tcaaagcttg ggttccgtca ttctcaaaac
    26221 ctttatctgc caactcttca tatagtttca atgcttgggt agttgctggc aatacaagat
    26281 ccattttttc tgcttcttct aatgcaatct ttaaatcttt gataaaatgt ttgacaaaaa
    26341 aaccaggtgt gtaatcttct tttaaaatac gaggagaata attgcttaaa gaccagttag
    26401 ctgcacttcc acctgaaagc gtctcaatca ctttctttaa atcaagtccg tttttttgtg
    26461 catagacaag catttccgtc attcctgtca tcgtacctgc aatcatgatc tgattagcca
    26521 tttttgtatg ctgacctttc ccagcagaac catgcaatgt aaatgtcgta ccaaattctt
    26581 tgaataaagg cagtacttga tcataaacgg cttcttctcc accgaccatg atcgtcagtg
    26641 taccattctt tgctcctaag tcaccaccgg ataccggtgc atctaacgca tctgcgcctt
    26701 tttcttttgc tgtttttgca attttttctg ccaggcttgg tgtacttgta gtcaaatcaa
    26761 ctaaaatatg tcctgagata tctgcagaaa aaatccccga ctgtccatag tagatttctt
    26821 ctacatcttt ggggtaacct accattgtaa agagaatatt actttgttct gctaccgctt
    26881 ttggtgtatc tgcccagata gctccttctg ttactaaagg atcagctttt gcttttgtcc
    26941 gattatagac agctacttcg tgtcctgctt ctagtagatg gcgtgcgaca gcacttccca
    27001 tgacgcctgt tccgataaaa ccaagtttca ttttttcgac ctcctaaaaa tcaaaaatcc
    27061 ttgcttctat gctagtatac gctagaaaca aggatttttt cataaaaaat gtttgaattt
    27121 tatcttttaa atgaatttaa ttttattttg attcgttcaa tcgagtcttc ttcttctttt
    27181 cttcgcatct cttcttcatg ataaacaacc atgtcttgat aaaattcgat catagcttcg
    27241 ccgaaatgtg tagatgaaat atcataaagt ttagcttcta aaacttttgg atctttagga
    27301 acttcactgg aaatataatc aataagtgct ggtgcaaagt cttcgtcggt ttcaaaagtt
    27361 ttccctaatg aaggatgatc gaacaatcgg ttcaaataag catttccttc cacgacacaa
    27421 ggtgttccgg ctgccatcgc ttctgtataa gtaagccctt gtgtttctga agtagaagca
    27481 ctgacaaaat aatctgccgc tttataataa agtgctacat cattgttgtc cacttctcct
    27541 gtgaactgca caaattcttc taactgcagt tctgagatca attcctctaa ctcttctaca
    27601 taaggtcctt ttcctacgat aactaatctg gcgttaggat aagcggagat gacctgagga
    27661 aacccattaa tcaaggcttg gatatttttc tcataagaaa tcctgcttaa agaaagaatc
    27721 atcaaatggt tttcctgaag acctagtgac tcccttaatt tgctgatatc ctgctgagtg
    27781 atatcagaac gtttgaattt ttcaatgtcg ataccagtag gaatcacgcg aagcggtgct
    27841 attacaccat agctgcgtaa tgtatcaata acacgttcac ttggacaaac tacacctgtc
    27901 gtatgatttg caaataatct agacaagtat tttacatggg attgcctgat cacttttcct
    27961 ttaccgatat aatgaaggta gtcttcatac atcgtatggt aagtatggat cagaggtatt
    28021 ttcaacttct tagctaccat cttcccaagt atccctgctc cgaattctgt atgggtatga
    28081 ataagatcta gttctagttc tttggcaacc aaataagcat accacatgcc tctaacaaca
    28141 actcttcgat ccttgaaaga aataaatggt acacttggca ttcgaatcac atctttttcc
    28201 aacttatccg cattaggatc ggtcgttgta aaaatataga cttcatgccc atgtctttct
    28261 aattcttgtt ttaatgtttt gatcgatgta gcaactccgc tgacttgcgg aaagtaggta
    28321 tcggtaaaaa agccgatttt catgtttttc gcctccaaac tagtccttga cctgatttac
    28381 tttttttaat ttgctagaga ctttttcatt cagtacactt tcgtatacat ttttaagttc
    28441 ttcaccgatt ttattgatac ttcgctcttt tgctgtttga taaccggctt gtgtcgtact
    28501 cggtagttct tgattggtaa tctgttggat cagtcggata aattcttcgt ttgtcttccc
    28561 catatagcag ttcttgctat cttctaacca gccattatac actggaatat ctcgaacaag
    28621 tacgttttgt ttgcttgcta aagcttctaa aacaacgatc ccttctgtct cttcataaga
    28681 agggaaaaag aatagatctg cacctgaata cgcaccttct atgatctctc cacgaatgta
    28741 accaggaaac aggacatttt caggatgatc ttcttttaca attttccgga tgttccgagg
    28801 aatcgagtac atgggaacat gaccaaacca aataaatgtg tattcgggca tcttcttagc
    28861 aatttctacg aaatcaatga ttcctttacg ttcgaaaaac aaaccgacac aaatgattac
    28921 tttttgatcc ggagacagtt tgaaatattc tctgaacttt tgttctttca ttggatcagg
    28981 gtgatatttc tctaagtcga tcccattgga aatagcttga atcggcacac ggataccata
    29041 gctttccaac aactgttttg aataaggtgt tggcgtgatc agatagtccg ctttttggta
    29101 caatcctacc agatattttt ttacgatagg agaaagctgg ttcgatctga taaaggaatt
    29161 tcggaaatct tcctctgtag aatgcgcatg atagacaact ttttttcctt ctcttctggc
    29221 tttattgacc atattatgac tattgattcc gtatgtattg atgtgcagga tgtcataatc
    29281 ttctttttca tctagtgtat aagagatacc gacttccgtc agagcacgtt tttgatgatc
    29341 aagcgcacgc ccgattccag attttgcaag catcttttca ctttcaaaat ataataatac
    29401 cttcacctta cgtccccctt cacttatata gtataacata gcctacaaac tgtcactcaa
    29461 acttaagccc tatttttgtc tattcttact gacaaaaacg ttttcttaaa aaagaacaaa
    29521 aaaactggcg tagctctttt acaagccaca ccagcttttg atacgttgtt tattttacat
    29581 attcatgaac aagttcaacg acttcttcca tcatatcgca ttctttcaat gcacgatcag
    29641 caagttcagc cattttcgct gtgtccaagc gtttcattaa actacgcgtt ttaagaatag
    29701 atgtcgcact cattgagaac tcatctagac ccatacctac tagcaatgga acagctgttt
    29761 gatctccagc catttctcca cacatacctg cccattttcc ttcagcgtgt gctgcatcaa
    29821 ttacattttt gatcaaacgt aaaattgatg ggttatatgg ttggtacaag taagaaacgc
    29881 gttcgttcat acggtctgct gccattgtgt attgaatcaa atcgttcgta cctacagaga
    29941 agaaatctac ttcttttgca aacttgtctg ctaagactgc tgctgctgga atctcgatca
    30001 tgatgccgac ttggatcgta tcagatactt ccttgccttc acttatcaat ttttgttttt
    30061 cttcttcaaa gatcgctttt gctgcgcgga attctttgag tgtagctacc atagggaaca
    30121 tgatacgtaa attaccatga acagatgcac gaagcaatgc acgcatttgt gtacggaaca
    30181 tttcgtcgcc ttgttcagat aaactgatac gcaatgcacg atatcctaag aatggattca
    30241 tttcatgagg taattgcaga tatggtagtt ctttatctcc accgatgtcc attgtacgaa
    30301 caactacagg ttttccttcc ataccttcta atacagcttt gtaagcttca tattggtcat
    30361 cttctgttgg gaagtctgga gaatccatat acaggaattc agtacggtac agaccaactg
    30421 cttctccacc attattatgg acaccaacta gatcttttgg tgttccgatg tttgcagcta
    30481 attcaaaatg cttgccgtca gctgtgacag tttctgcatt ttttaatttt tcccattctg
    30541 ctttttgtgc tgcgtaatct gcacctgctt tttcaaattc agctttttgt tcatctgtag
    30601 gatcgatgat tacatcgcct tcgatcccgt tgacagccaa aatatcgcct tctttgactt
    30661 tagcagtaat ttcttttgtc ccaacgattg ctggaatttc taaagaacgt gccatgatag
    30721 cagaatgtga agtacgtcca ccaatgtctg ttacaaacgc ttttacaaaa ttgcgatcta
    30781 attgtgctgt atcacttgga gtcaagtcat gtgcaacaac gaccacttct tcgttgatca
    30841 ttgatggatt tggtaaagta acgcctaata agtgcgctaa aatacgttta gcaacgtcac
    30901 gaatatctgc agcacgctct tgcatataag cattatcttc cattgcttcg aacataccga
    30961 tatacatatc cgttacttct tttagcgctg attcagcatt tacgctgttg tctttaatat
    31021 tttgcttgat ttgacctacc atttctggat ctgaaagaac catcaaatgg gcatcaaata
    31081 cttgcgcttc tgcttcacct aagctttgcg ctgctttttc acgaatttgc tgcaattctt
    31141 cagtagattt agctaatgca gcatccaaac gagcttcttc agccgcagta tcttctactg
    31201 ttgccttact gaatgttaaa tccggttgaa ctagcaggta agcttttgca acggctacac
    31261 cgtcactagc ggcaatccct tttagcattt caaccattat tcagataagc cttctttctt
    31321 cattgtttca acgattgctg ccattgcatc agcttcgtca gcaccttctg cagtaatagt
    31381 aacatcagaa ccttgaccta cacctaaaga cataacgccc atgattgatt tcaagtttac
    31441 tgatttacct ttatactcta agtttacatc agagttaaat ttgcttgctg tttgtactaa
    31501 tagtgtagct ggacgagcgt ggatcccagt ttctgctact acgtgaaatt ctttcttttc
    31561 catattaatc ggtctccttt aagtgagtgt tgtttttatg tgagggtttt cttttttagt
    31621 aattcagaga atcctaacaa atgccaccct ttcatctgta aagattaaca ttttttttcg
    31681 ttagatacaa cagttttcat tcaatttcag ataaaagtat tcaaattatt ccggattctt
    31741 tttcatcctt ttcttcacat tttataacaa acgtgtttat ttcctttttc ttgtcgcttt
    31801 ctcttctcct gacgtttatc attctttcct ttgaccctct ttgttttcat atgaaacgaa
    31861 ttacttgctt ccctttttat ttttagtata ataagagtca aaggtcagga atggtcaata
    31921 gagatttcac cttttctacc tcataaatct cttaaaaaac taggggttat tcttttacct
    31981 catgaaaaac gagatgtaaa atatggatgt acccattttt gtgaaaggac gtgaatgatt
    32041 catgctttgt caaaactgcg gcaagaatga ggcaacgatt cacttgtatg ccactgtcaa
    32101 tggtcagcgg acacaactcg attactgtca gagctgttat caaaaaatca aaaatcaaca
    32161 aaatggaggt ctgactaata tggcccaaaa tgatccattt ggatttggca gtttggacga
    32221 tcttttccgt tccatgtctc gccaaatgca acagcaagga aattatgagc aaacaccacc
    32281 aacacaattt ggcggaaaca acaacttcaa tggtggtcag ccacctcaag gcaatacaga
    32341 aggtttattg ggagaatacg gaatcaatat cacagaacaa gcacgacaag gtgatatcga
    32401 tcctgtgatc ggacgcgatg acgaaatcaa acgagtcatt gaaattttaa atcgccgaac
    32461 caagaacaat cctgtcttga ttggagaacc aggtgttggt aaaacagcag ttgttgaagg
    32521 tttagcacaa aaaatcgtag atggtgatgt accgcaaaaa ttaatggaca aagaagtcat
    32581 tcgtttagat gtcgtatctt tagtccaagg tactggtata cgaggacaat ttgaagaacg
    32641 tatgcaaaaa ttgattgaag agatccgtca agcagaaaat gtgatcctat tcatagatga
    32701 agttcacgaa atcgtcggtg ctggttctgc tggtgatgga aatatggatg ctggtaatat
    32761 tttaaaacca gctttagctc gaggagaatt gcaaatggtt ggtgctacta ccttaaatga
    32821 gtaccgcatc atcgaaaaag acgctgcttt agaacgtcgt atgcaacctg tacgggtaga
    32881 tgaaccaact gtcgaagaaa cgatcagtat tttgaaaggt ttgcaaaaac gttatgaaga
    32941 ctatcatcat gtaaaatata ctgatgaggc catcgaagca gccgcaactt tatccaatcg
    33001 ttacgtccaa gatcgcttct tgccggataa agccatcgat ttgctagatg aaacaggttc
    33061 taagaaaaac ttgacgatcc aaatcgttga tcctaaaaca atcgagaaaa aactgcaaga
    33121 agcagaagaa caaaaagttt tagcttctcg agaagaagat ttcgaaaaag cagcttatta
    33181 tcgcgatcag atcaataaac ttcaaaaaat gaaagaacgt cagctcactg aagaggaaac
    33241 acctgtgatt accgaaaaag atatggaaaa aatcgttgaa caacggacag gtattccagt
    33301 gggtgaatta aaagaaaaag aacagacaca actgaaaaac ttagcagatg acttgaaagc
    33361 tcatgtcatc ggacaagata acgctgtaga tcgagtagcg aaagcgattc gccgaaaccg
    33421 tgttggatta aacaaacaga atcgtccaat cggctccttc ttatttgttg gaccaactgg
    33481 tgtaggtaaa acagagcttg cgaaacaact tgcctacgaa ctattcggtt cacaagattc
    33541 aatgattcgt ttcgatatgt ctgaatatat ggaaaaacat agtgtctcta aattgattgg
    33601 ttctcctcca ggttatgtcg gatacgaaga agctggtcaa ttaacagaaa aagtacggag
    33661 aaatccttac agtcttgtct tgttagatga agtagaaaaa gctcatccag atgttttgca
    33721 tatgttcttg caaatcttag atgatggtcg attgacagat gcacaaggaa gaacggtcag
    33781 ctttaaagat acgatcatca ttatgacaag taatgccgga actggtaaag tagaagcaaa
    33841 cgttggtttt ggtgcggcac gcgaaggtgt tactcgttct gtattgaacc aattaaacaa
    33901 ctactttaca ccagaatttc tgaaccgttt tgacgggatc atcgaattca gtgcattatc
    33961 aaaagaaaac ttgatgacaa tcgtcacact aatgctagac gatgtcaacc aaatgctggc
    34021 agcacagcaa cttcacatcg aagttcctac gaatgtcaaa gaaaaattag ttgacttagg
    34081 ctatgatcca tctatgggtg ctcgtcctct tcgacgcacg atccaagaac aaatcgaaga
    34141 tggtatcgct gaattttatc ttgatcaccc ttctatccat gagttgaaag caaaactgga
    34201 taaagatgga aaaatcatcg ttacttctaa accagaacgt ttggctaaag aatcagccga
    34261 agaaacggct gaataaatcc agttttatag cgtgagacgg tatttctttg agaaatgccg
    34321 tctcattctt ttttcagaaa agtcaaaata ctgttcattt tataaaaaag aaattataat
    34381 aagagaaaca agcaattaaa aatacataaa agaggtgagc gccatgaaat tggtaaatgt
    34441 aacaaacagc cattcccgtc ttgtattaaa ccagcttgaa aacactgatg cccatctagt
    34501 caaggtctac acagccggaa ataccactat tgtctacact gaagcccctg aacataatga
    34561 aattctgctg atcaatgaca aacgtaaaat ccagccgaaa gaaatcgaag atgctaaaaa
    34621 ttatttctta gataaaatca aagacgccgt ttaccacgag gatgaaatca aagtaatcga
    34681 attggcaggc cttgttgaaa tctcgattcc aaaacatgaa ttaggcgcta cattagccgt
    34741 gtaaacaaat tttgaacata ataattaaag agcgtgggac aaaagtaaag aacacttttg
    34801 tctcacgctc taaacacgta taaacggcga aagcagaagc aactccttcg gaaataagct
    34861 gaaattcacg aaaattgctt ttcaaatttt tgtgaattcc agcttatttc ttggagttaa
    34921 acgcttctgt ctcagcctct ttttctttct agctttttga tttttctctt ttcttttgta
    34981 cttttctctt ttcattttca gttctacgcg tgtctttatt tttaactttt tcctctttat
    35041 ggatgattga tcgtactttt tgtgcaattt gctcgttttt gtcccagtct tttacatcta
    35101 ataatcgaca taatcgtaac atctcttctt ttttctgttt ttttctttca cgtctttgcc
    35161 attctgtttc catgtgtcac actctccttt ctttaatcat atgtacgcaa aataattttt
    35221 atattttttt gattagacat ttctatgatt ttaatatagt aaaaagagcc gtcacggaaa
    35281 atccgtcacg gctctaaaca aaatatgaga ggctgttttt gtttggctat tcttattact
    35341 tgatgcaggg cagcttgtgt caagacttct ttacatcaaa ctttttaatt ttacattggg
    35401 atatttatcc gcaaaccagc gttctgcaaa ttggttctcg aataagaaca acggttggtc
    35461 gaaacggtca cgagccaaga tattgcgact tgaactcatc ttctcatcca aatcttctgg
    35521 atcgatccag cgagcgattt tgtgtcccat tggagacatg attacttcgg cgttatactc
    35581 atttaacata cgatattgga atacttcgaa ttgtagctga ccaacagctc caatgatata
    35641 ttcttccgtt agatatgttt tataaagctg aatcgctcct tcttgaacta attgatagat
    35701 tcctttgtgg aaggattttt gtttcatgac attttttgca gtcactttca taaacagctc
    35761 tggagtaaat gaagggagtt cttcataagc aacttttagt tttccttcga acaatgtatc
    35821 cccaatctga taattgcctg tatcatatac accgatgata tcgcctgcta ctgctttttc
    35881 gacgttttct ctcgaatctg ccataaattg tgtgacattg cttaatttca gttttttatt
    35941 tgtacgttcc aaccagacat ccattcctcg ttcgaatgtt ccagaacaga ttcggacaaa
    36001 agcgattcgg tcacgatggg ctggattcat atttgcttgg atcttgaata cgaaacctga
    36061 aaattcttcc tcataaggac ttaccatctg atcatcttgt gttttgtgtc cataaggagc
    36121 tggtgccaat tcaacgaaag tctctaaaaa agtctgtaca ccgaagttag tcaatgcaga
    36181 accaaaaaat actggtgtct gatcgccacg agcaattttt tcttgattaa atgcatctcc
    36241 agcctctttg attagttcta cttcttctaa gacttgttca tataaggaat tttcagttag
    36301 aggatgattt tcgggaagca gtccatcttc atccaattct actaatcgtt catcctgata
    36361 attttccgga cgataaaact ctacacgatt atggtagata tcataaagac cttctagccc
    36421 tttacccata ccgattggcc aattcatcgg ataagattcg atatctaata gctcttctaa
    36481 ttcttctaac aattccaatg gttcacgacc atcacgatct agtttgttga taaaagtaaa
    36541 tatcgggatg ccacgttttt ttacaacttg gaataatttc tttgtctgtg cttcgatccc
    36601 ttttgcacta tcgattacca tgaccgcact atccacggcc atcaaagtac gataagtatc
    36661 ttcagaaaaa tcttcatgtc ctggtgtatc caagatattt actcgtttcc cttgataatc
    36721 aaactgcata acagaactag taacagaaat cccacgttgt ttctcgattt ccatccagtc
    36781 tgatttggca aaattacctg tttttttgcc ttttacggtc ccggcttgac ggatagcccc
    36841 accaaacaat agtaattgtt ctgtaatcgt tgttttccca gcatccggat gggaaatgat
    36901 cgcaaaagtt ctgcgattgt ccacttgttg ctttaatttt ggattattca taacctaact
    36961 ccatttcttc cattcaatta tttatatttt ctctaggcac agattgtccg atctcttaaa
    37021 gaaagacaat ttcatatagg gctgtgacaa aagccgtgta gcagtctctt tttccgagta
    37081 aacggcgttc tagagacagc ctatcagcaa taagcccacc caagccaaaa atacgaaaag
    37141 ctgtttttgc ttggctgctc ttattactta atgcaggata gctttttcac aacctttgtc
    37201 aactactaca actgaatcag tatagcatgg attcagcgaa tgaaaaagcc accaaaccat
    37261 aagagtcaaa tatttttttg tcagctgact aaaagaaaag acgtgttgct tgtttattca
    37321 agcaacacgt ctttcataac caagtttcca attatcttct tggctcgtca tcttcgaatt
    37381 cttttctgaa gtatcttcgt tcttcttcag gttccgcttc tgtttcttcc ggatcatgaa
    37441 aaatgacacg gattttaagg attcgagaac cttccatttc ttcagaaacc agcgtaatat
    37501 tatcgacatc aaacgataac ttttcgcctt catccggaat catgcctaat gctgtaatca
    37561 aataaccagc catcgtatct acatcactca tatgcagatc actgtcaaaa gcttcattga
    37621 actcatcaat cagcatacgt ccttggatga tatattcgtg ttcatcgatt ttttcataaa
    37681 gattctcaac ttcatctgat tcatcatcga tttctccgac gatttcttct aaaaggtctt
    37741 ctagtgttgc taacccaacg acgccgccat attcatctaa taaaatagcc atctgattct
    37801 gcgtcttttt catttcatat aacagatcat caataaagac cgtttcagga acgaataaag
    37861 gctcctgcat gattttcttg atatctaaat tatcaaagcc gaatttatgg gcagctttta
    37921 gtaaattctt tgtatgaagg attccgacta ctttatcttt gtcttcgtta taaacaggga
    37981 ttcttgaata gttttcggat aaaacttcat tcacattttc ttccacagtg tcgttgatat
    38041 caatcataaa tgcatccgtt cgtgggacca tgacttctcg ggcaactttc gtatcaagag
    38101 aaaaaacccc ttggagcatt tctaattctt cattattcaa tacgccttcg ttttcaagca
    38161 tataacgcat ttcatctctg gtcatttttg aatcttcatc atcaaaagtc atcggcgtga
    38221 tacgcgccaa taaacttgtg gaagcagaaa gcagccagac gaagggctta gctactacac
    38281 caatcaagcg tatcagccct gaagtgaact ttgcgacttc ttctgattta tttaaagcaa
    38341 tacgtttagg gtacaattct ccaaaaacaa tcgatacata ggtcaaaata gccagcacaa
    38401 tgatatttgc aatatttttt gccgctgtgc cgccacctaa taccggagct aaccgttccg
    38461 ataaagtatt agctagtgaa gcaccagaca aaatgttgac caaagtgatt cctacttgga
    38521 ttgtcgatag gaaattattt ggattctgca atatttttaa aagcttttga gatttcacat
    38581 ctccttcatc agctttttgc tcgattcgat tcttattgat cgaaacaaca gcaatttcgg
    38641 aagctgctaa aaaagcattg atcaatgtca aaacgatcaa taataaaatc tgcgctaaca
    38701 gcgactgact ctcagggtca gcattcataa tcgcattctc tccttataaa attaattttt
    38761 agtttacgat agaaaaaaac gtggcactat agccacgtta aaatggtatc acaaagcaat
    38821 tttctttgca ataaaaacaa gtgtactaaa actacctacg aggtcgtagc aattttcttc
    38881 ttgttttcat tttgcttgtc ttctttgacg attttgatta tataggaaat gatcgtcttg
    38941 cagattgcgt aaaaaggaac acctaagaag ataccaagca atccggcaat atttccagct
    39001 actagaagaa cgataatgat cgttaatgga tggattttca gtgatttccc aattacatta
    39061 ggataaatga tattcccatc caactgttgg acgattagca caaccacaca acaaagtaat
    39121 gcttttaccg gatcattgaa gactgttact agaaatgcag gtgctagtcc tagataaggt
    39181 cctaaatatg gaattaggtt tgtcaatccc gcaatgaccc caaataagaa agcataatcc
    39241 acaccaatta ccatatatcc taaaaatgtg aaggtaccaa cgaataaaca ttcgattgct
    39301 tgtccgctaa tgtaattagc caatgtttta ttcagttgcc ccaataactc cacaatttgg
    39361 tttcttcttt tttctgggaa aaactgttgg atgtttggca ctagtttttc tccgtctttc
    39421 aacatataga acaagatgaa tggtgctgta atgattacta cggttgccga agcgatcgtt
    39481 ccaacgatcg aacctaaact attggatact ccactaagga attgctgaat gattgtcccg
    39541 taagaaatgt ctaattgctc aaaatattta ttgatatcta cttccttgaa caaaggcaat
    39601 tcggctacct cttttaacca gctttctacc tgtttgatga aatcaggcat attagatgcc
    39661 aatgaggaaa tttgctgtac tagacttggg atgacactaa gtaaaatcca aataattgct
    39721 gcaactaaaa ggagcagcac aattgcgaca gcccatattc ttttgatttt tgctttcatc
    39781 aacagcttga caataggatt caataaatag taaagaaagc ctgcaatcag tacaggtgca
    39841 aataacgtgg aaaaaaatgt cccgatcggt tcgaaaataa agtttatttc tgatgaaatc
    39901 atgatcaatg cagctatgat caataattca agcgaccaaa acattagttt agactgtcta
    39961 agtttttcaa acaatagatt tcctcctttc tttcttacta gtatatatta tattcgttaa
    40021 aaattctttt attctttttt tatttttgaa aacttgccat actttttatt tgttttattt
    40081 tccagtatac tatacgaaag gaaggtggct agaccatgaa agttgtacaa acaaaagata
    40141 caatgagcaa tatttactta gatgctgtac ggatcaggca tcaagttttt gtagtcgaac
    40201 agggtgtgcc tttgtctcga gaaatagaca aagatgaagc ccattgtatc cacttcgtcc
    40261 tgtactcaga taaaaaagaa ccgcaaggaa ctgtacgtct tttgccttta gaaaacggaa
    40321 aaatgaaatt acagcggatg gcgattcttt ctgaatacag acaccaaggg ttaggaaaaa
    40381 tattgattga agaagcagaa aactttgcta agaatcaagg ctataatacg attttattag
    40441 gggcacagtc cacagctgaa actttttacg aaaaactagg atatacagct tacggcgatc
    40501 cttttgaaga tgctggcatg cctcatattt atatgaaaaa gactttataa aaatttattt
    40561 cgaaaaaagc aaaaaacagc aagcttttga gaaaaatctc tcactggctt actgttcttt
    40621 tttgtgttta cttacgcgac aattgcttgt aacggttata ccaaatatca atatagcctt
    40681 ccgagaacgg gccatctcca ttattgatcc agtcaaccag aatcttcaca ttttctttta
    40741 ggatgaagtc aatatcgttc gggtaattca tcattttgct gtgcatctca tattcatcga
    40801 catccaatag tcgtttctcg ccgtcaggaa ataccttgat atccaagtca tagtcgatat
    40861 atttcaaggc ctcatcgtcc agcaaaaaag gtgaagctag attacaataa taggaaaccc
    40921 ccttttctct gatcattgct attacattga accagtattt tttatgaaaa taaacaatcg
    40981 ctggttcgcg cgttacccat cggcgtccat cagattcagt gactaatgtg tgatcattca
    41041 cgccgatcat agagtgttcg cttgttttta ataccatggt atctcgccac gttcgatgca
    41101 atttgccgtc gtgcttgtaa ctttggatcg tcacaaactc tccttctttt ggaactccca
    41161 tagcaaccct tccttaagca gcattttgtg ctttgtgttt gggtgttcat tacaccgaca
    41221 tcataattat tatatcaata aaaatgagct ttgcctagaa aggattccta ttgtttcgat
    41281 ttttctctaa ctgatctacc agtttcattt ggaccttagg aaaaacgacc gaatcaaatg
    41341 catcaggctt caaccacttc gaagttttgt tctcggtaaa ttcttgttct gctccctcgg
    41401 ttgcccgtcc gtaaaaaagg agaacatgcc atttcagatg actaaaaata tgagtaactt
    41461 ctcctaaatg tcgtgtctgc caaacaaaga gttcctgctt ttcaaatggg agattttgct
    41521 cttcttctgc tactaggtca tcaaacagat cgatttctgg ctttgtttcc cattcttttt
    41581 tcaatcgctc atactcctct tgtgtcactt ccatcattgg aaatgtccac atattcgcca
    41641 gcaatttttg gctatctctt tcttcaaaat aatacgctcc agaatgattt tgaagagctg
    41701 cactgatata ataaacgtct tttggctttg ctttttttgt ttttacagga aaactcgttt
    41761 ggattcctcg tttgttagct aaacaaaagg cttggatcgg acaagtctca cactttggag
    41821 aagttggtgt acagatagct gaacctagat ccatcattgc ttggttgaat tcacctggat
    41881 gcttttcatc aatgattttc cgcatcgctt catcaaagat tttcctgcta gaagcttttg
    41941 cgatgtctgc ttcaatgcaa aacaatctgc tgactactcg catcacgttg ccgtcaactg
    42001 caggttctgg aagtccaaat gcgatacttg caatcgcgcc tgtcgtatat ggtcctattc
    42061 ccttcaatga gctaatttct tcaggcgttt gcggcatttc cccatcaaat tctgacatga
    42121 tctgtttagc agcagcttgg atgttccggg ctcttgagta ataaccaagg ccctcccatg
    42181 cttttaaaag cttttcttct ggagcatttg ctagctcttc aattgtagga aaccattcca
    42241 tgaaacgata aaaataatcg atcactgtgt ctactctggt ttgctgaagc atgatctcag
    42301 agatccagat acgataagga tcacgattat agcgccaagg caggtttctt ttttcttgtt
    42361 cataccattg aatgaactga tcttgaaatt cttttgtttc tttatctgtc catttttccc
    42421 attctttatt cactttcctc ttccttttcc gtaatgaatc gctggatcat atccaaatca
    42481 aatccttttt gatataagct ttgctttact tttagatttc tttttttagg ttcaaacctt
    42541 aaatttcttc gccatagttt atctccttgt ttgactaaat aatcatattc tatttcttga
    42601 tctgcttctt gcggaagatc agctatcgct tgttggatca cttcttgaga aaagcctttc
    42661 gtcatcaatg tttgttggat ttttctcaat aattcttttt ggctttttcc gtgatttttt
    42721 ccaaacgctt tttcggctgt ctgatgtgca ttttgaactt ggtcttcaaa tgtatattgg
    42781 ctgagcgctt gttcaatgat ttcaggtttc aaaccttttt gctgcatctg ctgcgctaat
    42841 ttctttggtc ctttgtcact taagcgcata ttcgtgcgca cataactttc cccatagacc
    42901 aaatcatcga caaggtccaa ttcttttaag cgggctacga ttttatttcg atcttcttga
    42961 aggatttcct tttcttttaa gtatgttcgg atttcttttt ccgatcgcaa ctgataactt
    43021 aagtaattca ttgctaggtg aaaaccgaaa tcagctccgc tactcttctt gatctcttgg
    43081 atagtttctt cgtctaattc ccgtcctttt aataatcgat agcgtactaa tacatcttca
    43141 gatacttgta aagcttctcc ttcagataaa tctacgcgat agaaagggcc tttgccttta
    43201 ctgattctcg taacggttaa cataaacatc ctcctcgaac atatattctc tatcatacca
    43261 cagaaaatcc ccgtaatcag gtattatatg ttagaataaa ccacagaaaa aagaaaaagg
    43321 gagatactta tggcagaaac aattgtcaaa actggacaaa cggttccttt gaaaatcaag
    43381 cgtttaggca taaatggtga aggaatcggt tatttcaaac ggttgatcat atttgttcca
    43441 tatgcactac caaaagaaga agtactagtg aaaatcacga aagcaactcc tcgctatgca
    43501 gaaggagaat taataaaagt caaaaaaaca agcaaagatc gcgtagtggc accatgtcct
    43561 gtttactatg aatgcggtgg ctgtcaatta caacacttag cttatcaagc tcaattggat
    43621 tttaaaaagg atctgctttt gcaagcattg gaaaaattca aaccagcagg ctttcgatct
    43681 tatcaacttt tgccgacgat cgggatggat gagccttggc attatagaaa caaagcacaa
    43741 tttcagttac gaaaaaataa gcagactcaa aaaattgaag ctggtttata cgaagcaaac
    43801 tctcatcagt tagtccctat aacagactgc ttggttcaag aacctcgaac acaaaaagta
    43861 atgaatactg ttgttcaact attgaataaa tttgatgcac ccatctatga tgaacggaca
    43921 aacagtggaa tcttccgcac aatcatggtt agaatcggtg ttaaaactgg ggagttacaa
    43981 gttgttttta ttactcgcag taaaaaattc ccgcaaaaaa acgcaatgat ccgtgagatc
    44041 aatgaacgac tgcccgaagt tgtttcaatc atgcaaaatg tccaggcaca aaaaacgtct
    44101 ctcgtgatgg gggatgaaac gatccactta tggggaaaag aagccattga agaacaaatc
    44161 aatgaagtga ctttcgatct ttctcctcgt gccttctttc aactcaatcc tcagcagacc
    44221 gaattgcttt atggcgaagg aatcaaagca ttagatgtcc agcctaatga aacgatcgtg
    44281 gatgcttatt gcggagttgg gacgatcggc ttaagtgtag caaaacaagc caaagaagta
    44341 cggggaatgg ataccgttcc tcaagcaatc gctgatgcaa aaaaaaatgc ggaaagatta
    44401 ggatatcaca acactcgata tgaagtcggg acagcagagc aagttctgcc taaatggttg
    44461 aatgaaggtt ttcagcctga tggtatcatc gtagatccac cacgtacggg tttggataac
    44521 gcattgatcc aatcattatt gaaataccct ccaaaaaaac ttgtttatat ctcctgtaat
    44581 gtttctacac ttgccagaga tctggttaat ttaagtaaaa agttcaagat tgaatattta
    44641 cagtccgtcg acatgtttcc tcagactgca cgttgtgaag ttgtcgtgaa gatgacgaga
    44701 ctcgctgact aaatgaaaga ggttgtgaaa aagtctgccc tgtatcaagt aataagaaca
    44761 gccaaacaaa aatagctctt catgttttat gaatactgta cttgtgaccg aagagttaac
    44821 aggaggacac tatttattta aaaaaagggt tgtgacatag tttttgtcac agcccttttt
    44881 gattattatt ggatattcac gtctatcact tgataaaatg catttgtcgt atcgctgata
    44941 ttccatactg ctaaaatcac attatatcct tttcgatcct gcggaagtgt gatcgtttgg
    45001 ttgactgttt ttggtggaac agttgctttg tcgtctattt ttgtgatcaa ttcaaaatca
    45061 ctaaatttca aaggttgatt aggattccaa gttggtttgg taatgtagta atcccaagta
    45121 cttgtccgat gttgtgctgt taaattccaa gtaatattta atgttcctgg attaaccatg
    45181 tttttatgcc atctgttaga tgtctgttca tctaaaggct caaagccgct gactcctgca
    45241 ctagcaattt ttccatcaat gaatgtattt ttggtagctt cgatactttg cggttcccat
    45301 tgtgctcttc cgacattttg atttaagttt cctgctgctg atgttcctag gtatgcacgg
    45361 cttcctggag aagtaatata accatgcgca aaacctggaa tgctaaaacc gaacaaccct
    45421 aaactaacta acccaataaa caataacgta ctaatctttt tcatgtagaa acctccttca
    45481 tttgataacc acattgtaaa cgctttattg tattaacaca aacattatgc ttttataatt
    45541 ttatgttgaa gtaaaaaagg tgaaaaaagt aagatgcaga ttataacaga agtagacgag
    45601 aaaagtacaa atagaaaaca tgagaatcaa atcatatgat ctttttcaaa aacatcattc
    45661 atataaacaa atgttcaact ttttaataac aacaattatc aatttttttc ttacttcaca
    45721 aactaaatac aggtcttgct gtgagccttc atggtaaact aatattatag aaaggagtta
    45781 gtaaaatgaa gatgataaaa gatattcgtt tttgggtttg tgttatagga attgtcatat
    45841 taggcttttt atcagggttg cttagcggaa atcccggaaa atattactat tctttgcaac
    45901 ttccaccatt tgcaccacct agctggatat ttgggccgat gtggacctta ctgtatatat
    45961 tgatgggtat ttctctttat ttgttactta atcacaacaa caaaaaacag cgaaacaatc
    46021 ttgtcggtct ttttgtgatt cagttcattt ttaattttat atggtctgct ctatttttta
    46081 atttaagaaa tattttcatt gcagcaatcg atattacact tttagttatt ttcttgtcag
    46141 tgcttatgta tcagttgtgg ctgcatcatc gcctggcaat gtggctcatg attccttatt
    46201 atttatgggt actattcgca actctattga attattcaat ttatttttta aactaagcgc
    46261 taaaaagaga cgtcctgtaa tttaacacat agaaaaagtg ccacctaagt tagatttttt
    46321 gtctaattta ggtggcactc tttattaacc aaactatttt tttctagtac ccacttgttg
    46381 ttccatactc attattctgg tcataaccat aaccattttg ttcctgtcca gcgtaaggat
    46441 cataactttg agtatcttga cttggtgtat agtactgact tgtatcttct gtttgctgat
    46501 aataggtatt cggatcttgg tactgatcat atgtgttttc tgaataggaa gaataatcgg
    46561 tgtacccttc actattcgat ccatcaccgt ttgtcgaatc gccatcttcc gaatcatcaa
    46621 agaacatcat tgaagcattc tcatttttca aattaggtaa tgtatcgctt gtttttatat
    46681 ttaattgttt cttcagttca ttttggatcg aaagaagatc attttttcct aaaatttgat
    46741 agtagatatc attgatcatt tgtccttcgc cttgcaactg gtcttgtttg attgtttcaa
    46801 acgccggggt gtagttcgtc gctacatcaa gcatgtcatc ccaatctaag tccgtcgtca
    46861 cattgttctc aactgctttt aaaatttttc tataattgct tacgccatct aaacttaaaa
    46921 ctttattgac gattttcgtc actacttccc gctgacgacg ttgtcgaccg atatcgcctt
    46981 ctggatcttc gtgtcgcatt cgagaatagg ctaaaccttt ttctccattc aatgtttgtt
    47041 cacctactgg tacatggaca ccatccaaag taaagtcaat tttattattc actttgatgc
    47101 caccgaccgc attgatcaaa tcttccatgc catccaaatt gatcgttaca taatgatcaa
    47161 taggaatatc gagcagttgc tcaattgaat ccatggccat ttcgacacca ccaaatgcgt
    47221 aggcatgatt taatttatct accgttccat aacctacgat attcgtataa atatctcggt
    47281 ccaaactgat gatcgttgat tttttttgtt tcggattaac tgttactacc atcatcgtat
    47341 cagaacgtcc ttgttccgtt cttcctaatc caccggtatc taaacctaat agcaaaaccg
    47401 aaaaaggttc tttgtcatca atgcttactc tctcagaacg tttggaggat attcgattag
    47461 agtttttaga aattttgttt actgtttggc tcgcttctcc cataaatctg attccgtatg
    47521 ctgataatcc ggcaatcagc aaaacgaata cccctaacaa ggttaataga actttttgcc
    47581 atcgcttcat aatacacctc tgtttcacat tttctaaaat attgtctcat ataactgttc
    47641 aatcagcaaa ttcacttttt aatcataaga aaactttaaa aaacattttt gtgtaacgat
    47701 tattattttt taaaatttct caaaattctt aactatcata ccataccgtg aaaaagatcg
    47761 aaagaccgaa tacacgcagt tcgcaatcgt tttatctttt tttatgtatt ttttccagaa
    47821 aaagcgaaca acaaggtatt ttccaaataa tcgtgcagta aaatgatcgc acataccttt
    47881 cccatctttt taacagtctt tgcctaccgt tcagattatc attcgatttc acgacaattt
    47941 cttcctatga ctggtccttt tgttaaaccc atcttctatt cgttttattt ccagctcact
    48001 gcatggctct taaaatgact cgaactagtg attgcattac catcatcttt taatggatag
    48061 atatgctcct cttcaaagta aaacgatttt cttttaaagt aatagaattg acatggtaat
    48121 gagtatgtat actagtggtt tcacaaatgg tcttttattc aacatccaaa aactgaaatt
    48181 tctttaaaat ccattactaa cgaagaaaat gttccttgct tgataattag ttaggacatg
    48241 tcaagtgaac aaatgcattt acttagccaa aaaatctaaa aacttcataa atagacaaaa
    48301 agacacgact ctctaagaag tcgtgtcttt attcaacaaa ttattataat ttagtcactt
    48361 cagcagcttg aggtccgcgt gcaccttcaa caatcgtgaa ttctacttct tgaccttctt
    48421 ctaggctctt gaagccgtct ccttgaattg ctgagaaatg aacaaatacg tcatctccgc
    48481 cgtctactgt aataaaccca aatccttttt cattgttgaa ccatttaacc gttccgtgtt
    48541 ccataaatgt atatcctcca aaaaagttct tgcaagtaac cttgcaagaa cattataccc
    48601 aatttagaaa acgctagcaa gctttcgctc ttttattttc caaattattt ttaagactga
    48661 tatgacggag gaaatggtta ttttgctgct tcgaaacgtt tgtttacttc atcccaatta
    48721 ataacattcc agaatgctgc aatataatct ggtcggacat ttttatattt caaataataa
    48781 gcatgttccc aaacgtccaa acctagaatt ggtgtctttc cttccatcaa tggagaatct
    48841 tgatttgcag tagaggtaat agctaatttt ccattttcca ttacaagcca agcccatcca
    48901 gaaccaaatc gtccagcggc tgcttttttg aattcttctt taaaagaaga aaaatcacca
    48961 aaagcttcat taatcgcttc ttttatttct cctgtaggtt cgccaccagc atttggtgcc
    49021 atgatttccc agaaaaatga atggttagca tgtccgccac cattgttacg tacagctgtc
    49081 ttgatatctg ttggaatagc gtccatatca gataataatt cttctattgt tttttcgcct
    49141 aattctgggt atttctcaat tgctgaattt aaattcgtca cataagtatt gtgatgctta
    49201 tcatgatgca gatgcatcgt ttcttcgtca atataaggtt ccaatgcgtc atatgcataa
    49261 ggtagatctg gtaatgtgta agtcataaaa aaattcctcc tcaatgtttt cttaataatg
    49321 tctacattac aaagagtaac aaagagaagg aaattcttca attgttatgc ctagtcgtct
    49381 ttttcacttt gacctacttc ttcttcaaaa acctcagttt ctttaaaaat aaacaacttg
    49441 ctgaaaatat agttcgcaag gataacaata atttgagtga tgattttcgc cacatactca
    49501 ttgctgttca taacattgat caacaatacc attgccccca tgtccaatcc gtaagaaagg
    49561 atacggtaga agaagaactt accgcattca ataagtgcat gtgtaaaatt cggtgatttt
    49621 gaatggaata cccaaagttt gttcgttaca aaagcaaaca atacagaaca aaaccacgaa
    49681 atagaattgg ataaggccat acttaaatca aaatattggc gtgcgagagc aaaactaaca
    49741 aaatttacaa tcgtagccaa accaccaaaa aagagataga ctagtatctc ccaatatcct
    49801 tttgcttcta aatatccttt taactgtcga tactgcttca tgagccaacc taccttatta
    49861 aaaattctta tttatcatac tctatatttc aataactttc atctttattt aaaaaaatta
    49921 attttttttg atcctttgcc tttgtctctg cttggatcgt cacatgtgta ataccatatt
    49981 ttaattttaa taaagaaatt atacgaggat atatcttttc aatctcgctt agtagctgat
    50041 cttcaaaatc aatatgtccg tcgaaaataa ttatcttttc gctatactgc caaatatgga
    50101 catgatgaac atcctttacc ccatcgattg cttcaatttc ttgttccatt ttttcatagt
    50161 cgatagcagg tgcactttgt atcaaaatag cggcagcttt tttgatcacc attatcgctt
    50221 ctatcaatat atatatcgaa atgatcagtg taataactgg atcgatccag tagatatcga
    50281 aaaaacggat caaaattgct ccgataatca cacttaccga agacagtgta tcacttaaca
    50341 aatgcaaata actagatttt atattcaaac tttcatctgc ttcttgtcgt aataataata
    50401 ctgagaacaa attcgcgagc aatccaataa ctgctactgt tagcatcaaa tgactattta
    50461 tcttttctgg tgaagtgaac cgcttgaatg cttcaacggt taaaaacaag gataatatga
    50521 tcaatatgaa tgagttgatg aaagcactca atatttctaa acgctggtag ccatacgtac
    50581 gttttttatt tgcttctttt cgggccattt tttgtgcccc gtaagaaaaa ataattgcca
    50641 atgtatcact aaggttatgg aaagcatctg aaacaagaga caaactccct gacataatcc
    50701 ctccaataaa ttctgataaa gtgatcaccg cattcaaaac cactactcca aatagttttt
    50761 ttgatgatct ctgtggctgt gtaggcacta ttccttcctc cattttattt atattggata
    50821 gtctttagac aagaataaca tttttttgat atttcaccaa tcattcagct gtttccttaa
    50881 agcacttgta tttcacttga tacttcgcta gaattgcaag tgatgacact actagatgag
    50941 gagtacttat gacaacaaaa caattaatta tcagttcctt tatacgattc aaagacctaa
    51001 aggaggcgag aaatgtccca ttttggaaag ccattgtcta tcttttagtt ttgagtataa
    51061 ttatggcttt gccaatctct tttcaagttt ttcaagtctt aaacaacatt caattggatg
    51121 ggcaaaagat tgctactcgc attcctgatt ttacaatcca aaacgggcag cttcaaaccg
    51181 aagaaaaaga aggattcatt taccaaacaa actccattat cttcacattt gatccagagg
    51241 gaaaacgaac agaacaggac atctctactg atttgatggg gaattttgtt agtgtcggga
    51301 tgttaaaaaa caaacttatc atagctcttc ctaatacagg cacgacttct gctttgttga
    51361 acaataacca attagaactt ccctacacca atgaatcttt aaaaaactta acaggtaagc
    51421 agctccgttc ttttttaagt gaagcatcta taccactttg gataaaagtc ctgacattta
    51481 tattttctat ttatcctagt tttctgaatc tgctgatcac tttgctattt accaacattg
    51541 ctgcttttct ctatgcacgc tttcgactaa caaaagctac ttttcttgat tgtttaaaaa
    51601 cattgatcta ttcaatttca ttgcctacta taattgcaac aatcttgatg gtctttcttc
    51661 cttcttttga cactagcgcc ttcattgctt ttgcaggaat ctttattttt gctcaagctg
    51721 tcaaaggatg ggcaaaaata tcgatcaatt aagaaataaa gacaactcgt tatttctact
    51781 tcaatagacc cttttagagg ttgtgacatt tttttgtcac agcccctttt ttatttgaaa
    51841 aatatttctt tctcaaaaaa caagcaaggc gcttcaaagt tcttcttgta tgcgctacac
    51901 ttagagtaaa gaaaggcggg aaattaacta tgtcagaaag aatcatttat gcagatcgtc
    51961 catttcgtga tgaatttatc gaagaaatcc atactatagc gcctggttat atctttaaaa
    52021 cagaattaca accagaggat ctacaaaatg tagagatcag tttgggctgg aactcagact
    52081 accaagaaaa actattagcc tcttctacct tgaaatgggt ccaatctatc tcagctggtg
    52141 ttgatcagct accccttgag actttttcaa agaaacatat tttactttca aatggtagtg
    52201 gcatccacag tgaatcgatt acggagcatg tcttaggaat catccttggg tattctcgtg
    52261 gtctttttca agcacaaaag gcacagagtg acatgaaatg gttaggttca tcggtccatt
    52321 accaatctat ccaagggaaa aaaatactaa tcattggaac tggccatatt ggaaaaatga
    52381 ttgcaaaaaa atgcaaagca ttagacatga actgctatgg aatcaataca tccggtcatc
    52441 cagcagaagg aatggaaaag actttttctt taaatcaact aaaggaagtt cttcctgaag
    52501 tagatttcgt agtcaatatc ttacctctaa cggaggaaac aactgggctc tttgatcagc
    52561 atatgtttga acactttgat ccaaaatctg tattcatcaa tgttggccgt ggtgcttctg
    52621 ttaagacaca agatctggtg caggctttaa ataaccagca actttccttt gcagcattag
    52681 acgtttttga ggaagagcct cttccacaag atcatcctct ttggaaaatg gacaatgtac
    52741 tgattacttc ccacattgca ggtttgacac ctgattttca aaagaaatta atggctattt
    52801 ttttaaccaa tctgaaaagc tactttgcca cccatgagct tcaaaccaat caagtaaaat
    52861 tgtctgcagg atattaatag ctgaaaacaa tattttcaaa agaaaaaaga gaaggtgaca
    52921 aaaattgtgt caccctctct ttttttattg ttttttaaag tgataggttg gctcctccag
    52981 gttgggatca taatcaacaa gtaaatcata tcctttaaag aaccattcat ctgcttcctc
    53041 gataaaaaaa agtgtcccat caatttccac tttctttaca ggatgttctg gctgttcaac
    53101 tgacattcca atcgaaaaac catcatgaac ctctgttttg ccgtagactt ttccaaaaaa
    53161 acgtattccg taagtttctg gcagatcaat ttctgagtca aaccactttt gtgcttttgg
    53221 cgttaccgtt aatttcatcc caacaaccta ctttctcttt tctttctatt gattcatctt
    53281 atcgtctaga atatccacat cgcctgtctc tccaataacc agtagattat cattttcacg
    53341 aacatattca tctgctgcag gagaagcgat aaccgtttga tctactcttc gtatggcgac
    53401 tactgttaag tcaaaacgtt gcctgaaatt taattcagct aatgttttgt tgaaaaattt
    53461 aggattggag actcggattt ctgctaaaga atatttatct gacaactcta ggtaatctaa
    53521 aatattcttt gacactaaat tatgcgcaat ccttattccc atgtctcgct cgggatggac
    53581 gacgcgatca gctccgatct tttcaagtac tctggcatga tactcatttt gggcttttgc
    53641 taaaatattt ggtacgccca tttcctttac catcagagta actaagatac tggcttgaat
    53701 atcttctcca atagcgacaa ttacatgatc gaaatttctt atgcctaatg atcgaagtgt
    53761 catttcatcc tgtgcatttg ccacaacagc atgagtggct atattcatat attcattgac
    53821 ccgatcttca ttactatcaa tagccagtac ttcttgacca gcttcgatca gtgttcggca
    53881 gatacttccg ccaaatcgtc caagacctac aattgcaaaa ttttgtttca ccgttttcct
    53941 cctttagtat cttcttttct cagtataaca aagcctttac aaaaacaaaa gcaagcatca
    54001 ttattgtaaa aaagccaaga aaaataatag ttattttctc agcttttgat tatcctcttt
    54061 atcatcgttt ttatttcacc aaaccatgtt tgaatgcata gatagcggct tgtgtacggt
    54121 cttccacttc tagcttagcc aatatattgg aaacatgtgt ttttactgtt ttcagtgtaa
    54181 taaacaattc gtccgctatt tcctgattac tttttccttc agaaatcagc attaaaattt
    54241 cattttcccg attcgttagt tcttcatgta atacaggctc atttcgccga ctcatttttt
    54301 ccatcatttt tgttgtcact tctggttcta atactcgctc gccacgttgc gttgccctta
    54361 tagcatcagc aatttcatgt gcggtagagg tcttcaacaa ataccctgct gcacctgctt
    54421 caatggcagg ataaactttt tcgtcatcaa taaaactggt tacgataatg attttagctt
    54481 ctggccaatc ttttaagatt gcttttgttg attcgatacc atccatttct tccatgacta
    54541 agtccattaa aatgacgtcc ggtcgaagtg tcatcgcctt ctcatagcct tgtcgtccat
    54601 tttcagcttc tccaattact tcaatgtctt cttgaataga taaataaaaa gagacgccta
    54661 agcgcaccat ttcatggtca tctactaata aaacttttat catccttatc tatgcctcct
    54721 tcatcaaagg gaccttgatt tctacacttg taccttgacc tttaaaacta atgattttta
    54781 ctgttccacc aataccagct actcgttctt tgatattgtt caatccataa cttcccgttt
    54841 tcgtttcatt catattaaac cctgttccgt cgtcaataat acgtaacaaa agattattgt
    54901 ctattttgtg caaatatacc tctaattcat tggctttagc atgtcttaat gtatttgata
    54961 acaattcttg aacgattcgg aacaagtgat cctcaatgga actagatagt tttacatctt
    55021 ctacatccca tttcagcgaa atctggattt tattttgcaa ttccttcaat aactgttcga
    55081 taccttgctt taaacttttc tcttctaaat tgactggacg tagatgaaga agcagcgcac
    55141 gcatctcaga ctgggaagcg ttgatgatct ctgctaccat tttcaactgc ttgcgaaaca
    55201 tttctggtgt ctcgcttttt tctgcttgct ccgtcaatgc cgacatcatc atcattgctg
    55261 caaacaattg ttgcgaaact gaatcatgca gctcacgggc taatcgatgt ctttctaatt
    55321 ctaaaatttc ttctttggtt tgtccatcta catattgggg acggctcgtt acaatttgta
    55381 attcactaga tacttcaatc attttttctt ttatcttagt gatttcctta tcaatatctt
    55441 tgatgtataa atcgtccgat gcacttggga tcggaagaag caacaatttg gattcataat
    55501 tgccagaaga aagtgcacgc agcttttctt cgattttccc gtattttgtc ttttgaataa
    55561 gtgataataa tagaaagaca attaatccta cacctaagga aatggctaac aaatggaaga
    55621 taagcggaac atataataaa cgtgcacgca gtaattctcc ccaccaatga ctttgattgc
    55681 tggcataaaa ataagtgaaa agtgaaaata gaataataag gaaagccgca atccccgaat
    55741 aaacagctag catcgctctg gatatttttc ccatcatatt cgtatcacct cgacatctcc
    55801 aatcaaggta ttagtaataa tcttcaatct acgagggttt tcatcataat cactgctgta
    55861 gattttgatt tgttcatttt tcaaagaaaa ttgctcttct tcaaacaaga catttcctac
    55921 taatgtcgca tgctctaatc ggatggctac gcccaaaggt actaagatcc gtgttctgcc
    55981 tatccctttt cttacaatca caatattatc atcttttggc aaaagcgtat tgcccaaatc
    56041 tatgatagta tcaccagaaa tgacggcgat gttgatatcg tcccattcat agacgtcgtt
    56101 tccaatacgt tggttaccga ataattgctg tcttttccgc tcattattat gtgtttttaa
    56161 ttgctctgtt tggatcatca tgatctgttt ctttcgccaa aaagcatttt tggttaaatc
    56221 tatccctgaa atctctacac ctttcagacc aataaataaa acggcaaata cagccatcat
    56281 ccataaagca ggactgttga ctaagctaaa aaaaatgacc aaacttccta atatcaattg
    56341 aaaattttga aatttagtac gaggatgttt gcgcatagct agatatatat tgaaaatacc
    56401 gaatatcact aaaagcaaaa gtccagtatt gtttacgatt tgccaaacag caaataacag
    56461 cagtagtgct tcaactacca caaaaaaacg ccaagaacta ttcatcgctc tttctccctc
    56521 ctgacacatt ctcatttcat catacctatt tttttaactg ttggctatag gactttagat
    56581 gtaagatcgt ttgttgaaat ctaaaataca caaagagaaa aagatctaga gtgtatcatc
    56641 agtaagatga actctctaga tctttcagtc agactacgct tgttctactt tgacgatttt
    56701 aactaacata tcgccacctg gagtagcaat agttacttca tcatttttac gtttgccaat
    56761 caatgcttgc gcaataggag aatcattgga aattttgcca gaaaacggat ctgcttcagc
    56821 gcttccgaca atcgtgtact cttcttcttc tccatctggt agttcgatga atgtaactgt
    56881 tttaccaatt gatacctcat ctgcatctac accgtcgtta tcgatgattt gagcaaaacg
    56941 aatcatattt tcaattgttg tgattcttcc ttcaacaaat gcttgttcat ctttcgctga
    57001 ttcatattca gagttttcgg aaagatctcc gaaaccgcgg gcaattttga ttcgttcaat
    57061 gatttctccg cgtttgactg tttttagttc ttctaattct ttttctaatt tttctttacc
    57121 ttctagagtc attggataaa ctttctctac catgtgtaac gtctcctttt ttcgataaaa
    57181 taccgcaaaa ggtaatcttt tgaggaatat agtccaaaaa agattaccac gcttttcttc
    57241 aaatgtaaat gtttttctaa aaatgatcaa tgtctagagc ctgtttttct aagaattatt
    57301 tacatatttt tccactaatt ccatatgttc ttcataagtt ttagcgaaat aaacatttcc
    57361 agtgctcgta tctgctacga aataataata gtcattttct gctggttcta atactgcctt
    57421 gattgcctct tcgcttggat tgtcaaaagg tccaggtcca tagccggtat tggtatacaa
    57481 attatatggt gaatctacag ctgtatcttc atacgtcact aattctttgt gttcacctaa
    57541 tgcgtataaa acagagatat ctgactgaag tggcatattt gctttgattc ggttaaagaa
    57601 gacttgtgca atgtttttac gatcattttc ttttacgcct tctttttcaa ctagagaagc
    57661 tagagttaaa acttcttgta cagtcaaatt tttctgcttg atagctgaat aatagttttg
    57721 catgaccgta ttcgtcttgt tcaccatttc aatcactaga tccttaagcg aagtactcgt
    57781 gtaataatca tatgtggctg ggaataagta accttccaaa cggtattttg tgttctcagc
    57841 tttagatgca ctttccaaca gttctgggaa tttttggtgc aactcgttaa agaaagtctc
    57901 atcattcact aaatctaaaa attctttctt gtctttacca gttaccttcg ctacccgttc
    57961 agcaatctga tcgatatcgt acccttctgg aatggcaatt ttcccatctg caacttttgt
    58021 tggctcagaa gtaccgcctt cttgcaactg tttgccaatc tcgtcaagag tcatattagg
    58081 cgctaactga taatagccag cttgaaagcc agttaaattt ttaaattttg tataataatt
    58141 gaaaacaatc ccgcttttaa taatattgtc cttctccaaa atctcaccaa tctgcttgtt
    58201 agaagagcca ctcgggatct cgacttggac taattggtca tctgatttat ctaaaggctt
    58261 caacccgcta tctacataac gatacacggt aaatccaaga aatccgccaa taatcaataa
    58321 tgtaagagca atcactaaaa tgatcttcct cacaatctta tcttcttttt tacgcagatt
    58381 tctccgcttg tcgattatat ctgctgtagc tgccttactg gcttcttttt tatctttact
    58441 tgggtgttgt ttgtttcctg acaaaacaac tcctccttac tatcaagttc gtaactttat
    58501 tcattataca tgatatttga attggcgtga atgattttat ttaaatattc tatcaaaaat
    58561 gtaagtagta aatccattac tataagatta aaataaatgt tatcaagata caagctattt
    58621 tagctttatt ctttctgtaa aaaagaaagg agactaaata aactattatg aaaaaaggaa
    58681 aacatgctaa aaaaagaaaa tattcatttt taatgatcgt tgtcgtgttg tttagcctta
    58741 gtgcgttctc tacaggaact attcttggat ggcaatttta caataatgaa cactctcaga
    58801 tagttgccca tgctcaatca gctcaaaaaa agttgatact gactaccaat gaacaacagc
    58861 tcgttgaaaa aatcgatcaa ctattaagaa aaaatgatta tattggctca atttacgtaa
    58921 agaaaaataa tcgcatcatc atggaaaaag gctatggcta tgcgaataaa ctcacgcaac
    58981 aaccaaatga tccttctctt tattatcaga ttggttcggt tcaaaaagca ttgactactc
    59041 ttttgatttt aaaacaagtc gagcgtgggc acctttcttt agatactaag ctggctcaat
    59101 tctatccaca aattgctggc agccagcaaa ttactatccg tgacttgctg tatatgcgct
    59161 caggcttgca ccgaactgct tctccaacca taccgatgac tgatgaagaa gtcgttcaat
    59221 ttgcgattca gcacttaaaa tttacagatt atcagacctc tcattatgat tcattgaact
    59281 ttaccatatt gactggaatt ttgatcaaat taacaaatca accgtatgaa aaattattga
    59341 ccgatgatat catcgaacct ttaggattac agcatacaaa attttatgac caagtcaaaa
    59401 attcatccaa tcatgcacta tcctatcaaa tgtctaaaga ggatgattac tttaaaccac
    59461 tgacagaatc tgaaacagag atccataacg aattagggac tggtaatatc agtatgtccg
    59521 tctatgattt aaatacgctg tttacacaag ttttatctgg aaaactagtt tccaaagact
    59581 tactcttctc attatggcgt gaaaatgcga atggacatcc atatagtggt ggggtatata
    59641 gcggagataa ttatatcctg tcgcaaggaa atatcgactc ttttgataca tctgctatat
    59701 ttagcaaaga ttcacaggat gctatcatca tggaaagcaa tataaaagct gacaaaacta
    59761 tcaaactgcc tactgctgat ctaagaaacc aaatctatga cctgatggaa ggaactacta
    59821 agttggcaaa tagctgatat gatgaaaaga tagcaaatac tacttctttg aatagcattt
    59881 gcttaaaaaa agtactcgac taaacgtagg aaagagtgtg ggacaaatct aaaaatcaat
    59941 ttttgctaca gactttaatt ccaaataaac agaacagaaa gaggtgttct tctttctgtt
    60001 ctgtccaaat tattctaaga tttctcttta ccaacattat ttgacaaagg gcctattaaa
    60061 tctaaaatag tatctttaga ttgctaaaat atgtgctagc aaatcattca tggcttgttc
    60121 ttatttttaa ttttatgcaa taaaaaagaa gaacaattag cgtgattata gaaataaata
    60181 atgagatttt agaaaaaaat gtgtatgaat acctgattgt tactttattt attccacttt
    60241 cactttttac tgtaacaaaa ggacctcctt gttttagtac tgtagcattt tttgaattaa
    60301 cagtaaccgt taatccttta taccggaata caggtaaaac tattgttttg ccttttgaag
    60361 atttaaacgt aaatgtaatt tcatctttat ttggagaaaa gctactataa ataacttgac
    60421 catcttctgt aacttgatgg tttttcaaaa gcaattgatc ttttttatag cctataggta
    60481 cataatcaaa attctcaaat tcttcaagtt tattttccat ttgttcatta gaataagttc
    60541 cttgaaaatt catttctttc accatgttaa ctactgatga ataatttaaa attgaaatag
    60601 ctaatattaa taatagtata aaatttcttc tccttgtata agaaaatttt tccaactgtg
    60661 gagaaataaa tagagatact gaaaaagata tgaacaatgt tgaaaatatc ataaaacgcc
    60721 aaggagcttg aataatattt aaaggagtat tttgtaaggc aaaccatgga aatatttttg
    60781 tacaaagtag aatagatatt atacccatta tataagtgat tttagataag attcctaatt
    60841 ttttaaagtt aaatgttagt ataattaaac aaataagcaa agttaagcca ataccaaatg
    60901 atagtaattc tgaatctata cttccaatca aaaactcttt acccagataa attgctcttt
    60961 tttgtaatat atccacataa ggtctattca gatcttgata caatgtctgc tcaatcatag
    61021 gacctataaa cgctagtgaa agaagtaaag taactatagc agcttttatt aatttaataa
    61081 ttaagaagat ttctattttc tttttccgat aaaattgaat aattaaagca attataatca
    61141 ttaccatagt catagctaca gaaagaacat gagtgtaaat taataaagtc atgctaatcg
    61201 ccaacataac ccaagattct ttttttgagt cgtaaagctt tataaacccg agtaaaataa
    61261 gaggaagtat tgacattgcg agtaattccc ccattgcccc tcgaagaaat atttctacac
    61321 tcctaaaaga agatgttgta tatataatag cgaaaaagga gctagtaaca tgttttttgg
    61381 taatttcata cattacataa tgacatataa atagagtaat gagcgtaaca atataaagaa
    61441 aaaggttata gcctattgct aaattagtaa acttgatcaa taaaaataaa ggatatagag
    61501 ttaaccatgg gtaaaaatta tttacttgca tgccatatga tctaaacgtt tcaaaattaa
    61561 taggggagct aaaaatagat tctaaactta acgcacgatt aatgtgaaat gccgtatcat
    61621 aaaagccaaa tatttccatg tttttaaatg ctggaaataa atataataaa ctaacaaatg
    61681 cataaactat aaatattttt acagaaaaaa tttttttcaa attcatatac cacctcatgt
    61741 ttttttatat tacatatagt atcatttatt ttttttaaac actagattag tca
//
LOCUS       DADQDV010000009        59637 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.009, whole genome shotgun sequence.
ACCESSION   DADQDV010000009 DADQDV010000000
VERSION     DADQDV010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 59637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59637
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.009"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(451..1761)
                     /locus_tag="J8S10_000593"
     CDS             complement(451..1761)
                     /locus_tag="J8S10_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HAZ9629204.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1773..3191)
                     /locus_tag="J8S10_000594"
     CDS             complement(1773..3191)
                     /locus_tag="J8S10_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAZ9629205.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3431..4999)
                     /locus_tag="J8S10_000595"
     CDS             complement(3431..4999)
                     /locus_tag="J8S10_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HAZ9629206.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(5003..5413)
                     /locus_tag="J8S10_000596"
     CDS             complement(5003..5413)
                     /locus_tag="J8S10_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HAZ9629207.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(5410..6333)
                     /locus_tag="J8S10_000597"
     CDS             complement(5410..6333)
                     /locus_tag="J8S10_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HAZ9629208.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6330..7208)
                     /locus_tag="J8S10_000598"
     CDS             complement(6330..7208)
                     /locus_tag="J8S10_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HAZ9629209.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(7195..8532)
                     /locus_tag="J8S10_000599"
     CDS             complement(7195..8532)
                     /locus_tag="J8S10_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HAZ9629210.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8535..9638)
                     /locus_tag="J8S10_000600"
     CDS             complement(8535..9638)
                     /locus_tag="J8S10_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 88"
                     /protein_id="HAZ9629211.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9712..11220)
                     /locus_tag="J8S10_000601"
     CDS             complement(9712..11220)
                     /locus_tag="J8S10_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAZ9629212.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(11186..11878)
                     /locus_tag="J8S10_000602"
     CDS             complement(11186..11878)
                     /locus_tag="J8S10_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAZ9629213.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11900..12874)
                     /locus_tag="J8S10_000603"
     CDS             complement(11900..12874)
                     /locus_tag="J8S10_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAZ9629214.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            13174..14046
                     /locus_tag="J8S10_000604"
     CDS             13174..14046
                     /locus_tag="J8S10_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAZ9629215.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14504..16702)
                     /locus_tag="J8S10_000605"
     CDS             complement(14504..16702)
                     /locus_tag="J8S10_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAZ9629216.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEVEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16934..17926
                     /locus_tag="J8S10_000606"
     CDS             16934..17926
                     /locus_tag="J8S10_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAZ9629217.1"
                     /translation="MVTIKDIAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17986..19407
                     /locus_tag="J8S10_000607"
     CDS             17986..19407
                     /locus_tag="J8S10_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HAZ9629218.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSFPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19400..20899
                     /locus_tag="J8S10_000608"
     CDS             19400..20899
                     /locus_tag="J8S10_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009224330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HAZ9629219.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20938..22332
                     /gene="uxaC"
                     /locus_tag="J8S10_000609"
     CDS             20938..22332
                     /gene="uxaC"
                     /locus_tag="J8S10_000609"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HAZ9629220.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            22491..23174
                     /locus_tag="J8S10_000610"
     CDS             22491..23174
                     /locus_tag="J8S10_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HAZ9629221.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            23176..24012
                     /locus_tag="J8S10_000611"
     CDS             23176..24012
                     /locus_tag="J8S10_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAZ9629222.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            24023..25777
                     /locus_tag="J8S10_000612"
     CDS             24023..25777
                     /locus_tag="J8S10_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9629223.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(26053..26394)
                     /locus_tag="J8S10_000613"
     CDS             complement(26053..26394)
                     /locus_tag="J8S10_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HAZ9629224.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(26462..28633)
                     /locus_tag="J8S10_000614"
     CDS             complement(26462..28633)
                     /locus_tag="J8S10_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HAZ9629225.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            28844..29701
                     /locus_tag="J8S10_000615"
     CDS             28844..29701
                     /locus_tag="J8S10_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAZ9629226.1"
                     /translation="MKITITLPMNHPETTIRDLLEKEWLVPRKVRHFLRIRKNVWINQ
                     QPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDEHLIIVDKPAGMKTH
                     PNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKNPFVLPILGRMLEQK
                     MIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSALTHVTVNKVLSEQT
                     QVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHALELHMIHPFTQEKIV
                     GKALPGLWE"
     gene            complement(29772..30629)
                     /locus_tag="J8S10_000616"
     CDS             complement(29772..30629)
                     /locus_tag="J8S10_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAZ9629227.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(30614..33316)
                     /locus_tag="J8S10_000617"
     CDS             complement(30614..33316)
                     /locus_tag="J8S10_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HAZ9629228.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            complement(33329..34618)
                     /locus_tag="J8S10_000618"
     CDS             complement(33329..34618)
                     /locus_tag="J8S10_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HAZ9629229.1"
                     /translation="MAYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDTCRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            34768..35814
                     /locus_tag="J8S10_000619"
     CDS             34768..35814
                     /locus_tag="J8S10_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAZ9629230.1"
                     /translation="MNQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            35816..37969
                     /locus_tag="J8S10_000620"
     CDS             35816..37969
                     /locus_tag="J8S10_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HAZ9629231.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDKEYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(38442..39893)
                     /locus_tag="J8S10_000621"
     CDS             complement(38442..39893)
                     /locus_tag="J8S10_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAZ9629232.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(39890..41614)
                     /locus_tag="J8S10_000622"
     CDS             complement(39890..41614)
                     /locus_tag="J8S10_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAZ9629233.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            complement(41607..42221)
                     /locus_tag="J8S10_000623"
     CDS             complement(41607..42221)
                     /locus_tag="J8S10_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAZ9629234.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            complement(42566..44023)
                     /locus_tag="J8S10_000624"
     CDS             complement(42566..44023)
                     /locus_tag="J8S10_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAZ9629235.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            complement(44064..44984)
                     /locus_tag="J8S10_000625"
     CDS             complement(44064..44984)
                     /locus_tag="J8S10_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAZ9629236.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            complement(44996..45943)
                     /locus_tag="J8S10_000626"
     CDS             complement(44996..45943)
                     /locus_tag="J8S10_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAZ9629237.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            complement(46422..47141)
                     /locus_tag="J8S10_000627"
     CDS             complement(46422..47141)
                     /locus_tag="J8S10_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HAZ9629238.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            complement(47190..48836)
                     /locus_tag="J8S10_000628"
     CDS             complement(47190..48836)
                     /locus_tag="J8S10_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAZ9629239.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYLQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            49015..49605
                     /locus_tag="J8S10_000629"
     CDS             49015..49605
                     /locus_tag="J8S10_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAZ9629240.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            49697..51202
                     /locus_tag="J8S10_000630"
     CDS             49697..51202
                     /locus_tag="J8S10_000630"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HAZ9629241.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(51286..52638)
                     /gene="celB"
                     /locus_tag="J8S10_000631"
     CDS             complement(51286..52638)
                     /gene="celB"
                     /locus_tag="J8S10_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HAZ9629242.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(52638..53156)
                     /locus_tag="J8S10_000632"
     CDS             complement(52638..53156)
                     /locus_tag="J8S10_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629243.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            complement(53172..53498)
                     /locus_tag="J8S10_000633"
     CDS             complement(53172..53498)
                     /locus_tag="J8S10_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HAZ9629244.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            complement(53511..55490)
                     /locus_tag="J8S10_000634"
     CDS             complement(53511..55490)
                     /locus_tag="J8S10_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAZ9629245.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            complement(55511..55825)
                     /locus_tag="J8S10_000635"
     CDS             complement(55511..55825)
                     /locus_tag="J8S10_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HAZ9629246.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            55993..56286
                     /locus_tag="J8S10_000636"
     CDS             55993..56286
                     /locus_tag="J8S10_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HAZ9629247.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            complement(56364..57476)
                     /locus_tag="J8S10_000637"
     CDS             complement(56364..57476)
                     /locus_tag="J8S10_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAZ9629248.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            57629..57853
                     /locus_tag="J8S10_000638"
     CDS             57629..57853
                     /locus_tag="J8S10_000638"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629249.1"
                     /translation="MNGSIKKILRSIDKNLMITEVSYETLQKKKTLIVAAVLFPAPCV
                     CRNCGSAVVDGNRKLMVVKNKKKETIVHFE"
     gene            57863..58042
                     /locus_tag="J8S10_000639"
     CDS             57863..58042
                     /locus_tag="J8S10_000639"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629250.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            58236..58406
                     /locus_tag="J8S10_000640"
     CDS             58236..58406
                     /locus_tag="J8S10_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAZ9629251.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(58830..59570)
                     /locus_tag="J8S10_000641"
     CDS             complement(58830..59570)
                     /locus_tag="J8S10_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016249807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAZ9629252.1"
                     /translation="MTKANRLTPGGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGL
                     TTGADGKLAIDGLAPGVYQLVETQAPTGYELDATPIEFEIERSQTAVVELTKENRLTP
                     GGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGLTTGADGKLAIDGLAPGAYQLVET
                     QAPTGYELDATPVTFKIEKEQEVAIFLTKENRKVADSSDIRGNNPTSSGNKHLPKTGE
                     TIISQFILSILGVLLVFISIKFRKKRNI"
BASE COUNT        17826 a        12189 c        10425 g        19197 t
ORIGIN      
        1 ttgtcttgaa ttgaatcaag acgccctaca catttggttt gtcttacttt gttcagtttt
       61 caaaggtcta cttcatcgag agtgtttccc gattcatttt tggctgccgt agcaactttt
      121 atatcatatc agagagacaa acgattgtca actctttttt aaaagttttt ttcgatttcg
      181 tttttcgaaa tctttcagca actcatttat cataacttat cgtttgttat ttgtcaagaa
      241 cttttttgaa gtttttttcg atagaatcaa gcttcgcaag tggttctttt taacgactta
      301 gttatcttat cacgtctaaa aacatgtgtc aactcttttt tggaattttc ataaaatgtt
      361 tcaatgaagc gcgacaacgt tgtttaatat atcattaaaa aaaataaagg tcaagctaaa
      421 atattattta agcttgacct tattataatt tcaacgattg tcaaaagtat tgtttgcagc
      481 tgtgttgcca gtttctatag ataaatcaca gcttttgaaa cataagtttt gtactgcttc
      541 gattcgcccg aattcttttg cagttatttg gcaatgagaa aagcagacat cttctatagg
      601 cttttcagga aatgctacta aatcaaaagc tcgggaagga agtgagtaac ctggagaaag
      661 gcatgcctgt acgtttttga tgtgtatgtc tttgactttc gtcatttgct ttgattcagg
      721 tatttcttca gccactgctt gccaactttc tggcatttga gcaaggtcat tgctattttt
      781 tctattgtat tcattatgcc agtccattat ccaagaaaaa ggaaattgta catcaatcat
      841 attcagattt tctaccctga tattttcgat cactccccct ctttcttttg aagatttcat
      901 tcgaatacca cagtctgact gaaaaaaatc gatatcgtga atatatacgt cactaactcc
      961 agcactaact tcgctaccaa tagttacacc gtatcctgaa cggattttac atctagcaac
     1021 ctcgattctt gatgattttc gattgactct tgcaccattg ccatctctgc cagacttaat
     1081 agcaatacaa tcatcaccac aggccaaatc acattcatag acacgcacat ttgttgaaga
     1141 atcaatatca atcccatctg tacttggtcc atcattgttg cggatgatta ctttttctac
     1201 taatacatcg ttagaataag tgatttgcaa gttccaaaaa cctgatttct gaaaaatcaa
     1261 atcacgaaca acaacatgtt ctgcatgata cagtaaacaa gcgcgtggac gtttaatagc
     1321 ataatccgca atccaacgaa gtcccttttg atcgtattca gctcttgtcc cgcttttttg
     1381 atcttttccc caatacagct cccaccaatg gtctccttga ccgtcgatta ttccttttcc
     1441 ttctataaga atatctttcg ccgagagaac attcaaaatc gctgctggcc atttcatttc
     1501 tacgccggct actcgtgtat cgatttctgg aaatgcttcg atatctgttc tccccttgag
     1561 gactgcacct tcttcaaaga taagatgact cttatctttt aaaaaaaggg ctccgactaa
     1621 ataaatgcct tttggaataa atacaggtaa gtgttctttc gcaccttgat cgattgcttt
     1681 ttgcagtatt attgtatcat cttgttgagt gtcgtttgtt ttaaagttca aagcattgat
     1741 aatccctttt tttgtccgca atacgtttct ccctatcttt cattgatttt tttcaattct
     1801 tcaccaataa atacagtttt tgaacgattc agtgggtaac ctactagcaa aatgattgcg
     1861 gatacaaata agcagaatgc tggtaacaag tttgccatcg tataaatcct ttcttgtact
     1921 aaaactgatt ggatggctcc acctgttgta gacgattggt aaccaatgag tgccagcata
     1981 aatccgccta ccgctcctgc acatgcttgt cctacttttc tcgcaaaaga atttactcca
     2041 tatactgttc catcttctct taagcctgtc ttatattgat gataatcaat cacgtcagta
     2101 atgaatgccc agaccatcaa attgaataaa ccagatccta aagtagcgat aaataaaaga
     2161 atcagatata cccatgcatt tgttatatga aggaaataca tcagcaagta catacatgaa
     2221 gaagcaagta acgcaaatac gcttgcttcc tttttaccaa ataattttgt cagctttgta
     2281 gcaaatggtg ctaaaactac tactgttccg taagtaaata aaagagcaac agacattgct
     2341 tgtttattat ggaagtaatc attgaataaa taagtcatat tcgtcccagc taaaatctga
     2401 ttgatcacaa tgaaaatgtc aacaatgact aaaataatca gtgctcgatt agctaacaaa
     2461 ccttttacca actgagaagc agatactttt tcgtttttga caactcttac tctttcagta
     2521 gtcaatttac aagttaacat atatgcgaca aatgctattg cagcacatcc gattgaaatc
     2581 caaaagaaat gattccctga aacgacttgt tgtccactct tgttatgggt atacattaaa
     2641 atcggaatga agaatcctgt agttgatccg ccaatcgcag aaccaatgct tcggaacgtg
     2701 gacaacgagg tgcggtcatt aggatttgag ctaattgctg ctgccattgc tccatacggg
     2761 atattgattg ttgagagaaa aatcccataa acaatgtatg aaacaaaaat ataagcaatc
     2821 ttcaccgtca ttggaagatg ttggacgaat ggcaaaaaca aaatgacagt cactaagcaa
     2881 aatggatact tcatttttct gatccaagga ataaatcggc cagtttctgt taactctgag
     2941 acatcacata atcttccaac catcacatca gcaaacgcat ccaaaattct cgaaatcaag
     3001 aataacgtac ctacgattgc ccctgaaacg ccaagaacat tcgtataata aatcatcaag
     3061 aaactattga ctaaacctaa aataaaacag ttacctagat caccgaacat gtagcctatc
     3121 ttatcggaaa tcccaaattc ctttttttct ttttttattg tatttgctgt aacagcattt
     3181 tgtgaaagca tttgaattcc tcctacctct tctagtaaac gttttcaaaa ttataactct
     3241 ttttttcttg tttttatatt cacaatgttg gctttttatt gcattatctt gacagataaa
     3301 aaacaaaaaa taatctaaaa acattgatgc ataagattga taactttttt tacataacaa
     3361 tatatacaaa caaaaaaatt cactaactag tgaaaataag ttagtgaacc tcatttatta
     3421 aagaattaaa ttacagatga tcttttccat catacttgaa aaactcaaaa tcagcataac
     3481 ttcctctttt tttatttaga tcatgcactg ctatcccgat aaaatttcca gtaaaccctc
     3541 ctgagagtat acacatgttt ttttgcggac ctactttctt ccattcttca gttgatacgt
     3601 ctttcaaatg aaactgtgct gtctctttct ttacagtgac tttcaaaaaa gtcttctttt
     3661 ctgtgagtgg aatcgtccaa tcttctattt gtgctactcc gttttctgat tctatcatac
     3721 gtaggcattt tcccttgtcc tcattccaag taacataaca ataaatataa ttggattcat
     3781 ttaagtacag taccagtcca gccatctgat taaaattatt aggcatgtat tcaaatgctg
     3841 tctccgcatc aaaagtaaaa tccgtttgcc gaatagctaa caaatgatgt tcgaaggtag
     3901 attgaagaga ttcaccggaa atcagacgta aaaaacctgg tctacatttt gtatcacacc
     3961 aatcagcatt tggcaaaatg cgtctggcat tccagttctt ctttagctct ccttcaaatg
     4021 tatccataaa ctgatgatct ttttcttgtt gtacctcttc atttgtctca atcattattt
     4081 cttccatcgg agttgtctgg ctatctttaa gtcttaacca atcgtcggac gtccaataca
     4141 cttcttgaat agcggtttct cttcccaaaa tagccgcacc gtttaatggt ctggtacaaa
     4201 gatatgtcat gtaccatctt cctgacgggg tttgtactaa gctcccatgt cctgtacatt
     4261 gcaatgtaga agcaggtttg tcactagctg tcagcatagg aaaaccagga tcaagctcgt
     4321 aaggaccagt aatattcttt gctcggcaaa ctgtaactga atgtcctctt cctgtaccgc
     4381 cttctgccgt catcaaataa taatacccgt tacgaaaata caaatgtggt gcctccgttt
     4441 tcgctaattc tgtacctgca aatattttat agatgggacc atcaagcttc ttcttctctg
     4501 catcatattc ttgtaatacg ataccgctgg atttattcgg tgtgtccaga cgataatccc
     4561 atagttcatt gacaagccat ttttttcccg tttcaagatc atggaacaaa gaaggatcaa
     4621 agccgttact atttaaataa attggttcgg accaaggacc tgtgatctca gatgcagtga
     4681 tcaaataatt gtggacatct ttaaacggac ggcctgcact tttgacatct gtgtaaacaa
     4741 gataaaacaa tccatcagca taactgattt gtggcgccca tatacttcca tttgtaggat
     4801 ttccttgcaa agatacttga gtggtcaaaa tatccgttgt atgtgaccag ttgactaaat
     4861 ttttcgactc atatactcgg attcctggaa gccattcaaa agaggagaca ataatgtaat
     4921 accgctcttt cactcttaat atattaggat ctggattgaa tcctcttaaa ataggatttt
     4981 tcactttgat agtctgcatg attcaggctc cttttctcat tcttactcga tataaactga
     5041 atgccccagc tgcgaaataa aaaaatgcaa aaggaaacgc aataaactga gtgccaatca
     5101 acaatatgaa tcctgttata aaatacaaac cagtggcagt tgttaagtat tttcctttag
     5161 cagtcaaaaa caatgctact gctaaaaaag caagtgaaat aaacaacaca acggcaaaca
     5221 gaccagtcat gtcctgtaat aatccaaatg tattttctaa agacaaagtt gaatgatcta
     5281 cagcaagcga ctgataactt tttttaaact ctgacgcaga catattactt aaagtaactg
     5341 ctaacccgcc aaagaaaatc aaagatagac tgccaccgac cattcctagc aatagttccc
     5401 attttctttt catttctgaa ccccctgctt ttctaaatgt atccattcag gtcttttgat
     5461 cgatgtttca taattgttat tacgttcaga gaatttgaca gtctgttcat ttttcttgtc
     5521 atcccaatta tcccaaccag ttgggtgaac atgcccacct atcttacacg cttcaaataa
     5581 gacatttgca tacggacgcc acggtcttcc taaatagacg tttctagtat caggttctgc
     5641 agtcaaggta cagctttcaa aacgataccc tgttttttga tttttcggcg tagatgctgc
     5701 tgtgatgtat ccaggatttt tactggctaa gctatggata tgacactgat gaaaaacggc
     5761 atctgcccca ccaaatatga aatccaccgt tccttcaatc cagcaatatt cataggtctg
     5821 acgacaatac tcaggattgg cagaagccgg tgtacaaaaa ggagtaccat ctttttgcaa
     5881 atcaggcaac ggacccgtgc ataaggtatc ctgataacca gatagtcgac agttttttaa
     5941 agatacgcga tctcctgaat tgaataaagc aacagcctgt cctacctttt ctcctggacc
     6001 tgctgtattt tcgatgtgaa gattttctaa tacgacattc gatccttcta agaaaaaagt
     6061 agcacttcgg aaagtcccta actggctacc gtcaagatac tcctgttttg caaaacgatt
     6121 accggagata actactgttc ctgctcccac aagtttaaaa ttggataatc tgctttctat
     6181 atattcatca tatcttcctt cttttactat caagaccttt ggatggctat ccggcaggcc
     6241 tgccaaataa tcgattcctt cttggatagt ttcaaaatcc gtcggggtat ctatagcatt
     6301 ctttccaatt atcagtttgt ctttcatcct cataaatgct cccttatgaa ttgtttccaa
     6361 atatttctca tttcttgtgt ttccatatga ccgcctgtta aagaaaaaga agaaaagttt
     6421 tctggactac ccattgattg atactttttg tccagccctt ttctcagctt cagtacgcct
     6481 tcgtccaagc acatcgtatc gttttttcca actaagctaa gacgagggcg cggagcgatt
     6541 ttttcttgga ttgctaacgt tgtataagct gtcaatagat ttggcacata gtaataaaac
     6601 ccatgatgat ctaggcggcg atgtagcaaa agtatttcga tgtccacctg tgccgctaga
     6661 tcaatacaaa ctttgacacg agaatccaat gctgtcaccc accagcttaa taagcctccc
     6721 atagaaagac caatcgttgc gagccgttga gtatctgtgt cttcccttgt ctccaaataa
     6781 tcgatcaagc tgatcacatc ataaatacgc attccccata acgtttttcc tgttaataaa
     6841 aattgtttga acaactcgct ttcagaaata cctccgcgtt cttcaaatcc ccaagcatca
     6901 atcgaccaaa cagcatatcc cattcctgtc agtacttctg caaaagatgg agaagctaag
     6961 taaggagcac catggatcaa ttcacttttc ccgactgaaa aatctccgcc gtgagaatgc
     7021 aggtaaagga ccggcggaaa cggtccttct ttttctggat aagcatagag ggctggtact
     7081 gtttccaatt catttaagta caattgatag tattcaagca taaaaccgtt ttgtttttct
     7141 cggtataatc gttttccact aggggtatgt ctgctagatg gagcacctaa aaaatcattc
     7201 aactgcataa gcaaagtttt tacgaacaac cagttcatcc atattttctg attgatttga
     7261 ttggaatttc tcaatactga tttctttagt attttctaat agaaatgctg gtccctcgtg
     7321 attttcaatc gacatctggt taaaggaaac cttacccgca aagccaatat aaaatccttg
     7381 tctgctcatt tcctctattc ctgtcatcat agcaggaaca ccgggaactg catcttgggc
     7441 catcgagaca tcgatattgt caaatgtgat ttcttgtatg aattgttccg ctaatccata
     7501 aataaaacct gcagaagcat ggacattcct tgccgtgata ttcgaaaaat ggatccttct
     7561 gaatgctggt gtccgttcat ctatcggata agcctttttt tcccatacat acggttcttt
     7621 ccctcgcgga ccacagaaat aataaagatt cagtataaat ggacacatca cattatccat
     7681 gactatattg gatactcgaa tatcttcaac gatcccgcct cgacctcgtc tagatttcaa
     7741 tcgtattcct cgatcagttt cttggaagat acaatttgaa atggtaatat tacgaatact
     7801 accactcatt tcacttccta atacgacacc gccatgtcca tggaccatcg tgcaatttgt
     7861 gatcgtgata ttttcgcaag cgatcctttc gtacgtatct tcagtccctg ccttgattgc
     7921 aatacagtca tctcccacgt caatatggca attactaata cgcacatttt tgcatgattc
     7981 tggatcaatt ccgtctgtat ttggtgaatc cgctgggttc aagatcgtca agttatcaaa
     8041 cgttgcatta ctgcaaagaa tcgggttgat cgtccaactt ggtgactgga tcaatttaat
     8101 atctttcaca gtaattcgat gacagttatg gaaactcatc aatttaggac gaggataagc
     8161 gagattatct ggttcatttc taaaagtatg ccaccatttt tttccatttc catctaatgt
     8221 accgaaacca gtgacagaga tgttctctac attttgagca tagatacagg aagcataaac
     8281 ttttcgatgg actccttccc aacgtgaatg aacaacagga taatcttttg gatcgtcaga
     8341 gaatttcaga accgctcctg cgcttaaatg aagttcgaca ttgcttttta aaaataaagc
     8401 tcctgttaga aattcacctg ctggaacaac tacggtcccg cctccgtcac ttgctgcagc
     8461 atcaatggct tgttgtattg cttcagtatt caattcatca attgatgcgc caaatgtcaa
     8521 aatatcatac atatttataa tgcctccact tcaatcaatg cttgcaagaa tgcaccaacg
     8581 cctttttgat cattacaaat aattggttca ctgatgtagt aagcatatga accatctcgc
     8641 tgatctgctc cgcctaaccc tgctacttga cagtttttat tcaagttcag ccagccttct
     8701 tttgtttcca gaacaaattc atcaagtaat ccttgatgtg atttcttcac ttgtggaagc
     8761 cattcttctt tgttcagcag tcccaaacgt attcctttag ccattgcgta aacaaacata
     8821 ctactgccgg aagcttccag ataatttcct ttccgttttg tttctgttgt tacttgatac
     8881 catgtcccgc tgttttcttc ttgatatgga agtaatgcag ccagtgtctt ttctagaatt
     8941 tctttcagca aagaacaatc tgtttcttca tgaagtaatt cataggtatc tgctgcagcc
     9001 atcaaatacc agccaatcga tcggctccaa aaatgatggg atagacctgt ttttggatca
     9061 gcccatggtt ggaccttctt ttcatcccat gcatgaatca gcaaatttgt ttttggatcg
     9121 aatagatgtt tataactgat ttcaaactgt ctcaaaacat cttggtaatc tttttcttca
     9181 ctaaaattct ggataaattc agcataaaaa ggagaaccca tatataagcc atccaaccaa
     9241 atttgataag gataaatttc tttatgccaa aaagctcctt cggatgtgcg tggatggttt
     9301 gccaactgct gggaaaggag ttctgctgct tttttatatt tttcttcgcc tgtttctttg
     9361 tacaataaaa agaaaagctt tcctgtattt acatggtcga tattgtattc ttcaacgctg
     9421 tagccacgga tcgttccatc ttcttgcacg aaatagtcga tattgtcttt tatgaaatca
     9481 aaataaattt tttcttgggt tcgttcccaa agtaattgga accctttaag tacgacgcca
     9541 tagtcataag accattttcc tttataccac ttttcttcat ataagcgagg tgttctttcc
     9601 atgatacttt ttgctaattt ctttgaccag ttttccatta tttgctctcc tttaaaaatt
     9661 aaaataggat ttgggacaaa taccaagaag tatttgtccc aatcgtctat attactgtgc
     9721 cgctgctttg tatgcttcct cgtactcttg tgtgattcga tcgcctcctt gtgctttcca
     9781 gtcttctaca gcttttttga atccatcttc gtcaagctgt cccatgatgt attgcaccgt
     9841 agcatcaatg acgatttttt caatttctga tcctacttca ttgttcgtcg gtgaatccaa
     9901 tggcacagaa ggatccatta cagcaaattc ttcattttct ttgatcaatt gattagagaa
     9961 ttctttttca gggtctgtat ctttgaaaga gaacgtcact tcactaggac gagagcttga
    10021 taacggttgc acctcttgtt gccaaagatc catatcgata aattcgatag aaccatcatc
    10081 attcaattca taatgcgttc cttcgatacc gccagtcatc aatttataca catcttcttc
    10141 taaaagatca tcaacaaatt gaagtaattt cttcaattgt gcttcgtctt ttacttgaga
    10201 tttgggaaat gctagcaagc cgccaatacc atttccttct gaccaaacat gataaccgcc
    10261 gccttcacca tctgagatct tgtttacagg cactaattcc atatcatctt gaataccttg
    10321 acccatcgtc ttcagattct tgatatccac cattccagtg tagattccag ttcttccttg
    10381 tgcaaattgt tcttgctgat cagtcttttg ggtaactgca aagtcttgtg ccaaatagcc
    10441 attctcaaat agatctcttg aaaaattcaa agctttcata tactcttctg tatcaaattc
    10501 tggagtgaat ttgccattat cgtctacagc ccagccattt ggtgctccaa aataagaagt
    10561 gaaaagttta aagctggtat aacgaatatc actaggcgca cgatcgccaa aaccaactgt
    10621 gtcgtccaca ccatttccat caggatcgtt ttctgtaaat tgtttagcta cttcataaag
    10681 ctcatccatg gtagttggaa catctagtcc tagattatcc aaccagtctt ttcgaatgac
    10741 taagccagca cgagcgtagt ctttttgtat cggtacgccg tacaaggcac cgtcgatact
    10801 cgcagcttcg attctatctt cagaaatttg acttaaattt ttatagtctt ttaaatattc
    10861 tgatacatcc cagaatacgc ctgattttaa cgcattgcgg acagaagagt ttttcaacat
    10921 cgcaatttga agtgtaacga tatctcctag ttcatcagaa gccaatgcag ttgttaatct
    10981 ttcttctttt gaagcatcag gaatccagtt gaatgtcagt tccgtatcgg ttttttcttc
    11041 gatcaagttc acaatcgtgt ctgtaggcgg tgaagcatga tgcaaaatat ttaaccaagt
    11101 gattttagct tttccatctt ctgtctctga agaactgtta cttgaactgc tgccgcatgc
    11161 ggcaagtgct agaattcctg caaaactaag acctaatttt acgagcgttg cttttttcat
    11221 aaattttctc cttcactgtt ttaataatat ttttgttttc ttctgttttt tctgtatatg
    11281 agttcttcca ttccaaatgg caaaatatag aatttgctgt ccacgtgact gcggaaaaga
    11341 agagactgcc accgataaag gttaaaacac ctggcattgt ttggatgatc atcagataaa
    11401 tccctaccat acttaatatc aacactaatg agtaatgaag atgtgagaat ccgaataaaa
    11461 atgccatttt cattttgaaa aaatatcctt tccaatcata atgagccatg attgggaaaa
    11521 tatagagtgc tgagagcaca tatatgaacg cagcaatata caaagcgatc ctaagatacc
    11581 aattgtgtat gaaagaaaga tccacaagta aaacaatccc gatggcgcca tatatccagc
    11641 tcatcagcaa ggtttcacga tagttttctt taaaatatgt gaagtacgtt ttcgtcaaag
    11701 gaaacgtttc ttttgagcgc agccattttc taatcactgc aaccatcgca tacgatgcag
    11761 gaccgaaagt aaaaactccc aaacctgcga tgactaaacc gccccacaga aaattcaaat
    11821 aaaccaactg taaaatacga tttagccttc cgtttatttt atctaatgac tgcagcatat
    11881 ctttccctct ctttctatct tagtaaacgc cgtcttctcc tagctttttg gcaatcttat
    11941 tagctaaaat taccataaac aatcctacga cccctttaaa caatcccatt gctgtactga
    12001 aacttaactg tccattcttc aatccagctg tataaatata ggtgtcgaaa atttctgcaa
    12061 cgcttcgatt caatgaattc aataacaagt acatatgctc gaaccctaag tctaatgtct
    12121 gaccgatttt tagaatcagc aaggtaatga ttactggacg aattgccggc aatgtaacat
    12181 gccatgtttt gcgtaagcgt cctgctccat ccatttctgc agcttcatac aactgtgtat
    12241 cgactgcagt tatcgctgaa aggtagatga tcgtagacca gcccaactct ttccagatca
    12301 cttgtccgat atatactgtg cgtgtccatt caggggatgt tagaaaactg attttttcaa
    12361 atcccattgt tgcaaggaat tcattcaata cccctccgtc aacattcaaa aatacataag
    12421 taatcgaaac aatgattacc caagacatga agtgagggat gtaaatgatc gtttgaatcc
    12481 cgtttttcaa tcgtttgttc gttacttcat ttaatagtaa agacaaaatg attggcatcg
    12541 gaaaaaacac gaagatattt aatccgaaca agatcaacgt atttcttaat aatgtaaaga
    12601 atgtcggttc tgtaaacaaa cgaatgaaat gtttgaaacc gacccaagga cttcccatta
    12661 ttcctaaaaa tggttgataa tcttgaaaag caataacgag tccccccata ggaagatacc
    12721 taaaaatcaa gaaataaagg actcccggca gaatcatcac atataaaaat ttattcgttt
    12781 tgattcctgc aattattttt tttcgtcttc tgagcttttc ttcttttttc gatagcgtca
    12841 gttgaaatgg ttcttgtttc tttacacttt ccataagccc ctccttagtt ttgtgaatgt
    12901 ttgctgctta tgacttcatg atagataact atctgaatta cgtatataat catttttacc
    12961 gtaagtaaaa acgcttacat agcaatgatt tttgtgctat acaaaacgat aaagtgtatt
    13021 ttttcacaaa taaactacgc atagcaaacc ttctattttt ttctatctga cacttagcat
    13081 aggaaatgat tatatacgta atctttcacc gatgataaat tgaacatata gaaacagaaa
    13141 catttaattt attttgagga ggagcctatc tatatgaaaa agaaagtctc tataggagaa
    13201 agaagtttta cacttttcaa caatacgttt ctaattttgc tagctttgat ctgtatcgtt
    13261 ccttttttaa atatcatcgc tacatctttt gcttctacac aagaagtcgt cgcgaaaaag
    13321 tttatccttt ttcctactac cttttcttta gacgcgtatc gctacattct ttctacgccg
    13381 accattttta gagcacttgc tgtttcgatt ggtgttacag gtgtcggaac gatcgtcagt
    13441 atgtgtgcaa cttcactgat ggcctacggt ctttccagaa agtatttgtt tggtcgaggt
    13501 ttcgtcaact ttcttgttgt attttctatg ttgttcagcg gggggatgat tccaacgttc
    13561 ttagttgttc gttctctagg gctggtcaat tcttactggg ccatgatcct gcctgtggct
    13621 gttaatgcaa tgaatatgat cattatgaga aactttttcc aagccttgcc ggatagtttg
    13681 gaagaatcag caaaaatgga tggttgcaca gattttggtg tatttttcaa aattatgctg
    13741 ccattagcgt taccgtctat tgctactatc tcgctttttt atgctgttac ttactggaac
    13801 acttatatga ctgctatttt gtatatcaac gattcatcta aatggccgat acagattctt
    13861 ttacgccaaa tcgtcattgt atcaagtggg atgcaagcag aaagtagtgc cgttgatgtg
    13921 attccaccag cacaaacagt taaaatggct gttatcgtta ttgcaacagt gcctatgctg
    13981 attgtttatc cttttgttca gaaatatttt gtcaaaggag cactcgtagg ttctgtcaaa
    14041 gggtgattat gtactgaacg caaaatggta gttgtgtcag aagtggtcag cttcaagaaa
    14101 taagaaggca tttacgaaaa ttgcttctta aatttttgtg aaatttcggc ttatttttcg
    14161 aagaatctac tcctggaaca ccgtgtatca gaggttgtga aagagacgtt cagccttgag
    14221 cgatgataaa aactctcaca aacattgcga cgagtaaccc acaggagcaa taagaagcga
    14281 ttttgaaaaa tagcttccca tatttcacaa aattatgcct tattgtcgat agcctgtctc
    14341 ttgaacgcca tttattcgta aaaaagaact gtgacaagac ttttgtcaca gttctttttg
    14401 cgtgcttagc cttgaaattt aactatccat aaatacaaat actagggtta ttctaacttc
    14461 ttttattgct tgaatcagtc cacaagaaaa acagcctctt gattcacaaa tatttttttc
    14521 gatattctcc cggcgtaatc gattccttct ttttaaagaa acgaataaaa ttttgcggat
    14581 ttcgatattg caatctttct gcaatctctt ttacggagag gttagtctct ttcaaccatt
    14641 tttttgctac ctctaaacga tgattttgaa caaaatcacc aaatttttct cctgtttcct
    14701 ttttaaatac attacttaaa tagttagggt tataatgcaa cctatcagcg atcacatcta
    14761 aagacagatc acgatcatat tctgtgtaga cgatatgcat aatattctcc gacaaatttt
    14821 taaattcatg atcagtgatt gcttgagagc attctgtgat tggcagaact aattgttcta
    14881 aaacaagttt ttctagttct ttgggatgat aattgttcag tgcttttaca taaatttgtt
    14941 tcatgttatc aaagtttttt gaatctactc ccaataactg tcctaattga acgagttcat
    15001 tgatcaagcg gaccgaaact acttcccgac tcaaaggatt tttattttgt gcaaacaatg
    15061 catcaatcaa ttcatgtact aaattcttca cttcctgatt tccagaacga atggcttcaa
    15121 acaatcgatt ttgttcttct atcggatatc taataagtgt tttttcatga gcagcaggaa
    15181 cgatttcctg ataaaaaata attgaacttg gaccagtatt tacacgataa tacagggctt
    15241 cttttgcccg atcaaccgat tgcttgcttt cattcagcgt ttcgaaccgg ttactgatgc
    15301 ctatactgat agttaaattc aagtattctt ttacacgttt ttgaatgagt cggcaatact
    15361 ccatgacttt tttgcttgct tctgcatcat ctttatccat tcgataaata gtggcttgca
    15421 tttcttcatt caaaacgatc ggcagcattc gattttcctt tggcacaatt tccgtgatca
    15481 tgttgttgat cgctaaaagt agcaaatcac gctccccacc gtgactatct tctaacagat
    15541 cgatttgaac caaagctgta taatagcagt cattttgaga actataacca aattgctgca
    15601 accgctgatc tagttctcgc ctttctactc gatttctaaa taaactaagt acaaatagcg
    15661 tttccagctg tggcttttgg gtaactaagt gtgcacttaa cgcttctttt tctcctatga
    15721 tccgactgac tgattgagcg accaaatcta gttctttccc actgaatcct tttgatttaa
    15781 gattcagacg ttcctgtatt tgagaaatcg gacgggcaaa tctgtccgaa aataagtagg
    15841 aaagaagacc aatgagtcct accagtgtta aagacactgc aactagcccg attctcagat
    15901 tgcggatcat tgcgccaatt gcactagagt caacttctaa tctgtaaatc caattattat
    15961 aatctgattt cagtactata tacgttttat ctttttctct tatcactttc agctgattgt
    16021 aatctagatc cacgtccgtt aatacagttg gttgctcttt attttttact gtctgagtag
    16081 taaaaaggtt gccaacttcg ttttcaatag aaagtatgtc ttctccactt tcaccaacaa
    16141 cttgttctat tgtatgtttc tctatcgtag caattcccaa tgcatatttt tctttttcaa
    16201 acattggcaa agaaatcacc atttcgattc ctttgttttt cttttgccaa aataaattat
    16261 ttttgttatt tatgtacttc tgttgatact tttcaacttc ctcttcggtc agttgactca
    16321 acgatccatt gattactccc catttaccag ccaaactgac taaatcataa ttattatcat
    16381 ccataacaat cgtttctata aaatttagtt ctttcctgat ttcagaataa gtggagtaat
    16441 ctgtatatgt cagcggatgc ttgaatatgt ccgagaaatt tttggtcgaa ccatacgtag
    16501 aaaacgaata ttcaatcgtt ctaattttcc attcaacgtt agttttaact tgcctgagca
    16561 aattcttttt gtctgttaaa taactcgatt cgatcgattc ataggtattc tggtaaatga
    16621 ataaactaaa tcctatgaca agtacggctc ctaataaaaa catcggtaaa aatattttat
    16681 aaaatactgt acttttcttc attttcttcc tctcctcctt ttaaaataaa aggctttcat
    16741 ttttctgtaa aattgatact catctaatta aatgagcatt ccccgctttc aagaatagca
    16801 taattaaaaa taaaaatcca agtaattttt aacgtgtgca atcttttcat atcaaagatc
    16861 tattgactta tcgtagttat cgtaatatga tgaatgcgtt aacaaaaagt gaaaaagtaa
    16921 ggaaaatgat ggaatggtaa cgatcaaaga tatcgctaaa gcagctggcg tttctcatac
    16981 gacagtttct cgtgctttga ataacagcag tttaataaaa aatgaaacaa aacaaaaaat
    17041 acgacaacta gctaaggaaa tgaattattc gccaaactat agtgcaaaag gtttagtgaa
    17101 tcaaaaaaaa tatctaatcg gactattttt ctcaagtttg cataaaggaa cttcatcaaa
    17161 tttcctagca gattccattg caggcatcca ttcagtatta gacacaaatt acagtttatc
    17221 tgttgaaagt atcgatgttg ttgatttaac agaaatcaac ctgcaacgct acgatggact
    17281 gatcgttatg agtcaaagtg atgatgatca gcctttcatc gactatctca aagaaaaaga
    17341 atttcctttc gttgttgtca atcgtcacat caatgatcca gcggttatca acgtcactgc
    17401 cgatgatgcg gccggtgtta tgcaggcagt agattacggt attggatgcg gacatacgaa
    17461 gatcgcttat attggcggaa agaaaaattt tcgttcgaca aaagaacggg aaaaaggggt
    17521 attgaaaagt ctaaaaaaag cgagcatccc tgtcaatcca gcctattttt taacaggaga
    17581 ttacagctta gaaagcggcc tccaaaacat ggaataccta ttatcacttt ctgacctgcc
    17641 tactctggtt ttttgcggca acgacgacat agcgattggt gcattgagag ctgtacattt
    17701 agctggcctc cgtgttcccc agaacatttc tctgatcggg ttcgatgatt ctccagtcgt
    17761 ctcctatctc aatccgccgc ttaccaccgt acgtaagcct ttgaaagaaa tgtgtcaaga
    17821 aggaacaaag cttttactag atttgatcga aggcaggacg atcgaacaat ctaaaattga
    17881 gctctccacc ttgttgatcc ttcgtgagtc gatcaattac ttgtaaacta caagtaattt
    17941 tatataaaaa tgttaacgtg tgcataacac agaaaggaag tttatatgaa aaaactgaca
    18001 aaagaattag tgaaaaaaaa cgaagcacct gtaaaagttc ttcagtttgg tgaaggcaat
    18061 tttatgcgtg gatttattga ttggcagatt cagcagctga ataaccaaca attgtttaaa
    18121 ggtaatgttg caatcattca acctttagaa caaggtcttg gaaatatgat gaaccagcaa
    18181 gataatttat atacggtcat tttacaagga ctcagcaatg gcgaaatcgt tgatacttcc
    18241 gagattatca ccgtagtaga acaaatgatc aatccttatg atgaatggga tgcttatcta
    18301 tctctagcag aaaatgacga cttggcctat atcgtctcca atacaacaga ggcaggaatc
    18361 caattcgtgg agactgataa tttaacagat actcccccac agagcttccc gggcaaactg
    18421 acagcctttt tataccgacg tttcaaatta aacaaagctg gctttaccat cattccttgc
    18481 gaactgattg acagaaacgg cgaacgtcta aaagaaatca ttttacgcta cgcagaaaaa
    18541 tgggatttag aacctgcttt tgttgagtgg ttagaaaaag aaaatgtttt ctgttgtagt
    18601 ttagttgatc gcatcgtccc aggttatcct cgcgaagatg caggtgtttt caatcaacgg
    18661 cataactatg aagatcaatt gatggtcaaa gcagaaccat tcatgctttg ggtgatcgaa
    18721 gggcctaaag aattggagaa tcaactacca ttcaaacagg ctggcttgaa tgtcatcatc
    18781 acagatgata tgactcctta tcgtgaacgt aaggtgcatt tgcttaatgg accgcataca
    18841 gcgatggtcc ctcttgcttt gttggcggaa ttggaaactg tagaagaagt aatgaaagat
    18901 cctttattct ccgcatatgt tgatcagtta ttcaatctag aattgattcc tatgctttct
    18961 ttacctaaag atgaattagc catttatgct gaccaaatca aagaacgttt cttgaatcct
    19021 tttgcccatc acaaattaga agcgatttca ttaaatagtg tttcaaagtt cagcacccgt
    19081 ctgcttccag tgttcaagaa gtatatcgaa gaacaaaatc aggtaccacc gttaatcact
    19141 gtttcactag ctgcgctact tcttatgtat cgaggcgatc aagtaaagcc acatgatgat
    19201 gaaaagacga taagcgaatt tactgatgct tggtctgata atggaacagc tattcctcga
    19261 ttattgcaaa acgctgcgct ttggggagaa gatttgtctc aaataccgaa tgtgacagat
    19321 acagttcaag aaatagctgc aaagatcgat caaaaaggtg tccggtcagt attacaagaa
    19381 atgaaaggaa cgatggtcca tgcttgaaac cctgcaacca acaatgaaat taaatcgacg
    19441 agacagtgtg gtcgtcgcat taacccctat tccaaaacaa acacaactga cgattgatca
    19501 gcaaacgatc accactcttg aagatatccc gcaaggtcat aagattgcat tgggtgattt
    19561 gaaagctgga gacaacgtga tcaaatatgg ctatccaatc ggtcatgtga cgacagacgt
    19621 aactgccggt caatggctgc acactcataa tgtaaaaacc aatctttctg gtgaattgga
    19681 ttatcgatat gaaaaagatg tccatccaag tcattacctt tttgagaacc gaacatttca
    19741 aggttacttg cgaaaaaatg gaaaagtagg gattcgtaat gatttgtttt tagtacctac
    19801 cgttgggtgt gtgaatggca ttgctgaact gatcgtcaaa cagttcaagg aaaaacatcc
    19861 agatctggga cagtttgacc atattacgat tttaaagcat ccttatggct gttcgcagct
    19921 tggaaaagat catcaaaata ctcgagaaat tttagcggac gcagtaaatc atcccaatgc
    19981 cggaggagtt ttagtatttg gattaggttg tgagaacaat acagttcctg aattcaaaaa
    20041 aattttaggt gaatatgatg aagaacgagt gaaatttcta gtggctcaag atgtttacga
    20101 tgagatcgaa caaggtgtgg ctctattaga agagctttta acagcggcgg aaaatgacca
    20161 gcgcatatca gtcccgctct ctaagttgaa tgtcggtttg aaatgcggcg gttctgatgg
    20221 tctatcggga ataactgcta atcctttact tggtgcattt tctgactact tgattgctca
    20281 aggaggcagc acgatcttaa cagaagtgcc agaaatgttt ggcgcagaac aagtattgat
    20341 ggcacgagcg gaaaatgaag aagtttttga ctcaatcgtt gacttgatca atgacttcaa
    20401 acagtatttc ttgtcttacg gggaaccagt ttacgaaaac ccatctcctg gtaataaagc
    20461 aggtgggatc actacattag aagataagtc tttaggctgc acgcaaaaat caggaagctc
    20521 tcctgtcgtt gatgtgctac aatatggcga aaaaatcaga aaaccagggc ttagtttatt
    20581 gcaagctccc gggaatgatc ttgtagctgc ctctgctctt gcttcatccg attgccagtt
    20641 ggtcttgttt accacaggaa gagggactcc gtttggctca tatgtcccaa cggtcaaggt
    20701 atctacgaat acaactcttt ttgaacgcaa aggtcattgg atggatttta atgcaggcgt
    20761 cttattagaa caaccaatgg aagtaatctt agaatcgttt gttcaaaaaa tcatcgctgt
    20821 agctagtgga gaagaaacga aaaatgaaca aaatgacgtt cgagaaattg ccatttttaa
    20881 aaacggagta acactttgat tttcataaaa cagtataaaa agaaagaagg aagatttatg
    20941 tttttatctg atgatttttt attaaaagac gattgggcga aaaagcttta ccattcctac
    21001 gcaaaaaaca tgcccattat tgattatcac tgtcacttag atccaaaaga aatttacgaa
    21061 aacaacaatt tcagcaatct gacagaagct tggttaggag gcgatcatta caaatggcgc
    21121 ttgatgcgag cttgcggcgt gcctgaagaa aaaatcacag gaaatgcttc tgattttgaa
    21181 aaatttttag cttggtgtca aaccgtacca aaaattatcg gaaatccgct ttacagttgg
    21241 tcacatcttg aattgaagcg tttcttcggt attgacttgt tgataaatga agaaaatgca
    21301 gagaaaattt ggacacaagc aaatgaaatt ttggcagctc ctgattttcg ccgtcgggaa
    21361 atcgcaaaaa aatcgaatgt agaagtgatt tgtacaacag atgatcccgc agacgacttg
    21421 cactatcatc agttgcttgc tcatgaagaa ccagatttga aggttctacc ttcattccgt
    21481 ccagataaag cactcaatat tgaaaaagaa ggatttaatg catgggtcac actactggaa
    21541 gaagcagctg accaaacgat caccacctat caagaactga tagaagtctt agggcagcgg
    21601 atagaatact tccatcaaca tggatgtcgt gtttccgacc acgctttaga catcttacgc
    21661 tataaagaag cggatgaaac agtattagaa gagatttttc aaaaagcacg agctaacaaa
    21721 ctattatctt cagatgaaat cgatgcttat cgtacagaaa cactgataca tttgacccac
    21781 ttctatcatt ctcataattg gacgatgcag ctgcacatcc atgcttatcg taactgtaat
    21841 acacaaatgt tggaaaaatt agggcccgat accggctatg atggaatgaa tgatctttct
    21901 ttgactattc ctctgcaaaa attattgaac cgtgcagaag aaacggatca gttgccaaag
    21961 acgatccttt attcattgaa tccgaatgac tatcctgcga ttttagcttt gatgggctgt
    22021 ttccaaaaag aacagaatgg aaaactgcag ttaggttctg gatggtggta caacgatact
    22081 cgagctggta tgcgcgatca attgacacaa tttgctgatg gtagtgcttt ggggaatttt
    22141 gtcggcatgc tgacagattc aagaagtttc ctgtcctaca ctagacatga atatttccgt
    22201 cgtgttcttt gtgaattttt aggcgaaatg gtcatgcgag gagaagcacc tgaagatgaa
    22261 caacttttag gaagtctagt tcaagcgatt agttatacaa atgctaaaaa ttactttggc
    22321 ttttttgcct aattgattaa tagtaacagt aacgaatcaa aaacaggata gtgaaataac
    22381 ggaatccgtt tatccacgtt ttagagaaga agacggacca aatttgctcc gtcttcttct
    22441 cttgctgttc tgcttcattg cctataaacc tttatgaaag aagagataac atgcctacta
    22501 tccatattgc cggtgattct actgcggcag aaaaagatga aaacaagcgt cccgagacag
    22561 gttggggaga aaaaatctct gcttattttt cacccgagat ccagatcaat aaccaagcaa
    22621 agaatggacg cagcaccaaa tcatttatcc aggaaggaag gttagcccgt ctagcttcac
    22681 agtttcagcc gaatgatttc ttatttgtac aatttggaca taacgaccag aaaatccaag
    22741 aagaaagagg tacgcttccc ttcggtagct atttaaaaaa tctgcagata ttttttgaat
    22801 gcgcaaaaaa agcgaacgtc caaatggtct tactgacatc tgtgacgcga cgagattact
    22861 tagaaaacgg aacattgaat ccagatatac ttggagacta tccaaaagcg atgcgtgcat
    22921 ttgctgagaa acaccatatt cctcttttag atgtgttctc aagatcacaa gaattgttcc
    22981 agaccttctc aaaagaagag acaaaaaaat tctacctgca tcttatacct gatacttgta
    23041 aaaattaccc agaaggacta aaagacaata cccactttag tccagaaggc gctgataaag
    23101 ttgcccgaat aattgttgaa ttgataaaag aatcccgtct gcctcttgct aattatttac
    23161 aaaaaggagt ttgagatgtt tccattaaat ttaggcatcc gtgcccacga tttagatgtt
    23221 cgaaatcgtg aagaaatcgt tcaaaaagta tcacagcttc acttgtccca tatccaattt
    23281 gcaccacaaa aagcatttcc tgaacaactt aaattaactg acatgacact tgggagtgct
    23341 gcctattttg gtgaatactt ccaaaaaaac aatatcgaac tttccatttt aggatgctat
    23401 atcaacctat ccagcaaaaa tcaagaagtt cgtgcacaag cattggcaac tttcaaacag
    23461 caaattgctc tgtgctctgc ctatcaagcc aagatgattg ctacggaaac cggtagtgtc
    23521 tctgtcggtt acacaaaaga aaattttact gaagaagctt atcagatcgc cagaaattct
    23581 atcattgaat tagtcgctca tgcagaaaat tttggcgtaa ctgttgctgt tgaagcaggg
    23641 atcaatcatc caatctataa ctatcagtta gctaaacgtt taatcgatga agtagcttca
    23701 ccaaatttaa aaatcatttt agattgtgcg aatttgatgc ataaagaaaa tcatgctgat
    23761 caggaaaaag tgatccgagg tgccttggac aatttacatg gttatattac agcgcttcat
    23821 ctcaaagact atatcatgga aaatggaaag atccgcatgg tacctgttgg caagggctgt
    23881 ttagatttcc gcccggtact gcattatatc aaatatgagc gtcctctaat gtacgccact
    23941 cttgaagcta ctcctgagat ttatgttcct gaagcaatag aacacttgca gtttatttac
    24001 caagattgtt aaggagaaga ttatggagga acgaatacag aaaagttatc aaaaatatca
    24061 tgcaaatgct tttcagacat tgctgcatct ttatcaggga aattattggc gttttgccat
    24121 gtcaggactc ttttttatta tcaaacatct tccatcttgg ttaatgccga tcgctattgc
    24181 caatgtaatc aatgcagctt catcgaaaga ttcttctcag ttgcaggcca tttatttcaa
    24241 cgcttttttg atggcttgtc tgattggtca aaatatattg acgaattatt ttcatgtaaa
    24301 ataccatagc acttcgatcc gtcaagtaga agctggacta agagcgaccc ttatcaagaa
    24361 aatccaagaa ctatctattc cttatcaaaa agaattgcaa tctggacgaa tccagtcaaa
    24421 gatcatccgt gatgtagaag ctatccaaac gttgtcctct caagtatttg tcagcggatt
    24481 aaatatcgct gtcaatttat tcgtagcttt aggtatcacg ctttataaaa gtcctgttgt
    24541 tttcatgttt ttcttattga ctgttcctct cgccgcattc gttactctct ttttccgtaa
    24601 aaggatcaga cagtccaact cagacttcag gcaagaaatg gaagagactt ctgcaaaagt
    24661 gatcgaagtg atcgaattag caccgattgc tcgagctcat gggttagaaa aacacgaaac
    24721 aactcgctta aataagcatt ttactcaaat ctatgaaaaa ggattccact tagatatcct
    24781 gcaatctgtt ttcggatcag tcagctgggc tagttttcag atatttcagc tgatttgttt
    24841 gattttcact gggatattag ctttacaagg gcgcatccaa cccggcgatg tcgtgatgta
    24901 tcagacgtat ttcacgacga tcgtcaattc cgtttctgga atgatcacgc tgattcctac
    24961 gatttcaaaa ggcatggaat ctatcacttc tattggcgaa ctgttgattg ctggcgatgt
    25021 agaaacttat cacggtaaga aaaaaatcca acatttggat ggaaattttc gttttgagga
    25081 tgtttctttt ctttatccgg actcactcaa accgattatc gatcattttt ctctagaggt
    25141 gaaagctgga gaaacaattg cttttgttgg gccatctggc tctggaaaat ctacactcct
    25201 taacttattg attggattta tccagccgac ttcaggaaaa atttttctag atgatcagcc
    25261 tttggatgaa ctggatatgc gaagtgtgcg aaattattta gccgttgttc ctcaaaccac
    25321 tttgttgttc tccgcttcga tcaaagagaa catcacttat ggcttgaaaa acgtatcaaa
    25381 agaacgttta gatgaagtca tcgaagctgc gcaactttct tcactgattg accagcttcc
    25441 tgatggtctg gataccttag taggcgaaca tggcaacaag ctgtctggtg gccaaaagca
    25501 acgtatctcc attgcacgag cgttgatacg tcagccaaaa atcattttgc tagatgaagc
    25561 aacctcagct ttagataacc agtcagagaa aaaaatccag caagccctga attacctgac
    25621 agaaacaccc actactttta ttgtggctca tcggctttca acgatcaaag aggcagataa
    25681 aatcgttgtg atcgatgaag gaaaaatcgt tgaaataggt acttacgaaa aactgttagc
    25741 tcaaaaaggc tatttctacc gcttgaaaaa tgaatgacaa aaaataggag ctatgacaag
    25801 acttttgtcg tagctcctat ttctgaataa acggtgttct cctgccaact cctcggtcac
    25861 aagtcacaat agtcatcaaa catgagaagc tgttttttga aattgttcct tgtaactcag
    25921 agttaaacgg taggctcacg acctcttggt aaatggtgtt caagagacag cctatcggca
    25981 ataagaagca attttgtcat cgctcaaggc cgaacgtctc tttcacaccc tctgttgttt
    26041 cataaaatag ttttattcgc tgtaaaggtc gcgaactggt gtcatgatga tacggttcaa
    26101 gtcattgatg attgtactga agccttgctc tttttgcatc aagtcattga ttacttcttc
    26161 tgattggatt ttcacagcca tttcttgtgc tttcattgca tcttcgtcgc tgaactcttg
    26221 tccactcatt tgtttttctt gtaattcgat ttgcatcgct tggaagtctt tgaacagttt
    26281 gtgtgcttct tcgtttgctt gtactttctc gtacgcttct ttcaacgctt tgaattctgg
    26341 taattcacgg atctcacgtt cgatttgatt cgcgctatcg tagatgtttg acatgttatg
    26401 ccctcttttc ttttagtagt tactctctat tgtaacatgg ggttattcgt tttcaaaggg
    26461 gctactctcc ttgatatttc cgccagaggt ctttagccgc ttcaccaatt ccctgaacgc
    26521 cttctttcac catatcgccg aagtttttca gcccttcttt tgcttgttca ccatattgat
    26581 tcaagttatc ttgccaattt ccagactctc cattagaatt tcctgtgttt ccaacttgat
    26641 ctgcagctac cacttgtcct cctgtggcat aggcatctgc tacactaaat cctgtttttg
    26701 aagtatacgg aaggatgcct tctgccgctg atttgaagac tttcccgaca acatttccac
    26761 ttgtcccttc caaatagtgc agcttgctgg attcttcgta acccatccat gtcgaaatca
    26821 ctacgtctgg cgtgtaaccg atcatccatt ggtcatttgc ttttgtggca tcgaaattag
    26881 tttctgtggt tcctgttttc cctgctatcg tataacctgc aggattcgca gcagccgctg
    26941 ttccatttga aaatgtacca agaagcatgc tggtcatttc atcggctgtt tcctttgata
    27001 tgacctgttt tggttttttg tttgtgttat cgacgatcac cgctccagtc gaatcaacga
    27061 ttttcgtgat aagatgcggc gtatacatct gaccatcatt ggcaaatgca ctgtaagcac
    27121 ccgccatgat caatggagat actccttttt ccagtccacc aagggctaag ccataatact
    27181 tatcagattt tgctaaaggc aggccgaatt cttctgcttt atcatatcct ttttgtaaac
    27241 cgatctcatg caaaagccat acagtaggca aattcaaact ttgtgcaaca gcttgataca
    27301 tcggtacttc tccttggtat gtcccgtcaa aattatgcgc atcgtaataa ctttgcggtt
    27361 cgtctttcaa gatactggaa ggcttgtatc cagcttccag tgctggtgta tatacgctta
    27421 atggtttgat cgttgatcct ggtgaacgac gcatctgtgt agcaaagctg aatcctctaa
    27481 agacatgatc tcctcttcgt cctactagtg cttgtacacc acctgtattc ggatctaaag
    27541 ctactgaagc agattggacc atggcaccat ctgaagcatt tgctgggaat aatgcactgt
    27601 tttgataagt agcttctaat tgcttttgat aatcctgatc taaagctgta tagattttat
    27661 agcctttatt catgacatct tcttcatcaa gaccatactc gttaactgct tcatcgatca
    27721 ctgcatcaaa ataataagga taacgataac cagaatctga attatcgtat gtgtcattaa
    27781 gatacgcgct gatatctgtc tggctttctg cttgttcttg ttcttttgtg atttttccgt
    27841 tttcttccat tacacttagt actgtgtttt tccgatcatt cgcatttttt gggtgatcga
    27901 tcggattata aataccagga cctttcagca ttcctgccaa agtagcagcc tcagacagcg
    27961 taacattcgt tgcatctact ccaaaatact ttctggaagc gtcttggaca ccccataccc
    28021 cgttgccaaa ataggcattg ttaagataca tggtcaagat ttcttctttg ctgtacttct
    28081 tttcgatctc gattgccaaa aataattcct tcgcttttcg atcaaacgtt tggtctaatg
    28141 tcagatacgc atttttggca agctgctgag tgatcgtact tcctccgccc cctgatgttc
    28201 cgccagacaa gaccattcgg actgctgcac gggcaatccc tttgatatca aacccgtgat
    28261 gctcgtaaaa attcctatct tctgtcgaga ttactgcatc ttggatatag ggagaaatcg
    28321 cgtttaattc tacatatgtt cctttttggg cgtacagtgt gccagcttct tcgtttttct
    28381 tatcataaat gactgtcgat tggcttaatc ctgattttaa cgtttcgaca tttgcttgtt
    28441 ttgctaaaat aaagaggtag atacttgtca ctaagacaca gatcaaacca atcagcaaaa
    28501 tcaatttgtt cacatgatat tttttccaga tgcgctttcg ccatcgatgg aattgtccga
    28561 gatatggtct gatccaacgc caaaaactga tcaaagcagc ttttatcttt tctaaaatgc
    28621 tttgaaaatc catttgcttc ttctcctgtc tatttgattc aatcgtctta ttttaccata
    28681 gtgaaagagt gttttcttcc tgcttaagtt gtagttcaat atgttttttt acgttagtgc
    28741 aagtagagta acataagaat gaacagaaaa atgtaagttt tttcttaaat atgttttaaa
    28801 aatggtacaa ttagtctgcg attgcactga aaggagtaca cttgtgaaaa tcacgatcac
    28861 tttacctatg aaccatcctg aaacaacaat tcgcgacttg cttgaaaagg aatggttagt
    28921 tcctagaaag gttcgacact ttttgcgtat acgtaaaaac gtttggatca atcaacaacc
    28981 tgctttgttc catcatgaag taaagggcaa tgaccagatc acattgttat tcgaagaaac
    29041 agattataat tatcaagaag ttcaattagg agatgcgaag cacatccgtg ttttatatga
    29101 agatgagcat ttgattatag tggataagcc tgcaggaatg aagactcatc caaatgaacc
    29161 gacagaaaac agtaccttac tcaatcattt agctgcttat ctcgacacta aacagcaacg
    29221 accttacgtt gtccaccgct tggacaaaga aacaagcggt gccgttttat ttgcaaaaaa
    29281 tccatttgtc ttgccgatac ttggaagaat gttggaacaa aaaatgatct atcggagata
    29341 tcaagccatc gtatggggag aaattgccaa agatatgacc atcaccaata aaattggacg
    29401 agatcgccat gatcggagaa aaagggtcgt agatgataaa aatggtcaga gcgccttgac
    29461 acatgtcact gtcaacaaag tactttctga acaaacacaa gtctattgtg ttttggaaac
    29521 cggacgtaca caccagatca gagttcattt agctcataag ggacatccga tcgttggaga
    29581 ccctctctac caaaatagaa cagctgaacg actgatgctc catgcattag aactgcacat
    29641 gatccatcca tttactcaag aaaaaatagt cggtaaagct ttacctggat tatgggaata
    29701 gaaataaaaa agaacagagt cttatcagca gataatgata agactctgtt ctttttgtgt
    29761 aatttgtctg cttacttttg atgttcgtgt tctgctaaca gcaaactacc gataatccca
    29821 ctttcattcg gcagtcccca acgaacgata tattcactta cttgaggtgt ttccatataa
    29881 ccacccatca attcaacaaa ttgctgacgg attttttgaa ggagatgatc ctgattcatt
    29941 accccaccgc ctaaaataat cttttcaggt gctaacgtca acgtatagtt gatcagtgct
    30001 tgagcaatat aataagcctg aatagcccaa acaggatgat cttgcggcag atcttgccct
    30061 ttgatccctg tgcgtgcctc aatagacggt cctgctgcta atccttctaa acaatcttta
    30121 tgataaggac aagtaccttc ataatggtca tctggatggc gtttcaccca aatatgtccc
    30181 atttcaggat gtgcgatccc tgaaaaaatt tcttcattga tcacgacacc tgcaccgatt
    30241 cctgttccca cggtaaggta aatacaacta ttttttcctt gtgctgctcc ttgcttcaat
    30301 tccccatatg cagcagcatt gacatccgtt gtccaagcag caggaatatt gtagcgttcc
    30361 ttgattgtgc caagaaaatc gaattgtgcc cacccttttt tgggagttgc caaaacgtat
    30421 ccgtaattat cttttgtttt gtcgatacca atcgggccga atgagccaat cccgattccc
    30481 ttcaattcat aacgatcaaa aaattcaaat acctgatcca atgtttcttc tggtgttgtg
    30541 gtagggatac ttaatttttc taaaatttct ccaccatctg aaaccgcaca cacaaatttt
    30601 gttccgcctg cttctattcc gccatacatt cgttttcctc ctcgaatccg attgtccgaa
    30661 tctcataagg ttggattatt gggacaaccg cttgcttcgt tggttcttca agcagattca
    30721 atatgacagt ttttccattg tctttagtta tttccaattt ttctaaatga ctagacatat
    30781 tgaaacctct tactactact ttatcactaa acttgctgcg tttcaaagct gtaattgcaa
    30841 acgtttcact ttttatcgtt aaatattgtt gttttgaaat caatgttcct tcatgatgtt
    30901 tgatttgttg agtggaaaaa ggaatctgtg ctgcgtatgc atgcaaataa gtagagaatt
    30961 tttcttctgg tccatgtagt tcaatgctgt aattgaaccg atgctcacct agacactgtg
    31021 cttctggtgt tggaaaatat ccccaatcgc ctagttctcc cacactgcga agtagcgtca
    31081 ctgcgatttg tccgtcttct gttacttcat attcattcaa accaaagttt ccgactgtta
    31141 caccgtactc ttcatcatga atattgacaa atgcttgctg atgttgcgga ttcgtggggt
    31201 tttcccaact tttagacaca tggtttgggc gcttcaccac ttcaaaaata ctatctgctt
    31261 cgtgatgttc cacatgtaac tttgtaggaa acaagacacg taagcgatga tctttcatct
    31321 gattgtcgag agtcgtttca aagtcgattt ttttactatc ttttctgatt gtcatgattg
    31381 tttttatttg aaggattcgt ttttctttgg atcgttctgc ttttcgataa cgaaattcca
    31441 caaccatctg ctgttctttt tctaaacgct cgtctgcaga aacagggatt tccatttcct
    31501 gtagaatact tatttttgct atttccggtg tatctactaa tacttttact tcagagtttt
    31561 ctttgttact ggataggatt ggctgatcac agaaaggttg tttaaagata tactcatttc
    31621 ctatatcgcc gatatcttca aaaatatgca gattattcaa ctttcgtttg tttttgcgat
    31681 cttccattgt aatggtacca tttttttcaa tcgtcaaatg tagagggccg ttttcgatga
    31741 ttcgtccact ctgatgaatc attgtttcct tttcttctgc tttcgcttcc ccttctacaa
    31801 gcgcgaatgt ttcccaagaa aatgctggca tgttttctaa tggtaaagtc actttgatca
    31861 ttcttgccat atatggcaca cggaaacggt ctttcggcaa atcataacca aattggacag
    31921 tttcttcaga taaaatagct ggtatagtgg ccccactttt tgtttctaca tgatacttac
    31981 gtttaggcaa attttctaac tcttgatata gttgttcagg tattccttca gcgaatcttt
    32041 ttctttctaa ttcgatggtt atttctgctt caccagtttt atccattcct gcagtattta
    32101 caatgacaaa tggaaagctg tcttttggga atccggtcgt atcgattgct gcggtcagct
    32161 gttctaagga atcttgtgca agatactttc caacttcatc tgctttttca aaacgaggta
    32221 tcatttcccg atggacagaa tcgactgaac aaccgcaaat actgtcgtga ggatgatttt
    32281 gcattaatgt cttccaagca taatctaatt gatcatgggg atagtttcca ctaacttcat
    32341 aagccatcgt cgcaagtggt tctgtaatat tttctagctg tcgctggacc ttggtattcc
    32401 attgttttaa gtaaacccga gcagatgctg tattggctaa agtataccag ccatccgttt
    32461 cttgacttgt caattctcct tctactgagc ctaagtcttc tggcacatct ttttgaactg
    32521 cttccagata gtcagtaaaa ttagaatgaa taaactcgta atctggaaac agttcatttg
    32581 cgagatggat tgcttttgat atatcttttt gtaccggttg atgatcaaca ccattcatca
    32641 tcaataagtg gttcgtagag gcatattgtt ctgcatccgc taatttttgc ttccaaaagg
    32701 caagagctgc ttctttttct actggaatct cattcccgtt gctataccaa ttggcaaata
    32761 gcagaccaaa gattgctgtt tgatcaggtc ctttccacca catctctgag tattgggaag
    32821 aatagttttc tgcttccaaa acttgattat caaagccaat tggttttaca ccacggccaa
    32881 acgctgctgc tgaaatacca gcttgtttca ttaattgagg cgtctgtccc atatttccaa
    32941 atgtatcggg aaaatagcct aacatgacag gggttcccca tttacggctt tcttccatgc
    33001 caatcagcat atttctcacg ttcgattccg agctgataag aaaatcatct tgcaagatat
    33061 aaaatggtcc aattctcaat tttccttcat tgattgcttg ttggattgcc tgtctttttt
    33121 ctggccttac ttgaagatag tcatctaaaa taatcgtttg cccatccaaa tgaaaactgt
    33181 tgaaggacgg atcaacttca aatagctcta gtagatcgtc tatcaattca atcagtcgca
    33241 tgtgatgctg ttcgtaagcc atgtaccatt cacgatccca gtggctatga gaaatgatat
    33301 atactttctt tttcatttac gatacctcct acttttctac tctaatatca aagtaatcca
    33361 tgactaattc gcaaaacatc atatttgccc aagaaaacca ttctctcgta taattttcag
    33421 gattgttcac atcgaatcct tcgtgcataa ggtgtgttcc tgcgtcagtt gctacaagta
    33481 aattcaatat ccgctctttt tcagatttgt ctgacgttgt cattccttcc atagctaatg
    33541 caatcggcca aacgtatttt tctggcgtat gggaggatcc aattcctttt gcgtactttc
    33601 cttcatagaa atatggattt tctttactca acaatgttct tcttgtttgc agataatctt
    33661 cctcttgttc agaacaatat cccaagtaag gtgcggcgat cagattgggc acattactgt
    33721 catccatgac tgtggcgttt cccattccat ctacttcata tgcataaatc gtttgccctt
    33781 tttgattaac cgttcgtccg tgattctgaa tcccctcttg gatctctttc ttcaatttct
    33841 gtgtttgctg tacaatttct ttatcatcga gtatcgtttg aaaaatttct tccacataac
    33901 ctaacacgac caccgcaaac atattggatg gtaccagata tccataacgg caagtatcat
    33961 cgctaggacg gaaaccagac catgtcattc ctgtaaaagc tgtttttgca cctcgcccgt
    34021 cattgatcag cgtatcttct tttcttgtcg tgtctcgtac aaatgtataa ggagagtgtt
    34081 catgatcttg ctctgttttg aacacgtcca agattttttt gataccttca ataaaagatt
    34141 gattgaattg atcagttttt cctgtatttt tgtaaagaag ataggccaac tgtattgggt
    34201 agcataaaga atcaatttca tattttcttt cccagatcca atcgttcatt tttgtatgat
    34261 ctgtttggtg gccagcaccg ttagcttctt cgttgaaggc attcgcatat ggatcgatat
    34321 tgatataaaa aaattgcttt ttgactaacc cgctgatcat gtcagctaat tcctcatctt
    34381 cttttgcaat cactaaataa ggacgaactt gtgcagtaga gtctcttaac cacatcgctg
    34441 gaatgtctcc cgtcaataaa aaggtggttc cgtcattttg ctttttgact gttgtcaaca
    34501 gagtattggc aaatgctgct gtaaaattct ttgcccagtc cgcatggata tccccacatt
    34561 tttgtgtgat atcttccata aatttctgca ccgattttgg tatatcttta taagccacta
    34621 ataaaacctt ctttctattt gatatatctt taaagattat acttcataca gccaattatg
    34681 tctacgcttt caaaaaatat ctttttattt actttttcat ccattatggt attatttgaa
    34741 tatgatatat cattaagagg tgtttatatg aatcaaccat tgtaccagac aatatttaat
    34801 gatttgcaaa cggctatttt aactggtgaa ttacctgtag acagccaact accaactgaa
    34861 aaagaacttt cacgtaccta taaagtaagc agaatcactt ccaaacgtgc attgactgaa
    34921 ttagagcaat taggacttat ttatcgcgtt cgcgggaaag gcagtttcgt taaatccgct
    34981 tctccggaac agattcttgc ttctcctaca aaaacacgac ggattctgtt tcttcttcca
    35041 tatgtcgctg atttgtctgt tggtgatttt agcaagggat tgaaccctgt gatgcaagat
    35101 aaacagattg atgtcatgat gacgacgctt gactttctac aaaataaaac agcaaaagag
    35161 ctaatcaatg aatttgacgg attgatttat tatgctcttg atacagaaca acatcttgac
    35221 ttactttttg agctttcatt gaaagaattc cctgtcgtca tattagataa aaaaatctat
    35281 gagttacctt ttcctaccgt tctttccgat aatttccaag gcggtgcgct tgctgcctct
    35341 tatttgatcg aacagggaca ttcaaaaatc gcttatttgt ttggtacgca gactcatcca
    35401 caatccgttc gacagcgtta ccttggttac cttgaagcat tggacaaagc tggtttgact
    35461 ttccacactt cactggatga caaaagcgcg acattagatg aattgctttc ttatatcact
    35521 aagtatgaag taactgcttt tgtttgtgaa aacgatgttg tcgctatcca gaccatgaat
    35581 ctcttgagac agcatggtta tcatatccct gaagattttt caattatcgg atttgatgat
    35641 atccaagcag cagctcttgt tgacccgcca ctgacaacca tcgcacaaga ttttgaacag
    35701 ttaggtaagc ttgcgggaga tgctttggtc acttggttag agacaaaaga tcgaccatcc
    35761 gatagtaaat ttccagtttc attcatcaaa agacaatcaa caaaggagaa ataaaatgaa
    35821 tatcggtcaa atagatacta gacatgcaac agcgaatcag ccaaatttct ctaatgggaa
    35881 ctgccagcct tatactggcg ttccttttgg gatgaattat tttgcaccgc aaactacgga
    35941 tcaaaacggc agctggtggt ttcatcctga tgaccgcgtt tttcaaggct accgtcttac
    36001 ccatcaacca agtccttgga tgggtgattt cagtcatatg ctgtttacgc cgatcaatgg
    36061 aaaactacag gagaacaccc ttttccatgc tcaaagttct taccgcccag aagaaagtat
    36121 attttgcccg actcatctgt cgatctgtca attacgttat ggcatctgtt ctacattgat
    36181 acctagcatg tatggcggaa tcttatctat tgattacagc aaaaatgaca gcggtttact
    36241 tttatccttt ccgggacgcc atcagctctt tgttatagat ccttacacag tggaaggaaa
    36301 aatcacacat tttgctggtt cagaagatcc tgatttttct ttttatttta tattgagatt
    36361 tgaatatcct ttaacaattg atgagttagc tgtttccaac aaaaatagcg actcgatccc
    36421 gttgtatttt gaacagacaa aaaaacaaac tatccgattt gggacatctt ttatcagctc
    36481 ggaacaagca gcttataacc tggaactaga acaaaaccaa agcaaagaga cttaccttgc
    36541 tcacagtcaa gaacaatggc agtcctattt tgatcgtata cagctcacac accatgatca
    36601 acaacaattg cggacgtttt atcataattt atatcgggtg tttttatttc cacaaacatt
    36661 ttatgaaatt gatcctagtg ggcaaaaaat ccactatgat acgactagtc gatctataaa
    36721 acctggtgtt ctctatacaa ataatgggtt ttgggatacg tataaaacgg tttatcctct
    36781 ttattctttg attgctgtag aaaaatacga agaaatgctg gaaggttttt tgaacagcta
    36841 tagagaaagt ggctatttgc caaaatggct gtctcctgat gaacgtggac ttatgcctgg
    36901 gacattgatc gatgcggtca ttgcagatgc tgctgtaaaa gatatccgac gagacttgat
    36961 gcctgaattt ctaacggcaa tggaaaaagg tgctacggtt caaagcaaac atccaaatta
    37021 tggacgccaa ggaacagaag attacttgac atatggctat gttcctaatc actaccacga
    37081 atcagtcaat cacacattag actatgctta tagcgatttt tgtattagcc aagttgccaa
    37141 ggtactagaa gaagaggaaa tgacgaagaa atatcagcag caatcattga actatcaaaa
    37201 tatctttgac tatgagtcag gatttatgcg ttcaaaagat aaagatggca agttcagaga
    37261 accattttca gctaatcgtt ggggacaaga ttatgcagaa ggaagtgctt ggcaaagcag
    37321 ctttgctgtt tatcacgatt tttcaggact gatcggaaaa tatggtggca gtgagagata
    37381 taaagaaaaa ctcattgagc tgtgcaatca gcccccaacg tttgacccag gaggatatgg
    37441 ttttgagatc cacgaaatga gtgagatggc cgcgatagaa tttggacaat tagctatttc
    37501 aaaccagcca agttttcact atccttactt gttcagttat ataggacaac ctgaaatggc
    37561 acagccactg cttaaacagt tgatgactca gaccttcgac gattctccaa tgggttaccc
    37621 tggagatgag gacaatggaa gtatggccgc ttggtatatc ttcaatagtc tgggatttta
    37681 tcctgtcacg cctggaaccg gtgaatatgt tatcggtatg ccattaattg acaaggctgt
    37741 tttgcttttg tcaaatggaa aggaattgac gattgaagca acgcctaatc ggccgcagca
    37801 acaatttatc cataaaatca aacggatgga caaagaatat acgaaattat attttaccca
    37861 tcaagatttg ctgaaaggcg gcacgatctc ttaccaatta gggatcatcc ctcaccctaa
    37921 gaaatatcaa gcaaaagatt tgcctttttc cttatcaaac tataattaac aagaggttgt
    37981 gaaaaagctg tcctgcatca agtaataaga acagccaagc aaaaatagat cctcatattt
    38041 ttcgtttggt tggtcttatt accgcagatg caagcttttg aacaccgttt attgagaggt
    38101 tgtgaaatca gcgttctgac ctgagtatta gagagacaaa tggcaaaata gttcctcata
    38161 ttttgccatt ttttgagcta ataccgaggg tcagctgatt gaacaccgtt tagtggagag
    38221 gtcgtgaaaa agctgtttag tttcgagtat taagaaaaat tttgtgaaaa tggctttcca
    38281 catttttgca taaatttggc ttaataccga gaaactggct tttgaactcc gtttatcgag
    38341 aggtcatgaa aaagctgcct tgcctcaagt aataagaaca gcccaaaatt agatttctag
    38401 acaatttttt ataagttatt tcattacatt ggctttttct tttatgattc tccactgttt
    38461 tctcggtact ctttagggga tctgccgacg attttcttga ataatttaga gaaatacgtg
    38521 gtgttgttgt agccaatctc acttgctatc tcattgatgt tttgattact gtgcaaaagc
    38581 agttgtttcg ctttttccat acgtaaatgg ttcaaataag ctgaaaaact ttttttcgtt
    38641 tcttttttga acagctgtcc tagatacatg acatttaaat gcaggttttc tgacacttct
    38701 ttgagtgtaa gtggttcttg ataatgctgg tgcaggatta cgattacttt ttccacattg
    38761 tcactgtact ttttctgtct ctgatgcttt ttgatgaatg acagaagtag ctgctgaagt
    38821 tcttgcaccg tttttgcctg atggattttt tcgattcctt gtaaatattc ctcatcttcc
    38881 agatcaatca attcccgttg aatctccata aacagtaaaa aactggaata tcgtatatct
    38941 tccggcatca tggctgctaa ctgaaactgt tcaaaaaaat cagtgatcat tttttgagcg
    39001 acttccaatt gtttattttg cagcacgcgt ctgaaacttg aaaaatcgat ggtttgatct
    39061 tttgtttctg cttgtactgc gtaaaaaaca tgctcgtctt tatctccata aaattgatgc
    39121 aactgtagat tgtctttcgc ttgttggaat gtttcaggga ttttgtccaa agaatctgtc
    39181 tcttccccga tactgatcag ccattcctga tcaggaaagt tttcttgaac aaaacaacag
    39241 aagccatcaa cttcatctgc ctccaacaac aacgtgatca atacacggtc tccgtaattt
    39301 cgttgatagt aaaagatttg ttgccgttct tgcaaccatc tattgataag agtatcatga
    39361 gttcttgcca gttgaatcaa tactatccta tgctgcttct cacttatttg tcctattatt
    39421 tcttcttcac ttatttcatc caattcttca ttcaaccatt gactgaataa cagttcttga
    39481 tagatttctt gttgattttt ttgttcattt tgctgatcta accgtgtttt gattttcttg
    39541 aggctttcaa ccaattcgaa cttattcacg ggtttcatca aataattcac ggcgcctaat
    39601 tgcatacctc ctttcaaata atcgaattct tggtatcctg ataaaatcat aaattcaaaa
    39661 ttatgacgtt ctttttgagc cgcttcaata aattccagtc catttatttc tggcattgtc
    39721 acatccgtta ctactaaatc aatctgtcgc tgttcaagta cagctagtcc ttctttggca
    39781 ttctctgctg ttgctactat ttgaaagcct aaactttgcc aatcaattat cttttttaac
    39841 ccattcaaaa tcatgtattc atcatctacc aataacactt gatacacgct catccctcct
    39901 tgaatgtaat agaaacggtc agtccacctg tctcattatt ctcaagcgac atataataac
    39961 tgctgccgaa gctggcacgt aaacgttcat tcacgttttg cagaccgata gaaccgtgaa
    40021 gttccacttt aggatgagac agtttttctt caatctgttt tagccgtttt tcagtcatcc
    40081 cttttccatt atctttgatg atgatcctta cccgtttgcc ttcctgcaag actttgacac
    40141 ttagcgcatt atcgaatcga gtaaaatcaa taccgtgttt aaaataattt tcaactaatg
    40201 gctggatcac aaatttaggt acttcgatct tttccaaatc aggatcgatc ataaaatgat
    40261 aggctactcg attaggataa cgcatttgat acaaatagac atatttttcg caaaagtcca
    40321 gttcttcttt taaagtgatc gttttctctt gattcgtatt gtttcgaagc aaagcggaaa
    40381 acgcatacac aacatctgct aattcttcac ttccttcgct gattgcatac attcggatat
    40441 attctaatgt attatataaa aagtgtggat tgatctgtgc ttgaagcgcc cgcatatgtg
    40501 cgtcttgctg tttgatttct aatttgtaga tgtcttctac aaactgattg atgctatcca
    40561 acatttcgtt gataccgatt gaaagttcct tcagttcata ttccgtgttt gttatgtcga
    40621 tccgcgtctc taaattccct gctgctgttt gatccatggc ctgcatgacg atagatactt
    40681 gctgtgaata tcgtttgaat gttttataaa gaaagataag cagtatattg tctaaaataa
    40741 tgataccaat gatcagcggg gcaagatttt ttcccgtttc gatttttaca ctttttttat
    40801 ctagtacagc taatatacga taatcatcag acagttcttg gtgttgaaca aaattgtttt
    40861 tttccagatc gtcaatcggc aattgtgaat ttttcttcag actctctgtg atgatcattt
    40921 cttgtctttc aaacgtttct ttagctattt tattatcatg gaatgtgtat agtcgatttg
    40981 tcgttccaga aatcatgtat aaagagagtc cattgaatga cgttagattt tctaaaatca
    41041 tatctagttc tttcttttga aaaccaataa aaatacttcc tgactcagct cctccttgtg
    41101 tgataggcaa cttgatataa aaggcgtcta gtaattttgg tgtccccttt tttatttccc
    41161 cacctttgtt ttctctagaa gattcataat actccggtag ttgattcaac acgatatata
    41221 tcgcacttag ttcttcataa tttgcgtaga gatctttgat ttgatttggg aaagaaacta
    41281 attcatcggt actgttttgc tgttcgtata catacatcag atactgatct atgggttttg
    41341 ttaagtaggt cgtcacattt tcgatctttt cggaattccc tacaagctgg tttttgatga
    41401 tcctactcaa ggttgtttta tcattcagca ttctgcttgt gctttgaacg gcatcacttg
    41461 tcatgttttc tgcctgtttt tgattttgtt cccaagtatg gatactaaaa ataacggtag
    41521 cagtcatcgt tacaccgatc atgataaccg cgtatttccg caacagacga tttagtaagg
    41581 ttccttttga aaatagaatc cgaaacttat tcataacttt ccaactgttt atctaattct
    41641 tcacgccaat gtgttgtcat cgtaccattc caaaccgtca aaagaccaat gacaccaaac
    41701 aggatcaatc ctttgaattg ccaagtcacg cctaaaatta taccgctacc aataattatt
    41761 tttagaaaag acgaaaagct ggaaaaaacc gaaataaaac ttagctttag cagattagga
    41821 acagagatcg tatattcact atctaaaatc atactgtatt gataagtagc aaataggcag
    41881 agcaaggcaa aaagtaaaat aaaatcaata gctaaaaaaa tgagcccttt gatttgaaca
    41941 gataaatata aattgtaact caataaagca gtaccagata aaaataaact aaatagcaga
    42001 ttgcctctta aaaaatttct tttatatata ttccagcctc tttttattgt gatttcttta
    42061 tactcgaatc cgtacaaata aaatagttca ttgactgttt tccatgccgc acctaatcca
    42121 aagatgatcc cgccggcaaa tgtatatatc cagaaataca aggttagttt tataatgacc
    42181 cagatccgga taaataactc ttccaaaacc ttccctaaca tatcttctcc tccaaacatt
    42241 aagtttatac tttctcatta tacaaaaaaa ggttgggcaa tcagcacctt gacctgatta
    42301 ttagagaaac aaacggaaaa atagttcctc atattttgtc gttttgtgag cgaataccga
    42361 gggttagctg attgaacacc gtttaccaag agtttgtgaa atagccgctt agtttcgagt
    42421 agtaagaaaa attttgtgaa tatggctttc cacattttta catatattta gcttaatacc
    42481 gagaaactgg cttttgaaca ccgtttattc ggaacaagag gttgtgacac gtcttttgtc
    42541 acaacccctt tgtctttatt cattattatt cttgtcggaa ctcatcatat tgtttttgca
    42601 tttctttcaa taccttatca tagccagcct tgtccaaagc gtctttcaat ttcggtaatg
    42661 tttcatctgg atcaacagtc cctgtattca atccatctaa atattgattc atgacattag
    42721 aaatattact taattctgtt ttgacactgt cagtgttgaa gctgaatcct aaaatcggtg
    42781 aagtttctgc atcagcaatc gattgatcac gtttggcaat catgtcatcc gtaatagact
    42841 cttgtgtata tagaatcttg ttgtttcctg tattccaagc agacatatgt gtatttggct
    42901 gataaccatc tagcaatttg attttatcat ctgaaccatc gactttttcc catgcttctc
    42961 cctcgatccc ccaaacaagc ccattcaata attctggatc actgttaagc agccctagaa
    43021 gttctactga tttttcttta ttttttgaag tatttgatac gacaaaattt gccatttgtg
    43081 cttgagctgt agattttagt ggaacagtaa ttgcttttga gacaagttct tgttttgctg
    43141 catttgtcaa aattgtatcg ccataatcat acggtccttg tgtttctcca cgcattagcc
    43201 aagtatttcc ttctagtgga taatccttat tgctcgttgc agcgtcactt ggaatgagtc
    43261 cttgtttgta ccagctatgc attgtacgta acagtccgat atacgtttca ttatcgtatt
    43321 ggttgatgat tttcgaatca tctccatcca gatcaatagc aaatggtaac gtattcccta
    43381 aaggataatc aaagttccct tggactttga agccttgtcc aatggcaaaa gctgccgtgt
    43441 ttggttcttt ttcatggaat tccttcaaga ctttttctgc atcagcgtaa gattggattc
    43501 catcaattga aagatcgtat ttatctagta aagctttgtt aaaagtaagt acttgttgag
    43561 caaagacatt tccattgact gggaaagcat ataattttcc attgaccaga tttcctttaa
    43621 tatatgcttc atctaaatca ttataagctt tttcagcgta cttaggcgct aattcagtca
    43681 aatcagcaaa ggctcctttt tgggcattgg aaacatagtt gttcgcaaag gcgatatcat
    43741 aattttcccc ggaagaaatg atgacgttca ttttcttttc gtaatcgccc cagccaatgt
    43801 aattgatatt gacttttaca ccgatctctt tttcgattcg tttgtttgct acttccatca
    43861 attgatcgaa attatctggt ttatctccga tttgatacat ctgcaaagtg tccgaattgc
    43921 tagcttctgc ctggtcttta gaaccagaac ctccgcatgc tgctaatgtt cccaacaaca
    43981 acgctgaaac acctgtaaag gctagtttct tccataactt catttttctt cctcctaatt
    44041 ttatgattta tatttttgtt tctttattct tttactccgc cgattgttag acctttgaca
    44101 aaatgcttct ggaaaaatgg atagctgatc gcaataggca acgtcgagat gactacgatc
    44161 gccattctgg cagattctcc tggaactgag gctaatccgc ctgtcaattg gcttcctgct
    44221 cctgaatttt gtgtcagata ttgaatatta ctttggattt tcatcaaaag atactgtagt
    44281 ggaactagct tatcatcttg gatgtatagt aaagcattga accagtcatt ccagtaaccc
    44341 aatgcggcaa ataaactgat tgtcgcaata cctggaacag ctaacggtaa aacgatctga
    44401 acaaatattc gcagttcgct agctccatcg atccgtgccg attcaataat cgaatcagag
    44461 accgaacgtt taaagaatgt gcgcatcaca ataatattga agggactgac agccattggc
    44521 aagatcaatg cccaaatcgt atcttttaac tgaagaagat ttgtcataac aagataattg
    44581 gccaccatcc ctggtgagaa caacatcgta atcaaacaaa aaacggtaaa aaaacgacgg
    44641 aatggaaagt ttgaccgtga aatcgcataa gcatataaag aagtagccgt gctattgatc
    44701 agtgtaccta aaacagtaac aagtacagtg acgaaaagcg cttggaaaat tttatcctgc
    44761 atctggtcga acaagtacgt ataaccaaat atactgaact tttctggcca aaaactgtac
    44821 ccgtgagtcg acaatatgga ctcatcggta aaagagatgg cgataacaaa tataaatggc
    44881 aaaatacagg aaatagcaaa gagtgcaatc attatattag agaaaaaatt agccgtctta
    44941 ttgaaagagc ggacttggac tctctccact ttcttttttt tcattttttt cctccttaga
    45001 ataatgcaga atcgctatca aaacgtcggg cgatcgtatt tgtgatcatc aacaagacaa
    45061 agccgacaac tgattggtaa agtcctgcag cagccgtcat accaaaatct cctgtggatg
    45121 tcaggccatt gtagatatac gtatccaaaa cttgagtcac atcatataat gcaccggaat
    45181 tcctaggaat gttataaaac aggccaaaat cagctcggaa aatgtttcct acggctaaaa
    45241 tcgttaaaat cgtcattagt ggaataagtt gtggtatcgt cacatgtttg atctgctgcc
    45301 atttgctagc tccatcaacc atagcagctt cataataagt cggatcgatt cccataacag
    45361 atgcaaagta aataatgctg ttataaccaa tccctttcca tgtaccaatg aacaccaaga
    45421 taaacggcca atatttcggt tcattatacc aattgacagc ttctcctcca tgtccagtga
    45481 tccactgatt gaatattcct ttgtcaggac ttaaaaaagc gtaaacaaag taactgataa
    45541 tgacccaaga tagaaaataa ggtagtaagg acatcgtttg ataaacttta acgagtcgtt
    45601 tatttctcaa ctcgctcata atgattgcaa atacgactga gatcagcaga ttcaaaagga
    45661 taaatgctac attatataaa attgtatttt tagtgatgag aaatgcttga tccgaagaaa
    45721 ataaaaattt gaaattttcc caacccaccc aaggactttc cctcaagcta gccaagaacc
    45781 catctgctga aatatgaaaa tttttgaatg ctacgacatt cgccattaca ggtatgtaaa
    45841 agaaaaaaat catccaaagc atacccggta cagccatcag gacaagtgct ttataacgcc
    45901 atagattcat aaaaaaatga ttgaacccct ttcgtttttt catctaaaaa cccctttcga
    45961 ttcattcgca acgtaattat agcgctttca ataatgagaa taaataaaca aagtataggg
    46021 aaaatgaaac aaagtatagg agaggttgtg aaatcagcgt tttggcctga gtattagaga
    46081 aaaaaacggg aaaatagttc ctcatatttt gccgtttttt gagctaatac cgagggtcag
    46141 ctgattgaac accgtttatc agaggttgtg aattcagcgt tttggcctga gtattaggga
    46201 gatcgtgtcc ttactatcta actctgagtc acaaggaaca atggggactg taacaaaagt
    46261 cttgtcacag tcccttattc cgaacaaacg gtgttccaga agtagcttct acggaaataa
    46321 gccgaaattt cacaaaaaag ccatccgaaa gtcagacgga caagtctgct tttcagatgg
    46381 cgctacaact actctgctta ttcttttagc tatccattca attatttttc tctcacttgt
    46441 tctagctctt ctttggtcat gggtcgatat tgccctttat tcaaatcttt aggcagccaa
    46501 aattttccca tacggattct ttttaaatat aagacttctt ttcctactgc tttgaccatt
    46561 cgcttaactt ggtgaaactt tccttcatgc aaaatcagac ggataattga agtttctgtc
    46621 tcttgatcta cttgatcaat ttggagtttt gccggcaatg tctgctcatc gccatcaata
    46681 atcagtcctt ctgcaaataa acggatatct tcttctgtca ttataccgct aacctcagct
    46741 agatattctt tctccacatg ttttttaggt gatagtaact gatgggcaaa caccccgtca
    46801 ttcgttaaaa tcaagaggcc ctctgtgtct ttatctaatc ggccgactgg aaaaagatct
    46861 tcccgataat cctggtcttc caataaatcg attacggttt gatcatgatt atcctgagta
    46921 gcagaaatga ctcctgcagg tttatgcaaa atgtagtaaa aatctttttg atacgtaatg
    46981 atttctccta aataagtaac cgcatcttcg aattcattta cttgcgcttt atcgcttttc
    47041 accacttgtc cattgacttc gatcgttcct tttttgatta atcctttgac ttctttgcgg
    47101 ctgccaagtc ccatatctgc taaaaactta tctaaacgca tgcgtttccc ccatttcaaa
    47161 agagcatcaa tctagctctt ctgattcact tattttattt ttaatttatg tcgtaaacgc
    47221 gctattcctg gtcctagtag tctttctgcc aagcggattt tcaaagctaa ataaccatac
    47281 actaaagccc ctatacctgc tactacaaga atcaacaata gagactggaa tttgctatct
    47341 tcgtttaaaa aagcaccaaa aatcatcttt gtgatccacg aagccaaaag cataatcaag
    47401 gtaagaataa agatcagcaa tgtcctgcgc cagacaaaac ttggtttaaa gcgggctact
    47461 tcatggattc tctttaagat caaggtacaa gacacagcaa atccgatcat tgtcgccaat
    47521 aaagggccgt atacttcaaa taaacgaatg gctgggtatt gaagaaggag tttcactaga
    47581 aacccaataa ccaaataatt aattgccgcc ttgttttcaa acattccttg cagcatgttg
    47641 gaaactagca tatatagtcc taggaagagt cctacaaaac ttgcttggat cagtacatta
    47701 cttcctagag aatccggtgt ataaaataat gtatttagcg gataggcaag taacataaca
    47761 ccaaatgtcg ccggaaacat aaaaaatgaa aacaactgta aatttccgct tgtcaatttt
    47821 gccagaccta ctcgatcttt caacgtaaca gcttctgtaa tcaacggtaa cccagtagac
    47881 gcgatcgatg ttgccaatgc aataactacc atcgtcaact tatctggatt ggcactaaaa
    47941 atcgaaaaaa gatccagtaa ctgtgcattg gaatactcgg tggatgcaga catgatcttc
    48001 ataaaagtga actgatcgac taatttgaag atcgttaccc ctgaacccac aataataaac
    48061 ggaatcgctt ctttaacggt atctaacaac aattccttcg ttgcaatatt tattttgttt
    48121 tcgctgtagt gaataaacgc cgatgtatac gcttgatgtt tcttcaaaaa atacaaaagg
    48181 acaagaatac ttgctagcat accgataaat gccgcgaaag ttgattgcgt gaccgccgtc
    48241 acatagtcac catccatgac tttcatgatg atgaatgtag ccaatagcat ataaaaaata
    48301 cgtgccacct gttctacaat ctgcgacagc gcataaggca tcatttcttg attgccttgc
    48361 aaataccctc gtatcacact catacaagga aaaaccaata cagcgatact caaagaacgc
    48421 atcgttggaa tcagttcttc tccgccacca gaagcatgag ctagccaagg agaggcgatg
    48481 tacatgaaca aagcaaacaa caggcctaac ccgcccatca tctgtaatgc acggataaat
    48541 aatcgtcgtg aagtgccata ttcattcaat gaattatagc gtgcagtttg ttttgcaatc
    48601 gcagcaggta ttcctgctgt agagatcagt agaaacaatg catatatatt gtatcccata
    48661 ttgaataatc cattggcagc cttagcattt tcgcccatcc aagcatacca gggaatgata
    48721 tagacagcgc ctagcaatct tgaaatgata ttactggcgg tcatccaagc agagcctcgt
    48781 gccatttttt cttgcggtgt taattgatct aatgctggtt ttctttgatt atccatcggt
    48841 cagattccaa ctttctacaa aacattacta tcattttaat tggtaaaaca gaaactggca
    48901 atcgatttta tataactttt ataagaacaa ttgttttttt gaattcggtt tcgttttttt
    48961 ggtaaagtaa agaaatatac agccttttat ggctaacatt tataggagat atcaatgaca
    49021 caagaaataa aaaaactacc cgttatattt ttaggtcttt tctttatcac agttggattg
    49081 aattggttct tgctccctca cgatatagct tccgccggag tgggcgccat cggacattta
    49141 gttgaaacgg ccttttctat ccaacgctca gttactgttt ggagcatcaa tcttatgatg
    49201 ctgcttctag ccgctgtcct attaggaaaa tcagtatttt ttaagactgt agcgggaagt
    49261 ctgctttttc ctgttgtttt agagattgtt ccaaaagtgg aaatgatctc ctcacatttc
    49321 ttttcactga tttcaggaag tcttttgttc agtcttgggg tttacacatt gtacacagtc
    49381 ggggcctcaa atggcggtat aacgataccg ccgattattt tccacaaatt ttttcggctt
    49441 ccaatgccgc aaggactttt acttaccaat agtcttatcg tctttttgaa ttattatgtt
    49501 tttggattgt tggagacact attcgttctc ctatctatta cagtcagttc attgtttatg
    49561 aaaatactca tccgcttgtc ccctgtgtca agaaaatttg aataaagctg gattttgtca
    49621 tagcggaaac aaacgatata ttaaaaagag tgtgctataa taaaccaaga aattgaataa
    49681 agcgagggat caatcaatga gcttctcttt agaagacatc cgtcatttac tattaaaaga
    49741 aaatctatta aaagaatttg tttcaacaag aggctggcat cttgatgtac cagaaaaagc
    49801 tgaatttctt cagttaagtt atgattcaag aaaagctgat gcttctactt tgtttttctg
    49861 taaaggaatg aatttcaaag aagaatattt ggattcagca atcgaacagg gtattcaata
    49921 ttatgtatca gaacaaccat acgaaaattc agcagtagga atcatcgtaa cggatatccg
    49981 taaagcaatg gcgcttcttg ctatggcttt ttacgactat ccgcaaaata aattgaaagt
    50041 gatcggattc actggaacaa aaggtaaaac aactgctgcg tactttacaa aagcaatctt
    50101 ggatcacaca acaaataaaa aaacagcatt gctttctact atgaatacaa cgttagatgg
    50161 caaaacatat ttcaaatccc atttgacaac gcctgagtca ttagatttat atcgtatgat
    50221 gtcagaagca gttgaaaatg gtatgactca tctagtgatg gaagtttctt cacaagctta
    50281 caaaacacaa cgcgtatacg gcttgacttt agatgtcgga atcttcttga atatctcgcc
    50341 tgaccatatc agtccgatcg aacatccgac atttgatgac tatttctatt gcaagcgaca
    50401 attgatcttg aattcaaaaa cagttgtttt aaatcatgaa agtgactatt ttgatttact
    50461 tagggaaaca gccgatctat tccagattcc aacgatcact tatggtcgtt cggaagaaag
    50521 caattatcaa gtgatccgtt cagataaagg tactcacggt tttactttat cttctcatga
    50581 agatcgctta gctatctgcg atactgctta tgatattttg ctggctggag gattcaacca
    50641 agaaaatgca gccagtgcga tcattgccgc agcactaaca ggtgcctcca gtcaagatgc
    50701 acaagacgga ttaaaagaag ctcgtgtacc aggccgaatg gatcaattga tccaatccaa
    50761 tggagcgcat gtctatgtgg actatgcaca taattatcta agcttgaaaa cattgctgaa
    50821 atttgccaaa aatgaacatc cagatggccg tgtaattgtt gtattaggca gcccaggaaa
    50881 caaagcaatc tcccgtcgac atgattttgg aaaagtgcta tcagaaacag ctgacatcgc
    50941 ctttttgacg gcagatgacc cagcatttga agatccgaaa aaaatcgcgg aagaaatcaa
    51001 tgaagcaatt actaatccag atttgatcgt tcattatgaa atggatcgtc ctgaagcgat
    51061 tcgacgcgct ttagcagaaa gcgctccgca agattcagtc gttattgcgg gaaaaggcgt
    51121 ggatccctat caaaaaatca atggtgtaga tgaaccttat gaaggggatt atgcaatcgt
    51181 gaagcggttg attgaagaat aatggtattt atatactagt ggtttcccat ttctaagaaa
    51241 aaaagggact gtgatttttt gtcacagttc cttttttctt agaaatcatt ttaacttttc
    51301 actagctaat tctgctgcct tttctctttc ttcatttaat aatttattat catagaattt
    51361 gataaatggg aaccagataa tgaatgcgat gattgcacaa atgactgcta acacagcagc
    51421 tttccaatca ccaccactac caacaaatgc tccgatcccg actggtgaag gccacggcat
    51481 ctgtgcaagc atcggtttga cgatttccag ccgaatggca aaataagcga gtgtagcaga
    51541 agccatcgga gctaagaaaa acggaaccgc taaataggga ttgtagacga ttggcatccc
    51601 gaaaatgatt ggttcattga tattgaataa tcctggtaca agtgaggctt ttcctaacac
    51661 tttcagctga tcagatttcg cgaggaatgc aataaagatg atcaatccta aagtcgcacc
    51721 tgatccacca acggttacat aagaattgtt gaattctcct gccaacggat aatttgcgcc
    51781 ttgtgcgtta gctgccatat tagctaatac gatcggggtc aagaaagaag tgatgatatt
    51841 cgctccatgg atccctacga tccacaatgc atggatcaag aaataaatca ccatgacacc
    51901 aagccatgta ttcgtcaact gcgtaacaaa cccaaatggg atagcaatca ttttgaagat
    51961 atccgttcct agtgcaacta ataatccatt gatgatcatc accacaaacg caatgacaaa
    52021 tgttgggatc agagcagtga aagaacgaga aactcctggc ggaacaacat ctggcatttt
    52081 tatgacccaa tttctcttga cacacataca atacaattcg accgcaataa tcgacataat
    52141 aatagctgta aagattcctg aagttcctaa acgttcgaca aaagagccca tcctaatacc
    52201 atttactaca gtttctgtct cattgataga agcaatcaag ctgattttac catcagtcat
    52261 gatcaattca gggatacaca taaagaatgc aaaaacagat agtaatgccc ccgtgagcgg
    52321 attaacattt aatttttgtt catctcgttc aattgacgtt aattcataag caaacacaat
    52381 ggcaaagtaa atagataaaa tccccatcgt cattgtattg acgatcatgt acaagtcact
    52441 aactttgaaa aaagttgcat taaaaaatcc ttctaaaaat gggaacggta atggcaaaat
    52501 atttaaaacc aaaaacatcg agcctacaat cgtgaaagga atagaagcca tccccgctgc
    52561 catgacagcc cgaacgattt taagttgcgc aattttcccc ataggtccca tcaggtattt
    52621 ctgcaaaaaa tcaaacatta gttattctcc tttcctaaat ataacgcttt ttcatattgt
    52681 ttaatacgga tatactgttg gtcttggttg agtgaaattt tctttaaacg atactgtata
    52741 aatgcactgg caaaaatacc gcttacaaca agaatgaaaa caaataactg tcctccattg
    52801 ttatttgcca taaaaggata caagaatgta aatcctgagg taaacaacac tggaatcact
    52861 aataaattaa agacactctg gaacaaaaaa taccactttg tccatggaac gttcgtttgg
    52921 tgttttcgat aaagctttac ttgttctcct actgcaggca aaatagctaa aatcagaatc
    52981 atcggtaaac tacttcctaa acttttagct gatagaagca gaatcatcca ttgcatgttc
    53041 atgaaaaaga aaaaggcagt caggtaacgt acgattagat aacgattgaa atacatgttt
    53101 ttcaaactaa gttgcttttt ttctaattcg attttccttt ttactgtatc ctgcacaatg
    53161 atccttcctt tctatttatt tttttgatac aaataattca tttcctgtgc aacttccaat
    53221 aatgtcatcg tcgtcatcag atgatcttgt gcatggacca tgataatttc catttctatt
    53281 tttgtcccgc tggcatattc tttcagaagt tgagtttgtg actgatgcgc atgaagaatc
    53341 tcttcatttg cttgtcgcaa cttctcttct acttcttcaa acatctcttt acgcatcgag
    53401 cgaaatgctt catgtatcag tgtccgtgca tttccgctat ggaaaatgat atcaaaagaa
    53461 gtcacttgta gtgtttcact gtttattttt tcagccatct gttttcctcc ttattcgatc
    53521 agtttgataa atttactgct gaaattctca aaaataggtt cagctaagat ttcctgctgt
    53581 acttttagct ggtcaactaa cctaacgatt gctttagtca cgaccgtaat tccttcattt
    53641 tcgacataag aaggcgaaac taaaaaaaca aaatgaattt cttgatattg atcccactgc
    53701 atcccagaag gaatcaatgc aacggctacc tttgtttcga ttccaactgg aacagcggga
    53761 tgtgggactg ccactgtatc actgaatatg atttgtccca tattttcacg ttgctggatc
    53821 tgctttcgca tttctcttat atatccttct tcttcattta tgctcagctt ttgcagcaaa
    53881 tcatgaagaa tttcttcctt tttcggttcg tacgtataag tcttgaaaaa tttttcagac
    53941 aactgttcgg tgtaaatctg ctttttttgc tgtagagaaa atgctggtat cggtctatct
    54001 gaggaatgat agggtataga ttctccaact acctttcgta ttttacgaac atcatcttca
    54061 ttcaaaaaaa tactgacatg taaaactgga attttgaaaa acattgtcga aagatcaata
    54121 gaagaaataa tcaggtcgat tccttttaaa gttgtttcat tgatctcata atagcctttt
    54181 acacttacca ctgtaatatt tttaccgaat tcactgacta cgcgattctt taatagttgg
    54241 gcactgccgt aacccgttgc acagataatc aatgcatgta gtttatgcgc agctctttct
    54301 ttttccaatg ccgccatgag atgcaaagcc aaataggccc attcatcttc attgatggta
    54361 tagtttttca aagccggcat gttgctgaaa tgccttttta ctgcgtcaaa gactttggga
    54421 ttttctttct ttatctcctc agtcaatggg ttctcaatgc gaatacctcg gctcaatcga
    54481 atcatcatcg gtgacaaatg atcgagtagt ccattgaaaa gctggagatc ctctactaat
    54541 gaaaaatgaa attcctgaga caatcttttc agaactttcg ctaattcctt tgatagttcc
    54601 tgatcatttt gattttcttt gtgattcgac ttagccatga gatgtaatgt caaataagca
    54661 atttcttctt cgggaaacga tacacctgcg attacctcaa tacgttgaac gatccgctgc
    54721 gccacttgat actctactcg cttagaaact tcttgttcga tgcctaattc cttgatttca
    54781 aacccttctc ggagccgttt gatccccaaa gccaagtgta aagtcagatt ctgtatgata
    54841 aaatccgaaa cttttaactt agcttctctt gtttcatcga gaatgataat gactagctct
    54901 tcaaaactga tgtctgggaa aaaacggctt tgccctaaat attctttcaa tgaatttcca
    54961 taatggtttc caaaaaaagt atccatgata aaatgccgtc gatttctttc ttccccttcg
    55021 atccatgtcc cttgaccatg cttagaaacg atttttagtg aatatggaat caatcgctcc
    55081 ttgatttctt gcatgtcctt tgtcaaactg gaacgactga tataaagctc ttctgccaaa
    55141 tcatccataa aaagaatggc atcttccaaa agcaattggt tcaatatata cttttgtcga
    55201 tcttcggact cataaaatcc ttgcggttct ctagcatatc caggtactat ttcttgccga
    55261 ctcaaaaaca agtcaaatgt cagtctttgt aaaatatgca gttggtagcc ataacctggt
    55321 ttagcaatga tcttacctcc gtttttttct actaactctt tgatccgctg caagtaatta
    55381 cggattgtcc gatcagataa taacaattca gaagctaaac gttgactggt gacatactcc
    55441 ttcttgtgat caatcaaata tctcaacagc aatttttcct tctgtttcat tatcatccac
    55501 tcctattcca tcatatgttc tcttcgatca cctctgctaa cttctggatg cctgtaggga
    55561 ttgggacata cgcttggaaa gggatactaa caacaggctt tccaacagat tctcctaatt
    55621 ttttgaattt atccaaaaac atcgtcgttt gcgggctgat cagaaataaa tcaaaatcac
    55681 tattcttaat catattatcg ccttctgtag ctgaaactgc atctacgagt acctcttctc
    55741 ttttttgctt aaagaaatcc gttgtctttg aggccatcat cgaggatgac attcctgccg
    55801 cacaaataat caatgctttt ttcataaatc aatcactcct tttattttta taaaccaagc
    55861 atatcttgta agcgttttct attcaaaata tatatttccg tagcattgcg gaaaaaatgt
    55921 gtatcatatc ttgaataata atttctggca ccgtgatata ctagtgatag aattttttca
    55981 ggaggggatt tagtgagtat cacagtgaat attttgtata caagtacaaa tggacaagcc
    56041 agaaaatttg cagaagaaat ggtcgaaaga aacattgtca aagcgattcg tgcagaagaa
    56101 ggaaacgaga aatatgacta ttactttcca ctagaagatc cagaatctct tttactgatc
    56161 gaccgttgga aagatgaaga agcaatcgaa aagcatcaca aatccgaaat gatggctcaa
    56221 ataaacgaac tccgtaaaaa gtataaatta aaaatgaaag tcgaacgttt cactgattta
    56281 ccgtaaaaag atacacatgg aatgatagca atttatcatc catgtgtatc ttcacttttt
    56341 ccttattttt tattcgatct catctaatga ttcaaaccgt gtttttctct tatttttcgg
    56401 ataagtattt cagtcacccc aatatacatg attcctaaac ataccccaag gatattctca
    56461 aaaatgcgga tcgttactgc tcctggaacc ccgaataaac tggcagtgat tgccaaagca
    56521 ccaaaagaat taaaaactgt tttatatcta taggtagaac aaacacctaa agctagacca
    56581 cctaatatac cgacccagtt aaaaggaata aattggctga taccaataaa taaaacacat
    56641 ccaatcaatg agccaatgat tcggtctact gctcgttctt tgaaaccaat cgacatcaat
    56701 ccatagctag atacaataga agaaaatgca aaccctgccc acatcaatcg ctgaaaaggg
    56761 acatactctc ctgcaacgat caaaagacta atgccaaatg catagatgag catccaaatt
    56821 ttttcctgcg aatacatgcc tttcaaaaaa atctctttaa acaagctttt gtctttgttc
    56881 ttttctcgat gttttctgta aaggagaact gaaaaccaac aaaaaaacaa aaataataag
    56941 ctacttgttt gtgtaaagaa attcttgttc aacgaatctt taggtaacga ataaacaata
    57001 aagagatatg aaaagccgta caaagaagca ttccccattt tgggatcact agcggttgcc
    57061 attaatatgc tgcttagtaa aataaaatga atcaacatgc ccataactga ccatttgatc
    57121 agctggacat acggtgctac taatagtgag aacatgacga ttgctaaacc tatgatcgaa
    57181 tgggaaatct tataaccaaa gtcaacaaaa cgaatactca tcaacataca gaataaaacc
    57241 acagcgtatg gtttatgctt cgattcaaat aatgttgtaa ttataatgat aaaacaaatg
    57301 gcaaacaata cgatgaataa tgatcgtaaa aacaatgaac aaatatacat gcacttttct
    57361 tttttagaag ctgcttctcg tattttttgt tttaaaataa acggatctag ttgtagagac
    57421 tgataaaaat ccacctgttg tcgtcctttc tttttacttt tattttttac agtcatctat
    57481 gacaggttgt aaatactatg gaacatcata tggcgttgtc attttcttgt caactatttt
    57541 tcctattcat gtttttataa aaaaacatat cgttttcttg tatgattaaa tcaccacaaa
    57601 ataaacaact gagagaacga tatgctttat gaatggttct atcaaaaaaa ttctgagatc
    57661 aatagacaaa aatttgatga ttacagaggt ctcttacgaa accttacaga agaaaaaaac
    57721 attgatcgtt gctgcagttc tcttccctgc tccatgtgtc tgtagaaatt gtggttctgc
    57781 tgtggtagat ggaaatagga aattaatggt ggtgaaaaac aagaagaagg aaaccattgt
    57841 ccactttgaa taatataatc atatgccaat ggttatacgc ctaaaaaagc agcgctatac
    57901 ctgtaaaaac tgtcgaagcc attggaacgc tcaaagttat tttatccgtc caaggcactc
    57961 gatttcaaat catgtcagac ataaaatcac ttctttactg actgaaaaag tgtcgttatt
    58021 ttttatttcg aaaagttgtt aggtatcttt gacaaccgtt attcgcacat tgaaagagtt
    58081 gagaagctat ttaccaaagt cttccaaaag aattctgtct tgagtgttga gggttgtgaa
    58141 tttcgttctc acgtttccgt tgaggataaa ctgagtttta tttccgcgga tggcgagaca
    58201 gaaaaattaa tcgagaaaat ttacctacac aaaaaattcc tcgattaaca aactatttcc
    58261 ttagctgcac taatcctaaa gaaatagaat tcttagttac agacatgaac gccacctact
    58321 ttcagctcac caaacatgtt ctaccaaatg cgaaattggt gattgatcga ttacttggtt
    58381 tttccacgcc tttcaaggag gcgtaacctt tattcacgag ttggttgaag ctttccgaga
    58441 caaaagaccc gacttgtttt tctccttatt gacaaagagc cattaaaact agagaaaaaa
    58501 ttacaactga tcgctgatta tttgtagaaa gaaaatcaaa gtattaccca ataaacttga
    58561 gtcattaggc aaaaaacact gcgaaactca agaatgattt tcgcagtgtt tttgtatatt
    58621 ttttattaac tagtattact acaaaggttt atttttcact tctcaacgca gcacaaaatt
    58681 gtctttactt atttactggt tgggttcaac cttctctact ccgatactaa tatttgtttg
    58741 tatacccctt ctaaaatcgg tagtttccat tcaattgatg ggtactagtt gattttaaaa
    58801 actatgctta ttcaattttt tattttagct catatatttc gtttctttct aaattttata
    58861 ctgatgaaaa caagtagcac acccaatatt gacaatataa actggctaat gatggtttct
    58921 ccagtttttg gaagatgctt atttccactg cttgttggat tgtttcctct tatatctgag
    58981 ctatcagcaa cttttctatt ctcttttgtt aaaaagatcg ccacttcttg ttctttttcg
    59041 atcttgaaag ttactggtgt cgcatccaat tcataccccg ttggcgcttg agtttctacc
    59101 agctgatatg ctcctggtgc taagccatct atcgccagtt ttccatctgc tcctgtggtt
    59161 agacctgact gcagaacggt tccattggca tcttgtaact caaaaacagc tccttgcagg
    59221 acttctccgc tttggtcatc gatctttgtc aacacgacac cgcctggtgt aagtcgattt
    59281 tctttcgtca attctaccac cgctgtctga cttctttcga tctcaaactc gattggtgtc
    59341 gcatccaatt cataccccgt tggcgcttgg gtttctacca gctgatacac tcctggtgct
    59401 aagccgtcaa tcgccagttt tccatctgct cctgtggtta gacctgactg cagaacggtt
    59461 ccattggcat cttgtaactc aaaaacagct ccttgcagga cttccccgct ttggtcatcg
    59521 atctttgtca acacgacacc gcctggtgta agtcggtttg ctttcgtcaa ttctaccacc
    59581 gctgtctgac ttctttcgat ctcaaactcg atcggtgtcg catctaattc atacccc
//
LOCUS       DADQDV010000010        58384 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.010, whole genome shotgun sequence.
ACCESSION   DADQDV010000010 DADQDV010000000
VERSION     DADQDV010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 58384)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58384)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58384
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.010"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..1197)
                     /locus_tag="J8S10_000642"
     CDS             complement(<1..1197)
                     /locus_tag="J8S10_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629253.1"
                     /translation="MFILDDEIKKVKNPRIIPLLEEVRSSFYQGNYRSAIAVNYSALI
                     LDLIDKLSDLANIYEDNTSKKILEDIARLRKSDPNSPKWEMELLEKAYSSTELIDSYE
                     YEDLKYIKDQRNYSAHPVVTYNGNTWELRDITKETCQDVIRKSYEIIFLKNPILGKKV
                     TIEIIQYASRIHAMSVTPEEFHSALKNSYLNKLSEKAKENLCKTAFKFVFQLSYGNEE
                     ADRNRESTFRLLNALIFDNKEFYLNILKKEIAKYRFTAESREEINKSLGENQQITYTK
                     GFFLLTFIATHPELQHDFSDETIQNLQISINDFKPKQQVLTEIEYYYRLRSLAVLGNN
                     NEELQNHLNSLVDPILQQKMRVSSLPSSTLETIYNQYLYFGEKEMFIDFMIEHLTDAS
                     SFRLADK"
     gene            1319..1903
                     /locus_tag="J8S10_000643"
     CDS             1319..1903
                     /locus_tag="J8S10_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629254.1"
                     /translation="MDLKQSFYIWLYPDNPMSIMADIFVVSILLYLFYLIFFHNLIGY
                     MILDWKGMFDIERKPFANNQTYTVFESGDWEENEVDVIHEIGLALSGIQDADVLVSMT
                     TDTGYNAYEVFYLMYFIWRDGQEIINGRAEKTINSNTEISFCMGEGEMIVYKDGSANI
                     KTAFGDIETSIKELREYVQNPYNFQYLAGRINLV"
     gene            1914..2159
                     /locus_tag="J8S10_000644"
     CDS             1914..2159
                     /locus_tag="J8S10_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629255.1"
                     /translation="MKKIINQPTNHLIIEGVIFVTMYFTVGNGISNTIIQKNPQYLLF
                     SLYAWIVQMVWVSILMLLFYWIVRVILLLLNKRKKDR"
     gene            2165..2887
                     /locus_tag="J8S10_000645"
     CDS             2165..2887
                     /locus_tag="J8S10_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629256.1"
                     /translation="MKSTKLKVVLLSTAALITLTACGTTNSADNNKDTKSSSTVVTKN
                     SSTSASTTISSMTENNAEKYQKYEDINKGQKPEEVYTDFINTVKNDEDYGNDPLQNKN
                     LTIVLYKPDCPDCQKAESKIMQEIKEGFSYAPTLMHDITINKPAYEYHAVAVDITDGV
                     PEWIQNIPGLADENNQYHTPTVAVVTPKKVNGTLYWDVMGMTTNTTDEMIESTTKYYM
                     DLGAYKLYQQSEPVMDDQSKVK"
     gene            3018..3761
                     /locus_tag="J8S10_000646"
     CDS             3018..3761
                     /locus_tag="J8S10_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629257.1"
                     /translation="MKEISANEAHIPQKNQVGIYKVLHGEGIYKIQLLTGYNNGANGK
                     WLKAKSIRELKTEVEKIRLGLTREEISRLSENSSFVIQKEKEKHLLHRELIIEKYYDV
                     DLPDQLRIIDEFSEKKWKSEIYPSLIQYKASGKPMYNYTGFLNYTQYKYAFRKLKGIK
                     QADIALYEMKKMDRLKLIQELVQNTWNQAIVELEKENGKILTNEYLIVNEIEELIGLF
                     SCENGEVFLKSSPIYSILDSPYQFIQVRR"
     gene            3767..4132
                     /locus_tag="J8S10_000647"
     CDS             3767..4132
                     /locus_tag="J8S10_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629258.1"
                     /translation="MSSLKDDYIQAKQEYEKIQMLKSEKVELFLTQKLAEDHIANLDA
                     KTLEEYDQQFNQTHHNIILLVDQAKRRLEKAEYELLDQGIICLDKGIRRYYSAELKKQ
                     NVDRHALKHEILELIMQRI"
     gene            4148..4678
                     /locus_tag="J8S10_000648"
     CDS             4148..4678
                     /locus_tag="J8S10_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629259.1"
                     /translation="MSQNISAVKQLIEKDLETTVQRLAERIHFANYQTISNWSSRNRN
                     PEEIPMKFFYRIGKEYGVDPIKIFEKTMIYYYHGTPNEVLEHLLEEAEEKSSILEISQ
                     NDKAIQVKCVDPTGKIIVGFDIERKSKIDFITQLTKINNLNILTLRPDHEQLFMSFKK
                     QLKEIQKRYNKVFSNA"
     gene            4840..5208
                     /locus_tag="J8S10_000649"
     CDS             4840..5208
                     /locus_tag="J8S10_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629260.1"
                     /translation="MWNNKLKTGLLLIVISCAMMVGMIIQREQSYFEVSANNVIERCH
                     YGQHFWTGEVRENIDREYVQRIVWDAYSIKDYPKSLTSRLFYSEKDNQKLSNLMMKKV
                     RKLAQNYLEEKEGNSPIDKN"
     gene            5399..5659
                     /locus_tag="J8S10_000650"
     CDS             5399..5659
                     /locus_tag="J8S10_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629261.1"
                     /translation="MAYENLQLVVAEVSGDIYLTKVKDGIMDTNYRRVATDDVLSSST
                     EWFRKNEESAVHFEGIDGNIHSLFYTKDKEKAKKILDILKGR"
     gene            6277..7077
                     /locus_tag="J8S10_000651"
     CDS             6277..7077
                     /locus_tag="J8S10_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629262.1"
                     /translation="MSKDLRELKLRKKQYNQYFSSLLNKHIEEGLDHDFGKDEYCLYC
                     ERYNEKMSEYLQLKKEIQKLEKKVHAWKYKDSRSGYVESQNKPRKKKQAYVLKMVNGE
                     ELIVLAYSEEEVRELVETPVRKKVETINEIDDSQYNSIYIETSHGGYKKLATFLRSSK
                     VGIISKKDISAVTDSFCTLSVPKAYFQYDSKRFERLEKFCRPYTVLKTKKFNKTKRVS
                     IQLPTGQISLGEKDYLIKVGKELIIKVPEHLFKENFEIRETLVWKEEK"
     gene            7114..7296
                     /locus_tag="J8S10_000652"
     CDS             7114..7296
                     /locus_tag="J8S10_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629263.1"
                     /translation="MAVNKILQVLIIDEFGGGEWFDVQSIDFEEEVVVIENIYGEVYS
                     YSLEGENVEDLRLIGE"
     gene            7486..7773
                     /locus_tag="J8S10_000653"
     CDS             7486..7773
                     /locus_tag="J8S10_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629264.1"
                     /translation="MVEVEFGSKEWFEELNSMIKFPEKFTFYYNKRDNIIQVALLETK
                     GRLENTRWSMIKPSALRFHPKDLTAVVAVKEVQDSQEYYEVVKNLKDIWCK"
     gene            7864..8103
                     /locus_tag="J8S10_000654"
     CDS             7864..8103
                     /locus_tag="J8S10_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629265.1"
                     /translation="MKEIEGIKKRNQERLELLNENRNRMFSYYESMRCLNKSRSEIIE
                     SSKYKQLMEERVSLIQEIETESIFPDHSPKVRFYN"
     gene            8231..8560
                     /locus_tag="J8S10_000655"
     CDS             8231..8560
                     /locus_tag="J8S10_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629266.1"
                     /translation="MKLEGSLQNRMMEGSTTNKEIVVGMGATELLYTDRNPYTVIEVK
                     SKNRILVQADGAINKATFPDQEWEYSRNPEGQILELVKTKNGWKVLKEDIHFYIGDRE
                     KYYDPSF"
     gene            8613..9444
                     /locus_tag="J8S10_000656"
                     /pseudo
     CDS             8613..9444
                     /locus_tag="J8S10_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            9459..9776
                     /locus_tag="J8S10_000657"
     CDS             9459..9776
                     /locus_tag="J8S10_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629267.1"
                     /translation="MKREEYKQRLNELLEEDETLTHGSPDEILYMIDNMVIFGGYELG
                     NRSVDHNILEFDDVSWEEILDWGILAVPETKTYISDTMVPFFEELDYKRLPKNENHIL
                     GGN"
     gene            9779..10011
                     /locus_tag="J8S10_000658"
                     /pseudo
     CDS             9779..10011
                     /locus_tag="J8S10_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321015.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(10126..10602)
                     /locus_tag="J8S10_000659"
     CDS             complement(10126..10602)
                     /locus_tag="J8S10_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629268.1"
                     /translation="MTDKTSDLPKLDPKISQVKSKKDGKTKNAVKETSSLLLDIPMSS
                     FDEILDANTDETSVKIASHVGMNSQNDYFYNLLNSLRKLEDKKNQVIASKAPDLTTDL
                     DAEIIQIKQDERSVKSLLKTYFDGFDKELAPYSQAILTKPIQAPHISISLQKKSDD"
     gene            10728..12059
                     /locus_tag="J8S10_000660"
     CDS             10728..12059
                     /locus_tag="J8S10_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HAZ9629269.1"
                     /translation="MVQFTGIAMSVITINPQVLHADGIATYDAQFNCTTEGSGSGTDS
                     DGNDTGSGAVTGDVAKNIEDIYKYMNGEYGLSGASIAGILGNWKQESGIDPRTVEGYY
                     GDGQREVDFIKQFTDGLMGIGYGQWTAGRHTALVDWSKKNNGGSWWTTEAQLDFMFKG
                     DGGFVGILKDYALNASDDVVENAVTFHKNWEISADSESAVIAVRGENAKEIWKYMKSK
                     GMDGAKDESKINKISGGSSTGDGSNNSSSSASGTVEDACATTDDANSGSGSIGKEGKI
                     NGKKGQVIANMTYEEALKKYGKAITLPKFKEPDWSTSPFQGELQGQCTELTWAYMSQL
                     YDGNQPTLGNGGYVWESYKSAGAKVTNKPIVGYAFSALDGWLWAVGSAGHTGVVIAVF
                     DDGSFLCANFNVPPTQAPTRGVSVTLIDGVDGSDNVHFFSGVGKAKFEIEK"
     gene            12084..12611
                     /locus_tag="J8S10_000661"
     CDS             12084..12611
                     /locus_tag="J8S10_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629270.1"
                     /translation="MNSKTKDAIIISLLSGMLLAMLVGILYFNKQNQDIEAEKHSVQI
                     ENELTFFKEVKPNEVDGLQRDLENDIQEMFKGSDRSKFANQSGEEFLRKLFIVTGKPP
                     VTNESSEQEKIEYYKPFTFKLTNFGIKTSSSGLYEALTDFEVQYNGKKVYDTTLTITL
                     NNDKKVTGGAFYAKS"
     gene            12598..13161
                     /locus_tag="J8S10_000662"
     CDS             12598..13161
                     /locus_tag="J8S10_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629271.1"
                     /translation="MQNHEITTAKKAIGILSIILILCCVVLFQKKNAYDNNVKELEDL
                     KSKQIEVVKNNQKVKAMQEAQYKELGNAEIKEQSRKFFNLFYNWNSWEKYTKNMKEIQ
                     KEFPQIVKSSPVDISGTMVGTGNSPISSYTADYYTTNQKGKMVELITQTRNTPTTATT
                     TIWRGVTSIGENQLFYLEDLDSYVRAE"
     gene            13579..14316
                     /locus_tag="J8S10_000663"
     CDS             13579..14316
                     /locus_tag="J8S10_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629272.1"
                     /translation="MADRKLEKLLEETWDPKEFSEFFMENFETDLAVIVKDALREQGY
                     PETANYININFTLYTENRGTWDFWANLANKELSDKSDTGIRNFFESNRDDYMYANNQN
                     KLNFRVEFDETPEEFIERQPPKENVAKVLEDRWNSDEIVSTISEQDGQYEPLVEAVRE
                     ELRLNKFPDVQNIDVSQIEINVNITNRLDYDSWADIALEKYIYSTLKEFIENRMNIMY
                     LQHPQYLNFGVEIATPLEEWKMEQGLD"
     gene            complement(14333..14749)
                     /locus_tag="J8S10_000664"
     CDS             complement(14333..14749)
                     /locus_tag="J8S10_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629273.1"
                     /translation="MNKKRKLSVLITLVSMLAILSGILSIKIFNQINTSANTKNEIVI
                     ENTSNSKEISTTKNKDKSDETTTKNYLIKTVYFDERKTAILKDEEGSELKLPITVSDK
                     FNGTFSLQTAEGSPDNLKVGQTIILGKDEELYSFVK"
     gene            15142..16389
                     /locus_tag="J8S10_000665"
     CDS             15142..16389
                     /locus_tag="J8S10_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629274.1"
                     /translation="MNMKKNSLAMVLFASAVLAGLSVPVTSHADEWTANTPDQIQITT
                     GQSSYAFKKGDTIWSTVEKLKSLGYKTTVAEFAELNNVDLAKGEQRTIPIGRTFNINK
                     DTLTVKEADGEVVSQTVQKDKPDPVENTEQENKKSETTKESEPTANTSDKTETSASSV
                     DGASSSNTNNSTSEKEASQGTSESSTTEADTGTSTNNSQSTSNDANESTSTSSSDQSQ
                     TGSSDETDSSTSPSNPEQPTNVVLGVPFISQGNTMLCEGTSLLEALHYKGVATNQDLM
                     TFVKSMPLSPDNNPNNGFSGEWRHNVDGTYQGMNPAPVVSWGVANGGNVVDISGSSVQ
                     GLKDEIVNGNPVVAWVTYAFEPAQHKSMFWGDAIWNRHVVAVDGFKDGFYHVVDPVFG
                     ASWINAGSFETAYNVSQLAVSVR"
     gene            16659..19049
                     /locus_tag="J8S10_000666"
     CDS             16659..19049
                     /locus_tag="J8S10_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-Gln thioester bond-forming surface protein"
                     /protein_id="HAZ9629275.1"
                     /translation="MKHEKTIILKSKIIYCFATLVMVLSTLIMPFSAIRAEADVTKPT
                     SAKFTETGVKTDGYIRVNMPNHPNEWMISSQFKDSHGNIGYCMDSELPSPTGSGAGSL
                     KYKGAGSDEFYRMFKGGFPSKTAKELGAGNDTEAWYATQLVSWVLAGNFKVSQIVWSH
                     PNHTAAETARVKKAFEKIYDYAKNGKDTPNTEFSITASKTADEGKYHTFTYKTASNKT
                     GNAKLTFTSAKPAGMKIYDADGKEITNNTVKLNSSFTIKVPVTTPSGTLSFKGTANVS
                     TTNPFTFDGRGVYQDAVVMITTSETKDSKSLSAKWTRAVGQVTVKKVDQDGNALKGAE
                     FTLTDNNNAKSVKTTGDDGLATFDLQQGLTYSLEETKVPEGYQGSFKKDGITVNTDGQ
                     EFSYTATNTIKKGKVKVKKVDQDGKPLANAEFTLTDDSSQTQAEKTDENGLASFDIVA
                     NKTYSLEETGVPTGYTGVFKQEGITVKDDGQTFEYTATNTLKKGLVKVHKVDQDGKPL
                     ANAEFTLTDEKGATQVEKTDENGLASFNIVANKTYSLEETGVPVGYTGAFKQEGITVK
                     DDGQTFEYTATNNLKKGVVKVHKVDQDGKPLADAEFTLTDEKGVKEVKKTDATGLATF
                     NIIANKTYNLEETKVPTGYTGAFKQEGITVKDDGQVFEYTAKNTLKKGVIKVHKVDDQ
                     GKALANAEFTLTDDKGVKVVQKTDSNGLATFNIVANKTYKIEETQNPNGYTGKWSKEG
                     ITVADDEQTFEYTVINHLVPETVRTGGIGTSAFLLVFLIAGLSMVLLYYREQHKAK"
     gene            19098..20933
                     /locus_tag="J8S10_000667"
     CDS             19098..20933
                     /locus_tag="J8S10_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HAZ9629276.1"
                     /translation="MKSKKIFSNLMLFGTLLGVGLGASSISSSLGLGGQVAYAQQNYN
                     YQGTGTIHIHKVTNTNGDGNPVSDIDNKGKEIALPNGVKPLEGVEFSYVKLTKDEAKS
                     LGWTDSDTTKGQHIDDAKARLLLNKKYSEVSRMKTDSQGNIDIPIQVNTDDLTDNLYL
                     IVETGTVKGVVEEAYPMIVNVPELNGSDDQYFNYDVHVYPKNYFQLNSAELDKKDEDG
                     KALAGTVFELRKDDGSDQVVGTYKTDSTGKLTVDGLELGDYYFLETDLGTDANKTTYL
                     LDGKKFKFSVKRGETAKVVLDVTNYKRPVITKVIDKETVDTGEDVQYTLKPSIPGNIG
                     NYEKYVVKDVLGAELTYDSSEVIEGMTLDTDYSIERDGQTTNYVFTESGMDKLQKQFD
                     AGDRFFTILMNAHTNSKAKMDTPLKNDVSTIYNNGYEPEDETPVDHAYTIIGDHQFIK
                     TDGDTSKALSGAKFVVKNKIDPNKVTYLKQDPTTKAVTWIADKSKATEFVSGSDGKFQ
                     IEGLQYTYDVDFDKQGNPTITDKKINDYALEEVVAPSGYTPTRNDVPFVVSNDDASSE
                     VTDIKNLKTPETVRTGGIGTVVFLVVAGVAGTGLYVVYKREQHKA"
     gene            21008..21865
                     /locus_tag="J8S10_000668"
     CDS             21008..21865
                     /locus_tag="J8S10_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAZ9629277.1"
                     /translation="MKKKNIKLIILKIGMLLCLGVGLYPVITQAYTYYQTQQTLNSYK
                     EKYDEASEKENEEVFKRYSEVNRKRKDTEQTSVTIPEDNNNIPSNVNLQKDKLGELVG
                     EILIPKINVDLPIYDGVNDFQLSAGAGILTGTDYPTGGIGNHSVISAHSGIPNKKYFT
                     DLELLKLGDKFFIDISGKKLAYQVDRIKTILPTEFEDLLPVAGKDYVTLMTCTPVGDN
                     SHRLLVRGVSIPYQKSIVEKEKKKEDLKVKAQMNWYPIVVVGVLLIIAVIVIIKKIVA
                     KRRGMKNEE"
     gene            21855..22934
                     /locus_tag="J8S10_000669"
     CDS             21855..22934
                     /locus_tag="J8S10_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAZ9629278.1"
                     /translation="MKNKILLFLTLICTLVLTIYPANQLYHQFKTKENVAEIQEKIEK
                     KQTPSKEEVAKKVEQIKSNSGNQGLDNTQKTDGGSFDIGEAEGKVNPYTGDVFSKNQT
                     KDFEPSTYSGAVGYVYIPKINVLELLFLGASQEHLYRGVAQMSATSLPLSGKGHQTVI
                     AGHRGGYTSPQFLYVDQLVAGDHIYIDYLGEKAVYTVFRTDVIRNYGQNSTLTDIPDL
                     DMLTLYTCHPYPQNYDRLLVRSLRDEKAKYITPQVTVGNTAYADAIDSESVSDKTETV
                     TSSNDLFEDVDRANKELDGNNDLNIPEQGSVEMQDRTFAEKASSIFTGITNKHQKMLL
                     VIWTVIGALASLKVLILLIKEFRKA"
     gene            23273..24073
                     /locus_tag="J8S10_000670"
     CDS             23273..24073
                     /locus_tag="J8S10_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629279.1"
                     /translation="MVGISKTALDSLAKLFSSRFDSAEFVEYLSQNESGKTLIETMKK
                     DYLNENDFPTWTNIEDATWDVVCTIYSPWVTIADFVLDKIGGDTYPDAKSLATSDFKT
                     FYGYLIGLIGNGIDLKVTPKQTPEEIEKEKGEVQMAYANDREKVKLLEGKLSEEELGK
                     MVQEINEDSNYFPELKVYQNDEDFFNEMFSNSPWEAVSKTNLGEWNFQDDLVAFSNDG
                     YLRSYSESEYRAELKTYETDILMSYLNLLESGQGELRDKVEELLKEEL"
     gene            24161..24967
                     /locus_tag="J8S10_000671"
     CDS             24161..24967
                     /locus_tag="J8S10_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629280.1"
                     /translation="MRGDQTMSATTDMALEAVIKDNTGNVENVEDFSDIAINLSAWIS
                     AVGEENIEFEIKNMDDLKAKFPFIASKLSQFAEDKSWNELVSFSEKIYDITQEDECVS
                     WEMNNQYKKIDAFVKSRIEGTAFEFEGIDTADNWLNKESFIKSIADDLEKQWSKEDYA
                     EYLKTERDTEVKEKLTEVCLDEHIDPNIVKQEDYEVVIDKVPTDFEEVVKYIVEEALS
                     QYSSDEEVDEETVRTRVWQLVFDDKDYKYLSDQNSVNWSVRLLIDQNDIE"
     gene            25199..26068
                     /locus_tag="J8S10_000672"
     CDS             25199..26068
                     /locus_tag="J8S10_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease"
                     /protein_id="HAZ9629281.1"
                     /translation="MKKKKFSRSLLGILVLVAVGLSGKGYFQNNSTQEHDFQIKSSVQ
                     VGNKADSESKEFLGIRYDPNKYPNNIVNINDGKYTLTKEDHEALSEKGSQTFWVNYAD
                     LDQLGRAGDVEALITYDAINSHSSKNVERPSFKSSVHIAGEYKDGVFDQERDTWVGKD
                     SNNEITQLEGYKGYLYNKSHSLAWSLGGDMEVHNLTLGTRAQNVGKNDQNGGMAYSET
                     IVRDAIYKNKNEKVLYKVDPIYKGNELVPRGSHVEAFSVNDNGKTVNLNVYVFNNQKG
                     ININYQNGTWVRD"
     gene            26088..26435
                     /locus_tag="J8S10_000673"
     CDS             26088..26435
                     /locus_tag="J8S10_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629282.1"
                     /translation="METISINGLDKSVANRIKKGNGYYLLKKGKYSVARELETMSIVY
                     VAKNHFDVEQAIFDPDSEIGKCVELSEKTVSTKGAMIIEREMLDEIRVIIPKDTQMCE
                     DSISDDEPKSERK"
     gene            26448..27710
                     /locus_tag="J8S10_000674"
     CDS             26448..27710
                     /locus_tag="J8S10_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629283.1"
                     /translation="MSEKSIELKEYKRSDGEKYYPVASFSKSVYLVGRALVVGAIGIY
                     ILHWVTKVVQLLVDTLVSILVSLNDVNGTDDLGLKEMFKELLNAFFPNYLSYSYNVQS
                     FFAKLHLVDISILVLEAGTVFFVGYLVTLMFRHHYGEQRPFFDDMESRRLKREALEAM
                     DVKYDPNKIIGDETNNKKRKRNKTQLESDVLSTLKNIKISVHTRRDLSVNEDIREYIV
                     KIPQPKGKKVRETVLRQIQDLGSILTRATSGRAKFGEKEDEVSGDYFIFRASVNIERE
                     RKERVSTKNKETERATSSIAVSNSQFSFPINLFADNSKNIQNQTEKARKYAETQKQSL
                     ELYLSSADVPASLTDMHVGNTSIEYLFTLSRTRKIQLSSMKEEIETYLHISGVIVRIN
                     AGRIQITLPLGENDRIPIDVPSMINSVF"
     gene            27790..29166
                     /locus_tag="J8S10_000675"
     CDS             27790..29166
                     /locus_tag="J8S10_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HAZ9629284.1"
                     /translation="MAMKLLEKVKKRAEKAESILLDKEPNIKLNGKFSVNMLNTKAKD
                     PTDAIFGIKPDGTIAHFCISEMPHMLVAGTTGSGKSVLLNEILVTAMCHSTPDELKIG
                     IVDPKRVEFGRYKKLPFMLADPITDMDEAYDFFEYLVILMHERYKLMEKAGLQNITLY
                     NEYAEKNGLDRFPYVILLVDEYSQLVGTHKEVEGLIVQLGQMARAAGIHVILATQSPR
                     STVVTGIIKANFPSRVCLMVASDLESRIVLDEGGGESLSPKGDMLIKLVDGSMVRAQG
                     AYISNKEIETIFNHLRNTMPEPEYVDYRAIVAETRGEGGEDEDFGGIGKAPVRKSAKR
                     NLNTPLANPSSKEPSIEKKSAFAIKLEKNKEEKANQGAKSLEKLQQEKLEKLEKALSS
                     STSETQSSKGIDNGQSITTKNKPKNSNSNLSVNVVITTDKSEKKQVNGTTSPIMQKMI
                     KAKKQVQK"
     gene            29163..29792
                     /locus_tag="J8S10_000676"
     CDS             29163..29792
                     /locus_tag="J8S10_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629285.1"
                     /translation="MIIISSFLRWLTPYKYTDEIVEKRAKKKVKKTMLTPKEMLDRGI
                     LGVKVLEVNQPFELDNARDRLLRAEVDVAYFYHDKSKHQIAIKFNPKSAWRYQARDDL
                     KRRKLKPMLYPEGKEAFDRTHIVPIGFHGTESDNRLLVGWNSSQNRVQINKFEKKVRK
                     FNDRKIILWFANIQKQPDGTAKWEAVIFDEDGKKVMSEVWHDKAKFVWQ"
     gene            29804..30274
                     /locus_tag="J8S10_000677"
     CDS             29804..30274
                     /locus_tag="J8S10_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629286.1"
                     /translation="MLTNLKLYREGFNEKVSIGESIEYLGKKYIIIRILEIKKLYFSK
                     YNNLAVRVLVQKVGNPSDYRSDYHNYKTESSVIKRYNQSKNDERIFKVGEIIISKYGI
                     AYEIVSIKKFYYEFVDLVVEYSVRLIVPWSKEEINEALKHERKSTFKVLEGEKK"
     gene            30271..30753
                     /locus_tag="J8S10_000678"
     CDS             30271..30753
                     /locus_tag="J8S10_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629287.1"
                     /translation="MKTDLTRQAEKCLWHETNRMGVFGCFEVTIGWDGSERVDYITYS
                     VDNTVRCYEIKVTLADLKSKAKQTFIGDYNYLVVTSDLWEKMQQDDKLMRKYYYQGVY
                     VFNEKYPSIISVKKARKQKVSLGTRSTVLESMVRSMNREVKKLYKVKPFWEIAEVEKG
                     "
     gene            30750..31412
                     /locus_tag="J8S10_000679"
     CDS             30750..31412
                     /locus_tag="J8S10_000679"
                     /inference="COORDINATES: protein motif:HMM:NF019467.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290663.1,RefSeq:WP_002351343.1,
                     RefSeq:WP_010747081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HAZ9629288.1"
                     /translation="MIQTFAKMSRSAWIEKLENDLSVMRLAPKKFKREIAEKEAILSV
                     LNAVELDEPKKSVDVPENVAELLDYYRNSSDVDLLALILTFHDWYYCQNEDTQHDKHD
                     KAVDWLIENPEKFMRAWLDGYDSKKKPLESNEETYLTAEQYDYARKTGDWESGKTFNH
                     RKDQPKISFSDIAAIIEGIYYGQADEEIFSIQDLLEFLNKNKDSFVELTDYEEDTANG
                     KL"
     gene            31399..31767
                     /locus_tag="J8S10_000680"
     CDS             31399..31767
                     /locus_tag="J8S10_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HAZ9629289.1"
                     /translation="MENYDPNMRWGTHTLKVSFQRWDYKGFVTFRKAGNCKGLDVLAL
                     DEDYLYDHPLTDNPIGFGLLPEDDEGNEWFKMILTNDKGDQLFVEDTWSYLSEYIVSI
                     KIIDFVADKEKEIGEGKSNY"
     gene            31848..32294
                     /locus_tag="J8S10_000681"
     CDS             31848..32294
                     /locus_tag="J8S10_000681"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629290.1"
                     /translation="MIVSAVTIYWLGNQQNSLIVDLGELKVGLRMTRWLLLAQTVGLA
                     ILTWICVEKITSNNNQEIVESTNLRITEQAIEKQKDKEKKEIMSIYLSSGASFFHEID
                     SMKLSSQEIIDRWKNMPLGGELIVEDSDGWSAYKKDEIVAITILFE"
     gene            32946..32999
                     /locus_tag="J8S10_000682"
                     /pseudo
     CDS             32946..32999
                     /locus_tag="J8S10_000682"
                     /inference="COORDINATES: protein motif:HMM:NF019230.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            33003..33602
                     /locus_tag="J8S10_000683"
     CDS             33003..33602
                     /locus_tag="J8S10_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HAZ9629291.1"
                     /translation="MREKNKNSSRYLVATVVFVCVLIFLFDFLQIGKSIIGNTLSAKE
                     MVALGGLYEGHLFPNIFISIVSHINLYHLISNLLFLVVLEEALNDQYEWLTLLIVLII
                     SGFLGSLVPFLLQSNIVSMGLSGGIFGWIALFAIAYIHFDSKEHLLLSVFVLLIIGIL
                     LVSTFESGEANVLSHVIGFVCGMILGFILKNVSLIKQKN"
     gene            33618..34094
                     /locus_tag="J8S10_000684"
     CDS             33618..34094
                     /locus_tag="J8S10_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629292.1"
                     /translation="MPKRKEKKIPVFLSVSEMLSLQILLRKKIETIDEEVRNKRAMYE
                     QREALRERIHYFDDIHTKIYEARTNHEDESKLGLAQQRILEWLNTNTDQEPLRVISNL
                     FEFGTKHWFNAVEKDADLQEAFDTLSKDSKSMRDLLITYLNEHEFEQTKTKKKNKE"
     gene            34111..35013
                     /locus_tag="J8S10_000685"
     CDS             34111..35013
                     /locus_tag="J8S10_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629293.1"
                     /translation="MLLTLLGYLCLILAFFGAIAIIIGQFQTNNPIMRNIGIGIVIVT
                     FIVFNATKIFGSNDKQFGISGVNNSYAPDSLGRVVIDGTFENVTSYKNVSLTVKEDGK
                     KASDDVLATIKPSQSQFEVFYTVKENSPVHKLTLVFNVDGEEYYKDVKINKTSTKKII
                     ESAKKEVATEESTTESSSTVEAELPDKIDFDPEKVKSFESVSGSMADRFNTEVFKAIK
                     TVKLDTEKQMINVTLFNSVESMDQDKKVTVARELGKRVIGLYRGTAKPDSDGADLPVH
                     VVYEDGKVFGDSTANEALTIKLAK"
     gene            35086..35277
                     /locus_tag="J8S10_000686"
     CDS             35086..35277
                     /locus_tag="J8S10_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629294.1"
                     /translation="MVVNKEKVRKYVTLKIASVKYLEKRAKEEERARGKKVTVSELLE
                     ELIENDQTIRRAFTNRSIR"
     gene            35441..36028
                     /locus_tag="J8S10_000687"
     CDS             35441..36028
                     /locus_tag="J8S10_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629295.1"
                     /translation="MENNNDIRHFSIGERVTTVSELSKDYRDKEGTIISLNKNRRGVW
                     QYVVDLGDGVTVECKDSQLIRNNGSHSIEKAILVYPKVSSKIMNDWLLGKFGEYNKKE
                     IAEVIGKSYPTVLGYLKKITSKEAKIEDVLTVRELQSLIEYRNKQITNPEYLRKEDGL
                     LKQLEQVNKIRKMQKVAPLSLDTFKKIYLKEIKKD"
     gene            36028..36927
                     /locus_tag="J8S10_000688"
     CDS             36028..36927
                     /locus_tag="J8S10_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HAZ9629296.1"
                     /translation="MWTVTLPFQPVSAPRPSARRNAADETNDVAEKRISTYYDKKYLD
                     YLKKIKSFIEDQDLLDDEFYSIVNDPMGAIMEVDFYYQIPKSYKKVYNIMKTTAPDLD
                     NLVKSAMDGIFNISAIRDSHITGLIAFKYNVANEGKTVVRIKRYSEFEWDTSEGLNGD
                     IWEATFDFKPVATPRPKSKFRGNGIITYYPKEYNDYLENIKNTLKEKDLVNDQLKKVM
                     NAPMGVIAQIDYFYQVRKDKKKLDSLMRTSQPDIDNLVKGTLDGIFNKEIGIKDSRVV
                     GLIAFKYNTFEKSKTNVRLQEMG"
     gene            36927..37841
                     /locus_tag="J8S10_000689"
     CDS             36927..37841
                     /locus_tag="J8S10_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629297.1"
                     /translation="MNNNEKILHVLDSFEIIQEELKKYRDVLEQRYDFVNQQKSNHMD
                     FILNMNDLKKKLVERKEQEKLIKAYFELGEKEVKNAMELNEERRVLDQLLEQLLVMFQ
                     KGRIDEDLIEEGLRKYPSNSGIGIVLKAIDEEEIEAFIPPEDFESAMEYIKYYSQGIT
                     AFREFDPEDVIHDLNNLKEWCESYGVDDSGLDYLISIMEIEEEMPDKPDPTDILELIH
                     EARNPIAYISRGYTVLEYYKPYISAMNHLRRVLREKREYRSVLNATNRLEKAVSELDA
                     YYREHYLQAGGMPRNTKANISRYIKKAE"
     gene            37893..38108
                     /locus_tag="J8S10_000690"
     CDS             37893..38108
                     /locus_tag="J8S10_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629298.1"
                     /translation="MKRDVFELYVLERLEDGMMAQEIIDEIDDMISRFGQLELNDGNK
                     NSVVLKQFWLNNFSYKDFIKEKANTLY"
     gene            38293..38547
                     /locus_tag="J8S10_000691"
     CDS             38293..38547
                     /locus_tag="J8S10_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3034 family protein"
                     /protein_id="HAZ9629299.1"
                     /translation="MKKEELIDIFQIVERANNMGIMFFDRISLKMDLSVAHQEFNLRL
                     KALLNSDDVNFAHDVVGIQNHIDRENKRMGDEFLPRYSSL"
     gene            38726..39769
                     /locus_tag="J8S10_000692"
     CDS             38726..39769
                     /locus_tag="J8S10_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyhydrolase"
                     /protein_id="HAZ9629300.1"
                     /translation="MKKFLVGILFTMGLVLLSPSVSAESSISMYRMYNPNSGEHLYTR
                     SVGERDNLKRYGWHYEGVAWQAPTSGTPVYRLYNRYNGEHFYTVDAGERDKISHTGWT
                     YEGVAFYSYNGANRVPVTRLYNKYVNWHHYTLDQNEKNVISKQGWKIEGTGWYAMPNS
                     VPNPTPAPSTEKVLNVPVVWQGNTMLCEGASLLEGLHYKGVATNQSLTSFVNYMPKAN
                     DNNPYHGYSGEWRHNVNGTYQGMMADPVVKWAKNVGGNAVNITGSGTNGIKNEIRNGN
                     PVVTWITYNYATPEFKQMPWGRAVWNGHVVLVDGFRNGAYHVVDPVFGAKWINASTYE
                     RAFNVTGMAVAVR"
     gene            39942..40166
                     /locus_tag="J8S10_000693"
     CDS             39942..40166
                     /locus_tag="J8S10_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629301.1"
                     /translation="MNQRRRKRLEEISERLSELKDELEVIQEEEYKENIPKNLQGSER
                     YEKAEESVDQLEEAVDGLSDILELIEDIAS"
     gene            40169..40426
                     /locus_tag="J8S10_000694"
     CDS             40169..40426
                     /locus_tag="J8S10_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629302.1"
                     /translation="MINEDFRSENKMIDISLIEKLLFSNKYTAKELATRWQISESAIK
                     AYRQNKGSVGWRDWKGISIGKAEDIMKREGLRSYTTSEKDK"
     gene            40528..40881
                     /locus_tag="J8S10_000695"
     CDS             40528..40881
                     /locus_tag="J8S10_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629303.1"
                     /translation="MISENLSYENNKHLVKENKKVEDYKNMYIEMKKSPLCIQYKNDN
                     WKQVVEFVKPHSIRRVRRGKKKSELVNSGRAVIRVITKDYPVEYGDYILRLSYHAFVV
                     LKEEHFNEFFNLKSK"
     gene            40934..41728
                     /locus_tag="J8S10_000696"
     CDS             40934..41728
                     /locus_tag="J8S10_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629304.1"
                     /translation="MVAKKNTLKEASEKYQDMKRRGLIPKDKKGIWREFVKEVSSDRS
                     GGDFVGRYTAKGYSKRLRITVEYGTNESATELKQRYLDTRREASKKYNDFKSRGLIPK
                     KKKGIWREFFKEEDSNRNKGDFIGRYTAKGYTKNLGIKVEYGTGESSWELRNRYLNTL
                     LEKYKAELLELFDVNDFIEMAEKYGHEEGFMINDIMVIDNFTDLLALAKKARDLRETQ
                     MYLFRNKNGRNRRTESSEIEDYYDAFTHDLGAFVDEISGVMNKYRV"
     gene            41757..42875
                     /locus_tag="J8S10_000697"
     CDS             41757..42875
                     /locus_tag="J8S10_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629305.1"
                     /translation="MGNNSIYTPEMQNKIKRLVGLGWMTRGKLDSFSTIKYLLMDIYR
                     QNKQTGIHFLGYDKPEDAPFFVPSSAYRASTSGSMYNLDLFEEGAKMIEYDFNEAYSR
                     IMRNYPLPSNTYLKAKYNTDQAILRAINRPKVRPYENLRTYMFFLVNFEGTAKEGTYA
                     NPKSQSMFADYGENPKTANEPIWLSEIELTLILDYYDIKEMEVLDSHTFLTKKGLLKE
                     YFERIEPLKTDPDTLKLYKNLRTKVFGAIGQKSLREGETSTFDKYSMYNRAYSSMVAG
                     VFRDRMVRYEQKYVHSAYGLLKIRTDGLYFRSEVPEFEELYKLGVVKKKVHTISKEEV
                     EKALEFKNKGFENKGSFGKSKDEVKGVVIDDDFEFDFD"
     gene            42908..43228
                     /locus_tag="J8S10_000698"
     CDS             42908..43228
                     /locus_tag="J8S10_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629306.1"
                     /translation="MKKKIVEGNVGVIILKDSTDYAKSMALKDEKVARMDKDLVEFLM
                     DDTERLKGDQFLSLMKDKGLNTYGLFDYKKLAIEWVKEGEIFFIEEWEGTENLVLHQY
                     LLKA"
     gene            43483..44172
                     /locus_tag="J8S10_000699"
     CDS             43483..44172
                     /locus_tag="J8S10_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum ABC transporter ATP-binding protein"
                     /protein_id="HAZ9629307.1"
                     /translation="MRTHYIYLEDKIVDEIPAKSREQARKLFIEKYKEINGDSEVPKV
                     VVTVRKRQTKKRSTFHVSPDIYNLIERHRSEDNISISQYIATVIDELISGKYDYAFDF
                     EGEKDYKSVAVFQSDFEKLKNYAGRRNVNFARLLEEFYSEELGVGNEYKRETYAKLSH
                     KLSQALKEVTEVKAELDAKLEEVKKYQTERKNNMKNQVEFDEQKEFEKARKRYNKIMN
                     ELSYEHLTVHE"
     gene            44173..44376
                     /locus_tag="J8S10_000700"
     CDS             44173..44376
                     /locus_tag="J8S10_000700"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629308.1"
                     /translation="MSEGTEKYTIADMVNEVETLLASFFENGHVNDEWRKEEPKRVNA
                     YIARLKRFIDKYKENSDKFSKDK"
     gene            44396..46024
                     /locus_tag="J8S10_000701"
     CDS             44396..46024
                     /locus_tag="J8S10_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629309.1"
                     /translation="MPEIEGIFSPKIGKKQLDFSSFPSVNRDYNLGDEVQILNIDFKE
                     LDFAVAVSNKPKALERVKKIYQENDQNIKNMIKKYRRDNSKVEDVLFNGTAKHDLNVY
                     MALGVALYCNSINQTDILVNIVRNSYQKILKISSETNPYYAMKYLGDNLLNDKKLMHN
                     TEELLSNLAAINFLFKTGSEDYFIDNVLKGAYGTAFYPLYNMKQHKAEQKDNKLEIKK
                     MKELLGIGFVKPNSKVTIASLATTNNDGKIVNGFDDSDIDILSKSYFSLYGDFADLMG
                     IDSYLVNNFEIKGSELNDIVYFVLISLYAIDQNTEYRQIDYLLVFYSLLYQFVLTRLF
                     KNAKEELILNSDYEIAKQIASIRKENKSEVIKLRKELSIASKENGRLESLVKSAKKEE
                     ELLKQEIKELKGIRKELEQLRFENKVLKQLQEQEHRQSLNGKTEEPSLSEMIAYLKHK
                     NILLVGGHVNFQNKLTELLPNIKMFDVSENNGKILKNLNTCDAIFLYTDYLNHGLYYR
                     VMSEISNKDKIFYLDNHVNMNLTIKRIYDLLSLI"
     gene            46075..46446
                     /locus_tag="J8S10_000702"
     CDS             46075..46446
                     /locus_tag="J8S10_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629310.1"
                     /translation="MRELTLSSKELEKKTALLNEIFSADCIIQSLKESSFSKLTDQEK
                     ISYMLSLDNLGTKYDESASSDKLLIELVSSLSSFGKMKRFNVILEIFAWLIPSFIWFF
                     YIFIVESELIAKVSLGLLIPI"
     gene            46531..46731
                     /locus_tag="J8S10_000703"
     CDS             46531..46731
                     /locus_tag="J8S10_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629311.1"
                     /translation="MLKRIAWDKDNKTDIELKEYKYNYFSRCIDRKLLFKKEGLEFSF
                     DEDEFEKLVMDWRKNLLDTVQF"
     gene            46865..48091
                     /locus_tag="J8S10_000704"
     CDS             46865..48091
                     /locus_tag="J8S10_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629312.1"
                     /translation="MIFYMFININEVLKLTTITMTKKIEVYVDGSQEERDSFFDFFWK
                     NSREYVKALNLVYKQLMFEELIKDAIKEMDQGYAEREESIQNRIEKLAYTDPIDQKKL
                     DKAKAELSKLRNEKNKEAREILTQAIGLKSQTRTRDVAKKLDFDFGDFVDSANMKASK
                     DFGNDFIGIVTGQRTPRIYKNRNKYGLLPFRGRDIKIHKDDKFYIYLPKGFRFKVNLG
                     SKPRKARDVASVLQHIMDGDYKLNQSNLIFDGRKLFFNLTISFEKSYNEMEFKKGNEL
                     IVNFADLCSGECLINDKSVMSFGDSQYIRNFKSKILAMKSKEQSRGVFSKGGHGRKRK
                     LDQDRWEAIKKRESNFVKTYNNQCSAKIVKTAIRNKAQIIRIIEPDKAYGEWAYYQLK
                     EQLVNKGKRYGIEVRS"
     gene            48688..49083
                     /locus_tag="J8S10_000705"
                     /pseudo
     CDS             48688..49083
                     /locus_tag="J8S10_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334017.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion protein ImpB"
     gene            49161..49673
                     /locus_tag="J8S10_000706"
     CDS             49161..49673
                     /locus_tag="J8S10_000706"
                     /inference="COORDINATES: protein motif:HMM:NF024954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAZ9629313.1"
                     /translation="METERQIRELEKAMNTTDNRRLYERFLAVKLVLEGHTRKEAGHT
                     IGRDEHTVSHYVKNYCHNGIQGLVSKKQSGRPSRLTDEQEAELVQIVAYHTPEEVGFK
                     SRANWTLAIVCDLILREWSYGYTQKGVADLLHRLGLSWTRPTYTLKKADSKKQQVFLE
                     ETFPSLKKNC"
     gene            49931..51151
                     /locus_tag="J8S10_000707"
                     /pseudo
     CDS             49931..51151
                     /locus_tag="J8S10_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352449.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion protein ImpB"
     gene            51144..51491
                     /locus_tag="J8S10_000708"
     CDS             51144..51491
                     /locus_tag="J8S10_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629314.1"
                     /translation="MIEYNDRGRLKWSGFYLSDHTERINADNVQRANHNLAKEQMTTE
                     EIAKILRTAVIKNRPVCIQKEERNAEGYYPDDVVGKIIGYDELGVFVEEEKVHYDEIR
                     NVSFSELLKWSQI"
     gene            51842..52663
                     /locus_tag="J8S10_000709"
     CDS             51842..52663
                     /locus_tag="J8S10_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HAZ9629315.1"
                     /translation="MGLLVPRANTYTIPLTKRQLIAKRYQRITRAINREFWNSESDTA
                     HSLYVGSYGRGTAISTSDIDIIVELPMAEFDRFKNYLSNGPSKLLQVIKNAFQEILPN
                     SDIRADGQVVKINFHDGIKFEIVPAFNEKDYWGESKGFIYPDSNMGGNWKATNPKKEQ
                     EAMKLKNTKSNNLLYATCKHFRHVRDTEFTSYHLSGIVIDSFVYEAMGNWKFVENNSG
                     GQNISSVSYETALLEYYNSHKVMGGLNLYSPGSNQFVNSDSSIICLEKVLKKIAL"
     gene            52683..53243
                     /locus_tag="J8S10_000710"
     CDS             52683..53243
                     /locus_tag="J8S10_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLATT domain-containing protein"
                     /protein_id="HAZ9629316.1"
                     /translation="MGDEKKRLEVQLREAYGRVTYTYTTHLKQADNIISDNKILRCLQ
                     IGLSALTTGGVLSTIITDNSELTFVAGLCSTISLGLNLYFKNFDLAEEAKNHQIVADK
                     LWLIREEYVSLLTDLNRLSVEDIVKKRDQLMNETHEAYKNAPKTNSKSYESAQKALKS
                     EEEQFFTEEELDKMLPEHLRKKSSKY"
     gene            54132..54899
                     /locus_tag="J8S10_000711"
     CDS             54132..54899
                     /locus_tag="J8S10_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
                     /protein_id="HAZ9629317.1"
                     /translation="MRDRILEVNQEMVNKLTNISGNYEKYDGTLLDNYIFHDTQNIRI
                     GRSKPRAFILIKEKYLNEWNSTYEMVMTDNFEKVLDFRNALLGSDMGNSSLESIEVEN
                     KTENEGEGLIKNVLKIEQKYISEDRSFYRVTSSVGLANFATNLIGNNASESLLVMCLN
                     TKNEVIAYSEVFKGGINQSVAIPREIFQLALLNNSAKIAVSHNHPSGYEFPSENDKSF
                     TTNLKNAGKTIGIELLDHIIVTSKNTSYYSFQENGSL"
     gene            54925..55470
                     /locus_tag="J8S10_000712"
     CDS             54925..55470
                     /locus_tag="J8S10_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629318.1"
                     /translation="MGERTQALITVKYGNSKTKASVSIHYQWGYGRYMLMDVLNQGIY
                     LINKAYDLRDKSREELAKGIFDRSTGVINFVTYESGVSAYDETGFGGRYEPYQETIED
                     VMKFSDNNDGYAHLEMVFDENGFSLDDKTRLRLFDFEGQQIGLNKFCESGKEFATKDF
                     IKGYRLLLENYGINLEEESVK"
     gene            55471..56037
                     /locus_tag="J8S10_000713"
     CDS             55471..56037
                     /locus_tag="J8S10_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629319.1"
                     /translation="MFEKRKDQFPNLEAKSQKVIDGEMIELFQKSYGTIETTASCKYY
                     FQGKRNTFKGFADSDEELAKKIIDWLVSSEHVAREDTVRTTINGEVLTGTRCVCCNHE
                     FVEDEGCYRINEYGDFICQSCHEIEFPTERSWFEYMLQDYEMETENGEVVFCTKEELS
                     KRSDDEIEDWCVWLVGTDDCVAYYTTAE"
     gene            56052..56300
                     /locus_tag="J8S10_000714"
     CDS             56052..56300
                     /locus_tag="J8S10_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629320.1"
                     /translation="MEGMDFIDHEDLIDFGYTWKGMVGISRSLANAFYERNYAVYVLY
                     DDNTESLVDEEYKLDLENVLYGIEKEDLAKYIFSWLGQ"
     gene            56319..56558
                     /locus_tag="J8S10_000715"
     CDS             56319..56558
                     /locus_tag="J8S10_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629321.1"
                     /translation="MTKFKSKGMQWCSYYYVGNDEELLRKAKQKGYPDKMLKQIGYYM
                     PEERIEKESCKVLFDSEQLLVLLTQNKLICQFENN"
     gene            56575..57159
                     /locus_tag="J8S10_000716"
     CDS             56575..57159
                     /locus_tag="J8S10_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629322.1"
                     /translation="MNENKMVLSEYARLRTINWLNGMQSSGAFDGFDEENMDFESLSN
                     EDIRYYFIEWYFTEPDEEVEDEPELILERQRILFSEQDSKRLYGLYDLQLKGLKAQYV
                     ADSYDDMVEQGADRVVTYSEDDEEEWENYSDDEICFNDGYMPIEITEEEYDKVSDSDE
                     IGMCTVVSGLDIDVQRVEVAYQKMKERIKSKVES"
     gene            57266..57547
                     /locus_tag="J8S10_000717"
     CDS             57266..57547
                     /locus_tag="J8S10_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HAZ9629323.1"
                     /translation="MKVKNPKEKSRIQVGIDKDLKENAEMILEELGLNPTTAITILYK
                     QVVARGEFPVEIKLSEEEKQGIRLQQLTMDMPVDVLDTDEKLEEWFNEA"
     gene            57537..57878
                     /locus_tag="J8S10_000718"
     CDS             57537..57878
                     /locus_tag="J8S10_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAZ9629324.1"
                     /translation="MKPNEIVTVYVAFTDKNGGKRRPILVVSDKEDRVEFFGITSQYE
                     NKSDQIKRVYFPIAEWEKVGLKKQSWIDVGSLKAIPKSRENISFKKVGMLSAIDTKKL
                     NRFIERLQRKV"
BASE COUNT        22096 a         7773 c        11682 g        16833 t
ORIGIN      
        1 cttatctgct aacctgaatg aactagcatc ggtaagatgt tcgatcataa aatctatgaa
       61 catctctttt tcaccaaaat ataaatattg attatatatt gtttctaatg ttgaagatgg
      121 tagcgaagaa actctcattt tttgctggag tataggatca actagactat ttaagtgatt
      181 ttgtaattct tcattgttgt ttcctagaac tgcaagggaa cgtaaacggt agtaatattc
      241 tatttctgtt agtacttgtt gtttcggttt aaaatcattt attgatattt gtaaattttg
      301 aattgtctcg tctgaaaaat catgttgtaa ttctggatgg gtagctataa aagtaagtaa
      361 aaagaaccct tttgtatacg tgatctgttg attttcacca agtgatttat taatttcctc
      421 tcttgattca gctgtgaacc tatactttgc aatttctttt tttagaatat ttaaatagaa
      481 ttctttatta tcaaaaatta gggcattaag tagtctgaaa gtactttccc tatttctatc
      541 tgcttcctca tttccataag ataattgaaa aacaaactta aaggctgtct tacataggtt
      601 ttctttggct ttttcgctta gtttatttag atagctattt tttagtgcag agtgaaattc
      661 ttcaggtgta acagacatag catgtatgcg acttgcatat tgtataattt cgatcgttac
      721 tttttttcct aatattggat tttttaggaa tataatttca taggacttcc gtataacatc
      781 ctgacaagtt tcttttgtta tatctcttaa ttcccaagta ttaccgttgt aagtgactac
      841 aggatgagct gaataatttc tttgatcctt aatatatttt aaatcctcat attcatagct
      901 atcaattagc tcagttgaac tataagcttt ttctagtagt tccatttccc attttggaga
      961 gtttggatca ctttttctta gtctagctat atcttctaaa attttcttag aagtattatc
     1021 ctcgtaaata tttgctaaat cagataattt atcaattaaa tctaaaataa gcgcactgta
     1081 attgacagct attgcagaac gataatttcc ctgataaaaa ctacttctaa cttcttctaa
     1141 taatggaata attctaggat ttttaacttt ttttatttca tcatctaata taaacatata
     1201 aatctccttt ttttatttgt atgacaagtt taccataaaa aaaaattaaa aagcgagaca
     1261 tatttatgtt gttgtgttat cataataaca taaatatgta gagtgagatg atgaaaaaat
     1321 ggatttgaaa caatcgtttt acatctggtt atatcctgat aatcctatgt caataatggc
     1381 tgatattttt gtagttagca tcttattgta tttattttat ctaattttct ttcacaattt
     1441 aatcgggtac atgattcttg attggaaagg aatgttcgat atagaaagaa aaccatttgc
     1501 taacaatcaa acctataccg tcttcgaaag tggagattgg gaagaaaatg aagttgatgt
     1561 gatccatgaa attggattag ctttatcagg aatacaagat gctgatgttt tggtatcaat
     1621 gacaacggat actggataca acgcttatga ggtattttat cttatgtatt ttatatggcg
     1681 tgatggtcaa gaaattatca atggtcgtgc tgaaaaaaca atcaattcta atactgaaat
     1741 ttctttttgt atgggtgaag gggaaatgat tgtatataaa gatgggtcag caaacattaa
     1801 aacagccttt ggtgatattg aaacaagtat taaggaactt agggaatatg tgcagaaccc
     1861 atataatttt caatatttag caggaagaat aaatttagtt taggagtaaa aatatgaaaa
     1921 aaattataaa tcaaccaaca aatcacttga taattgaagg tgttattttc gtaacaatgt
     1981 attttactgt aggaaatggc atctcaaata caatcattca aaaaaatcca caatacctat
     2041 tatttagtct ttatgcttgg attgtacaaa tggtttgggt ttccatattg atgctgttgt
     2101 tttattggat agtacgggtt attcttttat tgttaaacaa aagaaaaaag gataggtgaa
     2161 taaaatgaaa tcaactaaat tgaaggttgt attgttatcg acagcagcat taataactct
     2221 tacagcatgt ggtacaacta atagtgctga taataacaaa gacacaaagt ctagtagtac
     2281 ggtggttact aaaaacagct ctacatcggc atcaacaaca atttcttcaa tgactgaaaa
     2341 taatgctgaa aagtatcaaa aatacgaaga cattaataaa ggtcaaaagc cggaagaagt
     2401 ttataccgac tttattaata cagtaaaaaa tgatgaagat tatgggaatg atccattgca
     2461 aaataaaaat ctgactatcg ttctttacaa acctgattgt ccagattgtc aaaaagcaga
     2521 atcaaaaatc atgcaagaaa taaaagaagg atttagttat gctccaacat taatgcatga
     2581 tattaccata aataaaccag cttacgagta tcacgcagtt gctgtagata ttactgatgg
     2641 tgtacctgag tggatacaaa acattcctgg tctggctgat gagaacaatc aatatcatac
     2701 gccaacagtt gcagtagtaa caccaaagaa agttaatggc acactatact gggatgtaat
     2761 gggaatgaca acaaatacaa ctgatgaaat gattgaaagt acaactaaat attatatgga
     2821 tttgggagca tataaattat atcaacagtc agaacctgtt atggacgatc aatccaaagt
     2881 taaatagttc tttagggcgt aagccctatt tttttaaaat taagtgataa caaataaatg
     2941 atttctgaaa caaacgttct tactcaacta ctcgaaacac acaagctaat taactagatt
     3001 ataaaggaga atgcgtaatg aaagaaatca gtgcaaatga agctcatatt ccgcaaaaga
     3061 atcaggttgg tatatataag gtgcttcatg gtgaaggaat ttataaaata cagttactta
     3121 ccggttacaa taacggtgca aatgggaagt ggttaaaggc aaaaagtatt cgtgaactta
     3181 aaactgaagt agaaaaaata agacttgggt taacaaggga agaaataagt agactgagtg
     3241 aaaattcttc ttttgtaatc caaaaagaaa aggagaaaca tctacttcat cgggaactaa
     3301 taattgaaaa atactacgat gttgatttac ctgatcagtt aagaattatt gacgaatttt
     3361 cagagaaaaa gtggaaatct gaaatatacc caagcttaat tcaatacaag gcatcaggaa
     3421 agcccatgta taactacaca ggctttttaa actacacaca atataaatat gcctttcgca
     3481 aattaaaagg cattaaacaa gctgacattg ccctgtatga gatgaaaaaa atggatagat
     3541 tgaaattgat tcaagagtta gtgcaaaata catggaatca agcgattgtc gaactagaaa
     3601 aagaaaatgg gaaaatttta actaatgaat atctgatcgt aaatgaaatt gaagaattaa
     3661 ttggtttatt ttcatgtgaa aatggtgaag tcttcttgaa gtcatcacca atctattcaa
     3721 ttttggacag tccgtatcag tttatacagg taaggagatg agttacatgt ctagcttgaa
     3781 agatgactat atccaagcaa aacaagagta tgaaaaaata cagatgttaa aatctgagaa
     3841 agtcgaatta tttttaacac aaaaattagc agaggatcat attgctaact tagatgctaa
     3901 aactttagag gaatatgatc agcagtttaa tcagacacat cacaatatca ttttgcttgt
     3961 tgatcaggca aagagaagac ttgaaaaagc ggaatatgaa ctattagatc aaggaattat
     4021 atgcttggat aaagggattc gaagatatta tagtgcagag ttaaaaaagc aaaatgtaga
     4081 cagacatgcg ttaaaacatg aaatcttaga attgataatg caacgaattt gaagggatag
     4141 aaagtaaatg tcacaaaaca ttagtgctgt aaaacaatta atagaaaaag atttagagac
     4201 gacagttcag aggttagccg aacgaatcca ttttgcaaat tatcaaacca tctctaattg
     4261 gtcaagcagg aacagaaatc cggaagaaat tccaatgaaa tttttttatc gaatcggaaa
     4321 agaatatggt gttgatccga taaaaatttt cgaaaagacc atgatttatt actatcatgg
     4381 aacacctaac gaagtgttgg aacatctttt ggaagaagca gaagaaaaat catcaatatt
     4441 agagatatca caaaatgaca aagctattca agtgaaatgt gttgatccaa caggaaagat
     4501 tattgttgga tttgatattg aaagaaaatc taaaatagat tttattactc aattaacaaa
     4561 gataaataat ttaaatattt taacacttag accagatcat gaacagttgt ttatgagttt
     4621 taaaaaacaa ttgaaagaaa tacaaaaaag atataacaag gtgttttcta atgcgtgaaa
     4681 agctaaaaga aatcagagtg ttttggataa ttaacaaaga atttattatc ttgtatacac
     4741 ttggatttat cagcatgatc ttgttttggt ggttatattt aaaaaagtaa tttaaaagtg
     4801 tcaaggagat ttttatccag agaaggatgt ggaatttgca tgtggaataa taaattaaaa
     4861 acaggcttgt tattaatagt tatttcctgc gctatgatgg ttggcatgat aatacaaagg
     4921 gaacaatctt attttgaagt ttctgctaac aatgtaatag aaagatgcca ttatggtcaa
     4981 catttttgga ctggggaagt cagagaaaat atagatcgtg agtatgttca aagaatcgtt
     5041 tgggatgcat attctatcaa agattatcct aaaagtttaa cgagtagatt attttacagc
     5101 gaaaaagata atcaaaaact ctcgaatttg atgatgaaaa aagtaaggaa acttgcacaa
     5161 aactatttgg aagaaaaaga aggtaatagt ccaattgaca aaaattgatg acactgcaaa
     5221 aaaatataga gttcgaatta gcttttttcg gagcattgtt ttttaggtga actatatttc
     5281 atcactaaaa tcagagataa ctaacttgaa acatggtcag atgtgttact tgaagtctct
     5341 gaataatcaa tgttatctag tagaattaag caactaaaaa agaaagaagt aagaaaatat
     5401 ggcatacgaa aatttacaat tagtagtcgc agaagttagt ggggatatat accttacaaa
     5461 agtaaaagat ggaattatgg acacgaatta taggagagtt gctacagatg atgtgctaag
     5521 ctcatcgaca gaatggtttc gaaaaaatga agaatctgct gttcactttg aaggaattga
     5581 tggaaacatt catagtttgt tctatacaaa agacaaagaa aaagcaaaaa aaattcttga
     5641 tattttgaaa ggaaggtagt taattaacca atgatataag agaatgtgag accaagtaaa
     5701 tacttggtct ctataatttt agccactagt caattaaata gctaaacaat tttaataata
     5761 ataaaatatg actgcttcat aattaagaag tgcagaattt ttctaagaac gatatttcct
     5821 tgttgaaatg agtattgcta acaatttgat cacgaacagc atcgttacaa atgttgtatc
     5881 aatatttgat agattacata ttctattaaa aaagaaaaga aaattattga tattatacac
     5941 attagtgtgt ataataaaag agagggagtg attagaactt tgagcaattc actaattgtt
     6001 taataataga acgattccta agaagttcat tgttcattgg caaattgctt tatcagattg
     6061 aaagttggcg aataaggttt gtagaataac accttttcaa gcaaagcgat ttttgaaagc
     6121 tatgaaattt gtttaataaa aaaattcacc agataatctg atagagacta acccaattac
     6181 taacagttgt aattggtgtt agcttacaaa ttaattattg tgtttagtca attacaaatt
     6241 gtgaaacggc actaataatt ggaaaggaaa aatgaaatgt ctaaagattt acgagagctt
     6301 aaattgcgaa aaaagcaata taatcaatat ttttctagtt tgttgaataa acatattgaa
     6361 gaaggacttg atcatgattt tggaaaagat gaatattgtt tatattgcga acgttacaat
     6421 gaaaaaatgt ctgaatatct acagctgaaa aaagagatac agaaattaga gaaaaaagta
     6481 catgcttgga agtataaaga ttccaggtct ggttatgttg aatctcaaaa taagccaaga
     6541 aaaaagaagc aagcgtatgt tctaaagatg gtaaatgggg aagagttaat tgtattagcg
     6601 tacagtgaag aagaggttcg agaactcgtt gaaacacctg tcaggaaaaa ggttgaaaca
     6661 ataaatgaga tagacgacag ccaatacaat agcatctata ttgaaacaag tcatggtgga
     6721 tataagaaat tagcaacttt ccttagaagt tctaaagttg ggataatttc taaaaaagac
     6781 ataagtgctg ttaccgatag tttttgtact ttatctgttc ctaaagctta tttccaatac
     6841 gatagtaaaa gatttgaacg cttagagaaa ttctgtagac cgtatactgt attgaaaact
     6901 aaaaaattta ataaaactaa aagagtttcg atacagttac cgactggtca aatctcatta
     6961 ggtgaaaaag actatctgat aaaagtagga aaagagttaa ttataaaagt accggaacac
     7021 ttatttaaag aaaattttga gatacgtgaa accttggtat ggaaagaaga aaaatagttt
     7081 ggaagacata gaatggtata aggggaaatt gaaatggcag taaataaaat attgcaggta
     7141 ttaatcatag acgaatttgg cggaggagaa tggtttgatg tgcagtccat agactttgaa
     7201 gaagaagtcg tagttataga aaatatttac ggcgaagtat actcatattc gcttgaaggt
     7261 gagaatgttg aggatctacg gttgattggt gagtagaaaa aagcagaaat atcaaaatgg
     7321 agataaaaat taatagcatg taaagatagt catgcttaca tgctttatcc aaaatggtat
     7381 gcagacaaaa atatagctga aataaacgat tatctaacta gtataaagga acgcaatgca
     7441 attaattaac aatagacgaa aaatgaaatt aaaggagata ggaaaatggt agaagttgaa
     7501 tttggatcaa aagaatggtt tgaagagtta aactcaatga ttaagttccc agaaaagttt
     7561 actttttact acaataaaag agacaatatc attcaagtag ctttacttga aactaaggga
     7621 agattagaaa atactcgatg gagtatgata aaaccatcgg cacttagatt tcatcctaaa
     7681 gacttgacag cggttgtagc ggtaaaagag gttcaagact cacaagaata ttatgaagta
     7741 gtaaaaaatc tgaaggatat ttggtgtaaa taattctaaa ttgaccagtt atttggtcaa
     7801 aaatagtatg tgattatttc atccaatgtg gcatcataat tggtatggaa ggggataaat
     7861 tatttgaaag aaatagaagg tattaagaaa agaaatcagg aaagattgga actgttaaat
     7921 gaaaatagaa atagaatgtt tagttattat gaatctatga ggtgtttaaa taaatctaga
     7981 agtgaaatta tagaatcatc aaagtataaa caattgatgg aagagagagt ttctctcatc
     8041 caagaaatag aaacagagtc tatttttcca gatcattctc ctaaagtccg attttataat
     8101 taaacattaa caaatgaaac gatgctaaat aggcatcgtt ttttatctat ttataaaatt
     8161 aatttattta caaaatgtgt atcggtatgt atggtgaatt tgtagataag ttgagaaagg
     8221 gtgatcttaa atgaaattag aaggtagctt acaaaataga atgatggaag gcagtacaac
     8281 aaacaaggag attgtagttg gaatgggagc aaccgagctt ctatataccg acagaaatcc
     8341 ttatacagta attgaagtaa aaagcaaaaa cagaattttg gttcaagcgg atggagcaat
     8401 caataaagct acttttccag atcaagagtg ggaatatagc agaaatcctg aaggtcaaat
     8461 attggagtta gttaagacaa aaaatggatg gaaagtgctt aaagaagata ttcattttta
     8521 tataggtgat agagaaaaat actacgatcc tagtttttaa acaacctgaa gatgagcgag
     8581 gttttatcct cgctcagaaa ggagtatgga ggatgttcag tcaagaagaa atcatcagca
     8641 aatcgcaacc ggataaaaat ggaactataa tcatgaagaa aaaaatccct tgctatcgtt
     8701 gtagcggatc aggtcagtac aagtttatgt ctatggggaa aattacctat ggcacatgtt
     8761 ttaagtgcga tggtgatgga tttcttgttg taactgaaaa atcctttacg ccagaatata
     8821 gaactaagct aaatgtttta aataaaaaaa gagctgatcg aaaaataagg atcgcaagag
     8881 agaaagaatc tcagaaaaat tttgatcgtt atggctttga aaagggttat atttacgtgg
     8941 ttatagagaa aaatagctat acgatcaaag atgaactgca tcatcaagga gctacttatg
     9001 atcctttatt aggttggttt ttttaaggaa aaacaagaac aatacaaaac tcaaaaagtt
     9061 tttgtagaag aattttctgt aatcaatgat gaaggaatta ttgagttgaa gctagaagaa
     9121 tacagcaaaa gacaacagga gattttaagt gcgaagcgta gagaagaggg tgagtttatt
     9181 ggtacaatcg ctcaacgatt ggaattggat ttgaaactta ccaataccgt caccatagat
     9241 acacaatggg gcaatgttta cctgcattta tttgaagatc aaaaccataa ttcattgatt
     9301 tggaagacaa ataaatttct ttattatgat gaatgggatg ttggagaaat aagaaaagtt
     9361 aaggcgacaa taaaagcgca tgactactac agagatacca agcagacttg gattaaaaat
     9421 gttaaaattc aaaaaaatga gtaagaaggg ataaaagtat gaaaagagaa gaatacaaac
     9481 aaagattaaa cgaactgctt gaagaggacg aaacattaac tcatggttcg ccggatgaaa
     9541 ttctatacat gattgataat atggtaattt ttggtggata tgaacttggt aataggtcag
     9601 ttgatcataa tattttagaa tttgatgatg tatcatggga agaaattctt gattggggaa
     9661 ttttggcagt acctgaaact aaaacctata ttagtgacac tatggttcct ttttttgagg
     9721 aattggatta taaaagactt cccaaaaatg aaaatcatat actgggagga aactaacaat
     9781 gttaagtgac ttacttattt tactgatcta tctaggtgga actgaaatta ttgcgtattt
     9841 tttgcttgta attggtgaat atggtatttc cagtgcaatc actcaaaggt ttagattacc
     9901 agtaagtgaa ctaaaaaaat gatgagatta tcagcatatc ttttaatgtt tttgaatgtg
     9961 gtcatgttaa tctttgtagt aatcggtgtg actttcaatt taacggaata gagggaaatc
    10021 tataatggaa aaaagagaaa agaatgaaca tattttttga gtcaatattg ttgatggttt
    10081 ttgcgatcag cgcttaccag aaatctaaaa aagagtaatg actgtttagt catcactctt
    10141 tttttgtagg gaaattgaaa tatgtggagc ttgtattggt ttagttagga ttgcttggct
    10201 ataaggagct agttctttat caaaaccatc aaagtaggtt ttcagtagcg atttaactga
    10261 tcgctcatct tgtttgattt ggataatttc agcatccaaa tcggttgtga ggtcaggagc
    10321 ttttgaagcg attacctgat tttttttatc ttccaacttt cttaggctgt ttaacaagtt
    10381 gtaaaaataa tcattttgac tgttcattcc aacgtgagat gcaattttaa cagaagtttc
    10441 atccgtattg gcatcaagta tttcatcaaa agaactcatt ggaatatcaa gtagtaacga
    10501 ggatgtttcc tttacagcat ttttagtttt tccatctttt ttgctcttaa cttgagatat
    10561 ttttggatct agtttaggta aatcacttgt tttatcagtc atttattagc ttttcctttc
    10621 tattaattta tgttattata ttatcataat aacataaaaa agaacacttt ttgggggcgt
    10681 agttattgaa aaaatctaag agaaagattg ccacgttgct tacgttaatg gtgcagttta
    10741 cagggattgc aatgagtgta atcacaataa atccgcaagt gttacatgct gatgggatag
    10801 ctacttatga tgcacaattt aactgtacta ctgaaggtag tgggtcagga acagatagcg
    10861 atggaaacga tactggaagt ggcgctgtaa caggtgatgt agccaaaaat attgaagata
    10921 tttacaaata catgaatgga gaatatggct tatcaggtgc tagtattgca ggtattttag
    10981 gtaactggaa acaagaatca ggtattgatc ctcgaacagt agaagggtat tacggcgatg
    11041 ggcagagaga agttgacttc atcaaacaat ttactgatgg tctaatgggt attggctatg
    11101 gtcaatggac agccgggcga catacagcat tagttgattg gtctaagaaa aataatggcg
    11161 gttcttggtg gactacagaa gcccaattgg actttatgtt caaaggtgat gggggattcg
    11221 taggaatatt aaaagattat gctttaaatg cttctgatga tgtagtagaa aatgcagtaa
    11281 cttttcataa aaactgggaa atttcagctg attccgaatc agctgtaata gctgtacgtg
    11341 gtgaaaatgc aaaagaaatc tggaagtaca tgaaaagcaa gggtatggac ggtgcaaaag
    11401 atgaaagtaa gatcaataaa atatccggag gttcaagtac cggagatgga tcgaataatt
    11461 catcaagttc agcatcagga acagtagaag atgcctgtgc aactacggat gatgctaatt
    11521 ctggttctgg atcaattggg aaagaaggaa aaattaacgg taaaaaaggt caagtaatag
    11581 caaatatgac ttatgaagaa gcattaaaaa aatatgggaa agcaatcacg ctaccaaaat
    11641 ttaaagaacc agactggtca acatcacctt ttcaaggtga attacaagga caatgtactg
    11701 aattaacatg ggcttatatg agtcaattat atgatggaaa tcaaccaact ttgggaaatg
    11761 gcggttacgt ttgggaaagc tacaaatcgg caggagcaaa ggtgacgaac aaaccaattg
    11821 taggttatgc gtttagtgct ttagatggat ggttatgggc tgttggatca gcaggacata
    11881 caggtgtagt tatagcggtg tttgacgatg gatcattttt gtgcgctaat ttcaatgttc
    11941 cacctaccca agcaccaaca agaggtgttt cagtaacttt gattgatggt gtggatgggt
    12001 cagataatgt gcatttcttt agcggtgtag gcaaagctaa atttgaaatt gaaaaataaa
    12061 aatttgaatg gagggcgaca gagatgaata gtaaaacgaa agatgcaatt atcatttctt
    12121 tgctttctgg tatgctatta gcaatgcttg ttggaattct atatttcaat aagcagaatc
    12181 aagacataga agctgaaaag cacagtgtgc aaattgaaaa tgaattgacc ttctttaaag
    12241 aggttaaacc aaatgaagtg gatggattgc aaagagattt agaaaatgat attcaagaga
    12301 tgtttaaagg atcagaccga agcaaatttg cgaatcagtc aggtgaagaa tttttgcgaa
    12361 agttatttat tgtgacaggt aagccaccag ttactaacga gagtagcgag caagaaaaaa
    12421 tagaatacta taaacctttt acttttaagc taacaaactt tggaattaag acatctagta
    12481 gtgggttgta tgaagcattg actgatttcg aagttcaata caacggaaaa aaagtgtatg
    12541 ataccacatt aaccatcaca ctaaataatg ataagaaagt gactgggggt gctttttatg
    12601 caaaatcatg aaattactac tgctaaaaag gcgatcggaa tactttccat aattttgatc
    12661 ctttgttgtg tggtactatt tcaaaagaaa aatgcttatg ataataatgt caaagaattg
    12721 gaagacctta aaagtaaaca aatcgaagta gtcaagaata accagaaagt gaaagctatg
    12781 caagaagccc aatacaaaga attgggaaat gctgaaatca aggaacaaag taggaaattc
    12841 tttaatttat tttacaactg gaattcatgg gaaaaatata cgaagaatat gaaggaaata
    12901 caaaaagaat ttcctcagat agtaaagtct agtcctgttg atatctctgg cacaatggta
    12961 ggtactggta atagtccaat atctagctat actgctgatt actatacaac aaatcaaaaa
    13021 ggtaaaatgg ttgaattgat tacacagaca agaaatactc caacaacagc aacaacaaca
    13081 atttggcgtg gagtaacaag cataggagaa aatcaattgt tttacttgga ggatttagat
    13141 agctatgtaa gagcagagta aaataaaaaa agagctaacg gtaccaacgt tagctctttg
    13201 tgctgacgat gataacaaaa cctaccgaaa aaggattgtt tcatcacaaa cacaaacaga
    13261 aaagaattga taaaaaaccc gaacctcaga atttttatta atcaattcat tttgattata
    13321 ataaattgag ctgaacatta caatacgtat atgttgtaaa acgtaaaaaa agtcaaaagt
    13381 aaatactttc ttaaaaagtc aaataaaact attaaagaca atatatatgg tttatttgac
    13441 ataagaaaat ggtctagatg ataattagaa tatagaattg tagacttaaa taaatcataa
    13501 aaaaccttct atgataagtt atagctctta attttaagca gttttagata taagaaagta
    13561 aagtggggga gaataataat ggcagatcgt aaattagaaa agttattaga agaaacgtgg
    13621 gatccaaaag aatttagtga attttttatg gagaattttg aaactgactt agcggtgatt
    13681 gttaaagatg ctcttagaga gcaagggtat cctgaaactg caaattatat aaacattaat
    13741 tttactttgt atactgaaaa tagaggaact tgggattttt gggctaactt agcaaataag
    13801 gagttaagtg ataaatcaga tacaggaatt cgtaactttt ttgaatcaaa cagagatgat
    13861 tatatgtacg ctaacaatca aaataaattg aactttagag tagagtttga tgaaacacct
    13921 gaagaattta tagaaagaca accgcctaaa gaaaatgtag caaaggtatt ggaagatcgt
    13981 tggaattcag atgaaatagt ttcaacaatt agcgaacaag acggacaata tgaaccgcta
    14041 gtagaagcgg ttagagaaga gctaagactg aataagtttc ctgatgttca aaatattgat
    14101 gtttctcaaa ttgaaataaa cgtcaatatc accaatagac ttgattatga tagttgggca
    14161 gatatagcat tagaaaaata tatttactca acgttaaaag agtttatcga aaatagaatg
    14221 aatatcatgt atctacagca tccacagtat ttaaactttg gtgttgaaat agctacacct
    14281 cttgaagaat ggaaaatgga gcaagggctt gactagcctt tgctccattt ttttatttta
    14341 caaatgaata cagttcttcg tctttaccaa gaatgattgt ttgcccaact ttgagattat
    14401 caggtgatcc ttcagcggtt tgtaaggaga acgttccatt gaacttatcg gataccgtta
    14461 taggtagctt taattctgat ccttcctcat ctttgagaat tgctgttttc cgttcatcaa
    14521 aataaacagt ctttattaga taatttttag tagtggtttc atcagatttg tctttgtttt
    14581 tagtagtact aatttcttta gaattagatg tattttctat gactatttcg tttttggtat
    14641 ttgcgcttgt atttatttga ttgaaaattt taatcgacaa gatcccacta agaatagcca
    14701 acatagaaac aagtgtaatt aatactgata atttcctttt tttgttcatt tcttcttaac
    14761 ttcctttttt gttttgatta gttagatatt ccttatctaa taagcctttt taggctatta
    14821 aatgaagata aaccccaaaa aattattgca ataatgatag tgcaatggta ctattattat
    14881 aaaataaatt ttgcgaaagg ggtaggtcta aatcgcaaat aaaaagaaat tgaacctaga
    14941 caaatacaac ttgtataccg caagggaagc aagtctaatt ttgggtaaag gtagaaatta
    15001 tgttacaaac ataatcaact attatccaaa tcgtttgcct aaaggttcgt tcaagaaagt
    15061 gggtgacaaa acctatatta taacggaaga aggaatagaa gcattgcgat cacaaacaga
    15121 aaataaaaac aaaaagaagg aatgaatatg aagaaaaatt cgcttgctat ggttttattt
    15181 gcatcagctg tacttgcggg gttatcagta ccagtaacct cacatgctga tgaatggact
    15241 gcaaacacac cggatcaaat ccaaattaca acaggacaat caagttatgc gttcaaaaaa
    15301 ggagatacta tttggtcaac tgtagagaag cttaaaagct taggttacaa gactactgtt
    15361 gctgagtttg ccgaattgaa caatgttgat ttggcaaaag gagaacaacg gactatcccg
    15421 attggacgaa ctttcaacat caataaagat acattaacag ttaaggaagc agatggcgaa
    15481 gtagttagtc aaactgttca aaaagataaa cctgatcctg ttgaaaatac ggagcaagag
    15541 aacaaaaaat ccgagactac aaaagaatcg gaaccaacag caaacacttc tgataagaca
    15601 gaaacaagtg cttcaagtgt tgatggagca agttcatcta atacaaataa ttctacaagt
    15661 gagaaagaag catcacaggg aacaagtgaa agtagcacta cggaagctga tactggaaca
    15721 tcaacaaata actcacaatc aacatcaaat gatgcaaatg aatcaaccag tacatcttct
    15781 agtgatcaat cacaaacagg ttcaagtgat gaaactgaca gttctacttc accaagtaac
    15841 cccgaacaac caactaatgt tgtgctaggc gttccattta ttagtcaagg taacacaatg
    15901 ctttgcgaag gaacatcttt gctagaagcg ttacattata aaggtgttgc aacaaatcaa
    15961 gatttaatga cttttgttaa atcaatgcca ctatctcctg ataataatcc aaataatggt
    16021 ttttctggtg aatggagaca caatgtggat ggaacttatc aaggtatgaa tccggctcct
    16081 gtagtttcat ggggtgttgc taatggcgga aatgttgtag atatttctgg ttcatcggta
    16141 caaggattaa aagatgagat tgtaaatgga aatcctgtag tagcgtgggt aacttatgcc
    16201 tttgaacctg ctcaacataa atcaatgttt tggggcgatg ctatttggaa tcgacatgta
    16261 gtagccgttg atggatttaa agacggtttt taccatgttg tcgatcctgt gtttggggca
    16321 agttggatta atgcaggatc atttgaaaca gcatataacg tatctcaatt agcggtttcg
    16381 gtacgttaat aaaagagatc gtttatatac taagtagtta agtatagtct ttatttgtcc
    16441 ttgcttaact acttagaaaa cttgttgctc atggttggta gaactaaaag gggtgatgct
    16501 atgagtacta gagcgttgaa acagcttgct ttcaacgaaa aaagtgatta ataggtgtgg
    16561 tgattttaac ttaggaatgg gcgcgaaggt cattaccaca ccgacatatc gtggctcatt
    16621 ttcttcgcct aactggtata aagaaggagt aacgagagat gaagcatgaa aaaacgataa
    16681 ttttaaaatc aaaaataatt tattgttttg cgactttagt aatggtgtta tctacgctta
    16741 taatgccttt ttcagcaata agagctgaag cagatgtcac aaaaccgaca agtgcaaaat
    16801 ttacagaaac tggcgtaaaa acagacggtt atattagggt taatatgccg aatcatccaa
    16861 atgaatggat gatttcaagt caatttaaag attctcatgg aaatattgga tattgtatgg
    16921 attcagaatt gccatcccca acaggaagtg gagccggaag cttgaagtac aagggagctg
    16981 gcagtgatga gttctatcgt atgtttaaag gtggttttcc atcaaaaaca gcaaaggaac
    17041 tgggtgcagg aaatgataca gaagcatggt atgcaacaca attagtttca tgggttttag
    17101 ccggaaactt taaagtttca cagattgtat ggtcacatcc aaaccatacc gccgcagaaa
    17161 cagctcgtgt aaaaaaagca tttgaaaaaa tttatgacta tgctaagaat ggaaaagata
    17221 cgcccaacac tgagttttct atcacagctt ctaagacagc tgacgaagga aaatatcaca
    17281 ctttcacata taaaacagca tcaaataaga ctggtaatgc gaagctcact tttacatcag
    17341 caaaaccagc tggtatgaag atttatgatg cagatggtaa agaaattact aacaacactg
    17401 tgaaattaaa ttcaagtttt actattaaag tacctgtgac tacaccaagt ggtactttgt
    17461 catttaaagg tactgctaat gttagcacaa ccaatccttt tacttttgat ggacgaggtg
    17521 tgtatcaaga tgccgtagtt atgatcacta cttcagaaac aaaggactct aaatctttga
    17581 gtgctaaatg gacaagagct gttggtcagg taacagttaa gaaagttgat caagatggaa
    17641 atgctttaaa aggagcggag tttactctaa ctgacaataa caatgctaaa tctgttaaga
    17701 caaccggaga tgatgggtta gctacgtttg atttgcaaca aggcttaaca tacagcttag
    17761 aagaaacaaa agttcctgaa ggttatcaag gttcatttaa aaaggatggt attactgtta
    17821 ataccgatgg acaagaattt agttacactg ctacgaacac aattaaaaaa ggtaaagtaa
    17881 aagttaaaaa ggttgaccaa gatggaaaac cattagctaa tgctgaattt accttgacgg
    17941 atgattcatc ccaaacacaa gcagaaaaaa cagatgaaaa cggacttgca agcttcgata
    18001 ttgtagcaaa caagacctac agccttgaag agaccggagt accaactggt tatacaggcg
    18061 tattcaagca agaaggaatt accgttaaag atgatggaca aacttttgaa tatacagcta
    18121 caaacacttt gaaaaaaggt ttagtaaaag ttcataaagt cgatcaagat ggaaaacctt
    18181 tggcaaatgc agagttcact ttaaccgatg aaaaaggtgc aacacaagta gaaaaaacag
    18241 atgaaaatgg acttgcaagc ttcaatattg tagcaaacaa gacgtatagc ctagaagaaa
    18301 ctggagtacc agtaggttac acaggtgcat ttaagcaaga gggtatcacc gttaaagacg
    18361 atgggcaaac ttttgaatat acagctacaa ataatttgaa aaaaggtgta gtaaaagttc
    18421 ataaagtcga tcaagatgga aaacctttag cagatgcaga attcacctta acggatgaaa
    18481 aaggtgtaaa agaagttaaa aagacggatg caactggtct ggctacgttc aacattattg
    18541 cgaacaaaac ttacaactta gaagaaacaa aagtaccaac aggttacaca ggcgcattca
    18601 aacaagaagg aattaccgtc aaagatgatg gacaagtctt tgaatatact gctaaaaaca
    18661 ctttgaaaaa aggtgtgatc aaagttcata aagtggatga tcaagggaaa gcattagcaa
    18721 acgcagaatt cactttgaca gacgacaaag gtgtaaaagt tgtacaaaaa acggacagca
    18781 atggcttggc aacatttaat attgttgcca acaaaacgta caaaatcgaa gaaacacaaa
    18841 accctaatgg ttatacaggg aaatggtcta aagaaggcat caccgttgct gacgatgaac
    18901 aaacctttga atatacagta attaatcacc ttgtacctga aacagtaaga acaggcggaa
    18961 tcggtacatc agccttcctt cttgtatttc taattgcagg attgagtatg gtgctactgt
    19021 attatcgaga acagcacaaa gcaaaataaa aaagtgttaa tggaaaagaa gtaaatatga
    19081 aaaaagaagg ctgacgtatg aaatcaaaaa aaattttttc aaatttaatg ctatttggta
    19141 ctttgctagg agtgggattg ggcgcaagct caatctcttc tagccttgga ctaggggggc
    19201 aagtagcata tgcacaacaa aactataatt atcaaggaac tggaacgatt catatccata
    19261 aagtaacaaa tactaatggg gatgggaacc ctgtctcaga tattgataac aaagggaaag
    19321 aaatagcttt accaaatggt gtaaaacctc ttgaaggcgt tgagttctct tatgtgaaac
    19381 ttactaaaga tgaagctaaa tccttgggat ggacggatag tgatactaca aaaggtcaac
    19441 atattgatga tgctaaagca cgattattac taaacaaaaa atacagtgaa gtaagtagaa
    19501 tgaagactga ttcacaaggg aatatagaca tacctataca agtaaataca gacgatttaa
    19561 cagataactt gtatttgatt gttgaaacag gaacagtcaa aggtgtagtt gaagaagcgt
    19621 atcctatgat tgttaacgta cctgaactaa acggatcaga tgatcaatac tttaattatg
    19681 atgtacatgt ctatcctaaa aactatttcc aattaaactc agcagagctt gataaaaaag
    19741 acgaagatgg aaaggctctt gccggaactg tttttgaatt gcgaaaagat gatggatctg
    19801 atcaggttgt tggaacttat aaaacagaca gcacaggtaa attaactgta gatggtttgg
    19861 aattaggtga ctattatttc ctagaaaccg acttgggaac agatgctaat aaaacaacct
    19921 atttactaga tggtaaaaaa ttcaaattta gcgttaaacg tggggagact gctaaagtag
    19981 ttcttgatgt taccaactac aaacgacctg taattactaa ggtaattgat aaagaaaccg
    20041 ttgatactgg cgaagatgtt caatatacat tgaaaccatc aattcctggt aatattggta
    20101 attacgaaaa atatgttgtc aaagatgttc taggtgcaga gttaacttat gattcatcag
    20161 aagtgatcga aggaatgact ttagatactg attacagtat cgaacgtgac ggacaaacga
    20221 caaactatgt ctttactgaa tcaggtatgg ataagcttca gaaacaattt gatgcagggg
    20281 atcgcttctt tacaattttg atgaacgctc atactaatag taaagctaaa atggatacac
    20341 cacttaagaa tgatgtttca acgatctaca acaatggata tgaacccgaa gacgaaacac
    20401 cagttgatca cgcttataca atcattggtg atcaccaatt cattaaaaca gatggagata
    20461 caagcaaagc attgagtgga gcaaaatttg tagtgaagaa caaaattgat ccgaataaag
    20521 ttacttacct aaaacaagat ccaacaacga aagctgttac ttggattgca gataaatcta
    20581 aagctactga attcgtttcc ggatcagacg gtaagttcca aattgaaggc ttgcaatata
    20641 cctatgatgt agattttgat aaacaaggta atccaacaat cacagataaa aaaatcaatg
    20701 attatgctct tgaagaagtt gttgctcctt caggatatac accaactaga aatgatgttc
    20761 catttgtggt atcgaatgat gatgcttcta gcgaagtaac agacatcaag aaccttaaaa
    20821 cacctgaaac agttcgtaca ggtggaattg gaacagtagt atttctagtg gttgcaggtg
    20881 tggcaggaac agggctatat gttgtctaca aacgagaaca acacaaagct taatgaaata
    20941 aaattcccta gagtgttttt ggctctaggg tttcttttta aaaagtgtgt gaaaagtagg
    21001 tatgagcatg aaaaagaaga atatcaagtt gatcatctta aaaattggga tgttgctatg
    21061 tttaggagta ggtctatatc ctgtaattac tcaggcttat acctactacc aaactcaaca
    21121 aacactaaac tcctataagg aaaaatatga tgaagcttct gaaaaggaga atgaagaagt
    21181 cttcaagaga tattcagaag ttaataggaa acgaaaagac acagaacaaa cctcagtcac
    21241 gattcctgaa gataataaca atattccgtc aaatgtaaat cttcagaagg ataaattagg
    21301 tgaattagtg ggtgaaattc ttataccaaa gattaatgtg gatttgccaa tttatgatgg
    21361 tgtaaacgat tttcaactat cagcaggagc aggaatatta accggaactg attatccaac
    21421 tggtgggatt ggaaaccatt ctgttatatc agctcattcg ggcattccta ataaaaaata
    21481 ttttacagat ttagagttgc tcaaacttgg tgataaattt tttattgata tttcagggaa
    21541 aaagcttgct tatcaagtag atcggataaa aacaatccta ccaaccgaat ttgaggattt
    21601 gcttcctgtg gcaggaaaag attatgtaac acttatgaca tgtacacctg ttggagataa
    21661 ttctcatagg ttactcgtta gaggggttag cataccttac caaaaaagta ttgttgagaa
    21721 agaaaagaag aaagaagatt taaaggtaaa ggcgcagatg aactggtatc ctatcgtagt
    21781 tgtaggggtt ttattaataa tagctgtgat agtcattatt aaaaaaatag tagcaaagag
    21841 acgaggaatg aaaaatgaag aataaaatac tacttttttt gactcttatt tgcactttgg
    21901 ttttaacaat ttatcctgca aatcagctct atcatcaatt caaaacaaaa gagaatgtgg
    21961 cggaaatcca agagaaaatt gagaaaaaac aaactccttc aaaagaggaa gtggcaaaaa
    22021 aagtcgaaca aataaaatcg aacagcggta accaaggatt agacaatact cagaaaacag
    22081 acggcggatc atttgatatt ggtgaagctg aaggaaaggt caatccttac acaggagatg
    22141 ttttttcaaa aaatcaaacg aaagattttg aaccatctac ctattcaggg gcggttggtt
    22201 atgtctatat tccaaaaata aatgtgctag agcttttgtt tctaggcgct tcacaggaac
    22261 atttatatag aggtgtggca cagatgagtg ctactagtct acctttatca ggtaaaggtc
    22321 atcaaacagt aatagcaggt catcgtggcg gttatacgtc accacaattt ctttatgttg
    22381 atcaattagt agccggagac cacatttata tagattatct tggtgaaaaa gcagtttata
    22441 cggttttccg aacagacgtt attagaaatt acggtcagaa ttcaacactg actgatattc
    22501 ctgatttaga tatgttaaca ctttatactt gtcatccata tcctcagaac tacgatcgtt
    22561 tattagttag aagtctaaga gatgaaaaag caaaatacat cacgccacaa gtaacagttg
    22621 gcaataccgc atacgctgat gccattgata gcgagtccgt ttcagataag acagaaactg
    22681 ttacatcttc taatgattta tttgaggatg ttgatcgtgc caacaaggaa ttagatggaa
    22741 ataatgatct taatattccg gaacaaggta gcgtagagat gcaagacaga acatttgctg
    22801 aaaaggcaag ttcaatattc acaggaatta ccaataaaca tcagaaaatg cttttagtca
    22861 tttggactgt aataggagca ttagcaagtc taaaggttct tattctttta atcaaagagt
    22921 ttcgaaaagc ataatgaaga ttataaaaat tgatagagta cagtaaaaag ggattgatac
    22981 tattattgat ctctttttta ttttgaatag agctagattc acttttaaat aaaatcaaaa
    23041 ctgattttaa ttctaaagaa aaagtcaaga aaaaaataca acaaattttt ttatcagaat
    23101 atttatcaga atattattag aaaagataaa ctcaaaagct taatttaata gggttattgg
    23161 ttgtatttag aaataatgta tggaaaagct ataaagaaat agataagatg tagaaaatct
    23221 tatttgtgaa tgaaaaacaa gtcatcgtaa aatattaata ggaggtgtag taatggtggg
    23281 aatatcaaaa acagctttag actcattagc taaactattt agtagcaggt ttgatagtgc
    23341 agaatttgtt gaatatctaa gccaaaacga aagtggaaaa actctgatcg aaacaatgaa
    23401 aaaagactat ttgaatgaaa atgactttcc gacatggacg aatattgaag atgctacatg
    23461 ggatgtagtg tgtacgatat attctccttg ggtaacgatt gctgattttg ttttagataa
    23521 aattggaggg gatacatacc ctgatgccaa atctcttgct acaagtgact ttaaaacgtt
    23581 ctatggttat ctaataggtc taataggcaa tggaatagat ttgaaagtta cgccaaaaca
    23641 aacacctgaa gaaattgaaa aagaaaaagg agaggttcaa atggcttatg caaatgacag
    23701 agaaaaagta aaattattgg aaggtaaatt atctgaagaa gaacttggaa aaatggtgca
    23761 agaaatcaat gaagacagca actattttcc tgaattgaag gtatatcaaa atgacgaaga
    23821 tttctttaat gaaatgttta gtaatagtcc atgggaagca gtgagtaaaa caaatttagg
    23881 agaatggaac tttcaagatg atctagttgc atttagcaat gatgggtatt tacgatcata
    23941 ttcagaaagt gagtatagag ctgaattaaa aacgtatgaa acggatattc tgatgagcta
    24001 tttaaatcta ttagagagtg gtcagggaga gttaagagat aaagttgaag aactattaaa
    24061 agaagagcta tagggattat ttcaacataa acacaagcag aaaactacca aacaaaacgt
    24121 accatgcaaa aagtcggtta aaccggcttt ttgctctatt atgagaggag atcaaaccat
    24181 gagtgcaaca accgatatgg ctttagaagc agtaataaaa gataatacag gaaatgtcga
    24241 aaatgtagaa gactttagcg atattgcaat caatctttca gcatggattt cagctgtagg
    24301 agaagaaaat atcgaatttg agatcaagaa tatggatgac ttaaaagcaa aatttccttt
    24361 tatcgcttcg aaactaagtc aatttgccga ggataaatcg tggaatgaat tagttagttt
    24421 ttccgaaaaa atttatgata ttacgcaaga agatgagtgt gtttcatggg aaatgaataa
    24481 tcaatacaag aaaattgatg ctttcgtcaa atcacgtata gaaggaacag cttttgagtt
    24541 tgaaggtata gataccgcag ataattggtt aaataaagaa tcctttatta aaagtatagc
    24601 ggatgatctt gaaaaacaat ggtctaagga agactatgca gagtacctaa aaacagaaag
    24661 agatacagag gtgaaagaaa aactcactga ggtatgtttg gatgaacata ttgatcccaa
    24721 tatcgtaaaa caagaagact atgaagtggt tattgataaa gttcctactg attttgagga
    24781 agttgtaaag tatatagttg aagaagcatt atcgcaatac tcttcagatg aggaagtgga
    24841 cgaagaaact gttcgtacca gagtttggca actggttttt gatgacaaag attataaata
    24901 tttgagtgat caaaactcgg ttaattggag tgtacgatta ttaattgatc aaaatgatat
    24961 tgaataaaat agagctgaaa agctctattt tttttgataa aaaaactagc tattttttta
    25021 aaaataattt ggttcaaaat ttattttttt aacttgataa ttttttgcca tcctttttta
    25081 aattggctat atatcaaggt ttatagtggg gataaataaa aatacatttg acaaaattta
    25141 caatatagtt tattatatat ttatcttatt atgataacac aataaaagga atgatggtat
    25201 gaaaaagaag aagtttagtc gatcgttgtt aggaatttta gttttagttg cggttggtct
    25261 tagtggcaag ggttactttc agaataacag cactcaggaa catgattttc agatcaaaag
    25321 tagtgttcag gtaggtaata aagcagacag tgaatcaaaa gaatttttag ggatacgtta
    25381 tgatccaaac aaatatccaa ataatatcgt aaacattaat gatgggaaat atacactgac
    25441 aaaagaagac catgaagcat tatcagaaaa aggcagtcaa accttttggg taaattatgc
    25501 agatttagat caacttggaa gagcaggaga tgttgaagcg ttgatcacct atgatgctat
    25561 aaattctcac tcatctaaaa atgtggaacg tccatctttc aaaagttctg tccatattgc
    25621 aggagaatac aaggatggag tatttgatca agagagagat acttgggtcg gcaaagattc
    25681 aaacaatgaa atcactcagc tagaaggata taaaggttat ctctataaca aaagtcattc
    25741 attagcatgg tcgctaggag gagatatgga ggtacacaat ttaacacttg gaacgagagc
    25801 gcaaaatgtt gggaaaaatg atcagaatgg agggatggct tactcagaaa cgattgtacg
    25861 tgatgcaatc tataaaaata agaatgaaaa agtattgtat aaagttgatc caatttataa
    25921 agggaatgaa ttggttcctc gtggttctca tgtcgaagct ttctcagtta acgataatgg
    25981 aaaaacggta aaccttaatg tttatgtatt taacaatcaa aaaggaatca acatcaacta
    26041 tcaaaatggt acttgggtaa gagattagaa attgagaagg tgaagaattg gaaacaataa
    26101 gcatcaatgg attagataaa tcagttgcaa atcgaataaa aaaaggaaat ggctactatc
    26161 ttctgaagaa gggtaaatat tcagttgcta gagagttaga aacaatgagt atcgtgtatg
    26221 tagctaagaa tcattttgac gtagaacagg ctatttttga tccagattct gaaataggga
    26281 aatgtgttga attatcagag aaaactgtta gtacaaaagg ggcgatgatc attgagagag
    26341 aaatgttaga cgaaatcaga gtaatcattc ctaaagatac gcagatgtgt gaggacagca
    26401 taagtgacga tgaaccaaaa tcagaaagaa aataaggaga tattcagatg agcgaaaaat
    26461 ccattgaatt aaaggaatat aagcgaagcg atggagaaaa atattatcct gtagccagtt
    26521 tttctaaatc agtatatctg gttggacgtg cattggtagt tggtgcaatt ggcatatata
    26581 ttttgcattg ggtaacaaag gttgtacaac tgcttgtaga taccttagta agtattcttg
    26641 tctcgttaaa tgatgttaac ggaacagatg atttaggatt aaaagaaatg tttaaagagt
    26701 tactcaatgc gttttttccc aattatttaa gttattcata taatgtacaa agcttttttg
    26761 caaagctaca cttggtagac atctctattt tagtattaga agcaggaacg gtattctttg
    26821 ttggatattt ggttactttg atgttcaggc atcactatgg agaacaaaga ccattttttg
    26881 atgatatgga aagtagaagg ttgaaaagag aagctctaga agctatggat gtgaagtatg
    26941 atccaaacaa gattatagga gatgaaacga acaacaaaaa aagaaaacga aacaaaacgc
    27001 aattagaatc cgatgtgcta tcaacgctta aaaatatcaa aatttctgtt catacaagac
    27061 gtgatctaag tgtcaatgaa gatattcgag aatatatcgt aaaaatcccg caaccaaaag
    27121 ggaagaaagt tagagaaaca gttttacgac aaattcaaga tttagggtcg atcctgacaa
    27181 gagcaacaag cggacgagcc aaatttggtg aaaaagaaga tgaagtttca ggcgattatt
    27241 tcattttccg agcatcagta aatattgaaa gagaacgtaa ggaaagagta agtaccaaaa
    27301 acaaagaaac ggaaagagca acatcttcaa tcgcagtttc aaattcacaa ttttcttttc
    27361 caatcaatct ctttgccgat aattccaaaa atatccaaaa ccaaaccgaa aaagctagaa
    27421 aatatgccga aactcaaaag caatctttag aactttatct atcttctgct gacgtacctg
    27481 caagtctaac agatatgcac gttgggaata catctattga atatttgttt actttatctc
    27541 gtaccagaaa aattcaacta agctcaatga aagaagaaat tgaaacttac ttgcatatat
    27601 caggtgtaat cgtgcggatc aacgcagggc gtattcaaat tactctacca ttaggagaaa
    27661 atgatcgtat tccaattgat gtaccatcaa tgatcaatag cgtgttttaa aagacatcac
    27721 aaatagaaac agaaaataca aactaccagt tcacaaacag aaaagtaccg agaaaagtga
    27781 ggaatagaaa tggctatgaa attattagag aaagtcaaaa agagagccga aaaagctgaa
    27841 tctattttgc tagataaaga acctaatata aagcttaatg gaaaattcag tgtcaatatg
    27901 ttgaacacaa aggctaaaga cccgacagat gctatttttg gaattaagcc tgatggcaca
    27961 attgctcatt tttgcatcag cgaaatgcca cacatgttgg ttgcaggaac gacaggatca
    28021 gggaaatcag tattactgaa tgaaattctt gttacagcaa tgtgtcactc aacgcctgat
    28081 gaattaaaaa taggaattgt agacccaaaa agggttgaat ttggaagata caaaaaattg
    28141 ccgttcatgt tggctgatcc aattacagat atggatgaag cttatgattt ttttgaatat
    28201 cttgtgatct tgatgcatga acgttacaaa ctgatggaaa aagcagggtt acaaaacatc
    28261 acgctatata acgaatatgc cgaaaaaaat ggattagata gatttcccta tgtgatctta
    28321 ttagttgatg aatattcaca gttggttgga acacataaag aagtagaagg tttgattgtt
    28381 caattaggac aaatggcaag ggcagcaggt attcatgtta tcttagcaac acaatctcct
    28441 cgatcaacag ttgtcactgg tattatcaaa gccaattttc cgtcacgtgt ttgccttatg
    28501 gtagcaagtg atttagaaag taggattgta ttagatgaag gcggtggaga aagtctaagt
    28561 ccaaagggag atatgcttat taagcttgtt gatggaagta tggttagagc gcagggagct
    28621 tacatcagta acaaagaaat tgaaacaatc ttcaatcacc ttagaaatac tatgccagaa
    28681 ccagaatatg ttgattaccg agcaatcgta gctgaaactc gtggtgaggg cggtgaagac
    28741 gaggattttg gtggaattgg taaagctcct gtaagaaaat ctgctaaaag aaatttgaac
    28801 acacctttag caaatccatc atctaaagag ccatcaattg aaaagaagag tgcgtttgct
    28861 attaagcttg aaaaaaataa agaagaaaaa gctaatcagg gagctaagtc actagaaaaa
    28921 cttcagcaag aaaaattaga aaaactagaa aaagcattat catcatcaac ttctgaaact
    28981 caatcttcaa agggtataga taatggacaa tcaattacaa ctaaaaacaa gcctaaaaat
    29041 agtaattcaa atctctcggt aaatgttgtt atcacaactg ataaatctga aaaaaaacaa
    29101 gtgaacggaa ctacttcacc catcatgcaa aaaatgataa aggcaaaaaa acaggtgcag
    29161 aaatgattat cattagttcc tttttgagat ggctaacacc atataaatat acagatgaaa
    29221 tagttgagaa gcgagcgaag aaaaaagtta aaaaaacgat gttaactcct aaagaaatgc
    29281 tagatcgtgg aatattggga gtgaaggttt tagaagtaaa ccaaccgttt gaattggata
    29341 atgcgagaga taggttgctt agagctgaag ttgatgtcgc atacttttat catgataaaa
    29401 gcaagcatca aatagctatc aaattcaatc caaaatcggc atggcgatac caagcaagag
    29461 atgacctaaa gcgtaggaag ctgaaaccga tgctctatcc tgaaggaaaa gaggcatttg
    29521 atagaaccca tattgttccc attggatttc atggtacaga gtcagataac cgcctattgg
    29581 tagggtggaa cagctcacaa aatagagttc agatcaataa atttgagaag aaggtaagaa
    29641 aatttaacga tcggaaaata atactttggt ttgccaatat tcagaagcaa ccagatggga
    29701 cagcaaagtg ggaagcggtc atatttgatg aagatggcaa aaaagtaatg tctgaagtat
    29761 ggcatgataa agctaaattt gtttggcagt agaggtgaaa attgtgttaa ctaacctaaa
    29821 actatataga gagggattta acgaaaaagt aagtatcggt gaatctattg aatatttagg
    29881 aaagaagtac attattattc gtattcttga aattaaaaaa ctttatttta gtaaatataa
    29941 taatttagca gttagagttc tcgtccaaaa ggttggaaat ccaagtgact atagaagtga
    30001 ttaccataac tataaaacag aatcatctgt aattaagcgt tataatcaat caaaaaatga
    30061 tgagagaata ttcaaagtag gagaaattat tatttctaag tatgggatag catacgaaat
    30121 agtttctatt aaaaaatttt attatgaatt tgttgatttg gttgtagaat attctgttcg
    30181 attgatcgtt ccgtggagta aagaagaaat taatgaggca ttaaaacatg aacgaaaaag
    30241 tacattcaaa gttttagaag gtgaaaaaaa gtgaaaacag accttactag gcaagctgag
    30301 aagtgcttat ggcatgaaac aaatcgcatg ggtgtatttg gttgtttcga agtcactatc
    30361 ggttgggatg gcagtgaaag agtagattat ataacttatt cagtagataa cacagttcga
    30421 tgttatgaga tcaaagttac tttagctgat ttaaaaagca aggcgaaaca gacttttatc
    30481 ggtgattata actatttagt tgttactagt gatttgtggg agaaaatgca acaagacgat
    30541 aaacttatgc ggaaatatta ctatcaaggc gtatacgtgt tcaatgaaaa atatcctagc
    30601 ataataagtg ttaagaaagc aaggaaacaa aaagtatcgc taggtacaag atcaactgta
    30661 ttagaaagca tggttcgttc tatgaatcgt gaagttaaga aactctataa agtaaaacca
    30721 ttttgggaga tagcagaggt ggaaaaagga tgattcaaac atttgcaaaa atgagtagaa
    30781 gtgcttggat tgaaaagctg gaaaatgatt tgagtgttat gcgattagct ccaaagaaat
    30841 tcaaacgaga gattgcagaa aaagaagcaa ttttgtcggt attgaatgcg gtagaactgg
    30901 acgaaccgaa aaagtcagtt gatgtacctg aaaatgtagc agagttacta gattattatc
    30961 gtaattcgtc agatgtcgat ttgttagctc tgatattaac atttcacgat tggtattact
    31021 gtcaaaatga agatactcag catgataaac atgataaagc agttgactgg ttaatagaga
    31081 atccagaaaa gttcatgcgt gcttggctag atggctatga tagcaagaaa aagccactgg
    31141 aaagtaatga ggaaacgtat ttaacggcag aacaatatga ctatgctaga aaaacaggag
    31201 attgggaatc tggtaagact ttcaatcaca gaaaagatca accaaaaatt agtttttcag
    31261 atatagccgc aattatcgaa ggtatctact atggacaagc cgatgaagag atcttttcta
    31321 tacaagattt attagaattt ttgaacaaaa ataaggatag ctttgtagaa ctaactgatt
    31381 atgaggagga tacagcaaat ggaaaattat gatccaaata tgcgatgggg tacacatacg
    31441 cttaaagttt cttttcaacg ttgggattac aagggatttg tgacttttag aaaagctgga
    31501 aattgtaaag gattagatgt cttagcgttg gatgaagact atctatatga ccatccattg
    31561 acggataatc caatcggatt tggattgctt cctgaagatg atgagggcaa tgaatggttc
    31621 aaaatgattc ttacaaacga taaaggtgat caattatttg tagaagatac ttggtcatat
    31681 ttgagtgaat atattgttag cattaaaatc attgattttg tagcagataa agaaaaagag
    31741 attggagaag gtaaatctaa ttactagcta atgaatagca actttggagg ataagtcaaa
    31801 agaataaaaa aagaatactg tgtgtcattg cagggatgta tctttgcatg atagtatctg
    31861 cggttaccat ttattggtta ggaaatcagc aaaacagttt aattgttgat ctgggggagt
    31921 taaaggttgg attacgaatg actagatggc ttttattagc tcaaacagtt ggtttagcca
    31981 tattgacttg gatatgtgtg gaaaaaataa catctaataa taatcaagag attgttgaat
    32041 caacaaacct aagaataact gaacaagcaa ttgaaaagca aaaagacaaa gaaaaaaagg
    32101 aaataatgtc aatttattta tctagtggag catcattttt tcatgaaata gattcgatga
    32161 aactgagtag tcaagaaatc attgatagat ggaaaaacat gcctctaggt ggtgagttaa
    32221 tcgttgaaga tagtgatggt tggtcagctt ataagaagga cgagattgta gctatcacga
    32281 ttttgtttga atagtaatat attaccacta gataatctga atatgttgat ctgctagtga
    32341 cgtaccaaat gcgtttaata gaaccttggt cacaggcaga aattgataaa gcagtaaaat
    32401 tgaaccgatt atcaaaattt aacgtattag gaaatgcctt ttaaaaatcg caatacacaa
    32461 acagaaaaat accaaaaaat tagcaatgaa cgtaggtaag aacatgacaa taaataataa
    32521 taaccctaac aaatataatg ctcttgtcca atgctatatc gaaaacaaaa ttacaatgca
    32581 agaagtcgct gatgaattag gcaaatcaaa aagcctagta tcacacgact ttaagcacaa
    32641 tgtttttccg aacccgattg agctgaggaa aaaatttcaa aagagagttt atcaagaaat
    32701 agggaagtgg attgatgaag ggaatgcaat tgacccttta attgaaaaat atcctttttt
    32761 aaaaagcaaa aataaaattc aaaggttaat tcgtcaaggc gatattcaag ctaaagaacc
    32821 tgttttgaca accaatgatt tggctaaaat aaatcttcat aaacagatta ttgaagactt
    32881 tgaaaaaaat ctttcaacaa ctgaaatttt aaaaaaatac aatattccga gaggaaagct
    32941 aacatcgact ctttttagag aatatggaga atcggcagtt actaaagcaa aggaagtagc
    33001 gaatgagaga aaaaaacaaa aatagtagtc gatacttagt agcgactgta gtttttgttt
    33061 gtgtattgat tttcctgttt gattttttac agattggaaa aagtataatt ggaaatacat
    33121 tgagtgcaaa ggaaatggtt gctttaggtg gtttgtatga aggacatttg ttcccgaata
    33181 tattcatttc tatcgtttct catattaact tgtaccattt aatttctaat ttattgttct
    33241 tagtagttct tgaagaagca ctgaatgatc agtatgagtg gttaacatta ttgatcgttt
    33301 taatcatatc aggatttcta ggaagcttag ttccttttct gctacaaagc aacatcgtaa
    33361 gtatggggct tagtggaggt atttttggat ggattgcttt atttgcgatt gcatacatcc
    33421 attttgatag caaggaacat ttattactaa gtgtttttgt attattgata atcggcattt
    33481 tattggtatc tacttttgaa tcaggcgagg caaatgtctt gtcacatgta atcggatttg
    33541 tctgtggaat gatcttggga tttattctaa agaacgtttc attgatcaaa caaaagaatt
    33601 aaaagggagt gctaaaaatg ccaaaaagaa aagaaaagaa aattccagtg tttttgtctg
    33661 tctcagaaat gttatcactt caaatactgt taagaaaaaa gattgaaaca atagacgaag
    33721 aagttagaaa taaaagggct atgtacgaac aacgtgaagc gctaagagaa cgaatccact
    33781 attttgatga tatacacact aaaatctatg aagcacgtac aaatcacgaa gacgaaagta
    33841 aattaggatt agctcaacaa cggatacttg aatggcttaa tacgaatact gatcaagaac
    33901 cgttaagagt gattagtaat ctttttgaat ttggaacgaa gcattggttt aatgctgtag
    33961 agaaggatgc tgacttacaa gaagcgtttg atacgctaag taaggatagc aaatccatgc
    34021 gagatttatt gattacttat ctaaatgagc atgagtttga acaaacgaaa accaaaaaga
    34081 aaaataaaga atagaaagtt gtgatgaatc atgctattaa ccctgttagg ttatttatgt
    34141 ttaattcttg ctttttttgg ggcaatcgct ataattattg gtcaatttca aacaaataat
    34201 ccgattatgc gtaacatagg cattggaatt gtgattgtaa cctttattgt gtttaatgcc
    34261 actaagattt ttggaagtaa cgataaacaa tttggtatat cgggagttaa taatagttat
    34321 gctccagatt ctttgggaag ggtagtaata gatggaacat ttgaaaatgt aacgagttat
    34381 aaaaatgttt cgctgacagt gaaggaagat ggcaagaaag catcagacga cgttctcgct
    34441 actattaagc cgtctcaatc acaatttgaa gtgttttata cagttaaaga gaatagccct
    34501 gtacacaagc tgacattggt ttttaacgtt gatggagaag aatactataa agatgtaaaa
    34561 ataaataaaa catcaacgaa aaagattatc gaatcagcga aaaaagaagt agctacagaa
    34621 gaaagtacaa ctgaatcaag ttctactgtc gaagcggaac taccagataa aattgatttt
    34681 gatcctgaaa aagtcaaatc gtttgaatct gtttctggtt ctatggctga tcggtttaac
    34741 actgaagtct tcaaagctat caaaactgtt aaattggata ctgaaaagca aatgattaat
    34801 gttaccttat tcaattcagt tgaatctatg gatcaggata aaaaagttac ggttgcaaga
    34861 gaactaggaa aaagagtaat tggtttgtat cgtggtactg ctaaaccaga ttcagacggt
    34921 gcagatttgc cagttcatgt agtttatgaa gacggtaaag tttttggaga ttctacagca
    34981 aacgaagcat taacgattaa attggctaaa tagccagaaa gttataataa acaaatggtg
    35041 tcacaccaat aatatatagg tgtgacacct tggagatgat agctgatggt agtaaataaa
    35101 gaaaaagtta gaaagtatgt gactttaaaa atagcttctg ttaaatattt agaaaagcga
    35161 gctaaagaag aagaaagagc aagaggtaag aaagtaacag tttcagagtt gttagaagaa
    35221 ttgatcgaga atgatcaaac aataagacgt gcatttacta ataggtctat cagataacaa
    35281 tataattaat aaaaaagaaa gagtgatttg gtcttagact aaatcactct ttttatataa
    35341 agtttcttta cactcattcc gaataatgtt aaaattcttt atatgatata tagttccttg
    35401 tcagaggaag agataaccag caatattgga gggataataa gtggaaaaca ataatgatat
    35461 tagacatttt agcattgggg aaagagttac aacagtaagt gaattatcaa aggattatag
    35521 agataaagag ggaacgatta tttctcttaa taagaatcga agaggcgttt ggcaatatgt
    35581 tgttgattta ggtgatggcg ttacagttga gtgtaaagat agtcaactga tcagaaataa
    35641 tggcagtcat tccattgaaa aagcaattct tgtataccca aaagtatcaa gtaagatcat
    35701 gaatgactgg ttgcttggaa aatttggtga gtacaataaa aaagaaatcg cagaagtgat
    35761 cggcaaatct tatccaacag tattagggta tctaaaaaag ataacgagta aagaagcaaa
    35821 aattgaggat gttttaacag taagagagct tcaatcatta atcgagtatc ggaataaaca
    35881 aataacaaat cctgagtacc ttagaaaaga agatggtcta ttgaaacaat tggaacaagt
    35941 aaataaaatc cggaagatgc aaaaggtagc tcctttaagc cttgatacct ttaaaaaaat
    36001 ctatttgaaa gagatcaaaa aagactaatg tggactgtaa ctttaccgtt ccaacctgta
    36061 tctgcaccaa gaccaagtgc aagaaggaat gctgctgatg aaactaatga cgtagcagag
    36121 aaaaggattt caacctacta tgataaaaag tatcttgatt atttgaaaaa aataaagagc
    36181 tttatcgaag atcaagattt attagatgat gaattttact cgattgtaaa tgatcctatg
    36241 ggcgcaatta tggaagtgga cttttactac cagataccaa aaagctataa aaaagtctat
    36301 aacattatga agacaacagc gccagattta gataatttag taaaaagtgc tatggatggt
    36361 atttttaaca tctcagctat acgagatagc catatcacag gcttaattgc ttttaaatat
    36421 aatgtggcga acgaaggaaa aacagttgtg aggatcaaac gatattcaga atttgagtgg
    36481 gatacttctg aaggattgaa cggagatata tgggaagcta catttgattt taaaccagta
    36541 gcaacgccaa gaccaaagtc taaatttaga ggaaatggga ttatcactta ctatccaaaa
    36601 gagtacaacg actatttgga aaatatcaag aatacgctta aagagaaaga tttggtaaat
    36661 gatcaactga aaaaggtaat gaatgctcct atgggggtta tagctcagat agattatttt
    36721 taccaagtga gaaaagataa gaaaaagctt gattcactga tgcgtacttc acagccggat
    36781 attgataatt tagtcaaagg aacattggac ggaattttta acaaggaaat aggcatcaaa
    36841 gatagcaggg ttgtagggtt aattgctttt aaatacaata cttttgaaaa gtcgaaaaca
    36901 aacgtgagac tacaggagat gggctgatga ataataatga aaaaattctt catgtacttg
    36961 atagctttga aataattcaa gaagaactaa aaaaatatcg ggatgttttg gaacaaagat
    37021 atgattttgt caatcagcaa aagagtaatc acatggattt cattctcaat atgaatgact
    37081 tgaagaagaa attagttgaa cgaaaagaac aagaaaagtt gatcaaagct tactttgaac
    37141 tcggtgaaaa agaagttaaa aatgcaatgg aactgaatga agagcgcagg gttttagatc
    37201 agctgttaga acaattattg gtgatgtttc aaaaaggacg aatagatgag gatttaattg
    37261 aagaaggatt gagaaaatat ccttcaaact caggtatcgg aatagtgctg aaagcgattg
    37321 atgaagaaga aattgaagct ttcataccgc cagaggattt tgaatcggca atggaatata
    37381 taaaatatta tagccaaggg atcactgctt ttagagagtt tgatcctgaa gatgttattc
    37441 atgacttgaa caacctaaaa gaatggtgtg aaagttatgg agtcgatgat tccggattgg
    37501 actacttgat cagtattatg gaaatcgaag aagagatgcc ggataagcct gatccaacag
    37561 atattttaga attgatccat gaagctagaa atccaattgc ctatatttct agaggatata
    37621 ctgtattgga atactataag ccttatatat cagcgatgaa ccatttaaga cgtgtattaa
    37681 gggaaaaacg tgaataccgc tcagtgttga atgcaacgaa tagattagaa aaagctgttt
    37741 cagagctaga tgcttattat cgtgaacatt acctgcaagc aggtggtatg ccaagaaata
    37801 cgaaagcaaa tatcagtagg tatataaaaa aagctgagta ggcggagtta gcccataaaa
    37861 tggcaaaagg taacctgaaa ggggcatttt gaatgaaaag ggatgttttt gaattgtacg
    37921 tattagaacg tctagaagac ggcatgatgg cacaagagat aattgatgaa attgatgata
    37981 tgatcagcag atttggtcaa ttggagttga atgatggaaa caaaaattcg gtagtgctaa
    38041 aacaattttg gttgaacaat ttttcgtata aggattttat caaagaaaag gcaaatacat
    38101 tgtactgact aaattcacga ggagcagtga tgagagctta ttgctaagag cagttaggct
    38161 cttttttgtt tgtgtaaaat tatttgtttt ataatacaca tttatacaca aaaaatattg
    38221 acagatagta cacaaatgtg gtaggatata tttgtaagca agttagatta acaagttaaa
    38281 ggaagagcag ttatgaaaaa agaagaacta atagatatat ttcaaattgt tgaacgagca
    38341 aataatatgg gaattatgtt ttttgatcgt atttctttaa agatggattt aagcgttgcc
    38401 caccaagaat ttaatctgcg attaaaagcc ttgttgaatt ctgatgatgt taatttcgct
    38461 catgatgttg taggtataca gaaccatata gatagagaaa acaaacgtat gggtgatgaa
    38521 ttcttaccaa gatattcaag tttatgattt ggcgaaagat tcaagagtat gtgtcattat
    38581 tgataggtac tcttgaattg gaaaggagga atgaatttaa gacaacaacg attatgatct
    38641 taaaacaatc gtttatgtaa ttggcaatct tacgaataat tttcatgcaa taatgacaat
    38701 aaaaaatgaa aaggggtaaa atcaaatgaa aaaattttta gtaggaattc tattcacaat
    38761 ggggctagta ttattatcac cttcagtttc agcagaaagc tctatttcca tgtatcgtat
    38821 gtataatccc aatagcggag agcatctata cactagaagc gttggagaaa gagacaatct
    38881 gaaacgttat ggatggcatt acgaaggtgt cgcatggcaa gctccaacaa gtggtactcc
    38941 tgtttatcgt ttgtataatc ggtataacgg tgaacatttt tacacagttg atgccggaga
    39001 aagagataag atttcacaca caggatggac gtacgaaggt gttgcgttct attcctacaa
    39061 cggagcaaat agagttcctg taacacgttt atataacaaa tacgtgaatt ggcatcacta
    39121 cacgttagat caaaatgaaa agaacgtaat tagtaaacaa ggttggaaga ttgaaggtac
    39181 aggctggtat gcaatgccaa acagcgtacc aaatcctaca cctgctccaa gcactgaaaa
    39241 agtgttgaac gttcctgttg tatggcaagg aaatacaatg ttatgcgaag gagcttcttt
    39301 attagaaggt ttacactaca aaggtgtagc cacaaatcaa agcttaacca gttttgtaaa
    39361 ctatatgcca aaagctaatg acaataatcc ttatcatggt tactcaggag agtggcgtca
    39421 taacgttaat ggaacgtatc aaggcatgat ggctgaccca gtagttaaat gggcaaaaaa
    39481 cgttggcggt aatgccgtca atatcactgg ttcaggaacg aatggaatca agaatgaaat
    39541 tcgcaatggt aatccggttg taacttggat tacttataac tatgctacgc cagagttcaa
    39601 acaaatgcct tggggtcgtg cagtatggaa tggacatgta gttctcgtgg atggcttcag
    39661 aaatggtgca taccatgttg ttgaccctgt atttggcgca aaatggatca atgcaagcac
    39721 gtatgagaga gcatttaatg tgactggaat ggcggttgct gtacgttaat tgatagaatt
    39781 atcaactaaa tgaaataaga gcttaattac tgaaatggta aataggctct tattttttta
    39841 gaggaaattt ttgtaatacg aatctataac aaaaaatatt gaatgtagta cacaaaagtg
    39901 gtatattaaa atcgtagaga ttatgcgaag aggtgatttt gatgaaccaa agaagaagaa
    39961 aaaggttaga agaaataagc gagcgacttt ccgagctaaa ggatgagtta gaagtaattc
    40021 aagaagaaga gtacaaagaa aatataccta aaaatctaca gggatcagaa agatatgaaa
    40081 aagcagaaga atccgttgat caacttgaag aagctgttga tggtttatcc gacatattag
    40141 aattgattga agatatagct agctagagat gattaatgaa gatttcagga gtgagaataa
    40201 aatgattgat atttcactga tagagaagtt acttttctca aataagtaca ccgcaaaaga
    40261 gctggctaca agatggcaaa tatccgaatc agctattaaa gcctatcgtc aaaataaggg
    40321 aagcgtagga tggcgtgatt ggaaagggat cagcattgga aaagcagaag acataatgaa
    40381 acgtgaagga cttcgatcct ataccacttc tgaaaaagac aaataactta atgtttgaaa
    40441 agataaaata tctgtcttaa agctatgtca aattcaaatg gtgaatgttt gctaaatata
    40501 atgcaaaaaa aggaagggaa atattaaatg ataagcgaaa atttgtctta tgagaataat
    40561 aaacatctag ttaaagaaaa taagaaagta gaagattata agaacatgta tatagaaatg
    40621 aaaaaatcac cactgtgtat tcaatataaa aatgataatt ggaagcaagt agtcgaattt
    40681 gtaaaacctc atagtatacg aagagtacga agggggaaga aaaaaagtga acttgtaaat
    40741 agcggaagag cggtaattag agttataacc aaagattatc cagttgaata tggagattat
    40801 attttaaggt taagttatca tgcttttgtt gtgttgaaag aagagcattt caacgagttt
    40861 ttcaatttaa aaagtaagta atcatatttt tttgtagacg tgtataaagt taactaaatt
    40921 gcgaggtgat gacatggtag caaaaaagaa tactctaaaa gaagcttctg aaaaatatca
    40981 agatatgaaa agacgaggat taataccgaa agacaaaaaa ggtatatgga gagaatttgt
    41041 taaggaagtc agtagtgatc gaagtggcgg tgactttgtt ggacgatata cagcaaaagg
    41101 ctatagcaaa cgattaagga tcactgttga atatggaacg aatgaatcag ctacagagct
    41161 gaagcaaagg tacttagata cacgaaggga agcttcaaaa aaatataatg atttcaagag
    41221 cagaggtctg attcctaaaa agaaaaaggg aatttggcgt gagtttttca aggaagaaga
    41281 tagcaatcgg aataagggag acttcattgg acgatacaca gcaaaaggct acactaagaa
    41341 tttagggatc aaggttgaat acggaactgg tgaaagttca tgggaattga gaaatcgcta
    41401 tttaaataca ttgttagaga aatataaagc agaattattg gagttgttcg atgttaatga
    41461 ttttatcgag atggctgaaa agtatggtca tgaagaaggt tttatgatca atgacattat
    41521 ggttattgat aattttacgg atttattagc acttgcgaaa aaagcaaggg atttaagaga
    41581 aacgcagatg tatctattca gaaataaaaa cggaagaaac cggagaactg aatcgagtga
    41641 gattgaagat tactacgatg cctttacaca cgatctggga gcctttgtag acgagataag
    41701 tggtgtaatg aacaaatata gggtctagaa taaaaaagcc ggagatgagc agataaatgg
    41761 gaaacaatag catatacaca cctgaaatgc agaataaaat taaaagactt gtcggattag
    41821 ggtggatgac aagaggaaaa ttagattctt ttagtacgat caaatatctt ttgatggaca
    41881 tttaccgtca gaacaagcaa acaggaatac attttttggg ctatgataag ccggaagatg
    41941 cacctttctt tgttccaagt tcagcctata gagccagtac ctccggtagc atgtataact
    42001 tggatttgtt tgaggaagga gcaaagatga tcgaatatga tttcaacgaa gcctattcga
    42061 ggatcatgag aaattatcct ttgccgtcaa acacttattt gaaagcaaaa tataatacag
    42121 atcaagctat tttgagagcg ataaatagac caaaagtaag accgtatgaa aatttaagaa
    42181 cgtatatgtt ctttttggtt aattttgaag gaacagccaa agaaggaaca tatgctaatc
    42241 caaaatcaca gtcgatgttt gcggattatg gcgaaaatcc caaaacagct aatgagccta
    42301 tttggttatc ggagattgag ctaacactta tccttgatta ttatgatatt aaagagatgg
    42361 aagtcctaga tagccacaca tttttgacga aaaaaggatt actcaaagaa tattttgaaa
    42421 gaatcgagcc attaaaaact gatcctgata cgttgaagct ttataaaaat cttagaacga
    42481 aagtatttgg tgctatcgga caaaaatcat taagagaagg agaaacaagc accttcgata
    42541 aatacagtat gtataatcga gcgtattcct ccatggtagc aggcgtattt agagatcgta
    42601 tggttagata tgaacagaaa tacgttcata gcgcatatgg gctattaaaa attcgtactg
    42661 atggattgta tttcagatcc gaagtaccag agtttgaaga gctgtataaa cttggagtag
    42721 ttaagaaaaa agttcataca atatccaaag aagaagtcga aaaagcttta gaatttaaaa
    42781 acaaaggatt tgaaaataag ggctcctttg ggaaatctaa agatgaagtt aagggtgttg
    42841 tgatagacga tgatttcgag tttgattttg actaaatact ctttggaaaa gatggtagga
    42901 ggtaaatatg aagaagaaaa ttgtggaagg aaatgtaggt gttattattc taaaagattc
    42961 aactgactat gctaaatcaa tggcactaaa agacgaaaaa gttgcacgca tggataaaga
    43021 tttagttgaa tttctgatgg atgatacaga aagattaaaa ggggatcagt ttttgagttt
    43081 aatgaaagac aaaggcttaa acacatatgg tttatttgat tataagaaat tagctataga
    43141 gtgggtaaaa gaaggagaaa tattttttat tgaagaatgg gaaggtactg agaacttagt
    43201 tcttcatcag tatcttttga aagcttaatc taagtaaaac agttctgact agttatgctt
    43261 gtcagaattt caaaggaagt tttccataac catcatcatt caaaaataaa ggatttgaaa
    43321 ataagggttc ctttgggaaa tctaaagatg aagttaaggg tgttgtgata gacgatgatt
    43381 tcaagtttga ttttgactag atttttttga aaggtttaag agtaaacaag gtaagaacta
    43441 agatcatgaa gattgagagt aaagaagata gaggacgaat gtatgagaac acactatatt
    43501 tatttagaag ataaaattgt agatgaaatt ccggcaaaaa gtcgagaaca agctagaaaa
    43561 ttatttattg aaaaatacaa agagatcaat ggagatagtg aagttccaaa agtggtcgta
    43621 acagttagaa aaaggcaaac aaaaaagaga agtacgtttc atgtcagccc tgatatatat
    43681 aatcttatag agcgacatag aagtgaagat aatatttcta tctctcaata tattgctaca
    43741 gttattgatg aattgatttc aggaaagtat gactatgctt ttgattttga gggtgaaaag
    43801 gattacaaaa gtgttgctgt ctttcaatct gattttgaga agctaaaaaa ctatgctggc
    43861 aggagaaatg ttaattttgc aagactacta gaagagttct actccgaaga gttgggagta
    43921 ggaaatgaat acaagagaga aacttatgcg aaattgtctc ataagttatc ccaagcgctt
    43981 aaagaagtga cagaagttaa agcggaacta gatgctaaac ttgaagaagt gaaaaaatat
    44041 caaacagaga ggaagaacaa catgaagaat caagtggaat ttgacgaaca gaaagaattt
    44101 gaaaaagcaa gaaaacgcta taacaaaatt atgaatgaac ttagctatga acacttaaca
    44161 gttcatgaat aattgagtga gggtacagaa aaatatacga tcgcagatat ggttaatgaa
    44221 gtggaaactc ttttagcttc tttctttgaa aatggtcacg taaacgatga atggcgaaaa
    44281 gaagaaccta aaagggttaa cgcttatatt gctcgattaa aaaggtttat tgataaatat
    44341 aaggagaata gtgacaaatt ttctaaagat aaataaggag agagtgtgat tacatttgcc
    44401 agaaatcgaa ggaatatttt cgccaaaaat aggtaaaaaa cagttagatt tcagcagttt
    44461 tccgagcgta aatagagatt ataatctagg tgatgaggta cagatactaa atattgattt
    44521 caaagaacta gacttcgctg ttgctgtttc caacaaaccc aaggcattgg aacgagtgaa
    44581 aaaaatatac caagagaatg atcaaaatat caaaaatatg atcaaaaagt atagacgaga
    44641 taattcaaaa gttgaagacg ttttattcaa cggtacggca aaacatgatt tgaatgttta
    44701 tatggcatta ggagtggctt tgtactgtaa ttcaattaat cagacagata ttttggttaa
    44761 tatcgtgagg aatagctatc aaaaaatatt aaaaataagt agcgaaacaa acccttatta
    44821 tgcaatgaaa tatcttgggg ataatttatt aaatgataaa aaattgatgc acaacactga
    44881 agagctgtta tctaatttgg ctgcgattaa ctttctattc aaaacaggtt ctgaagatta
    44941 ttttatagat aacgtactaa aaggtgctta cggaacagca ttttatccgc tttacaatat
    45001 gaaacagcat aaagccgaac aaaaggataa caaacttgaa attaaaaaga tgaaagaact
    45061 attaggtata ggatttgtaa aacccaattc aaaagtcact attgcttcgt tagcaactac
    45121 taacaatgat gggaaaatag taaatgggtt tgacgattca gatatagata tattgtcaaa
    45181 atcatatttt tctttgtatg gagattttgc agatttgatg ggtattgata gttacttagt
    45241 caataatttt gagatcaagg gtagcgagct gaatgatatt gtgtatttcg ttttaatctc
    45301 tctatatgca attgatcaga ataccgagta ccgacaaatt gactatttgc tagtttttta
    45361 tagtttgtta tatcagttcg ttttaactcg gttgtttaaa aatgctaagg aagaattgat
    45421 cctgaattct gattatgaaa tagcaaaaca aattgcaagt attagaaaag aaaacaaatc
    45481 tgaagtaatc aaattaagaa aagaattaag tattgcgagt aaagaaaacg gtcggttaga
    45541 atctttagtc aaatcggcaa aaaaagaaga ggaacttttg aagcaagaga ttaaagaatt
    45601 aaaaggaatc agaaaagaac ttgaacagct gaggtttgaa aataaagtat taaagcaatt
    45661 gcaggagcaa gaacatagac aatcattaaa tggtaaaact gaagagcctt cactgtctga
    45721 aatgatagct tatctaaaac ataaaaacat tcttttagtg ggaggacatg taaattttca
    45781 aaataaatta actgaactat taccaaatat taaaatgttt gatgtaagcg aaaataatgg
    45841 aaagatactt aaaaatttga atacgtgtga tgcgattttt ctatatacag attacttgaa
    45901 tcatggtcta tattatcgtg ttatgagtga aatttctaat aaagataaga tattttattt
    45961 ggataatcat gtgaatatga acttaacaat taaacgtatt tacgatcttt tatcacttat
    46021 ataaagagag aagtgataaa taggacacaa aatttggaaa gtaggtaagt cactatgaga
    46081 gaactaactt tatcttctaa ggaattagaa aagaaaactg ctttattaaa cgaaatattt
    46141 agtgctgatt gtataatcca aagtttaaaa gaaagttcat tttcaaaact aacagatcag
    46201 gaaaaaattt cttatatgct aagtttagat aatctaggaa ctaaatatga tgaatcagca
    46261 agtagcgata agcttttgat tgaattagta tcaagtctta gtagttttgg aaaaatgaaa
    46321 agatttaatg tgatattaga aatttttgct tggttaatcc cttcatttat ttggtttttt
    46381 tatattttca tagttgaatc tgagttaata gccaaggtct ctcttggact gttaattccg
    46441 atataaatag gttcagcaat ttactttaat aacttgtata cacctattca aataaaaaag
    46501 cagttattac atgaaggatt aagtggtaat atgttaaaaa gaattgcatg ggataaagat
    46561 aataaaacag atattgagct taaagaatat aaatacaatt atttctcgag atgtatagat
    46621 agaaagttac tgtttaaaaa agaaggatta gaatttagtt ttgatgaaga tgaatttgaa
    46681 aaattagtga tggactggcg taagaattta ctggatacgg tacaattcta aaagcaattg
    46741 aggtcgaaat tccgatactt gaatcatgat ctatattatc gtgttatgag tgaaatttct
    46801 aataaagata agatatttca tttggacagt catgtgaata tgagcttaac aattaaacgt
    46861 atttatgatc ttttatatgt ttataaacat taatgaggtg ctaaaattga caacaataac
    46921 tatgacaaaa aaaatagaag tatatgttga tggatcacaa gaagaaaggg attccttttt
    46981 tgattttttt tggaaaaata gtagagaata tgtaaaagcg ttgaatctgg tatataaaca
    47041 gctaatgttt gaagagttga taaaagatgc aattaaagaa atggatcaag gttatgctga
    47101 gagagaagaa agtattcaaa atcggattga aaagttagca tatactgatc caatagatca
    47161 aaaaaaactt gataaagcaa aagctgaatt atctaaattg agaaatgaaa aaaataaaga
    47221 agcgagagaa atattaacgc aagcgatagg gttgaagagt caaacgagaa cacgagatgt
    47281 agcaaaaaaa ttagactttg actttggaga ttttgttgat tccgcaaata tgaaagctag
    47341 taaagatttt ggcaatgatt ttatcggaat tgtgaccgga caaagaacgc ctagaatata
    47401 taaaaataga aacaaatatg gattattacc ttttagaggt cgagatatta aaatccataa
    47461 agatgataag ttttatattt atttacctaa aggctttagg tttaaagtga atttaggtag
    47521 caagccaaga aaagcaagag atgttgcttc agttttacaa cacattatgg atggcgatta
    47581 caaattaaat caaagtaatc ttatttttga tggaagaaaa ttatttttta atctaacaat
    47641 ttcttttgaa aaaagctata atgaaatgga attcaagaaa ggtaatgaat tgatcgtaaa
    47701 ctttgcagat ttgtgtagcg gtgaatgttt aattaatgat aaatctgtaa tgtcttttgg
    47761 tgatagccaa tatataagaa acttcaaaag taaaatttta gcaatgaaat caaaagaaca
    47821 aagccgagga gtcttttcta agggcggtca tggtcgaaaa agaaaattag atcaagatcg
    47881 atgggaagca ataaagaaaa gagaaagtaa ttttgttaaa acttataata atcaatgttc
    47941 tgcaaaaatc gttaaaactg ctattcgcaa taaagctcaa attattcgta tcattgaacc
    48001 agataaggct tatggcgaat gggcttacta tcaattgaaa gaacaactag taaacaaagg
    48061 aaaaagatat gggatagaag tcagaagtta gtaaattaaa caatcgttga tttggcaacg
    48121 aaatagtgag ggaaaatcca ctcactgaag ggtaaactcc gtcaagttgt gtgaccagac
    48181 ggaaggacga atgttgttga ggttttagaa ccatataaaa cagcatgttt ctcaaatttt
    48241 taggataagg gaaattgcta gcagtttgtt ttagaaccat ataaaacagc atgtttctca
    48301 aatgagtact ttaaattaat tgatggcgtt cctgctttag aaccatataa aacaacatgg
    48361 atttaaaaca agaagtaagt cagttctcct tttactttag taaggaaaaa taaagtattc
    48421 tcaataaaac ttaaaataag caaacctttg ttttaaaatg attgtcaagt taaaaaaatc
    48481 tgggatcata taaaatagta tagttctcaa atatgattag aaaccctatt aaagagcaat
    48541 attaagccaa cttacttaaa tcgtttaatt aagaacaata atctctttta gtcagacttt
    48601 tagtctgact tttttgtatt tccaaaattt attctttaca aaaacgaaca tacgtttgta
    48661 taattacttg tgaatggggg aataaaaatg tttgattaca gtagagaacc ggtgaatgac
    48721 tattttttaa tcgacatgaa gtctttctat gctagcgtgg aatgtattga acgaaattta
    48781 gacccaatga ctacaccgtt aattgtcatg agtagatcgg acaacactgg ttcaggtctg
    48841 actctagctt cttcacctac tgcaaagaaa aaatatcata ttactaatgt tagtagagct
    48901 actgatttac cttatccatt accaaaagaa cttcatattg ttccaccacg aatgaactta
    48961 tatataaaaa aaaatatgga agttaatcag atttttagaa agtatgtcgc agatgaagat
    49021 ttattgattt attcgattga tgaatcaatt ttaaaagtga caaaatcctt aaatttattt
    49081 actatataaa ttgagttaaa ttgtattcgt ttttcctcct ataggcgtat actaaagaaa
    49141 acacttgagg agtggggaac atggaaacag aacgccaaat ccgtgaattg gaaaaagcga
    49201 tgaatacgac agacaaccgc cggttgtacg agcgtttcct ggcagtcaag ttggttcttg
    49261 aaggccacac ccggaaagaa gccgggcaca ccatcggccg cgacgagcat actgtcagcc
    49321 actatgtgaa aaactactgc cataatggaa tccaaggttt agtctccaaa aaacaaagcg
    49381 gacgaccttc acggctgaca gatgaacagg aagcggaact ggtccaaatc gtcgcctacc
    49441 acactccgga ggaagtaggt ttcaaatccc gtgccaattg gacattggcg attgtgtgtg
    49501 acctgattct ccgggaatgg agttatggat atacgcaaaa aggcgtggcg gacctccttc
    49561 accggctagg actaagctgg acccgtccga cgtataccct caaaaaagcg gattccaaga
    49621 aacaacaggt atttttggaa gaaaccttcc cgagcctaaa aaaaaattgc tgaatagcga
    49681 tattgaccac ctcctattcg aggacgaaac catgatccgg gattaccaag ccattggctg
    49741 cacctggttt ctccgcggcc accagcgaaa aatccccact tatggacaac acaaaggggt
    49801 aaaattgata ggcaccttgg attatgaaac cggtcggatc atttgtacag aagaaggggc
    49861 atacgacgca gcggccttcc tccgttttct ggagcggacg ttgcgggaat accccaccgg
    49921 aaaaatcgtg atggtattgg ataatgccct tatccaccac gccaagctga tccagtcttt
    49981 tcttgaagaa aacgctaggc gcctggcact catcttcctc cctccctaca gccctcagtt
    50041 gaacctaatg gaaggcgttt ggaagtggct caaggaatcg gtcatcaaca atgttttttt
    50101 tgaccacgtc cagaaaatca aacagtcggt ccgcggtttc ttagccgatg taaacgagcg
    50161 tccccttgag gtgattgacc gactgtgcgt gcggatgtaa agtatttaat tcaacctata
    50221 tagttcagga acaagaagcg agagaagaag agaattagct aaaataatca aagatgagat
    50281 tcagaaagaa acaggtctaa tagcaacagt cggaatagga gataacccat tattagctaa
    50341 acttgcactg gacaatgaag cgaagagtag taaagaattt atagctgagt ggacttatga
    50401 gactgtacct gaaaaaatat ggaaaataaa cgagatgact gacttttggg gcattggatc
    50461 acgcatgaaa aaaagattga atcatatggg aattatgagt atagaagatt tagcaaattg
    50521 gaatccctac acaattaaaa gtcagttagg tgtaatcgga ctccagttat atttccatac
    50581 caatggaatt gatcgtacgg atattgctat tccaccagaa ccaaccaaag aaaagtctta
    50641 tgggaattca caagttctac caaaagatta tacgaggaga gaagaagtag aactagtagt
    50701 caaggagatg gcagagcaag tagccattcg aattagacaa cacaattgca aaactggttg
    50761 tgtacgctta gcaattggta cgtcaatttt ggaagaaaaa tcaggtttct cgcaccagat
    50821 gaaaatacca attacagata atacgaaaga attacaaaat tattgtcttt ttttattcaa
    50881 taagttttat gaggggcagg aagtacgaca tataggagta acttatagca gattagtata
    50941 cacagattcc ctacaattag atttatttag tgatccaaga aaaaagattg ctgaagaaaa
    51001 tttggatagg attattgata agattagaca aaaatatgga tttacagcta ttatacatgc
    51061 ttcatctatg ttagaaggtg caagaagtat tacgagaagc actttaatag gaggacacgc
    51121 aggaggatta ggaggtttgc ataatgattg aatataacga tagaggacgt ttaaaatggt
    51181 cgggatttta tttgtctgat catactgaaa gaatcaatgc agacaatgta caacgtgcta
    51241 atcataattt ggcaaaagaa caaatgacga ctgaagagat tgcgaaaata ctgagaactg
    51301 ctgtcataaa aaatagaccc gtctgcattc aaaaagagga acgaaacgct gaaggttact
    51361 atccagatga tgtagtagga aaaattattg gatatgacga gcttggtgta tttgtggaag
    51421 aagaaaaagt tcactatgat gaaattagga atgtttcttt ctcggaatta ttaaaatgga
    51481 gtcagatatg aacattatta aaaaatacga attcggttat attacgtatg aacagctaat
    51541 agaggaatta tggggatatg gtcaacaatt aattaatgaa gtggggattg attgcttttg
    51601 tttctatatt gaatccggag caggatacca taagaacaga tactatatat ttccatatcc
    51661 accaaaatag tctcttagat atttttaaat tttctccaaa tactttcaat tattgtgaaa
    51721 tatttccctt taattaatca aattttttat aaaagtaata tataaaataa attgcttgaa
    51781 gtattatatt tagatatcat aatttatgga agaaaaatta attaaaaagg atgagattat
    51841 aatggggtta ctggttccga gagctaatac ttatactata cctttaacga aacgccaatt
    51901 aattgctaaa agatatcaaa ggattactag agccatcaat agagagtttt ggaattctga
    51961 aagtgatact gctcacagtt tatacgtagg ttcttatggg agaggaacgg caattagtac
    52021 tagtgatata gatataatag ttgaattacc gatggcagaa tttgacagat tcaaaaatta
    52081 tttatcaaat ggcccgtcta agttattaca agttataaaa aacgcatttc aggaaatact
    52141 accaaatagt gatattagag ctgatggaca agttgttaaa ataaatttcc atgatggaat
    52201 caaatttgaa atagttccag cttttaatga aaaagattat tggggtgagt caaaagggtt
    52261 tatttatcca gattcaaaca tgggagggaa ctggaaagct acaaatccca aaaaagagca
    52321 agaagccatg aaattaaaga atacaaaaag taataattta ttatatgcta cgtgtaaaca
    52381 ttttcgacat gtacgagata cagaatttac gagttatcat ctttcaggaa tagtaattga
    52441 cagtttcgta tatgaggcta tgggaaattg gaaattcgtt gaaaataaca gtgggggtca
    52501 aaacattagt tctgtatctt atgagacagc tttattagaa tactataact cacataaagt
    52561 tatgggcggt ttaaatttat actctcctgg aagcaatcaa tttgttaatt ctgatagtag
    52621 tatcatatgt ttagaaaaag tattaaaaaa aatagcttta taaagtttta tggaggaaca
    52681 acatgggaga cgaaaaaaag cgcttggaag ttcaattacg tgaagcatat ggacgagtaa
    52741 cgtatactta caccactcat ttaaagcaag ccgataatat tatttctgac aataaaattt
    52801 taaggtgtct tcaaattggt ttgtcagccc ttactactgg aggggtactt agtaccatta
    52861 ttactgataa tagtgagtta acctttgttg ctggattatg ttcaacaatt tctcttggat
    52921 taaacttata ctttaagaat tttgatcttg ctgaagaagc taaaaatcat caaattgttg
    52981 ccgataaatt atggttgatc agagaagaat acgtaagctt actaacagat ttaaatcgtt
    53041 taagtgttga agatattgtg aaaaaaagag atcaattaat gaacgaaact catgaagcat
    53101 ataaaaatgc ccctaaaaca aatagtaaaa gctatgaatc agctcagaaa gcattaaaat
    53161 ctgaagaaga gcaatttttt acagaagagg aattggataa gatgttacca gagcatctta
    53221 gaaaaaagag ttctaaatat tgaactcttt ttttatgctt aaaattctct tgtaattttt
    53281 ctattcatct atatttaaga agaaatatga tgatagaaac atctcctaaa gccaccgcaa
    53341 gccgttctaa gcatagctta gcccgacatt gctagatatg ctcatctcac catgaacgtt
    53401 tcctaaagcc accgcaagcc gtcctagcca ttgcctagtc cgacatcgct agattagtgc
    53461 atctcgccat aaaagttttc taaagccacc gcaagccgtt ctaagcatag cttagcccga
    53521 cattgctaga tatgctcatc tcaccatgaa cgtttcctaa agccaccgca aaccgtccta
    53581 gccatcgcct agtccgattt tgcttgatcg gttccatttc tgtttattta gtgggtcaac
    53641 accgtaatct taaatagcca tcgcctattt aagattacta ggtctgcttt gaaggtaaaa
    53701 agtctttcat tcttcaagac ttttaggctt tcaagctacg cctgaaagca ttgaaattca
    53761 tcgctcttta tttggttttg ccatttataa ttccttacgc ccattatctt tttcgcctgt
    53821 cataccttgt cagaagtgtt tagagcttat ctcatctttg gattaataca agtggcgtaa
    53881 atttttttct aaacgcaagc gttacgaaaa taatttactt aaacacttgt attaatccgg
    53941 cagataagaa cgcattctaa tcactcccga caaggcaaga caggcgaaaa agataaataa
    54001 atgaacgaaa ggaagaaaca taaaatgcaa aaccaaatag cgatgaagaa aaaaccacct
    54061 ccctctaaaa caatccaaac aaaaaagaat tttgaaaaac caaaaatcaa aaacagaaag
    54121 aagcgttcaa catgagagat agaattttag aagttaatca agaaatggta aacaagttaa
    54181 caaatatcag tgggaactat gaaaagtacg atggtacttt acttgataac tatatttttc
    54241 acgatacaca aaatatcaga attggcagaa gtaaaccgag agcgttcatt ctcatcaaag
    54301 agaaatattt gaatgaatgg aatagcacct atgaaatggt tatgactgat aactttgaaa
    54361 aggtattgga tttcagaaat gctttgttgg gttctgatat gggaaatagc agtcttgaat
    54421 ctattgaagt tgaaaacaag accgagaatg aaggtgaagg attgattaag aatgtcttga
    54481 aaatcgaaca aaaatatatc agtgaagata gaagttttta tagagtcaca agctcggttg
    54541 gtctagcaaa ctttgctact aacttaattg gaaacaatgc tagtgaatct ttgctagtga
    54601 tgtgtctgaa tacaaagaat gaggtcattg cttatagcga agttttcaaa ggtggaatta
    54661 atcaatcagt agcgatacca agagagattt ttcaactagc tttgctaaac aattcagcaa
    54721 aaatcgcagt atcacataat catccgagcg gatatgaatt tccaagtgaa aatgacaaaa
    54781 gttttactac gaatttgaaa aacgcaggaa aaacaattgg tattgaattg ttagaccata
    54841 tcatcgtaac aagtaaaaac acaagctatt actcatttca agaaaatggt tctttataaa
    54901 aattagagaa aagaggaaaa caagatgggc gaaagaacac aagcgttaat tacagtcaaa
    54961 tatggtaaca gcaaaacgaa agcaagcgtg tcgattcatt atcagtgggg gtatggtcga
    55021 tatatgctga tggacgtatt gaatcaagga atttatttaa tcaataaagc atacgactta
    55081 cgagataaat caagagaaga attagcaaaa ggaatctttg atagaagtac aggagttatc
    55141 aattttgtca cctatgaatc tggagtgagt gcttatgatg aaacagggtt tggtgggcgc
    55201 tatgaacctt atcaagaaac gattgaagat gtgatgaagt tttcagataa caatgatggc
    55261 tatgctcatt tagagatggt gttcgatgaa aatggattta gtctagatga taaaaccaga
    55321 ttgcgattgt ttgattttga gggtcaacag ataggactaa acaagttttg tgaaagcgga
    55381 aaagagtttg ctacgaaaga ttttattaag ggatacagat tattgctaga aaattatgga
    55441 ataaacctag aagaagagag cgtgaaataa gtgtttgaaa aaagaaaaga ccagttccct
    55501 aatttagaag cgaaaagtca aaaagtgatt gatggtgaaa tgattgaatt attccaaaaa
    55561 agttatggaa ccatagaaac taccgcaagt tgcaaatact actttcaagg aaagagaaac
    55621 acgtttaaag gctttgccga ttctgatgaa gaattggcaa agaaaatcat tgattggctt
    55681 gtcagcagtg aacacgtagc aagagaagat accgttagaa caacgattaa tggggaagtc
    55741 ctaacaggta ctagatgtgt ttgttgtaat catgaatttg tagaagatga aggttgctac
    55801 cgaatcaatg aatatggtga ttttatttgc cagagttgcc acgagataga atttccaacc
    55861 gaaagaagtt ggtttgaata catgctacaa gattatgaga tggaaacaga aaatggtgaa
    55921 gtagtttttt gtaccaaaga ggaattgagt aagagaagcg atgatgaaat tgaagattgg
    55981 tgtgtgtggt tagtagggac agatgattgc gttgcatatt acacaacagc agaataggag
    56041 tgtgaatcag catggaagga atggatttta tagatcatga agatttgatt gattttggtt
    56101 atacatggaa aggaatggta ggtattagca gaagtcttgc taatgccttt tacgaaagaa
    56161 attatgcagt ctatgtcctt tatgatgaca atacagaaag ccttgttgat gaagagtata
    56221 aattggattt agagaatgtt ttatatggga tagaaaaaga agatttagca aaatatattt
    56281 tttcatggtt gggtcaataa acgaaagagg gtagcaacat gacaaaattc aaaagtaaag
    56341 gtatgcaatg gtgttcttat tattatgttg ggaatgatga agagcttttg agaaaagcca
    56401 aacaaaaagg ttatccagat aagatgttaa aacagattgg ctattacatg ccagaagaga
    56461 gaatagaaaa agaatcttgt aaggttcttt ttgatagtga acagctatta gttttgttaa
    56521 ctcaaaataa attgatttgt caatttgaaa ataattaata tggggtgaag aaccatgaat
    56581 gagaataaga tggtattaag tgaatacgca agattgagaa ccattaattg gttgaatggt
    56641 atgcaaagta gtggcgcttt tgatggattt gatgaggaga atatggactt tgaaagttta
    56701 tcgaatgagg atattagata ttattttatc gaatggtatt ttacagaacc agatgaagag
    56761 gtggaagatg aaccagaatt aattttagaa cgtcaaagaa ttttattcag tgaacaagat
    56821 agtaagaggt tgtatggttt atatgactta caactgaaag gattaaaagc gcagtatgtt
    56881 gctgatagtt acgatgatat ggtagaacag ggggcagata gggttgtcac ttattcagaa
    56941 gatgatgaag aggaatggga aaactattca gatgatgaga tatgctttaa tgatgggtat
    57001 atgcctattg aaatcaccga agaagaatat gataaagtgt cggatagcga tgagattggt
    57061 atgtgtacgg ttgtaagtgg attggatata gatgtccaaa gagtagaggt tgcataccag
    57121 aagatgaaag aacgtataaa aagtaaagta gaatcttgat ttgattggat tgtttgcaaa
    57181 gtagctaatt aagagtataa tataatcata aatgtagtta atggatataa taatgagtat
    57241 attatactca aaagaggtga acgaaatgaa ggtaaaaaat ccaaaagaaa aaagcagaat
    57301 tcaagtcgga atagacaagg atttaaaaga aaacgcagaa atgatattgg aagagctagg
    57361 gttaaatcca acaacagcaa tcacaatcct ttataagcaa gtggtcgcta gaggtgagtt
    57421 tccagtagag ataaagctaa gcgaagagga aaagcaagga atcagattgc aacagctaac
    57481 tatggatatg ccagttgatg ttctagatac agatgaaaag ttagaagagt ggttcaatga
    57541 agcctaatga gatagtaacg gtctatgttg catttacaga taaaaatggt ggtaaaagaa
    57601 gacctatttt ggtggttagt gataaagaag atagagtaga attttttgga atcacaagtc
    57661 aatatgagaa taaatcagac caaataaaga gagtgtattt tcctattgca gaatgggaaa
    57721 aagtaggtct aaagaagcaa tcatggattg acgtagggtc tttaaaggct attcccaaaa
    57781 gccgagagaa catatcattt aaaaaggttg gtatgctatc agctattgat acgaaaaagc
    57841 taaataggtt tatcgagaga ttacaaagaa aagtctaaca aggcttttct ttttttgttt
    57901 atatgtatat taagatatac gtttatataa acgtatttat gtatattaaa atacacgtaa
    57961 atatatacgt gattataaaa attaagaaaa tattaagtat tgttaaatag tgataattag
    58021 taatatacga attataagat acattttata tttaatgtat gtaaataaat aaaatgactg
    58081 acggatattg aatagtaata aataacaata attcagacgg atacagtgag tgaagtagct
    58141 tgctacgaac gaacaggcag aatgaaacgg tagtttcatt agagcaagtc gcttgcgacg
    58201 tagcgttacc actgatgtaa ctggcaagtt acatagagag agtttgcttg caaacgaacg
    58261 ttacccactt gaatagaaaa caaaaataac atattagtga attttgaata ggagccacaa
    58321 ctcaaccaac cgcttgcggt gggtgagtcc cacggaggaa aagacgaacg aacggtcgcg
    58381 tagc
//
LOCUS       DADQDV010000011        55502 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.011, whole genome shotgun sequence.
ACCESSION   DADQDV010000011 DADQDV010000000
VERSION     DADQDV010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 55502)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55502)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55502
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.011"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            558..3197
                     /locus_tag="J8S10_000719"
     CDS             558..3197
                     /locus_tag="J8S10_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAZ9629325.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(3365..4063)
                     /locus_tag="J8S10_000720"
     CDS             complement(3365..4063)
                     /locus_tag="J8S10_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HAZ9629326.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            4281..5426
                     /gene="tgt"
                     /locus_tag="J8S10_000721"
     CDS             4281..5426
                     /gene="tgt"
                     /locus_tag="J8S10_000721"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010769586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HAZ9629327.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            5523..5903
                     /gene="yajC"
                     /locus_tag="J8S10_000722"
     CDS             5523..5903
                     /gene="yajC"
                     /locus_tag="J8S10_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HAZ9629328.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            6208..8805
                     /gene="adhE"
                     /locus_tag="J8S10_000723"
                     /gene_synonym="adhC"
     CDS             6208..8805
                     /gene="adhE"
                     /locus_tag="J8S10_000723"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HAZ9629329.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            9034..10140
                     /locus_tag="J8S10_000724"
     CDS             9034..10140
                     /locus_tag="J8S10_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HAZ9629330.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            10157..11185
                     /locus_tag="J8S10_000725"
     CDS             10157..11185
                     /locus_tag="J8S10_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HAZ9629331.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLEGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            11191..11670
                     /locus_tag="J8S10_000726"
     CDS             11191..11670
                     /locus_tag="J8S10_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HAZ9629332.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            11686..12981
                     /locus_tag="J8S10_000727"
     CDS             11686..12981
                     /locus_tag="J8S10_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HAZ9629333.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            12992..13816
                     /locus_tag="J8S10_000728"
     CDS             12992..13816
                     /locus_tag="J8S10_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAZ9629334.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPETP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            13981..14880
                     /locus_tag="J8S10_000729"
     CDS             13981..14880
                     /locus_tag="J8S10_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAZ9629335.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(15006..15875)
                     /locus_tag="J8S10_000730"
     CDS             complement(15006..15875)
                     /locus_tag="J8S10_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAZ9629336.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            16028..17488
                     /gene="rhaB"
                     /locus_tag="J8S10_000731"
     CDS             16028..17488
                     /gene="rhaB"
                     /locus_tag="J8S10_000731"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HAZ9629337.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            17485..18741
                     /gene="rhaA"
                     /locus_tag="J8S10_000732"
     CDS             17485..18741
                     /gene="rhaA"
                     /locus_tag="J8S10_000732"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HAZ9629338.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            18755..19600
                     /gene="rhaD"
                     /locus_tag="J8S10_000733"
     CDS             18755..19600
                     /gene="rhaD"
                     /locus_tag="J8S10_000733"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HAZ9629339.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            19602..19913
                     /gene="rhaM"
                     /locus_tag="J8S10_000734"
     CDS             19602..19913
                     /gene="rhaM"
                     /locus_tag="J8S10_000734"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HAZ9629340.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            19995..21146
                     /gene="fucO"
                     /locus_tag="J8S10_000735"
     CDS             19995..21146
                     /gene="fucO"
                     /locus_tag="J8S10_000735"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HAZ9629341.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEVSVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            21273..22031
                     /locus_tag="J8S10_000736"
     CDS             21273..22031
                     /locus_tag="J8S10_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HAZ9629342.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIQTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            22131..22775
                     /locus_tag="J8S10_000737"
     CDS             22131..22775
                     /locus_tag="J8S10_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HAZ9629343.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            22782..23789
                     /locus_tag="J8S10_000738"
     CDS             22782..23789
                     /locus_tag="J8S10_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HAZ9629344.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            23805..24647
                     /gene="kduI"
                     /locus_tag="J8S10_000739"
     CDS             23805..24647
                     /gene="kduI"
                     /locus_tag="J8S10_000739"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HAZ9629345.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            24667..25470
                     /locus_tag="J8S10_000740"
     CDS             24667..25470
                     /locus_tag="J8S10_000740"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HAZ9629346.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(25719..26783)
                     /locus_tag="J8S10_000741"
     CDS             complement(25719..26783)
                     /locus_tag="J8S10_000741"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HAZ9629347.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(26780..27865)
                     /locus_tag="J8S10_000742"
     CDS             complement(26780..27865)
                     /locus_tag="J8S10_000742"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HAZ9629348.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            complement(27878..28855)
                     /gene="mvaD"
                     /locus_tag="J8S10_000743"
     CDS             complement(27878..28855)
                     /gene="mvaD"
                     /locus_tag="J8S10_000743"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HAZ9629349.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            complement(28848..29792)
                     /gene="mvk"
                     /locus_tag="J8S10_000744"
     CDS             complement(28848..29792)
                     /gene="mvk"
                     /locus_tag="J8S10_000744"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HAZ9629350.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            30114..30767
                     /locus_tag="J8S10_000745"
     CDS             30114..30767
                     /locus_tag="J8S10_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAZ9629351.1"
                     /translation="MIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFYAN
                     PEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEVRV
                     YDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYDYY
                     KELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVAI"
     gene            30852..31757
                     /locus_tag="J8S10_000746"
     CDS             30852..31757
                     /locus_tag="J8S10_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HAZ9629352.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(31759..32391)
                     /locus_tag="J8S10_000747"
     CDS             complement(31759..32391)
                     /locus_tag="J8S10_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HAZ9629353.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            32711..33235
                     /gene="infC"
                     /locus_tag="J8S10_000748"
     CDS             32711..33235
                     /gene="infC"
                     /locus_tag="J8S10_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HAZ9629354.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     gene            33307..33507
                     /gene="rpmI"
                     /locus_tag="J8S10_000749"
     CDS             33307..33507
                     /gene="rpmI"
                     /locus_tag="J8S10_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HAZ9629355.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            33560..33919
                     /gene="rplT"
                     /locus_tag="J8S10_000750"
     CDS             33560..33919
                     /gene="rplT"
                     /locus_tag="J8S10_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HAZ9629356.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            34171..35508
                     /locus_tag="J8S10_000751"
     CDS             34171..35508
                     /locus_tag="J8S10_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HAZ9629357.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAILCLITFLLYGNA"
     gene            35556..37685
                     /locus_tag="J8S10_000752"
     CDS             35556..37685
                     /locus_tag="J8S10_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HAZ9629358.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            37660..38349
                     /locus_tag="J8S10_000753"
     CDS             37660..38349
                     /locus_tag="J8S10_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629359.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(38757..39370)
                     /locus_tag="J8S10_000754"
                     /pseudo
     CDS             complement(38757..39370)
                     /locus_tag="J8S10_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
     gene            complement(39506..39700)
                     /locus_tag="J8S10_000755"
     CDS             complement(39506..39700)
                     /locus_tag="J8S10_000755"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629360.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(39750..40190)
                     /locus_tag="J8S10_000756"
     CDS             complement(39750..40190)
                     /locus_tag="J8S10_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HAZ9629361.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            complement(40194..41039)
                     /locus_tag="J8S10_000757"
     CDS             complement(40194..41039)
                     /locus_tag="J8S10_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HAZ9629362.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            41188..42606
                     /gene="pepV"
                     /locus_tag="J8S10_000758"
     CDS             41188..42606
                     /gene="pepV"
                     /locus_tag="J8S10_000758"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HAZ9629363.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            complement(42663..43610)
                     /locus_tag="J8S10_000759"
     CDS             complement(42663..43610)
                     /locus_tag="J8S10_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAZ9629364.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(43833..44183)
                     /locus_tag="J8S10_000760"
     CDS             complement(43833..44183)
                     /locus_tag="J8S10_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAZ9629365.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            44383..45462
                     /gene="pepA"
                     /locus_tag="J8S10_000761"
     CDS             44383..45462
                     /gene="pepA"
                     /locus_tag="J8S10_000761"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HAZ9629366.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            45606..45926
                     /locus_tag="J8S10_000762"
     CDS             45606..45926
                     /locus_tag="J8S10_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HAZ9629367.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            45948..46412
                     /locus_tag="J8S10_000763"
     CDS             45948..46412
                     /locus_tag="J8S10_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAZ9629368.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            46617..47222
                     /locus_tag="J8S10_000764"
     CDS             46617..47222
                     /locus_tag="J8S10_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HAZ9629369.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(47261..48550)
                     /locus_tag="J8S10_000765"
     CDS             complement(47261..48550)
                     /locus_tag="J8S10_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HAZ9629370.1"
                     /translation="MDRKNVTPKMKKSKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            48978..49457
                     /gene="rlmH"
                     /locus_tag="J8S10_000766"
     CDS             48978..49457
                     /gene="rlmH"
                     /locus_tag="J8S10_000766"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HAZ9629371.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            49542..50051
                     /locus_tag="J8S10_000767"
     CDS             49542..50051
                     /locus_tag="J8S10_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HAZ9629372.1"
                     /translation="MNNNDRLLRLRYAIDLKDTDLIKAFELGGVPLTKEEAQAVLTKV
                     QDKNKDNAENNVYEKTINNQVFDAFLNGLILLARGPQKDKPIVDTPQKSKEIKYINNV
                     LLKKLKIALSMTTDDILDVFAEAEIYPSKGEIGAFLRKEGQRNFKPCGDKYMRNFLKG
                     LGIYNRRKV"
     gene            50151..50801
                     /locus_tag="J8S10_000768"
     CDS             50151..50801
                     /locus_tag="J8S10_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629373.1"
                     /translation="MNDEYKNDEDKMLFEEIENRCRLNFELRGKMSLIQQKKYLANKS
                     EFTLGHVEKLISDWISSRSEFTKIKQPIKFDMKKLLLNKSEIGNRDQYIRAKGQEIID
                     SLGEMRSYNYLYVTHRADGMVITVGKSSSNDIFLDGDLFYQLNTNHLSGTENIILRTE
                     YGNEIFAKYDEILKNYLDWAWIIPVESGDAKKLERLLGDELINKKVPILNYYSHRQ"
     gene            51252..52190
                     /locus_tag="J8S10_000769"
     CDS             51252..52190
                     /locus_tag="J8S10_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015081805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HAZ9629374.1"
                     /translation="MKIAIAGAGAMGSRFGLMLHQSGNEVLLIDGWAEHVQQIKEHGL
                     QANFNGKEVEAKLPIVLQSEVEKEDQVDLIILFTKAMQLEKMLQDIQSLIKKDTEVLC
                     LLNGIGHEDIIEKFVPMENIYIGNTMWTAGLEGPGQVKLFGSGSVELQNLGDGKEAAA
                     KKLADKLSESGLNAHFSDNIHYSIYRKACVNGTMNGLCTILDVNMAELGKTSTAHKMV
                     ATIVNEFAKVAAVEKIELDVPEVIAHCESCFDPETIGLHYPSMYQDLIKNHRLTEIDY
                     INGAISRKGKKYGVATPYCDFLTELVHAKEDSLNVK"
     gene            52203..53255
                     /locus_tag="J8S10_000770"
     CDS             52203..53255
                     /locus_tag="J8S10_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAZ9629375.1"
                     /translation="METSQKISPKIFLNKVLAGTATGIIIGLIPNAVLGAILKYFSAY
                     PFAVTIAQLAVIFQLATPLIIGGLIALQFGFDPMRMMVVAGASFVGSGVVKFTPDLGE
                     TGVYVGAGTGDIINTMLTASIAVGLILLIGNSFGSVSIVLTPIVVGVGAGLLGFYLFP
                     FVTAITSAIGSLINNFTTLQPLLMSILIGCSFAFLIISPISTVAIGMAIQLDGVSAGA
                     AAMGVAATTFVLVVNSWKVNKSGVTIAIALGAMKMMMPNLFRKPVILIPCLVSAVITA
                     IPVALFSISGTPASAGFGVVGLVGPLASLDAGLNGFLVVLCWLVIPVFAALITQFLCE
                     KVFKLYDREEVFKFLG"
     gene            53521..54156
                     /locus_tag="J8S10_000771"
     CDS             53521..54156
                     /locus_tag="J8S10_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HAZ9629376.1"
                     /translation="MIFLQKYGFYFLLLGVISDLSTPYILGLFYPKLNQMTTVISVFG
                     DVDSPVRRAFLVWSVVSGLFFVLSLPALYHLFIGTSKTLAILAVATVGLYGIGDCIFT
                     GLFSINTNESSWNLSTWIHNIGSGLGYAGFLLFPLLLVLLYRQSGQGTLSHFYLVLTV
                     ISLLIAGLYGLARIPSISQFAFFKQLGFFQRLSFFFNYLPMICLSFFQLRK"
     gene            54347..55138
                     /gene="msrA"
                     /locus_tag="J8S10_000772"
     CDS             54347..55138
                     /gene="msrA"
                     /locus_tag="J8S10_000772"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAZ9629377.1"
                     /translation="MLDVEQMEIDLYNIILNRNTREWERTQFEEAKEDLAKMSIKQVI
                     EKLEVNLRPLALRDNLTPDAMDFYLRITGESASAKAYDYAKHKITSPLYQERAIFAGG
                     CFWCMVEPFETKPGVISVLSGYTGGETKKPNYDQVSGGYTGHVEAVEIIFDTRQITYE
                     ELLEIYWQISDPTDAFGQFQDRGKQYRSILFVVNEKQRQLAEKSREQLIQSNRFSRPI
                     VTEIRQAKTFWPAENHHQQFYQKQPKRYKKIKHSHQLHLFFQRHR"
BASE COUNT        17619 a         9922 c        11894 g        16067 t
ORIGIN      
        1 aaaaagccga gctctcgata agctcggctt tcttgtacct cggaaggatt caaataaaca
       61 gaaatgattg taactttcca tcatacatgc aaagcacggt gttgaatttc ttcatgttaa
      121 acaaaaattt tgttttcgtt acatcttcaa catttgaaac atctcttgtt cctattcaat
      181 tttcagacgt ttacgttatt caattgttac gtatcgcatt acttcttgtt tcggatactt
      241 cgtgatccaa acatccatac gcattcacta tttataggtt tgtactctac acgcatgtct
      301 gggtgaaacc tgtacttcta acaactttgt ttgcttacac tgttctatcg agaaattctt
      361 ctgtctattt gatggtatcc tccttcctta catctatata atagcatcct ttggtagcgt
      421 ttgcaaatat aagcacttta aattttacgc tttcttaaca aataatcgat aagcccttta
      481 tttgaagtaa ataaaaaaag gatgttatag taaaataagt accttttttt gtacgaagat
      541 tttaaaggag gaataggatg gaagaataca agcagacaat agaagaagta aagaaggtaa
      601 cagaagcaga tccagatact gggttgtctt cacaagaagt ggatgaacgg cgaaaaaagc
      661 agggattgaa taaattcgat gaggcgccga aagaatcgat gatcaaaaaa ttctttcgaa
      721 gcttgtccga ttttacaacg atcatccttc ttgtagcagc ggtgatttcc ttttataccg
      781 catttgctac agaacatggg gatttatttg aaggactgct gatcatcgct atcgttgtga
      841 tcaactcggt attggcgatt gtccaagaag gaaacgcaga aaaagcactg gaatccttgc
      901 aagatatgaa taaacaaacg gcaactgtca tacgagacgg caaagtgacc actgttgagt
      961 cagagcaact ggtagtgggt gatattcttg ttttagagtc cggtgatgct atttctgccg
     1021 atgcccgttt gatcgaagca tcacaattac gtgtagaaga atcggcgttg actggagaaa
     1081 gtgaagcagt tgaaaaagat gcagcattta ttgctgaaga agatgagtca ttaggtgacc
     1141 aacttaatat ggtatttaaa ggatgtacgg ttgctgcagg tcgtgggaaa gcgatcgtca
     1201 ctgccattgg catggctaca gaaatgggta agatcgcgga tcttttgaac gaaaatacta
     1261 tgcaaaaaac acctttacag gtccgattga atcagctagg caaacgaatc agtatgatcg
     1321 ctttagcggc tgcggcttta gtatttgtga ttggtgaact gcaaggagaa ccactccttg
     1381 agatgttcat gacttcgatt tccttggctg ttgcagctgt accggaaacc ttgactgtta
     1441 ttgttacgtt gacacttgca tacggtgtgc agaagatggc gaggaaacat gcgatcatcc
     1501 gacagttgcc agcagttgaa acgctaggaa ccgctaatgt tatctgctca gacaaaacag
     1561 gaacgctgac acaaaatgaa atgcgcgtcc gccgggtatg gagcaaagaa gatgaagtaa
     1621 cgaatatcga agattcaatg acgaacagcg cgatggaaat attgaaaatg gctgcactat
     1681 gtacagatgt gacggtcgag caagaagatg acgaccttgt tatcaaaggt aatccaacag
     1741 aagtagccat cgtaagggct gttgaagaga attatcatac aaaggcagaa ttagaagaaa
     1801 aatatccacg agtaaacgag cttccttttg attctgaacg aaaaatgatg acaacagttc
     1861 accaaatggg cgaaaaatac atctcaatca ccaaaggagc attcgatgtt cttgctccgc
     1921 gctttagttc aggcgatgta gaacaagcgg cgatcgttaa tgatcgcttt ggtaaacggg
     1981 cactgagagt gattgctgtt ggttatgcta cttatgacga agaaccgcaa gatatttctt
     2041 ctgaagcact ggaaaaagac ttacgtttga ttggtctgat cggaatgatc gatccaccac
     2101 gtccagaaag taaaggagca atcaagcgag cgaaaaaggc tggcatcaaa acagtcatga
     2161 tcactggaga tcatgtggtg actgccagtg ccatagcgaa agaattaggt atcttgaatg
     2221 atccgtcaga agcactttca ggatcagaac tgcatcaatt atcagacgaa gaattagatg
     2281 cgcgtgtcaa agctctctct gtctatgctc gggtaacgcc agaagacaag atccggatcg
     2341 tcaaatcttg gcaacgtacg ggtgcagtcg tagcgatgac tggggatggt gtgaatgatg
     2401 caccagcgtt gaaagcaagt aacgttgggt gtgccatggg gatcacagga acagatgtgg
     2461 cgcaaagtgc cgcagatatg attttgacgg atgacaactt tgcgacgatc gtagacgctg
     2521 tcagtcaagg acgttcggtt tatcagaata ttcgtaaagc tatcaacttt ttgctaagct
     2581 gtaatatttc ggagatcttt attgttttga ttgcgatgct gttaggatgg ggagcaccat
     2641 ttacagctgt gcaactactg tttgtcaatg tagttgctga tggacttcca ggatttgctt
     2701 taggaagaga gccagcggaa cacggcatca tggatcagcc acccattccg aaaaatgaag
     2761 ggatctttgc tcgaggttta ttgcaaaaaa ttgccataaa tgcaggggtc ttcaccatcg
     2821 taaccttgtt tggttattat ttaggtagtt atgtcgatac tatcagccca tgggtagacg
     2881 caagtcagca tgtcggtcaa actgttgcat tcttgatctt agcttattca tcgattctgc
     2941 atgtgttcaa tgtacgcagc agccaatcga tcttcaaagt caatttagcg accaataaag
     3001 ctttggtaga aatggcgtta ctggcattag ctattacaac ggctgttgct ttgctgccat
     3061 ttacgcaaga actattcggc ctagtacaca tcagtttgaa tcactggttc ttggtaggga
     3121 ttttatctat cgtaccaatc gcggtgaatg aactgatcaa gttccatcga ttaccggaag
     3181 cagaagaaga ggaatgatta actgtttcta agttgatttt ctttttactg gaactataca
     3241 aaaaggaggt gtgacatgaa tgttgtcaca cctccttttt gctaatgggc tgaatgtttc
     3301 ttttactgcc tctcgataaa cggtgttctc ctgccacccc ctcggtcaca agtcacactc
     3361 tcttttaaat atcttttggc aattgttcat aaaatgctgc ttttgttgca gaaatgtatg
     3421 ggctgagcca tagataacca ataccagcag ttgctaatgc taagatatgc cagccgataa
     3481 atgaaagatc taaccagaaa agttgtcctt tataaccatc catcaatttt cgacttgcag
     3541 tgatcgtatc cagtacttta ggtgtttgtc ctgtttcttg gacgatatcg tagtaaataa
     3601 aatagctttg agaataagaa tagcttttaa tgattccagg aataactaat agcaaacccc
     3661 ataatgttgt aaagatcgag atcagcacag ctaagctgat cactccgccg ataaacaaac
     3721 ctttgaatcc acgaaatgca tctttgaatg gttcgatctg atctttttgt ccacgtaaaa
     3781 tatcaagata agtccaagaa ataccgctca tgaacaaagc gctaatgatg ctggaaataa
     3841 ttccgccacc gcctcctgaa ctaccgcctc ctgaagttgt cgcttctgag acgctcgctg
     3901 atccatcata tatggtggtg gcaaacaaga taataggaat cataataaga agaatagtag
     3961 caataccaat caatgtaggg attagattta gtaaaacagc ttgtccccaa cgtcctttta
     4021 gactctcttt tgcttggcgt tttaattctg cagaagattg catgattttt ccctcctttt
     4081 ctttaataac accaatatac catgtatcaa aaaatatttc tgtcataatg tttttctttt
     4141 ttttgttatt cataaaaaaa ggataaaaaa aagaatatta aataaagtag aaggaagccg
     4201 agggaacttg caaaaagcac ttgaaacgat tatgatggtg ggagttgtca agatatttta
     4261 tatagaaagt agggaaatga atgacgcaac ctgccattcg ctatcgttta atcaagaaag
     4321 aaaaacatac tggcgcgcgt ttaggggaat tgatcacgcc acacggaact ttccccacac
     4381 caatgttcat gccagtagga acattagcta cagtaaaaac aatgtcccca gaagagttga
     4441 aagaaatggg tgctggcgtt attttaagta atacatatca tttatggcta cgccctggtg
     4501 aagacttagt agaagaagct ggcggactgc ataaatttat gaactgggat caaccgattt
     4561 taacagattc aggcggcttt caagtttttt cattaagtga tatgcggaat atcgaagaag
     4621 aaggcgtgca tttcaaaaat cacttgaacg gttcgcgtat gtttttatca ccagaaaaag
     4681 caatcaacat ccaaaataaa ttgggctctg atatcatgat gagttttgac gaatgtccac
     4741 cattcgatga aagttacgac tacgtgaaaa aatcagtaga acgtacgtct cgatgggcag
     4801 aacgaggatt gaaagctcat gctaatccag accgtcaagg attatttgga atcatccaag
     4861 gagcagggtt tgaagatctt cgtcgtcaaa gcgcgaaaga tctagtcggg atggatttcc
     4921 ctggttactc aatcggcggg ttatctgtcg gggaacctaa atcagaaatg aatcgtgtat
     4981 tagaattcac tacaccgttg atccccgaaa acaaaccacg ttacttgatg ggtgtcggtg
     5041 ctgctgattc attgatcgat ggtgttatcc gtggagtaga catgtttgac tgtgtcttgc
     5101 ctactcgaat cgctcgaaat ggcacatgta tgacttctca aggccgtcta gtagtgaaaa
     5161 atgcgaaata tgcccatgat ttccgtccaa ttgatgagaa atgtgattgt tatacatgta
     5221 aaaactatac acgtgcctat atccgccatt tgatcaaatg tgatgaaaca tttgggattc
     5281 gtttgacttc ttaccacaat ttatacttct tgttgaatct aatgaaacaa gtacgtcaag
     5341 caatcatgga tgataatttg cttgaattta gagaagcctt ttttgaagaa tacgggttca
     5401 ataaagaaaa cgcaaaaagc ttctaaagga aaatctttta aaaattaagt aaaaaactag
     5461 tgttatcagc atttttctgc taaagtgttt tttgtagata cagaattagt gaggtgaaaa
     5521 aaatgggaac attaccaatg cttgtgatgt ttatcgcgct attagcaatg tggtttttta
     5581 tgtcacgttc gcaaaagaaa caacagcaag aacgtcaaaa cttgttagat agcatgaaac
     5641 caggtgattc agtcgtaacg atcggcggat tacatggagt tgtttcagaa atcgacaatg
     5701 acaaacggac agttgtttta gactgcgaag ggatcttcct tgagtacgat cgtgcagcaa
     5761 tcaaaacggt caaaccaggg actgtcgtaa caaatgatgc aacgactact gttgaaacaa
     5821 cagaagaacc agctgagaca gttgaagtaa aaactgaaac aacagaaacg ctggaagaga
     5881 cagaagagaa ggaagaaaaa taagtatcaa agcttattta aagacgaggt agggcagaaa
     5941 gatgtcctac ctcatttttt attcaaaaaa gaaagagata agagcatggg atatattgct
     6001 caatattgaa taatcgggtg tgtcatataa ataataataa ataactttat atatttttct
     6061 atacaaacac ctgtaaataa agcaatttta tatttaaaaa taactgtgaa aaaaatcaca
     6121 aaaaagtgtt tacatagaaa aataaatatt gtatgatata catgtgaatt atttaacaaa
     6181 taaccatgac ccattaggag gataatgatg gctaaagtaa tagaaaaaga aaaaacgaag
     6241 acaattgacg tacaagcaat gattgatgat ttggcagaaa aagcaaatgc agcattgaaa
     6301 gaaatggaaa gctttgatca agaaaaagta gaccatatcg tgcatgaaat ggcaatggca
     6361 gctttggatc aacatatgcc attagcgaag atggctgtag aggaaacagg ccgcggtgtt
     6421 tacgaagata aagcaatcaa aaatatgtat gcgtccgaat atatttggca taatatcaaa
     6481 catgataaaa cagttggtgt gatcaatgaa gatgtccaaa aagggttgat tgaaattgct
     6541 gaaccagtcg gtgtggtttg cggagtaact ccaacaacga atccgacttc cacaacgatt
     6601 ttcaaatcaa tgatcgcgtt gaaaacaaga aatccaatcg tttttgcttt ccatccaagt
     6661 gcccaaaaat cttctgcaga agcagcacga gtggtacgtg atgctgctat cgctgccgga
     6721 gctcctgaaa attgtatcca atggatcgaa catccttcga tcgaagcgac ttctatgcta
     6781 atgaaccatc caggtatcgc gatcgtctta gcgacaggtg gagctggaat ggtcaagtct
     6841 gcttactcta caggaaaacc agctttaggt gtaggtccag gtaacgtacc agcttatatt
     6901 gaaaaaacag caaaaattaa acgtgcagtg aacgatttga tcgtttcgaa aacatttgat
     6961 aatggaatga tttgtgcttc tgaacaagct gtgatcgtgg ataaagaaat ctatgcagca
     7021 gtaaaagcag aattccaagc acaccaagtt tatatcgtaa aaccagatga attgcaaaaa
     7081 ttagaagatg cagtgatgaa cgaaggaaaa tatgcggtca atccatcaat cgttggacat
     7141 tctgcgatgg aaatcgcaaa attggcagga atcagtgtac caaaaggaac gaaaatgctg
     7201 attgctgaat tggaaggcgt aggcccagat tatccgctat caagagaaaa actttctcca
     7261 gttcttgcca tgatcaaagc taacaacacg gaccatgcgt ttgatttgtg tgaaggtatg
     7321 ttgaatcttg gaggattagg acatacagca gttatccatt cagaaaacga agagttgcat
     7381 gtcaaattcg gtcttcgaat gaaagcttgt cgtattttag tgaatacacc atctgcagaa
     7441 ggcggcatcg gtgatatcta taacgaaatg attccgtcat tgactttggg atgcggttct
     7501 tatggtaaga actctgtttc tcgtaacgtc tctgctgtaa acttaatcaa tgtcaaaact
     7561 gtagcgaaac ggagaaataa catgcaatgg ttcaaattac cgccaaaaat cttctttgaa
     7621 aagaactctc tattgtactt agagaaaatg gaaaacgttg aacgtgtcat gatcgtttgt
     7681 gaccctggta tggtccaatt cggttactgc gatacagttc gtgaagtatt ggcacgacgt
     7741 aaaaatgatg tgaagatcga agtcttctca gatgttgaac cgaacccatc gacaaatacc
     7801 gtatacgcag gaacgaaact gatggcagac ttcaagccag atacagtaat cgctcttgga
     7861 ggcggttctg caatggacgc agctaaggga atgtggatgt tctatgaaca cccagacaca
     7921 tctttctttg gtgcaaaaca aaaattcttg gatatccgta aacggacata taagatcgac
     7981 aaaccagaaa aaacacaatt cgtatgtatc ccgacaacat cagggactgg ttctgaagta
     8041 acgccatttg cggtcatcac tgacagtgaa acacatgtga aatatccgtt agcagattat
     8101 gcattgacgc cagatgtcgc aatcgtcgat cctcaattcg tcatgtcagt tccagcatct
     8161 gtcacagcag ataccgggat ggatgtgtta acacatgcaa tcgaatccta tgtttcagtc
     8221 atggcttcag attatacacg tggattgagc ctacaagcaa tcaagttagt ctttgactat
     8281 ttagaaaaat cagtaaaaac acctgatatg gaatcacgtg aaaaaatgca caacgcttct
     8341 acaatggctg gtatggcgtt tgctaacgca ttcctaggta tttgtcactc agtcgcacat
     8401 aaaatcggcg gggaatacgg gatccctcat ggacggacaa atgcgattct tttaccgcat
     8461 attatccgct ataatgcaaa agatccacaa aaacatgcga tgttccctaa atatgactat
     8521 ttccgtgcag atacagatta cgcagatatc gcaaaattct taggtctgaa aggcgaaaca
     8581 acagaggaat tagtcgaagc tttagcaacg gctgtttatg aattaggaaa atctgtcggc
     8641 atcaacatga gtctaaaagc tcaaggagtc acacaagaaa cactagatac aaccgtagac
     8701 cgtatggctg aattagctta cgaagaccaa tgtacgacag ctaatccgaa agaaccattg
     8761 atctctgaat tgaaacagat catcattgat gcttacaacg gataagcaaa agaaagcgta
     8821 gaaaaaagat aagaaaatag atgaaaaaga acttggaaaa cgttgtttct ccaagttctt
     8881 tttttaattt ccaagtaact gaaagttact tttgttattt aacatttagg tcaattttag
     8941 acagtttttg ttcaaaaagc gatatttata gtggacggta ttactgctat attaaggata
     9001 taaaatgaaa gcgtttaaaa aggtggcgta aagatgatta ttaaagaaga gatttttgta
     9061 cctaaagaat tagtgaaaga aaaaattgac ctgctcgttg aaaacctgac aacgatcaaa
     9121 gacgataatg gtgaattttt gttggacttt gatggactga aagtagatga caaaagctgg
     9181 acagtgtgga attggccaca aggtgtcggt ctatatggta tttataaaaa ttaccagatg
     9241 acaaaaaatc ctcgcgctta tcaagtggtc aatgaatggt ttgaggatcg tatggaagaa
     9301 ggcgctccgc ccaaaaacgt caatacaatg gcaccgctat tgactatggc ttacttgtat
     9361 gaagacacga aagattcacg ctatttgcct tatttagaac aatgggcaga atgggtcatg
     9421 aatgacatgc ctcggacaaa tgaagacggg ttacagcatg ccacatatgg accggaaaat
     9481 aagaatcagt tgtgggacga tacattgatg atgacagtgc ttcctttggc aaaaatcggg
     9541 aaactgttga atcgcccaga atatttagaa gaagctcgtt accagtttat gatccatatc
     9601 aaatacttga tggataaacg aacaggattg tggtatcacg gctggacgtt tgaaggaaat
     9661 cataactatg ccgaagcatt ttgggctcgt ggaaactgct ggttgacgat tgctattcca
     9721 gagatcattg aaatcttaga attatcgaaa gaagatgcat tgcgcaaatt attgatcgaa
     9781 acacttgaag cacaagtgcg tgcattaaaa acttatcagt ctgaaagcgg tttatggcat
     9841 acgttgttgg atgatccttc ttcttacgta gaatcttctg caactgcagg atttgcttac
     9901 ggtattttga aagcggtcca taaacgttat ttaccacaag aatataaaga agtcgcttat
     9961 cgtgctatcc aaggattgct tgaacaaatc gatgaaaaag gagaagttca aaacgtttca
    10021 atcgggacag gaatggggga cagtttagat ttttatcgga atatcggaat cacagcaatg
    10081 ccttatggac agtcgttaac ggtgctttgt ttgacagaat tgctcgtctc ttattgttaa
    10141 aagaaaggaa acccatatga aaaaaacatc actgctgttt gcagcaagtt cgcttagcct
    10201 aggtctgcta ggtctaagcg gctgcggaaa taattctagt gtggcaactg tcgcagatgc
    10261 agatgtaaat gagatagtta ccttgcgctt tgcttatgca agcaacagcc agccagtaat
    10321 tgatgcaatg aatgaatttg ggcgtttagt aaaagaaaaa acagatggtt ccgtacagat
    10381 ccagtatttc ccagatggac aactgggtgg agaacgtgaa ctgatcgaat tgacacagtc
    10441 aggagcagta gatttcacaa aagtaagtgc ctcagcgttg gaaagtttct ctaaagatta
    10501 ttcgattttt tcagttcctt atctattcaa tgatgaagaa catttcttta aggtgatgga
    10561 taatgaagaa ataatggagc caatctacca atcgaccaaa aatttaggat ttaccggatt
    10621 gacctattat gattctggtc agcgcagctt ttatatggta gacggtccga tccatacgcc
    10681 ggaagatttg gagggaaaga agatccgtgt gatgcaaagc gaaaccgcta tcaaaatggt
    10741 agagctttta ggcggttcgc ccgtacctat gggaagtgat gaagtgtaca cgtctcttca
    10801 atccaatttg atcaacggat cagaaaacaa tgaatttgtc ttgtatacag ctggacatgg
    10861 tggtgtggct aaatactatt cctatgatga gcatacacgt gtgccagata tcatcatcat
    10921 gaatgatgcc atcaaagaac agctaactga tgagcaggaa aaagccattg aagaagcagc
    10981 gaaagaatca acggtttttg aaattgaagc ttttgcaaaa gcaattgaag aagaaaaagc
    11041 tttagcacaa gaagaacatg gagtccaatt caatgatgta gataatacac cgtttcgaga
    11101 ggcagttgcc ccacttcatg atatattcaa aaacgatcct acctacaaag acctttatca
    11161 aaagatccaa gagcaaggag cgtagctgtg atgaaaatga ttttaaacaa ggtattagag
    11221 atcctgggag ctgttttgct tgttgggatg gtcgctgttg ttttatggca agtattttcc
    11281 agaacggttt taggaaatcc aaatacggtc acggaagagc ttgttcgatt cggtcttgtc
    11341 tggtttgcca tgttgtcttc cgcgtatgtt gtgggacaaa aagcacattt agccgtaacg
    11401 gttttaagtg aaaaattaac tggcaaaaaa agtaaaattt tagaagttgt tgttcaaagt
    11461 ttatttctgg tatttgctgc gatgatcatg gtgtatggcg gatggaatgc tgtcacattg
    11521 acaatggggc agatctcgcc ttctttaagt attcctatgg gatatgttta tctgtcagta
    11581 cctgtatcgg gggtactcat cattatctat agcctgatca atctaatcga tacattaagc
    11641 aacaagccag caattcaaga aaaaatataa aaatggagga ataaaatggc aatagaagcc
    11701 ggattagtgt tattttttgt atttgttgtg ttgcttgtat tagggatgcc gattgctata
    11761 agtattgcat tctcatcgat gatgacttta ttgttagtta taccgtttga tgtttctgct
    11821 tttagttcag ctcaaaaaat ggtgggaagt atcaatagtt tttcgctgat cgctattccg
    11881 tttttcgttc tctcgggcat tatcatgaat aatggaggga tagctaagaa actagtggat
    11941 tttgcgatgt tgttcgtcgg gcgcgtgccg ggggctttgg ctcatacgaa tgtgttaggg
    12001 aatgctttat ttggttccat ctctagctcg gccattgccg cttctaccgc gattggcgga
    12061 gtgttgatcc ctcagcaagt ggaagaagga tatgaccgga agtttgcgac agcggtcaat
    12121 atcgcgtcag ctccgacagg tatggtcatt cctccaagta ctgcttttat catgtattca
    12181 cttgttgctg gtggtgcttc gatctctgct ttgtttatgg gaggttatct cgtaggcgct
    12241 ttgtgggcgc taggaatcat gctagtagca ttcatcgttg ctaaaaagaa taaataccct
    12301 gttgtcgaaa aaggacagat ggctcatgct ggaaaaataa taaaagaggc gattcctagc
    12361 cttctattga ttgtcatcat tatcggtggt atcttgacgg ggatatttac agcagtagaa
    12421 gcttcagcga tagctgtcat ttactccctg ttgattgcta tgttttacta taaaacggta
    12481 aaactaaaag atatacctaa tatgttgttt caatcagtag caatgtcagg gacgatcatg
    12541 ttcttattgg ctacttcttc catgatgtct ttcgccatgg cgtttaccgg tattcctcag
    12601 gcaattagtt cgttgattat gggcgtaacg gataataaat ttattattct gttattagtc
    12661 aatcttgtgt tattactggt gggtatgttt atggatgtgg cgcctgctat cttgattttt
    12721 acaccaatat ttttaccaat cgtcacaagt gtaggggttg atcctgtaca ttacgggttg
    12781 ttttcaatca tgaatctgtg tgtaggctcc atcacgccgc cagtaggtac aggactatat
    12841 gtcggtgcaa gtgtaggagg cgtaaaagca gaggcaatgc tgaaaccgct tcttcctttt
    12901 tatggggtta tcttagtcgt cttgtttttg attacttact tcccgcaaat cgtcatgtgg
    12961 ctacccaata tgctgagtta ggagaatagt tatgttgaac attacaatta gaggacatga
    13021 tctttccgaa gtccaaacga tagaagatct tgcagaaaaa acaaaagaac aagggattca
    13081 tacactgcag ctcgccttag gtctttcgtt tcctgaaaca ccttctggcg caaatgagat
    13141 caattctggg atgggaaatt atgtcaaacg agttttagaa aagcaagaag tgaccgtagg
    13201 aattttaagt tgctatatca atatgattca tccagattta acgatacgac aagagttgct
    13261 gacaaagttc gagcagtatc ttcgctatgc ttcttccttt ggtgcgtcga tggttgcttc
    13321 ggaaactgga tgtgttttgc cggaaatcca atatacggaa gaaaatttca cagatgaagc
    13381 atttgctgaa gctgtgtccg ttatccgtcg cttggtaaaa gctggagaaa aataccaaat
    13441 gatggtgggg atagaaccag gtttgaatca tccggtgtat tctttagcaa gggtagagca
    13501 gctgatccaa gcagtagatt cggactatct aggaatcatt ttagatccga ccaatttgat
    13561 cacaagtagt gattatcaag aacaagtcca attggtagaa gaagcttttg aacgttttgg
    13621 tgaaaagata tgtgcggttc atttgaaaga ttttcgtgtc gaacaggaaa aaatcgtgcc
    13681 ggtaaatttg ggagacggtg tgatcgagta cacaaaaatc aaagaaatca tcatgaagaa
    13741 tcgtccgtac ctgtatgtgg ttcttgaaga aacaaaagat gatgggattc gttatggaag
    13801 aagtcttctt gaataatgta aagaagacgt tggttaacta atatttagaa tggagggggc
    13861 ggggctagaa gatgccacgt ctcttctttt ttataagagt atataaaagc agctcttttt
    13921 gattacaaaa aacgtggtat aataaaattg tgcataagtg aacaaaagga ggtgcggcac
    13981 atgctccaaa agaaaatcag cggtgaacaa gtcaatacga tggtttctga tcagtatgaa
    14041 atctatcatg tcaaagatgt cgtcagccaa aataaaacga tctatcatca tcatgatttc
    14101 tatgagatcc atgctacatt aaagggagaa gcgacttttt atttgaacgg acgacaattt
    14161 acgatcaaag caggaagtgt gctgctcatc cattccaatg atttgcatcg tatcgtccgc
    14221 caatcttcag atgtattcga gcgtgtctat atctttgtca ccccttcttt tctagaaagt
    14281 cgttccacgc catggtctaa tctatcggct tgttttcaac caatgggaga gaagaggagt
    14341 cgtgtattgc aaatagaaca ggaagtattg aagcaaaaat tatcatttat cgaccatcct
    14401 cctgataaaa aaatttacgg tgaagacata aaatatgaac aagctctggt agaatacttg
    14461 atttttctca atcaagttgt acaaaaagaa gagagtgcgc aagaacagaa tgctgtagtt
    14521 cctaatgagc gtgtggaaca aatgttacaa tatatctcaa aaaatttatc tcatccgctt
    14581 tctttagagg aaatggaaaa gcagtttttt gtcagcaaat accatatcac acgagaattt
    14641 aaaaagtaca ctggatttac gtttcatcag tatgtaatga agaaaaagct gatctatgcc
    14701 aagcacttgt tgcgagaata ccgcagctct agtgctgtat atagtaaaag tggtttttct
    14761 tcttatccgc attttctgaa agcattcaag agagagttcg gcataacgcc taaagaattt
    14821 ttgaaacgtg atacacagaa acagttggtt cattatgaac attttgaaga tgaacaatga
    14881 gaatgatcac taaaaaataa ccgcagtagc tgctgttgtt tacatagaag cagaaactgc
    14941 ggttatttta tttttatcta tatatttcaa aatattttga aaaaatgacg tacatattat
    15001 atgaatcagc tgaatttacg aaagtctctc ggcgatagtc ctgtttttgc tttgaacagg
    15061 cggctaaagt aagcaaaatt ctcaatccct atttcttcgg aaatcattcg aaccgtaaat
    15121 tctgtatacc gaagaaggtc tttagcgtaa gaaagttttt tgctgatcaa ataatcgatt
    15181 ggtggagaac cgataaattt ggaaaaatct ttgctcagct gatatttatt caataagaat
    15241 tgttgttcta attgatcaag tgtaatcgtt tctttgaaat gttcgtctaa gtattgcttc
    15301 agtttgtaaa cgtaggcggg aatatcctct tcttcgaaat ctagctgata cttttgcaaa
    15361 atcagttcat tcagcaactc gtggatagct acagaggact ggaaatcggt acgggcattc
    15421 gtgccttgtt gcatgtggat caattctgtg atcaaatggt ggatcttgtt ttctgatgga
    15481 tcccctgttg aatggaaggt gttatggccg tcttttgtga actcctgata aaatgattgg
    15541 acgttctgac cattcaaatg gatccaatcc atttcccatg gttcttcgct gatcgtttga
    15601 taacgctgat attcttggca gtcaataaaa aataagtctc cagcttttag ctgttgctga
    15661 ttatcattat atgtaagcga acctttgcca gacaaagtaa actttatcaa gtaagaaggt
    15721 aaatgtgctc gttcagtata gtaagggatt ggtgctttga agtaaccgat ttcttggata
    15781 taaaaaaata aattcctgct tctttgtgta ggcgtcaaga tcactctttt tgagtcttcc
    15841 gaccatgagt ggttggcttt ttcccagtaa tccatgtaaa cactcccaac ttgtcaagat
    15901 aatgcaatta tataccaaaa tagtgtgaag caaaatataa gattctgtat tatgatagca
    15961 ttgttaataa atgataacgc tttattaata aagtgctaat caacaataaa gtaaaagagg
    16021 tggagaaatg aatccaacat ttgttgccat cgatatcggt gcatcaagcg gacgactaat
    16081 gaaaagtacg agggatgcaa aaggttcttt gatcttggaa gaagtacacc ggttcaaaaa
    16141 cggctttcgg aacaaagacg gtcacgatcg ctggaagatc gattatctta tcaaagagat
    16201 tttgattgga tttgaaaaat taaagcagac agggattgat cgcctttttg cggggatcga
    16261 tacatgggca gtcgattact gtctgattga tgaacaaggg gatcggataa atgatccgat
    16321 tgcttatcgg gacaagcgta ccaatggagc agtagaacag ttttctgaaa tctattctct
    16381 agataagttg tatgagcaga cagggattca gatccagcct ttcaatacct tgttccaatt
    16441 gtttgctgaa gaaaaagaaa atttggcaaa agcacataaa ttgttactga tacctgatta
    16501 tttagggtat gtctttactg gtaacatggt gacggagaaa actaatgcat ctactatgca
    16561 gctgctgaat gcagggacaa aagaatggga aatagaactt cttgaaaaaa tcggtgtctc
    16621 gaaggaatta tttccaccat tgacagagcc gggaacgata ctaggagatc tgcaaaaaga
    16681 acaattttca aaatatgatt tgccagatgt gacctttatc acagtagcaa gtcatgatac
    16741 ggcgtcagct gtattaggaa cgccaggtca aggagaacgt tggggttata tcagcagtgg
    16801 gacatggtcg cttttaggga ttgaaacaaa gatcgccaat gtttctcgca atgctttttc
    16861 tgaaaattat acgaatgaat ggggtgccca taacacggtg cgttttttga aaaacatcat
    16921 ggggatgtgg ttgatccagg aagttgcccg aatgcaagag tacgagtaca gttatgcgga
    16981 attggcagag cttgctgcaa aagaaaaacc gctgcagcaa gtgatggaaa tcaatgaccc
    17041 tcgatttttg aatcccccaa atatgataga agagattcag caatactgtt ttgaaacaga
    17101 gcagccagtc cctgtctcat cgggagctat cgctcgttgt gtgtatgata atcttgctct
    17161 ttgttacgca caagagctga tcaaagtaga acacttaact ggaacgaaat tggaaaagct
    17221 gcacatcgta gggggcggat cgaataatcg tctactgaat caattgacag cagattatgc
    17281 cggaatcatt gtagaagcag gacctagtga agccacagca atcgggaatg ttgccatgca
    17341 aatgctcagt acaggtcagt tttcgaatat agaacaagca agaaatgtaa tcaaacagtc
    17401 gtttccatgt gaaacttttt acccagatga aaataagcaa aacacgatgg aatggtacgt
    17461 gaataaaatc aaaggagtaa tcgtatgaac acgattgaaa gaaattacga acaagcaaaa
    17521 gaaaaatatg caactatcgg tgtagataca gatgctgtac tagaaaagat acaggacatc
    17581 aaaatttcta tgcattgctg gcaaggagat gatgtcaaag gtttcttgac accggatggc
    17641 gaattgaccg gtggaatcat ggcgacaggg aattttccag gagccgcacg aacacctgaa
    17701 gagcttagac aagatctgga gaaggcttat tcgttgatac cgggcaaaca caaattgaac
    17761 cttcatgcta tctatttgga tacagaagaa tctgtcgatc taaatgaaat tgagccgaaa
    17821 cattttgaaa aatgggtaga gtgggcaaaa aaagaagaaa tcggtcttga cttcaatccg
    17881 actttctttt cgcatccaat gatgaaagac ggctttacat tggctcatcc agataaagaa
    17941 gttcgtgaat actggatcga acacgggaaa agaagccgca aaatcgcgga gtactttggg
    18001 aaagaaactg ggcaaacaag tatcaataac ttttgggtac ctgatgggat gaaagataat
    18061 ccgattgatc gttttacccc acgggaacgt ttaatggaat cactcgatga aatttttaca
    18121 gaagagttag atgaacggta tgtacaagat gcagtagaaa gcaaactatt tggtttaggc
    18181 gctgaagctt atacagtcgg ttcccatgaa ttttatatgg gttacgggtt gactcgtgac
    18241 aaacttgttt gtctagatgc tggacatttt catccaacag aagtgatttc caataaatta
    18301 tcttcattag ctttattcag caaaggaatc atgttgcatg tttcccgtcc agtgcgttgg
    18361 gattcagacc atgtggtttt gatggatgat gaattgcagg aaatcgctaa agaattagtc
    18421 cgtaacgaat tgttggaaaa aacaaatatc ggtctggatt tctttgatgc aacgatcaac
    18481 cgtatcgctg cttgggtcat cggtacgaga aatacacaaa aagcactgct gaaagctatg
    18541 ctggaaccag ttgagcgatt gaaagaaatg gagctggctt ttgactttac ttcaagaatg
    18601 gcttatacgg aagaattgaa agatttcccg tatgccgatg tatggaatta tttctgttac
    18661 aaaaatcaag ttccagttgg tttggattgg ctggaagaag tccaggaata tcaaaaagac
    18721 gtgttggaat taagaaaata ggagtgtggc tatattgaaa aaaatagata ttttacaagc
    18781 gccttatgtg aaagaaatga tcgaaacgac gtcgaatctt tatcgcttgg gatgggatga
    18841 aagaaatggc gggaatattt cttatttact aaaagaagaa gagatcacac cgttcttgga
    18901 tcctgaaaaa gtgatccgcc gcatctcgat gatttttgat gccagccgtt tagcaggatg
    18961 ctattttatt gtaactggtt caggaagata ttttaaaaat gtagcgagcg aacctgccga
    19021 gaatcttgga atcgttcgag ttgctgaaga tggcaaaaca ctggaacttt tgtgggggct
    19081 ggaaaacgaa tgccttccta caagcgagtt gccaagtcat ttcatgagtc atatcgcccg
    19141 tttagaagta gacccagata atcggatcgt tatgcattgc catgctagtc atctattagc
    19201 gatgagtttt acgcatgaat tagacgaacg ttcctttagt cgtacgctat ggcaaatgtg
    19261 tacggaatgc ttagttgttt ttccagaagg aatttccatc attccgtgga tggttccggg
    19321 aacaaatgag attggggaag caacagctga aaaaatgaaa gaaactcgat tggttttatg
    19381 gccacaacat ggaatctacg ggtcaggaaa agacatggat gaagtctttg gtttgatcga
    19441 gacagcagaa aaggcagcag aagtctatac gtacgtcaaa gcgcaaggac caatcttgca
    19501 aacaatcacg gacgaaaacc tgtggcattt agcagatgcg tttggtgtca ctccaaaagc
    19561 aggttatttg gaggaagttc atacgaaagc aggtgtctga catggtgaaa aaagcttttt
    19621 gcatgaaagt ttacccagaa aaacaagaag aatacaaaaa aagacatgat gaactttggc
    19681 cagaaatgcg tacagcactt cgtgaacacg gggtcatcga ctattcgatc tatcttgatc
    19741 cgagtacaag tttgttattt ggttacttag tgatcgaaga tgaaaagtta tgggaaaaaa
    19801 tggcaaatac atctatcaat caaaaatggt ggaagtacat ggaagatatc atggagacaa
    19861 atccagatgc ctctccagtc agttgggaat tgatgccagt ctttgaactg tagcaacaag
    19921 caactgggca accggttgct tggggttctt tcgtttttat tgtgaaaaaa aatacaaatt
    19981 aggaggaata gaaaatgagt aatcgaatga ttttaaatga aacatcgtat tttggaaaag
    20041 gagcgattga gtcgatcgtc cctgaatttc agcagcgagg attcggcaaa gcagctgtca
    20101 ttactgacaa aggattgatc gagcacggta tagcaacaaa agtaacagaa cttctagata
    20161 aagcagcaat cgcttatgct ttatacgacg ggatcgtacc taatccaacg atccaaaatg
    20221 taaaagatgg agtggctttt gttaaagagg cagaggcaga ctgtttgatc gcaatcggtg
    20281 gaggttcgcc aatcgatacg gcaaaagcca ttgggattat tttgacgaat ccagagtttt
    20341 cagacgtcat tagtttagaa ggtgttgctg atacgaaaaa tccatgttta cctatattag
    20401 ctataccaac gacttctgga acagcagcag aagtaacgat caactacgtc atcacagatg
    20461 aagtaaatca ccgaaaattt gtttgtgttg atcctcatga tatcccaatc gtcgcgttca
    20521 tcgacagcga tatgatgatg ggaatgccga aaaaattggc tgcatcaaca ggtatggatg
    20581 ctatgacgca tgctattgaa gggtttatca caaaaggcgc ttgggaaatg actgatatgc
    20641 tgcatttaaa agcaatcgaa atcatcggcc attctttgga agtttctgta gatggcgatc
    20701 aaaatgggcg agaaaaaatg gcattaggac agtatattgc gggaatgggc ttctcaaatg
    20761 tcggtttagg actggtacac gggatggctc acccgttaag tgcatggtac aacattcctc
    20821 atggcgtagc gtgtgcagca cttttgccaa ctgtcatgaa atataacaaa gaatatactg
    20881 gagaaaagta ccgtgagatc gctcttgttc tagggattaa aggagcagct gaaatgtctt
    20941 tagaagatgt aagagaagcg gcttgtggtg agatcgatcg gttgagcaaa gcggttggaa
    21001 tcccagaaac catttctgaa ttaggtgtaa aagaagcaga tattccagca attgcagaag
    21061 atgctttgcg agatgtatgc acaccaggaa atccaagaga aacgacagta gaagaaatca
    21121 ttgctttata tcaaagtttg atgtaaaaac gaagcggatc ttcaacatta aattgcctgt
    21181 aaagagaaat ggtagtttat atctggatat ctcttttaaa ttgatggtat ttccgctata
    21241 atttttctta taaagaaata ggagaatatt atatggaaaa taaaaagcct tatggaactg
    21301 tattgatcaa agcctctaaa atactagact atttagcgga aaaccaagat gtctctttgc
    21361 agacgatcgc aaagggtgtg ggaatgacct cttctacagt cttgaaaata ctagatactt
    21421 tgttgatgat cggctacgta aataaaaatt cagagaaaaa ctatcgttta ggtgcaaagc
    21481 ttattcgcta cgcgaataaa aacattgaac aaatcgattt ggtagagttg actttaccgt
    21541 ttttagaaca gctgcagcaa aagatcgatg agactatcca cttaggggta ttggacaaca
    21601 atgagatctt gtacgtgaac aaactagatc caaaacatca aacgatccgc atgtcttcaa
    21661 aaatcggaat cacccgacca ttatacaatt ctgcgatggg caaagccgta ttagcagaat
    21721 tcagtgaaga gcagtacact gattatcttg aaaagcatcc gttgatccct tacacagaat
    21781 atacgatcac caatgcatta cggttgaaaa aggaaatcca aacggtaaaa gaaacccaca
    21841 tcgcatttga cgatgaagaa atcgaacgtg atattttttg tataggagcc tcaatcgtga
    21901 aaaacgaaca aatcattggt gcatttagtg taagtatgcc gaaatatcgt ttaacagatg
    21961 agacaaaaga acaaataatc agtgccctca agcaaacaaa aagcgaaatc gagcaaagaa
    22021 ttcaaaaata atgaaaaaag cgtttgcaat ttttcttttc tgccgtataa tatgggtata
    22081 gatttccaag ttataaaata aaatttctaa ataggaaata ggtggagaag atgaaaaaaa
    22141 ttgatatttt atctcgattg aaaaacgccg gagtgattgc ggtggtacgc ggaaaaagca
    22201 aagaagaagc tttgaatgct tgccacgcaa tcatcaaagg tggtctaact ggtattgagt
    22261 tgacttttac agtccctcaa gcagatcaag taatcaaaga acttttgtca ttctacaaag
    22321 accaaccaga aatagtgatt ggcgcaggca cagtattaga cgctgtcaca gctcgcttgg
    22381 ctatcttagc tggcgcagag tatattgtta gcccttcctt tgatcaagaa acggcagaga
    22441 tgtgcaatct gtatcaaatt ccttacttac caggatgtat gactattacc gagatcaaaa
    22501 cagcgctgaa aagcggggta gatatcgtca aactatttcc tggaagcgct tatggaccaa
    22561 gtatcatttc tgccttcaag gcgccgatgc ctcaagtcaa tatcatgcca actggcggtg
    22621 tgagtctgga caatatgaaa gagtggttcg atgctggtgt cgtaacagtc ggagtaggtg
    22681 ggaacctttt agcacccgca gctacaggag attttgacaa agtaacggaa gtcgcgcaac
    22741 agtatgcagc aaaaatgaaa gaaatcaaga ggtagctgct tatgggaaaa gtagtgacac
    22801 tcggagaaat catgttgcga ttgtccacag agcagggaac ccgtatcgat tcaagtgaac
    22861 gattcgctgc ccattatggc ggaggggaag caaacgtagc aatttcttta gctaattacg
    22921 gacatgaagc gatttttgct acaaaagtac ctgataacgc attgggaaaa gcagtcaaaa
    22981 agcacttgca atgttatgga gtagatacga aacaggtatt atctggtgga tcaagactag
    23041 gtacttatta tatggaaact ggtagtggcg aacgcgccgc ctcagtgatc tatgatcgtg
    23101 ccggatcaag ttttgctgaa atggatcatt tggaatggtc gctagaggag ttattccaag
    23161 gaatagatat atttcatgtt tcaggaatca ccccagcttt gtctaaaaaa tggcaaaaaa
    23221 tgacgaaaca ggtgatagaa gctgcaaaaa aagctggctg cctgatcagc ttcgatatca
    23281 actatcgtgg aaaattatgg acacagcaag aagccagcga agtaatccat cagcttttac
    23341 ctttagtaga tatctgctca gctggaaaaa tggatgctct ttatttgtta ggtatcgaga
    23401 aagcgccaga agcagaagaa caacctctaa tttattatta tcaaaaaatg caggaaaagt
    23461 tcccgaatat tcaggtgttt tattcgacca agcgtaccgt tcattcagca agtgaaaatg
    23521 aattgaaggg gacattgtgg atgaaccatg aatatgtgga atcccaagtc catagaatca
    23581 ccccaatcgt ggatcgagta ggtggcggag atgcttttgc aggtggcgtg ctccatggga
    23641 ttttatccaa tatgtctccg caagaaatca ttgattttgc tacggcagct tctgccttga
    23701 agcatacgat ccatggggac tgcaaccaat ttagtcaaga agaagtcgca caatttttag
    23761 catgcggctc tggaaaaatc attcgataga aggagtagaa gaaaatgcaa gaaatggaaa
    23821 cacgttatac acacagtcca gaagatatcc gtcattattc aacggaacaa ttgagaaaag
    23881 aatttttagt agaaaaggta tttgaaccag ggaaaatcag tttgacttat acgcacaacg
    23941 atcgaatgat ctttggtgga gtgacaccta ctgaaaaaga attagaaatc acattagaca
    24001 aagaactagg tgttgattac ttcttagagc gtcgtgaact aggtgtgatc aatatcggtg
    24061 gaccaggatt catcgagatc gatgggcaaa aagaagaaat gaaaaaacaa gacggatact
    24121 atatcggaaa agaaacacga catgttgtat tttcttctca agatgctgaa aacccagcta
    24181 aattctatat tagttctgtt ccagctcatc ataaatatcc aaatgtaaaa atcagtatcg
    24241 accaagtaaa accaatggag actggtgaag gcctgacact gaatgaacgt aaaatctacc
    24301 aatacatcca tccaaatgta tgcgaaagct gtcaattaca aatgggttat acgattttag
    24361 aaccaggaag cgcttggaat acgatgcctt gtcatacaca tgaacgtcgt atggaagctt
    24421 atgtctactt tgattatgcc aatgaagata cacgtgtgtt ccacatgatg ggcaaaccag
    24481 atgaaacaaa acatttagtt gtagacaatg aacaagccat tatttcgcca agctggtcga
    24541 tccattcagg tgtaggtaca agcaattact cattcatctg ggcaatgtgc ggagaaaata
    24601 tcacctatac agacatggat atggtgcaaa tggatcaatt aaaataagca taagggagag
    24661 aaaatgatgg aatttagtat ggatatgttt cgtttagatg gaaaagtagc attagtcacc
    24721 ggtgctgtct atggtattgg atttgagatt gcacgctctt tagctacagc aggagcaaaa
    24781 atcgtattta ataacttgaa tcaagaatca gttgatgaag gtatagcgca ttataaagaa
    24841 gcaggcatcg atgcaaaagg ttatgtctgc gatgtgaccg atgaagaagc ggttcaagcg
    24901 atggttcaac agatcaaaga agatgtaggt tcagttgata ttctagtcaa caatgcaggg
    24961 atcatcaaac ggacaccgat gatcgaaatg gatgcggcag acttccgcca agtaatcgac
    25021 gtggatttaa atgccccatt catcgtttca aaagcagtta ttccggatat gatcgaaaaa
    25081 ggcggcggta aaatcatcaa tatctgctcc atgatgagtg aattaggacg cgaaacggtc
    25141 agtgcttatg ctgcggcaaa aggcggatta aaaatgctga cgaaaaacat cgcttctgaa
    25201 tacggtcaat acaatatcca atgtaatgga attggaccag gttatattgc tacaccgcaa
    25261 actgctccat tacgcgaaac acaagaaaac ggtgaacgtc atccattcga tcaatttatc
    25321 gttggacgta cgccagcagc acgctggggc gagccaatcg atttggctgg accatctgtc
    25381 ttcttggctt ctagcgcatc tgatttcgtt aacggccatg tcttgtatgt ggacggaggc
    25441 atacttgcct atatcggaaa acaaccttaa aagagcttta gtacactgtt tagtggagag
    25501 gttgtgaaat cagcggattg aacgaatacc gaaggacagc tgattaaaca tcatttattc
    25561 gaaaaaagag gctgggacag aagcatttaa ctccaagaaa taagaaggaa ttcacgaaaa
    25621 ttgcttttca aatttttgtg aatttcagct tatttccgaa ggagttgctt ttacttccgc
    25681 cgtttgtacg tgtttagagc gtgagacaaa agtgttcttt acttttgtcc cacgctcttt
    25741 tctgtgcgtc ttccatactt cactaagtcg atccctcttg cttcgcacca atccttcact
    25801 ggtccggaaa agatcagaga ttgttggtgt agggccgcgg tattcgttgc gccgaccata
    25861 gtataaagca gacgaagctc ttcttgccat tgcttcatca gtataatagt ttcttctacg
    25921 ccgtgattca tcagatgcgt cagtacggtt cctgaagtac ccacggcatt tgcgccgaga
    25981 caaagggctt taaatatgtc ataggcattg cggatacctc cggaggctag gatttccata
    26041 gaagtgtctg cttcatttgc ttcaagcaat gaagagactg tcgattgccc ccagtcagct
    26101 aaataactca gttcccgctt ggagcgacgg gcgttttcga tctgggtgaa gcttgttccg
    26161 cttcgaccgc tgatatcaac tgtatgaact cctaaagcag ctagatcatt gagcgtttct
    26221 cttgtcatgc caaaaccgac ttcttttacg atgaggggga cgtcaatggc tgtttgagtt
    26281 tcttgaataa gtactttcca attggtaaaa tcacggtctc cctcaggcat aaccaactct
    26341 tgaggtgcat tcaaatgaat ctgtaaggca tctgcgtgaa acaatcggat agcttctttg
    26401 gctctttcga cagaagtccc tgcaccgatg ttggcaatga ttttcccgtg aggatattct
    26461 tgtcgcataa tcgtataagt atcggctaaa gaagggactt tcaaggcagc gctgactgaa
    26521 ccagtggcaa tcatcaaatc tgcttctctt gcgacgattg caagatcttg gttgattttt
    26581 tttgtttttt cgcttccgcc agtcatcgca ttgatataaa atgggctgct tagtgtaaac
    26641 ccaactgcct gtgtacttag atcgacatca gaaactgcta tttgcggcaa agggttatgg
    26701 atgatccgta cgaagtcaaa ttcgtttttt tgtttatcat gaaaggcttt agctagtgaa
    26761 acatgttcgt cttttcgatt catcggtttt cctttctttg atcgctatag acatgtaacg
    26821 gcagtggagt gatttctgct ttttcccatg cactcattaa aggaagaatg ccagatttct
    26881 ggtcaacaat tacgattccg caatcgcccc cacctgcacc agaagatttt gcggctcctt
    26941 catactgttc agctaaatta cacaatttgt tcaaagcagg cgtttcgatg acgaccccag
    27001 tgattgcaga taaatcatgc agtaattgtc ggttttttcg aatcatctgt tggatcaacg
    27061 ttacattatt ttctttaaac cctttgatca tttcgttgac acattctgta ctatttttta
    27121 agaaaagctg ataagccacc attttatctt ctctcgaacg gtgaacttga tcgaccaaat
    27181 cagaagtaga ggcagggcta cccgtccaac caatcaataa acgtaaatct tcaggagcaa
    27241 tcaatggctc aatggataga cctggccaat ccagggcaag taactcactg atagaatgct
    27301 gagtttcttg ttcttggagc caaggatggt cgaaggttga gaaagcgatc cagccaccat
    27361 aacagctagc agcgatgtcg ccgcaggaac cattatcttg aactgctaaa ttggctagtg
    27421 ctgcaatctt gaaaatctcc aactgagata aattcaacgc gtaaaaaaca ttcaaggctt
    27481 tgaccgttgc aacggtcacg gcaccgctag aacccaatcc atatttccgg ccatttgaac
    27541 tgtctaactc acttgttact ttcagatcat aaaaggataa aagaatgttt ttttcttgtg
    27601 catacttttc agtcaagcga atagcagcaa ggatataatg aaaaggattt tcccgaatat
    27661 ctaaaactaa ttctccgttg cgtcttgtcc aacgtacagg catcccacta tattgtgcag
    27721 attggatact tccgactttt cgtgcagatt ctacagtgac tgtcacgaat tgatcgactg
    27781 cagcgataac tgctggatgg cctgtttcaa caactgcata ttctccggca atatagagtt
    27841 tgcctggtgc agatacttca atcataaaaa tctcccttta ttcaataatc gcaattcctg
    27901 gaccagcatg tgcagtaatt acttgttctt tgctaaataa tttggtaaat gtttcttgta
    27961 cctcagataa atggctgttt tccactaaaa ctttgacatt agggccagca tccatcgtaa
    28021 agtagcatgg aatgccttgc tttctcaatt gtcgcaccgc atccatcgct tttaagctgt
    28081 caggagacca gtaagtgaat ggaggctggg cagctaaagt cgttccatgc atttttagtc
    28141 cgtttctttc catcgtttct ccgagaagtt ggaaatcttt tgttttgatt gcttgtttca
    28201 attgatatag atccccttca acggaatcta accagccttg ataaaaactg gatgtttcga
    28261 ctgtccgacg catcccattt ctgctggaca cttctttttt ctggtcgttg atcaaaacga
    28321 aaaccattgc taaatcgtct tcgaaagaat cggaagggac tggcttagcg taagaactta
    28381 agtcgtcatg gcctttttcc cattcgacga aaccaccgaa aatacttcgg caagctgaac
    28441 cagacccgcg tcgagcaaat cttgaaagag agagatcatc taatccaagc ttaagagcag
    28501 tattgcaagc gcctgctaaa gcagctagcc cgctggcaga ggaggctaat ccagctgcgg
    28561 taggaacgaa attctgactg attactgaag cttttagtga gaggccggct tctttacgaa
    28621 aaaggtcaag aaactgactg actttttttg ttgctttttc gtcttgcaag gtgccatcta
    28681 gataaaattc atctaccata tagctatcag aaaagatgac ttctgtctct gtataaaatg
    28741 catccaatgt taacgaaagg ctgttgttca ttggaaggat gagttcttca tttttcttac
    28801 cccaatattt gattagagca atgttggtat atgcgcgtgc tttgccttta aacataggta
    28861 tgtactccta atccttgtat ccaagtttca gcagcacccg catcttcaag tgcttgactg
    28921 atttcttggg cttttgtttt tgtttgtgct aatgcaatca tacagccacc gcgtccaccg
    28981 ccagttaatt tggcacccaa tgccccggta tcttttgctg tttggatcaa tagattaaga
    29041 aaatcattgc tgattgtcag cttttccaga agtgattgtg attcatccat tgtctgtgcc
    29101 aacgtttctg gtgaattttc aatgattgct tgttttgctt gcttcgtcaa gtatcctaat
    29161 ttttggatca tttgtccagt ttcatgaggc tgggtttcaa agaggtgagc gacatctttg
    29221 acggcttctc ttgtttgtcc tttgattcct gtatcagcga caatcaaaaa agcatcgatg
    29281 ttcaaagaaa agtagtcgaa aggatgccct tttgtaaaat aaatcggctg caagctgcta
    29341 gtagcggctg catcgattcc actaggatta ccgtgggcga ttttttccga aagctggaca
    29401 ttttctaata gtatttcacg agacaaagga aatgctaagt aatcataaaa agcacgagtg
    29461 actgctgtgg cgactgcagc gcttgatccc attccacgtt cagcaggaat cgtgctttca
    29521 atggtcagtt gcaagttttt ttggatgtca tgctgttttt ttaagtgaat gaataatttt
    29581 ttgatatttt ttaatgcatg aggagcttcg gctaaatttc ctgaatagta ggaagaaacc
    29641 agttgatcgt ccattgcatc cagctcttca aggaatgcgg tgacttttgt tgcatagaaa
    29701 ggaaaggcaa tcgctggttc tccataaaca accgcgtgct cgcccatcaa tatgatcttt
    29761 ccgcttgatt ctccttggcc atagtttgcc ataatctaac tccttctcac gtaaaagtga
    29821 tttttaagca aaaaataaag cgcccaaaac gagttgcgct gcttcacgaa tttttttgtc
    29881 cactaagggt ctcaaaaaac attcctcctt tattttacta aaaccatctc agaagtaaaa
    29941 ctaagaatac gttttctaaa gaaaaaacac ttttttctta agaatttttt gacttttttt
    30001 cttctttgac tagaaaaaaa tacaattgac actactagat attgggggta tatttaaaaa
    30061 ggttggagtt aaacacaata tttagtgatg aagtgagctg gaggtaaatg agcgtgatcg
    30121 ttttagcagg tacaattggt gccggaaaat caagtttaac agaaatgatg gctgaacact
    30181 ttgatagtca ggcattttat gaatcgattg atgataatga agtcttgccc ttattttatg
    30241 caaaccctga acagtatgct tttttgctgc aaatttattt tttgaataaa cgttttgcaa
    30301 gcatcaaaca agcaatgaaa gatgacaata atgtattgga ccgttcgatt tatgaagatt
    30361 cactgctttt ccatctaaat gcagatctag gaagagcaac agaaacagaa gttcgtgtgt
    30421 atgatgaact gctggaaaac atgatggaag aacttcccta tgctgcccat aaaaaacatc
    30481 cggatttatt agttcatatt cgtgtatctt ttgatacgat gttggagcgt atcgaaaaac
    30541 gtggtcgttc gtatgaacaa ttgtcctttg atccaagtct atacgattat tacaaagaat
    30601 tgaacagacg ttacgatcaa tggtatgaag aatacaaaga aagtccaaaa atccaaatcg
    30661 atggagaccg ctataatttt gtggaagatc ctcaagcaaa agaagaagtc ttgaaaatga
    30721 tcgaagaaaa attagcagag attcgccaaa ccaaagtagc catttgattt acagttgctc
    30781 aaataaaggg taaaccttta tttgagcgac ttttttcttt atactggaaa caaatgtcag
    30841 gaggatagag tatgcgggaa aaacactatt ttaatcaaga ccgtaatttt tggatcaatg
    30901 tacagcaaaa cgatgtgcta gctgttaaaa acttaaaaga agaatatggc attagtgacg
    30961 agatgctgac ttattctcta gataaaaatg aacgggcgcg cgtagagtac gattcttttg
    31021 atgaagcgtt actgcttgta tcaaatgttc cgcaccagca aaaagtcgat aatcattatg
    31081 aaactagtcc tatcgctttt attttaaaag aagacggttt gtttacattt accacgccga
    31141 ataccgagta cgtgattcga ctaattcgat cgcttttgga acgaatgcca gacatgagtg
    31201 tatacagttt attgtttcgt acattgtttt tgatttctga ttcctttttt cctttaatcg
    31261 aggaagtgaa tagtgaacgt cagcggctta atctgaaatt aagagaaaaa acaacgaaca
    31321 agaatctgct gcaactttca gatttagaga tcggtttggt ttacttagtt acaggaacaa
    31381 aacaaaatgt agtactttta gaacaaatca aggcattggc tatttatcgc aagttgtcag
    31441 aaaaggaaaa agaagagttg gacgatgcgc tgatcgaagc acgacaagca gttgaaatga
    31501 cgaacttagc ttcgcagatt ttagaccagc tctctggcac ttataataat ttgctgaata
    31561 acaacttgaa tgacacgatg aaatttttga cggtctggtc gctgatcttg accgttccaa
    31621 ctattgtgac aggattcttc ggaatgaatc tccagttacc ctttacccat tccgttttcg
    31681 gatggggaat cgccttgatc atcagtttgg tcttatctat ttggatgctt attgcactgt
    31741 ggcggcggat tcgttgatct agtctttgat ctgcaaacca agggcttggg cgatcacaag
    31801 tgcttgctct tggttgacga ttagtcccgc caaagaatct tgagataaag cgattgctgt
    31861 gaagaaatta gtcgtaaagt ctaatccctt cagagaagtt cgaaaccagt tcgaaccggt
    31921 caactgattg tcagacaaaa aaaggttttt ccaagtgacc tcataaaatt cgctgtcttc
    31981 taattgacaa tgatcgaagg agacagcttt caagtttgta ctactaaagg aagccatcga
    32041 agcaatacaa tcagtgaaag tacagtctcg aagataactt tcggcaaaat tcgtacctgt
    32101 taatttacat tgatgaaaca cgacttggtg gaaactgcca ccaatccact ccagattgga
    32161 aaaatcacat ttttcaaaaa tgacattact gcattcaaaa tgacgtaaaa ctgttttttg
    32221 catcgtaagt ttttggatat gactctctct taataccata tttttggcat cgagatagct
    32281 ttggtcaccc ccgttgatca gaagaccaga gaagatctcc tcatcttcta aataaaactc
    32341 tccctttgta agaagaggaa gagaaggtgg aataggttcg atttttttca tgtgggttca
    32401 cctcgttttt ctttagtata gcaaagaagc gggaatcact gctagaaagt ctgctaatct
    32461 aatcattttc agaaaaggaa gacaaactgt atgaaaaaca ttgacaaaaa gattagtttt
    32521 tgctatacta tgatggttga gaaataaaag cagaagcacc cgcttctcgc cttagttgat
    32581 aatgtcactg ggctagatag ttttcactgg ttctattagg tgaagtacgc gcgggttctg
    32641 taagagaact cgttttttta ttgccgttta ttcggtaagc ttttctttct ctcataatat
    32701 ttggaggtga atgaccatag caaaggatat gatggttaac gacggcattc gtgcacgaga
    32761 gttacgattg atcggttcag atggtgagca attaggagtt aagacaaaag cagaagcatt
    32821 gaatattgca gaacaagcaa acttggatct tgtgttagtt gcccctggtg cgaaaccacc
    32881 agttgcgcga atcatggact acggtaaata ccgtttcgaa caacaaaaga aagaccgcga
    32941 agcgcgtaaa aaacaaaaag tgatcaatgt aaaagaagtt cgcttaagtc ctacgatcga
    33001 cttgaatgac ttcaatacaa aacttcgtaa tgcacgtaag ttcttggaaa agggcgataa
    33061 agtgaaagct tctatccgtt tcaaaggccg tgccattacc cataaagaaa ttggtcaaaa
    33121 agtcttgaat cgcttagctg aagaaactgc ggatattgca acagtggaac aaaaagcgaa
    33181 aatggacgga cgcagcatgt tcttgacgct ggcaccgaaa aacgacagta agtaatttga
    33241 atgactaact ggctgttgga cagccgatag tcggataacg aaagattttg aggaggaaat
    33301 atagtcatgc caaaacaaaa aacacaccgc ggatcagcaa aacgtttcaa acgtactggt
    33361 aaaggcggat tgaaacgctt ccgcgcgttt acaagtcacc gtttccacgg caaaacaaaa
    33421 aaacaacgcc gtcaattgcg taaagcaagc atggtttcta gtggcgactt caaacgtatt
    33481 cgccaacaac tagcaaaaat gaaataagaa gtacaaataa cagaatctga agatttattt
    33541 ttattaggag gaattataca tggcacgtgt taaaggtgga acagtaactc gtaaacgtcg
    33601 taaaagagtg ctaaaattag caaaaggtta ctacggttca aaacacactt tatttaaaac
    33661 agcaaaagaa caagtaatga attcatacaa ctacgcatat cgcgatcgtc gtcaaaagaa
    33721 acgcgacttc cgtaaattgt ggattgctcg tatcaacgca gcagctcgta tgaatggctt
    33781 gagctactca aaattaatgc acggtttgaa agttgctgaa atcgacatca accgtaaaat
    33841 gttagctgac ttggctgtta acgatgcagc agcatttact gcattggctg accaagcaaa
    33901 agaagctttg gctaaataag ctaaacaatt ataaagagga aagaagataa cgaaaagtta
    33961 tgttctttcc tcttttttta tttacaatcc tccatcaaat gaaacaggac aataacgtat
    34021 aagtctaaaa tagcataatt aaggtttttt aattgaaaac tgaacattta tggtcaccct
    34081 ttaatgaaag cgctaactac ataagttaga atgagtttga ctgatatatt agtttgctta
    34141 tcagaaaaac aaaatggacg gaggaataac atgagtgata ttattattgg tattttgtta
    34201 gttatctcat tctttttcat ggtctggtac tgtgtaaaag gctacaactt gatggtcggc
    34261 tttgccatca tggctactgt atggatggga ttagcgctag tcggaaacac gttttcacca
    34321 aacccggcga tggaagggca aggagtaatt gatgtgttga cgcatatcta tacgacgggg
    34381 ccagctgagt acgccaaatc gatcttggta aatgtcttct ttggtgcctt tttcgggcgt
    34441 gttctagtag atagcggaat cgcagctacc ctgattcgaa aggtagttga acttggaggg
    34501 gacaagccaa gaatcacgat gagcttacta tgtattgtaa ccgctgttat attcatgtcg
    34561 atgacaggaa tcggaccagt gatttctatt gcagttattg tgttgccaat cttgatgtca
    34621 ttaggtattt cagtaccggt tgcactgttc tcatttatgg gctcgattat ggctggaatc
    34681 tttgctaata tcgtcaattt caaacaatat caaacgattt atgctggttt caatccagcg
    34741 gctgaaagct atacttataa tgactatttc caaattggta tgattgggat gattgtaagc
    34801 ttagttgtgg tactaacggt cgctaatata tcaatgaaca aaaagaaacg ctatgcaatg
    34861 gcagcaaacg taccagctga aggtggcgac gcaccaatga tctcatggtt agccgtatta
    34921 ttaccagttt taggggtcgt tcttttagat cttccaatca tcttaggttt tattctagca
    34981 ggtatctggg cattgctgtt tactggaaaa ttgcgcggag gttataaaga aatctgtcgt
    35041 cagtttgcga aattatttac agatggcgca gtagatgttg caccaatggt tggtttcttg
    35101 atgaccttag cgatgttcaa taattcagct gcgtatgctt ctccttattt ttcagctatt
    35161 tttggagatt ggataccgca atcaccatta gtcttggcaa tcgtatttgc tatattgaca
    35221 ccactaggat ttttccgcgg tccaatgaat ctagtcggtt caggctcagc tattttagct
    35281 gtcgtattag ctgttaatcc aacgatgtcg ccagcctttt tgttcccgtt atttgcaatc
    35341 acaacgattg ctcctcagca tttagatatt acacaatctt gggttgcttg gggattaggt
    35401 tatacaaaag taacttctcg agaatatatg aagaaatcca tcccaactgg ttggatcatc
    35461 ggagcgatct tatgcctgat cacgttctta ttgtacggga acgcctagta aacaaaacgt
    35521 cgataaaaac gattagatga atggaggaaa agaaaatgaa acgttttgtg cgaatgggaa
    35581 ttgatgttgg cggtacacat acgaaagcag tcgcaatcga taatgcgacg cacgaaatca
    35641 tcggaaaatc ttcagtgaaa acaacccacg atgatgtccg tggagtagcc gcaggtgtcg
    35701 ttcagtcttt tcaaaattgt ttgcgggaaa ataatatcag tccagaagat gttgtgtttg
    35761 ttgcacattc taccacacaa gcgactaatg cactgattga aggagacgta gcaaaagtcg
    35821 gcgtaatcgg gatggcaaaa ggtggattag aaggtttttt agcaaaacga caaactagat
    35881 tgaacgatat cgatttaggg aataagaaaa aaatagagat tgtcaatgca ttcttacctg
    35941 tcaaacactt aaatgtagac cgtgtttcag aaacgatttc ttctttagaa agagaaagag
    36001 cggaggtctt ggtttcttct atggcatttg gagtagataa tggggaacca gaacgagttg
    36061 tttatgaagc agcatcggta aaatcgatcc ctacaacgat ggcttctgac atcacaaaat
    36121 tatatggatt gacaagaaga actcggacag cagcaatcaa tgcatctatt ttaccaaaaa
    36181 tgctagatac ggcaacctct acagaagatt ccgtacgaga agcaggggtc aatgtttctt
    36241 tgatgattat gcgcggagac ggcggagtaa tggaaatcaa tgaaatgaaa aaacgacctg
    36301 ttttaaccat gctttccggt ccagcagcat cagtcatggg ctctttgatg tacttgagag
    36361 cgtctaatgg tgtttatttt gaagtaggcg gaacaacaac caatatcggg gtcattaaaa
    36421 atggacgtcc agcaatcgat tattcaattg taggtggcca cccaacatat atctcttcat
    36481 tagatgttcg ggttctaggt gtggcaggcg gttcgatggt acgggctaat cagtcaggaa
    36541 tcatcgatgt cggtccacgt tctgcacata ttgccggtct agattatgca gtatttacgg
    36601 agacagaaaa aatcaaaggt cctaaggttg aatttttctc tcctaaagaa ggagaccctg
    36661 ctgattacgt caaggtagtg atggaagacg gagaagaagt gactattaca aatacatgtg
    36721 cagccaatgt ccttggatta gtgcaagaag aacatttttc ttatggaaat gtcccatctg
    36781 cacgaaaagc catccaagca ttagctgatt attgtcatac gacggttgaa gacatcgcag
    36841 aacagatcat ggaaaaatcc tatgctaaga ttgaaccggt gattttagaa ttggcagaca
    36901 agtatcactt ggagaaagat cagatttctc ttgtaggtgt agggggcggc gctgcctcat
    36961 tgattactta ctttagtaat aaaatgggtg tgaaatattc gattcctgaa aacgccgaag
    37021 tgatttcttc tattggtgta gcacttgcaa tggtccgaga tgttgtagaa cgtatcatcc
    37081 cttcgccaag taaagaagat atacgatcgt tgaaaaatga agcgatgaat aaagcgattg
    37141 aatcaggcgc tacaccagaa tcgatcgaag tccacgtaga aatcgatcca cagacttcaa
    37201 aagtaacggc tatcgctact ggttctacgg aagtgaaagc aaccgatcta accaaggaga
    37261 tcacaacaga agaagcacta gagcttgctg cagaggatat gcgattaaat aaaaatgaag
    37321 tttgcttatt ggaaaataca cctttctttt atgtatgcgg cgaacagaat cgttcaaaaa
    37381 atgctggaag tcttcggatc atcgatcaaa aaggatttat caaggtccaa cgtggacatg
    37441 cttcatgtat gaaaacaact gcagccaatt atatgacagc tgtcgaacaa ctttgggaag
    37501 atatggcagt ttatcaaact gaattgattg cccgaccaga attttatctc tgcttaggag
    37561 caagagtctc tgattttaca gcgacggatc tggaacaact acagcttttg atggatctgg
    37621 aagtatctac tatggaaccg gaggaagaag tgatcgtcgt tgccggaaat atcaaacaaa
    37681 cataagttag aagagttact aaacgaatta caacagatcc ccgaagaaat ttggggattc
    37741 taccagtttc ggcgagattt attttggaaa aagattcctt tgtccaagca gaaaattctt
    37801 atacaacaat caatcgattg tggtatcgaa acggcatgta gcatcaaaaa aaagtaccct
    37861 tttgccgatg taggagaaat ttgtgaacaa atggctgttc caatcgtttc ctgtgaatca
    37921 gagcaaataa acgaacgaat cacttttgca acttatgcag aagatgaagg gattcgattg
    37981 atgacggagc cgttagaaaa attaaaatgt tcaggactag cttcgatctc taaagaaaca
    38041 gcgcaagctt tgattattgg acatgaacta tttcaccaca tcgaagcttc tgttaaggga
    38101 atttatacgc aaagcgaaaa aattgtgctg tggcggttgc ctttttatac acatcaatca
    38161 aacattcgtg cattgagcga gatagcagcg atgagttttt caaaagagat gaatcaaagc
    38221 gatttttcgc cttatgtatt agaggcagtc ttactttggc catataatga aattcgtagc
    38281 caagggatct tagaagaaat aaaaaaaata gaaaaaagat gtacggagta tgatttagat
    38341 tacaaataaa gagactgtga caaaagtcgt gtcacagtcc tttttttccg aataaacgat
    38401 gttctcctgt caactcctcg gtcacaagtc aaaatattca acaaacatga gaagctgttt
    38461 tttgaaattg ttccttgtga ctcggagatg aacggcaggc tcacgacctc ttggaaaacg
    38521 gtgttcaaaa gcttgcatct gcggtaataa gtccagccaa gttaaaaaca taagaagcta
    38581 tttttacttg gctgttctta ttacttgatg cagggcagct ttttcacaac ctctcaataa
    38641 acggtgtgca atcagctgac cctcggtatt agctcaaaaa aaacggcaaa atatgaggaa
    38701 ctattttgcc gtttctttct ctaatactca ggtcaaaacg ctgattccaa aacctcttat
    38761 ttgatgggtc tgtcctgaat atcttcaaaa taatcggggt aattatgaat cacgtattct
    38821 tgctcctcga taatcatatg taaatgcatc gtgcaaagaa atccgacttc atcaaagtta
    38881 tgatcaatca ttgattgaag cattgtctga tgttcatcta atactcgacc ccagtctaat
    38941 tctgaaatcg tcaaacgtaa ccatctgaaa cggttcaagt gcgtactata actttctagc
    39001 caatcccaaa tttctcgttt tccagcaatt tcataacaag ttcggtgaaa atcagtatcc
    39061 aaatcaaaaa aagctttttt attttgagcg attactgcct gatcggtttt tccaactttt
    39121 cccgcgtata acgggctaat gaagcagatc ggatatcgat ttttgaaaca taagtgccgg
    39181 actgtggaat ggtttttaca agctcttgat tgcgcagttg gatcagtgct tctcgaatcg
    39241 gtgtacgccc gatagctagt tgttcttcta acactttatc ggagatttta cttccaggtg
    39301 ctaactcgga ataaatgatt tgtttacgta tagattcata agcttgctgt tgcaaattat
    39361 tgataaccat ttaaccttcc tttctatgca gatataatct attataacat aaatcgctta
    39421 caaatcgtgt gggcataaaa acacagtctg caaaaaaagc cctgataggc atgcctatta
    39481 gagcctcgaa aagaaaaata ttgaatcaat ctggtcgtac ctcttgtatc ggtttgacac
    39541 gaccgccgat tcttttagca aaagcttcgg attctttttt gtctttgaaa atgagcagat
    39601 tgtctaagtt tttttcccga gtgcgacagc cagttttatc gatgtaaccg tgcattactt
    39661 taacgacata catggggatc acctgctttt ttcttttcat tatacgaact actcgacaca
    39721 atacaagaaa aatgcttaga cggtctttat taagaattta catcatccaa agaagcgtac
    39781 gcttggaata actgatctaa ctccggattg actttgctca gcttcactaa tcgttgcgaa
    39841 tcagaaagta aaaaacagtg tttactactg ccagtagttt ttaatttttt gtcttcagtt
    39901 cccacaattt cgtagctaaa atccaaccgt gtccccgtat acttttggat agttggatgg
    39961 atgctcactt tttctccgta atggatcatt tctttatagc tgcaatttac ttccagaacg
    40021 gggatgatga tcccagattc ttcgattttt ttatagggaa accctagatg taccaataag
    40081 gctacccgag cctcttcaaa ccagcggata taattgctgt gatgaataat ccccatttga
    40141 tctgtttcat aataaaaagg ttctcgcaca taacctgtaa atttctccat gactcatgcc
    40201 tcgttttcca ttgatttttt acaaaaataa ttcatccatt tcggaagtgc ttcgctgatt
    40261 tgtgtcggca aaacaatata ttgttctttt gccagctggt ctccaatgaa actatgaaga
    40321 taaatagctg ctgcaatcgt ttggtcattt tgaggaaact gggctaaaaa tcctgtgatc
    40381 atcccagcta aagtgtcacc catgccgccc gttgccatag cagcagaacc taaaggattg
    40441 gtgtagaagt gctggtgacc ataaattttt gtctcatgac ttttcaaaac gagcacagca
    40501 ccgatttcct gttgcttctt tttgttttct ttatcccgtt gttcttgtat cggtagagaa
    40561 ctcaaccgtt gccactccat ttgatgaggt gtaagtacag tttgttcggg atagggtagc
    40621 aaaagatgat tagcagcaag taaacttaaa gcagagccat caatcaccag ccattgttct
    40681 tttgattggt tttctagtac ttgtttgaaa cgttccaaac tcttagaaga agtacccaat
    40741 ccgggaccaa tcaagagtac atctgcttgc tttattacgg aaagaaactg gtcagtatcc
    40801 gtccaaacta caatcattgc ttctggcaga tgactgtgaa gagcactccg atttttttca
    40861 tcagttacta cagtcgtgag acccgctccg ctgtgtacgg cagctaaagc actcataatg
    40921 attgctccgc catattgttc attgccgcca atcaaaacga tacgtccaaa tgttccttta
    40981 tgtgaaattt ttggacgagg tgtgatgact cttttcacta gttgttcgtt tatcagcatc
    41041 taaaaacctc cttttactca ttatagcgta tatttttttt agagaaaaac agataagaaa
    41101 aggaattgtc agattttttg aactattttt ttctgtaatt tgtggtatca tgaacacgaa
    41161 gacttaaata agtggaggat taactttatg acaattgatt ggcaaaaaga agtagaagca
    41221 cgtaaagaag acttgcttga agacttgaaa aatcttttac gtgtcaacag cgagcgcgat
    41281 gactcaaaag taacaccaga tgcaccattt ggacctggac ctcgcgacgc attgaaacat
    41341 atgttagctt atggcgaacg tgatggattt aaagtaaaaa atgtcgataa ctatgcaggg
    41401 catattgatc ttggcgaagg agacgaaacg ctagggatat ttggacacat ggatgtcgtt
    41461 cctgcaggag atggctggga cacagatcct tatgaaccag taatcaagga tggaaagatc
    41521 tttgcacgcg gatcaagcga tgacaaaggt ccaagtatgg cagcttacta tgcgatgaag
    41581 atcattaaag aacttgactt gaaactatca aaaaaagttc gcttcgtagt cggcagcgat
    41641 gaagaaagcg gctggggcga tatggcttat tatttcgaac atgaagaaga accagatttt
    41701 ggtttctcac cagatgctga attcccaatc atcaatggtg aaaaaggaaa tgtttcttta
    41761 gctttacgct tcaaaggcga caatgcagga gattatgtct tgaaatcttt tgtttccgga
    41821 cttcgcgaaa atatggtgcc aggaacagca actgcagcac ttcaagtacc aagtgcagat
    41881 gcagctatcg cgatggaaga agcattttac caattcatcg aagcaaatcc agtaagcgga
    41941 acgattgaag cggacaatac gtatgtaaaa atcgaattag ttggtaaagg cgcacatggt
    42001 gcaagcccac aatctggtat caatgcaggt tctttcttgg cattgttctt agataactat
    42061 gaattcctag gatctgctaa acaatttatc catgtagcag ctgcttatgt ccatgaagat
    42121 ttttatggag aaaaactagg agtcgcttat gaagatgaaa aaatgggcaa attgacaatg
    42181 aatgctggac tatttgcttt tgaagaaaat ggtacagagg aagcgaactt catcaatatg
    42241 aatttccgtt ttccaaaagg tgtaacagta gacggattgc aaagtgacat cgaacaaaca
    42301 gtggggcaag aaggcgcaac agttactcga ggtgctcgcg taatggaacc acattacgta
    42361 ccaatggatg atccattggt ggctacatta ttgcaagtct atgaagacca cactggagaa
    42421 aaaggctacg aacaaatcat cggtggcgga acttacggac gtttgttgaa acgtggcgtt
    42481 gcttatggag cgatgttccc aggatatact gatacaatgc atcaagcaaa cgaatttatg
    42541 agtcttgatg acttgttcag agcaacagca atctatgcag atgccatcta tcgtttggcg
    42601 aaataattaa ttaaaaagag gatcaagaat tgcaaattat ttttgcagtc ttgatccttt
    42661 ttttactttc tactgtggta ttcatgataa acatgatata gattcaattc atattctttc
    42721 ttagcgttcg tgacgactgt atccaaaatc aaccctgtta ctaatgaaag aagtgctaaa
    42781 gtcatcaatc cagtacttaa aatcgcagaa gggatgcgtg taataaagct tgtcagcata
    42841 tattcgcgaa tcacaggaat ccccgtgacc aatccaaata aaaagaagaa gatggtccaa
    42901 atcccaaaga aaagcaaagg cttataatct ttaaacattt taataatcat catgatcact
    42961 ttgaatccgt cagagaatgt attcaatttt gattcgctgc cttcaggacg atcacgataa
    43021 tcgattggga tttcaacgaa cttgaatttt ttatctaaag catggatcgt caattccgtt
    43081 tcgatttgaa aaccagaact cataatagga aaacttttga caaagatacg attgaatcct
    43141 cgatagccgg tcatgacatc aagaattttt gttttataca ttctagtaat tgtatttcta
    43201 acaaggttat ttccaaaatc gtggaaaggt ctcttattct catcaaagta ggttccattt
    43261 gataggcgat caccaatgac catatctgct tcaccagaac gtaatttctc gagcaaacca
    43321 tgtacagctt ctgcaggata agtatcatcg ccatctacca ttaaataata gtcggcatcg
    43381 atatcaaaga acatttggcg gatcacattt ccttttcctt gacgaggttc tttttttacg
    43441 attgctccac cttgaacggc caattcgtat gttcgatcgg tcgaattatt atcatagaca
    43501 taaatatctg cttctggtaa ttctcgttta aagtctgcaa tgactgttga aattgttgct
    43561 tcctcattgt aacaaggaat cagaacagca attttttctt gttgttccat ttttcactct
    43621 ccttaactat agaaaacaaa agctaaatta aaaatacctc ataatcaaag gaaatgctag
    43681 tttttcccgc taaatatcat ttatttaaaa agaaaatact ggaatatatg tttggaaagc
    43741 tctatctaaa aaaccaccca ctacaaaaga aggacatgat acctctcttt tgaatagtgg
    43801 gtgcgtattc gttctctcac ttttttgacg tattaatctg ttgcaccttt ttttcttgaa
    43861 atttctaata cggttcctgt atgagcatct gctaaaaatt cataataaac agtttcgcca
    43921 tcttctattc gagaaagacc tccccgataa gcactcgacc gaacggcgaa tttcctaata
    43981 ggttcctttt caaaagagat ccaagaacct tcgattgcac cttcttttag aaaagatgac
    44041 ttgatatttt caagtacttg gtctgctgac aatacttttt tgcgatgata ccaaatcgtt
    44101 gaagctaccc cgctcaataa tcctagaccg attccaactg ctaacccgcc tttaaaatag
    44161 cttagttcgc tttcttcata catgtggaca tacctccttc ttctcacttg ttactccttg
    44221 tgcttatttt accacactct catattttct ttgaaataaa taaccgctac cagaaaaaat
    44281 aagctataat aaatacgatc ggtctgcaga aaaaatcata ttttatccgc agatcaatat
    44341 aagtctgaga ggagtttagt ctgaaattta gacgaatagc atatggaaga aaaaacattt
    44401 caacgaatca aagagttaac agaattacaa ggaacaagcg gttttgaaca agatgttcgc
    44461 gcttatatgg aaagtcatat ggaaccgctg gtagatgagt tacagttaga tggtttgggc
    44521 ggcatttttg gtctgcgcca tcatgaagaa gcggatgcac cccgtgtaat ggtcgcagca
    44581 catatggatg aagtcggatt catgctgaca caaatccaag aaaacgggct ttttaaagtc
    44641 gtacctctag gcggctggaa tccttacgtt gtttctgctc agcgttttac acttaaaacc
    44701 tctactggta agaattatcc atgtatttct tcttccgttc ccccacattt attgcgagga
    44761 acaagcggac aaaaatcagt agaagtaacc gatattttgt tcgatgctgg gtttgaatca
    44821 agagaagagg caatgagtta cggtgtcctt ccaggagaca caatcgttcc ttacgctgaa
    44881 acgatcaaaa cagccaacgg aaagaatatt atcagtaaat catgggacaa ccgctatggc
    44941 tgtacaatgg tattagaagc tttagaagcg ttgcaaaatg aaacattagg tcatacattg
    45001 attgcaggcg cgaatgtcca ggaagaagta ggcttgcgtg gttctaaagc ttctgtcaat
    45061 aaattcaagc cagatctgtt ctttgcagta gactgctctg cagcagatga tacagtgacg
    45121 aaaaatggca cattcggaca tttaggagaa ggtacattga tgcgtatcca agatccaggt
    45181 ttgatcatgc ttcctcgttt gcgcgagtac ttgctggata tcgctgaaac aaacaatatc
    45241 ccttatcaat actttgtttc aaaaggcggt acagatgcag gtgctgctca tacacaaaac
    45301 gaaggaatcc caagtacagt gattggcgta gtgggacgtt atatccatac gcatcaaacg
    45361 atgttcagta ttcgcgattt tgaagctgca cgagaaatgt tgattcaaac actgaaaggt
    45421 ttggataaat caacagtgaa tacgatcgta tacggaaaat aatgcgatag tgaaactata
    45481 aaatctggca aaagattgct ttttgccaga ttttttttat aaaaagagga tcaatgtttg
    45541 ttagttcgaa agaaaggtgt ataatttaat tgaaaaatac ataaacagaa agtagaggac
    45601 aaagaatgat tatcccaaat agtttagaag aattagcagg ctacgtagaa actggaaaga
    45661 gtgtattttt ctttactgcc ggctggtgcg gagactgccg ttttatcaaa ccgcaaatgc
    45721 ctgaaattga aaatgacttt tctgattggc aatttattga agtagaccgt gacaagtaca
    45781 tagatgtagc cgctgaatgg aacatttttg gtatcccaag ttttgtcgtg atccaagacg
    45841 gaaaagaatt aggtcgtcta gtgaataaag atcgtaaaac aaaacaggaa atcgaatcgt
    45901 tcctagaaag tgtaacaaaa ggctgacatc tgttaggagg ggtcaagatg aatcaagaat
    45961 ataagaatat tttagtaggt atcgacggta gtgaacaagc acttgctgct ttcaaaaaag
    46021 cggtagaagt ggctcgccgt aataatggga aagtatatgt agcaaacgta atcgatcagc
    46081 aattttataa ctttatgggc tatgcaccta ttgatcaaaa tctagtcgat cagcaaactg
    46141 aaacagccaa ggaaatgatc gaagaatgta aagaatatgg gaaatctgtt gattacacaa
    46201 atatagaagg aattattgca tatggttctg ttcgtgaatc catggcagtc aaattgccaa
    46261 aaaaatatga gatcgatcta atcatggttg ggcagtcagg tctaaatgca gtcgaacgct
    46321 ttatgacagg aagtgtagcc agctacgtga tacgtcattc accttgtgat gtcttgatcg
    46381 tttctgacga agaagaacag ccaagtaatt aagcaagtgg aacttgtacg acctttttaa
    46441 tcaattaact aaaacagtaa agggactgtg acaaaagtct tgtcacagtc ccttgttacg
    46501 aataaatggt gttccagaag aggcttcttc ggaaataaag catgaaaaaa atttcatgca
    46561 gtgaatgcaa ttttttgtta agataaatct cagcaaagga taatggagga aagaacatga
    46621 tttttgctta taacaaagca cacgtcggag acaccttgat ggttattata gccgacgata
    46681 aaggaacaga aaacactgtt gaacgcaaat ggaatgttgc tcggatcaaa gatgaacaag
    46741 gtcaagttgt tgcttggaac tttttccata tctccgatca tctaacaatc gaagggaacg
    46801 gccaagtaag cttaacagat gaggaattag cgaaattgaa tcgattgatc aaagaagcag
    46861 gattcgaaga acagcttgaa gctgatcatg aaccgaagat cgttgtcggg tacgtaaaaa
    46921 catgcgtccc acatcctgat tctgaccatt tatcgattac tgagacagaa gtagacaatg
    46981 gtacagtatt gcaaatcgtt tgcggtgcac ccaatatcga agctggacaa aaagttgtcg
    47041 ttgcaaaacc aggagctatg atgccagatg gaatgatgat ctggccagga actttgcgag
    47101 gggtagatag ctatggaatg atctgttccg ctcgtgaatt gcatttgcca aatgctccag
    47161 caaaaaaagg aatcttagta ttgcctgagg atgccgtagt cggagaagca tttccaaaat
    47221 aaagaggttg tgacaagtct ttgtcacaac ctctttttta ttaattttca ctattttgat
    47281 tttgttttaa tgccgattga tcgatcgtca attcaacagt agttgttttt tctttcgagc
    47341 cttcatagta agtgattttg acagaatctc ccactttttt cttatacaaa gcagattgaa
    47401 gttctacacc agaagaaact tctttgtcat cgatcttagt aatgacgtcg tattgtttca
    47461 atccagcttt ttcagccggt gtagctgttt ggacatttgt cacgatgaca ccgttagtta
    47521 cagatgaagg aatcttcaag atttgttctt gttgctgagt agaaacggca gataagtcga
    47581 ccattgtgat acctagagct ggacgtgtca cttttccgtc tttttccagt tgattgatga
    47641 tattcactac atcgttactt ggaatagcaa atcccattcc ttctacgctt acattagaag
    47701 tagattcaga agtacttgcg atcttacttg agttgatacc gataacttgt ccttcgatat
    47761 taactaaagg accaccagaa tttccagggt tgattgctgc atctgtttgg atcgcattga
    47821 tattgactgt ttcgttcgat tcattcgtac ttgtcacttg tcggttcaag gaagaaatga
    47881 ttcctgaagt gacagaattt gcatattcag atcctagtgg ggaaccaatc gcaatcgcag
    47941 gctcaccaac cttcagagca cttgagtcac caaaagaggc aactgtttcg actttgtctg
    48001 aattgatctt caacaccgct aaatctgaat aagcatctgt tccaactaat tcagctttta
    48061 ccttcgtacc gtctttcatc aagacttcaa gaccttgctg gccatctact acgtgattat
    48121 tcgtgactac ataagcagta ttcccgtctt ttttgtagat cacgccgctt ccttcactat
    48181 aagcttccaa attactatca tctgagctgc tactttcttc ttgctgcccg aatagtccgc
    48241 caaaaccgct tgattggttt tgactttgta agttgataac agaaacgaca gcgtcttgaa
    48301 ctttatctac cgctttggtg atatcagaat ctacattgac tttgacattt tccacaactg
    48361 tttcaccggc agaattctga ttgccgcttg tagcagtaga actattgttg ccagtgccca
    48421 tcgctgcata aaaaatgcca gctgtcagta gtcctccaac gatccctcca acaagcccca
    48481 gacctaactt acgccagagg ctattatttt tacttttttt catctttggt gtcacatttt
    48541 ttctatccat gtgttcctcc tccaattaca ttcatttatc tactgttagt atagtcttat
    48601 ttgttgactt tagtctactt tgagactgtg aactttttat gaaaaacttt aggaaaaatc
    48661 attgttttca gatgaaaata tttgattttc tttttccaca gatactgtgt aaaactacgc
    48721 ggataggatt ggaaaaataa gggataaaac atatccacag cctgtgtata aagtggataa
    48781 attcttataa aacgtatgtt tgcctaatga atgtgatgaa ataaggtaaa ataacactgt
    48841 tttctgtgga taaacctgtg gatgttgtgc ataactgttg gggaaatctt tttaacaaaa
    48901 atagccaaaa taaacatata gacgaaaaaa ttgattataa taaacaaagt gagcatgaag
    48961 accaaaggag agaaaacatg aatatcaaaa ttatctcagt aggaaaatta aaagaaaaat
    49021 acctgatcca aggtatcaat gagtatgtca aacggctgaa tgcctatgca aaaatcgaat
    49081 tgatcgaagt tcctgacgaa aaagccccgg agaatttaag cgaagcgcaa atgagacaag
    49141 taaaagaaaa agaaggggaa cggatcttag cgaaaatcaa agaacaagaa tacgtctatg
    49201 ccttagcaat tgaagggaaa aatcctacaa gtgaatcttt tgctaaacaa atcgaccaat
    49261 taggtatcca aggaaaaagc caccttgttt ttgttatcgg cggctcttta ggactcagcg
    49321 aagccgtcat gaaaagaagc aatgctcaga tctcttttgg aaaaatgacg tatccacatc
    49381 aattgatgcg tctgatcctt gtcgagcaaa tctaccgtgc cttccggatc aatgcggggg
    49441 cgccttatca taagtgatgc ggtttttatc attgatccta aaaatcttag caagacaaaa
    49501 agtacgtaag aaagtaaaga ctaaatactt cggaggaaca aatgaataac aatgataggt
    49561 tattgcgatt gcgttatgcg attgatttga aagatacgga tttgattaaa gcttttgagc
    49621 taggcggtgt accactgact aaagaagaag ctcaggcggt actgaccaaa gtacaggata
    49681 agaacaaaga taatgcagaa aataatgtgt atgaaaaaac catcaacaac caagtttttg
    49741 acgcattcct aaatggcctg attctcttgg cgcgtggtcc gcaaaaagat aagccgatag
    49801 tagacacgcc gcaaaaaagc aaggaaatca aatatatcaa caatgtgttg ctaaaaaaat
    49861 taaaaatcgc cttgtctatg accactgatg atattttaga cgtttttgct gaggcagaaa
    49921 tctatccatc aaaaggcgaa atcggggcat ttttgagaaa agaaggccaa cgaaatttta
    49981 agccttgcgg agataaatat atgcgtaatt ttctcaaggg gttaggaatt tataatcgga
    50041 gaaaagtata aagaaatttc atgagaaatc aaaacaatgg ttgttttgat gagagctagt
    50101 ttttgtatga gattaaaata ttatcttaat cgaggagctg gattggtttt atgaatgatg
    50161 aatataagaa tgatgaagat aagatgcttt ttgaagagat agagaatcga tgtaggctca
    50221 attttgagct tcggggaaag atgtctttaa tacaacaaaa aaagtattta gcgaataaat
    50281 cagagtttac tctgggacat gttgaaaaat taatctcgga ttggattagt agtagaagcg
    50341 aatttacaaa aataaaacag ccgattaaat ttgacatgaa aaaacttttg ttaaataaga
    50401 gtgagatagg taatagagat caatatatta gagctaaagg gcaagaaata attgattcat
    50461 taggtgaaat gaggtcatac aattatttgt atgtaacaca tagagctgat ggaatggtca
    50521 ttactgtggg gaaatcttct tctaatgata tttttttaga tggagatctt ttttatcaac
    50581 tcaatacaaa tcacttgtct ggcactgaaa atataatttt aaggacggaa tatggcaatg
    50641 aaatatttgc aaaatatgat gagattttaa aaaattattt ggactgggct tggataattc
    50701 cggttgagtc aggagatgct aagaaactgg agagattatt gggcgatgaa ctaattaata
    50761 aaaaagtacc aattttaaat tattattccc atagacaata aaaggctatt tttcatgata
    50821 atactagtta taactgtaaa aatggaagaa aatctgggaa agaagttttt aaataagtgt
    50881 attgttcgat tttaataaat aataagcaat accatccgtc tgtgttgcgc aacatcgtac
    50941 tacaatgaat attttttcac aaaaagaaaa tcatccatcg aatgaatgga aggttttagt
    51001 atacacgagg ttaatgcccc ctcttttata atcagaggag tgaggttttt tctatgaatg
    51061 tttctatttt cttattgcta gtctagtttc tcttacgatg aaattgggat tctattccag
    51121 tttttattga tttgctgata aaataacttg aatggtggat ataaacatga taaataagag
    51181 aagaataaca aaacaaggtt gtgaaatgat tctcaaatga atataataga aagaaaaagg
    51241 aggaagaatc aatgaaaata gcaattgcag gcgctggcgc aatgggaagt cgctttgggt
    51301 taatgcttca ccaaagtggg aacgaagtat tattaatcga tggctgggca gaacatgtcc
    51361 aacaaatcaa agagcatgga ttacaagcaa attttaatgg taaagaggta gaagcaaaac
    51421 taccaatcgt tcttcaatcc gaagtagaaa aagaagatca agttgatctg attattctat
    51481 ttaccaaagc gatgcagctg gaaaaaatgc tgcaggatat ccaatcatta atcaaaaaag
    51541 atacagaggt cttatgtcta ttaaatggta tcgggcatga agatattatt gagaaatttg
    51601 taccaatgga aaatatctat attggaaata ccatgtggac ggcaggtctt gaaggtcctg
    51661 gtcaggtcaa attatttgga agtggttcag tagaattaca aaatttaggt gatggaaaag
    51721 aagcagctgc aaaaaaatta gcagacaaat tgtctgaatc aggattaaat gctcattttt
    51781 ctgacaatat tcactattct atttatcgca aagcatgtgt gaacggaaca atgaacggac
    51841 tatgcacaat cttagacgtt aatatggctg agctaggaaa aacatcgact gctcataaaa
    51901 tggtggcgac gattgtcaat gagtttgcca aagtagcagc agtagagaag attgaactag
    51961 atgtcccaga agtcattgca cattgtgaat cttgttttga cccggaaaca attgggttac
    52021 attatccttc aatgtatcaa gacttgatta agaaccatcg attaacagaa atcgattata
    52081 tcaatggcgc aatttctaga aaagggaaga aatatggtgt tgcgacgcct tattgtgatt
    52141 tcttgactga gcttgtccat gcaaaagaag atagtttgaa cgtaaaataa aggagagatt
    52201 gaatggaaac ttcacaaaaa atatcaccga aaatttttct gaataaagtc ctcgctggta
    52261 cagcaacagg aatcattatt ggattgattc ctaatgcagt attaggtgcc attttaaaat
    52321 attttagtgc gtatcccttt gcggtaacga tcgcacagtt agcagttatt tttcaactag
    52381 caacaccttt gatcattggt ggtttgattg ccttacaatt tggatttgat ccgatgagaa
    52441 tgatggttgt agccggagct tcttttgttg gttctggtgt agtcaaattc acacctgatt
    52501 tgggtgaaac gggtgtttac gttggtgctg gtacaggcga tattattaat acgatgctga
    52561 cagcatcgat tgctgtcggg ctgattttac tgattggaaa tagttttggg tcagtgtcga
    52621 ttgtgttaac accgattgtt gtaggtgtag gtgcaggttt acttggtttt tatttattcc
    52681 cttttgtaac agcaattact tctgcaattg gatcattgat taataacttc actaccttac
    52741 aaccgctgtt aatgtctatc ttgattggtt gttcctttgc ctttttgatt atctctccta
    52801 tttcaacagt agcaatcgga atggcaatcc aactagatgg tgtttctgct ggtgcggctg
    52861 cgatgggcgt agctgcaacc acttttgttt tagtagtgaa ctcttggaag gttaataagt
    52921 caggtgtgac aattgcgatt gctttaggcg ctatgaagat gatgatgcct aatctattta
    52981 gaaaacctgt gattcttatt ccttgtttag ttagtgcagt gattacagct attcctgtcg
    53041 ctctattttc tatttcaggt acgcctgctt ctgctggttt cggcgtggtc ggacttgttg
    53101 gtccgttggc ttctttagat gcagggctaa atggctttct tgttgttctt tgttggttag
    53161 tcatccctgt ttttgcggca ctaattactc aatttttatg cgagaaagta tttaaactgt
    53221 atgatcgaga agaagtcttc aaatttttag gctagtagat tttactaaga aattttcaat
    53281 caatggatgc gtaagtgaga tgtcaacaac atctgactta cgtttttttg cctttttgag
    53341 taggagattg atgctgacaa ctgaactctt cagtgccatt cgatttttta aaatgtagaa
    53401 gaaactcacc tttatgttat tgattgttca aaaggcaact agaataaaaa tatgtgttaa
    53461 aatgagaaaa aatttgattg ttggatgtat cgaataatca ctaaaaagta ggagaagaaa
    53521 atgatttttt tgcaaaaata tggtttttat tttttattat taggtgtgat tagtgattta
    53581 tcgacaccgt atatccttgg ccttttttat cccaaactga atcaaatgac taccgtaatt
    53641 agtgtgtttg gtgacgtaga tagtccagtc agacgtgctt tcttggtctg gtcagttgta
    53701 tctggacttt tttttgttct ttcgttgcct gcgttgtatc acctatttat tggaacatca
    53761 aaaacacttg caatacttgc tgttgcaaca gttggtttat atgggatagg tgattgtatt
    53821 tttactgggt tattcagtat caatacgaat gaaagctctt ggaatctatc gacttggatc
    53881 cataatatag gttctgggct aggctatgca ggctttctac ttttcccatt gttacttgtt
    53941 ctgctttatc gtcaaagtgg tcaaggtacg cttagccatt tttatcttgt tttaacagtt
    54001 attagtttac taattgcagg tctttacgga ttagcacgga ttccgtcgat tagtcagttt
    54061 gccttcttta agcaattggg cttctttcaa cgcttaagtt ttttctttaa ctatttgccg
    54121 atgatttgtt taagtttttt tcaactacga aagtagaaaa agcagtgtga agctgattaa
    54181 gtaaaagaat ttctctatgg gtaaccattc gtgtggatgt gttcgactaa gaatagagat
    54241 gaggagagcg aaaagcaagt tagtcttaac ttgttatgcg ttgtgctaaa tttcaggtag
    54301 tcattttttg aatgaataag aagaaaactt gaaagagggt gacttcatgt tagatgtgga
    54361 gcagatggaa atagaccttt ataatattat tttaaatcga aatacaagag aatgggaaag
    54421 aacacaattt gaagaggcaa aagaagacct agcaaaaatg tcgataaagc aggtgataga
    54481 aaaactagag gtcaacttgc gtccgctagc actacgagat aatttgacac cagatgcgat
    54541 ggatttttat ttaagaatca caggggagtc agcgagtgca aaggcttatg attatgccaa
    54601 acataagata acttcaccct tataccaaga acgggcgatt tttgccggtg gctgtttctg
    54661 gtgtatggtt gagccttttg aaacaaaacc aggtgtaatc tcagtgttat ctggttatac
    54721 aggtggagag accaaaaaac caaattacga tcaagtcagt ggtggatata ctgggcatgt
    54781 tgaagctgtt gagatcatat ttgatacacg tcaaataacc tatgaagagc tgttggagat
    54841 ttattggcaa atttcagacc ctacagatgc ctttggtcaa tttcaagatc gggggaaaca
    54901 atatcgttca attctatttg ttgttaatga aaagcaaagg caattggctg aaaaatcaag
    54961 agaacaactg attcaatcta accgatttag ccgtcctatc gttacagaga ttcgccaagc
    55021 aaagactttt tggccagctg aaaatcatca tcaacaattt tatcagaagc aacctaaaag
    55081 atataaaaag atcaagcatt cgcatcagct tcatttattt tttcagcgac atagatagag
    55141 gaaggttgtg gcgcaaagcg ttcagctccg acaaaataat gagcaactga caaaaatagc
    55201 ttttcatatt tttggacagt tatgaattat ttcgaggagt tgctttgaga acaccgagga
    55261 aaaggttgtg gcgcaaagca ttcagcttca agtcgcaagg aaacaggagg tatgacaagt
    55321 cttttgtcac aactcctgtt tttttactag cctttatttc catgtgaaag agaattcgaa
    55381 ttgtagaatc ttgatttttc tatggaattt tgtagagaat catcttgata attaatagac
    55441 acctaatcga attccacatt aatgatgaac taaattccgt ataaaagcgc aaacaataac
    55501 ta
//
LOCUS       DADQDV010000012        51519 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.012, whole genome shotgun sequence.
ACCESSION   DADQDV010000012 DADQDV010000000
VERSION     DADQDV010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 51519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51519
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.012"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            150..1208
                     /locus_tag="J8S10_000773"
     CDS             150..1208
                     /locus_tag="J8S10_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014372913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HAZ9629378.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
     gene            1227..2246
                     /locus_tag="J8S10_000774"
     CDS             1227..2246
                     /locus_tag="J8S10_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HAZ9629379.1"
                     /translation="MRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIVSAKDH
                     DAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVPSYSPN
                     AIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRIGLTEA
                     VLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQMINEG
                     FLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSFKPWET
                     IPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNEVSLPK
                     ARQLR"
     gene            complement(2348..3064)
                     /locus_tag="J8S10_000775"
     CDS             complement(2348..3064)
                     /locus_tag="J8S10_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAZ9629380.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(3033..3818)
                     /locus_tag="J8S10_000776"
     CDS             complement(3033..3818)
                     /locus_tag="J8S10_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAZ9629381.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            complement(3809..4558)
                     /locus_tag="J8S10_000777"
     CDS             complement(3809..4558)
                     /locus_tag="J8S10_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HAZ9629382.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            4856..5380
                     /locus_tag="J8S10_000778"
     CDS             4856..5380
                     /locus_tag="J8S10_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629383.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            5396..6895
                     /locus_tag="J8S10_000779"
     CDS             5396..6895
                     /locus_tag="J8S10_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HAZ9629384.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(6983..7585)
                     /locus_tag="J8S10_000780"
     CDS             complement(6983..7585)
                     /locus_tag="J8S10_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAZ9629385.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            7689..8645
                     /locus_tag="J8S10_000781"
     CDS             7689..8645
                     /locus_tag="J8S10_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HAZ9629386.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            complement(8950..9906)
                     /locus_tag="J8S10_000782"
     CDS             complement(8950..9906)
                     /locus_tag="J8S10_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAZ9629387.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            10080..10640
                     /locus_tag="J8S10_000783"
     CDS             10080..10640
                     /locus_tag="J8S10_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629388.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            10633..11457
                     /locus_tag="J8S10_000784"
     CDS             10633..11457
                     /locus_tag="J8S10_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HAZ9629389.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            11467..12084
                     /locus_tag="J8S10_000785"
     CDS             11467..12084
                     /locus_tag="J8S10_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HAZ9629390.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            12102..12785
                     /locus_tag="J8S10_000786"
     CDS             12102..12785
                     /locus_tag="J8S10_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HAZ9629391.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            13468..14751
                     /locus_tag="J8S10_000787"
     CDS             13468..14751
                     /locus_tag="J8S10_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HAZ9629392.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            14767..15654
                     /locus_tag="J8S10_000788"
     CDS             14767..15654
                     /locus_tag="J8S10_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAZ9629393.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            15671..16507
                     /locus_tag="J8S10_000789"
     CDS             15671..16507
                     /locus_tag="J8S10_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAZ9629394.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            16510..17133
                     /locus_tag="J8S10_000790"
     CDS             16510..17133
                     /locus_tag="J8S10_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629395.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            17130..18422
                     /locus_tag="J8S10_000791"
     CDS             17130..18422
                     /locus_tag="J8S10_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAZ9629396.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     regulatory      18781..18878
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            18994..19575
                     /locus_tag="J8S10_000792"
     CDS             18994..19575
                     /locus_tag="J8S10_000792"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HAZ9629397.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     gene            19578..20885
                     /locus_tag="J8S10_000793"
     CDS             19578..20885
                     /locus_tag="J8S10_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HAZ9629398.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            21301..21789
                     /gene="purE"
                     /locus_tag="J8S10_000794"
     CDS             21301..21789
                     /gene="purE"
                     /locus_tag="J8S10_000794"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HAZ9629399.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            21773..22906
                     /gene="purK"
                     /locus_tag="J8S10_000795"
     CDS             21773..22906
                     /gene="purK"
                     /locus_tag="J8S10_000795"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HAZ9629400.1"
                     /translation="MINLVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVS
                     DCPAAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTD
                     LLAITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKG
                     QYVLKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHN
                     NILHETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRP
                     HNSGHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENK
                     PDWQFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            22919..24214
                     /gene="purB"
                     /locus_tag="J8S10_000796"
     CDS             22919..24214
                     /gene="purB"
                     /locus_tag="J8S10_000796"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HAZ9629401.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(24336..25724)
                     /gene="ltrA"
                     /locus_tag="J8S10_000797"
     CDS             complement(24336..25724)
                     /gene="ltrA"
                     /locus_tag="J8S10_000797"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HAZ9629402.1"
                     /translation="MRRPQKTRKLGYHQRASVEHEGYDEVRSTSCGEQRKQDGVENLF
                     GRILDRNNLNQAYLQVVRNKGAAGADGMTVDQLLPYLKEHREELLSNLRQGNYKPQPV
                     LRVEIPKPNGGVRKLGIPTVIDRMLQQAINQVLQPLFEPEFSDNSYGFRPNRSAHDAV
                     KKAKSYYEQGYRYVVDIDMKAYFDTVNHDKLMYFIERKVKDKQVLKLIRQYLMSGVME
                     NGLITTTEEGTPQGGNLSPLLSNIYLNEFDQVLENLGHKFVRYADDCNIYVRSKRAGQ
                     RVMKKSIQFLEEQLKLTVNREKSAVGSPLKRKFLGFCILPTKKGIKIRPHAKAKQRVK
                     SKLKQLTKRNRGRSIQLILKEIKQLMTGWINYYGIGEMKEFMRELNGWLKRRIRQYIW
                     KQWKNPRTKRKNLIRLGIDKAKAYEWSNTRKGIWSVSKSHILHRSLTDKELARQGYED
                     ISLKYQFVHSTY"
     gene            complement(26293..26670)
                     /locus_tag="J8S10_000798"
     CDS             complement(26293..26670)
                     /locus_tag="J8S10_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629403.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            26926..27654
                     /locus_tag="J8S10_000799"
     CDS             26926..27654
                     /locus_tag="J8S10_000799"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HAZ9629404.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            27654..27908
                     /gene="purS"
                     /locus_tag="J8S10_000800"
     CDS             27654..27908
                     /gene="purS"
                     /locus_tag="J8S10_000800"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010758866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HAZ9629405.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            27910..28581
                     /gene="purQ"
                     /locus_tag="J8S10_000801"
     CDS             27910..28581
                     /gene="purQ"
                     /locus_tag="J8S10_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HAZ9629406.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            28582..30804
                     /gene="purL"
                     /locus_tag="J8S10_000802"
     CDS             28582..30804
                     /gene="purL"
                     /locus_tag="J8S10_000802"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HAZ9629407.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNEMDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            30789..32228
                     /locus_tag="J8S10_000803"
     CDS             30789..32228
                     /locus_tag="J8S10_000803"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010768528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HAZ9629408.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            32260..33303
                     /locus_tag="J8S10_000804"
     CDS             32260..33303
                     /locus_tag="J8S10_000804"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HAZ9629409.1"
                     /translation="MANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGFGGC
                     FDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEPLYF
                     LDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFAVGI
                     AEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKKTLG
                     EELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSWPIL
                     PIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVQESKVKEIVHEIEQAGEKVYEIGKVIA
                     KEKHRVVFIGEER"
     gene            33300..33878
                     /gene="purN"
                     /locus_tag="J8S10_000805"
     CDS             33300..33878
                     /gene="purN"
                     /locus_tag="J8S10_000805"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HAZ9629410.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            33875..35410
                     /gene="purH"
                     /locus_tag="J8S10_000806"
     CDS             33875..35410
                     /gene="purH"
                     /locus_tag="J8S10_000806"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HAZ9629411.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALAFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            35426..36700
                     /gene="purD"
                     /locus_tag="J8S10_000807"
     CDS             35426..36700
                     /gene="purD"
                     /locus_tag="J8S10_000807"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HAZ9629412.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            36822..37736
                     /locus_tag="J8S10_000808"
     CDS             36822..37736
                     /locus_tag="J8S10_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HAZ9629413.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(37869..39434)
                     /locus_tag="J8S10_000809"
     CDS             complement(37869..39434)
                     /locus_tag="J8S10_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAZ9629414.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(39427..40878)
                     /locus_tag="J8S10_000810"
     CDS             complement(39427..40878)
                     /locus_tag="J8S10_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAZ9629415.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(40892..41908)
                     /locus_tag="J8S10_000811"
     CDS             complement(40892..41908)
                     /locus_tag="J8S10_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAZ9629416.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            42128..43216
                     /locus_tag="J8S10_000812"
     CDS             42128..43216
                     /locus_tag="J8S10_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAZ9629417.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            43270..44796
                     /locus_tag="J8S10_000813"
     CDS             43270..44796
                     /locus_tag="J8S10_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HAZ9629418.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            44798..46003
                     /locus_tag="J8S10_000814"
     CDS             44798..46003
                     /locus_tag="J8S10_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAZ9629419.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            46260..47237
                     /gene="guaC"
                     /locus_tag="J8S10_000815"
     CDS             46260..47237
                     /gene="guaC"
                     /locus_tag="J8S10_000815"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HAZ9629420.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            47501..48925
                     /locus_tag="J8S10_000816"
     CDS             47501..48925
                     /locus_tag="J8S10_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HAZ9629421.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            49386..50495
                     /gene="pdhA"
                     /locus_tag="J8S10_000817"
     CDS             49386..50495
                     /gene="pdhA"
                     /locus_tag="J8S10_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HAZ9629422.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            50498..51475
                     /locus_tag="J8S10_000818"
     CDS             50498..51475
                     /locus_tag="J8S10_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HAZ9629423.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
BASE COUNT        16256 a         8997 c        11273 g        14993 t
ORIGIN      
        1 aatcacttta cataagtttc aaaagtttct ttaatttcct attgttcaat aagtaacaat
       61 gtaaagataa aattaaaaat gttaatacgt attagcaaaa taaaagcttt ttttattgtg
      121 aataaatgaa cataattagg aggagaaaga tgaacttatt tgacattttt cgatcgactt
      181 tgacagatat gtcgattgtc agtgcaatca cttcaacagt ttttattata ttattagggt
      241 ttgtttgtag aaaaaagggg attttttctg aatctgttgg aaaaattcta tcgaaagtcg
      301 tcttaacagt ggctttgcca gcactggcat ttcgagcttt catgcaagat atcaatacag
      361 aattactgat gcaaggaatc aatgtcttga tttggggatt agttatttat attattctta
      421 ttctagtttc aaaacctttt ttcttaagct ataaagggga taagcaaaca acgttgcgtg
      481 tcctgacgat ctttggttct acgacctttt tcggaacgcc tatcgtcagt gcgatttatg
      541 gtcctgtcgg cgtgatgtat tcctcaattt tcaatattgg ctaccgaatc tttttgtatt
      601 cttatggata cataaaaatg agtggcttga agatggaagc taaaaatatc aaagcgatgt
      661 tcgtcaatcc aatcattatc gctacttttg ccggcctttt catttggctg ttccaagggt
      721 atctgccaca agtgtcagtt acaggtgcag aaggagagat aagccaagta gcgtttttgc
      781 gaattgacca gactgcaccg tggctatttc agccgatgga ttatttagct ggtttaagtt
      841 caccattggc gtggctagca atcggcgcaa cattaggtga agtaagcttc aaaaaagctg
      901 catctgaaaa aacttcatgg tattacagtc tagtcaaagt ggtatttgta cctgcattga
      961 atatcgtgat tctagcagtt ttgacggcaa cgaatattct accagtcaat tttgaagcac
     1021 tggcaacaat cgttatcatg atggctacac cagctgcaac agtggcagca gcctatgcta
     1081 tcagttttga tagggaggca cttttagcct ccaatgcatc cttactgtca actatttttg
     1141 ctgtggtact gacacctgta tggatcgttg tattacaaat gattcatggc ataggtttat
     1201 tttcataaga aatggaggaa gaaagtatga gaatcgcatg ttacggtgtt cgtccgaacg
     1261 agatagattt ttttgaaaaa ttgaatattt accattatga tctcagtctt tatgaagaac
     1321 tgttgacaca tgacaatatc gtgtcagcaa aggaccatga tgctgtattg ttgaggggaa
     1381 attgtatagc agatgagacc aatcttgcaa aaatgcagga atatgggatt cgttatgttt
     1441 ttacacggac tgtgggagtc aatcatatcg atctacaagc ggcagctgat tttggtatga
     1501 cagtagcccg tgtaccatcg tattcgccaa atgcgatagc agagttatct ttgacttttg
     1561 ccatgatgct tttgagaaat actgcgtata cgacgatccg aacatctttc aaagattttc
     1621 gagtggatga gcaaatgttt agtcgtgaaa tcagaaattg cacagtaggg atcataggaa
     1681 caggcaggat agggttgacg gaagctgttt tgtttaaggg actaggagcc aaagtgatcg
     1741 gctacgatat tcatcagaca gaagctgcta aaaaagtatt gacgttccac tcgcttgaag
     1801 agttattagc caaaagcgat attgtcagta ttcatgtacc tcatatccca ggtgaaaacg
     1861 atcaaatgat caatgaagga tttttagctc aaatgaaaaa aggtagcatc ttgattaata
     1921 cagcccgtgg agagcttcaa gataatgaag ctattttaag agctttgaaa agcaatcatt
     1981 tagctggttt tgcaaccgat gtttttgcaa atgaaacaga ggtttttttc cgatccttca
     2041 agccatggga gacgattcca gaccctgcta tccagcaatt agtagaaatg taccctagag
     2101 ttcttgtaac cccgcatgta ggttcaaata cagatgaggc attatcaaat atgatttcga
     2161 caagtttcga gaactttcgt gaaataatag aaactggaaa aacgaaaaat gaggtatctc
     2221 ttcctaaagc ccgtcaatta agataagaaa acatggatat tcgtcaataa aatgtttaaa
     2281 aatagtccaa gtaaacagtt gttacttctg tatacttgga ctattttgta tgggataatt
     2341 cgatgactca acagtaatct gtgagctttt tccgcccatt ctttgtcaat tcataacagg
     2401 ttagcggccg gccgatttcc aaatatttga ttctttcgtt caatatatct tgttctacta
     2461 aaaaattcaa atatttcttg acggatatac gtgacagtga gcttttttga gccagttctt
     2521 ttgttgaaaa aatagtatct tcttttagaa taaatgcact tatttttttt aaagtcagtt
     2581 ttgacagacc tttaggcaaa tcgatgaatg atggtatttc gtgaatggga gtggtgtggt
     2641 tgaatacttg atcgatcaat ttctgatcgg ctttttcagt cgtttggatt gtctgagaga
     2701 aagcaagata cttttcgatc gccagctgaa aacgttgcaa agtgaacggt ttgatcaaat
     2761 aatctaaggc accgtagcgg atcacattct ttatggtttc gatatcatct gcagcagtga
     2821 tcaaaatcac tgggatatca tttccttgct gtctaagcca agataaaaaa tggataccac
     2881 tttcgccagg catgtataca tcaagcagca gcagatctgc gtttttttgt ctgaaatatt
     2941 tttttccttc ttctacattt ctgaaacttt cgattacgtt catattaggg atgctttcca
     3001 caaaagtacg attcaattct gcaaccattg gatcatcttc gattatcagg acatttgtca
     3061 tcattttgat cttccttttt tggtaattct agatagacga ttgtaccgcc atttgtttgt
     3121 ttggaaaatt ctaaaaatcc accgtggcgt ttgacgattg aatggatgag attcaatcca
     3181 aacccacgat tgattccctt cgtcgaaaaa cctagcgtaa atattttttc tgagatttct
     3241 tctgatatcc cgacaccgtc atcgcagacg gtcacgatga atacttcagc ttctgtgtca
     3301 tagtttaaat gaatccggac ctgtccgttt ctttcatgtt tttgtagcac ggcttctttt
     3361 gcattatcaa gtaagttccc taacacttgc aaaagtgaat ggatggagtc atccatctcc
     3421 attttaggga taaaagaatc gctttctaac agcatttcaa cagattgttc tttggcttcg
     3481 tttattttgc ctaataaaaa accggcaatt gcaggtactt tgatcagact tgagacttgg
     3541 ccaatctctt ttttataatt ttgatttagc tgctggataa aatgggtgac ttcttcatac
     3601 ttcttcaaat caatcaaacc agaaatgaca tgaagtttat tcatgaattc atgggtttga
     3661 gctctcatgg agtttatata ttgtttcgtc cccccaagct cctccattaa tttcattact
     3721 tctgatcgat ttcgtaaagt tgcgactgct cctaaaaaac ggtcattgct aaaaagaggt
     3781 gtaacgctag aaatagtttc tatcccattt aaatacatgg attgagtccg aacggtcgtt
     3841 tgatgctcaa tcgtctcttt aaacaaaacg tcatatagat tatcactgat ttttttccta
     3901 cttcgaaatc caatagctgc tctgtttggt agaaaatgtt ttttgcaggt gtattgatca
     3961 agaggatagt tttatcagaa gagatggcta agattccttc atctacttca ttttcgataa
     4021 tcgttttttc acttaactgt tctgctattt cttgtggttc aagtccaagc agtacttttt
     4081 tcattttttg ggcaagaaaa acggcgccta tgatgcctac gctaagtcca ataatcaatg
     4141 aaaaaacaat cattttttgt ccatctttga cttgattgtc aatcgtgttg tttgttaagc
     4201 caacacaaac tgcaccaata atctcttgat cataataaat agggacgaaa tagcggaagc
     4261 cgaaccctaa cattccttct ttttcagaga aaaattcttg tcctccaatc acttttttca
     4321 catcttcatg acttgagaaa ggaagaccga tgtaacttgg gtctgcgtga gaatatcgaa
     4381 tgccttcagg gtccatgaca acgataaaat ctaaattcga tgcaatcatg atttcatttg
     4441 ttattccttg aatcgcatgt gtcgggtcac cagtctgcag ctttttttgg atgagtttat
     4501 cattggcaac gattttagca atgctagaga ttttatctga cacactagat cggttcatcg
     4561 aaagaataaa attcctgatc aatatggcag aaacaatcaa agaaacgaat gtggagaaac
     4621 aaacgacaag gatgatcgtg ttctggagct ttaatggttt tttcttaaaa aaaggaaaca
     4681 taggctacct cgaaagaatt tattgtgaaa attttaacat gaaaacaaaa atttaacaaa
     4741 ttgtcaacga taaacacaac cttcctataa aaaacaccac tgagtcggta aaagaagcta
     4801 tacagaattt tcaaacattg gtatgataga cgtagaaatg gaaggaggcg tgtatatgat
     4861 agggggaatc gcacttgaga cgatttattg gtatacattg ctgatttgtg caggattggc
     4921 agtcctattg attatttttg gagatgtatt cgattttgat ggcccgcttg atccgatgct
     4981 tattatccct tggttaactt tcacaagctt atttggtttt ctaggtgagc gtttaacaga
     5041 tcaatcatct ttatttttat ttattgctag tggaggcata tcgatagtgt tggtattttt
     5101 gcttaatttc tatatattga tgccgatgaa acatgccgaa tcaacgatgt cgtcttctga
     5161 aaaaactctg gaaggacaag tagctgttgt gatcacaccg atccctgtac gaggtatggg
     5221 agaaattcag ttgaaaagtg ttaccggttc cattagtcgt ccagcttgtt tttacagccc
     5281 ccaagaacag acagctgagc ggggaacgaa agtattgatc attgagatca aggaaagaat
     5341 ctgttatgtc atgccttatg aaagcatgat aaaagcttaa aggagcgtgt gttaaatgga
     5401 aataccagtt gtttttatcg cgatcgcaat cgcagctttg attttactga tgttgctgat
     5461 cgtctttgta gcgaagtacc agacagcaaa accggatgaa gcgttgatca tcagtggaag
     5521 ttatttagga agcaaaaatg tgcacattga tgaaagcaat aacaaaatca aaattgtgcg
     5581 tggaggtggc gcattcgtct tgccagtttt tcaacgttcg aatcggatca gtctattatc
     5641 gagtaaattg gacgtctcca cccctgaagt gtatacggaa caaggcgtac cggtgatgtg
     5701 tgatggtact tcgatcatca aaatcggttc atctgtagaa gagattgcta cagcagcaga
     5761 acagttttta ggcaagacaa gagaagaact ggaaaatgaa gcaagagaag tattagaagg
     5821 acacttgcgc tcgattcttg gttctatgac tgtagaagaa atctatcaaa atcgcgataa
     5881 gttcagtcaa agcgtacaag aagtcgcttc tgtagacctt gcaaaaatgg ggttgatcat
     5941 cgtttctttc actatcaaag aggtcagaga caaaaacggt tatcttgact ctttagggaa
     6001 accaagaatc gcccaagtca aaagagatgc agatatagca gaagcggaag ctctaaaaga
     6061 aacgcgtatc aaaaaagctc aagcagaaaa agaatcacaa gcagctgaat tacagcgaca
     6121 aacagagatc gcagaatcat taaaagaaaa agaactgaaa ttagcaacct acaaacaaga
     6181 acaagatgtt gctaaagcaa aagcagacca agcctacaat ttagaaagtg cccgagcaca
     6241 acaacaagta atcgaacagg aaatgcagat taaaatcgta gaacgtcaaa aacaaatcga
     6301 actggaagaa aaagaaatca cacgtcgtga aaagcaatat gattcggaag tgaagaaaaa
     6361 agcagatgcc gatcggtacg ctaaagaaca agaagcacaa gctcaaaaag tcaaagaagt
     6421 gactgaagcc gaagcagaac gattccgtgt ggaagcactg gcagaagcgg aagccaataa
     6481 gacacgttta gctggacaag cagaagccga agcagcacta gcaaaaggaa aagcagaagc
     6541 cgaagcaaaa caaaagatcg ccaatgcctt caaggaatat ggcgaagcag ctgtcttgag
     6601 tatggttatc gatatgctac cgcaattgat gcgcgaagca gcacagccgc taggaaatat
     6661 cgaaaaaatc tctgttgtcg atacaggaag cagttcagga gaaaccagtg gagcgaaccg
     6721 agtgacaaat tatgccacaa atttgctttc ttctactcaa gaaacactaa aagcgacaac
     6781 aggacttgac ttgaaggaaa tcgtagagaa tttgtcgaca cgtgggacta ctagccaagt
     6841 aaatatgtat gaagcgccaa aagaggcaga acaaaactcg atgaaggaag aataaagtag
     6901 tacacttcac cgttcaatca aaaatggagg aagacttttt aaagttcttc tctccatttt
     6961 tttattttat tgcaaaagaa aattagtcct cgctattttt cttttgtttt tggatcttag
     7021 cttctatctc ttgtaaattt gttcttagca atcgttcttt cttttggagt tcgaccaaat
     7081 cttctgatag ttcttccttc ttttctgttt caggaggacg aagaaagaaa ttgataccga
     7141 ttgcaatgaa tgtccctata aaagtatcta gtacacgttg gatagcatac aaagcggatt
     7201 cgccttgagg gatgctcaac gcaatcagca acaacgtagc tattgcggaa atgataccgg
     7261 aattattgtt aataccatct gacacgacga tcacaataat aactagaata ggaagcaaga
     7321 tcaattctac caaaaaatca ttgtgaaaat agcttttgac aaaaaaataa atgatagcta
     7381 atgtaccacc taatgtattg ccgatgatcc tagactttcc aaaagaaacg gttgtagtca
     7441 agtcctgacg caaagaaaaa acagcagata atgcagcaat catcgggatt cctcgttgag
     7501 tcaaatgaaa aaacaagata cataaaaaaa cagctaaggc acttttgatc gtacgcatac
     7561 ctagtcgaaa acggccaaat tgcatagaga ttctcctttt tggtcttttt actatcatac
     7621 ctaaactttt gtctgatagc tagtttttca ttattcaagt ataattaaaa taaaaaaggg
     7681 ggaagtaaat gcgtatagga atgcgaacag tcaaaacagt gatcagtgtc ttcttttcga
     7741 tggtcacagc gggtagctta tcgctgttgt attggccagc tgcagggatc attgcattat
     7801 taagtgtagg aaataccaag cgctctacat tgcgtacggg catgaatcga atcgcagcct
     7861 ttatattagc tacggcaaca gcactgttca gtttttttgc tgttgggtat actatttttg
     7921 gcttcagtct ttttttattc ctgttcatcc cgcttgcctc tcgcttcaaa ttaaccgaag
     7981 ggatagtagt aaattcggtt ttggtcactc attatttagt ggaggaaaac atgtcttggc
     8041 agctgatcgg caatgaagcg ggattaatgg cgattggatt agtatttgct ttgcttgcaa
     8101 atgtttacat gccagatcgt acgaagcagc tgaaggaaaa ccaaatacag atcgaaaaag
     8161 aatttcgaaa tattttgaga caaatggcag aatttctttt atcagaaaat aaagaagatg
     8221 tgcagatcaa atgcgaacat ttactgacat tcattcgcga aagccaagaa gatgccagag
     8281 aacatcaaga aaactactgg ctcagacagc cgctatacta cgaaacttac ttctctatga
     8341 gaagagcaca ggccaatgtg attaaagaca tgctggaaaa tctagagaga atccagcaac
     8401 cagcttatta tggaaaacat atctatggtt tattgattta tactgcagaa acattttcag
     8461 agtcaaatga tggcagacaa attttaacac gtattgaaga agtttatgta ttgtatcggc
     8521 aaatgcctct gccgactagt cgccctgaat tcgaggatcg agcagaattg ttccagtttt
     8581 tgcagtcttt taaaagtttt attgaaatca aggcagaatt ctcccaacaa aaaatccaaa
     8641 aatagaggtt gtgaattcag ctaatattca ggtcaaaaag ctgatttcac aacctcttct
     8701 ttaaacggtg ttctcctgtc aactcctcgg tcacaagtca caatattcaa caaacatgag
     8761 aagctgtttt ttgaaattgc tccttgtgac tcggagctga acggtaggct cacaacctct
     8821 ttcttaaacg gtgttcaaaa gctttcctct gcggtaataa gtccagccaa acgaaaaata
     8881 ggaggagcta tttttgtttg gctgttctta ttacttgatg cagaacagct ttttcacaac
     8941 cttttaaaat tacatatttt tccatagaac ttgcatttga tccaagattt cgatgacatc
     9001 ttttgtcaag aagagagagc gattgggcaa gtcaccttca atcatgtgta ccatattctt
     9061 tatttcgtaa ttcattgctt cagatgtatt cccgctttcg atgaattcct ttgtaccatc
     9121 tgtaaataag atctccgcac gatcagcacg cgggtaatca gcaatcgtca cataaccgtt
     9181 ctcaaaggca acgataccga cttttggcat ttttgcctga aaagtcaagc tgacagcagc
     9241 aagttcattt tctttgttac gcaagatagt gacggattgt tcgtccacgc ctgtttcaaa
     9301 aggaaccatt gtagaggcaa ctacttcagg ttgagagctc aaaaagaaac gagcgaaaga
     9361 tacagcatac gtaccgatat ccaacagagc tcctccagct aattctggat tgaagaaccg
     9421 gtttttaggg tctggttctt tgtaactgcc gaaaggtgct tggatcattt ttaaagcccc
     9481 cagttttcct gtatccatta ttgagcgtaa ctgctgataa agtggcatgt tgaagattgt
     9541 catcgcttct gctaagatca aattcttttc ttctgctaag cgcatagcgt cagccagttc
     9601 ttttttattc atcgtgatgg ctttttcaca tagaacgtgt ttgcctgctt ccaatgctgc
     9661 caagatatgg tcgatatgct gtctatttgg tacagcaatg tacacgatgt cgatttcagc
     9721 atcgtctaac atttcttgat agcttccgta agcttttgga atattgtaac ggtgagcgaa
     9781 gttttccgct ttttctgaag ttctggaagc aactgctgtt agttcgctcg tctcttgatt
     9841 gaagctttcg gcaaactcat gtgcgatggt accaagacca acgattcccc attgatattt
     9901 tttcatctga aaacgctcct tcatagttgg attgagtttc ttgtctgtct attattataa
     9961 caaaaatcac gaagaataaa gaggagagga cttgaaacat taaaaaaaat gaaagcagcg
    10021 atttaagagg tgctttttga tcaaaactta agtagaatag ttaaaaggag gggataaacg
    10081 tgcatcaagt atatattgat cttattatga gtgtattatt agaacagttt gaaactgaaa
    10141 aaaatttttt agatgaatac ttgctgatca gtccagaaca atggcaaaaa tggaaagatg
    10201 gcgagaaaaa tctgccatct gaagcgatgc agaaagtaaa aaatcttttc actgattatg
    10261 aatggatgct aacgcaaaag attttgcgtc aaacgattat ttttcccgaa aaacgaaacg
    10321 ttgccgttgc agagtacaag caaatcaaaa cacgcatcgc gcaaaaatgg cttagcagca
    10381 aagcagcaaa agtcgagctg atccctttga aaaataatca gcaggctggt agataccttg
    10441 acttgaaagt aagtattcaa tatgatgaat ggggctatga tgatattttg aattttcgtc
    10501 tgccagcaga tgttcaaaaa cagatcgaag gagaaaaaat cgaacttctc gattgggtga
    10561 atgaaaatct ggaagaaact tacgttcatg aggcgaatgg ggaacgtgaa gaacaacgaa
    10621 aggatttttc aagtgaataa atttttagga tttggagcag ttgtgattat gatcgcagca
    10681 atgggctatg ttatttttag cgatgatgat tcgcatgttc aagccggcaa tcaagcagtc
    10741 gaacgaacaa gcaccaaaac aactgctagt aaagaaaaga acagtcaaac aaccagcagc
    10801 aaggtaaagg acaaagaaac aaaagatcgt acgtccaaac aattgccaga tgttaaaaca
    10861 gacgattgga agctagtttt ggttggtcca gatcacaaat tagaaaaaga aattgatgag
    10921 tctactcaat tggcatcatt aagtaacgga tacttgatcg acaaacgcat tgctccagaa
    10981 tatgaagcat ttgccaaggc tgctgaagca gctggatttc cattagtgat ggtctcagct
    11041 taccggtctg tatcatccca acaacaagtt ttcgaacaaa atgtccaaga tgtgatgagt
    11101 cgtcaaggtg tatcagaaga ggaggcgaca aagattacta aagaaacgat tacggagcca
    11161 ggatacagcg aacaccacac aggtctggca gtcgatgtcg tcgatcaaaa ctggtacaac
    11221 agttatcctt ctactgtatt ggatgcaagt tacggagatc agcctggagc taaatggatc
    11281 gcagataatg ctgcgcagta tggatttatc gttcgttatc caaaaggaca cgaagatata
    11341 actaagatca catatgaacc ttggcactta cgttatgtcg gtaaagaaaa cgctgagtat
    11401 atcaccaaac accaattgac gctagaagaa tatctgaatg aattaaatga aaagtaggaa
    11461 ttgatcatgg cgaaaaaaaa gtggaaaaag caaaagcgca agaatatccg ttggccagca
    11521 gtggttgccg gtgtagcagt gatactctta gcctttgttt tttccttgaa gaatctgtct
    11581 tctcctttta ctgataatca gcaagaaaat gaagcgcaat cccatcagca atttattgaa
    11641 cggcttgttc cgcatgccca agaactacaa gatggttatg gagtgcttcc tagtatcatt
    11701 ttaggacaag ctatattaga atcaaattgg ggaaaaagta ccttggctag caaatacaat
    11761 aatcttttcg ggatcaaggc ttatggggat cagaagaaag taagcctgga aacaaaggaa
    11821 tttgttaacg aagaatggat aactatccaa ggagacttca aagtgtatga ttcatgggaa
    11881 cagtccatgg atgaccatac acaactgttc gtccaaggag tagattggaa tcctgcgctg
    11941 tatgaaaaag tgattacggc caccaactat caggaagccg cacaagcatt gcaagatgca
    12001 ggttatgcga cagaccccgg ttatgcgcaa aaaatcatcc aggtcatcga gacgtatcaa
    12061 ttgaatcagt atgaccggag atagcaaagg agaagtggct gatggcagaa caatttacgc
    12121 cagaaatcat gacggaattg agaaaagata tcgtaagagt accggaaatc attttagaag
    12181 caagcgggat caagatattt ggaaaattga tccgttcgat catctttact acggatattg
    12241 cgatcatacg taatacaaat gcgaatgcag taattgctgt gtatcctttt acacctcatc
    12301 cagcgattac taaaagcatt attgaggcag ctgacattcc agttttctcc ggtgtaggtg
    12361 gtggtttgac acaaggtgct cgttcttcct acatgagcat gttcgcagaa gcgcaaggtt
    12421 cgttaggggt cgttttgaac ggtcctacgc ctttagagac agtaaaagaa gtttgtcgag
    12481 tagttgatat tccagttatc agtacggtaa cgtcgaaata tacagaaata gatgaaaagt
    12541 tagcagctgg tatttcgatt atcaatatca gtgcaggtaa agaaactgca gaagcagtac
    12601 gccattttcg taaaaaatat cctgaacttc ctatcattgc gacaggtggt ccaacggaag
    12661 aaagtattgc tgagaccatt caagcaggag caaatgccat cacatatacg ccaccaagta
    12721 gcggagagct ttttagtcgt aaaatggaaa aatatcggga aactgagaaa aagaatcatg
    12781 aataacaggt gagaatcaaa agacgaggaa gagcagatag tggctcttcc tcgtcttttg
    12841 tactccagta ctatttgttc agaattcaaa aaaaagagaa atttttttgt ttttttacct
    12901 gtaatgtaca taagaagagt taaaaccttt tgttattatt agcattctaa caaaaaaatg
    12961 tcttgattta ttgaagcgct ttctatagaa tgaaaaacga ataaaaacta aaaaaggcac
    13021 ccgacaattt agtagcagct aaattgtcgg ggcttgaaaa gtcagcggga actgaccaat
    13081 caagttgcca tagtcaatgc ttgtgcatcg acgtgtatat tgtacctaat ttcatacaga
    13141 attactagtt atttttctgt tttttaggga agagcgcaca cgaagaagca tgcttattta
    13201 gctatgtcaa ggatattggg cagttgtctg atatcctttt ttctttgcgt aattatcctc
    13261 ccatcattga agcaagaagt gtttttagcg atgaaagaag aatcagcact atctaatttt
    13321 tcttgaaagt attgagttgt tcatcctagg cagaacgata aggcaagtct tggtttttat
    13381 tccccttgaa aaagatcgtt taataaatat gttctgtata aaaatacagt atattgaaaa
    13441 ataacaatgg aagtagaggt gcagagaatg aagaaaagaa tgagaatcat cttagcttta
    13501 agtgttatgt tattcttctt gacggcttgt gggcaagaag atgacaaaaa aatcacgctg
    13561 aacatggctt ggtggggttc gcaagtccga cacgatgcaa cagtaaaagt aatcgagctt
    13621 tatgaagaaa aaaatcccca tgtgacgatc gattatgaat tttatgatta tgaaggatat
    13681 tacacaaaat taggtacact agcagcatca gatgatatct gggacatttt ccaactgaac
    13741 aatcaatttc ctcaatacat caatcagatt gaaccattag atgaatatgt ggagcaaggg
    13801 ataattgata tttctaatgc agatgaatcc tatttagcaa cgacgactta cgacgggcaa
    13861 ttagttggac tgtctaacgg ggtgaattcg tttgcgattg cttacaataa aaatatattt
    13921 gaacaattaa atatccctga accagcttca aattggacat gggatgaatt tgaacaaatc
    13981 agctatcaaa tcactgaaga attaggaatc tatgctattt caagattcga agattttata
    14041 gctggctgta ttattcaaat accacaagtt gagaaaggat tgaattttta taatcgggaa
    14101 gatctatcta acagcttggg atttgaaaat ccagactatc taacagattt tttccagctg
    14161 cgtaaaaatc tggtagacaa aggggcccat ccagaaccag gtggtggagc tgcaagtacg
    14221 acggatctgt cttttcaggc ggttagggat agagaagcgg caatggtgtt tctatcaagt
    14281 aaccagttga cagaaatatt gtcaggggct cctgaagata tggagattca gttgattaat
    14341 ccacctcgca gaaaagcaga tggagaatct ggtatccctt tacgttcttc gcaaatgctg
    14401 agtatggcaa aaagctcagc ccataaagaa gaagctgcta agtttattga tttctttcaa
    14461 aacagtgaag aagccaatga aattttaaaa ggagaacgtg gtgtaccaat catgtcgaat
    14521 attcgagaac agctcgctcg tgcagatgat gcaactttgc aagcgacatt tgattattta
    14581 gaaatgattt ccgatatgga caacggcgaa gtgaatgtct ttgatagtgc tttgaatccg
    14641 gaaattcaag accaatacaa tcttttagtt gaaaaagtca tttatgaaga agtaacagca
    14701 gaagaagcag cagagagtct ttatgagttt gcgtcaaaca ttctaggata gcagcaggag
    14761 gaaggcatga aaaaagaaaa actaaaacgg ttcttggatc aagacaatgt ggtcggttac
    14821 gtatttgctt ctccattcat cctaggattt ctattgataa cagtgatacc gatgatcttg
    14881 tcactttatt attcgttcac cgattatcgt ttgggaaatc cagtctcatg gatcggcttg
    14941 gataattata taaagatgct gagtgatgcc cgttttttga actccatccg agtcactttt
    15001 ctctatgtat ttgcatctgt acctgtgaaa ctgatctttg gtctattgat tgcttatctt
    15061 ttaacgagga atatcaaagg aacgactttc tttcgttctt tgtattatgt gcctagtttg
    15121 atcggtggca gtatttctat cgctctagtt tggcgggagt tgttttctaa aaacgggtta
    15181 gtgaatattt tcctggaacg attaggcgca cctgcgcttt cctggtttag cgatcaaaaa
    15241 ctggtcatga tccctcttgt tttgatgtct gcttggcaat tcggttcggc aatgatcatc
    15301 tttgctgcag gtatcaaaga gatcccaggc tcgtattatg aagcggcaga gatcgatgga
    15361 gcgaacaaat ggcagacgtt ttacaagatc acgttacctc ttctttcgcc gatcattttg
    15421 tataacttgg ttatgcagac aatcgcggcg tttatgactt ttacgcaggc atttatcatt
    15481 acccaaggtg gtccgaatga tgccacgaac ttttatgctc tttatgtgta taaccaagct
    15541 ttttctttta attctatggg gtatgctagt gctatttcgt ggatcatgct gttgattatg
    15601 ggagctgtca cctttctgat tttcaaatca tcaaaaaaat gggtcgttgt gtgaatgaga
    15661 ggaggaagaa atgaataata cagtaacgaa atggtttcaa tacggtttta ttttgctatt
    15721 aggtctagtc atgatttatc cggtcttatg gatgatcgca ggttctttta aaacggatca
    15781 agagattatg agtggttcgc tgaatttgat tccagagact tttcaatggg aaaattacgc
    15841 aaaaggatgg gcggggtttg ctggaatttc attttttact ttctttagga attcgtttgt
    15901 catctctgca gtttcgacga tagggacagt tctgagctcg acttgtattg cttacgcatt
    15961 atcgagaatc gatttcaaag gaaaaagatt ctggttcgtc gtcatgttag taacgatgat
    16021 gattcctgca caagtgattt tgattccgca gtttattatt tacaatcggc tgaatttggt
    16081 tgggacgtat gtgccgctga ttttaccaca tttttttgga caagcatttt tcatttacca
    16141 gatcatgcaa ttcatggtca gcatccccaa agagttagat gaatcagcga ttattgacgg
    16201 atgcagcaag tatagtgtct ttaccaaaat tatttttcct ttgctgaaac cttcgatcat
    16261 cacgacgatc atcatccagt tttattggaa atgggacgac ttcatgggac cattgattta
    16321 tttaaacaag ccgagatctt acacggtatc gattgccatc aaattatttg cagacgctgg
    16381 atctagtacg acttacgcga gtatgtttgc gatgtctacg ttgtcgctgc taccggtttt
    16441 tctgattttc ttattcttca ataaatatct tgtccagggg atcagtacaa gcggtctgaa
    16501 gggctgaata tgaaaaagcc aatagaagag atgtttcttt acaagctcaa ctactatgtc
    16561 tgtcggattt ttttaaccag tcttatcagt aatgctcttt tcgctttagt tctaggatgt
    16621 ttgttcactt taggattagt gctgtctgct cgtgttgtct atctgattta ttttttgatg
    16681 atgtatcctt cttattatct atctgtccat tacttggcag aaaaaaaggt atgttggagg
    16741 aaaggaaaaa tcaaacggat gtgtttcatc attacgttgt ttcagctgtt tgtcattatt
    16801 tttgcagttg attggtattt attagtggga aagattggag cttggtatct gattcctttt
    16861 ctattgtgtc tgttgctttt tgtatcccat agttttttta gtacgctaat tgatatctgc
    16921 aaagaagata aagcagatag tcttgtttat ttgatcaaaa ggaatatctg gctgttgtca
    16981 aaaaacgtca aggggtttct gtggtattta tgccttttgt atggactgtt ctggtgtata
    17041 cagcatgatt ttttactcac tgcattactg tatccagggc tgccatttgt cacagtattt
    17101 tgcttaaaag aaaaggagaa tgactttaaa tgaagaaaaa atatgtacaa gtcggacttg
    17161 gtgggagagc gcgttttttt tatgaggcaa ttgcctctac gtatcatcaa acttgtgaac
    17221 tagtcggttt ttgtgatgta tctcaaacaa ggatggatta tgcaaatcgg atacttgtga
    17281 acaagtatgg acagaaaaaa gtaaagacat gtatgccatc acaatttgag caactactgg
    17341 atgacgtacg gccggctgaa gtcattatta cgtcagtaga tcgaacgcat catgattata
    17401 tcattcgtgc aatgaaaaaa ggatatgatg ttatttgcga aaaacctctg actatcgatg
    17461 aggaaaaagc tcaagaaata ataacggtcc aaaaacagac gggaagaagc ctgcgagtca
    17521 cttttaatta tcgttatgca ccgtatcaca cgaagataaa ggaactgata gaaagtgatg
    17581 tgattggtga tgtgttttct atccacttcg aatggctgtt aaatacgcaa cacggggcag
    17641 attatttcag aagatggcat cgaaataagc acaatagcgg cgggcttctt gttcataaat
    17701 ctacccatca ttttgatcta gtgaattttt ggttgaacag ccgtccccaa aaggtatttg
    17761 cattcggtgg attaaacttt tatgggatgc ataatgcgga gaaacgcgga gtagaaatat
    17821 tttacagtcg atgctatgga agcgaactag ctaaagctga tccatttgct atagacctgt
    17881 cagccaatga ggaattgcga gaaatgtatt tagaagcaga aaaagacagt ggatatattc
    17941 gtgaccgcag tgtattttcc gatgatatct ctattgaaga tacactaggc gtaacggtca
    18001 aatatgaaac tggtgcgatt ttgacgtatt cgctaaacgc gtatatgccg tgggaaggat
    18061 tcaatgtttc tttcaatggc agcaaaggac ggatcgaaat gaaagtgatc gaaaagtctt
    18121 acatcaatgc aggtggagat aaaaaggatg aaggagcagc cgttcttcag tccatccatg
    18181 tctatccgat gttcggtgag ccatatgagg taatcgtcga acaagaagcg ggcggacatg
    18241 gcggaggaga tccgcgttta ttagatgatc tatttggtga agaaaaagaa gaagatccgt
    18301 ggaatcgggc agcaactcac gtagatggta ttttgtcgat tttgacagga atcgcagcaa
    18361 atcattctat tgcttcagga aaagcagtag tgattgacga gcttgtcagc ttaaaagaat
    18421 aagaatagat ttacggaaat tacttcccgt agtttataaa atcttgcctt attgccgata
    18481 ggctgtcttt tgaacactat ttattcggaa aaaggggcta tgacatgctt tttgtcatgc
    18541 cttcttttta tgtgggctgc ttttttagat aggagaaaat aaaaataact atttaaaccc
    18601 gaacaaaaag gaataatgca ttaaaaatca ttagatttta caaaaaaata agtaaaccac
    18661 gttgtcagtt tcagaaagta gtgttagact gttttcaata tttgaaacaa cattttttat
    18721 tcaaatatgg caaactgcct tcacgtgcaa aacagttgca agaaaatgaa tttacactat
    18781 tattagtttt acatacctac ttatatatcg tcataatatg gatgacagtt tctagccagt
    18841 accgtaaatg ctggactata agtaaaagat tggctatttc acccttcttt tcttatgata
    18901 aagtggaggg tgtttttctt taacagaaac atagtaggtt tttgcacaaa agcggttatt
    18961 tcggtattaa taaatgataa aggagcaaat aaagtgaaag aattagttga acgtattcaa
    19021 aaagacggac gtatattagg cgagggcgta ttaaaagtcg acagcttcgt cactcaccaa
    19081 gtagaccctg tattgatgga acaaatggga aaacggtttg cagaagtatt taaagaacaa
    19141 ggaatcacga aagttgtgac cattgaagct tctgggatcg caccagcttt atttgctgca
    19201 agagaattag atgttccaat gatcttcgct agaaaagcaa aaagtttgac gatggatgaa
    19261 gaattattga cagcttctgt ttattctttt acgaaacaag tgacaagtac gatttctatt
    19321 tctcgtaaat ttttatcttc agaagacaaa gtattgatta tcgacgattt cttggcaaac
    19381 ggacaagcgg caaaaggatt gatcgaatta tgccagcaag ctggagcgca agtagaagga
    19441 atcgggatcg tcatcgaaaa gtctttccaa gatggacgtc agttacttga agaaatggga
    19501 ttgagagtcg tttctcttgc gcgtattgct tccttgacga atggacaagt tgagtttctt
    19561 gaggaggacg cataatcgtg gaaaaagaaa cacaaaatgg aaaagctgcg gttttagggc
    19621 tgcagcatct gctagcgatg tatgcaggag cagtagcggt gcctcttttg atcggtacag
    19681 gactaggctt taatcaagaa cagatgactt atttgatttc aattgatatc tttatgtgtg
    19741 gattagcgac attattgcaa ttgacagtta accgattttt cggaattggc ttgcctgtcg
    19801 ttttaggatg tgcgatccaa gcagtagctc cactgatctt gatcggaacc aatgaaggag
    19861 taggagctat ctacggatct attatcgctt ctgggatctt tgttgtgtta gtttctggtg
    19921 tcttttctaa aattaaaaaa ctattccctc ctatagtaac aggaacggtt atcaccgtta
    19981 ttggtttgac tttgattcct gtagcaatcg agaaaatggg tggaggtaat gcaacagcag
    20041 ctgattttgg tgacaaaaca aatctgctac ttgcatttgt gacgattctc ctaattgtag
    20101 gcgtgcaaat gctggcaaaa gggttcattc gttcaatcgc ggtattgatt ggtttagtcg
    20161 gaggaagcat cttagctgct ttcatgggaa tgattgatct gagcgcgatt ggagatgcgc
    20221 cgttgttcca tgttccacaa cccttttatt ttggtaaacc aactttcgac gtatggtcga
    20281 ttttactaat gatcatcatt tccatggtca gcatggtaga atcaacaggt gtatattttg
    20341 cacttggtga cattactggg aaaaatgttg gagaagaaga attgaaaaag ggatatcgtg
    20401 cagaaggact tgccgttatc ttaggcggta ttttcaatac attcccttat actggctttt
    20461 ctcaaaatgt cggattggtt caactttcgg gaatcaaaac aagaaaaccc atctatttct
    20521 ctgcattctt cttgattgtt ttaggattat tccctaaaat cggtgcgtta gcacaaatca
    20581 tccctgagcc ggtacttggt ggaggaatgt tagtcatgtt cgggatggtg gcagtccaag
    20641 gaatccgtat gctgttggaa gttgatttca gcaatgataa aaatctattg attgttgctg
    20701 tttctgttgg atttgggctg ggtttcaatg ttacgccgac attattcagt caaatgccgc
    20761 aaacattgca aatgttcact ggaaatggca tcgtaatgag tagcattacg gctatcatat
    20821 tgaatttgat ctttaatgga ttgaaaaaag atgaagaaat attggaagaa gccttcaaga
    20881 agtaatagag caaaagaaag gttgtgaaat cagcgttttg acctgattgt tagagaaaca
    20941 aacggaaaaa tagttcctcg tattttgccg tttgtttgag ctaataccga gggtcagctg
    21001 attgaacacc gttgaaggaa gaggtcgtga gcctgccgtt catctccgag tcacaaggaa
    21061 caatttcaaa aaaaagcttc tcatgtttgt tgaatattgt tccttgtgac cgaggagttg
    21121 gcaggagaac accgtttatc cataaaaagg aatgtgacct aacttttgtc acattccttt
    21181 tttttatctt taataaacac gaacaataaa atgtttttct ttgttaacat tcgaaatttc
    21241 tttgacatca aaaaaagtga ttgttaaaat atgaatgtag aaaaactggg aggaaaaaca
    21301 atgacagcaa aaatctctgt gattatgggg agtacttcag attgggaaac aatgaaagaa
    21361 gcatgtcaaa tattggatga attcggtgtg tcttatgaaa aaaaggtcgt ttctgctcat
    21421 cgaaccccag atttgatgtt tgaatatgca caaaacgctc gaaaaaaagg aatcaaaatc
    21481 attattgcag gagcaggggg agccgcgcat ctgccgggta tggtcgcatc aaaaacaact
    21541 ttgccggtta tcggtgtacc ggtccaatca cgaacattaa atggtttgga ttcgcttctt
    21601 tcgattgtcc aaatgcctgg aggagtacct gtagctacta cagcaatcgg aaaagcggga
    21661 gcaattaatg ctggactact tgcgatacag atgctttcca tgtatgattt agaattggag
    21721 gctaaattgg ctgaaagacg ttcaatgttg gctaaaactg ttatagaaag tagtgatcaa
    21781 cttggttaaa cctttgttgc ctggttcaac gatcgggatc gtcggtggcg gtcaattagg
    21841 tcgtatgatg gcgattagtg caaaagaaat gggctttaaa gtaggtgtgc tggatcctgt
    21901 gagcgattgt ccagccgcac aagttgcaga ttggcacatt gaaagtgtct atgatgacac
    21961 ctttgcgctg aaagagcttg ccagaagaac agatgtcatt acctatgaat tcgaaaacgt
    22021 cagtgtagag gcgttaaatg cgattttacc catgtcattt attcctcaag ggacagactt
    22081 gcttgcgatt acgcaagacc gcctgttaga aaaatctttt ttggaaacga ataacatcgt
    22141 gattgctcct tatgcaacga tcgtcagtcc gacggatatc caagatgcga ttgacgggat
    22201 cggctatcct tgtgttttga aaaccactcg aggcggctat gatggcaagg ggcagtatgt
    22261 tttgaaaagt cgggcggatc tagctcctgc catggacctt ttaagagaag gaacctgtgt
    22321 tttagaagca tggatcccgt ttgaaaaaga gatttcgatc atggtggcag gaaatggtca
    22381 aggagatttc acgacttttc cggtcgtgga aaacatccac cacaacaata ttcttcatga
    22441 aacgattgct ccagccgcga ttgatcagga tgtgatcgag gaggctgagc gtattgcccg
    22501 tgtgattgca gaagcagtga gcctttcagg tgttttaggg gtagaaatgt ttttaacaaa
    22561 aacaggcggg ctatatgtga atgaattagc tcctcgtcct cacaattctg gacattattc
    22621 tattgaagct tgttctatga gtcagttcga tgcccatatt cgaggtattt gtggttggcc
    22681 attaggagaa aaagtacgtt tgataagcaa tgcagtaatg gtcaatgttt tgggagaaca
    22741 actgctggaa agctatcgct tgattgagaa taagccagac tggcaattcc atttctatgg
    22801 aaaaaaacaa gcaaaaaaag gtcgcaagat gggacatatc actatcttga cagaagacat
    22861 ccagcaaacg ctggaagaaa tcaaacaaac gaatatttgg gattagagga gaaaaaacat
    22921 gttagaacgt tatacacgcc ctgaaatggg gaatatctgg acggaagaga acaaataccg
    22981 tgcgtggctc gaagtcgaga ttttagcaga tgaagcttgg gcagaacttg gtgaaatccc
    23041 gcaagaagat gtgaaaaaaa ttcgtgagca tgcatcattt gatatcgatc ggatcttgga
    23101 aatcgaaaaa ttaacacgcc atgatgtcgt tgcgtttaca cgagcggttt ctgaaacatt
    23161 gggagaagaa agaaaatggg tccattatgg tctaacaagt acggatgtcg tagatactgc
    23221 ttatggctat ctcatcaagc aagcaaatga tattttacgg gaagacttga aacgttttac
    23281 ggaaatcatt ggcgaaaaag caaaagaaca caaatataca gtgatgatgg gtcggacaca
    23341 cggtgtccat gctgaaccaa ctacttttgg attgaaactt gccacatggt attcagaaat
    23401 gaaacggaac atcgaacgat ttgaacatgc ggcaaaagga gtagaagcag gaaaaatctc
    23461 aggagcagtg ggaacgttcg caaatatccc gccatttatt gaagagtatg tatgtaaaca
    23521 attggggatc cgtccacaag aaatctctac tcaagttctc cctcgggatc tacatgctga
    23581 atatttctca gcgatggcgc ttattgctac aagtattgaa cgttttgcaa cagagatacg
    23641 cggattgcaa aaatccgaaa cacgtgaagt agaagaattt tttgcgaaag gtcaaaaagg
    23701 ttcttctgct atgccgcaca aaaggaatcc gatcggttca gaaaatatgg ctggtctagc
    23761 cagagtggtg cgcggacaca tggtcactgc ctatgaaaat gtcacattat ggcatgaaag
    23821 agatatttct cattcttcag cagaacgaat catcttgcct gataccacga ttttattgaa
    23881 ttacatgtta aatcgttttg gcaatatcgt taaaaatcta acggtctttc ctgaaaacat
    23941 gaagcggaat atgtctgcaa catttggttt gatttatagc cagcgcgtta tgctgaaatt
    24001 gatcgataag ggaatgacaa gagaagaagc ttatgatctt gttcagccaa aaactgcgta
    24061 cgcttgggac aaccaagtgc agttccgccc gctgttagaa gaagatccaa ccatcacatc
    24121 ggtattatct aaagaagaaa tagacgatgc ctttgattat catcatcatt tgaaaaacgt
    24181 tgacgtgata ttcaaacgag taggtttgga ataaagaaga gtgagttgca aaattcaatt
    24241 aaaatagaat agcaaaaata atcgagtaga ggggaaagcc aactgacctt ccgcccctct
    24301 cacaccaccg tacgtacgga cccgtatacg gcggttcaat aagttgagtg tacgaactgg
    24361 tacttcaagg agatgtcctc atatccttgg cgggccagtt ctttgtctgt taatgatcga
    24421 tgaagaatat gacttttgga gactgaccaa ataccttttc ttgtatttga ccattcatac
    24481 gctttcgctt tatcgatccc taaacgaatc agattttttc ttttggttct tggattcttc
    24541 cattgtttcc aaatatattg tctgattctt cgcttcaacc aaccgtttaa ctccctcatg
    24601 aattctttca tctcaccaat tccatagtag ttgatccaac cagtcattag ttgcttgatt
    24661 tcttttaaaa taagttggat acttcttcca cggtttcttt tagtgagttg tttgagcttg
    24721 cttttcacac gctgttttgc ttttgcgtga gggcgaattt taataccttt ctttgttggc
    24781 agaatgcaga atccaagaaa ctttcgtttc aatggacttc ctaccgcact cttttctcga
    24841 tttaccgtca actttagttg ttcttcgaga aattgaatgg atttcttcat cacacgctgt
    24901 cctgctcgtt tgcttctaac atagatattg cagtcatcgg cgtatcgaac aaatttatgt
    24961 cctagatttt ctagcacttg atcaaattcg ttcaggtaga tgttacttaa caggggagag
    25021 agattgcctc cttggggcgt tccttcttca gttgttgtga tgagtccatt ttccattaca
    25081 ccactcatta agtattgacg gatcagtttt aggacttgtt tgtcctttac tttccgctca
    25141 atgaaataca tcagcttatc gtgatttacg gtgtcaaagt aggctttcat atcaatgtcc
    25201 accacatatc ggtaaccttg ttcataataa gattttgctt tcttcactgc gtcatgtgcg
    25261 ctgcgatttg ggcgaaaccc ataactatta tctgagaatt ctggttcaaa tagcggttgt
    25321 aacacttgat tgattgcctg ttgaagcata cgatcaataa ccgtgggaat tcctagtttt
    25381 cttacaccgc cgtttggttt cggtatttct actcgcaaaa caggctgagg tttatagttc
    25441 ccttggcgta aattggatag taattcctcg cggtgctctt tcaagtaagg aagcagttga
    25501 tcgacggtca tcccatctgc accagccgcc cctttatttc tgactacttg aagatacgct
    25561 tgattgagat tattccgatc tagaattctc ccaaacagat tttctacacc atcttgtttc
    25621 ctctgttcac cgcaagaagt gctgcgcact tcatcatacc cttcgtgttc cacactagct
    25681 ctttgatgat agccaagttt tcttgttttc tgcggtcgtc gcatcttctc acacctccta
    25741 aattattcaa gattcttatt gttcagtcct tcgtaacggt cagtgtcgtt actactatga
    25801 cctcggctga cttctcatga ttcaccatca tgtcgccatg atcgttgtgc tggtttgttt
    25861 tcattcaacg cccacaacac cctcatgaga tctcccccgg taagagtgaa aactttcctc
    25921 ccatgtaact gctagattta ctgtataggt ttcgggcagt attggacttt gtcttgtgat
    25981 gaagacttat ccgacctaat tcagccttgt atctagtttc tgttcgtcag ttcaggagtt
    26041 tgcgtccgac ttccttcagc cacaacctca cgattgccgc cttgtctttc gctaacagtt
    26101 cctactgcca agcctgtagt ggactttcac caccaagttt tcacccatgc agggcgcaca
    26161 ccaaaaaaga agcagatccg ttagcggttc tgcttctttt agtttattat attttcttat
    26221 caataatagg aacctgattt taaaagcggc tacctcttta ccgtgcctct ttacatacaa
    26281 aaaatagagg aattaagcgt aaatggcttg gctattataa ctaaaatgct ggttatggag
    26341 atgttgcagc aagttttcga gaaaagcgta ttccatctct tgtccattga ataagatctg
    26401 gatacgataa tgatttttga aacgcttctg ttcatgaatc tgactgattg aaagttcgcc
    26461 tttgtgttct gtctgataaa gaaaagtcct tttacggcat tcagcacagc gcttggttgc
    26521 tcggcggatt tttcggaatg tataaaaact agtatcttta ttgcataaat aaacgtcttt
    26581 gatcgacagc aaatcattat atagacagga acgttcttca gctgttaatt ctgataaaaa
    26641 aagctgacct tgttttattg catcttccat cggcaagtgc ctcctcgaac ccattatcca
    26701 aatttttagt taattctaat ataccatcat taagtataaa tgtaaacgct tgttgatggt
    26761 ataagatttt cgtttctgat aaaacacgaa cattaaaaga atctaatgcc ttaaatgtac
    26821 atatttttgt tgatttataa aaagatgatt gctaaaattt aaagtgaaaa aacgaacaaa
    26881 aaacgatgta tttgctttta atgtaaataa aaaggagaga cgtacatgga gaagaaagaa
    26941 cttttgtatg aaggaaaagc caaaaaaata tatcttactt ctgatgagaa cttgatttgg
    27001 atagaatatt tagatcaagc aactgcgttg aatggcgcga ggaaagacca gataagtgga
    27061 aaaggagaat tgaataatca aatcacaagt gcaattttcc gttatctgac tcaaagagga
    27121 ataaaaaatc attttattga acaattgtct aaaaccgaac aattagcaaa aaaagtacaa
    27181 attatccctc tggaagtggt tatccgaaat attgcagcag gaagtttctc aaaacgtcta
    27241 ggtgttcccg aaggtaaaga attcatcaaa ccaatcattg aattctacta taaggatgac
    27301 cagttggatg atccatttat caatgaagag catatctatt tcttacaact tgcaaagccg
    27361 gaagaaatca gtgagctgaa agcccaagcg ttggctatta atgaaatttt gaccgaatta
    27421 tttgctaagg tcggtttggt tttagtagat ttcaagctag aatttggccg gtcgaatgga
    27481 caaattttgc ttgcggatga agtaacaccg gatacttgcc gattatggga tgaacgtacg
    27541 aatgaacata tggacaaaga cgtttaccgc agagatctag gtgatttgat cccagtctat
    27601 caagaagtat ataaccgtct atcggaacta actgaagaaa aggagcgagt atgatgtatt
    27661 tcgtaaaagt atatgtaacc tataaagatt cagtgttaga tcctcaaggg gaggcagtaa
    27721 aaaaagcagt ccatcgtatg ggatatgaaa caatcgaaga tatccgaata ggaaaatact
    27781 ttgagataca acttgctgat gcagaagaac caatcgatac agtgattgaa acgatttgtg
    27841 acaagctgct tgcaaatgta aatatggaaa cataccgata tgaaatcaaa aaaatggagg
    27901 aagtataaca tgaaatttgc ggtcatcgtt tttccaggtt caaattgtga cgcagatatg
    27961 ttatgggcag ttcgcgagat catgggcgct gatgccgaat ttgtacggca tgatgagtcc
    28021 tctttagaag gatttgatgg ggttttactg ccgggaggat tctcctatgg tgactatttg
    28081 agatgcggtg cgattgctcg gttttctaca atcatggaag aagtgattcg ttttgctgaa
    28141 gaagggaaac cagtattcgg tacatgcaat ggattccaga tattgacaga agcaggactt
    28201 ttgccaggtg tactgagacg aaatgagtct ttgcatttta tttgcaaaac tgtaccattg
    28261 aaagtcaacc ccaagacggc ctttacttca gagtatgaag ccgacgaaat aatctatctt
    28321 ccagttgctc atggggaagg aaattatttc tgtgacgaag aaacacttca agaactaaaa
    28381 aaaaataatc agattgcctt tacttataat gacaacatca acggcagcgt ggaaaacatt
    28441 gcagggatta cgaacaaagc agggaatgtg ttaggaatga tgcctcatcc agaacgtgca
    28501 gtagaagact tgctaggatc agaagatggg aaacggttct ttgcttccat tttaaaaaac
    28561 ttcggaaagg tgaccgtata gatgaaaaca ttgaaagaac cgacagctga agagatcaag
    28621 aaaaaaagaa tctatgccga atggggattg actgatgaag aatatcgaat gatcgaagaa
    28681 gatatcttag gaagaatgcc taattatacg gaaactggac tgttttctgt tatgtggagc
    28741 gaacattgtt cctataaaaa ttctaaaccg gttctacgca aatttcctac tagtggacct
    28801 catgtgttgc aaggccctgg agaaggcgca ggcatcgtcg acatcggtga tggactagca
    28861 gttgtcttca aagcagaaag tcacaatcat ccttcagccg tggagcctta tgaaggagct
    28921 gcgacaggag ttggcggaat catcagagat attttcagca tgggggctcg tccaattgcg
    28981 ttgctagatt cattgaggtt cggcgaatta gataatccaa gaacgaaata tttactagaa
    29041 gaagtagttg caggtatcgg cggatacggc aattgtatcg gcataccgac tgtaggcggc
    29101 gaaattgcat ttgatccttg ttatgaagga aacccattag tcaatgcaat gtgcgtaggt
    29161 ttgattgaac acaaacatat ccagaaaggg caagccgctg gcgtcggtaa ttcgatcatg
    29221 tatgtaggtg caaaaacagg tcgcgacggt atccacggag caacttttgc ctcagaagaa
    29281 tttaatcaag aagaagaaca gcaacgttct gctgtacaag taggcgatcc ttttatggaa
    29341 aagctgctgc ttgaagcgtg tttggaatta atcttgcatc attcggattc tctaataggt
    29401 atacaggata tgggagcagc aggacttgtt tcatctagtg cggaaatggc ttcaaaagct
    29461 ggctcaggac ttatattgac attagatgaa gtcccacaaa gagaaactgg gatgacacct
    29521 tatgaaatga tgttatcgga atcacaagaa cggatgttga tttgtgttaa atcaggagag
    29581 gaagaaaaaa tccaagaact atttcagaag tatgatctag atgcagtcac tatcggtaaa
    29641 gtaacagacg acgggcaata tcggctatat catcaaggag aagaagtagc aaatctgcca
    29701 gtcgatgcat tagctgaaga tgcaccagtt tatcataaag aaatgaaaga accagctcga
    29761 atcgtagaat ttcagcagtt agctccttat cagccagtta tcgaagaacc tggacaagta
    29821 ttgcttgatc tgctgcagca accgacgatt gcttcaaaac gttcaatcta cgaaacttat
    29881 gattcacaag tacaaaccaa tacagttgtc cgtccaggaa gcgatgctgc tgtgatgagg
    29941 gttagaggga cgaataaagc gttagctatg accacagact gcaacgcgcg ctatctgtat
    30001 ttggatccaa aaatcggagg acaaatagca gtggcagaag ctgctagaaa tattattgct
    30061 agcggtggta agcccttggc gatcaccgac tgcctgaact atggttctcc tgataaacca
    30121 gaagtttttt gggaattatc gacttcagct gacggaattg ctgctgcgtg tgaaacgtta
    30181 ggaactcctg ttatttcagg aaatgtctct ttatataatg aaatggatgg tcaagcaatc
    30241 tatccaacac caatgattgg tatggtcgga ttgattgagg atcataaaca tatcactact
    30301 caggaattca aaaaatcagg ggatctaatc tatatattag gtaagacgtt tgcagatttt
    30361 gatggcagtg aattacaaaa gatgcagctt ggaagaatcg aaggtgtgat ccgaaacttt
    30421 gatctatcca ttgaaaagag aaaccaagag ttagtattga cagccatcca aaacggattg
    30481 attgaaagtg ctcatgactg ttcagaaggt ggcttggcaa ttgcactggc agaatcagct
    30541 ttcaaacatc agctagggat atctgtacag tttgaattgt cctctgctca attatttgca
    30601 gaaactcaat caagatttgt gttgacagtc gcaccggaaa ataagacacg attcgaagaa
    30661 atgatgggag atgctgctgt tttagcaggt aaggtgacgg atgaagcgat aatcgaaatt
    30721 tcagcaactg acggtcagat caaaatagaa actgcagtag caagaaagtg ctgggaggat
    30781 gcaatcgtat gtcttatgaa gtgaagagtt taaatgaaga atgcgggatc ttcggtgttt
    30841 ggggtcatcc agacgccgct agtgtggcat acttcgggct ccatagtctt cagcatcgag
    30901 gacaagaagg tgcaggtatc gtgtccaatg atcgaggaaa gcttaagggg catcgagatt
    30961 tggggctgct ttctgaggta ttcaaagatc aaagaaaatt gcagcagtta acaggagaag
    31021 ctgcaatcgg acatgtacgt tatgcaacag caggcaatgg aagtgtggac aatattcagc
    31081 cttttctatt caaatttcat gatcagtcga tcggcttagc gcataatggt aacttgatca
    31141 atgctcgttc ccttagaaaa gagttagagg aaaatggggc gatcttccat tctaactccg
    31201 atacggagat attgatgcat ttgatccgac gaagtgaaga aacagatttt ttaaataaat
    31261 taaaaagtgc tttgaatgaa gtcaaaggtg gctttgccta tttattaatg acagaaacgg
    31321 caatgattgc cgctttggac ccaaatggtt ttcgtccatt agcaatcgga caaatgaaaa
    31381 acggagcata cgtgattgcc tcggaaactt gtgcattaga agttattggg gcacgtttta
    31441 taagagatgt ccagcctggt gagatagtga tcatcaatga cgaaggaatc cagattgatt
    31501 gctttacgaa ggacacgcag ctttctattt gttcgatgga atatatctat tttgccagac
    31561 cagattcaaa catcgcaggg atcaatgtgc atactgcacg gaaaaatatg ggacggaatt
    31621 tagcgaaaga atcgccagta aaagcagata tggtcgttgg cgtacctaat tcttctttgt
    31681 cagccgcaag cggttatgcg gaagctagtg gaatccctta tgaaatcgga ttagtaaaaa
    31741 atcaatacat tgcccgaaca tttatccagc caacgcctga gctaagagag caaggtgttc
    31801 gaatgaaatt atctgctgta cgaggagtag tggaaggtaa aaaggtgatt atggtcgatg
    31861 attcaattgt tcggggtacg acaagcagac ggatcgtcca tcttttgaaa gaagcagggg
    31921 caaaagaagt ccatgtgagg attgcttctc ctcctttgaa atatccatgt ttttacggga
    31981 ttgatattca aacgcgtaaa gaactcattg cggcaaatca cacgattgat gaaatcaaag
    32041 aatgtatcgg tgcagattct ttaggttttt taagtgaaga gggtctgatc gaatcgatcg
    32101 gtctggaaaa agatgctccg tattcaggat tgtgtatggc ttatttcaac ggagattatc
    32161 cgacgccgtt atatgactat gaagaaaaat atcaggaatc actaaaagaa aaagtatcgt
    32221 tcttttaaaa gcagaccaag aagggagtat atgaattcaa tggcaaatgc atacgcaaaa
    32281 gctggcgtag atgtcgaagc tggatatgaa gtagtagaac ggatcaagaa gcatgtcaaa
    32341 aaaacggaac gtttaggtat gatgggcgct ataggaggat tcggcggttg ttttgattta
    32401 tcggtctttc aattaaaaga gccagtcctt gtctcgggga ccgatggcgt ggggacgaaa
    32461 ttagcagtgg caatcgaagc agacaaacac gatacaatcg ggatcgactg cgtagcgatg
    32521 tgtgtcaatg atatcttagc acaaggcgca gagccgttat atttcttaga ctacttagca
    32581 acggggaaaa atgatccgtt acgtttggaa aatgtagtaa aaggtgtagc agatggatgt
    32641 gttcaaggaa atatggcgct gattggcgga gaaacagctg aaatgcctgg tatgtactca
    32701 ggtaatgatt atgatctagc cggatttgct gtagggatag ctgaaaaatc tcaattattg
    32761 acaggagaaa cgatcaaccc aggagatgtg ttgcttggaa tagcatctag cgggattcat
    32821 tcaaatgggt actctcttgt tcgcaaaatt ttctttgagc agcagcagtt ttctttatca
    32881 tcaaaactgc cagaattgaa aaaaacactt ggcgaagaat tgcttgagcc aacgaaaatc
    32941 tatgtttctt ccttgcttcc gctgatcaaa gaaaagaaaa taaaaggagc tgcacatatc
    33001 actggtggag ggtttgtaga aaatatcccg cgaatgttac cagaatctat ggctgcacaa
    33061 atcaaacttg gctcatggcc gattcttcca atattcggct gtttacaaaa atatggtgaa
    33121 attcctgaga tggagatgta tgaaatcttc aatatgggca tcggtatggt cctggcagtc
    33181 caagaatcga aagtaaaaga aatagtacac gaaattgagc aagctggcga aaaagtttat
    33241 gaaatcggga aagtgatcgc caaagaaaaa catcgtgtgg tgtttatagg agaagaacga
    33301 tgagaatcgc tgtttttgct tctggaaacg gaagcaactt tcaagcgcta gccgattatc
    33361 tatcgaaaaa aggattggaa tcttcgattg actggttgtt ttgtgatcag cctgaagcat
    33421 atgttttgaa acgtgcaact gcgttgagtg taccggcaga ttgtttttca cctaaagaat
    33481 ttgattcaaa aaaagagtat gaagaagcaa ttttgcataa attgaaagaa aaaaagatcg
    33541 atttgatcgt attagctgga tatatgcgaa tcattggacc ggtattgctg aaaaattatg
    33601 ataaaagaat catcaatatc catccgtctc ttttacctgc cttccctggt ttgcatggca
    33661 tacgtgatgc ctttgaagct ggagtaaaag aaacgggtgt cacaattcat tatatcgacc
    33721 aaggtgtaga tactggacca atcatccggc aggaaaaagt gagaattgaa caggaggaca
    33781 cgttcgattc tttagaagaa aaaatccata gagtagagca tcgaatctat ccagaagtga
    33841 ttagtgaaat tattgaaaat ggaggctatc tgaaatgaca agagcattga tcagtgtatc
    33901 agataaaact gggattgtag cattcgccca aggtttgatt gaacaaggag tagaaatcat
    33961 ttcaacagga ggaacaaagc atgcgttgga taaagctggg atcaaaacgc tttcgatcga
    34021 agaagtgaca gggtttcctg aaatgatgga tggccgtgtc aaaacacttc atcctaaaat
    34081 ccatggtggt cttttaggaa gacgcgatct ccctagccat atggaggcaa tggaaacgga
    34141 aaatatccaa ccaatcgact ttgtttgtgt caatttatat cctttcaaag aaacgattat
    34201 gaaaccagat gtcgaaatag cagaagctat tgaaaacatt gatatcggtg gtcctagtat
    34261 gctccgtagt gcagcaaaaa accatgaatt tgtcacctct gttgttgatc catctgacta
    34321 tgaagaagta ctttcagaat tacgtcagta tgggcatact tcactttctt tcagacaaaa
    34381 actagcggca aaagtctttc gtcatactgc ggcatatgat gcactgatcg ctcaatactt
    34441 aacggattgg gtggaagaaa aagaaccgga aaaattgaca cttacgtatg aacgaaaaca
    34501 aacgcttcgt tacggtgaaa atagccatca agccgctgcc ttttatcagt ccgctcttct
    34561 ggaaaaatat tcgatcgcag cagcaaaaca actccatggg aaagaacttt cttataataa
    34621 tatccgagat gcagatgctg cgctacggat catgaaggaa tatgacgagc caacggtagt
    34681 cgccttgaaa cacatgaatc cttgtggtat tgggacagca tctacgattt tagaagcgtg
    34741 ggaagcagcg tatgaagcag atcctgtttc aatctttggt gggatcatcg ttttgaatcg
    34801 agaagtagat ctgccaacag cagaacagat gcataagctg tttctagaaa tcatcattgc
    34861 cccttcttat acacaagaag ctttggaatt actgcaaaaa aagaaaaaca tccgattact
    34921 gacagtagac tttgcgcagg aagaaaatca aaatcgagaa gaaacggtct cagtcttagg
    34981 tggacttctt gtacaagatc aagatctggc aatagaaaat gaagaagagt ggaaagtcgt
    35041 gacaaaacgt aagccgactc cagcagaagc aaaagcatta gcgtttgctt ggagagctgt
    35101 caaacatgtg aaatctaatg cgatcgtact ggcaaacgaa cgtcagacag taggaatcgg
    35161 agccgggcag atgaatcgag tcggttcagt aaaaattgcg attgaacaag cgcaagagaa
    35221 aatggaaggt gcagttttag ctagcgatgc ttattttcca atggatgatt cggttgaata
    35281 tgcagccaaa catggtataa aagcaatcat tcagccagga ggaagcatca aagaccaaga
    35341 ttctattgat atggcgaata aatacgatct agcaatggtc tttactgatg ttcggcattt
    35401 tagacattag agaggagtcg gataaatgaa cattttggtg atcggtgcag gtggtcgtga
    35461 acatgcaata agtaaaaaac ttttagccag tccgaaggtg gatacggtgt attgtgcgcc
    35521 aggaaatccg gggatgacaa aagatggtat caattgtgtc gctatcagtg agcgagatca
    35581 ttcagcgtta atccattttg ttaagaaaga ggctattgat tggagtatcg ttggtcctga
    35641 agttcctttg ttaaatggga tcgtcgatga ttttatggcg gaaggattga aaatcttcgg
    35701 tccgacaaaa gcagcagctc tgatcgaagg ttcgaaaagt tttgctaaac aattaatgga
    35761 tacttatcaa atcccgacag ctaaatccag aagttttgaa tgttacgaaa aagcagcagc
    35821 gtatatcaaa gaaaatggtg cgccaatcgt agtgaaagcg gacggcttag cagctgggaa
    35881 aggtgtagtc gtggctacca cagtgaagga agcgctggat gcggcagaac aaatgttgaa
    35941 ccagcatcga tttggggata gtagcaaaaa aatcgtcgta gaagagtttt tggcaggaga
    36001 agaattctcc cttttggcgt ttgtccgtaa taccaaggtg tatccgatgg tcatttcgca
    36061 agatcataag cgggcatttg ataacgataa agggccaaat acaggcggaa tgggtgctta
    36121 ttcaccagta ccgcaaattt caaaaaagat gattgaaaaa gctgtggaag aagttttaaa
    36181 accagcggct ttgggaatga aagaactagg acgctctttc acgggtgttt tatatgcggg
    36241 tttgattgct acgaaggaag gaccaaaagt gatcgaattc aatgcgcgtt tcggtgatcc
    36301 tgaaacgcaa gtcgttcttt ctcggttgaa gagtgacttt gcgcaagtaa tcgatgattt
    36361 attagagaat cgtacagtag agttaaagtg gcagcaagaa ggatacaatg taggcgttgt
    36421 ggttgcagct gccggttacc ccgaagaata tgagacagga atggttctac cagattttct
    36481 ggaagaagag ctttctgttt actatgctgg agtttcctca aataacggca aactagttgg
    36541 agcaggagga cgtctttatt tagtagaagc atacggtgag acgatcaaag aagcacagaa
    36601 aaaaatttac accgcgttaa tggataaaac gacagatgga acattttatc gtacagatat
    36661 tggagaaaaa gctgccaata gcgaactgat cgtgaagtaa atcagctgct tccatttata
    36721 aaaaatacaa caaacataat cggaagcgcc gattttagtg aagccttttc ataaagagtg
    36781 tggtacactt ttgttgtgta tataaataag gaggagttca gatgaaaaaa attcaattag
    36841 gtacttctga tcagaaagca gctgcagtga tcttaggctg tatgcgtatc aacaatgcgg
    36901 aagatccagt aaaagtgatt gagacagctt atgaaaacgg cattgatttt tttgaccatg
    36961 cagatattta tggaaacggt gaatgtgaag aaatctttgc agatgctcta gcaaaaacat
    37021 caatcaaacg agaagatctt tttattcaaa caaaatgtgg aatcgttcca ggtgtgatgt
    37081 ttgatttttc taaaaaacat atcattgaat ctgtagaaaa aagtttgacc cgtctgaaaa
    37141 tggattatgt ggatgcttta cttcttcatc gtccagatac attggtagaa ccagaggaag
    37201 tagctgaagc gtttgatgaa ttggaacggt caggaaaagt tcgttatttt ggcgtcagca
    37261 atcaaaaacc aatgcaaatc gaattgctga aaaaatatgt tcgtcaacca ttagtagcta
    37321 atcagctgca atttggcttg aaacatactg gaatgatcga tcaagggatt catgtcaata
    37381 tgacagatga agcaagtatc gatcatgacg gtagtgtact tgattattcc cgattgcatg
    37441 atatgacgat ccaagcatgg tcaccatacc agtatggatt ttttgaaggt gtatttatcg
    37501 ggaacgaaaa attccctgaa ttaaaccaaa cattagaaga actagcagct aaatatcaaa
    37561 cgacaccaac tggcttggct tctgcttgga ttttacgcca tccagccaat atgcaagtga
    37621 tcgccggtac gatgaacgta gggcgaatca aggaaatcgc tcaagcttca gaaattaata
    37681 tgtctcggga agattggtac gaattgtacc gtgctgctgg aaacatttta ccttaaagat
    37741 tgtcataagc aggtcaaaag ggctataaat taaaaagaca gaataacttg aaagctgttt
    37801 tcagcttcga gatattctgt ctttttttat tgcaaatgga aagagtatca ttgtacggat
    37861 ttcgtttatt agttattttt gtttttaagg aaaagctgtg tccgatattc ttttggagaa
    37921 atcccttgtt ttttcttaaa taaataactg aaatagttag ggtcattata accaatttca
    37981 aaagcaatat ctgaaatacg atagtctgat tgctgcaata atttttttgc taattcgatt
    38041 ctttgttctg tcagataatc gatgaatgtt tggttaaacg attgagaaaa aatcgtactg
    38101 aaatgagagg gacttaatgc aacttgttga gcgacccaag ttaaggacat atctggatcg
    38161 gtaaaatttt ctttgataaa atccaatgca tggttcaaaa ttggctgata tttgttcctt
    38221 gaaggctgtg agggcagagc agttaagaaa gaaatgaaca tataaactgt cgaacggtaa
    38281 agcgagtcgt cggcgctgat tgctaagcgt tgactggtgg atgtgcaatg aaccatttct
    38341 tgcgggattt tcttttcttt caggcagaca tgctggagta gcttagtcaa gacaaataaa
    38401 cgatataatc gtgttcgagt tggtgtgcct tgtggtttcg tcaagtgttc gatgtactta
    38461 gatacttcgt ttttcgataa tgaagacaaa tcaagtgaga ggtcaaagta aaagacagaa
    38521 tcaactggaa gtttcgcttc ttgaatcaaa tcctcatagc tgataatttg ttctttaagg
    38581 gaactggcgg tttcaagtat catctgcgtg atctcaaaag atgcaggtaa ttcgctgatt
    38641 ctttctgcga caggaccaat ggcgacagaa aaattatttt tttgtccctt ttctaattca
    38701 tggaccaacg tttgggctac ctgataactg gtctcgatca cattttcttc aagagaatca
    38761 actattaaaa atttgatgaa tcgagaggaa acagcagaga agatcacttg ttgattctcc
    38821 ctaaataaaa acttcaaata atcactgaga tgagcgtaat cttcaaagtc tgtactgact
    38881 tggtttgctg ctaataatac ggtcattttt ttccctgcta aagagcgatt gaaagattca
    38941 gcaagtttca atgtttcact gatcgtaagt gagcctttga acaaaccgtt caagaaatga
    39001 ttttttttca attcgaaaac aagatcagaa gaagtgtgcg tttctttttg ctgcaaatct
    39061 aaagcagtta ctgctttttc tattgcttgt ttcaattcgc tacttttaat cggtttaagc
    39121 agataatcat ctgcctgtac ctggattgct cctttcatat aatcgaaatc gtcgaatcca
    39181 ctaataaata tgagacgagt ccaaggaagt agtttccttg cttcttttga aaaagtcaac
    39241 ccgtccatga aaggcatttg gatatcagtc agaatgatgt cgggctgtaa gtcgataatt
    39301 gaagacagtg ccatctcacc atctccagct tcgccgacat aagtgattgg ataataagaa
    39361 ccaaggacag ttatttgttc ccgcaagtta ttgcgaatga ggtattcgtc ttcgatgata
    39421 aaaactttat acatgtttgt ttcctccaat tgttttggga gatagaggga tcatcagtgt
    39481 gacagttgtt ccttctcggt atttgctgtc aatcgtgata ggtttttgat catttccgta
    39541 ataaagaagg agacgcttgt ttacgttgta aagtccgtag ccgatactga aatctgaatc
    39601 gatccctttg gctaactctt tacgtatttc tgccagtttt tctgcaggga tgccaatccc
    39661 gttgtctata actttgaatt ggatcatctc atcaattttg catgtggtaa tacgaataaa
    39721 tcctttgtga cggacgtact tcgttccatg gtatacagca ttttcaatca atggctgcaa
    39781 gatcattttt aaaatagaaa caggaaaaag tgtttctggt atatcgatct tatagtcaag
    39841 catatggccg tatcttattt ttaagatgac tagataatca ttgatatggc taatttcttt
    39901 ttcaagagga atccagtctt gtcctttgct taaagacgta cgaaaaaagc cggaaagtgc
    39961 atgggtcata gtcagagctt cttcaaagca gtcttgttcg atcaaagaaa taatggcatc
    40021 caaactgtta taaataaaat ggggagtaat ctgagcttgc aatacacgaa cttcactttg
    40081 tgctaaatgg tattgtttca aagcgttctc ccgtaaagac tggtttagat cttccgccat
    40141 tttattcatg ctagcggtaa gtgtttgtaa ttccagtgtt tccggcaggg ttaaacgaaa
    40201 gccaaggttc cctgaagaaa gttgttctga catctcgatc agctgattga tcggttcttg
    40261 gacctttctc tctaaaaagc gacgattctt tttcgcatag aaaaaaatgg tactaagaac
    40321 tccaagttcc actattgtta atagaatgag cgagcggaca agtgtcgtat tttttttgct
    40381 tgctaagtcg atctccacac gaacaaaatc ttgtaagata tctgacagca gttgagtgac
    40441 agaatctacc tgattgatga tctcttcatt ggtatccata aaatcttttg ccaagatatt
    40501 attgatcagc tcgttttgat aatcttccag tgtatcgatc gtacgtagcg atacatctaa
    40561 cgtactaatt tctttaagtg tatttgtatt atttttgatc tctcgaatat cattcctaag
    40621 ttcttctagg atattttcct cattgaactc atctacggtt acttggccag aaatcaagtc
    40681 ccacatactt tccaaaactt tttgatcaac cttcaaagca attgcatctg ctttttggat
    40741 atttgcgatc gtctgttgat aaatcaaaag ctgttgcgaa tataacagta tgctcagtag
    40801 caaagggata acagcaaata gaagcatggc tttgtttgct tgggcaaaaa tctgttttat
    40861 gcttaaattt tttgtcatga tacttctcca gtcaataatt tctggttggg atgttagcta
    40921 tattctgctg ggaaaagaca gtctcggaaa taaaaatatc tttaggtaat gtttttcctg
    40981 tttgaatatt tccaaaataa cgagtaacgg tattggctac ataccagccg acatcaggtt
    41041 tacactcgac tacacaattg acgattcctg agcgtagctt ctcgatcata tcttcttgtc
    41101 catcaatagt tacaatgatc aaatcttctc caggtttgat tgatgtttct tttatcgcag
    41161 ctaaagcacc gtgagtcatt tcatcactat ggctgtataa tacatcgatt tcggataaat
    41221 catttgtttc taaatatcgt ttcatctggt cttttccttt catccgaata aaatcaccga
    41281 caattcggtg aacaatagtc atcggaggtt tatggtcgat ggttccatct ttttttaggg
    41341 ttggtttacg attgattgat tccaaaaatc cttcggagcg tagcttggtc ggtgtggagt
    41401 tctctgaacc agcaagttct aggattctga tttcctgttt ctttgaattt gtgaagtgat
    41461 tgctgacaaa taaacccgcc cgatttcctt ctgctttgaa actggggcca atgtgggtga
    41521 cgaaaagctc gggatcattc gtttgaatat gtctgtcgac aagtatgaca gggatccctg
    41581 ctcgctttgc ttcttttaat acagagtccc acccggattc ttgcaaagga gtaaaaatga
    41641 tcatatccac tttataggca atgaacgtcc gtatatcttg gatttgccgt tcctgattca
    41701 tgtagccatt tcggtagaga acttggtaat cttctttttc aagcgcagtg ataattgatt
    41761 cagtatgctt tttccgccag ctactctccg ttcctgattg cgaaaaacca acgactagtg
    41821 ggtcaggtgc ttcctttgta ttaggtgtac accccatcat ttggtaagcg attacaacaa
    41881 gggctaaaaa aaataaaaca cgtttcactt taaatcactc catctggatt tgttagtact
    41941 atcttatcag ataaaaggga aaatcaaagt caaaaggaat caatcgaaaa aaatccaaga
    42001 aacttaaaaa aatccaagac aaaaaaagta cacctaaaaa atttaaagta aatcccataa
    42061 aaaaatcaat gttaacgctt tctttattag ctatactcgg tgtatcaatt gaaatggggg
    42121 ataaaaaatg aaaaacaaat ttagaaagat tgttgggact atcgctattt tgaccgcaag
    42181 cattctatta agtgcgtgtg gcaattcagg atctgcagat gatagtacgg ggtatgtagg
    42241 aatcgctatg ccgaccaaat cagcagaaag atggatcgct gatgggaaca acatggtctc
    42301 ggaattagaa aaactgggtt ataaaacaga tcttcaatat ggagaagata aagtagaaaa
    42361 tcaagtagca caaatagaaa atatgattac aaaaggggta gatacacttg tgattgcttc
    42421 tatcgatggt tcggctttaa ctgatgtgtt agctaaagca aaagaagcag atatcaaggt
    42481 gatcgcctat gatcgtttac tgatgaattc agaaaatgtc gattattacg cgacttttga
    42541 taattttgga gtaggtgtat cgcaagcagc ttatattgaa gagcacttag gattgaaaga
    42601 aggaaaagga ccattcacga ttgaattatt tggtggctcg cctgacgaca acaacgcact
    42661 aatcaattac aacggagtga tgtctgtttt acaaccatat atggacaacg gtcagttggt
    42721 cgtgccatct ggacagacga gtttcagtca aatcgctacg cttcgctggg atggttctac
    42781 ggcgcaagca aggatggata atctgttaag cgcaaattat actgaccaaa cattggatgc
    42841 tgttttgtcg ccatatgatc caataagttt aggaatcatt tcgtcattaa aaggcgtggg
    42901 gtatgggagt gaaagtaaac ctttacctgt gattactgga caagatgcga cagttgctgg
    42961 cgttaaatcg atcattgccg gggaacaaac acaaacgatc tttaaagaca cacgtatctt
    43021 agcaaaaaat acgattgaaa tgatcaaagc aatcagtgat ggagaagagg ttccggtcaa
    43081 tgatactgaa acttatgata atggggtgaa aactgtccct acgtatttag caaatacagt
    43141 atctgtcgat aaagataatt atcaagcaga gctgatcgac accgattatt ataaagaatc
    43201 cgatctgaaa aattaagagg aaccaaacaa ggaactaaag agatctaagt cagagagagg
    43261 ataagaatta tggcggattg tattttaaaa atggcagata tcaccaaaaa attttctgga
    43321 atccgagcgt tagattgcgt gaatctgatg attgaacgtg gggaaatcca tgcattgtgc
    43381 ggagaaaacg gagcgggaaa atcaacattg atgaatgtct tgagcggctt gtatccatat
    43441 ggctcctatg acggggaaat cttttatgat ggaaagctgt gtcaatttaa agatttgaaa
    43501 gatagtgaag aaaaaggcat cgtcatcatt catcaagaat tagcactaag tccttatctt
    43561 tcaataaaag agaatatttt tctcggaaat gaacaagcag aaagaggcgt gattgattgg
    43621 gaactgacag aaaagaaaac atatgaactg ctgaataaag tcggtttgtc tatcgacccg
    43681 aatcttctag tatcccagat tggcgtaggg caacagcaac tagttgaaat agctaaagca
    43741 ttatcaaaat ccgtccgtct gttgattttg gatgagccta ccgctgcatt gaatgaagaa
    43801 gaaagcgcga atttgctgag attgatccga gagttgaaag agcaaggtgt aacctccatc
    43861 attatttcac ataagctgaa tgaaatcgtg gatatcgcag atcgaatcac cattttacgg
    43921 gatggacaga cgattgagac actagaaaat gaaatgatca gcgaagagca tattattcgc
    43981 ggaatggtgg gcagagattt agttgatcgt tatcctgaaa gaaaaccgga tattggagaa
    44041 gtttatttta aagtagaaga ctggacggtc tatcaccctc ttgatcacga gcgaatcata
    44101 aacgaccaca tcaacttgca tttgaaaaaa ggagagattg taggaatagc tggactgatg
    44161 ggagcgggca gaactgaatt cgctatgagt ctatttggac attcttatgg aagcaagata
    44221 tccggacgta tattaaagga aggggcagag atatcagtta agaccgttcc ttcagccatt
    44281 gcaaacggac tcgcttatgt ctcggaggac cgaaaatctt taggactgaa tctgctgatg
    44341 gatattcggg aaaacgtgac gctgagcagt ttggataaaa taagtcaaaa aggagtatta
    44401 gataaagaaa aagaagtaac tgaggcagaa aatttccgga aaaagatgcg tataaaaaca
    44461 aactccatcc atcaaattgt cagtagtctt agtggtggga atcaacaaaa agtcgtttta
    44521 tccaagtggc tgatgacaca acccgatatt ctttttttgg atgagccaac ccgtgggata
    44581 gatgttgggg caaaatatga gatctacacg attatcgaag aaatggcagc aaatggcaaa
    44641 gctgtctgtc ttatctcttc tgaacttcct gaaatattag ggatgtgtga tcgaatctat
    44701 acgatgaacg aaggacgtat tacaggagaa gtctcgcgag aagatgcaga tcaggaagtc
    44761 ttgatgaaat taatgacgaa agaagaggtg ggttaagttg gaacaggcaa aaaatcttac
    44821 ggataaaaaa gagaaaaaac taaatttgaa aagtagagca gctgatcttt ttggtcgcta
    44881 cagcatggtg atcattttag cgggactact tattgcgttt caattgatga cggatggtat
    44941 tttctggcgt ccattgaata taactaacct tgttctgcaa aatagccata tattagtact
    45001 agctgcaggg atgttattag ttgtgctctt aggtcatgtg gatttgtcgg tagggtcagt
    45061 gatggcgttt gttggtgcaa ttgcgggcat gatgatggtc aatcgccaaa tgaacccgtg
    45121 gatgacagtt atcgcatgtc ttgcagtagg cgggctgatc ggcgcatggc aaggtttttg
    45181 ggtagcttat gcagggatac cggcgtttat cgtgacttta gcaggattgc tgatgtttcg
    45241 tggactgaca caagttgttc taggaggcca atctctagca ccttttccag ctgttttcca
    45301 aaaaatgtct acgggttatt taccagactt aagcgaagga agcagccttc acttcttgac
    45361 attgatttta ggaatgatca tcacgatcgt gttagttgtt ggtcaatggc gaacaagaaa
    45421 tcgtcggaaa aatcatttat ttgaagtgga atctccaaca gctttcttgg taaaggcggt
    45481 atttacagca gtcgttgtac taggaataac ttatatcttt gcctcttatc aagggtatcc
    45541 gattattttg atcattcttg gtttgatcgt tgcagcatat gggtttttga caaataaaac
    45601 agtagcaggt cgacagattt atgcgacggg cggaaatcga aaagcggctg aactatcagg
    45661 gatcaaaaca aagcgaatca cgttctgggt attcgtcaac atgggagtca tggcagcttt
    45721 agctggatta gttttagctg ctcgattgaa tgcggcaaca cctcaagcag gtacatcgat
    45781 ggaactggat gcaatggcgg cagtatattt tggtggtgct tcgacttccg gcggcattgg
    45841 aacaatcatg ggtgcgattg tcggtggctt ggtcatgggt gtattgaaca atggcatgtc
    45901 gattttaggc gtcggggtag actggcagca ggcaatcaaa ggattgatct tgcttttagc
    45961 cgttgtgcta gacttgtata ataagaaaaa acgaacaacg taggagaacg ccggttattc
    46021 agaaaaaaga ctgtgacaag acatttgtca cagtcttttt ttcgctaaaa gcgaacattc
    46081 attgtttcgt ttgtatagac taaaaataat atatgttttt ttaccattcg tataaattct
    46141 ctttttgctc ttgatttttt tgcttaattg agttaaatta catagggcgc taaaaaaagc
    46201 cttgattaaa ttaataatgt tcgtgttttg ctggatgtga acatcaggag gataatgtaa
    46261 tgaaagtatt tgattacgaa gatattcaat taattcctaa taaatgtatc gtaaatagcc
    46321 gttctgaatg tgatacaacg gtcacattag gtaaacatac attcaaaatg ccagtagtgc
    46381 ctgccaacat gcagacgatt attgatgaaa caatcgcaga attcttagcg gaaaatggtt
    46441 atttctatat catgcatcgg tttgatgaag cagctcgaat tccgtttatc aaaaaaatga
    46501 aaaagcgtgg attgattacc tcgatcagtg ttggcgtcaa gaaagaggaa tattccttta
    46561 tagagaagtt ggcagaagaa tcgctaaatc ctgattatat cactatcgac atcgcgcatg
    46621 gacatgctaa ctcagttatt gatatgattc agcatattaa aaaatatttg cctgaaactt
    46681 ttgtgattgc cggtaatgtt ggtacaccgg aagccgtccg tgaattggaa aatgcgggcg
    46741 cagatgcaac aaaagtcggg attggtccag gaaaagtatg tattacaaaa atcaagacag
    46801 gctttgggac tggaggctgg caactggcag ctcttagatg gtgtgcgaaa gcagctcgca
    46861 agccgatcat cgctgacggt gggatcagaa cacatggcga tattgcaaaa tctgtccgtt
    46921 ttggtgcgac aatggtcatg attggttcat tgtttgccgg tcacgaggaa tctcctggcg
    46981 aaacaaaagt cgaaaatgga atcgtgtata aagaatactt tggttctgct tcagaattcc
    47041 aaaaaggcga aaaacgaaat gttgaaggaa agaaaatctg gatccaacac aaaggatctt
    47101 tgaaagatac actagtggaa atgcaacaag accttcaatc atctatttct tatgctggag
    47161 gaagagatct ggaagccatt cgaaaagttg actatgtcat cgtgaaaaat tcgattttta
    47221 atggagacac aatctaaaaa ataaataaaa tattaggatg ttgtgaaaaa gttgtcctgc
    47281 attaagtaat aagaacagcc aaacaaaaat agttctttat atgttttgtt tggctggaat
    47341 tattatcgca gatacaagct tttgaacatc attattcaga ataagggact gtgataagat
    47401 ttttgtcaca gtcccttatg ttttgcaaaa aaagtttttc ttttttctcg taaattcggt
    47461 aaaatcaaaa gaaaaaatag acaatagaaa agagaagctt atgtgggaaa aagtagagaa
    47521 aaaacaagga ccgatttatc gtcaaattat ggaacagatt atgagagaaa tcgaaaacgg
    47581 aaggatcaat cctggaagtc aacttgaatc agaacgaaaa ctagggcaac tttttggtgt
    47641 gaatcgttcc accgttgtcc atgcattgga agagcttagg gagcttgggg tactaacgag
    47701 caaacgtggc agcggatggt ttgttaatca gactgaatgg gggaaattcg ctgttccaag
    47761 aatcgattgg cggcaaatga tctctcctcg ttatgagcag acggactggt atgagcaaaa
    47821 aataagagaa gcaaagcaga tccaaaaaac atcgtttctt gatttatacg ctagcgagat
    47881 gccagatgag cttttgccga attttgagtt tccttcttat tctcttgaag aaatcttagc
    47941 ggaagaaaaa gaaatggatc ttttaggcta tactccgtta cgtaacaaaa tcaaacggta
    48001 tttggaaagt aaatttgaat tggcattttc ccccaaccag cttcttgtga ctggtggcgg
    48061 tcagcaagca atctttttga ttttacaaac gattctttca gctggagagg ggatagctgt
    48121 agagtcacct tctttttttt accgattacc tcttttcaaa gcttcaggaa cgcgtttatt
    48181 tgggataccg atggatgaag aagggatcga cttagaaaaa ctgaaagaat cgatccataa
    48241 aaataaattg aaagcagtgc ttatcaaccc gaattttcaa aaccctacag gaaaagtgat
    48301 gagtcaaaaa cgacgagaaa agctagtaga attgtgtcga cagtatcggc ttccaattat
    48361 tgaagacgat gtatttacgg atctttcatt tctaaaccaa gaagaagtcc ttcctatacg
    48421 aacgattgat ccggataatg tgttatacgt cggttcgtta tctagggttt taggaaaaac
    48481 aacgaaaatc ggttgggtga taggacctga gacttttatc tcgcaactag ctcaagcgca
    48541 agaaatgatg gagttttcga tgaatatcct tacacaaatc acagtggcta atgtatttaa
    48601 tgaagcaatt gatttgaaaa tgcaagatgt aagaaaaaag ttgaaagaaa aaagccgact
    48661 gataagcgct tggggagatt cacaatcgtt tttcaagctt cattcaattt taggtggtta
    48721 ctatgcctgg attacttggg atgggaaaaa actagacccc gaactagcag aaaaagtagt
    48781 agatatgggt cttggaattg caccaagtct actttttggg caagatataa atggaatcag
    48841 aatcaattac agtaggctgg atgaaaacca aataccgttg ttttattcaa agatgaaaat
    48901 tctagaaaag tggttaacag aataatttca caaagtaaat agattaaaga atataacagc
    48961 ttggatttaa atttcaagct gtttcttttt tttcggaaaa agaatacgat ataaagaaac
    49021 taagaaaaaa ccattatttg tacgtccgtt cacgatgtgt aaataaaata aatgtttgca
    49081 acaaaactgt ataacaccaa cgtttttaaa tagaaacaga tggttgtaag tttgattaga
    49141 aaatagaaaa aatgcagatg aaatataaaa cgctttcctt attgtgattt tattcactaa
    49201 tgctgttaat atgcggattg gcataatttc ctttcatcgt gaaaatttgt gcttttagct
    49261 tgtatttctc ataaatccat gataatttat taatgaagac ggttaaatag tgatacagtt
    49321 ttattcactg tttcaatcgc agaatgaaga gattttctta tagatgagag aggaatgtgt
    49381 gacaaatggc aaacaaaaaa gcaccgatcg acttccaagc actgctagat gaagtcaatg
    49441 cagatttccc agtatatcaa gcacttgatc aagatggaaa cgtagttaac aaagatttag
    49501 tacctgattt atccgatgat gaactcgttg aattaatgac tcatatggta tggtctcgtg
    49561 tattagacca acgttcaaca gcgctgaacc gccaaggacg cctaggcttt tttgcaccaa
    49621 ctgctggaca agaggcaagt cagctggcta gtgcttacgc atttgataaa gaagatgttc
    49681 ttcttccagg ttatcgggat gtacctcaac tagtaaaaca tggtttacct ttatctcaag
    49741 cttttttatg gtctcgagga catgctgcag gtaattctta tccggaagaa ttgaaagctc
    49801 taccaccaca aattatcatc ggtgcacaat atgtacaagc agccggtgtt gcattaggtt
    49861 tgaagaaacg aaacaagaaa aatgtcgtct tcacttatac tggtgatggc ggttcatcac
    49921 aaggtgattt ttacgaagca atcaatttcg ctggcgctta ccatgcaaat gccgtatttt
    49981 atatccaaaa caacgggtat gcgatctcta cacctcgtga aaaacaaact gcagcaaaaa
    50041 cacttgcaca aaaagctgtc gcagctggga ttcctggtat tcaagtcgat ggaatggatc
    50101 cgcttgcagt atatactgta tctaaaatgg cacgggaatg ggcgatcagt ggaaatggac
    50161 cagtcctaat cgaaacactg acttatcgtt atggaccaca tacactatct ggtgacgatc
    50221 caacccgcta ccgtacaaaa gacacagatg acgattggca gaaaaaagat ccattgatcc
    50281 gcttccgtaa atatttgacg gaaaaaggac tttggtctga agaaaaagaa gaacaagtca
    50341 tcgaagcaac taaagaagaa atcaaagcag ctattgctga agccgacaaa gtaccaaaac
    50401 aaaaggtttc agatttcttg aaaaacatgt tcgaagtatc tccacaatca atcaaagaac
    50461 aaattgcaat ttatgaagcg aaggagtcga aataatcatg gcacaaaaaa caatgatcca
    50521 agcaatcaca gatgccttag cacttgaact agaaaatgac gagaatgtcg ttgtttttgg
    50581 tgaagatgtt gggaaaaacg gaggagtttt ccgggcaact gaaggattgc aggaaaagtt
    50641 cggagaagac cgagtattcg atactccttt agctgaatct ggaatcgcag gattgagttt
    50701 cggtcttgcg ttagaaggat ttcgtccagt tcctgaaatc caattctttg gttttatttt
    50761 cgaagcaatg gacgaagtag tagctcaaat ggctcgtaca agatatcgaa tgagcggcac
    50821 tagaaatcta cccatcacaa ttcgttcgcc atttggtggc ggtgttcata caccagaatt
    50881 gcattcggat aatttagaag gtttgatcgc tcagtctcct ggtattcgag tagtgattcc
    50941 ttccaaccct tatgatgcaa aaggactatt gatttcttct attagaagta acgatccggt
    51001 tgttttccta gaacacatga aactatatcg ctcattccga gaagaagtgc cggatgaagc
    51061 ttacgaagtt cctttggata aagcagcagt tactcgtgag ggaacagatg tatctattat
    51121 cacatacgga gcaatggtgc gtgaagcaat caaagcagca gacaatcttg caaaagaaaa
    51181 tatatctgtt gaaatcattg atcttcgtac agttgcgcca ttagatgtag aaacgatcat
    51241 tcaatccgtg gaaaaaactg gtcgcgtagt tgttgtccaa gaagcacaac gacaagcggg
    51301 cgttgccgcg caagtagttt ctgagatctc agaacgcgct atcctttcat tagaagcccc
    51361 aatcggacga gtttctgcac ctgatacagt cttcccattt ggacaagcag aaaatgtctg
    51421 gttgccaaat gcaaaagata tcgaagacaa agtaaaagaa atcgcggaat tttaagaaaa
    51481 gaagggacga aacaaagtca tggcttatca atttaaatt
//
LOCUS       DADQDV010000013        49987 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.013, whole genome shotgun sequence.
ACCESSION   DADQDV010000013 DADQDV010000000
VERSION     DADQDV010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 49987)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49987)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49987
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.013"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..1008)
                     /locus_tag="J8S10_000819"
     CDS             complement(<1..1008)
                     /locus_tag="J8S10_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAZ9629424.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(1188..1532)
                     /locus_tag="J8S10_000820"
     CDS             complement(1188..1532)
                     /locus_tag="J8S10_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HAZ9629425.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(1525..1959)
                     /locus_tag="J8S10_000821"
     CDS             complement(1525..1959)
                     /locus_tag="J8S10_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HAZ9629426.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            2097..2834
                     /locus_tag="J8S10_000822"
     CDS             2097..2834
                     /locus_tag="J8S10_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9629427.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            2827..4038
                     /locus_tag="J8S10_000823"
     CDS             2827..4038
                     /locus_tag="J8S10_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9629428.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            4245..5024
                     /locus_tag="J8S10_000824"
     CDS             4245..5024
                     /locus_tag="J8S10_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HAZ9629429.1"
                     /translation="MEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAAL
                     SREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLKT
                     MLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHGD
                     VNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDEM
                     LEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            5094..5756
                     /gene="trmB"
                     /locus_tag="J8S10_000825"
     CDS             5094..5756
                     /gene="trmB"
                     /locus_tag="J8S10_000825"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HAZ9629430.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(5854..7608)
                     /gene="ade"
                     /locus_tag="J8S10_000826"
     CDS             complement(5854..7608)
                     /gene="ade"
                     /locus_tag="J8S10_000826"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HAZ9629431.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNNQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            7740..8669
                     /gene="cpaF"
                     /locus_tag="J8S10_000827"
     CDS             7740..8669
                     /gene="cpaF"
                     /locus_tag="J8S10_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component"
                     /protein_id="HAZ9629432.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            8626..9675
                     /locus_tag="J8S10_000828"
     CDS             8626..9675
                     /locus_tag="J8S10_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HAZ9629433.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            9672..9950
                     /locus_tag="J8S10_000829"
     CDS             9672..9950
                     /locus_tag="J8S10_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HAZ9629434.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            9925..10395
                     /locus_tag="J8S10_000830"
     CDS             9925..10395
                     /locus_tag="J8S10_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HAZ9629435.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            10412..10714
                     /locus_tag="J8S10_000831"
     CDS             10412..10714
                     /locus_tag="J8S10_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629436.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            10731..11102
                     /locus_tag="J8S10_000832"
     CDS             10731..11102
                     /locus_tag="J8S10_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HAZ9629437.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            11074..11433
                     /locus_tag="J8S10_000833"
     CDS             11074..11433
                     /locus_tag="J8S10_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629438.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            11605..12612
                     /locus_tag="J8S10_000834"
     CDS             11605..12612
                     /locus_tag="J8S10_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAZ9629439.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            12637..13821
                     /locus_tag="J8S10_000835"
     CDS             12637..13821
                     /locus_tag="J8S10_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HAZ9629440.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(14258..15841)
                     /locus_tag="J8S10_000836"
     CDS             complement(14258..15841)
                     /locus_tag="J8S10_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAZ9629441.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIVLVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(16419..16562)
                     /locus_tag="J8S10_000837"
     CDS             complement(16419..16562)
                     /locus_tag="J8S10_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HAZ9629442.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(16785..17264)
                     /locus_tag="J8S10_000838"
     CDS             complement(16785..17264)
                     /locus_tag="J8S10_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAZ9629443.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(17337..17621)
                     /locus_tag="J8S10_000839"
     CDS             complement(17337..17621)
                     /locus_tag="J8S10_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629444.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(17699..17893)
                     /gene="ssrS"
                     /locus_tag="J8S10_000840"
     ncRNA           complement(17699..17893)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="J8S10_000840"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(17965..19251)
                     /locus_tag="J8S10_000841"
     CDS             complement(17965..19251)
                     /locus_tag="J8S10_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HAZ9629445.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            19389..20060
                     /locus_tag="J8S10_000842"
     CDS             19389..20060
                     /locus_tag="J8S10_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HAZ9629446.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            20026..20514
                     /locus_tag="J8S10_000843"
     CDS             20026..20514
                     /locus_tag="J8S10_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HAZ9629447.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            20527..21474
                     /gene="prmA"
                     /locus_tag="J8S10_000844"
     CDS             20527..21474
                     /gene="prmA"
                     /locus_tag="J8S10_000844"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HAZ9629448.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            21475..22239
                     /locus_tag="J8S10_000845"
     CDS             21475..22239
                     /locus_tag="J8S10_000845"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HAZ9629449.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            22472..24685
                     /locus_tag="J8S10_000846"
     CDS             22472..24685
                     /locus_tag="J8S10_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HAZ9629450.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            24696..25142
                     /locus_tag="J8S10_000847"
     CDS             24696..25142
                     /locus_tag="J8S10_000847"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HAZ9629451.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            25313..26572
                     /locus_tag="J8S10_000848"
     CDS             25313..26572
                     /locus_tag="J8S10_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HAZ9629452.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(26661..27608)
                     /locus_tag="J8S10_000849"
     CDS             complement(26661..27608)
                     /locus_tag="J8S10_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HAZ9629453.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            28002..29294
                     /locus_tag="J8S10_000850"
     CDS             28002..29294
                     /locus_tag="J8S10_000850"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HAZ9629454.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            29309..31078
                     /gene="aspS"
                     /locus_tag="J8S10_000851"
     CDS             29309..31078
                     /gene="aspS"
                     /locus_tag="J8S10_000851"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HAZ9629455.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            31187..32062
                     /locus_tag="J8S10_000852"
     CDS             31187..32062
                     /locus_tag="J8S10_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAZ9629456.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            32328..34211
                     /locus_tag="J8S10_000853"
     CDS             32328..34211
                     /locus_tag="J8S10_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HAZ9629457.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(34286..34570)
                     /locus_tag="J8S10_000854"
     CDS             complement(34286..34570)
                     /locus_tag="J8S10_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HAZ9629458.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(34560..35294)
                     /locus_tag="J8S10_000855"
     CDS             complement(34560..35294)
                     /locus_tag="J8S10_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HAZ9629459.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            35423..36046
                     /locus_tag="J8S10_000856"
     CDS             35423..36046
                     /locus_tag="J8S10_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HAZ9629460.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            36238..37359
                     /locus_tag="J8S10_000857"
     CDS             36238..37359
                     /locus_tag="J8S10_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HAZ9629461.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            37366..40494
                     /locus_tag="J8S10_000858"
     CDS             37366..40494
                     /locus_tag="J8S10_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HAZ9629462.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            40513..43707
                     /locus_tag="J8S10_000859"
     CDS             40513..43707
                     /locus_tag="J8S10_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAZ9629463.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(43853..44560)
                     /locus_tag="J8S10_000860"
     CDS             complement(43853..44560)
                     /locus_tag="J8S10_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAZ9629464.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
     gene            45316..45714
                     /gene="spxA"
                     /locus_tag="J8S10_000861"
     CDS             45316..45714
                     /gene="spxA"
                     /locus_tag="J8S10_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HAZ9629465.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
     gene            46046..46699
                     /locus_tag="J8S10_000862"
     CDS             46046..46699
                     /locus_tag="J8S10_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HAZ9629466.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            46925..47923
                     /locus_tag="J8S10_000863"
     CDS             46925..47923
                     /locus_tag="J8S10_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HAZ9629467.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            48099..49907
                     /gene="pepF"
                     /locus_tag="J8S10_000864"
     CDS             48099..49907
                     /gene="pepF"
                     /locus_tag="J8S10_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HAZ9629468.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
BASE COUNT        16169 a         8740 c        10454 g        14624 t
ORIGIN      
        1 ttttgatgaa tcagttgttt cttcagttga agattctttt gttgaatcag ttgattttgt
       61 gtcagaactc tttgttgaag ctgtagtttc acttgagtct ttcgtacttg atgaagttgt
      121 tgtgaatgca ctcaacacat tttcaaaggc atcatctttg atttttacat ttgcatcttt
      181 taattcttca ccgattactt tagttgtgaa tgcattgtca cttagtttag tttcagtagc
      241 gatatctttt agttgatctt tgtatttatc catgtcattg cctttatttt ggtttttcac
      301 cattttgaca acgtagtatt ctgtcgcata agaagtagga tttgttgtag taataacatc
      361 ggagatctca ccgtctttca atttgaaagc tgcttctttt acttctgcag gaatagttgt
      421 tgtcgttgag tcgaatttaa ctttaccgcc atcttctttt gtctctgtat cagttgattt
      481 gtctttggct aatttagaga aatcatctcc atcatccgct gattttttca catcttttgc
      541 ttcatcttca cttgataatt tgatgatttg tgcttctact tctggatgga aagatttcca
      601 agcagttttc aaatcgtcat ctgtaatatc tacgtgagct ttcaagccag cttcaaaagc
      661 taaattgtta cgaatatatt ctttataagt atctttcgta tatccagcag cttctaattg
      721 tgattcaaaa gtatcaccta atgatttcgc ttgtttgtcg tattctgcat ccacttgctt
      781 atcggttact ttatcgccat atttgttatt gaatacttta taaatgatca tccgttgtac
      841 taaggattgg ttcgatgatt caagttttgc ttcatcatag aaatcagata cagtgatcgt
      901 tccgcctttc atcgttgcga tatctttatt agtatcgcct gaacaagctg ctagagttaa
      961 aacagccaac gcactagtag ctgccaaaat aattgatttt tttttcatta aaatttgcac
     1021 tcctgtaatt agttattatt tttatatatt aactatacca tatcccattt cctttaaaaa
     1081 cgttgtcgtg gtagtttcaa acaaaattca aaatttcatc acattcctag gaaatacgca
     1141 aacttttctc acttatatag ttaaatctgt tgagaaaata atcattatta tatttgttca
     1201 ggatactctg gcagatcagc ttttagtttt tctacttgtt cattgatttg tgtgatacgt
     1261 ggttcggctt ggaatttaaa atcttcgata tcttttttga ttgcttcttg gaaagcagga
     1321 atcacagatt cagctgtttc ttttgtttcg atcaatgcgc ttttaaaatg attcaggctg
     1381 ttatttaaat catttgtcag agttgttgct tcttccaatt cttcgatcag tttctttctt
     1441 gtttcattcc cgctcctggg cgccaataac agacctccga cagtgccagc agcagctcca
     1501 aataacagtc ctttgaaaaa gtttttaatc atcgcaggac acctgcttta cgattgtttc
     1561 ttgaatagct tttagttctt ccgatccata actatcttga tgattgacaa agtgaataga
     1621 aaaatcatcc tctttgctgt agcgagggac taaatggata tgtgaatgaa aaacagattg
     1681 ataggctagt tcacggttgt tattcaagat attaagacct ttcatttctg gaaaagcttt
     1741 ttccaatgct tgagcaatct taggcacacg cgaaaaaacc tctcctgcaa gttcgggatc
     1801 atattcaaaa atatctgcta catgacgttt aggcacaact aatgtgtgtc ctttcgttgc
     1861 ttgagagatg tctaaaaaag catagacctt gtcgtcttca tatattttat agcttgggat
     1921 ttcttgattg atgattttgc aaaaaataca gttttccata taaaacatcc tttctataaa
     1981 gaataaatac ttcagcttaa ctttaccata agttaaagct attgtaagga aaaaaacaaa
     2041 ataccgtcat tttcttcgtg gtataataaa taaaaataaa tggcggagga aaaagaatga
     2101 gtttaattat cgatcatgtc acaggggggt acggacatct ccctgtgtta aaagatatca
     2161 gtttcgatgt acagcctgga gagatagtag ggttgattgg actgaacgga gcagggaaaa
     2221 gtacgaccat caagcacatt atcggtctgc tggaagcttc aaaaggaacg atagaaatca
     2281 atcatctatc cttaaagaaa aatacggaag aatatcgcaa acaaattggg tatattccag
     2341 agactccttc tttatatgaa gaattgacat tgagagaaca tatcgaagtc actgcgatgg
     2401 cctacgatat acctatggat atagcaatga aaagagcaga aaagttgttg gagacttttc
     2461 ggttatctaa tcgtcttgac tggttcccag ctaatttttc aaagggaatg aaacagaaag
     2521 tgatgatctt atgcgccttt ttgatcgagc cttctttata tatcatcgac gaaccatttt
     2581 taggcttgga tccactagct atcaatgcat tgcttgaatt gatggtagaa atgaaaaaag
     2641 aaggagccgg tattttgatg tctacgcata ttttagctac tgcagaaaaa tattgtgatc
     2701 gttttgtggt cttacataac ggagagatac gagcagacgg ttctcttgag atgttgagaa
     2761 aagaatttca gctgccggat tcttctttgg acgaaatcta tattgcttta acaaaggagc
     2821 aggcacatga gtagtttttt tcaaaaacgt ttagcaagac atcaaaagaa aatgatgaaa
     2881 tatatgcgtt atgtattgaa cgatcatttt gttttagttt gtcttttctt gattggcggt
     2941 gtgggattat attattctaa ttggttgaaa accctgcagc caccgtttgc aattggaggg
     3001 ctcataatct ctgtattttg gatgctctgt ttattcgtgg gtaagatggc tacttttgca
     3061 gaggcagcag atattgtttt tttacttcct aaagaaaaag aaatgcaaac ctatttggaa
     3121 cgagcttttc gctattcttg catttttccg ttgatctttt tgatattggc atgcggattg
     3181 gccatgccat tagtggtggt tagtacggag caatcctttt cgatgttttt cgtctatctg
     3241 atcatattat ggagtttgaa attcagtcat ctgcaaatca agagagcaga attgtttcga
     3301 ctagatcaac aagttattcg ttattggaaa ttaggctggt ttttttcttc tctgatcttt
     3361 ttgtttctat cattttattg gctaatatgg gcaggaatag caggtgcatt agtacaggca
     3421 agtctatatt actggttttt gtggaagcaa caagaaaaag gattggattg ggagaaaatg
     3481 gtgcatgtag aagaacatag gttgcatcag atctatcaat ttatcaattt attcacagat
     3541 gttcctgaaa ttacggcaaa gatcaaaaga agacgctatt tggatcctat attgactcat
     3601 attaaaagag aatcaaaaaa cacttatctt tacttgtttg caagaagatt ggcaagaggt
     3661 tctgatttta gtggtcttta tttccgatta gtaattatag gtgggttatt gattgccgga
     3721 gtagtcgact tttattttag tctgattatc ggtttcttat ttttatattt gatcggtttc
     3781 caactgttac ctttagcgaa ccagttccgc tatatggttc tcgttcagct ttatccaatc
     3841 cataagaatc agaagaagca ggcgattcag tatctactca catgggtatt aattatcgcg
     3901 tcggttattt ttggtttgat tgctgcagtc gtattagatg ggcagcagcg atgggttccg
     3961 ctagcggctt atttgattgt tactatgctc tttgttaaac tatatgtacc aactcgtttg
     4021 aagaagatgt cagactgaaa acaaagctgt gtagggtaaa aatgagaatg aaaaatagag
     4081 cgttgacagt aagaatgctg ttcgttctat tttttttgag aaaagctggt tttttgaatg
     4141 gcaattaaat gaaaaagaac gtatatgtgc ttgacgtgta gtgttcaggc gactagaata
     4201 ataagtactg caaaacaaag agtaagagga cgggagaatg catgatggag tttcagttag
     4261 accaagagtg gcggttacgt cccatcaaag gcgacacagg aaaaacatac ataggcatgc
     4321 gtgatgagga caaagtcttt attaaacgaa acacgactcc gatgttggct gctctttcaa
     4381 gggaaggaat tacaccaaaa cttgtttgga caaaacgaac ggggaatggc gatactttga
     4441 cagcacaaga gtggctggaa ggtcgcttgc tgactcctaa tgagattggt caaagaaacg
     4501 acgtgattga tgttttgtac catttacatc attcaaattc tcttaaaacc atgctgaccc
     4561 gtatcggtgg tcgtgtcatg acgccggaga agatgctgca aaaatatgaa aaagaattac
     4621 cggaagaact ccagaaaaat caatttctgc aaattgtcca tcgttttctt cgtgagcaga
     4681 tcccgtcaat agataaggaa aacttatcag tagtacacgg agatgtaaac catcgtaatt
     4741 ggttagtatg taaaaattat ttatatctag tcgattggga ttcaatcatg tttgcagacc
     4801 ctgcggtgga tattgcaacg attttaggaa attatgtgcc actgtctagc tggaatcagt
     4861 ggctgatcag ttatggcata cgcccgactg acgaaatgct tgaaaaattt cattggtatg
     4921 cggccatgaa tttgctccaa gaaatcacca gatattgcaa acgtgaagat catcgacgga
     4981 tgaacgaaga aattttacaa ttaaaacgaa ttttcagtgg ctgaggtttg gcccaaactc
     5041 tgcggagatt tggccagacc tttttaatta gaggaaagga atggagataa ataatgcgtg
     5101 tccgaaatcg tccgggagca gcggaaatgt tagcggctca cccgaatttt gtaattagtg
     5161 atccaacatt gtggaaggga aaatggaatg aattgtttga aaacgatcat ccaatccaca
     5221 ttgagattgg tatggggaaa ggccagttca tcactggaat ggcaaaagcc catcctgaaa
     5281 tcaattatat tggagtagaa atgcaggtca gtgttgtttc gattgcacta gacaagttga
     5341 tcgaacaacc gcttcctaac ctgaaacttc tacatgtgga tggatcagcg ttgacagagt
     5401 atttcgctga cagcgaagta gatcaaatct atctgaattt ttccgatcca tggccaaaaa
     5461 aacgtcatga aaaacggcga ttgacatata agacttttct tgctgtagat gaacagattc
     5521 ttcgtccaaa tggagaaatc catttcaaaa cagataatca aggattgttt gagtattctc
     5581 tggcaagttt ttctcaatat ggcatgatcc tcaaacaggt atggttagat ttacatcaaa
     5641 gtcaatttga aggcaatatt atgacggagt atgaagaaaa attttcttca aaaggtcaac
     5701 gtatttatcg agtagaagct caatttcaag ataagaccaa aaagaaaagt ctgtgaaact
     5761 aactttctgc tttcataaaa acattaatat ccataaataa atcccagaaa atgaacatta
     5821 cagatgtaat gtattttctg ggatttattt gatttaaaat gtatttattt catcggtttt
     5881 tccacaaggt ggaatcaatt ggaagcgaga aaatgaaaat aatcctttgt cggtgatctt
     5941 caattcgggt atgacagata atgttaagaa agaaagtgtc aaaaaaggat caaaggtttt
     6001 agctgctcct agttgatgtg ctttagttat taattcattc aactgttcat agacgatcga
     6061 aaaaggttcc tgtgtcatga ttccgcctat aggaagagaa acacaagcta tttcctgctg
     6121 attgttgaca acggtcatcc cgccaccttt ttgaatcaaa agattagcag catacagcat
     6181 atcctcgtcg tttgtcccaa cgacaactag attatgcgag tcatgggcaa tcgttgtcgc
     6241 tatcgctcct tgtttcagct gaaatccttt cactatgcct aatccaatgt ttcccgtttg
     6301 atggtgacgc tcgatcaccg caatctttaa ttggtctttt tcgattgaag gaatgaatcg
     6361 ttcgccttgt cggtccactt tttctaccaa atctttagtc actagactat tcgggataat
     6421 ttcgatcaca tgggcttgtg aagaagaaag aagcagctct aacgaatgtg gatttaatgg
     6481 ttgagcgttt agttttggca gacaacacgt atatgaattt gaatgatcag caaataaatg
     6541 gtcttggagt tgcccagatt gaacaactaa tgttccctta tagaaaactt catgaattgg
     6601 cagcttggta agatcgtctg ttaagaagaa atcagcttga tacccagggg caatcgcacc
     6661 tagtgttttc aaatcaaaac attctgctgc attcaatgtt gccatctgaa tggcttgtaa
     6721 tggatcgatt ccaagtgcaa tagcttgacg gacgatatga tcgattgatc cttcttttac
     6781 taaatcattg atcagtttat catcggtgac aaagaagcat cttcttgaat tttcaggtgt
     6841 gatcgccggt agtagcgatg ccagatcttt tgcaacggtc ccttctcgaa ccattaaata
     6901 cataccaaga tccaaacgtt ctttagcttc ttttgcagtt gtagcttcat gatccgtccg
     6961 aatacctgct gcaggataaa catttaactc ttccatgccg ataccagctg catgcccgtc
     7021 aatttttttc ttatgctggt gcatcaattg gatcttttct aggatgtctg tttcattatt
     7081 tgctactgct tgatagttca tgacttcagc taagcctaaa acttcgggtt tttgtaaaaa
     7141 aggggctaat ttttttgcat ttaaatttgc accattggtc tcaaaagggg ttacaggtac
     7201 acaagaaggt agcataaaaa agatattcat gagtgtttgt cttgcatctt ctatcataaa
     7261 ctcaagacct gtactcccag caatgtttcc tatttcatgg ggatctgtca ctacagtagt
     7321 aactccatga agcaaggata cttttgaaaa ttcgcttggt gataaaagtg agctttcgat
     7381 atgcacatgg ccatcgatga atcctggcac tagatattgc ccattagcat tatgtacgct
     7441 ttttccttcg tattcaccga ttcctacgat cattccttcg cagattgcta catctttttc
     7501 catgatttct ttcgtaaaga cgttgacgat cttagcatgc ttgatcacta ggtcagcagg
     7561 ctttttttta cttgctactt cgatatattt ccttaatgtt gtttccaatg gagtgcctcc
     7621 caagataaat ttttataagt ataacataaa ttcggttttt gccaatattt ttttgtaaat
     7681 tcattttatt tgaaacaaaa agatcaaaaa gacgtatgtt ttttgtggag gggagaataa
     7741 tggaaataaa acgattatcg gatcaaatga taagtgaaag ttttgccaaa catgcccaag
     7801 acgtatatat attgccagct tcagaagtat tttacatcta ttttcgctat ggaaaaaaac
     7861 gaacattctg gaagaaagtc tcttcggcag atggacagca actgatctca agatttaagt
     7921 atttgggaca gatggatatc ggagaaaaaa gaaaagctca gttaggtgca tttacttatt
     7981 ctttagaaaa acaggaagtt cgtctgcggt tgtcttctgt aggagattac cttcaacgag
     8041 agagtttagt gattcggcta ttatacggta cttttgaaac accccatcgt tgctttagtt
     8101 ctcgagattt tgcaactatt ttacagaaaa ccgtcagacg tggattatac cttttcagcg
     8161 gaccagtcgg atcaggcaag acttctctaa tgtatcggtt ggctttggaa gaaaaattgc
     8221 aagtgattac tatcgaagat cctgtagaga tagaagaacc gttttttctg cagctacaga
     8281 tcaatccgaa aatagcacag acttatgata cacttttgag actcgcatta cggcatcgtc
     8341 cagacttgct aatcattggc gagataagag atgaatcaac tgcacatgct gcggtaagag
     8401 cagcactaac agggcaccgg gtttttgcaa ccgtacatgc acgcaatctt gaaggtacat
     8461 tggtcagaat ccatgaactg acaaagaaaa aagaagagct atctgaatgt ttagctggtg
     8521 tcatttatca agaacttttg gaagatgcca atcaccatcc ttctgtttta tggagttatc
     8581 aatttatgga ggaagaatca gtaaaaaaat catgggagga aagttatgaa gaagctcagg
     8641 aaaatatttg gcagtcagaa ctattctaaa ggattaacaa gaagccagca aaaccagttt
     8701 gcacaaacca tgggagaact gcttttatct ggttttagtc tgcaagaatc cctttattta
     8761 ttactcacga tccgttcgtt tccacctgtt attttggcaa atatccaaca tcagctaaag
     8821 gaagggcaag cgtttagtga ggtactttcg caaataggat atggagcaga gcaactggta
     8881 cagatcgagt tagctgaacg tcatgggaat ctgccgacaa ctttgttgga aattgccaaa
     8941 cagtttcggc ttgttgaagg atttcgcaat gatttgaaaa agctgcttgc atatccgatg
     9001 ctattgctca cctttttgct aggtatcttg tttagtatgc ggttgttcgt tttgcctcag
     9061 cttattggtt caggaatggt catgcaagag cattggggta ttcagctgat acaagtcttt
     9121 cattggtatg ttctactatt catcctagcg gttactctat tggctttact agtaaggtat
     9181 cgtctgatga agttgtctcc tgttgatcag agtgaatgga taagcagaca attattgatt
     9241 ggaccgatat attccttgta tcaatcggct tatttgtcac tagagattgg aaagcttttt
     9301 catgaaggtt tcgaattaag gcaaatcata gtctgcttaa aggaaacgaa acaagaaagt
     9361 ctgattcagc atcttgcctc taagttgatt caaggattgg aggcaggtat gtcattggct
     9421 gagcagttcc agaattatcg ttttctatca gaagaattca gtaaaattgt tttacaggga
     9481 gaggcaaagg gaagtttagg taaagaactg attttttaca gcgaatggac aagaaaacag
     9541 cttttcaaac gtcttcatca ctggatgcat tttattcagc caatcatttt tttgggcgta
     9601 gcggctttga ttttattagt ttatgccgct gttttattac ctgtttacgg aagcatagag
     9661 gaggttttgc catgaaaaag agaaaaatat cttattatag cggttttaca ttgatcgaaa
     9721 tgctaatcgt cttactgatc atcagtgtat tagtgttgtt gttcgtccct aatttgtcgc
     9781 gttataggaa tcatgtagac caagaaagtc gtgaagcgat catccagttg gtagacacac
     9841 aaaaagagct ctatgcgctt caaaataatg gaagagttcc tactgtggag gaattgttga
     9901 atgaaggcta tatcaaacga gaacatgcag aaatctatca gcggccttga aggtaaggtt
     9961 ttagcatcag gatatacgtt gtttgaatca ctcttactga ttttattact tacaacgatc
    10021 ctttcttttc cagttctcgc attttctgca tggaagaatg aattggcagt ctatcaattt
    10081 ttcggccaat ttgaaaaacg aatctattct acgcaaaaaa tcgctattgt gaatcagatc
    10141 caaacaggct tttattggaa tagtgaagag aatcaaatca tttttcatgt tccgaatcca
    10201 gataaaataa attgggaagt attagatatt cctgatgaga ttaccttgaa acgccatgct
    10261 tctattactt ttgctgctag aaccgggaat gaaagttcac taaaagctta tcaattttat
    10321 tgggaagaaa aagagcggac gattacgtat caattccaga tagggagtgg tcgctataca
    10381 aaaagaattg aataaaacag gatttgtttt gttggagtcc cttacagcgc ttatgatcgc
    10441 ttctgtctgt gtctacttag tgagctttgg ccagctgttt ttgcttcagg cagaaaagaa
    10501 aagtggggag gaactgctat ttattcgaat gatttatgaa gatatcaaga cgcagcggat
    10561 gtatcacaaa agaccagagc gaagggaaga aatgatccca tacgatatcc aaattgtcga
    10621 taataatgga gtaatcgaaa aagtgtttgt caatatggag aaagaagcga tcagtattga
    10681 aaaaacaagt aattccagca tttacgctga ttgaatgtct aattggactg atgatattga
    10741 gcagtctatt gctcacattc aatcttttga ttcagcaaac catccaagta agtgaatttt
    10801 tgcagcgtaa agatcaaaaa gagtggctaa tatttttagc acaattagaa gaagaactca
    10861 agagcagtca caatgtctct gtgaaaaatc agcaactgca ctacacgatc gaggataaac
    10921 agtatatcat cgaaagatat caggcaatga tacgtaaaag aagaacttcc ggcggacatc
    10981 aacctatgtt aacaagtatc actgagcttc aattattgga aaaagaacac acaatttctt
    11041 tttatgtaca ctttgaaaat ggagaagatg gatatgccat atggacaaaa aacgatcagt
    11101 agaaaatgtt ataagggctc tattttattt tctgtcttgc ttttatttct tttatgtacg
    11161 tttttattga tggcagcatt agaaagctac cgtttgtcaa tggatcttaa tatacgaatc
    11221 aaaaattatt atatagcaaa aataatgaag cagatggctt tatcggaaca gtctacgctt
    11281 gccgaaagtt cggaaggagt tttttactac acaactggat ctgtaacata tcagtgggta
    11341 caacagtccc tattcttaga ggtggaagtc tcaccgttta tctttcggtt cacagaagaa
    11401 gtaaaaaatg atacagatac tagtacagaa tgatggaatg ttcgtgaaaa cgccctcttt
    11461 tctgttataa cactgttttt aataaaaaaa tgtttgccgt ttcacaaata aaaaacagtg
    11521 aaaacgattg aaattttgtc aattgttcga tagaattaaa caggtgaaaa aattgttata
    11581 atatatctag aaatgaggtg caccatgtta ccagaaaaaa tggaacaagg gtttaatcaa
    11641 aacctggaag ctattcagct tttacagaat gcattgggaa cttccttttt agaagcctat
    11701 gtcgaaaatg cagaaaattt aatagatgat tatcaagtac gtgtggtgga tggagtgccg
    11761 acaaaagaga caacgcaacg gatcacagct ctttatgaag agttgaagaa actttctttc
    11821 gagccagaag aatggcgcag actgtctcaa ttacttttat tgaagggcag ccagacagaa
    11881 catttgcagg cgaaccatca actcactcct gatagtatcg gttttttatt tgtttttctt
    11941 attgaacaac tatacacaaa taaaaaagca ccggttaaga ttctggatat tgcggcagga
    12001 atgggcaact tgttattaac agttctttta aacctatcga atgcggggta ccaaacagaa
    12061 ggaattggtg tggatattga tgatacattg ttggctgtcg cagcttctac aagtgatttg
    12121 acacaagcaa atgttcaata ctttcatcaa gacgggttgc aggaattatt aatagatcct
    12181 gtcgattttg caatcagcga tttgccaatc ggttattatc cgaatgacga aaaagcaaaa
    12241 gagtttttaa caagtaccga agaaggccat agttatgcac atcatttatt gctagagcaa
    12301 tcaatgaaat atgtgaagcc ggatggtttt ggtttgtttt tgatgccgag tggattttta
    12361 gaaacggatc aaagtgaaga aatcaaaaaa tggtttaaag aagaaggtta tcttcaagga
    12421 atgattcaat tgccagatga attgttccgt aataaacaat cgcaaaaaag tattttgatc
    12481 ttacagaaaa aaggaccaca agcacaacaa gtaaaagaag tcttgcttgt gaaacttgct
    12541 tcattaaaag aaccagagaa ggtgacggaa tttttcaacg agtttaaaaa ctggaaatca
    12601 tctgctctgt aatcattcaa cgagaaggag agtcatatgt ctaaaacaat tgcaatcaat
    12661 gctgggagtt caagtttgaa atggcaatta tatcaaatgc cagaagaaac cgtagttgcg
    12721 aaagggatcg tcgaacgtat cggtttacaa gattctattt ttaccatcaa gtacggcgat
    12781 aatcaaaaat tcgaacaaat catggatatc gaaaaccacg aagtagcagt aaaaatgctg
    12841 ttagatcagt tgattgaact gcaaatttta agctcttatg atgaaatcac cggagtaggg
    12901 caccgtgttg ttcacggagg agaaacttat ggggattcag tagtgatcga tgagaaagta
    12961 atggaccgca ttgctgaatt agcagaattt gctcctttgc ataatcctgc aaacttaatg
    13021 gggatcaaag cgtttaaaaa gattttacct gacattttga gtgtggctgt attcgataca
    13081 tctttccact caacaatgcc aaagcaaaat tatttatata gcttaccggt gtcttattat
    13141 gaagatttca aagtaagaaa atatggcttc catggcacaa gtcatcgtta tgtgtcggaa
    13201 cgtgcggcaa aattattgaa caaaccgatc gaagaactaa aaatcatcac ttgccactta
    13261 ggaaatggtg tatcgatcac agcagtcgat ggaggtaaat ccatggatac ttctatggga
    13321 ttcacaccat tagctggggt gacaatgggt acacgttcag gtgatatcga tccagctgtt
    13381 ctcccatatt taatggaaaa attagagatt gatattgatg aaatgatcaa tgttttgaac
    13441 aagaaatctg gtctgctagg cctaacagga ttgtctagtg atatgcgtga tcttgaaaag
    13501 aactatgaaa aagaacatat tcgtttagct tatgacattt tcgtggaccg catccgaaaa
    13561 tacatcggcg gttatgtgac aacgatgaat ggtgttgatg caattgtctt tactgctggt
    13621 atcggcgaga atgacggaca tgtacgtagt gaaatcatca aaggtatgtc ttggtttggt
    13681 tgtgaaatcg atccagcgtt gaatgaattg cgtggtgaag aagtagatat ctctacaaaa
    13741 gaatcaaaag taagagtatt agtgatccca acagatgagg aactaatgat tgcccgtgat
    13801 gtggagcgtc tgcgcggcta agccaaagca ttcgttagga taaaagatga aacgcatgca
    13861 agagggaatt cttgcatgtg ttttttttgc ggagaagacc gcaaaatggt aatttaactt
    13921 caatttccct tcttttttac aggatcttct tagggaattt tgcttggaaa agtggtcaaa
    13981 agggaaaaga ctggcatttt atttattgat tttcaggaaa atcccaatat tttattttca
    14041 ttcatcttta taagggacat tacatatgta aaaagaaaaa acatttttag atcagcctcg
    14101 tgggctgtcg actttattct tcgctttatg tttagctaga aaaccgatcc gaaacattca
    14161 ttgatcgaat aataaaaact tgattttcca cctgtacttt gcctgaatcg tgaaagcaca
    14221 ggtatgaaaa tcaagttttt tgttgcgaaa aaacgtccta gtcaatcagt tggccgagcg
    14281 gctggcggct gatctgctcc tgatcaataa cgagtgcttc ttggaagtgt tgctgcaaaa
    14341 agtagcggtc atggctgact gctaggagcg ttccttgata gtcttgcagc atttcttcaa
    14401 tttcttctcg agcatagctg tcgaggtgat tggttggttc atccaaaatc aggacgttga
    14461 ttttttctaa aaagagtttc agcaacgcca aacggatttt ttcaccaccg gataaatctt
    14521 tgatccgttt acccacatcg ctttgataaa agccactttt ggctaattgc cgtcgagcga
    14581 cttcttcgtt tccagtcaat gtgatggcgt aagccagcaa acggctatcg ggatcggcaa
    14641 actgcagctg ctgcggcaaa taaccgattt gcaagctact acctaatttg atggtgccac
    14701 cgtaaggctt ttcctcaccg agtaataatt tgagtaaggt tgattttcct gcaccattgt
    14761 cgccgatgat ggctaaatga tctccacgat agactgcaaa actgctgtct ttgaatagta
    14821 cttgatcagc gtactgctgg tgcaagtttt gaatgatgaa aacttctttg ccagattttc
    14881 caccattaga caagctttgc agccgatttt tcgggggagg tggcggtttg acgagtgtca
    14941 gtttcgccag gcggcgttcc agttctttgg cttttttgaa gaaggactca ttgtctcctt
    15001 catgtgccca ctgacgaaaa cgacgaatca tgactttcaa ccgctggact tctttttgct
    15061 gcagttcgta attttttgtc agctcagcca agcgagcttc tttcaagact cgaaaacggc
    15121 tgtagtttcc gggatactca atcaatgcac cttcttccag ttcccatgtt tttgtggtga
    15181 cttgatcgag aaattgccga tcatgagaaa cgaccagaac cgattttttt gtattctgta
    15241 aatagttttc caaccagcga atactgttaa gatctaaatg attggtcggt tcatcgagta
    15301 aaagtaaatc ggcatcggct gctaaaattt tggctaaagc gactttaact cgttcgcctc
    15361 cgctaagttc tgttaaccgt gcttcctgac ggtgtggaat ccctaagcct tgcaagatcg
    15421 ctgcaatccg gtcttctaat acgtaaccgc ctagttcttc aaagcgatgc tgcagctcac
    15481 cgtaacgggc cagacacttc tctaagtttg tatctggttc tgtcatcaat gcttcgtagc
    15541 gactcatttg ctgtttgagg tcctgtatct cagcggcaga atggagcaag tagtggttga
    15601 cggtcgcttc ggaaactgta agttcttgtt cgaccgtccc gatctttaag ccttttttgc
    15661 gactgataac accgctgtcg acaccttctc tgccggtcaa gatttgtaaa aaggttgatt
    15721 tgccagttcc gttgataccg actaagacaa ttttttcacc agcttcaatt tgacaggata
    15781 aatcctcaaa taatggattc ccgccgattg tttttttaat agaaattgct tgtatgatca
    15841 tgatctctct ccttgagacc actcaaaaag gccatggtta tccatggcct gtgttattta
    15901 aactcagatt atcatgagaa aaataccttg agatggccat tgattttacg tgaattcaac
    15961 tgttttggac aaacttgtcc cgtcaacagc aactgtaaaa ccaattgcat ggctaaatgc
    16021 gatatggtat cgttggtaat tttcattact tgttatttta gtcatgcgca tcatagtatt
    16081 ttccctcctt cgtgtagttg tcttttccag tgtacctgaa agtgtcagaa agttcaacta
    16141 gcgctgacat ttacttaata tttatcgatg tgtaattctg tcagagagct ttttttatct
    16201 gactgagggt aatgtctcgt ggaccacatc attgtattct gagctaaacc agcgttcagg
    16261 cgaaatcata tggtgtttga taaaaaactt tgtctacatg acttcctttt gccatttgct
    16321 taataccgtt gcattaaaca gctcttctct ttggaaatct caccaacatc gcgttcagga
    16381 gtatcgttgt ggttgcaatg gcaagcggta gcctttcatc aattcttgaa tgatttaccg
    16441 aatgtagcac ttgccttctc gcggtacccg aacccgaaat aaaattttag tttggcgata
    16501 aaatcggtat ccgccatcga tacttcatat tttttcgtat cagattcatc ggaaacttcc
    16561 acattgacga accaataagc tttggcatgc ttaggtcgtt ttaaaccaca ccagggcgac
    16621 taatcgccct ggtgttcact tttttttatt ttacttgaac tcattgactg ttttcccttt
    16681 attttaaaca ttataaagac cgatgagtgc ttgccgcgtc ttttgttttt atcacggttt
    16741 tttgtgcaaa aaaacctgcc gatagttggc aggtcgtcta cgtgttaagc tttggtgtgg
    16801 tctttagctg gcaattggtt ttctaaatca gttcggacaa caagcacatc gcaagctgcg
    16861 tttctaataa catattcaga aacagaacca ataaataaac gttctacagc attcaatcct
    16921 gtggctccta acataatcaa atctacttga ttatcttctg ggatttctct ggcaataatt
    16981 tgttttggtg agccatattc tacgacagag gttacattat tcaagccagc tttcttcgca
    17041 ttgctttcat aatctgccaa tgtttgcttt gccatttcag tagcttgttc tgcaagcatt
    17101 ccatcaaagg atgaaacggt ttggaaagaa cgtgtgtcaa tgacatgtgc taatagaagt
    17161 tctccgttat ttcggatagc tacattgacc gcctttttaa aagctaattc agcttcatca
    17221 gaaccatcta cggcaaccat gatttttttg tattgttgta acataagcat tcactcctca
    17281 agtcaatcgt attgtactct tttattgtag aacactttag ggaaaaagag aattatttac
    17341 tgctttggtt cagcaatttt ttttgcaaat cggatactga aggtggcaga aacaataatt
    17401 acgatcagta aaaagaccaa ggcaataaag cgttgattga aaaaagctgt taaaataccc
    17461 attacgccta aaacagcata tgcagctccg taaaattgta ggaatccttg atttttatca
    17521 tttttgttga tcaatacaaa aaagatatcc tgtttattaa ataaataata gctaacgaat
    17581 aataatacta aagtggcgat aatcattaaa atcctaatca tgaacaaatc ctccaaaata
    17641 agcaacaaat agaaaaagca atttgccaag agcaaattgc tttattcttt aaaagatggt
    17701 aatctccgtt aatgccgttg tttgtcctgt agtattgatc ccgcgaattc aagcaggtgg
    17761 gtcccatggt cgtagcttcg aactaccaaa tgataaggca tgttaccagc agtgacacaa
    17821 gacgggtccc aagatatcaa taaaaatgtt cggtcaacac acaaagagga caattcgaac
    17881 atcacagatt tcccacctct atagtagcat atgaatttaa aaagagcaat gagagagctc
    17941 gcagaaacag aaccgttttc ttgtctagtt ttttggagga tgctttttcc actcttttat
    18001 acggtaatac tgttgaccca gagcctgttc atatttccct gtatcttttg gctgataata
    18061 ctgagcattc ttcagtttat ctggtaaata ttgctgattg acccaagcct gatcaaaatg
    18121 atgaggatac tgataaccca cgccacggtt gagtgatttc gcacctttgt aatggctatc
    18181 tctcaaatga tcaggaacat ctccagcttt gccctctcga atatcagcaa gtgctgcatc
    18241 taatgccatg taggcagaat tggattttgg cgacaagcaa agatcgacga cgacgtctgc
    18301 tagtgggata cgtgcctcag gcaatcccaa tttttcagca gctaatacag cgttcactgt
    18361 acgagccgca gcagcaggat tacctaaacc tatatcttca taaccgataa ccatcagacg
    18421 ccggcaaata cttgccagat cacctgcctc aactaaacgg gcgagataat gaagtgcagc
    18481 atccacatca cttccacgaa tcgatttttg aaaagccgaa ataacgtcat aatgagcatc
    18541 tccatttttg tcatgggtaa gagcttttct ttggacacat tcttcaatga tcgacagtgt
    18601 aagatgaatc cttccttctt tatctgaagg agtcgatagt gtagccagtt ccagcccatt
    18661 caatgcactc cgcaaatcgc cgttcgttgc acgcgaaagg tgaagaagag catcttcgtc
    18721 taactggatt gcttgttgtc caaggccgcg ttctttatcc cttaaagcat gttcgactgc
    18781 caactggatg tcttgttctg ttaatggttt gacttcaaag atctgtgtac ggctgcggat
    18841 cgctggattg atggtaatat aaggattctc agtagtcgct ccgatcaaga tgattcggcc
    18901 actttctaaa tgaggaagca gaaaatcctg ttttgtttta tctaatcggt gtacttcatc
    18961 caataagagg atcactgtac cactcatttt tgcttcttcc gctacaactt gtagatcctt
    19021 ttttgaatct gtagcggcgt ttagcatgcg aaatgcataa ttagtagagc cggcgatcgc
    19081 acttgcgata ctcgtttttc cagtaccagg aggtccatat agaatcatgg aagagagcat
    19141 gcgagcatcg accatgcggc gtatgatttt tccttccccg actagatgct gctgaccaac
    19201 gacttcatcg atcgttcgag gtctcatgcg ataagccaat ggctgttgca taggattttc
    19261 ctccttcttg tttttacgtc ccttaattat atcatattta gcaagatgcc tagaaagaac
    19321 agccttctgt tgttttgttt tcatagctta tccaactaat attgtgtatg ataaagtagg
    19381 tgagaaaaat gacggataaa caaaagatag atgaattttt ttggaataaa acgacgccag
    19441 aagtggcacg ggatttattg gggatgtatt tggagcatga cacaccagaa ggaagattag
    19501 ctggatatat tgtagacgcg gaagcatacc taggtccaga agacgaggcc gcccatagct
    19561 atggtttaag aagaacaccg cgtgtgcggg caatgtatga aaaaccaggt acgatctacc
    19621 tttacacgat gcatactcat cggattttga acatcattac tcagccagaa gggattcctc
    19681 aaggagtaat gatacgtgca atcgaacccg ccgcaatgat tgatcaaatg agtaaaaatc
    19741 gtggcggaaa aactggtcca gatatcagca acggtccggg aaaattagtg gaagcattag
    19801 caattcctca agaactttat ggtcagtcta tagcagatag ttcgttacgc ttagtttttg
    19861 agaaaaaaaa gacaccaaaa aagatcaatg ctttgcctag aatcggtatc ccaaacaaag
    19921 gtgtatggac agaaaagccg ttgcgttttg ttgtgtcggg aaatccttat atctctttac
    19981 aaagaaaaaa ccaaatcgag aaagattggg gttggaggaa agaaaatgaa aaagaaggat
    20041 ctattaacat atttagatga aataattgaa aaacaagtga cagactatga tgtagcttta
    20101 gattgggata caaaaaatca tacgatcgag atcgttgttc gcttgtttgc agaaaataaa
    20161 gcacaatttg agattgatga tgcagaaggg atcgtttcgc aagaaccaat tatcgaattt
    20221 gaagacggcg tacttctttt taatcctcag aaatctgttt ttgatgaacg caattatcta
    20281 gcagtaatcc cttatgaagg aaaaaaaggg ttggcaaaat cagtagctga ttctttagtg
    20341 gaatatctaa atgaagtatt agctcaaggg caaagcgatt tgcttgattt tttggatgaa
    20401 gacgatgacg aagctgtatt cgagcttcac tgggataatc agcaactagc agaattagta
    20461 gaagtaaaac agcaaaatga agcagatact tatttaccgt acccaagtta ttaaggagtg
    20521 acagatatga aatggaatga agtaaaagta gaaactgaaa gtgaagcagt cgaagcagtt
    20581 gctaatattt tgatggaggc aggggcgagt ggtgtcgcga ttgaagattc tttagatgtt
    20641 gaacattttc agtcggatca atatggtgag attttagata aaaatgattt tacatcgctg
    20701 aaagaaggcg cactagtcat ggcttatttt ccggaaacga ctttcttacc ggaaatcttg
    20761 ccttttatca aagatcgtat cacacaatta cctgagtttg gtctagctat tggaaaaaat
    20821 aaagtaacag ttagtgaagt agaggaaagc aactgggcaa cagcctggaa gaaatactat
    20881 catccggtgc gtattacgcg aatgctgacg gttgcgccaa gctgggaaaa ctaccagaca
    20941 gaagatcctc tagaaaaaat tatcacacta gatcctggta tggcatttgg cacaggcact
    21001 catcccacga cttccttgac attgacagca ctagaaacag tcttgcgtgg tggtgaaaca
    21061 ttgctagatg tgggaactgg gtcgggcgtg ctaagtattg cagcaaaata tcttggtgca
    21121 aaagatgtct atgcctttga tttagacgaa gtagccgttc gttcggcgaa agaaaatatg
    21181 gatatgaatg aaatagccaa agatgtccat gtatcagcta acgatctttt gacaggaatc
    21241 gagattgaaa gtgatgtaat cgttgcgaac attttagcag atatcatctt attgatgatc
    21301 ccagatgctt ggcgtttact gaagcaaaca ggcacgctga tcgtttcagg aatcattgaa
    21361 gagaagaagc aaatggttct ggatgccatg ttagaacaag ggtttatcgt ggatcaaatt
    21421 ttccagcaaa aagactggta tgcaattatt ttgaaaaaac cagaggtgga atagatgcag
    21481 cggtattttt taaaagaatc atatgaatca aaagactatt ttgttttaga aggggaaaac
    21541 tatcaccaca ttgtacgggt tatgaggatg gaacccgagg atgaagtttt tttggcattc
    21601 aatgatcaaa tagccattgt tgcagaaatc acggagatta ctgaagaggc tgtttatctg
    21661 aaagaaatta aaaaagaaga aaatcaaaag gaactgccaa gttcgattac catagcgagt
    21721 ggctatccta aaggggaaaa gctggattgg atcgttcaga aatccactga attaggagcg
    21781 caagcttttc ttggtttccc ggcatcagcc tctgtcgtta aatgggatgc aaaaaaacgt
    21841 atgaaacgac aacaacggct tgaaaagatt gctcaagagg cagcggaaca atcccatcgg
    21901 cagatcgtgc catcagtaga gttattggaa acgaaacaag atttatttga gcggctagat
    21961 gattatgacg tggtcttggt tgcttatgag gaatcagcaa agcaaggcga aaaatcaaat
    22021 gcagccaaaa ttcttagtga aacaaaacca gatagtcgaa tcttagctgt ctttggacca
    22081 gaaggtggat tatcccgcga tgaagtcgat tattttgtag aacacaaagg gatactttgt
    22141 ggattaggac caagaatcct tcgtacagaa acagcacctc tttatttatt aagtgctgct
    22201 agctatcaat gggaattaat gaatccttct ttcagctaac gttcttcatt aataaaagag
    22261 tatcgacaga aagaattgaa aaaatagtca acaatttgta taatagaaac aattatttat
    22321 acaatggata cgaaaaatcg tttgaaaaag cttttaaaaa gcgaacattt ccgtaaaaaa
    22381 acgtataact gcacggattt tgggacaatt atcaaacaga tatttgtccc gattcccgtt
    22441 ttaccgaaaa aagaaagggg gatcgattcc tgtgacaaaa gaagaaattt taacgggacc
    22501 cggtgtcata aagctcgtta gtcaatacat gggtcccgaa catgtagcat ttgttgagaa
    22561 agcatgcgaa tacgcgactg ctgcacatga cggacagttt agaaaatcag gcgaacccta
    22621 cattattcat cctatccaag tcgcaggtat attagcagat ttaaaaatgg atccccatac
    22681 agtggctaca ggcttcttac atgatgttgt tgaagataca gaaatcactt tagaagatct
    22741 gagagaagaa tttggcgatg acgttgctat gttagtggac ggcgtaacca aattagggaa
    22801 aataaaatat aaatcccacg aagagcagct agcagaaaac caccgaaaga tgctgctagc
    22861 aatggctcaa gatttacgag ttatcatggt caaattagct gatagactac ataacatgcg
    22921 tacgttgaag cacctgcgag aagataagca aagaaggatc gctcaggaaa ctttagaaat
    22981 ctatgcgcct cttgcacatc gtctagggat cagccggatc aaatgggaat tagaagatac
    23041 agcacttcgt tatctaaatc caaaacagta ttaccgtatc gtccacttga tgcagacgaa
    23101 gagagaagaa cgtgaaaaat acgtaagtgg tactgttgaa gatattcgaa tagcgacaga
    23161 agagctgggg atttttgcag aaatctatgg acggccaaaa cacatttatt caatctatcg
    23221 taaaatgaaa gatcagaaaa agcagttcaa cgaaatttat gacttgctag ctattcgagt
    23281 gatcgtagat tcaatcaagg attgttatgc tgtattagga gcaatccaca caaaatggaa
    23341 accaatgccc ggcagattta aggattatat tgccatgcca aaagctaata tgtaccaatc
    23401 tttgcatact accgtgatcg gtccggcagg aaatccggta gaaattcaaa tccgaacaca
    23461 ggaaatgcat gaaatcgctg aattcggggt tgctgcacac tgggcctata aagaaggaaa
    23521 aaatgaaaaa gtagaaccag atggtatgac gaaacaatta agctggttcc atgagatact
    23581 cgaacttcaa gacgaaagct atgatgcttc tgaatttatg gaaggcgtaa aaggagatat
    23641 ctttagtgat aaagtctacg tcttcacacc aaaaggagac gttactgagt taccaaaagg
    23701 atccggacca ttggactttg catacagtat ccatacagat atcggtaaca aaaccactgg
    23761 tgcaaaagta aatggcaaaa tggtgcagct tgattacaaa ttgaaaaacg gagatatcat
    23821 tgagatcatg acttctccaa attcatttgg cccaagtcgc gactggttga aattagttgc
    23881 tactagcaaa gcaagaaata agatcaaacg tttcttcaaa gcccaagatc gagaagaaaa
    23941 tgtgatcaaa ggccacgaat ccgtggtcaa atgtattaca gatctaggat ttacgcctaa
    24001 agatattttg acgaagaaca aactgcaaga agcactcgat cgttttaatt atcaaacaga
    24061 agatgatctc tatgcagctg tagggtatgg agaagttagc cccttgacga tggccaatcg
    24121 tctgactgaa aaagaacgta aagaacaaaa aatcgagcag caaaagcaag aagcagaaga
    24181 aatcatgaat cagccgaaaa aagaacctga caaaatgaaa gtacgtcatg aaggtggcgt
    24241 tgtcattcaa ggggtagaaa acttactaat tcgtatcagt cgctgctgta atccgattcc
    24301 tggtgatgat atcgttggtt atatcactaa aggcagaggg atatccattc atcgtcgaga
    24361 ttgtccgaat gttcagcctg acaaaccaaa tgtagcagaa cgtttgattg aagtcgaatg
    24421 ggaagataca tcgaatacac gaaaagagta tgatgcagat ttggaaattt acggctataa
    24481 tcgttcaggc ttattgaatg atgtacttca aacagtcaat gcgctaacga aaaatctcaa
    24541 cagcgttgaa gcacggacga ataaagataa aatggcgacg atccatttga cggttggtat
    24601 ccagaattta tcccacctaa agagtatcgt ggataaaatc aaagcagtac ctgatgtcta
    24661 cagtgtacgc cggacgaatg gataggagga cagatatgag agcagttgtt caacgggtaa
    24721 gtaaagctgc tgtgtcagtc gatcagcaag aaattggaaa aattggctac ggcctacttg
    24781 ttttattagg cattcatgaa accgatacgc aaaaagatgt ggactatctg gtaaaaaaaa
    24841 ttgcacaaat gcgtattttt gaagatgaac aaggaaaaat gaatattagt gtagaagatg
    24901 tgggaggaca aattttaagt atctctcaat tcacactgtt tgcggatacg aaaaaaggaa
    24961 atcgaccaag ctttgtggaa gccgcacgac cagaaacagc tattccttta tacgaatcat
    25021 tcaatgaagg aatcagaagt cgcggcatca cagtcgctac cggacaattc ggagcagata
    25081 tgtcggtttc tctcgtcaat gatggacctg taacgatcat tattgattct aaaaacaaat
    25141 aaagtaatct ggttttcact agtaaaaact atgaaacacg tcgcttaagt tagactgata
    25201 aactctaact taagtggctt ttttgtctgc aaaaagcgct tcttttgtca gcagtcggaa
    25261 aaaaagttaa gcttaaatta tacaagttat tttttatagg aggttgctga agatgaaaga
    25321 agtaccagta gtagatatca aaatcacaga tttaaaaaaa ttgtatcaaa aaggatacaa
    25381 catgttggag gagttacgcc atgaagcgga cgctcccgtc gtcaaagcaa agattttcaa
    25441 taaagaagct atcacgatct acggatcatc agcagcaaaa gtattttatg atccaaggaa
    25501 tttcaaacga aaaggtgcta tgccaaaatt agtattgaag acactttttg gtcaaggtgg
    25561 agtacagact ttggatggag ctgctcatca ccatcggaaa aatattttta tggatctaat
    25621 gacaccggaa agaatggaag attatcatcg tatcttagat aagaatctga cacaagcact
    25681 tgaagcacag catggtcaat ttgaactatt tgatttaagt aagatggttt tctttacatc
    25741 tatttgcgag tgggcaggta tcaatttatc agcgatttct aaagatgagg tcgaaaaatt
    25801 agcagaatat caaatctcta tgatcagcgg aacgtttact tctccgattg atcacataaa
    25861 aggtgtcgaa aatcgcaaaa aatcagaaaa atgggcgcaa ggcttgattg aagaagctcg
    25921 acaaaatcct gtggctggaa aagaaaatgt ggcattatat gcttttgcca atgccacaga
    25981 tttagatggt cagcttttac ctctggaagt ggcagctgtt gaattattga acatcatccg
    26041 tccaacggtt gctctaactg tgtgggcggc attgatggga catgcacttt tcagtagacc
    26101 agatttgtat cagcaattaa aaaatgactt ttcgacgtta caagatccgt ttattcaaga
    26161 aatgagacgc tattatcctt tcttcccaat gctacctgcg atttcgctga aagaagtaga
    26221 agtagatggt tatcgtatac cagaaggcag ttgggttatt ttagatttat atggaacaga
    26281 ccatgatgaa cgaacagttg aagcgccaga ttcctttatg atcaaacggt atgtagggaa
    26341 agcaaaagat atttcctata aagaagaata tgagatgatt gcacaaggcg ggggaaattt
    26401 tcgacaaatg catcgctgtg caggagaatg gatcactctt catagtctac gtgtgttttc
    26461 cgatcagcta gtaaataagt ttgagttctc tgtacctgaa caagattgga cgattccatt
    26521 caatcagttt ccgacttatc cgaatagccg agcgctactt tacaagaatt agattagcat
    26581 aaacttatcg aaaaaaagga agatcaaaca gtgctgatct tccttttttc atattactat
    26641 aaattgataa ggtcaattga tcaaaatcca cgaaatgctt catcaatggt ttgataatct
    26701 tcattggata aatgcaaatc taaagcttgg acattgtcag atacttgctc tggacgctta
    26761 gctccaggta taactacaga cactcgtgga ttcttcatgt accaagctaa aacaagttgc
    26821 gcaggagtgg cttggtatct tttagcaatg gggcgaagta catcgacagc ggttaaaatt
    26881 tctctgaaac gttctccttg gaaatctgga tttctttttc gaggatctcc ttcaccaaat
    26941 tgtttttcct caccaagttc atattttcct gtcagcaaac cggaagcaag aggaaaatag
    27001 ggaacaaaac tgattttgtt tttttcaaga taagggaata attctttttc agcctgccga
    27061 tggatcaaac tgtatttatc ttctactaca tcgacatatc catctgcatt cgcttctttc
    27121 aattgttcta acgtgaagtt tgacacaccg actgctcgga tttttcctgc ttcttttaat
    27181 tcgtgcaatg tagcaactga ttcatttttt ggtgtgcttt catccggaaa gtggatataa
    27241 aaaatgtcga tgtaatcagt ttgcagacgt tttagtgcat cttccaccga ttgtttgaga
    27301 aactcaggag aattatcaaa tgttcgccct ttatttggta catgagcagc ttttgtagcg
    27361 atgacgacac gtgagcgatc atattctttt tccttcagta cctcgccaat cagttcttcg
    27421 gaacggccgt ttccgtaagc ataagcggta tcgatcaaat tgatcccgct attcaaagct
    27481 gtacgaacta cttgttttcc tgtctcatct tccaaaccgt caaaaagatt atgtcctcca
    27541 acggcatttg ctcctaatcc aagctgttct gcgtagactt gtgaatgtcc gattcttatt
    27601 tctgccatag ctgattcctc ctttttgtct agtctaaaac aaaataccaa aaagctgaac
    27661 taaaacgttt ttgtgagggg aaatagtcag atatctcttg actttgagac tggtttttag
    27721 taggttataa gtaatatcga atgtcaatga aagagcgagt aagtttttga aactttacaa
    27781 gagaggatca tcgaggctga aaatgatcta aagtttcatt agcctaaaga cactctggag
    27841 atggacgagt gaaaagccgt cccgcgtacg agcgttattc gtaagaggaa agagaaatct
    27901 ttcaaaatta ggtggtaccg tgtatgaatt tcattcaccc ttgttcatga tgaacaaggg
    27961 tgattttttt atttacatag ctaagaaagg gagagaaaac tatgagtttc caaagaccaa
    28021 aaggaacaaa tgatattttg ccaggcgaat cagaaaaatg gcagtttgtc gaagaaacag
    28081 cacgtttatt attcagagat tatcagtata atgaaatgcg tacaccgatt tttgaacact
    28141 atgaagtgat atcccgaagt gtaggggata caacggatat cgtttcaaaa gagatgtatg
    28201 atttttatga caaaggggaa cgccatgtga cgcttcgacc agaaggtaca gcaccaatcg
    28261 ttcgttcttt tgttgagcat aaattgttcg gcccagagta tgcgaaaccg ttcaaaactt
    28321 tttatatggg accaatgttt cgctacgaac gccctcaaaa aggacggtta cgtcaattcc
    28381 atcaaatcgg agtagaagca tttggatcag aaaaccctgc aactgatgtg gagagcatgg
    28441 tgatggcact tgatttcttc aaacagttgg ggatcacgca aatccggcta gtcatcaatt
    28501 cattaggtga taaagaaacg cgtcaagcct atcgtcaagc attgatcgac tatcttttac
    28561 cttttgaatc agagctgagt gaagactcta aacgccgcct tcatgaaaat ccattacgcg
    28621 tattggacag taaagacaaa cgagatcaaa aatttgtggc agaagctcca tctatcttag
    28681 attatctaag cgagcctgct caaaaacatt ttgataccgt tgtttccatg ctggatgcat
    28741 tggctgttcc ttatgaaatc gacagtaata tggttcgcgg actagattat tacacacata
    28801 cgatttttga aatcatgagt gacgcaccaa aaatgggggc acaagcaacg atttgcgcag
    28861 gcggacgtta tgacaatcta gtggaagaac taggtggtcc ttcaacacct ggcttcggat
    28921 ttgcaatggg tatcgagcga ttactcttga ctatggaggc agaggaagta gttatccctg
    28981 catttaatga gttggatgct tacgtggtcg cactcggaga cgaaacaaat atcgaagcat
    29041 tgaaagtggt ccaagcgatt cgaaactttg gtttttcagc tgaccgcgac ttcatgaacc
    29101 gtaaagcaaa agcgcaattt aagacagcag ataaagcgaa tgccaaatta gtattggtga
    29161 tcggtgaaga tgagcttgct agtcaaacga ttaatgtcaa agcaatggca agccgaaaag
    29221 aaaaaagttt tccattagaa gagatatatg aacattttga tgaagtctat gatgaaatga
    29281 ctttattcga gtaggaggaa aaaaataaat ggcacaaaga acgatctatt gcggattagt
    29341 ttccgaacaa caattagaac aaacagttac attaaaagga tgggtacaaa aaagacgaga
    29401 ccttggggga gtaatcttta tcgacctacg tgatcgtgaa ggaatcgttc aaatcgtctt
    29461 taatcctgaa atcaacaaag aagcatggga aatcgcggat aaatgtcgca gtgaatacgt
    29521 gatcgaagtg actggggaag ttagaagacg cggagaaaat gcagtaaatc ctaaaatggc
    29581 cactggtgaa ttcgaagtga ttgcaagtga aatcgtgatt ttgaatcaag caaaaacccc
    29641 gccatttcaa attgaagatg atcaagcaat cagtgacgaa atacgtttga aatatcgtta
    29701 tttggatctg cgtcgtccaa aaatgactaa aaacatcaaa ttaagaaatg cgacaacaaa
    29761 agcgattcgt cattatttag atgataatga ctttctcgat atcgaaacac cttacctagg
    29821 gaaatctaca ccagaaggcg caagagacta cctagttcct tcacgtgtcc atgctggaca
    29881 tttctatgcg ttgccgcaat ctcctcaatt gtttaaacaa ttgctgatga atgctggatt
    29941 cgaccgttat tatcaaatcg ttcgttgttt ccgcgatgaa gatttacgtg gagaccgtca
    30001 gcctgaattt acgcaagtag atattgaaac aacgttctta acagcagaag aaatccaaac
    30061 ttacacagag ggattgattg cgaaggtaat gaaagaagtt cgcggtatcg aagtcacatt
    30121 gccatttcct cgtatgacct atgatgaagc aatggctcgc tacggcagcg acaaaccgga
    30181 tacacgtttt gatatggaat tgatcgatct aagcgataca gtcaaagaag tagaattcaa
    30241 agtcttccaa atggctcttg aaaacggcgg tgtcgtgaaa gcattgaatg ctaaaggcgc
    30301 tgcagatcgc tactcacgaa aagacatgga tcagttaggt caatatgtag gacaattcgg
    30361 agctaagggg cttgcatggc tgaaagtaga agaagacgga ttgaaaggtc caattgctaa
    30421 attcatggga gaagcaacag aagcaatcat taaagcaaca gatgcaaaac caggtgactt
    30481 gctgatgttt ggcgcagata aaagtgaaat cgtcgctgct gcattaggtg ctatccggac
    30541 acgtttagga aaagaattag gactaattga tgaatcgaaa ttcaatttct tatgggtaac
    30601 tgattggcca caatttgaat tttcagaaga agaaggtcga tatgtctctg ctcaccatcc
    30661 attcacgatg ccaaaagaag aagatatccc gttattggct gaagaccctg caaaagtcta
    30721 tgcagaagct tatgatatcg tcttgaacgg ttatgaacta ggcggaggtt ctatccgtat
    30781 tcatactcgt gagcttcaag aaaaagtact agaaactcta ggctttacaa aagaacaaat
    30841 ggaagaacaa tttggtttct tgttaacagc tttagattac ggattccctc cacatggcgg
    30901 tattgcatta ggattggacc gttttgcaat gttattagcc ggagaagata atattcgtga
    30961 agtcattgcc tttcctaaaa acggaaaagc agcagatgtg atgagtgatg caccaagtat
    31021 ggtttcgcct ttacaattgt tcgaattgaa tattgatgta acgaatatag aagaatagcc
    31081 gataaaaagg taaaaaggat ttgtcgaata cgcttctttt gacaaccttg atttaattga
    31141 aaaacacttt ataatgaagc cataacatat aaagcggggc ttttccatga aaaaaacatt
    31201 cgaaaattgg gcttatcatg attacacgac caagctttcg gtatctatcg tttatgcgtt
    31261 gatcgcatca gtcgcattga atttctttta tcagccagga catatttatt caagtggtat
    31321 tactggtcta gctcagattt tgacgacttt gtcaaaatca ctgataggat tcgaagtacc
    31381 ggtatcaaca actttgtatt tactgaatat acctttgttt gtattggcgt ggttaaaaat
    31441 cgggaagaag tttacaattt tcacttttat cacagtcact ttgacctccc tttgtatcca
    31501 tattttaccg gaaacagtcc tatctaccga tccaatcatc tgtgcgttgt ttgggggggc
    31561 tgtgatggga ctaggtattg ggctagcgtt gagaaacggc ctatcatcgg gcggtctaga
    31621 tatcgtgagt atcacgattc gtaaaaaaac aggaaagtcg attggttcta tttcgatcta
    31681 cttcaatgca ttgatcgttt ttgttgccgg aattctattt ggctggcaat atatgtttta
    31741 cagtacgttg tctattttcg tcagtggaaa agtaactgat gtcgtttata ctaaacaaaa
    31801 gaagatgcag gtaatgatcg taacgaaaca tccagaaaaa gtagtaaatg aaatccaaaa
    31861 ctgtatgcgt agagggatca cgatcatcaa tgaagcagaa ggtgcttata agcatgataa
    31921 gcagacagta ttgatgacga tcgttacacg atacgaactg cctctactta gagaagcaat
    31981 gaaagcttct gatccacaag cttttgtaag tattgcagaa aacgtccaga tacttggtcg
    32041 tttctatgag gatggcattt agatcgagtt tgacaaaaat tcatgaaata ctgctgtaga
    32101 cagacgttcg tttgtctgca gtttttttct accatagtag aatcagcaaa gaaaaactgc
    32161 ttttttattt gaaattttct taaagttgaa aaaaagcatg tttatttttt taaatttatg
    32221 ggatgataga aaaaaatagt agagaaagga cacgattcta cttgctattt tcacttaata
    32281 cccgtatatt acgaatgaaa aaagtttatg aaaagttgga atattgaatg gaaaaacaaa
    32341 aaaggttaaa aaacagccgc tacatcactg ggtttgatgg gctccgttca ttagctgtgg
    32401 tgggtgttat cttctatcac cttctgccaa ctagtatgaa aggcggctat ttgggcgttc
    32461 cgattttttt cgtcgtatct ggttatttga tcacggatct gctgcggcag gaatgggaac
    32521 aaaatggaaa aatcaatatt tggcaatttt atgtcagaag aatgaagaga ctctatccgg
    32581 cacttgtttt tatgcttgtg acagcttcgg cttatatcac tttgtttcag cgagggctgt
    32641 taaacaatct tcgaggagtt gtggtcagca gcttactgta tgtcaacaac tggtggcaaa
    32701 tcaataacgg tttatcttat ttcgatcgat ttgctaatga gtcaccgttt acgcatatct
    32761 ggtctttagc agtagaaggt caaaactatt tggtttggcc gatcttgttt gtattgttga
    32821 tggtatttgt tcgtaaaaga aaatggatct tttatactgt gttaggtaca tccttcctct
    32881 ccgccatctt gatgatgatc ttgtatacac caggaggcga tccaacccgt gtttattacg
    32941 gtaccgacac tcgtctgttt tctatatggt tgggaagtgc gcttgcgttt gtttggccaa
    33001 gtacgcgttt aaagaaaaac atcccgaaac aagcgaaaaa tattctgaat atcgctggag
    33061 gaatctcgct tttggcactg attctttgct tcttcttttt agatgatcat tacaatttca
    33121 tctattacgg aggaatgctc ctagtgagtc tgttatgcgt agtgctagtt gcagtgacag
    33181 cacaccccgg agcaagtttg aatcgatggc tgacaaatcc agtatttact tggattggca
    33241 aacgaagcta tggcatttat ctgtatcagt ttccagttat gattttttat gaagcaaagg
    33301 tgactgatat tgccgatcat gttttgttgc atactttagt ggaaatcaca ttgattctaa
    33361 tcatcagtga actttcttat cgatatgtgg agcgtccgct agcacgtttt gattatggtc
    33421 gtacattcca agtgatgaaa ggatggttca gcaaaccgat catcagtaag agcaaaccat
    33481 gggttgttcc aggcacatta cttgtagcaa ttgcactcgt tggtttcgtt acggcaccga
    33541 aaaacgctgt aacagccgat caaaaacaac tgcaggcaaa aatcgctgaa agtaaaaaat
    33601 tagcagaaga aaccagaaac aattcagaaa acaccactag ttcggttgac caagcgatcc
    33661 ttgataagta cgagttgtcc aaggcacaag ggaataaggc acaaaaatta gaactaacgg
    33721 catttggtga ttcagttatg ttggatgctg caacggatct acaagaactt tatccaaaag
    33781 tagtggtaga tggagatgtc ggacgacaat tatatgccag tgtaccgtac attgaaaaat
    33841 taaaggaaca agatttgttg aaagacactg ttctgatcgg actaggaacg aatggctcat
    33901 tctcggaagc tcagtttgat agtgtgatgg atgcaatcgg tgatcgaaaa gtatactggg
    33961 tcaatgtccg agtaccgacg aagcgctggc aaaatgacgt gaatgcgatg cttgaacaga
    34021 tgacgaaaaa atacgacaat atgacgctga ttgattggta cagctacagt aatgaccata
    34081 gtgactggtt ttatgatgat caagtccatc caaatcctga agggatgaca cattacattc
    34141 acttagtcag cgaagccttg ctaggaggaa gttcaagtac gaacagcagt gagacaaacg
    34201 tgacagaatg atagctacaa aaaacttcag gcaaaaacat ttgtttttgc ctgaagtttt
    34261 tttatattta ccgtgttttt aacattcata tagattcagg aagcaaaacg gttgagtgtg
    34321 tctgtaaata acgttctttt tgttttcggg tgagtttttt gaatgcagct tctgcttttg
    34381 ttgcttcgct tcttgaagaa aatacttctg catggatcat cttaacaggt cttctttttt
    34441 gaagacgagt atatttagca ccagtaccat tgttatgttc ctctaatcgt ctagaaagat
    34501 cggttgtata tccaccataa aatgtctgat ctttacagaa taatacgtaa aaataatgtt
    34561 catttgccat agagcatctc acgaatctct gcagtgtatt ctccatccat attgtaagtg
    34621 atcaatggtg gagcgacttt gaatccgtct aatttgcctt ctttgattcc ttcaactaac
    34681 aaaatatttg cctcttttcc aggttttggg taaacaaatt ggatcctttt aggtgcaatt
    34741 cgatagtctt ccatgacctg aatgatttct aagaaccgat caggacgatg gaccatagta
    34801 aagcgtccat ttgtttttag tagcttactt gaaatatcga tcacttcttc taacgtcgta
    34861 tgaatctcat gacgggcgat tgccaggtgt ttattagggt tcgttttatt tgttggcagc
    34921 cctttgaaat aaggtggatt acagacgact aagtcacaag aattatgtcg aacgacagat
    34981 aagctgtctt tcagatcgat ggtgtggaca gtcatttgtt catttaaatg gttaagcgcg
    35041 atactacgtc ttgccatgtc tgctagacga ggttgaagtt cgatagcgtc gatagccgcc
    35101 tgggttcgtt tacttaaaaa aagtccaact gcgccatttc ctgcacaaag gtcaacaatc
    35161 ttcccttttt taggtacacg ggaaaagtga gcaagcagca cagcatctaa agaaaaagaa
    35221 aacactttgg aactttggat aatcttgata tcttctgcgt ataattggtc gattcgttcg
    35281 tcttcgtgaa gcatggattc cctccaaaat gaaaaaaata gtcgtctgta ttatactatt
    35341 tttattaaaa agaaccaagg tggcttgtca aacctctatt ttttatgcat actatgacca
    35401 taagaaggga aaggaagaga ctatgtttta tcgatttatg cgcggggtag ttcgagtact
    35461 attagcctta gttaatggaa atgcccgcta tgagaataaa gaagttttac cgcaagatga
    35521 gaattacata ctagttgctc cccatcgtac ttggtgggac ccattatatc tggcggtagc
    35581 tgcagcaccc aaggaattca gctttatggc aaaagaagaa ctgttcaaaa atccagttct
    35641 gcgatttata ttaactcgat ccaatgcttt tccagttaaa agagaaaatc caggaccaag
    35701 cgtcattaaa acacctgtaa agattttgaa atcgacaaat ttgagtttga tcatgtttcc
    35761 cagtgggaca agacatgcta cagaacttaa aggcggaatg gcattgattt ccagaatgtc
    35821 taaagcgaaa atcgtgccag ctgtatatca aggtccgttg acacttgggg atctgttcaa
    35881 gcgtcagaga gtgacagtgc gtttcggcga accaatcgac ttatcagata tcaagaaaac
    35941 ggataaagaa ggtatggcgg agatcgaacg acgaacacaa gcagcttttg acaaattgga
    36001 caaagaagtg aaccctgatt tcaaatatga agtcaaaaaa aaataaaatg ataagtttat
    36061 gcgtgggcgg tcttttgaat ctactgtcct gttcagttca gactttttca atgaaaacga
    36121 gggagagacg tcaagtctgc cctctttttg cgttccaata tgtaaaatag aagacaggtg
    36181 tcatgtaatg gatcaaagtg ttataataat tagaaggaca ttttttgagg tgattgaatg
    36241 cgttttttac atacagccga ttggcatatc ggaaaaaaac tacaaggtta tgacttgatt
    36301 gaagaccagc gtcatgtact atcttctata ctagatatcg cgaaagaaga aaaagtagag
    36361 gcaatcgtga ttgccggaga cttatatgat aggagtgtcc cagctgttga tgccgtagaa
    36421 ttatacaatg aattgatggt cgattggaat ttaaaggaaa agatcccgat ttttgctata
    36481 tcaggaaatc acgatagcag tacgagactt tcagcgggta cgccatggtt cagttattcg
    36541 aactattttt tgcgaacaca gctagcagaa gcatttgaac cagtcgagtt taaaaacgta
    36601 caatttttct ttcttcctta ctttgaacca attgcagcga gattatattt tgaagatgac
    36661 aatatccgaa cgatcaagca agcggtagcc aaggtgatag ataaaatgca ggagctattt
    36721 gattcagaaa aaaaacaagt attgattagc catttttttg taatgggaag tgtaaaatct
    36781 gattcggaaa cgaaaatcga agtaggcggg ttggattcga tccctggtga actacttaca
    36841 ccgtttgatt atgtagcact aggacatttg cataatcaag ctgctttgag acaggataat
    36901 gctcgctata gcggttcccc attgaaattc tctttatctg agatcaacca aaaaaaaggc
    36961 gtatggatcg ttgacctgac aacaggcctg gagttgaatt ttagggagat cgaacccctg
    37021 catgatattg aagaaataac agcgagtttc aaagaattgc tggatcctgc cttttatcag
    37081 tccgtcaatc gggagaatta catctatatc tatctcactg atagaacgat catcccgaat
    37141 atgatgaacc agcttcggca aatatatcct cgtattttgg ggattgaacg ggcaaacggt
    37201 cgagcagaac aaacaaagcg caaacgaaaa gtactagaaa tgaaagatcc tcaaaaatta
    37261 gcagaagcat tttttagtga aatgacggaa gagcagctaa ctgcaaacca agaaaaatgg
    37321 ctcggagaaa cgttgcaaga aatcatggaa atggaatgat caagaatgaa accgaaaaaa
    37381 ttacaactta aaaattttgg tccttttatc aatgagaccg tagatttttc acgtttgaca
    37441 gaagcaccgc tttttttgat cagcgggaag acaggagctg gcaaaacgac gatttttgat
    37501 gggatcacct tcgcactttt tggtgaaact tccggaagac ttcgctctgg aaaagagatg
    37561 cgttctttgt ttgctacacc agacgaagaa acaagcgtga ctttttcttt tgaacatcag
    37621 cagatgagct atgaaatcga acgaaaacca gaacaagttt tagcaaaacg aaaaggaaac
    37681 ggaacaaaaa aacaggcagc caaagtaacg ttgaccattt ttgatgggaa aggaaaagaa
    37741 ataaaacaaa tcacaaaacg tacagaagca gatcagttga tcagagaact gatgaatctc
    37801 gatgcgaaac agttttctca aatcgtttta ctaccccaag gagaattccg taattttttg
    37861 gtttcatcaa gcagtgataa agagactgtt ttacgtcatt tattcggtac tcaatttttc
    37921 caacagttca atgagcgatt aaaagaaaaa gcaaaacaac agcaacaaaa attggatcat
    37981 ttagagcaag agctgcatct tctgcaaaaa aggtttgttt tagtcaaaga agaggaacca
    38041 gcagcagggt ttgaagccgt tttagcccaa tggacaaacc atcaggcaat actcgaaaaa
    38101 caaatcacgg aagaaaaaga agctctaacg gaacttcagg aaaaacaaaa gcaactagaa
    38161 aattcctact atcgttttga aagcttgaaa aaaagttatg aagaaaaaac gatattaata
    38221 aacaagcaaa aggaattagc tgctcaaaaa gacgaaatag aggaaaagaa acgatggatt
    38281 gggtattatg aatttacgca acgattagtc gaaccaatcc agcgcctaca agaaataaaa
    38341 gttgaaaaaa tagaactgtc acaaaaaagt agtgagcaaa caaagaaact agcgatgact
    38401 acgcagaatt atgaagagtg gcaaaaaaat gaagcaaacc gcgtacgccg acaaacaaaa
    38461 atcaaagaag ctgctcaaaa actgcaaaac aaacagatga tggtgccaat tgtcgaatcc
    38521 ttacgtagta aaaaacaaga cgcagaacaa ttaacaattt cattggataa agaagaattg
    38581 aatgccgaga agctgtatca aaatctcgct atctatcagg aaagaactcg aattcttcaa
    38641 gaaaatttac tggatcagga aaaactgcaa gaagatcgtc ttgcttttgg acagttaaaa
    38701 tatctagatg aaaagcagca agaaatagaa aaacaaaaag caaaagacac tgggtcgctc
    38761 gcacagataa gagaagaact caaaaaagca actgaagaaa taacaaaaaa tagtcagcta
    38821 ttgaaagaac agacagaaca agcagaacag ctgaaaagcc aatgggcaaa gcagcaaatt
    38881 gctcgtcttc agcttttttt gcgtccaggg gagccatgtc ttgtttgtgg atcaacggaa
    38941 caccccatac aacaattaaa acacgaacag ccaaataagg aagatatctt aaaagtagaa
    39001 caacaactgg cagaagctga gtctgctgta gaaagaactc agcaaatcat tgccaaaagt
    39061 gaagcacatg aaaataatct tcaacaacaa ttatcagatt tagaacaaaa aatcatggca
    39121 acgaatatac aattggctga acaagaagaa cacttgcaac aggctttgaa aaaggcattt
    39181 cctgagataa cagaacaaaa aacaaaaaca actcttgtag taatcgaaca atctttagat
    39241 agacgaaaaa gcaagatggc caatgcaaga atagagctgg aagaaataag acaacaagca
    39301 gaaaagctcg aacaacaatt agctgtctac aaacagcagc agacagaaaa aaataatcag
    39361 ctccagcaac tgcaaggaga aatcaaaagt ttagaacaac aattgcaaga tacggatagt
    39421 aactgtttag aagaggagat acgacgactt gaaaaacagt tagaagaaga ctcgaatcaa
    39481 ctagctgttg agcagaaagc aggagtgcaa ttgttgcaag atcttcatac gcttcggaca
    39541 cagcttgatc ttcaacatga acaaatagaa aaaatagatg aaaaaataga aaaggaacaa
    39601 gaaagaatag ctaaaaagtt agaaagccag tcgtattttt caacaattga agaaatctgt
    39661 gcatttgcac aacagcaagc acaatataaa gaaaaccaac gtacagttac ttcttatcat
    39721 gaagagcaat tagtgacagc tgaccggctg cgtcaattag aaaatatcca gctaactgag
    39781 acattcccag atacagaaga gatcagccaa cagttagaag aaataagacg tatgatcgaa
    39841 ataaagcaag aaaagatata cggtttacaa gaacaaaaaa ttagtaatca aaaaatctac
    39901 gatgaatgtc tttcgattta tcacacaagc cagacgaaat tagatgagct tacgcaatta
    39961 cagcagcttt cgcaaacatt caacggagaa aatcctaaga agactagttt ggaacggtat
    40021 gtgcttcagg tttatcttca agaagtgtta caagtagcaa atgatcatct ccaacgttta
    40081 acgaaaaatc gttatcaatt tgagctagcg gataccattg gcagttatcg agggaaaacc
    40141 ggattagaaa tcaatatcta tgatgatcag gcaggtatgt ctcgaagtgc gcataccctg
    40201 tctggcggtg agagttttat tgcagcactt tctttagcat tagctcttgc cgatgtgatc
    40261 cagacacaag ctggtggtgt agcaatcgat gcattgttta ttgatgaagg atttgggtca
    40321 ttagatgaag aagctttgga aatggcaatg gaagctttag aaacgatcga aagtgaagga
    40381 agaatgatcg gcatcattag tcatgtaaga gaattgaaag aacgagtatt acaacaaata
    40441 agaattgata cagaaggtag cggacaaagc aaaatacgct atcaacttgg ataaaaaggg
    40501 agattggtaa ctatgaaatg gagtattcca gaaaaagtca ttgcacgtgg acgtcaatac
    40561 ttgcaagaag gccgagtgtt atcggttgtc cctgaccaag aagaaaacgt gtggcatgca
    40621 gaagtcttgg gcagtgaatt gtatatggtt gatttggatg gtacagcaaa agagatagat
    40681 tactgccaat gtccctattg ggaggaacat aaatattgta agcatacagt tgctgtggaa
    40741 ctttatttac ggtcgaaaaa tctatctcgt atcatgaaaa aagaccagcc aatgctagaa
    40801 ccggtaaaag caacaagtga gggagaaatc attgcaaaag gtttttctcg tctaaaaaca
    40861 caaaacaatc ctcaagcggt gcaacctttg attattgaat accaagtaga aacgattgag
    40921 actaatcagt atcacccaga gctttctatt ttggcacttt acttgcgtat cggttcattg
    40981 gcatcaccga aaaaaacata tatcgtaaaa aacatctatg attttttaca agcttacaca
    41041 gaaaaagaaa cttacactgt taataaacag taccagtttc gtctagataa acgggcgttt
    41101 caaaaagaag atcaaaaaat actcacgcat cttgcaggaa gtgctcagac gcatcaatta
    41161 ttaggtacga acggcttaca agtcaaagga aaactagata aaagatatct gcttctccca
    41221 gtagaacaag cccgcttcct gttagagcag atgaatcaga ctacacgttt gcatctgcag
    41281 ataaatgaac aaaacgatca aggaatacaa ttttccgatc aaaacaaacc tttatcattc
    41341 aaagtggaaa aatttggaga agattatttg ctgcaagcat tgaatgattt tgattttttc
    41401 tttatgcatt atcagtgggg agttatccaa gggacatttt attctctgac gaaatatcaa
    41461 caaacggttt atcaaacttg gaaacaattg attcgccgat tggagaaacc agaagtagtg
    41521 ttcaagaaaa aagaattacc gtctttgttt aaagagatta tccctctgct gtcagagatc
    41581 ggcgacgtag ctattgcccc tgcagtagaa gaggaagtag cagatatccc cgtcgaattt
    41641 attttctttt tccgaaaagc aaaaggaaaa atccaagctc gagtcgattt cgtctatggc
    41701 gaagtcatct attcgactga cccgaagcat gaggtctcga cagaacaggc ttttcaggtg
    41761 ttacgtgaca cagtagaaga gaaacgagta cttgatctat tcagaatgta tcgctaccag
    41821 aaaaatgaaa ctggttatga acgtccattg ccaagcgggg aagaactata tgcctttttc
    41881 cgcacagaac tatctgtctt ccgtcagttt ggtgaagtca gacttggaag aaaattgcga
    41941 gagttgtatt tagatgcgca taaacatcaa ccgaaaatcg aagtaaccga gaccggttca
    42001 tggctcgata ttcgattcga tgtgacaggg atagaggagc aagaaatcga tcatgtcctg
    42061 caaagcttgc tgagaaatga tgctttttat acattagaaa atggtcaggt tctttctttt
    42121 gattcagaag aatttcaaca aacaagccaa gtgttgcaac aattacggga atcgatacgt
    42181 acagaagaag gaacgatcca tgtacctaaa aatcaaggat tgatcattca aaatcaattg
    42241 gaaaaaagca atgctacttt tagtgaatcg ttccaaacga tggtacaaga tctcattcat
    42301 ccagaaagat accaggcaca gcttcccaaa ggattgaatg caacgatgag agattatcaa
    42361 aagcaaggtt ttcgatggtt gaagatgtta ggtcattatc agtttggcgg tattttagcc
    42421 gatgaaatgg gacttgggaa aacactacag acaattgcct ttttactttc ggaaaaagaa
    42481 gaacggaaaa gcttctctgc tttgatcgta gcgcctgcga gcttaattta caactggcag
    42541 gcagaggtga gaaaattcgc cccttcttta agtatccaag taatcaatgg gaataaaaaa
    42601 gaacgtgaag aattactggc taaagacaca gatatccgag tgacttctta tgccagctta
    42661 agacaggatc tagctaatta tcagtcgcaa aaaattgatt atttgattct tgatgaggca
    42721 caaatggtca aaaatagcag tacgaaaact gcacaagcat tgagagaatt agctgtacct
    42781 cagcggtttg cactgagtgg gacaccaatc gagaataatt tagaagaatt gtggtcattg
    42841 tttgcaacga ttatgccagg atttttcccg actaaaacaa aattcaggga acttgccgca
    42901 gaagaaattg cgcaaatgat tcgaccgttt attttacggc gagataaaca aactgtgttg
    42961 aaagacttgc cggaaaaaac agagatgaat ctatattctg cacttacaga agaacaaaaa
    43021 actgtttatt tagcttactt gcgtcaaatg cgtgaagaaa tcacatcaat ggattctgaa
    43081 gcattcaaga aaaaccggat cgggatactt gctggtctga caagactgcg acaaatttgc
    43141 tgcgatcctc gtctgtttat tgaagattac caaggcggtt ccggcaagct cgaacaagta
    43201 aaagatctac tggtagctgc caaagagaac aaacgaagag ttttgctgtt ttctcaattt
    43261 acagggatgc tgactatctt gcaagaagag ttagccgagc tagggatctc gacattttat
    43321 ttaagaggca gtacgaaacc acaagatcgg ttaagtatgg tagacgcatt taatgctggc
    43381 gaaaaagatg tttttctgat ttccttaaag gctgggggaa ctggattgaa tctcacggga
    43441 gcagatacgg tcatcttgta tgacctttgg tggaatcctg ccattgaaga acaagctgct
    43501 ggacgtgcac atcggatcgg acaaaaaaat gtggtagaag tgtggcgtat gatctctgaa
    43561 ggaacgattg aggaacgcat ggattcactc cagcaagaaa aacgcgaact gttccaaaaa
    43621 gtgatccaag gtaatgaaga acagttgacg aaactgactg aagaagacat ccgcatgatt
    43681 ttaagtgtag gagaaatcga ggagtaagag actcgaaaaa gcgttcagta atgggtaaga
    43741 aagcctttct aaagaagcga ttgtttattt gatttaaaaa atagcaagga ggctgggatt
    43801 ccattttatc ccagcttcct tgctatcatt tttttatttc tatttttaaa ggttatacaa
    43861 agattgtctt cattgtctct aacagctgat caaaagaaga aatctcgata tcgcaaattg
    43921 gagtctgttc aattttgcgt tctcgatggt tgaaccaaag cgcttgccag ttagcacttt
    43981 ttgcacctag aacatcattg tcgtaattat cgccaacgta taaggtctct tctggaagca
    44041 tatgaaattc tttctcagct agctgaaaaa tctctttttc tggtttttgg aaacctgttg
    44101 cttgagaaat gagcatattg cgggaaggaa tccaattgtt caattgaagt tgcttcagtt
    44161 tttttgtctg atggtcagtc ggcccatttg tgataattcc taatgggaca ttcttttcct
    44221 tcaagaaatc gagggttttt ttgacctcct catgcaagca gatattatca agttcttcct
    44281 cgtaaatttt ttgaaataag aggccatctt cttccgtaat atgagggtag tctaaatctt
    44341 ttagtgattg gctgatccga tgtgctcgca tatattctag tgtccaatct cctgccatta
    44401 cttttgggaa gttttcatca ctatgatggc ggaaccggat atatagtgga tgcatatctg
    44461 catctgaaac aagcggaacg actcttttga ccgcgtttcg aaatggctgc tgctgatcat
    44521 acatcgtatc atcaacatca aacacaactg atttaatcaa aattttacac gcctttcggt
    44581 tttcattgat tttttcacaa atccttgact attgtaacag aaaaaattgt ctaaaaaagc
    44641 tgataaataa aggtttttct tactatattt ctatttcctt gacagaataa ggtttttata
    44701 tttcagtttt tttcactaaa aatcgtgaaa cacgtcaata agtttgatga acaaattaat
    44761 cattatggta gaagtcgatt gatttatttt aatgcaatct ctgtggaatt ttcgaaagat
    44821 ttattttttt aatacagtct caatataact attcaaacat aaaataacgt tatttgattt
    44881 atttgtttat agtaaatttt atttagtaat cattgcttta aaatactacg cttatataac
    44941 agagaaaata agcgttataa taaagaacag tattatttaa aatgacagaa aacattacta
    45001 ttaaagaaat aaaaaatctt aagaaatcgg tttcatttag cttttgagat aaaataatag
    45061 tacagtttta tacgctgttt catatgttta gaaaatttga attagatttg aaaactctaa
    45121 tttttaaatg ataaaaaaag cgagaatgct ggttttactg tatattaacc ttagataact
    45181 ttcatttttt taaaaaaatt atgaaaaaaa ggtagctatt taaaagttga ttatgtataa
    45241 tagaaacaga tgggagatta ttatgatctt ctgttacaaa aaagtgattc ttatcacgaa
    45301 aaggagtggt gcacgttgtt aacattatat acttccccaa gttgtacttc ctgcagaaag
    45361 gctcgtgcgt ggttgcaaga acatcagatt ccatttgttg aacgtaatat tttttcagaa
    45421 ccattgaaca gttctgaatt aaaagcgatt ttacaaatga cagaagacgg aacagaagaa
    45481 atcatctcga cacgttccaa agtattccaa aaactgaaca tggatttaga tgatctgccg
    45541 ttacaagaat tattggaact tgtgcaaaac aatcctggat tgcttcgccg tccaatcatg
    45601 attgatgata aacgtctgca agttggtttt aatgaagatg aaattcgtcg gttcctaccg
    45661 cgcgatgtac gacaattaga attacgtcaa gcacaattga tggctggatt atagaaggat
    45721 aatacgaaac ttggaaaaga ctattacaaa gatagttttt ccaagttttt ttgtttttac
    45781 aaaaagtatt cttgattaga tgtataaaaa ggtagtagaa gatgatgatt gcacgaaaaa
    45841 tagagaggga aaattagctg aaaagtcggc tatatagtat tcgtctgcca aaaatgttat
    45901 agttaaataa gatagcttga aaggttgaaa aatccgctgg ttttattaaa ttcgcttaac
    45961 agcgagattt tttttcttta catttaagct gatttcgcta caatgaatct atattaaaca
    46021 ttgtggcaaa gtgaggtgta gcaaaatgga aatggaacat attaatgaaa atacgatccg
    46081 tgtactaatt ggtcatgaag atttagagga acggggcgtt tcatttttgg atttacttgg
    46141 caatcacaaa gaaatcgaaa atttctttta tagtattttg gaagaagttg atatcgaaga
    46201 ggagttccga ggaagcgaag ctgtcacttt ccaagttttg ccaaaaggag acggattaga
    46261 actgtttatc agtaaaaatc ttccggatga agaaatttct caatcagaag attctactgt
    46321 tgattcagaa gatgtgagtg actttcttcg tcagcagatt attggcagcg atccggagga
    46381 agaattatct ggaagcgccc tagaagaaca ggaaagacaa gcaacttttg cttttgaaga
    46441 ttttgaacaa gtgatccaac ttgcaacaga tgtcgaacta gagtctgctt ggactgattt
    46501 gtatttattc gaagagcgct attacctagt cgttcacttc tggatggaaa atctcaacca
    46561 agcggatgta gagaatcaga ttgctcgaat tttggagttt gctgaaaaga gcgatcgtac
    46621 accagaaaca ttgaatgaat atggacaatg tctgatggcg cgtaatgcta tcgagcgaac
    46681 gaaattttat tttgtataaa tcagcattat agtaagagac tgtgacaaaa attgtgtcgc
    46741 agtctttttt tcgtataaat gtgttcaaaa gcttgcatct gcggtaacaa gcccaaccaa
    46801 acgaaaaata ttgggaacta tttttgttta gctgttctta ttacttgatg cagaatagct
    46861 ttttcacgcc ctcttttttc gtgtaaataa attcttagac gtaaataagt tcagagggag
    46921 aaaaatgctg cttgcaatga atgaatataa taagtgctgt tttgctaaac atgcagaaaa
    46981 aggaaagaaa tattattgtc gtggctgtcg aaaaagagtg attttgaaaa agggaaagaa
    47041 aaaatgtgct cattttgccc atcaaaaatc agataactgt tcggtcttta gtgaaagaga
    47101 atcaaaagag cacttacagt taaaggaatg cttcatggat tggctgggac agtcagtaga
    47161 accagtattt ttggaagcct atttgccgag gttgcggcaa aggccggata ttttgttggc
    47221 gaatctagca atagaaatcc aatgttctag actgtctcac cagagattta ttgaaagaac
    47281 ccaaaattat ttgaataaca gttaccaagt atggtggata cttggtaatt cttttcttgg
    47341 acaatcgcaa ttctcattga tagaaaaaag ttgctgctac tataatagaa aaagaggagt
    47401 gcattgctgg aaagctgatc tcaagaaaca aaagctttat ttgtatcatc atattacaga
    47461 gactgtatca gggcatattt ccttttgcag tagctgctgg actttttcta gtagggacct
    47521 taaagaaata ttcactagta acgaaattaa aatgaaccaa atgaaaaaaa tagaaaaagt
    47581 gagtgaagat gggaagaaat ggctgacacg ccaacttatt cacaagcaaa agaatacagt
    47641 atccatacaa gaacaatgct acttgcgtca taaacatctt ttgcatctat catcgtggat
    47701 ctatcaaaaa agtcggtttt tcttttattt acaagaacag gtttttcttt atcgaatgtt
    47761 gtacgaagaa gccttggaaa accagaaagt tcctgatttc aactcatggc tttgccaaat
    47821 aaaagaacat aaaagggaat ggctttttcc tatgattgat gaagagatgg tctatcagca
    47881 gttttttaac gaatgcatac acttgtcttc tttgaaaaaa tagtaagtat aaaaataggc
    47941 taggaatcgg ttttctatgt aaaacaagat ttagttatgc taaaattgat ggaagcagac
    48001 acatgaatga gtagaaaagt tagatgctgt gacatgtgga tgttagacta tgatctattt
    48061 tgatagatag agctaaggga agaaaaggag tggatttcat ggaagtaaag cagttgccaa
    48121 aacgagaaga attgcctgaa aatttaactt gggacttgac caagatcttt tcaagcgacc
    48181 aagagtttga tgagaaatat ttggaattat cagaagagtt aaaacaatct gaaaaacaca
    48241 aaggaacact tgatcaaggc gcttctcaat ttttaaatgc gattgaattc gtattgaggg
    48301 tttatcgcca aactgaagtc atttatgtat atgcgcacct taaaaacgat caagacactg
    48361 gaaatacaga ttaccaagcg ctttatgcaa gagcaagcag tctgttttcg aaagttagtg
    48421 aagccgtttc ctggtttgaa ccagaaatat tgcaattgtc agatgaccag atttggcaat
    48481 atttcaaaga agaaccaaaa ttggaagtct atcgccatta tatccagcaa atagtagata
    48541 atcgagccca tgtcttatct gctgagcagg aatctcttct tgctggagca ggtgaaatct
    48601 ttgatgcttc aagtgataca tttgctgttt tgaataatgc agatctagtt tttccaacga
    48661 ttgaaggaga aaatggtgaa atagtccaat tatctcatgg cgtgtatggt cagttgctag
    48721 aaagcacgga tcgaagggtg cgcgaagcag catttaaggg gttgtacagt gtttacgaac
    48781 aatttagaaa tacatttgct tctactttag gcacacatat aaaaggacat aattttaaag
    48841 cgaaagtccg taattacagc tctgccagag aagcgtcttt gagcaataat catattcctg
    48901 aaagtgtata cgatactttg gtagacgtgg taaacaagca tttgcctttg ttacatcgat
    48961 acatggaatt acggaaacgt ttattagaag tggaaaaact gcacatgtat gatctttata
    49021 caccggtctt aggggaagct ccaattacct ttacgtacga agaagcaaaa gaaaaagctt
    49081 tagaagcact gaaaccaatg ggtgaagaat acatggccat cgtagaaaaa gcattctctg
    49141 aacgttggat cgatgttgtc gaaaataaag ggaaacgaag cggtgcttat tcttcgggaa
    49201 gctatgacac aaatccatat attttattga attggcatga tacgctggat cagctattta
    49261 cgcttgtcca cgaaatggga catagtgttc atagttattt cactcgttcg aaccagcctt
    49321 atgtgtacgg cgactactcc atctttttag cagaaattgc ttcgacaacg aatgaaaata
    49381 tcctaacgga gtatttattg gaaacagaaa aagaccctcg tgtacgggct tatgtactca
    49441 accattactt ggatgggttt aaaggaacag ttttccgcca gacacaattc gctgaattcg
    49501 agcatttcat gcatacggaa gatgaaaaag gtgtgccatt gactagtgaa tacctaagtg
    49561 atagttatgg taaattgaat gcaaaatatt atggtccagc agtcgaagaa gacccagaaa
    49621 ttaaattcga atggtcacgg ataccgcatt tttattataa ttactatgtt ttccaatact
    49681 cgactggctt ttctgctgct tcagcactgg cgaagaaaat actaaaccag gaaccagagg
    49741 cactagagaa ctacttggct tacctaaaag caggtaacag cgattatcct gtggaagtaa
    49801 tgaaaaaagc aggagttgat atgacacagg ctgcatatat tgaagatgca atgtcgatgt
    49861 ttgaacaacg tctaaatgaa ttagaagaat tgatcgatcg tttataaggc tttctatttt
    49921 tgattttctc gaatagaaac gaaaaaaata cgtcggctct cttgtaaggg agtcgacgta
    49981 ttttttt
//
LOCUS       DADQDV010000014        48969 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.014, whole genome shotgun sequence.
ACCESSION   DADQDV010000014 DADQDV010000000
VERSION     DADQDV010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 48969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48969
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.014"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(324..1106)
                     /locus_tag="J8S10_000865"
     CDS             complement(324..1106)
                     /locus_tag="J8S10_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629469.1"
                     /translation="MENSSNSAEVNVSTSTSEVVKCSQETTSLPEELLGDWQINNKDA
                     GIEISDSKAVFRIGRSQVESKDYYVDVNNKMLLHVYFSFEYDSVKYIEVSIERTGYSE
                     FISKSVGILTMHTKDGQYISLGVKRVSGENNETEAVTEQTMDERIDSSKSNETEVDTG
                     KTIDERIDSFIETYTAIPPTWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNA
                     VTEQVGKDIPLRLLENGKKDYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(1171..2007)
                     /locus_tag="J8S10_000866"
     CDS             complement(1171..2007)
                     /locus_tag="J8S10_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAZ9629470.1"
                     /translation="MRVIKTLNNSLILCLDKQGKEVILMGKGIGFQLKKGDLVPADKI
                     QKVFKLDSLSDALKKDYIKLFEAAPDDLIICVKRIIDYANAKFDFKLNKSLFFTLVDH
                     LKHAIERSQKGIVFQNRLLIEIQKYYPKEFEIGCYAIQLINKKMNVQLPEEEAGNIAF
                     HIVNAQSEQANMEETMLSVRALKDILAMLGYLFPEKKVDKDSMLYLRFVTHLQFFIAR
                     MIKKEELPEKDDFLLASVKQRFPKEYRAALKIKEYVQEEMGASANQDELLYLTLHISR
                     VY"
     gene            complement(2025..3434)
                     /locus_tag="J8S10_000867"
     CDS             complement(2025..3434)
                     /locus_tag="J8S10_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010757186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAZ9629471.1"
                     /translation="MQYKQLSAFPEKFLWGASISAYQAEGAYQEDGKQPSIIDKYQHT
                     EGVANFEVASDFYHHYKEDIQLFKELGLKAFRFSIAWTRIMDIENNKTNQKGISFYHQ
                     VIDECLNQGIEPIVTMYHFDLPYFLEEQGGWLNRATIDYFVDYVQVLLTEYGDKVNYW
                     LTINEQNTMILHPGAIGLPPSGELPSKKELFQINHHVLLAQARVIHLYHQLNLKGKIG
                     PAINLTAMYQATSSPEDAIAAHNWETLRGWSFLDVAVRGKYNYLFENYLNDRGLYPKI
                     EAEDQAILSSGKPDFIAINYYSTATIAASKNDGSDVSARAGDQQIMLGEEGVYRAAEN
                     PYVDKTPYGWVVDPTGLRLTLRKLYDRYDLPILITENGYGAPDIVEEDRRINDQDRID
                     YLAKHILAIQAALTDGVDVFGYLPWSAIDVVSTHQGFNKRYGFIYVDRTDENLKELKR
                     IKKESFFWYQKVIARNGLA"
     gene            complement(3448..5271)
                     /locus_tag="J8S10_000868"
     CDS             complement(3448..5271)
                     /locus_tag="J8S10_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAZ9629472.1"
                     /translation="MDYREVGRNVLQQVGGKENVVSLTHCATRLRFELKDKRKADTKA
                     LEKTLGVISVVDSGGQYQVVIGNEVQTAFKEIQKEVGTSIKKGPSSDNQESIISRLIS
                     VISTTFTPMIPAITGAGMVKAILAVLTLTGVLSDSSQTYIILNTIADAAFYFMPVLLA
                     YGAAIKFDVNPILAITVAGILLHPNISQLFSTGDAVSFLGIPVLAADYAGSVLPIIFT
                     VWIMSYVEPFADRISPSFIKFFTKPMLVFLIMGPLALVVIGPFGTLLNDLIAMGAEWI
                     NGKAAWLIPFLMGGLQPFLVVTGTAWAMTPIATMQLSSTGSEMINGPGMLASNIAQSG
                     ATFAVAAKTKNKELKQLAVSTGITALMGITEPSLYGVTLKLKKPLVASMIGGAIAGLY
                     AGLSGLVRYAFVSPGLAALPAFIGENPMNIVHAIITCVIAFVATFIIAYLIGFDDTSD
                     ESEQTAIAEAVIVENPVKGTVCPISEVNDAVFSKGLLGKGVAIHPEENSIYSPVEGEV
                     ITILESKHAIGLRSKEGIELLIHVGIDTVNLKGEPFEVFVKAGDQVSAGQLLINADFA
                     AIRNAGYDDTVIVVVTNSENYAGISEASGSLKEHEPLMQIS"
     gene            complement(6114..6440)
                     /locus_tag="J8S10_000869"
     CDS             complement(6114..6440)
                     /locus_tag="J8S10_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629473.1"
                     /translation="MNKVNMNKKFIIIVIVVLAIIGIIFSKMTGTSGLEKSSKPLVTQ
                     ILQEQYNLNRSCDDVTITHENGDNTYRAKAILDNGSAININIEYYPKKDRIYVEIPYA
                     EVLMLN"
     gene            complement(6486..6848)
                     /locus_tag="J8S10_000870"
     CDS             complement(6486..6848)
                     /locus_tag="J8S10_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010717431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HAZ9629474.1"
                     /translation="MYCRKCGKEITDESKYCQFCGALQETDETTGADAVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVALAFIPVVFGAVAVIMGYLYRDKDEQMGTILM
                     IAGVAGAIFGVLLGMSMY"
     gene            complement(6885..7099)
                     /locus_tag="J8S10_000871"
                     /pseudo
     CDS             complement(6885..7099)
                     /locus_tag="J8S10_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            7227..7562
                     /locus_tag="J8S10_000872"
     CDS             7227..7562
                     /locus_tag="J8S10_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAZ9629475.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAEKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVVVDYEEEFLALYRSLSTEDAVRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(7638..9635)
                     /locus_tag="J8S10_000873"
     CDS             complement(7638..9635)
                     /locus_tag="J8S10_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629476.1"
                     /translation="METSMINIPIYVDKEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSFYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFNHKRSNVYRLDVFNATSVIQKLNEDILPLLEKFHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELTNTVC
                     ERLRNVGNNSVENALKENRGYFVKQGFTLERASKDIKRLYNVKASSSFLVYLAKGAGI
                     DEVIKELILSGVELVPLYQFTSVTRDDGRRVRKRKDPIVLN"
     gene            complement(9733..10008)
                     /locus_tag="J8S10_000874"
     CDS             complement(9733..10008)
                     /locus_tag="J8S10_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAZ9629477.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            10240..10974
                     /locus_tag="J8S10_000875"
     CDS             10240..10974
                     /locus_tag="J8S10_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAZ9629478.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            11013..12155
                     /locus_tag="J8S10_000876"
     CDS             11013..12155
                     /locus_tag="J8S10_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAZ9629479.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(12250..13641)
                     /gene="sufB"
                     /locus_tag="J8S10_000877"
     CDS             complement(12250..13641)
                     /gene="sufB"
                     /locus_tag="J8S10_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HAZ9629480.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(13646..14116)
                     /locus_tag="J8S10_000878"
     CDS             complement(13646..14116)
                     /locus_tag="J8S10_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HAZ9629481.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            complement(14103..15338)
                     /locus_tag="J8S10_000879"
     CDS             complement(14103..15338)
                     /locus_tag="J8S10_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAZ9629482.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            complement(15335..16621)
                     /gene="sufD"
                     /locus_tag="J8S10_000880"
     CDS             complement(15335..16621)
                     /gene="sufD"
                     /locus_tag="J8S10_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HAZ9629483.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            complement(16634..17407)
                     /gene="sufC"
                     /locus_tag="J8S10_000881"
     CDS             complement(16634..17407)
                     /gene="sufC"
                     /locus_tag="J8S10_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HAZ9629484.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            complement(17604..18452)
                     /locus_tag="J8S10_000882"
     CDS             complement(17604..18452)
                     /locus_tag="J8S10_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAZ9629485.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            complement(18476..19162)
                     /locus_tag="J8S10_000883"
     CDS             complement(18476..19162)
                     /locus_tag="J8S10_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9629486.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            complement(19155..20189)
                     /locus_tag="J8S10_000884"
     CDS             complement(19155..20189)
                     /locus_tag="J8S10_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAZ9629487.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     gene            complement(20584..20922)
                     /locus_tag="J8S10_000885"
     CDS             complement(20584..20922)
                     /locus_tag="J8S10_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HAZ9629488.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            complement(20924..21280)
                     /locus_tag="J8S10_000886"
     CDS             complement(20924..21280)
                     /locus_tag="J8S10_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HAZ9629489.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            complement(21286..22473)
                     /locus_tag="J8S10_000887"
     CDS             complement(21286..22473)
                     /locus_tag="J8S10_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HAZ9629490.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            complement(22664..23509)
                     /locus_tag="J8S10_000888"
     CDS             complement(22664..23509)
                     /locus_tag="J8S10_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAZ9629491.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            23743..24708
                     /locus_tag="J8S10_000889"
     CDS             23743..24708
                     /locus_tag="J8S10_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HAZ9629492.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            25085..26128
                     /locus_tag="J8S10_000890"
     CDS             25085..26128
                     /locus_tag="J8S10_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HAZ9629493.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(26190..26654)
                     /locus_tag="J8S10_000891"
     CDS             complement(26190..26654)
                     /locus_tag="J8S10_000891"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HAZ9629494.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            26900..27847
                     /locus_tag="J8S10_000892"
     CDS             26900..27847
                     /locus_tag="J8S10_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAZ9629495.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            complement(28058..30130)
                     /locus_tag="J8S10_000893"
     CDS             complement(28058..30130)
                     /locus_tag="J8S10_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAZ9629496.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(30063..30440)
                     /locus_tag="J8S10_000894"
     CDS             complement(30063..30440)
                     /locus_tag="J8S10_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HAZ9629497.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(30569..31129)
                     /locus_tag="J8S10_000895"
     CDS             complement(30569..31129)
                     /locus_tag="J8S10_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAZ9629498.1"
                     /translation="MKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDIKAPSLY
                     NHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSNQAVYEL
                     LISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYLSLRFLG
                     YFTKEPTIDPEDSYFWMINNFIATLP"
     gene            31279..32571
                     /locus_tag="J8S10_000896"
     CDS             31279..32571
                     /locus_tag="J8S10_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAZ9629499.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            complement(32631..33749)
                     /locus_tag="J8S10_000897"
     CDS             complement(32631..33749)
                     /locus_tag="J8S10_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HAZ9629500.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(33763..35184)
                     /gene="arcD"
                     /locus_tag="J8S10_000898"
     CDS             complement(33763..35184)
                     /gene="arcD"
                     /locus_tag="J8S10_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HAZ9629501.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(35430..36551)
                     /gene="mnmA"
                     /locus_tag="J8S10_000899"
     CDS             complement(35430..36551)
                     /gene="mnmA"
                     /locus_tag="J8S10_000899"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HAZ9629502.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            36955..37554
                     /locus_tag="J8S10_000900"
     CDS             36955..37554
                     /locus_tag="J8S10_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphatase"
                     /protein_id="HAZ9629503.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(37692..38978)
                     /gene="efmA"
                     /locus_tag="J8S10_000901"
     CDS             complement(37692..38978)
                     /gene="efmA"
                     /locus_tag="J8S10_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HAZ9629504.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(39249..39593)
                     /locus_tag="J8S10_000902"
     CDS             complement(39249..39593)
                     /locus_tag="J8S10_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HAZ9629505.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(39730..40866)
                     /locus_tag="J8S10_000903"
     CDS             complement(39730..40866)
                     /locus_tag="J8S10_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAZ9629506.1"
                     /translation="MKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGRHAH
                     EKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIEHPA
                     VLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLMPIK
                     EIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKRDGV
                     NIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLILDTL
                     EANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNIEPS
                     HVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(41055..42029)
                     /locus_tag="J8S10_000904"
     CDS             complement(41055..42029)
                     /locus_tag="J8S10_000904"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HAZ9629507.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(42109..42984)
                     /locus_tag="J8S10_000905"
     CDS             complement(42109..42984)
                     /locus_tag="J8S10_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HAZ9629508.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            43114..45021
                     /locus_tag="J8S10_000906"
     CDS             43114..45021
                     /locus_tag="J8S10_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HAZ9629509.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(45562..48840)
                     /locus_tag="J8S10_000907"
     CDS             complement(45562..48840)
                     /locus_tag="J8S10_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HAZ9629510.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
BASE COUNT        14054 a        10299 c         8643 g        15973 t
ORIGIN      
        1 gttatcttta gaaccatttc agatacatat gaaacaatta catatgattt tttcataaaa
       61 aaacagtact gtctagtagt ataaaatata caaatttctt aaaaattttt tcactaaaat
      121 cactacctga aacagtctaa aacacttata tatcaacgtt taatgaaact atctccgttt
      181 catttcagat acaaataaat atagtcgggc tccaaatccg aaaaaaaata cccccagtag
      241 cttatcctaa gctactggag atgtataagt acggtcatat aacaacgggg tagggtaaat
      301 aaatgaaaaa gatggaagaa tcattattca ataacttttt taaatacttc gttgtaatca
      361 gttacctgtc cgttcttaaa taccacagaa taatcttttt tcccattttc aagtaaccga
      421 agtggaatgt ctttaccaac ttgctctgtc actgcattac tgatacctgt tagattagct
      481 aataaatctg ataaagattg agcatctgta gaaatctctg tatcagtatt tatcgtgatt
      541 cctttatctt catttacaag cttccaagta ggtggtatag ctgtgtatgt ttcgatgaat
      601 gaatcaattc tttcatctat cgtcttccca gtatctactt ctgtctcatt actcttagat
      661 gaatcgattc tttcatccat cgtctgctcc gtaactgctt ctgtctcatt attctcaccg
      721 gaaactctct tcacacccaa acttatatat tgtccatctt tagtgtgcat agttaaaatt
      781 cccacgcttt tactaataaa ttcactataa ccagttcttt caatagagac ttcaatgtat
      841 ttcacactat catactcaaa agaaaaatag acatgtaaaa gcattttgtt gtttacatct
      901 acataataat cctttgactc tacttgagac cttcctatac ggaatacagc tttactgtct
      961 gatatctcta taccagcatc cttattatta atctgccaat ctccaagtag ctcttctggc
     1021 aagctagtag tttcttgtga acactttacc acttcactgg tagaggtcga aacattcacc
     1081 tccgcactgt tagaagaatt ttccaaggaa tcaggagcct tagcacaacc aacaagtctt
     1141 tatatattgt gcagccgata ttttcttcat tcagtacacc cttgaaatat gcagtgttag
     1201 ataaagcagt tcgtcctgat ttgctgaggc acccatctct tcttgaacgt actccttgat
     1261 tttcaaggcc gcccgatact ctttcggaaa acgctgcttc actgaagcca gcaaaaaatc
     1321 atccttctcc ggcaactctt ccttcttaat cattcgggca ataaaaaact gtaaatgcgt
     1381 cacaaatctt aagtaaagca tcgaatcttt atcaaccttt ttttcgggaa acagatatcc
     1441 tagcatagcc aagatatcct ttagtgctct taccgagagc atggtttctt ccatatttgc
     1501 ttgttcactt tgggcattta caatgtgaaa cgcaatgttt ccagcctcct cttctggcaa
     1561 ctgaacattc atttttttgt tgatcaattg gatagcatag cagccgatct caaattcttt
     1621 tgggtaatac ttttgaattt caatcagcag gcgattttga aaaacaatgc ctttttgact
     1681 gcgttcaatg gcatgcttca agtgatcaac caaggtaaaa aatagacttt tattcagctt
     1741 aaagtcaaac ttggcgttgg cataatcgat aattcgcttg acgcaaataa ttagatcatc
     1801 cggagcagcc tcaaacagtt taatgtaatc cttttttaga gcatcagaaa gtgaatctaa
     1861 tttaaatact ttttggattt tgtcagccgg aaccaaatcg cctttcttta gttgaaatcc
     1921 aatccctttc cccatcaaaa ttacttcttt gccttgctta tctaagcaaa gaattaaact
     1981 gttgtttaac gttttaatta ctctcattag attcaccgtt ctctctaagc taagccattt
     2041 cttgcgatta ctttttgata ccaaaagaag ctttcttttt ttattcgttt taattcttta
     2101 agattctcat cggttcggtc aacatatata aaaccataac gcttattgaa gccttgatgg
     2161 gtactaacaa catcaatcgc tgaccaaggt aaataaccaa aaacatctac accatctgtt
     2221 aaagctgctt gaatagccag aatatgtttg gctagataat caattcgatc ctggtcatta
     2281 attcgtctat cttcctcaac tatgtcgggt gccccatagc cattttcagt aattaaaata
     2341 ggtaaatcat agcgatcgta caatttcctc aatgttaatc gtagtccagt agggtcaact
     2401 acccagccat atggcgtttt atctacataa ggattttcag ctgcccggta gacaccttct
     2461 tctcccaaca tgatctgttg atcccccgct ctagcggaaa catctgatcc gtcatttttg
     2521 ctggcagcga tggtggcagt tgaataataa ttaatcgcaa taaaatcggg tttaccggag
     2581 gataaaattg cctgatcctc tgcctcaatt ttaggatata atccacgatc attcaaatag
     2641 ttttcaaaca aataattgta ttttccccga actgctacat ctaagaaaga ccagcctctc
     2701 aatgtttccc aattatgggc tgcaattgca tcttctggac tggaggtagc ttgatacata
     2761 gccgttaaat tgattgctgg accgattttt cctttaagat tcaactgatg atacaagtga
     2821 attactctag cttgagctaa taaaacatgg tgattaattt gaaagagttc tttttttgaa
     2881 ggcagctctc cacttggtgg caaaccaatc gctccaggat gaaggatcat cgtgttttgc
     2941 tcattaattg tcagccaata gttcaccttg tcaccatact cagtaagcaa tacctgtaca
     3001 tagtccacaa aataatcgat agttgctcga tttaaccaac cgccctgctc ctctagaaaa
     3061 taaggtaaat cgaaatggta catggtgaca atcggttcga ttccctgatt caggcattca
     3121 tcaattactt gatgataaaa agaaattccc ttttgattgg ttttattatt ttcaatatcc
     3181 ataattcgcg tccaagcgat ggaaaagcga aaagctttta agcctaattc tttaaacagc
     3241 tgtatatctt ctttatagtg atggtaaaaa tccgaggcaa cttcaaaatt agctacccct
     3301 tctgtatgct gatacttgtc aataatagac ggttgtttcc catcctcctg ataggcaccc
     3361 tctgcctggt aggcactaat ggaggcaccc cataaaaact tctctggaaa tgctgaaagc
     3421 tgtttgtatt gcacaaaaat cctctcctta actaatttgc atcaatggtt cgtgttcctt
     3481 taagcttccg cttgcttcac taattcctgc gtaattttca ctgttggtca ctaccacaat
     3541 cactgtatca tcgtagccag cgtttctaat ggcagcgaaa tcggcgttga ttaataattg
     3601 tcctgctgac acctgatctc ctgcttttac aaatacttca aagggttccc cttttaaatt
     3661 cacggtgtcg atccccacat ggatcaataa ttcaatacct tctttagaac gtagaccaat
     3721 cgcatgttta gattctaaaa tagtaatgac ttctccctca acaggtgaat aaatgctgtt
     3781 ttcttctgga tgaatggcta cgccctttcc caatagtccc ttagaaaaga cagcatcgtt
     3841 cacttcagaa ataggacaca cggttccttt taccggattt tcaacaatga ctgcttcggc
     3901 tattgccgtt tgctctgatt catcagaagt atcgtcaaat ccaattagat aagcaatgat
     3961 aaaggttgca acaaaggcga ttacacacgt aataattgcg tgaacaatat tcattggatt
     4021 ttctccaata aaggctggta aggctgctaa gccaggggaa acaaaggcat atctgactaa
     4081 accgctcaag ccagcataca aaccagcaat tgcaccacca atcatggaag caactaatgg
     4141 ttttttcagc ttcaaggtta ctccatagag tgaaggctca gtaattccca ttaaagcagt
     4201 gatcccagtg gacacagcta gctgcttcaa ctctttgttt ttagttttcg cggctacagc
     4261 aaaggtagca cctgattgag caatattaga agccagcatt cctggcccat tgatcatttc
     4321 agaacccgta ctgctcaatt gcatagtagc gattggcgtc attgcccaag ctgtacccgt
     4381 aaccaccaaa aatggctgca aaccacccat caaaaatgga attaaccaag ctgctttgcc
     4441 gttaatccat tcagccccca ttgctataag atcgttcagc aacgttccaa acggtccaat
     4501 gacaaccaac gctaaaggcc ccataattaa aaataccagc atcggcttag taaagaattt
     4561 aataaacgaa ggcgaaattc gatccgcaaa gggctctaca taggacatga tccaaacagt
     4621 aaagataatc ggtaaaactg atcccgcata atctgcagct aataccggaa ttcctagaaa
     4681 agaaacggca tcgccagtag aaaaaagctg tgaaatattt ggatgaagca aaatgccagc
     4741 aacagtaatc gccaaaattg ggttgacatc aaactttatg gctgccccat aggctaatag
     4801 tactggcata aaataaaagg ctgcatcagc aatagtattc aaaatgatgt aagtttgact
     4861 actgtctgat agtacaccag tcaaagtcaa gacggccaaa atggctttta ccatcccggc
     4921 acctgttata gctggaatca tcggtgtaaa ggtggtagaa atgacactaa tcaatcttga
     4981 aataatactt tcttgattgt ctgaagaggg gcccttttta attgaagttc ccacttcctt
     5041 ttgaatttcc ttgaaggctg tttggacttc attgccaatc accacttggt attgtccacc
     5101 gctatccacc acactaatta caccaagtgt tttttctaag gctttcgtat cggctttcct
     5161 tttatctttg agttcaaaac gcagtctggt ggcacaatgg gttaagctga ccacattttc
     5221 ttttccccca acctgttgca atacatttct tcctacttct ctgtaatcca ttattctctc
     5281 tccttaaagc agtaaaaaag accaagtcaa accacgcccc aatcaacatt gaagtgttag
     5341 tttgtcttgg tcttgcctgc ataatcagta acatgccaat aacgttattt tgctgtaatc
     5401 caataatagc acattatgat agcgcaatca acagggaatt taatttttta tcttttcgtt
     5461 tgaccgtata gggtaatata acagttagat cacatcaact agggtatatc tgcgtatact
     5521 tactgctaaa ataagtatat ctaatattaa ctataccagt aaaaccattc ctacataacc
     5581 agcgggaaat tcccaaaatc gtgaaagcat caaaaatgca tataacggat cacacaactt
     5641 caacaattct gctcttggga aaaattgatg aatttggtga gtaaaggatg gaataaacag
     5701 cattccaaca atataggcaa caatagtgat acttgttttt ttggtaaaaa tcagtaagca
     5761 atagccaatt tcaatcattc cgagatataa aggtatcgat agaatgattt gggctagtat
     5821 tcttaaaaat taactagcaa atgtttaaac tgatttattt ctaatctaca tgtagtaagt
     5881 atttcaattc caccaattat caataaaaat accaaacata tccataataa ttttttcttt
     5941 ttcatttctt ttatattgtt ataacagtga ataacataaa aattcccgac aatcattgta
     6001 atattttttt gtcacctgta ttagtattta atttatagga aactataaaa actccctagt
     6061 gaatttacac ctttgggagt tcctgtttgg acggtatgca taatacattt aaatcaattt
     6121 aacattaaca cctcagcata tggtatctcc acatatatac ggtctttctt tggatagtac
     6181 tcaatattta tgttgatagc acttccattg tctaatatag ctttagcccg gtatgtgtta
     6241 tctccatttt catgagtaat cgtcacatca tcacatgatc gatttaagtt gtactgttct
     6301 tgtaaaatct gtgttaccaa tggtttcgat gacttctcta atccagatgt acctgtcatt
     6361 tttgaaaaaa tgatacctat aatagccaag acaacgataa ctataatgat aaacttcttg
     6421 ttcatattta ctttattcaa ctttttatct cctatctcca aaataatttg ctcttatccc
     6481 tcttatcagt acattgacat ccctaaaagt acaccaaaga ttgctccagc tacccctgct
     6541 atcatcaaaa tcgtacccat ttgttcatct ttatctcgat ataagtagcc cataataaca
     6601 gcaacagcac caaatacaac aggaataaat gctaacgcta ctaccataga aatccaacca
     6661 ataatcaaat acagcttccc tgtctcttgt ccatgtacga tttgttcctt catttcatta
     6721 attgtctgct cagtactttt ctttactgcg tctgctccag ttgtctcatc tgtttcttgt
     6781 agtgctccgc aaaactggca atacttactt tcatctgtta tttctttgcc acattttcta
     6841 caatacatgt cttctcctcc taaaaacatt caattgttta ttagttaact gtttacttta
     6901 ttaaatacat cagaaaacag ctcattcatt ggtacactta atatctcaga aagcatcttc
     6961 atttgatagg gtttaggaat cgttctccct gtttgccacg aacttacaca ttgctgtgta
     7021 acattcattt ttttgctaac tccgtttgag aaagtccttt ttcttttctg tatcggctga
     7081 gattacttac ttttttcatg attctcccct cctgttttat tatatacaac aatatgatgt
     7141 atttcaactc ataaaatata aaaaaacttc aaataccatt acaaatacaa caacttgttg
     7201 tactatactg agatgggggt gtattaatga aacagaaaca atatgcaaag gtcattagag
     7261 aaaagcgaaa agctctcggg tggacacaaa aagaattagc tgaaaaaatc ttctctacac
     7321 aacaggcagt agcaagatgg gaaaattctg taacagagcc taacctcgat agcttaaccg
     7381 ctctttctag agccctagga acccctgtaa gccattttct agacaatgtt gtcgtagatt
     7441 atgaggaaga gtttttggct ctctatcgtt ctcttagcac tgaagatgca gttcgaacaa
     7501 ttgactatat gaagctatta aaaaggcaag aaaatgaacg caatcagcta ttgaaagatt
     7561 gaaaaataaa taacccaccg aactttaacg gtgggtgtat tgagatgaaa taagattaag
     7621 agctatggat aacctgtcta gtttaataca attgggtctt ttctcttcct tactctccgt
     7681 ccatcatctc ttgttacact tgtaaattga taaagaggaa ctaattcaac tcctgataat
     7741 atcaattctt ttattacttc atctatccct gctccttttg ctaggtagac taaaaaacta
     7801 ctacttgctt tcacattgta tagtctctta atatccttag aagctcgttc aagagtgaat
     7861 ccttgtttaa caaagtagcc tctgttttct tttaaagcat tttccacgct gttattccca
     7921 acattacgta gacgttcaca aacagtgtta gtaagttctt tctctgtcat tagatatgtt
     7981 ccttgccacg ataagccctg taaaacttca tgtgcttcat ctaaaatcaa ttgtttttcc
     8041 ttgctaagtt ctgatcggga attttgagga aatactcttt tagcctcttt ttcgttaaaa
     8101 catatcttaa cccattcata agaaaaatat tgatatgtaa aatgaaattt ttccagaagt
     8161 ggaaggatat cttcattcaa tttttgaatc acagaagttg cattaaaaac gtctaatcga
     8221 tagacattgc ttctcttatg attaaagttt cctaacgctt tctcttcctt taacctattt
     8281 aggtattcga gcatcttcaa aggaacatct tcatcatcta atttttttat caatcctata
     8341 aaagtcataa gtgatagtaa cttattacat ttatctatgt cataagtttt accatagtaa
     8401 aaactcattt ttttagctaa ttgttccccc gacaaaatac aagtcacact ttccttacta
     8461 tcatcaaaaa aattaacatc agaaagcaag acatcataga cacgtcgcat ttcctctaga
     8521 taattcctta ttgtcctgaa aagtttgtct ttcattgatt caagagtgtc aaaaagtact
     8581 tttgattcct ctttcaattt tcgaaaatgt gtaggataca agtctaggtt ctctaatagc
     8641 caattaaatg tttctacccg actgtctttc tttaaaatta gcatcacaac tccaataaaa
     8701 ttttcactga tatcacaatt actggaatga caataaaaaa tggaatgccc agttttactg
     8761 gtaaaaatac tagcagaggg attatgatcg ttgtgaaaca gacatcttaa gtttttactt
     8821 gacttaagta atttattcat atcaatggtt aacaatcttt cataaatctc attaaaagac
     8881 atgtcggagg aatcaaacag gcagtcttta aaccactgtt tcatttcttc tttgtcgtca
     8941 ttttttatca acttaacaaa atcggtttca ttgactagtt catactctct ccctgaatca
     9001 ctttgacaat ttttagaaca tgtcatggta aaatcaatcg gaagctcagt aatatctaac
     9061 atgttgtctt cattaattat tatcactgca tctgacttat atcctccaaa aaacattcta
     9121 ttcgaagcat ttacattgtc atcacacccg gggatgttct ttttcaagta ttcgtaaaca
     9181 gcaaccattt taccatagtc agtaattgct tcttttaata gaaagacaat cttgtatttt
     9241 tctagatttt cagagtaccg aatacttttt tgtatcgcaa acgcagaatt atgaactaaa
     9301 ttgatagata aaaccttttc tatgcttaag tatctactat catctttact caaatctact
     9361 accttcccct tctcatcttt aacagtgtta tcgacatcca gaataattac tctggtttcc
     9421 acaaaactct ccttgtcatt gcctttattc tttgtcttgc ttggaataaa tgattgtgat
     9481 gaatttagta tctctacaaa ctcatctctt gtaacttctc tatagttatc taaacaccta
     9541 tctcttacat cagttttttc tttttttgta actggcttct ctaataattt ttctttatct
     9601 acataaattg gaatattaat cattgatgtt tccatttgtg tttcctcctt ataaaattct
     9661 gttaaagact aaaacataca gataataaaa acaaactctt tattactata tgttttagtc
     9721 ttatttgttt actcaacctt tataccgttc catgaaacta tcaatatcag attttttaaa
     9781 tctaatgacc gtatcaattt ttataacagg taacccgtat tgagaaacat attttctaat
     9841 cgttcctact gatacaccta gatattcact tgcctgctga tagtccatat actctagagt
     9901 gactccagaa ataatgtctt ctagcatagg ctttagcact gtaattatct ctttcacttg
     9961 ttgttcaact tgtatagaaa caatgctatc aatgatttgt agagacatat ttccccctcc
    10021 tttcgtgatt gcttgaacaa attttctaag aattatcttc gtattttttg ctcaaaataa
    10081 aagtattttg ttattaaccg attaatcaaa caaaaaatga ttaccagttc atcgacatac
    10141 acataatacc tcgataaaaa agaggtgtca atatctttgt aaaatttatt tacaacaccc
    10201 ctttttcgag gtatactaat tttaggaggt gtggtcaata tgataaaacg tccaccaata
    10261 aattatttag aacgaaaaaa gatactcgga acaaaaataa aagctataag aaagagtaaa
    10321 aaattaacac aaccagcatt tggtcttatg attaacaacg gtcaattaat tgacaaaaaa
    10381 actatctacg aatgggagaa gggaacctat ttaccaatac cagagcgatt atcccgaatt
    10441 gctgatttgg gaaatatgag tatagaggag ttagtttgtg gcaatgtaga agaatatatt
    10501 ttgggaatta ttctttatag agatagcatt gtactagatg gtataacatt tccagataaa
    10561 aacctgttcc agcatcttcg tcaacagttc ccaccagtac actctaattt agatacatgg
    10621 ctggatagat attccaaatt agaaccagag atgcaagaat ttattgctaa caagacttgt
    10681 aataaagtta aaaatgaaaa aattagtctt ttcaatatct taaaaataga agaattattc
    10741 atcaatgcta ttgtagaaga atttgacaat aacattcttt tcctcactag cagtatagaa
    10801 gaactactag aaagaatggt agatgaatgg ctacctattc aattgaaaga catgtcttat
    10861 cccgaagaag ctgtgagaga aattactgat aatataaaca agctagaaca aacgatttca
    10921 tcaattggga aaaaatacac taagaaaaaa atgaagggag gtgataccat ctagtggtaa
    10981 gtactccttg taaactaaga ggagatgatt tcatggcaaa aatatcaaag tacaaaaaga
    11041 aaaacggtca agtggcgtgg atgtataaag gacacattgc caccgatcca cgaactggtg
    11101 aaaaaataaa tactacgaga agaggtttta gtagcaaaca agaagctcaa aaagattatg
    11161 acgagtacag acatcaaata ttatacggtg ttaaaaagaa agcacctgat atgacatttg
    11221 aagacctgta taatgaatgg ataactcatc agcgtaccag tgttaaagct tcaacaatcg
    11281 caatctcagt aagatacgca aataatcaaa tacttccagc atttggtaag cttaaactat
    11341 cgaatatctc tgtcccatat tgtcaaaaag tggtagatga atggcacagt aaatatgaaa
    11401 gttacgatta tatgagaaaa cagactgcac aaattttacg ctacggggtt gcaatgcaat
    11461 atattgacaa taatcctatg gaaaaaacac ttcttccacg aaaaaaagag tatgagaaaa
    11521 atcgtaaatt ttactcaaaa gaggagctta ataatttact ggatgctttt aaagattttg
    11581 gtaacatgaa acaatacgcc ttcttcagat tattggcata cacaggtatg agaaagagtg
    11641 aagtactcgc tttacagtgg aaagacatag acacgtttaa taaagaacta catgtcaata
    11701 aaactcttgc tgtagatgaa tttggtaaag ttataattca atctccgaaa acaagagctt
    11761 ctagacgagt tatctcttta gatactgaga ctctttctat cctcaacaac tggaaattac
    11821 agcaaaaaga agagtattta aaacttggat acaatactag ctctaaagag caacatgttt
    11881 ttacaacagt taaaaacact ctatacattc caaacactgt taatgattgg ttaagatata
    11941 ttttgaaaaa atataacttg cctcgtatta cacctcatgg gtttagacat acacatgcta
    12001 gtttattatt agaagcagga gaatctgtca aggtagttca acaacgatta gggcatgaaa
    12061 atagtaaagt gacattagac atctatgcac atattacaaa taatgcacct aagaaaacag
    12121 gtcaagactt tgctgatatg atggctcatc agtaaaagag ctggtcaaaa tctggtcatt
    12181 tctagtatac aggcaaaaca aaaaagctag aacccttata tatcaagggt tctagctcct
    12241 ataacaggtt tacccaacac tgccttccat ctcataactg atcaatcgat tgagttcgac
    12301 tgcatattcc attggaagtt ctttggtgaa tggttcaaca aagcccatga cgatcatttc
    12361 agttgcttca gattcggtca ggcctcggct catcagatag tagagttgtt cttctgagat
    12421 ttttgagact ttggcttcgt gttctaaaga gacttggctg ttgtggatct cattgaatgg
    12481 gatcgtatcg gatttcgacc attcgtccat gatgatcgtg tcacattcga tatgagagat
    12541 cgaacccgca ctgtttttgg caaaggttac ttgtcctcga tagtttactt ctccgccgtc
    12601 ttttgaaatt gatttagaga cgatagagct agatgtattt ggtgcattgt ggatcatttt
    12661 tgcacccgta tcttggattt ggtttgctcc tgcaaaggcg atggagagca tggtgcctcg
    12721 tgcacctttt ccatctaagt aaacacttgg gtatttcatc gttgtttttg cacctaggtt
    12781 tccgtcgatc cattcaacgg ttgcgccttc gtatgctttt gctcgtttgg ttactaagtt
    12841 gtacacattg tctgaccagt tttggatcgt tgtgtaacgg caatacgcat cttttcttgt
    12901 aaagatttct acgatggcgg catgcaggct gttacttgaa taagtaggtg ccgtacaacc
    12961 ttcgacatag tggatgcttg ctccttcgtc aacaatgatc agcgtacgtt cgaattgccc
    13021 cgtgttttcc gcattgatcc ggaagtacgt ttgtaatgga acatcgactt tgacgccttt
    13081 tggcacgtaa ataaaggtcc cacctgacca tacggctgaa ttcagcgctg ctaatttgtt
    13141 gtcggttggc ggtacaagtt ttgaaaagta ctctttgaat aattcagggt attctttcaa
    13201 agcagagtca gtgtcagtaa agacgattcc taacttttcg aattcatctt tcatattatg
    13261 gtacacgact tctgattcat attgtgcgga agcaccggct agataagctc gttcagcttc
    13321 tggtatacca atcttttcaa atgtatcttt gattttttct ggtacgtctt cccagtcacg
    13381 agcgggtttg tcacttggtt tttggtaata tttgatggca tcgaaatcga tgtctgaaag
    13441 gtcggggccc catgtttgca ttggcatttt gttaaatgtt tctagagatt tcagacggaa
    13501 ttcaagcatc cattctggtt cgcctttgat tcttgacatc tcacggatca cttcttctgt
    13561 caagccttct cctgtactga aaaccggttc gacatcatcg tgaaacccga atttatattc
    13621 ttctaattct ggtacgccca tgttctcact cctcttcctt gtggtaatga tggaaagctg
    13681 cggtaccatc gttttccatt gcttttccta gtgctttcca ggcaagtgtc gcacatttga
    13741 tccgagcggg aaatttagct acaccaccaa gcatagcagc atcgcctaat tggtcgggat
    13801 ctttgacttc ttttccttgg acaagctgta gaaagtctac agttaaatgt tctgcttctt
    13861 ctattgattt tccgatgacg gcgtctgtca tcatcgaggc acttgccgta ctgatggagc
    13921 agccactgcc gtcaaaggcg atatttttga tgattccgtc ttttacatcg acttgcaatt
    13981 cgatcacatc tccacatgtg gggttgttca attcgatctt gcttgtcgag tcagtcaagc
    14041 ttccacgatg atgcggatgg gaagaatgat ccaagatcac ttgacggtat aaattgtcta
    14101 atttagatag tcccatgttg gaaaaactcc tttgttgcca tgattgcttc aactaaacgg
    14161 tcggcgtctt gcgttgtgtt gtagaaataa aagctcgcgc gagcagtcgc tgatacttca
    14221 aggtacttca atagcggttg cgcacaatga tgacctgctc tgacggctac cccttccatg
    14281 tctaaagctg tcgcgacatc atggggatgt aacccatcca aattgaatgc aacgactcct
    14341 gtccgaaaat tcgggtcttg tggaccataa acagtcaatc catcaattgc ttgtaatttt
    14401 ggcaacacat aagcggctag ttcttcttca tatcgatgga tattgtccat accgagtttt
    14461 tgcaaataat cgattgcatg gcctaatgcg atagcgccgg cgatatttgg tgtccctgct
    14521 tcgaatttcc aaggtagttc tttccatgta ctgtcgtata attcgacaaa atcgatcatt
    14581 tcgccaccaa attcaacagg ttccatttct tctaaccatt ttcgtttacc atataaaaca
    14641 ccaatacctg ttggtccgca cattttgtgt ccgctgaaag caaagaaatc acagtctagt
    14701 gcttggacat caatggccat gtgcggggca gattgagcac catctactac gatgaccccg
    14761 ccgttttcat ggacaagttc agctaattct tgaacaggat tgaagacacc taagacattg
    14821 gatacatgag caatggagac gattttggtt ttgtccgtaa tctttttcgc tgcatcctcc
    14881 atatccagga agccttcttc tgttagttcg atatatttca agacagcacc tgttcgtttt
    14941 gccaactgct gccacgggat aacattagaa tgatgttcca tgtaagagag cactatctcg
    15001 tctcctgctt tgatatagcg gtcgccgaag gttctggcta cccaattcaa gcttgtcgtc
    15061 gtaccacgag taaacagcac ttctgctgtt tcttttgcat ggatgaacgc ccgtactttt
    15121 tctcttgctt gttcataatc atgggtcgcg cgttctgcta acgtatggac accgcgatga
    15181 acattggcgt tatcgtgttc gtaatagtac gctaatgcct ggagtacttg ttttggcttt
    15241 tgggtcgtcg ctgcattatc cagataaact aaaggttcat cattgacgtc ttgaaataag
    15301 ataggaaaat cattgcgtag ctttttagca tcgatcatcc attcaacttc ccttcgatta
    15361 cttcgactaa ttctttccga acttgttcta cagggattgc tgttaagaca gaaccgagga
    15421 atcctcgaat cactaagcgc tctgcttctt ctttatgcaa tcctctactc atcagatagt
    15481 acatttcttc tggatcaact cgtcctacac tggcagcatg tccagcagtt acttcgtttt
    15541 catcgatcaa aagaatagga ttcgcatcac cacgtgcttt atcagaaagc atcaagacac
    15601 gactttcttg ttgggcatct gcaccttttg cccctttcaa gatgtggccg ataccattaa
    15661 aggtcaatgt tcctttttct cggatcactc cgtgttgcaa aatatgcccg atcgtatgag
    15721 gggctttatt ggttactcgt gtatcgattc cttggatttg tctgcccgag ctgattgcca
    15781 cgattttgac ttctgcgtgt gcaccttctc ctgctaaatc tgagtcaaag tcagcgatca
    15841 catgaccgtc attcatgaca ccaattgccc agtcgacaga agcatctcgt aaaatgtgcc
    15901 cacggcgatt catataagaa gtaatatttt ctcctaattg atctacggct gaatatttga
    15961 tttttgaacc agctttagcg atgacttcca cgatgatatt acctgatgat tttgctactt
    16021 gttctttggt tgtctggaaa cgttccagat aagaaaattc actatgttca tctgccacga
    16081 tcaacacatg cttgaagaag tgctcatcgg atgcgccatc ttgaatgaat aaggactcga
    16141 gtggttcatc gatcacgaca tttttaggca catacaggaa aataccgctg ttcataaaag
    16201 ctacatggag tgcagtcaat tggtcttcgt tcatgtttac tgcttttttc atataatatt
    16261 cttggactag ttctggatat tcgatcattg cagtgaacaa gtcggtaaaa atgactcctt
    16321 tttctgctaa ttccacaggc agttgttcaa aaatcgtcca tgaaccttgt tggacaagca
    16381 caggattgtc tttcattgca tcaaatgccg gaatcgtgcc tgtttcactg atggtttgtg
    16441 tttctttcac atcaaataac gaccagcgat ggaatttcac ccgatcgata tgcggcaatg
    16501 gcagttcatc tgctttcgct agtgcgtctt gacggaaggt tctcatccaa tcaggttcgc
    16561 ctttacttaa agaaaaatca tttaccgcgt caagataatc gagccagttt ttttctttca
    16621 ttcttgctcc cccttacgct tcttcttctt tatagtcgat tcctaattct ttactgatac
    16681 cagcgtagcc ttctgcttcc agacgtttag ctaggtcagc attccctgtc atgactactc
    16741 ggccttccat catgatgtga acgacatcag gtgtgatata gttcaataat cgttgatagt
    16801 gggtgatgat caatgcaccg aaattgtctc cgcgcatttc atttactcct ttagcaacga
    16861 ctttcaaagc atcgatatcc agacctgaat cgatttcgtc taaaattgca aatgtaggtt
    16921 ctaacatcaa caattgcagg atctcattcc gtttcttttc tccgccagaa aaaccttcgt
    16981 tcagataacg ttcagccatt tcttctggca tatttagtaa agccattttt tcatctaact
    17041 ttttcaaaaa tgccataaca gaaattttgt cgttttcatc acgtttcgca ttgatcgctg
    17101 cacgcatgaa ttccgcattc gtgatacctg gtatctcact tggatattgc atagctaaaa
    17161 ataagccaag tcgcgcacgt tcatctactt ccaagtctaa aacatttttc ccgtcaaaca
    17221 aaatttcgcc ttctgttact tcatagtttg gattgcccat gatagcggca gataaggtag
    17281 attttcctgt gccgttaggt cccatgatgg catggatttc tccggttttc attgttaggt
    17341 ttacgccttt aaggatttct ttttcctcga tcgacacatg tagatttttt atttctaaga
    17401 cagacatgca ttataccccc aaattctctt tcgttctcac tcattttaga ctaattgaga
    17461 atgaagcgca atgaccttcc ttactaaaat caaatatctt ttatttatta ttaaacaatt
    17521 ttgatttcta aattagaata ggtataaaaa agatgagaaa taagccatta cagacttatt
    17581 tctcatcttt tttgttccat accttatttt gcatcagcct ttactggttt aacagagccg
    17641 ccccatttgt ctgtgatcca ttcttggact tctttgcggt gaagcacttc aatcagtttt
    17701 ttgattttgt cactgtcttc atcaccttta cgagtcgcaa taatattcac gtaaggagag
    17761 ttgtcctttt caagcaatac ggcatcttct aatggattca accctgcgcc gtaagcgaag
    17821 tttgcgttga ttgcaactag gtcaccttca tcattttggt acgtagaagc taaaagtgat
    17881 gggtcgatcg tatggttgaa cttcaagttc ttagggtttt cttcaatatc atcgaatgtt
    17941 gctgtttcca gatctactcc atctttgact ttgactaagc cagcatcttg tagaattgtg
    18001 atgatgcgtc cccagtctga ttcagaattt gaagtaatga ttgttgcacc atcttttaat
    18061 tcggaaacat ctttgacttt tttagagtac aagcccattg gttcgatgtg gacagcaccg
    18121 gcattgacaa agtcatatcc tttttctttg atttctttgt tcaaataagg aatatgctgg
    18181 aagtaattgg catcaatgtc gccttcttcc aaagattggt tcggtaatac atagtcatcg
    18241 aatttgacga tttcaagatc gattccttca tctttcaata atggtttcac atgttccaaa
    18301 atctctgcgt gcggtgtcgg tgaagcgccg actttcaatg tcgtgtcgtc tgctttattt
    18361 gctgaatctt tgctgtcgct gttgttaccg catgctgcta atcctacagt cagcaaaagc
    18421 gctgctgcaa atccaaaaat tttctttttc atatcctaca tccccctata tcctattatc
    18481 ttttgtctgt tttcttagtt aagaaatcac cgattccttg aacgataaat acgattagta
    18541 aaataattaa agtcgcaacg aatgtcactg ttagattacc acgctggtag ccttcctgcc
    18601 aagcaagacc tccaagtcca cctgcgccga tcgcgccggc catcgcagta aatccgatca
    18661 tcgagatcgt tgtaactgtt aatccagaaa tcaatgcggg aatactttca ggtatcaaga
    18721 ccttccagat gatttcccag taacttgctc ccattgcatc tgctgcttcc agtacaccag
    18781 ggctgacttc acgaaaagca atctctacta gacgggcata aaatggtgct gcggataaaa
    18841 caagagctgg aatggctgct tgcgcaccta gcatagtgcc tacgattgct ttagtaaatg
    18901 gaatgatcaa aaccatcagg atcataaatg gcgttgaccg gaaaatatta ctgatgatcg
    18961 atacgattcc ataaatgatt cgagcatacg gtttgttttt gcgtccaata gagtaaagga
    19021 tcaatcccaa aactaatccg atgatcgtca ctaagaccat tgagattaat gtcatatata
    19081 gtgtatcaag gatagcctga ttcatcgttt ccgggttgat ttgtttaaaa tctagatatg
    19141 tttctgaaaa gcttttatcc acgatggatc acctcaattc ctactccttg ttctttgatg
    19201 aacacttctg cttgatctaa ttctttggtt tcaccagtca tcaagacagt caatgaacca
    19261 aaggaacctt ctttcacttg tttgatcttt ccatacacaa cgttgacatc gatgttatag
    19321 cgtcgaatcg cttgggaaat gactggctcg ttggcatttc tttcgctaaa ggtcaaagtt
    19381 gccaaacggc cgcttggatt ttctttgatg agttcagcta atagttctgt cgaatcagct
    19441 tctggttcga tgtcttgttg tacaaagcgt ttggttactt cttttttcgg ttgtctgaag
    19501 acagtcaata cgtctccttc ttctacgact ttccccaact ccatcacagc gactttgttg
    19561 cagattttgc ggatcacatt catttcatgt gtgatcaaga cgatggtcaa attcaatttc
    19621 ttattgatcg ctaacaataa gtctaatact tcttctgttg tttgcgggtc caatgcgcta
    19681 gtagcctcat cacaaagcag gatctcagga tcatttgcca atgctcgtgc gataccgacg
    19741 cgttgtttct gtccgccgga aagttgtgaa ggatatgctt gtccgcgtcc ttctaacccg
    19801 actaaacgca acagttcttc tgcccgttct ttacgtttgc tctttggtac gccagctaat
    19861 tccagcggca gctggatatt ttcaagtaca gttcttgacc ataacaggtt gaaatgctgg
    19921 aagatcatac cgattttctt tcggaatgta cgtaattctt tgttttttaa ttttgtaata
    19981 tcttgatcgt ttacgatcac ttcgccgctc gtgggaagct caagtccatt caggagacgg
    20041 actaatgtac tttttcctgc gccagaatag ccgacgattc cataaatatc ccctttttca
    20101 acgtttagtg aaacgtcatt gacggcttgg atgtttccgt ttttcccatt gaatgtcttt
    20161 ttgacattcg ttagttggat taatgacatg ccattcacat ctttctctta taatttttca
    20221 aacaaaaaag ccttcgccct cttgccttaa gcaaaaggac gaaagcttga acttccgtgt
    20281 taccaccttg atttaccgtt acttcgcaat aacagcctct tccagtactt ggacttagct
    20341 tctttccgta tactgtcgcg ctgtaacggg cactcccgta gtaagtttgc ttacgctcgc
    20401 ttactctgct ctaagaccat cttccatctc attttcgtta cccattttca gcaaacaggg
    20461 ctctcttcaa acgtccgtga catgtactct tcttttcaaa gctttctcgt ttcatatagg
    20521 attgcttatg attatagcaa ctggaagaat cagtgtcaac ttttttcaag tgattttctg
    20581 attttataat tcgtcaaatt cttttggatc aacatctttg aaacttaaga tccacgcatt
    20641 catttcatct gaatcattca agatattgat atcttcaccg attttatcat taacagaaga
    20701 aactgtaccc gttagcgggc tggcaaattc attgaccgct ttttccgctt caacttcgat
    20761 cagaggttca tcttttttta gcgattgtcc tgcttttggc agattggcaa acgtgatgtc
    20821 tccaagttct tcttgcgctt catttgtcaa accaacacag tattcttttc cattaaataa
    20881 gatccaaagg ttgtcctttt tcttcaaatg cttgcctgcc attttatatc agttctcctt
    20941 cataaatttt ttcattgaat ccaattgcaa caagctggtc ctctcgtaag atcagtggtc
    21001 gcttgatcag cataccatct gtcgataaga cttggctcgc ttttgaagcc gtaaactcgc
    21061 ctacttgatc tttcagtcca agttcccgat atttcatccc gcttgtgttg aacaggcgac
    21121 ggattggtac ttgactcgtt tctagccaag tctcaatcgt tgaggccttc ggtacttctt
    21181 tgatcatatc aacggtttga taactaacgc catgctggtc taaccacgct ttggcttttt
    21241 tgcatgttga acatttcggg taccagtaaa aggtgtacaa ttttcttacc tccttgaaga
    21301 tcttgcaggt gcttcatttt ggtatctcat cgataatatc aacccgatac cgatcatgtt
    21361 ccctaaaatc gaggatcctc cctgactaat gaaaggcaat gggatccctg ttaaaggaag
    21421 taatccgata tttgctccaa tattctcaaa gacatggaac agcagcatca tgatcaaacc
    21481 gcttgcgata taggcgtaaa attcattatt cgtatcgaaa cacacccgaa tcatacgata
    21541 gattaaaata aaatacaaga aaatgacgaa tgcaccaccg ataaagccga agttttcacc
    21601 gataacggta aaaatcatat cggactcacg aacaggcaca tagatattgc ttacgttgaa
    21661 tcctttacca aacaagccac cggtaccaat tgccaaaagt ccttgggccg gctgataact
    21721 cattcctgac gtatcatgga aagggtccag ccatgaatca atacgtgcaa actgataaga
    21781 tttgaatcca actttataaa gcaagtctct tccgccttca gtcgtaacca agaagatcgt
    21841 tcctgctcca acgactactg ccaagattac tacaggtgcg atgatgcgcc aagagattcc
    21901 agacatcagg aaaatcccgc caaagatcgc aagaaagaca agcatcgttc caaagtcatc
    21961 ttgggccatg atcaatgcta aaaccggtat tgtcacgatc aagagcttcc caatcagcca
    22021 aaagtccgat ttcatcgtcc gttcttttac ttgcgtatta tgtttagtta cgatcagtgc
    22081 catcatcaag atgtacgcaa tcttcatcaa ctctgctggc tggaaagtaa acgcaccgaa
    22141 tcgaaaccag tttttagacc ctgttgaagc agctaaattc tgatcataga atttgagcaa
    22201 gagtcccatt accactaacc ccaaaccata aaggtaagga gtcagtttcc agatccattt
    22261 ggaattcaaa tgcatgatga caacgattgc tgccgctcca actaaatacc agacaacttg
    22321 catccctacg cctttcaaga ctgctggatt gttcggatca tggctaagtg ctacatataa
    22381 tgagagcaga ccaatcaaac ataacagaaa gactggtaaa atcacgccat aatcaatacg
    22441 attatcgttc gaagctttta attttttttc catgtttcat cccttttctt aaaaaccata
    22501 ctgctgatta ttatagcggt ccagttagat aatggaaagt ctttccatag acatttggga
    22561 aaaattaact ttccgtttgt gcagttgctt gagcaaatgc agtacaaaag cctactgctt
    22621 atctttagtg tatcatagaa ctttttttga tacatgcaat tatctaccag ctgagattct
    22681 cctcgctgtg agaagtttct gtgctttcat tgtatcgaag gatctcttcg gcaatctcta
    22741 gcagctgatc agaaaccaga ttggttcgtt ggatgaaata aaaatatcga tggaaattca
    22801 acggagtcat tggcacattt tctggaacag agcgcttaga caaaatcgag cgaccgattc
    22861 cttccttcag caacgcaaca attacatcgt tacttttcac gatcatcttc ttatcttgga
    22921 tattcatctc ttcaaaataa cgctgcgtgt aatgaaaaac accagagttt gcttctctta
    22981 caagccacaa tttgcttttt gggtccccag cgatgactag ctggtcttcc atcaaagagt
    23041 atctttgtac gccggaagtc tctaatggct tttcgataaa accaaaatcg gattcatgtt
    23101 tcgctacttg ttctaatgat tcatgagaat tcgtgatttc gatctcaaaa tgcactttag
    23161 gaaacctttt gatcagatgt ttcatcaact gaggcaaaag atagacagca aaggtgtggg
    23221 aagcaacgat ccgacatact tcttcttcat tttgttcatt gagcaatttt tgctgagttt
    23281 cttcccattc ttctaacaaa accagtgtcc gttcatataa taagtcggct tgcttagttg
    23341 gaagcatctc ttttcttccg ttacgttgaa aaagatcgat attcaattcc cgctccaact
    23401 gtttgatttg attcgagact gctggttgag ataaaaacag tacttctgct gctctggaaa
    23461 aatttcttgt ttcatatact gctcgaaaag tcgttaataa cttaaacatg gcaccacttc
    23521 cataactttt tatgataatt actataaaaa ctatttgatt taaatataca aaaaaccatc
    23581 tataatagaa atgtacaaca aaacagttgc tgatccaact agtaacttag atgaagacaa
    23641 tcagctgtct gcttgctcgt aatcatacat tcctattcat tttacaatgt attcgttcat
    23701 cttggtacta aaatctatta aataaaaagg agaatattat atatgaagaa ctttttgaaa
    23761 attattccga tcccgatctg cgggttgatc cttgggttag cttcccttgg aaatctgttt
    23821 aaagactatc accatgttgc tttaggcaat ctaactggcg gtatctctat gattcttatg
    23881 atattcattt ttgttaaatt gtttatctta ttcgaacaca cgaaacaaac gttgcatgat
    23941 ccaatcatcg cctccgtttc accaactttt acgatgtcac tcatggttat ttgtacttat
    24001 tttgtttcat atgaaagtat tgcaccaatt gtcaaattca tttggctgtg cgctgttatc
    24061 ttccaagtga tccttgtctt ttatttcaat tatcaccatg ttatcaaagc tgatctttca
    24121 attgaagcaa tttatccaag ctggtttatc atttacgttg gatttggggt catcactgta
    24181 actgccggga acttcttccc acttattgga aaaattttct tttggatttc attgatctgc
    24241 tatgcgttct tattgccgat catcatcaaa cgtgtctttt tcgtaagaaa tatggctcat
    24301 ccgacacgtc cgctgattac gatcgttgca gcacctggtt ctctttgcct aacaggttat
    24361 cttaaaaact ttgctgaacc taatttttat cttgtcgtag cattgttcgc tttatctcaa
    24421 gtattgtatt tcgttgtgct gtctatgctt ccacgtttgt tcaagcttcg tttttatcca
    24481 agctatgcag cctttacatt cccgcttgtt atctctgcaa cagctatatt tactactgtt
    24541 cattacttca acagtttagg tatctatagt agcgtattgg atttcttaaa agttgcggaa
    24601 tgtctgtttg caagtgtagt tgtcttctac gttcttgctc attacgtacg tttcttaatt
    24661 aaagaacata gcaaacatgg aaaatttgtt tctaaaaaaa tcgcttaata atcgattcaa
    24721 taggttgtga aaaagctgtt ctgcatcaag taataagaac ggccaaacaa aaacagctgt
    24781 tcatgttttt gtactggttg ggcttattac cgcagatgca agcttttgaa caccgtttac
    24841 caagaggtcg taaaagaagt ggtcagcttc aagaaataag aaggaattta cgaaaattgc
    24901 ttctcaaatt tttgtgaaat ttcggcttat ttccgtagaa gctacttctg gaacaccgtt
    24961 tattcgaaac aagaggtcgt acaagacttt tgtcacgacc tcttgttctt ttgtcaaaat
    25021 actggtttag tgctactatg ttcgagtatg cttttagtat ttattgacga aaggaaccga
    25081 tcaaatgaaa tcattgtcac atccaataaa atctgtaaag gattcagcgg tccgcgaaat
    25141 cttacccggt ttactgcttt cttttgccat cgctgccttc agcaggcttc ttgctattta
    25201 tctgccacag ttaggtggag cgactattgc tattttattg ggtattttat taggaaatac
    25261 tttttttaaa cagcctgttc tagcaatcgg cacaaaattt gctgaaagca aactattaga
    25321 attctctgtt tttttactag gtgcaactgt cacagctcaa acgattgctc aaattggtgt
    25381 aaaaggaatt gtttttgtgt tactgcaaat gtcagtcact atcatcggtg cttacttgat
    25441 tggtaaaaaa ctgcaattca gcgatacttc ttctttgatg atggctggag gaaacgctgt
    25501 ttgtggttct tctgctattg cttcaatcgc cccttccatc catgcgaaag aggaagaaaa
    25561 aggacagatc atcacactag tcaatctact gggtactgtg atgatgttga ctctcccttt
    25621 tcttggatta cagttgtttg gtggaaatct cattgaaaaa agtgcacttt tgggtggtac
    25681 actccaatct gttggtcaag tagtcgctgg ggcaagctta cttgacaatt ctgttgtcga
    25741 attcgccatg ctatttaaga ttctacgtat tatgatgctc gttgttgttg tctatctgtt
    25801 tgaaaaattc atgcacaaga aacaaccagc tctgtttgaa acgccaactg atacgcagaa
    25861 aaaacgaaaa ttaccgcttc cttggtatgt attagggttt gtgatctttt gtttggtcaa
    25921 cagcttgttt tctttacctg tagttattga ccaatcggca cattttatca gcagctggtt
    25981 tgagatcact gctttagcgg caattggtct gcgtttagac tttgcaaaat tcatgaaaga
    26041 aggtacacgc ttcttatctt atggattagc tgtcgggctt ctccaaacag tgatggcttt
    26101 actatttatt tggctgatca aagtttagaa tgaacatgaa aaaacagttg tgattctcgc
    26161 atggaacaat gtccgaatca caactgtttt taattttgca gatatccttc taacaacaac
    26221 aattggcgtt tgatttcaac cccatctatt gcgtttccca tatatcctgt cagttttcca
    26281 ttttgcccga tcactcgatg acaaggaata acgattggca atggattggt tcgatttgcc
    26341 tgcccaatcg ctcgcacagc tttcggacta tcaacagcaa cggctacttc tttatacgtt
    26401 cggatttctc cataaggaat ggtcgacaaa gctttccaga cattttgctg aaaaggcgta
    26461 cctctcttta tagataaagg aacatcaaat tcttttcttt ttcccgcaaa atattcttca
    26521 aactgttctt gtgtgcgcgt taaaattcgc tgattcgctg attcgctttc tgaaattggc
    26581 tgaaaagata cagcagtcaa tccggattca tctgcatcta accataaaaa gccgataggt
    26641 gtgtgtattt tcattttgtt tgctcctagt caatagactg gaacttcctc ctttttctct
    26701 atccaaaact acttgccaac taataaaaat tgttcttaaa agtttgataa accgaggaaa
    26761 catggtaaac taaatacgtt agtttacaaa aagaatacct gttcttttac gtaaaatcaa
    26821 attttaaagg tgttatttaa ggtttattaa attttgaatg taaaccatat ataaacatac
    26881 gattgaaagg atagaaacga tgaaagtatc aattgttgtc ccatgtttta atgaagaaaa
    26941 aactgttcct cttttttttg atgaggttga aaaattcaaa ggtgcccatg agttcgaata
    27001 tttgtttatt gacgacggat caaaagacgg tacgttagca gcaatcaaga agctagcctc
    27061 agcttatcct tatgtccgct ttgtctcatt ttccagaaat tttgggaaag aagcggctct
    27121 gtacgctgga ttgcaagctt ctacaggaga tttagtgacc gtgatggatg ttgatctgca
    27181 agatccgccc gaactgcttc ctgagatgat caaccggatc actacttctg atatcgattg
    27241 tgtcggcacc cggcgttcga ctcgtgaagg cgagcctgcg atacgcagtt tctttgcgaa
    27301 aaaattctac cagttgatca ataaaatcag cgatacagaa atggtcgatg gcgctcgtga
    27361 tttccgcttg atgactcgtc aaatggtgga tgccgtccta gaattaacag aatacaaccg
    27421 attttcaaaa ggattattta gctgggtcgg atttaaaaca gaatatattt cttatgaaaa
    27481 ccgcgaacgt gtggctggcg aaacatcttg gtccttctgg aaattattca actactcgat
    27541 tgatggtatc gtgaacttct cggatgcacc gttaacgatt gcttcattta tcggcgcttt
    27601 gtcttgtgtc ggttctggta ttgcaatttt gttcattatt ttgcgggcat tgttgtttgg
    27661 tgatcctaca tcaggatggc cttccatggt ctcgatcttc ctgttcattg gtggaatcca
    27721 attgttatgt cttggaatca tcgggaaata tattgggaaa atcttcttag aaacgaaaca
    27781 gcgtcctgtt tatatcataa gagaaacaga aaaagtgaag ccaaatgaat tgaagcctca
    27841 ccaataatat acgtcaaatg aagtaaacat ttttttaaat gaaaaaggac tgtgacaaaa
    27901 gtcttgtcac agtccttttt tccgaataaa tggtgttcca gaagtagctt cttcggaaat
    27961 aagccgaaat ttcacaaaaa tttgagaagc aattttcgta aattccttct tatttcttga
    28021 agctgaccac ttctatcaca acctctttca tatcttatta cttcttcatt gctgctttta
    28081 gtgctgctgc taatgggctt tcttctggtt cttctgcttg tgcatatttt ttcagcaagc
    28141 gtcgttcttc atgtttggtc attttcttct tctgctcttt tttatcaagc aatttttctg
    28201 tcgttccatc gtatttacaa cggaaataag caccgttttt accttcgatg atttccattt
    28261 tccggtgaca ttgcgggcat cgatgattag agacttttgg atcttttctt ctgcggtagt
    28321 tgcaatctga attggtgcag acatagattt tgccgtcacg tgtgtttttc tcgcgcagat
    28381 tggccccaca ttctgggcat ttcttttggg taatcgagaa atcttgatat tcttgtttgc
    28441 ttgatttgat ctcattcacc aagcgttttg tttctttttc gattccattc aagaaggttc
    28501 ctgcttgttt ctttcctgca gcaatagctt caaggtcttt ttcccagctt tctgtcaaat
    28561 ctggtgttac taaagaggga tttaccaata ctaataattg cttaccttta ggagatactt
    28621 gcagtccttg aggggtacgt tccatcagtt cagatttgat tagtttctcg ataatctctg
    28681 cacgcgtagc tggggttccc agactgtatt tttccatttg accaagcaag cttgcttctg
    28741 acaatggttt aggcggtgca gatagttctt ttttgatggc gaaatcggga ttgattctca
    28801 ttcctttttc ccatttgact gtttccgtct cagtttcagt ttcgcctttc catcctgctt
    28861 ggacgacacg attttgccga aaaatgaatc gttctttacc aaattcaacc gtaacttttg
    28921 tttggctgac tttatggggt tgagcaaaca gtcctaaaaa acgagagaca atcatttgat
    28981 agatttttcg ctcttcatta cttaattttt cataacgtgc tctgttttca gttggcaaaa
    29041 gtgcatggtg atcggtcact ttactgtctt ggaatacttt tgtctgttgg acgatggctc
    29101 cgtttttcaa atactgcttg acctcaggag caaagtcgct gactgcttgc aatcgttctt
    29161 tcatcgtact tttcatgtca tttgtcagat atttgctgtc tgtacgcgga taagtaacga
    29221 tcttatgggt ctcatacaaa ctttgtacaa gacttaatgt tttctttgca gaatagccat
    29281 agcgttgatt ggcttctctt tggatctctg ttaaatcata aggcaatggc gcagattccg
    29341 tttttaattt ttcttggact tctgtgacag ttcctttgct tgtactgatc aattgaacaa
    29401 gtttttgtgc ttcttcttgt gtttttaaag caaattgatt tttttgaagc attttggctt
    29461 gttcttttcc agcttgcaac gtgatcgtga aatacgtttg tggacggaac tgctcgattt
    29521 tcttttcttg gtctctcact aatgctagtg tcggtgtctg cacacggcct gctgataaat
    29581 tatccgcgta cttcacagtt aaggctctgg tcacattcaa tcctaccagc cagtccgctt
    29641 ttgcccgggc aagagcagat tcatacaatg catcatattc tttcgcaggt cttagttgct
    29701 tgaatccagt tttgattgct ttatctgttt gagaagagat ccataaccgc ttcactggtt
    29761 tattgaaatg cacatactct aagatccagc gagcaacaag ttccccttct cttccggcat
    29821 ctgtcgcaat gactgcttct gagacatctt ttcgctgagc cagctgcttg attgctttta
    29881 attgatgtcc tgttttagga agtggtttga ttcctagttt tttagggatc attggcaacg
    29941 tgtccatttg ccagctctgc cattccttat tcagatcttc cggcattttc aatcctaata
    30001 aatgaccaag ggcccaagta acgatcacct tgggtccttc ataataattt ttgtgctttt
    30061 gattagcacc aagcaccttg cttaggtctt tcgcaacgct tggtttttcc gctagaatta
    30121 gttgtttcat aaaattcctt tctgctttct actgtgatgg gctgatgatt tttcaacaac
    30181 gcaagtccct tgtattgctg taaatcatcg tcacactctt cacaccagcg ctcatctccg
    30241 tcattccaaa aggcgctgag aaagttactt tttgcattga tatattcata attttgatgg
    30301 atttcgttcc attgtttttc gtacgcttgt cgtgcttctt cgaaagactc gaatgtttct
    30361 tcttcttcaa tatcttcttc ccagtcttca aaaaaccacc aaggctcatt gtccccgaac
    30421 atggtaatta cttgatacat actcgtgctc cttctttcag cttttctaga ctcatcttag
    30481 tcacttttca agaaagttgc aagaattttc tcttataaaa gggtcattta atgaacatct
    30541 taaaattgtt acaaatgaat ctgattgttt aaggcaaagt agcgataaag ttattgatca
    30601 tccaaaaata gctgtcttct ggatcgattg ttggttcttt tgtaaagtat cctaaaaaac
    30661 gtaaggaaag ataaccgtgg atcatactac gaagttccct gcttcgatga actttttctt
    30721 ctttcgttaa ttgaaaagcc tcaaatatct gcaaaatgat ctgattcgtt tcatggattc
    30781 catctaataa aacagcttca ttggtatgcg gtacactgat cagtaactca tacactgctt
    30841 gatttgaaaa agcaaaggat cgataagttt ctgcatagat ctgcagtgct tcctgaccac
    30901 tttttcccac aagagcccgt cgcagctggt cattaagttc ctgcagaagt ttcgctgtta
    30961 gcgctgtttt gacatcacga atatttttga aatggttata cagcgaggga gccttgatat
    31021 ccaagcgttt ggctaaatgc tgaaaggtta tttgctgaac atccatctct tctgctagtt
    31081 ctcgaaagca gtcgatgatt ttctcttgag acagatttct ttttttcatt tccatgtttc
    31141 ctctcataaa ataaatcctt cactctttca gtttaccacg aaaaagaaag agaaaaaaga
    31201 gactttcatt gataaactac atattgtagt ttataataaa gagctgtaga tgaaaatttt
    31261 cagaaagaag gagtctaatt ggctgcaaga ataaaggaaa aattatttag gaaaagagaa
    31321 acttgggaac aaaacttgtt tgtcttatgg tttggaacat ttatggctgg tatcggattt
    31381 agtttagtca tgccttttat gtcactttac atagatacgt taggtaatta tagtacgtca
    31441 caattgaact tttggagcgg attgactttt tcatctactt tcttggtgac tacgcttatc
    31501 tctccttggt ggggaaaatt agccgaccaa aaaggaagaa aattgatgct gttgcgtgct
    31561 tcattaggaa tggcaatcgt catttctttg atgggttgcg tgactagtgt gtatcaatta
    31621 gtcgcattgc gtctgcttca agggattttt tctggttata tcagtaatgc cactgccctt
    31681 gtcgcaactg ggacgccaaa agaaaaaagt ggtcaagttc ttggaacctt agcaactggt
    31741 tctgttacag gaacattact tggaccgctt cttggcggga tctctgcttc agcgtttggc
    31801 tatcgcccta cctttttcat tacagggatc atcttatttt tcgtcttctt gttgagtctg
    31861 tttttcgtcc atgaaaaatt tgtcccagtg aaaaaagaaa acatggtttc tgccaaacag
    31921 attttcaaag acttgaaata tccacacgtc gtcatcggta tgttcgtcac aacgatgatc
    31981 atccaagcat ccaacaattc cattagtcca atcatcagtc tgtacattcg ccaattgctg
    32041 catggacatg ggaatgttac gttgatcagc ggaatcattg cttcgatacc tgggattgcc
    32101 actttgatag ccgctccaag atttggtcgc ttaggtgaca agattgggag tgaaagaata
    32161 cttgcgattg gtttgggttt tgcgattctg gtttatatcc caatggcatt cgtcacgaat
    32221 gtttggcaat tagctgcctt acgttttttg attggtatct ctgatgcttg tctgctccct
    32281 gctgtccaag cattgatcac aaaatattcg cctcatcaag ctgctggacg gatcttcagt
    32341 tataaccaat ctttccaagc aactggtaac gtagtagggc ctatgatcgg ctccagtgtt
    32401 tccagtgcat ttggttatcg cggcgtcttt ctttcgactt ctcttcttgt tttggtcaac
    32461 ttcttgcttg tacgacacaa tacacaagag atccatcagc aagaaactgc agaagaaaaa
    32521 gcttcaggag tctccatagc ttcagggcac tctccttctc atagacaata agcgtaaatg
    32581 aaaaacactg cttgaacagt tgtcacagac tgtccttgca gtgtttttgt ttaggcctgt
    32641 tttttcaaga actcagataa gaggaataat cccttttcca aggtttcttt tttacaacag
    32701 taacctagtc gggcatgctt cggtaaatca aaggcacttc ctggtactaa tagtactcct
    32761 gtttcttcta ataaattgat acaaaatgtc tggtcatctt cttcgatggc taatttaatg
    32821 aaagaagtag agacgtaatt gggagcgaca agttcaactt tcggttcatt ggctacccat
    32881 tgttttaaaa tcacaaggtt ctctgtaatg atctttttgt ttcgcgccaa tattttttct
    32941 ttattcttca atgcatgtac agcaagatca tctgacagga ctccgccgca aatcatcgtg
    33001 tagtctcgat actttcgaaa aacttctgcc aactcaggtc cagtagctgt ccagccaata
    33061 cgaatacctg gaatggagta ggttttggat agggaattgg ttgctatacc tttttcatag
    33121 acatctacga tcgacaagaa ttcaccttta tccgttaaag gcgcatatac ttcatctatc
    33181 aatacatatg catctactgt acgagcaatt tctgcgattt tttctaaagt tttccgatct
    33241 agcaatgtgc ctgtaggatt gtttgcacta ttcaaacaga tgatttttgt ttcaggtttg
    33301 actaaggctt ctagctgttc taaatcaaac tgccaatctt cttcttcctt caaatgaaca
    33361 aagtcaacag cggcacctaa agatttgggg atgtcatata attgctgata agtaggaagc
    33421 atcgaaacaa catggtctcc tgcttccact aacgcgtata gagctaaaag attagcacca
    33481 gtcgctccat tcgtttgtaa gatgttttcc ggatcgacgg tttgataaag agaagcgact
    33541 tcttgtttga aaacatctga tccttcgatc cagccatagt ccaatggttc gtttttgcgt
    33601 ttttcgaaaa atttacttac gctagtccca tctaagccaa cgagttcgtc taatgtcaat
    33661 gcttcgatcg agctttgtgc aatatcatat accgctttct tttcccattt atttagccat
    33721 tcttctacac cgaaatttgc gattttcatg tttctttccc ccttatatct tgatccagcc
    33781 tacagcaagc aacccgattg aaagcagtgc ggccacacaa atcagcccaa tcattacttt
    33841 ttcttttccc gtaatttgat gtttggtttc acgacaagcg atccagtaga agcaaaaacc
    33901 aggaagatag gcaatactac ataaaaggac ataagaaaat cctgctaaaa tgatgcccat
    33961 caattcaaaa actacagcaa tcccaccgat cactacttgt tttttgattc cttcttttaa
    34021 agaaaactgg acttgataga tcccgacaag tagataacaa atcaaaattg ccgctgtaca
    34081 taaagaatag gcaaattgat aggcataatc agtaactaag aaagtcaata agaatagatt
    34141 agtcaagatt gcagtaacaa ctaacgaata agttggggca ttttttttat tcgtttttcc
    34201 ccaacctttc ggcaacagac cgtctcgagc catcaacatc gttgtttctg ctgggagcat
    34261 cgtccaagac aaccaagaac caatgatcga aataatcaag ccgatattga tcagcgctgc
    34321 tccccaattt cccacgattc cttttaaaat atttgccata gcaggttgtg aaatagttgc
    34381 taactcttct tgagataaga cgccgtatgg caagatcgaa gcaaggatat agataaacaa
    34441 taaacaaagc agaccaatga tcgatgcttg ctgggcttct gaacgtttct tcgcgcggtt
    34501 ggctaaaaca cttgcgcctt cgatccctac aaagacccac atcataacca tcaaacaacc
    34561 tttaatctgc aaccagatcg ttccttgctg ccctgttcca ttcactagat tatcagatac
    34621 gttaccccaa aaatcagcag tgaatatatt cactttaaat gcgataaata caaatattaa
    34681 aaataggaat aatggcacta atttacagat cgtcacgatt gtattgatga cgctcgctcc
    34741 ttcaactcca ttgtttacta ataaagtcag accccaaata aaaatacttg caaataaaat
    34801 agaaggaaca ttttgtccac ctttgaatat cgggaaaaat tctcccatgg cgctcatcag
    34861 catcgttgca aaagcaacat ttcccagcca cgcagacaac cagtaacccc aaccactgat
    34921 gaagccacct aatttaccaa atgaagcttc cgcgtaaccg aaaataccac catctagatc
    34981 tggacgcttt tctcctaaat gattcagcga taataccaaa gctaaaatac caatcccaac
    35041 gattatccat gaaaggatcg ctggccctgg agctgcagaa ctagccagat cacttgtgat
    35101 cccaaacaca ccgcttccga ttgacgaact gacaaccaga gcaaccagtc cccatttgct
    35161 aatacccgtc gatttctttt ccatttccat caccctcact tataaaattg aacaaatcac
    35221 ttgcaaaaga ttcccttcta ttttgcaact gctcttgctt aacaaaaagc aactttattc
    35281 atattattgg atattatgaa ctttttacac aagtatttca agtataaaat gaataaaaat
    35341 taattttatt gcaaaaaaac agctatgcta tccaaaagaa aaggtgtttc ttttgttagc
    35401 catagctgtt ttgattcatt taatatcgct taaacgtatt gtaaaacttt tgtttcttga
    35461 tatgcgtggt cgatcaaacc accacccaga cattccattc catcataaaa tacaactgct
    35521 tgtccaggag tgattgcacg tacaggttcg tcgaatacga cttctgcacg attatcatcc
    35581 aataagcgaa ctgtcacagg aacgtcttgc tgacgataac ggaatttcgc tgtacacttg
    35641 aattcttttg gcattggttc attcgtcgta aagtggattt cacttgcatc caagcttgtg
    35701 gcatacaatg caggatgatg gaacccttgc cccacatata atgtgtttgt cgctagatct
    35761 tttcctacaa caaaccaggg ttcttgcgaa tctcctccgc caccgatccc tagtccttga
    35821 cgttgaccaa tcgtataata catcaagcca gcatgttgtc ctttgacttc accatcaaga
    35881 gtgaccatat ttcctttttt tgctggcaga tagttgctca aaaattgttt gaagttcttt
    35941 tcaccaataa agcagattcc cgttgaatct tttttcttag cagtcgcaag gcctgcgcgt
    36001 tcagcaattg cccgtacttc tgatttttcc atgccgccta gagggaacat cgtttttgaa
    36061 agctgttctt gtgataattg gctaaggaag taagtttgat ctttattatt gtctactcca
    36121 cgaagcatgt ggaccacgcc gttttcatcg cgagtgactt gcgcataatg tccagtagct
    36181 acataatcgg cgccaagatc cattgcataa tccaagaatg ctttgaattt gatttctttg
    36241 ttgcacatca cgtctgggtt aggtgtacgt cctgcgcggt attcggctag gaaatattca
    36301 aatacacgat cccaatattc tttttcaaaa ttcacagagt aataaggaat cccgatttga
    36361 gcagctactt tcgctacatc cttataatct tccgtggccg tgcatacacc gttttcgtcc
    36421 gtgtcatccc aatttttcat gaatattccg atcacgtcgt atccttgttc ctttaacaaa
    36481 agtgctgtta cagatgagtc gacaccgccg ctcatcccta cgacaacgcg tgttttgctg
    36541 ttgtctgtca tgatatcacc atcatttcaa ttagattctg aaacatctac gagttgaagg
    36601 tcgcaacttt tcagtatttt acattatacg tcatatttct gaaaatttca tcccttaatt
    36661 atcaagtcgt aaaaatactg ttctactgga cctattcagt acacaaacat gatagtcaac
    36721 caaaaaatca ctcatctttt gagcattcga tataaaaaat tggcatactc ataaaaaggg
    36781 ccagcctttc ggcaataagg aataatttta taaattgtga aaaactattt ttcaaaattg
    36841 cttcttatcg cttaaagctg cacgtctcat ttacaacctt ttctttttag atgttatgag
    36901 ttgctcagat aagtgatttt gtttactcta agaaaaaagg gaggcaaaag atacatgaat
    36961 tactttatca gtgatatgca ctttttccat gaacgcttat taggaaaaaa cgactttgct
    37021 ccgcggctct ttgcaaatgt ggatgaaatg aaccaacagt tgatcactag ctggaatgca
    37081 gtaataaaag aaaccgacca tgtttatcat ctaggcgacc ttgctatgca tccgcaatat
    37141 gaaaaagcaa atgcagaaat tttggaactg gtcactcaac tgcaaggaac aatccacttg
    37201 atcaaaggga accatgacag tcgcgctttt ttccgttatt tagaaaaaaa tgatcctagg
    37261 cttactgacg gaagtcccaa attttatttt tatgatgtag gtgccatcgt taaattcgac
    37321 catcaacaat attacttgac tcattatccg atgttgctcg ggcctaacga cactatccgc
    37381 aatcttcatg gacatatcca tcattacagc gtacctatcg agaacgatgt caatgtaggc
    37441 gtagacgcac cggaaagaga actcttaaag gaaaaactac catttggcac tccgttatct
    37501 gagcaacaaa tcaaagaaat ctatgaagca aagaggaagt acgataggtc gtgaaaaaac
    37561 tgccctatat caagtattaa acaaataaag ataattactc atatttttca tttgagtagg
    37621 cttattgcca caggaacatt aggatcagaa atggagttgt aacaagactt ctgtcacaac
    37681 tccattccat actattcgtc tttttgctca tggtgttctt ttaccagttt tttctgtaat
    37741 tctttatcat aatttcgggc agctgacgtt aaaaataaaa cgattccgca taataaaatc
    37801 ccgattccgg aaaacaagaa cattttttct acccctaaac gatcagctaa tggtcctgca
    37861 aataataatc caattggacc tgccaggttc atcaaagagt tgaagttccc taagacacga
    37921 cctaaaacat tcgattcata actctgctgg atcattgcca tcagcagtgt attgaaatat
    37981 ggcgttgcac aacctgctcc tgcattcaag ataagaaagt acaagaaccc ttgactatcg
    38041 tttggaacca atccgcttgc accgatcgtc aggcccataa tgatgtaggc tataataata
    38101 ggtttcattc ggtctttcca tgttcctata aaactgatca gtgcaccgcc taagagcatt
    38161 ccgactgcgt agactacttc cactgctccc gcctgtccaa cggaaccacc aaagtaatct
    38221 agcgtcatca atggatacag actgattgct ggcatgaaca acagcatcac aaatgcacca
    38281 ttgatcgtta tgtaccataa ccctttatta tccatcaatt gctgcagccc aaattttgca
    38341 tctttaaaaa tagtaagcgg aacttccaat atttcaggag aaacttttgg gatcttcaca
    38401 aaaatcaata agccgacacc aaaaactgcc cccaatacat ctaataaaat aaggtaattg
    38461 acaggaacga ctgaaaacaa agccgcacct agagctggcg caatgatgaa attcgctgat
    38521 tggaccattc ctaactgtcc attcgtcctt gttatgtgag aagatggaac gattgtcggc
    38581 ataatcgact ggatcgttgg catttggaat gtttgtgcga ccgaacgcat aaacaaagac
    38641 acaaaaacta gccaaatcgg gaaggattct gaaatcgttc cgactactgc taaaataagc
    38701 gcgaaaatcg ctacaataat atccgtgaca atcaaaagag cttttttatc ccagcgatcc
    38761 actagcggtc ctacaaatgg gcttagtaaa accatgggaa tcattcctag taaagtagca
    38821 aaactcaaaa ttgtcgccga accggtttct cttgtcaaat accagatgat cgcatattgg
    38881 acgaccatac tagtgattcc tgacaaaaac tgtcccgata aaaagaacaa ataatttctc
    38941 ttccaattcg ttaaaacgac cgactgttca ttttccataa acatccctct tttctttttc
    39001 attttgtata gcgtttgcac aacaatcatt atacgggatt cttttttcaa aaaatacctt
    39061 tttccctaaa taacaatcgt ttcaatttaa atttctttac ttagaaacaa taaatcagca
    39121 aaatattaaa aataacaaca tgtgttaaat ttaaaaataa aaaagacaac taatttgcgt
    39181 cgtccttaca aagttagtca tctaacaata ggccgtttca aaactagttg tctttttata
    39241 tccacagatc attcgacttt ttcgaataac ccacggctaa tcatcccatc catcagaaaa
    39301 taaaatttat cttggctcat tttctgtttt ggatctttga aaatattgac tgctttcaat
    39361 ccatttgctg tagtgatcga cattttcaat gtttgaatat cttttgatac agtgattttt
    39421 aatttgaatc cttctttgct ttgcggcgtg gcatctaatg gtcggatcaa ttgataattg
    39481 cctccgtttg tttctgtaaa tccattatcg cgcaatgtat atctttttgc atcaggatgc
    39541 aaacgatagc taattggtgc gcccagtacc gttgctgttg tttcaaatgc catgattttc
    39601 acctcgataa aattagtttc tctttattat aaaagtttat cctgattttt actaggtttt
    39661 tcagttaagt tccctaaaaa atgaaggcgt tctctcagac atctgttcat ataagaatga
    39721 cttcactagt tattttttga cagcacgaac taattgatca aggaaatact ggatgtcgtc
    39781 ttcggtattt cccaaaccaa agctgatacg gatggattct tttagtatcg gtgtatcttc
    39841 tccatacatt gcttctaata cgtgtgaagg ctcgatattt cctgctgtac aagctgaacc
    39901 agtagaaata gcgaccccat taagatcaag cttcatcagt agcaaatcat ttgcttcgcc
    39961 aattaagcga agattcaaca catgagggag tttattcgtt aaatcaccat ttacttgata
    40021 agggatttcg tttgcttcta atgtatcaag aatcaattgc tggaatcctt tatatttgtt
    40081 gttacgtgct tcacgttctt caggtgacag cagttcaact gcttttgcca taccccagat
    40141 ccctgctaaa ttttctgtac ctgcacgccg cttttcttcc tgctccccgc ctaaaagcaa
    40201 tgcagggata tttactccgt ctcgtttata taagaaaccg acgccttttg gcccattgat
    40261 tttatgagca gagatactta ataaatcgat tcctaattct tctggatgga tcgtttggtt
    40321 tccgtacgct tgtaccgcat ctgtatggaa ataagctgga tgatccgcta aaagttcacc
    40381 gatttctttg attggcatca aatttccgat ttcattgttc ccgtacatca cagagaccaa
    40441 gatcgtatct tctcgtaacg cttttttgac ctcttcgatc gacagattcc ctttttcatc
    40501 tacaggcaga tatgtaacgt caaacccctt tgtctctaaa tatttcatgg tattaagaac
    40561 agcaggatgt tcgatagctg tagtgattag atgtctgcct tctttttgac gcgagaacgc
    40621 tgtttctaag atagctgtat tatccccttc tgttccccca ctgttaaaga tgatctcgtg
    40681 aggttttgct tgcagactgt ctgcaatgat ttgtcttgct gtttccaatt tttcatgcgc
    40741 gtggcgacca aatccatgta tgcttgaagg atttccaaac gtgtcttgca tgattgccgt
    40801 catcgcttca attacttgtg gatgcatggg ggtagttgcc gcatgatcca gataaatagt
    40861 tttcacttca ttcatccctt ccaaattatt gctaggcaca ttctagcata aaatagcgaa
    40921 caaaccaaag aagagctcat ttttgtctag aggacgtttc atgggcatag aaaaaaggag
    40981 ctgtgacaaa agtcttgtcg cagctccttg aagctgctca cttctgtcac aacttctttc
    41041 cctctttttt ttgtttattc gaattctttt tcttccagac ggaataacgg actcatcggt
    41101 gtattttcat ggatgcgttt gaccgcttca cccattaatt ctgaacatgt aacgattgtt
    41161 aagttttctg gatgacgatt ttcttctgtg aaaacagaat cagtgataca aatatctttg
    41221 attggtgcat tgtctaaaat acttttcgca tgatcggaca ataatccatg tgacgcacag
    41281 gcatatactt cttttgcgcc gttttctttt aatacatttg ctgctcgtgc aagcgttgct
    41341 cctgtgttca agatatcatc taccatgata catgtctttc cttgaacatc accgatcaca
    41401 taaccaccct cagttgaagc atcatctgca tgatctacga tggctaatgt gctgttcaaa
    41461 tattctgaaa gactacgtgc acgctgaaca ccgctgtttt ttggcgaaac aactacgatg
    41521 tcatctcccg tcagacctaa ttgacggtaa taatgagcaa acaacggcat cgtaaataaa
    41581 ttatctacag gaatatcaaa gaatccttgt acttgaaccg tgtgcagatc taaagtcagt
    41641 actcgagttg cccctgcttc ttcgatcaag ttagcgatca atttcgcagt gatcggttca
    41701 tgaggtttcg ccgtgcggtc ttgcctagca tacccatagt aaggcaatac gacattgatc
    41761 gttttcgcac ttgctcgctt cattgcatcg atcatgatca gtagttccat atagtaatca
    41821 ttgacaggtg cattcgttga ttgaacgata tacacatgat cccctcgaat actttcttcg
    41881 atattgatgg aaatctcgcc atcactaaat tgcttcacga cgcttttacc taattctgtt
    41941 ccgaacactt tcgcgatttt ttcagctaat ggacggttgc cattcaaact aaaaatcttc
    42001 aacgtgtcat cctgatactt attactcatg tagtcctccc caaaacttct ctattcttcg
    42061 atagtttaac atatttttcc aagattttct gttaatttca gcaaattctt aaggaagtga
    42121 aactgttccg ttactccaac tggcaggaat gactttatga taatcgcccc agttgtcgtg
    42181 tactttgtaa taacgttctc ctgtttcagt ttcaaaataa gcgtacgctg tcacccaatg
    42241 attgccatat gtactgccaa gtactttcaa aataccaatc atcacaggtt tgccttcacg
    42301 tatacgtttt gtagctcgct gccatgaacc tagaagagtt gctcgtgcac gctcatgatt
    42361 gccattcttc tttaaaaaac tagaaatccc tgtactaacc tgaaaaggaa tcgtaggaag
    42421 tcctagtggt tggatctggc tacgcaatgc cttcgtcaaa accaacgaat cagccgtatt
    42481 tttcttgcga atctcatttg gaagcatcca ccccttacga tagtcttgat aataggcaag
    42541 gagaactgct gccgcgtaag taccacaaag atagcctgag ggggtagccc atttcttata
    42601 cctcaaaaaa cgttcttctg gcaatcccac ccagcaattt gcgagttcct ttcctgacct
    42661 tttttcttcg atcaaaacgg gaatatcttc ttttctgttg atccatctag ataactcgat
    42721 tggctcttca ttgatcagct tccatttttt acaagaaaga ccctcttgat aagtatattt
    42781 tgctggagaa tattctaccg gatgtcctga ttgatcgata atcacataac tttgatcttc
    42841 aaaaaccaga gctaaaaaaa gcaatttact ttttcttgac tgcagctgct gagtgctggc
    42901 taatttttta atttttttat ctactttgaa atataaaggt ttatccacta cttgattcag
    42961 ttgggatcgc ctcctttttt tcattataag tgaaggattg aaaaaaacaa atcagtttga
    43021 ttgttcgaat tttcaatttt ttatgttcta tttgttaatt ccttcatttt gtaagataat
    43081 gggcacacga aacaaaaaag gagcgatcga tgaatgaaca aagaacgatt gaaacaagat
    43141 ttctatgaag cagtcaatga agaatggcaa aaaacagcaa aaatccctgc agataaacca
    43201 gctacaggcg gtttccaaga tttagttgac gggatcgacc aacttttgat gggagaaaca
    43261 gacgatctgc ttgcccatcc agaaaaagtg tcttcagaaa aaatgaaaca tttccttgca
    43321 tattatcaac tggcaaacga ttatgaccga agaaatgagt tgcatgctca accgcttcaa
    43381 cctataatcg aaaaagttga atcattgcag tctttcgacg aattgaataa gcaatttcca
    43441 gaatggctgt tggatacatt accattgcca tttaatctgg atgtagatgc agatatgaag
    43501 aatgcgcaaa cgaacgcctt ctttgcttat ccgccttctt tattccttcc agataagacg
    43561 tattatgcat cagaccatcc caacggtgca caactaatag gcgttttctt tgatatggct
    43621 gttcagttat tagagcttgc cggcaaagaa aaaagtcagg cagaagcaat cacggaacaa
    43681 gcagtgcaat ttgataaatt gattgctcct catgtaaaaa gtgcagaaga aaacgcagat
    43741 tacagcaaaa tgtataatcc gcaatctttt gatacattta ttaaatacac agataaactg
    43801 gacttgaaaa aacttgtcac gggtttgatt gggacaactc cagataaagt gatcgtaact
    43861 gatccagtgt acttcgatca tttgaatgac atcctgacag aagctcattt tccgttattc
    43921 aaaagctgga tgatcattaa aacagtacgt tctcttagtg gttatctatc agaagaattc
    43981 cgccaagtca gcggaatcta ttctcgcgta ttgtctggaa cagacgaagc aatgcctcag
    44041 aaaaaagcag cgtattacct tgcctctgga caattcgatc aagtagttgg cgattactac
    44101 ggaaaaaaat attttggcga agctgctaaa aaagacgtag aacaaatggt gaaaaaaatg
    44161 atcgccgttt ataaaaaacg tctagaagaa aatgactggc ttggggatgc aacaaaagaa
    44221 aaagccgtca taaaattaaa taacttaggt atccaagtag gctaccccga taagatccca
    44281 gcattattcg accagttcaa aacagtacct gcagatcagg gtggtacttt gctttcaaat
    44341 actcttgttt tcagcaaact cacattaaaa gatcgtttca gcaaatggaa caaaccagtg
    44401 gatcgttcag aatgggaaat gagtgctgac acggtcaatg cttattatca tccatttcgg
    44461 aatgtgatcg tctttccggc agcgatcctt caagcaccat tttacagtct agaacaatca
    44521 agctctgcta attatggtgg aatcggagct gttatcgctc atgagatttc ccatgcattt
    44581 gataataacg gcgctttatt tgacgaatat ggcaacttga acaactggtg gacagaagaa
    44641 gatcttacac aatttcaaaa caaagcacaa gcaatgatcg aagaattcga tggtctgcct
    44701 tttgctgacg gaaaagtaaa cggaaaatta accgtttcgg aaaatattgc tgatgcaggc
    44761 ggtctaagct gtgcattgga agcagcaaaa acggaatcag atctttctat cgaggaattc
    44821 tttgtcaatt gggcaacgat ttggcgtaca aaagcaaaaa aagaatacca acaactttta
    44881 ctgcaaatcg atgtccatgc ccctgctaaa ctccgagcaa acgtgcaacc aaaaaacctt
    44941 gacgaattct atgaaacatt tggtatcacg gaacaagacg ctatgtatct agcgccagaa
    45001 aaaagagtgc gaatctggta agaggttgtg ccagaagtgg tcagcttcaa gaaataagaa
    45061 ggaatttggg aaaatcgctt ctcaaatttt tgtgacattt cggcttattt ttcgaagaag
    45121 ttacttctgg aataccatgt attagaggtt gtgaaaaagc tgcttagttt caagtagtaa
    45181 gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa atttgactta ctaccgagaa
    45241 actggctttt gaacaccgtt tatcgagagg ttgtgaaatc agcgtcctga cctgagtatt
    45301 agagaaaaaa acggaaaaat agttcctcat attttgccgt ttgttgagct aataccgagg
    45361 gtcagctgat tgaacaccgt ttagtggaga gattgtgaaa aagctgtcct gcatcaagta
    45421 ataagaacag ccaatcaaaa gcagcaagga gaacctcatc tataaaaaga tagaaggaag
    45481 tgagacatct attggtctca tttccttcta tttttacttt cctcagtcaa ttgttttaca
    45541 tcataaaagg agaaattcca cttatttttt tcgctgtttc atgacataaa caactacacc
    45601 gattaacaaa attcctccag ctaatgctag caacgggtta ttaaattctc ccgtttttgg
    45661 gagtccttga gtgccatttt tttcactttc ttttgctgtc ctatccggat gagaaggttt
    45721 tccatttggt tttccatttg gtgattcatt tcctggattt tctctttctg gtttgtcatt
    45781 tcccgggggc acatcggcag tttctcgcac agtgatcgct ttttgctggg taacagattc
    45841 tgtatgagca gaccattttt ccccatcaaa tatttccgaa cgataagtga cttctagcgt
    45901 atattctcct tttgaaggtg ctgaaaaaat agcggtatga ttagaaaatt gagcacttga
    45961 ctgtgtttca acgatttgga tcttttctgg gaaataacgc atatcttcaa agacaggcgt
    46021 tccttgattt ggtgtgaaag ttgacacaaa aactgtaaaa ggcttcagtt caatgatatt
    46081 tccttctgca ttctccgcca caccatttgc ttcttgtata ataatcggat tattttgttc
    46141 atttggtttt gtctgatttg gttcttgtac gattgcatac tctggatatt ccgaagacgg
    46201 tgaggtttct ccgtcaaaaa tagcacctac agataatgga agaccatcca ctctttcctt
    46261 ttctgtttga cgattccccg gtttaatctg catcagtcca tgaacatgga tacttccatt
    46321 ttcatagcgc gtaacaggct gctgaccttc tttcgaacat gtatttagag actcgatcca
    46381 atcttttgat atggtatgtc caagagtatt ttctgattgt ttctctcgtt cattccaata
    46441 gtagttcaac gagtggtaga tttgatcttc gttttgattc aatgggcgga tctgctctct
    46501 catctcaaga ttctctgttc ggaaagataa gataccagaa gcatggtagt ctgtgtttcc
    46561 tgctgaagag gtataaagag ccacattata tgaaccgtta ttaaaacttg tactgctatt
    46621 gacgataata tctgttccgc tattggaatc gattcctttc gcaagatttt cgaaagacaa
    46681 actattgatc aattcatgag ggcccgttaa agaagaaccg cccattttga atccattacc
    46741 gttaccttct ccctcaattc ctggtaccca gccgtttcga taagcaactg agtttttgat
    46801 gattactttt ccgatcgaac ctgtttcatt tttagcaaaa aggtcccaac cgtcatctgc
    46861 attatgatac gcgatacaac cgtcaaatac atttccttct cctattgtca gtttggccgc
    46921 aaatccatcg gcatcttcaa atcctggatc ggcattttca aaagatgtac agttcttgac
    46981 taagttatgc gcgggccatg cttcgaaagg atcatttgag ctaccgctga tttggattcc
    47041 tgtatttcca ttccgataag catgaatctc ttcgatcaaa ttatgatttc cagaaatctg
    47101 taatcctttt tgcatagctg cactatttgt aatgtcaaac cctcgtaaac cccagtagtg
    47161 actgaacagt gtcatcccat ttccagttcc tttaaaatca agtacaggac gcttgttttc
    47221 tggatttttc tctgcaatca actgaatcgg gttttctctt gtcccgttaa cgccttttgg
    47281 aatcgtcaat cctctttcga aggaataagt tccaggcgcc atgacgattg tctgcccagc
    47341 atatgcgtat ctcaatgctt gtgtcagaga taatggattt tgtctgcttc cgtttcctgc
    47401 atctgaccct tctggtgtta cataaactgt cgaatattta ggtttacggt agtccactgt
    47461 atgaagaatc tcttttgttt cataactagt catctctacg tattcttctg gcggatagtt
    47521 tttatctggc gtaaaactga aagtaaattc gttcgttcct tccatcagtt ttgtctgata
    47581 atcaaattcc cgattcgcag tgatagccaa gttttttgcg ttcttaagca cctctcctgt
    47641 tgctttattt ttaattgtca ataatccgtc agcatttgct ctaaaggaca tagtatgatc
    47701 ttggtttcct gaatgattac tagaggtcac agtgtaaatc ggatcaatca agcgagtagg
    47761 tctttcttgc ccaggaggat ctgtcgcagg atctgagtaa gcaacttcga ttccttctac
    47821 cttgatcgtc atattccttg ctgcagcaaa tcctgcataa ataaccgatt catctgaagc
    47881 gtataatttt tcccagtcat acatgatgtc agaagccatt tcttctcctg tttcaggatc
    47941 gtaataatat gcctctaaac cagtattcgt ttttttcatc tctacgtcca gtttagtaat
    48001 cgagttcgtg gccggaaaca gattcccatg accgtttccg aatatattat aagaacctgt
    48061 ttctttttcc aagaaccctg ctgaagtctc taaaggtgtt gtttccactg agacactccc
    48121 aggagctggc gcagcttgcg gatcttcaga tgatattcct gtgattgccc gtgtccccaa
    48181 tccaagtcgc atcgtatatt tgctgccgct cgtgttgacc acttcttgtc tatccgagtc
    48241 ccagacatat tcgatccgac tgcctagtat ggcaaatgaa tttgaataaa atgcctgccc
    48301 aaacaaatga ttttttggta ctgcgtctct taccattaaa gcaaatcctt cttgggcatt
    48361 cgtataggtc caagattcta tttcgatcgt cgcccgcatc ctaaagttga tgtctttggg
    48421 gattgcttga taataatagg tcattccatc tgatccgctt gactggaatt ttccgccgtt
    48481 attcgtggaa gagagccgca cgccgtcttc taatggttca atggcatacc tactagcact
    48541 tgtgctttct ccgaaaacaa cccctttcca ctcttcattt gcttcttcag attgcttttt
    48601 tgtcttttca ttttctgatt ctttcatcat aggatcattt ccttcttccg tatccatatc
    48661 ttcactagtt cttggtattt cctccattgt tgacatccct tcaatgttca cgtgtgcatt
    48721 ttcttcgttc acagactgtt gttcgttagc agcaacttca acgacagaaa ttaaaaccgg
    48781 ggtactgagc ataaggagat tcatcattag cgcactgtat tttatacgtt tttttaacaa
    48841 gtgtattcct cccgtaacaa attagaaagc gtttacttaa agtattacct aatttatttt
    48901 tactgtcaat aaaaaacaaa attataataa gtgtatttta taaaaagaaa aaatataact
    48961 taagttgtt
//
LOCUS       DADQDV010000015        48440 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.015, whole genome shotgun sequence.
ACCESSION   DADQDV010000015 DADQDV010000000
VERSION     DADQDV010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 48440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48440
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.015"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(45..869)
                     /gene="iolB"
                     /locus_tag="J8S10_000908"
     CDS             complement(45..869)
                     /gene="iolB"
                     /locus_tag="J8S10_000908"
                     /EC_number="5.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-deoxy-glucuronate isomerase"
                     /protein_id="HAZ9629511.1"
                     /translation="MEKTLKHQPLNKELAPGVKQIQNIRQSNSALSYIEFQILELEKG
                     ASYKETGSQQEVCIVILTGKIKVKAADTWYEDLGTRESVFEKIPTDSIYLPAEHSFEL
                     VATTDNVRLALCYSPAKKALPISVIRAEDNTVEERGLYQNKRLVHNILPDNVDTASSL
                     LVVEVYTEGGNFSSYPPHKHDQENLPHESFLEETYYHELDPEQGFVFQRVYTEDRSLD
                     ETMTVEHQNVVEVPKGYHPVGVPDGYTSYYLNVMAGPERIWKFHNEKKHEWILQRK"
     gene            complement(908..2824)
                     /gene="iolD"
                     /locus_tag="J8S10_000909"
     CDS             complement(908..2824)
                     /gene="iolD"
                     /locus_tag="J8S10_000909"
                     /EC_number="3.7.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002397168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3D-(3,5/4)-trihydroxycyclohexane-1,2-dione
                     acylhydrolase (decyclizing)"
                     /protein_id="HAZ9629512.1"
                     /translation="MEKTVCLTTAQALLKFLNQQYISIDGKETPYVEGIFHVYGHGNV
                     LGIGQALELEPGHLKSYSGKNEQGMAHAATAFARQNLRKKIFAVSTSVGPGAANLLTA
                     AGTAFANNIPVLFLPADTFATRQPDPVLQQLEHASSVAFSTNDAFQAVSRYWDRINRP
                     EQLMSALLRAFEVMTNPATMGPATICLPQDVEAEAYAYPEEFFKKRVHYIDRRIPTAR
                     ELAEASQRIKASKRPVIIVGGGCKYSEAGEILEQISRDCQIPLVETHAGKSTVSWDFK
                     NNLGGMGILGTSAANKAVQQADLIIGIGTRYTDFTSASKSIFNFEQAKMMNINVSRQQ
                     AAKLEAFQVVGDAKATLEQLAPMIEGYQTAYGEKIDELKEEWISERNRLKAAHFKRKD
                     FTPEIKDHFSQEILNEYADALATNLTQTEVFIHLNDFVDEDAIVIGSAGSLPGDMQRL
                     WNPVKENTYHLEYGYSCMGYEIAGAMGVRMARPEQEVYALVGDGSFLMLHSELVSSLQ
                     YDKKINIVLFDNSGFGCINNLQMDNGGASQGTEFRNTKDEIMNIDYAKVAEGYGAKTY
                     RVSSIAELQAAVEDAKKQTRSTLIEIKVLPKTMTEGYDGSWWNVGISEVSGKAAMQEA
                     YKAKQAKLATIRKY"
     gene            complement(2835..3869)
                     /gene="iolC"
                     /locus_tag="J8S10_000910"
     CDS             complement(2835..3869)
                     /gene="iolC"
                     /locus_tag="J8S10_000910"
                     /EC_number="2.7.1.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018593001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-2-deoxygluconokinase"
                     /protein_id="HAZ9629513.1"
                     /translation="MSYIKFDQSKEFDLLLLGRVAIDFNPAYNDQVKEEFKPLKKVHM
                     FEKFVGGSPANIAVGVTKHGMKAGFIGTVSDDQFGEYVIDYFNEQGIDTSQISKAQHG
                     EKLGLTFTEMLSSKESNILMYRNQAADLQLSVEDIDEDYLKRSKALLISGTALAESPS
                     REAVIKAVMLAKRNNVKIIFDIDYRAYNWKNNDDISIYYSMIAKESDIIMGSREEFDL
                     TEKLIQPNMSDNESAAFWHSCGAEIVVIKHGMKGSTAYTADQQQFSIKPFPVEARKGF
                     GGGDGYGSGFLYGLFEGWEIIDCLEFGSAEASMMVKSNNCSDSLPTTQEVKDFITLEK
                     EIYGEMIARI"
     gene            complement(4026..5042)
                     /locus_tag="J8S10_000911"
     CDS             complement(4026..5042)
                     /locus_tag="J8S10_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016633586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAZ9629514.1"
                     /translation="MAGTIKEIAEKAGVSRGTVDRALNDRGRINPEVAERIRAIAKEM
                     NYVPKKKKVIKETTLKLGIVTQLAKSSFMIPIRSGLESIIGDLKKRNIDCFLEEVDGV
                     DEAAQLQALDRLVELGVKGIAIMPVDSDGIREKINQLTDQGILIITFNSDILGTNRQC
                     FVGMDNFKSGKTAAGLLGMLTKGKGKVLAITGYFGNSVNSLRVAGFVEELKESFPELE
                     LTGVQSSFDSSAEVEKILSNTLENYSNLDGVVVFSGGQAGIARALEKIDESKRPFVII
                     YDLTKNNIEMLKNDQVDFLIDQDGFVQGYRSLLMLANQLQNNKTVTKDALFTDIIIKT
                     KYNI"
     gene            complement(5144..5341)
                     /locus_tag="J8S10_000912"
     CDS             complement(5144..5341)
                     /locus_tag="J8S10_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629515.1"
                     /translation="MKFICLSCGEKESIPMDVVKFLDDADIANDPNNPPQFTCEKCGK
                     EMYPEYYRNALGIEFKISDVQ"
     gene            complement(5313..6632)
                     /locus_tag="J8S10_000913"
     CDS             complement(5313..6632)
                     /locus_tag="J8S10_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011674482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS91 family transposase"
                     /protein_id="HAZ9629516.1"
                     /translation="MKANILEAIFFDEHHNWDNFVEKYGRKIRLVVKREVNKFRYCGD
                     IQKGYRLFVCEGCHQTKFVPLKCRGKFCPTCATGESQRWSAVVANDMFKVTHRHVIFT
                     IDEGLREIFMMENYRDSLLKGLMDEAAKIILAYFEKRKVKAGIVATIHTFGSKLEFNP
                     HVHMVVTMGGLTRDGSWEEYDYLPFSMLRKYWKNAVLKLIRRTLGEWDKQRVQSRLQA
                     AYKNNGEGFYVNAPKRSRTNLKSLLQYISRYMKRGPIALSRILMYDGDTVMFNYMDKR
                     TNTKETMTMSIDEFIAALIRHIQNKNFKTIRRYGIYSRRIKTLMKKVMKEYQKRVKKL
                     FINLNEALRPKSWEERITEEFGENPLECSCCGEYYEFVGMSVRKNGRLVIKYAKDNHA
                     KRFMREENRKIDQKEFRQQYEEEKEKTFKAIRWDWERQREIYMSKLW"
     gene            complement(7373..8353)
                     /locus_tag="J8S10_000914"
     CDS             complement(7373..8353)
                     /locus_tag="J8S10_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HAZ9629517.1"
                     /translation="MLFLKKEDIIKSFSMREAIDADKKALSLYSAGKASVPLRTNIDV
                     PKSNGQSLYMPAYVEGGEGALGVKIVSVYPENIKKNLPSVPATMIVLDPETGMVSACL
                     DGTYLTQLRTGAVQGAATELLAREDAKIGALIGTGGQAQSQLEAMLTVRKLEEVRIFD
                     IDFERASQFAEKMMQQFSVTMRPTKTSQECVEGADIITSVTTSKRATFSAEWVKKGAH
                     INGVGAYTPEMCEIPREIIKAADVVIFDTMDGVLKEAGDFISPLQDGYIQRDSYHGEL
                     GQLINEELIGRTSGEQITIFKTVGSAVLDVVVATEIVKKAKENNLGKLIF"
     gene            complement(8366..9244)
                     /locus_tag="J8S10_000915"
     CDS             complement(8366..9244)
                     /locus_tag="J8S10_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HAZ9629518.1"
                     /translation="MIRNILLTLIVAINLYFIIYFLRDLFKNKQNFKEEPGDMRLLPF
                     TSFIIFFLSTFGVSDFAIGTVLYPKLKWVSMKKLPGTLNTQCVVPVAVMALSYITAIN
                     VGIKTLAVCIICQIIGAYLGPRFVVKLPEKTIKLFVGIGLVIAALLIFAGQMNWIPSN
                     GTASELYGGKLILAGFLLFVYGALNNIGIGSYALTMVTVYLLGLNPVAAFPIMMGACT
                     FSVPIGSVQFIKFNEYSRKITLFTSTFGVLGVLVAVFLVKSLDTYILKWIVILVLLYS
                     AYTMLGSQLKKVTAAN"
     gene            complement(9260..10060)
                     /locus_tag="J8S10_000916"
     CDS             complement(9260..10060)
                     /locus_tag="J8S10_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HAZ9629519.1"
                     /translation="METIIQIMKKYDFSEMETRVYTTLLEKGNLTGYEVSKISGVPRS
                     KVYNILEKLLKKNLIVVNKSEPKLYHAISANEFLEKLEKSVKNDLSFLTKNLGMIKEK
                     DEEEMLWKVDGIEYVLDKVEHLVKNAKESLLIQVWHENFTDSLLKALQQAEKRVDKFV
                     LILFSSTHEYDLPLEKYYIHGFETDKLADFGARWINIVADEQEVVFGTINEELQSTDV
                     TWTKNHAMVNLAKEYVKHDAYTLKVIAESPEELKAKYGEGFEGIRKIY"
     gene            11452..11778
                     /locus_tag="J8S10_000917"
     CDS             11452..11778
                     /locus_tag="J8S10_000917"
                     /inference="COORDINATES: protein motif:HMM:NF013698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAZ9629520.1"
                     /translation="MFKIFRKNCCGLDVHKTWIYACIGITDANGRTVYKQARFSSFTK
                     GLNELAEWLAKYNCKDVCLESSGKFWIPVFNILEKTCFVTLAHPKYTKPQKGNKTDRK
                     DAKMDL"
     gene            11786..12694
                     /locus_tag="J8S10_000918"
     CDS             11786..12694
                     /locus_tag="J8S10_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAZ9629521.1"
                     /translation="MCDMIKPSFIPGLEIRQLRDLMRYRTKLTNMKTSEKNRALNCLT
                     VSNLKLDDVFSDVFGKSSTSIIQYLLEHPGESFDVRPFIHARCKTPVEEIQAAVEGAI
                     SVPQAIKLRQCLNHINEIEKHREEINLEIQALAEPFSPVLELLRTIPGLDTQPITAIA
                     ILSEIGPDMSVFPTSKHFISWAGCCPRNDRSARRTKSTRISRAGQSLKPLLVQIANAL
                     LRSKEHPEFKNRYRRIKANRGHKKAIIAICKMLLTAIWNVLSKVEPYSAKGYLEPKPA
                     KEEKVLTQSQALDLLRKRGYTIIDSA"
     gene            13323..13574
                     /locus_tag="J8S10_000919"
     CDS             13323..13574
                     /locus_tag="J8S10_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HAZ9629522.1"
                     /translation="MKSNQKSGFYTFIKAISSVLECDCIIGPYSMLIKMGFPSTESLD
                     SFINDLSKFGRTNTQIVFSTLVSLMVYQFWNVYHALLLK"
     gene            14116..14274
                     /locus_tag="J8S10_000920"
     CDS             14116..14274
                     /locus_tag="J8S10_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAZ9629523.1"
                     /translation="MNKKQACEFLGIDNNTLDKWIRVYNFPVIKIDGVVRFDVEDIKD
                     FMNTFKKN"
     gene            14346..15572
                     /locus_tag="J8S10_000921"
     CDS             14346..15572
                     /locus_tag="J8S10_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAZ9629524.1"
                     /translation="MPTKLSNGKYKTNLRYPKKFREITGIASEKYQKVFPTRQLAIKA
                     EREMKKKIETVLREENANSLELKGKIKFKDFYESKWLPRYELGQTTRSNRAPSNVTIS
                     NTKDIFRLHILPMFGEYAMNYLNSNTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILCYIEFNRTTKIIQCITAPKKMALEEKRIREGNQALSSEELTDWIEAVNNDLNNHLL
                     TLHDYTLFMLTLYLGDRKSETYALQWKYIDFNKNTVRLKYALDKYQRKTHTKGWKDTV
                     IQAPEVVMTLLREWKSAQAEQLLKLKIIQTPDQYLFTYSKPSGEVNCPVHADYLNYRI
                     NAIKKRHPELAQLSPHKLRHTYATIAREGGANMNQISNALTHSDISTTKIYVNTPDVV
                     DKSVFEAFQKGLNKCD"
     gene            complement(15661..16053)
                     /gene="rpsI"
                     /locus_tag="J8S10_000922"
     CDS             complement(15661..16053)
                     /gene="rpsI"
                     /locus_tag="J8S10_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HAZ9629525.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(16069..16512)
                     /gene="rplM"
                     /locus_tag="J8S10_000923"
     CDS             complement(16069..16512)
                     /gene="rplM"
                     /locus_tag="J8S10_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HAZ9629526.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(17031..17498)
                     /locus_tag="J8S10_000924"
     CDS             complement(17031..17498)
                     /locus_tag="J8S10_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HAZ9629527.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(17618..19156)
                     /locus_tag="J8S10_000925"
     CDS             complement(17618..19156)
                     /locus_tag="J8S10_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HAZ9629528.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            19236..19922
                     /locus_tag="J8S10_000926"
     CDS             19236..19922
                     /locus_tag="J8S10_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HAZ9629529.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(20123..20650)
                     /gene="msrA"
                     /locus_tag="J8S10_000927"
     CDS             complement(20123..20650)
                     /gene="msrA"
                     /locus_tag="J8S10_000927"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAZ9629530.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(20734..21411)
                     /gene="pgmB"
                     /locus_tag="J8S10_000928"
     CDS             complement(20734..21411)
                     /gene="pgmB"
                     /locus_tag="J8S10_000928"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HAZ9629531.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(21408..22536)
                     /locus_tag="J8S10_000929"
                     /pseudo
     CDS             complement(21408..22536)
                     /locus_tag="J8S10_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
     gene            complement(22536..24719)
                     /locus_tag="J8S10_000930"
     CDS             complement(22536..24719)
                     /locus_tag="J8S10_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HAZ9629532.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(24716..25741)
                     /locus_tag="J8S10_000931"
     CDS             complement(24716..25741)
                     /locus_tag="J8S10_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAZ9629533.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTANRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(25786..26613)
                     /locus_tag="J8S10_000932"
     CDS             complement(25786..26613)
                     /locus_tag="J8S10_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAZ9629534.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(26610..27677)
                     /locus_tag="J8S10_000933"
     CDS             complement(26610..27677)
                     /locus_tag="J8S10_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HAZ9629535.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(27703..28539)
                     /locus_tag="J8S10_000934"
     CDS             complement(27703..28539)
                     /locus_tag="J8S10_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAZ9629536.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(28536..29405)
                     /locus_tag="J8S10_000935"
     CDS             complement(28536..29405)
                     /locus_tag="J8S10_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAZ9629537.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(29475..30758)
                     /locus_tag="J8S10_000936"
     CDS             complement(29475..30758)
                     /locus_tag="J8S10_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAZ9629538.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(30772..32457)
                     /locus_tag="J8S10_000937"
     CDS             complement(30772..32457)
                     /locus_tag="J8S10_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HAZ9629539.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            32732..33757
                     /locus_tag="J8S10_000938"
     CDS             32732..33757
                     /locus_tag="J8S10_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAZ9629540.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(34352..38005)
                     /gene="rpoC"
                     /locus_tag="J8S10_000939"
     CDS             complement(34352..38005)
                     /gene="rpoC"
                     /locus_tag="J8S10_000939"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HAZ9629541.1"
                     /translation="MIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYRTLKPERE
                     GLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHIELAAPVS
                     HIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTEREYREKRE
                     QYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLDILEAFRA
                     SGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLKRLLDLNA
                     PGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKNAKRKIER
                     QEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVCEAYNADF
                     DGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTMEEEG
                     REGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMITTVGKII
                     FNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKKKNLGNII
                     AEVFKRFKVKETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIENAHKQVET
                     ITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSGARGNISN
                     FTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTRKEVRHPE
                     TNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNLATGSDVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNPKGQAVIT
                     EVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGAPLTEGSI
                     DPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRVMDPGDTD
                     ILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAASFQETTRV
                     LTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVYSISDIEA
                     QMAAEDAMNNQTK"
     gene            complement(38084..41701)
                     /gene="rpoB"
                     /locus_tag="J8S10_000940"
     CDS             complement(38084..41701)
                     /gene="rpoB"
                     /locus_tag="J8S10_000940"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HAZ9629542.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLFALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            42429..43397
                     /locus_tag="J8S10_000941"
     CDS             42429..43397
                     /locus_tag="J8S10_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAZ9629543.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            43415..44320
                     /locus_tag="J8S10_000942"
     CDS             43415..44320
                     /locus_tag="J8S10_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9629544.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGSAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            44317..45123
                     /locus_tag="J8S10_000943"
     CDS             44317..45123
                     /locus_tag="J8S10_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAZ9629545.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            45280..46248
                     /locus_tag="J8S10_000944"
     CDS             45280..46248
                     /locus_tag="J8S10_000944"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HAZ9629546.1"
                     /translation="MTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKAIKELEKA
                     GYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMMTSESTMKDAKLAAAQGD
                     SVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTIIAASACVK
                     AIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLNFSVPQNH
                     FPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKSFVLGKTV
                     SFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(46565..47089)
                     /locus_tag="J8S10_000945"
     CDS             complement(46565..47089)
                     /locus_tag="J8S10_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinB family protein"
                     /protein_id="HAZ9629547.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            47376..>48440
                     /gene="scm"
                     /locus_tag="J8S10_000946"
     CDS             47376..>48440
                     /gene="scm"
                     /locus_tag="J8S10_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HAZ9629548.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSS"
BASE COUNT        13794 a        10414 c         8826 g        15406 t
ORIGIN      
        1 ctaactaaac ctaactaaac tttatgtatc taacagctta ataactactt gcgctgcaag
       61 atccattcgt gtttcttttc attgtggaat ttccaaattc gctcaggtcc cgccatcaca
      121 tttaaatagt aggaagtata cccgtcaggt accccaactg gatgatagcc cttaggaact
      181 tcgacgacat tttgatgctc taccgtcatc gtttcatcta gtgaacgatc ttccgtgtag
      241 acccgctgga aaacaaatcc ctgctctgga tcaagctcat ggtaataagt ttcctctaaa
      301 aaagactcat gtggcagatt ctcttgatcg tgcttatgag gaggatagct ggaaaaatta
      361 ccgccctcgg tataaacttc gacgaccagc aggctgctgg cagtatcgac attatccggt
      421 aaaatgttgt gaacaagtcg tttattctga tagagtccac gttcttcgac ggtattatcc
      481 tccgcgcgaa tcacacttat cggcaaagct tttttcgctg gtgaatagca aagcgccaat
      541 cggacattgt ctgtagttgc cacaagttca aacgaatgct ccgccggaag ataaatactg
      601 tcggttggaa ttttttcaaa aacagattct cgtgttccta aatcttcata ccaagtgtct
      661 gctgctttaa ccttaatttt tccagtcaaa atgacgatac agacctcctg ttgactgccg
      721 gtttccttgt aagaagctcc cttttccagc tccaaaatct gaaattcgat ataactcaaa
      781 gcagaattag actgccgaat attttggatt tgttttactc caggtgccag ttctttgttt
      841 aatggttgat gcttcaatgt cttttccaat caatccactc cttattttca atcacaaaaa
      901 gcaatattta atactttctg atagtggcaa gtttcgcttg tttggctttg taagcctcct
      961 gcatggctgc tttacccgat acctctgaga taccgacgtt ccaccagctg ccgtcgtagc
     1021 cttctgtcat ggttttagga agtaccttta tctcaatcaa cgtcgatcgc gtttgcttct
     1081 tcgcatcctc gaccgctgct tgtaattctg caatcgagct tacacgatac gtttttgcac
     1141 catagccttc agcaactttg gcgtaatcga tgttcatgat ctcgtccttg gtatttctga
     1201 attcggttcc ttggctagct ccgccattat ccatctgtaa attattgata cagccgaaac
     1261 cagaattatc gaaaagtaca atgttgattt ttttatcata ttgcaaacta gaaaccagct
     1321 cgctatgcaa catcaagaaa ctgccatcgc ctactaaggc atagacctct tgttctggtc
     1381 gagccattct tacgcccatc gcaccagcga tttcatagcc catacaagaa taaccgtatt
     1441 ccaaatgata ggtattctcc ttcacagggt tccataagcg ctgcatatcc cccggcaatg
     1501 aaccggctga accgatcacg atcgcatcct catcaacaaa atcatttaaa tgaatgaaga
     1561 cctctgtttg cgtcaaattc gtagccaacg catcagcata ttcattcaag atttcttgag
     1621 aaaaatgatc tttgatttct ggcgtaaaat ctttacgctt aaaatgcgcg gcttttaacc
     1681 gatttcgctc actgatccat tcttccttca gttcatcgat cttctcgcca taggcggttt
     1741 ggtaaccttc gatcattggg gcaagctgct ccaaggtcgc tttcgcatca ccaaccactt
     1801 gaaaggcttc cagcttagcg gcctgttgtc tgcttacgtt aatattcatc attttcgctt
     1861 gttcaaaatt aaaaatactt ttagaagctg aggtaaaatc agtgtagcgt gtgccgatcc
     1921 ctatgatcag atccgcttgc tgcacagctt tattagcagc cgaagttccc aaaatcccca
     1981 ttccgccgag attgttttta aaatcccacg aaacagtcga tttacctgcg tgcgtttcaa
     2041 ctagcggaat ctgacaatct cttgagattt gctcaagaat ctcaccagcc tccgaatatt
     2101 tgcagccgcc tcctacgatg atgacaggtc gtttactggc ctttattcgt tgactcgctt
     2161 cagcaagctc acgagcggtc ggaatcctgc gatcaatata atgtactctt tttttgaaaa
     2221 attcctccgg ataggcatag gcttctgcct ccacgtcctg cggcaaacaa atcgttgccg
     2281 gacccatcgt tgccgggttc gtcatgactt caaaggcccg caataacgcg gacatcaact
     2341 gctctggtcg attgatgcgg tcccagtagc gagaaaccgc ttgaaatgca tcatttgtcg
     2401 aaaaggctac actgcttgca tgttccagct gctgcaagac cggatcaggc tgacgtgtag
     2461 caaacgtatc cgccggtaaa aaaagtacgg ggatattatt tgcgaatgcc gtacccgctg
     2521 ctgttaacag attggccgcg cccggtccaa cagatgttga tacggcaaaa attttcttgc
     2581 gtaaattctg tctggcaaag gcagtagccg catgggccat tccctgctca ttttttccgc
     2641 tataactttt caaatgtccg ggctctaatt ccagcgcctg accgatcccc aaaacatttc
     2701 cgtgaccata gacatgaaag ataccttcaa cataaggcgt ttctttgccg tcgatgctga
     2761 tgtattgttg attcaaaaat tttagtaatg cttgtgctgt tgttaaacaa accgtctttt
     2821 ccattttttt caccttaaat ccgagcgatc atttcgccgt atatttcttt ctccaatgta
     2881 ataaaatctt ttacctcctg agtcgtcggt aaagaatctg aacagttatt gcttttgacc
     2941 atcattgatg cttccgctga gccaaactct aaacaatcga tgatctccca gccttcgaat
     3001 aaaccgtata agaaacccga gccgtaacca tctccgccgc caaagccttt gcgtgcttcc
     3061 accggaaacg gcttgattga aaactgctgc tgatcggccg tataagcagt cgatcctttc
     3121 attccatgtt tgattacgac aatctcagca ccacaactgt gccaaaaagc agcgctttca
     3181 ttatctgaca tgttaggctg gatcaacttc tcagttagat cgaactcttc tcttgaaccc
     3241 atgataatgt ctgattcctt agcaatcatc gaatagtaaa ttgaaatatc atcgttgttc
     3301 ttccagttat aagcacggta atcaatatca aaaataattt tgacattatt ccttttcgcc
     3361 agcatcactg ccttgattac ggcttctctg gacgggctct ctgctagtgc agttcctgag
     3421 attaatagtg cttttgaccg tttcaagtag tcctcatcaa tatcctcaac gctaagctgc
     3481 aggtctgcgg cttgatttcg atacatcaaa atattacttt cctttgatga gagcatttcg
     3541 gtaaaagtca gccccagctt ttcaccatgc tgcgctttgc tgatctgaga cgtatcgatg
     3601 ccttgttcat tgaaataatc gatcacatat tcgccaaact gatcgtccga gactgttccg
     3661 ataaaaccag ctttcatgcc atgtttagta acacccacag caatattggc aggagatccg
     3721 cccacaaatt tttcaaacat atggaccttt ttcaatggtt taaactcttc tttgacttga
     3781 tcattgtagg caggattaaa atcaatagcg actcttccta aaagcagcaa gtcaaattct
     3841 tttgattggt caaactttat ataactcaat atatccacct ctttatccgt tcttctattt
     3901 ctgaggcaag tatagcacgc caaaacaaag cgtgcaatat ttattttaga acgcaatatt
     3961 gcgtgctgtt tgaaaatgac ggcaaaaaaa acgtgaatcg ccttacatca cgattcacgc
     4021 ctagattaaa tattgtattt tgtcttaata attatatcag taaatagcgc atcttttgta
     4081 accgttttat tattttgcag ctgattcgct aacatcagta atgaacgata gccttgaaca
     4141 aatccatctt gatcgattag aaaatcaacc tgatcgtttt tcagcatctc gatattgttc
     4201 ttagtcaaat cataaatgat tacaaagggc cgcttgcttt catcgatttt ttccaacgct
     4261 cgggcaattc ccgcttgtcc gccagaaaag acgactacgc catctaagtt tgaataattc
     4321 tccaaggtgt tgcttaaaat cttttcaacc tcagcactcg aatcaaagct gctctgaaca
     4381 cccgtcagct ccagttcagg aaacgactct ttcaattctt caacaaagcc tgccacccgt
     4441 aagctgttga cgctatttcc aaagtagccg gtaatcgcta gaaccttgcc ctttcctttt
     4501 gtcagcatac ctaacaatcc cgcagccgtt tttccgcttt tgaagttgtc catcccaaca
     4561 aaacactgtc gattcgtacc aagaatatcc gaattaaagg taatgatgag gatgccttga
     4621 tcggtcaatt gattaatttt ttctctgata ccatcactat ctactggcat gatcgcgatc
     4681 ccttttactc caagctccac caatcgatcc aacgcctgca gctgggccgc ttcatcgacc
     4741 ccgtctacct cttctaaaaa acaatcaatg tttcgctttt ttaaatcccc gataatagat
     4801 tccagacctg atcggatcgg aatcataaaa gaagatttcg ccaattgagt gacaatcccc
     4861 agcttgagcg ttgtctcttt tatgaccttc tttttctttg gaacatagtt catttccttg
     4921 gcgattgctc tgattctttc tgcaacctca ggattgatcc ttcctcgatc gttcaatgcc
     4981 cgatccactg tcccccttga cactcctgct ttctcagcta tttctttaat tgtacccgcc
     5041 atcttgcctc tccttttttc ctattgtgtt tattttatca caaaacttaa gaaaaccacc
     5101 ggagaatgaa ttctccggtg gactttttgt atgattaacc ttcttattga acatcactga
     5161 tcttaaactc tattccaagg gcgtttctat aatattctgg atacatctcc ttcccacatt
     5221 tttcacaggt aaattgggga ggattgttcg gatcatttgc aatatctgca tcatctaaaa
     5281 attttactac atccattggg attgattctt tttcaccaca acttagacat ataaatttca
     5341 cgttggcgtt cccaatccca gcgaattgct ttaaaagttt tttctttttc ttcttcatac
     5401 tgttgcctga attctttttg gtcaattttt cgattctcct ctcgcataaa ccgctttgca
     5461 tggttatctt tcgcatattt aataactaac cgtccatttt tgcgcacact catcccaacg
     5521 aattcatagt actcaccgca acaagaacac tctaagggat tttcaccaaa ttcttcggtt
     5581 attctttctt cccaggattt tggtcttaag gcctcattca gattgataaa cagctttttt
     5641 actcgtttct gatactcctt catgaccttt ttcattaatg ttttgattct acgactatag
     5701 attccatagc gacgaatcgt tttgaaattc ttattttgaa tatggcgaat cagtgcagct
     5761 atgaattcgt ctatactcat ggtcatcgtc tctttagtat tcgttcgttt gtccatgtag
     5821 ttgaacatga cagtgtcgcc atcatacatt aagattcggc ttaatgcgat cgggccacgc
     5881 ttcatataac gactgatgta ttggagtagt gactttagat ttgtcctgct ccttttagga
     5941 gcatttacgt aaaacccttc tccattgttc ttgtacgcag cttgtaatct tgattgaact
     6001 ctttgcttgt cccactcacc taacgttcgt ctaattagtt tcaatacagc atttttccag
     6061 tattttctta acatagaaaa aggtaaataa tcgtattctt cccaacttcc atctcttgtt
     6121 aagccaccca tagtaacaac catatgaaca tgcggattaa attctagttt tgatccaaag
     6181 gtgtggattg tagctactat acctgccttc acctttcttt tctcaaaata ggcaagaata
     6241 atttttgcgg cttcatccat tagtcctttc agtaaggaat ctcgatagtt ttccatcata
     6301 aagatttccc gtaacccctc atcgatcgta aagattacgt gccgatgtgt cactttaaac
     6361 atatcattcg ccacaaccgc tgaccacctt tggctttcac ctgttgcaca cgttggacag
     6421 aactttccac gacatttcaa gggaacaaac tttgtttgat gacatccctc gcagacaaac
     6481 agtcggtatc ctttttgaat atctccacaa tatctaaact tgtttacttc ccgtttgacg
     6541 actagccgaa tctttcgccc gtatttctca acaaagttat cccaattatg gtgttcgtca
     6601 aaaaagattg cttcgagaat attcgctttc atagtaatat tttacttgtt caaaaacaaa
     6661 atgaaaaggg ctaaaagact ggtagtgcag cctttttagc ccttaacttt ttatactttc
     6721 tttactgtct aaaaaatatg cggcgcacag aacgcgccgc atatcggact aagttttatt
     6781 caaatttgtc ttcgccaaca caatttgacg aagagccttt tctttcagga agacttcggt
     6841 aatttttagg agttctacct attcttttaa ccgtttattc tctttttcta agcgtgtaat
     6901 ttcatttctg cgaatggatt tcatgacttc ctctaccgag aaaagtacgt tatccatatt
     6961 tttcaacttc ttgaactcat caatacacgc tattagagcg agcttctagc tatagactaa
     7021 cttctttaac agaaaaccct tcttccgtta ccagttttac agcggtaatt ttaaatattt
     7081 catcaaatga acgtcttggc ataatccaga tcttcgcttt ctcttaattt ggtgtcaatt
     7141 ttagtataac ccgtccaact tattttttaa ctaagtgccc ggtttttctt gacaactcca
     7201 cccaaaagtt agattttttg gtctaagttt tagggtcgct tcattactag aattcaacaa
     7261 gagatgtttt ttattttatt taaattatgg ggtcagtttc catttgatta caaacttctt
     7321 tgttttcttt ttttaaacgc aataataaag gttttaattt cagccttttt aattagaaaa
     7381 tcaattttcc caaattattt tctttagctt tcttaacgat ttctgtcgca actaccacat
     7441 ctaatacagc cgaaccaact gttttgaaga tcgtgatttg ttctccactt gtccgaccga
     7501 tcaattcttc attgatcagt tggcctagtt ccccatgata gctgtctctt tgaatatacc
     7561 catcttgcag cggtgaaatg aagtccccag cttcttttag aacaccgtcc atggtatcaa
     7621 aaataacaac atctgcggct ttgattattt ctcgtggaat ttcacacatt tccggtgtgt
     7681 aagcaccgac tccattgatg tgcgcacctt ttttgaccca ctcagcagag aatgtcgcac
     7741 gttttgaagt ggtcacactt gtaatgatgt ctgctccttc aacgcattct tgactggttt
     7801 ttgttgggcg catcgttaca gaaaattgtt gcatcatttt ttcagcaaat tggctggcac
     7861 gctcaaaatc aatatcaaaa atccgaactt cttctaattt acgaacggtc aacattgctt
     7921 ctaattgtga ctgtgcttgt ccgccggttc caatcagcgc gccaatttta gcatcttctc
     7981 ttgcaagaag ttctgttgct gctccttgaa cagcgcctgt tcttaattgt gtcaaataag
     8041 taccatccaa acaagcggat accatacccg tttctggatc caatacgatc atcgttgctg
     8101 gtacacttgg taagtttttc ttgatgtttt caggatacac ggaaacgatt ttgacaccta
     8161 gcgcgccttc gccaccttct acataagcag gcatatataa gctttgtccg ttgctttttg
     8221 gcacatcgat attggtgcga agaggcacac ttgcctttcc tgctgaatac aatgacagtg
     8281 cttttttgtc cgcatcgatg gcttctctca ttgaaaaact tttgataata tcttcttttt
     8341 taagaaataa catttgaatc gctccttaat tagctgctgt aacttttttt aattgactgc
     8401 ccaacatcgt atatgcactg tatagtaaga ccaaaatcac gatccatttc aggatatagg
     8461 tatctaaaga tttgactagg aatacagcga ccaatacccc caatacaccg aaggttgaag
     8521 taaaaagtgt gatttttctg ctgtattcat taaatttaat gaattgaaca ctgccgatcg
     8581 gtactgagaa ggtacaagcc cccatcataa taggaaaggc tgcaactgga ttcaagccta
     8641 gcaagtagac agttaccatc gttaacgcat aagaaccaat gccgatattg ttcaatgcac
     8701 catagacaaa gagtaaaaat cctgccaaga ttaattttcc gccatacaat tcactggctg
     8761 ttccgtttga tggaatccag ttcatttgtc ctgcaaaaat caacaatgca gcaatgacca
     8821 atcctatgcc gacaaacagt ttgatcgttt tctctggtaa cttcacgaca aatcttggtc
     8881 ctaaatatgc accgataatt tggcagataa tacaaacagc tagtgtcttg atccctacgt
     8941 tgatggcagt gatgtaagac aatgccatga cggctaccgg tactacacat tgggtattca
     9001 acgttccggg tagttttttc atgctgaccc atttcaactt tggataaagg acggttccga
     9061 tagcaaagtc ggaaacgcca aatgttgaaa gaaagaagat gataaatgac gtgaagggca
     9121 acagacgcat atcccctggt tcttctttga aattttgttt gtttttgaaa aggtctctta
     9181 gaaagtaaat aataaaatat agattgattg cgacaattag tgtcagcaaa atattccgaa
     9241 tcataaaaaa ttcctcctac tagtaaatct ttctgattcc ctcaaagccc tcaccatatt
     9301 ttgctttaag ttcttcagga gattctgcaa tcacttttag tgtatatgca tcatgtttga
     9361 catattcttt tgctagattg accatggcgt ggttttttgt ccaagtgaca tcggttgatt
     9421 gcagttcttc gttaatggta ccaaacacga cttcttgctc atcggcgacg atgttgatcc
     9481 atcttgctcc aaagtcagca agtttgtctg tttcaaaacc atgaatataa tacttttcta
     9541 agggaagatc atattcatgg gtagaactga ataaaatcag tacaaactta tcaactcttt
     9601 tttcagcttg ctgcaatgcc tttagtagtg aatccgtgaa attctcatgc caaacttgaa
     9661 tgagcaaact ttcttttgcg tttttcacca aatgctctac tttatccaga acatactcga
     9721 taccatcaac tttccacagc atttcttctt catctttttc tttgatcatc cctagattct
     9781 tggtaagaaa agaaagatca tttttaacac ttttttctaa tttctctaaa aactcatttg
     9841 ccgagatggc atgataaagt ttaggttctg atttattaac gacaatcaaa ttctttttta
     9901 atagtttttc caaaatatta tatactttcg agcgtggcac acctgagatt ttacttactt
     9961 catatcctgt aagattacct ttttctaata gtgtggtata cactcttgtc tccatctctg
    10021 aaaaatcata ttttttcatg atttgaataa tcgtttccat tgattaatcc tcactttatt
    10081 tttagtagct actacggtaa caactataaa ttctttttga ttatctgtca agagttagtt
    10141 caataacaca catataataa ttagcttaaa aacaatcttt ttattaaaaa gaaacattat
    10201 aatatgaatg tttgtgaaaa aataatacaa cttagtcatt ctttacaacg atttatagaa
    10261 aaacaacctc tttaaatata aaaggtacgg gttactgatt acttgtaaat ctttacgttc
    10321 cagttttatt ctttctaaaa aatatactca cttcttttct tagacttctt tttttgattc
    10381 tcctctttat ggtcttgtcc ttttttgcct tcaaaatatt taaataaacc cctttcaaaa
    10441 gcatttctag gttttggaca ataaggaatg acttttttct tcatataaat acctcattta
    10501 actatttgat atcatcacat tatcaaaaaa aataggtttt ttattaaaac tatcttgacc
    10561 tttcgggaga tttcactgtg atttattttt attcccatac ttttttcgtt ggtcactttc
    10621 gtatacctaa tctaagcgat catcggcgac ggtgctttta caacgaatgg caggacaaaa
    10681 caaggggcgg aaaaactttt ttgcctattt cataaaaaac tttttcctac agcaatccct
    10741 tgttttgtcc taccacacgt tgtgaaccca aagcacgccg acgaacgctt agctatacga
    10801 aaatgacctc caaaaacaaa aaagtgaggt gaatagaaac aaaaagaaat tgaaatctcc
    10861 caaaatgtcg tccgcctcgg agacaacttg ctgctgaaaa tggttggtta attcatttaa
    10921 gtattaaata agataaatca tcaaattaat cggaaaaata gcatgattgg ccttatcaaa
    10981 aataaactgt aaaaacttat atttctatga gtggtggaac aatgctaata ccaaattaat
    11041 ttatcgatta cccacctgca caaaccaaag atagcattat taggaaacga atcaatcagc
    11101 gaatccagca ttataatgag gatactaaaa ataaagtttt cataattata aatccgcctt
    11161 cctacgaaag gcaccaatga ggtgatgaaa accttagagc gctttctttc tttttttatt
    11221 ccgtgttacc ctttccttgc aggtccctgg tacactacag aacccgagga ggtgagtggc
    11281 ggggctgtat agcggcaacc ccgcataatt atatggtgtc ggtcatccgt taaggcatca
    11341 atgaatggcg caaacccgta gcccgtaaac ttatctcttc cgaagttgac tcgatttcgc
    11401 cggatgacca gtccctacca aacctgtact atttttttac aggaggttgc tatgttcaaa
    11461 atctttcgta aaaattgttg tggcttggat gtccacaaaa cgtggatcta tgcgtgtatc
    11521 ggaatcacag atgcgaatgg tcgtacagtg tataagcaag ctcgcttctc ttcctttaca
    11581 aaaggtctca atgaattagc tgaatggctt gctaaataca actgtaagga tgtgtgtttg
    11641 gaatcttccg gtaaattttg gattcctgtt tttaatattc ttgaaaaaac ttgttttgtc
    11701 acactggctc atccgaagta caccaaaccc cagaaaggaa ataaaacaga tcgcaaagat
    11761 gcaaaaatgg atttgtgatc tctttatgtg cgacatgatc aaacccagtt ttattcctgg
    11821 tcttgaaatc cgccagcttc gtgatctaat gcgttatcgg acgaaactga ccaacatgaa
    11881 aacaagtgaa aagaatcgtg ctttaaactg cttaaccgtt tctaatctga aactagatga
    11941 tgtttttagt gatgtgttcg gaaaatcatc cacttctatc atccaatact tgttagaaca
    12001 tcccggtgaa tcatttgatg ttcgaccatt tatccatgcc cgttgtaaaa ctcccgttga
    12061 agaaatccaa gcggcagttg agggggcgat ttctgtacct caagcgatta agcttcgcca
    12121 atgcctcaac catattaacg agattgagaa gcatcgagaa gagatcaatc tagagattca
    12181 agctcttgca gaacccttct cccctgtttt ggaactactt cgtaccatac cgggcttaga
    12241 cactcagcca ataacagcga ttgcgattct ttcagaaata ggaccggata tgtccgtgtt
    12301 tccaacttcg aaacacttta tttcttgggc tggatgctgt ccaagaaacg atcgcagtgc
    12361 ccgacgaaca aaatcaacac gtatctctcg tgcagggcag tcgttgaaac cgctacttgt
    12421 acagattgcc aatgctcttc tcagatccaa agaacatcca gaatttaaaa atcgctatcg
    12481 tagaatcaaa gcgaatcgtg gacacaagaa agctatcatt gctatttgta agatgctcct
    12541 gaccgctatc tggaatgtct tatcaaaggt ggaaccctat tctgctaaag gatatctgga
    12601 gccaaaacct gcgaaagaag agaaagttct gacgcaatcc caagctctgg accttttaag
    12661 aaaacgcgga tataccatta tagatagtgc ttaaaccaaa gttacgttga ttcttcctaa
    12721 atagactcgt tgtcttccat ttcaaaaatt ttgaaaacgg taggcttatt tagtgtaccg
    12781 ttcttcaggt atcttcaaat agatttattt tcaaacttat ttcctttctt cttttactct
    12841 cctatagctt agcatttaag tgggcactcg tgtcaccttg ctagatagct atgaatgccg
    12901 taataagcct cctagtatat aggcagactg ccaattataa ctgattcaat ccacattatg
    12961 ataaaatcca ccttttcgtt tcatatgtgt tgaaatatca catatgtcaa aagtgcacga
    13021 gtcttttcat tcagtgcttt gtaaatactc aaaattattc cttttcactt taaaaaaaag
    13081 ataattagta caaaatcaga aatgaggaaa gtattaggat ggactagaaa ggagttgttg
    13141 aatttgttgc aacagattgg tcatttatca attaaaaatt aggtgaagtt ttattcatca
    13201 ctgcagctgc tgtttcccag agaataaaac gtctagaaga aactggtcag ttactgtatt
    13261 atcaagcagc aattgactac gaacaagctt gattactaac caaagcgttt atccacctgt
    13321 tgattaaatc aaatcaaaaa tcaggttttt atacgttcat aaaagcaatc tccagtgtac
    13381 tcgaatgtga ctgtatcata ggtccttatt cgatgttaat caaaatgggg tttccttcta
    13441 ccgaatcatt ggacagtttt atcaatgatt tatcaaagtt tggacgaacc aacacccaaa
    13501 tcgttttctc gactcttgtt tccttaatgg tttatcagtt ctggaatgtt tatcatgcgc
    13561 ttttattaaa atagaaaaga gcttttttca tgcgacaaag cagtgatcat ttattggcac
    13621 atgcaatctt tgtggatcca ttttttgaaa atacgatatt tagttttgac ccaaaaatct
    13681 ttaaatacgt atttgataat ttatcttaac aaccagataa ttttattcag caccgtatta
    13741 tctatattga attctcggaa tcaagataaa tttttttccg tttttgtttc ttttttaatc
    13801 ttcttcttgt tattaatagt gattaggatg atattcctat attgatcttt gataattaga
    13861 tataattttt gaataacgtt ccctgctatt cgagctagaa atacaagtac gccatgacct
    13921 agttagcgac aactacttag agatttcttt tgttctggga caacaaaatg ccatgacaat
    13981 agcagtaaat aatgatactt ccgtaaggct cgccgtaaac tggggagagg tgaaattcct
    14041 atgtgcttac ccaaagcggt tcaaaaattt taaactatta ttttaggaga tgattttata
    14101 aaatcgaaag cctacttgaa taaaaaacaa gcctgtgaat ttctaggaat tgataataat
    14161 actttagata agtggattcg tgtatataat tttccagtaa taaaaattga tggcgtagtt
    14221 cgctttgacg tagaggatat caaagatttc atgaatacat tcaaaaaaaa ttgaaatttt
    14281 cttctcgtca catatactat aaatagcgaa atgtactgcc ttacttttta aaggagtgag
    14341 gaagtttgcc tacaaagctt tcaaatggga aatataaaac taatctgagg tatccaaaaa
    14401 aattcagaga aatcactgga attgcatcag agaagtatca aaaagtattt ccaactaggc
    14461 aattagctat taaggccgaa agggaaatga aaaagaagat tgaaacagtt ttaagagagg
    14521 agaatgcaaa ctcactagaa ttgaaaggaa aaataaaatt taaagatttt tatgaatcaa
    14581 aatggcttcc tagatatgaa ctaggtcaaa ctactaggtc aaacagggct ccaagtaatg
    14641 taacaattag taatactaag gatatattcc gattgcacat ccttccaatg tttggtgaat
    14701 atgcaatgaa ttatctgaat tcaaatactg agataatatc agatgaatta acaaagaaat
    14761 cgaaagaata cgcaaatata aaaattatca aaggctatgt tcgctctatg tttgatattg
    14821 ccgaaatact atgttatatc gaattcaacc gaactaccaa aattattcaa tgtattaccg
    14881 cgcctaagaa aatggcttta gaagaaaaaa ggataaggga agggaatcaa gcattatcat
    14941 cagaagagct gactgattgg atagaagcag taaacaatga cttaaataat cacttgctta
    15001 cacttcacga ttacacactt ttcatgctta ccttatatct aggtgataga aaaagtgaga
    15061 cttatgctct gcaatggaaa tatattgatt ttaataaaaa tacggttcgt ctcaaatatg
    15121 ctttagataa atatcaaaga aagacacata caaaaggttg gaaagacacc gttattcagg
    15181 caccagaagt tgtgatgaca ttattaagag aatggaaatc agctcaggct gaacaattgt
    15241 tgaaactaaa aattatacaa acacctgacc agtacctctt tacctattcc aaaccttctg
    15301 gagaagtaaa ttgtcctgtt cacgctgact acttaaacta tcgaatcaat gcaataaaaa
    15361 aaaggcatcc tgaattggct caattatctc cacacaaact tcgtcatacc tatgcaacta
    15421 tagctaggga aggtggagca aatatgaatc aaatctctaa tgctttaacg cactcggata
    15481 tttctactac aaaaatatac gtgaacacac ctgacgtagt tgataaatct gtttttgaag
    15541 catttcaaaa aggattgaat aagtgtgatt aacatgtgtt ctcaaatgtg ttcttattat
    15601 aaaaaaagac actttccaaa taattgaaaa gtgtcctgaa atattgatat aaaaagaata
    15661 ttaacgtttt gagaattgtg aagctttacg agctttttta agacctggtt ttttacgttc
    15721 gaccatacgt gcgtcacgag taagtaagcc agcacgttta agagctaaac ggaagtcagg
    15781 atcaacttct agcaatgcac gagcgatacc atgacggata gctcctgatt gtccagcgta
    15841 tcctccgccg tttacgttaa caaatacgtc atatgcgcct tttgtttcag taacagcgaa
    15901 aggttgattg attacttcac gcaagtcagc atgtggaatg tattcttcaa catctttttt
    15961 atttacagta attttgccag ttcctggtac tagacgtacg cgagcaactg cgtttttacg
    16021 acggcctgtg ccgatatatt gaacttgtgc caatgaaatt ccctcctatt agattaagtt
    16081 tgtgatgtct aaaacttctg gttgttgtgc tgcatgtgga tgttctgctc caccgtatac
    16141 gttcaatttt gtaaattgtt tgcggcctaa agtgttttta ggaagcatac cttttacaga
    16201 agtttcgatc aaacgacgag aatttttagc acgcaattcg ccagcagtga ttgatttcaa
    16261 tcctcctggg tagttgctgt gacggtaata aattttgtca gtcgcttttt tacctgttaa
    16321 tttcactttg tctgcattga tgacgatgac gaaatcgcca gtatccaaat gaggtgtgaa
    16381 agttggttta tttttaccac gtagtacaga tgcaacaact gttgaaagac gtcccaatgg
    16441 aacatcagtt gcgtctacta cataccattt acgttctact tcgcctggtt tggccatata
    16501 tgttgtacgc acgttatttt cctccaattt aagttctgat gtttgacata cacttcgagt
    16561 ttccggggct ctttgtgggg caaacaatac catttaacat attacccgct aatctagtca
    16621 atgtcaacgt ttttctgctt gattgaaaaa tttatatgaa actttacttc ttttctttct
    16681 tttatataaa agggtcgttt cctgtcaaaa tgaaaaacaa aaagaggctg tgacaaaagt
    16741 cttgtcacaa ccccttattt tgaataaacg gtgttctcct gccaactcct cggtcacaag
    16801 tcacaatatc cataaaacat aagaagctgt tttttaaaat tgtttcttgt gactcggagc
    16861 tgaacggcag gcttacaacc tcttggtaaa cggtgttcaa tcagctgacc ctcggtatta
    16921 gctcaaaaaa cggcaaaata tgaggaacta ttttgacgtt tgtttctcta atactcaggt
    16981 caaaacgctg atttcacaac ctctttttcg gtcaagttca acaacagttt ttacgcgtcg
    17041 atctctggcg ctttgcccaa atgagcttgg atcatccaga tacgtttttc tgtggctgtt
    17101 ttgaattcga taaagatatc ttgtgttgga tcgtcgcctt cttctccaga aacttcgatt
    17161 cctttttggt aaagatctgc tagataacga tagcctgcaa caagtgtttc caaacgttct
    17221 ggaatagtac gatcccagcg gccaatttca tcagggattt ttgtgttatc tgcaaattca
    17281 cgcaatgtag aataaggtga accgtctaat gtgatcaagc gttcggatac ttcatctaac
    17341 tgagcgttca aatcatccat gaactcatcc atcattgggt gcaatgtaag gaaacctggt
    17401 cctctcatgt accaatgtgt ttggtgaaca acaacagaca tttggcttag atctgcaact
    17461 aattgattta atacttcttt ggtttgttgg aatttcatct ttcttgcctc ctaacatttt
    17521 cttacactta aaataatagt agactttcaa tgaaaagtac aacaaaatca tttacctgag
    17581 aacgattttc agttcgcttt tttatccgta aagccaatca tttttcagaa tcagctaatt
    17641 cttctcgcag ttgagcaaat tgctgataag tctgtgctaa atgcttttgt gtcgaaacaa
    17701 ataatggata gattttctga tattttttat gatcagtttc ttgtactcca acttgctctt
    17761 tcaattctat caattcctgt gcttcactga tactttggat ctttccgatg cttctccagc
    17821 ctaaaatcac agctcctaat gcggatgctt ctgtgacagt agggaaaaca agcgggtaac
    17881 ccagtacatc agccatcatc tgacgaaaaa tcggagattg agcaaacccg cctgtagcac
    17941 ggatctctgt gagctgattt tcctggcaaa ctccttttaa aatccgataa aggttgagac
    18001 agatcccttc tagaatcgcc ttcatcattt ctttttctgt atgttgccgc tgtaaaccga
    18061 taaaactgcc aaacgcatct gcgtcccaaa gcggtgctcg ctcaccaagt aaatagggat
    18121 gaaaaatcag accattggca cccgctggca caaaagcgat agccgaaagc agtgcatcat
    18181 atggattttc tcctttttct ttagcagatt gaacgacttc ctgtaaaaat gtatgccctg
    18241 cccaatcaaa gatgccagca ccattgctag tcgctcctcc cactacccaa tgtttctgat
    18301 ccagaacata acaaaacgtc tccatttctg gatggaactg aggctgagta gtaataaaac
    18361 gaagtgctcc gctcgttcct acggtcaaag cggcgatcgt atcaccaaaa gcacctaacc
    18421 ctagattaga aagcggcccg tctgcccctc ccaaaacaaa tgatatatca tttggcaaac
    18481 ctagttctgc tgctgttttt gatggtagac ctgttacttg ataggtggaa ggaaagactt
    18541 gcggcaattg ctctattcga atgttcaagt agtcaagcac ttcttctgcc cattggaatt
    18601 catggatatc aaaatatcca gttcctgaag ctgttccgta gtcgctgatc agttcgccaa
    18661 acaatctata aaagatatag tctttgatac cgacaaaata agcagttttt ttgaataatt
    18721 caggttggct gttttgcagc cacttgattt tgttcaatgg tgtcattgga tgaatcggcg
    18781 tcccagtctg ccgataaaat tctttgccaa gcacggtata tttcagtttt tctgcttcgt
    18841 ccgctgctcg gttatctgcc caagtgatca ttcgagataa cggtgttttc tcttcatcca
    18901 acaatatcag gccatgcatc gcagaggaga aggagacaaa ttgaatgatt gtgtctgaag
    18961 gcaactgttt aattacttct tttataacgg tgcagacacc ttgaaagatc aattcctgat
    19021 cttgttctgc catcccttgt gtttcttgga tcaaagggta gcgaaaataa gcggatgctg
    19081 cttcttgggc ttcatctgtg aaagcaactg ctttggtttg tgtggttccg atatctaatc
    19141 cgattgaaac gttcattttt tcacctcaaa ttttatgtat gtacaaaaat ttagtttaag
    19201 cttgcgtatc ttggttttga aaagggggag atggcgtgtt actttatttt atcattggtt
    19261 gctgtatcgg atcattttta tgtttaaccg cccagcggat tccgttaggt cactctatta
    19321 tttatcctag atctcattgt gtcaaatgct gtcgttcgct ttcttggtat gaattgattc
    19381 cgattctctc gatcatcgtc caacgatttc gctgccgcta ttgcaggtgt cggttgccct
    19441 tctactattt gttggcagaa gccttatgtg gtggtctttt tgcctggttc tttacttttt
    19501 cttccgcaag aaatttttcg acgttcatat ggatgctttc ggctttgcta ttttcgttga
    19561 tggatttatt ttacttcatg gtccattctc acacgctatt ctgttcttgg gcaattttat
    19621 ggattttttg gttgcaggcc ggcgtcttcc aatggcaaag tgtgctgtta acgtttatcg
    19681 taggcggtgt gtgccttcgc tatggtcaat cctatctcgg agctggcgat actctgttga
    19741 tgctttcttg gagtggtggc ttgtctctag aagagttgct tcagatcttg tttcttgcta
    19801 gtctgtttgg aatatccgtt ttttctgttt actttatctg tcataaaaaa aagttggaaa
    19861 agctgccttt cattcctttt ttgagcagtg cgttgctgat tgtccttcat cttaggtatt
    19921 gaaaaaaggt tgtgacaaac gacttgtcac aacctctgat atatagtgtt ctcttaccaa
    19981 atccttgtga cttggagcta ggcgacaggt tcacaacctc tccactaaat ggtgttcaat
    20041 cagctgaccc tcagtattag ctcaaaatgc tggttttaca acctctgata tacggtgttc
    20101 cataagtagc tttttcggct tcttatttct tgacgcccca atgtcgacga aggaaacctg
    20161 cacgtccaga accttctcga taaagattgt aatggagctt gtttttcttg taataatcct
    20221 gatggtaatc ttctgcagga taaaattcgc ttcttggttc gatttttgtc acgattggct
    20281 tatcgaatcg cccgctgtct tgcaatgctt gttttgaacg ctctgcaata tttcgttctt
    20341 cttcatcatt atagtagatc actggacgat aagaatcacc gcgatcagcg aactgtccta
    20401 atgcgtcagt cggatcggtt tgctgccaat agatttccac caactgatca taagaaataa
    20461 cttctggatc atattcgatc tctactgctt ctgtatgccc tgttgtgcct gttgttactt
    20521 gttcataagt tggatttggt acatgcccgc cagtataacc ggatgtcaca gaaatgatcc
    20581 ctggctgctc ttcaaatggt ttgaccatac accaaaagca tccgcctgcg aaaactgctt
    20641 tttttgtcat ataaaatccc ccttttttct catcatacct tgatttccaa aaggaggata
    20701 acgttttgct tgtgacagaa aaaacggaaa ctattatata cgtgatacgg cttctgataa
    20761 atgccaaaac gaacgtactt gatcaaaaac ggttaaatca ggaatcacat attcagcaga
    20821 aggaagattt atgttttcac ctattcccaa tacatgcatg ttaccagcca aagctgcttg
    20881 acaaccagct tctgaatctt caatgaccaa gcatgcattt ggcggtacat tcaattgctg
    20941 tgctcctttg agaaaaactt ctggatcagg ttttgctttt gatacttgcg tgccgtcaat
    21001 aaggacatca aaataacttg tcaaattcgt tttttctaaa atgaggcgtg catttttgct
    21061 tgctgatccc aatccgatct tgatgtttgt ttttttcaag tactcaagaa cagctattgc
    21121 accaggcaaa acggatgttt catccatttt ttgaatcgct tgaagatata gattgttttt
    21181 ttgctcagca aaggctgatt tctctttttc tgagaatttc tgttccattt ttccaaatga
    21241 cagcaatcgc tctagtgact cggttctgga tattcctttc agttgctcgt tttctttctc
    21301 agtgaatgga atggacagct ggttagctaa aaccagccac gcttcgtaat gataacgagc
    21361 tgtgtctaca agaacgccat ctaaatcgaa tagtgctgct ttgattttca tcgattacct
    21421 ccttgaaaat gaacgacttg aagtaaagat gcgatgtttt tagctgtgcg atgaagatta
    21481 tcagtggctt gctgtaaagc ttcttgtaaa ggcacagctg caggaaggat cggaaaaacg
    21541 gccgaaatgc caacatctgc tgctttttcg cttcctttac caacacttcc gcaaatagct
    21601 atcacaggaa cgccctctgg tactcttcta gcaatcccaa ctggcgcttt tccttttaga
    21661 ctttgtccat ctagacgtcc ttcgcctacg attacgaggt ctgcttgctg tacccgtatc
    21721 gaactccagt aaatccaata cgtagtcgat gccagagact attttccctg aagcaaatgc
    21781 taacagtcct gcacccattc caccaccagc actactgccc gatgcctcga ttacttgagg
    21841 ggcaaatctc atataaaaat catgcatggc ttggtcagcc actgctaatt cattttcttt
    21901 caagcctttt tgtggtccga aaacaaaaga agcgccttct tttccgcata aaagattagt
    21961 aacatcagta atgacagtga ttttggcttt aatcagctca ataggcacgt tcgttttatc
    22021 aactgtagca attttaccta gattttctcc cagtgcttct actttttgat tatcttgatc
    22081 gtaaaaagca taacctagac cttctgccat gccgatgccg ccatcgttgg tactacttcc
    22141 gccaacgccg atgatgatgt gtcgaacacc ttgttgcaac aattgtcgta tcagttctcc
    22201 tactcctcgc gtggataacc taagtggctg ttgttggttt agtgggacat ctttcaatcc
    22261 gacgatttct gccatttcaa aaatcgcagt ttgaccgtct gaagcgtact ggatttcttt
    22321 gtttttgcca aatgcattag taacgactgc tgtttgccgc ttcaacctta aactgtctgc
    22381 taatgatgaa accgttcctt ctcctccatc gcctataggt agcagatcat attcagcctg
    22441 aacaaaaact tcttgaaaac ctgattgaat ggcttgtgct gcctctaagg ctgtcagact
    22501 ttctttgaaa gaatctggcg caatcagaat acgcattatt ttcccctccg ttccaagatc
    22561 agttcttttt ccagctggta ttggtctcca ttgacaaaaa taggtaatgt ttctttcgtc
    22621 tcttttttta ttactatttg tttttttgtc aaaacaaata gcaacctgtg atttttccaa
    22681 ataaaaggaa aagaaatttt ttcccatgct gaaggaagtc ttggagaaat agaaagagtt
    22741 ccattcgtta ctgtaatacc tgaaaaacca aatataactg ctagccatag tgctcctaat
    22801 gaagcagcat gaattccgtc atctgatgaa tgcggatctg gtcctaaatc aatcaggcac
    22861 gcttcttgga ataaatgata cgcccattcc atttcttgga tacggcaagc ctctatggcg
    22921 tgaatcgctt tactcaacga tgagtcgtgg attgttttgt tttcatagta atgcaaattc
    22981 ttagaaacga ttggttgaga aaaatactca ggtaataagt ataacagcat gacaagatct
    23041 gcttgcttgc tgacttggag ttcatttact tcgctacggg cataatcaag taaaatagac
    23101 tggctgccag gacgttcttt gtaagtggtc aaatcaataa ctggcttact gagatacgtg
    23161 tcatcttgcg gaatcagctg ttctttgtta ggcactggca aatataactt atctaaaaaa
    23221 ttttgacatt ctttcaaaaa aagcggatcg ccagcttgat atttaacagc taaggccaca
    23281 ttataatgcg ccagatagtt cgtatatgca ttattgtcga tatattctgt gtattcatct
    23341 ggaccaatga ctctgtgtat ctctaaatga tcatcgactt ttacagctct gctcagccaa
    23401 aaagctgctg tttcatgaat gagcgttttt ccctttgttt ctaaaaacga ttgatcctct
    23461 gttgcttgga catactcttg aacggcataa gcaaggtctg cactgatatg atgttctgcg
    23521 gcagctgaag caacttcttg tcttgttccg gttttgatat tcaatgcagc aaatttgggt
    23581 gtctcttcct gaccagtgtg tgcgctttcc catgggaaaa gtgcaccttg atagtgataa
    23641 tctcttgctt tttgccgtgc gccttctaat cgatcataac ggtacagcag caaattcttt
    23701 gctacttcag gaaactgata taaaaagaaa ggcaggataa aaatttccgt atcccagaaa
    23761 acatgccctt tataaccttc gccagttagt cccttcgccc ctacactaac acttggatca
    23821 ttgcggggag tcataatctg taaatggtaa gcagcgaagt ccatcgctaa ctgatcgaaa
    23881 gaagaatcgc cttggatcgt tatccgatgc tgatgccaaa aatctgtcca ataagacatc
    23941 gactgctcta aaatttctgt ataactaacg cttttctggg cttgggcaat acttttctta
    24001 aacgggtctg tttgctgaag agaggtagag agcacgatga tcttctccag cgtaaaggac
    24061 gtattttttc tgatcttttc tgaaaaggaa gcggtgatcc ggcgattttt tgcttggaat
    24121 acacctgctt tattgaattt agctgcaatc ccaatatcaa ttttactttc tgttgtctgg
    24181 taggatgcac tgatcaaatc gtcaccaaat actcgcagtt ctttttcaac caactgctgt
    24241 gtaccaaaat tggtttgctg tccatcgata cccgttttca catctacttg gcagtcttcg
    24301 gtcaacggct tgatgaccac tttcagggct gcctgatgga gattattttg atcagcaaca
    24361 cgacaagtaa tgacttccac tttttttcct tgagcagttt caatgagcgc atagcgttta
    24421 agctctccca tttctaaatc tagtgcccgc tcgtatgcaa gaactttcat cgtctcaaga
    24481 gaaaaatgtt caccgtcgat ttttatttcc catctgatga catctgggag attcactaac
    24541 tcggctgatt ctgctcctaa aggtcggtta tatacaccag ctgcaaacat tccccttact
    24601 tgattccgat agtcttcctc ctggcttcct ctgataccaa aaaatccatt tccaatggtc
    24661 atctgactcg catacttatt gatatactct aaatcaaact gtttttcttc tactttcata
    24721 aggtaataac ttctcctgtt tctgccgaac gatataaatt ttccaccaga ttctggatga
    24781 catatccttg ccagccatct gcaatcatct gagtctggtc accgagcgcc cgattcacaa
    24841 aatgagccat acttagttca tgtgggtcat taactggcgt ggtcttttgt aaggaaacca
    24901 gctttccatc tacatcttcg aatagttcgc ctggatacag attagcacct gcctgatcgc
    24961 cacaaaaagc cacattcagt ttgtcttctc tgatattcaa agcaaacgaa gtattcagtt
    25021 ggatgatctt gccgttttct aattccagtg tgccaaaaat tgcatcttct actgtgaatt
    25081 tgcttggatc ccatttcccg aatttccctg aatttttttt cgtaccaatt ttttggaagc
    25141 tgtacgcccg aacgcttttt actttaggaa atccagtaat atacatcgct gtatcaagca
    25201 tgtgaatgcc ataatcgatc aaaggcccgc ctccttgaag ttctttgtcg ataaacgttc
    25261 cccagcctgg aacaccagac cgacgaagcg cattcgcttc tacgtaataa atatccccga
    25321 gaacatcaag atgattcttg atcattgttg cttcgtcaga aaaacgatgc tggaatccat
    25381 aagccaaaat ctgcccgttt ttatcggctg tctctgccat ctttcttgct tgatcagctg
    25441 tcatagctgg tggtttctcg cacatcactg aagcattagc ttcgagggca gccaatacat
    25501 gttcgaagtg aaagcgattg gctgtacaga cactcacgat atcgggagaa atctcattca
    25561 gcatttgtgt aactgatgta tacgcatgag aaaatcctgt acgtcggcaa aagtcttctg
    25621 ctcgctggct gactggatca accacagcgg ccaattctaa gacatctgat cttttttgat
    25681 aataagcagc atgtactttt tctgctactt gtccagcgcc tatgattgct actttcttca
    25741 tttatttctc tctcctttgc ttatttactt attgttattc tttctctatt ctttctctaa
    25801 atcatttaaa tgacgcgctg tttccagaca gtttttcaag tattgcaatg attcctgata
    25861 aattttcact tcattttctc ctcgcaaacg acattcatat accatataac cttcatactc
    25921 attttgaagt agcgtttgaa aatggcgagt aaaatcaatt gcgccagatc ctggttggta
    25981 gcgatgatta tctgctaaat ggatatgacc cacatactct ttttgcgtag tcaatgcttt
    26041 tgaaatatca tcttcttcaa tattcatatg ataaaaatca gcgatgatct gcacatgttt
    26101 caattgatta gagtcaatgt aatgacgcgc atccgctaac aaattgatca tatggtcttg
    26161 gtatcggttc aaaggctcca aataaataac cgtacctgtt tcttcggcta ctttatctaa
    26221 ataacgaagt gattcgctga ctgctttata gtctccttct ttgcttcggg gtgaaaccat
    26281 cggcggtaat cgataagtga acattcccca agctgctggg ataacgattc ctttgcctcc
    26341 aacctcgctt agtgcacgca aaatctcagc aatttgacgt acaccattaa gacgccgttc
    26401 ttcgataaag tcaccgatcc acccatcgta gccgttacaa gctgtcacta ctgggatccc
    26461 tgtttctttg attgcctgtt tgactgtgtc gatattttct attaacaact taccgtcgat
    26521 ttcgtattct tcaaatccac agtctttgat aaatctaaat ttttctaaaa tgtctcttgg
    26581 gaaaaatgct tgatcttgcg taccgaattt cattgttctc ctcctcggac ttgaacgccc
    26641 attttgatac tttcttctgg gtgctggtct acataacgca tgtaagcttc tgcgctttct
    26701 gcaaatggca caactggatc aatgatttct tcacaatcca agtaaccgtt catcaataat
    26761 tcccaacatg tgtcctcgat tcgtttacgg ttccatcttg ggtaatctgg gtttggttca
    26821 ctagatgctc gagcaaagac gatttttgca ttattgaaat gtgcttcgcg accaagatta
    26881 aacccagctg gaaaaggttt agcaaaggca acataagaaa tgatcccgcc atagccgatc
    26941 cctcttaaag aagcttgtaa tgcggcagca ctgccactcg tttcaataac tgaatctact
    27001 ccacgtttat ctgtcaattc ctttagacga aaaccgacat ctgctttcat aggatctagc
    27061 gtgtaatcgg caccgtattt ttctgctaat tctctacgct gcgctatggg atcgatccca
    27121 acgatggtag tagcacctgc ttttttagct aattgaatcg caatttgccc gatagcgcct
    27181 aaaccgaaga ttgctacagc atcacctgct cgaacatgtg cttcccggat accacctaaa
    27241 gcgaattgag caggatcgta acatactgca tttttccatt gatccaaccg atcaagttta
    27301 cgtagtttat aattatcaac accgtttgta atcagcgttt cacgaatggg tccataagtg
    27361 cagactaact ctcctttttg atactctgtc accaaactgc ccgtttcttc gatcgtaccg
    27421 acaatcatat ttcctaattg aaattcgcca aataccacac cgcgttggct tccttcttct
    27481 cttggcaaga ataggcgcca ttcttctgaa aattcttcat cgataaatgg acttaatcct
    27541 ctaaagtcga caatttctgt tcctggtttt ggagtagcga aaattactcg gatacgtact
    27601 tcgttctttt cgatctcacg gtcttcgtaa tctttgaatc cggctattct tggttctaat
    27661 gcaactaatt ttttcatctt ttctttcctc tttcttttct ttttatcctt ttacgccgcc
    27721 ttcgactaaa tcacctttaa taaatcgttc agataacgca tacataatga tgactggtaa
    27781 agcggtcacc aatgaagcgg ccatcattcg tccccaaatg tagtctggtg tactgaataa
    27841 tgtgttcaaa ccgattggta aagtaaattt ttcggaggtc gacaggaaaa tcgaagcaaa
    27901 taaataatca ttccacgaaa ccataaagca ataaacgaag acagaaatga ttccagaaat
    27961 agccaatggt ataatgatcc gaataatgat ctggatccgg ctaagaccat cgatcattgc
    28021 tgcttcttca atatcagtcg gaatcgtgtc aaaataactt tttagcatga atatcgcagt
    28081 aggaagtgtt tgaacgacca tcgtgataat cagtgctgta ttggtatcat acaaacctag
    28141 accggaaatg attttaaata atggaacaac gatcaaaata ccggaaaaca tataaacggt
    28201 gtaaaagcta gcattgattt tcgagcgagc tttgaagcgt agttttgaca aagcgtatgc
    28261 cccgctgatc ccaatcacta ctgcagttac ggaggctatc aaggagatca ctaaactatt
    28321 tttgaaatac atgatgaatg gaaaaatctc agcattgaaa atatcctgat aatgttcaaa
    28381 agtccattct ttcggaaaaa tagtttgtgt cgttgcaatt gcttcttgtg aatccttgaa
    28441 tgatgtcatc agcatgatca aaaatggaaa caaattgaca gctaatagca acaaaatcgt
    28501 cgcgtaaaat aagattttcc tgctcttttt atttttcatt tcaagtccac cttctttcgt
    28561 gagagcaaga cgaccgctgc aataatgatg aacaatagaa tcgatatagc tgctgctttt
    28621 ccaagatcat tgaacgcaaa ggctgtctga tacaaataaa cgcctaagat attgacttta
    28681 ttcgtcagta gatagacatc tgtaaacata tagaacatcc agatagatcg taaaacaatc
    28741 acagttgcta gtactggttt gattgccggc agtgtcacga tcttgaactt ctgccaagca
    28801 tttgcaccgt ccatttcagc tgcttcataa agcgttttgt cgactgtttg caaaatagcc
    28861 aaaaatgaaa taaacgcata cggatagtat ctccagatag caaacaaaac gaccataaag
    28921 aagctagcaa ctggctggtc gaaccacagc ggtgcttcgt tgaaaagctg caacctatct
    28981 actaacagat cattgacgat tccataacta ttattgaaca tatatttcca agcaaaaatc
    29041 aaagaaatag atggcgtaac ataacttaat aaaatcagtg aacgcaccgt tttcctaaat
    29101 ctgaacttgc ggttaagcaa aatagctacg gctaatccta aagctgtact gcctgctaca
    29161 actaagaatg tgtaagcaac tgttaaacct aaagaacgat aaaattcact atcacttaaa
    29221 atttcaagat aattgcttaa tccgataaaa acggcgtctg agttaggatt cagcggcata
    29281 tcgaaaaaac tgatctgaat attggaaagc attggaatca gcactaaaac agctaataaa
    29341 agcatgcttg gtgctaaaag tcccatggct aattttaagt cagaatgttt ccttggacga
    29401 ttcattgaaa cctccccctg ataatctgcc aatagctatc tacttttttc gaacaccatt
    29461 ggcagaactt cttgttattt cgtatttttt tgtgcgtcag ctaaagcttg atcgacatct
    29521 tcgtttccga cagttacttg gttcactgct tttccgatca cacctgagct tgtgatatct
    29581 cccattttcg tgaaattctt ttccccgact agtccaaaga cttgtacttc atcaaaagca
    29641 ctagcaatct cagatggcag ctcgccaaaa gacttgatga cttcattttc tttgtaacca
    29701 tccagttcga ctacttgttt attcactggt tgagcaccac caggagacat caagacccac
    29761 ttttccatgt ttttcggttg agataagaaa gctgtgaatg cttcagcagc ctctttttgt
    29821 ttctcgtcta gaccagaaga aatcgtcaat ccagatactg tgccatagac agcttgatct
    29881 ttttgtgttg ggatagcaaa accgatattt tctgagttcc ccgcttcata aacagaaggc
    29941 aaaatgtaag ttgaatagat tgccattggt gctgttccat tcatgaaagc atctttgatt
    30001 tctgtcacat cattagagcc tggcatcgtg tattgggata agttttgata aaacgacaat
    30061 gcttctctca tcttttccgt atcgatcgtt acctcgcctt catcatccaa aacatttgct
    30121 ccatttgaca aagcaaattg agagaacgct tgctcactca ttgttccttc agcagtaggc
    30181 atagcaattc catattgttt attctcttta tctgtgaaat gttgagcaat ttttaaaata
    30241 tcatcccaat tttctggttc tgaaaaacca gcttctgata atttttcttt gtcataccaa
    30301 ataccttgaa cccagccgct aattggtgca gcaatatagc tttttccatc ttctgaacga
    30361 acaaggtttt tggctccgtc ataataatta tcttctccag cttcctcgat aacgttttgg
    30421 actgccgtct gatcaatcag ttcatcttta tccatcactt tagcaaaatc ctgactgact
    30481 tccattactt ctggtaattt accggaacga gctaacgtaa cgatttttgt attgaacgct
    30541 gattcttcta ccggcacttg cttgattttg atgtctggat tttctttttc aaaatcagca
    30601 accagttcat tgatcacact taatcgttcc tgttcgacag aagagtgcat gaattgaatc
    30661 gttgtctgtt gtgattcgtt agagctttga ctttcaccac aagcagtaag aagaaatcca
    30721 gtagctagca gacaggtagt aacaataatt tttttcattt ttttccacct cttattttat
    30781 tattttcagc cacatatatt catacggctg gaatatcaac tttcgttctt gactgcaatg
    30841 gataatttgt ccagaaaaca ggtctaggta atctcctttt ggtaaaagat aacctgctga
    30901 ttgattggaa aaattatgga taactaagac tttctcttcc ttcgcttcgc gaataaaact
    30961 gataaaagaa tctgctgagt ccagtaagta aatcaaacta ttcggatgga aggctttttc
    31021 tttttttcga atagatagca tctgggtcaa ttcaccatat actgctgttc ttaatggatc
    31081 tgtctgcaac tctttctcaa tatctgctaa caaaaatttt tgccgattga tttttcgatt
    31141 ctctcctgtt ttttctacgc ctttgtaatc atttcgactt cccagcacac tttgaatata
    31201 aattgccggc acgcctggta acgttaccaa aaatgaatga gcagctaaaa agcgtttgct
    31261 tctccattcc gtcgtatctg ttggagaact taacgcatct agatacgtag cgtttatctc
    31321 atatggactg gtcgttccat ctgggttttt cttgtagttt actcgggcac cctctttctt
    31381 cagctgttcc actaattcaa ggatcgtttt ttccggcaga atacctcgta ccggattcaa
    31441 tccgataccg tcatgggagg ctaaaaaatt aaaaaaagtt gtttttttcg atgcgaaatc
    31501 gatggttttt aaccattctt tcaacttact tgtattaccc gaacgaatcg cttgaagggt
    31561 caaaggtggt agcgaaaact gatagaccat ctgtgcttca ttctcgccat tcccaaaata
    31621 actgatatta tctttgtgtg gcacatttgt ctcagtgatc aataccgttc ctggagctgc
    31681 ttcatcagcg attgcacgga ataattggat gattttatgc gtttctggca ggtgtataca
    31741 agaagttcct agttctttcc ataaaaatcc cacagcgtcc aagcgaataa atgaagcgcc
    31801 tttttctaag taaaacaaaa gaatatcgat cattttcaat aaaacttctg gatttttaaa
    31861 attcaagtct acttgatctt cgctaaaagt cgtccatacg tgtttttctt tcccgttttt
    31921 gtcaatgaac gttgtaagta acgggctggt ccttggtcta gtcacgctgc ttgtatctgt
    31981 atccagtggc aaatcaataa aaaaatcttt gtacgtatca ttcaagttta aatattcctg
    32041 aaaccaagta ctttcggcag acatatgatt gcagacaaag tcgaacatta accgtgtttc
    32101 gcttctcatt tcttctatat cttcccatgt gcccaaacgg tcgttgattg cctgataatt
    32161 tacaacggag aaaccatcat cagatgtata tgggaaaaat ggcaagaaat gtacaactct
    32221 aaatgtatct gccaaatact tttgataaaa tttcttaaat gtacgcaaag ttggttgctg
    32281 ctcttcaaaa aattgatccc cataagtaat caagaaaata tcttcttcgt cccaatgcag
    32341 tttgcctgcc tggcctttct tctgctgata aacactgact ttttgttcaa tcatagaggc
    32401 ggttttctca gacaaatctg agtcgcgata aatcgcttgt aaaagttttg tatacatcgg
    32461 attccccttt cttttttggg agcgttccca acgatttgat catattatgg aaaacgctta
    32521 ctgtcaatag cattttttta aataattttg atatacacaa aaatacaaat aagaaagctt
    32581 atgtatcaat aattaatagc ttcttaaaaa aatatggtct ctcatgatca tgcaagctat
    32641 tcctaaattt tcaaaatcat agacaaaaaa gaatgtctat tgtactatgg aattattcta
    32701 aaacgctccc aaaaaggagg tgcatataaa attgaaacct actatttatg acattgcgaa
    32761 aaaagctaat gtctcaaaat caactgtctc cagagtatta aataaccagc caaatatctc
    32821 tgataaagca aaagcaagtg tacttcaagc aatcaaagaa ttgaattatg aaccgagcaa
    32881 aattgcaaga ggactgtcag gaaatggttt tgacgcgatt ctagcattat ctcatcgtac
    32941 ttctcatacg acctatggca atcctttttt ttcagatgtt attcaatcca tttctgccgt
    33001 ttctgaacaa aataacttcg acttgattct acaaacggca aaaacaccag aagaagagct
    33061 agaaaaatgc gcgaaaaaga tccaagaaaa aatgatccga ggaattatta ttttaagctc
    33121 tacgatggat gaaacacttc tttttgaatt ggatcaatac aatattccta ttgtggtaat
    33181 cggaaaagtc ggaaacgact acacgaacat ctactcagtg gacacggata atttccagga
    33241 tagttacgat ttggtggaaa cactgatcaa gaatggacac cgtcatatcg gctgtctcca
    33301 tgctccgaca gaagtttatg tatccaatga tcgtctcaat ggttaccgtc aatgcttatt
    33361 tgatcaccac ctagatatcc gtaatgaatg gattatagac ggcggctttc gcttagaaga
    33421 tagcatggca gcaatgaatg atttaatgaa gctacgagaa agaccaactg cgattttttc
    33481 taccgatgca ttaaaatcat tgagtattta caaagtggca gaacaatctg gaaagcagat
    33541 acctgatgat ctttcgatcg caggattcag tgatccctta ttgtcctccc tattttcgcc
    33601 acagttgact cggatagaca ttccgacaaa tcagttagga atcaaagcca cagaactttt
    33661 attccaacta atccaccacc aataccctga agaaaaaaga atcattcttt caaccgagat
    33721 tactctcaca gattcgatcc aacaacaaga aatgtagaac agaattataa aagaacagaa
    33781 acactgagga taagtcagtt actctgttct tttttcaatc actcatccct cgttaccccc
    33841 tcccggtatt ttagcgaatt tttcttattt tccatctgtt ttagatagct gtggataact
    33901 ataatgtttg tgttaaacta ttttttccac agggaagaaa aaactatttt taaccacgtt
    33961 gtgtataagt ttttatagtt cgttttttta aacacattta cccttatttc aatccatgtt
    34021 atttggggat acttatctct aaaacataaa tagaataaca gacatgtcta ctggttttgt
    34081 tttattcgag gaattattca ataatagcta gcaaaatatt aaaaataacc gctctatctt
    34141 cccatcaatt tattttgcat tcaaaaaatg atctatcttt acttttgttg attgacttct
    34201 cttggaagat gatcgttccg ataccttaat tggatacgaa ccgatgttgt taagatcctt
    34261 tcccactttt cttctagtta gacaaattat tttagacaaa ccaaaaaaga ggttgtgaca
    34321 ataatttgtc acaacctctt ttttaaaata tctattttgt ttgattgttc attgcgtctt
    34381 ctgcagccat ttgcgcttca atatctgaaa tactgtagac attttcgctt gctacaccga
    34441 cttcttttgg ttccatgtca cgataacgtt gcataccagt accagctggg atgatcttac
    34501 ctataataac attttctttc aaaccaagaa gaggatcttt cttaccgcgg atcgcagcat
    34561 ccgtcaagac acgagttgtt tcttggaatg atgcagcaga taagaaacta tttgtttcta
    34621 atgatgcttt tgtgatacct agtaagacag gtcgagaagt tgcaggaacg cctcctgaga
    34681 ctagcgtatt gtagttttga tctttaaagt ctgcgatgtc taataatgta cctggtaaga
    34741 tatctgtatc acctggatcc attacacgaa ctttacgcag catttgacga accattactt
    34801 cgatatgctt gtcgccgatt tctacccctt gcatacggta aacacgttgt acttcacgaa
    34861 gcaagtagtt ttcaacagat aatacatcgc gaacttgcaa caattgtttt ggatcgattg
    34921 atccttctgt caatggtgca ccacggtgga tcatatcgcc ttctgctact ttcatacgtg
    34981 ctgtataagg aacagtatac gtacgtgtat ctgtttttcc tttgattgtt acttctttgg
    35041 tacgtgttgc aggatcttct gagatatcga tgacatcccc tgttacttct gtgatcactg
    35101 cttgcccttt cggattacgt gcttcaaaga tttcttggac acgaggaaga ccttgagtga
    35161 tatcgtctcc ggcaacccca cctgtatgga atgtacgcat cgtcaactga gtaccaggtt
    35221 caccgattga ttgagcggcg atcgtaccaa ctgcttctcc gacttcaacg tcagagccag
    35281 ttgcaaggtt gcgtccgtaa caatgtttgc agacaccatg ttttgtatta catgtgaaga
    35341 cagaacggat tgtcactgtt tcgacacctg catcaacgat ttgttttgcg atgtcttcgg
    35401 aaatcaattg gtttcctgca atgatcaatt catttgtttc aggatgacgt acttctttac
    35461 gggtgtaacg tcccactaaa cgatcttcta atgattcgat gatttcattt ccctcgcgga
    35521 tggcttggat ttcaagacct cggtcagtac cgcaatcttc ttcacggatg attacatctt
    35581 gggccacgtc aaccagacga cgagtcaagt aacctgaatc ggcagtcttc aaggctgtat
    35641 cggtcatccc tttacgagcc ccgtgagttg agataaacat ttccaagacg gatagtcctt
    35701 cacggaagtt cgaaatgatt ggcaattcca tgattcgacc attaggagcg gccatcaaac
    35761 cacgcattcc ggcaagctgt gtaaagttgg aaatgttacc acgagctcca gaatcagaca
    35821 tcatgaagat tggatttttc gcttccaaac cttccatcag tttttgttgg atgctgtctt
    35881 ttgcagcatt ccaaacagca atgacacgtt cataacgttc gtcatctgtg atcagaccac
    35941 gacggaattg ttttgtaata gtttcaactt gtttatgggc attttcaatg atttcttgtt
    36001 tttcattcag tacactgatg tcagcgatcc ctactgtgat accggcatgt gtcgaatgtt
    36061 tgtaccctaa gtctttcata cggtcaagca tcttagaagt ttcttttact ttgaatcgtt
    36121 tgaagacttc tgcgatgatg tttcctaagt ttttcttctt gaacggtaat actaattctt
    36181 gctctttgat atgtgcagga atatcagtac cagcttcaac aaagtatttg tccggtgttt
    36241 ggacggtcaa gttgaagtct gttggttcat tcagataagg gaattcagga ggcatgatct
    36301 cgttgaagat gatcttacca actgttgtga tcatcgtacg ttctttttgc cattcagtaa
    36361 atggtttttc acctaatgag ttagggttca caccgatacg tgaatgtaaa tgaacatatc
    36421 cgttgcgcca tgcgataacg gcttcgtttt gatctctgaa gaccattcct tcgccttcgc
    36481 gtccttcttc ttccattgtc aagtagtagt tacctagaac catatcttga gaaggagtaa
    36541 caactggttt accatcttta gggttcaaga tgttttgagc agctaacatc aacatacgtg
    36601 cttctgcttg tgcttcttca ttcaatggaa cgtggacagc catttggtct ccatcgaaat
    36661 cggcattata agcttcacat acaagtggat gcaaacggat tgcgcgtcct tgtactaaaa
    36721 ctggttcgaa tgcttggata ccaagtcggt gaagcgtagg tgcccggttc agcaatactg
    36781 ggtgttcctt gattacgtct tctaaaacat cccatacttc gtcttcttga cgttcgattt
    36841 tacgtttcgc atttttgatg tttgaagcta gttcgcgttg aacaagctca cgcatcacga
    36901 atggtttgaa taattcaatg gccatttctt ttggaagtcc acattggtac atcttcaaga
    36961 aaggtccaac aacgataacg gaacgacctg agtagtcgac acgtttacct agcaagtttt
    37021 gacggaaacg accttgtttc cctttcaaca tatgagaaag agatttcaat gggcggttac
    37081 ctggtccagt aactggacgt ccgcgacgac cgttatcgat caatgcatct actgcttctt
    37141 gcagcatacg tttttcattt tgaacgatga ttccaggtgc attcaagtct aacaaacgtt
    37201 tcaaacggtt attacggttg attacacgac ggtaaagatc attcaagtca cttgttgcaa
    37261 aacgtccacc ttctaattga accattgggc gtaaatctgg tggaataaca gggataacgt
    37321 ccataaccat ccagcttggt tgatttcctg aagcgcggaa tgcttctaaa atatccaaac
    37381 ggcggattgc acgtgtacgt ttttgtcctt gtgcagattt caattcttct ttcaattcgg
    37441 ctgcttctgc atctagatca acattatcaa gtaattgttt aatcgcttct gcacccatag
    37501 cagcttggaa ttcttgtcca tattgttcac gtttttcgcg atattcgcgt tctgtcaaca
    37561 attgtttttt ctctaaattc gtatttcctg gttcgatgac tacatatgaa gcaaaataaa
    37621 tgatttcttc caaagcgcgt gggctcatgt ctaatacaag acccatacgt gaaggaatcc
    37681 ctttaaagta ccagatatgt gaaacaggag ctgctaattc aatatgtccc atgcgttcac
    37741 ggcgaacttt cgaacgagta acttccactc cgcatcgatc acaaacgatt cctttataac
    37801 ggatacgttt gtattttccg caggcacatt cccagtcttt tgtaggacca aaaatccgct
    37861 cacagaacaa cccttcgcgt tcaggtttta aggtacgata gttaatcgtc tcaggttttt
    37921 ttacttcacc gtaagaccag cttctgattt tttcgggaga agccaaacct atttgcatac
    37981 tttcgaattt atttacatcg atcaaaaggg gttccctcca tttcatttaa tggcaaaccg
    38041 caagacggct gatcttcgac cgccttgcag ctcatagacc ggattagtct aaattatctt
    38101 ctgcggtttc aaagttttgg atgacatcgt ctttttcatc ttccacttgt tcagcagctt
    38161 tcttttctaa ttctttggca gtttgctgtt cggcaaattt tgtcaaagca tcaacagtga
    38221 tcaaatcgtc gtcttcatcg tccatgtcgc gaagttcgat ctctgtttct tcgatatcca
    38281 agacacgcat gtccagacct agtgattgca attctttcac caatacgcgg aatgattccg
    38341 gtacacctgg ttttggaatt ggttcaccct tgacgattgc ttcgtatgtt ttcacacgtc
    38401 cgactacgtc atctgatttg tatgtcaaga tttcttgtaa agtataagcc gcaccgtaag
    38461 cttccagtgc ccatacttcc atttcaccaa aacgttgtcc accaaattga gctttacctc
    38521 ccaatggttg ttgtgtaacc aatgagtaag gtccgattga acgtgcatgc aatttgtcat
    38581 cgaccatgtg agcaagtttg atcatgtaca tcacaccgac agacacacgt ccatcaaatg
    38641 gttcacctgt acgtccgtcg tacagaacag ttttcgcatc gctggccata ccggcttcac
    38701 gaactgtttc ccatacgtct tcatcacttg caccatcaaa tactggcgtt gctacgtgga
    38761 tacctaactg acgtgcagcc atacccaagt gtaattccaa tacttgcccg atgttcatac
    38821 gtgaaggcac ccctaaagga ttcagcatga tatcgattgg tgttccatca ggtaggaatg
    38881 gcatatcttc ttccggcata atacgggata caaccccttt atttccgtga cgaccggcca
    38941 ttttatcccc ttcatggatt ttacgttttt gaacgatata aacacgaact aacatgttta
    39001 cgcctggtga caattcatct ccagcttcac gagtaaagat tttcacatcg tgaacgatac
    39061 cgccgccgcc atgtggtaca cgtaatgatg tatcgcggac ttcacgagct ttttcgccaa
    39121 agatcgcatg caatagacgt tcttctgcag ataattctgt tacccctttt ggcgtgactt
    39181 tccctacaag caaatcgcca tcttggactt ctgcaccaat acggatgata cccatttcgt
    39241 ctaaatcttt taatgcgtct tccccgacat tagggatttc gcgtgtgatt tcttcaggtc
    39301 ctaattttgt atcgcgggct tctgattcat attcttcaat atggatagaa gtgtatacgt
    39361 catcttttac caaacgacgg ctcatgatga tcgcatcttc atagttgtac ccttcccaag
    39421 tcatgaaacc aactaaaacg ttttggccta gagccatttc gccttgttcc atagatggtc
    39481 cgtctgccag agtatcccct ttttcgactt tctcacccaa atgaacgatt ggacgttggt
    39541 tgtagcttgt tccggagttt gaacgacgga attttgttac atcgtattta tctaatgcac
    39601 cgttgtcgcg gcgtacgcgg atttcagaag catcaacgta ttcaacgaca ccatcatgtt
    39661 tacataacaa agcagctcct gagtcatgcg ctgatttgta ttccatacca gtaccaaccc
    39721 atggtgcttg aggattgatc aacggcactg cttgacgctg catgttggca cccatcaagg
    39781 cacggttgga gtcatcgttt tccaagaaag gaatacatgc tgtcgcaacg gcaactactt
    39841 gtttaggtga tacgtccatg tagtctactt tatcaataga tacttctaag ttttcacttt
    39901 gagcacgagc cataacaacg tcttgagcaa atgttccatc ttcattcaat gggctgtttg
    39961 cttgggctac gatgtaatgg tcttcgatat cagctgtcaa gtagtcgatt tggtcagtaa
    40021 cacgacctgt ttcacggtct acacgacgat aaggtgtttc gataaatccg aatttattta
    40081 ctttcgcata actggacaaa ctattgatca acccgatgtt tgggccttca ggagtttcga
    40141 tcggacacat acggccatag tgggagtagt gaacgtcacg aacttcataa ccggcgcggt
    40201 cacgagtcaa tccgccaggt cctaaggcga aaagacgacg tttgtgtgtc aattcgccaa
    40261 gagggtttgt ttgatccatg aactgtgaca actgagaaga accaaagaat tctttgatac
    40321 ttgccacaac tggacggata ttgatcaatt gttgaggtgt caatgtttca gtatcttgga
    40381 tcgacattct ttcacgaacc acacgttcca tacgtgctag cccgatacgg aattggtttt
    40441 gtaaaagttc accgactgaa cggatacgac gatttcctaa gtggtcgata tcatcgacat
    40501 tgccgatacc ttccatcaag ttcaagaaat agctcattga agcaatgatg tcggctggac
    40561 gaaccgtttt tacagctgct tctggatagc cgtttccgat cacgtttact tcacgttcag
    40621 ggtctcttgg tgaaaatact ttgatgactt ggacagtcat tggatctgtg accacaccgt
    40681 cttctgatgg atagtaagtc actgaattta ggccattatc aatgaaagga gctagtgttt
    40741 ccatgacttg gtgagtcaga actgttcctt tttcaacgat gatctcgcct gtttctggat
    40801 caactaatgt ttcagctaat gtcagattca atagacgtgt tttcaaatct aattttttgt
    40861 ttactttgta acgaccaacg tttgctaagt cgtaacgttt tggatcgaag aaacgagcat
    40921 tcagcaagtt acgtgagctg tctgctgttt ttggttcgcc tggacgcaaa cgttcgtaaa
    40981 cgtctttcaa accttcttct gttcttgagt cgcttgcgtt tttatgcaag tctttttcga
    41041 ctgtattgcg taatgtttcg ctgtcgccga agatttcaaa gatcgtatca tcggaaccaa
    41101 atcctaacgc acgaactaat acggttaaag gaatcttacg tgtacggtcg atacgtacat
    41161 aagagatgtc ttttgcatca gtttccattt ctagccaagc tccacggtta gggataacag
    41221 tagaaccgaa tccttctttt ccgtttttgt cgacttttcc atggaaatag acacctggtg
    41281 aacggactaa ctgagaaacg attactcgct ctgccccgtt gatgatgaat gttccttgtt
    41341 ctgtcattaa tgggaaatca ccgaagaata cttcttgtgc tttgatttcg ccagtctcgc
    41401 ggtttgtcaa acgcaatgtt acatgtaatg gtgcagagta gtttgcatca tgcgcacgag
    41461 cttctgctac tgtatacttt ggttctttca attcataatc tacaaattcc aaagatagat
    41521 tgccattgaa gtcatcgatt ggcaaaatgt cttcaaacat ttctctaagt ccctcatcta
    41581 agaaccattg gtaagagtct gtttgaattt cgatcaaatt tggtaattcc aacacttcac
    41641 tgattcttgc gaaacttcta cgttcgcgat gttttccgta ttttactacg tgtccagcca
    41701 agctcttcac ccctctaaaa tgtcattcaa aaagactacc cgatcaattg ttacaataat
    41761 atttcaaata ttatttttag gtaacaacag acattttttg cggcttttag gcaaaaaaaa
    41821 accaaaaata gaacattctc ttgaaacctt acttcgtgag cttctacttt tgtttcctta
    41881 tattaaagcc gaaacggaca atatttcgtt tctgcctttt cttcatcaga tagtttttgc
    41941 aacttcatat actacactta ttttctataa aagtcaacac ttcctggcgt ttcttctgct
    42001 ttttcgcaac attttcttaa tgttttcaat tttatgtttt caattatctg acaattctta
    42061 attgacagac ctttttatct cggttatact ttagaaaatt cattttgtgg aggaacttct
    42121 atgcgaacca acatcaacca aatcgcacca acacaactga ataactttta ctttagctac
    42181 tttagatagg tttgtattca tcatgatgga tacaaacgtt aaacgacagt ttgtatctat
    42241 gatggctaaa gaactttgta ttgcagcaaa aagccacgta gacaaaatgc taagtggctg
    42301 agcagtgaaa atacaaagta aaagtatcaa gcattctact ttttcaattt attttccgac
    42361 ttttcaatcc atttggacat tttgtctgaa tggatttttt gtttcccaaa attaaggagg
    42421 aaaaagaaat gaaaaaaaat ataatcatcg gattaggcgc tgccctgcta ctagctttag
    42481 gaggttgcgc acaaaaagac aattccgcag aggcatcaga tggacaaaaa acaattggcg
    42541 tattgcaact tgtacaacat aactcgttag atgctgccta taaaggattc aaagaaggat
    42601 tagcagaaga agggtataaa gaaggcgata atctaacaat cgattatcaa aatgcccaaa
    42661 acaatcaaga caacctgaaa agtatgagtg agaaactcgt caaagaagat cctgatttgc
    42721 tacttggaat cgccactcca gcagcacaat ctttattaaa tgaaacaacc actatcccga
    42781 tgactgtcac agcggtcaca gacttggaac aagcccattt agtcacatcc aatgaaaaac
    42841 ctggcggcaa tgtgactggc acgacagata tggtgccaat cgaaaaacaa atcggcttac
    42901 tgttaaatat cgtgccagac gccaaaacaa tcggcatcat gtataacaac ggtgaagcaa
    42961 actctaagat ccaagctgat ttggcagaaa aagaattgaa aaaagcgggc gtcaaagtca
    43021 aagtactgac agcaaattcc acaaatgatg tccaacaagt gacgaaaagt ctagctaaag
    43081 atgtagatgg aatctatatt cctactgata acacgttcgc aagtgcggca agtgttgtcg
    43141 gtgaagtcgc aaaagaaaca aaaacacctg tcgttgctgg cgcagttgat caagtcaaag
    43201 acggcggtct agcaacagta ggaatcgact acgaaagctt gggcaaacaa acagggatca
    43261 tggcagcaaa aatcttagac ggcaagaatc caagtgaact tcctgtcgaa acagcgaatg
    43321 atttggaact gtatgtcaat aaagacatgg ccaaagcatt aggcatcaat ccagacagca
    43381 tcaaagaagc tgaataaaac acaggaggat tctcatgaca aatttgctct ctcttttctt
    43441 atcatctgca tcgcaagggg tcttatgggc cctacttgcg attggtgtat acgtcacttt
    43501 ccgtatcttg gacattgccg acttgactgc tgaaggaagc tttcctttag gtgcagggat
    43561 cgcggcagta agtattacaa atggctatca tccattgaca gcttgtcttc taggcttttt
    43621 agggagtgcg gcagcagggc ttgtttccgg actgcttcac acaaaattga aaattcccgc
    43681 ccttcttgca gggatcatca ccatgactgg tttatattct gtcacatccc gtgtgatggg
    43741 tgcgccgaac atctctttat tgggtcagcc aacgatcttt cattgggtcg agtcattcgg
    43801 cataacaaaa gacaacgctg tactgatcgt cggtctgctt tttgctttga tcgttgtatg
    43861 tttacttgtt ttgttcttac gtacagaaac aggacttgct attcgtgcaa ctggcgataa
    43921 tctggcaatg agcgaagcaa acgggatcaa cacagataat atgaagatca tcggttatat
    43981 gatttctaat ggatgcattg ctctttctgg ctccttgctt gcgcaaaaca acggctttgc
    44041 tgatttaaat tctggtattg gaacgatcgt aattggactt gcttctatta tcatcgcaga
    44101 agttttgtta cgtaaccagc cactatttct ccgtctcttg actgtcgttt taggtgcggt
    44161 catttatcgt tttattttag cgttagtctt cgaactgaat gttgaaccaa gtgattcgaa
    44221 acttgcttct gctttcgtgc tagtgatctg tctttctttc ccgcagatcc agcaaaaatt
    44281 ccatttacct caaaaaaaga aaggcggtag tgtcaaatga atgacgtctt aacattggaa
    44341 aatctccatc atacctttga aaaaggaacg atcaacgaaa atcatgtcct gaaaggcatt
    44401 aatctttcct tagatcccgg cgacttcgtg acgatcatcg gtggaaatgg ggctggtaaa
    44461 tctactttgc tgaacagcat cgccggtaca ttttctgtcg atcagggtca aattttattg
    44521 aatggaaaaa atatcacgaa aaaatctgtt gtcgaacgtt cgaaatccat cagtcgcgta
    44581 ttccaagatc ctaaactagg gacagccgtt cgtttaacgg tagaagaaaa tcttgctctt
    44641 gctatgaaac gaggaaaaaa acgcggcttc ttccgtggtg tcaaaccaca agaccgaaca
    44701 tttttcaaag accagctggt tcggctaaat ttggggttgg aaaatcgttt atcctcagaa
    44761 atcggtttgc tgtctggagg acaacgtcaa gctattacgt tattgatggc cacattacag
    44821 cgtccagaac tgatcttatt agatgaacac actgcagcgc ttgaccctgc tacttccaaa
    44881 acggtgatgg aattgacaga aaagctgatc actgagcaga atctcactgc ttttatggtc
    44941 actcatgaca tggaagacgc gatccgctat gggagtcgac tgatcatgct gcatcaagga
    45001 aggatcgtcg tagatatcca gcaagaggaa aaacagcagc tcacagtgcc ccaattatta
    45061 gcgttgttca aacaaaacag cggcacggca ttaaaagacg atcaagtact tttatcttca
    45121 taatcagaaa gaggatggga caaaaaatga acgcccaccc tcttcttttt tctctttcct
    45181 tctttcgttt ttgctttatg tatcaaccgt tgtttcttcg aaaactattt tgttctctcc
    45241 ttcttcctga tagaatggat gggaaaggag cttgatgcca tgacaacgaa agacaaggta
    45301 cttcaattat tgaaaaagac accagatttt ctttccggag aaaagttggc acagcaactg
    45361 gaagtttccc ggacaagtat ttggaaagcc atcaaagaat tggaaaaggc aggctatcgt
    45421 tttgagcacg ggcctacagg gtatcgttac ctgccctctg acgtactaga tgcaaaagaa
    45481 atccagcaag agctacggtc gtttattcct gatttgaaag tacaaacgat gatgacttct
    45541 gaatctacga tgaaagatgc caaactggca gcagctcaag gagattctgt ttcgaagtta
    45601 tttgttgctg atacacaaga acaagctcgt ggacgttttg gacggccttt tttcgctgaa
    45661 cctggacgag gaatctacat gagtctcttg ctccatccag acaaacggtt tgatgaattg
    45721 cctcaatata cgatcatcgc agccagtgcc tgtgtgaaag ccattgaatc tgtaaccggt
    45781 cgttctgctt cgatcaaatg ggtcaatgat atctacatgg atggaaaaaa agtctgtggg
    45841 attttatctg aagcagtcag tgatatggaa agcggcagga tcagtcatat catcattggg
    45901 atcgggctta atttttctgt tcctcaaaat cattttccag ctgatctcca agaaaaagcc
    45961 atctctgtct ttcccgacgg acaagctagt gtcacaagga atcagctaat cagcaaaatc
    46021 tggcaagaat tgttcactta tctttctcac ccagaaaaag cgttggactt ctataaagaa
    46081 aaatcattcg tattgggaaa aaccgtgtcg ttcaatcaaa aaggaacgac ttatgtcggt
    46141 cttgcaaaag aaatcggtga tcatggcgaa ctgatcgtcc aaacaaatga acagaagatg
    46201 agtttgtctt ctggcgaaat cagtctcaca tctatccgta cgcaataatt atcagatttc
    46261 acaaaaggac acctgatctc atacagtgtc cttttttctg aattctcttc aaaagactct
    46321 ccttattcta tcagctgaca gtttctctat cctctagaaa aaggtattct aaaaatatct
    46381 ataaagcatg gtacactttc tttaaatgaa tcaatgcaaa aaacaagaga gtcatcagtt
    46441 tacacgatca aaagagatag caggccgctt cctttttcaa tcttatagat agaccatggg
    46501 taacgataaa aacaaaaaag aacttgcgac ttattttgcc gtaagttctt ttttagctag
    46561 tgccttaatc tcttaatccc aacaaacgtc tcgcatagat cacctgacca gagtgcatag
    46621 cagcatcatc aataatagaa acgagacgca ttcctcgtgt gactggtggt gtccagttct
    46681 cgtcaattac ttcatctagc tcggaaggtt ccagccttct taagtaagaa atagcaaaat
    46741 cagcagctcc tcgcaagtat cctagcagat cttctatttg attagcttgg atctgctttg
    46801 cttgttccag actatgcttc caatcttgtt cgttatctgc tatcgtcatc ggaaaccggc
    46861 tttcccagtc ttgactatgc caaattggag aagttcctgc taaatcagca atctggaaat
    46921 ctaattctcg agcggtatgc caagccagcc aagtcattga tttgatctgc ggggctctat
    46981 cttccactgg aaaacgattg gcctcctcaa tagagacgcc ttcaaacaaa cgttcaaacc
    47041 gatcgtatgc ccgatccaca ctctcgcata gcatatctaa ataatccatt tattttcctc
    47101 ctttttattt atcctactta ctttttccta attctaggat acctacttat atgttactac
    47161 acacccttat tttttacact ttaacagtca ccatcatcaa tagtttggag attgaaagaa
    47221 aaagatagtg tcgaactatc aattgaacaa gaagcaacaa tatgaacgtt tcattaatat
    47281 tctttaaata aacaatgatt tttcaaacga acagtttaag actaggagaa aaagagtata
    47341 ataggaaaat gtttgaaagg aaaggaaggg gaaaaatgaa aaaaagggca agtttactag
    47401 tcctagttgc tttgttgttc aatatctttt cgtatggtgt ggccgtttca gcggaaacat
    47461 acattcctaa agaccctggg aatatttata atgatctaac tggtaactat ggcttgttag
    47521 gaattgctag tcaattccac gtatttgcta aaaataagac aactgtgaat gcacatacag
    47581 acggaaatat agcaacacat gaacttgatg caaaaaataa ttttggtaca gagcttcatg
    47641 aaggtttatt gaaccaagaa ataaattata tacaaaaaac tgattctttc gctaattctt
    47701 caggcatacc tacaggtagc acaagaatga ataaatttgt cgttggcagt aacgtggatg
    47761 tagcacttca agatggtcat cctacagtca atggatccag gcttgatcac ttaactccag
    47821 atgattttta taaagatcgt gctgggcatg aatatattga tttcgagcag gaatttgcta
    47881 aattgaatgt agcagcaaat gatcttgcaa cgatcactcc agctaaaaca tatactgctg
    47941 cagattttcc agacatgaac aatcggacaa tcgatttaac tgatttatca gataccgggt
    48001 ttttattggt aaatatcgat gcagaagtgt taacgatgaa tacgccactt caaatcatta
    48061 atccaaatga tcaagtagtt gtatttaatg tcatcaacag ttcttctgca ttgaacgtac
    48121 agtcaccaat caaatacaat gatcgttcaa atcatgaaac agaagatttt tcggatgcga
    48181 atatctcttg gaattttgga aatgagatga ctgatttgac aatcagtgct ccttttcaag
    48241 gaacaatcct tgcgcctaat gctactatcc gcattactca aaaccaagac ggaacgatta
    48301 taggaacaaa tgtgatttta gatgcagcta ccaatcgttg ggatcctaac gaaatattta
    48361 tcagcgacaa tggtacagat acgacagaca caagcgacag tacagataca tctaccacaa
    48421 gtgatagctc agattcatca
//
LOCUS       DADQDV010000016        47222 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.016, whole genome shotgun sequence.
ACCESSION   DADQDV010000016 DADQDV010000000
VERSION     DADQDV010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 47222)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47222)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47222
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.016"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(27..1259)
                     /locus_tag="J8S10_000947"
     CDS             complement(27..1259)
                     /locus_tag="J8S10_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HAZ9629549.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            1514..2083
                     /locus_tag="J8S10_000948"
     CDS             1514..2083
                     /locus_tag="J8S10_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAZ9629550.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(2261..2701)
                     /locus_tag="J8S10_000949"
     CDS             complement(2261..2701)
                     /locus_tag="J8S10_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HAZ9629551.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            2859..3623
                     /gene="map"
                     /locus_tag="J8S10_000950"
     CDS             2859..3623
                     /gene="map"
                     /locus_tag="J8S10_000950"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HAZ9629552.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            3655..4578
                     /locus_tag="J8S10_000951"
     CDS             3655..4578
                     /locus_tag="J8S10_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HAZ9629553.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            complement(4803..5042)
                     /locus_tag="J8S10_000952"
     CDS             complement(4803..5042)
                     /locus_tag="J8S10_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008788617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAZ9629554.1"
                     /translation="MSKDYGYPSFELICKASSGDEMAVKEILKFYDGYISKLCLRPFY
                     HSESGKIIMQVDEELKGEIHTDMMKAILKFEIGVK"
     gene            complement(5047..5466)
                     /locus_tag="J8S10_000953"
     CDS             complement(5047..5466)
                     /locus_tag="J8S10_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009269612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAZ9629555.1"
                     /translation="MRTSSFEHIVRLQFNSLMLIVIKNKVKSRNRQLARHSKREVLFC
                     EIAETKQVERGTIDTCFYDCVSFKVLHFTIYVSDETLGTVLHRLSEKQRSAILLRYFQ
                     GMNDREISELYHVSRSAICSRRTRGLRKLKMLLSERK"
     gene            complement(5693..6931)
                     /locus_tag="J8S10_000954"
     CDS             complement(5693..6931)
                     /locus_tag="J8S10_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004081244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAZ9629556.1"
                     /translation="MQAEKKLFNRDFILVVIGQIISLFGNAILRFALPYYLLKETGSS
                     ALFGIATACSFLPMVILSLVGGIIADRTNKRNIMVILDFVTAIIILVFYLSLGKIPII
                     PLFIVALMLLYGISGAYQPAVQASIPLLVSSDKLTVGNAIINQVNTLANFIGPAISGV
                     VFQFYGINPILIVSIICFTFSAIMEIFIHIPHQKRPREVGVIAVAKNDLKDSYTFLKK
                     EKPIFISVIFLVCIFNLVLSAVLIVGLPILISEVLKMPDTLYGFSQSALSLGGLCGGI
                     LTALVASKLKLKNLYTLLLICSVSVLLMGISLFLELPAIVSYWVVTVMCFVAMGVSTM
                     FVVQIYTLVQTQTPPQLVGKIMATLVAVAMCGQPIGQMVYGILFDVFIQETWVVMFVA
                     SIASIMISIYSKRIFQKLEI"
     gene            complement(7038..7673)
                     /locus_tag="J8S10_000955"
     CDS             complement(7038..7673)
                     /locus_tag="J8S10_000955"
                     /inference="COORDINATES: protein motif:HMM:NF012655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAZ9629557.1"
                     /translation="MARNKYPEETVKLILDVSTKMFCEKGYDNTSLQDIINETKLSKG
                     AIYHHFDSKEDILKAIFQRIGNENAVIFAKIRDNDSLNGLEKLREIFKTAVFNSNQSV
                     LLTVSPQLLNNPRFLAMQIEQMYEIVVPEFVEPVLEQGIKDKSLEIENSHEIAEVIMV
                     LSNVWLNPLVEMTDKEGMEKRCNTFNALLNGIGIDTLLDEETISAFIQFCK"
     gene            complement(7787..7879)
                     /locus_tag="J8S10_000956"
                     /pseudo
     CDS             complement(7787..7879)
                     /locus_tag="J8S10_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323349.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            complement(8015..8650)
                     /locus_tag="J8S10_000957"
     CDS             complement(8015..8650)
                     /locus_tag="J8S10_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAZ9629558.1"
                     /translation="MEGYAMKISHLGNNIQTIRKFRGMKQQELADKIGINMQSLSKIE
                     RGLNYPAYETLEKIMEVLDVTPNELLSGEWKYVNQSEKEVCQFLRAEERLNAELKHGH
                     YDNFFDSEEEWLEYELEKLREYITDYINGKSIEASDLYPIKEFIQHLKFQKLLDRYDD
                     LYSMDMFGESIEGHKYKTPYQVVKMINPNSKEDMELLREVLRNNNFDDEDE"
     gene            9162..10304
                     /locus_tag="J8S10_000958"
     CDS             9162..10304
                     /locus_tag="J8S10_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAZ9629559.1"
                     /translation="MNNLEFALEMKNKRLASGLSQGELASLTHVSRYSINRFENGKAN
                     ASKETQNIILRCLNYYICDKPFYLLVDYLSVRFPTTDALEVIRKVLGMKADYFIHYDY
                     GYYGYKEHYAYGEIKVMASDDEHMGVFLELKGAGSRNMEYVLQAQNRDWYSFLNRCLD
                     CGGVIRRFDLAINDMCGLLDIPVLSEKYRNGGAECRCKNYENVQGGKLSGKNRNLAST
                     LYIGSKASTKYFCLYEKQKEQATKKKHTDIINRFEIRLRDKKAVQAVEELLLTYNPHG
                     LVFYLITDFVEFPDYPLWEIFISHDSLPFEMNPVPVNMERTLQWLERQVMPSIVMIEE
                     IDRLTGSNYMKMIDECTHLSEKQEMLVEQMCTDISDVIESEGVFYE"
     gene            10297..10503
                     /locus_tag="J8S10_000959"
     CDS             10297..10503
                     /locus_tag="J8S10_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HAZ9629560.1"
                     /translation="MSNTQDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWL
                     IMNGNRIQIKRRQFEKVIDKLDAI"
     gene            10582..11775
                     /locus_tag="J8S10_000960"
     CDS             10582..11775
                     /locus_tag="J8S10_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAZ9629561.1"
                     /translation="MKEKRRDNKGRILHTGESQRTDGKYLYKYVDALGNTKYVYAWRL
                     TPTDPTPKGKREKPSLRELEQQIRRDIEDGIDSTGKKMTLCQLYAKQNAQRTNVKKST
                     QKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKDKGFSYNTINNHKRSLKASFY
                     IAIQDDYVRKNPFDFKLSEVIENDTKEKVALTEEQEQALLSFIKTDNVYHKHYDDVLI
                     LLKTGLRISELCGLTVADIDFKNEVVIIDHQLLKSKEQGYYIETPKTKSGIRQVPLSK
                     ETIQAFQRVINSRPKIKSIEVDGHSGFVFINPKGNPKVAIDYNALFIRMVKKYNKHHK
                     DNPLPHITPHTLRHTFCTRLASKNMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEV
                     QRLIA"
     gene            complement(11782..11940)
                     /locus_tag="J8S10_000961"
                     /pseudo
     CDS             complement(11782..11940)
                     /locus_tag="J8S10_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008788611.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-binding domain-containing protein"
     gene            11980..13119
                     /locus_tag="J8S10_000962"
     CDS             11980..13119
                     /locus_tag="J8S10_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HAZ9629562.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            13112..13912
                     /locus_tag="J8S10_000963"
     CDS             13112..13912
                     /locus_tag="J8S10_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAZ9629563.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            13912..14739
                     /locus_tag="J8S10_000964"
     CDS             13912..14739
                     /locus_tag="J8S10_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAZ9629564.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            14717..15451
                     /locus_tag="J8S10_000965"
     CDS             14717..15451
                     /locus_tag="J8S10_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAZ9629565.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            15551..16417
                     /gene="rfbA"
                     /locus_tag="J8S10_000966"
     CDS             15551..16417
                     /gene="rfbA"
                     /locus_tag="J8S10_000966"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HAZ9629566.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            16431..17003
                     /gene="rfbC"
                     /locus_tag="J8S10_000967"
     CDS             16431..17003
                     /gene="rfbC"
                     /locus_tag="J8S10_000967"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HAZ9629567.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            17025..18053
                     /gene="rfbB"
                     /locus_tag="J8S10_000968"
     CDS             17025..18053
                     /gene="rfbB"
                     /locus_tag="J8S10_000968"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HAZ9629568.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            18151..19002
                     /gene="rfbD"
                     /locus_tag="J8S10_000969"
     CDS             18151..19002
                     /gene="rfbD"
                     /locus_tag="J8S10_000969"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HAZ9629569.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            19036..21069
                     /locus_tag="J8S10_000970"
     CDS             19036..21069
                     /locus_tag="J8S10_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629570.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            21113..22393
                     /locus_tag="J8S10_000971"
     CDS             21113..22393
                     /locus_tag="J8S10_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HAZ9629571.1"
                     /translation="MEIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGLGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFSVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNIIGSSLMTLALLISGFASSFERWYVRIIGAVAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQILLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVAEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            22603..23409
                     /locus_tag="J8S10_000972"
     CDS             22603..23409
                     /locus_tag="J8S10_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9629572.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            23421..24641
                     /locus_tag="J8S10_000973"
     CDS             23421..24641
                     /locus_tag="J8S10_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9629573.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            24631..26217
                     /locus_tag="J8S10_000974"
     CDS             24631..26217
                     /locus_tag="J8S10_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAZ9629574.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            26256..28394
                     /locus_tag="J8S10_000975"
     CDS             26256..28394
                     /locus_tag="J8S10_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAZ9629575.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(28762..29745)
                     /locus_tag="J8S10_000976"
     CDS             complement(28762..29745)
                     /locus_tag="J8S10_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HAZ9629576.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
     gene            30123..31514
                     /locus_tag="J8S10_000977"
     CDS             30123..31514
                     /locus_tag="J8S10_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HAZ9629577.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSSQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            31530..32570
                     /locus_tag="J8S10_000978"
     CDS             31530..32570
                     /locus_tag="J8S10_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAZ9629578.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRTIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDEAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            32589..33674
                     /locus_tag="J8S10_000979"
     CDS             32589..33674
                     /locus_tag="J8S10_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HAZ9629579.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGRIFVVPNPKKNIFKYLIEVNKLLKKESFSIVHNQVYFGGGINLWL
                     AKKNGIRQRIAHSHATEDGKSQNIVMNVLRKFLTKLLLQNATDYLAVSQEAGESLFQN
                     HPFEIVHNGIDLELYSKNSEAKVNKRKELDISMSTFVVGNIGRLEKQKNQSYLLEIFL
                     EILKMNSDSYLILVGEGSLRNKLKAKAVELDIEKRVKFLGERNDIPELLSVMDVFVMP
                     SLYEGLPMVGLEAQAAKLKLVLADTISKDTKLTNNVDFVSLDETPQEWAKKVIKEPYA
                     NKITQELKSYDVSYTTEQMESIYSRDH"
     gene            33707..34669
                     /locus_tag="J8S10_000980"
     CDS             33707..34669
                     /locus_tag="J8S10_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-1,6-N-acetylglucosaminyltransferase"
                     /protein_id="HAZ9629580.1"
                     /translation="MKICYLILAYNDIGNLKRLVNRLNENAVFIIHIDKKTDIEPFIE
                     AFKSYDNVEFLCNKNRVKIYWGGFSIVQAEINLVKRALQNEKYLKYVLLSGADYPIKD
                     NEYIYNYFKKNSSVEFIRGIDLDQIKHKEFYYKHIDVYQKHDYPRINRNNTTAFKIFR
                     AIINRCLRMIKLPPKIRHHKFDLYHGSQWWALSKECLTELIQMYEQNQQDYLNFKIGM
                     FAPDEKFFHTLFFNSSFKNKNVIGGPDLPLELKNIEETTLQTSKLANIHIIDPSMNKW
                     FDERDIDQIKESEKLFVRKVKSDYSDKLLNRIDKEILKVGNIDE"
     gene            34662..36089
                     /locus_tag="J8S10_000981"
     CDS             34662..36089
                     /locus_tag="J8S10_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HAZ9629581.1"
                     /translation="MNRIVPVLEKSLLSRDAFRVINLIICLLYFMPSTFNVTNIPMKI
                     AFAWGGIIVLYEVFIKKNFFKMRFSWLLIGAMISFILTIIINRENFLIPSIYNFGYLL
                     ITLIVIFPADFSQSEEEKKKKMVYFNNVFIIIIFLAALISIYQFIFLISYHVPTGTPG
                     LLARQGFIEHRLFGVYTSPNVGAMFGYTSIILSLISVLISKITKTIRVFYMMNFIVQI
                     FYITLSSSRGAQVVICSFLVLFLLLFANSKFRKSIREVLPVKIKWMVSILLVLLVYFS
                     FGTNYAKDFLATIPVSIDRKVEVIESNESDKTPLPEKEVILQHSSDNSEISAGRFTIW
                     KAALKVIRPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNELKRAHGNMHNGFLQVLV
                     SSGIIAFICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIFILSIFIDEMVEAHVLFN
                     KRDVISIVFWYYLGSISYLYLKKEN"
     gene            36091..37161
                     /locus_tag="J8S10_000982"
     CDS             36091..37161
                     /locus_tag="J8S10_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629582.1"
                     /translation="MKTAFIAWTPLHLINILNVYQNFYRESKGDLFIYSEFENARRYS
                     ERIKELGLFNDVVFVNHRKIGSSFKRKINLLTNHNQFFSDDLSVYDEIFIQGENYFTK
                     ILFSNVYKKNPDVKLNYIEDGLGTYLKKSIFSTSKNVQRVFKILNKNSIFKKKIDDYF
                     VYCPELLLYDVKNIKKIPKIDENSKLMKNIQSIFGIEEVFVGDKCIFFDQPLLSDGYG
                     IDETDIFAKVNSIFSGKKETLIKLHPRARTNRYGEKNILNSSLPFEVLLLENDFSSTL
                     LISPISTISFSPSMMFEKTINSIMLAKLILNEYTALSEDKKETLTNIVLFCEHYNRLS
                     EEKILLPENWAELRKLVEYGII"
     gene            37148..38569
                     /locus_tag="J8S10_000983"
     CDS             37148..38569
                     /locus_tag="J8S10_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HAZ9629583.1"
                     /translation="MGLFNTLSKSKLVKSSFWYTIGNFFIKGISFITIPIFVNITTQA
                     EYGLINNFTSFVSIFSILVGLSLNSAINNASFDYKDDINEFMSSVLSLATLSLIVFLL
                     IGNIYFLFSNAFFDMNQLVFNLMLLQSFASFVISYIQSYFTINFNHFKYLILSFISTF
                     LNIAISVALMQTLYFDDKYVGRVVGGTLSFVLIGLVIYLRIMIKGAHFFDKKQWRYAL
                     KISLPLIPHSLANIVLAQFDRIMINSYLGPAAGGIYSYISNIGIILSVIWMSTNNAWV
                     PWFYGEMSKNNEKKVKKVSNYYLVVFTLITMIVMVVSIDLAKFMAPKDYYSGLSLVVP
                     ITLGYFFQFLYSLPVNAEFYEKKTSFIAIGTVASAIVNILLNMIFIPRLGIIAAGYTT
                     VFTYFLLFIFHYNIAKKITNKQLFDTKKICIIIIFVSIFSLILHILINQMLIRYVLTS
                     LLIISLVIYFLKIKNRIIDDYNS"
     gene            38582..39589
                     /locus_tag="J8S10_000984"
     CDS             38582..39589
                     /locus_tag="J8S10_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAZ9629584.1"
                     /translation="MFKGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFY
                     MQQELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNV
                     MGTQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIF
                     SCVRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSK
                     FGETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEI
                     ERSYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVT
                     W"
     gene            39601..40605
                     /gene="neuB"
                     /locus_tag="J8S10_000985"
     CDS             39601..40605
                     /gene="neuB"
                     /locus_tag="J8S10_000985"
                     /EC_number="2.5.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HAZ9629585.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQKDNLKEDSSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFD
                     EESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFI
                     DSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVGYSDHSLGYDVGICAVAMGAKV
                     IEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEIFLGDGVKRAMPSELSTKEVSR
                     KSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQYIGKKVKRPISADSVLLEEDVE
                     "
     gene            40602..41750
                     /gene="neuC"
                     /locus_tag="J8S10_000986"
     CDS             40602..41750
                     /gene="neuC"
                     /locus_tag="J8S10_000986"
                     /EC_number="3.2.1.183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (hydrolyzing)"
                     /protein_id="HAZ9629586.1"
                     /translation="MKKILIVSGTRADYGIYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGAPRIDTILNNRLPSFRDIKEKYHLKFEKKKYVLQVFHPVVTELENI
                     EKQILALINSMEQQSQPIICILPNSDAGSEIIRKMYQKYLKTDIIYITNLEPEEYLTI
                     LKECKFMIGNSSSGIIEAASFKIPVINLGTRQNGREQSKNIINANLNENEIETALNKI
                     QDPQFIKSLKNVKNIYGDGNSSRRITKTLNQILNDGEDIKWIQKQIAY"
     gene            41723..42400
                     /locus_tag="J8S10_000987"
     CDS             41723..42400
                     /locus_tag="J8S10_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HAZ9629587.1"
                     /translation="MDSKTNSLLKYTSDPYIIIGAGGHAKVIIETLRLENKLIYGFFD
                     DKQNKMQDLKYLGKINELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIA
                     VHPSAIVAKEISIGYGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPG
                     VCLAGGVHVGVGTQIGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKK
                     EGINFEF"
     gene            42390..43532
                     /locus_tag="J8S10_000988"
     CDS             42390..43532
                     /locus_tag="J8S10_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HAZ9629588.1"
                     /translation="MNSRILLSSPHMGGTEEKYVAKAFKDNWIAPLGENVDKFEESIT
                     KYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATVNPILYQGAVPVFI
                     DSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYERILAIANQFNVPVI
                     EDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSDKKYVEHSRFLATQ
                     ARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIFNRYKEAFSGIDRI
                     EMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRALWKPLHLQPVFQG
                     VKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIFK"
     gene            43545..44522
                     /locus_tag="J8S10_000989"
     CDS             43545..44522
                     /locus_tag="J8S10_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAZ9629589.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVFVCTSPITHEFIIKEALNLDCNIFTEINLLNEYYDEI
                     IEVAKKKDRLLYLSSTFLKRKEIQYIKSKVTHNKKISYQYHVGQYLPDWHPWEDYRNF
                     FVSNKKTNGCREIFAIELPWIIDTFGKVKSFTVMTQKLSNLDIDYSDSFTLIIEHETG
                     IVGTLSVDVVSRVAKRNLTIIGEKILIEWEGNPDSLFSWNEETSSMTDIQLYDEVMHD
                     NNYSHTIIEDAYLEEIKEFFTLLEKKMEPQYTFEKDKYIINLINDIEVN"
     gene            44522..45430
                     /locus_tag="J8S10_000990"
     CDS             44522..45430
                     /locus_tag="J8S10_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HAZ9629590.1"
                     /translation="MMKVIFFGLGSIGKRHLKNLISYGKKNSINFDITAYSSSGKKEF
                     EEITYIQNRDDLDTHYDIAFITNPTFKHLETLNVIVEKVDYIFLEKPAFSESIDLTQY
                     NYDYKNIYVAAPLRYKNIMEVVRNSIQSKKVYSVRAICSTYLPDWRKGTDYRNNYSAF
                     KSMGGGVELDCIHELDYIINLFGFPKSVKKQFGKYSNLEINSNDLATYILRYDDKIIE
                     IHLDYFGRVPTRKFQLFTLDECINVDLLNNKISFEENIVKEMPESANDMYEKELKYFF
                     ENVVTGKENWNDLYHANEVLKIAEEK"
     gene            45431..46183
                     /locus_tag="J8S10_000991"
     CDS             45431..46183
                     /locus_tag="J8S10_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HAZ9629591.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFLQLERED
                     NIFDLIIDLDLTSPLREVSNLEELIDEHLKNLDKDVYFSVVSARRNPYFNMVKRIENE
                     VTIVNKSRYTSRQQTPEVFEMNASMYSFKPEFLKKSNYIFDGQCGIIKMRDYLILDID
                     SEEDFKWLEFLFPKFLEDSSELQDIYNYLYRR"
     gene            46188..47135
                     /locus_tag="J8S10_000992"
     CDS             46188..47135
                     /locus_tag="J8S10_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HAZ9629592.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
BASE COUNT        15783 a         7469 c         9074 g        14896 t
ORIGIN      
        1 ttttttgcat gtgtgcgaaa gtatactcaa gcccaatcgc catttcggaa aatcggtact
       61 gtagagccat cttcacggat tccgtcgata tccatcttgt cagatcctac catgaaatct
      121 acgtgggttt gacttctatt caatccagct tctgctaatt cttcatcgga catttctgta
      181 ccgcctttca cactgaaggc ataagcagaa cctagtgcta agtgattcga tgcgttttca
      241 tcaaataatg tattgaaaaa gatgatgcca gattgagaaa taggtgaagg gtcaggtaca
      301 agtgcgactt ctcctaaacg acgcgcacct tcatctgtat caagcagttt tgctaagaca
      361 tcttctcctt gttcggcaga aaaatcaaca acttttccat ctttaaaagt aaatttcata
      421 cccgagatga tggtgccagc ataactcagt ggctttgtac ttgaaatgta accatctact
      481 cgatgactgt caggtgctgt gaacacttct tccgtcggca tatttgccat gaatttttct
      541 ccacgagcat tatagcttcc agcgccttcc caaagatggt ttttaggcaa tccgataatg
      601 atatctgtac cgggagcagt atagtgaagg gcagaaaatt gttctcgatt caattcttct
      661 gctttttttg ctaatttttc atcatgcttc ttccatgcta agacagggtc ttcttcatag
      721 acacgagtcg ttttgaaaat ctgatcccat aatgcctcaa cttgtttttc ttctggcagt
      781 tctgggaaga cttttgctgc ccattgttta ccagccgcag ccacgacagt ccaactgact
      841 ttatttgctt gagttgcctt gcgtaaattc attagtgctt tgccattcgc tgattgataa
      901 gacgctactc gatggctatc tacaccagca aatgcatcgg gatcggcaga aacaacgctg
      961 atcctgcttg ctcctttttc aagccattca tccgcttgat cgattttaga ttgtggtaca
     1021 ttctcaatac gatccgttgc agcatgtaaa agaaattctc tttggatctg gtcgtcagtc
     1081 cattgaacga taacctcagc ggctcctagt ttataagctt cttgtgtgat caatcgagca
     1141 aggggtgcct gttccacgct gatctgtaaa acaactgtgt gtcctttttc tgtggctacg
     1201 ccagtttctg caattaagcg tgcatatttt tttagaagtt cattaaaatc agataacata
     1261 ataaaaattc ctcctcacca ttttttctgg taactattag catgatacca tttaattatg
     1321 attcaaacaa tgaggcttta aataaaaaaa ggaggttatt tttttaaggt taagtttcat
     1381 gatatatgtt actacttgct atttcagctt gtgaagaaaa tcaaaaacta attttgcata
     1441 tcaaaaaaaa catgttacaa tgaaattaat caatggtgga agcgttataa aaaaattaag
     1501 gagattaaaa aatatggcaa gaaaaaagac gattactaga gaacagattt tggcagctgc
     1561 ttatgaagta gctgccaccg atggatttac acgatttact gcgagaaaca tcgcgaacaa
     1621 aatgaattgt tccacgcaac cgatttatct tgagtttaaa aatatggatg acttgagaca
     1681 agctcttttt gagcagatct atgatcattt acaatatgaa gtgttcactg ttgagcatac
     1741 agggaatacg attatcgatc ttgcttttaa ttatatccat tttgcaagaa gagagaagaa
     1801 gttgtatcgt tcactgtact tagaagaata tggtggagga aaagagatgc agaatttctc
     1861 ttatacttac tttgtgaata cagtgaaacg cgatccagct tatgtgaatc tttcagaaga
     1921 gcagatcgaa tctttgtata atgggacatg gatcatagct actgggatcg cagctttgat
     1981 gtcttcaagc atcatccatc caactgatga acagattgaa aagatgatcc aagacagtat
     2041 agatgctatc ttgaaattca aagaaccaat cgaaatcgat tgaatatact caaaagttcc
     2101 acaaatcagt aggtaacaag agatgtgtca aaataaggaa aagttcgttt ttcttacagc
     2161 gtatgcattt ttaactcccg aagaactctt ccatgaatgc aatgaataaa agagccatac
     2221 agattgaata aatctggatg gctcttttat tgcaagtata ttaaattttt gcgactagtt
     2281 ctttagcgaa agcttctaaa ttttcgatat cttcttcttc agcattcaga tccactttaa
     2341 cattttcggc tccttttgat gcgcctgttt ttgcaaaagc agcatcgaaa tcatccaccg
     2401 atttgcagaa ttcatcgtaa aaagtatcac cagatccgca gacaccgtaa atttttccca
     2461 atagatccaa ttcttgcaag tcttcataaa agtctacgat ctcatcaggc agatcgccat
     2521 catcgtatgt ataagtagct actacgcaaa tatctgcctc ctcgaattca tctgcatcta
     2581 cttgggtaca ttcgttgatt tcgacttcga tatccagatt ttcaaatgct tctgcaacaa
     2641 tatcggcgat ttcttcagtg tttcctgtca tgctagcata tacgattttt gctaaagcca
     2701 tgatgtgcct cctcgtttat aattatttaa caattatgaa ttataccaaa acatcattga
     2761 aaagaaaata aaacctagag acacctgggg aatgtcattt ggctaaatgt atgccgctat
     2821 gttaaaatga gagggatttg taaaaaggag acgaaaatat gattacttta aaatcagcac
     2881 gtgaaattga aatgatggca gaatctggag ctttattagc agatgtacat aaaaatctgc
     2941 gtgattttat aaaaccagga atcacaagtt gggatattga ggtatttgtc agaaactata
     3001 tcgagagtca tggcggaatt gctgcgcaaa ttggctttga agggtatgaa tatgcgactt
     3061 gtatcagtat aaatgatgaa atttgtcatg gattccctcg taaaaagcct ttgaaaaacg
     3121 gtgatttggt aaaagtcgat atgtgtatcg atttgaaagg cggcatttct gattcttgtt
     3181 gggcctatgt agttggagaa tctacacctg agatcgaccg attgatggaa gtaacgaaga
     3241 aagctttgta catcggtatt gagcaagcac aagtagggaa tcggattggt gacatcggtc
     3301 atgctatcca aacttatgta gaaggcgaaa atctagcgat cgttcgtgat tttattggtc
     3361 atggcgttgg tcctacgatt catgaagaac cagcagttcc tcattacgga gaagctggaa
     3421 aagggttgcg gttgaaagaa ggcatggtta tcacgatcga acctatggtt aataccggaa
     3481 cttggaaaat gaaaatggat cctaacggct ggactgcgta tacaagagac ggcggacttt
     3541 cttgccaata tgaacataca ttggctatta ctaaagatgg tccaagaatt ttgacatcac
     3601 aaggagaaga aggcacttat tgatctatcc agtcaatagg tacgggagag gtacatgaaa
     3661 gtttggaaca aaataaaaca aaatgaaaat ctgatgcgct ttattgagac gactcaaaag
     3721 cgcatcactg attcagaaat gagtacgacc tctgtcgtcg ttgcttatta tttactcttg
     3781 tctttatttc cattgattat tgcttttggt aatattttac cgtttctcca catcgatcaa
     3841 gagactgtac tgacctattt acgagaagtg attcctgaga ccgtttacca gtttatcggt
     3901 cctgcaatca aagacctttt gacacaaagt tcaggaggct tgttatccgt ttctgcatta
     3961 gcggctttat ggtctgcaag tcaaagtatc aatgctttgc aaattgcgat gaataaagcg
     4021 tatggcgtag aaaatagaaa aaattttttg atcgtccgtt tcttctcact aattgtcatt
     4081 gtcttgttca tgattgctat tagtggggta actatcgttc ttgggttggg acagctgatt
     4141 ttggatgcta ttcagccaat cgtacaaata cccgtgaact ttatcgatca gttccaaact
     4201 ttgaagtggc caatcacatt ggtagcttta tttgtcatca tgttcttgat ttatttaatt
     4261 gtccctaatg ctcagttgaa gttgaagacg atcattccgg gcacgatctt cgctactgtc
     4321 ggctggatgc tgttatcaca agtgtttagt atctatgcta ggtattttgc aacgaggatc
     4381 agcggttatc agatcatagg aagttttatt gtactcatgc tttggcttaa ttttgctgct
     4441 acgatcatca ttttgggcgg aatcatcaat gcagttgttc aagaatacgt gacgggtcat
     4501 caaatcaaaa aacgtcgaga tccaagccga aaatggttca ataaattgaa aactaaattt
     4561 tctcataaaa aaaagtagaa acaagagttc ttattgtaaa tttatatcag taatttattt
     4621 gaaattttat atctaatttt caattatccg cataaacact atacattcaa gcattttgaa
     4681 gtatagaaaa acactcatct taccacgaat ttaccacgat tgaatgagcc ttgatatgac
     4741 cgtaaaacta ctaagggaga tagcacgaaa ctgtgtatct cccgattttt ttatacagtt
     4801 gattacttca ctccgatttc aaatttcaat attgctttca tcatgtctgt atgaatttct
     4861 ccttttagtt cttcatcaac ctgcataatg attttaccac tttcagagtg gtaaaaagga
     4921 cgcaagcata atttagaaat ataaccgtca taaaacttca aaatctcttt aactgccatt
     4981 tcatctccgc ttgacgcttt gcaaatcaat tcaaaagagg gatagccata atctttactc
     5041 atttctttac ttcctttcgc tcaaaagcat ttttaacttc cttagtcctc tagttcttct
     5101 actgcaaata gcagaacgtg atacatggta cagttctgaa atttctctgt cgttcattcc
     5161 ttgaaaataa cgtaataaaa tcgcactacg ctgtttttct gacagtctat gtaaaactgt
     5221 accaagtgtt tcatcagata cataaattgt aaagtgcaag actttaaatg atacacaatc
     5281 ataaaaacag gtatcaatcg ttccacgttc aacttgtttc gtttcggcta tttcacaaaa
     5341 caatacttca cgtttagaat gtcttgcaag ctgtctgttt cgacttttca ctttgttctt
     5401 aatgacaatc agcattaaag aattgaactg taatctgacg atatgctcga aagaagatgt
     5461 cctcataatc tcaccccctt tctgctaatg ctgaaatata taaacggaat accgtttata
     5521 ccctttagaa atacagaaaa atggtaagaa aaaagcccac acaaaacata tatttgtgcg
     5581 agccttaaat actgcaatat tactctttct tttataacac tatcctttta gcagatttca
     5641 aattttcttt tatatattgt ttttagccta acatactatt taaccccttg tattatatct
     5701 ctaacttttg aaaaattctt tttgaatata ttgaaatcat gattgaagca atagaagcta
     5761 caaacataac aacccatgtt tcttgtataa atacatcgaa taaaataccg taaaccattt
     5821 gtccaatagg ttgaccgcac atagcaactg ctaccagcgt agccattatc tttcctacta
     5881 attgcggtgg tgtttgtgtc tgaacaagag tgtaaatttg aacaacaaac atagtagata
     5941 cacccatagc cacaaagcac atcactgtaa ctacccagta ggaaactatt gcaggcaatt
     6001 ctaaaaatag cgaaattccc ataagtaaaa cagaaacaga acaaataagt aacaaggtat
     6061 aaaggttttt tagttttaac tttgaagcaa caagagctgt taaaatacca ccacataaac
     6121 cacctaatga taatgctgat tgtgaaaaac catatagtgt atctggcatt tttaaaactt
     6181 cagaaattaa gataggcaga ccaacaatta aaacagcact taaaaccaaa ttgaaaatgc
     6241 aaaccaaaaa gattacggat ataaaaatgg gtttctcctt tttcaaaaag gtataactat
     6301 cttttaaatc gtttttagca actgcaatta cacctacttc acgaggtctt ttttggtgtg
     6361 gaatatggat aaaaatttcc ataatggctg aaaaagtaaa acatataata ctaacaatta
     6421 aaatgggatt gataccataa aattgaaaaa ctactccgct tatagctggt ccgataaagt
     6481 ttgctaaagt atttacttga tttattatag cattaccgac ggtaagttta tctgatgata
     6541 ccaatagagg aatacttgct tgtaccgctg gttgatatgc accagaaata ccataaagta
     6601 acatcaaagc aacaataaac aaaggtatga taggaatttt tcccaatgac aaataaaata
     6661 ctaaaattat gattgctgtt acaaaatcta gtatgaccat aatgtttctt ttatttgtcc
     6721 tgtcagcaat aataccacct accagcgaca aaataaccat aggtaaaaaa gagcaggctg
     6781 tagcaatacc aaacaaagct gatgaaccag tttcttttaa caaatagtac ggtaatgcaa
     6841 atcgtaggat agcgtttcca aataaagaaa ttatctgtcc tataacaaca agtataaaat
     6901 cacgattaaa aagttttttt tctgcttgca taaaatctct cctttttatt taatcaaaca
     6961 gaccgtcggt ttatataatg gtttaaataa actgctcttt tatagagcag tctatcgtat
     7021 agggataaca aatacagtta tttacaaaac tgtataaatg cagaaattgt ttcttcgtct
     7081 aataatgtgt ctatgcctat tccatttaaa agggcattga atgtattgca acgtttttcc
     7141 ataccctctt tatccgtcat ttcaactaat gggttgagcc atacattact taataccatg
     7201 ataacttctg caatttcatg tgaattttca atctccaaag acttatcctt gataccttgt
     7261 tctaaaacgg gttcaacaaa ttcaggtact acaatttcat acatttgttc tatttgcata
     7321 gcaagaaaac gaggattgtt taatagttga ggagaaactg tcaataaaac gctttggtta
     7381 gaattgaata ccgctgtctt aaatatttct cttaactttt ctaaaccgtt taaactatcg
     7441 ttatctctaa ttttagcaaa tattactgca ttttcatttc caattctttg aaaaattgct
     7501 tttaaaatat cttcctttga atcgaaatga tgataaatag cacctttaga aagttttgtt
     7561 tcattgataa tatcttgcaa tgatgtgtta tcatatcctt tttcacaaaa catttttgta
     7621 gaaacatcta aaatgagttt tactgtttct tctggatatt tatttcgtgc cataacttac
     7681 ctccaataca aaccgttggt ctgattaaag tatatcttag tattttatgc ttgtcaatat
     7741 aaagacttgc aattttataa aaatgcagaa tgcaagcctt tttcatttat tctacaatct
     7801 tccagttgct ttccttatgc ggtgtcaatt catactgtga tacctgcgtt gcctttgcct
     7861 gatttaccac aaatcagatt ttatcccttt cttcctcttg attgcccaca acagaaaaga
     7921 aaaagccctg tcaagagctt tgccaccatt ggtggtgctt tgcactcttg atcgggcttt
     7981 ttgtttgctg tatcttctcg caagaggaaa aaagttactc gtcctcatca tcaaaattgt
     8041 tattccttaa tacttctcgt aacagttcca tatcttcttt tgagttcggg tttatcattt
     8101 tcacgacttg ataaggtgtc ttatacttat gtccctctat gctttcccca aacatatcca
     8161 tactgtataa atcatcatag cggtctaata atttttgaaa cttcaaatgc tggataaatt
     8221 ctttgattgg gtaaaggtcg gacgcttcaa tgcttttccc gttgatatag tctgtaatat
     8281 attcccgtaa cttttctaac tcatattcca gccattcttc ctcgctgtca aagaagttat
     8341 catagtgtcc atgtttcagt tctgcattta gacgttcttc ggctcttaaa aactgacaga
     8401 cttccttttc agattgattg acatacttcc attctcccga caacaattca ttgggcgtaa
     8461 cgtccagcac ttccattatc ttttccagcg tttcataggc aggatagttc aaccctcttt
     8521 caatcttgga aaggctctgc atattgatac cgattttgtc cgcaagttcc tgttgtttca
     8581 ttcccctaaa ttttcttatg gtctgtatat tatttcctaa atggcttatt ttcattgcat
     8641 aaccctccat atctcgttat atcttcgcta ttataagtct atcatgctta atatgatttg
     8701 taaaggcaaa aaaagatatt gacaaataag catataagaa ttactatgtt cttgtaatcg
     8761 aataagcaca atagaatgaa atataaaaac attcaaaaag aaatacctat ctgattaaat
     8821 ccgtagatat gaatatcggt tgaaatggaa cttgttagaa aaggcaaaac agaacttgct
     8881 gacaaagtat ttctgacacg gtggcggaag cctctcaggc ttaccgccat gacaccttgt
     8941 gtcaagggga agaaatgctt tgtcggctgg cgagcctgcg agccttgtct gtgcccccgt
     9001 tatctaacag gggggcacta tttcacaaaa gacaagtcaa aaaccataca cccccaaacc
     9061 tgtgagtagt aatgagaggt tttaagaaga tagtacatat cacacttttt gaaaggtggt
     9121 ttacaggtat ttcaaggcta ttgtgggatt ggaggaatac aatgaacaat ttagaatttg
     9181 cacttgaaat gaagaacaaa cgtcttgcca gcggtctttc acaaggagaa cttgcaagtc
     9241 ttacccatgt atcaagatat agtatcaacc gctttgagaa cggaaaagct aacgccagca
     9301 aggaaacaca gaacattatc ctgcgttgtc tgaattacta tatctgcgat aagccttttt
     9361 atctgctcgt tgattatctg tctgtccgtt ttccaacgac tgacgcattg gaagttatcc
     9421 gaaaggtgct tggcatgaaa gcagattatt ttatccatta tgactatggg tattatggct
     9481 ataaggagca ttatgcttac ggggaaatca aggtcatggc ttctgatgat gaacacatgg
     9541 gcgtattttt agaattaaaa ggggcaggct cacgcaacat ggaatatgtc ttacaggcac
     9601 agaacaggga ctggtattca ttcttaaacc gctgtcttga ctgtggcggt gttatccgac
     9661 gttttgactt ggcaatcaat gatatgtgcg gtctgctgga tattcctgtg ctatctgaaa
     9721 aatacagaaa tggtggtgcg gaatgtcgct gtaaaaacta tgaaaatgta caaggtggaa
     9781 aattaagcgg aaaaaaccgt aatttagcaa gtacccttta tatcggctca aaggcaagca
     9841 caaaatattt ctgcctgtat gaaaaacaaa aggaacaggc aacgaaaaag aaacataccg
     9901 atattatcaa ccgttttgaa attcgtctgc gtgacaaaaa ggcggtacag gcagttgaag
     9961 aactgttatt gacgtataac cctcatgggc tggtgtttta tctcattacc gattttgtgg
    10021 aatttcctga ctatccattg tgggagatat tcatttccca tgacagttta ccttttgaaa
    10081 tgaaccctgt acctgtcaat atggaacgca ctctgcaatg gctggaaaga caggtcatgc
    10141 cgtcaatcgt gatgatagag gaaatcgaca ggctgacagg ttcaaactac atgaaaatga
    10201 ttgatgaatg tacccacctt tctgaaaaac aggaaatgct tgtggaacag atgtgtacgg
    10261 acatatcaga cgtaatcgaa agtgaggggg tgttttatga gtaatacaca ggatattccc
    10321 gtatgggaaa aatacaccct taccattgaa gaagcgtcaa agtatttccg cattggagaa
    10381 aacaagttaa gacgattggc agaggaaaac aaggacgctg gctggctcat tatgaatggc
    10441 aaccgcatac agattaaacg ccgacagttt gaaaaggtta ttgataaatt ggacgcaatc
    10501 taatgcaaat gagccttgta tgtgttatga tgaacacaag tcatatcaag gctctttcca
    10561 acaaggaaag gagcagacac catgaaagaa aaaagacggg ataacaaagg tcgtatcctg
    10621 catactggag agagccaacg aacagacgga aaatacttat ataaatatgt agacgcattg
    10681 ggaaacacaa aatatgtgta tgcttggaga ttgacaccca cagacccgac accaaaggga
    10741 aaacgggaaa aaccctcact tcgagaactg gaacagcaga taagacggga tattgaggac
    10801 ggtatcgaca gcacaggcaa gaaaatgacg ctttgccaac tctatgccaa acagaacgca
    10861 cagaggacaa atgtgaagaa aagcacacag aaacaacggg aacaactcat gcggttatta
    10921 aaagaggaca agttaggtgc taggagcatt gatacgataa aaccctctga cgctaaagaa
    10981 tgggcgttac gcatgaaaga caaaggcttt tcctacaata ccattaacaa ccataaacgc
    11041 tcgttaaaag cgtcattcta catagccata caagatgatt atgtgaggaa aaaccctttt
    11101 gatttcaagc taagtgaagt catagaaaat gataccaaag agaaagtcgc attgacagag
    11161 gaacaggagc aagccttatt gtcatttatt aagacggaca acgtgtatca caagcattat
    11221 gatgatgtgc tgatactgtt aaagacagga cttcgtatct cggaactgtg cggactgaca
    11281 gtagccgaca ttgatttcaa gaatgaagtt gtgattatcg accaccagtt actaaagagt
    11341 aaggaacagg gctattatat tgaaacgcct aagacgaaaa gcgggataag gcaagtgcca
    11401 ttaagcaaag aaacgataca ggcatttcaa cgggttatca acagccgacc aaagataaag
    11461 tcgatagagg tagacggaca cagcggtttt gtgtttatca atccgaaagg taatccaaaa
    11521 gttgccattg attataacgc cttatttatc cgtatggtaa agaaatacaa caagcaccac
    11581 aaggacaatc ccttgccaca tattacaccg catacgctac gccatacatt ctgcacaagg
    11641 ctggcaagca agaacatgaa cccgaaagat ttacagtata tcatggggca ttcaaacatc
    11701 agtatcacaa tgaactggta cgctcatgcg tccatagata ccgcaaaatc agaggttcag
    11761 cgtctaatcg catagaagta tttaccacga ttttaaccac gattgacagg gaaaatataa
    11821 gaagatagac ctagatatgc gaggtttacc acaaaagcaa aatgcccgta gagccgataa
    11881 aataaggctt tgcggacatt tgagaagata taaaaagata gtcaaaaaga catatataat
    11941 ttataataat tatgactctt aattaaagta ggtgcccata tgcttgtttc ttttagtatg
    12001 gttataagat tttttctgac aattttatta tcactgatat taacacctgt attcaaaatc
    12061 atttcagtac aaacaggtat ggtcgacaaa ccaaatgaaa gaagaataaa taaagttcca
    12121 atgccttcag cgggcggact gcctatcttt atttcatttg ttatatcgac tttattctta
    12181 ttccgtaaaa ttatccctca atcgtatatt gtaccgatct tgattgcttc tttagtaatc
    12241 atagtcacag gagtgctcga tgataaatat gagctgacac ctaaacaaaa aagtataggg
    12301 atcttgattg cttctcttat tatttatttt gtagcagata tacgtattga ttccttcacg
    12361 cttcctttta ttggatatat ccaactaggc tggcttagtt ttcccgtaac gattttttgg
    12421 atcttcggta tcacgaatgc ggtcaatctg attgacggtt tggatgggct ggcggcaggg
    12481 atttcattga tcggtttaat tacgatagga atcattggat attttttcct ccatgcttct
    12541 acagtgtata ttccagttgt tattttctgt cttgtagcaa gtattatcgg tttttttcct
    12601 tacaattttt atccggcaaa gatttattta ggcgatacag gagctctatt cctagggttt
    12661 atgatggccg tcctttcact acaagggctg aagaacgtga cttttgtttc atcgatttct
    12721 ttgctgatcg tcatgggagt gccggtaaca gacacgtttt ttgctatcat taggagaaaa
    12781 gcaaaccgtg tttctttttc tacagcagat aaaaaacatc ttcatcaccg actaatcagt
    12841 ttaggcttta ctcataaagg tgctgtcctg acgatttatg cgatggcttt gatgttttct
    12901 ttcacagcta tggtcatgaa ttatactgga agaatcggaa cgatcatatt gattattgcc
    12961 atgttgtttg ctgcaatttt attatttgaa ttgattggtc tgatcaatga gaaacatcag
    13021 tttattttaa aaacattgcg atttttaggg aataaagagt accgtacgca agtaaaacag
    13081 aaatatttga agaaatggaa ccgtcatata gatgaataac aaattaaacc agccgatcct
    13141 tattagtatt gtgacggcaa acagtgataa aatttttcgg acactagata attttatttc
    13201 aactgtaaaa gatgaaacag cagtaaaaat ccgaattttt gacaacaatt cacttcccga
    13261 gtacaaaaaa agactaacag agtataggaa atatccctac atcgatatct attttcatga
    13321 tgaaaattcc ggatttggtt atggacataa tcacaatctg atagctagcg attctcgcta
    13381 tggcattatt tgtaacccag atattttagt ggatgaagag acagttacag cattggtctt
    13441 gttattgaaa gaacatccgg aatgtgcgat gttagcacct aagattctta atgaagatgg
    13501 aacaactcag cacctcatcc gtgagcagct ggctgttttt gattacgttt tgcgctttgt
    13561 gcctttcaaa tgggtcaaaa aaaagtttga caaacgactg gctgtgtttg aatgccgagg
    13621 attgcctact gatgctaata gttatgtacg gatgatctca ggtagtttta tggtagctga
    13681 tattgataaa tttaaagaga taaaggggtt tgatgagcgt ttcttcatgt actttgaaga
    13741 caacgacttg tgtttgagtt ttgaaaaagc aggttacaag ttattgtaca caccctttta
    13801 tgcagttatc catttttacg ggaagggtgc gcatcgaaat gcaaaactgt ttcgcgtgtt
    13861 tttgacttct atgatgaaat ttttcaataa gtgggggtgg cgttttttct gatgaaacca
    13921 gaaatattag tagtcgttgt gctttatcag caactattca gtcaatctcc agcttatgga
    13981 ccattaagca aagcacttag cgaaaagcaa attcagctta ttatttacga taatagtcct
    14041 caaaggcagc aaaatgagct gtttgaaaaa gaaaatatcg tttatcatca tgatccgcaa
    14101 aatcctggtt tagcggtggc ttataatttt gcgttgtctc aagcagatga aggaacacgt
    14161 tgtctcgtca ctctggatca ggatacgagg ctagtcgacg attattttga actattgcgt
    14221 aaagtaacct ttacagatga atgtgttgct gcagttccga tgattttttc tgggagccga
    14281 caagtttctc ccctatattc agatcgttat atcaatcgta cagctcaagc agtagaagtt
    14341 gaaggcccaa cagctgaacg aatcatggca atcaattcag gtgttgcctg gtctgtcaaa
    14401 tttctaaaaa agattggcgg gtttaatcct gctttttctt tagatttttt ggatcattgg
    14461 ctgttttgga aagtggatca gttggaaaaa actgtggaga tccttcctgt acgaatggaa
    14521 catgatcttt cggttttaga ctatgaaaaa gtttcaagta atcgataccg ttctatttta
    14581 caagcagaaa atcgatttta tcatgaatat gatcaaaggc atttatccag tcaccgacga
    14641 caattattgt taagaacagc taaacagttc ttgaccgtca aaaaccggca tatctggcgg
    14701 atgactttgc gctcatatgt taagaattgg aaggtgtgaa ttcgtgcgtt cggtttgtat
    14761 agctaccttt aatggaggca gatatttaag agagcagtta gatagtattt tatctcagct
    14821 ttcagcagaa gatgaagtag tcatttctga tgatgggtca gtagatgata catgggatat
    14881 attaactgaa tacgcagaaa aagataagcg aatccagctt ttttcggggc ctcgtcaagg
    14941 attgatcgct aattttggtt atgcgatcca gcagacgaaa ggagatctaa tctttttggc
    15001 agaccaagat gatgtttggt tggagacaaa agtgaaaaag atcactgact attttgagca
    15061 gaatccggat cagctagtag tagtttctga tttaatcatt gtggacagcg agctgcaaga
    15121 gatccatgat tcgtattttt cgtttcgaaa ttccaaagaa ggatggctta ataatgtgat
    15181 aagaagtcac tatattggtg ctggtatggc tttccggtct tctttaaaac ccgatatttt
    15241 gccgatcccg tcagaagtgc cgatgcatga tatgtggatt ggtttgctgg gaggaaagaa
    15301 gactgggttc ctaagagaac cgttaactct gtaccgaaga catgatttaa acgcgagtga
    15361 gattgaaaca cattctaaat tacggcaaaa aatttcttgg cgtgttcatc tgattacggc
    15421 gttgatcaaa cgaaaatggt ttaaacgttg ataaaagatg tttaaatcct taatatttcc
    15481 atgacaaata taacaattga tgagataata acaaagtgaa atttgaaatc aaaaaggaga
    15541 gcagatatcc atgaagggaa tcattcttgc tgggggcagc ggaacacgtc tgtacccttt
    15601 aacaaaggca acatcgaaac aattgatgcc gatttatgac aaaccaatga tttattatcc
    15661 aatgtctact ctgatgttgg cgggaatcaa agaaattctg attatttcaa cgccacaaga
    15721 tacaccacgt ttcaaggaat tatttggaaa cggaaatgat ttaggactgc agatcgaata
    15781 tgcagtacaa gaaagtccag atggattggc acaagcgttt atcattggag aagaatttat
    15841 tggagatgat agtgtctgct tggtattagg ggacaatatt tactatggtg gcggtctgtc
    15901 taaaatgttg caacgagcag cttcaaaaga tacaggcgcg acagtatttg gctatcatgt
    15961 caatgatcca gaacgctttg gtgtagtaga atttgatgag aatatgcaag ctttgtcgat
    16021 tgaagaaaag cctgctcagc caaaatcaaa ttacgctgta actggccttt atttttatga
    16081 caatgaggta atttctatcg ctaaaggtat caaaccttca gaacgtggag aactagagat
    16141 tacggatgtc aataaagcat atttggataa aggaaaacta tccgtagaac ttatgggacg
    16201 cggatttgct tggcttgata caggaacaca tgaatcattg cttgaagcat ctacctttat
    16261 cgaaacaatt gaaaaacgtc agaacttaaa agtggcttgt ttggaagaaa ttgcttaccg
    16321 tatgggctac atcgataagg aacaattgct ggcccttgca cagccattga aaaaaaatca
    16381 atacggtcaa tatttattga atttggccgc tgaataagga gtccttacag atgaaagtaa
    16441 cagatacaaa attaacagat gtcaaaatcg tagaaatgga cgtctttggc gatcatcgcg
    16501 gtttcttcac agaaagttat tcaaaagcaa aatttgcaga acatggattg aaatatgact
    16561 ttgttcaaga caaccattca ctatcagctg aagctggtgt ccttcggggg cttcatttcc
    16621 aaaaaggaga agctgcacag acaaaattga ttcgggtagt cactggagca gttttagatg
    16681 tagtagtgga tatccgcaaa ggtagcccga cttatggtca atgggacgga tttatcttat
    16741 ctgaacataa tcatcgacag ttgcttgtac ctaaaggata tgcccatgga ttcgttactt
    16801 tgacaccaaa tgtgaacttc ctttataagt gtgataatta ctataatgca gaagcagatg
    16861 ggggcatcgc atttgatgat ccagatttag cgattgattg gccaattgat ccatcaagag
    16921 cgattatgtc ggaaaaagat caccgtcatc cgacattaaa agaatttgaa gcagaaaatc
    16981 catttgttta cggagaaatc taagaattaa ggagaaattt tcttatgaaa aacatcattg
    17041 ttaccggagg tgccggattc atcggctcta atttcgttca ttacgtggta aacaatcatc
    17101 cagaagtgca tgtcactgtt ttggataaac tgacttatgc aggaaacaaa gagaacttgg
    17161 ctggacttcc tagcgatcgc gtagaattgg tcgtaggaga tgttgcagat gcagaattag
    17221 tggaccgtct agtaaaagaa gcggacgcag ttgttcatta cgcggcagaa tcccataacg
    17281 ataattcatt aaaagatcct ttcccatttg tacaaacgaa tatcattggt acgtatacac
    17341 ttttagaagc ttgccgcaag tatgatgtac gctatcatca cgtatctact gacgaggttt
    17401 acggcgatct tccattacgt gaagacctgc caggacatgg ggaaggcgaa ggagaaaaat
    17461 tcactgcgga aacaccatat aatccttcaa gtccatattc ttctacaaaa gctggttcag
    17521 atctgttagt aaaagcatgg gtgcgttctt ttggcttacg tgcaaccatt tcaaactgtt
    17581 caaacaacta tggtccttat cagcatattg aaaaatttat tcctcgccaa gtaacgaata
    17641 tcttaagcgg tattcgtcca aaattatatg gcgaaggaaa gaatgttcgt gactggatcc
    17701 atacgaatga tcattcttca gcagtgtggc tgattttgac gaaaggcaga attggcgaaa
    17761 cctatctgat cggtgcagac ggtgaagaag ataataagac cgtgatggaa ttgatcttag
    17821 aaatgatggg tcaaccaaaa gatgcgtacg accatgtaaa cgaccgtgca ggacacgact
    17881 tgcgttatgc aatcgattcg acaaaattac gggaagagtt aggatggaag cctgagttta
    17941 cgaacttccg tgatgggttg gctgacacga tcaaatggta cgaagaacat gaagactggt
    18001 ggaaaaaaga aaaagaggcc gttgaagcag catatgccaa aaatggacaa taatacagag
    18061 aaaatgtcac tgtattaatg gaaaaacaca tgtgaggcag gcgctcgcct gtctcttttt
    18121 taaaataaaa atcaaggagc ggataatcat atgtttttat taactggagg aaatgggcaa
    18181 ctaggtacag aattgcgcca tttattagat gaaaaaaatc tgcaatatgt ttcaacagat
    18241 gcaaaagact tggatatcac agatgccgag aaaacaatgg cttacatcac agaattaaaa
    18301 cctgatgtta ttttccattg tgcagcttac acagcagtag ataaagcaga agaagaagca
    18361 aaagaattag atgagaagat caatgttgat ggtacaagaa atgtagcact tgcagcaaaa
    18421 gctgtgaatg ctcaattcgt ctatatcagt acagactatg ttttcgatgg aaaaaacaaa
    18481 aatgtagaat acgaagtaga cgaccaaacg aatccactaa atgaatatgg tcgtacgaaa
    18541 ttattaggcg aaaaagcagt agaagagatt ttagaagact attatatcat acgaacttct
    18601 tgggttttcg ggatctatgg acacaatttc gtcttcacga tgcaacgcct agcggaaacc
    18661 cgcgacaaac tgactgtagt aaatgaccag tttgggcgac caacttggac acgtactttg
    18721 gcagaattta tggtatatgt catcgaagaa aaagcaccat ttggtattta tcatttgtcg
    18781 aacgaaaata gctgttcttg gtatgaattc gcaaaagaaa tattgaaaga tacagatgta
    18841 gaagttgcac ctgttacgtc agaagaattt ccgcaaaaag caacacgtcc gcagtattca
    18901 gtcatgagcc tgaaaaagac agaagagtta ggatttgtca taccaacttg gcaagaagca
    18961 cttgcgcaaa tgctggaagc tgccaaaaaa atgaataagt aatttccttt tatcaaatag
    19021 aatttggagc atgatatgga aaaacaaaca agaagtgcac gacgaaaaga aaagccaaaa
    19081 gcgaaccagg cagattcgaa tttggtgctt gacctgtttc taaaactccg ctatcttatt
    19141 ggcgttttag tcatcgtggt catcgttact tttaatttaa acggaagttc acttggtgtt
    19201 tgggataaat atgtgtcgca aagagacgat gggaaaaaaa ctgatgtgat ttttggacag
    19261 aatcgggaag tgcggtcaga cgaatggctg gtgcagacac ctttttacct ctcacaagct
    19321 gaagaggact ttccgttggt gaacgaggat tattcattaa acggacaaaa catgatcatt
    19381 gcgtataatt ctcctgtaaa ggatattacg gttatcggaa aaccattcaa ctggggattc
    19441 tttttcctcg gaagagatcg aggactttcc ttttattggg cgatgaaatt agtcgtcatg
    19501 gtcttgcttg gattcgaagt actgatgata ttaacgaaga gaaaaaaagc tctatcgcta
    19561 atcggtgcat ttgcgctgac attttctcca gcagtccagt ggtggttcat gcaacatgtg
    19621 ggcgatttga ttttctttac tttgggactg atgactgctt tttatcatta tttctacaat
    19681 catgataaaa aatggctacg aacgttgatg atgcttttgg tggttatttt cggtattggg
    19741 tttattttag tgatttaccc agcccatcaa gtgatgctgg cgtacttgct gattttttat
    19801 tttgttggcc tgcttattta ctatagcaag aaagtttcat gggatctgtt ggatgtagtg
    19861 ttgattggag gggcagtttt atttattggc ggagtcatgg ttcatttctg gctaacgtca
    19921 aaagacgcat tgttagcttc tttgaatacc ttatatccag gaaaacgggt aagtactgga
    19981 ggaaagtgga cgattggcga atttttttct ttccttacaa attggaaaat tccttttgaa
    20041 gatatcaact attcgaataa ctctgaagtg gccctgttct atcacttttt tccaactgta
    20101 ttcctagcaa gtccatttgt gttatttggc aaaaaagata gcgaacaaaa gttactggga
    20161 cgtattttga tgattttttg tctgttttct atcttttgga ttaccgttgg gttgccaaaa
    20221 tggctagcag aaatcactct gctgtcttat gttcctccat taagagccat ccttactttt
    20281 agttttgcgg cttgtttatt atcgatctgg tttatcgctt atatttggag agaagatgtt
    20341 attcctattt ggtataaatt cattttgttg gcagtaaatg catggtctta tttctatgcg
    20401 attacgcatt cgaaaatgga taattatttt tcggattttg aaaccatcgc agttgctgtg
    20461 ttgggaacag tgattttagc ttttgcatta tttggctgga gacgcttgtt ttacctcgct
    20521 tttgccgcct tagttatcgt atctggcttt ttcgtcaatc cagtcgtaga aggtacagga
    20581 gcgatttttg aaaaaacact ggcaaaagaa atccaaaaaa tcgatcaaca agatcctggt
    20641 aaagtttggt tgtctgaaga tgaattatat aacttcaccc caacattggg agtgaaatcc
    20701 ttcaatacag tacgctttta tccagatata gctgcatgga agaaaatcga tccgaaagaa
    20761 gaatacgaga agtattataa tcggtatgct catacaagag cttttatcgc taaggaagat
    20821 acaaagttca ttttagatcg tccagatatg ttttcggtca cgttgaattt tgaagacgca
    20881 gaaaaattag ggatcgacta tgtgatcagt aaacgaccat taactgatta caaccaatta
    20941 tatgaagcgc agttcacgca gctatatgga ccggataaag acggttatat gatttttaaa
    21001 gtagaatatc cggattatcc agatgtacca caaacacaaa ctcaggaaaa tcagctagtc
    21061 gtacagtaat aggctagctg agaataatcc tgaaatgtta gtagaaagga gagtggagat
    21121 aattcaagca atcgtacaaa aatttgtcaa caaaatgagt gtcggtttct tgcttttgtt
    21181 actgacgcta gtcttttttg tttggacagc agggttaggt tttccagcaa ctttgtttat
    21241 atataacaat agttcattac ttatcgcttt tagtgtggct attttgctca ttttaaatgt
    21301 ttataaagca aaaggcgtcg attttcttta tctaggtgtt gcgcttgccc ttttcatttt
    21361 cttttcttac tttcgggaat taagaaatga gtctttattt ggagacttac tgtttccttt
    21421 gattatttta ttttgtttag taattaaatg gatcgagtgg acaaaatggg atcgcggtat
    21481 ttatctgatt gtcttttcgg tcttcctcgg aatcacgtta tatcgtgtat ttacagagat
    21541 ccaagtacca gaaggacaaa gcatctgggc tccaggcaat tcgctttctg atatttggat
    21601 caatacgaat ataatcggaa gttctttgat gactcttgct ttattgatca gtggatttgc
    21661 cagttctttt gaacgatggt atgtacgaat catcggtgca gtagcagttg ttgcagcttt
    21721 tctcgggatt tgggtctgcc aatctagagg tgcattagtc gcgttgattg tttttgcgat
    21781 attggatctt ttacctaaat cgttgatgcg tgtcattcgt gcgccattta ttgcttacac
    21841 ggttacgatt cttttagctt tgccgatttc ttatctggcg gctgtctctg aaaaagtcaa
    21901 tttgtttacc ggtcgagaag atatttggca taaattctat cagacgctag gagaaaaatc
    21961 tgaacaaatt ttactaggaa tgaaaacatt tatcttccaa cgaggaaacc aatttttagg
    22021 aaaccacaat agttataatt ctattttgaa tatctatgga ttgataggat ttgggattgc
    22081 tgctttgctg cttatccttt ttattggtcg cttaacgttg aaagcagatt tatccaacgg
    22141 gcagatgact tttatctggg ccttttttgc ggtgatgatg cagtcattta tggaggatac
    22201 attgacttca tacccatggg ttccgattat ttatatcctg ttggctatgg ccgttcatcg
    22261 atatgatgaa ccagaagttg cggaggaatt ctatgttatg gaagaggcat atgacgatat
    22321 gacttatgat gatacatctt atgaggaaca accagatagc gctcattctt ccaggatcca
    22381 acgctatcat tgataggcac aaaatacgag agaggctgtg acaaccgtcg cagccttttt
    22441 tggtttattg caattgtcta gcatcttctg taaaatagaa acgttagaga aaatcttgta
    22501 tcatagaaaa ttaagaaaga aataagaacg cagctcggta ccaaaaatat ggtaaaatgg
    22561 cacttgactg taattcactg aaaatcgctt ggaggaacac aaatgtttaa agatttgtat
    22621 ttatttatga aggacattta tcagaacaga aaattattgc tacagttttc gatcaatgac
    22681 ttcaaatcaa gatatgcagg atcgttttta ggaatcttat gggcgtttat caatccgcta
    22741 tttactgtat tgatttattg gctggtattt ggtgttggac tgaaagcaca aatgatcgat
    22801 gcaaaatacc catttatcgt atatttagtt accgggatga ttccctggtt cttcttctca
    22861 gatgcatttg catcaactac ggttgttttt cgggaatata cttatttagt aaagaaagtc
    22921 gtattcaata ttcgtatctt gcccacgacg aaaatcctat ccaatctgta cacccactta
    22981 ttcttcattc tgattggcat agctgtcgcg cttataaatg gtatatatcc ttcagcaatg
    23041 tctttacagc tgatttatta tttattttgc atgtgtgctt tcttgacagg attgacttgg
    23101 ctgacggcat cgatccaacc atttttacct gatatcatgc aattaattac gatcgtgctg
    23161 cagttgatca tgtggacatt accgatatta tggagcccta atcagtttga ttcaggtctt
    23221 gtaagcatat tgaaattaaa tccgctgtac tatgttgttc aaggttatcg tgagtcattt
    23281 ttaagtgaag cttggttctg ggagcatgga acatatactt tgtatttctg ggttttcacg
    23341 ttagtaatgt tcgtaatcgg ctctgcagtg ttccgtagat tgaaaccaca tttttcagat
    23401 gtgctgtaag gagaatagct atgacagaat atgcaattag actaaaagat atcacaaaat
    23461 cttataatat gtacgcaaaa ccttcggatc gatttcgtga agccctcaat ccttttaaga
    23521 aatcctatca tgatgtattt tatgcgttga aaaacgtgaa tgtagaaata aaaaaaggtg
    23581 agatgatcgg tttcgtggga gaaaacggat cgggaaaatc tacaatgttg aaaatcatta
    23641 cgggagtact gacaccaaca tccggcacga tggaaatcga aggaaaaatc tcagctttgc
    23701 tagaactagg atcaggattc aatcctgagt attctggcta tgaaaatatc tatttaaatg
    23761 gaatggttct aggattttca agagaagaag tcgatgaaat ggtcgatgat atcattgaat
    23821 ttgctgacat cggagaccat atttatcaac ctgtaaaaac ttattcaagc gggatgttcg
    23881 ttcgtctagc ttttgctgta gcaatcaatg tgaatcccga tattttgatt gtggatgaag
    23941 cattggcagt aggcgatctt gaatttcaac taaaatgtat ggaaaaattt acagaaatca
    24001 agaactcggg aaagacgatt ttattcgttt ctcatgatat cagttcgatt cgtcgttttt
    24061 gtgatcgttc ctattggttg aaaaacggag aagtcgtcga atatggcgat acgatggaag
    24121 taacgacgaa ttatgaaaac tttttaaaga aaaaatcagt taaaacagtg gatcggaata
    24181 aaaaccaagt agaacggttc gccgctccag atatcgtcga cgtgacgaaa gcggaattgt
    24241 tggataaaga caaaaatccg gtggatatgc tggaacaagg agaaaaacta tacgttaaag
    24301 taacttatga agtaaaagat gatacaatca aaaatccggt tttaggaatt gcgctacgaa
    24361 cagtcgacaa tttttatgta tgcggactta atactctact agatggtatc aagattcctt
    24421 ggaaaaaagg agagaatatc ttttatctgg agtatgaaaa gttaggtttg ttagctggtg
    24481 aatattattt tgacgttgcg gtctttgaag aaaatgcaac ggttcctttg gtatataaga
    24541 caaagtacat gaacttgttt gtcagcggtt cttatatcgg agaaggcatc gtggtcttag
    24601 accataaatg ggaagaaggg actcatagca atgaaatatg attttgaaat ggacctagat
    24661 gaacaaagca gtgtgggaaa aattgccgca cagatcaaac caggaagtaa agttttagag
    24721 tttggtcccg gaaacggccg attaacgaaa catttaatcg gagcaaaaca atgtgaagtg
    24781 agcattgttg agttagataa ggaattgttc gattttgtca gcgaatttgc tcaagatgga
    24841 ttttatggtg atatcgaaag ttttgagtgg gcaaactatt atgctggaca gacatttgat
    24901 tacgtcttgt ttgcggatgt tttagaacat ttggtagatc ctggaaaaac attgaagaaa
    24961 gtcagagaat ttttgaatga agaaggagag atcctgatta cattccctaa cttggcgcat
    25021 aattctgtca tgatcgattt gttcaataac caattgccgt gggcttctta tggtctccta
    25081 gatgaaaccc ataattcttt ttatactcat gatggcttcc aaaaagtttt tgaaaaagcg
    25141 ggattattca ttaatattga agattatttg tacttagctg taggtgatac agaattaaaa
    25201 tcaacttatg aagaattgcc ggaagctgta cgctatgatt tcaaaatgcg accatttggt
    25261 gaagtctacc aatacttttt ctcattgatg aaacatccag tagcacaaag ttccattgca
    25321 gagccacaaa attctaatta tgtaaaagtg ttagaagtaa cccagcaaac gaaacaagat
    25381 gaaacaatcc aacaaatacc attcaataat ttcacagggg aaaatgagac actaagtttc
    25441 cccgtatcag aaacaacaga aagaatggtg tttcgcttcg cgcaacaacc tagctttatc
    25501 gaattcagcg cagaagctgc cggagaaaaa ctaacattta tcgattcgaa tgctgtagtc
    25561 aaaacagtaa atgattgtta tttgtttgat gggaaagaat taccagagtt cgttctaacg
    25621 gatatttctg ggaaagaagt gactatccat tgtcactatc gctttatcgg ggaattgaca
    25681 ccaacaatga aagaattgtt ggaaacgatt cgtcccatgg ctgaagtcac aaagcagctt
    25741 tctgagaaaa atgacgaatt agaaagagaa aatcatcatc ttcttgagga aaatacaaga
    25801 ctagaccata cgttaaaaac aaccacaaat cgctattgca cattgttgga aagtgatgaa
    25861 tggacaataa aacatagact aggacgacgt aagaaagaaa cttcgaaaaa aatccaagaa
    25921 aaagaacttt ctatatgtat tgacgagaaa atctgggatg cagaaacaaa aatattaaaa
    25981 atcatcggat ggggaatcgc taattcggat cgccagccct tgtcctataa gttatcagct
    26041 gaccaatcgc catttttcga agcaattcct gtttcacgag aagaagtcaa tcaagcagaa
    26101 cagctcgcaa aaggaacaga agcgggattt gagttacgaa tcctttgcga gcaagaacgt
    26161 tcattcttag tggaagcagt agctcaaaat ggccaatcat ggatcattga aatgtaaata
    26221 atgattaact tataaagata aggagtaaac gaatcgtgca aaaaaaagaa attgccgtat
    26281 ttatcgatca aatcactcgt gaacgggcca ctggcgattt gcttattgtg ggctgggcaa
    26341 ttgatgaagt gaccaaagaa atccctacga taaaggtaga aaaagaaaat gtgattgctg
    26401 aagcaacaca tgtcgtaaga ttggatatca atcatttata taatcttgat gttaagaccc
    26461 aaagcggttt taaggtacgt ttatcaggga aaatgagagg aaaagccatc ttagacttcc
    26521 aaacagcgag acatcaaaat ggcatagctg tgaaattaaa cggtaaatac ccttatgatg
    26581 acggcattga atcttcatgg gaaagaaaaa aaagattact gaaaaaaggg ataaattatg
    26641 caaggactca tggcgtaaaa aaagcgatcc gtcgggtcaa attggaattg aagccaggat
    26701 cgatcgacta tgcagagtgg atcagtcgtc atgagaaacc agatttgaaa gagcaaagga
    26761 aagaagcaca aggatttgcg taccgtccat tgatttccat acttatgcct gtctataacg
    26821 ttgaaatcaa atggctcgaa aaatgcattg attcggtact ggatcaaacg tatgatcatt
    26881 gggaactatg tatcagtgat gatgcttcta ctgatccagc tatccgaaag tgtctggaat
    26941 cctatcaagc aaaagatgat agaatcaaag tcgttttccg aaaagaaaat ggacacatca
    27001 gtctggcaac taattctgca ttggaaatag cagaaggaga atttatagca ctcttagata
    27061 atgatgatga attaccgcca tttgcattat atgaagtggc aaaagtgcta aacgtacatc
    27121 cagaactgga tgtgatctac agtgacgaag ataaaatcga tgcagatggc aatcgctttg
    27181 atccgcattt caaagcagac tggtcgcctg atacattgat gggaaataat tatatctctc
    27241 acttaggcgt atatcgaaca agcattgtta aagaacttgg cggtttccgt aaaggctatg
    27301 aaggttctca agattatgat ttggtccttc gtgtgacaga acaaatccct gcagatcata
    27361 tttaccacat tgaccgagtc ttgtatcatt ggcggacgat cccaggatca actgcaagta
    27421 atggcgaagc caaaagttat atctatgatt ccggagtgaa agcattgaca gatgccctgt
    27481 ctagaagaaa catcaaagga agcgtacgtc ctggcagaat ttctggattt tatgagattg
    27541 cttatgacgt cttgcaagag gatttggtca gtgtgatcat tccaacgaag aatggctatg
    27601 aagatctaaa aacttgtgtg gattcgatca tcgaaaaaac gtcttattca aattatgaaa
    27661 tcattattgc ggataacgga agtacagatc caaaaatgca agaattattt gcagaataca
    27721 agcatcagct gaaagaccgc tttatcgtag aattgattga cattccattc aattattctc
    27781 gaattaacaa tttagcagca gaaaaagcaa acggcaaata ctttttattc ttgaataacg
    27841 atacagaagt gattgagcca gattggatga cggtgatggt ttcttatgca cagtttgatc
    27901 gaatcggctg tgtaggagca aaactgtttt atccagatga tacaacgcag catgcaggag
    27961 tattattagg aatcggtggt gttgcagggc atgcattgaa taactatgat cgaacacatt
    28021 gtggttattt cggccgattg gtcattgacg tcaattactt agcagtcact gcagcttgta
    28081 tgatggtcaa ggcagctgac ttcaatgctg ttaacgggtt tgatgaaaca ttagaagtag
    28141 cattcaacga tgttgacttg tgcttgaaag tttatgaact gggtcgttac aatgtctatg
    28201 cacatcaagc agaattgtac catttcgaat ctaaatcaag aggttatgaa gatactccag
    28261 aaaaacaaag acgttttgct ggtgaaatca aaaaaatgca agataaatgg ccagcatata
    28321 ttgcgcatga tccattttac aatgataatt taacaaaaga aggaatcggc gacttttcgt
    28381 tgagaccaga ttaaactata ataaaaagct gttatgttgt gattcgctcg cacataacgg
    28441 ctttttatag ttttttgtca aaaaaaggca gaaggtgccg actcaaaaaa ataagtcgag
    28501 gttgggacag aagtgtttaa ctccgagaaa taagaagaaa ttcacgaaaa ttgcttttca
    28561 aatttttgtg aatttcggct tatttaagaa gaagttgctt ctgctcccac cgtttattcg
    28621 tttttaaaga atgagacaaa agtgtttctt acttttgtcc cacgctctta ttcatgctca
    28681 gagcgccaat agatacaaaa tcatagccaa agtttcacga accctagctg tcaaagaatc
    28741 gatattttat tttaatatag gctattttaa aataaatggt ttaaggtatt cctctacaaa
    28801 agccactcta tcaattatca tgggtttaaa ataagaagtg atggagataa ccagattgtt
    28861 cttagcgtca atataaagaa catttccact attaccaatt gctgaatata tttcgttctc
    28921 agaatctaat acccaccata aatagccata tctcatattt tgtaagtctt ctaaagcact
    28981 ggttctaggt ttgaacatct cgtttatcca catgggtggt acgatttgtt ttcctttata
    29041 catcccttta tttaggcata atacaccaat ttttgccaga tcacttgccg ataaacacaa
    29101 accatatcct gccgtcccga tatttagtgg atcacaaaac cagacattgg ttttaggaga
    29161 cttatccatt gtaaactgct tatgttcttc agctgtttca gcataataat tgacatggtt
    29221 tggtatccct ataggatcaa atagatactt attggcaaaa tcaacagttg ttagcttact
    29281 tgtctgatac aacaagccag ttaatatgtg taaacagaca gtttgatagt tgaattcgcc
    29341 ggttatacct tttcttcctc ccaataaatc tagtgatgtt tttgtccaat cttcacttga
    29401 acagactttt gtccatggat cgcctttaca tttgtagggt gctttcattg ttagcaagtg
    29461 cttgattgta atagcgtaaa tagttttctc cccgcgtttc actttatact ctggaaaata
    29521 atctaatact ttatcatcga tacttttgat taatccttgc tctaaagcaa tgccaatcag
    29581 caaagataca atacttttcg ttgctgacat gatatgacaa gtatcgtctt ttttataacc
    29641 attccattca tctgtataaa cttctacccc atccttatat gcgacaattt gacatatatt
    29701 tggttgtcga aaaccaataa aatcatgcaa ctcttgttta ttcataagat attacctcac
    29761 tttcttctat aagcataatg tcattaaaaa tcgatttcaa ttttttcgat tcttcacgta
    29821 atacaggtat tcttatggac tagacagcgc tttgggaaga tggattctct gaaaaatata
    29881 aaggttcact ttatgagtgg ataaaaaaag cagcaaatac ttcgacttct ttaatttacc
    29941 aacattagtg aaaatcgatt catctggaga tttgtaattt agagtccttg tcttgattag
    30001 aggtgtataa agctttttat tagacatttt taaattccat tacaatttgc ttataaacta
    30061 ggtttttaaa ggtgactatg gtaagataat agagatatta ttttgtgatt aggagtgtat
    30121 atatgaataa aaatggagaa tggagtgctg cacgacggat attcattata ttaatggatg
    30181 ttattgtata caatgcagca atatatagta gtttcttact gaagtttcgt ggagagatcc
    30241 cattacgaaa tttagaaact ttccaacact cagcaattat tatttcagtg atttttattg
    30301 cgttgaacat tttgttgggt gcatatgttt tttataatcg aatgatcagt gacatcgtgt
    30361 ttgtcacagt catcggtcag gtattgatga cactagggat catggtagtg acttttgcgg
    30421 gccgctggtt tgcttttcca cgtcttgtta tcttactttc atttgttctc ggtacgcttt
    30481 tcttaagtat ctatcgtatt ctcgtatata aactttattt acgcgtaagt cgagataaaa
    30541 aggtcgtcat tattgggtta gaaaaggatg tcgcaccagc aatccaaaat tttggttcaa
    30601 agaaaaacaa caaacataaa gtcgaagcag tcattcttga taactattat gcaaacatca
    30661 aaaatatgat taaagacatc gatattgtct atcttgcttc tcatatcgaa gaaactgaaa
    30721 aaatcaaaat ctatcaatta gttactaaaa atgaaaaaaa attgtttttg aatacaacat
    30781 ttgaaaactt gacattgatc aatccaaata ttatgaattt cgaagatgaa agtattattg
    30841 aagcatctgg atttagaatc caacctgaat atgaactatt caaacgtttg tttgatatca
    30901 tcgtttcact tgttttatta gttattgctt caccatttat gttattcaca gcaattttag
    30961 tcaaagtgac atcaccggga ccaatcatct ataaacaagt gcggatcaca aaaaatcaaa
    31021 aggaattttc aatctataaa ttccgctcga tgaccgccac agccgaagca aaatctggac
    31081 cagttttagc taagagcaat gatgcacgag taacgcctgt aggtaaattt attcgagctg
    31141 tccgctttga tgaattacca caaatcttca atgtgctgaa aggcgatatg tcgatcgtag
    31201 gaccacgtcc tgaacgtcct ttcttcgtcg atcagttcaa tgcagaaaac ccttattact
    31261 acttacggca taatgttcgt gctggtatca ctgggtatgc acaagtctat ggaaaatatg
    31321 tctctgatta caacagtaaa ttacgttttg atttacttta tatcaaaaaa tattcattga
    31381 tgcttgattt aaagatcttg ctgcaaacca tcaagatcct atttgataaa atgtcctctc
    31441 aaggacttga agaagacgaa aatgtgatct cattggcaga aattgctttt ccgaatgaaa
    31501 aaatctttcg ctagttggga ggcgtaaaaa tgaacaatcc gaaattcagc ataatcgtac
    31561 cagtatacaa tgcagaagca actattggtc gaacgattga tattctaaaa gaattggatt
    31621 atgaagagta cgaagtcgtt ttagtaaatg atggatcaac agatcaaaca caggaaatca
    31681 ttcaagaact gattgaaaat gatgaacgtt ttgaattgat tactacgacc aatcaagggc
    31741 ccggattagc aagaaacgaa ggaataagac agtcaaaagg agaatatctc ttattcttcg
    31801 atgcagatga cacgccagta aaaacgatct tgtcagatta tgatcatttg ctagaaaaga
    31861 gtccaaaagc ggatcttgtt gttagttcgt ttgtttttcg tacaatggac gagggaagaa
    31921 tcgtttccga aaaagaaaac ttagttacag aatgtcacta tctaactcac gaagagttta
    31981 taaaagacat gtatcagtta atgaatgaac agttgatgta tgttgtatgg aacaaatgct
    32041 atcgtagcga tattctgaaa aataaccaaa ttctatttaa aacttataat agttgtgagg
    32101 atcgaatatt taacttacat tattatgaat actgtcatca agtgatcatg aacccaaaag
    32161 tagaatatat ttatgaattt gaaggtggga aggggatcac taatcaatac cgacctaaca
    32221 agttcgaaac atttaaagaa ttctattcat tagcaaatac tgtaacagac gatattaata
    32281 aagacggtat ggcggcgctt cttttaaaag ggacaacttc agttattttt tctatttata
    32341 gtacctctgc aagaacttca aaagagaaga aagacgaagc aaagcagata ttgagtgatc
    32401 cagtgatccg agaagccaag caaattgcta agacggattc ttcagcaaaa aaaataacaa
    32461 agttgcttta caatatgcca gctccactat ttttatctgc tgtaaaagtt ggaagcttcg
    32521 ttgaagtgaa aatgccaggg ttaatggctg ctttgaagcg agtatattag ttaatggagg
    32581 aaaatataat gaaaagaatt ttgcattttc agggacgaat gggtttaggt ggagcagagt
    32641 ctttcatgat gaatttatat cgtaaaattg atcgtacaaa ctatcaattt gattttttga
    32701 tttatgaaga ttatgcagat gttcaagact atcattcaga gattgaaaga ttaggaggcc
    32761 gtatttttgt tgtacctaat cctaagaaaa atatttttaa atatttaata gaagtgaata
    32821 agttactaaa aaaagaatct ttttctatag ttcacaatca ggtttatttt ggcgggggaa
    32881 ttaatttatg gttagccaaa aagaatggaa tcagacagag aattgctcat agccatgcaa
    32941 ctgaagatgg aaaatctcaa aatattgtaa tgaatgtatt gcgtaaattt ttaaccaaat
    33001 tgttgttaca aaatgcaaca gactaccttg ccgttagtca agaagctggt gaaagtctgt
    33061 ttcaaaacca cccctttgag atagttcata atggtattga tttagagctt tatagtaaaa
    33121 attcagaagc taaggttaat aagagaaaag aattggatat ctcaatgagt acttttgttg
    33181 tgggaaacat tggacgatta gagaaacaaa aaaatcaatc ttatttgtta gagatttttt
    33241 tagaaatact aaaaatgaat tctgattctt acttgatttt agtaggtgaa gggtcactta
    33301 gaaataaact gaaagccaaa gcagtagaat tggatataga gaaaagagta aaatttttag
    33361 gagaaagaaa cgatattccc gagttattat ctgtgatgga tgtttttgta atgccttctc
    33421 tttatgaagg tctgccaatg gttggattag aagcacaagc agcaaaatta aaattagtct
    33481 tagcagatac tatttccaaa gatacaaagt taacaaataa tgtggatttt gtatcattag
    33541 atgaaacacc acaagaatgg gcaaaaaaag taataaaaga gccgtatgct aataaaataa
    33601 cacaagaact aaagagttat gatgtttcgt acactactga acaaatggag agtatatata
    33661 gtagagatca ttaaaaatgt tcaagatatt ttaggagtga ttatttttga aaatatgtta
    33721 tttgatattg gcatacaatg atattggcaa cttaaagaga ttggtcaatc gattgaacga
    33781 aaatgcagtt tttattattc atatagataa aaaaactgat atagaaccat ttattgaagc
    33841 atttaaatca tatgataatg ttgaattttt atgtaataaa aaccgtgtta aaatttattg
    33901 gggtggtttt tccattgtac aagcagaaat caatttagta aagagagcat tacaaaatga
    33961 gaaatattta aaatatgtat tattatctgg tgctgattat ccaatcaaag ataatgagta
    34021 tatttataat tattttaaaa agaatagttc agtggagttt attcgtggaa tagatctaga
    34081 tcaaattaaa cataaagaat tttattataa acatatagat gtatatcaaa aacatgatta
    34141 tcctagaatt aataggaata acacaactgc atttaaaatt tttagagcta taattaatcg
    34201 ttgtctgagg atgattaaac ttcccccaaa aattagacac cataaatttg atttgtatca
    34261 tggttctcaa tggtgggctt tgtcgaaaga atgcctaaca gaattaatac aaatgtatga
    34321 acaaaatcaa caagactacc tgaattttaa aataggtatg tttgccccag atgaaaaatt
    34381 ttttcataca ctttttttta attcctcgtt caaaaataaa aatgttattg gaggaccaga
    34441 tttaccactt gaattgaaaa atattgaaga aactacttta caaacttcga aattagcaaa
    34501 tattcatatt attgatcctt ccatgaacaa atggtttgat gaaagggata tagatcaaat
    34561 aaaagaaagt gaaaaattat ttgtaagaaa agttaaatcg gattactctg ataaactatt
    34621 aaatagaatt gataaagaaa ttttgaaagt tggaaatata gatgaataga atagtacctg
    34681 ttttagagaa gagtttatta agtcgagatg cgtttcgagt aataaattta atcatttgtc
    34741 tgctttattt tatgcctagt acttttaatg taactaatat cccgatgaaa atagcttttg
    34801 cttggggtgg aattatagtt ttgtatgagg tttttataaa gaaaaatttt tttaaaatgc
    34861 gtttttcttg gctactgatt ggagcaatga ttagttttat cttaactata atcattaaca
    34921 gagaaaattt tttaattcca tctatttata attttggata tttgctgatt actttgatag
    34981 taatttttcc tgcagacttt tcacaaagtg aagaggaaaa aaagaaaaaa atggtgtatt
    35041 ttaataatgt tttcattatc ataatttttt tagctgcgct aatatctatc tatcaattta
    35101 tttttttgat ttcttatcat gtcccaacag gaacgccagg attacttgca agacaaggtt
    35161 ttattgaaca tcggttattt ggtgtctata caagtccaaa tgttggagct atgtttggat
    35221 atacttctat tattttaagt ttaattagtg tattaatttc aaaaataaca aaaacgattc
    35281 gtgtttttta tatgatgaat tttatcgtac aaatatttta tattacactt tcttcgtcta
    35341 gaggtgccca ggtagtaatt tgttcttttt tagtattatt tcttttgttg tttgccaatt
    35401 caaaatttag aaagagcatt agagaagtac tacctgtaaa aatcaaatgg atggtaagca
    35461 tattattagt tctattggta tatttttctt ttggtactaa ttatgctaag gattttttag
    35521 caacaattcc tgtatcgatt gatagaaaag tagaagttat agagtcaaat gaatcagata
    35581 aaactccact tccagaaaaa gaagtaatat tacagcattc tagtgataac tccgaaattt
    35641 cagctggtcg ttttacgatt tggaaagctg cgcttaaagt tataagacca actttgttat
    35701 ttggttatgg agagaccgat ttctatggga atagcgatgc aaaatttttg aaaaaagtag
    35761 atcttgatac tacagatgtg aatgaactaa aaagagcaca tggaaacatg cataatggat
    35821 ttcttcaagt acttgtatca agtggtataa ttgcttttat atgtatctat gctttctatg
    35881 tgttaaatat ctttagttta ctcaaaacat tttttagaag taaagtgaat tatgcgtttc
    35941 ttggtattgt tttaattttt atactatcta tttttataga tgaaatggtg gaggctcatg
    36001 tacttttcaa taagcgcgat gtcatttcaa ttgttttctg gtattatttg ggaagcattt
    36061 cttacttgta tttaaaaaag gagaattaat atgaagacag ctttcattgc ttggactcct
    36121 ttacatttga ttaatatatt aaatgtttat caaaattttt accgagaatc aaaaggagat
    36181 ttatttattt attctgaatt tgaaaacgct agaagatata gtgagcgtat aaaagaatta
    36241 gggctattta atgatgttgt ttttgtgaat caccggaaaa tcggttcttc ctttaaacgt
    36301 aaaattaact tgttaactaa ccataatcaa tttttctcgg atgatttatc cgtttatgat
    36361 gaaattttta tacaggggga aaattatttc acaaaaatac ttttctccaa tgtttacaaa
    36421 aaaaatccag atgtaaaact aaattatata gaagatggtt tgggtactta tttgaagaag
    36481 agtatatttt caacaagtaa aaacgttcaa agagttttta aaatattaaa taaaaatagc
    36541 atcttcaaaa aaaaaattga cgattatttt gtctattgtc cggaattgtt actttatgat
    36601 gtaaaaaata taaaaaaaat tcccaaaata gatgaaaaca gtaaattgat gaaaaacata
    36661 caatcaatct ttgggataga agaagttttt gtcggagata aatgtatctt ttttgatcaa
    36721 cctttattat ctgatggtta tggcatagat gaaacagata ttttcgctaa agtaaatagt
    36781 atattttctg gaaaaaaaga aactttaatt aagcttcatc ctagagcaag gacaaatcgt
    36841 tatggtgaaa aaaacatatt gaattccagt ttaccgtttg aagtcttgct acttgaaaat
    36901 gacttctctt caacactttt gattagtcct atatctacaa tttctttttc accatctatg
    36961 atgtttgaaa agacgatcaa ctctattatg ttggctaaat taattttaaa tgaatataca
    37021 gcattatctg aagataaaaa agaaacattg acaaatattg ttcttttctg tgaacattat
    37081 aaccgtctat cagaagaaaa aattttactc ccagaaaact gggcagaatt aagaaagttg
    37141 gtagagtatg ggattattta acacactttc caagtcaaaa ttagttaagt ccagtttctg
    37201 gtatactata gggaattttt ttattaaggg aatttcattc ataactattc ctatttttgt
    37261 aaatattact actcaagcag aatatggttt gattaataat ttcacttcat ttgtatcaat
    37321 tttttcgatt cttgttgggc taagcctaaa ttcggcaatt aataatgcaa gttttgacta
    37381 taaagatgac ataaatgaat ttatgtcatc ggtactttct ctagctacac tttcgttaat
    37441 tgtgttctta ttaataggga acatatattt tttgttttca aatgcttttt ttgatatgaa
    37501 ccaacttgta tttaatttga tgttattaca aagttttgct agttttgtaa ttagttatat
    37561 ccagtcttat tttacgatta actttaacca ttttaaatat ttgattttat cttttatatc
    37621 tacttttttg aatattgcaa tctctgtagc tttgatgcag acattatatt ttgatgataa
    37681 atatgttggc agagtagtcg gcggaacact gtcatttgtg ttgataggtt tagtaattta
    37741 tttaagaata atgataaagg gtgctcattt ttttgataaa aaacagtgga gatacgcttt
    37801 aaaaatctct ttgccgctaa tcccacattc cttagcaaat atagttttag cacaattcga
    37861 tagaattatg attaattctt atttaggtcc tgctgcgggg ggaatatatt cctacattag
    37921 taacataggt attattctaa gcgtaatatg gatgtctact aataacgcct gggttccatg
    37981 gttctatggt gagatgagta aaaataatga aaaaaaagtg aagaaagtta gtaactatta
    38041 tttagtagtc tttactttga ttacgatgat tgtaatggta gtttcgattg atttagcaaa
    38101 atttatggct ccgaaagact attattctgg gttatcttta gtggttccga taaccttagg
    38161 ctatttcttt cagtttttat atagtttacc agttaatgct gaattttatg agaaaaaaac
    38221 atcgtttatt gcgattggta cagtagcaag tgctatagtt aatatactat taaacatgat
    38281 tttcatacct aggttaggaa taattgctgc tggatacaca accgtattta cgtatttttt
    38341 actttttatt tttcattata atatcgctaa aaaaattacg aataaacaat tatttgacac
    38401 aaaaaaaata tgtatcataa taatttttgt atcaattttt tctttgatac ttcatatttt
    38461 aatcaatcag atgttgattc gttacgtttt gacatcatta ttgataatta gtttagttat
    38521 atatttttta aagattaaga atcgaattat agatgactat aattcatagg aggagatata
    38581 agtgtttaaa ggaaaaacaa tattagtaac tggcggaact ggttccattg gaagtgaaat
    38641 tgttcgtcag cttttaaaat atgaaccaaa agctatcaga atttatagta gaggtgaaga
    38701 aaaacaattt tatatgcaac aagagctctc aaatcacact aatttgagat ttttaattgg
    38761 tgatatcaga gactctcaaa ggattgatta tgcatgtcgt gatgtggata ttatttttca
    38821 tgctgccgca atgaaacacg ttccagcaag tgaatataat cctatggaag ctgtaaaaac
    38881 aaatgtgatg ggaactcaaa atgtaataga tgcagcgatc aaaaataatg taaaacattt
    38941 tgtaggtatc agtacagata aagtagtgag tcctactaac accatgggtg cgacaaagtt
    39001 attgagtgaa aaattaataa tagctgccaa tcagtataaa ggaaaaacag aaacaatatt
    39061 ttcttgtgta aggtttggaa atgtcatggg gtcaagtgga tctgttattc ctctttttag
    39121 taaacaaata aaaaacaata aagatattac tttgacagat gttgatatga cacgatttat
    39181 gatgtcaata ccggatgctg caagattagt tctgtctgct gctatgaatt caaaatttgg
    39241 agaaacatat gtcttaaaaa tgccggcaat caatatttta actttagctc aatcattaat
    39301 aaaaatatat aatgatacac atgatgaaaa atatagaggt gaaataaaag ttgtaggtat
    39361 caggccagga gaaaaattat atgaagagct aatgactaca gacgaaattg aacgctcata
    39421 tgaaaatgat aaaatgtata tcattccacc acactatcat gctactgacg aactgtacaa
    39481 agattatgaa aaaattaaaa tcactgcata ctcttcagat gcaacagaat taatgagtgg
    39541 acaggaattt attagaatcg caaaagagaa taatgtcgtg acttggtaag gagttttatg
    39601 atgaaatcag aagtatatgt aattgcagaa attggtgtaa accataatgg aagtctagat
    39661 ttagctttag aaagtattga taaagctaaa gaatgtggag ctaacgcggt taaatttcaa
    39721 acatttaaaa cgaataagct agtttccaaa aaggctccaa tggcaaaata tcagaaggat
    39781 aatcttaaag aggacagttc tcaatttgaa atgctaaaaa aattagaatt atctcaatct
    39841 gattttatta gaataaaaga ttattgtata caaaataaaa ttgatttttt gtctactcct
    39901 tttgatgaag aaagtgcaga ctttctaaaa caaattggtg tacaaggatt taaaattggc
    39961 tcaggagatt taacaaattt accttttctt agaaaaatag atatgtatgg gttgccagtt
    40021 ttattatcta caggtatggc tgatattcat gaggtcagtg aggctgtaga ttgtttcata
    40081 gatagtccag ttactatttt acattgtact tcaaattatc cggctagttc tgaagatatt
    40141 aatttattgg cgattaacac attaaaagaa atgttcggga tacccgttgg gtactccgat
    40201 cattcattgg gatatgatgt tggtatttgt gctgttgcga tgggtgctaa ggtaattgag
    40261 aaacatttta ccttggataa ggaactacct ggtccagatc ataaagcttc tttagatcct
    40321 caggaatttg cagattttgt aaagcatatt agaaacactg aaatattttt aggtgatggt
    40381 gttaagcgag caatgccttc tgaacttagt acaaaagaag tatcaagaaa aagcctagtg
    40441 gtcactgaga atttaaatgt gggagatatt cttacagaga aatctcttac aataaaacgt
    40501 cctggaaatg gaatagctcc taagttttta tatcaatata ttggcaaaaa agttaaaaga
    40561 ccaataagtg cagatagtgt tctgcttgag gaagatgttg aatgaaaaaa atacttatag
    40621 taagtggaac acgagctgat tatggaatat ataaacctgt tgctgagaat ttactacaag
    40681 ataattggga tgtatcattt gttgtttctg gaatgcattt atcccataaa tatggattta
    40741 ctaaagaatt gatcttagct gacggattta gaattagtgg agaagttcaa agtttgtttt
    40801 tagagaacaa taagggaaac atggctcggt ctgtggcatt agagataaat ggtttcacaa
    40861 atatatttga acaaactagc cctgattttg tattattact aggggataga ggagaaatgt
    40921 tggcagctgc gatagcttgt ttgtatcttg gaatcaaaac agcacatatt cacggaggcg
    40981 aagtgtctgg tactgtagat gaatcaataa gacatgccat aacgaaaata gcatctgttc
    41041 attttgctgc tacggaaaaa agcaaagagc gtttaataaa aatgggggaa gattcttgga
    41101 gagtttttcc cgtcggagct cctagaatag atactatttt aaataataga ttacctagtt
    41161 ttagagatat aaaagaaaaa tatcatctaa aatttgaaaa gaaaaaatac gttttgcaag
    41221 tatttcatcc agttgtaacc gaactagaaa atatagaaaa acaaatttta gctttgatca
    41281 attcaatgga acaacaatct caaccaatta tttgcatttt acctaatagt gatgctggta
    41341 gcgaaattat cagaaaaatg taccagaaat atttaaaaac ggatattatt tatattacga
    41401 atttagagcc ggaggaatac ctgactatat taaaagagtg caaatttatg atcggaaatt
    41461 cttcttctgg gataattgaa gctgcatcat tcaaaatacc agtaataaat ttaggaacca
    41521 gacaaaatgg acgagaacaa tctaaaaata ttataaatgc aaatctaaat gaaaatgaaa
    41581 ttgaaactgc tttgaataaa atacaagatc ctcagtttat aaaaagcttg aaaaatgtta
    41641 agaacatcta cggtgacggc aacagttcta gaagaataac aaaaacattg aatcaaatat
    41701 tgaatgatgg ggaagatatt aagtggattc aaaaacaaat agcttattaa aatatactag
    41761 tgatccatac attattattg gggctggcgg acacgcaaaa gtcattattg aaaccttaag
    41821 attagaaaat aagttaatat atggattttt tgatgataag caaaataaaa tgcaagatct
    41881 gaaatatctt gggaaaataa acgaattgaa tagctgggcg gatagcaaaa aaaaaatcta
    41941 taaatttatt gtagctattg gtgactgtgt agtaagaaaa aagattataa aaaaattgaa
    42001 tatgccaagt gagcaatatg gaatagctgt tcatccaagt gctatagtgg caaaagaaat
    42061 ttcaattggt tatggaactg ttatttttgc gaatgctgta attaacccag atgctgtaat
    42121 tggagagcat gctataataa acacaggtag cattgttgag catgattgta gaattaataa
    42181 ctatgttcat ttatctccag gtgtatgctt agcgggtgga gtacatgtag gtgtaggaac
    42241 tcaaatagga attggttctc aatgtatcca gatgaagaaa attggatctt ggtgtatgat
    42301 aggcgcaggg agcactattg ttaaggatat tccctcacat tccttagctt atggcaatcc
    42361 agctaaaatt aagaaagaag gaattaattt tgaattctag aattttatta tcaagtcctc
    42421 atatgggagg aacagaagaa aaatatgttg ctaaggcttt taaagataat tggatagcgc
    42481 cattaggtga aaatgtggat aaatttgaag aaagtattac aaaatatact ggttctaagg
    42541 gcggagcttc tgcgttaagt tcaggtacag ctgccataca tcttgcctta agactgctta
    42601 atgttggaaa aaacgatatt gtctttgctc cttcatttac ttttatagct acagtaaatc
    42661 ctattttata tcaaggggct gtaccagtgt tcattgactc agaacctaat acatggaata
    42721 tgagccctgt tgcactagag agcgcattag aagaagctga aagaaacaac caattaccta
    42781 aggcaatcat cgtagtgaat ttatatggtc aaatggctga ttatgaacga attttagcta
    42841 ttgcaaacca atttaatgtt ccagtgatag aagatgcagc ggaatcgtta ggttctactt
    42901 ataagggaat ttcgtcaggc ttatttggga caattgggat ctattcattt aacggtaata
    42961 agatcatcac aacctcaggt ggaggagctc tagtgtctag tgataaaaaa tatgttgagc
    43021 attcaagatt tttagcaaca caagcaagag atcaagcacc gtattatcaa catagcgaaa
    43081 taggttataa ttaccgtcta agcaatattt ctgccggtat cggacgtgga caaatggaag
    43141 tattgaatga tagagtagct aaacgaagag aaattttcaa tcgatataag gaagcttttt
    43201 ctggaattga tagaattgaa atgatgccag aagtggatgg catggtgcca aatcgttggt
    43261 tgtctacttt aacgatcaat gattataatt ctattgatca agtagttaac gtaataaata
    43321 aactaaatga aaaaaacatt gaaacaagag ctttgtggaa accactacat ttgcaaccag
    43381 tatttcaagg ggtaaaaatg tattaccatg ataataatct tagtgtgtca gaaaagttat
    43441 ttaatagcgg cttatgctta ccttctggaa gtaatatgac agatagtgaa caagaatttg
    43501 ttattgatga gtttaaaaaa atattcaagt aggtgtgata ttttatgaac ataggaatta
    43561 ttggtttagg ttccatgggg aaaagaagac ttagactcat tcaagaacac tttaatgata
    43621 ttttactatg tggtgttgat actaatgagg cgagacgaaa ggaagttgaa aaggaatttg
    43681 gaataccaac ttataatagt ctaacagagg caaaaaattt gtttgaaata aattcagttt
    43741 ttgtttgtac atcccctata acccatgaat ttattataaa agaggcttta aatttagatt
    43801 gtaatatctt tacggaaatc aatttattaa atgaatatta tgatgaaata atcgaagtag
    43861 ctaaaaagaa agatagatta ctttatctat cttctacatt tttgaagaga aaagaaattc
    43921 aatatattaa gtctaaagtg acgcataata aaaaaatttc ttatcaatac catgtaggac
    43981 agtatttacc cgactggcat ccttgggaag attatcgcaa tttttttgtt tcaaacaaaa
    44041 aaactaatgg gtgtagagaa atattcgcta ttgaattacc ttggattata gatacatttg
    44101 ggaaagttaa atcgtttact gtaatgaccc agaaattatc caatcttgat attgattatt
    44161 cggacagttt cactcttatt attgagcatg aaactggtat agttggaact ttaagtgtag
    44221 atgttgtttc aagagtagct aaaagaaatt taactataat tggtgaaaag attttaatag
    44281 aatgggaagg taacccggat tctctatttt catggaatga agaaacttct agtatgacag
    44341 atattcaatt gtacgatgag gttatgcatg ataataatta ttcacatact attattgaag
    44401 atgcatattt agaggagatt aaagaatttt tcacgctttt ggaaaagaaa atggaacccc
    44461 aatatacttt tgaaaaagat aagtatatta ttaacttaat taacgacatt gaggtaaatt
    44521 aatgatgaaa gtaatttttt ttgggttagg gtcaattgga aagagacatc taaaaaatct
    44581 aataagctat ggaaaaaaga attctattaa ttttgatata acagcttata gtagcagtgg
    44641 aaaaaaagag tttgaagaaa taacgtatat tcaaaataga gacgatttgg atacacatta
    44701 tgatatagct tttattacaa atccgacttt taagcatctg gaaacactaa atgtaattgt
    44761 tgaaaaagtt gattacatat ttttagaaaa acctgctttt tctgagagta ttgatcttac
    44821 tcaatataat tatgattaca aaaatattta tgttgctgct ccactgaggt ataaaaatat
    44881 catggaagtt gttcgtaata gtattcaaag taaaaaagta tattctgtaa gagctatttg
    44941 ttctacttat cttcctgatt ggagaaaagg tactgattat agaaataatt attctgcctt
    45001 taaatctatg gggggaggag tagaattaga ctgtatacat gaattggatt atattataaa
    45061 cctatttggt ttccctaaat cagtaaaaaa acagtttggt aaatattcga atcttgaaat
    45121 taacagtaat gatttagcaa catatatatt gagatacgat gataaaatta tagaaattca
    45181 tttagattat tttggaagag ttcctacaag aaaatttcaa ttgtttactt tagatgaatg
    45241 tatcaatgtt gacttattaa ataataaaat aagttttgaa gaaaacattg ttaaagaaat
    45301 gcctgaatct gctaatgata tgtatgagaa ggagttgaaa tatttctttg aaaacgtagt
    45361 aacaggcaaa gaaaactgga atgatttata tcatgcaaac gaagtattga aaatagctga
    45421 ggagaaataa atggaaattt tatttactat ttgtggtaga gctgggtcta aggggtttaa
    45481 aaataaaaat ttgaaatatt tggcaggaaa gcccctagtc catttcgctt tagcaatgat
    45541 agatatctat caacaaaaac atcctgaaca taattgcacg acttgtttga atacggacag
    45601 taatgagtta gtagaattga cgactaagtt aaatccgtct gtgaaaattg tagaacgtaa
    45661 acctgaatta gctacagata ctgtagggaa aattgaagtg atacgtgatt cattcttaca
    45721 actagaaaga gaagataata tatttgattt aattatagat ttagatttga cttcaccttt
    45781 acgtgaagtt tctaatcttg aagaattaat agatgaacat ctaaaaaatt tagataaaga
    45841 cgtctacttt tcagttgttt ctgcaagacg taatccctat tttaatatgg taaaaagaat
    45901 tgaaaatgaa gttactatag ttaataaatc aagatacaca tctaggcaac agacacctga
    45961 agtttttgaa atgaatgcct caatgtattc ttttaaacct gaatttctaa aaaaaagtaa
    46021 ttatattttt gatgggcaat gtgggataat aaaaatgaga gattatctaa ttttagatat
    46081 tgatagtgaa gaagatttta aatggttaga atttttgttt cctaaatttt tagaagattc
    46141 ttcggagctt caagatatct ataattattt atatcggagg taaaaggatg agctgttatc
    46201 ttatcaccgg tggggctggc ttcattggtt ctaccttagc caatcattta ggagaagaac
    46261 atgtggtaat cgtcgtcgat gacttatcaa tgggaaaagt agaaaatctt gatatgacga
    46321 aaaatatcac ttttattgag ggagatgtcg ctgagaaatc cttgatggaa gagatcatga
    46381 aagctaataa atttgattat atctttcatt tagcagcagt tgctagtgtg gcagattcag
    46441 ttgcccgacc agtagaaaca catcgtgtga attttgaaag tgtattaatg attttagaat
    46501 tgatccgcaa gtatcaacct gatttaaaac ggatcgtgtt tagttcttca gcggctgttt
    46561 atggggatga accgacttta ccaaaaaaag aagagtccgt gattcgccca ttgacgcctt
    46621 atgcggttga taaattcgct gcagaacaat atgtgctaga ttattgtcat ttatatgatg
    46681 tacccggtag cgcagttcgt tttttcaatg tctatggtcc aaatcaaaat ccgaattctc
    46741 catacagtgg tgtgatttct attctcgtag atcgctataa gaaacaaatc gtaggagaag
    46801 caacttcatt tacattattt ggtgatggaa gccagtctag agactttgtt tatatagatg
    46861 atgtaatcca agcattactt ttagttgcga atgaggaagc tgcactgggg aaacaattca
    46921 atgttggaac gggtaaagca accacacttt tggaattgat tcatgcaatc aatgaaattc
    46981 tcggtgtaga attgacactt gaatacaaag aagagcgttc gggtgatatc catgactctc
    47041 tagcagatat tactaagatc cagtcaattg gctatcaacc gaaatatggt attttaagtg
    47101 gaatgactaa ttatttgaaa actgaaatca attaaaacat actaagataa gattagaggg
    47161 taaattcagg ctctttgtca ataaggactg atgagttttg taaaatcaaa tctgggatag
    47221 aa
//
LOCUS       DADQDV010000017        45761 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.017, whole genome shotgun sequence.
ACCESSION   DADQDV010000017 DADQDV010000000
VERSION     DADQDV010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 45761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45761
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.017"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(125..1933)
                     /gene="uidA"
                     /locus_tag="J8S10_000993"
     CDS             complement(125..1933)
                     /gene="uidA"
                     /locus_tag="J8S10_000993"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003479936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HAZ9629593.1"
                     /translation="MLYPIMTETRQVIDLSGLWRFKLDTNDDLQEELALEPINEKESY
                     PISVPSSYNDLFETENIRNHVGWVWYEKEVTLPKRLLEERLVLRFGSATHEAKVFLNG
                     KFITQHKGGFTPFESEINRFVKDGNNRITVAVNNIIDDSTLPVGIMKETVQENGDIKK
                     ENLVNFDFFNYAGIHRPVKLYTTPKDYISDITINTRITDLDASVEFNIDTEWTGKILI
                     AIYDEEAQLVAEAEGKKGMIQLKNPIFWEPLDAYLYSMKISLIDDNKVIDTYTEEFGI
                     RSVQVTNGKFLINNKPFYFKGFGKHEDSYVNGRGLNEAVNIKDFNLMKWIGANSFRTS
                     HYPYSEEIMRLADREGIVVIDEVPAVGLHLNFMATLLDDNVEKHNTWKEIRTENSHKT
                     VIKELIERDKNHPSVVMWSIANEPDSDSEGAKEYFEPLVELTKELDPQKRPVTIVTYL
                     KSTPDVCKVGDIVDVLCLNRYYGWYVSGGDLAHAKYLLKKELDGWMERCPDTPIMFTE
                     YGADTVAGFHDTVPTMFTEEYQVAYYEANHEVIDTCENFVGEQVWNFADFATSQGILR
                     VQGNKKGIFTRDRKPKMIAYYLQKRWSSIPNFSYKK"
     gene            complement(1956..3722)
                     /locus_tag="J8S10_000994"
     CDS             complement(1956..3722)
                     /locus_tag="J8S10_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HAZ9629594.1"
                     /translation="MTIKVDLRKKPYNLDEDAISWIEETIDSMTLEEKIGQLFVNMGS
                     SRDKNYLSNMVNQYHIGAVRYNPGTADEVYDQNYILQTESKIPLLIAANTEAGGNGAC
                     TDGTEVGVEVKIGATNDAKYAYELGRVSGIEASAIGCNWSFAPIVDINRNWRNPIISS
                     RSFGQNPDKVLELSLAYMKGIQESGILPAAKHFPGDGIDERDQHLSFSINSLGTEEWD
                     NSFGKVYSGLIEAGLPSIMAGHIHMPAYSKHFNPDLKDEDLLPATLSKELITDLLRGK
                     LGFNGLVVTDASHMLGMTGAMKRSELLPTSIAAGCDLFLFFNDPDEDFNYMMEGYRKG
                     IITDDRLLDALKRILGLKAKLGLHKKAKEQILLPKQEALEKIGLIENKSIFKEVADQA
                     ITLVKDKQDIWPIVPEKYKRILLVDVHGVKGGFGEVVAGNRPQAIDLLKQILSAKGFE
                     VEKYISPEEELKGLSQEEKIKNIAGIYAAKRPIKNLTKKYDLIINIANVNPGTVQRIV
                     WPASKGTPDIPFYIHEIPTIFVSVQCPFHLADVPQVKTYINTYDGKQETLEILVDKLM
                     GLSEFKGVSPIDAYCGLKDTFI"
     gene            complement(3735..4529)
                     /locus_tag="J8S10_000995"
     CDS             complement(3735..4529)
                     /locus_tag="J8S10_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAZ9629595.1"
                     /translation="MNNWIFCIDSDGCVMDTMTYKHNLFFGPIAAEIFDVHHREKFLQ
                     DWNNINLYSETRGINRFLGLVKTLEKNDVTSINRLKHWVSLTKELSNPSLKREIEYSQ
                     SEDLLKALKWSEEVNQQISQAKGLDKPFLSARDTIKALKKYGKIIIVSSANKEAVQEE
                     WERHELLSLVDELCCQDKGKKEDIIRSVIENGCDLDKILMIGDSPGDLEAANKNKVFF
                     YPILVNKEKESWENLRTDVLFKCLSGDYVDIEQKYIDTFWKNLTNK"
     gene            complement(4539..5915)
                     /locus_tag="J8S10_000996"
     CDS             complement(4539..5915)
                     /locus_tag="J8S10_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAZ9629596.1"
                     /translation="MERKFGIRDKIGYMFGDFGNDFTFIFASSFLMIFYTKVLGISGA
                     AVGTLFLVARFIDAVTDVTMGRIVDRSKATKQGKFKPWILRMSGPVALASFLMYQTSM
                     ISASMSVKVVYMYVTYILWGSIFYTSINIPYGSMASAITSITEERTMLSTFRNVGAAL
                     ASLVIGVLTPLFIYTRDDSGAQIVRGGSTFTIVAGIFSICALICYLICYKLTTERVRI
                     DQSQYKVSLLKSLKGLVKNRALLSIIGAAIFLLLAQLLIMSMNNYVFPDYYNDAQGIV
                     LMNFINPILVLIVVSPLTLFLSKKYGKKELASVGMFFSAIVYLILFLIKASNMYVFLI
                     LSSVGYMGLGVFNTVIWANITDVIDDQEVKSDQREDGTVYAVYSFARKIGQALAGGVG
                     GWTLSIIGYDSLANVQTGDVLEKLYNASTLIPSICFLIVGLILFFLYPLSKDKVLENC
                     ELLKQKHK"
     gene            complement(6035..6682)
                     /gene="eda"
                     /locus_tag="J8S10_000997"
     CDS             complement(6035..6682)
                     /gene="eda"
                     /locus_tag="J8S10_000997"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HAZ9629597.1"
                     /translation="MKKVEILSKLEAAGVIAVVRGKNKDEAIKAINSIIAGGIKGIEL
                     TFTVPNAEEIIKEIAKKYADQKDVIIGAGTVLDAFTARIAIMAGAEYIVSPSFDRQTA
                     EICNLYQIPYLPGCMTITEIKEALTAGVDIIKLFPGSAFGPSIVKAYQAPLPHVNIMP
                     TGGVSIENLEDWFEVGVVAVGVGGNLLASVEKGDFEEVSRVASKYIDKFYEIKNY"
     gene            complement(6766..8193)
                     /gene="uxaC"
                     /locus_tag="J8S10_000998"
     CDS             complement(6766..8193)
                     /gene="uxaC"
                     /locus_tag="J8S10_000998"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HAZ9629598.1"
                     /translation="MFLDKNFLLENEIAKRLFHKFAKHQPIIDYHCHLDPAYLLENKQ
                     YKNLTQVWLNDKGAGDHYKWRLMRANGIEEELISGPGDDYEKFLAFVKTVEKAPGNPI
                     FEWSHLELQRYFDIDLTISEKNAPEIWRRANEKIQTDSYRPKELLEMMDVKAICTTDD
                     PTDDLWYHTELSKQDNSFKVLPTFRPDKVWSIKSSGFSNYILKLSQTAAIPIKDFNGL
                     KQALSQRVDHFHQIGCRLADHGLNTYFYEIADEKILDNLLIKALAGKTDFHLSEIAQF
                     VTGIQLHLMSEYTRYGWTMQMHLNALRNNSSILKEQIGVDVGGDSMGDQASLTQNVVA
                     LFDTAEKSGCLPKTILYSLNPTDWLPLATAMQSFQGGMIQKIQLGCAWWFNDTAEGMR
                     QQLTTMAQQSLLSNFTGMLTDSRSFLSYPRHEYFRRVLCQLLSEWVKAGRIPDDEMYL
                     SQIVENICYRNAYNYFNFFEIGSRK"
     gene            complement(8267..9346)
                     /gene="uxuA"
                     /locus_tag="J8S10_000999"
     CDS             complement(8267..9346)
                     /gene="uxuA"
                     /locus_tag="J8S10_000999"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HAZ9629599.1"
                     /translation="MEMTFRWYGANEEKISLQEIRQIPAMKGIVGTLMDIPAGEVWPR
                     ERIKSLKDEVEANGLTLKVIESVNVHDDIKIGLPTRDQYIENYKQTIRNLAEFGIEVI
                     CYNFMPVFDWVKSDLDYRLDDGSSTLAYISKNIPTDPEEIIREVENSTNNFELPGWEP
                     HRLSQIKQLLEAYKEVDEEKLRENFAYFLKAIIPTCEEVGIKMAVHPDDPPYSIFGLP
                     RIVKNRDDLDWLCNVVDSPSNGITLCTGSIAERPDNDVYEILSEFCQRDRIPFAHVRN
                     IKYLSDNGLDFYEAPHKSEYGSLDMYKILKTMYDNGFNGYIRPDHGRMIWGETGRPGY
                     GLYDRALGAVYLNGIWEALEKGASK"
     gene            complement(9349..10980)
                     /locus_tag="J8S10_001000"
     CDS             complement(9349..10980)
                     /locus_tag="J8S10_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HAZ9629600.1"
                     /translation="MVSIKNWQNSIEEFNEMQILLPCFDVKEVKQEGQQHPVWLHFGG
                     GNLYRGFHAEIAQCLADQNELETGVVVCETFDEEVVEKAYHDYNNDILEIVMSGDGEL
                     KKRLLAVTADSLYCNPKNIADYQRVVKYFEDPKLQFTTFTITEKGYSLKDSKGQFFSV
                     VKADIKSGPSNPQHTMSIVTSLLYSRFNAGELPIAMVSTDNFSQNGQRFQDSIFTIAE
                     AWQKEGYVSEKFIAYLKDKEKVTFPWSMIDRITPNPSENVKEDLLMMGLEDLDIIHTK
                     KHTNIAAFTNTEVVHYLVIEDSFPNGRPKLEKAGVIMTDRETVDKADIMKVTTSLNPL
                     HTALAVTGCLLGYQSISAEMQDDDLVGLIKGIGYLEGLPVVENPGIIDPKQFIDEVIN
                     KRLPNPYIPDTPQRIATDTSQKVAIRYGETIKKYVEKDGNAENLTFIPIAIAAWLRYL
                     LAVDDQGENFVPSPDPLLVELQDKLSVLKLGEQDPSKIHCAVQEILENKEIFGLDLYQ
                     VGVGKKTEKIFCEMLVGPQAVRKTINKYITEVGGK"
     gene            11284..11955
                     /locus_tag="J8S10_001001"
     CDS             11284..11955
                     /locus_tag="J8S10_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAZ9629601.1"
                     /translation="MTIKTSLQNQAYQSIRRQIIYADLEPGKKVSEKKLEETLSIGRT
                     PIREALIQLRQQGLVDTIPQSGNYISLIDLDSAKNARFVREHLERQIMLECCAKMNNQ
                     KKRILETIISEQEKAVSQKNARSFFHNDNLFHKACFEIAEREEVWQWLENNNTHLERF
                     RWLRVKTEGLKWEKIMEQHYQLFEALTKQDPEEANFLTSLHLHLMLNEQNIVLATHPK
                     YFKNI"
     gene            complement(12680..13015)
                     /locus_tag="J8S10_001002"
                     /pseudo
     CDS             complement(12680..13015)
                     /locus_tag="J8S10_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313007.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(13112..13564)
                     /locus_tag="J8S10_001003"
     CDS             complement(13112..13564)
                     /locus_tag="J8S10_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629602.1"
                     /translation="MKSLEQEHMAFKQAMFKENIYLNHNYIRVSKACSPVLNMLGGGN
                     GLYHLLFVDVCWLIFLPDELVIVNEKITSKNEVFNYSLTRINYKEITKFSLEKVPFWG
                     EFCLKIKCNWKRMYFYIDGDDALTFGKTTFSSFNFQFLLKNNFYGLLK"
     gene            complement(13571..14119)
                     /locus_tag="J8S10_001004"
     CDS             complement(13571..14119)
                     /locus_tag="J8S10_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAZ9629603.1"
                     /translation="MKRIIKIFGVLGVFLLGLSTFVSTGTSVYATEKVNTVDLEIKNK
                     LVDELTFYFDTVGFLDEHGVYHIKDFGAIRERISQDNEQGRAARVFYEHIIVPRMEKV
                     DWKRYAGCVAINSLPGGGVAWAIGTQGDFIEALKAFNFEKAADLLLKIAEKQLGKAAA
                     KELAKVNIVAGIAAAAASCALE"
     gene            complement(14164..14496)
                     /locus_tag="J8S10_001005"
     CDS             complement(14164..14496)
                     /locus_tag="J8S10_001005"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629604.1"
                     /translation="MSEEKKEIVESLVALKDSLSKIEYVDRQEIQKLIDDTIIEIQDA
                     RCEGIKISVALSKVIEKMNRSLAFNGLKLDRQTSLIWDHLKDLYDKSKRSERTAVSIL
                     KGLWGMNS"
     gene            complement(14510..14740)
                     /locus_tag="J8S10_001006"
     CDS             complement(14510..14740)
                     /locus_tag="J8S10_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003653123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629605.1"
                     /translation="MCIGFVGVGLFVSTESASAAEWYNPIWYNPNIECQKGYPYGPTN
                     LKNGKCRVNWNGVVDSVITGSMDSALHGFTGH"
     gene            complement(14962..15504)
                     /locus_tag="J8S10_001007"
     CDS             complement(14962..15504)
                     /locus_tag="J8S10_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629606.1"
                     /translation="MKKGIILVFSWLCLIGLTGCHWFSSEKQKTQLRTTEETIEAVKE
                     TSGTLQSTESNSQIGSLEDETAQQMQIDEMTKNFLKDFARKWSNFTDVYKRNQAVRDY
                     MTDRCIKDNSIDVDPHVQMKTTGKLYQVTQDIENPDQYLLFGEETMNKVTQFVLLQLK
                     VDQEAQKIDAIKIYYVRSAY"
     gene            complement(15525..16616)
                     /locus_tag="J8S10_001008"
     CDS             complement(15525..16616)
                     /locus_tag="J8S10_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HAZ9629607.1"
                     /translation="MKKGCLGCLLFFILPFFLLPFFFSGELSEHGGEATGLAVAFNGE
                     YTEGLPIFSEIKGRGPITDEHAQAAVGAAVKYQLLPSVILSQLGYESAYGQSQSGRND
                     TNFFGITWFPGCPYPQGSARGIGGSEGGFYMKFPNLKACYDYYGFMVASQSNFNQCVG
                     NKDPGSCLLILGRGGYAAAGITEGSPYYRGAMSIITSYNLTEYDTFAIKHWNSLPTKK
                     TSLIAGKSKGNAKVLDRIIGRSVNNGECYGGTAWYVSQLGGPQLMGSGHMFAMLIGED
                     YNWTTYGWQVIMNPKPSDLQAGDVVNWQAGGALSPGIYGHTGIITDVSYGGQHFSSVE
                     QNAEQGRIMARYQRTYNQTKIRSLVRKVK"
     gene            complement(16624..18834)
                     /locus_tag="J8S10_001009"
     CDS             complement(16624..18834)
                     /locus_tag="J8S10_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629608.1"
                     /translation="MAYIKHKEKKWCVLFFLTIGFGLLFVGGLVYAAEKQVDQSIYEI
                     GKFHIDTFSSYLSDSEFSLGKMLFGANGTDFLKMMTNMFFSLSKLIWQGLDFVIEKLY
                     EGAAMNELIHQFFTFSDTIYSKIYDPIGAGIVVLYVLYLFTLRIFRGKHYAKMVFIRF
                     LFVVIFSMVWFGYGSNVPSKGEAFTKGLNDLSVEVEGFIFSATNSLDELATKDVNGVL
                     VPTTQKEAIQKVRQLYYKAAVVDPYILLNYGTTNLEELYQAEIEPQEFLAKEASSEEL
                     SDIETKVTTAAGEDRGKKKAYRVYIQPTKAVYKAVVGSMVPLLNLSIGLPLVVIGMIR
                     FIFQMLVLCLLLVIPFSLLASFVPVFDYMLMNTLKSFLGLMFQKSFYSVIILVAFLIY
                     NIVDDLIPMNTVFGFLGNMFVKALLSILLIVKRKDLLKKLGLGAADQTINNTKNIASH
                     SLSQMKQLPGQLSTAGQNLAIKGAGLAGNVYRATNPLASAAIHGFQKFQQKRTPQESV
                     KGRQVVNPFELGGRSNQALPYSGRHVRYHGVEPEMSSTKSKTEWNSGLSNGLIPNSSM
                     NSVRPKQQVQSLAQLSKQQGNNQRKPLLNKGIAFVGQSIPLPSGKVPVPQLTAAGSLS
                     QQIRQVKNQAKNGSYPAMQQLLNQYSVPNSSVATLSGNRSVQQPGQRSSESKPSISAP
                     KSLQPAFSSLDKPTEQSEKIEKDPKTLPILDAKPGTDFTLPKGRTVQKPLSKKG"
     gene            complement(18850..21378)
                     /locus_tag="J8S10_001010"
     CDS             complement(18850..21378)
                     /locus_tag="J8S10_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HAZ9629609.1"
                     /translation="MVLVKEPVKAFKKNCLLNGEDCIWAYYHVFPRTISKNTPKKTQE
                     IKEMMARLLLLLADYEDVELVMYPRTMNLRTKFDTLGKGFSPDSQAIGAYYAKETVTL
                     LEREGQVYRPSFILGIKVKEKATVESFHDVINLIWLDLAGSLARLFGLEVDDLETLFS
                     ESDPYVKEVTQLLYSFSIRPLVKKELLYLNRLQYIRGMAHKVEEQNNWEVLKDNQGTY
                     VRIPKEHKGLLQLEDELGSSYLALLPIGETPENMRNCDLFQFAQDLSFPAELRMKIHY
                     PRLKGQGGIGLKLNWLSERFKTEHKELVQNDEEPSERLLTVRGLVKHLKQRVDNGQPV
                     VDWIACFIVYGQTVEEVRQNSATVIQQLHTIIHIHRAKNDQRELFYKCLLGQPLGRQL
                     HWKHRTTVEAVGEWLFSAVSELGMESGWYIGRQDTLGDGGSRGEKTPLEELIYASNRF
                     VFLNLLAIAEGIKGALFDAPHVAVTGKTGKGKTFLVGLLFLYSSFMNVQSLFVDPKGE
                     KRKWFTKLIQDPYYQKHYPLFVEHLQKMSYVTLDATNPRNYGVLDPIVCLSRVDAKQV
                     AQDMIDELSPLGTNHLLKGAVLKGIQEVLVQKEAGQQVGLMHVVDYLEQMEQKEVREY
                     GEFLRLTVEDSILRLGFSYGENPGLDFNAKTTILEIQDLKLPNDNVRPELYTDADRKS
                     LCLMISLGRFCEMFGKRDSSKKTAIYFTEAWVFNNSNAGRSIIAAMARVGRSQMNQLV
                     LDTQFIGDLGSDKEKGNFGVVFAFDEDSEREKILNHLRLEVNEANLAEMSHMIKGQCW
                     MLDPYGRVGKLNVHSLFEEMTAALQTTEKTSHSQVEEQDTLIMQ"
     gene            complement(21430..21840)
                     /locus_tag="J8S10_001011"
     CDS             complement(21430..21840)
                     /locus_tag="J8S10_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629610.1"
                     /translation="MDWEPYDYSIVYAEPYRVQQITSNWRLPFPVALVNAATFLLVVI
                     FEYLFLRSFIGWVISFFPPAGVVFYIGLPYLCVLALAKLKPDGKKVHFYLWDWFCYMI
                     RMMNGDCVYYNWDKVSNNALEELLFVNKYVYLED"
     gene            complement(21853..22071)
                     /locus_tag="J8S10_001012"
     CDS             complement(21853..22071)
                     /locus_tag="J8S10_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629611.1"
                     /translation="MTLKGIVDFILTQGGYFLIMVVVYLGLRNFMKSKVGNALISIAA
                     GAAVYFFLNDPTRVFDAFGKIIEKLFMD"
     gene            complement(22068..23060)
                     /locus_tag="J8S10_001013"
     CDS             complement(22068..23060)
                     /locus_tag="J8S10_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAZ9629612.1"
                     /translation="MKKRQLRRKEKVYTEKVSKQKKIHSKKAVKWIWCLVLFLCFSGG
                     LAFFQSMKTKVQVSFLKDEIQQLQKKEVQSRSELTYTPEIESFMNRFVALYMNTFDNH
                     EQEQQRQETLKKEFYAQNFIQEPGSVSGVRKLTAASFIGLKEIETIPTASYKVTYDIR
                     SMNPESKKETSVTITQVLNLPFSISNKGCRIIAYPYFTALPKNTEKQRMITYDDTLYE
                     TVDASEAKDVEGFVEDFLDKYAKNNAKDMSYMMKEPEGLNQTAKVDQVEMKVLRYKET
                     KKPFIVKATVVFRDGDTSLLQKEQMTIVITKKTNQYYVEKLTHNWLDRKGEERK"
     gene            complement(23139..24050)
                     /locus_tag="J8S10_001014"
     CDS             complement(23139..24050)
                     /locus_tag="J8S10_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAZ9629613.1"
                     /translation="MKKTTLAVVTTLGISLFSFQLGSSLVYADETVETPKSEIVETLP
                     GEGLPDVETELNGGTTEKPAEPEQLQSEKPEKEPVTPEPEFPESTLPTDSIEEEGVHS
                     STTTDSSIVTTPEQSGTTSSSEKNTDSSSTEQPTMSSTSEEQKEEPKQPVEKSEAIPK
                     ENKPIVPAKEVTVSVTPSGEITTNTSQGMSVPIVTSNVEELTHIPTPTTPLKVAGDQT
                     IVGVKDGIPLIQDSEGNLVKDLSIPVKKLPSGNIEIKTADGKTKVLPKTGEEIHVALS
                     VLGGVLTSIAGFVGYKRKRKGIENEGN"
     gene            complement(24069..24413)
                     /locus_tag="J8S10_001015"
     CDS             complement(24069..24413)
                     /locus_tag="J8S10_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629614.1"
                     /translation="MWRLLFLVVCGMALFYVYRVYLYPRMERWTSWYRDPLKQRKGLK
                     RYRYELLVEFSDGRQAQYYFFANYPKYNTSELLIQLFKNNPYVGLEENGREFFYRSDN
                     ISAASMNKTRIA"
     gene            complement(24433..24989)
                     /locus_tag="J8S10_001016"
                     /pseudo
     CDS             complement(24433..24989)
                     /locus_tag="J8S10_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353559.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(25070..25570)
                     /locus_tag="J8S10_001017"
     CDS             complement(25070..25570)
                     /locus_tag="J8S10_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629615.1"
                     /translation="MKKIMIYVGAYWSRDPTVLENPEAVHYCLRQLFYLYKERLESLI
                     RQLPYTDRRLDELLLRYPAMYKRRKNRLLPEEYPIEKHELEGRFVAYFYDDVRMRLVE
                     QRMEIENDRYYFINYCKKRKYQVTDDFYDCILQDGEVILSKIAPSFRELVPIDFLKKC
                     HLRILP"
     gene            complement(25571..26116)
                     /locus_tag="J8S10_001018"
     CDS             complement(25571..26116)
                     /locus_tag="J8S10_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629616.1"
                     /translation="MNAYTTTEWLRLLDLKAAIEALNEKMVDLSYFRFRVPYIEQAVK
                     AGRYQEKENWQEIARLLEVRKGYEQELEELEFSRRKGRLEFIRFYRFSLPIPAILAVK
                     KGCDKMKIYENCVAALSSEKPLMEEISLVTVTWEMSRQPTEEQTYLSLEEIEIELEEI
                     GRYATCSTYCGSVISIAGVIV"
     gene            complement(26113..27369)
                     /locus_tag="J8S10_001019"
     CDS             complement(26113..27369)
                     /locus_tag="J8S10_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAZ9629617.1"
                     /translation="MTPIELKSYRKKLSAIHNISGDKKPLSQARFAQLMGCSKDYIRK
                     MEQGKRKIPEDFEQRIKERFRLYMKSGIDLRAMIDYLRLSFFGTDYKTVIQRVLRMDL
                     TEFETRPTGLYLFDCLSVRGNIWVFWHSKRTVTENVLVQFSGQGCREYEEVMREQQTD
                     WRTWLYSIWKNQGKLEAGYTRVQCSRFDIALDELWGLETEEHFDLFELLEKQKAGLLE
                     MDFKRFQNIGGCFLDDGYFRSEGLSLYFGSRKSPLFFNFYEKRFEIANREKISELEAL
                     TKYGIYNRYELRLANEKATQAVEAFILGDSPKRLGEIGVGLINAKLIVWDRLESDARI
                     VDKRWAKLFRSMEELDFTVKPEKFSLDRSERWFLKQVAPTLKLLQEADRILGRDFVQE
                     GIDNAELNDEQQNYLEWMGTSGGKIA"
     gene            complement(27730..28041)
                     /locus_tag="J8S10_001020"
     CDS             complement(27730..28041)
                     /locus_tag="J8S10_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629618.1"
                     /translation="MAESCYYRVATAIRMINPSLSSRTFYDWLNRIEQVTDYRFLRKE
                     RVFTGKVINQVLLTKKDIERLTRLYHYRVDLEEDLTLSIYRVFSPEKYSEITKLDHLI
                     L"
     gene            complement(28064..29374)
                     /locus_tag="J8S10_001021"
     CDS             complement(28064..29374)
                     /locus_tag="J8S10_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HAZ9629619.1"
                     /translation="MYLIPGISIVLYLLLVSGLILGLMHWSRLKEGYFASVYWRQLLV
                     RMLIDNRFVYTKKQVSEKQTREKMRLPKVYFYQKKQELVVSFPLDGGRFHERFLKMGH
                     LLSEVFLRDLIREEREKARINYVFLSDSGRIPIDQCIAENGRIHLMKTLDWVYDQSPN
                     MLIAGAIGGGKTYLLYSLIQACLSVGTVDICDGKAADLAALGDVDVFKGHVFYKINEE
                     MIICLRNALKEMNQRYAYMKTMKDPKYEPGKNYAYYGLPPHFIFFDEWAAFYGSLDME
                     ARNRVDKLIQPLVLKGRQAGMYIILAMQRPDAEYFPSGVRDNLTFRISVGRLSPIGYL
                     MTFGEDFKNKPFYNKDQPGRGYAFPGFDVPVEFFAPFVYKDYHFIKEFEKFTEMIVYD
                     FTVKEDSQDQTMGDDNQLLQEQLERQMYLAKDPKGTSFSDAHIL"
     gene            complement(29988..30440)
                     /locus_tag="J8S10_001022"
     CDS             complement(29988..30440)
                     /locus_tag="J8S10_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629620.1"
                     /translation="MGLKFPNNYDITEALDETCLGAVRFGALEESDRVFDNETGDYTG
                     EIRSQRAQLVFGNPDEPKIARRVKFPADVDLTGFKRRDPVKLIDPEYHVVYIPAQDGN
                     REYSDLVIYAKGLEKVEAPTNNPNMKQSQEKGLDQKQPSVDSKEKEKK"
     gene            complement(30442..30807)
                     /locus_tag="J8S10_001023"
     CDS             complement(30442..30807)
                     /locus_tag="J8S10_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629621.1"
                     /translation="MAEKALRMKKEFLGQVFLLGSREPNPPKEINGVSGRYVQLQAEC
                     SREEQPAFFVYLTAEEDKRLRLPEKEVRISFEEAYFVFRKERVNSRETNDMGQTERRT
                     TGYQDVGVFLTGVKIGEVL"
     gene            complement(30906..35189)
                     /locus_tag="J8S10_001024"
     CDS             complement(30906..35189)
                     /locus_tag="J8S10_001024"
                     /inference="COORDINATES: protein
                     motif:HMM:NF019941.1,HMM:NF037291.1,HMM:NF037639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HAZ9629622.1"
                     /translation="MYAKTKMNWLKALALVAFSQFCFLVGTAQAHAEETTAIQPTMEA
                     IAQVASEVTEVQPAEAGVPAGEATVEQAPVTEAPTVNSKTTLDQTIGETQHPGNSPGT
                     SQPVEETASITTPASETSTLEGEKAAEATPSVQPESSEKQAEEKKRIEETVEQPAATA
                     DKEGKNEENVEKTISSTAASQNQPTKPNKESTASIENQKKKEQNIPKTGTPTLLVTVP
                     TNRSVRVRRATNAAVLGGRKIDWGENIGVTSSPNNLNFTLNYMVRFEINGQVAFCIEP
                     GVSAAEGQVYTATALKNYLKNSNVRKKTSLISYLGYVTNKDKSDEQYIAAQFMIWEAL
                     GTKIPIKNIRVDYDRRKAEIQRLINNFGEKATFNNQTHTVKIGETLKVKNKNDFLKYV
                     KDIQKPKGVNVSIHGNEVWITVTKEAPDKAKIQLNKIKVQGAPLAYRRPGAQTIGVLH
                     PTEPNASVINLQILKQGNIRVFKEDAETGVKAQGAASLENAVYGLYQADGKKIKEITL
                     KKINGKVQAEIKDLDPGKYVLKEIKAPKGYVLSDEAIEIVVEPGKTVNATAKDQVIKG
                     TIDLVKVANKDLVDSTNPDNKPKLAGIEITLTSKTTGKVVKTVVTDNDGYATFGKNTV
                     VFDTYILSETKGKEGYKLFEPLEVTISENGQTFHYVLEDKVIEQRLKVVKVDQETGKV
                     IPLANTEFKIFDTLANRYVTMEIPNDTETTDIFKTNEKGFFLTNGTLTYGKDRYRLEE
                     IKAPVNYVLNQNPLVFSITNDTEPIKVIHFANRQARKSVKLFKYEEWNKKKTPLAGVN
                     FTLYNGKNQAIGEYTTDQNGEILVKGLVADDYYFLENAPLESFQPNTDKQAFTVAFKQ
                     NAPDDGETLVVSVRNYLIPPKLETQASNKADGEKVVDPLETIVIKDSVSYTNLFVGKE
                     YTISGVLMNKATNAPILQDGKEITSTLAFIADKVNGTKDLEFVVNASVLKGQTIVVFE
                     KLFRDGIEVAAHADINDEAQSVKVNNPTVHTTAVFEDGLTVADPTGLFTLNDTVEITE
                     ILPGKAYLVKGILMDKATGEPLLVHGNTVETSVGFIAKAENETVIVPFTFDLTGINGR
                     EIVVFESLFRNDEELANHKDINDKGQTVRVTNPSVRTTATHKPTGLKEVNPLTKVTIT
                     DAVKYHDLVVGKTYTVNGVLMDKVTEKPVLVDGKEVTSTLTFVAETTDGTVNLDFILD
                     ARALRGKEVVVFEDLFREGVLLASHADITDNDQTIKISNPTITTKATNKNGGKEILAL
                     PNQTVLEWVKVDGLAIGQIYRLIVQGYLTPDGTPFEGTHAEKVFAADKEMMEFLFEFL
                     VDGRNLAGKGLSFAEWLQAKTEDEKETFEEVAKHNVDLTNKDQTVQIVEAPKPPQPVK
                     PEQRVKPATVVPMLPKTGEQTSSILMVLGLVVLVIALGITLYKVRKAKD"
     gene            complement(35336..35575)
                     /locus_tag="J8S10_001025"
     CDS             complement(35336..35575)
                     /locus_tag="J8S10_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629623.1"
                     /translation="MIDISLPEDLKPDPVTIGNSVMIFDSLDEAMSYGWKEIKDEGSN
                     WYGMRFGDGEVAKKAGIPIGKWTVDFHEAGSFFVL"
     gene            complement(35665..35937)
                     /locus_tag="J8S10_001026"
     CDS             complement(35665..35937)
                     /locus_tag="J8S10_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629624.1"
                     /translation="MSDGFEQVSIIKNQVREILRKKGYLVDSYFEGDYETWVGVYARP
                     ENKPTYLDPTTSEDAYLQNRYRVDGFKQDFAEWFEWEIENGEVKEE"
     gene            complement(36020..36271)
                     /locus_tag="J8S10_001027"
     CDS             complement(36020..36271)
                     /locus_tag="J8S10_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629625.1"
                     /translation="MRKVLVFNTRGQSFLGIEGTRVTVDGWCDCFEVGKHVELMAFTE
                     LKDKNNVEFFESDIGWDDHEEVYGKFILRKGNSYTNGEA"
     gene            complement(37267..38178)
                     /locus_tag="J8S10_001028"
     CDS             complement(37267..38178)
                     /locus_tag="J8S10_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAZ9629626.1"
                     /translation="MVDNSSGRVLKSLRKEKKLSQKKLADLAGISQSTLVKYEKASRK
                     IPKDVDNTLSKILNIETLIKDEEDKIEILIGKLIAYRDMNKLLNKELADNIGISEVLL
                     SYVLNRKRNPSKEMQKKIDIFLLSNEKEILKEINRDSEIFSLSKDDKIVMGKRIREVR
                     KNREETLEKFGKNFTIYTGKNVISRWEKGINIPDIEKLMNIAYLGKVTVPYLMYGEDY
                     KNILPKDERVSDFKKINSFSMGLRMRKIRKDYYLEREEFGKLFSPSISKWSIDRYENG
                     RDIPNTNRIIQYAYIGNLSLEFLIYGI"
     gene            complement(38374..40209)
                     /gene="lepA"
                     /locus_tag="J8S10_001029"
     CDS             complement(38374..40209)
                     /gene="lepA"
                     /locus_tag="J8S10_001029"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HAZ9629627.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEQDSVK"
     gene            40356..41576
                     /locus_tag="J8S10_001030"
     CDS             40356..41576
                     /locus_tag="J8S10_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAZ9629628.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            41596..42090
                     /locus_tag="J8S10_001031"
     CDS             41596..42090
                     /locus_tag="J8S10_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HAZ9629629.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            42083..42754
                     /locus_tag="J8S10_001032"
     CDS             42083..42754
                     /locus_tag="J8S10_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629630.1"
                     /translation="MIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGITFIVES
                     LLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWDKILHA
                     VSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLCDQFLG
                     MNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFESYKLE
                     KVKNT"
     gene            complement(42905..45514)
                     /gene="clpB"
                     /locus_tag="J8S10_001033"
     CDS             complement(42905..45514)
                     /gene="clpB"
                     /locus_tag="J8S10_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HAZ9629631.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
BASE COUNT        13805 a         9486 c         6708 g        15762 t
ORIGIN      
        1 aaaaaactag aaaaaaaaca taaaaatatt tatcattctt taaacagaaa atctttctat
       61 aaaaaacaaa aaaaaacgat taggctaggc taatcgtttt ttgaacattc ttaaaaaatc
      121 caaattattt tttataactg aaattgggta ttgatgacca tcgtttctgt agatagtaag
      181 caatcatttt aggttttcta tctctagtaa agattccttt cttatttcct tgcactctta
      241 aaatcccttg acttgttgca aaatctgcaa aattccacac ttgttcacca acaaaatttt
      301 cacatgtatc tattacttcg tgatttgctt cgtaataagc cacttgatac tcttctgtaa
      361 acattgttgg tactgtatca tgaaatccag ctactgtatc tgctccatat tctgtaaaca
      421 ttattggcgt atcaggacat ctttccatcc atccatctag ctcttttttc aacagatatt
      481 ttgcatgtgc cagatcccct cccgaaacat accaaccata ataacgattt aaacataaaa
      541 catcgacaat atctcctacc ttacaaacat ctggcgttga ttttagataa gtaacgattg
      601 ttacaggtct tttctgcgga tcaagttctt tagttaattc aactaaaggt tcaaaatatt
      661 ctttagcacc ttcggaatcc gaatctggtt catttgcaat agaccacatt acaacacttg
      721 ggtggttctt gtcgcgttct atcaattcct tgatcaccgt tttatgagaa ttttctgttc
      781 gtatctcttt ccacgtatta tgtttttcca cattatcatc taataaagtg gccatgaaat
      841 ttaaatgtaa ccctactgca ggtacttcat caataactac aataccttct cgatctgcta
      901 atcgcataat ttcttctgag taaggataat gtgatgttct aaaagaatta gcacctatcc
      961 atttcattaa attaaaatct ttaatattta cagcctcatt caaaccacgt ccattaacat
     1021 acgaatcctc atgcttacca aatcctttaa aataaaaagg tttattatta atcaaaaatt
     1081 tgccattggt aacctgaaca ctgcgaatac caaattcttc tgtataggta tcgatcactt
     1141 tattatcatc aattaaacta attttcatac tatataaata agcgtctaga ggttcccaaa
     1201 aaattggatt cttaagctga atcattcctt tctttccttc agcttcagct acaagttgag
     1261 cctcttcgtc atatatcgct attaagattt ttccggtcca ttctgtatcg atattgaatt
     1321 ctacacttgc atccaaatca gttattcttg tattaatagt aatatcactt atatagtctt
     1381 tcggagttgt atataactta acaggtctat gaatacctgc ataattgaag aaatcaaaat
     1441 taactaagtt ttcctttttt atatccccat tttcctgtac tgtttccttc ataatcccca
     1501 caggtaaagt actatcgtca ataatattgt ttacagcaac tgtaattcga ttattcccgt
     1561 cttttacaaa ccgattaatt tcagactcaa atggtgtaaa cccacctttg tgttgagtaa
     1621 taaactttcc attcaaaaaa acttttgctt catgtgttgc agatccaaaa cgaagaacta
     1681 atctttcttc taataatctt ttaggaagag tcacttcttt ttcataccac acccatccaa
     1741 catgatttct aatgttctct gtttcaaata aatcattata agaagaggga actgaaatcg
     1801 gataactctc tttttcattt attggttcta aagcaagttc ttcctgtaag tcatcatttg
     1861 tatctaattt aaatctccag agaccgctta agtcaattac ttgcctcgtc tctgtcataa
     1921 tgggatacaa catataaacc actcctatct aaatattaaa taaatgtatc ctttaaacca
     1981 caataagcat ctattggact tactccctta aattcagaaa gacccattag tttgtccacc
     2041 aatatttcta aagtttcttg ttttccatca taagtattaa tataagtctt tacttgaggt
     2101 acatcagcca aatgaaacgg acactgtaca gatacaaaaa ttgttggaat ttcatgaatg
     2161 taaaacggta tatccggagt tcctttactt gctggccaga caattcgttg aactgtgcct
     2221 ggattaacat tagctatatt aatgatcaag tcatattttt tagttaaatt tttaattggt
     2281 ctcttagcag catatattcc agctatattt ttaatttttt cttcttgcga taatcctttc
     2341 aattcttctt caggtgaaat gtatttttca acttcaaatc cttttgctga caaaatctgt
     2401 ttcaataaat caatggcttg aggtctattt ccagcaacta cttcaccaaa cccacctttt
     2461 accccatgta catctactag taaaatcctt ttatattttt ctggtacaat aggccaaata
     2521 tcttgtttat ctttaactaa tgtaattgct tggtcagcca cctctttaaa aattgattta
     2581 ttttcaatta aaccaatttt ttccagagct tcttgcttag gtaataaaat ttgttctttt
     2641 gcttttttgt gtaatcccaa tttagctttt aaccctaaaa ttctttttaa ggcatctaat
     2701 aaccgatcat cagtgataat tcctttacga tagccttcca tcatataatt aaagtcttca
     2761 tctggatcat taaaaaatag aaatagatca catccagctg caatagaagt gggcaataat
     2821 tctgatcgtt tcattgcccc agtcattcct aacatatgac tagcatcagt aactactaat
     2881 ccattaaatc cgagttttcc tctaagtaag tcagtgatta attcttttga taaagttgca
     2941 ggaagtaaat cttcatcttt cagatcagga ttaaaatgtt ttgaataagc tggcatatgg
     3001 atatgacctg ccataattga aggtaatcca gcttctatta agcctgagta tacttttcca
     3061 aaagaattat cccattcttc cgtacctaaa ctattaatac taaaagatag atgctgatct
     3121 cgttcgtcaa taccgtcacc agggaaatgt ttagctgcag gcaaaattcc actctcctga
     3181 atacctttca tataagctaa actaagttct aaaactttat cagggttttg tccaaaagat
     3241 cgactagaaa tgataggatt tctccaattt ctattaatat ctacaatagg agcaaaactc
     3301 cagttacatc caatagccga tgcttcaatc ccagaaactc tccctaattc ataagcatat
     3361 ttcgcatcat ttgttgcacc aatttttact tctacaccaa cttcagtacc atctgtacaa
     3421 gctccgttac cacctgcttc cgtattagca gcaattaata gaggaatttt actttctgtt
     3481 tgtaagatat agttttgatc atatacctca tcagcagttc ctggattata tcgtacagct
     3541 ccaatatggt actgattgac catattactc aagtaatttt tatcacgact agatcccata
     3601 ttaacaaaca attgacctat tttttcttcc aaagtcatag aatcaatcgt ctcttcaatc
     3661 caagaaatag catcttcatc taaattatat ggtttttttc gtaaatctac ttttatagtc
     3721 attttctttc tcctctactt attagtaaga tttttccaaa aagtatctat atatttttgt
     3781 tcaatatcta cataatctcc cgataaacat ttaaataaaa catcagttct taagttttcc
     3841 catgattctt tttctttatt gaccaaaata ggataaaaga aaactttatt tttatttgca
     3901 gcttctagat caccaggaga atcaccaatc attaatatct tatccaaatc acaaccattt
     3961 tcaattacac ttcgaataat atcttctttt tttcctttat cttgacaaca cagttcatca
     4021 actaatgata ataattcatg tctttcccat tcttcttgaa cagcttcctt attagctgag
     4081 cttacaataa ttatcttccc atattttttc agagctttta tagtatctct agcacttaaa
     4141 aagggtttat ctaatccttt tgcttgacta atctgttgat tgacttcttc cgaccatttt
     4201 aaagctttta ataaatcctc tgactgagaa tattctattt ccctcttcaa agatggatta
     4261 gacaattctt ttgttagaga tacccagtgc tttaatcgat taatcgatgt tacatcattt
     4321 ttttctaatg ttttaactaa acctaaaaat ctgtttattc cacgagtctc tgaatataaa
     4381 ttaatattat tccaatcctg taggaatttt tctctatgat gaacatcaaa aatctctgca
     4441 gcaattggtc cgaaaaagag attgtgttta taagtcatcg tatccataac acagccatct
     4501 gaatcaatac aaaatatcca attattcata tttctctcct atttatgttt ttgttttaaa
     4561 agctcgcaat tttctaagac tttatcttta gataatggat aaaggaaaaa taaaattaat
     4621 cctacaatca gaaaacaaat tgatggaatt aatgttgaag cgttatataa cttttctaaa
     4681 acatctcccg tttgtacatt tgctaaagag tcatagccta taatagaaag agtccaacct
     4741 ccgacgcctc cagctagagc ttgacctatt tttctagcaa aagaatatac cgcatatacg
     4801 gtcccatctt ctctttgatc agactttact tcttgatcat caataacatc agtaatattt
     4861 gcccaaataa cagtattaaa cacacccaaa cccatatagc caaccgaact aagaattaag
     4921 aatacataca tattactagc ttttatcaaa aataagatca aatatactat tgctgaaaag
     4981 aacattccta ctgatgccag ttcttttttt ccatattttt tacttaaaaa caaagttaaa
     5041 ggcgaaacaa ctattaaaac caaaatagga ttgataaaat tcattaaaac tattccctgt
     5101 gcatcattat agtaatcagg aaatacataa ttattcatac tcataattaa taattgagca
     5161 aggagtaaga aaatagccgc accaattata gaaagtaatg ccctattttt aactaaccct
     5221 tttaaagatt ttaacaatga aactttgtat tgagattggt caattcttac tcgttcagta
     5281 gttagtttat aacatattaa ataacaaata agtgcacata tcgaaaatat tcccgcaaca
     5341 attgtaaaag ttgatccacc acgaactatt tgagcgcctg aatcatctct tgtataaata
     5401 aataatggtg ttaatacacc aatgaccaaa cttgctaaag cagctccaac atttcggaat
     5461 gtcgatagca ttgttctttc ttctgtaata gaagtaatag ctgatgccat tgatccataa
     5521 ggaatattta tagatgtgta aaaaatactc ccccataata tatacgtaac atacatgtat
     5581 actaccttaa cgctcataga agctgaaatc atagaagttt gatacattaa aaaacttgct
     5641 aaagcgactg gaccactcat tcttaaaatc cacggtttaa acttaccctg cttagttgct
     5701 ttcgatctat caacaatacg ccccatagtt acatcagtaa ctgcatcgat aaatcttgct
     5761 actaaaaata atgttccaac ggcagctccg cttatcccca atacttttgt ataaaagatc
     5821 attaaaaaag aactagcaaa aatgaaagta aaatcgtttc caaaatctcc aaacatatat
     5881 cctattttgt ctcttatacc aaattttctt tccatacaat tctctccctt ctgttgttaa
     5941 gcgttttcat tctgatgaaa gtacgtacta tactctgaag cgtaaagagt cagtatttat
     6001 tttttacatt tcagagtatt atttgttttt tctcctaata attctttatc tcataaaact
     6061 tatctatata tttactagct actcgactta cttcttcaaa atcacctttt tcaacagaag
     6121 ccaataaatt cccacctaca ccaactgcaa caactcctac ttcaaaccaa tcttctaagt
     6181 tctctatact tactccgcca gtaggcatta tatttacgtg tggtaatgga gcttgatagg
     6241 cttttacaat ggatggacca aaagcagaac ctgggaatag tttaatgata tctacgccag
     6301 cagtaagtgc ctcctttatc tcagtaattg tcatacaacc tggtaaataa ggaatttgat
     6361 ataaattaca aatctcagct gtttgtcgat caaaagatgg actaacgata tattctgccc
     6421 cagccataat tgcgatacga gcagtaaacg catctaaaac cgtaccggct ccgattatta
     6481 catctttttg atcagcatat tttttagcaa tttctttgat tatttcttca gcattaggaa
     6541 ctgtaaaagt tagttcaatc cctttaattc cacccgcaat aattgaattt attgctttaa
     6601 tggcctcatc cttatttttc ccacgtacaa ccgcaatgac tccagccgct tctaacttac
     6661 ttaaaatttc tacttttttc atatctatct ccttccttta tggatacata ctttgtctag
     6721 ctgtactaac ttacaaagaa taaatttaag cttttatttc aagtattatt ttctacttcc
     6781 gatttcaaaa aaattaaaat aattatacgc attacgataa caaatattct ccactatctg
     6841 actaagatac atttcatcat ctggaattcg gcctgcttta acccactcgc ttagtaattg
     6901 acataatact cgacgaaaat actcatggcg aggatagctt agaaaacttc gagaatcagt
     6961 caacatacct gtaaaattcg acaacaaact ttgttgtgcc atcgtagtca actgttgacg
     7021 cattccttca gctgtatcat tgaaccacca agcacatccc aattggattt tttgaatcat
     7081 acccccttgg aagctttgca ttgctgttgc tagtggaagc caatcagttg gatttaatga
     7141 atataaaatt gtttttggta agcacccact cttttcagcg gtatcgaaca atgctacaac
     7201 attttgtgtc aaactagctt gatcccccat cgaatcacca ccgacatcta ctccaatttg
     7261 ttcctttaat atacttgaat tatttcttaa agcatttaaa tgcatttgca tcgtccaacc
     7321 atatcttgta tactcagaca tcaaatgtaa ttgaatacct gtaacaaatt gtgcaatttc
     7381 tgataaatgg aaatccgttt ttcctgctaa agcttttatt aacagattgt cgagtatttt
     7441 ttcatctgct atttcataaa aataagtatt caaaccgtga tctgctaatc gacagccaat
     7501 ttgatgaaaa tgatccactc gttggctcaa tgcttgcttc aacccattaa agtctttgat
     7561 tggtatagcc gctgtttgac taagttttaa aatatagttc gaaaagcctg atgatttgat
     7621 actccagacc ttatctggac ggaaagtagg taataccttg aaagaattat cctgtttaga
     7681 aagctcagta tgataccaca agtcatctgt aggatcatcc gttgtacaga tggctttcac
     7741 atccatcatc tccaacaatt ctttcgggcg ataggaatcc gtttgaattt tttcgttagc
     7801 acgtcgccaa atttctggtg cattcttctc agaaattgtc aaatcaatat caaagtaacg
     7861 ttgtaattcc aaatgagacc attcaaaaat aggattacct ggcgccttct ccactgtttt
     7921 tacaaaagct aaaaattttt cataatcatc acctggacca ctgatcaact cttcttctat
     7981 accattagct cgcatcaatc gccatttata atgatctcca gctcctttat catttaacca
     8041 tacctgagtc aaattcttgt attgcttatt ttctagcaaa tatgctgggt ctaaatgaca
     8101 atgatagtcg ataattggtt ggtgttttgc aaatttatga aaaagtcttt tagctatttc
     8161 attctctaat aaaaagttct tatctaaaaa catatttaaa cactcctttc cttccgttag
     8221 tttttagaag agaaaatttt tcctctaaat aaactccctt atataattat ttactcgccc
     8281 ccttttcaag cgcttcccaa ataccattta aataaactgc acctagagct cggtcatata
     8341 atccataacc aggtctaccg gtttctcccc aaatcatccg accatgatct ggacgaatat
     8401 agccattaaa tccattatcg tacattgttt ttaatatctt atacatatct agagaaccat
     8461 attctgattt atgcggcgct tcgtaaaaat cgagtccatt gtcacttaaa tatttgatat
     8521 tacgaacatg tgcaaaagga atccgatccc gttgacaaaa ttcagataga atttcataga
     8581 catcattatc tggtcgttct gcaatacttc cagtacataa tgtaatacca ttagaaggag
     8641 aatccactac attacacaac caatctaaat cgtcacgatt tttaacaata cgaggtaatc
     8701 cgaaaatgga atatggtgga tcatctgggt gaactgccat tttaatccca acttcttcac
     8761 atgtcgggat aattgctttg agaaaatatg caaagttctc tcgtaatttc tcttcatcaa
     8821 cttctttata ggcttctaat aattgcttaa tttgtgataa ccgatgaggt tcccaacccg
     8881 gcaattcaaa attattagta gaattttcta cttctctaat aatttcctcc ggatcagtag
     8941 ggatattttt tgaaatatag gctaacgtag aagacccatc atctaaacga taatccaaat
     9001 ccgattttac ccaatcaaat actggcataa aattataaca gataacctca atcccaaatt
     9061 ctgccaaatt gcgaatcgtc tgtttataat tctcaatgta ttgatctcgt gttggtaaac
     9121 caattttgat atcatcatga acattaacac tctcaataac tttcaaggta agtccattgg
     9181 cttcgacttc atcttttaaa gatttaattc gttctctcgg ccaaacctct ccggctggta
     9241 tatccattaa tgttccaaca attcctttca ttgctgggat ctgacgaatt tcttgtagtg
     9301 agattttttc ttcatttgcc ccataccatc taaaagtcat ttccatagtt actttcctcc
     9361 aacttctgtt atatatttat tgattgtttt acgaactgct tgaggaccta ctagcatttc
     9421 gcaaaagatt ttttcagttt tctttcctac cccaacttga tataaatcta aaccaaagat
     9481 ttctttattt tctaaaattt cctgtaccgc acaatgaatc tttgaaggat cttgttcacc
     9541 taatttcaat actgataatt tatcctgcaa ctctaccaat aacggatcag gacttggcac
     9601 aaaattttcc ccttgatcat cgactgccag taaataacgt aaccaagcag caatagcgat
     9661 aggaataaat gttagatttt ctgcatttcc gtctttttcg acatactttt taattgtttc
     9721 accatagcga atcgctactt tttgagaagt atctgttgca attcgttgtg gtgtatctgg
     9781 aatataggga ttaggcaaac gtttattaat tacttcatca ataaattgtt ttggatcaat
     9841 aatgcctgga ttttcaacta ctggtaaacc ttctaaataa cctattcctt tgattaaacc
     9901 aaccaaatca tcatcctgca tctctgctga aattgattga tatcctagca gacaacctgt
     9961 tactgccaaa gcagtatgaa gtggattcaa gcttgtcgta accttcatga tgtctgcttt
    10021 atcaaccgtc tctctatctg tcataatcac accagccttt tccaatttag gccggccatt
    10081 tggaaaacta tcttcaataa ctaaataatg aactacctca gtattagtga aagcagcaat
    10141 attggtatgt ttttttgtgt gaatgatatc taaatcctcg agccccatca tcaatagatc
    10201 ttcctttaca ttctctgaag gatttggcgt aattcgatca atcatactcc aaggaaaagt
    10261 cactttttct ttatccttta aataagcaat aaatttttca gaaacatatc cttctttttg
    10321 ccaagcttct gcaatcgtaa aaatactatc ttgaaaacgt tgaccattct gtgagaaatt
    10381 atcagtagaa accatcgcaa tcggcaactc tccagcatta aatctgctat ataacaagga
    10441 tgttacaata ctcatcgtat gttgaggatt gctaggtcca gatttgatat cagctttgac
    10501 taccgaaaag aattgccctt tagaatcttt taaactgtaa cctttttcag taatagtaaa
    10561 cgttgtaaac tgtaatttag gatcttcaaa atatttaacc actctttgat agtccgctat
    10621 attcttcgga ttgcaatata aactatcagc cgttactgcc aaaagtcttt ttttgagttc
    10681 accatctcca ctcataacaa tttccaaaat gtcattgtta tagtcatgat aagctttttc
    10741 cactacttct tcatcaaatg tttcacacac aactactcct gtttctaatt cattttgatc
    10801 tgctaagcat tgagcaattt ctgcatgaaa tcctcgataa agatttcctc caccaaaatg
    10861 aagccatact ggatgttgct ggccttcttg cttaacttct ttgacatcaa aacacggcag
    10921 tagaatctgc atttcattga attcttcgat agaattttgc caatttttaa tcgaaaccat
    10981 aattaacctc ctcaaactga tatgttagtt ttgatacatt ttatatttta aaacccattg
    11041 taaccgttgt caatataaaa agggaataaa cttgcttttt tctaccatat cagaatgatt
    11101 gtatttttta ttcagaaaaa taaaatactc cttctttttg gactgatttt atcgaaactt
    11161 attttttctt tttttcatgt attcttttat ttttataact agtgtattac ttcaaaattt
    11221 gatattatat ggcatgaaca gaattaaaat atcagttaaa ataaaagtta aggagcattg
    11281 tgtatgacaa ttaaaactag tctccaaaat caagcttacc aatctattcg ccgacaaatt
    11341 atctatgctg acttagaacc tggaaaaaaa gtatcagaaa aaaaattaga agaaacactt
    11401 tctattggtc gtacaccaat acgtgaagca ctgattcaac tccgacaaca aggtcttgtt
    11461 gatacaattc ctcaaagcgg aaattatatc tcattaattg atttagattc ggccaaaaat
    11521 gctcgatttg tcagagaaca tttggaacga caaattatgt tagagtgttg tgccaaaatg
    11581 aataaccaaa aaaaacggat tttagaaact ataatttcag aacaagaaaa agctgttagt
    11641 caaaaaaatg ctcgtagttt ttttcataat gataatttat tccataaagc ttgttttgaa
    11701 attgcagagc gagaagaagt atggcaatgg ttagaaaata acaatacaca cttagaacga
    11761 tttcgatggc tacgagtaaa aacggaagga ttaaagtggg aaaaaattat ggaacaacat
    11821 tatcaactat ttgaggcatt aacaaaacaa gatccagaag aagctaactt tctaacatcg
    11881 ttgcatcttc atttaatgct taatgagcaa aatattgttt tagctactca tccaaaatat
    11941 ttcaaaaata tataactttt aactcttttt aaattaaatg gttgttctga tcagaaaaat
    12001 atcgcttgtt ttcttattat gtaatatatt tcataaacta ttctgcataa caactattgt
    12061 ttgtactttt tacattggat aactaattat gactgctgat aacttttgat attaaactag
    12121 tatctccaat acaaataaaa aatagatatc ttgttcatca aaattagttc gtggatactt
    12181 accttcattt acatcattca gcggtttccc attttctttt attctattat ttcattttct
    12241 aatagacttg gcttcatttc gcaatacttt ttttcaatag gcatcaaatt ggtgttgttt
    12301 agatatttag ttgtagtttt gtgacatgat aagtatgctc ctttttctct tttccactaa
    12361 tacaacgatc aaagggtgct tttttcaaaa aactagaaaa atcaaaataa gattcgtatt
    12421 ttgattctat atatcctgtt tcaactacat cttatatttc acaatagaat aaatagcctt
    12481 ttgcatagct gcttaactta taagaaattg caatttactt cttcaaagtg aaaacgaata
    12541 tgagtaaaat aaaattattc ttcttacaga taattaaaaa tagcgcgtaa caaaaatcgg
    12601 cattcaatca cataattagg attgatgccg attacttata ttctacgtat agttttagta
    12661 ttcttatttt ttatcaccag taaccaattg agaacagccc taaagcagaa tagtctttta
    12721 tctcaaaacg cttaatttca ggcttaggaa tatgaataat cttttgagta tattctttct
    12781 cttttaatct tactgaagaa ataccactgc ctatcttttt tacaaatatt tcatttggtg
    12841 tacagactaa taaaacaata tttgtaatca atccttgcac taaagaatta aaaggaagac
    12901 tatttaaaac agggtgtgca taactataac atgtgaagta gttattttga actttaactt
    12961 ttaaaaactt taaaaataat cttatttgtt cttctaaaca atcatctata ctcatataat
    13021 cactccacta attaatctcc ccaaaaagac acagcattaa gagatatacc aacacaacag
    13081 tgcaaataac tctacatctt ccttcgcaac cttatttcaa taaaccataa aaattatttt
    13141 ttaatagaaa ctgaaaatta aaactagaaa aagtagtttt accgaatgta agagcatcat
    13201 caccatcaat atagaaatac attcttttcc agttacattt aatttttaaa caaaattctc
    13261 cccaaaaagg aactttttct agtgaaaact tggtaatctc tttgtaatta attcttgtta
    13321 aagaataatt aaacacttca tttttacttg ttattttttc attgactata actagttcat
    13381 ctggtaaaaa aattaaccaa caaacatcga caaacagtaa atgatataat ccatttccac
    13441 ctccaagcat attcaatact ggtgaacatg ccttagaaac acgaatatag ttatggttta
    13501 aatagatatt ttctttaaac attgcttgtt taaaagccat atgctcttgt tctaaacttt
    13561 tcataaactt ttactctaat gcacagctag cagcagctgc tgcaattcct gctacaatat
    13621 ttaccttagc taactcttta gctgcagctt ttcctaattg tttttctgca atttttaata
    13681 ataaatccgc agctttttca aaattaaaag cttttaatgc ttcaataaaa tctccctgcg
    13741 tacctatagc ccaagccact cctcctccag gaagagaatt aatggctaca catccagcat
    13801 atcgtttcca atcaactttc tccattctag gaacaataat atgttcataa aagactcttg
    13861 ctgctcttcc ttgttcgtta tcttgactga ttcgttcacg aatagcacca aaatccttta
    13921 tatggtatac accatgttcg tctaaaaaac caactgtatc aaaataaaaa gttaattcat
    13981 ctactaattt attctttatt tctaaatcaa ctgtattcac tttttctgtg gcatacacac
    14041 ttgttccagt actaacaaaa gtacttaaac ctaataagaa aacacctaaa acaccaaata
    14101 ttttaattat tcttttcata atttctcctc cataaaaaat aagttacttt ttaaatatct
    14161 tgtttatgaa ttcattcccc aaaggccttt taagattgat acagcagtcc gttcacttct
    14221 tttagacttg tcatacaagt cttttaaatg atcccatatc agactagttt gtctatctag
    14281 cttcaatcca ttaaacgcta atgaacggtt cattttttct attactttag ataaagctac
    14341 agaaattttt ataccttcac aacgcgcatc ttggatttca ataatagtat catcaattag
    14401 tttttgaatt tcttgcctat caacatattc aatcttagaa agagaatctt ttaaagctac
    14461 taatgattca acgatttctt ttttctcttc agacattttc ttcctccttc tagtgacccg
    14521 taaagccatg tagagcagag tccattgaac cagtaattac actatctaca acgccattcc
    14581 aatttactct acattttcca tttttcagat ttgtcggtcc atacggatag cctttttgac
    14641 attcaatgtt cggattatac cagataggat tataccattc agccgcagaa gcagattcag
    14701 tcgatacaaa caatcccaca ccaacaaatc caatacacat cacactatag ccaattagtt
    14761 ttttcatctc gtatccatct cctaaaaaat agaatagttc ttatagttat tcataagaca
    14821 tattttttcc gtttttgttt tatcctttct gtcctataac aacttttttc aagtaaagaa
    14881 tgacatagtt tttcttaaaa aaacagtctg tttttttcta tttcttcggt gtataataaa
    14941 tatgagtgtt cattttttat tttaatacgc actccgtaca taataaatct tgatcgcatc
    15001 aatcttttga gcttcttgat ctactttcaa ttgaagtaat acaaattgag taaccttatt
    15061 cattgtttct tctccaaata acaaatattg atccggattc tctatatctt gtgtcacctg
    15121 gtaaagtttc ccagttgttt tcatttgtac atgcgggtct acatcaatac tattgtcttt
    15181 aatacaacga tctgtcatat agtccctcac agcttgattg cgtttataaa catctgtgaa
    15241 attactccat tttctagcaa aatcttttaa gaaatttttt gtcatttcat ctatttgcat
    15301 ttgttgcgct gtctcgtctt ctaatgaacc aatttgactg ttactttcag tactttgaag
    15361 agttccactt gtttctttta ctgcttcgat tgtttcttct gtcgttctca attgtgtttt
    15421 ttgtttttca gaagaaaacc aatgacaacc agtaagacct atcaaacata accaactaaa
    15481 tactaaaatt atcccttttt tcacgtttct agtcactgcc tttcttattt caccttacga
    15541 accagactac gaatttttgt ttgattgtac gtgcgttgat accgagccat aatccgtcct
    15601 tgctcggcat tctgttccac actagagaaa tgttgtccgc catatgaaac atctgttata
    15661 attccggtgt gaccatagat tccaggagac aatgcaccac ctgcttgcca attcaccaca
    15721 tctcctgctt gtaaatcact tggttttggg ttcatgatta cttgccaacc ataggttgtc
    15781 cagttataat cttcccctat taacatcgca aacatgtgtc cagaacccat taactgtggg
    15841 ccacctaatt gagatacata ccatgccgta ccaccataac attccccatt atttacggat
    15901 cgtccaatga tccgatccaa aaccttcgca ttgcctttac tttttcctgc aataagcgaa
    15961 gttttttttg ttggtaggct attccaatgc ttgatcgcaa aagtatcata ttccgttaag
    16021 ttataggacg ttatgatact cattgctcct cgataatacg gactcccttc ggtaatacct
    16081 gctgccgcat agcctccacg acctagaatc aataaacaac ttccaggatc tttattgccc
    16141 acacattgat taaagttgct ttggctcgcc accataaagc cataatagtc ataacaagct
    16201 tttaagttcg gaaacttcat atagaaacca ccttcagaac caccaattcc acgtgcagaa
    16261 ccttgtgggt agggacaacc aggaaaccag gtaatcccaa aaaagttcgt atcgtttctt
    16321 ccagattgtg actgtccata agctgattca tagcctaatt gagaaagaat cacactcggt
    16381 aataactgat actttacagc tgcaccaact gctgcttgcg catgttcatc tgtgattgga
    16441 ccacgtcctt taatctctga aaaaatcggt aatccttcgg tatattcccc attaaaagcg
    16501 acagctagac ctgtagcttc tcctccatgc tcagaaagtt ctcctgaaaa aaagaatggc
    16561 aatagaaaaa agggaagaat aaagaaaaga agacaaccta gacacccttt cttcatttct
    16621 tcctcatcct ttcttcgata atggtttttg gactgttcgt ccttttggta aagtaaaatc
    16681 agttcctggt tttgcgtcca aaatcggcag tgttttagga tccttttcta ttttttccga
    16741 ttgctctgtt ggcttatcta aagaagaaaa tgcaggttgt aacgattttg gtgcggaaat
    16801 cgacggttta ctttcagacg aacgttgccc cggttgttgc acagaacgat ttcctgatag
    16861 agtggctacc gacgaattag gaacagagta ttggttcaat aactgctgca ttgctggata
    16921 actcccattt ttcgcctgat ttttcacttg gcgaatctgt tgtgaaagag aaccagcagc
    16981 tgttaattgt ggcacgggta cttttccaga aggcaacgga atcgattgac caacaaaagc
    17041 gataccttta tttaacaatg gttttctttg attattccct tgttgcttac tcaattgtgc
    17101 caatgattgt acctgttgtt ttggtcttac tgaattcatg gacgaatttg gaatcaaacc
    17161 atttgaaaga ccagaattcc actctgtttt cgatttggta gaagacattt caggctctac
    17221 cccatgataa cgaacatgac gaccactata aggcaaggct tgatttgaac gcccacctag
    17281 ttcaaaggga ttaaccactt gcctcccttt taccgattct tgtggtgtac gtttttgttg
    17341 aaacttttga aatccatgta tcgctgcaga agcgagtgga ttcgttgctc gatacacatt
    17401 ccctgctaat cctgcacctt tgattgccaa attttgtcca gcagttgata gttgaccagg
    17461 cagttgtttc atttgagaca aagaatgact tgctatgttt ttcgtgttgt ttatagtttg
    17521 atctgcagct cctaacccta gtttctttaa taaatctttc cgttttacaa tgagtaaaat
    17581 tgataggagt gctttgacaa acatatttcc taaaaaacca aaaacagtat tcattggaat
    17641 taaatcgtct actatgttat agatcaaaaa tgccaccaaa ataatcacac tgtaaaaaga
    17701 tttttgaaac atcaagccca aaaaggactt taaggtattc atgagcatat aatcaaatac
    17761 tggaacaaaa gaagcgagta atgaaaaagg aatcacaagt aataaacaca acaccaacat
    17821 ttgaaagata aaacgaatca tgccaatcac tacaagtggt aatccaatac ttagattaag
    17881 caatggcacc atagaaccaa cgactgcttt ataaacagct ttagttggtt gaatatagac
    17941 acgataagcc ttctttttcc ctctatcttc tcctgcagca gtggtcactt ttgtctcaat
    18001 atcagataat tcttcacttg acgcttcctt ggctagaaat tcttgtggtt caatctctgc
    18061 ttgatacaat tcttctaaat ttgttgtccc ataatttaac aatatatacg gatcaacaac
    18121 agccgcttta taataaagtt ggcgcacttt ttgaatggct tccttttgtg tcgttggcac
    18181 taaaacacca ttgacatctt ttgtcgccaa ttcatctaga ctatttgtag cagaaaaaat
    18241 aaagccttct acctccacgg acaaatcatt taaccctttg gtaaaagctt ctcctttact
    18301 aggtacgtta ctaccatagc caaaccaaac cattgaaaaa atgacaacga agagaaatcg
    18361 aataaacacc atttttgcgt aatgtttccc tctaaatata cgaagagtaa atagatataa
    18421 cacatacaag acgacaatcc ccgcaccaat aggatcgtat atttttgaat aaatagtatc
    18481 cgaaaaagtg aaaaactggt gaattaactc gttcattgca gctccttcat agagcttctc
    18541 aatgacaaaa tcaaggcctt gccaaatcaa tttacttaaa ctaaagaaca tattcgtcat
    18601 catttttaga aaatctgtgc catttgcccc aaataacatt ttgcctaatg aaaattcact
    18661 atcagataaa taagaagaaa aggtatcaat atgaaatttc ccaatctcat agatcgattg
    18721 atccacctgc ttttctgccg catacaccaa tccaccaaca aaaagcagtc cgaatccaat
    18781 cgttaaaaaa aacaaaacgc accatttctt ttccttatgc tttatataag ccattgtttc
    18841 acctcatttc tattgcatga ttaacgtatc ctgttcttct acttgagagt gacttgtttt
    18901 ttccgttgtt tgtaatgcag cggtcatttc ttcaaacaaa ctgtgtacat tgagttttcc
    18961 tacacgtcca tagggatcta acatccaaca ctgtccttta atcatgtggc tcatttcagc
    19021 taagttcgct tcatttactt ccaaacgtaa atgattcaaa atcttttctc gctcactgtc
    19081 ttcatcaaaa gcaaagacga caccaaaatt ccctttttct ttatctgaac ctaagtcacc
    19141 aataaattgt gtatctaaca ctaattgatt catctgggaa cgccccacac gtgccattgc
    19201 tgcaataata ctacgtcctg cgttcgaatt attaaatacc catgcttctg taaaataaat
    19261 cgctgttttc ttactactat ctcgttttcc aaacatttca caaaaacgac ctaaactaat
    19321 catcaaacac aaagactttc gatccgcatc tgtatatagt tctggtcgga cattgtcatt
    19381 tggtaatttc aaatcttgga tctctaaaat cgttgttttg gcattaaagt ctaatcccgg
    19441 gttttctcca taagaaaatc ctaaacgtaa aatcgaatct tctaccgtca agcgtaaaaa
    19501 ctcaccatat tctcgaacct ctttttgttc catttgttct aaatagtcga ccacatgcat
    19561 caagccaact tgttgtccgg cttctttttg aactaaaact tcttggattc cctttaatac
    19621 cgcccctttt aaaaggtgat tggtacctaa cggacttaac tcatcaatca tatcctgggc
    19681 tacttgtttc gcatctactc gggataaaca aacaattgga tctaatacac cataattacg
    19741 gggatttgta gcatctaacg tgacataact cattttttgc aaatgttcta caaacaaagg
    19801 gtaatgtttc tgataatacg ggtcttgaat gagtttcgta aaccatttgc gcttttctcc
    19861 tttgggatcc acaaataaac tttgtacatt cataaacgaa ctatacaaaa agagcaagcc
    19921 aactaaaaag gtcttccctt taccggtttt tccagttact gctacatgag gcgcatcaaa
    19981 caacgcacct ttgattcctt ccgcaatggc tagaagattc aaaaagacaa aacgatttga
    20041 cgcataaatt aattcttcta atggtgtttt ttctcctcga gaaccaccat cccctaatgt
    20101 atcttgccga ccaatatacc agccggattc catacctaat tctgatactg ctgaaaacaa
    20161 ccattcgcca actgcttcta cagttgttcg gtgcttccaa tgtaactgcc gtcccaatgg
    20221 ttgccctaat aaacatttat agaacaattc tcgttgatca ttttttgcac ggtggatatg
    20281 gataatcgta tgaagttgtt gaataaccgt tgcactattt tgacgaactt cttcaaccgt
    20341 ttgaccgtat acaataaaac atgcgatcca atcgacgaca ggttgcccat tatctactcg
    20401 ttgctttaaa tgttttacta atcctcgaac agttaataag cgttcactag gttcttcatc
    20461 attttgaacc aattccttat gctctgtttt gaaccgttcc gatagccaat tcagttttaa
    20521 accaatacct ccctgtcctt tcaagcgtgg atagtgaatt ttcattcgca attctgctgg
    20581 gaaagaaaga tcctgagcaa attgaaatag atcacaattt ctcatatttt caggtgtttc
    20641 cccaataggc aacaatgcta aataactact ccctaactca tcttctaatt gaagaaggcc
    20701 tttatgttcc ttcggtatac gtacatacgt tccttgattg tctttcagta cttcccaatt
    20761 attttgttct tctactttgt gagccattcc tcgaatatat tgcagacgat tgagatacaa
    20821 cagctctttt tttactaagg gacgaataga aaagctataa agtaattgtg tcacttcttt
    20881 tacataagga tcactttcag aaaacaaagt ttccaaatca tctacttcta atccaaataa
    20941 gcgtgctaaa cttcctgcta aatctaacca gattagattt attacatcat gaaaactctc
    21001 caccgttgct ttttctttga ctttgattcc taaaataaat gaaggacgat agacttgacc
    21061 ttctcgttcc aacaatgtca ctgtttcttt tgcataatac gcaccaattg cttgactatc
    21121 gggagaaaat ccctttccta atgtgtcaaa cttcgtccgt aaattcattg ttcgtggata
    21181 catcaccaac tccacatctt cataatctgc taaaagcaac agtaaacgag ccatcatttc
    21241 ttttatttcc tgtgtctttt ttggtgtgtt ttttgaaatt gttcgtggaa aaacatgata
    21301 gtaggcccag atacaatcct ctccatttaa caaacaattt ttcttgaatg cttttactgg
    21361 ttcttttaca agcaccaatg aatttcacct cccaataaaa aaggaacaac cagttgattg
    21421 tccctttttc taatcctcta aataaacata cttattcaca aaaagtaatt cttccaatgc
    21481 attgtttgat accttgtccc agttataata cacacaatca ccattcatca tacgaatcat
    21541 ataacaaaac caatcccata aataaaaatg cacttttttt ccatcaggtt ttagttttgc
    21601 cagtgctaac acacataaat aggggagtcc tatataaaaa acaactcctg ctggtggaaa
    21661 aaaagaaatg acccaaccaa taaatgaacg taaaaataaa tattcaaaga ttacgaccaa
    21721 caaaaaagtt gctgcattga ctaatgcaac tggaaatgga agacgccaat tgcttgtaat
    21781 ctgttgtacg cgataaggtt ccgcataaac aatcgaataa tcataaggtt cccaatccac
    21841 ttcactatcc tcctaatcca taaataattt ttcaatgatt ttaccaaacg catcaaatac
    21901 acgtgttgga tcatttaaga agaaataaac tgcggcacct gctgcgatag atattaatgc
    21961 atttcctact tttgatttca taaaatttcg caatcccaga taaacaacca ccattattaa
    22021 aaaatagcca ccttgcgtta atataaaatc tacaattccc ttcagtgtca tttccgttct
    22081 tctcctttcc tatccaacca attatgtgtt aatttttcaa cataatactg atttgttttt
    22141 ttcgtaatga caatcgtcat ttgttctttt tgtaaaagtg acgtatcacc atctcgaaag
    22201 acgaccgttg cttttacaat aaaaggtttt ttcgtttctt tataacgcaa tactttcatc
    22261 tctacttgat caactttagc tgtttgattg agtccttcag gttctttcat catgtatgac
    22321 atatcttttg cattgttttt cgcatactta tctaagaaat cttccacaaa tccttcaaca
    22381 tctttcgctt ccgacgcatc aaccgtttcg tataatgtgt catcataagt aatcattcgt
    22441 tgtttttctg tattctttgg tagtgccgta aaataaggat aagcaataat acgacagccc
    22501 ttgtttgaaa tagaaaaggg aagattgagt acttgtgtga ttgtcacact tgtttctttc
    22561 ttactctctg gattcatcga gcgaatatca taagttactt tataactagc agttggaatg
    22621 gtttcaattt cttttaatcc aataaacgaa gcagcagtta attttcgaac acctgaaaca
    22681 cttcctggtt cttgaataaa gttttgtgca taaaactctt tttttaatgt ttcttgacgt
    22741 tgttgttctt gttcatgatt atcgaatgta ttcatataca aagcaacaaa acgattcata
    22801 aaggattcaa tttcaggtgt gtacgttaat tctgaccgac tttgtacttc tttcttttgt
    22861 aattgttgga tttcatcttt caaaaacgac acttgaacct tcgttttcat ggattgaaaa
    22921 aatgccaagc cccctgaaaa acaaagaaat aaaaccaaac accaaatcca tttcactgct
    22981 ttttttgaat ggattttctt ttgcttcgat actttctctg tataaacttt ttctttccgc
    23041 cgtagttgtc gttttttcat aagctactcc ttctagtatg tttttactag tacgtacgat
    23101 tgacaacgat aagcttgttt ttctgaaaaa tagtccattc aattaccctc attttctatt
    23161 ccttttctct ttcttttata tccaacaaat ccagcaatac ttgtcaacac tcctcctaga
    23221 acagaaagtg caacatgtat ttcttcacca gtctttggta agacttttgt ttttccatct
    23281 gctgttttga tttcaatatt gccacttgga agtttcttta caggaatcga caaatccttt
    23341 accaaattcc cttcactatc ttggattaat ggaataccat cttttacacc aacaattgtt
    23401 tgatcacctg ctacttttaa tggggtggtt ggtgttggaa tatgggtcaa ttcctctaca
    23461 ttactagtga caatcggtac actcattcct tgagaagtat tcgtcgtaat ttcaccgctt
    23521 ggggttaccg atactgtgac ttcttttgct ggaacaatag gtttattttc ttttggaatt
    23581 gcttctgatt tttcaacagg ttgtttcggt tcttcttttt gttcttcact ggtagacgac
    23641 atcgttggct gttccgtact tgacgaatca gtattctttt cagaagaact ggttgttcct
    23701 gattgttccg gagttgtgac tatacttgaa tccgttgttg ttgaactatg cacaccttct
    23761 tcttcgatcg aatcagtcgg taaagttgat tcaggaaact ctggttctgg tgtcactggc
    23821 tctttttcag gtttctctga ctgcaattgt tcaggttctg ctggtttttc cgttgttcct
    23881 ccatttagct ctgtctcaac atctggtaat ccttcccctg gcaatgtttc tacaatttct
    23941 gacttaggtg tttctacagt ttcatctgca taaaccaatg aactccctaa ttgaaacgaa
    24001 aataatgaaa ttcctagtgt tgttacgact gctaatgttg tttttttcat gattattcct
    24061 ccaatttttt atgcaattcg tgttttgttc atagacgccg cactaatatt atctgaacga
    24121 taaaagaact cccgtccgtt ttcttctaac ccaacatatg gattattttt gaataattga
    24181 atcaatagtt cactggtgtt gtattttgga tagtttgcaa aaaaataata ctgtgcttgt
    24241 cgcccatccg aaaattcaac aagtaattca taacgatacc gcttcaatcc ttttcgttgt
    24301 tttaaaggat ctctatacca acttgtccat cgttccattc gtggatagag atagacacga
    24361 tacacataga acaatgccat accacatacc accaaaaata ataatcgcca cataaaaatt
    24421 cccccttttc ttctaccttt cttgaatcat cgaacattca taccctctat agagatttga
    24481 aaaatccatc atcaattgtt catataaacg ttgttgcaaa tagcgattgt ttcgaataca
    24541 taattcttca tagccatcaa tcacttgatc ttctttttca tagcatcttg tagctctatg
    24601 acgctcagct tgcatgacat aaccaaactc tgcaccatat cgttctactg ttaataactg
    24661 ttgactacgc aataatgcaa tataacaatc acaaaaatgt tcaaccgaca tttgattttt
    24721 ctcacgtttg tgaaataggt attctttaga aagcacatta ttcgttaaac aatctgataa
    24781 atagcgataa tctggcggtc ggttattttc atctgtgaat ttttcccata ataaactgat
    24841 ttttattcgt tcagcggcta gatagtcttg ttcgcgtgga taaaattcat caatcgcaca
    24901 aagtttttta tcacctgaat aaacaaatcc atataatgcg aaacgaactc ttccttttca
    24961 attggctctc ctaaaaattc cagtgacata ccatcttctc cttcctaaaa aaaataaaaa
    25021 agcagaaacc gatttggctt ctacttttct ttccttttat agctcttttt tacggaagaa
    25081 tccgcaaatg acattttttc aaaaaatcaa tcggcacaag ttcacgaaaa cttggagcaa
    25141 ttttggatag aatcacttcc ccatcttgta aaatacaatc ataaaaatca tcagttactt
    25201 gatacttacg cttcttacaa taattgataa aatagtagcg atcattttct atttccattc
    25261 gttgttctac taagcgcata cgaacatcat catagaaata agccacaaat cgcccttcaa
    25321 gttcatgttt ttcaatggga tactcttctg gtaacaatct attttttcgt cgtttataca
    25381 ttgctggata ccttagaaga agttcatcta aacgtctgtc agtatatggt aactgacgaa
    25441 tcaacgattc taatcgttct ttatacagat agaataattg gcgcaagcaa tagtgtaccg
    25501 cctctggatt ttctaatact gttggatcac gtgaccaata cgcaccaaca taaatcataa
    25561 tttttttcat ttagacaatc acaccagcaa tactaatgac cgatccacaa taggtagaac
    25621 aagtggcata gcgaccaatt tcctctaatt ctatctcaat ctcttctaaa gaaagatatg
    25681 tctgttcttc tgttggctgg cgactcattt cccaagtgac agtcaccaat gaaatttctt
    25741 ccataagagg tttttcgctg ctaagtgctg ccacacagtt ttcatatatc ttcattttat
    25801 cgcagccttt tttaaccgct aaaatcgcag gtattggcaa tgaaaatcga taaaagcgaa
    25861 tgaattctag ccttcctttc cttcggctaa attccaactc ttcgagttct tgttcgtatc
    25921 ccttacgaac ttctaataag cgtgcaattt cttgccagtt ctctttttcc tgataacgtc
    25981 cagcttttac cgcttgttca atataaggaa ctcgaaaacg aaaataagac aaatcaacca
    26041 tcttttcatt taatgcttcg attgcagcct ttaaatccaa caggcgcagc cattctgttg
    26101 tcgtatatgc attcatgcaa ttttccctcc tgacgttccc atccattcta gatagttttg
    26161 ttgctcgtca tttagttcgg cattatcaat cccttcttgt acaaagtctc ttcctaaaat
    26221 acgatctgct tcttgtaaca actttaatgt cggagctact tgtttcaaaa accagcgttc
    26281 tgaacgatct aatgagaatt tttctggctt tactgtaaaa tccaattctt ccatcgaacg
    26341 aaataatttt gcccatcgtt tatcaacaat ccgtgcatca ctttccagtc tatcccaaac
    26401 aataagtttt gcattaatta aaccaacgcc aatctctcct aaacgtttcg gtgaatcacc
    26461 taaaataaat gcttctactg cttgtgttgc tttctcattg gctaaccgta actcatatcg
    26521 attataaata ccatatttcg ttaatgcttc taattctgaa attttttctc ggttcgcaat
    26581 ttcaaaacgt ttctcataaa aattaaaaaa gagaggactc tttcgcgatc caaaatacaa
    26641 agataatcct tcacttcgaa aatagccatc atctaaaaaa caaccgccaa tattctggaa
    26701 tctcttaaag tccatttcta ataaacctgc tttttgtttt tctagtaatt caaagagatc
    26761 gaaatgttct tccgtttcca atccccaaag ttcatctaac gcaatatcga atcggctaca
    26821 ttgcacacgt gtataaccag cttccaactt tccttgattt ttccaaatgg aatatagcca
    26881 tgttcgccaa tctgtttgtt gttcacgcat gacttcctca tattcccggc aaccttgtcc
    26941 tgaaaattgc acaagtacat tttctgttac agttcgtttt gaatgccaga acacccagat
    27001 attcccacga acagaaagac agtcaaaaag atacaagccc gttggacgtg tttcaaattc
    27061 tgtcagatcc attcgtaata cacgttgaat cactgttttg tagtctgtcc caaaaaagga
    27121 aagacgcaaa taatcaatca ttgctcgaag atctattccg cttttcatat acaatcgaaa
    27181 gcgttccttg attcgttgtt caaaatcctc tgggattttt cttttccctt gttccatctt
    27241 tctaatgtaa tcttttgagc agcccatcaa ttgcgcaaat cttgcttgtg atagcggctt
    27301 tttatctcca cttatattat gaattgcact taacttcttt ctgtagcttt ttagctcaat
    27361 cggtgtcatt ttctcgctcc ttttataaaa taacaaaatc gatttttttt aaccctttag
    27421 aaacaccgat atatcaacta gtccccctcg ttttttggga aaagtagtac aactgctgac
    27481 cttagataat cacttgatac aaaagggttt ataaaacttt tttctatgtg ttatgttatt
    27541 tctgcccccc atattatata tcggggggct ttacacaaag aggccgtgcg caagcgcacg
    27601 acctctttgt gagctgcaca cgctgctagc gagtgcgcat tataggccca tgcttcgcag
    27661 ccttaatgcg caccgccagg cagagtgcgg ctaccagact acgtctagag ccctcccgat
    27721 agataataac tacaaaatta aatgatctaa ttttgttatt tcactatatt tttcaggaga
    27781 aaaaacgcga taaattgaca aagttaaatc ctcttctaaa tctactcgat aatgatacaa
    27841 tcgagtcaat cgttctatat cttttttcgt tagcaatact tgattaataa cttttcctgt
    27901 aaaaacacgt tctttgcgca aaaagcggta atcagttact tgttcaatac gattcaacca
    27961 atcataaaac gttctggaag aaagagaagg attaatcatt cgtattgctg tagctactct
    28021 ataataacaa ctctctgcca tttaacttca cctccttagt tgattacaaa atatgcgcat
    28081 cagaaaaact tgttcctttt ggatcttttg ctaaatacat ttggcgctct agttgttctt
    28141 gtaacaactg attatcatct cccatcgttt gatcttgact atcctctttt actgtaaaat
    28201 catagacaat catttcagta aatttctcaa attctttgat aaagtgataa tctttgtaaa
    28261 caaatggcgc aaaaaactct acaggtacat caaatcctgg aaaagcatat ccacgaccag
    28321 gttgatcttt gttgtaaaat ggcttatttt taaaatcttc tccaaaagtc attaaataac
    28381 caatgggaga caatcgacca acagaaatac ggaatgttaa attatcccga acaccacttg
    28441 gaaaatattc tgcatctggt cgttgcattg ctaaaataat gtacatccct gcttgacgac
    28501 cctttaatac taatggctga atcaatttat cgactctatt tctcgcttcc atatccaacg
    28561 aaccataaaa agctgcccat tcatcaaaaa agataaaatg cggtggtaac ccataataag
    28621 cataattttt ccctggttca tatttaggat ctttcatggt tttcatatag gcataccgtt
    28681 gattcatttc ttttaatgca tttcgtaaac aaataatcat ttcttcattt attttgtaaa
    28741 acacatgtcc tttgaataca tcgacgtcac ctaatgctgc taaatctgcc gcttttccat
    28801 cgcaaatatc tactgtccca acacttaaac aagcttgaat taaagaatac aataaatagg
    28861 ttttcccacc accgattgca ccagcaatca acatatttgg tgattgatca tatacccaat
    28921 ccaaagtttt cattaaatga atacgtccat tttctgctat acattgatca ataggaatcc
    28981 gaccagaatc tgaaaggaat acataattga ttcgggcttt ttctcgttct tcacgaatta
    29041 aatcacgcaa aaatacttca gataacaaat gacccatttt taaaaatcgt tcgtgaaaac
    29101 gcccaccatc taaaggaaaa gaaaccacta attcttgttt cttttgataa aaataaactt
    29161 ttggtaatct cattttttcc cttgtttgtt tctcactaac ttgtttcttt gtataaacaa
    29221 accgattgtc aattaacatt cgaacaagta actgacgcca ataaacagag gcaaaatatc
    29281 cttcttttag tcgcgaccaa tgcatcaacc ctaaaattaa cccactaacc agcaacaaat
    29341 acaacacaat acttattcca ggaataagat acatttgcca attcgaaaac gtacttaaac
    29401 gtggataaaa tactttccaa ctaaaccaac ctaacagaat caaaaatgga aacaaaaaga
    29461 aaccataata gcaaaaccat aaataacgat tgaaatagcg aattcgccga ccacgatact
    29521 tgaaaaaatg agctttcaat tgtcacattc ctcctttctg tttttacttt tcctgtgcta
    29581 aaaacttttg acaaaaagca actaatacag gaatatcaca tttagtaaaa aaacataatc
    29641 gaaaaagatt taatcgattt ttataagggt gtgcacacat attacatatt cgtactatac
    29701 gaatccaaat cacttcctga tgatcttgtt tccactggta cggtaatgaa aaacgaacaa
    29761 gatcacgtaa aaacatacac tgcccaataa ccgcacaaat atatgcattt gtttgtacaa
    29821 aaatcgttgg attgtctcca aaatactcaa tcaattgttg gatattttga taacaagcac
    29881 aatctctcaa agtatttgat tggttttatc tgaattcaaa atctcccctt ccttctatct
    29941 tagataaaaa gaataggaag actccttcct attctttcaa aaaaacctta ttttttctct
    30001 ttttccttag aatcaacact tggttgtttt tgatctaaac ctttttcttg tgattgtttc
    30061 atattaggat tatttgttgg agcttctact ttctctaatc ctttcgcata aatcactaaa
    30121 tctgaatatt cacgattgcc atcttgtgct ggaatatata ccacatgata ttctggatca
    30181 attaatttca caggatcacg tcgtttaaaa ccagtcaaat ctacatctgc tggaaattta
    30241 actcgtcgtg caatctttgg ttcatctgga tttccaaaaa ctaattgtgc tcgctgtgat
    30301 cgaatttctc ccgtataatc gcctgtttca ttatcaaata cacgatcaga ctcttctaat
    30361 gcgccaaagc gtacggctcc taaacaagtt tcatctaatg cttctgtaat gtcataatta
    30421 tttggaaatt ttaatcccat cttacaaaac ctccccaatt tttacaccag ttaaaaagac
    30481 accaacatct tgatagccag ttgttcgacg ctctgtttgt cccatatcat ttgtttcacg
    30541 actattcact cgttctttac gaaaaacaaa ataagcttct tcaaatgaaa tacgcacctc
    30601 tttttctggt aatcgtaatc ttttatcctc ttcagctgtg agataaacaa aaaaagcagg
    30661 ctgttcttct cgcgaacact ctgcttgtaa ttgaacatat cgcccagaca caccattaat
    30721 ttcctttggt ggattaggtt cccgtgaacc caataaaaat acttgaccta aaaactcttt
    30781 cttcatacgc aatgcttttt ctgccataaa gtttttcctc ctcttaaaaa ccaaaataaa
    30841 ttctaaatat ttctacatta caatcaaaca agcggttaaa aatcctaacc gcttgttcct
    30901 catgactaat ctttggcttt acgtacttta taaagtgtta tacctaaagc aatgactaat
    30961 actactaatc caagaaccat aagtatacta cttgtttgtt cacctgtttt tggcaacatt
    31021 ggtacaacag tagctggttt aacccgttgt tctggtttca ctggttgcgg tggttttggc
    31081 gcttccacaa tttgaaccgt ttgatctttg tttgttagat ctacattgtg tttcgccact
    31141 tcttcaaacg tttctttctc atcttccgtt ttcgcttgga gccattccgc aaaactcaag
    31201 ccttttcctg caagattgcg accgtccact aagaattcaa ataagaattc catcatttct
    31261 ttatcggccg caaagacttt ttccgcatga gtgccttcaa atggtgtgcc gtctggtgtt
    31321 aagtagcctt gaacaattaa gcgatagatt tgaccaatcg caagaccgtc tactttgacc
    31381 cattcaagca cagtttgatt tggcaaggcc aagatctctt ttccgccatt tttattcgtc
    31441 gctttcgtcg taatggttgg attactgatt ttgatggttt ggtcattgtc ggtaatatct
    31501 gcgtgagaag ccaataatac gccttctcta aacagatctt caaagaccac gacttctttg
    31561 cctcgcaacg cacgtgcgtc tagaataaag tctagattga ctgtaccatc cgttgtttct
    31621 gccacaaacg ttaaggtact tgtgacttct tttccatcta ctagcactgg tttttccgtt
    31681 actttgtcca ttagaacacc gttgactgtg tatgtttttc caacgaccaa atcgtggtat
    31741 ttcacagcgt ctgtaatggt gactttcgtt aatggattaa cctctttcaa gccagtgggt
    31801 ttatgtgtag ccgttgtacg tacacttggg ttagttactc gtaccgtttg ccctttgtcg
    31861 ttgatgtctt tatggtttgc tagttcttca tcatttctaa aaagactttc aaacacgacg
    31921 atttcacgac catttatacc tgtcaaatca aaggtaaatg gtacgatcac cgtttcattt
    31981 tctgctttgg caataaagcc aacactcgtt tctaccgtat ttccatgcac aagcaagggt
    32041 tcaccggttg ctttatccat taagatccct ttgaccaagt atgcttttcc tggaagaatc
    32101 tcggtaattt caacggtatc gtttaaggta aacaatcctg ttgggtctgc gactgtcaat
    32161 ccgtcttcaa agacagccgt ggtatgaacg gttggattat tcactttcac actttgggct
    32221 tcatcgttga tatccgcatg tgctgcaact tcaatgccat cacggaaaag tttttcaaaa
    32281 acaacgatcg tttgaccttt cagaacacta gcattaacca caaattcaag gtcttttgtg
    32341 ccattgactt tgtctgcaat aaaggccaag gtacttgtga tttctttgcc atcttgtaaa
    32401 attggcgcat tcgttgcctt gttcatcaat actcctgaaa tggtgtattc ttttccgaca
    32461 aacaagttgg tataagaaac actgtcttta atgacgatcg tttctaatgg atcaaccact
    32521 ttttcaccat cggctttatt tgacgcttgt gtttctagtt ttggtggaat caagtaatta
    32581 cgtacagaaa ccactaacgt ttccccatca tctggcgcat tttgtttgaa tgcaaccgtg
    32641 aatgcttgtt tatctgtatt tggttggaaa ctttctaatg gggcattttc caagaagtaa
    32701 tagtcatcgg caactagacc tttcactaaa atttccccgt tttgatcagt ggtatattca
    32761 ccaattgctt gatttttacc gttatacaag gtaaagttca cacctgcgag cggcgttttc
    32821 ttcttgttcc attcttcata cttgaataat tttacacttt tccgtgcttg acggttcgca
    32881 aaatggatca ctttgatcgg ttctgtatca ttggtaatcg agaacactaa tgggttttga
    32941 ttcaaaacgt aatttacggg ggctttgatt tcttccaaac gatagcgatc ttttccataa
    33001 gtaagtgtac cgttagttag gaaaaagcct ttttcattgg ttttaaagat atccgttgtt
    33061 tctgtatcat ttggaatctc cattgtgaca taacgattgg ctaaagtatc aaaaatcttg
    33121 aattctgtat tagcaagtgg aatcactttt cctgtttctt gatccacttt caccacttta
    33181 agacgttgtt caattacttt atcttctaaa acataatgga aagtttgccc attttcagaa
    33241 attgtgactt caagtggttc aaatagttta tacccttctt ttcctttggt ttcagaaaga
    33301 atgtacgtat caaagacaac ggtattttta ccaaaagtag cataaccatc attgtctgtc
    33361 acaacggttt tcaccacttt gccagttgtt tttgacgtca aagtgatttc aatgccagct
    33421 aattttggtt tgttatctgg attcgttgaa tcgactaaat ctttattagc aactttcact
    33481 aaatcaatgg ttcctttgat cacttgatct tttgcggtcg cattgacagt ttttccaggt
    33541 tcaacaacaa tttcaattgc ttcatcagaa agcacataac cttttggcgc tttgatttct
    33601 tttaaaacat atttgccagg atcaagatct ttaatttctg cctgtacttt gccgttaatt
    33661 tttttcaagg taatttcttt aatctttttc ccatctgctt gatacaaacc atagaccgca
    33721 ttttctaaag aagctgcacc ttgtgctttc acaccagttt ccgcatcttc tttaaacaca
    33781 cgaatgtttc cttgttttag aatttgtaaa ttaataacag acgcattagg ttctgttgga
    33841 tgtaacacac caattgtttg agctcctgga cgacgatagg ctaatggcgc accttgaact
    33901 ttaattttat tcaattgaat ttttgcttta tccggtgcct cttttgtgac tgtaatccat
    33961 acttcattgc cgtgaataga tacattgaca ccttttggtt tttgaatgtc tttcacatat
    34021 ttcaaaaaat catttttatt ctttactttc aacgtttcgc caatttttac cgtatgtgtt
    34081 tgattattaa aagttgcttt ttcaccaaag ttattaatca aacgttgaat ttctgctttt
    34141 cgacgatcat aatcaacacg gatatttttg attgggattt ttgtgcccaa agcttcccaa
    34201 atcataaatt gtgccgcaat gtattgttca tcggatttgt ctttatttgt gacatatcct
    34261 aaataagaga tcaagcttgt ttttttccgt acatttgaat ttttcaaata gtttttcaaa
    34321 gcagtagctg tataaacttg accttctgcg gctgagacac caggctcaat acaaaacgcc
    34381 acttgtccat taatctcaaa acgaaccata taatttaaag tgaagtttag attgttcgga
    34441 ctagaagtaa caccaatatt ttcgccccaa tcaattttcc gaccacctaa aacagctgca
    34501 ttggttgcac ggcgaacacg aaccgaacga ttggttggta ctgttactaa cagtgtaggt
    34561 gtacctgttt ttggaatgtt ctgctctttt ttcttttgat tttcaatact agccgtagat
    34621 tctttgtttg gtttcgttgg ttgattttga ctagctgcgg ttgaagagat tgttttttca
    34681 acgttttcct cattttttcc ttctttgtca gcagtagccg ctggttgttc cactgtttct
    34741 tctattcgtt tcttttcttc cgcttgtttc tcagaagact ctggctgcac agaaggcgtt
    34801 gcttcggcag ctttttctcc ttctagagtg gacgtttctg aagcaggggt tgtaattgag
    34861 gcagtttctt caactggttg tgaagtacca ggactattcc ctgggtgttg tgtttcccca
    34921 atcgtctgat cgagagtcgt tttggaattg accgttggcg cttctgtcac aggggcctgt
    34981 tcaacagtgg cttcaccagc tgggaccccg gcttctgctg gttggacttc tgtcacttca
    35041 gaagcgactt gggcaatggc ttccatcgta ggttgtatag ccgtcgtttc ttctgcatgt
    35101 gcttgagcag ttcccaccaa gaaacagaat tgagaaaaag ccaccaatgc gagtgctttc
    35161 aaccaattca ttttcgtttt tgcatacaca agaattcctc cttttcctga gaattttata
    35221 taataaaaca aaacgccgtt accaaaagtg ataacgacgt gaactgtctc ttctattttt
    35281 atctggcgct cttatctgaa cacatttcat caatgatttt accctcccac tataattaca
    35341 gaacaaaaaa agaacctgct tcgtggaaat caactgtcca tttcccaatt ggaataccag
    35401 cttttttggc aacttcacca tcaccaaatc tcatgccata ccaattacta ccttcatcct
    35461 taatttcttt ccaaccatat gacatagctt catctaatga atcaaaaatc atgacactat
    35521 tgccaattgt tacaggatct ggcttaagat cttctggaag agaaatatca atcataccat
    35581 aatgatccga ttcctcagta ttattgtcat tactagctac tggtttggtt gttctactgg
    35641 cttattttga tacaacaagt actcttattc ttcttttact tctccgtttt caatttccca
    35701 ttcaaaccac tccgcaaagt cttgcttaaa accatctact cgatacctat tttgtaaata
    35761 ggcatcttct gacgtcgtag gatctaaata ggtaggttta ttctctggac gagcatagac
    35821 acctacccat gtttcgtaat ctccttcaaa ataactatct accaaatagc ctttttttct
    35881 aagaatctcc cgaacttgat ttttaattat tgatacttgt tcaaaaccat cactcattct
    35941 atcacctcaa ataactctag attctcataa atattcccga caatttcaat cctatcaatg
    36001 atctctaaca aatcgctact tatgcttccc cattcgtata agaatttccc ttccgcaaaa
    36061 taaattttcc ataaacttct tcatgatcgt cccaaccaat atcactctcg aaaaattcca
    36121 cgttgttctt atcttttagc tcagtaaatg ccataagttc aacatgtttt ccaacctcga
    36181 aacaatcaca ccacccatca accgttacac gtgtgccttc aatacctaag aaactttgtc
    36241 ctcgtgtatt aaacactaaa actttccgca ttttttgctc attaattaat cacgcgcgaa
    36301 atctaggaat cacaacttat tcgcttcttc tttataaata aaaaaactcc aataatcgga
    36361 aattactatc ttttcctcat tcctttttta aatcttcata cttcttctta tctttgtcct
    36421 aacctaataa cacaaatttt gaagaaaaac tcagtaaaac ctgattcttt ttttatcttc
    36481 acaacaacca actttttctt cagatccttt tactagaact tgtatacaaa aattgttgaa
    36541 tgctgatata atttgcggct acttgaaaaa acgatagatg taaaaagata aatagaatca
    36601 ttttttattc tatatcagtc tatgattcat tgcttatcaa tcacccaacc cattcgatgc
    36661 cgtttttttt agagaaattt aaaaaagacc gtacgaatct cgcattatcc gattactttt
    36721 ccagaaaaga tccccaattc tgtataaata accctatctt cttgttggtt tcattttctc
    36781 atataagaat tcagtcaatc tacccactat gaccattact acgtccaaca caactgacat
    36841 attaaccacg taagtattcc ctcacagatc tccgaatctc catggtatgg attcccatcc
    36901 tgacgctgca gaggacaaca tatttcatgt ggctctgtac ccttttgatt tggaaacact
    36961 acaaatcaat actcatctat aacttatcaa gcgaactttc gctaggcttc tagtgattac
    37021 taaattgttg gataacatac atagcccatt ttatctagct gttattcata acagttagtt
    37081 cttgtattac ttcttccgct tgtgttgcca ttgagcttgt caaaaagtta cttagaaaaa
    37141 agctgccagt aaagcaactt tcaacaaacc ctttttgttt cttatcatat caagaaacct
    37201 ccttttataa attttttcta taataaaaaa cgtcgataac ttaataagta tcgacgtaaa
    37261 ctatttttat atcccgtaaa tcaaaaattc taaagaaaga tttcctatat aagcatattg
    37321 gataattcga ttagtattgg gtatatctct accattctca tacctatcta tggaccattt
    37381 tgaaattgaa ggagaaaaaa gctttccaaa ctcctccctt tctagataat aatctttcct
    37441 aattttcctc atccttaatc ccatactaaa agaatttatc tttttaaaat cgctaactct
    37501 ttcatctttt ggaagtatat tcttataatc ttctccgtac ataaggtaag gaacagtgac
    37561 cttaccaaga taggcaatat tcattagttt ttcaatatct ggaatattaa tacctttttc
    37621 ccatctactt ataacatttt tgcctgtata gatggtaaag tttttaccaa atttttcaag
    37681 cgtctcttcc cggttctttc ggacttctcg tattcttttt cccataacaa ttttatcgtc
    37741 ttttgataaa ctaaatatct cactatcacg attaatctcc ttcaaaattt ctttttcatt
    37801 acttaataga aaaatatcga tttttttttg catttctttt gacggatttc tctttctatt
    37861 taacacataa ctgagtaata cttcactaat tcctatatta tcagctaact ctttgttaag
    37921 taacttattc atatctctgt atgcaattag tttaccgatg agaatctcaa tcttatcttc
    37981 ctcatctttt attagagttt ctatattcag aatcttgctt agagtattat ctacgtcttt
    38041 agggattttt cttgacgctt tttcatattt aactaaagta ctttgtgaaa tacctgctaa
    38101 atcagctaac tttttttgag atagtttttt ctcttttctt agagatttaa gaacccttcc
    38161 acttgaatta tcaaccatga aaaaagcacc tcctatgaga tgctttcatc atatactgac
    38221 agctaaaaat cttcaagaaa aatattccaa ttttgttaat tttagtatcg ccgtgataac
    38281 caaatgacag tttaaaatct tttatacaga taatcctcag tgttgcatct actcaaaaag
    38341 gtttatttaa taggtttttc gattgattat aagttatttc acactatctt gctcatccat
    38401 tttcagaacg gccatgaagg cttcttgcgg aacttcgacg gagccgattt gtttcatccg
    38461 cttcttccct tctttttgtt tctctaagag tttacgttta cgagaaacat ctccaccata
    38521 acatttagcc aagacgtttt tacgcaaggc tttgatgtct gaacgggcaa cgattttttg
    38581 tccaatagct gcttggattg gcacctcaaa ttgttggcgt gggattagtt ttttcagttt
    38641 ttcaacgatt gcttttccac gttcataggc aaagtctcgg tgaacgataa agcttaatgc
    38701 atcgactttt tctccattca gcaagatgtc catcttcact aacttgcttt tttgataacc
    38761 agacatttca taatccaatg aggcatagcc tttcgtgctt gatttcaatt tgtcgaaaaa
    38821 gtcaaagaca atttcagaaa gcggaatatt atagacgaca tttactcggt aatcatctaa
    38881 ataatccatc gtaatgaatt ctccccgttt tcgttgagaa agttccatta ctgcaccgac
    38941 aaaatcattt gggaccatga tctgtgcttt gacgaatggt tcttctacat cctgaatcgt
    39001 tacaggttca ggaaaatctg ccgggttatc tactgtagca gtcgtaccat ccgttttatt
    39061 aacatggtaa ataacggatg gtgcagtcgt gatcaattct agattgaatt cccgttccaa
    39121 gcgttcttgg acgacatcca tatgaagaag tccgaggaat ccacagcgga acccaaaacc
    39181 taatgcttga gaggtttctg gttcgaattg taaagcagca tcattcaatt gcagtttttc
    39241 taaagcttcc cgcaaatcgt tgtaacgaga agtatcaatt ggataaagac cacaataaac
    39301 catcggattc atttttcggt aacctggtaa agcttcagcg gcaggattgt ctgctaacgt
    39361 tactgtatcc cctactcgtg tatcttggac agttttgata cttgctgtga tataaccgac
    39421 atcaccgacc atcaaaaagt ctctagcaac tgcttttggc gagaagaccc cgacctctgt
    39481 aacatcaaat gttttgccat tactcatcag tttgattttg tctccgggtt tgaccatacc
    39541 gtccgtgatc cggacattta gaacaacacc gcggtaacta tcataaatag agtcaaagat
    39601 caaagctttt agcggtgcat ctaagtctcc acttggtgca ggaacatatt ccacgatctg
    39661 ctcgagaata tcttcaatcc caatccctga tttggcactg gctaatacag cttcactagc
    39721 atcgattccg attacgtctt cgatttcttg acggacacgt tcgggatctg ctgcgggtag
    39781 gtcgatttta ttgatgactg gcaggatctc caaatcattg tctaacgcta aataaacatt
    39841 ggccaatgtt tgtgcttcga ttccttgtgc tgcatcgacc actaaaacgg caccctcaca
    39901 ggcagcaagg cttcgagaga cttcataggt gaagtcgacg tgccctgggg tgtcaatcaa
    39961 gtgaaagata tatgtttctc catttttcgc tgtgtaattg agttctacag catttaattt
    40021 aatcgtgatt ccacgttcac gttccaaatc catcgagtct aacagctgat cttgcatttc
    40081 gcgagacgtc acagtgtgcg tcatttctaa aatacgatcg gccaatgtag atttcccatg
    40141 gtcgatatga gcgatgatcg aaaaattacg aatctgctct tggcgttctt tcattttctt
    40201 tatatccata gcgtctcctc ttttcatata atcagcactt tccattatac caacgaaaag
    40261 cagtaattta aagagttttt aattagtcag ctatagaagt tttttttgta gaattttgct
    40321 atactgttat caagctaata aatggagatg aaaaaatgga tcaaaaagat tttagagaaa
    40381 atcttgaatt aaaaccggtc actcaagaac atatcgatca attcaatgaa ttgctttcct
    40441 atgtgttcca agtgactgaa gcagacatcg aggaaagcgg gtttgagaat aaacgagctt
    40501 ttatccgttc caaaaaaccg attttggaag tatcgaaagt gttcggatgg ttccacgaaa
    40561 ataaactgat ctctcaaatc gctatctatc cttgtgaagt caatattcac ggtgcacgtt
    40621 ataaaatggg tggtgtgact ggagttggaa cttatccaga atatgctaac catggattga
    40681 tgcaagatct aattatcgtt gcattggata atatgcgcaa gaataagcaa tggatctctt
    40741 atttgtatcc ttacagtatc ccctactatc ggcgtaaagg atgggaaatc atgtctgata
    40801 aactttcctt taaaatcaga gatacacagc tacctaaaca aatcccagta agtggtatgg
    40861 ttgagcgatt accagttgat catccagacg tattttccgt ttatgacaaa tttgcccaac
    40921 aaaaccatgg tgctttattc cgcagtgatt ttcattggga agagtattgg cgtttcgaaa
    40981 atgaagatga gcgcacagcc gctgtctact acgatagcaa ccatgaacca agaggtgttc
    41041 tgttctactg ggtagctgaa gaaatatttc acgtaaaaga aatgttctat cttgatcaag
    41101 aagctcgaaa tggcttatgg aactttattt ccgcacattt ttccatgatc tactgggtac
    41161 atggagatat ttataaaaat gagcctttag catttttgat tgaagatagt cagatcaaag
    41221 agcagatcga accatatttt atggctcgga tcgttgatgt aaaagaattc cttcaacggt
    41281 ttccgtttgt tggaacagct gatgcttttc atttcatcat tgaagatcct gtcgctcctt
    41341 ggaataatgg tgtcttcgct ttaacatggg atgaacaggg acaagtccgt gtcttaaatg
    41401 aacctatagg aaaatccgtt cgactggata tccaaacatt gacttgcttg atgatgaatt
    41461 atcgccgtgc ttcttatttg gcaagaatcg aacggttaga aacagatgaa gaaacactga
    41521 agtcactaga gcgtatcatt ccaaacatgg aagcttactt tagcgattat ttttgataaa
    41581 aaggatgatg tttagatgaa aatttatttt gccgcaccaa tgtttgctaa aagtgatttg
    41641 ttatataacc aacagttagt taaagaaatc agagagctct cttctgagct ttcgatctat
    41701 cttcctcaag aaaatgaagc aatcaatgac aaaactgctt atgcagacag tcgaatgatt
    41761 gctcttgctg acacagaaaa agtgttggct agtgatttaa tgattgcttt actagatggg
    41821 ctgacgatcg atgccggggt agcatcggaa atcggtgtgg cttatgcgaa aggcatccca
    41881 gtgatcggct tatatactga tactcgacag caaggcggaa cccacccgaa aaaaatcgct
    41941 gcactacaag aaacagctga aaatcaattt cactacctga acttatatac aataggtttg
    42001 atcaaattga acggaaaagt ggtttcttca gaaattgagt tgctttcaga agtaaaaaga
    42061 tttttagatg gagggacttt cagtgattaa agaaatcaaa aaggtgcaaa tagctttact
    42121 tgcttttggt gtattcgttg tctgctataa tttttatgaa tttatcacac aaaaatattc
    42181 gacttctcaa ggaatcacat ttatcgtgga atctttatta gggattgcat tgattttcat
    42241 gccacaagtc attttgaaag ttttcaaact taaaatacca gcagcaatcg ttttgtttta
    42301 ctggtttttc ttgttcatct ctgtcttttt aggcacaggg atgcatttga tcagtatcat
    42361 ctctttttgg gacaaaatct tacatgcggt gagtccaatg gtcctgacag ctcttggcta
    42421 tggattgatt ggttacttga tgaaagatgc tgagatatca aaaaccagtc cttggttgtt
    42481 cctcttattc ggctttgcgt ttgctggact ttgcggcgtg ttttgggagt tctgggaatt
    42541 cttatgcgac cagttcttag gcatgaatct tcaacgtttt gctgcttctg atggcacact
    42601 gtttgtcgga cgagcagcat tgatggatac gatgggcgac ttgctgacaa atacgatagg
    42661 tgctgcctta atgggattgt ttgcatggtc tcaaagtaaa aaagatgagc gttactttga
    42721 aagttataaa ttagaaaaag tgaaaaatac ctaataaaag aggttgtgac agaagcgggc
    42781 agcttcaaga aatttcggct tatttttcga agaaactact tctggaacac tgtttatttg
    42841 aaaaaaggag gtctgacact agttgtgtca gacccctttt ttcttttata gtctcaatgg
    42901 aagattagac gatttcttct agctcttctg ttttgaaatg aagttgtcca tcaagtaaag
    42961 taatcgttac ttttgattta ggcataacat gtcctgcaac gatttcttta gctagtggtg
    43021 tttctacttc cttagtgata aatcgtttca atggtcttgc accatatgct ggttcataag
    43081 cattttcagc aatccacgtt ttggcttcat cactgattgt cagcaggatt tcttgatgtt
    43141 ccagacgttg tgccaattgc gccaccattt tgtcaacgat tcctttcacg ttgtctaggc
    43201 tcaatggtgt aaataaaatc gtgtcgtcga ttcggttcaa gaattctggt ttgaagtttc
    43261 cacgtaatag cgtgttgact tgttcagcca ctgcttctgg aatcgttcca tcagcagtca
    43321 cgccttccag cagtaactgt gaaccgatat tgctggtcat gatcagaacc gtatttttga
    43381 aatctactac tcgccctttt gaatcagtca agcgtccgtc atctaggact tgtaacaaga
    43441 tattgaagac atcgggatgc gctttttcga tttcatccaa caagacgatt gtataaggat
    43501 ttcgtctgac agcttccgtt aattgaccac cttcttcgta acctacatag cctggaggag
    43561 ctccgactag acgagacaca gcatgttttt ccatatattc actcatatcg atccgtacca
    43621 tatgatcttc tgagtcaaac aagttctcag ctaacgcttt cgctaattcg gtttttccga
    43681 caccagttgg tcctaggaaa aggaaagaac ctagaggacg atttgggtct tgcaatccag
    43741 cccgtgaacg aattaccgcg tcactgaccg catcaactgc ttcatcttga ccaatcactc
    43801 gtttatgaag tgtttcattc aatttaatta gtttttctcg ttcaccttct acaagtttcg
    43861 ttacggggat acccgttaat ctgccaacga cttgagcaat ctcattttcg gtaacggact
    43921 cttgaaccat cttaatctcg ctgtcttttg ctttagcttc taattccttc aattcttttt
    43981 ctaattgagg tatcgtacca tgacgcaata cagcagcgcg ttctaaatca tagttatttt
    44041 ctgcatcttc taattcgtgt tttgctttat cgatttcagc acgttttgct gaaacagaat
    44101 tgacttcttc tttttctgtt tcccactgca tcttcatcgc atttgcttct tcacgaagtt
    44161 cagctaattc ttcttgcaaa tttttcaagc gttttttact tgcatcatct gattcttttt
    44221 tcagtgcagc ttcttcgatt tccaactgca tcaaacgtct agtaacttga tctaattccg
    44281 ttggcataga gttcatttct acccgaatcg ttgcactggc ttcatcgatc aaatcgattg
    44341 ctttgtccgg taagaaccga tcagtaatat aacggtcaga taaagtagct gctgctacta
    44401 atgcgttgtc atggatgtta acaccatggt ggatctcaaa acgttctttt aatccacgca
    44461 gaatactgat cgtatcttcc actgttggtt ctttgactaa taccttttga aagcgacgtt
    44521 ccaacgcttt gtctttttcc atatattgac ggtactcatc taaagttgtg gcaccgatca
    44581 aatgtaattc accgcgagca agcattggtt tcaacagatt tccggcatcc atacttcctt
    44641 ctgtttttcc tgcccctacg atattgtgga tttcatcgat gaacaagagg atacgtccat
    44701 cacttttttt gacttctttc aagactgctt ttagtctttc ttcaaattca ccacggaatt
    44761 ttgctccagc gatcaatgca cccatatcta atgaaaaaat cgttttatct tttaaatttt
    44821 caggcacatc tttgcgtacg atacgttgag caagcccttc aacgattgcc gttttcccta
    44881 caccgggttc tcctatcaga acaggattat tttttgtttt tcgtgaaaga atacggatga
    44941 catcacggat ttcttcatca cgaccgatga ttggatccat ttttccgctt ttgacttgct
    45001 gtactaaatc aacgccgtat ttttctaatg ctttgtattg ttcttcttgg ttttgtgagg
    45061 tcactctttc tcctcctctc atctcttcga tgtttttacg caattctttt tcagataatc
    45121 cgtttttatt caaataaaca gttaacggat aattttttaa tttcatcaac gctaaaataa
    45181 cgacttccgt tgaaagaaac tcgtcgccga agctttcacg tatttggtct gcttcattca
    45241 ataatcgaaa gaaattctgg ctgaggtttt gtccatattg gacgtttcca ccagaaacaa
    45301 ctggatactc atccagtaga cgatcaattt catgttcaaa agattcgaca tccaatccgg
    45361 catccgtata gaaatttcga ccaaaatgat tagattgtaa aaagattttc catacatggg
    45421 caatgtcgat atcttgatgt tttcgagtga ccgcaatctg ttgagcttca gcaatcgctt
    45481 cttgaagcgt cgtagtcatt ttctcaatat tcatacaggt ataccctcct aattaaaggt
    45541 aagatcactt atttctttga tctttacaaa aactattata tcgctttggt caattttggt
    45601 caaaatatac acatagtttt ttgacttttt ttctcgactt atataaatct taaaaaaaca
    45661 aaattgattg tatgtatata aaaaaagagc caaacaaacg taaaattatc ttatccataa
    45721 cgtttttctt tgatttgata aaaagggtag atcttataaa a
//
LOCUS       DADQDV010000018        44934 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.018, whole genome shotgun sequence.
ACCESSION   DADQDV010000018 DADQDV010000000
VERSION     DADQDV010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 44934)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44934)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44934
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.018"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            5..1849
                     /locus_tag="J8S10_001034"
     CDS             5..1849
                     /locus_tag="J8S10_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629632.1"
                     /translation="MSFFNNIYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSP
                     ADSNQMKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLL
                     IKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNY
                     AGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSL
                     ILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKK
                     WYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNR
                     FYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNT
                     DKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKN
                     YVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDD
                     LAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGIT
                     EELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
     gene            complement(1894..2898)
                     /locus_tag="J8S10_001035"
     CDS             complement(1894..2898)
                     /locus_tag="J8S10_001035"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HAZ9629633.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(2909..3649)
                     /locus_tag="J8S10_001036"
     CDS             complement(2909..3649)
                     /locus_tag="J8S10_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAZ9629634.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            complement(3719..4522)
                     /locus_tag="J8S10_001037"
     CDS             complement(3719..4522)
                     /locus_tag="J8S10_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HAZ9629635.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            complement(4522..5604)
                     /locus_tag="J8S10_001038"
     CDS             complement(4522..5604)
                     /locus_tag="J8S10_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HAZ9629636.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            complement(5745..7013)
                     /gene="dltD"
                     /locus_tag="J8S10_001039"
     CDS             complement(5745..7013)
                     /gene="dltD"
                     /locus_tag="J8S10_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HAZ9629637.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            complement(7016..7249)
                     /gene="dltC"
                     /locus_tag="J8S10_001040"
     CDS             complement(7016..7249)
                     /gene="dltC"
                     /locus_tag="J8S10_001040"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HAZ9629638.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWCTPNKIIQQATALKG"
     gene            complement(7294..8499)
                     /gene="dltB"
                     /locus_tag="J8S10_001041"
     CDS             complement(7294..8499)
                     /gene="dltB"
                     /locus_tag="J8S10_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HAZ9629639.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            complement(8496..10010)
                     /gene="dltA"
                     /locus_tag="J8S10_001042"
     CDS             complement(8496..10010)
                     /gene="dltA"
                     /locus_tag="J8S10_001042"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HAZ9629640.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            complement(10021..10170)
                     /locus_tag="J8S10_001043"
     CDS             complement(10021..10170)
                     /locus_tag="J8S10_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HAZ9629641.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            complement(10451..12493)
                     /locus_tag="J8S10_001044"
     CDS             complement(10451..12493)
                     /locus_tag="J8S10_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9629642.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            complement(12483..13250)
                     /locus_tag="J8S10_001045"
     CDS             complement(12483..13250)
                     /locus_tag="J8S10_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9629643.1"
                     /translation="MEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGEFVGIMGPSG
                     AGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQEFNLIDTLN
                     AKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQRIAAARALV
                     VQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTASYCDRILFIK
                     DGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            13576..15765
                     /gene="nrdD"
                     /locus_tag="J8S10_001046"
     CDS             13576..15765
                     /gene="nrdD"
                     /locus_tag="J8S10_001046"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HAZ9629644.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            16080..16682
                     /gene="nrdG"
                     /locus_tag="J8S10_001047"
     CDS             16080..16682
                     /gene="nrdG"
                     /locus_tag="J8S10_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HAZ9629645.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(16736..17857)
                     /gene="dinB"
                     /locus_tag="J8S10_001048"
     CDS             complement(16736..17857)
                     /gene="dinB"
                     /locus_tag="J8S10_001048"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HAZ9629646.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(17966..18838)
                     /gene="rsmI"
                     /locus_tag="J8S10_001049"
     CDS             complement(17966..18838)
                     /gene="rsmI"
                     /locus_tag="J8S10_001049"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HAZ9629647.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            complement(18907..19254)
                     /locus_tag="J8S10_001050"
     CDS             complement(18907..19254)
                     /locus_tag="J8S10_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HAZ9629648.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            complement(19247..20071)
                     /locus_tag="J8S10_001051"
     CDS             complement(19247..20071)
                     /locus_tag="J8S10_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HAZ9629649.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            complement(20107..21045)
                     /gene="holB"
                     /locus_tag="J8S10_001052"
     CDS             complement(20107..21045)
                     /gene="holB"
                     /locus_tag="J8S10_001052"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HAZ9629650.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            complement(21059..21388)
                     /locus_tag="J8S10_001053"
     CDS             complement(21059..21388)
                     /locus_tag="J8S10_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629651.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            complement(21403..22047)
                     /locus_tag="J8S10_001054"
     CDS             complement(21403..22047)
                     /locus_tag="J8S10_001054"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HAZ9629652.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            complement(22111..22707)
                     /gene="recR"
                     /locus_tag="J8S10_001055"
     CDS             complement(22111..22707)
                     /gene="recR"
                     /locus_tag="J8S10_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HAZ9629653.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            complement(22732..23046)
                     /locus_tag="J8S10_001056"
     CDS             complement(22732..23046)
                     /locus_tag="J8S10_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HAZ9629654.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            complement(23066..24811)
                     /gene="dnaX"
                     /locus_tag="J8S10_001057"
     CDS             complement(23066..24811)
                     /gene="dnaX"
                     /locus_tag="J8S10_001057"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HAZ9629655.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            25026..26273
                     /locus_tag="J8S10_001058"
     CDS             25026..26273
                     /locus_tag="J8S10_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virion core protein"
                     /protein_id="HAZ9629656.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            26298..27482
                     /locus_tag="J8S10_001059"
     CDS             26298..27482
                     /locus_tag="J8S10_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HAZ9629657.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            27479..28276
                     /locus_tag="J8S10_001060"
     CDS             27479..28276
                     /locus_tag="J8S10_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HAZ9629658.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(28718..29374)
                     /locus_tag="J8S10_001061"
     CDS             complement(28718..29374)
                     /locus_tag="J8S10_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAZ9629659.1"
                     /translation="MDSRVLKEYLDKNDFPIIRKGYHKYLTFEGMEDSHTYILKEGTV
                     KASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESEYAEFYRINRVRFW
                     QNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLYELYDLFGVRTEEG
                     MLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIVILNMDLLEDNIIF
                     "
     gene            29567..29845
                     /locus_tag="J8S10_001062"
     CDS             29567..29845
                     /locus_tag="J8S10_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629660.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            29864..31072
                     /locus_tag="J8S10_001063"
     CDS             29864..31072
                     /locus_tag="J8S10_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAZ9629661.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(31220..31585)
                     /locus_tag="J8S10_001064"
     CDS             complement(31220..31585)
                     /locus_tag="J8S10_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HAZ9629662.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(31732..32505)
                     /locus_tag="J8S10_001065"
     CDS             complement(31732..32505)
                     /locus_tag="J8S10_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAZ9629663.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            complement(32679..33539)
                     /locus_tag="J8S10_001066"
     CDS             complement(32679..33539)
                     /locus_tag="J8S10_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HAZ9629664.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            complement(33539..34957)
                     /locus_tag="J8S10_001067"
     CDS             complement(33539..34957)
                     /locus_tag="J8S10_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAZ9629665.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            complement(35014..35463)
                     /locus_tag="J8S10_001068"
     CDS             complement(35014..35463)
                     /locus_tag="J8S10_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAZ9629666.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            complement(35908..36171)
                     /locus_tag="J8S10_001069"
     CDS             complement(35908..36171)
                     /locus_tag="J8S10_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HAZ9629667.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            complement(36270..37565)
                     /locus_tag="J8S10_001070"
     CDS             complement(36270..37565)
                     /locus_tag="J8S10_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HAZ9629668.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            complement(37562..38833)
                     /locus_tag="J8S10_001071"
     CDS             complement(37562..38833)
                     /locus_tag="J8S10_001071"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HAZ9629669.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            complement(38999..39868)
                     /locus_tag="J8S10_001072"
     CDS             complement(38999..39868)
                     /locus_tag="J8S10_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HAZ9629670.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            complement(40160..41770)
                     /locus_tag="J8S10_001073"
     CDS             complement(40160..41770)
                     /locus_tag="J8S10_001073"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HAZ9629671.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            complement(42963..44303)
                     /gene="glnA"
                     /locus_tag="J8S10_001074"
     CDS             complement(42963..44303)
                     /gene="glnA"
                     /locus_tag="J8S10_001074"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HAZ9629672.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            complement(44331..44723)
                     /locus_tag="J8S10_001075"
     CDS             complement(44331..44723)
                     /locus_tag="J8S10_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAZ9629673.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
BASE COUNT        13301 a         9348 c         7833 g        14452 t
ORIGIN      
        1 ctttatgtct ttttttaata acatatataa taaaaaagaa tctttttatt tacgtataaa
       61 gtggagcata atcattatat tatcattgtt atttttaaca ggaattgctt atttctttta
      121 ttttattttt tctcctgcgg acagcaatca aatgaaagaa ataaaagatt cgtgggtttt
      181 ctatacaaaa gatgatcctg attttaagtt tgacagcaag tacactcgta cgattcctac
      241 cgtggataaa gacgaaacat tcattatgga aacgacactt gaaaaaccgt tggacgaagc
      301 aaatttacta atcaaaggaa accatcaatg gattactgta tatctaggcg aaaagatttt
      361 ataccaacgg aaagattatc aggaagaaag caatcccgga ctctcattgg ctgtgataga
      421 tttaccagca aattatatcg gaaaaaaatt gacccttaca gtctcatctc cttatcagaa
      481 ctatgctgga ctgccaccga aagtttatct aggaacaact ggaccattga ttagttttat
      541 ttattcacaa tcagtgccgc aagtattgac gatgataatc gctgttttta tcgctatagg
      601 gacctttttc tatacgatct acttgatgta taaacaaaaa cgtcttgaat actcacttat
      661 tctcttaagt tgctttgctt tggcattagg atttgaagct gtatcagaag atattttaag
      721 tggtattctt tttgaaccat tcgttcattc ttttttatct catttattta ttatcttaac
      781 gtcagctttc atcatctgct actattggag ccgaatgttt tactataaaa aatggtacgg
      841 aattttttgt acgttccaac ttttgatttt tatcggcgtt ctgctttatg caacttttac
      901 tcctgcagaa cttcctgaat taatgccgat tgctaatatt gctagtgtta taagcacttt
      961 agtcacttca cttgcatgca ttggcgaagc atataagaat aaccgttttt atgtagcttg
     1021 tacaccttgg atcgtcttgg tagccattat ccattgcttg atttacatcc aaacggcatt
     1081 aggtatctat caaacaacga tcaattggtc tacgatttta tatattatca ttctaatcgt
     1141 tattatcagc tacaatctaa tcgatcacat cttaaatacc gacaaagatc ggagacaagt
     1201 agatttctta aaaatcaaaa atgatttgtt ggagcaacat tatgagcagc ttcgacagca
     1261 tatccaagaa gtaaatacac ttcgcctgga atttgtccaa gagatggaga atctgcaaga
     1321 tttaatgcat acggaccaaa caaaagctaa aaactatgtg gaaaagatat tagaagaagc
     1381 aaaaaatttc gaaatgctgt gttctttttg caaccaccag gtgacaaatc ttatcttagc
     1441 gcgttaccag aagttagctg ccaaacggaa tattcagata accttccaag cagatcttcc
     1501 cgaagaactt cctatcaacg atgacgatct ggctcaactt ttgatccacg ctttagagca
     1561 ttcctttaga gaaactcatg ccatcgaaaa tccactgtat cgaaaaattt atttgtcgat
     1621 acacgaacaa gaggaacatt tcgtcatttg ttgcgaacat agtgcacatt acgatacaaa
     1681 cctatttagt cgaggcatca cagaagaatt agatgatcag gaacgttttg acttaatgat
     1741 gatgaaagac gtagcggatc gttacacagg aacactaacg caggaaaaag atactttcat
     1801 tgatcggatc actgttcaac tctctcgaaa ttacccgaat cctgtataaa aaatagcgga
     1861 atccatatat gtggattccg ctatttttta ttttcaataa agtaaggtaa gcaattcttc
     1921 tggttctatc gcaccaaaat atttcttcac atcaatttgg ctgactattt ttgatagaga
     1981 tgctttatca tatttctgtc caaccaattt tttttccacg tcagagatat ctcctagtcc
     2041 gaagaaatcg ccaaagattt ttgcttcttt gatcattcct tctgagacat tcaaatggac
     2101 ttcaatcgaa ccgatagaaa aacgtttttg gcgagagaaa ttgaaatctg gagacttccc
     2161 gtaattccaa tcccaatttc gataatattc ctcagagatt cgattgattt ttttccaatc
     2221 ttcatcagtc aattcgtacg tttttacttc ttctactgac tctacgccga aaattttcaa
     2281 caagatttct tgacgaaatt cttctgttgt cattttttgc ttttcttctg gaagaaatgg
     2341 tttgatattc gttacacgag aacggatcga tttgattcct tttgattcga ttttgtcttt
     2401 ttttactttt aatgcattga ctacttcatt gatatcagag tcgaacataa ttgttccatg
     2461 agcaaacatc cgaccgttgg tagcatacat cgcgttgcca gaaaatttca tgccatcaat
     2521 gactagatca tttcggcctt tcaattccgc cccagcaaca cccaattcat gaagtgcttg
     2581 gatgattggc tgtgttactt tcgcaaagtc acggaatgaa tccccatcat caggcatgat
     2641 aaaactaaag ttcaggtttc caaaatcatg gtagacagct ccgcctccac ttaagcgacg
     2701 gacaacatga atgccatttt cttccacata atctcgattg atttcttcaa gcgtattttg
     2761 gtttctgccg atgatgattg aaggttcatt gatataaaag agcaaaatag gttcatctaa
     2821 aggcatttct tgcagcaaat attgttcaat tgctaaattg attcttgggt cgtggttttc
     2881 atttggtaca aaaatcatgt tcttcctcct aaatgttaaa cactttgtca actgcagcaa
     2941 gttctatatc aatccctttg cctgctgcct tttgcgcttc atttttcaat tgttctaaat
     3001 caccaaactg aggtaggtgt gtaagtacaa gtttctttac gttagctgat ttcgcaagtt
     3061 ctccagcttc ttttgaagtg aaatgggcat gatgatgttc atttccttca aaaagatagg
     3121 tatctgctag aaacaaatca gcatctttcg caaaatcagc gaaactttcc aaataacctg
     3181 aatcacctgt aaatacgaat actttccccg ttgtttcttc tacgatacgc atggcgtaac
     3241 atactactgg atggattgtt tccataaaag taatcagaaa aggaccaatt tttaattctt
     3301 cagcttcaaa ataaggatgt ccttttgaga cattttccaa cgtcaattct tcaaagtgaa
     3361 tggaatcttt tgtgtgtcca taaattgaaa gcaatgtctc cggatttctc ttaggatgaa
     3421 gttgccagta atactgtaat acaccaaggt cagcaatatg atcatgatga taatggctaa
     3481 ggatcacagc atctagatca agtggatcaa ggtgttcttg taatttgatc agcgtagcac
     3541 tacctgcatc gatcaacaaa ttgaacccgt cagattgaag caaataacct gttgtccctt
     3601 gatttttata aggatacgct cctaagcatc ctaaaacagt taatttcatc gtacattccc
     3661 cctcaaagat ttatcctacc acaaaagtta tttttttgat gaataaactg cttacatgct
     3721 aagtaaaata ggcgtctgga cctccttttt caatccgtgc ttgttcataa aattctgcaa
     3781 ctgacacatt cacataaaca atgacccaca aaagaccgat gaacaaagcg attgctccta
     3841 gcaaatacca gccgataaaa gacagctgca acaaaatata cgtaccaatt ctatctttca
     3901 ataaaaacca gccatatttc aaacattgaa taaccgacaa atcaggatag tcgaactttg
     3961 tccatgcagc aaattggaat aaaccgccaa caatactcat gatgagtgct gaaacaaaaa
     4021 tcatccctat catcgataaa acaaagctga tatcaagaaa atcttctggc atgacacccg
     4081 taggtaccgc atttgaactg aaaagcagct gcatataagt actcactccg ctgattaaaa
     4141 acatgggcag aaagattaaa ctgttgagta gccagttgat gactgaattg atcaaattga
     4201 tgccaagtat cgaaccaaaa tactttcttt ggaaaactga aaataaaagg ttactttttg
     4261 gtctgccacc ccgtacaact actagcgcaa tgtaaaacaa tgcatagttg aatgcgaata
     4321 aaagtaaatt atcgactaga aaactcaata agtgctgctg catgctttct tccggaaaag
     4381 gactgaaacc gtcaaaaaag ttctggatga cgctcgtaaa tattatagat aagaaaacaa
     4441 gccaagtatt gattccccat tgattttcca aagaaactcg tgcttttttc cgatattcag
     4501 aaataggtat tctattattc attattcata actccgaatt ttttcaactg tttcactatc
     4561 aagccgtttc actaattctg tgactagttt cactgtattc aaataatcat cttcatgaat
     4621 cactgatgta tgggaatgca gataacgaac aggaacggta atggctacag acggaacacc
     4681 atctcttgtc aaatgcattt gtcctgcatc agttcctccg ccagaaatca ctgtatattg
     4741 gaatggaata tccatttcct ctgctacatc aataacaaaa ttcaataatt ttttatgcgg
     4801 gatcatagat gcatcaaaaa tcaaaatctg tgggcctttt cctaaaatcg aatctgcttc
     4861 ttttggtgtc attcctggag tgtctcctgc tgtaccagta tctaaagcaa aagcaatatc
     4921 gggatttaca aggtgtgtac ttgttcgagc acctcgcaag cctacttctt cttgcacatc
     4981 gcttcctgcg aataaaacat ttgggtgtgc ttctttagat agattctcta atactcgcag
     5041 agaaacagct gtcccgatac gattatccca tgcttttgcc agtaaatatt tactgccatt
     5101 cattcgtttg tattcaatat atggagtgac catatctcca ggacgtatgc cccactcttt
     5161 ggcttcttct tggcttgatg cgccaatatc aatgaacata tcctttattt cataaggttt
     5221 atttcttact tgaggtgtta aaacatgtgg tggtttggaa ccaatcacac cgtggacgat
     5281 tttcccttca cgtgttttga tttcaacttg ctgagcaagc atgacttgcc cccaccaacc
     5341 tccaagagtt tggaattcca agaatccttt ttcggttatt tttgttacca taaaaccaac
     5401 ttcgtccata tgtccagaaa taaagacctt ggggcctccg ccagcaccat gtttggcaat
     5461 cacactgcct aaaccgtcat aaaaaatatc atcagcgaat ggtttggcat attctctgaa
     5521 tacttctctt acctcttctt catttccagg tactcctttt gcagaagtta aatcaataag
     5581 tagctgttct tcttttgtat ccaaatgttt tcccccattt ctatattcat attgtgatta
     5641 taccattgct tatgattttt gttcaggcaa acttggtatt tttatctttt attcagaata
     5701 ttcaaaaata aagaaaacaa gcgagcaaca ctcgcctgtt ttctttattt taattgtagt
     5761 ttatctggta tttgatgttg ccaagatttg ctaaaaaaag catcgtcaag atgatactta
     5821 ctagcagtaa tatgattttc ttctaaaaac ggtctgatct gttgatctgc agccaaccag
     5881 cctttccagc ctagatggat cgtgtcttcc ataaaatagt tggtacccgc ttgattgaca
     5941 aaatcagcta ttcgattgaa tccttggcta tttaattgaa atttgatctt tttggcaaat
     6001 ccttgtaaca tttcttgaga tagtccggta taatcgctcc atttctcgtt aaccggtggg
     6061 atgatgaaca atacttcgtt atggtttttt gctaattgat ccaagaccag ctgaaaatca
     6121 gaaaattctg gcgaaaaacg ataatcccaa tttttttgtg actgtttgag ctctggctcg
     6181 tgggctcgga tacgatgcgt ataaaaatcg tttttcaacc cgaatggatt attcgtcgtt
     6241 tctcgttctc caatttgatt tgctaaaatg gataattctg tttcttggta ttgttttggt
     6301 aatcgttttg actcatgatc gattttttgc tgtcgatctt tcaacccaat attgctgaat
     6361 acttcatcct ctctcttcag catgttccat tggctgcgca gctgattcaa agattcaggt
     6421 aaaggtagct tccctttttt gatcgtttgc agaatcgccg tcaacgtatc attctctttt
     6481 acttttgaga aagttaataa tcttctagct aaatagcgat cagcaggcgt tactttcttc
     6541 attgaaaaca accagtcgta tgtttgaagt tcagaataat acgtattaaa gtaatcagtt
     6601 tttacaccat ttttaacgaa ccactgagga gaaataataa agacgacttt cttgtttttc
     6661 atagcatctc ctgcagaacg catcatcata tattggctta acgattgtgt cccgggtgct
     6721 cccagcaaaa atggacgata gtttcgctgg tatttttctg ccagaacaga cggatgaaat
     6781 ggactgattc tgcttaattc acttgagcca aaaaaaggaa tatattgttt ttcagataat
     6841 gcataatttt ttatcgcatc tcctttcaac acgttcactg acatggaaga agaggcacgt
     6901 ctaatcgttt ctggattaga gatatctact tgataggagg aggtaaaaaa cacaaacagt
     6961 aagccaacag ctaaaacaac cgggccgaaa atagcaaaaa gtttcttttt catactcaac
     7021 ccttcaatgc agttgcttgt tgaatgattt tattcggtgt gcaccaatcc tctcgctcga
     7081 attcagatac agggacttgg atatccagct ctccgtctag ctcgactaat aattgaacag
     7141 atgctaaaga atcaagcaac ccttcatcaa atagatcaat atcacgattt tttcttactt
     7201 catctgttcc tgttatttct tctaagattg ataaaatttg ttcttccatt ttccttttct
     7261 cctttgttat ataaattaat atgtcactat tcgttagcta aaaaaaagtt tatctaaaaa
     7321 tcctgaaaaa atcaggaagc taaaacatac tgcttgaaat gtcaaaaata cggctaagcc
     7381 atgcgtaaat ttgttagaag gcaactgctc tttatgcttc ttcttaaatc ggatccatgc
     7441 atctgtcaga cagatcagac aagcatgata cagtccatat acgatgtagt accacgtcaa
     7501 tccatgccat atacccatta gaagaaacaa agcaaaataa ccgatatttg acattacgat
     7561 cttgctttta aaaaattttt tcttcatcat gaagaacatc aatcgcatat atacataatc
     7621 acggaaccaa aaggacagcg tcatatgcca acgattccag aattctttga tattccatga
     7681 taaaaaaggt ttattgaaat tgattggtgt ctgatatccc atcatgtagc ttgtaccgac
     7741 tgcaaataag ctatagccag caaaatcaaa aaacaaatac atactgtaca cgtacatata
     7801 acctactaat gcccatgaaa taccaccatg ctgtaaggca atgcgtccca ctacaggaag
     7861 cagtacttga ccaaaataat aaccgataat gaatttatat aaaaaaccga caaaaatatt
     7921 ttggacgcct tttcccaaaa gatcaacata tttatcacga acaggcggat ggagctgatc
     7981 tttttcaaat ctcctatagc gatcgattgg tccagaagag attgttggaa agaacagcag
     8041 aaactggata taacgaaatg gcttatatgt tttgatcatg ccatctctta tttccatgat
     8101 catttgtaca gatttaaagg ttaaataaga gattcctaaa aaaccaagta acgatgcttt
     8161 tccatgttca aaaaaaggag tcactttcgt taaaaacagt ggaattatcg ctaaaataac
     8221 ggcggcaaaa aaccatcctg tctgattttt cctttgccga taaacaaaat agccccatac
     8281 aagtatcgtc tgccacaaaa catacccaat cagcgccgct ccctgttgcc aataattacc
     8341 tccaaagctg acaaataaaa agaaaagtgt cactgctgat tgataaactg gtaatctttt
     8401 ttcccatatc aataaagata gaacgatcgg tacaagcgca atggctaaaa gaaaaaaata
     8461 aaacggctct gcataaggga tcatatgagg taacatcatt caggattcac ctcagctgtt
     8521 aatttttttc gatcgatttt tccattaact gtctgaggca gcagatcgac ataatggaac
     8581 ttctgaggaa tcatataatc cattacaact tctagtaatt gttctttgat agatttagtc
     8641 aactgaaaat ccggctgttt cgttttgttt tctaatacga caaaagcaac cagctgctgt
     8701 acttttgttc cttggtattt tggtacgacg acagcttgtt tgattcggtt gtcttggagc
     8761 agataatgtt cgatatcccc gagttcaatc cggtatccat gtaatttgac ctgctgatcc
     8821 atacgtcctt cataaaataa aagcccatat tcatctagtc tacctgcatc ccctgtatgg
     8881 taacttgcta agtcattttg acaaaagaac gcagcagctg tcttttcggg attgttcagg
     8941 taaccttttg atacgcttgg tcctgcaata atgatttcac ccgtttctcc ttttgaaaca
     9001 ggtttacctt cttggacaat agaaactttc gtgtcttttt ttacgtagcc aatcggtagt
     9061 cggtcataac tatctagtac atgctggtca atctgaatac ttgaaatagc tacagttgct
     9121 tctgttggac cgtaagtatt atatatccgt gcatttggga atcgatcaag tagactttct
     9181 gcagtttttt tcgtcaattc ttctccgcaa aataaaaaca tgtccaattc cggcacattt
     9241 tctccattga atgtaggttc catcaagcaa atatccataa atgatggagt agaaacccac
     9301 acattcaact tcaaggctgg caatgtcgcg aataattgac gaaagtcttg aacaactgct
     9361 ttatttaacg gcttcagcat tccgccagaa actaatgcag gataaataga aaataccgat
     9421 aaatcaaaag aaaatggcgc ttgggctaag aaatgcatac caggcttgat cccaaagtct
     9481 tccatcgtcc attgaacaaa gctgactaga ttatcatgac tgatttgtac gccttttggt
     9541 tctccagtag taccagaagt aaaaataata taaaaatttt ctgtaccttt tacgctattt
     9601 ctgggataaa atcctactgg tatcttcttg atttcttgaa attctttttt tgttatgaca
     9661 ggaaccgaag gaatatcttc tatccagtcc ccgatactga tgaccataga tggtttagcc
     9721 acccgaaaga tcgataggat acgctccttg ggtgtatgct cttcaatcgg caaataggca
     9781 tggccagatt tgacaacccc tagaaatgag acaatcattt caaactccaa attgccaaaa
     9841 acgacaattg gtccatcgcc ttctaccttt ttttctaaat aataagcaag tgcgtctgat
     9901 gcttgtttca attcaccaaa agtatgcgtc tcatccgcct gataagcaac tcgatcaggt
     9961 tcatttattc cccaatcatc gattgcttca ataatcgttt tgatttccat actcttcctc
    10021 ctaaaattcg ttatagataa aagttcctcc ttgaatattt ttatagtgat acagataaat
    10081 caggaacagc agtactgcac tataaaaaat tgttcgaatg atgaattttc cccaataatt
    10141 caattttgga ttagaacgcc atttgttcat tggattccct cctcatataa cctcacacaa
    10201 agtgtaacta attttgacaa aaagaaacat gtgtctagct tacagaaacc gtttttttac
    10261 taacagtttt gtcacatagc ttttataaaa atagcacatc aaatcactgc ttttttcttt
    10321 ataatttctc gtacttttaa aaaatataaa aaataaagag gttgtgacaa aaatcgtgtc
    10381 acaacctctt attccaaata aatggtattc aaaatttagt tctatttatt atcttgtctt
    10441 attccgtata tcattcctcg ataatccgac aatataactg actcgtaatg acataaagca
    10501 aaagatagat aaggatcaat aagccactca caagataagc caaccagtaa tcggcagttt
    10561 ttatatactg agtgaagaca ttgattgcaa atactgcgtg agtgatccct aatatcatgg
    10621 gtggaaagaa ggtaagtgcg ttttgctcga agatcatccg tctgatcctt ctttgtggaa
    10681 tccccagctt agtcaatagg tgataatttt ctttttcttc ctctgcttct gctaattgcc
    10741 ggactgtcaa aatactacca gtagcaataa tcacgatcat cccgacaaat agtgtgacaa
    10801 aaatattgat accgattcgc cgattaactg cacgcaattt cgaatagctg gaagagaaat
    10861 tcaaacgaga gctttcttgg ctaaattgtg cttccttcat ttggtcatcc ggaagtttct
    10921 ttgtgctaat ttctccttgt agacttccat ttacgatatc ataagaataa taaacagcat
    10981 tgagccactt tatcgacagg tcattgctca gtcgttcatc tattttttca ttatttccac
    11041 ctgatacatc tacattgact acttgataat ccacaccttt tgctttttca aaaacggtat
    11101 catctacaat cagtacagga cttagatata ccattgtttc gtcacctaat acacttggaa
    11161 gcatttgttg aatcttcaat tcttgattat ctggcagtcc aatactagat ccatataatg
    11221 aaatattccg aaaaagagtt tgcatttgat caagcaaaac agtatgacca ggtgatttca
    11281 aagaaatgtt cggcaaatct ggattaactt ttctgaaggc ttgatattgt gtttccgtga
    11341 tcagattagc agtttgaaac ataggttctt cgagattttg actatagata ctcccaatga
    11401 ctttataatg caaggtgatt tctttagtta tcttctgccc ttcctctgct agaatcggct
    11461 tgattttttt ctctgtctca acatcaaact gatagtccat cggggaggaa actttctcct
    11521 ggtaggataa aatagtagag atactagccg tgccgccaat tgtcattaaa gaaattccga
    11581 gaatgactgt aatcagagaa tttgtacgcc aacttttgag caaatgaact tgcgtgttac
    11641 ccattatcaa aaaattgata ccatagtaat aaatcttcca tttactcaat atgatcaaaa
    11701 ataaccgaaa tgtataacag aaaaacaaat aagtaccgac cacacaaacg aaaaaaatta
    11761 aaaaaggaaa aaagaaaact aatgtatcaa gataatgata actgatcatc catgaagtga
    11821 tttccctaaa atgactagct ccaaaatatc cgctcgttaa aagtagtaac ccgatgactg
    11881 cgagtaatcg gtgccttgtc ctgaagcgca ttgttgaact atctgcttgt tctttttctc
    11941 caaaacttcg aatcattgga tagcgccata ttttccatat tgaatataca gatactgcta
    12001 aaaggatgat gaaaaaagca aataaagtat ctactactga tggaatggag ataaaaaatg
    12061 gactagtaag atccatatcc atcattcgaa ccaaaatcat tgaaaagagt ttggaaaaaa
    12121 taataccgag taatatccca gaaatacagg cgaacaatcc aattatcatg atttctaaca
    12181 catatatacc tgatatctgc agtttattca taccaaaaag ctgatagatg cctatttcct
    12241 tttgccttct attcaagaaa aatcggttgg cactgaatac gaaaaaaagc aaaacaacag
    12301 taatgataaa tccaccaaaa ctcaatccac catctatcga agtatcttga cttgctcttc
    12361 tgactaaaga ttgatcgtag gtcattgcgc tgaaggaata atagatcatt acggataaag
    12421 tcaaactgaa aaaataaaca agatagcctc gtgactgccg aaaaaaactt ttaacggcta
    12481 gtttatacag cattcatttt tcctcctccg ccaatcgtcg cctgcatgtc tattactttc
    12541 tcaaagaact ctcttcttgt ccctcttctg acaacttcag aaaaaatcac accatcttta
    12601 ataaataaaa ttctatcgca gtagcttgct gtatatggat catgggtgac taacagtatc
    12661 gttgcttttt ctttttgatt catggtcttc aagtagttca acaattctgt agccgacttc
    12721 gagtccaaag agccagttgg ttcatctgca aaaatcactt gtggctgaac aacaagtgct
    12781 ctagcagctg caattcgttg tctctgtccg acagaaagtt catcgggata ccgtttgagc
    12841 agttcttcta tattcaacaa ttgagctaca tgtcttactc tcttttccat ttcctcttta
    12901 gtcatccgtt caactgctag gggcaatagg atattgtctt ttgcatttag ggtatcgatc
    12961 aaattgaact cttgaaaaat gaatcctagt ttttttcgac gaaagtcact gagctcactg
    13021 tttttcattt ttgtgatttc ttttccttgg atcgagacac tgcccatcgt aggcaaattg
    13081 atcgtggaca agatattcat cagcgttgtc tttcctgcac cacttgggcc cataatccca
    13141 acaaactcgc cttcttctac tgtgaatgag atattatcta aggctttgac gggagaaagt
    13201 ttgctgccgt agcttttact tagatgtttc acttcgatca tcttttccaa ttcttctcct
    13261 cctctttcat ttttcatttc tatttatttg catagtagca tatctacgaa taatttgctc
    13321 ttatgttttt gtcactttta cttggactga ataaaaaatt ttattcaatt attttattca
    13381 gcaaaattaa atatgcaaaa aacaaatcca ccagctacaa gttttcacct tttttcacaa
    13441 taaaatatac actacatata gtatagaaat ccaattatac agcacattga atactatata
    13501 tagccgatat ttagttgctc cttccccgat tttgttttat gatagacaag aacaatttag
    13561 caggagttga agataatgaa agtaaattat gaagaaaaaa ctgtcgttac tcagcagcca
    13621 gagacatccc agatgaaagt catcaaacgc gatggccgcc atgttgattt cgatgaacaa
    13681 aagatcaatg aagcactgat caaagcagaa aagaaaattc acggctcatt atcaccactt
    13741 acttatgaaa aaattcaaat gattgcagac ttggttgtcc aagaaatcaa aagccggttt
    13801 gctgaaaatg tcaaaatcta tgagattcaa aacatcgtgg aacatatatt actagaaaaa
    13861 aacgaatatg aattagcaga agagtacatc aattatcgta ccaaacgaga ttttgctcgc
    13921 agtaaagcaa cagatatcaa cttttcgatt gaaaagctaa tcaacaagga ccaaactgtc
    13981 gtgaacgaaa acgcaaataa agacagtaat gttttcaata cacagcgaga tctgacagcc
    14041 gggatcgttg gaaaatcaat cggactgaaa atgttgccac cacatatagc aaatgcgcat
    14101 caaaaaggcg atatccatta ccatgatttg gattatcatc cttatacacc gatgacgaat
    14161 tgctgcttga ttgatttcaa aggcatgctg aacaatgggt tcaaaatcgg caatgccgaa
    14221 gtcgaatcgc caaaatctat ccagaccgcc acagcacaaa tctcacagat tattgccaat
    14281 gtagcgtcaa gtcaatatgg tggctgttct gccgaccgaa cagatgaatt gcttgctcct
    14341 tttgcagaat tgaactataa aaaacatcta aaagacgcgg aagaatggat cgattcgcca
    14401 gaacgccaaa aagaatatgc aaaagcaaaa accaaaaaag atatcttcga tgctatgcaa
    14461 agtttggaat atgaaatcaa taccttattt acttcaaatg gacaaactcc tttcacttca
    14521 ttaggatttg gactaggaga aaactggttt gaaagagaaa ttcaaaaagc aattttacag
    14581 attcgaatca atggattagg gagtgaaaag cggacagcta tcttccctaa actgatcttc
    14641 actttgaaaa aaggtgtgaa cttaaaccct gaagatccta attacgacat caaacaacta
    14701 gcattggaat gtgcaacgaa aagaatgtat cctgatattc tgaattacga taaaatcgtt
    14761 gaattaactg gaagtttcaa agtacctatg ggctgtcgtt cattcttgca agggtggaaa
    14821 gacgaaaatg gtcaagaagt aaatgtcgga cgaatgaatt taggtgttgt tacattgaat
    14881 ttgccaagaa tcgcgatcga atcaaaagga gatcagaata aattctggca gttactgtct
    14941 gaccgcttag aaatcatgaa agatgcgctt ctctatcgtg tagaacgttg taaagaagcc
    15001 attccagcaa atgcgccaat tttatatatg tatggtgctt tcgggaaacg tctttcacgt
    15061 accgattctg tcaatgaatt attcaaaaac cgtcgagcta ctgtatcgtt aggctacatt
    15121 ggattgtatg aagttgcttc agctttcttc ggtggcgaat gggaaacaaa cccagaagca
    15181 aaagctttca cacttgatat cgtcaaagaa ttaaaagcta atgcagatgc atggggggat
    15241 gaatatggtt atcatttcag tgtctattca actccaagtg aaagtctaac tgaccgtttc
    15301 tgccgtttgg atacagaaaa attcggcatc atcgaaaata tcacagataa agaatattat
    15361 acaaacagtt tccactatga tgtgcgtaaa aacccaacgc catttgaaaa attggaattt
    15421 gagaaggatt atccaaaata ttgttcaggt ggattcatcc actactgtga ataccctatg
    15481 ctccaacaaa atccgaaagc tttagaagct gtatgggatt ttgcatatga caaaatcggg
    15541 tatcttggta cgaatacgcc aatcgatcat tgctatcaat gtggtttcga aggtgatttc
    15601 aaaccgacag aacgagggtt cgaatgtcca gaatgtggaa atcatgatcc aaaaacatgt
    15661 gatgtagtca aacgtacttg tggctattta ggaaatccgc aagctcgtcc gatggtacat
    15721 ggccgccata aagaaatttc ctcacgtgtg aaacacatga aatgaggttg tgaaaaagct
    15781 gtcctgcatc aagtaataag aatagctaaa caaaaatagt tcctcatatt tttcgtttag
    15841 ttgggcttat tactgcagat gcaagctttt gaacaccgtt tattcagaat aagaggctat
    15901 gacaagtctt ttttcaccac cctctttcga tggctttgta tctttgaacg ccctctatca
    15961 aaataagaac aagctttctt gaacaatgga tttaggtcag tttgttctta tttatgtggt
    16021 cgagtagatt ttatcttcaa tagctatatc tttgaacctt aaatgaaaga agttttttta
    16081 tgagaaatcc aaaaccaaaa gaatggttag caaaagacta cagccaaaac tatattgctg
    16141 actacaaacc gtttaatttt gtcgatggtg aaggtgtccg caacagtctt tacgttagtg
    16201 gctgcttatt tgcctgcgaa ggctgcttca acaaagctgc acaaaatttt cgatatggca
    16261 aaccattcac acctgaatta gaagaacaaa tcatcgctga cttgcgcaac gattacgtgc
    16321 aaggattaac tttacttggt ggcgaacctt ttttgaatac agatgtttgt ctgcaagtcg
    16381 tacgacgtat ccgaaaagag ttcggtacga caaaagatat ctggtcatgg acaggctata
    16441 cctttgatga attgctacaa gattcagaag ataaattaga actcctttcg caaatcgata
    16501 tccttgttga cggacgcttt gaattaagca aacgtgacct aaaactacaa tttcgcggaa
    16561 gtagcaacca gcggatcatt gacgtccaaa aatctttaga atccaatcaa gttgtgattt
    16621 gggaaaaatg tacggatgca acagaaacct atgaacaaat caaaaagcaa gacttgatat
    16681 aaaaacagct ttgggagaga aaacggattt ccggtttcaa ctctcaaagc tgtttttata
    16741 tttcttgatt ttcccataat ggaaggacga tgttttcata agtcatcggg tccagattcg
    16801 tcaaagtaat ccctaacaat cggattcctt tttctactcc caagatttcc tcccatataa
    16861 ggcttgcttg ataaaagagt gcttcttttt tatagatata ttctggcaat gtcactcttt
    16921 tggtcacagt agaatagtcc gtgtacctga ccttcaaaac tactgttttc ccatgttttt
    16981 ggactcttct cagtgcttct tctacttttt cagctagttg gcgcaactga gtcagcactg
    17041 cttcttccgt ttgcaacggc tgcccataag tatgctcttt tcccacagat tttcgctctc
    17101 ttgtaacgtt tactggagaa tcatggattc ctctgacttt acgataaaga gaatagccca
    17161 tttttccaaa atttcgaatc aacatcattt ctgtgcattc atataggtct tttcctgtat
    17221 aaatccctag ctcatgcatt ctaggtacag ttttcttccc taccccatga aatttttcaa
    17281 ttggcaaagc ttttaaaaat ggcacagcgt cttgaggggc aactaccgtg attcctctag
    17341 gtttttgata gtctgatgct aatttggcca aaaacttatt gtaacttact cccgcagaac
    17401 atgttagctg gacactctcc caaatatctg cttggatcat tcgggcgatt ttgatggctg
    17461 acttgcaatt gattttattt tcggtcacat caagatacgc ttcatcgata ctaactggtt
    17521 ccacaatatc tgtataacga tagaatactt cccgtacttg tttggaaata tcgctgtatt
    17581 tatgatggtc gccaggctta aagatggctt gcggacaaag ctcatacgct ttttgtgcac
    17641 tcattgctga atgaattccg aattttcttg cttcataatt tgctgtagtc actactccac
    17701 gcccaccagt gtcactgggg tgtctggcaa ttactaatgg atgtccgcga aactcaggat
    17761 gatctcgttc ttcaaccgaa gcgaaaaaag catccatatc aatatgaatg atttttcttg
    17821 atgtatcatt atgtaaagga aattgcagct ccatcatcct cacctcttat tcattataca
    17881 agaacattcg ttcgcgttca agagatttga aaagttagta gctgatttcc tcattagtct
    17941 ttcattatag acaacttata ctatctcagt ctaattcatg gtactgacgg tagacttctt
    18001 gttttttcag cccatttttc agcgctactg ctttgatagc agcatttggt ttttcgcctg
    18061 aagcgatctt tgcttctact tgttccttta acgttcccaa ctcttcatca acttccgtca
    18121 ctggcatttc gaacaaattc ccttctacaa gcagacaaca ttcacccttt actggatgtt
    18181 cttcgatata agcgagtagc tcttccgtac ttcctctaag gtattcttca tggacctttg
    18241 tcaattcccg acacaaaacg acttggcgat ttccaaaaat ttctaagaaa ttcgtcaatg
    18301 tagcagtgat ccgataaggt gactcataaa aaatcagcgt aactgtctgt tcttttagct
    18361 ttttcaatgt ttctttctgt tcttttttct tacgtggaag gaagccataa aataaaaatg
    18421 gttgaggcac tagccctgaa gcaatcaaag ccgtcatccc agctgtaggt cctgggatag
    18481 agatcacaga aatcccttct tttatgcagg ctaaaactag ctcatgtcca ggatcgctga
    18541 tggaaggcat tcctgcgtca ctgacttgag caatcgtttt tccttctttt aacaaagcaa
    18601 tcaattgagg gacacgttct ttataattat gttcatgtaa acttttttgg ggtgtatgga
    18661 tttcaaaatg attcaataac ttttgtgtat tacgcgtatc ctcacttgcg ataagatcgg
    18721 attcttgcag catacgaaca cttctgtagc tcatatcttc taaatttcca attggcgtcg
    18781 gtacaagata taaatcccca tataccggat ttcccttgaa acttttttga ttatacatct
    18841 gtcacaatct ccttaataaa aagactggag cagtatttct ccgctccagt ctcctcttgt
    18901 tattggtcat cgaccgcttt cgcgatagat cacttctaga caaaacgcac aaggctcgtc
    18961 attgtccctt cttgatccat ataaatcgta gcagacatgg aatccttctt cataaatttt
    19021 ttcaagattc atacgagact tagaaagttc ctgcttcaca ttttcagctg gagcttgtgc
    19081 aacttggttc aattcccgca ggtgttcccg cagacgttga ttttccatct ccaaagttgt
    19141 atttttttct acgatctcat gcaaagcatg cttcatttca acaagttctg ttaatgtatt
    19201 tctcaactct gattctaatt gattcaatcc gtcgtataat gatctcttat ccattcatct
    19261 cacctacttg gataaattct ttcaattcat cccattcata ttcgacagga ttttcccgtc
    19321 cagtcagccg aatactaacg atacggctaa gcagattcaa ccctacgact ttccctttac
    19381 catcaggtgt agcaattact tttccaaagt cagggagttc ttttttcgct gtctcgtatt
    19441 cttcgctctc atattgcaga cagcacatca agcgtccgca taaaccggaa atttttgttg
    19501 gattcaaaga taaactttga tcttttgcca ttttgattga tacaggcacg aaatcgccta
    19561 aaaaagaaga acagcataat ggacgcccac atggaccaat tccgcctatt atctttgctt
    19621 catcgcggac accaatttgt cgaagctcaa tacgagtacg aaatacagcg gccagatctt
    19681 ttaccaattc tctaaagtca attcgcccgt ccgctgtgaa agaaaaaatc aatttatttc
    19741 gatcaaatgt gtattcggct ttgaccattt tcatttccaa ctcacgcaac tgcacttttt
    19801 cttttgcgat tttcaatgca tcataagcat cttttttgtt ttttttgtct ttttctaatt
    19861 cagcttgtga cgctttatgc aagatcggac ggatagcttc aggaaggtca ttgggatcaa
    19921 tctctttttt aggaaggaca acagtagcaa tatgtaagga ttgctgagat tcgactaata
    19981 ccttgtcact ataaacatat tcagagtctc ctggtgcaaa ataatagata tgacctgcat
    20041 ctctatatcg gacacctact acttctacca tttccatcct ccttgatcat catcctttgc
    20101 ggcaagctaa aaaatcgtat gcaaaacgaa ctgttccgca acagcctgaa aactgacatt
    20161 gctgcgtagt ttctgctctg cgatcaatat ccgttcaatt atctggttta tctgtttcac
    20221 tttgccatat tcgccgtttg ctactgcttg acgctgtgct tcctgataat aaaacatcaa
    20281 gacagataat cctgtaaact gttgtgtttt ttctttaaat gattttacca attttttttg
    20341 gacatagata aaggcttgag tatcttgctt ttgcaagtaa acgaaccatt gataaatcaa
    20401 gtccttagca tcattaaacc attcatcttg agagatttca actgcttttc ctaaactgtt
    20461 tgttaagaaa gccaaaagtt ttgctttttc caatggaatc tgctcttctt gcaatcgatg
    20521 gatcagtgct tctttcgaaa gttcttgaaa atgcagaact tgacaacgag attgaatagt
    20581 agggagaatt cttcctactg catctgtttc taacaccgct aaaaaatctc cagggggctc
    20641 ttccaagaat ttcaacaaac tgtttgccgc actgctattc attttttcag cttctttgat
    20701 caaaaaaact ttttttcttg attcgtaacc gctgcgactg aattccgtct gcaaacgtct
    20761 gatctgatcg actttgatgg tttgtccttc cggttcaata accaaaacat ctggatgttc
    20821 tttcttttcg atccgctgac aattgttgca ttttccacaa ggcagattgt ctttcatttg
    20881 ggtacagaac aggtgctgtg caagccatat acctacttca tgttttcctg ttcctttctc
    20941 cccttcaaaa agataagcat gagcgatacg cccatgctca aaactccgtt gaagctgctg
    21001 atacacgatc ggttgcattt gagccaagtt tatttcttga ttcatagctc agctcctcct
    21061 aaaattgatg gaatccttca acaggtaaga cgaagactgt ggcaccgcct acttctactt
    21121 ctactggata agggacgccc ccatccatcg aaatatccag tgtaacaggt gtagatacaa
    21181 attgctttct tgattcacac gtttttttga tgatttccaa tgcttcttct acacggtcat
    21241 cttcaatacc cacgataaac gtactgtttc cagccttaag gaagccgcct gtcgatgata
    21301 gttttgtggc acggatattt gcatcaatca attcatttga taaacggttg ctgtctttgt
    21361 cttggataat cgctaaaata attttcataa acgttcacct tcctagtttt caaaaaattg
    21421 cggatactgt tcaataattg tatgataact tgtttgcagc acttcttcaa agctttttct
    21481 tgcatcaact ttgtggattc tttccggatt ctcttctgcc agctttaagt aagcatgacg
    21541 tacacgctgg tggaattcca aaccttccga atctaaacgg tcgatttgat tttgtctgtt
    21601 tttcttgatt cttcttaatc cggtgtctga atctacgtca agataaaggg taaaatccgg
    21661 cgtagtacct tctgtagcaa actcattcaa ccgagcaatc tcggtaacgc cgatgcgtcg
    21721 gcctgcacct tgataagcaa gagaactgtc gacaaatcta tcgcataaaa cgattttccc
    21781 ttttgccaga gcaggcagaa ccttttcgac tagatgttgt cttcttgctg ctgcataaag
    21841 cagtgcttcc gtacgttcat ccatccgatc attttttgga tcaaggatca ctgctcggat
    21901 ctcttcagca atcggaatgc ctcctggttc tcttgtttga atgatttctg tttttgctac
    21961 ttctttcaaa agagggtaaa gttcattcaa gatgctggtt tttcctgcac catcaggccc
    22021 ctcgattgta ataaatagtc cgttcacatt gttgccccca tctcttgtgc tgcttttata
    22081 ttgtatctga aaaaacactt aattagaaat ttataactca cgtcttcctt cgacagcttt
    22141 caataaagta acttcatctg catactcgat atcagagcct acagacagac catgtgctag
    22201 acgagtcact ttgatacctg cgggtttgat cagacgtgag agatacatag ctgttgcttc
    22261 tccctctgtt gttgcatttg ttgcgataat cacttctttt acatctgcat catgcagccg
    22321 ctgcaacaga gaagaaatat tgatgtcttc tggacctgtc ccttccatcg gtgataacac
    22381 accatggaga acatgataaa gtccgtgata ttctcgcatt ttttccattg ccattacatc
    22441 tttcggctct tcgaccacta ggataacgct tcgatcacgt gaaggatttc tacatatttc
    22501 gcagggatct tcttctgtga tgtttccgca gatactacaa aaatgcaaat cgcgttttac
    22561 acttaacaaa gatttagcaa attcatttac tacttcatct ttcatatcga tcgtataaaa
    22621 ggcgagtctt gtcgctgttt tctgaccgat tcctggaagt ttcatgtagc tgtcgatcag
    22681 tttcgcaatt ggttctggat attgcatatt cattactcct tcagtttaaa actaaaatcc
    22741 tggcaaacct tttgcgtatt tccctaattt tttctcagtt tccacatcaa tttgtgcgat
    22801 cgcatcattg actgccatta cgacaagatc ctgaagcatc tcgatatcat caggatcaac
    22861 gacttcttca ttgatttgga tatctttcat gcgacgatcg cctgtaaaaa ccgctttgac
    22921 caattcattg gtggctttac ctgtaaactc tgttttattt agcagctctt gtgcttctgc
    22981 catttctttt tgcatttttt gtacttgttt catcatgcct tgcatattgc ccattccacg
    23041 catcataatt atctactcct ttttattaat catctaccac tgtaacagct tcggagccaa
    23101 acagttcctc tgcttttact acaagtgttt cttctggtac ttcttgttct tgaggaagca
    23161 actcgatttc tccttctgag tcttcagaag caaaagagtt ttctgttccc tcttcttgtg
    23221 cctgcgtcaa ataatttctt cgaagttctg gccagctttc tcttgtaata taaacaggat
    23281 caggcgcata atctttgatc attcggctta agttgttgtg taccgaaagc tgcaattctt
    23341 cgtcatttgc tgctctttga caaacaatct cataatcaaa cgcaatcact agtcctgtag
    23401 gtccagctgc aactggttcg cttgctttaa gcattgctcg ctgagtgaca gatagactca
    23461 tcagcaagtc ttcccatact tcttttactt ggttcagatg ctgtcttgtc gcttcccgca
    23521 gaactttata tactcgttcc gtcggtacac gataggtact tgtctgtttt ttatgatttg
    23581 tttgctgtac cggctgtact tttgtattct caattcctgt attactgcgt agttccttga
    23641 tttcgtttct tagttcctta atctcttgtt gtagctgttt tactatctga tcatctgcaa
    23701 atgctacatc tgctgaagga acagaagcag acggtagctg tgcaagtttg actgtagcga
    23761 cttccaaata aatagcggca ctattggtaa aacgaatttc attttgagta tcgctcaaaa
    23821 tctttatcat tgaaaacagc tgatccgctg aaacagtttg tgccaattct gtaaatgtac
    23881 ttctgatcgt actcgattgt tcctcaacta ggttaggtgc ttgctgatac atcagcaagt
    23941 cacggcagta ttgtaacata tcctctagaa agcgacgtga ttctttgccg gctgcgagaa
    24001 tttggttcaa tgtttccaat gcttctggta cttctttttt cacgcaagca ctcaagtaac
    24061 tgtccatcat ttcgtcagtt aagctacctg tcacttgcat ggcatcatct aaagtaattg
    24121 ttccttcact aaacgagatt gcctgatcaa gaatactcaa tgcatcccgc atcccgcctt
    24181 ctgcagaacg ggcaatcaca ttcaatgcag ctggttcata gctgatagtc gattctttca
    24241 agataaattc aagatgttcg acaatatctg ccgtattgat ccgtttaaaa tcaaatcgct
    24301 gagtccgtga aatgatcgta gctggtattt tgtgaggttc ggtcgttgct aagatgaata
    24361 tgacactttc ttttggctct tccaatgttt tcaacaaggc attgaaagct cctgttgaaa
    24421 gcatatgtac ctcatcaata atgtacactt tgtacgctgc ctttgtaggc gcataatttg
    24481 cccgatcacg gataaatcgg atttcttcga ctccgttatt gctggcagca tcgatttcga
    24541 tcacatcttc ttgcgtacca gcagtaattg atcgacacat ttcgcattcg ttgcatggct
    24601 caccgtcttt actgttcgga cagttgattg cttttgcgaa aatctttgct gcactcgtct
    24661 ttccggttcc tctgggtcct gtaaacaagt aggcatgtga ggttttgtgg gaaacaatag
    24721 cattttttag tgtctgtgtc acagcttttt gtccaacgat gtcttcgaaa cgctgcgaac
    24781 gccagactcg ataaagtgct tgatatgcca taaggatccc ccttttttaa aaaattcact
    24841 atctcttatt atacgtgata ttaggtaaaa aaactactat ccttctcggc tttttcaggt
    24901 atttaaacaa tacgcaattt tccatttcaa ttccgtctct agtccgagaa gtttcacatc
    24961 ttcctatggt ataataaata aacaataatt gtttggcact agctgaatca gaggaggaat
    25021 tttttatggg tcttatcaaa gcagcaacaa gtatggttgg cggcggtctg gcagatcaat
    25081 ggctagaagt catcgaacca gacaatatga gtgatacaac ggtcatgaca aaaggtgtca
    25141 aagtccgcaa agatgacaaa cgtggctcca atcgtaaagg aacagaagat gttttaacag
    25201 acggaacagt cgtccatgtc tatccaaaca tgatgatgct tttggtcgat ggtggaaaaa
    25261 tcatcgatta taccgctgag gaaggttatt acaccattaa aaatgacgca gctccttcca
    25321 tgttcaatgg aacactgaaa gaagcaattg ctgaaacttt tgaccgattc aaatttggcg
    25381 gcgtcacacc gcagaaacaa caagtttttt atatcaatct ccaagaaata aagggaatca
    25441 aattcggtac aagcgcgccg ttgaactact ttgacaattt ctataacgca gaattattct
    25501 tacgggcaca tggcacttat tctattcatg tcgttgaccc gattttattt tatacaaacg
    25561 caatccctaa aaacaaaaca caagtggaaa tcaatgatat caatgagcag tatttagctg
    25621 aattcctaac agcgctacaa tcagcaatca atcagatgtc tgcagatggt caacggattt
    25681 cttatgtacc atctaagagt ttggaattaa gcaaatacat ggatactgca ttggatgatt
    25741 cttggcgtga attacgtggg atggagattg tttctgtggc tgtagccagc atttcttaca
    25801 ccgatgattc tgtgaaactg atcaatatgc gtaacgaagg ggcgatgcta ggtgatccta
    25861 gcgtacgtga aggctacgtg caaggttcca ttgcacgtgg tatggaagca gccggaaaaa
    25921 atgaagcagg agcaatgacc ggctttatgg gtgtaggtat gggaatgaat gcaaatggtt
    25981 cttatctttc tcaagcagct caaaataacc aagaacaaat caaacaacaa gcagaaaaac
    26041 aaaatcaaca aactgcacaa ggaaatgcgg atacttggac atgtccagtt tgcgggacag
    26101 aaaattccgg aaaattctgt tccaactgcg gagctgccaa acctgtagaa aacgttcagc
    26161 ctaagctaca aatgcgatgc agtgaatgca atgagatcgt ggatctttcc aacggcatcc
    26221 ctaaattctg tccaaactgt ggtaaaccgt ttaaaggaat ccccgttaat taatttattt
    26281 agaaaggtgt gcagctgatg gatgttctta cacataaatg tcctaattgc ggcggtccgt
    26341 tgacttttga tcccaaagac caaaaatttc attgcgaata ctgcctgaat atctatacag
    26401 aagaagaagt cagccaatat gagcaaaagc aaaaagaagc gcgtatggct ggcgaagaaa
    26461 gcaaagaaga accttcacct accgaagatt ttacttttac agcccaagaa cagcttgccg
    26521 atatgaatga agccgagcgc aaagcggttg acgaggcagg cggtttttca gatacagcgg
    26581 acgaatctgc agataatacc gcagcgatag atctttttct ttgtcccaac tgtggtgcag
    26641 agatcgtgac tgatgcgaca actgctgcga cttattgtta ctactgccat aatcccgtcg
    26701 tactatcggg acgtttaagc ggagaattct tgccaaataa agtacttcct tttgctgtcg
    26761 agaaagaaga agcaatcaac agatttctcg cttggaccaa gaaaaaatgg tttgttccca
    26821 aagctttttt caataaggat caaatcgata agttgacagg tgtgtatttc ccttattggg
    26881 ctacagatgc tgaagtagat ggtgccatgc aggcgaatgg tacagttatc cgcatatggc
    26941 ggataggtga catcgaatac acagaaacga agcaatttgc tgtttcaaga gcaggcaagc
    27001 tttcttttaa agaactagta aaaaatgcct tatcaaaaaa tacgcaacaa aagatggtcg
    27061 aaggcgtgca acctttcccg ttagataaag caattgattt taaaagccag tatttagccg
    27121 ggttccaagc agaaaaaaga gatatcgaat atgaggcaat caaatcacag attcaatctg
    27181 aattaaaaga ctattcagag aagctgttaa aagataccgc aaatggatat acaacattga
    27241 ccggtgtgcg aacttctgct tcaatcacaa acgaagtaaa taattacgta ttactgccgg
    27301 tatggcttgt tacttatcga agcaatgact caagtaaaaa agtctactac tacgcaatga
    27361 atggacaaac aggaaaggtc agcggtgtcc tgccgatcag ccagaaaaaa ttgggactga
    27421 ccgctcttgg gattttcgct gggctagcga tcctctttct gatcggaggt tacttgatat
    27481 gatgaaaaaa ttttttttat tctttctttt gctagtaagt gttggctggc cggtggctac
    27541 tcatgcagat acagctacgg taaatgatga ggctgggtta ttcacaacag atcaaatcca
    27601 atctttggaa caacaggcag aaaagctgaa tgaaaaaatc aaaggacgag tcttgatcgt
    27661 aacgactaca tctaattcag aagaaccaag agactttgct gataattact taagagacgc
    27721 agtcggaaat gatcaaaatg gctcagtatt gctattagat atgggacagc gtgaaatcta
    27781 catttcgact tctggtaata tgatcgatta tttgactgat agcagaatcg attcgatctt
    27841 agatgatgtt tatgatcaga tgacaaatgc tgcctattac aatgctgcaa aagcttacct
    27901 gtctaaatca gcaacatatg tggaagacgg agttccagga ggacattatc gtgtagacga
    27961 agaaactggc aaaattacac gctataaggt tttgacgaca gtagaaatca tcattgctgt
    28021 tgttttggct cttatcctta gtcttgtctt ttattttgtg actgtttcgc gttatcaatt
    28081 gaaatcaggc atctacaaat atccattccg agaaaaatcc agtatcaaat taactgaaaa
    28141 aaccgatcgt ctgacaaatt cttttgtcac gacaagaaga atccccaaaa gcccacctcc
    28201 tggaagcggc ggtggcggaa gtactaccca ttctagcggt ggcgggactt ttggcggtgg
    28261 cggcagaagt ttctaaaaat tgctaaatga atgttcgcaa aaaaagggct gtgacaaaaa
    28321 tcgtgtcaca gccccttttg ttgcaaataa acggcgttca aaagcttaca tctacggtga
    28381 taagtccagc caagttaaaa acataagaga ctgtttttac ttggctcttc ttattacttg
    28441 atgcagaaca gctttttcac aacctcttgg taaacggtgt tctcctacca actcctcggt
    28501 cacaagtcac aatattcatc aaacatgaaa agctgttttt tgaaattgtt ccttgtgact
    28561 cagagttaaa cggcaggctc acaacctctt ggtaaacggt gttcaatcag ctgaccctcg
    28621 gtattagctc aaaaaacggc aaaatatgag gaactatttt tccgtttgtt tctctaatac
    28681 tcaggtcaaa acgctgattt cacaacctct ttgttcatca aaagataata ttgtcttcta
    28741 acaagtccat attcaaaata acgatatgat ggtctttaac ggtgataata ccatcttttt
    28801 tcagttgttt taaaattctg tttacactgc tagcagttga gatgccacaa aatttggcga
    28861 tttcttcatt cgtgatcgaa aaatcgatca gcatcccttc ttctgtccgc acaccgaata
    28921 aatcatataa ttcgtaaagt tgcgtacaaa cagctcccag ctttccgttt aatagcattt
    28981 gctgcatttt tttcatcgaa taaagcagac gatagcggta atactctttt acatagtgtt
    29041 gtagctttgg gtcttggttg atattttgcc aaaagcgcac acgattgatt cgataaaact
    29101 ctgcatattc tgattcaact cgaatattat acggcgaatc gatgaattgt gaatattcgt
    29161 cttttaaaag agagacgatt tcaagatctt tgatatagcg aaggttaaat tctctcccat
    29221 catttgaaat aacacttgct tttaccgttc cctctttcaa gatatacgta tgggaatctt
    29281 ccatcccttc gaatgtcaaa tatttatgat atcctttgcg tataatcgga aaatcatttt
    29341 tatccaaata ttcctttaag actctactat ccaatgatgc tcccccatcc aaactttcat
    29401 ctaaaaagat catacagtac tttaaaactt tttaaagtcc aaaggtattt tactaatgat
    29461 attaacattt gttaagtacc tttttccatc acttatgcga tttttttcct tttttttatt
    29521 cgttatactg cagaagtaaa attttttaag aatagaggga aaaaacatga attactggat
    29581 gaacacaatc attaatcgat tagaaacagc atatcaaaca agatttgata tgaaagcttc
    29641 tttagtcttt ttaaatgatg cgtatcaaaa ctcgatcgaa ttgatcaaag cagtggatga
    29701 gaatccaaca aacgaatgcg aagaattttt aaatctgttt atgtctacaa gagatttatt
    29761 tattcgccaa cttgttgatc gctatccatc caattatcac gatgtagaag ttcaaataca
    29821 aaaattaaaa gcatattcag cttaagggga atgtataaca tacatggaaa agaaattatt
    29881 taataaatat tttattggaa tcacattgat caattttatt gtctacctga tttattatct
    29941 gttgatggtc atcatggcag tcattgcgca agacacctta cacgccagct tgagccaagc
    30001 aggttttgct tctgggatct atatcatcgg aacattgctg gcacgcttat tcatggggaa
    30061 acagttagaa ctatttggtc ggaagtttac cttaagaggc ggcgcgatct tctatctcct
    30121 ttcaacatta gcatatcttt atacgccaac tatcggggca ttgtatttag ttcgattctt
    30181 gaatggattc ggctacggta cagtttctac agctacaaat gctatcgtta ctgcatatat
    30241 ccctgcatct aaaaaagggg aaggcatcaa ttattatgga ttaagtacta gtttagctgc
    30301 cgctgttggg ccatttttag gaatgatttt gctgaatatg actgattttc gtttcattat
    30361 ctggttttca attgtactgg tcttctttgt tacgattgcc tgccttgtct ttcctgtaaa
    30421 aaatattcca ttatctgaag aacaaaaaat atctcttcgc tcatggaata tcaatagttt
    30481 tattgaaaag aaagcacttt tcattacagg aattgccttt ttgatgggtc tttcttattc
    30541 aagtgtttta tcatttttat cttcttatac aaaagtaatc cacttagttg ctgctgggtc
    30601 atttttcttc gtcgtatatg ctttggtcat cacatttaca cgtccattga ctggaaggat
    30661 tttcgatgtc aaaggagaac aatacgtgat gtatcctagc tatttattct taacagcagg
    30721 attattttta ctgagtgtaa cgacgaatag tgtgacattg cttatctctg gagcattagt
    30781 cggcctaggt tatggtacgt ttatgtcaaa tggacaggct gtttgtttaa aaatcgtccg
    30841 cgaacatcga atcagtattg ctttatctac ctactttatt ggtttagacc taggcttagg
    30901 cgttggtcct tatttgatgg ggatgctaaa atctcttact tcatttagag gattgtatgt
    30961 gattgccgga gtcattccat tgatatgtac agcactctat cttgttaatg gccgaaaaca
    31021 tagtcatgaa gcagagggcg aattgattga atcattgaaa aatgaaattt gatcttgatg
    31081 aatagataaa aaaaaccgtt cagatctgaa aataatctga gcggtttttt gagtaaaaat
    31141 agtttatgat tattcttaat taaacatcta tttattttta aagctttcat ttatcgataa
    31201 gaatagttta actgttgatt tattccattt tccgttcatc tggtacgatg ccttgactta
    31261 gcaaccactt gtggaagaac cattctgcca caccgatcaa tagagcagga atcaatactt
    31321 tcatccaaat atcgactgta tcattcataa aatatagata gagccacaag ataactgcag
    31381 ctgaaccagc atctgcgatc gtcgctgcga tgttccctac tttacgtaag atcaacagat
    31441 cccctagcac atagatcatg actacaataa ttaccccaac aatcgttgaa tccataaagc
    31501 taacaccgta taaacctgtc agcacgaccc acagaatcgc ccagatcatg attgccttca
    31561 ctaccaacgc cttcacatgt ttcattttct gcactccttt ctcctggata aaaaagtaag
    31621 attatctaac aagataacct tttcattatt ataccatcgg ctgagagaag cgagcaaaga
    31681 taaggtccta tctaaaaatg aggaagccac ttagaacatt cacgtaataa tttatccgta
    31741 cagacattcg atatggtgtt cctttacttt cgcatactgt tcttttgtca gttctttact
    31801 tgtcaccaga taatcgattt catgaaaagc aatggcttga tgcatgaatt tatgtgcaat
    31861 tttttgctgt gtaactaaaa cggcaagccg gtctgattgt tttctaaaag cttttttgac
    31921 cattgcctct ccttcatgag tttctgttac tccttggctg aaatctagcc cgcgacaact
    31981 cattatcgct aaatccgcat aatatgacaa tgcatcgtta taggcttttg aaccgttgat
    32041 tgttgctcgt ttcggaacaa ttgcccctcc caatacagat acttttgccg ttgtatattc
    32101 actcaacata gcagctgtga cgatgccatt cgtaatgatc tgcaaaccat caaatcttgc
    32161 taggtttctg actaagtgta aagaggttgt actggaatcc aagaataaga ccatatcatc
    32221 tcgaatcaaa gaagaagctg tatctgcaat cttacgtttt tctgtttctt cttctaattt
    32281 ggtgatcttc atcaggtaag gcacgtcaat ttttcgattg tcaataagca tggcgccacc
    32341 gcgaactcta cggatcaatc cacttttttc cagaaaaaca aggtcacgtt taatcgtggc
    32401 ttcgctataa tttactaact cgatcaaatc ggtgactctt gcaaattggt tgttttttag
    32461 ataattcaca atctcctgct gtctattctc cacttcattc aacataaaat caccccattt
    32521 actttatata gtaacaggaa aaaagaggtt gtgacagaag tgattggctt cgagaaataa
    32581 gaagaaattt ttcgaaaaaa ctacttctga acatcgtgtg tggttaagag ggtatgacaa
    32641 gactattgtc ataccctctt gaccacacat ttttattttt agtataaact agccttgcct
    32701 actgtgttca aaatttccat tttatgtttg accacttctt gtaccttttt attagctgct
    32761 ggataaattg cattcggctc gtacatcgat ggattttcac tcaatatttc tctcaaagca
    32821 ttgaaaaaga cgcttttaag atctgagctc aaattcactt tggcaactcc gtattttact
    32881 gcttcgctga cttctgcgtc cggattacct gaaccgccat gtaaaacaaa tggaagatcg
    32941 atttgttggt tcaattcttt cagtaagtcg atatttaatt ttggagttct gtttttcgga
    33001 tacaagccat gcgctgttcc aattgctaca gcaagtgtat cgattcctgt ttctttcaca
    33061 aaaatcttcg cttgatcagg atctgtataa atgattgttt cagcacctcc ttcagcagaa
    33121 ccattattcc caatcgttcc aagctcagcc tccactgaga catttaccgc atgagctaac
    33181 gcaaccactt ttttcgtaat ctgtacattg tcgtcgaatg atttcaaaga cgcatcgatc
    33241 atcacggaag aatagccgtt tcgaatcgcc cgtaagacat cttctatcgt accgccatga
    33301 tccaagtgga taacgatcgg cagtttactt gtataagcat aggctcttac tgccgcaaca
    33361 aactcatcac ttaaataggc gatttcatca ggatgaattt ctaagattac tggtgcttct
    33421 aatctctctg cttcttcgat gattgctttc atcatatcat agctgcaaat attgaaggct
    33481 ggtactgcaa attgattctc tttagccact ttcaataact ctttcattgt atataacatt
    33541 acgcttccac ctcatttgtt agattttcat ttttcgtcca cttgtcttgt tttttctctt
    33601 tcactgtttt tttcaatagt ccaagcataa aggctgtagt gactgtacct gatgcaattg
    33661 ccaagacata cataggtaaa ttgttcataa catttggaat tagcatcacc caaatccctc
    33721 catgaggtgc cattgaagta actcctactg ccatggaaat ccctgcagcg actgctgaac
    33781 ctgtcatcaa actaggtatc acgcggatcg ggtcagatac cgcaaacggt atagcacctt
    33841 ctgtaatata cgaagcgcct aaaatccagc atgattgacc tgaagtccgt tcttctttgg
    33901 taaatttatg tttgaataat aaagtggcta aagcaatacc taggggaggt gtcattcctg
    33961 cagccataca agcagcaatc ggtgcattta ctccagctga catcaaaccg atcgagaaag
    34021 tcgaagtcga tttattgatc ggcccaccca tatcagctgc catcatgatc ccgataagta
    34081 atccgaacaa tagcccggat gtatttccca agctattcag ccaatttgtc aaagcatcca
    34141 acacccatgt gatcggttgt tcaatcacaa ataccatcaa aagcccaata attaagatcg
    34201 ataaaaaggg gacgacaatc agctgataaa tagcagaaaa ttcttttttt acgctaattt
    34261 tatttgccag aaaatcacag atataccctg ctagcacgcc accaatcatt ccgccaagaa
    34321 aacctgaacc acctgtagag gccagtaatc cggcaacaat tcctggggca aaacctgctt
    34381 ttccagcaat cgatgtagca atccccgcgc ctaacgcagg aaccatcatg gcaaacgctg
    34441 tatctcctcc gatccttgaa aatgcagctg ctaacacatt atagtctgct gagttgggat
    34501 cagccgctgt aatcccaaag gcaaaactca gtgcgatgat gattccgcct gcgatcacaa
    34561 atggaagcat gtaattcaca ccattcatga aatgattata gattgtcggc tttttctcat
    34621 ttgcagctgg ttctttttca ttagacacaa cgaatacgcc aatatctctc aatgcttcgt
    34681 ctattactac ttgcggttct ttgattgctc ggcttgtaga gacacgcttt acttttttcc
    34741 cggcaaatcg gtccaattcg atttctttat ctactgcaag aatgattgca tctgcctctt
    34801 tgatttcttg ttcagataac tgattttctg tttttacacc ttgtgtttcg aattttgctt
    34861 gatggtttag atttcttgct gttacttcta atttttctgc cgacatataa gtatgagcaa
    34921 ttccagtcgg gcaagcagtt acaccaacga ttttcatgat tattttcctc ctttttcttc
    34981 actatcgata ctcggacaaa gactctacta ttttcattct tgactaatct gtctgatgat
    35041 atctgctggc gtagtggctt cttttattcc ctttctaaaa tctgcattca tcaatcgtct
    35101 ggagagtgtg ctgagaatct ctagatgcat atctgctgat ttttcaggaa ctacgatggc
    35161 aaaaatatat tcaattggca tttcatctat cccgctatag tccgttaatt tggctgtatg
    35221 aaaaaaacac agtgctggtt ttgtcacata tttgcttttt gcatggggaa tcccaaatcc
    35281 atcttctatt cctgtggaga tctcctcctc tcgtttgaat agtgccttaa cgactttttg
    35341 aacatttctt accttatttg tttttttcaa cacatcccct attcgctcaa ataatgatcc
    35401 ttttgaatct atcgatggat cgaaaacaat cagttcttct gcgatcaatt gatcaaacct
    35461 cataaaaaac ctctccccca caaaaaatgt taacgttttc ttggaactga ggtcagtata
    35521 gcatcgctag ctgtaccgtt caatattatg aatgaacaga ggaaaaagac ccatcatccg
    35581 cgtgtataag tcattaaaat gaacgatcta gctcacaaac aatcgcaagt ctataacaaa
    35641 acaaaaagcc ttccttgaaa ggaaagctta gcttctaatt ttaggtaaat ggttttttac
    35701 ttcgaaataa cccctcttca tttcgttaat ataaggtgtt tttatcaagt ggataattaa
    35761 aactatatac tagtttttca ttgttttgtg cattatgatc ctacgacttt ttcagcatca
    35821 aacgaagttt taaattggca aaaaacataa aaaaacagac tatccctatc agatagtctg
    35881 ctaaacgttg agttatcagc gtttttatta ttccgcagcg tttgcgtctt tgagaccgta
    35941 ttttttgttg aaacggtcca cacgtccgtc tgcttgtgtg aatttttgac gtccagtgta
    36001 gaatggatgt gagtcagaag ttacttcgac acggatgact gggtatgtat taccgtcttc
    36061 ccattcaact gtttcttgtg aagtttttgt tgaacctgac aagaatttga aaccagttgt
    36121 tgaatccatg aatactactg ggtggtaatc tggatggatg ttttctttca tgattttttc
    36181 gctcctttgc cctgctccat ttgctgaacc agagttgatt tgtcgattta caacattaac
    36241 atcttaacat gtttcagtca aggttgcaat tatcttttca gatttctggt cggatttttt
    36301 ttaccaaagg agacatcttg aaattctttg aaaaattgct gattgttttt tgttttacgc
    36361 aaaaagcgga tcagttgttc cgtatattct aatgaatctc cagtcatatt ttttcgaagt
    36421 ttccaaattt cttctaattc ttcacttggc atcaataatt cttcttttcg ggtacctgat
    36481 tttttgatat cgatggctgg gaagatccga cgttcagata attcacgtga aagttgtaat
    36541 tctagatttc cagttccttt gaattcttca tagatcacgt catccatacg gcttcctgta
    36601 tcgactaaag cggtcgctaa aatcgtcaaa ctgccacctt cttcgatgtt tcttgctgcc
    36661 ccgaaaaatt tcttaggttt atacaatgcg gctgggtcaa tcccgccact caatgtacgt
    36721 ccgcttggtg gaacgactaa gttataggcc cgagcaagtc tagtaatact atccatcaag
    36781 ataacgacat ctcgtttatc ttcgactaaa cgcattgcgc gttccaatac taattcagaa
    36841 actcgagtat ggttttgcgg ctgcagatca aatgtagaag ataccacgtc gcctttcacg
    36901 cttcgttcta gatccgttac ttcttccggt cgttcatcaa tcagtagaac gattaattct
    36961 acttccggat agttttcggt gataccattt gcgatttctt ttaatacaga agttttccct
    37021 gcttttggcg gtgcgacgat caatccacgc tgaccaaaac cgattggaga aaagatatcg
    37081 atcattcggg tagatagtct ttgcggtgtt gtttccagtt gaagctgtct ttgcggataa
    37141 agaggtgtta aggctggaaa atgcggacgt tcttttgctt cttccggatc ttttccatta
    37201 acgctttcca cgtgcatcaa accataataa cgttccgatt ctttaggtgg acgggctttt
    37261 cctgccactt tgtccccatt tctcaaactg aatcgtctga tttgtgaggc agaaatatag
    37321 atatcttctg cacttggtcc ataattgatt ggccgtaaaa aaccgtaacc atcttgacca
    37381 acgatatcca atattccttc catataataa aatccttgtt tctctgcttg tgcacgaatc
    37441 acagctagag ataattcctt tttattcatc ttactgtaat aaggaatttt aaattctttg
    37501 gcataactat aaacttcttt taacgttttg ttctctagtt ctgccattgt caaataatcg
    37561 ctcattcagc tcccacttcc tctatcattt caattgatgc ccctaaggct gttagtttct
    37621 cgataatatg atcataaccg cgtaagatat aatctacatt gtaaatcgtc gttgtccctt
    37681 ctgccaatag tccagcaatc actaaacaag cacctgcccg aagatcagaa gccacgactt
    37741 ctgtgccgtg aagtttattt ggaccattca cgatgatcat atttccttcc acggtaatat
    37801 cagcgcccat tcgtgctagt tccggcacat ggttcacacg tttcgcatag atcgtatcga
    37861 tgatttctga agtgcctgta gtcatcaata gtaacgcagt aagtggctgc tgcagatctg
    37921 tggcaaatcc tggataagga taggtcatga tgtttgcggg ttttaattct ttcgaggggt
    37981 aaacttcgat ttcatcttcg ctgattttca tatggacacc aatttcctgc aattttgcta
    38041 taaagctttc caaatgttca aagatcacat ttttcacttt gataccattt cctactgcag
    38101 ctgctaatgc tagataggtt cctgcttcga tgcggtcagg aatcatgaaa tgccgacagc
    38161 catgtaatgt ttcgactcct tcgatacgga tcacatctgt acccgctcct cgaacttttg
    38221 cccccatatt attcagtaaa gttgccacat ctatgatttc cggttctcgt gcagcgtttt
    38281 caattactgt ctgtcctttt gcttttacag cagctaacat cacattgatc gttgctccga
    38341 ctgaaaccac gtccatgaaa atccgattgc cacgcaatcc tttattttct gtccgtaaat
    38401 acatggcacc atgttcattt gtcacttcag cacctagagc ttcaaatcct ttgacgtgta
    38461 ggtcaatcgg tctagggcct aaataacagc cacctggcag gcctactacc gcttcgccaa
    38521 atttaccaag cagtgttccc ataaaataat aagaagcacg caaactattg atttttccgt
    38581 gcggcatcgg aatcgatacg acttctcgag gatcgatttc tagtatgttg ttggaaaaat
    38641 ggacagttgc gcccatgatc tctaaaattt caattaatga atgaacatct tgtatgtccg
    38701 gcacaccttc caagatcact ggggaatcag ctaagattgc agctggaatc aatgcgactg
    38761 cactattttt tgcaccgctg atcgttactt caccagctaa aggtcggttt cctttgatta
    38821 cgattttttt catctgtttc caccttgttt attaatcttt tttcatggat atgcttgtat
    38881 tttatcatag ataaaaaaaa agaaacaagc atggtctgcc gttttaagta aaaaagaatg
    38941 gagagcgact tcaaaagtcg ttctccattc ctatatatcg tatctgttat gtggatgctt
    39001 acgctttgtt agctgaaccg aaccagtcga tatgagattt agcatcttca acgattgctg
    39061 ctttacctgg agctaataat ttacgagggt cgaatccttt accttcttta tctttaccag
    39121 cttcgatata tttacgagta gctgcagcaa atgataattg gaattcagtg ttaacattta
    39181 cttttgagat acccattgag atagcttttt cgatttgatc ttgaggaata cctgatccgc
    39241 catgtaatac taaaggcatg tctggaccta cagcatcagc aattgcttgt aagtggtcaa
    39301 aagctaatcc tttccagttt tctggatatt gaccatggat gttaccgata ccgcaagcta
    39361 agtagtcgat acctgtagca accatttgtt tgcattcttc aatatcagct aattcgccgt
    39421 taccgatgat tccgtcttct tctccgccga ttgaaccaac ttcacattca actgagatac
    39481 cttttgcatg tgctttttca acaacgtctt tagctaattt caagttttct tcaaatggta
    39541 gatgtgaacc atcgaacatt actgaagtat agcctaattc gatacattcc aaagcagctt
    39601 cgtaatcacc atggtctaag tggatagcaa ctggaacagt gatgttcatt gcttcaacta
    39661 aatcagtgat taaatcttta cagattttgt aaccacccat gtatttagct gcacccattg
    39721 atgtttggat aagtactggt gcttgttttg cttcagccgc ttcaaggatt gcttgagtcc
    39781 attccaagtt gtttgtgttg aatccgccga cagcgtaacc gcctttacga gcagctttta
    39841 aaaattcagc tcctgatact actggcataa taaaattcct cctaagtttt gtaaaactaa
    39901 atttgttaag acaattctta accaacgacc ctattttacc aaacatttcg gtagttttct
    39961 actaaaatca atgaaaatga aaattttcaa gaagtttttt gcaaaaaata aaatatccaa
    40021 tagcgcttta atcgaaaaaa gtcttttgct ttctatcttt tttcctacaa ataataacaa
    40081 atcagaaaaa gagaaaagtg acaagaaaat tgcttatccc cttctcttgc tacttttctc
    40141 tttctatcaa gttcaaaaat tattttgttt cgtgatctgc taatgatgct ccgacaaatg
    40201 ctttgattaa tttttgcggg cgatttggac gagaaatcaa ttctgggtgg aattggcatc
    40261 ccacaaagaa ttttttctct ggcagctcta cgatttctac taaacggtta tctggtgaga
    40321 cacctgaaaa gactagccct tgttcttcaa acaattgacg atatttgtta ttgaactcat
    40381 agcggtgacg gtgacgttct tgcacaacat cggctccatc atatgcttca gccgtcttcg
    40441 ttcctttttt gattttacat gggtataatc caaggcgtaa agttccaccc aaattctcga
    40501 tgttttcctg atcagccatt aaatcaataa tattgtttgc tgtatctgga ttcgtttcag
    40561 ctgatgacgc atcttctaat ccaacgacgt tacgtgcaaa ttcgacacaa gccatctgca
    40621 taccaagaca aatacctaaa aacggaacgt cattttcgcg agcataacga atcgcttcga
    40681 ttttcccttc tactccgcga tcaccaaatc caccaggaac caagattcca tctgcgtctt
    40741 tcaaacgttc ttctacattt tctctcgtta attcttgtgc tttgatccaa tcgatctcga
    40801 tgtctgaatt ataggcgaaa ccagaatgtt tcaatgcttc aactactgag atatatgcat
    40861 ctggtaactc gacatattta ccgacaagcg caatccgtac ttttttcttc aagttcaaga
    40921 cacgttcttc taattctttc cattctgtca tgtctgcttc tggtgtatct agttttaaat
    40981 ggtcgcaaac aatttgatcc attccttgtg cttgtaaaac taatgggatg gagtaaagtg
    41041 tatctacatc tggcgactcg ataactgctt ctggttcgac atcacaaaat tgtgccaatt
    41101 tgtttttcac gctttgagaa acaggttgct ctgtacgtac caccaaaata ttcggttgga
    41161 tacctaaacc acgtagctct tttacactgt gctgcgttgg tttagttttc atttctccag
    41221 cagctttcaa gtaaggaatc aatgttgtat ggatatacat aacattatct gtaccgacat
    41281 ctgctttcat ttgacgaagt gcttcaagga atggcaaaga ttctatatcc cctactgttc
    41341 cccctacttc tgtaatgatc acatctgaat cagtcatttt agctgctcgc atgatttttt
    41401 ctttgatctc atttgtaata tgaggaataa cttgaacagt tgctcccaag tattcgccct
    41461 tacgttcttt acgcaaaact tcagaataga tttttcctgt cgtcacgttg gagtatttgt
    41521 tcaaattgat gtcaataaaa cgttcgtagt ggcccagatc caaatctgtt tcagcaccat
    41581 catctgttac gaatacttct ccgtgctgat atgggctcat cgtccccgga tccacgttga
    41641 tgtatggatc aaatttttgg atagttactt ttaagccgcg gtttttcaat aagcgtccta
    41701 aagaagctgc aacaatccct tttccgattg atgaaacgac accgccggtc acaaaaatat
    41761 attttgtcat aagttcaaaa actccttttt aatttatgtg caggaaaagt ctcagacaat
    41821 aaacaaagct ccctattctt caataagaat agggagccga aatttctgta aacttctgac
    41881 cctctaaaag ggtgcccaag gtgtataata caagctgact aagggaaagt caagtactca
    41941 aatgaatact atccgcttac aattttttct ttttcgatat cctttgagaa attatttctt
    42001 aagtccttta tgagtgcaaa aaaaatttaa cccacataat aagcttgata taaacatagc
    42061 taacgttaaa cctaagcaaa tcagaaaatc gttactgaaa aattttaagt gaaataatag
    42121 ataaaaaaat aaaacaaaca ttatgataga taatatccca cctaacaaag aactactttt
    42181 tcctacttgc agcaacagtt tatatagctt atcgtagaaa caatcttttt ctttcaccct
    42241 tatttacctc ctttacgtaa aaaacgtagt ccacagttct cggatttttg gcatatcttt
    42301 tctattaaat aatatcaaaa acaaaacaat tccactaatt ttttcaaaga tgaccttttt
    42361 ttcaacaaaa gtgccttgta gggattcatt gaaggtaacg aatcacataa gtaaaaaata
    42421 aggagatgcg acaaaagtcg tgcctcctta tttctaaata aacggtgttc tcctgccaac
    42481 tcctcggtca caagtcacaa tatccatcaa acatgagaag ctgtttttga aattatttct
    42541 tgtgattcgg agttaaatgg taggctcaca acctctggat aaacggtatt caaaagccag
    42601 tttctcggta ttaagccaaa tttatgcaaa aatgtagaaa gccattttca caaaattttt
    42661 cttaatactc gaaactaaac gtctttttca aaacctcttg gtaaacggtg ttcaaaagct
    42721 tgcatctgcg gtaataagtt cagccaattc aaaaacaaga aaagctgttt ttgcttggct
    42781 attcttatta cttgttgcag ggcagctttt tcacaacctc tccactaaac ggtgttcaat
    42841 cagctgaccc tcggtattag ctcaaaaaac ggcaaaatat gaggaactat ttttccgtta
    42901 gtttctctaa tactcaggtc aaaacgctga tttcacagcc tctaattcac ggtattcctg
    42961 ttttaataaa gttctagata ttgttctctt tcccactcgg aaacagtttg tctgaatgcc
    43021 gcccattcga gacgttttgc ttcaacaaaa tttgagaaga tatgttgtcc taatgcgtca
    43081 atcattacat tatccttacg caattctttg atagcattat ggatagttga aggtaagtcc
    43141 tggatatgtg cagcttctct ttcttcctca tccattacat aaatgttacg gtcaacagct
    43201 gctggcggtg tgatctgatt acggataccg tctagtcctg cttgcaacaa tactgccatt
    43261 gccaagtatg ggtttgcaga tggatcaact gaccgcaatt ccaaacgtgt ggataaaccg
    43321 cgagattctg gtacacgtac taatggcgaa cgattacggc cactccatgc gacataaaca
    43381 ggcgcttcat aacctggaac gagacgttta taagaattga ctgttggatt gcaaacggct
    43441 gtgtaggcac gagcatgttt cagcaaacca cctaagaaat gataagctgt ttcacttagt
    43501 tccaattcac cgtctttatc atagaaaaca tttccttcat cattgaacaa agacatattg
    43561 caatgcatac cagaaccatt gatcccaaat aacggtttcg gcatgaaagt cgcgtgaagt
    43621 ccatgcttgc gtgcaatcgt tttgacaacg agcttgaagg tttggatatt atcacaagca
    43681 tctaccacat ctgcatattt aaagtcaatt tcatgctgtc ctggcgctac ttcatgatgt
    43741 gaagcttcca cttcaaagcc tagactttct aattccaaca cgatgtcacg gcggcaattt
    43801 tcacctaaat ctgttggtgc aaaatcaaaa taaccacctt tatcattcaa ggtcgttgtg
    43861 atcccaccgt cttcgtctaa tttaaataag aagaattctg gttcaggtcc taaattgaaa
    43921 gaggtaaaac caaggtcgcg catatctttc aatgctcgtt tcaaattccc gcgaggatcg
    43981 ccggcaaatg gtgtcccatc cggattatag atatcacaaa ttaaacgagc aacttttcca
    44041 tgagcacttt cccacgggaa gatcatccaa gtggagagat ctggatacaa atacatatcg
    44101 ctttcttcaa ttcgaacaaa tccttcaatc gaagaaccgt caaacatcat tttattttct
    44161 aatactttgt cgatctggct cactggaact tctacatttt tgatcgtacc taagatgtct
    44221 gtgaacatca atcgtaaaaa tcgtacgttt tcttcctcaa tgattcgttt gatttcttca
    44281 cctgttatct gtttctttac catggtatcc ctcttccttt tttaatttat tcagtcaaag
    44341 aattgtcttt gcaatccttg cgactgataa tgacctgttt tgcttaaccc accttgcgcc
    44401 aaaatctcat cacgaaaaat ttgtcgaacg tcatgatctg tcaacggctt cttgtttttt
    44461 gcttcttgtt ttttcgcctg tgccatttcg tatacacgtt tgatcccagc catattcaat
    44521 ccctctgaaa gatagtcttt aatctcaagc aacatatcaa tatcattcag cgaatacata
    44581 cgtcggtttc cttcgcttcg ttccggatga actaaatctt gttcttcata atagcgaatt
    44641 tgccgagcag acaaatcagt cagcttcata actgtaccaa ttggaaatac ggacatagat
    44701 cggcgcaatt ccttttctcc catcagacgt cccctttcgt tttataagtt ggctaaagtg
    44761 taccaattaa aaaaaatatt gtcaactgca tatgttaggt tttctaacat gagatctcta
    44821 ttttttataa aataacaaaa aaataagaac acaaaaaagg tatctagttg attttcgtac
    44881 cagatacctt ttatttttta ttatactgta ctatccttta ttagtgtttt tatt
//
LOCUS       DADQDV010000019        40830 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.019, whole genome shotgun sequence.
ACCESSION   DADQDV010000019 DADQDV010000000
VERSION     DADQDV010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 40830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40830
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.019"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(326..1603)
                     /locus_tag="J8S10_001076"
     CDS             complement(326..1603)
                     /locus_tag="J8S10_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629674.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(1682..2326)
                     /gene="pcp"
                     /locus_tag="J8S10_001077"
     CDS             complement(1682..2326)
                     /gene="pcp"
                     /locus_tag="J8S10_001077"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HAZ9629675.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(2525..3469)
                     /locus_tag="J8S10_001078"
     CDS             complement(2525..3469)
                     /locus_tag="J8S10_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HAZ9629676.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(3471..4157)
                     /locus_tag="J8S10_001079"
     CDS             complement(3471..4157)
                     /locus_tag="J8S10_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HAZ9629677.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            4631..4951
                     /locus_tag="J8S10_001080"
     CDS             4631..4951
                     /locus_tag="J8S10_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HAZ9629678.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            5105..6010
                     /locus_tag="J8S10_001081"
     CDS             5105..6010
                     /locus_tag="J8S10_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAZ9629679.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            6007..6780
                     /locus_tag="J8S10_001082"
     CDS             6007..6780
                     /locus_tag="J8S10_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAZ9629680.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(6961..8385)
                     /locus_tag="J8S10_001083"
     CDS             complement(6961..8385)
                     /locus_tag="J8S10_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAZ9629681.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            8596..9042
                     /gene="nrdI"
                     /locus_tag="J8S10_001084"
     CDS             8596..9042
                     /gene="nrdI"
                     /locus_tag="J8S10_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HAZ9629682.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(9107..11089)
                     /locus_tag="J8S10_001085"
     CDS             complement(9107..11089)
                     /locus_tag="J8S10_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAZ9629683.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(11103..11999)
                     /gene="murQ"
                     /locus_tag="J8S10_001086"
     CDS             complement(11103..11999)
                     /gene="murQ"
                     /locus_tag="J8S10_001086"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HAZ9629684.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(12002..13063)
                     /locus_tag="J8S10_001087"
     CDS             complement(12002..13063)
                     /locus_tag="J8S10_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HAZ9629685.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(13274..13801)
                     /locus_tag="J8S10_001088"
     CDS             complement(13274..13801)
                     /locus_tag="J8S10_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAZ9629686.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            complement(13868..15370)
                     /locus_tag="J8S10_001089"
     CDS             complement(13868..15370)
                     /locus_tag="J8S10_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HAZ9629687.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(15628..16749)
                     /locus_tag="J8S10_001090"
     CDS             complement(15628..16749)
                     /locus_tag="J8S10_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAZ9629688.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            16875..17816
                     /locus_tag="J8S10_001091"
     CDS             16875..17816
                     /locus_tag="J8S10_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HAZ9629689.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(17966..18862)
                     /locus_tag="J8S10_001092"
     CDS             complement(17966..18862)
                     /locus_tag="J8S10_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HAZ9629690.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            19131..20471
                     /locus_tag="J8S10_001093"
     CDS             19131..20471
                     /locus_tag="J8S10_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAZ9629691.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            20689..21132
                     /locus_tag="J8S10_001094"
     CDS             20689..21132
                     /locus_tag="J8S10_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HAZ9629692.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(21636..23054)
                     /gene="nhaC"
                     /locus_tag="J8S10_001095"
     CDS             complement(21636..23054)
                     /gene="nhaC"
                     /locus_tag="J8S10_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HAZ9629693.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(23457..24680)
                     /locus_tag="J8S10_001096"
     CDS             complement(23457..24680)
                     /locus_tag="J8S10_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HAZ9629694.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(24711..25550)
                     /locus_tag="J8S10_001097"
     CDS             complement(24711..25550)
                     /locus_tag="J8S10_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HAZ9629695.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(25567..26247)
                     /locus_tag="J8S10_001098"
     CDS             complement(25567..26247)
                     /locus_tag="J8S10_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9629696.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(26249..27322)
                     /locus_tag="J8S10_001099"
     CDS             complement(26249..27322)
                     /locus_tag="J8S10_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAZ9629697.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     gene            complement(27969..28640)
                     /locus_tag="J8S10_001100"
     CDS             complement(27969..28640)
                     /locus_tag="J8S10_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAZ9629698.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(28727..31405)
                     /gene="mgtA"
                     /locus_tag="J8S10_001101"
     CDS             complement(28727..31405)
                     /gene="mgtA"
                     /locus_tag="J8S10_001101"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HAZ9629699.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASANGLT
                     EEQIERSRENYGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELVTGEKISEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGEFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLM
                     PLPGNYWLWLFATVIAYLALVTAVKKIYIRRFQELL"
     gene            32064..32501
                     /gene="ndk"
                     /locus_tag="J8S10_001102"
     CDS             32064..32501
                     /gene="ndk"
                     /locus_tag="J8S10_001102"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HAZ9629700.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(32523..33389)
                     /locus_tag="J8S10_001103"
     CDS             complement(32523..33389)
                     /locus_tag="J8S10_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAZ9629701.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(33549..35642)
                     /locus_tag="J8S10_001104"
     CDS             complement(33549..35642)
                     /locus_tag="J8S10_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAZ9629702.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
     gene            complement(36391..37014)
                     /locus_tag="J8S10_001105"
     CDS             complement(36391..37014)
                     /locus_tag="J8S10_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629703.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            complement(37173..38570)
                     /locus_tag="J8S10_001106"
     CDS             complement(37173..38570)
                     /locus_tag="J8S10_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAZ9629704.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            complement(38602..39573)
                     /locus_tag="J8S10_001107"
     CDS             complement(38602..39573)
                     /locus_tag="J8S10_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAZ9629705.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            39947..40372
                     /locus_tag="J8S10_001108"
     CDS             39947..40372
                     /locus_tag="J8S10_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629706.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
BASE COUNT        11807 a         8544 c         7136 g        13343 t
ORIGIN      
        1 gtgtcgtctt tgtataggac actgtagctg tgtcccattg aaacatctaa tgcaagaatg
       61 taaggcattt gttttcctcc tttttaagtt ttgaaagaac tttactgctt catttcgatt
      121 ccaatttcct atacacgggc tcatggcccc aacatacgta aacctgattc taaaatgaca
      181 gtaaagaagt tcggtttttg atagggactc gtagtcctca aggctttgtt cgaactttct
      241 ttcactcttc actataatct aaaaatagaa aatagaggag aacatcattc gtcaatgatg
      301 ttcccctcta atcttagtat gttttttata gtaattcctt cagatacttt cttgcctcat
      361 cattgaaacg cagtgattct tctaacttct gataatattc caacgcttgt ttctgagctt
      421 cagtaaaacg ataatgtttt cctttccatt tgtcgattgt ctcttgcaca tttccagatt
      481 ggatatcttt cactactagt tgccattttt cttttgagac tgtacggtct ttcttatcag
      541 cagattgtat agcttctcgt tctttacgca atacttttaa aaaaccattt ctgactatcc
      601 gaggaatgct gtcgaagaac ccttctgtaa aaccatagcg acaatattgc ttccaaataa
      661 atagatagat ttttggttgg atgaatcgtt ggtttttcgc aaaatattcc atctgagcag
      721 tgacttctgg tgttcgttga cgttttgtct ttctcaacac ggaaataaat gtttcaaaat
      781 aagcattagg atgtactggc acttcttcat atacgatgga ttgccaatct ttacgtaaaa
      841 atgcgcgata gttgatcaag aattcttcta catcctttac taattcttct gcaaagtcgt
      901 caaatagttc tttttttatc tgtcgctttt ttgactgccc attgatgtgt tcacttattt
      961 tcttgatttc attttccaat gcttgataat ccgctatgta aatcggcatt tctacttggc
     1021 gaaattctgc gagccgctga gctaatttta tatccggtaa atatggctgt ttcatccgac
     1081 gattttggta caagacaaaa cagtattttt gccatagtcc ttcaggaaaa tcgatattct
     1141 tctgcttaag ccataataat tcgtctaagg ccagatcaac ttttgtcatt ccctgatgga
     1201 tcgaagctgc cactgtcgga gagacatgca ggtgatcggc aaagtggttg atgcctagtt
     1261 ttaggatctt tccggttttt ggcgatttaa cgatgtattg cacttttaat tctctaccac
     1321 actcacaata caatttttgc tggcttcgtt ttgttcgaaa aaacggattg atcttgaagt
     1381 cagaaaacac ccaatctgtt gcagctaaat aatgttcttc cataaaacga gagctgatta
     1441 gatatcggcg gtgcttatcg actagttccc gctgtttttt cgttaatttt gcatagatct
     1501 cccaacgttg actgcttgtg tattgtttag aaattttgat gggatagctt ttgctgattt
     1561 cttttggaaa ccattcttca aagacggatt gccattcttc cacggctgtt tctttccttt
     1621 ctaattacaa aaagctggct actaacataa cgttagcaac cagccagtgt ttcttgctaa
     1681 attagtgagt tgttccggca tttccggaaa tatcttcttt attttctact gctgcttcaa
     1741 ctgcataagt caaagaagaa gcaatgtctt ctaaagacat agaaggcgta cccactggac
     1801 gatcgatcac ttgatcgggt gagaatggca cgtggatgaa cccacctcga attgccggga
     1861 attgtgtttc gatcaaatga agcaaacgat acatgatatc attgcagaca aatgttcctg
     1921 ctgtataaga gatgtacgct ggtagaccat gatcttgtac attttttgtc attgctttga
     1981 ttggcaatga ggtaaagtaa gcggctggac cgttttcttc taaagccgta tcgaatggct
     2041 gatttccttc attatcaggg attcttgctt ctgctagatt gattgcgaca cgttcgaacg
     2101 agactgctga ccgcccacct gcttgtccga cacagatcac gacatctggt tggtgctgtt
     2161 ggatggcttc tttgactact tgactgcttt tttcgaatac ggtcggtact tccactttga
     2221 tgatttcagc accgctgatt tcatctggca ttttttttac tgcttcatag gctggattca
     2281 ctttgtcccc accaaatgga tcaaaacctg ttactagtac tttcatctgt tgttcctccg
     2341 tccgattgat ttaacatatg gttatctttt atcataccat tttccttgaa cagcgtaaat
     2401 aaaggaaaca atagtttaaa taacataaca gatcaaactt aatatattct tataaaaaaa
     2461 tagtgttcca ctacaatgtt agaagaggtt gcgacaatta ttctgtcaca acccctctct
     2521 tctattattt aaatagaatc atataagcaa tttggaaaac tagcataaat aacgcaataa
     2581 acaactggtt tttgatcact ccgtatttgt ctttcatctc cagcatcgct acaggcacga
     2641 tattgaagtt agcagccatc ggtgtcagca gggtcccaca aaaaccgcaa gtcaatgcaa
     2701 ccattcctat taacgctgga ttcgctccat gactaaatac gaatggtgca ccgatcccaa
     2761 ccgtcatcac ggtgatggcc gcaaatgcat tccccatgat taccgtaaat atcaccatgc
     2821 caagagcgta aatgatgatg ccgatgttca catttccttc tggaacgatc gtacctactg
     2881 cattggaaat cactgtccca actccagcgc ttgtaaatac cgcacctaga gaagctaaaa
     2941 gcattggcaa catgcttaac ggccctactg tgcccagcat atctgctgca tcatctaaaa
     3001 atgtacttgg tcgattatct cgagaaaaga acatcaagat tagcatggct gcaaaaacac
     3061 cgacgcccac gccgactaaa gcacctaaat tggtaaatag agcaaacaag atcgcaaaga
     3121 caccgatact caaagctgga ataaaaattt tcattcctag tttgtctgac attttttcca
     3181 tatattcttt tgatggaagc cggctttctc ctttgctgac tttcttagca attgctggta
     3241 tggtcatcgc aaagatcaag ccaccgttca cgattgccgg aagccatctt cctcctgcaa
     3301 taactacccc taagaccgtc cagaaaaagg ctgacccata acgatgagga ttggttttat
     3361 ctgttaaatt tcttactcca gtgtaaatca atacgagtcc catcacgata taaaggatct
     3421 ccagtaattt atcgcctaat aaaatatcag gatttgtaaa aaagtccatc ttattgcccc
     3481 tttcctggat aatatttctt cgctaatttc ttttctttaa gatagaagta gacacttgcc
     3541 acaactaaag ccgtgatagc cactggaact tccactaaag caagctgtcc caatgttacg
     3601 tcatatccta gatctttcag tgttgattgg actagcaacg cccctgctcc tccgatgaat
     3661 agtacttggc caaagaacca gcagacattt tccatagctg aagccatacc ttttagttct
     3721 tcttcatgct taggatggac ttctaaccct tttgattcga tggtccccaa tgccatcggt
     3781 aaaatgattg gacgaacaaa tccagcaact ccaccaaaac tcacgttaaa agccgcaaag
     3841 atcattcgaa agatcccata aatatctaca atcataccag cagatacttt cttgaatcgc
     3901 ttgatcaagg aagccgctga ttctttcaga ccatttcttt caagcgttcc tgttgccaac
     3961 ataatgatga taaaaatcgc catcccgcga ttgtttacaa aacttgtacc taaaagttct
     4021 aacattcctt gaatgccaag accgccagtc aaagctgtaa caactaaagc aaccattacg
     4081 atcaatatcg agtctaattt aaatgcaaac ccgagaataa caatcaagac gcctaaaagg
     4141 ctaagataat tttccatata ttttcctcca taaaatgaca atattttttt aattataaag
     4201 caaaacacat aaaaaatata gttgttttct cacgaaatag acactatttt taaatatttt
     4261 tcgttatttt tttatcacaa aaattatctt acttattgta aggtaaagct ttttttaatt
     4321 tattgcccga taatatatag aaataaggtc tagttactgt tttttttaaa tgattaataa
     4381 ataacaactt ctttctatga aattgcaaag cattcatctt cttttccgct aacgatatat
     4441 ccgtcagtgc ttggtacact ttactaaaaa gtatgagatt gccgatatct ggataggtgt
     4501 gctatactac agaaaaagat atacaatctg ccaccgggta ggataaagag gatgatcatt
     4561 ccattaggtc tttgaaggga tgattttcct ctttttgtgt atttttttat agttaaggag
     4621 gaatgtaagt atggcatgga tggaattaat catagcagga attttggaag tattctggtc
     4681 aacgatgatg aaatggagtg atggtttttc taaaatcaat tattcttttt acacagtgat
     4741 tggcatgatt gctagttttt actttttgtc aaaggcaatc aaaagtttgc cgatgagtct
     4801 ctcttatcct atctggacag ggattggcgc agttggttcg gtcataattg gtgtggtctt
     4861 gtttcatgat aagctgaatc tttccacttg gttctttgtg gggatgctac tcatcagtat
     4921 cattggcatc aagattacta gcggccacta gacacttgga ataagtactg atcagaaaaa
     4981 ataagccttt ttatttaata ttcaattttt ttatgaaaaa ataagaaata agtccaatga
     5041 cctagcgact tctccactca tcaggtgtat gcttgtacta tctatagaaa aggagtgaat
     5101 atttttgaaa agtctttcgg tccaagaatt atccaagaac tttggtcaca aacaagccct
     5161 cagcgatgtc agttttagct tatcccctgg caaaatcgtt ggattagtag gtcctaatgg
     5221 cgctggaaaa acaacgatca tgaaagctat tttaggactg atccattact cagatggaac
     5281 aatctgtatt ggtgaaaatg agatttctcc ctctagtcat aaagggttgg aacaagtagg
     5341 agcattgatc gaatacccgg gtatctatcc attcttaaca ggctatgatc atctgaagtt
     5401 attctctgaa accaacgatg tatctgctat cgacactatc gtgaatcagc tcaagatgga
     5461 aaagtacatt cacaaaaaag cgaaatccta ctcgttggga atgaaacaaa aattgggaat
     5521 tgctcttgcc ttactgaacc atccgtctat cgttatttta gatgagccga tgaacggttt
     5581 ggatccacaa gcaacaagag atgtgcgaaa aatcattacc gacttggcta ctcagggcac
     5641 ctctttcttg atctccagtc acttactcag cgagcttgaa aaaatggtcg atgagctgat
     5701 cctgatcaat caaggaaaga tcatcaaaca atgtacaatg gctgaattga accaaacagc
     5761 gcaagatttc atcgttatct ctacaacaaa tgatctagct gctcgaacga tcttgacaga
     5821 agctggatat actttggaag atcctgataa aatcaagctt ttaaaagaaa acgaagaatt
     5881 attaggaacc gtgatccagc tattgtctgc acaaaatatc catgtgacag acgtccagca
     5941 tctgacgaat gatttggaat cttctctatt ggaaattctg gattcagtaa agggggaaga
     6001 agaaaaatga cattgcttgt aaaacaagaa ttatttaaat tgatcaagaa aaagtcaact
     6061 gctgttttat ctgttctatt agttgttttg ctcataggaa cagcacttct agccaaaaaa
     6121 tacacgacga tcattgatcc agttgaaatg actgctcagc tttttagtgc cacatcttgg
     6181 attgtcttta tcatgattgc agctgcaagc acgatcattt cgatggaagc acaatatggt
     6241 acattgaaaa atctccttta tcgaaagtat tctcgaggag aaatattagt aagcaaatgg
     6301 atcacattag ttatttattc tgtttattta taccttttag ctattattgt cactgtgttg
     6361 atgaaactga ttcttttccc ttcgatttcc ttcacggaga aggtttctac tggtcaaaca
     6421 ctgatccaaa gcttgttcac ttatactttg ggtagttata tcggtttatg gctgatttta
     6481 agtttagtgt tgatgattgc ttgctttatc aatagttccg gcgcatccat ctcagcagga
     6541 atcgtctttt attttgcttc gtcaatcata tctggtatcc ttattgcact catccaaaaa
     6601 tgggagtgga tcaaatggaa tccgatcagt atgttgaatc tgcaaaacca aattggaaac
     6661 gaagagatca tgaagcaatt gactcatctt tctactaatc aaatgctatt cggtaattta
     6721 gcttacatcg ttttgttctt agcattagga tatctcgtat ttaagcgaaa aaatgtatga
     6781 tgactcatca aaaaagaggc tgtgaaagag acgttcagcc ttattgccga ttggctgtct
     6841 cttaaacacc gtttattctg aaaaaggagc tgtgacaaca tttgtgtcac agctcctttc
     6901 ctagtatgtt tttgaataaa cgacaggctc acaacctctc tttatacttc ttttatactt
     6961 ctatacgtga agcatcccag tggcaaataa aaccattgca atcactccga ccatcgtcac
     7021 acctataagt aaaatcttat ctaagtggat atgttgtaca ggctcgtttt gctccttacg
     7081 tgctttgagg taaaaataaa tgcctggcaa gaaaagaaca agaacaagca ttacttcatt
     7141 aaaggctacg actagcatag cccatacttg aaaggcactt gctaaaagcc ctactaaaaa
     7201 ttggacccat tctttccgct gataagaaag tttcatttgg tacaatccta agaaaagcca
     7261 cgtgaagaaa atagctgctg taccaagtgt gtaagcaaag ttataagcac tgtcagtgaa
     7321 taataatgaa agtaaaaaga cattcgtaca taacgtcgtc aatacgatag cataagttgg
     7381 tgccccattt ttgttgagtt ttccccatgc tttaggcaaa agtccgtctt cagccatgtt
     7441 tcccattgtt tcaatcggta agatcgtcca tgagagccaa acaccaacta aagaaatgat
     7501 caaaccgccg ttgatcacga ctgctcccca tttaccaacc atcatttcaa acacatagcc
     7561 catagcaggc tgcgccttga tcgtttgcag ctgattcatc gtcattgtcc catatggaag
     7621 catggaaacc aagacgtaaa taataatcaa gccgaatatc cctagaatcg ttgctttccc
     7681 aacatctgat tgtttttttg ctcgtgaacc tacgacagag gctccttcaa taccaacaaa
     7741 tacccaaagc atcaccatga tgcaactcaa tacttgactg gaaaacggga tcggctgtcc
     7801 attcgcattc aatataatgt cgctagaaaa gttatcaatg aattgttgga tcgaaaacgt
     7861 gctgatagct actacaataa ataaaaataa tggcactaat ttacagaatg tgacgatagc
     7921 attgacgaaa ctagcatttt cgactccccg attcactagc catgcatatc cccataaaaa
     7981 gactgtactc atcacgatcg atgccagatt ttgcccacct tcaaatactg ggaagaaata
     8041 tcctaatgcg ctcatcaaca atgttgcaaa agctacgttg cctaaccagc atgtgagcca
     8101 gtaaccccaa ccgctgataa aaccagcgaa acggccaaaa ccttcttctg cgtaactaaa
     8161 gatcccgcct tttaaatctg gacgtttttt attgatatta ttgatcgaca aggagagcat
     8221 caacattgct gttcctacga gtacccaact gaaaatagct gggccgccag ccgatccgga
     8281 gatgtccgtc ataataccaa atacgccacc tccaatcgct gaaccaatta ctaaggcagc
     8341 aagtggaatt aaaccaattc cttttttctg ttgctctgta tccatgtaag catcctccaa
     8401 aataaaaccg cttttatcaa aaagtataac aaaccttttt tatttttact taattaataa
     8461 aaactttaat agaaatataa ttctaccggc ttttttctca ttatacaagc aaagcgccta
     8521 gtccctttcc aaattacacc accaaaaaac ttaaaaaaga tgctatacta aaaggaaaga
     8581 attggaggat gatccatgaa cattttatat atatcgattt caggaaatac gcgtgccttt
     8641 gccaaacatc tagcagaata tgctgaaaaa atgcatgcag aagatcctgt caatcctgaa
     8701 gttactttaa aagaaatcca tgaaaatagt gattttacga aagaaacaga accatttttt
     8761 actttcgttc ctacttattt agacggcgga aatggtttag ataacggtga tacagaaatc
     8821 ttgaccgaaa cgatgcgtga atatctggaa catgaagaca atcataaact ttgtcttggt
     8881 gtagtcggta gcggaaataa aaacttcaat aatcagtatt gtctaacagc caaacaatat
     8941 gcacaaacat ttggctttcc tttcttggca gattatgaat tacggggaac accatctgat
     9001 gtgacacgaa tttatcagat tttagcagaa aacaataaat aataaaaaag aagaagctga
     9061 aaaatagatt tcagtttctt ctttcgtttc tattgtttct atcatattaa gctttgacat
     9121 ccatcacagg tgcttttgct tttgctttac ctgttttttc caagacaaag ttttttacac
     9181 gatccatatt ggttaccaag acgatcatgg atgtttcttt gcctgctgct ttgatcgctt
     9241 ctaagtcagc ttctgctaca agcgtatcag gtgtcacttg ctgcccttct gttactttca
     9301 catcaaatgg cgtaccgcct aagtcaactg tgttgattcc catatgaagc aagatttcta
     9361 aaccatttgg cgttgtgatc ccaatagcgt gtttcgttgg gaagacagag ctgactaccc
     9421 cagtaactgg agaatagata tgtccgtttt ctggttctac aaagtagcct tcacccatca
     9481 tcttttgtgc aaaaactgga tcacttgctt tatctaaaga aacaactgtt ccgtcagcaa
     9541 ctgatgagag gatagtcaca ctttcagctg aagtttgagg tactactttt tcaggcactt
     9601 catttactgt ggctgtttca gtcgctaatt cttctttttc taaacggtct ttaggaatac
     9661 cgaagaagaa tgtagcaacg aagccaccag cataagctgc caataatcca aggatgtagc
     9721 ctaaccattt accgtcagag atcaatggga tcaaagcggc tcctgaaggt ccaatagcga
     9781 tagccccgac atttccgatc attccgatca ctgccccgcc gatacctcca ccgatacaag
     9841 cagtaataaa tgggcgtcct agaggtaatg ttactccgta aatcaatggt tcgccgattc
     9901 ctaggatccc gactggtaaa gctcctttga tcatttctgt taattcttta tcttttttgc
     9961 agcgaatcca taatgccaat gctgcaccca cttgtcctgc accagccatc gcaagaattg
    10021 gaagcaatag cgtacgacca gtttcatcaa tcatttgcac atggattgga gtcaaaattt
    10081 gatgcagtcc gaacataacc atcggcaaga ataatgtgcc tagaacgaag ccggcaaatg
    10141 ctccaccaac gccaagtacc cagttgatcc caccgaccat gccatcagaa atgaaacctg
    10201 ctaaaggcat gatgaagaaa atttcaatca gaccgatggc aatcaatgaa agagttggtg
    10261 taacgatgat atctaccgca tcaggtacta ctttatgcag ttttttctca acgattgaca
    10321 atagccaaac agcgaagatg acacctagga tcccaccttg tccagctgca agagcttcac
    10381 cagtaaataa gtttttcagt ggtgcttccg gattcatccc tgtcagcatc acaacggccc
    10441 cgataactcc accaagagtt ggtgttgcac caaaaacttg tgcagcattg atacctgtat
    10501 agataactag gtagctaaac atcccgtttt tcaagatgtt catcacatcg atatattgtt
    10561 gccatgttgc tgcatcaagt gttccggctg tgactaagtt tgctaaaact gcggcaatcc
    10621 ctgccacgat cccagtaccg acaaatgcag gaatcattgg cacaaagata ttagaaatgt
    10681 cttttaatac cgatttgatt ttagatggtt tttgtttcga tttttgtgcc gctttcattt
    10741 cttgtgcccg ttcgtttaca cggtcttttc cagatgctga tgaatttgct gtagctgtac
    10801 ttacagaaga aagtttttct cctaatttca cgcctgccaa atcaaccatt tgctgtgcta
    10861 ctttgttcac tttcccaggt ccgatgatga cttgaagctg ttcatcttct actacaccaa
    10921 gcactcctgg aatcgctttt aattcagaga catttacaag atcatcattg atgatcttca
    10981 tacgcacacg agtcatgcag tggacaatgc tttctacatt gcccatgccg cctgcccctt
    11041 tataaatttg ttttgccagt tcttccaaag tcagttcgtt ttttgccatg gtcttttccc
    11101 cctcataagg tcccttttac aaatccgttt gcttcagcta attttgcttg agcttcctct
    11161 ttatcactat ttgtcaaaat catgacgata gccagcttaa cattttgatc tgcttcttca
    11221 aagtactttt cagctgtttc gtaatcagct tctgtcgctt gcatgatgat tcgttttgag
    11281 cgttcgatta gtttttcatt tgttggtttg acatcgacca tcaagttatt gaatacttta
    11341 cctataccaa tcatactgat agtagaaatc atattcaaga taagtttttg tgctgttcct
    11401 gacttcaatc gagtagagcc tgtcaaaaat tctggacctg catcgacttc gattgggaaa
    11461 tccgcgtgtt tactgatttc ggcttgttta ttgcaagaaa tcgttcctgt gacagcaccg
    11521 atcgattttg cgtaatctaa tccaccgatc acatatggtg tacgaccgct agctgcgata
    11581 ccaataacta tatcattttt tgtcaaattc agcttgatta gatcttcttg ccctagctca
    11641 taagaatctt cggccccttc gacagctaca gtcattgctt cttctccacc agcaattaga
    11701 cctatgacca tttccggttc tacaccgaat gtcggtacgc attcagcagc atctaacaca
    11761 cctagtcttc cacttgttcc ggctcccata taaatcagac gtccaccttt tttaaaggac
    11821 tcaatcgtgt tagcaatcac tggttcgata cttgtcagtt ctttttcaac cgcagcggcc
    11881 actttctgat cttctttgtt cattagttga acggcttgag aaatactcat ctcatctaat
    11941 ccaaaagttt cttggtttct gcgttccgtt gttaggttct ctaaattgat tttgctcatt
    12001 tttatcttcc ttcttttctt ataaattgat agttcatacc agctttgatt tggttgatca
    12061 atggtagctc ttctttgata actttagcta ctacattcac tttttcatcc gctggcaaat
    12121 catatttggt taattggatc tcacccatat agcgcaaata cttttcgtta tctaaagtaa
    12181 tagacccttt catacgcgta gctgtatttc ttgctgggat aggcggaatc tctcgaaaac
    12241 gtgcatctac gcttcgtatg acatctcttg catcgtcttg ccgattcgta tgcttcccta
    12301 atatatattc gtaaaattct tcatctacag gttccgtatg gagcaagact gtctgttctt
    12361 tttggaaaga agcaaattgc tcctgaacgt tttctgacag acctgcatct ccgatgtaaa
    12421 caatatccgt gttacttgct aatagatcta gagcgcctgc aagaggatgg atccctcgat
    12481 gttcttccaa agttggcaat ccttgatata gtgggcctct caactctgta tctcctggta
    12541 caaaaccttg gacaaggaga ccttgaattt tgagccattg attttttttc tgataccatt
    12601 ctttgtccag ccctgtttcg ggacgtggat aataattatg ccaagcttca atctgtgaga
    12661 aatcagcttc tgcttctttc aattcatcga tatctttagg cgtgatcgtg ctagcattca
    12721 aactgatttt caattgatgt gaccagtcgg caatctgctg attggaaata tgataatcca
    12781 ttcttaaacc tgttacacca attgctttca aaggcgttag atcttctaat gaaaaacccg
    12841 ctcgttccaa tgcctctcct gaaatatcga ccatcaattc tagtttattc tttttcgctt
    12901 cgcttcctag ttcgatcaat cgcttttgat atgccgaaac atcatcttct ggtatatgca
    12961 tggaagtgaa aataccgaca aagccattgg atgccatttg gcggatatac tgtttcttct
    13021 cttctgacaa agaatcgttc ataaatattg aaaagccaaa catattatcc ctctttttct
    13081 gtatccgtct tcatttctat gactagagta tatatctaaa gaaacaaaat ttcaatactt
    13141 ttattaaaat aattaaattt catttctaaa ggttgagttt atattatcaa aagaattgtc
    13201 ataacctaaa aaaggcactg ctaagcaaaa gcagtgcctt gaaatatttt atttaaataa
    13261 cacaaaaaca taattactca taagaaacca attctgtatt atctaccatg aatgtaaaga
    13321 acccctcatt aggcatcgga tgaaaataag cattgatcac tcttatcaag gcattatggc
    13381 aaactaacag atagacattt tcttcgtctt cgatgcattc tttcaataaa ggaacgatcc
    13441 gtgcatacac atctaagact gactccccat ttgggaatcg tacagcgaac gctaaacgtg
    13501 ctttttgaaa gttctcatct ttgcttggca gtccatcata atccccaaaa tccatttcta
    13561 ccaatcgttc atcaacggtc agcggcaagc tgagacgatc agcaactgct tgtgctgtat
    13621 ctcttgctcg ttgaagaggg gaatggatga ttttcgtgat tggaacaggc aaatctacta
    13681 ccttttctgc tagtttctgt gcctgcatct gtcctttttc agtcagcggc acatctgccc
    13741 gtccgcaaac taatccttgt gcgttccaag ttgtttctcc gtgtctcgtt acataaagca
    13801 tgtgattctc tccttcgttg gcaaagttcc ccttaaccat accttgttgt tcttgagatt
    13861 acaagggtta gattctctca agagaaataa tctcagtaga tactttatcc aggaaggttt
    13921 gatcatgttc cactagtaac atggcaggtt tcacgttcaa gatcagttgt tctaattgtt
    13981 cttgattgaa gacatccaaa taattcaatg gttcatccca tgtatatagt tcagctggct
    14041 gtgataaaga tttagccaat tccacttttt tccgttggcc catactcatc tgctcgatct
    14101 tgttatgaaa aacatctctt tccatcccaa gctttcggag gttgttcaaa aatgcttggt
    14161 agtctacttg gtttttctct gcaaattccg ccaacgttcc tcgattgtct tcataatttt
    14221 ggcttgcata actaatgctc agatgttttg gctggtattt ttctcctata accttgccgt
    14281 tgaatgcccc cagaagataa tggataatgg atgactttcc tgcaccgtta ggacctgaaa
    14341 tcgccacccg ctgatgaggc tcgattgtaa aatgaattgg ctcgaataac agattttcat
    14401 accctaattg aagatcttct acgcttaaaa gtcgcttatg gtgagacgct tggctattca
    14461 tcgtcaaaga atcgatatat tcgatatctt ttaatagttt ttctttctcg ctgatctggg
    14521 tctccatccg attcacgatt gctttggatc gtttcatcgt ccgtgcagca tcagcaccca
    14581 ctgctccttt attcactcgt ctagattcag tatcgatgaa tccgacttgt ttctttgttt
    14641 tatctccttc tcgggaacga gaccattcgg ctttttcagc tgctgttttc tttagcctac
    14701 tgacttcttt tttcaatttt tcattttgag ccatttcaaa ttcatcacga agttttttct
    14761 gttcttcata gatagagaaa ttcccttgat aaagttccag ttgacttttt tcgattgcta
    14821 aaacatggtc cactacttca tcgataaatc cccggtcatg gctgaccacg atgaagcctt
    14881 gttttttctt tttcaaataa gccgctactt gttttctacc agagatatcc aaatgattcg
    14941 ttggttcatc gattaacggg aaatgagtgt catccacaaa taaaagtgcc agtaggactt
    15001 ttgtcttctc tccccccgat agtgtgctga attctctcca taagatttca ggatctgttt
    15061 gcatcaattg gagctctctt tcgatttccc atatctcaaa atccgtaata tcatttaaca
    15121 cgtaataggt taaacgttct ttatcttttg tctgttgcgg gaaataggca aattcttgct
    15181 gatggattac ttgcccttga taaggtagtt tgttttgtag aatattcagt aaagttgtct
    15241 ttcctcgacc gtttcgtccg ataagtccta gtttccattg tgtgtcaaaa tttagatttg
    15301 cttgttcaaa taataatgtg ccttggctgt cgtagccgaa tgtcagattt tttatttcga
    15361 ttttagacat tttccatcac ctcgtaaaaa aagaccagtc ctattttcag aactggctaa
    15421 agaggatgca agggttggat acacacaaaa agacccatac atcgaaaaaa ccaagccaat
    15481 cccgaaaatc tgcacactgc ttccttgtct ccacaaggta cagtctgaat gcagctttca
    15541 tcaatcgact taatttttca atgcacggat ccctcacttt gtcctatatt tgaaattacg
    15601 atagcataaa gaaaatgatt ttgtcaacta cttcgggagg atggtgaaaa atctgctaag
    15661 tgtctgtcct aagatttttg ttttttctaa tgtttgcctg tgttccattg cttcttctaa
    15721 acctattgga cccaaatgaa tacttaagac aattgggaga aaatcagaaa gtccttctag
    15781 ctcttggtct ctacttccgc aaatagcgat tattggtttt cgatattttt ttgcaagcac
    15841 tgctacaccg tatggaactt ttccgtggat cgtttgctga tcgatccgcc cttctcctgt
    15901 aatgatgaca tctgcttgtt cgatcttttt ttccaatcca gtgatttggc tgactaaatc
    15961 gaaaccagaa accatcttcg ctcccaacaa aaaaagggct ccaccaatac cgcctgctgc
    16021 tccacttcct ggaatatcat ctaaatccac ctcccagaaa tcttttattt gctgagcaat
    16081 ctttcctgct tgtttatcta agaaagctag cgtcgtatct attcctcctt tttgtcttcc
    16141 aaattgccaa gcagctcctt gttgacctgt atatggattg gtaacatctg cagcgataat
    16201 caattttact ttagaaacaa gaacgtttct tcgatcaaaa tgaagttttt tagtagataa
    16261 taaaggattt ccttctgtgt acccttctaa agaagcaccc aaggattgga gtaatcctag
    16321 accaccatcg ctacacccgc ttcctcctaa agtgacaata atttgttcta cttcttgaag
    16381 cagtgcatct ttaataagtt ctcctaaggc ataactggaa gcaagtcgga tagtttgatc
    16441 cgttggttta tcaagtagat ctaaccccaa tgcttgtgca gattcgatga ctgcggtgtt
    16501 ttttccttgc caagttgtca ataaatagct gatttttcgc tgacggaata agagatccat
    16561 cccatcaatg gtacgccatg ttcccctgag cgcgtaatag attgcttctg cagtattttc
    16621 tccgccatct gcaatcggca cattgatttt tcttccttta cgatcttccc agccatttag
    16681 aactgcctga tttagttcaa atgaagaagc acttccttta aatgaatcaa ttgccgccaa
    16741 aatatccatc tgtatccctc actttcttct taagtaagac actttttttc atttttttca
    16801 aacaaaacaa tgctattttc ttccattttt ctatatacta aaagggaact cattgaataa
    16861 aggagagaaa aaacatgaaa atcgcaatag ctggggccgg agcaatgggc agccgaatcg
    16921 gattgatgct acatcaaagc ggaaatgagg tcctcttgat cgatcgttgg cctgctcaca
    16981 ttgaagccat tcgtacaaat gggttgattg ctgactttaa cggtaaagaa gtggtcgcaa
    17041 aactgccaat ctattcacca gaagaaatca tcgaaagcaa cgaacacgtg gacttgatcg
    17101 tagcattaac aaaagccaat caattagatg atatgttttg ttcgatccaa tccattatta
    17161 ctgacaatac ttatgttttg tgtttactaa atggattagg tcatgaagat gtactggaaa
    17221 aatatgtgcc aaagaaaaat atcttatttg ggatcacgat gtggacagct ggtctagctg
    17281 gtcccggaaa agtcacattg ttaggtgatg gagaaatcga actagagaac ttggaaccag
    17341 aaggcgaagc atttacaaaa aaagttgtag aagtctttca agaagcaaat ttaaatccga
    17401 tctatagcca taacgttcgt tattccattt ggcgaaaagc ttgtgtaaat ggaacattga
    17461 atggtttatg cacgattttg gattgtaata ttgctgaact aggcgcgcaa aaagcggcag
    17521 agagcatggt tcgaacaatc gtatctgaat ttgcttctat cgcagcaaaa gaaggaatca
    17581 tactagatca agaagaagtg taccaacata ttgcttctac ttatgatcct gacaacatcg
    17641 ggttgcatta cccatctatg taccaagacc tgatcaaaaa ccatcgtttg actgaaatcg
    17701 actacatcaa tggtgccatt tggcgaaaag gacaaaaata tgatattgct acaccatatt
    17761 gtgccttttt gacccaatta gtccatgcaa aagaaggaat ccttggcgca gaataaaagg
    17821 ctctctgatg agaatcagct gaatcagcag ctggttctct ttttttaagc ccaataaaag
    17881 atcaaaaaga aaacacaact ctcatgatgc cataagaatt gtgcttgttt gtttcagtac
    17941 ataatctctt caaaatgtag gttttttatt tgttttcaac agaggagagg tcatattcgt
    18001 attgctcata aatagtggaa tcgttagtga taaatcgttt tgcccaattt tctgcatcat
    18061 aaaattccaa tagctctgat aggattggct taaatggtgt atgcagaaat tccggtaatt
    18121 catctaaatc acgttctcga agcaaaaaaa tattttcagg acgataaaaa tgataatgag
    18181 caatcgcttg attatccgtc actagtttct tttgaaaata catggattca aatgtccgca
    18241 aagtcactcc ttgctgaccc tcccgcaaca gttccagaat cccgcgcgat tcccctgttt
    18301 ttttcaggta ctcttcataa gtaagatatc caggttgttc attccctcga tgtggaagaa
    18361 tgaaatagtt ggtcgtaaca tctcttttta taaattcctg cttatagctt tctgctcgtt
    18421 cttttctccc attattcgtt gcaccaaaaa atagatccgt ctttggttcg ctagaagaaa
    18481 aattcatatg tttcgaataa aatgaactat tatgtttcag cccaagttct tttgcttcca
    18541 aaaaatcaaa atgataaatc tcatcgattg ccggttcatc ttgtgcctgc ttcagcatcg
    18601 cctcgtgttc tgctttgaag tgattccaaa aaaataacac aatttttgca ttggtaaatg
    18661 ggcgcacgcg tcgagccatc tccatatcaa atccataatc taaaaaaacg atcagctgat
    18721 aatttgccaa ctgttgtcta gctgatttaa tgaattccga ctgtagtaaa tcttttccgg
    18781 accaaacatc taaagagcgg atggaaggca aaaaataaag tgatttattt tttgcaacta
    18841 gcagtacgtc atttttgttc atcttttccg cctcactttc tctgtcactt tttcctatga
    18901 tagcctgttt aaatagtaaa aagccagtaa aacgtttcct atatttgtat gaaaatttaa
    18961 catttgtatg aaaatatgat gaaataaatc attcttctat taaaattcgc ctaaaagttt
    19021 tctgaatagt tgtaattgtc tgaaaatttg ttatcattag tcattgttaa atattgctat
    19081 ttattcttaa tataaatttt gattgtgaat ttaaaagaaa gaggtcattt atggaagata
    19141 aaaaattgaa aaaacaactt agctccagac atatcaccat gttagcttta ggtggagcaa
    19201 tcggtgcagg tctatttaaa ggaagtggcg aagcgattgg gatcgccggc ccttctgtat
    19261 tgattgcttt tttgattggt gggctgattt tatatatcgt gatgaaaggt ctgggaaaaa
    19321 tcgttttaag cggtggcgac acgcatcacg gattatctgg tttgatacgc ccttatctag
    19381 gtgctcattc tgctgatttt actgattggg tctactggtc tatgtggatt atcaatatca
    19441 tcgctgaagc tgttgcagct gcttcctttt tgcagttgtg gttcccgcac attccagcct
    19501 gggtatttgt ttttatgttg gctgttttaa ctacgatcat caatctttat tcggtacggt
    19561 tattcgcaga aacagaatat tggctggctt ttgctaaaat cagtgtcatt atcttactga
    19621 tcatttttgc tacttatctt gtcggtcagc aaatgttggg cacaggcgtt ttccctaccc
    19681 ttcagcaatt gactgaccat ggtgggttta ctcctcatgg tatgaaggga atcatcagtt
    19741 ctttgcttgt agttatctat tcttacggcg gttctgaact gattgctatc acggtaagcg
    19801 aagcagatga tcctaaacgt gcgattccta aagcaatcaa aggtgtcatg ggaagaatca
    19861 tttcctttta catcattcct ttgtttttgc ttttgattct ttttccttgg aatactttag
    19921 caggcacgaa tgtcagtcct tttgtgatgg tatttgaaaa aatgaatatc ccatttgcag
    19981 cggatatcgt caattttgtg attgtccttg ctttgttctc atctatcaat tcgggtgtgt
    20041 atgcatcttc aagaattttg ttcttccgtt tgaaggatcg aaaaggttcc tctagaaaac
    20101 tagctgtttt aaacaagcat caagtaccgc aacgtgctgt tttattttgt accagtgttc
    20161 tttatcttgg tgtagctctt tcttattttg tcggtgacaa attatttggc tatctggcag
    20221 gttccctttc gtatacagta ttattgatct ggatcattat cagtgcggca tcctttgtac
    20281 tggcactaag aaaaggaaca ttatgggata aaggaatcag cttttttgca ttagctgtct
    20341 taggattgat tttccttggt atcctgttca cgaactccat tggggtaact gtattgactg
    20401 gcctgcttta cctgttcatt tatttcagtt atcaaaaaaa gaatgatgcg ttcgtattga
    20461 cgaatgaatg aaatcgatag aaaattttat tttatttatg tggaatagat ggagctattg
    20521 aagaaaggag ttgtgacaaa agtcttgttg caactccttt ttccgaataa acagtctcat
    20581 gacctcttgg taaacggtgt tcaaaaaccc tctgtgcaaa ataattgatt gttctccatg
    20641 ctcatgacat gatagaagaa aggaatgaaa aaaaggagtt tgttttaaat gaaaaagtat
    20701 tggaagtttt tgttgatgat cggtgtttca acggtagtta tgtttggtat gatgtacttg
    20761 aatgtctatg cgctcgatca tatcttcttc agtcgtacac gagtattcat ggcgttgatg
    20821 atgggtgcag tcatggcagt catcatgctg ttgttcatgt ggaaaatgta tgaaaacaaa
    20881 aagataaatg ttatgatctt agccgctagt cttcttgttt ttgccggttc cttgtttatg
    20941 gtacgaagcc aaactactgt caacgacaca gcttggatga aggccatgat tcctcatcat
    21001 tctatcgcta tcctggcaag taaacgagct gatttaaaag atcctgaagt aaaaaaatta
    21061 gcggaagaaa tcattcaggc acaagaagaa gagatcgaca aaatgaaaaa aatgatcaaa
    21121 gaaatggaat gaccattatc cgtccaaata aaaaaagagg atgttccaga agttatcagc
    21181 ttcaagaaat aagaagaagc tacttctgga acgccgtgaa taaggggttg tgaaaaagct
    21241 gccctgcatc aagtaataag aacagccaaa caaaaatagc ttctcctatt tttcgtttgg
    21301 ttaggcttat taccgcagat gcaagctttt gaacaccgtt tattaagagg ttgtaaaatc
    21361 agcgttctga cctgagtatt agagagacaa atggaaaaat agttcctcat attttgccat
    21421 tttttgagct aataccgagg gtcagctgat tgaacaccgt ttatcgagag gttgtgaaaa
    21481 agtcgcttag tttcgcgtat taagaaaaat tttgtgaaat ggctttccac atttttgtat
    21541 aaatttggct taataccgag aaactggctt ttgaataccg tttattcgta aaagggattg
    21601 tgacaaaagt cttgtcacaa tcccttttta tgtttttatt gttctaattg cgctgtcttg
    21661 cttactgctt cttgcggttt cacaaatttt tttgagattc cccaacctgt gaaggcactg
    21721 accatcgaaa acacaggaga aagcaaactg aaaaatacga atggcaagta agtgagtgta
    21781 ggaataccaa atgtacttgc tacgaaactt ccggcaattc cccaaggcac taagtagttg
    21841 attactgttc caccatcttc tagcgttcta cctaatacag ttggatcaaa tcctgctttt
    21901 tcataagttt ctttaaatgc attaccaggc agaataacag ataggaattg ttcaccaata
    21961 aaaatattta ctccgatact tgtcatcaat gttgtaaaaa tcaaatttgg tgtgttcgtc
    22021 atctttcttg atactcgttc catcacggtt gagatcaagc caaattcgat caacaatcca
    22081 cctaatgaca aagttagaat aatcaatgac acagtaggca tcatactttc gattcctccg
    22141 cggctaagca gtgaatcgat ttgttggttt ccagtatttg aaacaaaccc tgattcgatg
    22201 accccagcca acttcgttaa ggaagtttgt gggttttgaa taaaaatcat tcctactgct
    22261 acagcgatat tcaacaaaat cgttaaaatt gccggcacct ttttccatgc acacagtaac
    22321 attaaaaata aaggaatcag tgaccagatt gaaatagtaa agtttgcttc tagaacatca
    22381 gtcacttcac gaatagatga aagacttgcg gctttacttg tgtgtcctaa aatcatgaat
    22441 aaaaagaaag aaacaacaaa tgccgggaca gttgaccaca tcatatgctt gatgtgtttg
    22501 aacaaatcgg catcaacaat agctgctgct agatttgttg attcggataa tggagacatc
    22561 ttatctccaa aaacggcacc tgaaacaata gctccaacaa ccagcgctgg atttaagcct
    22621 agtgttgtcc caataccgaa aaatgcaatc ccaatcgttg acataacagt aaaggcactc
    22681 cctacagcgc tacctacgat tgcacacaca acaaatacag aagggacaaa ccactggaca
    22741 ctgatcaatt tgaacccaat gaccattaga gttggaatga tccctgcttg tatccataca
    22801 gcaatcaatg aaccgactaa aataaaaata aagattggga tgattcctgg tttgatgcca
    22861 ttgatgattc cttcgtgcag ccaatctgtc gggtatcttt ttatcactgc atacaacatg
    22921 accattccga tcgctgctaa gatcgtgata ttaggtgaga cctttaatcc gacaacgcca
    22981 atcgcaatgc ctaaaacaat aaccattaat acaagtgttg cttctaaaaa acttggtgtt
    23041 cctttttttc ccatgataat ctctcctttt ttagttgttc ttatgttcta aaaaagttaa
    23101 gatatcggat tactccgccg caattcatcc gcgattcctc ctttataaaa ataaaaagac
    23161 ctgttttaaa ctaaggacga atgactccgc ggtaccacct taattaaaaa cagatctgtt
    23221 tttcactttc aaacttttat tcaaatgtat ggactttcca tgtaattcgt caattaggct
    23281 tgatcggttc acagcgacca ccgactttct gaacaaaaca cctaaccgct actgcgtgaa
    23341 aagttgactt gtacgaagtt taccttccat aagatcattt gtcaatgaaa aagaaaatat
    23401 tttttcattt ttctgaaaat tatttttata actttcacac acaagattat tttttactag
    23461 aaagtagcgc cctcttgttt ttttcttgct actatttctt gatgttcttg cttgattctt
    23521 tctaatagct ttggctcttt caacagatca agagctgtat tggcgagtag ttctgctgca
    23581 atcgcaatag aagcaaggcc tttgtcactt ttagcagcag ctttgaattc ttctgtgtgt
    23641 ccggcaatat atgtctcaga gattgctacc gtaggctgga ttgttggtat gacttggctg
    23701 acatttccta catcagaaga accgagactt gttctttgtt ccgtttctat ttcttcatct
    23761 ggaacacctg cttcttttgc atgctggaag aataagtcat caaaagaagg agtaacgatg
    23821 acatcatcaa ctgcattttg gaacaatcca aactcaaaag tcgtgcccgt acttatcgca
    23881 gcacctcgta cgatattttc cactttttca tatactttat ctaatgtttg ccgatttcct
    23941 gcacgtaaat agaaacgtcc agcagcgtaa tctggaatga cgttggcagc tactcctccg
    24001 tctgtaatga tcccatggat attgacatct tttggcaatt gcaagcgtag agcgttgatt
    24061 ccattaaaca cttggatcaa tgcttccaaa gcatttactc ctttttcagg tgctgctgct
    24121 gcatgggaag cgacaccgta aaatttgatg tcgactggat cattcgctaa agattctgtc
    24181 gttttcccat aacgaaaagc tggatggacg cataacgcta catcgacatc ctcaaaaaaa
    24241 ccttctcgaa caaagctgcc tttagctgat ccgttctcgc ccccttcttc ccctggggtg
    24301 ccatatacac ggatttctcc accagtttca tcaatgaatt gcttcactat gctggcggct
    24361 aatacggagt aagtaccaaa caaattatgc ccgcatgcat gaccaatacc tggtaaagca
    24421 tcgaattctg ccaaaaaggc aattgtggga ccgggtttat tggaaatata acgtgcatca
    24481 aaggctgttc ggtgtccagc tacttctttt tctacccaaa acctttcttt ttctaattgt
    24541 ttaatcaacg ctgctgagga ataaaactca tagttactta cttcaggatg ttcgtggata
    24601 tctagagcaa gtgcttgata ttctggtaaa cgatattgga ttagatcctt caattggttt
    24661 gttgagattg ttgttgtcat aaaaaattcc tcctatgcta gtcatttttc ttattttctc
    24721 ccgaatgttt cccatgcagg cacgcttgat ccttttgatg ttttctcgat tactttgact
    24781 gtgtcttctg tttgataagc gtctactatt ttttgatacg ttttattgtt ttcatcttct
    24841 tttcttgcaa cgatgatatt cacataagga cgtgcatggt catccactgg ttctaagaag
    24901 atggcatcag aagcaggatt aaatccagca tctacagcta caccgctatt gatcactgaa
    24961 atgtctacat ctgacaaagc acgtgctgtt tgggaagcat ctaattcaga aatgtctaga
    25021 ttttttctat tctcggtaat atcagaaaca gtgggcgctt gtccttttgc cttatccact
    25081 ttgatcaatc cagcagtttg caataacaga agagctctgc cgccatttgt aacatcatta
    25141 gggattgcta cttttgctcc gtctttgata tcagctacat ccttcaaagt gttagaataa
    25201 attcccagcg gtgcattgac agtatttccg atcgatacta aatcagttcc gtgttcttta
    25261 ttgtaattgt ctaaaaagaa ttgatgttgg aaagaattca aatcaatcga tccatctgct
    25321 aaagccacat ttggttgatt gtaatctgta aatttcacgt attccaaatt aatgttctcc
    25381 tttttcaaac ggtctttcac gttgtcccat acatctgtat cttctccaat aatccctagt
    25441 tttacgatag tttctttttt gtcagttgta tctgcttttc cttggctaca ccctgccaac
    25501 caaataattg ctacaaatgt aatgactaca aaacgaataa tttttttcat tttttctcct
    25561 ccactttcaa tgtgtaattt ttttaatcag ttgattactg ataaattgac ttaaaaaaac
    25621 taagattaga atcaataatg tagccacaat cgttacatct gtttggaatc gattataccc
    25681 tctcgatata gcaagattcc ctaatccgcc tgcacctact gctccagcca tggtagtcag
    25741 tccgatcacg ttgatgatag tcaacgccga gacccgaatg ataccaggca aaccttctaa
    25801 caaatacaca cgtaaaatga taccgattgg actggttccc atcgcttctg ccgcttcgat
    25861 caccccagga tcaacttcta gcagtgcgtt ctcgatttga cgagcaaaaa acggaacaac
    25921 tccaaaaatc aatggcacta aagctgcttt cgcaccaatc gtcgttccaa ctaagaaacg
    25981 agtagtcaat gctaaaagag aaagcaagat aatgaaaggg atggaacgaa tgatattgat
    26041 cagcttatca agtatttcaa atagcagacg gttagctagt aatccattag ggcgtgtcac
    26101 tactaacgtc acacctaaga tgattccaat catcccgcca atgaatgctg tccaaaaaga
    26161 catatatagt gtttgcttcg tcgcttcgac aaattcatcc ggaatcaaat aaacattggg
    26221 caaatatgtt ttaaagaaat cagtcatttt atcttcctcc ttcgatcact ttgatacgac
    26281 tatctaaatc gtttttttgt aaaatattta tttttacacc agatttgatc aaataatcca
    26341 atgctttttt ccgctgtttg gtttctccag ctaaagtaac gatcaaactc cctaacggcg
    26401 tttcttgtaa taactctaca ttgccatata aaatattcgc tgttacttga tatttgctgt
    26461 acagatgagc gattagaggt tcgttcgtct gatttccaat ataacttaat tccaccagcc
    26521 atttattggc gatctgatcg gcaaaagcag aatgggcaat gatcgtttct aatgcttggt
    26581 caagatgagt agctgttcga ataaaatctt tggtcaattc ttcttcagga ttgctgaaga
    26641 tctggatgct gctacctttt tcaacgattc ttccatcttc cataaccgct accttgttgc
    26701 agatttcttt gacaacttgc atctcatgag tgatcaggac gattgttaaa cctaactggc
    26761 gattcaattt ttttaacaat gcaaggatct gaagggtcgt tttcggatca agtgcactgg
    26821 ttgcttcatc acataataat accttaggtt cattcgccaa agctcgtgcg attgctactc
    26881 gttgtttttg tccccccgac agttgtttag gataagcaga tgctttttct tccaaaccga
    26941 caagttccag tagttcattc actttttgac gacgttcctg tttcgatttt ccagaatact
    27001 ttaaagaaaa atcaacgttg tcaaaaatag ttcggctttc cattagattg aaatgctgaa
    27061 agatcatacc gatggccttt ctttcttttc gcaattcttt gggagagagc tgactcagat
    27121 tcgtctgatt gacaatgact tctcctgctg ttggtttctg cagcaaattc atcacacgaa
    27181 ctaacgtact tttccctgca cctgagtaac cgacgattcc ataaacatcg cctttttcaa
    27241 tcgttaaatc tacagaatct actgcctgta tctctttttc tttttgtttg aaacatacag
    27301 aaacatctcg caattcaatc attaaaattc ctccttatct aaaaaaagcg tcctcaagaa
    27361 aatgaaaatg tcattttctt gaggacgctt ttttgcgtgt taccacctca tgttcaagct
    27421 gtgttcacac acaactcctc ttcaagtacg atcatactct agcaagatat cggtcgcagc
    27481 cgtcatcgcc ttacatctat gctcgggatg aattgctcga tggccatttt ccaatagtcg
    27541 ttccttgctt cttctcagct accgaagctc tctgtcaaag gttcttctat cgtacttacc
    27601 atttcaatgc aaataatatt caaaaaaaaa gtccttttac taacataaac tatgtcagta
    27661 aaaggacgac gtatcgcggt accacctttt ttcggaagtt tccttccctc aagcccaaca
    27721 tctcaaaaag agagattggc gttcgtttta acggtcgaac agttccgaat ttgcctactt
    27781 atcgacaaat tattctccaa ggccattttc agcttttctt acttgactct tctcaccagc
    27841 cagagcctct ctgcaaagtt tccaaactta ctttcctttt caacgaaatc gatattttgt
    27901 tgttgggatt aatctacatg aggaaaactg aaaagtcaag tacgaaattc aaattatttt
    27961 ttctatattt atttttctgt ttttttattt aacatttcaa taacagttcg aagatctttt
    28021 ccttccgcaa gaagtttcaa tttttccttt tcttcgacgg tataatttcg gacaaaactg
    28081 gaatcaggta tcaaaacaac gcctaatcct gctcgtgaag cagctgttgc tcctactaaa
    28141 gaatcttcca ctgcaaaggc tgaactagct tctaatcctg ttcgttccaa agctgtcaga
    28201 taaggaatcg gtgaaggctt gttctccgac acttcgtctc cgaatgtaaa cgtgtccaag
    28261 taatcagcta atttaaagtg atccaagata tctgttgctc ttttcgtaac agtggtcgta
    28321 gcaatgccta gtttcatatg acgttctttt aagtctgcca atatttcttt tgcatatggt
    28381 tttaagtgga tggctccgct tgtcagctgt tgataaaaat attcttcacg cttcgctcgg
    28441 acttcctgta ctttttcagg gctacctgct gctttcacta aaatatcaaa actttgtttc
    28501 cagttttttc cgccccaagc gtcaacgatt tcttttggga tatggatatc aaattgctga
    28561 aatccccaaa gccagccatc acgatacgtt ttttctgtgt caactaacaa accatctaaa
    28621 tcaaatattg cacctttcat ctatacatta atcctttcca aaacaataca catagtttag
    28681 cacgactggt ccaaaaagaa cagaagcaaa gaaccagcct tctcgtttat aagagttctt
    28741 ggaatcgacg gatatagatt ttcttcacag ctgtcacaag cgccagataa gcgatgactg
    28801 tagcaaataa ccataaccag taattgccag gaagtggcat caagcctaat tcagcaccaa
    28861 aacttgtaaa aggaaggaca gaaccgacaa taattcctaa tgtagtgata acaaacatgg
    28921 caaatgttgc gttgctttgg ataaatggta ctttcggtgt acgcagtgca tggagcacta
    28981 aggtttgtgt ccatagtgat tcgacaaacc atcctgcatg gaataatgcg atgaaaatca
    29041 ctcgctgtga actatccaat gtatggaaac ttccgcccac tacagcagga caaataacaa
    29101 aatacatcaa caagtaagta gtaatatcaa atatcgaact tgttggacca aagtaaacca
    29161 tgaattcccc aatactagat gcattccatt tttttggctc gtccaaatat tctttatcca
    29221 tccgatccca tggcaaggaa atgcaggaaa catcatagat cagattcaaa aacaaaagtt
    29281 gtaaaggcag cattggtaaa aatggcagga acgtacttgc aatcagcacg gaaaacatat
    29341 tgccaaaatt agaacttgct gtagccttga tatatttcat gatattccca aaagtttctc
    29401 gtccagaaag aaggcctctt tccaaaatcg tcaaatcttt ttctaaaagg atcacgtctg
    29461 cagattcttt cgcaatatcc acagctgtat ctacagaaat accgatatca gccactttca
    29521 ttgcaggagc gtcattgata ccatctccta aaaatccgac agtatgacca tttttacgta
    29581 aagctgtcgt caaacgtgct ttttgctgag gattcaattt tacgaatact tcatggtctt
    29641 cagctacttg tgctaattca tgatcactca tttccgagat tttctcaccg gtaaccaatt
    29701 cattgatctc tagacctact tgacggcaca ctgaacgtgt aactaattcg ttgtccccag
    29761 tcagaacttt tacagctaca ccatgttctt tcagagcttt caacgcttgt ttcgttgttt
    29821 cttttggtgg atcaaggaaa gcaagataac caatcaaaac catgtctgac tcatctttga
    29881 ctgaaaattc tccaacgacg cttggattgg tcttttgtgc gacaccaatc actcgtaagc
    29941 catcttcatt aagtgactgt acttttgcaa gtacggcttc ttttcgttct tttgttaatg
    30001 gtgtaacagt accgccaaga tcaataaatt tagaaatgtt cagcatttct tcaatcgcac
    30061 cttttgtgat catttgtgtt ttaccagctg gatcagcaac cacaacactc atacgacgac
    30121 gttcaaaatc aaaaggaatt tcatccactt tttgataatt gatcttatct gtatctaaag
    30181 tttctgttgc ttcatcaatg atagccacat ctaacaaatt tttcagccct gtttgatagt
    30241 agctatttag atacgcatgg cgcaaaacac gatcatcttc atttccttca caatccatat
    30301 gatattcaag aatgatttta tcttgtgtca atgtccccgt tttatccgta cataacacat
    30361 cgattgcacc aaagttctgg atggcattca aatttttgat cactgttcct tttttggcca
    30421 tcacacttgc tcctttgacc aaattcgtcg taacgatcat tggaagcatt tcaggtgtta
    30481 gaccaactgc tacagatagt ccaaaaagaa aagcttctag ccaatcccct tttgtaagcc
    30541 cattgatgac gataactgct ggagccatca atgacataaa tttgatcagt agcatggatg
    30601 ttttatggat gcctaattca aagcttgatt gaattggttt ttcagatagc gtttctgcta
    30661 catgaccaaa tagtgtttca tttccaacag aaacaatgat tccttccgca cttccactga
    30721 tgacattact tcccataaag acaagatttt cgtaacttgt ttcgctttgc tgatcgtctt
    30781 cacatacttt cgcatgcttt tctactggat agctttcccc tgtcaatgct gcttgggaaa
    30841 tgaataaatc ctttgcggac aataaacgca tatccgctgg tatcatatcc cctgctgaaa
    30901 gccgaacaag atctccacag acgatttctt ccataggaat ctctgtgtac tttccattac
    30961 gttttacagc tgccgttact ttcacaagtg atttcagttt ttcagccgct tgattggaac
    31021 gtacggactg aatcaacgtc attgtcccgc tgacgataac catagtgaag ataatggcta
    31081 caccgaaaag atctttatct ccaggagctg ctaatacata ttccgtgatg aatgaaataa
    31141 ttcctaatgc gatcaacact aatgtaaatg gcgtgatgta tgctttcaat atttctacaa
    31201 tgaatggtgt ttttttgcca tatgaaatcg cattttcacc gtaattttct cttgaacgtt
    31261 cgatttgttc ttctgtcaat ccatttgctg atgcatggaa tagttcaaat aattcttgtt
    31321 tcgtttttcc agcaaaagct gcatagattt tttgtgtatc tttctttttt tccatctcaa
    31381 tctctccttt gtgtccaaaa gacagctgtt ctcgctgctt ttggtcttta gctattcatc
    31441 ggatcgatag agaaaaaact gaaaggggct gagaacagat agataatagc cctggccttt
    31501 cctctagatc cttgtttttc gaatgactgt catccatttg ttctcatctc ctttactaag
    31561 taattttaat tcatgacttc caatcatttt tcgaatagtt atttttccaa ttagaccacc
    31621 tcctttttat ttttcaccga tggggatttg cggcaacaaa aaaacctctc gccaaatact
    31681 cagcgaaagg tttgaaaaag catattaaaa aaagcttctc agatctcatc gttgagtttt
    31741 gacactgtac aacgtaaaaa gcagatacct gcttttagct accttatgaa aagccttatc
    31801 tcgacaattc ctgttctacc cattggcgtc tctcgacgtt tttgggcagt agcctatgtt
    31861 tgtataggag cctcacctaa caaatcttat tcggttttcc ttcgttaata taacaactaa
    31921 aaaagaggat gtcaaatcaa ttttccatgt ttttcatact ttttttaaaa tacacacgtt
    31981 atattcctgt ctcacgcggt tttatttgtc tcattttcca cctcccgcta taatagaaat
    32041 atagtaggaa acgaggtgct gttatggaaa gaacacttgt tattatcaag ccagacggcg
    32101 tgagacgcca tttagtcgga agcatcatcc aacgttttga agcaaaggga ctggccattg
    32161 ctgaaatgaa gtttgaaact atgactcctg aattagcaaa agaacattat cagcacttga
    32221 ctgagcgcag tttttttgat gaactgatcg attacatgac ttccggtcct gtcgtttatc
    32281 ttgtgctggt cggcgaggaa gtgatcgata tcgtccgtaa gatggttgga gcaacaaaag
    32341 ctgccgatgc tgttccaggt acgatccgag gagactacgc gctgccgggg actgaaaaca
    32401 tcattcacgc ttctgattcc cgtgatgctg cggtaaaaga gatcgcccgc tttttcccgc
    32461 cattcgatat aaacaaaccg tctgaaaaag cggcgaagtg atacaaattc taaactgctg
    32521 gtctagttgc tgggttcagc aatggccagc agttttttct ctaaggacct ccgttgattc
    32581 tttcctaaca tatattcgag cactgtgaag aattcttggt agtctttcgt cttttcttcc
    32641 cctaaagcag cagaaatcaa tctttgataa taatctgcca tcaatgtttc atagatcact
    32701 gtacttcttt ctttatgtgc taagctccgt ttcatatctt cattcacact acgtgccttt
    32761 ttcaaccgac cattttctat ataaaacgaa gtcaggttca ttaaaaaagt aaagagatac
    32821 tgctcatgat tgttcaactg tgctaatcgt cgcattcttt ttttgatttt caaataattg
    32881 ttctcaatga accgatcact gaatatccaa ggaaaatcag ctagaataga tagttcaaat
    32941 tgaccatagt ctggtatctg catcaagtat tcttcaatga ttcggcattc ataacgtaaa
    33001 aattcaaatt ctgtctcaga tacttctgtt ttttcgacca tgtgaagatt caaaaccaaa
    33061 taatacagat cttctgtttt cttaaaatgc ctacggttat tgctgatctc tttataagga
    33121 tcaaagctgt cttcttgtac ccgatctagc attcgtcttt ttttctttaa ctttattggt
    33181 tcatccagct ggtttcgcat ccattcatat tctgcaagtg tcatgttcat tcgctctaaa
    33241 aatgatctca atgttacaaa tgacattttt ttcactgaat ttgtctcaat cccgactaga
    33301 gaagtcttaa aacagattcc ttccgctaat tgggactgtg tcaacttctt gttgactcga
    33361 agtttcttga tcaattcacc atcatacata atagttctcc tttttaattt aaatttttcc
    33421 acattcaata aatagatacg ttaaaaagga aaaatacacg aaaaaaataa aaaaatgttt
    33481 ttttcataaa aaataccaac cttcaagcat tagaatgttg tctaactact gaaggttggt
    33541 ttgattgttt attgattatt tttttgctgt tcaacgtctg ttcttgttac tggatataag
    33601 ttggttgttg ttttattacc attttttgaa aagacacttg tcgaatgttc gcctttttgc
    33661 ttttcgattg cttcattacg ttccgcttca tttttatagt catatttttt cggatcaatc
    33721 gtctcaaatc cgtttggcac ataaaaccgc aagagatttt cctgattcag cttatctgaa
    33781 agacttaacg cagtcttgac tttttcctga tctttggaga tttcctcatc gattcctgct
    33841 gctttcgtat cgatgatttc tcctgtctga ttattgtaag cttttcctcc taggacggtg
    33901 tatttgggtg tcacaaagtt cccatttcga aaagcaacta cttgatcatg ctgagaagat
    33961 aataagtctg taccaaaatg aagataatct ttatcatcga ttcccaatag atgtagtaat
    34021 gtcggcaaaa catcgatttc tccaccgtat tcatgattga ctgtcccttt agtataacca
    34081 ggcatatgga tcatcaatgg cactcgttgc atctgtgcgt tgtcaaattc atcccatgta
    34141 tctggatctt taccaagagc gcttgctaaa tctttattat ctgtattcga gatcccaaaa
    34201 tgatccccgt aaatcacaaa gattgaattt tggtaaatac cagatttttt caaatacgta
    34261 aaaaattgtt ccaatgattg atccagataa tgtgccgttc gaacataatt atctactgtg
    34321 ctattgccag tattcaaaga tggaaagtcg aaattcttgt catccgtata ataaggcgtg
    34381 tggttggtta cggaaagaaa tttcgtgtaa aacggctgtt gtagatgctc aagatattgg
    34441 gcagattctc tgaataaatc tttatctaat atcccataac ctaacgtttc gtcggattca
    34501 tcaaaataag atcgatcaaa gaaattgtca taacctaagt ttttatatac atgatctcta
    34561 ttccaaaaac tagctacatt cccatggaaa acagcgcttg tatagccttg cttttgtcca
    34621 aggatcgctg gtgcggcttg aaagacattg tctgacccaa gttctgtgaa taatgagcct
    34681 tgaggtaaac caaatgtgcc agtttccaac atattttcag catcacttgt ctttccctgt
    34741 cctacttcat gaaagaaatt gtcaaagctg atcgttgctt gattctggaa aatactattt
    34801 aaaaacggtg tgacttcttg tccgtctacc ttcatattaa tcaaaaactg ctggaaactt
    34861 tctaaatgga gaacgatcac atttttccct ttagcgatcc caaatgtttc gggatttggc
    34921 tctgcataat gtttctttgt ataatctaaa acttcatcaa tcccattact gcttgcatgc
    34981 gcgcgaacac tgctagtcat tcctgttttg attccgtcat aaatagtata cgcatcgatt
    35041 cctagatatt tgacaatata tgaacggtca aatgttcgct gcagcaattg tggacggttg
    35101 gcttcgctca gcgctagatt tcctgaaaaa ataagccctg aaagacaggt aacagcgata
    35161 gccatcggtt tgccgacagg gttgcttttg ataggtattt tcttgacctt caaccaaacc
    35221 agtagcccaa tgaacacagc gatatccagc cagtagatga catcatgggg cttcatcaaa
    35281 gaaaaggagc ttcctgacaa tccttgcgac actttcgaaa agcctaatac agatttgact
    35341 gtaatgaaat ctgtgaattc ccgataaaaa ataatattca agtacaacaa aagcgtattt
    35401 aaaatatcaa tgatcaaaag aatagctaac gctggctttg gctttttaat atacaaagaa
    35461 aggccaaaaa acaataaggt agtcgcaatt gggttgatcc acaagataaa gtactggatc
    35521 gtaccttcca cacctaatga aaaatctgca tagtaggcaa tgatcgtctt cagccagaaa
    35581 aagaaaacag ctgtcaaaac gattgctaaa cgattttggc acaatttttt aagttgtgtc
    35641 acgtatatca cttctctcta ttcacatttt ttcttatttt gctcctgaaa aatgaaaatt
    35701 tcctaaaaaa gttgttatct taagattttt ttattctttc taaagattat tccgtccact
    35761 tttcacagca taaaaccgct gcgatgtaag cgattaaact aatgaagaga taaaagtctt
    35821 gtggtgaccg cttcactcca cggtattcaa aagccagttt ctcggtattc gtacaaaaaa
    35881 agaggctgtg acaaaattct tgtcgcagct ccttatttct tgatgcagga cagctttttc
    35941 acaacttctt ccttaaacgg tgttctcctg ccaactcctc ggccacaagt cacaatattt
    36001 ataaaacatg agaagctgtt ttttgaaatt gttccttgtg gctcagagtt aaacggcagg
    36061 ctcaagacct cttgatacac ggtgttcaat cagctgaccc tcggtattag attatgtcag
    36121 gacgctaatt ttacaacctc ttggtaaacg gtgttcaaaa gcttgcatct gcggtaataa
    36181 gcccaaccaa acgaaaaata taaggagcta ttttttgaaa ttgctccttg tggctcagag
    36241 ttaaacggca ggctcaagac ctcttgatac acggtgttca atcagctgac cttcggtatt
    36301 agctcaaaaa acggcaaaat atgaggaact attttgccgt ttgtttctct aatactcagg
    36361 tcaaaacgct gatttcacaa cctctgtttt tcattgtcca taggattgat attgtccttg
    36421 tgatgactca ttcgtaataa ttgaggcttg attttcttca cttcccgtta tcgtttgtcc
    36481 actgccagaa tctgaaggac ttgttcctgt cgactcgttt ttttgagaag agacagttgt
    36541 tttcttgact tgttcatttg tctttttcca ttccgctaaa cgatcggcga ccactttttt
    36601 gtctactttt tcagaataag cggtgatcac ttttccattt ttcaaacggg ctactttgtc
    36661 gccatcatga gtcaaaagca aaacggtcaa atgcttgtct ttaaattgat attgtctgag
    36721 agaaatcgca ctaagtacgt catcgatatt aataaattga ttttcttctt ttccttttgg
    36781 caaataaatg tccaattcgc ctttttcgta attggcagtt attttatact ccgcccacca
    36841 ataagttgag aattcttttt tgaaattatc tactgattct ttgcttgcta cgattttttc
    36901 tgtttctttc tgagcaagat ctgctgtcat ttttcctgaa aatgctgcgg ataaaataag
    36961 cagtaagaaa aaaccgaata accaaaagag aagaaacggt ctttttttcc tcatgctttc
    37021 ctccactcct atttaatttt gactattcta ttatatacaa aaaatgaaat agaaagacaa
    37081 aaaagttgaa aaagatcgta aataattgaa cttctttttc acaaaatggt aagaatggag
    37141 aatttcacgc atttgctctc aactattctt tcttaagcct caaatccgtt tttatctgat
    37201 acgtctttga accaatgacc cgattttttg attgttcttt ttccatcttg tgctaagtct
    37261 actgaaataa agccatatcg attcttatat gcattggtcc acgaccagtt atccatacat
    37321 gtccacatat gatagcctaa acaattggca ccttcttgaa tggcttgatg gacatatttc
    37381 agatgagatt ggacaaattc gatccgataa tcatcgtgga tcatgccatc ttctttgata
    37441 aatcgtgctt cgttttctac acccataccg ttttcagaaa taaagcagtc gatatttcca
    37501 taatgatctc gtacattgat caaaatatca tagattcctt gttcatagat ctcccatccg
    37561 cgataaggat tcattttacg accaggcatt tcataattgt cgaaataatc ctcaggcatt
    37621 ggaccgtttt tagtatcgat tggtgtttct tttgctttta cccggcgtgg ctggtaataa
    37681 ttgataccta aaagatctac tgtattttct ttgataaccg tcaaatcctc tgcatggatc
    37741 acaggcatga gatcaagttc ttttactatc tcaatcaatt cacttggaaa ctcgcctttt
    37801 acagctggat caaggaatga acgattgaag aacgcatctg ctatttgcgc tgctttaaca
    37861 tcttcagggt ttgattcgtc tcttggatag cttggtgtca gattcaagat gataccaata
    37921 acaccacctt gctccatttc atggtaagat ttgatggcta acgctgaagc caacgcttca
    37981 tgatagccaa cttggatcgc ttttttcata tctgactctt ctggataatg ccatcgatat
    38041 aaataacctg cttcgactgg aacgattggt tcattatgag taaaccattt ttttactttc
    38101 gaaccaaaca attcaaaaca acttttggca tatttttcat aggcttcaac cgtttctcgg
    38161 ttcaaccatc cgcctttttc ttgcagatac atcggcatat cgaaatgata cagattcaca
    38221 aagggttcga taccgttttc aatcaactca tcaaaataac gatgatagaa acgaacggct
    38281 tcttcgttga ttgttccaga ttcatcaggt atcaaacggc tccattggat agatgttcga
    38341 aatgaattat gcccagtctg tttcatcaac tgtacatcct cttgatactt cgtataaact
    38401 tgcgaggttt tttcaggtcc tacttgatca aagaactttt gcggttcttt tttgtaccaa
    38461 taatcaaaaa tgttctctcc ttttccatcg cctgaaatcc ttccttctgt ttgtgggcca
    38521 cttgctgcag aaccccacca aaaatttgct ggaaattgat attttttcat caaagcacct
    38581 ctttttcttt tttagttcgt tttagttgat tccatgtatg atattttcca tcacaatcac
    38641 tttttcattt tcttcctctt cttttttgat tcgttttaac agctgttctg ctgctcgttc
    38701 cccgatttta tctgttggtg gcgtgatcgt gattttcgga aggatactca gatcgttttt
    38761 atctaaataa tcatagtgac tgaacgcaat atccttcccg attctgacac cttcttgatt
    38821 gaaacattcg atggcaccaa tcgacatatt gtaattgctg acaaaaatag cagttgcccc
    38881 tttttctaat aatgcttttg ccccgtaata gccgcttttt ctagaatagt ctcctgtaaa
    38941 gacctctaat tggatcgatg gatcattttg gaccgcttct ttggctcctg ctaaacgttc
    39001 tcttgctacg tagtctgttt gagtggcagc aataaatccg atttttttat gtccttgttc
    39061 accatgatga gcgatcactt ttgctacact ttctcgatca ttcactaata ttgtatcaat
    39121 acctgctggt ccttctggac aattcaatgc gataactgga atactcattt ttgtgagcat
    39181 ttcaaatcca gaccactctt cttcggataa gaagacaatc agcccatcga tcacatgctt
    39241 catcaggtat tcaatttttt gttcaatttt ttctggctga tcggcaaacc cgcttaataa
    39301 taagctatac ccattttctt cagctactct ttcgatccct gagacaactt ccgacccaaa
    39361 acggctggaa atcccgttta tcaaaagtcc aatagagaag cttcgattat tcttcaaccc
    39421 tttagcaatg atgttttctt tatagtccaa cgctgaaatc gcttctgcta tttttttcat
    39481 gttcttttcc ttcagttgct gaccattcaa gtaacgggaa actgttccca ctgaaacacc
    39541 agccatctta gccacatcac ggatcgatgc catacattct cactcctgcc agttacattt
    39601 gatttctctt tcttgttgtt cgattatgat gaccgcattc tttgcatagt gttgcttgtc
    39661 atcaatatcc atataactaa agtcttcagt agagcaactt cctctcacta ttaattatac
    39721 ttaaacaagt atttgaaccg gttcattttt aatatagcat ttttttaaaa gattgcaaca
    39781 cttttttaaa acgctttctg aaagtggcgg attttttgcc tttttaaaat tttattctaa
    39841 aatttactct atttgtgggt gttttgtgcg tttttctctt ccatccgttt gaagttttac
    39901 attccaatgg tataatttct ttatcctatc aaatggggga agtattttga agaaattaat
    39961 cgtactattt attttgtctg cgggactttt gacattgact ggctgtgatt tgtttggcgg
    40021 ctctgaccaa tcctcggacg aaacaaccga ttcttctgtc ttaaaagcgg aaaaagcaga
    40081 taccaccaac agtgtatata cgctaaaagt acgtaaagat atggatttat ccgcgggaca
    40141 gttgacattt acagataaaa aaatggaatg gacacgcacg tatcagacac aaggaactga
    40201 ttcttctgaa tcatctgaag aaaaaacagt gctgacagat atcaagatca ctaccaaaga
    40261 tgacgaatat attatttcag gaaaagaaaa taaaaaagaa acaacagtca tatttacaaa
    40321 aatcggtaat taccgtttga aggatgagga tggcaacatc tacagtctat agtgccgtct
    40381 gttggatctt cttttgtttc tccccttctt ttctgctata gtaaagaagc aagatgattg
    40441 taaaggagac gaaatggatg atcgatagtc ctgattattg tacatgtaat aacaacaaaa
    40501 atatccatac agaatttaat gaccaaggaa gcttgagcat atgcgacaac tgtcacaaac
    40561 tagtcaaaga ttcatttaaa acatttgaat cttatcctgt tcaaaattat gtaaaaagta
    40621 gaagaagata aacaaatcca agcaaaactc actatggctg atttttatga acttcaaact
    40681 cagcttcttc ctttgatcaa gcttcatcag taaaacaaac agtggatcat ttcagtttac
    40741 aaatcaaaga gtaaagattt atttatttca aatatttgaa tataaaataa ccaaacgata
    40801 gaaaggctta ttctacatca cgtagtaatt
//
LOCUS       DADQDV010000020        40386 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.020, whole genome shotgun sequence.
ACCESSION   DADQDV010000020 DADQDV010000000
VERSION     DADQDV010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 40386)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40386)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40386
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.020"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..109
                     /locus_tag="J8S10_001109"
     CDS             <1..109
                     /locus_tag="J8S10_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002606082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAZ9629707.1"
                     /translation="YIPIKDIILHFEKYDYRFHWNSDNSVIEIWIPIQD"
     gene            237..1451
                     /locus_tag="J8S10_001110"
     CDS             237..1451
                     /locus_tag="J8S10_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAZ9629708.1"
                     /translation="MNDKNFIEELRQKREEYGVTQTRLAVACGISREYYNRIEKGKQP
                     LNDELREIIEKQIERFNPQEPLFLLIDYFRVRFPTTDALAIIRDVLQLKSNYMLYEDY
                     GKYGYESKYVLGDINIMCSMQEHLGVLLELKGKGCRQMECYLLAQERSWYDFMLDCMT
                     AGGVMKRLDLAINDKAGILDIPKLKEKYKAGECMSYFRMQKDYSGTEKCGSDLPKNTG
                     ETLYLGSTSSELYMCAYQKNYEQYVKNGTEIEDTEIKNRFEIRMKNERAYYAVVDLLT
                     YRDAERTAFSIINHYVRFVDREDDKPKSQWITNDDWAWFVGENREPIRLTTKPEPYTL
                     QKALHWLQRQVAPTIKMVQALDRENRTTILKDMIEQAELKDKHKHLLQLEKSTIEERI
                     DTAVPQENDGIF"
     gene            complement(2161..2349)
                     /locus_tag="J8S10_001111"
     CDS             complement(2161..2349)
                     /locus_tag="J8S10_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008787514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629709.1"
                     /translation="MAVREYHYLTVQVMAIKEDKSFTRTQIGFRSLLQGKGRGVFVST
                     ASCLSNVLNSFIQLSKND"
     gene            2440..2649
                     /locus_tag="J8S10_001112"
     CDS             2440..2649
                     /locus_tag="J8S10_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008394616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA wybutosine-synthesizing protein 3-like
                     protein"
                     /protein_id="HAZ9629710.1"
                     /translation="MNCLERFYRKGVCVIDNAVKTIQKKNGKCGIGNRGKTKIVVKEH
                     FSEKGKTMEELLTDVMLEKAKQTIA"
     gene            2761..4374
                     /locus_tag="J8S10_001113"
     CDS             2761..4374
                     /locus_tag="J8S10_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003019515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4368 domain-containing protein"
                     /protein_id="HAZ9629711.1"
                     /translation="MKQQIYNTALYLRLSRDDELQGESSSITTQRSMLRLYAKEHHLN
                     VIDEYIDDGWSGTNFDRPSFQRMIEDIEAGKINCVVTKDLSRLGRNYIMTGQYTELYF
                     PSHNVRYIAIDDGVDSEKGESEIAPFKNIINEWVARDTSRKVKSAFKTKFAEGAHYGA
                     YAPLGYKKHPDIKGKLLVDDETKWIIEKIFSLAYQGYGSAKITKQLRAEKVPTASWLN
                     FTRYGTFAHIFEGKPESKRYEWTIAHVKAILKSEVYIGNSVHNMQSTVSFKSKKKVRK
                     PESEWFRVENTHEPIIDKEVFYRVQEQIKSRRRQTKEKATPIFAGLVKCADCGWSMRF
                     GTNKTNKTPYSYYACSYYGQFGKGNCSMHYIRYDVLYQAVLERLQYWAKAVQQDEEKV
                     LNKIQKAGNAERIREKKKKASTLKKAENRQNEIDRLFAKMYEDRACEKITERNFVMLS
                     SKYQKEQIELEQQITSLREELSKMEQDMIGAEKWIELIKEYSVPKELTAPLLNAMIEK
                     ILIHEATTNEDNERIQEIEIYYRFIGRVE"
     gene            4409..5620
                     /locus_tag="J8S10_001114"
                     /pseudo
     CDS             4409..5620
                     /locus_tag="J8S10_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
     gene            5643..6569
                     /gene="glsA"
                     /locus_tag="J8S10_001115"
     CDS             5643..6569
                     /gene="glsA"
                     /locus_tag="J8S10_001115"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HAZ9629712.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            6777..8237
                     /locus_tag="J8S10_001116"
     CDS             6777..8237
                     /locus_tag="J8S10_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629713.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIREIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            8458..10221
                     /locus_tag="J8S10_001117"
     CDS             8458..10221
                     /locus_tag="J8S10_001117"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HAZ9629714.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            10305..10763
                     /locus_tag="J8S10_001118"
     CDS             10305..10763
                     /locus_tag="J8S10_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HAZ9629715.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            10872..11555
                     /locus_tag="J8S10_001119"
     CDS             10872..11555
                     /locus_tag="J8S10_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HAZ9629716.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIIDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            11702..12316
                     /locus_tag="J8S10_001120"
     CDS             11702..12316
                     /locus_tag="J8S10_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HAZ9629717.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            12332..12538
                     /locus_tag="J8S10_001121"
     CDS             12332..12538
                     /locus_tag="J8S10_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629718.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            13079..14209
                     /locus_tag="J8S10_001122"
     CDS             13079..14209
                     /locus_tag="J8S10_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HAZ9629719.1"
                     /translation="MGPYLTLSMIGLLEVYSASSYRLLQADENTKSLLLRQLIFIFLS
                     WSVIFLARSVKLHYLLHPKIAGYGLALSIFFLVLVRIGIFGVTVNGAQRWISLFGIQF
                     QPSELANLFLIFYLSWFFRDGNSSPKDLKKPFLITVGITFLILFQPKIAGALMILSIA
                     WVIFWAAAVPFKKGIYLIVTFSALLIGAAGGVLYLGNKGWLPQMFNHAYERIATLRDS
                     FIDSHGAGYQMTHSFYALYNGGIFGRGLGNSITKKGYLPETETDFIFSIITEELGLIG
                     ALCVLFLLFSLCMRIFCLSSRCKNQQAGLFLLGFGTLLFVQTIMNVGSIAGLMPMTGV
                     PLPFVSYGGTSYLILSLGIGITLNISSKIQAEELALYRPEKQ"
     gene            14301..15056
                     /locus_tag="J8S10_001123"
     CDS             14301..15056
                     /locus_tag="J8S10_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HAZ9629720.1"
                     /translation="MKVSQKIILSILLLLTLVVGYFSIEFIHGFSSAKQSSTVKKVEP
                     KSIPTTLNVALIGSDARSKDENGRSDSLLVAQYNQKTQQAKLISIMRDSYVDIPGYGM
                     NKINAAYSYGGVDLLNQTLKENFKFEAPYYASITFQDFIDCVNELFPGGVKIDAEKSL
                     DLDGVYINKGEQVMDGNTLLQYARFREDKEGDFGRIRRQQQVIKAISQQLKDVTSIFK
                     LPKAVGKLLGSIQTNLPESVLLDCGMDFLKDIC"
     gene            15114..17153
                     /locus_tag="J8S10_001124"
     CDS             15114..17153
                     /locus_tag="J8S10_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HAZ9629721.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKMITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSYQVTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(17262..18413)
                     /locus_tag="J8S10_001125"
     CDS             complement(17262..18413)
                     /locus_tag="J8S10_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HAZ9629722.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(18567..19097)
                     /locus_tag="J8S10_001126"
     CDS             complement(18567..19097)
                     /locus_tag="J8S10_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629723.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(19196..19546)
                     /locus_tag="J8S10_001127"
     CDS             complement(19196..19546)
                     /locus_tag="J8S10_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HAZ9629724.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(19703..21232)
                     /gene="ahpF"
                     /locus_tag="J8S10_001128"
     CDS             complement(19703..21232)
                     /gene="ahpF"
                     /locus_tag="J8S10_001128"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HAZ9629725.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(21242..21805)
                     /gene="ahpC"
                     /locus_tag="J8S10_001129"
     CDS             complement(21242..21805)
                     /gene="ahpC"
                     /locus_tag="J8S10_001129"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003756453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HAZ9629726.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(21949..22611)
                     /locus_tag="J8S10_001130"
     CDS             complement(21949..22611)
                     /locus_tag="J8S10_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAZ9629727.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            22795..24441
                     /locus_tag="J8S10_001131"
     CDS             22795..24441
                     /locus_tag="J8S10_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HAZ9629728.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAVLLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPNMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDLQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            24432..25514
                     /gene="uxuA"
                     /locus_tag="J8S10_001132"
     CDS             24432..25514
                     /gene="uxuA"
                     /locus_tag="J8S10_001132"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HAZ9629729.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFGLPGWEP
                     ERLAPIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLA
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(25622..27175)
                     /locus_tag="J8S10_001133"
                     /pseudo
     CDS             complement(25622..27175)
                     /locus_tag="J8S10_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
     gene            27323..28464
                     /locus_tag="J8S10_001134"
                     /pseudo
     CDS             27323..28464
                     /locus_tag="J8S10_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(28590..29669)
                     /locus_tag="J8S10_001135"
     CDS             complement(28590..29669)
                     /locus_tag="J8S10_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAZ9629730.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(29772..30212)
                     /locus_tag="J8S10_001136"
     CDS             complement(29772..30212)
                     /locus_tag="J8S10_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAZ9629731.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(30269..30679)
                     /locus_tag="J8S10_001137"
     CDS             complement(30269..30679)
                     /locus_tag="J8S10_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HAZ9629732.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(30859..31293)
                     /locus_tag="J8S10_001138"
     CDS             complement(30859..31293)
                     /locus_tag="J8S10_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAZ9629733.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(31393..32241)
                     /locus_tag="J8S10_001139"
     CDS             complement(31393..32241)
                     /locus_tag="J8S10_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAZ9629734.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            32630..34396
                     /locus_tag="J8S10_001140"
     CDS             32630..34396
                     /locus_tag="J8S10_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HAZ9629735.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            34498..35757
                     /locus_tag="J8S10_001141"
     CDS             34498..35757
                     /locus_tag="J8S10_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAZ9629736.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            35904..37205
                     /locus_tag="J8S10_001142"
     CDS             35904..37205
                     /locus_tag="J8S10_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAZ9629737.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            37208..38059
                     /locus_tag="J8S10_001143"
     CDS             37208..38059
                     /locus_tag="J8S10_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAZ9629738.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            38072..38887
                     /locus_tag="J8S10_001144"
     CDS             38072..38887
                     /locus_tag="J8S10_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HAZ9629739.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            39038..40204
                     /locus_tag="J8S10_001145"
     CDS             39038..40204
                     /locus_tag="J8S10_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAZ9629740.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
BASE COUNT        13680 a         7034 c         7834 g        11838 t
ORIGIN      
        1 gtatattcct ataaaagata ttatcctaca ctttgaaaaa tacgattatc gttttcattg
       61 gaatagtgat aattcagtta ttgaaatttg gatacctatt caagattaga agcaatttta
      121 tatccataca cacaaagcag ttagtcttag gattgactgc tttttctata cagattttta
      181 atgacaggca attatcaatt atggtagttg ccttttttga ttggaggaat tgaagaatga
      241 atgataaaaa ctttattgaa gaactaagac aaaagcgtga ggaatacgga gtaacacaaa
      301 caaggcttgc tgttgcctgt ggtatcagcc gtgaatatta caaccgcatt gaaaaaggaa
      361 aacagccatt gaatgacgaa ttaagagaaa tcatagaaaa acagattgag cgtttcaatc
      421 cgcaagaacc actattctta ttgattgatt actttcgtgt ccgctttcct actacggacg
      481 cattggcgat tatccgtgat gtattacaac tgaaatctaa ttacatgctt tatgaagatt
      541 atggaaaata cggatatgaa agcaaatatg tacttggcga catcaatatc atgtgttcca
      601 tgcaggagca tttaggtgtt ttattggaac tgaaaggcaa aggctgtcgg caaatggaat
      661 gttatctgct ggcacaggaa cgctcatggt atgacttcat gctggattgt atgacggctg
      721 gtggtgtgat gaaacggctt gatttggcta tcaatgataa agcaggaata ttggatattc
      781 caaagttaaa ggaaaaatac aaggctggcg aatgtatgtc ctacttccgt atgcagaaag
      841 attacagcgg tacagaaaaa tgcggtagcg atttaccaaa gaatacagga gaaaccttat
      901 atctcggttc aacaagtagc gaattatata tgtgtgctta tcagaaaaat tatgagcagt
      961 atgtcaagaa tggcacagaa attgaagata cggagattaa gaaccgtttt gaaatacgca
     1021 tgaagaacga acgagcctat tatgcggttg tagatttact gacctatcgg gacgctgaac
     1081 gcaccgcttt ttctatcatc aatcattatg tccgctttgt tgacagagag gacgacaagc
     1141 caaaaagtca atggataaca aatgatgatt gggcatggtt tgtaggggaa aacagagagc
     1201 cgatacgctt aaccacaaag ccagagcctt acactttaca aaaagcgttg cattggctac
     1261 aaagacaagt cgcaccaacc ataaaaatgg tacaggcatt agacagagaa aatcgtacaa
     1321 cgatactgaa agatatgatt gagcaggcag aactaaaaga caagcataaa catttattac
     1381 aattagagaa atcaaccata gaagaacgta tagataccgc tgttccacaa gagaatgacg
     1441 gtatttttta atgtaattga aaaatttcag atttagtcag caaagagctg ttttcattcc
     1501 ctatgtgaag tgaaagaaga aaaataaatt ttttattaaa tctgcaacaa aatggctact
     1561 tgcgtacaga tatggtgcga gaaaaggaaa tctaaacttt ttttgaaaat aggtcattaa
     1621 atcggggctt gctgtcccta tatgaagtga aagaagaaaa aagttttgaa aaaatgacgg
     1681 aaattcgtga ttagtggaca gtcttctgtg aaaagaggaa aaacatcatc attttgtatt
     1741 caaacaggca ttagcagttg agtgttgatg tgaaaagatg aaaatacttt gttctcaact
     1801 taacaattta aggtttccgt tccctatatg gtgcaaagaa aatatttcat tctattgttg
     1861 gcagtaacgg tatggtttgg gtagttaggg tgtgaaaagg aaaatattct tttttcatca
     1921 tcaacttagc aaaatgacat tttctatccc tatatggtgc atgaaaagaa gttaaaattt
     1981 ttccatttaa acttagcaaa tggacgtttg ctgtacagat agtagtgaaa aaggagaaaa
     2041 tcaaccgttg attgccaaaa tgaaccgttc catttgtact aataatggaa aaagttttgg
     2101 attttggtta cgtttctcct cttttccaac gcgatatata ggaaagacga tttttttctt
     2161 tcaatcgttc tttgacaact gaataaagct attcaatacg tttgacagac agctagccgt
     2221 tgaaacaaat acgccacgac ctttcccctg caagagcgag cgaaaaccta tttgtgttct
     2281 tgtaaaagat ttgtcctctt ttatcgccat gacctgtact gtcagataat gatactcccg
     2341 tacagccaca gcttgagcat taagagcgtc gcacgcaatg ggtacggcta cataagaact
     2401 atgcagaggt ggaactcctg tgggctatga caaaagccgt tgaattgctt agaaagattt
     2461 tacagaaagg gggtatgtgt tattgataat gctgtaaaaa caattcaaaa gaaaaatggc
     2521 aagtgtggca ttggcaacag aggaaagaca aagattgtag taaaagagca tttttccgaa
     2581 aagggcaaaa caatggaaga acttctaact gatgtcatgc tggaaaaagc aaagcagaca
     2641 atcgcataaa atcggtgcag ttgtaagaaa tagattgaat gacaaaaagt acccgtgtta
     2701 tactttactt gcaagcaggt attgtaaaca cgggttagtt ataaaggagg ataactgaca
     2761 atgaaacaac agatttacaa tactgcactt tatcttaggt taagccgaga tgatgaatta
     2821 cagggcgaaa gttccagcat taccacacag agaagtatgt tgcgtttata tgcaaaagaa
     2881 catcatttga atgtcattga tgaatatatt gatgacggct ggtcgggaac aaattttgac
     2941 agaccgagtt ttcaaagaat gattgaggat atagaggcag gaaaaatcaa ctgtgttgta
     3001 acgaaagacc tttcccgtct tggcagaaat tatattatga caggacaata tacagaattg
     3061 tatttcccta gtcataatgt ccgctacata gcgattgatg acggtgtaga cagcgaaaaa
     3121 ggcgaaagtg agattgcacc atttaagaac atcatcaatg aatgggtggc aagagataca
     3181 agccgtaaag tcaaatcagc atttaagaca aagtttgcgg agggggctca ttacggtgct
     3241 tatgctccgt taggatataa gaaacaccct gacatcaaag gaaaactgtt ggttgatgat
     3301 gaaacaaaat ggattattga aaaaatcttt tccctagcct atcaaggtta cggaagtgca
     3361 aaaatcacaa agcagttaag agcagaaaaa gttccgacag cgtcatggct aaattttaca
     3421 agatacggta cttttgcaca tatctttgag ggaaaacccg aaagtaagcg ttatgagtgg
     3481 acgattgctc atgtcaaggc gatattgaaa agtgaggttt atatcggaaa cagtgttcac
     3541 aatatgcagt ctacggtatc gttcaagagc aaaaagaaag tgcgtaagcc cgaaagtgaa
     3601 tggtttcgag tagaaaacac tcacgagccg attattgaca aggaagtgtt ctatcgtgtg
     3661 caggagcaga taaaatcaag acgcagacag acaaaggaaa aggcaacgcc gatttttgca
     3721 gggcttgtca agtgtgcgga ttgtggttgg tctatgagat ttggaacgaa taagacaaat
     3781 aaaacgcctt acagttatta tgcttgcagt tactacgggc agtttggcaa aggtaattgt
     3841 tctatgcact acattcgtta tgatgtgctg tatcaagccg tattggaacg cttgcagtat
     3901 tgggctaagg cagtacagca ggacgaagaa aaggtattga acaagataca gaaagctggc
     3961 aatgcagaga gaatacggga aaagaagaaa aaggcaagta cattgaagaa agccgagaac
     4021 agacaaaatg agattgaccg tttatttgcg aaaatgtatg aagatagagc ctgtgagaag
     4081 ataacagagc gaaattttgt gatgttgtcc agcaagtacc aaaaagaaca gatagaactg
     4141 gaacagcaga taacaagcct aagagaagaa ctaagtaaaa tggaacagga tatgataggt
     4201 gctgaaaagt ggattgagtt aatcaaggaa tattccgtac caaaggaact gacagcacca
     4261 ttattaaatg ccatgataga aaaaatcctc atacatgaag caacaacgaa tgaggataac
     4321 gaaagaatac aggaaattga gatatattac cgatttattg gaagagttga gtaatcaaca
     4381 agagtaatat ttttaactaa gggaaaccgg cggtgtctat acttgggtca gtcgcacatt
     4441 gggaaaacga ttcggttttg ccgcaatctt tttccaatgg tttgagataa cagttggcta
     4501 cttgaccatg ctgtatttct taactggtgc attatcctat gcaacgggta ttggtgctat
     4561 acaaaacaat aaatatctga aattggcaat cctattgatt attttctggg ctattttact
     4621 ctcacagtta aaaggaacca aatacacttc attgattgct cggatcggtt ttgtagctgg
     4681 tatcttgttg ccagcattag tcttgtttgg cttagggatc cattatgtcg cttcaggcgc
     4741 tccactacaa acgatactgt ctatgaaaac attgattcct gatttttcga aattgcctac
     4801 gctggttgtt tttgtttcct ttattttagc atatatgggc gtagaaacat ctgccagtca
     4861 tgcaaatgaa atggaaaacc ctaaaaagga ttatccatta gcaatgtttg tattggttat
     4921 tctggcaatc attttagata cttttggcgg attgaccgtc gctactacag tacctcaaca
     4981 tggtttgtct cttaatacag gggtgattca atcgttagaa ttcctattaa gacacattga
     5041 tccaaatctt gcatggattg cgaaaattct tgcgattctt gtttgtttag gtgtcatcgg
     5101 agaaattgct tcttgggtaa cctctccttc aaaagcactt cacgtagcag cagaagaagg
     5161 attacttcct gaatattttg caaaagaaaa cacacacggt gttcctgctc atttgatgat
     5221 cgcaaatggg atcgttgcaa caatctgggc agccgtcttt acattaagcg gcggggggaa
     5281 taatctttca tttcttgcag cgatgtcatt gactgttgta atctacctga tgttgtactt
     5341 tatgtttttc gcgggctatt tgaagctggt ttttaaagat gacagtcttg aaagagccta
     5401 tcaggttcca ggcggaaaag ttgtaaaagt aatcgttgct tgtttaggtc ttttgacttc
     5461 actttttgct ttttgtatct catttgttcc acctgctagt atcgcagctg gacagcatgg
     5521 gatttatgaa acgattctga ttgtttctta tcttatcgtc ttagttattc catttacgat
     5581 ctacgcatgc cgtcataaat tccagcatgc agaaaaataa aaaatgaaag ctggttattc
     5641 aaatggaagt aaaagaatta gaacaattga ttggaaaaaa tttccactat tatcaaacag
     5701 gacaagtggc ggattacatt ccagcattag ctgaagtgga tcccaaacaa ttaggtatgg
     5761 cgatttatga tttggataca aaacaactga ttgagggagg agacgccgat gtgcgctttg
     5821 ccatcgaaag catgtcaaaa gttcccgtat tgttattagc aatcaaagac aacggaatag
     5881 aaaaagtctt tcaaacaatc aacacggaac caaccggttt tgccttcaat tctatcatga
     5941 atatggaaat caatcatcgc aaacatccaa tgaatccttt tgttaatgca ggagcgattg
     6001 caacaacctc gttgattgcc ggtaaagatg cagatgaaaa atttgagcga atcttgtcat
     6061 ttatgaaaga gatctgtgat gatcctaata tcacattgaa tgaagaaatc tatcattctg
     6121 aatcaagaac aggtgatatc aatcgctctc ttgcttacta tatgaaaggt aatcaaatga
     6181 tcgaaggaga cgtaccggag atactcgatg cttatttcag acaatgctcc ctcaatgtca
     6241 ccgctacagg catagcaaaa ttagctgctg tgctggcaaa taaaggaatt gctccttgga
     6301 atggcaaaca aatcattact gaagaaagtg ctacaatcgt caaatcaatt atgacaactg
     6361 ctggtttgta tgatgaatca ggagagtttt ccgtccatgt tggtgtacct gcaaaaagcg
     6421 gtgtaggcgg cgggttgatg gcagctgtgc caaatcgtta cggcataggt gtcttcagcc
     6481 cggcactaga tccatttggt aacagcgcag ctggtatcca attgttgaaa gatgtagtca
     6541 aagaactaga cgctgacatc tttgaataac cattcttgaa agaggctggg gtaaaagtcc
     6601 aaacggctca aagctaccta caatgaggct gaaattgtga gcttgtttga cttttgtccc
     6661 agtttctttt tttattggtt tttgaaaggg cttttctaaa taaaaaggaa acaaaaatac
     6721 gatttacaga tatgattaaa taaaatcata agaaaaactg gaggcgtgta tcaggaatgc
     6781 tggaaaatta catcgagcga aatatattta gaaaagtgta tctgtgtgaa caattatttg
     6841 aattccaaga aatagacatc gaacaaacag ctatttctct aagggtgact acaccaacga
     6901 tccttcacga tctagaaagt ctagccgagt gtctagaata ttgtataaaa gaacaagtaa
     6961 gagagaagca taagtataaa ctcgtattca aacatggtat tgctctttct gagctcacac
     7021 agtttctgta cggtcaatct tattttttaa agtttttaag ttattatttt aatggtatat
     7081 tcacgagtac agaactggct gatcttgaat ttatttcttt gagtaaagta tatacaatca
     7141 aaaaaatcgt attggatttt tttaaagaaa atgattattt gaaaaataaa gaaatcatta
     7201 tcccagaatt tgactcgcgg aacatcttgc tagctttagt acgttatgtc aattgggaag
     7261 gctatgaaaa taaaaatccg tatgtagaag aagcttgtaa cgagttgatt gattatgtag
     7321 agactcattt ttttaaaaga agatattcgg aagatgaaaa gtcctttatc atacgagaaa
     7381 tagagatcgc aatcggaaga aaggcatttc cccttggact gaaagaagaa gataagaaaa
     7441 gcgcagaaac gaagccgtta tttcaattag tctgtcaagg attggaagag caaaaaggaa
     7501 ttctagactt acaagaagaa gatgtctatt atattttttc tttgttcaac agtagaaatt
     7561 ataccaatga gaacatggag ctgttaagaa aagatttcga agttgtttat aaaaattttg
     7621 ttctcaatga cctatcactg aatgaattga ttttacagat tattagtatc gctgaaatcg
     7681 acgatgcaga aaattttatt ttcaagcaat cctttttaca atttgtccgt acgttgtggg
     7741 cagatggaca agtattttta ccggaaagga tctatcttct atcagaaaaa gaacaacttc
     7801 tgtacggaaa aattgtagaa atattggaag agtggaaaaa gaaaaatcaa atccaactaa
     7861 gatggaatga aaatttcatt cgaaaattcg tcaaaagtct ttctttgatc aacagtgaac
     7921 aagcggggag acaggaaata gaaatttttg ttgtttcaga aagttcagtc aaacaatttt
     7981 tttatcgaac ccaatttcat ttgtatgcgg aagaaggcat cgctgaaata aatcctattt
     8041 tatttcgttc attagaagaa ttgcctgatg aatgtctatg tgcgaaaaaa agagtggttt
     8101 tgtgcgatgc tgctagctat caaaatggat tagaaactga aaagacaaag atctatccaa
     8161 tctcattaaa aggtgcaaac atccatttgt atcatattgc tcaggaactt cacctattaa
     8221 aaaaacatat ttcttgatga gaccttaatt aggagacctt ctacaaagct ttttaattgt
     8281 ctgtagaagg tttttatttg agtcctgatt cgtgcgaaga tctacttata taacaagctt
     8341 tctctgaaat ttttttaaaa tgctattgac ttagagtcaa ctctaagtag tagaatagat
     8401 aaagtgtaac aaatctattt tcattaaaag aagatagtac ggaggagaga atgtattatg
     8461 agtacagtat tacatgtatt ggatgcaatc aatagccccg cagatgtcaa aaaattatct
     8521 gttgaggaaa tgaaacagtt ggcagaagag atgcgccaaa aaatcttgca aaaggacagc
     8581 gatgtaggtg ggcacgttgg tccgaatcta ggtgtagtag aattaacgat tgcgtttcat
     8641 tatgtatttg attcaccaaa ggataaaatc gtttgggatg tttcccatca gtcttatggt
     8701 cataagcttt taactggtcg aaaaaatggt tttgaaaaag gacattaccg tgaagtgagc
     8761 ggatattcca accaacatga aagtaaacat gactatttta cagtggggca cacatctaca
     8821 tctatcagct tagcaacagg tttagctaaa gcgagagatc tgaagaaaga atcaggaaat
     8881 gtggtagcat ttatcggtga cggctcccta agtggtggct tagcttttga aggattgaac
     8941 aatggtggtg ttttacaatc caatctaatc gtattagtaa acgataatga gatgtctatt
     9001 gatgagaatc atggcagttt atataaaaac ttagctgagc ttcgtcaaac caacggtaaa
     9061 agcagcaata acctatttaa agcaatggga tttgattatc gttacgtgga taatggaaac
     9121 gatctggaaa cggtgatccg tttatttgaa gaagtaaaag atattgatca tccgattgta
     9181 cttcacgtcc atacggaaaa aggtcgcggt tatcagccgg caatcgataa taaaatgaaa
     9241 tatcattggc atgtaccatt tgatctgtcc accggggagg caaagcaagt aacttctgga
     9301 gaaacattta atatgatcat catggattat ttggataaga aaatgcaaac aagtacagct
     9361 cctattgccg cagtcaatgc agcgatacca ggcgcctttg gactgaaaac attccaagaa
     9421 aaacatccag atcattattt tgacgtgggg atcgctgaac agcactctat cactttcgct
     9481 tctgctttgg cttctcaggg agtacgtcca gtcgtcttcc aatcaagtac tttcttgcaa
     9541 cgggcatatg atcaattatc acatgattta gcgatcaacg agaatccagt gattatttta
     9601 gtcggtggcg gaacgatctc agctagtgac cgaacacacc aaggaacatt tgacattcct
     9661 tacttatcaa gtatcccgaa catcaaatat cttgctccag caacaaaaga ggatatgatc
     9721 tctatgctag attgggcgtt cgaacaaaca gcgcagcctg tagcaatccg aattcctaca
     9781 catggtgtag aacatggtac agctatcgca aatgattata gtattccagc ctatcaaaca
     9841 gtaaataatg gaggaaaagt agcaatttta gctttaggcg gttttcttga attaggaaaa
     9901 gaaacagtaa aagcttttag aaaaaaagga atcgaagcaa cgttgatcaa tccaggaacg
     9961 atcacagaaa atgacgtaga aacattagat aaattaaaag aaacacacga attagtcatc
    10021 acattagaag atggtagttt gtcaggagga tttggcgaaa atatcagtcg ttattatggt
    10081 gattcttcaa tgaacgtatt aaattttggt gcagagaaag aattcacgga tagcgttcct
    10141 gtagggcagc tttatgaacg ttatcattta acaccaaaac aaatcgttga agatagtctg
    10201 cgtgtcttga atattcaata attcattatg ctcaccatcc agataattgt ttatactagt
    10261 atctggatgg ttttttcatt ataaaaagca aaggggtgga tgttatgtat cagcaagtag
    10321 aagaatatgt caaaaagttc caagaaaaat atcctagtta tcaatcagaa aaattaggtt
    10381 tcttttcatt tggggataca gaaaaaatgg cagacgagtt gagcgaacta gttgtaaaaa
    10441 agataaagac tggtacatca agtggttacg atctgtataa acaagagaat gagcctttac
    10501 caaaagttgg tcaattagac gtggtcctga atggaaaaaa tgaaccagtt tgtatcatca
    10561 aaaatataaa tgtgaccatc ttgcctttta gtgaagtcac gaaagagcat gcttggaaag
    10621 aaggagaagg ggatcggaca ttagcttatt ggcggaaagt ccatgctgag ttttttaaac
    10681 atgcttataa agaagcgttg aacatagaat ttacagaaga gaagctggtc gtatacgaag
    10741 aatttgaagt aattttcttt tagtaagaaa ggtctgctga aagaaatagc tcattattgt
    10801 ctcctgaata gaaaagggtt acatttttat atgaagctgt atttttatat aacattactg
    10861 gaggagatat tgtggataca ctggaacaaa tcaaaggcgg agtcgtcgtt tcttgtcaag
    10921 ctttggaaaa cgagccgcta cacagttctt ttattatggg gagaatggct ttggctgcaa
    10981 aagaaggcgg agcagttggt attcgagcaa atacgacaga agatatcaat gaaatcaagc
    11041 gaatcattga tttaccggta atagggatta tcaaaagaga ttacgatggg tcagaagtgt
    11101 ttattactgc gacagaaaaa gaagtggaag aacttttgga gacgcaagca gaaatcattg
    11161 cactggatgc aacttctcgt aaacgtccga cagaaaaaac aactgctgaa cttgtccaaa
    11221 tgattcacga acacggtcgg ttagctatgg cagatatttc gacttttgag gaagcgcttc
    11281 aagcgcaaga agatggtttt gatcttttgt ctacgacttt agcaggctat acagaatatt
    11341 cacgaaagac gcagacacct gattttgatt tattgaatca aatcatagaa caagtcgata
    11401 tcccagtaat tatggaagga catactgact ctcctgaaca agtagagaaa gcatatgaat
    11461 taggtgcttt ttcagtcgta gttggatcta ttatcacccg tccgcaattg atcactaaaa
    11521 gatatgtcga agccgcaagt aaagcaaata actaaaaaac acgcacggca cagattcttg
    11581 acaaaaaaga aaaattgata gatagtttaa agcagattct aagaagatga aaaaagcatt
    11641 acttttcatt ttgtcttcaa gatctgcttt ttaacgaatt ttatagaaag aaggcgaaac
    11701 catgtttgaa cggagtcctt cagaattgac agaacgtgaa aattacaagt tgctgattgg
    11761 ttcagtcatc cctagaccag tagcagtagt aacgactaaa tcagcaaaag atatagtgaa
    11821 tatcgcaccc ttcagttact tcaatatcgt cagttcgaat cgacccatct tatccttggc
    11881 gatccagaga aaacaagatg cagtaaaaga cacagcaaag aatattcttg agacaagaga
    11941 agctgttatc catatccttg atgaggacaa cgtagaagaa gtaaataaaa cagcagccaa
    12001 tctgcctaat gaggaaagcg aactgtacct gactgacttg actttaactg attcagtaat
    12061 catttcagta ccagcattga cagaagcaaa agttcgtttt gaaacatcct tatatgaaca
    12121 tgtcgagata cggaataaaa ataaagtaac agctgattta tttttgctag aagtacagaa
    12181 atatcattta aatgaaacag tctatgatga taagacagga aggatcgatc caagaaaatt
    12241 gaatgctgta agccgtttgg caggaaatga ttatgcagca ataggagaaa ttttcacgat
    12301 tgcacgtccc gaataaaaag gagcactagt tatgttaaaa ataagctata aaccatcgac
    12361 agattcaaaa gaaatgaaaa aagaatatga aacagtgaat gattttctgc aagggcagta
    12421 cttagaagtt ccgccattgc aagaccattt tgtcgttact actgttactt tagatggtaa
    12481 ggaaatagaa atgccagatc aaacgattag cggattgttt aattacttta acaaataaat
    12541 atttattccg aaaagtgaaa aaacatataa aaaaacacat aaaactaaaa aattatcaaa
    12601 gaatcctggt gcaactgaaa gaatttgcaa cgggattctt tcaacttatt tgttattttt
    12661 ttctaaaaaa tattaaagat tgttaaattt cactatttca tttcaaattc cattgcctaa
    12721 tcattaggaa aagtctatca tgaactcgta aatagaatat agtaataacc ttgttaggtg
    12781 aggctcctat acaaacatag gctgttgccc agaaacgtcg aaagtcgcca atgggtaaaa
    12841 cagaaactgt tggattaagg ctttttccaa tagctaagaa tgttttcttt acgttgtata
    12901 gtgctaaaac tcggacgatg agatgatgct aggtcagaat tcttgttcga aaaggtttct
    12961 gaccttttct ttatattttt gtgactgact tatttgatga gacaaactcg ctcctcacct
    13021 gacaagtgga ttgctgtgtg aggaggagat gcggtgaaaa aagatcgatt ggtggatttt
    13081 gggtccttat ttgactttgt ccatgatcgg tcttttagaa gtatacagtg ccagttctta
    13141 tcgtttattg caagccgatg aaaatacaaa aagtctatta ttgcgtcaac taattttcat
    13201 atttttgagt tggagcgtga tcttcttagc tcgttcagtc aaactacact atttacttca
    13261 ccctaaaata gcaggatacg gtttagcctt atcgattttc tttttagtat tagtaagaat
    13321 agggatattc ggtgtcactg tcaacggcgc acaacgttgg atctctctgt ttggcattca
    13381 attccagcct tctgaactgg caaatctttt tttgattttt tatttaagct ggttttttcg
    13441 tgacggaaat agtagcccaa aagatctaaa aaaaccattc ctgattacag taggtataac
    13501 ttttctgatt ttatttcagc caaagattgc tggagcattg atgatccttt cgattgcgtg
    13561 ggtcatattt tgggcagcgg cggttccatt taaaaaaggg atctatctaa tcgttacttt
    13621 ttctgcattg ctgattggag cagcaggcgg ggtattatat ttaggaaata aaggttggct
    13681 tccacagatg tttaatcatg cttatgaaag gatcgcgact ttaagagatt cttttatcga
    13741 tagtcatggt gcgggctatc aaatgaccca ttcgttttat gcactatata atggtggcat
    13801 atttgggcgg ggattaggaa atagtatcac aaaaaaaggg tatcttccag agacagaaac
    13861 agattttatt ttttcgatta ttacagaaga gcttgggcta atcggtgcat tgtgtgtgct
    13921 tttcttattg ttctcattat gcatgagaat cttttgttta agcagtcgct gtaaaaatca
    13981 gcaagctgga ttgtttcttt taggattcgg aactttgcta ttcgttcaga cgataatgaa
    14041 cgtgggaagt atcgcggggc tgatgccaat gactggtgtg ccattgccat ttgttagcta
    14101 cggaggaaca agttatctga tcctttcttt aggaatcgga atcacgttga atatttcttc
    14161 aaagatacag gccgaagagt tggcgctcta tcgacctgaa aaacaataaa gagaaactga
    14221 gaaactctca gtttgaatta tcataaagta caatctttta tttttcaagc gagaggttct
    14281 tttagaaaga ggaattcgca atgaaagtat ctcaaaaaat catattatct attttgttac
    14341 tgcttacatt agtagttggc tatttttcga ttgagtttat ccatggattt tcgtctgcaa
    14401 aacagagttc aactgtgaaa aaggtagagc cgaaaagtat ccctaccaca ctaaatgtgg
    14461 ctttgattgg ttcagatgct cgttcgaaag acgaaaacgg tcgctcggat tcacttctgg
    14521 ttgcacaata caaccagaaa acacaacaag caaaactgat ctctatcatg agagattcat
    14581 atgtcgatat tccaggttac ggaatgaata agataaatgc agcttactct tatgggggag
    14641 ttgatttatt aaatcaaaca ttaaaggaaa atttcaaatt tgaagctccc tattatgcaa
    14701 gtatcacatt tcaagatttt atcgattgcg ttaatgaact gtttcctggt ggagtcaaga
    14761 tcgatgcaga aaaatctcta gatttagatg gcgtatatat aaacaaagga gagcaagtga
    14821 tggatggtaa tactttactc cagtatgctc gatttcggga agacaaagaa ggagacttcg
    14881 ggaggatcag aaggcagcag caagtgatca aagctatctc tcagcagctg aaagacgtaa
    14941 cttcaatatt caagctaccc aaagcggttg ggaaattact tggtagtatc caaacgaacc
    15001 ttccagaaag tgtgcttctg gattgtggta tggatttcct caaagacata tgttagaata
    15061 aacaggtata aatagtgaaa taaaggaatg acaagcaaga gaaggaggaa aaaatgaaaa
    15121 gaagtgacaa gcacggcaaa aatcgaacag gcgcttatat tgccggcgca gtgatcttaa
    15181 tagcagctgc gggtggcggt tatttttact accagcacta tcaagaaacc caagcagtag
    15241 aagctggaga aaagacagtt gagcaatttg tccaagcttt gaacaaggga gattataaca
    15301 aagctgcaga aatgacatca aaaaaggcgg caaataaaag tgcattatct gaaaaagaga
    15361 tcttagataa ataccagaat atatacggtg ctgctgatgt caaaggactt cagatatcga
    15421 atctaaaagt agataaaaaa gacgattcta cttacagttt ttcatataaa gcaaagatga
    15481 atacctcatt aggtgaattg aaagatcttt cttataaagg aacattagac agaaatgatg
    15541 gtcaaaccac gatcaactgg caacccaact tggtttttcc agaaatggaa ggaaatgaca
    15601 aagtaagcct gaccacacaa gaagcagcaa gagggaatat tatagatcga aatggtgaac
    15661 cattagcaac aacaggcaaa ctaaaacaat taggagtcgt tccaagtaaa cttggagatg
    15721 gaggcgaaaa aacagccaat atcaaagcga ttgcttcctc cttcgactta acagaagatg
    15781 ctatcaatca ggcgatttca caaagctggg tacaacccga ttactttgtc ccattgaaaa
    15841 tcattgatgg agcaacgcca gaacttccag ctggagctac cattcaagaa gtagacggca
    15901 gatattatcc tttgggtgaa gcagctgctc agctgattgg ttacgtggga gatatcacag
    15961 cagaagatat tgataagaat ccagaattaa gcagtaatgg aaaaatcggt cgctcaggtt
    16021 tggagatggc ttttgataag gatcttcgtg ggacaacagg tgggaaatta agcattacag
    16081 atgcagacgg tgtagagaaa aaagttctga tcgaacatga agttcaaaat ggcaaagata
    16141 tcaaattgac aatcgatgcg aaggcacaaa aaacagcttt tgacagtcta ggaggaaaag
    16201 ctggatcaac tgttgcgaca acgccaaaaa ccggtgatct tcttgcgctt gctagctctc
    16261 caagctatga tccaaacaaa atgacaaacg ggatctcaca agaagattac aaagcttatg
    16321 aagaaaatcc tgaacatcca ttcatcagcc gatttgcgac aggttatgct cctggatcta
    16381 cgtttaaaat gattacagca gcaatcggtc tcgacaacgg cactatcgat ccaaatgaag
    16441 tgttgacgat caacgggctt aaatggcaaa aagacagttc ttggggatct tatcaagtaa
    16501 cgcgtgtcag tagtgatgta tcacaagtag acttaaaaac tgctttgatc tattccgata
    16561 atatatatgc ggcacaagaa acgttgaaaa tgggtgagaa aaaatttcgt acaggcttag
    16621 ataaattcat ttttggtgaa gaccttgatt tgccaattag tatgaatcca gcacaaattt
    16681 ctaatgaaga tagctttaac tcagatatct tgctagctga tactggatat ggacagggcg
    16741 aacttctaat tactcctatc cagcaagcag caatgtattc tgtttttacc aacaatggca
    16801 cacttgtcta tcctaaattg attgcagata aagagacaaa agataagaag aatgtcatca
    16861 gcgaaacagc agtacaaacg atcgtgccag atctgagaga agttgtgcaa gatgtaaatg
    16921 gtacagcaca ttctctttct gctttaggga ttccgttggc agcgaaaact ggtacagcgg
    16981 aaatcaaaga aaaacaggat gtaaaggggc aagagaacag tttcttgttt gctttcaatc
    17041 ttgataacca aggttatatg atggtcagca tgttggaaaa taaagaagat gatgattcag
    17101 caaccaaacg agcatcggaa ctattgcaat acctcaacca aaattatcaa taaaaaattg
    17161 ctttttaagt acagtaaaag gactgtggcg ttatcgtcac agtccttttt tcaaataaac
    17221 ggttttcacg atgtctcttt cacaacttct ttttgattta ctcacacttc ataaactttt
    17281 tttgtaaaat atttgagaac aagtggagaa ataagtgtac ttaataaaat cacgataact
    17341 aaaggtgaat agtactgtgg ttcgatcaat tgactttgct gtccaatttg taaaatgatc
    17401 aaagccattt ctccacgcga aatcatacca gcaccgacca tcaatgaact atgttgagaa
    17461 aaaccggcaa tctgagcacc aaaataacct ccaagcaatt tggtcaaaat cgctacaagc
    17521 gtcaatatag aaataaagag tagttgttca ctaaagtcag aaaaatcaac ttctaatcct
    17581 acactgacaa aaaatactgg tataaatact gcatatccta aagcctctac attgtggtat
    17641 acttcttctt taacctttgt ctgactgaca gctatcccag caaaaaaagc accaatgaca
    17701 gagctaagcc caacaagatc cgctacgtaa gacattccta aacaaataac tagcgatacg
    17761 atgataatag aagaatttgc gtacactttt tctgcaaatg aaagtaggaa aggcgcaatc
    17821 catttgacta ataagaaaat aaaaacaaaa taaattagct gttcaatcaa aacaagcggt
    17881 aaagaagcat tgctagaagc ttcccccgtt agaaaagata ggctgaaact tagaactaaa
    17941 acgactaaaa tgtcatctac cacagaagca cccaaaattg ttgatccttc ttttgtattc
    18001 actacgttta gttcttttaa tacttctact gaaatactga cagaagttgc cgcaagaata
    18061 atcccaaaga aaatcgcttc atttcccgaa acttggaatg ctttgcctgt caaccagcca
    18121 aaaacaaccg ggaagatgat cccaagcaaa gcaacgaaca taccaggtcg gaaatatttt
    18181 ttcaaaagag ataaatcact ttccagacca gctaaaaaca ttaataagat cacaccaatc
    18241 tccgaaaagt catggactag aatatcaggt ttgacccaat tcaatccagc ttggcctagc
    18301 aaaacaccaa caagtaattg tccaatcact gctgggatac ctaatctccg cgagatatgt
    18361 gagccaatcg ttgttgaaat caatatcagg cataaaatac caataaattc cattctcatc
    18421 attcctttgt ataaaatata gcccgaactt agcataacat acattattga aaaaatagga
    18481 aaatatactc acaaaaaaac caacaatcca aaagattttt ttggattgtt ggtttttata
    18541 cggtctattt taataactaa aaatgattaa cgtatagtca tttttcttat tctgatgaaa
    18601 ttgataatct cctggatgcc catgaaaatc aaaataaagc cgaatatttg gaatagaagc
    18661 atcaaacttt tgaatggatt gaacaataag acgaatccgc caatcaacaa cagaatacta
    18721 ctataaacac tccaactttt agcttttgta ttcatgctga agaacaactg gaacaagctg
    18781 ttgatgataa cagctaatcc aagaagaatc ggcaggatag aaacgattgc aggtgcaaaa
    18841 gcatagacga tcagagctaa gatcaggaaa aaaagaccac tgaacagacc gatactccaa
    18901 gaacctgttt tccttttaaa acggtaagcc tcaaaaagat tcaacaaccc aagcaaaaca
    18961 agataggcgg tgatcagata accgataaaa tgaaaaacag cagaagggtt tagcacaatc
    19021 gcaatcccag aaataatata aacagcagct cttaataagg cgtatttttg aatattttgt
    19081 ttaatcgtct caaacatata agaaaacctc ctttgactta ttttaacgtg aactagtcat
    19141 tttaccaaat taaatgttac aaaatgagcg aaggagaaga atatctctgg aaaaatcaac
    19201 ttctgaggat cttttccatt tttttgcctt ttgctagctc atcgatcatt ttatctaaat
    19261 aacgaatttc tttcatcaag ttatcctcga tgtcttctac tcgtacacca caaacaacac
    19321 ctgtaatcaa ggaacgtgaa ggattgggga caggggcttc cgcaaaaaat tgttcgaaag
    19381 tcacttgttt ttgtagttga tattctagtt ctgtttggga ataacccgtc agccaacaaa
    19441 tgatttcatc tacttcctct tttatacgat cttttctctc cgcttttgct acatacatag
    19501 gataaacgct tgcaaaactt gtcgtaaaaa tacgattttg cgccataatc agtcaccttt
    19561 ctttttttca aattatttac tacttatagt atataagaaa aagagaagaa aaagcgatta
    19621 ttcaaaaaaa caaaaaggat tgtgacaaaa ttcttgtcac catccttttt tccgctctct
    19681 gactttttac aatcttcata gctcaagtgc gcatcagata atcgaatgct cctaaagctg
    19741 cagtagctcc tgaacccatt gaaacaatga tttgtttgta tggactatct gtacaatcac
    19801 cagctgcgaa aacgccgggg atattcgttg cgccattttt ctcggtcact atttcatttc
    19861 ttggattcat ttcgatcgtt ccatctagcc aatccgtatt agggagtaag ccgactagaa
    19921 tgaatactcc tgaaacagct agtgtatgca tctccatcgt acggcgatcg atataggaga
    19981 gagattctac ctgattcgta ccgctgattt ctttcgtcgc tgcatgtttg ataacagtga
    20041 cattcgcaag agagactagt ttatcctgta agatttgatc tgcttttaat tctggtaaga
    20101 attctagaac atatacatgt tttgctaacc cagccaaatc gattgctgct tcaacaccag
    20161 aattaccacc accgataaca gcaatctctt ttcctttaaa taaagggccg tcacagtgtg
    20221 ggcaataagc aattccttta tttttaaact ctttttcgcc tggtacattg atagaacgcc
    20281 agtgcgcacc tgtcgcgatg atggcggttt ttgctttaag tgatataccg ttagctaagc
    20341 caatattaat aaaatgttgc tctttattta aggaaacggc ctgttgattc atcataatgt
    20401 cgatagggta actacgcaca tgactttcta cttgctgcat caattttgga ccttctgtgt
    20461 aagaggtacc aatcatattt tcaatcccta gtgtttcaac gacttgtccg ccgaaagaat
    20521 cagcgacaag tcctgtacgg attcctttac gtgctgcata gatagctgca ctactagctg
    20581 ctggtccacc gccaatcact aatacatcat aaggttcttt ttcaaacaac tcttcttcaa
    20641 tcaaagggcc agtgattttt tcaacaattt gttcgatcgt catgcgtccg ctactaaatt
    20701 cttctccatt taaaaacaca gttggcactg ccatgatttt tttatcatcg atttcttttt
    20761 ggaacatccc accttcaatc atcgtatgag taatatttgg atttaataca gctaatatat
    20821 tcaatgcctg tacaacgtcg gggcaattat gacaagtcaa gctaacataa ctgtcaaaat
    20881 gcaatgtttg tgttattttt ttgattttaa gactcaaaga ttcactgatt ttcggtgccc
    20941 gtccactaat ttgtaacata gccagtaaaa aagaggaaaa ttcatgaccg agggggatac
    21001 cagcaaaaac gattccactt tctttgccaa ctggattgat agaaaaacta ggtgtgcgca
    21061 tcgaatctct tttttcccaa gagattttag gagacatttc tgctatttcc ttcgtaaatt
    21121 cagctagttt ttgactattt tcactattat ccaaactaac agaaaaaaca ataggagatt
    21181 caatcagtgc taaatattgt tcgagatttt gtttagtttc tttgtctaac atatccacca
    21241 cctaaatctt tccaacaaga tcaaaacttg gtttcaatgt ttcgccactt tctttccatt
    21301 ttgccggaca aacttcacct gggtgggtac gtacatattg agcagcgcga atcttatcaa
    21361 tcagtgcact agcgtcacga ccgattccat ctgcattgat ttccatagct tgaacgattc
    21421 cgtctggatc aataataaat gttcctcgct gagctaatcc ttgctcttca tccaaaacat
    21481 caaaaatacg agaaatctga tgagacggat caccgatcat cacgtattcg attttaccga
    21541 tagcatctga tgtatcatgc catgctttgt gagtaaagtg ggtatcggta gagcaagaaa
    21601 agacttcaac acctaaagat ttcaatgtac tgtattgttc ttgtaagtct tctaattcag
    21661 taggacaaac aaaagtaaaa tcagctggat agaagcaaag aatactccag ttccccataa
    21721 gatctttttc actgacttct aaaaattctc cttgatgata agcatgtgca ttaaattctt
    21781 cgattttttt cccaatcaat gacatagtaa aacctccaat aataattatt tatttataat
    21841 tattgtaatt tagttggagt tgcaaagtca atggatattt tgttatttaa taaagattac
    21901 tcaaaaacga aggttaatta taaaaataga agaggtcgca agaaaatgct actgctggaa
    21961 atactcggga taacgttgag taacagtttc ctgttctttc agcatcatgt gtaagtgcaa
    22021 tcccgtttga aatcgagctt cttctggttt tttatcaact aaagccttga gtaaatcata
    22081 atgttgttcc atgatcgttt cccatggaag cccctgaatg gtcactcgta accagcggaa
    22141 acgttctaaa tgggtattat ggtcatctaa ccagttccaa acttcttttc ttcctgcaat
    22201 ttcgaaacaa gcttcatgaa ataaattatc tgcacggaaa aaagcgcgtt cgtcatttat
    22261 tttgactgct ttttcttgtt cttctaaaat cgtttctagc actattcgtg tttgtgtgtc
    22321 caatttggaa caacattcaa tcatgatttg ctcttccaac tgttctcgga caaagcgagc
    22381 attttctgca gaaacaagat taattttgga aacatacgta ccactttgag gtatcgtata
    22441 cacgagttct tgctgacgta gttgaatcaa tgcttcgcga atgggagtcc ggccgatagc
    22501 aagatgttcc tccagtgcct tttcagatat tttccttcca ggttctaagt cagcatagat
    22561 aatttgttta cgaatcgctt gataagcttg tgattgcaag ctgcttttca tctttattcc
    22621 tccaaaatca tttctatgaa cgtagtataa cagaagaggt ctgaaaaaca atctggtatg
    22681 tcacattaac tagtaaattt gtataaatag taaaattttg gttgacatag cgatttttat
    22741 tgcataaaat tcacttgaat acaaaaacta atatgttagt ttaggagggg aaaaatgatt
    22801 gatttaaaca actggaggaa ctttatccct gaattatctc aaaaagaagt agaaatacct
    22861 cattttgacc gtgcatcatt aagagaaaat ggacaaaaaa atcctgtctg gatccatttc
    22921 ggtggcggaa atctttatcg aggatttcat gcagaaatcg ctcaacgttt agcggatcta
    22981 ggcgaattgt ccactggtgt cattgtttgt gaaacattcg atgaagaaat aattgaaagg
    23041 gcttaccaag attttgatga tttgattctt gaagtggtca tgccaagcag tggagagttc
    23101 gtcaaacgta tattagctgc gacagctgac agtctgtatt gtcatccaga ttgttctgaa
    23161 cactttgata agatgattcg acactttgaa aatcctagtt tacaattagt tacttttgct
    23221 attactgaaa aaggttatcg attgaaagat acaaataata aatatatagg accgattgca
    23281 gtcgatataa aaaatggtcc aaagaagcca tcacatacaa tgagtattct tgctgtgcta
    23341 ctttataaac gttttttatc tggagcttgg ccgattgcac ttgtctctac agataatttt
    23401 tcacaaaacg gtagtcaatt acgtacttct ttgctaacga tcgcaaaaga atggcaaaag
    23461 gaaggttatg tacaaaatac atttatccaa tacttatcga atgaagaaat tgttgcgttt
    23521 ccatggacga tgattgatcg tatcaccccg aatccttcct tgtcagttag caaaatgttg
    23581 gcaaaagagg gcttttcaaa tatgtcgatt ttccaaaccg caaaaggaaa taatattgct
    23641 ccatttgtca atacagagga catccattat ttaatcatgg aagatcattt tcccaatgga
    23701 cgtccgaaat tcgaaaaagc tggggtattc ttgactgatc gtgcaacggt agataaagca
    23761 gatacgatga aggtgacgac ttgccttaat cctttgcata cgtctttagc tattatgggt
    23821 tgtttactgg ggtataggag catagctgag gagatgaaag atccagattt atcgctgcta
    23881 gtttctgaaa tcgggtacaa tgaaggcctc ccagttgtgg agtctccagg tatcattgat
    23941 ccaaagatct ttctggaaga agtaattact gtgcgctttt ctaatccaaa tattcctaat
    24001 atgcctcagc gaatcgccac ggatacctct caaaaggtgg cgattcgtta tggtgagacg
    24061 attaaaaaat atatggaaat agaagttaaa gacccgcaga cacttgtatt cataccattg
    24121 actctcgctg cttggcttcg ataccttatt ggcattgatg atcaaggaaa accattcatc
    24181 ccgagtccag acccactatt gacagacctt cagcataagc tttccgatat tcaactgggt
    24241 acgcaagata catcacatat tcatgagaaa atggctccta ttttgtcaaa taaagaaatt
    24301 tttggtgtag atctttacca agcagagctt ggcagaaaaa tagaagaaat gttcatcaag
    24361 atggtagcag gaccaaatgc cgtacgaaaa acattacagg attacttaca agaacatgga
    24421 ggaaatttat catggaaatg acttttagat ggtacggatc acaggaagaa aagattacct
    24481 tagatgaaat cagacagatt cctgcggtca aagggattgt aggcacattg atggatatac
    24541 cagtaggaga ggtatggcct agggagagga tcaaagaact aaaagaagaa attgagtctc
    24601 gtgggttaac actaaaagta attgaaagcg tcaatgtgca tgatgccatt aaaattggat
    24661 taccttcccg tgagcagtat atcgaaaact ataagcagac aatccgaaac ttggcagaat
    24721 atggaataga agtcatctgc tataatttta tgcctgtatt tgactgggtg aaatctgacc
    24781 ttgactaccg cttagaagac ggctcatcca cgttagcttt tatatctgat gatattccag
    24841 atgatccaag agaaatcgtc gcgcgcatcg aacattccag caatgaattt ggattgccgg
    24901 gatgggaacc tgagcgctta gctcctatca aatccttgct tgaagcctat gcatcagtag
    24961 acgaagaaaa acttcgagaa aattttgcct attttctcca atcaatcatc ccaacatgtg
    25021 aagaggtagg ggtcaaaatg gctgtacatc cagatgatcc gccatactcg atttttggat
    25081 tagctcgaat cgtaaagaat cgagaagatt tagattggtt gtgtcgcata gtagacagcc
    25141 cttataacgg aatcactctt tgtacaggga gtattgcaga agatccagaa aatgatgtat
    25201 atgggatttt agcagaattt tgccaaagag atcgaatccc atttgcacat gttcgaaata
    25261 ttaaattttt agctaatcga gatttctatg aggcaccaca taaatccgaa tacggttcat
    25321 tagacatgta ccgcatacta aaaacaatgt atgacaacgg atttaacgga tacatccgtc
    25381 ctgatcatgg aagaatgatc tggaatgaga caggaagacc aggatacggc ttatatgatc
    25441 gagcattagg tgctgtttat ctaaatggat tatgggaagc aatcgaaaaa ggaaacaaaa
    25501 gtaaagataa ttagtgaaaa aaactgtaat tttattatgt aaataagaag gatgttcaaa
    25561 ttcttgatac ataaatccgg aggttgttaa taagcattcg gatttatgta tcttatttgg
    25621 tctaggaagt aacttgattt tcttttttcg attgatccat gagtgcttct tcttttaatt
    25681 caaagatata ttctgagatc ctcataatca cttttttcca gtcttctggt gtgatgattc
    25741 cttttaaaat atagattttt ttgatatgag aaggcaattg tttcaaaggg cagtcgctga
    25801 taacgatgtt gcagttctcc ataaaatcat tttgtatttt gatcgattca tttgaaaaaa
    25861 tttgttctat cttaacgatc agatctttac tgatataaaa atcacgcgta tagttcacac
    25921 caatcacaat tcgcggctgt tttttgtagc gatcatacaa atgtactagg tcttcaacca
    25981 tccattgcac attttccttt tctaaaataa ctggtaacaa gtgttgattt tgttctctga
    26041 aatccatata aaattgttca atggcggttt ggacttcttt caatacgcta tgttcttgat
    26101 aaagcatgaa agtaggaagg ggcgtatttg gttgattgaa gttaagaaat ccattataaa
    26161 gtttatttcg tgcgaatgcc aatgagtaaa gaatcttttc tttttcaggt ataaacaaat
    26221 caaatacagt acaaagggac tccaccattt ctcttgaata aagaacatga ggaacgtttg
    26281 ctttttttaa aagtttgtat tgctccaagc ttgtttcttc cgattcgatt ttcgtgatag
    26341 aaagtcgagc taaaatattc actaagatgc gttgttcgcg acaaattggc agattaggtc
    26401 gcaaaatatc tacagagaga tcaataaaaa agtcaatata ttcatactct gtgaattctt
    26461 tttgtacgtc tttcacagaa gttgcaggaa aattctcttt acatattttt aatagaaaat
    26521 ataatttatc tatcataccg ctatttagtc ggtcaagtac ttctttttta aaaaaagtat
    26581 tcatcataaa agccactact tgcggatctt catcataaaa ttctgtagca gtacttgaaa
    26641 agatgttcca ataaatatct aatgctgcat attgaatttg tacctctttt ccagaaaaag
    26701 actttctgcc attattagaa aaggagatag acaaaccgta ctatgctaaa aatgcattaa
    26761 tctttttcat tttcgtatac aaataagagg cactatagtt tgtttgctga ctgaaactga
    26821 taatcgaatt tgtctgacag ctgaacaaag aagtcaagat ctgataactg actgattcgt
    26881 tgcagtatct tccaaataga cgataatagc agtaagccgg atcaattcct tcaaaattca
    26941 actttaaaaa aggtttttgc ttatcaatat gcagttctgt tagattgaga cgctcaaagt
    27001 cttgttctaa ttctttgatg tatagtaaaa aatttgattc agacatatgg aaatgatctg
    27061 ctaaatattg tgtagtaata aagaaacgat gttcagatag gaaaagaaaa atatctaatt
    27121 ttgtattgct ttttttcttc aagataaacg ttttaatcgc ttcttgagtt tgcatgaaag
    27181 aggctccttt ttacttaaat tgttaaaact tgaaaatatt actgtttttt tcataaattt
    27241 agacaaaaaa acagtaaaca tataggtaga atctctacta tcttatttct tgcatacaaa
    27301 aaaatcaagg agtgagagag ttatgagata ttcaaccatc ttaatatcaa catttgcagc
    27361 cttaagctta tcgcttacta taaatcagac agtccacaca gaggagacag aaacagccaa
    27421 atggacagaa accaagtggg ccaacgtcaa tcgaattacc tttcaggatg aattttcatc
    27481 cttcaattca ggagtcgcaa aattaagaaa aggacaaaca gcgaccatca aagcaaaaat
    27541 tgactattcg ggagacttag cacctatact acaatcagct gttacatttg agaatgttga
    27601 tcccactttg tcgattggct atgacgagaa cactttgact atccaacaca agcaagcgat
    27661 atttaccttc accgttacat taaatcagga cttgttaaaa ccagcgcttt ttactgtcaa
    27721 ggtatcagat ggactaccga acgatcatca tttaacgccg tatagtcagc ggcagacaat
    27781 tgagcaagat tcagccatcg actcaggagg agatcttgtt gaagaaccaa cagataaacc
    27841 agaaaatgaa aataagccag aagtaccgcc tacagaaaat ccagacggag aacagaaacc
    27901 ggaaatagaa cctggagaag aacccgatac agaaactcaa ccagagccag acaataaatc
    27961 aaaacctgaa ataacccctg gagaaaaacc agatgtaact ccagaaccag atacggattc
    28021 tggaaaccaa acagtaccgg aaacaaatcc agacacagat aatgaaactg aaaatccaga
    28081 aaaaccagag gtagatccag aagaaaaacc agatgtgact ccagaaccag atacggacgc
    28141 aagagaccaa ggaataccag aaaaaataaa caaaaaaaca attcaagagg atggaaaaaa
    28201 agagagtaaa aaatcaaatc tagcaattct aaaaataaat gaagagcagc tgaataaaaa
    28261 atcacgaata tttgatagcg cccaatcagc tgaaacctta aaaagtagca aggatacaac
    28321 ctttgctgtc ctgaaacgaa aaataaacag ctaccaaaat ccggagagtc acaaaacaaa
    28381 gttatactgt ggagcggaat cattctatta agtatagcaa caatgctttc tgcaaaaaga
    28441 tttaaacaaa acagatctct ctaacatttg aataatgtct gtgaacgcat ttttcaaata
    28501 aaaagaaata tccagaaaat gaccccaaaa taccagattg aaatctgata tttggggtcg
    28561 ttcatacttt atctttcttc atatttattt taagggatat ctgtttcttt tggaagatgg
    28621 ttcgggatct ttttcacttt caatacatct aaaaagaagg taaagatcgg aatgccgaca
    28681 atcaagcccc aaacgccaaa gaaccgttcg ctaacaagta agaccacaaa tgtataaaaa
    28741 atcggcagtt ctgttttgct ggacatcaac ttcggattca gcacataaga ctcaattaga
    28801 tggacaatca aaatcgtaat caggatataa acaacatctc ggatgcctcc ttgggaataa
    28861 gctatgaaag atagaggaat acaagaaatg ataacacctg ctactgggat cagacttaaa
    28921 atgaaaatca tgatcgctaa actcagcagc tgatgaaagc caaatacagc caaggcgatt
    28981 gtagtgagca acgtatttaa aagagcgaca acaaattgag cttctaatac caaaccaaat
    29041 gtattgacaa acttatcggc aaaatagtaa atatcttgaa agaaccaaga aaattcactt
    29101 tttaaaaaca atcttgagaa tacaattgtt tttttctttt caatcataaa aaagaaactt
    29161 aagatgaatg acatagcaaa cgccactgcc atttttccta tatcctgtaa atagccaagc
    29221 gcaatcgaag cgccattttg aagctgttca aaaaaatcgt ttcgctcaat ataagtatgg
    29281 atatattgta aaacaggatc tgcatctttt ggctgatgct cgtaaaaatt aataacggac
    29341 tggatcatgt caaatgtttg atgaataagc atcgggatat actttgtgaa tgccagatag
    29401 ataaggtaaa cgatcagtgt ataaatcatg atagctaaaa cacctgtagg gattcggaca
    29461 aatcgctgaa tgatttgaac aagatgaatc atcaaataag taaagataaa tgtgagcaaa
    29521 atggttgtaa tcatacttct aactaagaaa agaacaaaaa cgacaaataa taaaacagtg
    29581 agacggcgta ttttttcatt cgccaaaaaa cgctgataaa cggtcaaatc gacaacctcc
    29641 aaataacaaa aaataaacac gttattcatt atatgatgga atatgaaaat aagaaagagc
    29701 aaaaagaaaa accgctaaat gacgttatct tatgagttgg ttttcctcat aaaatcgttc
    29761 atctagcagt ttcagccctt tttctggtct tgatgaaaat tatctagcat ttttcgggtc
    29821 agatgttgca gtgtatccaa ttcttcctgt tcaagtggaa gataagactt gatcttttgt
    29881 ggaatacctt ctgcttgttt ttgcaacgca gcaccttgag cagtcagcgt aacatttacg
    29941 attctttcat cacccgtttc acgctgacga ttaatataat ttttttctgc taactttttt
    30001 agtaagggag tcagcgtacc agaatccaga cacaaatcat ttcctagctc tttcactgaa
    30061 gtctttttct tttcccataa aactaacatc acaagatact gggtataggt aagattcagc
    30121 ggcttgagga ggggagtgta gtgtctaatg atttctttag aggcggcata taaaggaaaa
    30181 catacttgat taactaaata tagatcttcc atttttccac ctccgctgtt ttactatagt
    30241 gtatcatagc ggatttacac aaaaaagtct attcactaac tgctttcaga gtaacttcta
    30301 tatttccagc tgtagctttt gaatacggac acactttatg cgctgcctct aataattctt
    30361 gcgtttcttc cagagaaaga ccttcgatag atccttcaat ctctacacct aagacaaagc
    30421 tcgtttcact ttctgaataa agggaaactt gtgcactgac agtagaagcc ccagagatat
    30481 ttttttgctg tttgatcaat tctaatgcac tgttaaaaca tgcactgaaa ccagctgcaa
    30541 acaattgttc agggttggtt gcattttcga cgcgtttacc aggagctgca atattcaatt
    30601 cgaatgtacg atcgggatta tgcacttctc cagagcgtcc gcctgtgttg atcattttcg
    30661 tagaatacat ttttttcata aaattaccac ctttaattat attttataca attgaatttt
    30721 acacaatata attgtggaaa gcaaagaaat ggattggcat aagataaata agagaaagca
    30781 catgaaacag acgcgctttc tcgaatagca aacatataca aaaaatatca gagacaaaaa
    30841 ataatctcat cataaacatt acatatattt ctcaaaaagt tgttttcttt cttcaaaaat
    30901 tacttcacga tggacctgat gaagcatcca taaataacca aaaggatctc tgaacattga
    30961 gttagtcaca ccaaagtcca tcatttctgt catttcttga atctctacac agccatttcg
    31021 taatgcttta ttatgtgtgt cctcgatatc agagacgatg atattgaacc agatcgtatt
    31081 tggatgttca gcagtaggag cagtcaaacc aagagacgtg ttttcatcca gcatatggaa
    31141 tctcgtacca tacaaggtaa aaatgacttc attattgcct ctagggtaat ctgttgcctc
    31201 aatcagttgt atttcatcaa agattgtttg atacagttct agtgctttca aactatcatt
    31261 taatacaaaa tcgatttccg ttcctttatg cataaagatc tcctctcctt ttcagtcgaa
    31321 cagttactag attcttttat tataccagct aaagaaaacg cattcaaaaa aatagcggat
    31381 ttacttacca actcattcga ttggatgata agtaaatccg cgtcccatta cttctgctac
    31441 gctgctgaca atgacaaagg cacttggatc gatttcttct atcaatggtt tcattcggga
    31501 aaattcatga tcagtcacaa cgatcaataa aacctctttt gactttcgat tatacccgcc
    31561 ttttgcctct agcagggtaa ggccacgtcc aatctcagca cttaagcgaa ggcggatgtc
    31621 ttccaaataa tgttcactca tgaccataac agatttcttt cgattgatac ctgtttcgat
    31681 ataagtcatg acaattgaag tgattgcaat agataaaata gcataaagaa actcttctat
    31741 tccaaaaata aacagattaa gagaaacaac gaatgcgtct gtaaaaaata agccaatcga
    31801 agtattcaag tggaaatatt ttttaaaaat gaggggaggg atcgtcgtac cgccgctaga
    31861 agagttgttt ttatataaaa tcgcaactcc taaagcaaaa atcgcacttc caaaaatgac
    31921 agacaacaac cgatctgaag taatcattgt ttctggaact attgcaatga ttaaaggaaa
    31981 aaccaagctt ccgaaaagta ctttaaaaaa gggtttttta cctaaaaata gaagagctag
    32041 taccaacata acgatattca acactaaaat aactatagct cggtcaaagc ctaaagcagc
    32101 ttccagtaat attcctagac cgctgacacc tccagcagca atatgatgag gccctaaaaa
    32161 catattgata gcgactccta atatgaagag ggcaaaaata atcttaatgt atgtccatat
    32221 aaattgtctc gtttctttca tttattcact tccttaattc attaataata ctcttatctt
    32281 attataactt acttttcacc ttaagttaac tttaattaat aaaaaaatta ggctagtcta
    32341 aattattatg tttcattctt ctagaatata cttctacgcc aaaaactgtt aaaaaacttt
    32401 tactttagaa aattggagaa attgatcgct taagataaat tcaggacact aaatagtaca
    32461 ggaagtagac taaaactttt aaaagtttta agtctatcta tttggcaagt ttaaaaaata
    32521 aaaattcggt atcaaaaaac tgttaccgat aacatttttg aaagcgttgt cttttgcttc
    32581 tctatcactt atagtgatga cgtcatatta aaacacaagg aggaaatcaa tggatacagc
    32641 tgcaatttat catcgaccgg aaagtgaata tgcatttcta tatacgaata caagatttcg
    32701 tattcggctt cgtactagga aaaatgatat caaaaaagta tatgtgctat gtggagatcc
    32761 atataccata acaactgaaa aatggtatca aaaacaacga ccaatgaaaa aatgtctaag
    32821 taccaatgtt catgattatt gggaaattga agtgacgagc gaaacaagtc gcttacagta
    32881 tgcgttccat gttgttgggg aagataacac ggactgtttt tacggtgatc aaggaatttt
    32941 tccttatcga gaaaatgtga ttactgaacc aaatttttat tttcgaatac cttattttca
    33001 tcaaatcgat cgattcacta ttccagaatg ggtaaaagaa acagtatggt atcaaatttt
    33061 tcccgaaaga tttgcaaacg gggacaaagc aaatgacccc gaacacactt taccttgggg
    33121 aagtaaagat ccagaccgag aagacttttt cgggggagat ttgcaaggtg tgatggatca
    33181 tttggattac ttgacggacc ttggcatcaa tggcatctat ttttgtccca tatttaaagc
    33241 cacatccaat cataaatacg atacgattga ttattatgag gtggatcccg cttttggcga
    33301 taaaaaactt ttaaaaaact tgattgatga agcacataaa agagggatac gtatcatgtt
    33361 cgatgctgta ttcaatcata tgggtgtcca ttcaccacag tggcaagacg ttctcaaaaa
    33421 cggagaaaaa tcgatctata aagactggtt ccacatccgt tttttcccag tagattctta
    33481 tcagatgact gacttaccag aaactgctga aaatatccca tatgatactt ttgcttttac
    33541 tccattcatg ccgaaactaa atacagcaaa tccagaagtg caaaaatatt tgctggatat
    33601 cgcaacttat tggataaaag aattcgatat tgatggatgg cgtcttgatg ttgctaatga
    33661 agtcgatcat catttttgga aaaaattcag agaagcagtt acagaaatca aaccagacat
    33721 ctatatcctt ggagagattt ggcattcctc tcaagcttgg ctgcaagggg atgaattcca
    33781 tgcagtgatg aattatgcat ttacagattc gattaaagat tattttgcaa aaaagaaaat
    33841 cacagcttca caaatggtca gtggaatgaa tcatcagcaa atgctttaca gagatcaggt
    33901 gaacgaagga acattcaact tattagattc tcatgatact gccaggatct tgaccctttg
    33961 ccaaggtaac aaagaattga tgaagtctgt gatggccttt atgtttcttc aaaaagggtc
    34021 tccttgtatc tattacggga cagaaatagg gatgactggt gaagatgacc cggattgccg
    34081 caaatgtatg atatgggaga aggaggaaca agatctagag ctattcggtt ttataaaaga
    34141 acttgtttct ctaaggaaac agttgtctaa gattatttct gaaggttcta ctcagtggct
    34201 aatagtaaat gatcgtgaag ataagctcta tttcacacgg aaactagagg gacagatcat
    34261 ctatgtttac tttaatcagt caaaagaacc ttgggtagta gaacaggaaa atgaggtgat
    34321 tcttagtcaa aattgtcagt tgttagaaga cgggaaagca gagatacgac aatacggatt
    34381 tttgatcatg tgttgaaaac tgttaccggt aacaacaaga aagcgtttgc aaatgaagat
    34441 ttgtgcccat tataataagg gtgtaacagc acgttgaata caaaggagga aatgaagatg
    34501 aaaaaaagaa gtgtgaaaca gttgggttta gggttaatct ctttaggaat cttaggcgga
    34561 ttagcggctt gtggcaatgg taactcttca gcagaagggg aagccgatga aggaaaaacg
    34621 ttaacagttt ccgttgattc tggatataaa gattatataa acgaaataaa aaacactttc
    34681 gaaaaagaaa acgatgtgaa aatcaagcta gtagaaaagg acatgttcga tcagttggaa
    34741 tcattagcgt tagatgggcc tgctggaaag ggacctgacg ttatgatggc agcatatgac
    34801 cggatcggtg cgttaggaca gcaaggacat ctggcggaag taaaactggg aaatgaagca
    34861 gcttacgatg aaacagacaa agcccaagtg acttatgatg gaaaaatcta cggagaacct
    34921 gcagtaatcg agacccttgt tttgtactat aacaaagatt tagtcgatac agcaccatca
    34981 acgtttaaag atttggagaa tctatccaaa gacagtcgtt ttgcttttga gtcagaagca
    35041 ggaaaaaata caggattttt agctaaatgg actgactttt attattccta tggtttaatt
    35101 gcaggttacg gtggctatgt atttggtgat gatggcacaa atccttcaga tatcggtttg
    35161 aataatgcag gtgctgtaga aggaatctct tatgcaacag attggttcaa aaatgtttgg
    35221 ccaaagggaa tgcaagacat aaaaagtgca ggagacttcg ccagccagca attcatgtcc
    35281 aataaaactg cagcaatcat tgacggtcca tggcaagcgc aaacatacaa agaaaacaat
    35341 atcaattatg gtgtagccaa aattcctact ctaaataatg gacagcctta tcaaccgttt
    35401 ggcggaggaa aaggatgggt agtcagcaat tatgctaaaa acaaagacct ctctcaaaaa
    35461 tggcttgatt atgtaacgaa tcaggaaaat caagaaaaat tctttgaaat ggtaaatgaa
    35521 atccctgcaa accaacaagc tagggaaaca gcaaaggcta aaaacgatga attaacaaca
    35581 gctgtgattg aacaatatga aacagctcaa gcgatgccaa acatcccaga aatgggcgaa
    35641 gtttggacag gtgcagaaaa cttgatgttc gatgcagcat caggttcaaa aacaccaaaa
    35701 gaatccgcag atgaagcagt aaaaacaatc agtgaagcca tagaacaaaa atactgatta
    35761 aaatgataac cgtccatttt tataaaaaat ggaacaggtg cttcagataa aagtggcaag
    35821 agcgagatgg aaaattatct tgctcttgtt gccattatct taaaagcagt ttgcggttta
    35881 gcaagtttag agggggcatt cagatgcagc aagataaaac aagcaatatc aacgaaaaaa
    35941 aaatcacgct ttgttcactt attccaggga tggggcagtt tgtaaatggc caagctttta
    36001 aaggtatcgt ttttttcgcc atattcgtcc tattcattgg tcagatgctt ctgggcggat
    36061 ttcatgcatt ggtaggattg gttactttgg gaagtatacc aatggaagat cattcattat
    36121 ttattttgat tgaaggcact ttgcaattca tcattacaat cattttcttg attttttacg
    36181 gtttgaatct tttagacgct tatcgagtag cgaagatgcg tcaagagggc aaaaaaatca
    36241 atcggacgat gaaggaagtc atacataata taggtgatga aggttttcct tatctattga
    36301 cacttcccgc ttatcttctc atgattttta cgatcatttt cccagtccta gttacattgt
    36361 tcactgcatt tactaattat gacttcaatc atattccacc agccagttta attgattggg
    36421 taggggctaa aaactttttt agtatcttct ttttaagctc atatcgtaat actttttttg
    36481 cagtcttttc gtggaccgtg atttggactt tatgtgcaac aactttgcaa atcacccttg
    36541 gtattctcac agcggttgtt gctcaccaga aatttattaa attcaaacgt attttcggta
    36601 tcattttctt attaccatgg gcggtcccag cttttattac tatcatgagt ttttcgaata
    36661 tattcaacga tagcgtaggt gccatcaata ctcaagtgat tcctttcata aaccagcttc
    36721 cttttgtaga tatcagtgca atctcttgga aaacggaccc gaactggacg aaagtagcaa
    36781 ttatcttagt gcagggctgg ttaggatttc cctatatcta tgtgatggtt acaggaatct
    36841 tacaatcgat ttcagaagac ttatatgaag cagcaaaaat cgacggagca aatgcatggc
    36901 agcgcttttc aaacatcacg cttcctgctg tcttcctagt ggcagcgcca acatttatta
    36961 cacagtatac ggggaatttc aataatttct ccatgatcta tctgtttaac aatggcggtc
    37021 ccggaagcgt aggcggagga gctggttcta ctgatattct tatttcctgg atctataaac
    37081 ttacgactgg aacttctccg cagtattcta tggcttcagc aatcacgttg attatctccg
    37141 tcatcgttat ctgtgtgtca ttgctggtat ttaaaaagac aaatgcgttc aatatggggg
    37201 attaacaatg aaaaaatttc attcgagtgc tcgattccaa aaacgacttt ctcacttttt
    37261 tacttacttt tttcttttaa tactgtcagt cattatcatc tatccgcttt tgatcacagc
    37321 aagtactgcc ttcaagtcag gaaatattgc agcttttagt ttagatcttt caagtgactg
    37381 gactttagga aactttactc ggctattcag tgaaacactt tacgggactt ggtataaaaa
    37441 tacattgatc atttctgtcc taacaatgat cgtacaagtg actgtagtaa ctttggcggg
    37501 ctatacttat agtcgctatc gttttatcgg ccgcaaatca agtttgatgt tctttttagt
    37561 gattcagatg gtaccgacta tggcagcatt gactgccttt tatgtcatgg ctttcttatt
    37621 agaagcgctc gataagtact ggttcttgac aatgatctat ataggcggtg gaattccaat
    37681 gaatacttgg ctgatgaaag gatactttga cactgtacca atagatttag atgaatctgc
    37741 taaacttgat ggggcagggc atttcaggat ttttttccag attgtattac cgcttgtcaa
    37801 accgatgctc gccgttcaag cattatgggc ttttatggga ccttttgggg atttcatgtt
    37861 agctaagttc ctgcttcgaa cacctgaaaa tcagactgtt gctgtcggct tacaaacatt
    37921 tatttctgat gtgacaaacc aaagagtctc tctttttgct gctggggcaa ttttgattgc
    37981 actaccgatt tgtctattat tcttcttttt acaaaagaac tttgttaccg gcctgacatc
    38041 tggcggaaca aaaggatagg agcagagtat catgcaaaca tttccgttaa actatttttc
    38101 cgcattacgt acgccaactc aagtgtttgc gggacgcaaa ctattatcat ggcctaaatt
    38161 tttcttgata tttgtatttt tagtttcctt gatggtcatg cctgtgactc ttttttatgc
    38221 caatcagatc caagcgattc cattagaaca atttctatcc gttcattcgc tgatcgatga
    38281 acaaggaacc caaaaatttt ctgaacttga attatctgaa actgggttac aagcatcgca
    38341 acaaacgata gctgtgaccc ctgaaatttt ggtaggtgtg tctttatctg agaaacaaca
    38401 atccgatcat ggaactttta ttgattttga gaaggaacaa tgggtgatcc aacaaaagga
    38461 taaatctggt atacgccgct atacgatgaa ttatagccca tctttccaac cagattctgt
    38521 acgtacgccc gaagatttcc aacgattttt agaaagagaa ttttatgcca gtaatcgtcc
    38581 aacaatcatt ttatcttata gtttaagtct tggtcttgtc ctatttgtca tgacgagtct
    38641 cattttattc ggggcttcct ttttcttgtg gatgacaaga aaaagccaac tttcatccat
    38701 tcatacattc aaagagagtg caaatttgat gctgaatgtt atgggaatag gttccatggc
    38761 agcagcagtt gtagggttta tccactttga ctttatcttg atgctaagtg tccaaacaac
    38821 gataactgtc ttgctgcttt tatgggtttt tgtcaaaaca agattcaaag ataagcgtgt
    38881 cgaatgacaa gtttaagcga tttatgcgac aatgaatgtg aaaaaaatga aaaataaagt
    38941 agtttttgaa aaatttctga aaaaattaaa cttcttagtt gattcttttc ttttttagta
    39001 ttaacgtaat agggtagttt ttttaaggag gaaaatcatg ttagagaaaa ctttatacaa
    39061 tcaattattt tcacgttctt tctcgctccc tgtcgaagta aattattggg acggtacaac
    39121 gaaacaatac ggagatacgg acactcctcc ccaaatcaaa atcaatatcc atgaagaaat
    39181 cccaatgaaa gagattacaa gtaacgcatc tttggcacta ggagaagcct atatggatca
    39241 tcgaatcgag atcgagggaa gtatccaagc attgatcaac gatgcttatc agcaagcaaa
    39301 cagcttttta cgaggaaaag attatctaaa atggctgcca aagaaagaaa aacatacgaa
    39361 acaaaaaaac aaagaagata tccatgcgca ttatgactta ggtaacgact tttataaact
    39421 ttggctagat ccaactttga cttattcttg tgcttatttc aatacacctg aagatacgtt
    39481 ggaacaagca caaatcaata aagtccatca tatcttagac aaactcttta tcaaagaagg
    39541 cgaaacgttg cttgatatcg gttgtggctg gggaacattg atgttcactg ctaccaaaga
    39601 gtataatgtc aaggcaactg ggatcacact aagtgaagaa caatacgatt tgattaccaa
    39661 aagaataaaa gaagaacatt tagaagataa atgccgtgta ttattaatgg attaccgcga
    39721 actaaaaggc gaaacgtttg atcatatcac aagtgtaggt atgttcgaac atgtaggttc
    39781 tgaaaatctt gaaggttatt tcaaagtggt aaaagattta ttgaaaccaa aaggaacagc
    39841 tttgatccat ggaatcagcc gacaacaagg cggtgcgaca aatgcttgga tcaataaata
    39901 tattttccct ggcggttatg tccctggtgt tactgaatta gttgataata ttacaaaaaa
    39961 cgatttgcaa ctgattgatt tggaaagctt acgtcgtgac taccaattga cattagaaca
    40021 ttggacaaag aattttcatc aagtccaaga tcaagtcacg aaagaaatgg gtgattcctt
    40081 ctatcgaatg tgggatctat atttacaagc ttgtgcagct tcatttgaat caagtaatat
    40141 cgatgtgatt caatatttgc ttgttcaacc tggaaacaat gacatcccaa tgcatcgtgc
    40201 ataattgagg caaaagtact gtttaaagac tatttaaaaa gaagctaagt tttatgatgc
    40261 tccagaagtg aacttttttg tctaacttct aggattgtct ctaaagctta gtttcttttt
    40321 ctttatattt tcataataaa agtttggttc tttaattttt aaacatgaca gaaaattttt
    40381 tcttcg
//
LOCUS       DADQDV010000021        37016 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.021, whole genome shotgun sequence.
ACCESSION   DADQDV010000021 DADQDV010000000
VERSION     DADQDV010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 37016)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37016)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37016
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.021"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            2..74
                     /locus_tag="J8S10_001146"
     tRNA            2..74
                     /locus_tag="J8S10_001146"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35..37,aa:Asp,seq:gtc)
     gene            78..150
                     /locus_tag="J8S10_001147"
     tRNA            78..150
                     /locus_tag="J8S10_001147"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:111..113,aa:Phe,seq:gaa)
     gene            155..225
                     /locus_tag="J8S10_001148"
     tRNA            155..225
                     /locus_tag="J8S10_001148"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:187..189,aa:Gly,seq:tcc)
     gene            238..311
                     /locus_tag="J8S10_001149"
     tRNA            238..311
                     /locus_tag="J8S10_001149"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:272..274,aa:Ile,seq:gat)
     gene            323..394
                     /locus_tag="J8S10_001150"
     tRNA            323..394
                     /locus_tag="J8S10_001150"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:356..358,aa:Glu,seq:ttc)
     gene            660..1853
                     /locus_tag="J8S10_001151"
     CDS             660..1853
                     /locus_tag="J8S10_001151"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HAZ9629741.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            1983..3455
                     /locus_tag="J8S10_001152"
     CDS             1983..3455
                     /locus_tag="J8S10_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAZ9629742.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            3538..4326
                     /locus_tag="J8S10_001153"
     CDS             3538..4326
                     /locus_tag="J8S10_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HAZ9629743.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(4393..5061)
                     /locus_tag="J8S10_001154"
     CDS             complement(4393..5061)
                     /locus_tag="J8S10_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HAZ9629744.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQKMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            5176..6888
                     /locus_tag="J8S10_001155"
     CDS             5176..6888
                     /locus_tag="J8S10_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9629745.1"
                     /translation="MKLILRHAKKYKVSVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            6891..8663
                     /locus_tag="J8S10_001156"
     CDS             6891..8663
                     /locus_tag="J8S10_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9629746.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENGKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
     gene            complement(8745..9866)
                     /locus_tag="J8S10_001157"
     CDS             complement(8745..9866)
                     /locus_tag="J8S10_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAZ9629747.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLSLISKYIKDD
                     VLVKNVNSNLIQDMLDYYYFEKNLSYNYVIHLKTFTGMIFKFANRRYGLKYNPVNGVS
                     LARKPKTNEEIKKEKDGYLSKEEVQMIASKQKSSHQQSRYSLITKFLFLTGLRYGELI
                     SLTESDYDGNKITVSGTYDYELKIKTTTKNTGSYRTIELSSNAKEIIDQLIEENKLIK
                     NNKDKYIFISKNGNPISIQAYNQSLRAVSKELNLDKKVSSHMLRHSHISLLTELGIPL
                     KAIMDRVGHEDSKTTLKIYTHTTKNMQNQLVEKLGKIEI"
     gene            complement(9938..10870)
                     /locus_tag="J8S10_001158"
     CDS             complement(9938..10870)
                     /locus_tag="J8S10_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HAZ9629748.1"
                     /translation="MLKLKEKEYIIDDAVSVPLILNKREKNNLKKKMLIPFDSEVKGL
                     LNKLTISNIDSTREKIIKIFDKINNLFKNDNAELRKGLLEFKLQELELHYSYLVKITE
                     EKEQQKAIKEQMIEEEKVRREIDREKKRIDKEQRQFNSEISKLIAYMQKANADVEKEL
                     YANKIQELEEKLKELEVIRENVLQRELNTRAGYVYVISNIGSFGEDIYKIGMTRRLEP
                     MDRIKELSSASVPFEFDVHAMIFSEDAPSLETKLHNHFRKQEVNKINQRKEFFKVSLD
                     EIEKVVLENYNGTVTFTKLAKAEQYRRSLELSKD"
     gene            complement(11309..11761)
                     /locus_tag="J8S10_001159"
     CDS             complement(11309..11761)
                     /locus_tag="J8S10_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HAZ9629749.1"
                     /translation="MHLNKYWILEEIEKLFVEFGSDAINPYKIIKYSDIDLIETDLGN
                     KTLGQTIHNKRCYVILINQNLSPSMKRFVLWHEIAHVRLHKGICTAAFRANNLSCMIY
                     GIEAEANMFAIEMLTRTIDEQDLSDMSQFQIIEYLGLPHNLEHLVLQH"
     gene            complement(11774..12184)
                     /locus_tag="J8S10_001160"
     CDS             complement(11774..12184)
                     /locus_tag="J8S10_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAZ9629750.1"
                     /translation="MLLDRIKILLKERSMTLAELERKLNFGNGSMSRWNKSTPSGDKI
                     QKVADYFNVSTDYLLGRTDKRHYYDLTEKDKQDIALQAEKLLEGLNSDAETNYYGEPL
                     DDEDKEKLYDAIQLALALTKVKAKKKFTPKKYRQ"
     gene            12459..12671
                     /locus_tag="J8S10_001161"
     CDS             12459..12671
                     /locus_tag="J8S10_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAZ9629751.1"
                     /translation="MTLKQQVLIALVKKGWSQRELARRMGISITYLRDIFIEKRKPKE
                     RLKQIEELLDIKLEVDSNDQPSEQEA"
     gene            12674..12886
                     /locus_tag="J8S10_001162"
     CDS             12674..12886
                     /locus_tag="J8S10_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629752.1"
                     /translation="MVQRLSKAEFKEKYKYSESTYQRRMKEFKKSRFSEGYNAVTSKE
                     ITIDVDLYEQFRTWRSKNRFRVRAVC"
     gene            complement(13178..13402)
                     /locus_tag="J8S10_001163"
     CDS             complement(13178..13402)
                     /locus_tag="J8S10_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004401476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HAZ9629753.1"
                     /translation="MGKNQHVVPNSNGGWNVKGAGNSKATAHTNTKSEAVKIAREISK
                     NQGSELFIHGRDGKIQSRDSHGNDPHPPKG"
     gene            13480..13668
                     /locus_tag="J8S10_001164"
     CDS             13480..13668
                     /locus_tag="J8S10_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629754.1"
                     /translation="MAYTLQQEHQILGLIKQRRKQLQDDRAALRKADELSDRQAELIA
                     SELEDLRMLEIKNREIRL"
     gene            13994..14329
                     /locus_tag="J8S10_001165"
     CDS             13994..14329
                     /locus_tag="J8S10_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629755.1"
                     /translation="MNKKIENLIEELKRECQKQGVSIICTAQKEGELKSLVYGETTEI
                     LLCLAMQEEHLDENLPLSAHIMRRIAVDAYEQAKNEEENQPSNHTFVINNKEDLADVM
                     TRILKGEFQ"
     gene            14562..15503
                     /locus_tag="J8S10_001166"
     CDS             14562..15503
                     /locus_tag="J8S10_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease"
                     /protein_id="HAZ9629756.1"
                     /translation="MSKSTLEMSHQEWLEDRKKGIGGSDVGTILGLNKWKSPYQLWLE
                     KTGQVVLEESGSEPAYWGNVLEEVVAKEFQERTGKKVRRRNQVFEHPLHPFLRANIDR
                     EVVGENAILECKTANQFLGKEWEGEEVPLSYLCQVQHYMNVLNKDYCYIAVLIGGQKF
                     IWKRIERDQELIDTITEQLVEFWETNVLGGIEPIIDGSQATADFLKEKYADVEDVQTT
                     LPIHFDELVEQKNELKRTKKEIESAIRQVDNEIISELGKREASIGITQKNIISWKFVR
                     TRRMNSKKLAEKYPDVANDEEIYNVTESRRLTEREIK"
     gene            15505..16395
                     /locus_tag="J8S10_001167"
     CDS             15505..16395
                     /locus_tag="J8S10_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HAZ9629757.1"
                     /translation="MATNESLKNQLAAKPQKQVAPGQLGLKALMNTPTMRKKFEEVLH
                     DNANAFMSNVMTLVSNDSYLADSEPMSIMSGALTAATLNLGLDKNLGYAYLVPFNSKN
                     KQTGKWEKKAQFMLGYKGYIQLAQRSGKYKALNVIEVYEGELKSWNRLTEEFEFDPNG
                     RTSDEVIGYVGYFELLNGFKKTVYWTKQEIEAHRIANNKDRDKTKLSGVWASDYNAMA
                     RKTVLRNLLSKWGILSIEMQEATTSDERVQRVQEDGSIIAETEVEEDIPERKEAEVIS
                     EENEDVQTGLFDASNPPLNK"
     gene            16438..17238
                     /locus_tag="J8S10_001168"
     CDS             16438..17238
                     /locus_tag="J8S10_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HAZ9629758.1"
                     /translation="MNTGYVKLHRKVMNSFVWTNPYMYKLWNLCLMKASHENRKILFN
                     GKEIQVNSGEFVTGRDAITSEMNEGVKREHQVNSGSVWRWLKQFEKNGMLNIKSTTKY
                     SVISIKNWSLYQSSEQQMNIKRTTSEQQVHTNKNEKNYKNEKNNKTSSSQPRKKRVYD
                     TDSVYYILAEELFKQICQNQEIKKPNLQSWADDIRKMIEIDKRTENQVRGMIEWSQHN
                     VFWASNILSAKKLREKYDTMAAQANRDYKTKQTKTLEYEKFSTDELPI"
     gene            17253..18104
                     /locus_tag="J8S10_001169"
     CDS             17253..18104
                     /locus_tag="J8S10_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAZ9629759.1"
                     /translation="METVGEIMEKLIQKVLVQRGECPECGQPLYGWRTKNPDGSERCK
                     PTCMQCGYKALRVQEDLQTERIYNESLKARAINFFKGGSVVPNQALFDCTLQNYQIVD
                     QETRQAVEVTKRFVNSVLLGNPSHLVLTGKQGTGKSHLAMAAAWEVLKRSNYDKKILF
                     IGLQEMLDQIKFSYNNPELRKTIEGSLIADIKTADLVIIDDIGSELGKDASDSRAFGI
                     NTLNSFLDARQNLATIITTNLLGEELKKAYGTRTISRMFVNSDGFTMVFSQTADKRIK
                     PVKGAIA"
     gene            18305..18766
                     /locus_tag="J8S10_001170"
     CDS             18305..18766
                     /locus_tag="J8S10_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010781228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAZ9629760.1"
                     /translation="MPKILDACCGSRLFWFDKNNSDVTFMDCRQQYEELSTGHVINVD
                     PDVVADFRDMPFEDDVFDMVVFDPPHLRHVGENSWLAKKYGKLDELWPEDIRQGFAEC
                     MRVLRPSGTLIFKWNEEQIPLSDVLEAIGEQPLFGNKRSKTHWLVFMKKFS"
     gene            18792..19244
                     /locus_tag="J8S10_001171"
     CDS             18792..19244
                     /locus_tag="J8S10_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629761.1"
                     /translation="MKIVLNKCFGGFGLSHEAKMEIFKRKNIEVFPYINNFSYDSDDE
                     YTRYTGQKLGSMDFIYYFKKDPKIDKVTGIYSEIDRLYGIADDSSFSSDSNRGDKDLV
                     AVVEKLGSEASGPYASLKVVDIPDGAEWEISDYDGVETAHYGFQTGSI"
     gene            19350..19544
                     /locus_tag="J8S10_001172"
     CDS             19350..19544
                     /locus_tag="J8S10_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629762.1"
                     /translation="MDASEVVNKINSLKEVFGDVEVVINAQGYDNEFFKQITDISIQQ
                     GMEDEDGNFIDEVAILVTCE"
     gene            19575..19868
                     /locus_tag="J8S10_001173"
     CDS             19575..19868
                     /locus_tag="J8S10_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629763.1"
                     /translation="MKLKDGFYSSGHGIGGLMLDMPTKNPKTRKKPKFKVGDMVRCEA
                     EGFIYPFRGYVEHVYNHSAIIRIENTMECDKWLAKSKENLAVVRLVDMEVIKS"
     gene            19898..20338
                     /locus_tag="J8S10_001174"
     CDS             19898..20338
                     /locus_tag="J8S10_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAZ9629764.1"
                     /translation="MSVIPQLEGEEAIVNILENIDIKQTRKNARRLLKRYRNLERLVG
                     PVKIDFSVMTVTKNLKFTIDSQNEEIIEAISTRDSVIEALTRLSRIHFQVLYYSYCFP
                     NKMSMYQIGEKLGYSDRTIERMKAVALVEFAEAYKSGELISRTK"
     gene            20413..20880
                     /locus_tag="J8S10_001175"
     CDS             20413..20880
                     /locus_tag="J8S10_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HAZ9629765.1"
                     /translation="MVLFDVKKYETPSAKDVDMERTKHNVAVFLSAYLSARCRVGQHR
                     EPKVTASYSLVPPSTADHIFEAERMLIDKEEAQEEFEYLHKLFVRGYSAIQHPHKPDV
                     TERRKKIFYDRYINGLPIYVTAQRNNTSEESVKVESNRIIIQFASSLELVAFK"
     gene            21627..21857
                     /locus_tag="J8S10_001176"
     CDS             21627..21857
                     /locus_tag="J8S10_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629766.1"
                     /translation="MRNYWYVSLTNEYPRTIDDCSVRVVRSVQIKGKYSIVEMGREAE
                     PCEIDACKLVYCGHGFYDEPNIQNNINKNLRD"
     gene            22016..22849
                     /locus_tag="J8S10_001177"
     CDS             22016..22849
                     /locus_tag="J8S10_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small subunit of terminase"
                     /protein_id="HAZ9629767.1"
                     /translation="MARQRDPRRDEAKRIWLESNGEKQLKEIASELNVSDSQVRKWKS
                     QDKWSAELISNVTNGKSNVTNQGGAPIGNQNAKGNKGNSRASPPVGNKNALKTGEYET
                     IFFDTLTDNEKDIYSSLNDDPSFALSEEIRLLKIRQLRMMKRIQQAEAGLNDEEVERL
                     QQLRKIKTPIEKNGKKLEIKREVMQDVQISRKKHRKIDDILSIEDSLTRISNQLAKAI
                     KQMNELYMNEYRTDLIKAQTDKIQAETNEIGGNNSGEEIEEWKQAVLNAANKRAVKEN
                     E"
     gene            22842..24257
                     /locus_tag="J8S10_001178"
     CDS             22842..24257
                     /locus_tag="J8S10_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAZ9629768.1"
                     /translation="MNNEFIPFADIGSAIDYYYDKPVAFCQDILHLNPDEWQENVLND
                     LAEFSKVSVRSGQGVGKTALEAGAILWFLTCRPYAKVIATAPTMKQLYDVLWAEVAKW
                     LNDSLIKNLLKWTKTKIYMVGDSERWFATARTATKPESMQGFHEDHMLIVVDEASGVS
                     DPIMEAILGTLSGFDNKLLMCGNPNNIEGVFYDSHNSDRDKYRVHKVSSYDSKRTNKD
                     NIEMILKKYGKESDVARVRIFGEFPKGALDSFISLETVELATEKQISDSLVNKTKVAH
                     IGVDVARYGDDSTILFPRIATRALEYEKYSKRSTMETTGYVINMAKNLMSQYPSIDKV
                     MIKVDDTGVGGGVTDRLEELIEDKHYPFEVFGVNNGSTSEDDFYDNLGTQLWGNIKEM
                     LEENMTANLNGEQPVIELPSDSSLIKELSTRKFKMTSRSRIRLESKDDMKKRNIGSPD
                     IADALALAFYEPPSHYQFIQF"
     gene            24269..25798
                     /locus_tag="J8S10_001179"
     CDS             24269..25798
                     /locus_tag="J8S10_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAZ9629769.1"
                     /translation="MISTVLSLERYKKLRVKYATQIEDGMFDPNGFIEDMKPFFADRE
                     RKYLAYTSEKNEIDNRPKPNTDIVKVNNKLHAGMYSIVVDQAVNHFTGIPIKWDYDVS
                     EQKRTLIQRLKDKFLKNDIELPTVPEAFNKLTSNLDSMRFAMLDSETATFQGACGVAF
                     RLLEPVEEDDGWKLRASNIEPWRAERYGNAGIYIKEKYDSYQKKFFQEMKVMTRNKIL
                     TYACYGDLNFVTSGTFKKIDETDNPLGTITLAEFKNNTNRYCDFEVAEEIGDAIDRAL
                     SDQQNEIEQFKLAYMLVTGTTMSKGTAKEMMNQLGIINLKAPTAKAEYVTKNLAKDFN
                     EYHMDLLKKQFYTICKAIDFNDEVFKSNSSGEARKWQIISLEAKTNTKEQYFREGLKE
                     CAETIAAFLKFHDKVEIEPEKIIFTFSRSLPTDLSYLAEALPKLAPYVSKRTIQSQIP
                     FVTDVDYENEMMELESGSAYPDSEYNFGGGGNSDDRNEVLDQTSRTGGSSKAQTRKSD
                     T"
     gene            25890..26768
                     /locus_tag="J8S10_001180"
     CDS             25890..26768
                     /locus_tag="J8S10_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HAZ9629770.1"
                     /translation="MMEFYSTSNQKKYREYVEKNYKSLKMYDAKYKEFIDEFFPPFDY
                     AKVNRLLQIRSDVFKILAEYAMDADVNQYFSDRLEEILQRTYSSNANVFVQLLNVDIP
                     NYLPENEIKHYLNYPWSGKTFSRRLWGNISSLEQKLSNAIVKSVASGEGVIHALNTMR
                     LDSEICDMFKLEESKYNKAIENLVRTEYAKFAQDGIEKSYLETGIEEYNVLTAKDERV
                     CRICGGKASKNPYKLKDAVIGENRAPFHSRCRCTDVPNLPKLGKDIDEEYDRLFGDLL
                     DEFAHDSFGINLKRRK"
     gene            26770..27087
                     /locus_tag="J8S10_001181"
     CDS             26770..27087
                     /locus_tag="J8S10_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629771.1"
                     /translation="MKDFFEAVLTINVNADIAEAYKTAIESENHPNGLRDHWNGNYAY
                     VVIGDQTVNYQDNTPVDKNTVNLTIQLLSHSLPNLKETVDWYEKMGCIVVRTDYKEGK
                     SSN"
     gene            27136..27837
                     /locus_tag="J8S10_001182"
     CDS             27136..27837
                     /locus_tag="J8S10_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HAZ9629772.1"
                     /translation="MVEWWGATIKTQSNAGRENESWGERRMSMKHKSLMPMNLQYFAE
                     GDDQKFSFDDFKSFVESNEEAQKFIQSQSQSVADKQLEAWKQNNLDKIKQDTIKEYEE
                     SKKNKSPEQIQLEKLQAEFEAEKALRVTSDNKAFVAEQIAGLELDGELKESISQFMLN
                     NLVSSDTDFTKNAVEGFTSVLNAINEKHADALKELQMKSAFGGTQQSNNQVQQNNETL
                     TNPEEQLGQILQQFN"
     gene            27852..28742
                     /locus_tag="J8S10_001183"
     CDS             27852..28742
                     /locus_tag="J8S10_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5309 domain-containing protein"
                     /protein_id="HAZ9629773.1"
                     /translation="MKKTSLNNLEYLDISPAINAMQVPNTPFLSYLLGAGKTEPANST
                     EIKWREYDINNDDSSEKLEGGEYPDAESGRTWFNNYTEIFRKSTSVSGTLDAINVNGV
                     GNELTNQVALRGMEMKIDLNRKLITGVKADENGSKGRRMNGILNLINSANKAETATAG
                     AVTRKDIDTLFKLMYEKGYMGEKLCLISPDMQELMTDELDGKSTKIVQFGERVTFGLQ
                     IGNIVSNYGTGIALLEPSLPKGTIAAIDTNYVKLRPLREWRAEELAKTTDSRRIGLVG
                     EYSLEYNASNSGAILNLKSE"
     gene            28765..28980
                     /locus_tag="J8S10_001184"
     CDS             28765..28980
                     /locus_tag="J8S10_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629774.1"
                     /translation="MIGGITVVKKDETKKDEVVKYRVGKTKNFVGFVHPKTRRFITAD
                     SNNEFIISIDDKEAIAILEDAIDVNEI"
     gene            28992..29333
                     /locus_tag="J8S10_001185"
     CDS             28992..29333
                     /locus_tag="J8S10_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629775.1"
                     /translation="MDESLKTEIIESTKEDFPDLSEERITNLLEIILLEIESYNTCKN
                     DISWEKLKSVISEVLYKIIKNESEKTVSSVRRGDTTISYASTTNDVSELLLGYGDLIR
                     RVIGCGGLEFF"
     gene            29333..29704
                     /locus_tag="J8S10_001186"
     CDS             29333..29704
                     /locus_tag="J8S10_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629776.1"
                     /translation="MNEADILETTYEDSCIIERLTDIEDSNTNITIQDYKKVYDNPIS
                     CALSQGQIDGLAVIEDGEMVNVSTDTYKLFVHPKIKLKKGDRITITQKASGLIFSLFA
                     TKPFYYPSHCEVNLIGSEKNG"
     gene            29697..30092
                     /locus_tag="J8S10_001187"
     CDS             29697..30092
                     /locus_tag="J8S10_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HAZ9629777.1"
                     /translation="MGNLKYESNAEKIIENFKNMTVIAQKEGISFVNDSMNKVVSLAK
                     PLTPVKSGNLRRGYRVVKARKLSSGRIVGEVINNEHYFKYVEEGHRTKNGGFVKGKFM
                     LTRATNLANMSYIPRRFKQMAIKIVKKGK"
     gene            30094..30471
                     /locus_tag="J8S10_001188"
     CDS             30094..30471
                     /locus_tag="J8S10_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629778.1"
                     /translation="MKDEIIAAISSKLKEIYPDGTIYLDSVMQSTKDFYFVLSVMESG
                     TENVGIDIQNVSFLIDIALIDNNPNRNLINELVSRCGTFFNTITIDEQILFPKAYLPD
                     EADGVQHIRFTLEFPQYIEWSER"
     gene            30472..31080
                     /locus_tag="J8S10_001189"
     CDS             30472..31080
                     /locus_tag="J8S10_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAZ9629779.1"
                     /translation="MGEKRSKTGIISVEKPTWFPLEDETGNFPVYGTALPMGTAVSIK
                     PTANYETTQDYGDSVVQDQFTAFGGAEVELEANGYTHKVLSTITGGKIVKGGALRSGE
                     DIAQDGAFAYRRKKSNGKYRYTVFYKGQFALDSDETSTIEGSKVSFTHPTWKGSFVDV
                     PGLGYMYSVDEDDEGVDKAMIGNWFTKVAIPIEEAELSGGTE"
     gene            31080..31421
                     /locus_tag="J8S10_001190"
     CDS             31080..31421
                     /locus_tag="J8S10_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629780.1"
                     /translation="MSKYQTTIKLTKKDEEGKYEQVQFKSAEFLPGTVVEDAAGVMEE
                     MQTATDKQSVKKALSRAYSFIADTLFEGQFTGEDYCKGIDAREIASLTGKLLKSVTAG
                     FDETYTETKKK"
     gene            31663..34452
                     /locus_tag="J8S10_001191"
     CDS             31663..34452
                     /locus_tag="J8S10_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HAZ9629781.1"
                     /translation="MILDESGFTAGMNNAVKKLNSFDETIERKSRNSGSSLGSIWKIF
                     AGSFLASGVTRIVGAGFDLIKGSISGAVDRVDTMNNALRNFQNMGFSNSEIMKNIGKN
                     GLLSQGIQGLPTALNDAISHVQLLASSTGDLTRSTQIFKALNDGILGFGGSTDQVNEA
                     VIQLSQSFSNGKVDAQTWNSMINAQLGPTLSAIAKKMGITMGDLKEGLSQGKISVEEF
                     QNQLIEMDTKGGGGLKSLSQIAKDSTKGIKTSIQNAKTAVTRGVGEVIEGLNKALVDS
                     DLGGFKGIIDKVGSSMESFLKVIAANIPTAVSFLSNLFNEIQKFGSALKFMMPFLVPA
                     ATAFGAFMFQLKGIPAIIKSFNNFKNAIIGVGNSLKIMGAIAAANPFVLIIGAVVGAI
                     AVFGYFMATNEELRNKVISIWNDVKDSVIGVLKNIKDWGIDTWNSAKEMASNAVEGVK
                     DAWSGTKEWFSNTWKGIKDGATGLFDKTVETSRNAVDSVKNAWSNMKKWFSDTWQSIK
                     DSAREKWNGIKGSIMSVAGPLITGIKNAFLHVTFYLETLWNNLVEIGKNVFEILKNVI
                     LAPVLFITSMISGGWEETKNNMIAVWNNIKESAINIWESIKNIFVSYFTNIYFAALNI
                     WTGFKLTLINIWNEVVNQAKSIWLNIKYFFINLWIDIKYFAIQKWIELKFSIIQTWID
                     LKYNAITTWNNIKQFFKDTWKNIKDTAYNTWISIKNTMINTWNNIKDSFWNIVTGIVN
                     SAENAWTNLKNGVSNAINRVKEIFNSLREVNLFEIGKNIIDGLINGVKEKWNALKDTI
                     KGIAGNIKNWIKGALDIHSPSRWMRDMVGKNIVQGIIVGIDKEQSKLDQTMTNLVKTP
                     SVQPVVNGISHLPITQTKQNISASETKEIHLHLNVYGDLPDSMVRKITTKIKTELTRQ
                     MKRDAGAVGGTLYAT"
     gene            34442..35182
                     /locus_tag="J8S10_001192"
     CDS             34442..35182
                     /locus_tag="J8S10_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAZ9629782.1"
                     /translation="MQLKRGQFFINQHYSSEFNVYIQNRPASVSASRVIELREREGND
                     SIIIDKGYYKNVTRKIECYYKAPSIDMVQEWEDRITEWLDMSSYSDFILYYDEQYIYQ
                     AVVIEGPEFKGTRKTGNIVPFEFTVSIRPFKENYNGRFTIRQTETFEIYNPEKYSSKP
                     LIKLSGSGDASFYINKDKYDLKSLDRELFIDSKLEEAYRKLDGNLEHQDQVTLFLDFP
                     FLYPGKNEIKWTKNIHSFEIMPRWWRKV"
     gene            35179..>37016
                     /locus_tag="J8S10_001193"
     CDS             35179..>37016
                     /locus_tag="J8S10_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629783.1"
                     /translation="MKPRIYSPTETDFSTNGLGILKDCTRCGIYEVANGKYELELDYP
                     LGTRFDEYFENDYQIKAKPNDQEEYHIFFIDDKDIDTFLNTVTIYAQSRTNRLGRRVV
                     TLVEVDSKTGQEAISIIETKMDKKSDIRLYSDITAVSSTIFEARNVLNCIAGEQGSLL
                     QYWGGEIKREPFKLSLLKRRGRNNVGTIRYGKDMSGLKVKLDWTGIKTRIIPYADPQS
                     EVGTTNRIYGSPVDSAYINNYPDVYTEHVQFTEEQGVKDIKSLNKIAKNYFKTINPGC
                     DKPKVSITVEFDKLTDSEEAKEFAKIRNYGLFDTFKIYHKKYNIYLESKVSGLQYDSL
                     SEKTLKLEAGDIQVAFYQQQAVTIQDKLKDYATNNYMSDFNDYVSSMITGQGSAGGYV
                     VLWPKEKPSNIFIMDNPDLEKAREVLRMNKNGIAFSKKGWRGPFNSAWTLDSIFNANF
                     IQTGLIKADIFQNSFNKTGDVLKLVNGLLQIWNNKKKIMELTKKGMEFWNSKGSIGTI
                     GTTDSVGNPFPGASTPTPIEDNSLVIRTNGDGKYILISPKVGKGLVLLGNGKAIYFGD
                     LDVQGKLTVKGKEIIPGQGGGPSGGGESTGGYPSELKTDAEKRAWR"
BASE COUNT        12678 a         5545 c         7497 g        11296 t
ORIGIN      
        1 tggttccgtg gtgtaggggt taacatgcct gcctgtcacg caggagatcg cgggttcgat
       61 tcccgtcgga accgtttggc tcggtagctc agttggtaga gcaatggatt gaagctccat
      121 gtgtcggcag ttcgattctg tcccgcgcca ttatgcgggt gtagtttagt ggtaaaacca
      181 cagccttcca agctgttgtc gcgagttcga ttctcgtcac ccgcttttag tttttatggg
      241 cctatagctc agctggttag agcgcacgcc tgataagcgt gaggtcgatg gttcgagtcc
      301 atttaggccc atttatttta ttggcccgtt ggtcaagcgg ttaagacacc gccctttcac
      361 ggcggtaaca cgggttcgaa tcccgtacgg gtcatggaag atactttttg agtatctttt
      421 tctttttatc tgaaagaatg attttaaaaa gcttagcaga gttatcttta tggatgattg
      481 tgctaagctt ttttggacag ttctaatgta aaatattttt atatttttta agcaaaaaaa
      541 tgaaaaaata cgagcagaaa actgttttat ctgctatact tggttcgttg caagttcccg
      601 aaaggatccg caggacggag atgccttgta accgaattta actaggggga atcattataa
      661 tggtagaaag acacttattt acatcagaat ctgtttctga aggacatcca gataaaattg
      721 ctgaccaaat cagtgatgca atcttggatg caattttaaa acaagatcca acagcacgag
      781 tagcgtgtga aacgtctgta acaactggtc ttgttttagt atttggagaa atatctacga
      841 cggcatatgt agatattcaa aaagtcgtac gggaaacaat aaaagaaatt ggttatacac
      901 gtgcaaaatt cggatttgat ggagatacag cagctgtatt ggttgcgatt gatgaacaat
      961 ctcctgatat tgctcaagga gttgatgaag cacttgagat ccgggatgaa gataaaaaag
     1021 acgtattaga tgagattggt gctggtgacc aaggtttaat gtttgggttt gctgtagatg
     1081 aaacaccaga attgatgcct ttaccaatcg ctttgagtca tcgtctggta cgacgcttgg
     1141 cagatttgcg taaatcaaat gaattaacgt atttacgtcc agatgcaaaa tctcaagtaa
     1201 cggttgaata tgatgatcaa ggacaaccgg aacgcgtaga tacaatcgtt atttcaacac
     1261 agcatgatga tgcagtagat aatgaaacaa ttcgtcatga tgtcatcgaa aaagtagtga
     1321 aggaagttat tccagctgaa ttattagatg atcaaacgaa atattatatc aatccgactg
     1381 gccgatttgt cattggtggt cctcaagggg atgccggatt aacaggaaga aaaatcattg
     1441 ttgatacgta tggcggttat gctcgtcatg gtggcggtgc tttttctggt aaagatgcga
     1501 caaaagttga ccgttctgcc agctatgctg cacgttatat tgctaaaaac attgttgcag
     1561 cagggcttgc tcgcaaagca gaagtacagc tagcttatgc gattggtgtt gctcaacctg
     1621 tttcgatctc aatcaatact ttcggtactg gaacggttcc ggaagaagaa ctgattgctg
     1681 cagtgagaga aaacttcgat cttcggccag caggaatcat cgagatgctt gatttgcgtc
     1741 gtccgattta caaacaaaca gctgcttacg gtcattttgg tcgtacagat gtagatttgc
     1801 cttgggaaca tacggacaaa gtagatgcgt tgaaagcaag tttagcaaaa taagttatat
     1861 tcagctggaa cgatcgccaa gtggtggttg ttccagcttt ttttatggca gttaacctct
     1921 tgaaaaagat agtaattatt tatctatttt tagatcctgt cataatgaaa gggaggaata
     1981 agatgaaaaa agaaacaaat gttactttgg tcacagtgag tattttcatt gcaacgttca
     2041 tgacggctat tgaaggtaca atcgtaacaa ccgctatgcc aacgattgtc ggttcattac
     2101 atggaatgga aatcatgaac tgggtatttt cgatttattt gctgacaaac gctatgctta
     2161 ctccgattta cggaaaactt gcggataaag tgggacggaa accaatcttt atttttggga
     2221 cattattgtt tattatcggt tcgttatttt gcggtttatc tcaaagcatg attgggttga
     2281 ttgctgctcg tgcgattcaa gggatgggtg ctggggcaat gatgccagta gctttgacga
     2341 tcatcggcga tctttattct attgaaaagc gagcaaaagt tttaggtttg aatagttcag
     2401 cctgggggat tgccagtgtt tttggaccgc ttgcgggagg attcatcgtt gaaacgatca
     2461 gctggcactg gatctttttt atcaatgtgc cgatcggaat tctattaatt attttgattt
     2521 ggctatattt aaatgaacca aaaatcatac atgagtctaa accaatggat atttttggta
     2581 gttttagttt gatggccatg cttgtctcat tgctgttagg gttccaatta ttaggagacg
     2641 aaggaatgag tccgcttgtt tctgctttgc tgctaggtag tatcgtaatg ttaggtattt
     2701 ttgtttttgc cgaaaaaaga gctaaagatc ctgtcatcat gatgcattta ttcaaaaatc
     2761 cactatttgt tgtggtcaac ttggctgcag cattggctag tggttttttg atgggaatcg
     2821 atgtttatat ccctatgtgg atgcaaggtg tattagggct gaatgcagca attggtgggc
     2881 tggtattagc accattatca ctagtctgga tggtcggttc tttccttgca agcaagtgga
     2941 tgactcaaat gaaaactcat tgggtcttga gaattggact actaatcgca gctattgggg
     3001 gcgcttggtt gtatcttatg cctttcagaa gtaactattt atggtttttt gctatatcaa
     3061 cggtcatcgg tataggctta ggtgtgacca tgactacctc gactgtcagt gcacaaaata
     3121 gtgtatctcg tgaccagctt ggtgtagcaa cttcttttaa tacgttagtt cgaacaattg
     3181 gtcaaacagt catggtttct atttttggtt tattgataaa tggggtaact aaacgagaac
     3241 ttgcagcagc aaatttaaca aatgatgcag atatcatgaa taaactggtg aatccacaaa
     3301 cggctaaata tattgatgcg gatattttgt taccattaag aaaaattctt tatgatgggt
     3361 tacattccgt ttatctagtt ggcttgttac tcgtgatcat tgctttggtc ttaacgcttt
     3421 tcgttcatga aaaaagtggt aaaataaaac agtagtttcg gttaagatat gtacgtagcc
     3481 gaatcattca aatttaaagt tattcaaaaa taacttctta ctaaggaagg cgaaaatatg
     3541 gcatttattc aagcaaatat ttattcgaat gtgttagaaa tggaagtcaa tctaaatgtg
     3601 atactaccgc aaacaacaaa aaaggtgatt ggcaccagtt cagagcaaga gacaacggat
     3661 atacctgttt tatatttact tcatggaatg ggtggcaatc atagtgtatg ggaaagacgt
     3721 acgtcgattg aacgttatgt agcaaactac ggattagctg tcatcatgcc atctactgat
     3781 cttggctggt acacagatac agtttatgac atgaagtatt ggacattcat tgcagaagag
     3841 ctacctgaga tttgtcatga attattcccg caattaacaa gaaaaagaga aaaaacatat
     3901 gccgctggat tatcgatggg cggatatggc gcgttaaaac taggccttgc aaaatcagaa
     3961 aatttcgcag cagtaatctc tctttcaggc gctgtttctg taggaaatcg aatggatgat
     4021 cttttgatgg ttcgtaaagc atctttttgg gaagggatct ttggaccatt ggatcaaatc
     4081 gaaggttcaa aaaatgatcc gcaatactta ttgaaagaac tagtaaaaag cggaaaacca
     4141 gttccaagat tttatatggc ttgtggggaa tctgattttc tttatcaggc aaatcaggaa
     4201 atggtatctg ctatgcagga acaaggcttg gcggtcacct ttgaacaagg acctggcgat
     4261 cataactgga tcttctggga ccaatggatt caacgtgcat tggcgtggct aatggaagaa
     4321 aaataaaaaa agagtcttaa aaagatagct cctatagaga tcacaaacat agtgatctct
     4381 ataggagctt ttttactgct cgttttctct tcttttattt tgttggcata agccttcaat
     4441 ataggtttgt gcactcgtta gaaagagtgc tttttcattc aattctgcat gggactgcat
     4501 actttcttta aatccctcta attgattttc aactacataa ttacgcataa atagaactgt
     4561 ttctttcaaa aattcatttc cgtccataat tttttgtcga agctgctgtt catgctgctg
     4621 atccattaac tgtccaatca ataaattgtg gagagaggca atggcctgat gactttgggt
     4681 gactgaaaat ccttcacgaa caagtaattg gatcatttgc tccaaatgtt ctaatcgact
     4741 cggaaaagcg ggcacagtat tgatttctaa ttctgcccca caagggaaac gtgtataaag
     4801 gtcatagtaa ttttccatat actgcagcaa ctgttcattc caaggcaaag ttggatctgg
     4861 aagcgctaat tcttcttcca ttgtttcagc cattttttgc aagagctgtt gtttgttttt
     4921 gaaataccaa tataaagcag gtgcttgaac atgaattctg tttgcgatgt ttcgcatgga
     4981 aagctgcgaa agagcttgtg tttcagccag gatatcaaag gcggcctgaa tgatgattgc
     5041 ttgagaaagc tttatttcca ttttatcaac ctcgtgtatt gcattatctt tttaaacatg
     5101 gtaaattgtt agtcggtcta attttacagt gttaaattag tcctgtcaat ttaaacaaag
     5161 gggtgtaatc aacgaatgaa attaatctta cgacatgcga aaaaatataa agtatctgtt
     5221 tttatttcct tgctgtccgt agcagtcatg gttgcagcag cattatggca acctaagtta
     5281 ctacagcaag tattggaagc tattattaca gaagataatg atgaaatgaa aacaattggt
     5341 atttacctga tcagtctggc tttgctagga ttagccgcag gtgtaacgaa cacgattttc
     5401 tctgcaaaag tagctcaagg cgtaagtgca gatatccgag aagaagcatt tcgaaagatc
     5461 cagacatttt catttggaaa tatcgaacag ttctctgctg gaaatcttgt tgttcgtcta
     5521 acaaatgata tcacgcaaat ccaaaattta gtgatgattt ctttgcaatc actttttcga
     5581 attccattct tatttattgg tgccttcatt ttagctatga tcacgatgcc gcaattatgg
     5641 tggatcatcg tagcgcttat cgttacggta tttctgatta cggcactttc atttacaagg
     5701 atgggcaagc acttcatgat cattcaaaaa ctgattgatc gtgtgaatag cattgcaaaa
     5761 gaaaacttac tagggattcg tgtagtgaaa tcttttgtac aagaagaaaa ccaattgaag
     5821 tcattcagca aagtaagtga ggacttaaca aaacacaaca tcatagtcgg tacattattt
     5881 tctgtgatga tcccgtcctt catgctggct gccaatttgg ctgtggttgg ggcgatcttt
     5941 tttgtgagcg atcttgttaa agatgatcct acgttaattg gtggaattgc ttcattcatg
     6001 aactacttga tgcagattat gatggcaatc attattggcg gaatgatgat gatgatgact
     6061 tcaagagcag ccgtatcgct gaagcggatt gcggaaattt tagatgctga accagatctt
     6121 acttatttag acgttccaga acaagagttg acgggttctg tcacttttga ccatgtttct
     6181 tttcgttatc ctggtgagga tacagatacg cttaaagata tcagcttttc tatcaaacct
     6241 ggagaaatgg ttggtatcgt cggggcgact ggtgccggga agtcaacact agcacaattg
     6301 atccctcgtc tatttgatcc gacagaaggc aaagttgaag taggtggtgt agatcttcgt
     6361 caagtaaatg aaaagagttt aagacaaacg gtttcctttg ttttgcaaaa agcaatttta
     6421 ttctcaggaa cgattgctca aaacttgcgc caagggaaaa agaatgcaac agaaaaagag
     6481 atggaacatg cttcttctat tgctcaagca aaagaattca tcgaaaagtt atctgatcgt
     6541 tacgaagcac caatagaaga acgtagcagt aacttttctg gtggtcaaaa gcaacgttta
     6601 tccattactc gtggcgttat cggtaatcca aagatcttga tcctagatga cagtacgagt
     6661 gcactggatg ctcgctctga aaagctggtc cgagaagcac tcgatcgaga tttgaaggga
     6721 acaacgacga ttgtcatcgc acaaaaaatt gcttctgttg tcaaagcaga ccgcatctta
     6781 gtattggatg aaggcagatt agtcggcgaa ggaacccatg aggaattggt agctggaaac
     6841 cgtgtctatc aggaaatctt tgaaactcaa aaaggaacgg aggagtaagt atgactgatc
     6901 taataaaagc aagtaaattt ttctatcact atttgaagcg gtacaaactc tcctttttct
     6961 ttatctttat cacagtgatc attgctacct atctacaagt aaaggcacct caatacatcg
     7021 gggaagcttt tcaagaatta gctaattacg taggaggctt gatgcaaggc gtagacgata
     7081 aaagcaaatt tgtttctgta atatggaaac tcttgctgtt ttatgtacta gctagtgcag
     7141 ccaactttat ctatagtatt ttgttcacac aagtagtagg gaagtcaacg aaccgaatgc
     7201 gtatcggtct attcaacaaa ttggaaaaat tgacgatccg tttctttgat tctcatcaag
     7261 acggtgaaat tttaagtcgt tttaccagtg acttagataa tattcaaaat agtttgaacc
     7321 aagctttgct tcaagtcatc acgaatgctg ttttacttgt cgggatcttg atcatgatgt
     7381 tccgccaaaa tgtagagtta gcttgggcta caattgcttc cactccagta gccgttttga
     7441 tagctgtctt gattatccgc aaagcacgga aatatgtgga tcttcagcaa gatgaagtgg
     7501 ggaaactaaa tggttatatg gatgaaaaaa tcagcggaca acgtgtcatc atcacaaatg
     7561 gcttacaaga agaaacgatt gaaggattct tagagcataa tcaaagtgtt cgcgaagcaa
     7621 ccttcaaagg acaagcttat tctggtctac tatttccgat gatgcaagga atgtcactgg
     7681 tcaatacagc gatagttatc tttttcggcg gctggttagc attaaatggt gatttggaac
     7741 gttcggtggc attaggctta gttgtgacat tcgtccagta ttcacaacaa tattaccaac
     7801 cactgatgca gatttcatct ggatacagca tgatccaatt agcgattaca ggggcaagac
     7861 gattgaatga aatatttgat gaaaaagatg aagtcaaacc agaaaacggt aaagcatttg
     7921 atggtgttga aaaaggtctt gcgttgcagc acgtagattt tggttattct ccagaaaaac
     7981 tagtcttgaa agatgtctcg atcaatgtgg acaaaggaga aatggttgct cttgttggtc
     8041 caacaggatc ggggaaaacg acgatcatga atctgctaaa ccgtttttac gatgtcaatg
     8101 atggttcagt agtcatcgat ggaatagata tccgagatta tgatcttgat gcattacgta
     8161 gacatgtagg aatcgttttg caagaatctg tattgttctc cggaacgatc aaagacaata
     8221 tcacattcgg caaaccggac gcttcagatg aagaagtcat caatgcagca aaacaagcga
     8281 atattcatga cttcatcatg acgttagaaa aaggttatga tacagagata tccgaagaaa
     8341 ataacttatt cagtacaggt caaaagcagt tgatcagtat tgctcgaacg atcatcacaa
     8401 atccatcttt attgattttg gatgaagcaa caagtaatgt agacacggta acagaagcaa
     8461 ggatccaaaa agcaatggat gaagcaatca aaggaagaac cagctttgtg attgctcacc
     8521 ggctgaaaac aatcttgaat gcagatagaa tcgttgtctt gcgtgatggg gaagtcattg
     8581 aagaaggcag tcatcatgag ttattagcag aaaatggatt ttatgcggaa ctttatcata
     8641 atcaatttgt atttgaaagt taaattaaaa gaacctcgtt ataacggggt tctttttata
     8701 tattttatgt tgtttgtttt tataaggggc agaaaagggg caatttaaat ttctattttt
     8761 cctagttttt ctactagttg attttgcata tttttagttg tatgagtata aatctttaat
     8821 gttgtttttg aatcttcatg tcctacacga tccataatgg cttttaatgg gattcctaat
     8881 tctgtaagta gagaaatgtg ggaatgcctt aacatgtgag aagaaacttt tttatctagg
     8941 tttaattctt tggatactgc tcttaaagat tgattatatg cttgaataga tatcgggtta
     9001 ccatttttag agatgaaaat gtatttatct ttattattct taattaattt gttttcttca
     9061 attaattgat ctatgatttc tttagcatta cttgataatt caatggttct ataagaacct
     9121 gtatttttag ttgttgtttt aatttttaac tcgtaatcat aagtaccaga aaccgtaatt
     9181 ttattaccat cataatcaga ttcagtcaaa gatatcaatt caccataacg tagtccagtt
     9241 aaaaacaaaa atttagtaat taaagaataa cgtgactgtt gatgtgaact tttttgttta
     9301 ctagcaatca tttgaacttc ttcttttgat aaataaccat ctttttcttt ttttatttct
     9361 tcgtttgtct taggttttct tgctaaagaa accccattta cgggattata ttttaatcca
     9421 tatcgacggt tggcgaattt aaaaatcatt cctgtaaaag tttttaaatg tattacataa
     9481 ttatatgata aatttttttc aaaatagtag taatctagca tatcttgtat aagattacta
     9541 ttaacgtttt ttacaagtac atcatctttt atatattttg aaattaatga tagataaacc
     9601 tgagttgttc gataggaact ttcttttaca gttggcttgt atttttcatc ccatttagtt
     9661 tttaattctc caaaagttag tggtaattct tcatttcgtt ttattttttc tgcgattttt
     9721 tcattcaaaa gtaagttagc ttgattccaa gcttggcgtg aattgctaga taaagtaacg
     9781 gacacttttc tctttttttc agttaaggga tccgtataac gttcggtgta cttaaatttt
     9841 ttgtcattta ttttttctaa ccacattatt tctattcctt tcgaatatac gttcctatta
     9901 attgttaaaa gaaaaagccc gaaggctttt tatatattta atcttttgac aattctaaag
     9961 atcgtctata ttgttcagct ttagctaatt ttgtaaatgt tactgttcca ttataatttt
    10021 ctaaaacaac tttctctatt tcgtctagtg aaactttgaa aaattctttt ctttgattaa
    10081 ttttattaac ttcttgtttt ctaaaatgat tatgcaattt agtttccaaa gacggagcgt
    10141 cctctgaaaa aatcatcgca tgaacgtcaa attcaaatgg aaccgatgca ctactcaatt
    10201 cttttattct atccataggt tctaatcttc tagtcatacc aattttatat atgtcttcac
    10261 caaaagaccc aatattacta attacataca cataaccggc tctagtattt aattctcttt
    10321 gtaatacatt ttcacgtata acttctaatt cttttaattt ttcttccagt tcttgaattt
    10381 tatttgcata taattctttt tccacatctg cattagcttt ttgcatatat gcgattaatt
    10441 tggaaatttc agaattgaat tgacgttgtt ctttatcaat acgtttcttt tcacgatcaa
    10501 tttctctacg aactttttcc tcttctatca tctgttcttt tattgctttt tgttgttctt
    10561 tttcttcggt aattttcact aaataagagt aatgaagttc tagttcttga agtttaaact
    10621 ctaaaagacc cttccttaat tcagcattgt cattcttgaa taaattatta attttatcaa
    10681 atatttttat gattttttcc ctagtcgagt ctatattaga aatagttagt ttattgagta
    10741 atcctttcac ttctgaatca aatggaatga gcattttttt ctttaaatta tttttctctc
    10801 gtttatttaa aataagaggg acagaaacag catcgtcaat aatatattcc ttttctttta
    10861 attttaacaa agaaagctta ttttttattt cagaagatga agtttcttct atatttgaaa
    10921 cgataagtga agaatagaca ttttttaatg tttcatcata cttttgattt atttcatcat
    10981 ttaaatcttc tttctctttt tttaataaaa taatatcatt ttttaacata gtaatttgtt
    11041 tatttaaatc tgatagtgtt tcttccttac ttaatataaa tctttctcta tcatgtaatt
    11101 tatttagttt ttcatcattt ttttgttcta attcataagc ttcttttttt attgtgttag
    11161 ctttcgacag tttagtgatt cctataatta ataaaataag tccaatcaat aataacattc
    11221 aaaactcctc atttctttga tataattatt gtagagttta ctcagaaatg aggaaagagt
    11281 ccatgtgaaa gcatgggctt ttttattttt aatgttgtaa tactaaatgt tcaagattat
    11341 gaggaagccc taaatattca ataatttgga actgactcat atcagataaa tcttgttcat
    11401 ctattgttct agttaacatt tcaattgcaa acatattagc ttcagcttct ataccataaa
    11461 tcatacaact aaggttgttt gctctaaaag ctgctgtgca aataccttta tggagtctaa
    11521 cgtgggctat ttcatgccat aatacaaatc ttttcataga aggtgatagg ttttgattaa
    11581 ttaatatcac ataacatctt ttattgtgta tcgtttgtcc taatgtttta ttccctaaat
    11641 cagtttcaat taaatctata tcagaatatt tgattatttt atatggatta atcgcatcag
    11701 atccaaactc tacaaataat ttttctattt cttctaatat ccagtatttg tttaaatgca
    11761 taccaaagcc cacctattga cgatattttt taggagtgaa ttttttcttt gctttaactt
    11821 tggttaaggc aagtgcaagt tgaatggcat cgtataattt ttccttatct tcatcgtcta
    11881 aaggttcacc ataataattt gtttcagcat ctgaattcaa gccttcaagt aatttttcag
    11941 cttgtaaagc aatatcttgt ttatcttttt ctgttaaatc ataataatgg cgtttatcag
    12001 tacgtcctaa aagataatca gttgatacat taaagtaatc tgcaactttt tgtattttat
    12061 ctccagatgg agtactttta ttccatctag acatgcttcc atttccgaaa tttaactttc
    12121 tttcaagttc tgccaacgtc attgaacgtt cttttaataa gatttttata cggtctaata
    12181 gcataggata tgcattcctt tcaaaatacc gacaaaaaaa gtatttttct gcaaattatc
    12241 tatttacaaa tagagaattt gcagttatac tagttttgta agcaagatat ttacggcata
    12301 caaagactaa aagcaataaa ctaatagtct ccccagacat cagtaagctc gctttttgtg
    12361 cgctgtattt tgtatgctta cataatagca tatttgcagt ttttgtcaaa cttattagac
    12421 aaaaatatta gaaaatattc gataaggggg tatgaagcat gactttaaaa cagcaagtat
    12481 taattgcttt agtaaagaaa ggttggagtc aaagagagtt agctcgacga atgggtatat
    12541 caattactta tttacgagat atcttcatcg aaaaaagaaa acctaaggaa cgtttaaaac
    12601 aaatcgaaga acttttggat atcaagttag aagtagattc taatgatcag ccatcagaac
    12661 aggaggcgta aaaatggtac aacgtttgag caaagcggag tttaaagaga aatataagta
    12721 ttctgaaagt acttatcaaa gaagaatgaa ggaatttaaa aaatcacgtt ttagtgaggg
    12781 gtataacgca gttacttcca aagaaataac aattgatgtc gatttatatg aacagtttag
    12841 aacatggcgt tctaaaaatc gatttagagt tagagctgtt tgttaatagc taaaaaatct
    12901 aaattcacca cttctgaaaa gaggagttgc tgctctcctt tcaagtttgc caaagtccac
    12961 gttttttcat tttggcaact cctcttcttg gaggtggtga cggcgagaga cgaaggaggg
    13021 atgacatgaa ggaagaatca aaaataggga ttttgaatga gaacaattac acaagattaa
    13081 ttattgaaac agaagaaggg aaaaaagtag cagaagttac attgaccgat gcaactcctg
    13141 ctgacggtta tcgtattcga ttaactccta aatatgatta accttttggt gggtgtggat
    13201 cgtttccgtg actatcacgg ctttgaattt ttccatctct gccatgaata aatagctcag
    13261 atccttgatt tttagaaatc tctctagcga tttttactgc ttctgatttt gtattagtat
    13321 gtgcagtcgc tttagaattt ccagcacctt tgacattcca accaccattg gaattaggta
    13381 caacatgttg attttttccc atagttttca cctccatttc tatagaaata ttttatcaaa
    13441 tagaaatgga gaaattcaat aaacgaaagg agaagtgata tggcatatac cttgcaacaa
    13501 gaacatcaaa ttctcggttt gattaaacaa cgcaggaaac aattacaaga tgaccgtgca
    13561 gcgcttagaa aagccgatga gctatcagat aggcaagctg aactaattgc ttctgaactt
    13621 gaggatttga gaatgctaga aataaaaaat agggagatta gattatgaag aagacagaca
    13681 cactttttat aggattcatt ttggggttat tagtgattgt agcgcaccaa agtattatcg
    13741 ggggaagctt gttcgcagca ttgatggttt taatcaatct gcttgattca aaagaaagga
    13801 gcaactatgg cacgagaaga agcgctaaaa atcggtaaag tgattgctga taatcggtgg
    13861 ggaaatagcc gccctattat tttaagcaag caacatatcg aaaagcaaaa agcatggcaa
    13921 caaataaaaa agtgactctg ccagccagca aagagtcaca tacaaattta taaaactagg
    13981 agaattatat cacatgaata agaaaattga aaatcttatc gaagaattga aacgtgaatg
    14041 ccaaaagcaa ggtgtttcta ttatttgtac agcccaaaaa gaaggggaac ttaaaagtct
    14101 cgtttatggt gagacaacag aaattttact ttgtcttgct atgcaagaag aacatttaga
    14161 tgaaaatctc ccattgtcag cacatattat gcgtagaatt gctgtggatg cttacgaaca
    14221 agcgaaaaat gaagaagaaa atcaaccttc aaatcatact tttgttatta ataacaagga
    14281 agatttagct gatgtgatga ctcgtattct caagggggaa tttcaatgat gaatgaaaaa
    14341 acaattgatc tactcattat tttatttttc acgttagtga ttgtagcgaa aagttatgta
    14401 atctttggct tgttattcgc aattaccatg cttgtgcttt gcgtgttagc aagcagaaaa
    14461 gaggttaaac atgaacgagt tagcaaatct tgacaactat ttaactgatc ctgattatgc
    14521 taaaccacca tatgaagcac caattgatga ggaggatgaa gatgagtaaa tctaccttag
    14581 aaatgagcca tcaagaatgg cttgaagacc gtaagaaagg catcggaggt tcggatgttg
    14641 gaacaatttt aggattgaat aaatggaaat ctccttatca actatggcta gaaaaaacag
    14701 gacaagtagt acttgaagaa tcaggaagtg agcccgctta ttggggtaat gttttagaag
    14761 aagtggttgc taaagagttt caggaacgta caggcaaaaa agtacgcaga agaaaccaag
    14821 tatttgaaca tccattacat ccatttttaa gagcaaatat tgatcgggaa gtagtgggag
    14881 aaaatgccat tctggaatgc aaaacagcca atcaatttct cggtaaagaa tgggaaggcg
    14941 aagaggtacc gcttagctat ctctgtcaag ttcaacatta catgaacgtt ctaaacaaag
    15001 actattgtta catcgctgtc ttaatcggtg gtcaaaaatt tatctggaag cggattgaac
    15061 gagatcaaga gctgatcgat acaatcactg aacaattagt agagttttgg gaaacaaacg
    15121 ttcttggagg tatcgagcca attattgatg gtagtcaagc gacagctgat ttcttgaaag
    15181 agaagtatgc agatgttgaa gacgttcaaa cgacgttacc aattcatttc gatgaactag
    15241 ttgaacagaa aaacgaactc aaacggacta agaaagaaat tgaatcagct atccgtcaag
    15301 tagacaacga gattatcagc gagctaggta aacgtgaagc cagtatcggt atcactcaaa
    15361 aaaacatcat cagttggaaa tttgtccgta cgagacgtat gaactcgaag aaactagcag
    15421 agaaatatcc agatgtcgca aatgatgaag agatttataa cgttactgaa tcaagaaggc
    15481 taaccgaaag ggagatcaaa taatatggca acaaatgaat cgttaaaaaa tcaattggca
    15541 gcaaagccac agaaacaagt tgcaccaggt caattaggac ttaaagcttt gatgaataca
    15601 ccaacaatga gaaagaagtt cgaagaggtg cttcatgaca atgctaatgc ttttatgtcg
    15661 aatgttatga ctcttgtatc taatgacagt tatcttgcag atagtgaacc gatgtctatc
    15721 atgagtggtg cgttaactgc tgcaacatta aatcttgggc tagataagaa tttaggttat
    15781 gcatatttag ttccattcaa tagtaaaaac aagcaaacag gaaaatggga aaagaaagct
    15841 caattcatgc ttggctataa aggatatatc caattagccc aacgatcagg taaatacaaa
    15901 gcattaaatg tgatcgaagt ttacgaagga gaactaaaaa gctggaaccg actgacagaa
    15961 gagtttgagt ttgatccaaa tggtagaacg tctgatgaag tcattggata tgttggctat
    16021 ttcgagttac tgaatggatt caaaaaaact gtctattgga ccaaacaaga aatcgaagct
    16081 catcggattg ctaacaataa agatcgcgat aagacaaagt taagtggtgt gtgggcatct
    16141 gattacaatg caatggcacg aaaaactgtt ttgagaaatc ttctttctaa atggggaatc
    16201 ttgtccatcg aaatgcaaga agccaccaca tcggatgaga gagtccaaag ggttcaagaa
    16261 gacggcagca ttattgctga aacagaagtt gaagaagata ttcctgaaag aaaagaagca
    16321 gaggttatat ctgaagaaaa tgaagatgta caaactggat tatttgatgc atctaatccg
    16381 ccgttaaaca aataatgagg gagctttctc ccttgctttt ctagaggaga aatacgaatg
    16441 aacacaggat atgtcaaatt acatcgaaaa gtgatgaatt cattcgtttg gaccaatcct
    16501 tatatgtata aattatggaa cttgtgtttg atgaaagcga gtcatgagaa tcgcaagata
    16561 ctttttaatg gaaaagagat acaagtgaac agcggagaat tcgtcacagg gcgcgatgct
    16621 atcacatctg agatgaacga aggcgtgaaa cgtgaacatc aagtgaacag cggttctgta
    16681 tggagatggc taaaacaatt tgaaaaaaac ggaatgttga acatcaaatc aactacgaaa
    16741 tacagcgtta tatcaataaa aaactggtct ttgtaccaaa gcagtgaaca acaaatgaac
    16801 atcaaacgca caacaagtga acaacaagtg cacacaaaca agaatgaaaa gaattataag
    16861 aatgaaaaga ataataaaac atcatcgtcg caaccacgca aaaagcgtgt ttacgacacc
    16921 gactcagttt actacattct cgcggaggag ttattcaaac agatttgtca gaatcaggaa
    16981 atcaaaaagc cgaatctgca aagttgggca gatgacattc ggaaaatgat cgagatcgac
    17041 aagcggaccg aaaaccaggt acggggaatg attgaatgga gtcagcacaa tgtgttttgg
    17101 gcatcgaata ttttatctgc taaaaaattg cgagaaaaat acgacacaat ggcagcgcaa
    17161 gcaaatcgtg attataaaac aaaacaaact aaaacgcttg aatacgagaa atttagcaca
    17221 gatgagttgc ctatttgaga ggaggcgtag gcatggaaac tgttggggaa atcatggaaa
    17281 agctgataca gaaagtgctt gtccaacgtg gcgaatgtcc tgaatgcgga cagcctttgt
    17341 atggatggcg tacgaagaac cctgatggct cagaacgttg taagccaacc tgtatgcaat
    17401 gtgggtataa agcattgcga gttcaggaag acttacaaac agaacgaatt tacaacgaga
    17461 gcctgaaagc aagagcaatc aattttttca aaggtggttc tgttgtgcct aatcaagcgt
    17521 tgtttgattg cacattgcag aattatcaaa ttgtcgatca agaaacaaga caagcggttg
    17581 aagtaaccaa acgctttgtt aattcagtct tgttaggaaa tccaagtcac cttgttttaa
    17641 ctggaaaaca aggaacaggt aaaagtcacc tagcgatggc agcggcttgg gaagtcttga
    17701 agcgatcaaa ctacgataaa aaaatcttat ttatcgggtt acaggaaatg ctggatcaaa
    17761 tcaaattttc gtacaacaat cctgaactca gaaaaacgat tgagggatcg ttgattgcag
    17821 atatcaaaac agcggattta gtcatcattg atgatatcgg ttcagaacta ggaaaagatg
    17881 catcagatag tcgagcgttt ggcataaaca cgctaaattc gttcttggat gcacgacaga
    17941 acctagcaac gattatcaca acgaacttgc ttggtgaaga actgaaaaaa gcttacggta
    18001 cgagaacaat atcaagaatg tttgtcaact ctgatggatt tacgatggta ttttctcaaa
    18061 cagcagacaa gcgcataaaa ccagtcaaag gagcgatcgc atgaatttga ctaaacaaga
    18121 aaaaagaatc tgtcgtcaga taatgttgca aattataggt gatcgtgaca tggacgaatt
    18181 atctcaacaa gagagtcgaa tggttcggaa gataagtaag ctaattattt atcgggatac
    18241 agaaagattt ctcactgttt taggtaacgt ctacgagaat ccagagttat tggaggtaga
    18301 gtaattgcca aaaatattag atgcatgttg cggtagtaga ttgttctggt ttgataagaa
    18361 caattctgac gtaacattta tggattgtcg tcagcagtat gaagaattat caacaggtca
    18421 tgtgatcaat gttgatccag atgtggtcgc agactttcgc gatatgcctt ttgaagatga
    18481 tgtgttcgat atggttgtat ttgacccgcc acacttaaga catgtcggcg aaaactcatg
    18541 gcttgccaaa aaatatggaa aattagacga actttggcca gaagacatca ggcaaggttt
    18601 tgcagagtgt atgcgagttt tacgaccttc aggaacatta atttttaagt ggaacgagga
    18661 acagatacca ctttctgatg tgttagaggc tattggagaa cagccattgt ttggtaataa
    18721 acgaagcaaa acacattggc ttgtgtttat gaaaaaattc agctaacgga ggaaacaaag
    18781 gaggaaaagt aatgaagatt gtattaaata aatgttttgg tggctttggg ttgagccatg
    18841 aagcaaaaat ggaaattttt aaaagaaaaa atattgaagt attcccatac atcaataact
    18901 ttagctatga ctcagatgat gaatacacga gatacacagg ccaaaagcta ggttcgatgg
    18961 attttatcta ctatttcaaa aaagacccga aaatcgacaa agttacagga atttatagcg
    19021 aaattgaccg actgtacgga attgctgatg attccagttt ttcaagtgat tcaaacagag
    19081 gtgataagga cctcgttgct gttgtcgaaa aactaggaag tgaggccagt ggaccatatg
    19141 caagtcttaa agtcgttgat atacccgatg gggctgagtg ggaaataagt gattatgacg
    19201 gcgttgaaac tgcacattat ggttttcaaa caggtagtat ttagtccact aatgacaact
    19261 aaagaggagg cagaaggatg agtgaagatg aatactttga acagtagtct attaacgaca
    19321 gagattttta actggaaagg ggtgtagtca tggacgcatc ggaagtagta aataaaatta
    19381 atagtctcaa agaggttttc ggagacgtcg aagtagtgat aaacgcacaa ggctatgaca
    19441 acgaattttt taagcagatt accgacatta gcattcagca aggaatggaa gacgaagacg
    19501 gaaactttat cgatgaagta gccattttag tgacttgcga gtaagtaatt gacagctaaa
    19561 gaggaggaag cggaatgaaa ctaaaagacg gattttactc cagcggccac ggcatcggcg
    19621 gtttaatgct agatatgccg acaaagaatc ctaaaacacg taagaaacca aaattcaaag
    19681 tcggtgacat ggttcgctgc gaagcagaag gattcatcta tccatttcgt ggatatgtag
    19741 aacacgtcta taatcactca gcaatcattc gcattgaaaa cacgatggaa tgtgataagt
    19801 ggttagcgaa aagcaaagag aatttagcag tggtgagatt ggtggacatg gaagttataa
    19861 aatcttaatt ttgctttttt acaactatcc tacaacaatg agcgttattc cacaactgga
    19921 aggagaagag gcaattgtga acattttaga gaatatagat attaagcaaa caaggaaaaa
    19981 tgctagacga ttactaaaaa gatacagaaa tttagaacgt ttggtcggac cagtgaaaat
    20041 agacttttcc gtgatgactg ttaccaaaaa tttgaaattc acaattgaca gtcaaaacga
    20101 agaaatcatt gaagcgataa gtactcgaga ttcggttatc gaagcattaa cacggctaag
    20161 tagaatccat ttccaggtac tttattatag ttattgtttt cctaataaga tgtcaatgta
    20221 tcaaatagga gaaaaattag gatattccga tagaactatc gagagaatga aggcagtagc
    20281 tttggttgaa tttgctgagg cgtataaatc aggagaactc atttcacgta caaaataaaa
    20341 aaagtcggat tcctccgact atgaataata tttccgacat aagtattata tcataattgg
    20401 gggaatcaga ggatggtact tttcgatgta aagaaatatg agacaccaag cgcgaaagat
    20461 gttgatatgg aacgcacaaa acataatgtc gctgtgtttc tttcagcata tctatcagct
    20521 agatgtagag tagggcaaca tcgagaacca aaagtgacag catcttattc cttggttcca
    20581 ccttctacag ctgatcatat atttgaagca gaaagaatgc tgatcgataa agaagaagca
    20641 caggaagaat ttgagtatct gcataaattg tttgttcgag gctattcagc gatacagcat
    20701 ccgcataagc ctgatgtgac tgaaaggcgc aagaagatat tctatgatcg ttatatcaat
    20761 ggtctgccca tttatgtaac tgctcaaagg aataatacta gcgaagaatc ggttaaagta
    20821 gaatcaaaca gaattatcat ccaatttgct tcatcgttag aactggttgc tttcaagtag
    20881 ccagttttta cactttttat acccttttat taccaatttg gtttccattt tatacctttt
    20941 ttataccaat cacttaccta ttcaacgttg tattatgata gtgtcgaaaa attaggaaac
    21001 aggatcgaca aaataaaatg taagggagga aatctccctc atcgtttaat taagcttcga
    21061 taggcagcaa cggaaatatt aagaataagg atgtgaattt caactccttc taaattgttc
    21121 ttattatcta tcatccgttg ctgtctattg tttttttaat tattcacacg ataactaaag
    21181 gtaagtgaag agaaatgatt ccattaataa tttcaatttt tgcgctttgt cttaatgtat
    21241 atatgattgg atttaaaaat gggcaaaata aaaaatagta gcagccaaga ataattttat
    21301 agtgtcactg tggcggaaag ggtagacgct aagcatgtgt gctaggtcaa tgcttcggca
    21361 accatgcaag gttcgattcc ttgccagtga ctttggcaac cgaggcatcg gcggtttaaa
    21421 aatatagggg tgcgcaattt cgtacgcgtt ttgtgcatcg tgtaggttgc tattacataa
    21481 ctggttaggt tagattgaga tttgggattc ggtacaaatg aatcgtcaaa tgtctcaagc
    21541 acaggatcgg aaacgtccct gcctgtgcat tacatattag atcactcttt gagtggtctt
    21601 tttctttaca taaaggaggc tacataatga gaaactactg gtatgtatcg ctaactaatg
    21661 aatatcctcg aaccattgat gattgttcag tgcgtgttgt gcgttctgta caaatcaaag
    21721 ggaagtactc tattgtcgaa atggggagag aagcagaacc atgtgagatt gatgcgtgca
    21781 agctcgttta ttgcggtcat ggtttctatg atgaaccaaa cattcaaaat aatattaaca
    21841 agaatttgag ggattagaat gcaagaaatg gcttaaaaat ctccaatcag gacaaatcaa
    21901 gttagacaaa gtttccgatt taaagatatt gattgaagct gatttaatgc taaaagatat
    21961 tgaaaattag aaaacaaaac tcaacctaaa cagaatgtga ggtggtgtgt attgaatggc
    22021 aagacaacgt gatccaagac gtgatgaagc caaaagaatt tggttagaat ccaacggaga
    22081 aaagcagtta aaggaaattg catctgaatt aaatgtttca gattctcagg ttagaaaatg
    22141 gaaatcgcaa gacaaatgga gcgctgaatt gattagtaac gttaccaatg gcaaaagtaa
    22201 cgttactaat caaggtggcg ctcctattgg taatcaaaat gctaaaggta acaaaggaaa
    22261 tagccgagct tctccgccag tgggtaataa aaacgctttg aaaacaggtg agtatgaaac
    22321 aatatttttt gacacgttaa ccgataatga gaaggacatc tattctagtt tgaatgatga
    22381 tccttctttt gctttgtccg aagaaatacg acttcttaaa ataagacaac ttcgaatgat
    22441 gaaaagaatc caacaagctg aagctggact aaatgatgaa gaagtcgaac gattgcagca
    22501 gctaagaaag attaaaactc cgattgaaaa aaatggtaaa aagctagaaa tcaagcgtga
    22561 ggttatgcaa gatgtgcaga ttagcagaaa aaaacatcgc aaaattgatg atattctttc
    22621 aattgaagat tcattgactc ggattagcaa ccagttagct aaagccatca agcaaatgaa
    22681 tgaactttat atgaatgaat acagaactga tttaattaaa gctcagactg ataagatcca
    22741 agctgagaca aatgaaattg gcggaaataa ttcaggtgaa gaaatagaag aatggaaaca
    22801 ggcagtttta aatgccgcaa acaaacgggc ggtgaaagaa aatgaataat gaatttattc
    22861 cttttgctga tattggttct gccattgatt attactatga taaaccagta gctttttgcc
    22921 aagatatttt gcatttgaat cctgatgaat ggcaagaaaa tgttttaaat gatttagctg
    22981 aattttcaaa ggtttctgtt cgttctggtc aaggagttgg aaaaacagca ttagaagcag
    23041 gagcaatact ttggttctta acgtgtcgac cctacgctaa agtaatagca acagctccga
    23101 caatgaagca actttacgat gtactttggg cagaggtagc taaatggtta aatgatagct
    23161 tgatcaaaaa cttactgaag tggacaaaga ccaaaattta tatggttggt gattcagagc
    23221 gttggtttgc tacggctaga acagcgacta aaccagaaag tatgcaaggt tttcacgagg
    23281 accatatgtt gattgtggta gatgaagctt ctggtgtgtc tgatccaatt atggaagcta
    23341 ttcttggtac gctatcaggt tttgataata agctgttgat gtgtggaaac cccaataata
    23401 ttgaaggtgt cttttatgat tcccataatt cagaccgtga taaatacaga gttcataaag
    23461 tatcaagcta tgatagtaaa cgtacaaaca aagacaatat agaaatgatt cttaaaaaat
    23521 atggaaaaga aagtgatgtt gctcgtgtcc gtatttttgg agaatttccg aaaggtgcgt
    23581 tggattcatt tatcagtctt gaaacagttg aattggctac agaaaaacaa attagtgatt
    23641 ctttagtcaa taaaacaaag gttgctcata ttggtgtcga cgtagctcga tatggtgatg
    23701 attctacgat tctctttcct agaattgcta ccagggcatt ggagtatgag aagtattcaa
    23761 aacgtagcac catggaaaca acaggatatg tcatcaacat ggccaagaat ctaatgagtc
    23821 aatatccgag tattgataaa gtgatgatta aagtcgatga cactggtgtc ggaggtggtg
    23881 taaccgaccg cctagaagaa cttatagaag acaaacatta tccttttgag gtgtttggag
    23941 tgaataacgg ttcaacatca gaagacgatt tttacgataa tttaggtact caactatggg
    24001 gaaacatcaa ggaaatgtta gaagaaaata tgacagcaaa tcttaacgga gaacagcctg
    24061 ttattgaatt gccttctgat agttcgttaa tcaaagaatt aagtactcgc aaattcaaaa
    24121 tgacaagtag aagtcgtata cgtttagaaa gtaaagatga tatgaaaaag cgaaatattg
    24181 gtagtcccga tattgctgac gcactggctt tagcgtttta tgagccacca agtcactatc
    24241 aatttattca attttaggag gtgagctttt gattagtaca gtattatctt tagagagata
    24301 taagaagcta cgtgttaaat atgcaacaca aattgaagat ggaatgtttg atccgaatgg
    24361 ttttatagaa gatatgaaac cattttttgc tgatcgcgaa agaaaatatc tagcttatac
    24421 tagcgaaaag aatgaaatag ataatagacc aaagcctaac actgatattg taaaagttaa
    24481 taataaactt catgctggta tgtattcaat tgtcgtagac caagcagtca atcattttac
    24541 tggtatacct atcaaatggg attacgatgt atcggaacaa aaaagaacac tcattcaaag
    24601 attaaaagat aaattcttaa aaaatgatat agaacttccg acagttccag aagcttttaa
    24661 caaattaaca agcaatcttg attccatgag attcgcaatg cttgattctg aaactgcaac
    24721 ttttcaagga gcttgtggag tagctttccg attgctagag cctgtggaag aagatgatgg
    24781 ttggaagtta agagcaagta atattgaacc ttggagagca gaaagatatg gaaatgccgg
    24841 aatctatatc aaagaaaagt atgactctta ccagaaaaaa ttttttcaag aaatgaaagt
    24901 tatgacaaga aataaaattc tgacatatgc ttgctatggt gatttgaatt ttgttacaag
    24961 cggaacgttc aaaaaaattg atgagaccga taaccctttg gggacgatta ccttggcaga
    25021 atttaaaaat aatacgaatc gttattgtga ttttgaagta gctgaggaaa ttggagatgc
    25081 aattgatcgt gctttgtctg atcaacaaaa cgaaatcgaa caatttaagc ttgcgtacat
    25141 gcttgttact ggcacaacaa tgagcaaagg cactgctaaa gaaatgatga atcagctagg
    25201 gattatcaac ttaaaagccc ctactgcaaa agctgaatat gtcacaaaaa atttagcaaa
    25261 agatttcaat gaatatcata tggatctatt gaaaaaacag ttttacacca tttgtaaagc
    25321 aatcgatttt aacgatgagg tgtttaaatc aaacagttct ggagaagctc gcaagtggca
    25381 aatcattagc ctagaagcga aaacaaatac taaagagcaa tattttagag aaggattgaa
    25441 agaatgcgca gaaacaattg ctgcttttct taagtttcat gacaaagtag aaattgagcc
    25501 tgaaaaaatt atttttactt tctctagatc tttgccaact gatttaagtt atttagctga
    25561 agctttacct aaacttgcac catacgtatc caaacgaact attcagagcc aaattccatt
    25621 tgtaacagat gttgattatg aaaatgaaat gatggaattg gaaagtggaa gtgcttatcc
    25681 agatagtgaa tacaattttg gcggaggtgg caatagtgac gatagaaacg aagtattgga
    25741 ccaaacgtcg agaactggag gatcaagcaa ggctcaaaca agaaaatcag acacttaaaa
    25801 aattaactag tgtatttcct gaagcactga aagagataca agcaaaacta ttatcacaag
    25861 ctgacttaca caatatcact tatccagaaa tgatggagtt ttacagtaca agtaatcaga
    25921 aaaaatatcg tgaatatgtg gaaaaaaatt ataagtcatt aaaaatgtat gatgcaaaat
    25981 acaaagagtt tatcgatgaa ttttttccac catttgacta tgcaaaagtc aatcgcttat
    26041 tacaaatacg atcagatgta tttaaaattc ttgcagaata tgcgatggat gcagatgtga
    26101 atcaatattt ttctgatcgc ttagaggaaa ttcttcaaag aacatattct tctaatgcta
    26161 atgtttttgt tcaactttta aacgttgata taccaaatta tttaccagaa aatgaaatta
    26221 aacattattt gaactatcca tggtcaggaa agacattttc aagaagactt tggggaaata
    26281 tttcatcgct tgaacagaaa ctctctaatg ctattgtaaa aagtgttgct agtggagaag
    26341 gcgttataca cgcattaaac accatgagat tagactcaga aatttgtgac atgtttaagt
    26401 tagaagaatc aaagtataac aaagcgatag aaaatctcgt tcgaacggag tatgcaaaat
    26461 ttgcacaaga tggtattgaa aaatcatatt tagaaacagg tattgaggaa tacaacgtat
    26521 tgactgcaaa agatgagaga gtttgccgga tttgtggagg aaaggcaagt aagaatccct
    26581 ataaactgaa agatgctgtc ataggtgaaa atcgagcacc tttccatagt cgttgtagat
    26641 gtacggatgt tcctaattta ccaaaattag gaaaggatat tgatgaagaa tatgaccgtt
    26701 tatttggcga tttattagat gagtttgcac atgattcttt tggaattaat ttgaaacgga
    26761 ggaagtagaa tgaaagattt ttttgaagca gtactaacaa ttaatgtaaa tgctgatatt
    26821 gcagaagcct acaaaacagc tattgagtct gagaaccatc ctaatggctt gagagaccat
    26881 tggaatggca attatgccta cgtggttatt ggcgatcaaa ctgttaatta tcaagataat
    26941 actccagttg ataagaatac cgttaattta acgattcaat tattatctca ttcattacca
    27001 aatttaaaag aaacagttga ttggtatgaa aagatgggat gtattgttgt tagaactgac
    27061 tacaaagaag gaaagtctag taattaggct tttttatttt gtccgaaatg acgttaaact
    27121 agcgcaatac tgggcttggt tgaatggtgg ggcgcaacta ttaaaactca aagcaatgcg
    27181 gggcgtgaaa acgaatcgtg gggcgaaagg agaatgagca tgaaacacaa atcattaatg
    27241 ccaatgaatt tgcaatactt tgccgaaggt gacgatcaaa agttttcttt tgatgacttc
    27301 aaatcttttg tggaatccaa tgaagaagct caaaaattta ttcagtcaca atctcaaagt
    27361 gttgccgaca aacaattgga agcttggaaa caaaataact tagataaaat taaacaggat
    27421 accatcaagg aatatgagga atctaagaaa aacaagtcac ctgagcaaat tcaactggaa
    27481 aaactacaag ctgaatttga agcagaaaaa gcgttgcgtg tgacaagtga taataaagca
    27541 tttgttgcag aacaaattgc tggattagaa ctagatggag agttaaaaga gtctatttct
    27601 caatttatgc taaataatct tgttagttcg gatacagatt tcactaagaa tgctgttgaa
    27661 ggttttacaa gtgttttgaa tgcaattaat gagaaacatg cagatgcatt aaaagaacta
    27721 caaatgaagt ctgcatttgg tggaactcaa caatcgaata accaggttca gcagaacaat
    27781 gaaacattaa caaatccaga agaacaatta ggacaaattc ttcaacaatt taactaggag
    27841 agtgaaaaat tatgaaaaaa acatctttaa ataatttaga gtatttggat atttcaccag
    27901 cgattaatgc tatgcaagta ccaaatacac cttttttaag ctatttactt ggtgctggaa
    27961 aaacagagcc agcaaactcg acagaaatta aatggcgtga atatgatatc aacaacgatg
    28021 attcttctga aaaacttgag ggcggagaat atccagatgc tgaatcaggt cgaacttggt
    28081 ttaacaacta tactgaaatt tttagaaaat caacctctgt atctggtaca ttagatgcta
    28141 ttaatgtgaa tggagtcgga aatgaattaa ctaatcaagt agcactacgt ggtatggaaa
    28201 tgaaaattga tttgaaccga aaattgatta ctggtgtaaa agctgatgaa aatggttcta
    28261 aaggtcgtcg aatgaatggg attttgaact tgatcaattc agcaaataag gcagaaacag
    28321 ccactgcggg tgcagtaaca agaaaagata tcgatacttt atttaaattg atgtatgaaa
    28381 aaggttatat gggagaaaaa ctatgcttga tttctccaga tatgcaggag ttaatgactg
    28441 atgagttaga tggaaaatca acaaaaattg ttcagttcgg ggaaagagta acttttggat
    28501 tgcaaattgg aaatatcgtg tctaattacg gtacaggtat tgctctacta gaaccatcat
    28561 tgccaaaagg aacaattgcc gcaatcgata ctaattatgt gaaactacgt ccattacgtg
    28621 aatggagagc agaagaactt gcaaaaacaa cggattctag acgtatcggt cttgtaggtg
    28681 aatactctct tgaatacaat gcttcaaact ctggggcaat tttaaattta aagtctgaat
    28741 aaaagggagt tagtactccc ttttttgata ggaggaatta cagtggtaaa aaaagatgaa
    28801 actaaaaaag atgaagtcgt gaaatataga gtaggtaaaa ctaaaaattt tgttgggttt
    28861 gttcatccta aaactcgtag atttatcaca gcagattcaa ataacgaatt tatcatttct
    28921 atagatgata aagaagcaat tgcaattttg gaagatgcaa ttgatgttaa tgaaatttag
    28981 gaagtgatct gatggatgaa tcgctaaaaa cggaaatcat tgagtctaca aaagaagatt
    29041 ttccagattt gagtgaagaa cgcataacta atttattaga aataattttg ctagaaattg
    29101 aatcatacaa cacttgtaaa aatgatattt catgggaaaa gttaaaaagc gtgattagtg
    29161 aagtgttgta taaaataata aaaaatgaat cagaaaaaac agtatcttca gttagacgtg
    29221 gcgatacaac gattagttat gcttcaacaa caaatgatgt tagtgagtta cttctaggct
    29281 atggtgattt gatacgaaga gttattggtt gtggaggatt ggagtttttt taatgaatga
    29341 agcagatatt ttagaaacta cttatgaaga tagttgtatt attgaaagac tgacggacat
    29401 tgaagattct aatacaaata ttactattca agattacaaa aaagtatatg ataatcctat
    29461 ttcttgcgct ctttcacaag gtcaaatcga tggactagca gtcatagaag atggagagat
    29521 ggtaaatgtt tcaactgaca catataaatt atttgttcat cctaagatta aactaaaaaa
    29581 aggagatcga ataacaataa ctcaaaaggc cagtggctta attttttctc tatttgctac
    29641 taagcctttt tactatccta gtcattgtga agtgaatttg ataggaagtg agaaaaatgg
    29701 gtaatctcaa atatgaatca aatgcagaaa agatcattga gaattttaaa aatatgactg
    29761 taattgctca aaaagaagga atatccttcg ttaacgattc aatgaataaa gtcgttagtt
    29821 tagctaaacc attaactcct gtaaaatcag gtaatttaag gcgaggatat cgtgtagtaa
    29881 aagctagaaa actatcaagc ggtcgaattg ttggagaagt tataaacaat gaacattatt
    29941 ttaaatatgt agaagaaggt cataggacta aaaatggtgg ctttgtcaaa gggaaattca
    30001 tgttaactcg tgcaacgaat cttgcaaata tgtcttatat tcctcgaaga tttaaacaaa
    30061 tggcaataaa aatcgttaag aaaggaaagt aacatgaaag atgaaatcat tgctgcaatc
    30121 agtagcaaat taaaagaaat ctatcctgat gggacaatat atcttgattc agttatgcag
    30181 tcaactaaag atttttattt cgttttatca gtaatggaat ctggaactga aaatgtagga
    30241 attgatattc aaaatgtttc tttcttaatt gatattgcat tgattgataa taaccctaat
    30301 agaaatttaa ttaatgaatt agtctcacgt tgtgggactt tttttaatac gattacaatc
    30361 gatgagcaaa tattatttcc aaaagcctat ttacctgatg aagcagatgg tgttcaacat
    30421 attcgtttta cattagaatt tccacaatat attgaatgga gtgaaagata aatgggagaa
    30481 aaaagaagta aaaccggaat tatttctgtc gaaaaaccta cttggtttcc tttggaagat
    30541 gagacaggga attttccggt atatggtact gcgttgccaa tgggaacagc agtaagtatc
    30601 aaaccaacag ctaattatga aacaacacaa gattatgggg attcagtggt tcaagatcaa
    30661 tttacagctt ttggtggtgc agaagttgaa ctggaagcaa atggatatac tcataaagtt
    30721 ttatctacaa ttactggagg gaaaattgtt aaaggtggtg ccttgcgttc tggagaagat
    30781 attgcgcaag atggtgcgtt tgcatataga cgtaaaaaat cgaatgggaa ataccgttat
    30841 acggtctttt ataaaggaca gtttgctcta gattcagatg aaacatcaac gattgaagga
    30901 agtaaagtaa gttttactca tccaacttgg aagggttcat ttgtagatgt accaggactt
    30961 ggatatatgt attcagttga tgaagatgat gaaggcgtgg ataaagcaat gatcggaaat
    31021 tggtttacaa aagtagcaat tccaattgaa gaagcagaac tttcaggagg tacagaataa
    31081 tgtcaaaata tcaaacaacg attaaattaa cgaaaaaaga cgaagaaggt aaatatgagc
    31141 aagtacaatt taaatctgct gaatttttac caggaacagt tgtagaagat gctgcaggag
    31201 ttatggaaga aatgcaaaca gcgactgata agcaatcagt taaaaaagct ttaagtcgtg
    31261 cttattcatt tattgcagat actttatttg agggacaatt tactggtgaa gattattgca
    31321 aaggaattga tgctcgtgag attgcctcat tgacaggaaa attattgaag tctgttactg
    31381 caggttttga tgaaacttat acagagacga aaaaaaagta agtgaggcgc tcaagtcacc
    31441 ttcatttaag tattcgatta cttaccgaga attagatata aagacgcaat tactcgaagc
    31501 aggttggacg ttaccagaaa ttgaacgtac tgacttggat gagttaatgc gtctttttgc
    31561 ttttagagat gcggtaaaag agcatgaaga tgttgagtac tatgataatt tcactcaatt
    31621 ttaggaggtg atactttgaa taacgatgac ctaattctga agatgatact agatgaatct
    31681 ggttttactg ccggtatgaa taatgctgtc aaaaagttga actcttttga tgaaacaatc
    31741 gaaagaaaaa gtagaaatag tggcagttca ttaggtagta tttggaaaat atttgctgga
    31801 agttttctag ctagcggagt aactagaatc gtaggagctg gctttgatct aatcaagggt
    31861 tccataagtg gagcggttga tcgagtagat acgatgaata acgctctacg aaatttccaa
    31921 aatatgggat ttagtaattc agaaattatg aagaatatcg gaaagaatgg gcttttatct
    31981 caaggtattc aaggacttcc tactgctttg aatgatgcga taagtcatgt tcaacttctt
    32041 gcttcttcta caggtgattt aactcgttca actcaaatat ttaaagcttt aaatgatgga
    32101 attcttggtt tcggtggttc aactgatcaa gttaatgaag ctgttattca attatctcaa
    32161 agtttctcaa acggaaaagt agacgcacaa acttggaact caatgatcaa cgctcaactt
    32221 ggacctactc tttctgctat tgctaaaaag atgggaatta caatgggaga tctgaaagaa
    32281 ggtttatctc aaggtaagat ttctgttgaa gaattccaaa atcaattaat agaaatggat
    32341 accaaaggtg gcggaggact taaatcatta agtcaaatcg ctaaagattc tactaaggga
    32401 attaaaacct ctatacaaaa tgcaaaaaca gctgttacac gtggtgttgg tgaggtaata
    32461 gaaggattaa ataaagcatt agtagattca gatttaggtg gatttaaggg aattattgat
    32521 aaagtgggca gttcaatgga atcgttctta aaagtaattg ctgcaaatat tcctacagca
    32581 gtatcatttt taagtaattt atttaacgaa attcaaaaat ttggttctgc tttgaaattc
    32641 atgatgccct ttcttgttcc tgcagctacc gcttttggag cgttcatgtt tcaacttaaa
    32701 ggtataccag caataataaa aagcttcaat aattttaaga atgccataat tggcgttgga
    32761 aattcattaa agattatggg ggcaatagct gctgctaatc catttgtttt aattattggt
    32821 gcagtcgttg gtgcaatagc tgttttcggt tactttatgg caaccaatga agagcttaga
    32881 aacaaggtta tatctatttg gaatgatgtg aaagattccg taattggtgt attaaaaaat
    32941 ataaaggact ggggaattga tacttggaat tctgctaaag aaatggcatc aaatgcagtt
    33001 gagggtgtca aagatgcttg gtcaggaaca aaggaatggt tttctaacac ctggaaaggt
    33061 attaaggatg gggccacagg tttatttgat aaaacagtag agacttcaag aaatgcagtc
    33121 gatagtgtaa aaaatgcatg gtctaatatg aagaaatggt tttctgatac ttggcaaagt
    33181 ataaaagatt cagccagaga aaaatggaat ggaatcaaag gttctattat gtcagttgct
    33241 ggtccattga ttacaggtat aaagaatgca tttttacatg ttacttttta tctagagacc
    33301 ttatggaata atttagttga gattggtaaa aacgtctttg agattttaaa aaatgttata
    33361 cttgcgccgg ttttgtttat tacctccatg atttctggtg gatgggaaga aacaaaaaat
    33421 aatatgattg ctgtttggaa taatattaaa gaaagtgcca taaatatttg ggaatctata
    33481 aagaatatat ttgtaagtta ttttacaaat atttattttg ctgcactcaa tatttggaca
    33541 gggttcaagc ttacattgat aaatatttgg aatgaagtgg taaatcaagc taaatcgatt
    33601 tggttaaaca taaagtattt ttttattaat ctttggattg atataaaata ttttgcaatt
    33661 cagaaatgga ttgaattgaa gttttctatt attcaaactt ggatcgattt aaaatataat
    33721 gccattacta cttggaataa tattaaacag tttttcaaag atacttggaa aaatattaaa
    33781 gatacggcat acaatacgtg gatttctata aaaaatacca tgattaatac atggaataac
    33841 attaaggact ctttctggaa tattgttact ggaattgtta attctgctga aaatgcatgg
    33901 acaaatctaa aaaatggtgt ttcaaatgct attaatcggg taaaagaaat ctttaattcg
    33961 ttaagggaag tcaatttatt tgaaattggc aagaacatca ttgatggact tataaatggt
    34021 gtaaaagaaa agtggaatgc tttgaaagat actatcaaag gtattgcagg taatatcaaa
    34081 aattggatta aaggagcttt agatattcat tctccatcaa gatggatgcg tgatatggtt
    34141 ggtaaaaata ttgttcaagg tattatcgtt ggtattgata aagagcaaag taagttagat
    34201 caaaccatga caaatttagt aaaaacaccg tctgttcaac ctgtagtaaa tggaataagt
    34261 cacctaccaa ttacacaaac aaagcaaaat atatctgcta gtgaaacaaa agaaattcat
    34321 ttacatttaa atgtttatgg agatttacct gattcaatgg ttcggaagat taccacaaaa
    34381 attaaaacag aattgacaag acaaatgaaa cgagatgctg gtgcagtagg aggaacatta
    34441 tatgcaactt aagagaggac aattttttat taatcaacat tattcttctg aatttaatgt
    34501 gtatattcaa aacaggcctg cttctgtttc agctagtcga gtaattgaat tgagagagcg
    34561 agaaggaaat gattctatca ttattgataa aggctattac aaaaatgtga ctagaaagat
    34621 tgagtgttac tataaagcac cttcaattga tatggtgcag gagtgggaag atcgaatcac
    34681 tgaatggtta gatatgtcgt cttatagtga ttttattctt tactatgatg aacaatatat
    34741 ttatcaagct gtagtaatag aaggacctga atttaaagga acaagaaaaa caggaaatat
    34801 tgtccctttt gaatttacag tgagtattcg accatttaag gaaaattaca atggtagatt
    34861 tactattcga caaacagaaa cttttgaaat ttataaccca gagaagtatt cttcaaaacc
    34921 gcttattaaa ttgagtggtt ctggagatgc ttctttttat attaataagg ataaatatga
    34981 tttgaaatcg ttggacagag aattatttat agattctaaa ttagaagagg cttatcgaaa
    35041 attagatggt aatttagaac atcaggatca ggtcacctta tttttagatt ttccattttt
    35101 atatcctgga aaaaatgaaa ttaaatggac gaaaaatatt cattcatttg aaataatgcc
    35161 taggtggtgg agaaaagtat gaaaccaaga atatatagtc ctactgaaac agatttctca
    35221 acgaatggct taggaatttt aaaggattgt acaagatgtg gaatatatga agtagctaat
    35281 ggaaaatatg aattagagtt ggattatcct ttaggaacta gatttgatga atattttgaa
    35341 aatgactatc aaataaaagc aaagccaaac gatcaagaag agtatcatat cttttttatt
    35401 gatgataaag atatagatac ttttttaaat acagtaacta tttatgctca gagtcgtaca
    35461 aatcgacttg gaagacgggt agtcactctt gtggaagtgg actctaaaac tggtcaagaa
    35521 gcgatatcaa ttattgaaac taaaatggat aaaaaatctg acatacgact ttattctgat
    35581 attacggctg tttctagcac aatctttgaa gcgagaaatg ttttaaattg tattgctggt
    35641 gaacaaggat cattgcttca atattggggc ggagaaatta aacgtgaacc atttaagctt
    35701 tctttgttaa agcgaagagg tcgcaataat gttggaacga ttcggtatgg aaaagatatg
    35761 tctggtttga aggtcaaatt agattggaca ggtataaaaa caagaattat tccatatgct
    35821 gatcctcaaa gtgaagtagg tacgactaat cgaatttatg gttcgccagt agatagtgcc
    35881 tatattaata actatcctga tgtctataca gaacatgttc agtttacaga agaacaagga
    35941 gtaaaagaca ttaagagctt aaataaaata gctaaaaatt actttaaaac gatcaatcct
    36001 ggctgtgata agcctaaagt ttctattacg gttgaatttg ataagttgac tgatagtgaa
    36061 gaagcgaaag aatttgcgaa gattagaaat tatggtctgt ttgatacatt taaaatatat
    36121 cataaaaaat ataatattta tcttgaatca aaggttagtg gactacaata cgattcttta
    36181 tctgaaaaaa ctttgaaatt agaagcagga gacattcaag ttgcttttta tcagcaacaa
    36241 gctgtaacta ttcaggataa attaaaagat tatgcaacga ataattatat gagtgatttt
    36301 aatgattatg tttcttcaat gattacaggt caaggcagtg caggaggata tgtagtttta
    36361 tggccaaaag aaaaaccttc caacatcttt attatggata atccagattt agaaaaggca
    36421 agagaagtac taagaatgaa taaaaatggg attgcttttt ctaagaaagg atggcggggg
    36481 ccttttaatt cagcttggac attagatagt atatttaatg ccaattttat acaaactgga
    36541 ttaatcaaag cagatatctt tcaaaattct tttaacaaga ctggagatgt attgaaatta
    36601 gttaatggac tactccaaat ttggaacaac aaaaagaaaa taatggagtt aactaaaaaa
    36661 ggaatggaat tttggaattc taagggttca attggaacga ttggaacaac tgattctgtt
    36721 ggtaatcctt ttcctggggc ttctactcca acccctattg aagataattc tttagttatt
    36781 cgtacaaatg gagacggcaa atatattttg atttctccta aagtaggaaa aggattagtt
    36841 ttattaggaa atggtaaagc aatttatttt ggagacttag atgtacaagg aaaacttaca
    36901 gttaaaggaa aagaaataat tcctggacaa ggtggtggtc catcgggagg tggagaatct
    36961 actggtgggt atcctagtga attaaaaaca gatgcagaaa agagagcttg gagaat
//
LOCUS       DADQDV010000022        36568 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.022, whole genome shotgun sequence.
ACCESSION   DADQDV010000022 DADQDV010000000
VERSION     DADQDV010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 36568)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36568
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.022"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(26..1522)
                     /gene="lysS"
                     /locus_tag="J8S10_001194"
     CDS             complement(26..1522)
                     /gene="lysS"
                     /locus_tag="J8S10_001194"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HAZ9629784.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKTGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(1633..2637)
                     /gene="dusB"
                     /locus_tag="J8S10_001195"
     CDS             complement(1633..2637)
                     /gene="dusB"
                     /locus_tag="J8S10_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HAZ9629785.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVDCREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(2638..3525)
                     /gene="hslO"
                     /locus_tag="J8S10_001196"
     CDS             complement(2638..3525)
                     /gene="hslO"
                     /locus_tag="J8S10_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HAZ9629786.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(3742..5853)
                     /gene="hflB"
                     /locus_tag="J8S10_001197"
     CDS             complement(3742..5853)
                     /gene="hflB"
                     /locus_tag="J8S10_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HAZ9629787.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(5943..6488)
                     /gene="hpt"
                     /locus_tag="J8S10_001198"
     CDS             complement(5943..6488)
                     /gene="hpt"
                     /locus_tag="J8S10_001198"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HAZ9629788.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6488..7933)
                     /gene="tilS"
                     /locus_tag="J8S10_001199"
     CDS             complement(6488..7933)
                     /gene="tilS"
                     /locus_tag="J8S10_001199"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HAZ9629789.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8053..8523)
                     /locus_tag="J8S10_001200"
     CDS             complement(8053..8523)
                     /locus_tag="J8S10_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HAZ9629790.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(8569..8994)
                     /locus_tag="J8S10_001201"
     CDS             complement(8569..8994)
                     /locus_tag="J8S10_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HAZ9629791.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9061..9330)
                     /locus_tag="J8S10_001202"
     CDS             complement(9061..9330)
                     /locus_tag="J8S10_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HAZ9629792.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9341..10936)
                     /locus_tag="J8S10_001203"
     CDS             complement(9341..10936)
                     /locus_tag="J8S10_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAZ9629793.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(10951..14472)
                     /gene="mfd"
                     /locus_tag="J8S10_001204"
     CDS             complement(10951..14472)
                     /gene="mfd"
                     /locus_tag="J8S10_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HAZ9629794.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14489..15049)
                     /locus_tag="J8S10_001205"
     CDS             complement(14489..15049)
                     /locus_tag="J8S10_001205"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HAZ9629795.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15402..16376
                     /locus_tag="J8S10_001206"
     CDS             15402..16376
                     /locus_tag="J8S10_001206"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HAZ9629796.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            16546..17946
                     /locus_tag="J8S10_001207"
     CDS             16546..17946
                     /locus_tag="J8S10_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase family protein"
                     /protein_id="HAZ9629797.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18024..18746)
                     /locus_tag="J8S10_001208"
     CDS             complement(18024..18746)
                     /locus_tag="J8S10_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAZ9629798.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(18825..19331)
                     /locus_tag="J8S10_001209"
     CDS             complement(18825..19331)
                     /locus_tag="J8S10_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HAZ9629799.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSIDHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19454..21253
                     /locus_tag="J8S10_001210"
     CDS             19454..21253
                     /locus_tag="J8S10_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HAZ9629800.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21321..22895)
                     /locus_tag="J8S10_001211"
     CDS             complement(21321..22895)
                     /locus_tag="J8S10_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629801.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23150..23659)
                     /gene="mreD"
                     /locus_tag="J8S10_001212"
     CDS             complement(23150..23659)
                     /gene="mreD"
                     /locus_tag="J8S10_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HAZ9629802.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(23663..24517)
                     /gene="mreC"
                     /locus_tag="J8S10_001213"
     CDS             complement(23663..24517)
                     /gene="mreC"
                     /locus_tag="J8S10_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HAZ9629803.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(24672..25310)
                     /locus_tag="J8S10_001214"
     CDS             complement(24672..25310)
                     /locus_tag="J8S10_001214"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HAZ9629804.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25311..25961)
                     /locus_tag="J8S10_001215"
     CDS             complement(25311..25961)
                     /locus_tag="J8S10_001215"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HAZ9629805.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGQFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(25974..26873)
                     /gene="rsgA"
                     /locus_tag="J8S10_001216"
     CDS             complement(25974..26873)
                     /gene="rsgA"
                     /locus_tag="J8S10_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HAZ9629806.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27038..29107)
                     /gene="pknB"
                     /locus_tag="J8S10_001217"
     CDS             complement(27038..29107)
                     /gene="pknB"
                     /locus_tag="J8S10_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HAZ9629807.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(29104..29844)
                     /locus_tag="J8S10_001218"
     CDS             complement(29104..29844)
                     /locus_tag="J8S10_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HAZ9629808.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(29857..31215)
                     /gene="rsmB"
                     /locus_tag="J8S10_001219"
     CDS             complement(29857..31215)
                     /gene="rsmB"
                     /locus_tag="J8S10_001219"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HAZ9629809.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKTLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31215..32153)
                     /locus_tag="J8S10_001220"
     CDS             complement(31215..32153)
                     /locus_tag="J8S10_001220"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HAZ9629810.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKEAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(32146..32637)
                     /gene="def"
                     /locus_tag="J8S10_001221"
     CDS             complement(32146..32637)
                     /gene="def"
                     /locus_tag="J8S10_001221"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HAZ9629811.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(32652..35060)
                     /gene="priA"
                     /locus_tag="J8S10_001222"
     CDS             complement(32652..35060)
                     /gene="priA"
                     /locus_tag="J8S10_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HAZ9629812.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(35313..35618)
                     /locus_tag="J8S10_001223"
     CDS             complement(35313..35618)
                     /locus_tag="J8S10_001223"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HAZ9629813.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(35623..36237)
                     /gene="gmk"
                     /locus_tag="J8S10_001224"
     CDS             complement(35623..36237)
                     /gene="gmk"
                     /locus_tag="J8S10_001224"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HAZ9629814.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYINKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEERMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
BASE COUNT         9886 a         7988 c         6705 g        11989 t
ORIGIN      
        1 aattccttag acagctttta ttcgattatc tcattgttgg gaatagcaaa acatcccgaa
       61 ttgattgtgc atcagttagc aacattacta atctgtcgat cccgatgcct agaccaccag
      121 ttggcggcat accgtattct aaggcttcca agaagtcttc gtctacaccg tgagcttcgt
      181 catttcctag ttcacgttct ttttcttgcg cttcgaatct ttctctttga tcaattggat
      241 cgttcagttc tgtaaaggca ttagcaaatt cgcgccccac tatgaatagt tcgaatcgat
      301 ctgtgaatcg aggatcttct ggatttttct tcgctaaagg cgaaacttcg actggatgtc
      361 cgtatacaaa cgtcggttgt gtcaatgttt cttcaacaaa tgtttcaaag aattcattga
      421 taacatgtcc gacacccata gcttcggtta cttctacatt gtgtttttcg gctaaagcta
      481 atgcttcttc caatgtcatt tcttgccaga agtctacacc agtttgttct ttgattgcat
      541 ctaccatatg gatgcgttta aagtcacttt ctaagtcgac agcttgtcca tcatatgtga
      601 tttttgctgt tcctagtact ttttcagctg cgttacggat aataccttct gtcagattca
      661 ttacatcatt gaaatcagta tatgctgtgt atgcttctaa catcgtaaat tctggattat
      721 gtgtagtatc aattccttca ttacggaaaa cgcggccgat ttcataaact ttttccattc
      781 cgccaacaat tagtcgtttt aaatgaagtt ctagcgcaat acgcaaatat aaatcaatgt
      841 ccagtgcatt atgatgcgtg ataaatgggc gtgcggcagc tccacctgcc tcattgtgca
      901 atactggtgt ttctacttca atatagccat tgccatctaa atagcgacgg atttcgctga
      961 taatttggct tcgtttcata aatcggtcaa agctttcgcg attactgatt aaatccaagt
     1021 agcgttgtct gtagcgttgt tcaatattcg ttaagccatg gtatttatct ggcagtggac
     1081 gaagtgcttt tgacaaaatc gtgatttctg aagctttgat agaaacttcg cctgtgtctg
     1141 ttttcatgat ttgtccagtt acaccaaaga aatctccaag gtctgcatgt ttgaatactt
     1201 cataggcctc atcacctact tggtcttttc ttacataaat ttgaatttgg ccttcacgat
     1261 cttgtagatg cgcaaatcca gttttccctt ttcctcggcg agtcatcata cgaccagcta
     1321 cactagcggt caatcccatt tctgctagtt cttcttttgt tcttggatca aatagttcat
     1381 gcaattcttc tgagttgtgc gtgcgttcaa atcgttttcc aaatggatcg attccatctt
     1441 cacgcaattg ttccattttt tgacgacgta caagcatttg atcatttaaa tcttctactt
     1501 gatgttgttg ttcctgtgtc acaaaagttc ctccattctc atgttaatct ctttcctata
     1561 atgccaatga aacacaaaaa aagcaagccg aacttggaat ttcggcttga aaattcacga
     1621 aaaacttaga aatcacaacg tttgtttcaa tagtactttt tccgcttttt ctacaaattg
     1681 atccagcagg tcattgattt cttgctgttt ttctgtctga ttgattgcta ctttcacttt
     1741 cgctgctcga ggaatccctt ttaaataata agccgcatgt gttctgaatt ctctacaatc
     1801 tactttttct cctttgagat ctgctaagcg ttgtaaatga agtttagctg tagcaatttt
     1861 ttcggctggt gttggttcag gaatcagttc tcctgtttcg agataatgct gtgtgcggtg
     1921 aatcatccat ggattgccca gcgctgcacg accaatcatc acaccgtctg caccgacata
     1981 gtcaagcatc cattttgcat cttctggcgt tttgacatcc ccgttcccca taaatgggat
     2041 cgtcaaatgt tttttcactt ctttcaatac ttcccagtcc gcttttcctt catacatctg
     2101 aacccgtgta cgtccatgca tagcgatggc acttgctcca gctgattgtg ctgctaatgc
     2161 attttctaca gcaaagacgt gctcttcatc ccaaccaata cgcatcttga ttgttactgg
     2221 gatatttact gctgaagaaa cagcttggac catttcgtat actttctcag gatctaaaag
     2281 ccattttgct cctgcttctg ctttgattac tttatttact ggacagccca tattgatatc
     2341 tattatatcg gcagctgtgt tttcttcgac aaattgagca gcttcaacta gactatcttt
     2401 atttccgcca aatatctgta aacttaatgg atgttctgtt tcttcaatgt ggagcatctc
     2461 taaagttttt ttgtttctga aatgaatacc ttggtcactg atcatttcac atacgactaa
     2521 gcccgcacca aattctttga cagtgactcg aaatgctgaa tttgttattc cagccatcgg
     2581 tgcaacaacg acacgattag ggatttccac attgccaatt ttccatgtgt gttccactta
     2641 aatccctcct aaggcttctt tcttcaatcc atctaattct tcttcgctat acttgtattt
     2701 gttattacag aaagaacaaa ccgcttctgc accgtgatct tcgtctatca ttgcttggat
     2761 ttcttctgca cctaacgcga taattgcttc tgcaaatttt tcttttgaac agtcacattt
     2821 gaattgaaca ggcatttttt ccaaaatgtt caattcttct gtaccaagca atcctttcaa
     2881 tatttcttct ggtgtctgtc cttcatctaa gagggtagag attcttggtg tcgtttttaa
     2941 ttgttcttcg atcttgctga ttgtttcttc atcggcacct ggcatgattt ggatcatgaa
     3001 tcctcccgcc gtcttgatgc tgtcgtcagt attgaccaat acactcagtc caacagctga
     3061 agggatttgt tctgagatag caagatagta agtaaaatct tcagcgattt ctccagaaac
     3121 aatcggcgtt tgcccagaaa aaggttcttt taatcctaag tcttttgtga cagtaaacat
     3181 tccttgtgtt ccaactgctc cccgcacatc gattttacct tcactattta gaggaagact
     3241 gagatgcgga tttttgatgt aacctttcac atctcccttt ccatttgcat ctactacaat
     3301 tcctgttgct ggaccatcgc cttggattcg aacagttagt ttgtcttctc ctttgagcgt
     3361 cgcaccaagt agcagactac cgaccaatgt ccgtcccaaa gcagctgagg aggtgtgcca
     3421 agtatcatga cgtctttgtg cctccgctac ggtatttgtt gcttgaacgg cgtatgctcg
     3481 gacgaatccg tcgtgagcaa gtgccttaac caaataatct ttcatttgtt atgtactcct
     3541 ttttccgttt ttaaactcat agtgaatcat actagcaact actgcttttt tcaactttgg
     3601 aatgcttctt ttaaaaataa ttcagaatca tctagaaaac aggacatcac cctatttaca
     3661 acttaaataa agaaatctcc cgaaaaccgg tttttgttcc ggttttcggg agtcatatca
     3721 gatcaattga cctatatttt tttatttgta ttgatcgtct gaatgattat cttctgattg
     3781 ttgagaatct gaatcatgtt ctgctttatt ttcctcattc agttcatgtt ttgcttcttc
     3841 aaaatcacgt ttttcttccg cttgtttttc agcgtctttt tcttccaaag cacgttttgc
     3901 ttcttcaaaa gttttcgctt ctttttcgct tggataatca tttgactcag taccttcagg
     3961 catcacaccg tgttcaaaca atgacttgat tgctttggca tccaatgttt cgaattccaa
     4021 aagtttttca gcaatcagtt tatgctgtgc acgatgagct tcgatgattt ctcgagcttt
     4081 atcatgagct tccatcaaga tttttcgtac ttcttgatca atctcgaaag cgacttgttc
     4141 cgagtaagct tttgtttgac catagtcgcg gccaacaaac acttgatggt ttccttcata
     4201 ttgaacagga cctaaacgat cactcattcc atattctgtt accatgcttc gtgctagagc
     4261 tgtcgcttgc tcaaagtcat tggaagcacc agttgattgg acattgaaga tgatttcttc
     4321 agctgtacgt ccaccaagta agcctacgat ttgttcaaac atatcttctt tcgtcatcaa
     4381 gaactgatct tcttttggta aagcgatcat atatccgccg gcgcgtccgc gagggatgat
     4441 cgttactttg tggacgaccc gagcgcgact caatactaat ccgacaatcg tatgaccagc
     4501 ttcgtgataa gcaaccattt cgcgttcttt tttgctgatt acgcgatctt ttttagctgg
     4561 acctgcaatc acgcgatctt ccgcttcatc gatatcagaa gcatcgattt tctttttatt
     4621 tcttctagca gctactaacg ctgcttcatt caagacattt tctaaatctg ctccggcaaa
     4681 acctggtgtc tgttgagcca caactttcaa gtcaacgtca tctgccatcg gtttattccg
     4741 tgcatggact cgcaagattg cttcacgacc ttttacatct ggacgtccaa ctaaaatctg
     4801 gcggtcaaaa cggcctggac gtagtaacgc tgggtctagt acatcagaac ggttggttgc
     4861 agcaatgacg attactcctt catttccgtc gaagccatcc atttctacaa gcaattggtt
     4921 caatgtttgt tcgcgttcat catgtccgcc gcccataccg gcaccacgtt gacgacctac
     4981 cgcatcaatt tcatcaatga aaatgatagc tggtgcgttt ttcttcgctg tttcaaacaa
     5041 atcacgaaca cgacttgctc caacaccgac aaacatttct acgaaatcag aacccgagat
     5101 cgagtaaaac ggtactccag cttctccggc aacagctttt gctaataagg ttttacctgt
     5161 tcctggaggt ccttctaaaa gtacacctgc cgggatacgg gcacctaatt caacaaatcg
     5221 gcgaggatct ttcagaaatt caacaacttc aactagttct tgtttttctt cttccgcacc
     5281 cgctacatca gaaaaacgta cgcgattagc ttttttgtct gcttctttgg cttttgattt
     5341 accaaagttc atgacacggc cgccaccgcc accgccgccg ccttgttgtc ccatcatcat
     5401 gtaaaagaaa aagatgatga ttacgattgg caagaagcta agcaataggg aaacccatat
     5461 accgctgctt gattcttctt ttactgttgt agcaactttg ttttcttttg ccagttctgt
     5521 tacttggctc aatgttgtat catttggcaa aatgattgtt gtgaaatggg tagtagtcgt
     5581 atctgttgaa cctaagatag ctaacccacc gctgttagcg acggtctgct gttctttgta
     5641 ttcaccagtg atcttatata caccatttgc aggctgcact tcaaattctt tgatcttgcc
     5701 tgcttgtagt tgttctgtga attttgagta ctcgatatct gacgatcgct ggccgttatt
     5761 accaaaaatg aaataaacga ccattaccat cgctaagatt acgaggacat aatacaaggc
     5821 atttttcatc atgccgttgt tctttttgtt catagttgcc ctccctaagc gtcaatttaa
     5881 tttaacagtt ttttatcaat cctgaccatt ctattgtacc ataatttaat tgagatacag
     5941 cattaatttg attgataaac actaggtttc aatacaccga tgtacggaag gttacgatat
     6001 gcttctgcat aatccaagcc ataaccgacc acaaattcat ttggtacgtt gaagccaaca
     6061 taatctgctt cgatatttac tactcttcct tcaggtttgt caagtagtgt aacaattttg
     6121 actgattttg ctttgcggta tttgaaaaga tccactaaat aagcaagtgt tcttccgctg
     6181 tcaatgatat cttcaacgat caacagatcg cgaccttcta cattcgtatc taagtctttg
     6241 acgattttta cttcccctga cgagactgtt gcattcccgt agcttgaaac atccatgaaa
     6301 tccaattcca aatacgtatc gatagaacga acgatatctg ccatgaatgg taccgctcct
     6361 tttaagacac ctactactag gggattggtg ttttggtaaa tttctgttaa ctctttgcct
     6421 agttctttgc aacgaacttg tatctcttct tgtgagatca aaattctctc aatatccttt
     6481 tccaacatca ggttctcctt ccaattgctt ctttttgata tttgtaaaga agtatgtagt
     6541 gtattttatc agtttcttca cgaatactca aatatgaaaa ggcaaaaggt atcaagctat
     6601 atatatttct tttggcatct gtaatgatcc aagcatgctg cctttgtgaa ttaggtactt
     6661 tctgatcgat aaaatatcta gatacttttt ttgtgagatt ctctgttaat ttaatgcggt
     6721 ctcctgcttt tcttttttcg acatacagtt gcacatcagc aggaatccaa atgtcatgag
     6781 aaaatagaga ccatgaatct gttgctttga tgtcccctgc attttcaggt ttgaccagac
     6841 caatccattc tgtttcattc aaatatattc cttgttctgg aatcagcaac aagcgctggt
     6901 cttctgtctg gctagttgct tgtttttctt ttttagagag tacaacaaaa tgatactctc
     6961 ttttcagtat ccaattattg ccaatactga gttgccattg gctttttttc tgttgccact
     7021 ggtctaaaat cgactccatt tgttgttctt tcaaaataat tcctgttttt gagaatgctt
     7081 tgtcgaaaaa ggagtaaaaa aaatagtatc gttcagcatc tgtcatttct tcaatcattt
     7141 ctgcagaaaa tcgaaattgt tcctcccact gttcgacttc cttttcgatc aactgtccca
     7201 tatatttttg aatgacttgg tctgcccatt ggatctgttg cgaaaattgc tggaaatgtc
     7261 tcaacgcctg tgtattttct tgtttcaatt gaggaactac caaatgacga agccgatttc
     7321 tctggatatc taacaattgg tttgtctgat cctcaaagta aacaagctgc gattccgctg
     7381 cataagtata taggtcttct ttgctaaaac tcagcaacgg acgaatcagt ctgcccgtag
     7441 caaatggttg tacttctttg attccagaaa aagtatttaa ctgtccccca cgaacgattt
     7501 tcattaacac cgtctcgatt tgatcatctc cgtgatgagc agtcatcaac gtgtcatatt
     7561 gtccttcttc catcacgcga gtgaattctt gataacgaaa gttacgagct tctgtttcta
     7621 tggcggattt ggctggatct tcccaaatac ttacatataa agggagattc ttctcttcac
     7681 aatatgagcg aagataggca gcttcttctg ctgattcttc tcttaattgg tgattgatgt
     7741 ggacgatacc taaagaaaaa ccgatttggc gttgcacttg taaaagtaaa tggagcaaaa
     7801 ccatcgaatc aacaccacct gataccgctg ctaaaattct cgatccttgt tgccagaatc
     7861 cttgttcatt cccgtgccga ataaatgact gctgtaatag cggtgctttt ttcccgcctt
     7921 tttcaacgtt catcctttcc acaccctttc ttcctaaaaa aaagagagcg ggaaaacgtc
     7981 taaaacgaca attaacctgc cctctgttga tactatgacc caaatagtcg cactatcatt
     8041 atttgcggct ttttagctgc gacgtccgcc acggccaccg cgctttcctt ctgtgtttcg
     8101 cttcaatgaa gataagcggt catcgctatc tttcaaaaat gaactcatca atgaatcgaa
     8161 gtcttctttt tgagctgaag gttgactgcg agaaaaagat tttttctgtg ctggacgatt
     8221 tcggttgtca cggggatctt tttgttgata ttttttagga cggctttctt ctccagattc
     8281 agcaggttgt tcctgcgctt tccggataga tagtccgatt tttccatcat catttactga
     8341 aataacttta actgttactt catctcctac acttaaaaca tcatggatgt cttttacata
     8401 gccatttgac acttcgctaa tatgaactag acccgttttt ccagcaccta gatcaataaa
     8461 cgcaccaaaa tttgtgattc ctgatacttt tccttgcagt tttgctccta cctcgattga
     8521 cataaaaaaa atgttcctcc taattatttc ccttttttat attcctgctt attttgcagt
     8581 tgtagaacta gttgattgat ctgtttcatt tgtcgagctg tctgtatttg attctaatat
     8641 aggataaact ttttcaccgt cttttgagta aaagaatttg cttctggcaa gtttagctac
     8701 atactcatca tctttcagca atgaaacatc ttggtgcagc tgatcaacgt ctgcgttgac
     8761 ttctttcatt tcagtatttg cttcgactct caattcgttc aattgatgca tcctttgcat
     8821 gtcatggaaa atctgcacac ctattatcgc gaaaatgacc aaagcaccaa caaaaattgc
     8881 agccagtctg cgtcttcgaa aaatcagttg acgttgttgt tgctgaaatt cagcatactt
     8941 tttctttgca tattccgtat ctagcgcagc gattttattg ctttttttcg tcacttggat
     9001 tcgctccaat ctttttgatt gtctttttca ttataccaat atcgtgaaag cttgtctaat
     9061 ctatttctct agtgtttctg tgcgattttc agaaataatt tcgtacattt tttgtgcatc
     9121 ttcttttttg gttgattcat gtaattccgt aattttcact tccaacgttt tgttgccaaa
     9181 ctggactttc aaaatatcgc ctactttgac atcactggaa gatttcgcca atttaccgtt
     9241 gatttgaatt cttcctttat cagctacttc ttttgctact gatcgtcttt tgatgattcg
     9301 ggaaattttt aaaaatttat ctaatcgcat atcttattcc tcacttttta atttttttat
     9361 ttaatcgcag gattttctta ccaaaaggca acattagcca ttctcgtact gtaaacagac
     9421 gaagacgaat cactgcataa atgaacacag aagccccgat cccaactcct atcacgctga
     9481 caaaaaaagc agtggaacga tgagttacag gaccaaatac tatattcaat acaccataat
     9541 acagcagcag tactactgtc atacaaagaa ggctgaacat caacttccgt ccaaaatgcc
     9601 gttctttcca aaaagcattt agctcttttg tttcaattcg aacaaaatac caaagcgtca
     9661 cacctaatcc taaaagggta gacaggcttg cacctgctgt tcctaataaa ccggtcagaa
     9721 aagaagtagt caatcctttt accaatagtc cccatcctgc gccttttaaa gaagggcgaa
     9781 acgagttctt gctttgagca atactttgat aagcttggat gactgcagtg aaagcaatgg
     9841 aaaaaacaaa taatacaagc gctgcatttc ccgcataatc tttaaacaac gcataattga
     9901 tataagggag cagcaaggct aatcccaaag acgcagctaa tgctaaagcg gtcgtcaatc
     9961 taagatagat tttggctgtc tgtaaaaact gacgatagat ccggttggtc aaatgacgag
    10021 tcaacgcagg caggaatgtc gcacttaatg cagtggcaat cactaaacct aattgtacta
    10081 aaggctgacc tcgatcatag accccttttg ctatcttcgc accgtattct gacagtccgt
    10141 aaacttccaa agcatttttt acaaagaaag agtcgatcag ctggaaaaag ataagcaatc
    10201 cactataaat cgaaaccagt ccgccttcta ccagaaaacg ccggatcaag ggctttgacg
    10261 gctgtttgaa caatggaaac cgtcggaagc ttaacgctcc tccatgaatc ttttgttcat
    10321 agtagtgaag gatcccatat gcgcataaac cgccaaaaac agctccactc attgctgccg
    10381 tccctgtttg gtacaccgtc catccaagct ttctaaaagc aaacgcacta cagacaatca
    10441 caaaaacacg aacgaactgc tcaactactt gagaaacagc agttggttcc atcaagaatc
    10501 ttccttggaa attccctcga taaaaagata gaccaggcat cagcaaaaag gtaaaggaaa
    10561 ctacttggat cagcggtttc aattgtatgt ctcccatcat ccaagcaatc cagctgctaa
    10621 atgcaaagac aaacaaccac aaaaagacac ctgtccaaaa tactaaggga taaagatttt
    10681 gcaaagcttg ctttcgctcg aaaggattct ttctttctgc aacgtacttt gatatgaact
    10741 gcggaagacc ggataaagct aaagtcattg ctatcccata aattggataa acttgctgat
    10801 aaacataaaa accttcgtcg ccgactaagt tttggagggg aattcggtaa agggcactta
    10861 atacttttgc tatgaaagaa gcaatcgtca atacaaatgc tccttgcatg acgcgccgca
    10921 tttctttatg atccaaatca ttgctccttc ctacgctgac agatattttt gctcacgcaa
    10981 cgctttgaca aacttttgga tttcctgaag ccatactgct tcttccattt ggttggggat
    11041 cgtcaagcgt atcaccatct gttctttttc aacgcctaga ctggctttta gttttgtcgc
    11101 tgtcagtgct tcgaataact gttccacact atagcgtttt gttccaactt tacttagagt
    11161 aaagactata tgcgcctcct gtttccttat cgtttctagg agcgctcgat cgccatccat
    11221 tttgatctgc ccaattgtca agagatgtgc tacttcttct ggatattctc caaaacggtc
    11281 gagcagatca tcttctagtt catctagcat ttcttgcgaa tcaagttcac gaattcgttt
    11341 atagatctcg attttctgcc gttgatctgc cacgtatgtt tcaggtagat acgcatcgac
    11401 accgaggtcg atctcaacag tggtcttctc cacttgacta ttctttcctt gtttacgaga
    11461 aacagcttcg cttagcattt gagaatacat atcgaaaccg actgcatcaa taaatccatg
    11521 ctgctgagca cctaagagat tacctgcacc gcgaatggaa agatcccgca tcgcaatctt
    11581 gaatccagat cccagttctg taaaatcttt gattgcctga agacgttttt cactgacttc
    11641 gttaaggatc ttctgctgct catacataaa gtaagcatat gcgacacggc tgcttcttcc
    11701 tacccgccct cgcaattggt ataacgtgga taatcccata taatcagcgt tctcaacgaa
    11761 caacgtattt gcgttcggga tatctactcc tgtttcaatg atggttgtag tgacaagaac
    11821 atcatattga ccttcaataa attcaaaaag cgtattttct aattgcgcct ctgtcatttg
    11881 cccatgagca taaccgatcc gtgcttccgg aacgagttct tggatttctt ctactttttg
    11941 ttcgatcgtt tctacccgat tatataaata gaatacttgt ccacctcgtc ccatttctcg
    12001 atggattgct tcgcgaatag ccccaggatt tttttccata acatacgttt ggatcggata
    12061 acgattcgca ggcggtgttt cgattactga aagatcccgc acgcctaaca tcgacatatg
    12121 caaagttctc ggaatcggtg ttgcagtcag agtcaaaaca tccacttgtg cacgtaactg
    12181 tttcaatcgt tccttatgtt ttacaccaaa acgttgttct tcgtcaatga tcagtagacc
    12241 caaatcgcta aattcaatat cttttgacaa aattcggtgg gttcctacaa caatatcaac
    12301 ttgacctgta cgcagttgtt cgatggtttc tttttgttgc tttcttgttc tgaaacgact
    12361 taatagcccg atatttacgg ggaaaccttc aaatctttcc agcatcgttt catagtgctg
    12421 ctgtgccaag atcgttgttg gaactaaaaa ggctacttgt ttgctttcct ttatcgcttt
    12481 aaaggccgct cgaagcgcta cttctgtttt cccataacca acatcaccta cgagtagtcg
    12541 atccattggt ttttcttttt ccatatcccg tttgatctcc gctgcacttc tcaactggtc
    12601 atcagtttca gagtagggga aggcattttc gaattctttt tggtaggcgt catcaggtcc
    12661 aaaagcatat cctttttctg actctcttgc ggcatataat ttgattagat cgtcagcgat
    12721 atcctcgatt tttgaagaga cttttcgctt ggttttcgtc cattcacttc cgcctagctt
    12781 attgatgcga ggcgctttgg cttcagaggc gacatatttt tggatcagat tcagttgagt
    12841 aacaggaata aacagtttgt cgtcgttttg atacaaaata gtcatatagt cttggtgaac
    12901 gccatctact tctagcgttt ccatcccaat gtatttcccg ataccatgat tggcatggac
    12961 aacgtaatct cctgctttta actcattata gcttttcaat cgctctgcgt ttgttactgt
    13021 ttgacgtctc gtttgttttt tcgtcgtttt ttggaaaatt tctttttctg tgatagctac
    13081 tattttttct tgaggaagtt caaaaccagc ctgcaaagct ccttcaacta attgtacctg
    13141 tcctctgatc aatgcatttt tttctgtttc tactactaat atgtcttcat ctcgaagcat
    13201 ttgttctgct ttgcgtattc tgtcctttgt cggaataaag atcacaacag tctgtttttg
    13261 cttgcgccaa cggtccattt ctgttttcag caatggcatt tgtccgaaga actgttgcat
    13321 cgtccgatat tgaaaattat ggattgcttg gaaacgaaga tttcccatcc ctttttggaa
    13381 gagtgagaaa aaggttgtgg tgaacttttc cttctgcacg attttttgta tatctgctga
    13441 aaatgtctgc tcagaaaaca cccgcaattc gctgattttt tgagtctgcc attctgccgc
    13501 ttccctttcg atttcccgat ttgtttccat gattcgctga taatcatcaa cgactagtaa
    13561 actatttgaa gggaaataat ccaagatcgt cacagattct tggtaaagaa gatctgagta
    13621 gaattttgct tcttctgtcg ggacacctgc ttgccagctt gaagtcagct gaccgaagta
    13681 atcttgcaaa aactcgcggt ctgcttcttc tgtggtcgca gcaagccgtt tttctagcat
    13741 tttttgcatt tgctctattc catgttctag atcctctggt ccgtagactt gttcactcgt
    13801 tggggaaacc cagatttctt ccgttttttc gattgagcgt tgtgtttctg cttcaaaata
    13861 ccgcatagaa tctatctcta catcaaatag ttctacacga acaggatagg ttgtcgttaa
    13921 cgggtaaata tcgataatgc ttcctcgaat actgaattct cccggttttg cgaccatctc
    13981 ttctcgtaca tagcccatca aagtcaattg gcgaggaaga ttttccacgt ctatctcatc
    14041 accaatatgc caattcaatt gcgcctgtag ccaagttttc ttattcggca gtcgtttgtg
    14101 caaagatgcg actggcaaca aatagatacc tgcttttttt tcttgaagtg cgttaagcgt
    14161 tgcaactctc tcgcctcgcg cttctggaga agaaaaggcc atttcagcag aaagcacttc
    14221 atccactgga aataaatgga tctgatcttg cggaatcaca tgttgcagat cttctgctaa
    14281 ctgattcgca taatacaaat ttggcatcag aataatcatg tttttatttg ttttcttaaa
    14341 cgctcgagca aatagaagtg ttttcgctga gcccgctaat cctgtgatta gttgtctagg
    14401 cattttttct tctaaattgc tgacccattc ttttacttgc ggatcttttc cgactaattg
    14461 aataatatcc attccttttc ctccttcctc aattgaatcg attcatcgca tccacgaacg
    14521 aatgcccttc tatgagatat tcgactgctt taacagattg acacatgctt tcttctatca
    14581 aaggctgatt ttctttgctg aaaggactaa gcacatgctg gactactgtt tttttccctt
    14641 ctggcctgcc gattcccacc ttgattcgat caaagacatt cgtattcaaa tgggaaataa
    14701 tacttttgat accgttatgc ccgccggcac ttcccttttg acggagccgg atttttccca
    14761 ctgccagatc caaatcatcg tagattacga ctaattcctc tggataaatc ccaaaataag
    14821 tcattagtgg gccgactgca cgaccagatt cattcatgaa tgtttgtggt ttgactaaaa
    14881 ggatcttttc tccattatga aaaaattcgg caacttctgc ttcgaacgga ttttttttga
    14941 aagtagcttg atgctcgcgt gcaattttat ccacgaccat aaagccgata ttgtgttttg
    15001 tatattggta tttggtacct gggtttccta acccgacgat cattttcatt tttgttttcc
    15061 acctaattct aaaaagcagc acaaaaggct ggactgctaa ttagcggtcc agtccatcga
    15121 gcttttttct tttttatact tgtcaatgca tagtataaca caaaacaagg cgtttcggct
    15181 aaaagagaat cgttaataaa tgataaagaa attaaaaatt tcttcaaagt ttaatgaaat
    15241 aattgatata taaaaatagt gaaataacgc acatgtaagc ttttacatat aatacaacct
    15301 tgttatctgt tatattttat agccaaatag cgtgacatgg ggcttgagaa atgttagcat
    15361 aagcatggga aaaaacaaat caatggaagg attgatacta aatgactgca gctgcagaaa
    15421 aaaaagatca tcaaaaagtt attcttgttg gagacggcgc cgtaggttct agctatgcct
    15481 ttgctctagt tactcaaaat atcgctcaag aagtaggtat tgtggatatc aatactgcta
    15541 aaactgaagg agacgcaatt gacttgtctc acgctttggc atttacttca cctaaaaaaa
    15601 tctattctgc tacttacgca gacgcacatg atgctgactt agttgttatt acagctggcg
    15661 caccacaaaa accaggtgaa actcgtttag acttagtaaa caaaaaccta aaaatcaacc
    15721 gcgatgttgt cacacaaatc gttgaatcag gatttaacgg tatcttttta gttgccgcta
    15781 acccagtaga tattttgact tactcaactt ggaaattctc aggtttccct aaagaacgcg
    15841 taatcggttc aggtacctct cttgactcag ctcgtttccg tcaagcactt gcggaattag
    15901 ttgacgttga tgcacgtaac gtccatgctt acatcttagg tgaacacgga gattcagaat
    15961 tcccagtttg gtcacatgca aatgttgccg gcttgcaaat ctatgaatgg gtaaaaaaca
    16021 acccagaaat cgatgaagaa gctatggtta acctattctt tggcgtacgt gacgctgctt
    16081 acacaattat cgagaaaaaa ggcgctactt tctatggtat cgcagtagca ttagcacgta
    16141 tcactcgtgc catcttagat gatgaaaatg ctgttcttcc tttatcagta ttcatgaatg
    16201 gcgaatatgg attgaacgac atctacattg gtgcacctgc tgttatcaac cgtcaaggta
    16261 tccaaaaagt aatcgaaatt cctttaagtg acagcgagca agaccgtatg gctgcttctg
    16321 ctaagcaatt aaaagaaatt ctagatgaag cttttgctaa actagacgct gaataatctt
    16381 tgaacatgac ggaaaacatc tattcggtgt tttccgtttt tttattttat cacccttatg
    16441 gtttctaaat tttttcataa agtagagata accttcgtct tttcctctaa attatgctat
    16501 catgagaccg ttccacccta aacttttact taaggagttg tcgatatgac aagatcttcg
    16561 catcgaaaaa aatcgaaaca tgttgctttg ctttcagttc ttggtgttct cttagtgctg
    16621 atcagctttt atacctatcg cagtacatac tacacaaagc attttttgcc gaatacagaa
    16681 ataaatggaa taaatgtcag caatctaaca gtcgaaaaag caaatgaaaa attaaaagaa
    16741 gcttattctg ataaaaaact ggctattaaa gaagatggaa aagtctggca ggaagtacca
    16801 aaatccgagc tcggctacaa agatgatttc acttcggagc tttctccgat cctaaatgaa
    16861 caaaacggat ggacttgggg aatgacttat gtctcagcgg cagaaaaaca agaaatagat
    16921 cctgtcagtc aaaaccacca aaaactagac actaccgttc agacattgac aactaagctg
    16981 actgatttga acaaagaccg gacacctact actgatgcaa cgatcgaaaa agcaggtgac
    17041 tctttcgtta tcaagcctga agtcaatgga aatacgatcg acgtcgatgc tgcggtcaaa
    17101 caattaaaaa gtgcggtaaa ctctggtaaa gatacaattg aattgactga attcaaagaa
    17161 aaaccaaaag taacatctga agacagctca ctgaaagaac aactcgcatc catgaatgct
    17221 atcgcaaatg taaaagctac ttacagtata aacggtgaga ctttccagat cccatcaagt
    17281 gatattatga gttggctgac ctacaatgat ggaaaagtcg atttagatac agaacaagta
    17341 cgtcaatatg taacagattt aggcacaaag tataacacaa gtacgaatga cacaaaattt
    17401 aaaagtacaa aaagaggaga agttacggtc ccagttggca cttacagttg gacgatccaa
    17461 acagacagtg agacagaagc attgaaaaaa gcgattctgg caggccaaga ttttactcgt
    17521 tcacccattg tgcaaggtgg cacaaccgct gatcatccat tgatcgaaga tacgtatatc
    17581 gaagttgatc tggagaacca gcatatgtgg tattacaaag acggaaaagt ggcccttgaa
    17641 acagatatcg tttccggaaa gccaactaca cctacacctg ctggagtctt ctatgtttgg
    17701 aataaagaag aagatgcaac tttaaaagga acaaatgacg atggaacacc ttacgagagt
    17761 ccggtaaact actggatgcc gattgactgg acaggtgttg gtatccacga ttcagactgg
    17821 caacctgaat acggtggaga cttatggaaa acccgcggtt cacacggctg catcaacacc
    17881 ccaccaagtg taatgaagga attattcggg atggtcgaaa aaggaacgcc tgtattggtc
    17941 ttctaacaaa aataatatat aaaaagaaag cacccgtacg attggtacag gtgctttctt
    18001 tttattatct aacaatgtgc tacttacatt tcagcagcag taaagacttc tgaaacatca
    18061 tcatcgtctt ctagcttatc tactagacgt tccaattgct ctttttgttc ctcatttaaa
    18121 tcaatcgtcg tttgtggaat catcgtcaat tctgcttgcg ccaaagtgaa ctctttttcc
    18181 aactcatctc gtacagcagc aaaatcttct ggtgcagtat aaatctcgaa tacttcagga
    18241 gaagtttgca gatcttctgc ccccgcctct aatacatcct caaacatcgt ctcttcatca
    18301 acagtcaacc catcgcgttc aatagcgata tatcctttgc ggtcaaacaa gtaactgact
    18361 gaacccgttt ctcccagtga tccaccgttt cgagtaaaag ctactcggac atttgtcgct
    18421 gtccgattac ggttatctgt caatgcatgg actaagattc ctactccacc cggaccatat
    18481 ccttcatacg tgatttcatc gtaattcgtt tcatctacgg cactcgtagc ctttttaatc
    18541 gcccgttcca cattgtcgtt aggcatattt gcagcttttg ctttgtccac aacaagccgc
    18601 aaagctggat tcatagatgg atcaggaccg cctgctttag ctgccatata aatttcacga
    18661 gaaagtttct gaaagacttt ccctcgtttt gcatcttggg cattttttct tccttggata
    18721 ttatgccatt tactatgtcc tgacatgatt tttcctccct tgttcttttg agaatacact
    18781 tctattctag tactatttca caaaaaaaca aagccacagc caatctataa acgcttcttg
    18841 aatgccgcaa aaagcacaca taatatcaca gcagtcagag caccgatcga atccaacatg
    18901 acatcttgga acataggtgt tcgtccaccg gtcatcatct gatggaattc gtccaaacct
    18961 gcgtaccctg ttgctgaaag ccaagcaagg atcgctgtca gccaccaaat ttttagcttg
    19021 gggaaaacac ctaaaaacaa gctgcctccc aaaataaaat aggtaccgaa atgtgcgccc
    19081 ttccttaaaa agaactctaa aaatttggcg tagcccagat ggtcgatact caccatactt
    19141 ccaccataat taaaacgtat acccgctaat gtgtctttaa atggctgatt aggcagccag
    19201 ctttctaatc gcgaaacttg tgattgctgt ccgtaagttt gagaagaact gtaaaataag
    19261 attataacga ctatcagtgc gattactaaa taaatatttc cgtttttcat ttgttttttt
    19321 gaagaattca taagtcacct ctgtatttta tcttagactt tttttgaaga aacaacaatc
    19381 attttcatag agacttcttc cataaaaaag tgctatactt aattttgtat tacaatatga
    19441 agggagtttt ttcatgagtt attcattaaa ttggaatcta gattctattt tttccggagg
    19501 cagtcattct gatgctttga accaacggat gaagcaattg gaagaccaaa tgaacgagta
    19561 ttatcaccgc gtaacaaaat ggtcacctag ttctgacaat gcagagcagt taaacgctat
    19621 tcttcaattg caagaaacga ttacgaatgg ttttacccaa tgcagcagct atattactgc
    19681 attgctttct gccaatgtca atgattcaga tgcaaaggtc ttatcaggca agctttacgc
    19741 aatgctgcct cgtctgcaat cagccgaaac tgtattgtca aagaaatttg cagaaatatc
    19801 tgacaatgat tggaatcaga tgctttctca atcttcgttt gaaacaattg cttttcgttt
    19861 aaacgagatt cgtcgtgatg gctcacaatt attatcagaa gctgaagaaa acattataaa
    19921 tacgctttct ttagatggtc taaatgcttg gagcagtcat tatgatacga ttgtagccag
    19981 catttcgatt cccttcgaac aagatggaca agtagtcgaa ttatctgctg gacaagcctt
    20041 caataagatg atgggcgatc cagatccaaa agtcagagaa acacttttcg cagcatggga
    20101 agaagcctgg aaagaaaagg cacccctctt cacggatact ttgaatcatt tagatggttt
    20161 tagactttct gactatgaac ttcatggtgt cacagatttt ctacaaaaac cattagagta
    20221 caatcggttg aagaaagaaa cattgtctgt catgtgggat acaatccaga aaaacaaaca
    20281 accccttgtt aattacttga ctagaaaagc taatcttttc ggtaaagaaa aaatggaatg
    20341 gcaagatcaa gatgcaccta ttattttagg cgatttgaaa gaaaaaacct ttagttttga
    20401 cgaagcagca gcatttatta tcgaaaactt taacaaattc agtccaaaaa tggctaaatt
    20461 tgcccaatct gcttttgaaa agagctggat cgaagcagaa gatcgtcctg ggaaacgtcc
    20521 tggtggttat tgtactgagt taccagaaac aaaagaatca aggatcttta tgacctacag
    20581 taattctgtt aatgaggttg cgacacttgc tcatgaacta ggacatgctt tccatagcag
    20641 cacgatgtgg gatttacctt ctttaaatcg cgaatatgcc atgaatgtcg cagaaacagc
    20701 aagtacattc gcagaactga tcgtagccga tgctacatta aaagtcgcaa aaacaaaaga
    20761 agaaaaaatc aatttgctag atacaaaact gcaaaatgct ttagctatgt tcatgaatat
    20821 ccattcccga ttcatttttg aaaatcgatt ctatgaagca cggcaagaag gattagtctc
    20881 agaagataag atcacagaga tgatggttga ggcgcaaaaa gaaggctatc aaggagcttt
    20941 agctacttac catccatatt tctgggctgc aaaattgcat ttctttattg atgacgtacc
    21001 gttttataac ttcccataca catttggcta cctctttagt ttgggcatct atgcttacgc
    21061 caaccaaaag ggagcaaatt ttgaagaaga atatatccat ttactacgcg atactgcctc
    21121 aatgacgacg gaagatcttg cgaagaaaca tttgaatgtc gatcttaccc aaccagattt
    21181 ttggcaagca ggtatcgaca tggtgactga agatatccaa acgttcatgg aattgacaga
    21241 agaatttatc tgatttctat tttatcacaa taaaaaaaga gttagtccag aatgggctaa
    21301 ctctttttga ttaatcattc ttacatgctg acagcaaagt caggggcaaa ccattgaact
    21361 gaaccaactt ttacgctttc gcctggttga ggagcatgga tatattgtcc tccgcctaaa
    21421 gcaatcgcta cgtggtaagt tccgccttgt gacccccaga ataacaagtc tccagctttt
    21481 gcttgagaaa ctgaaatttt tgttccagct gattcttgag gaactgtcca accaccgatg
    21541 tcacgaccag ttacttgcat gtaaacatag cgtgtgaacc ctgagcagtc aaagccactt
    21601 ggatctttac cgccccaaac atatggagta ccaatatatt tgtaagcttc tgctacgatt
    21661 gctgcaccat tcacacttcc agaaggagct ggagcaggtg ttacaggttt tggttgttca
    21721 ggtgttggtg ttggcgttgg agccggagta ctacttcctg tgccgtttcc tgtatcaaca
    21781 ctttgatctg ttgatggtgt tgtaggcgca ggtgttgttg attcttctgt tgttgaagat
    21841 tcaggcactg ttgttgattc ttctgttgct gaagattcag gcactgttgt tgattcttct
    21901 gttgctgaag attcaggcgc tgttgttgat tcttctgttg ctgaagattc aggcgctgtt
    21961 gattcttctg ttgaagattc aggtgttgtt gattcttctg ttgctgaaga ttgtgtagct
    22021 gatgatgatt cttcagtcat tgaagattgt gtagctgatg attcttctgt tgctgagctt
    22081 tgtgcagtag atgaagcttg agtagcttgt gcttcagcct ctgcttgttc gcgtgcttct
    22141 ttttcagctt tttcttgtgc agcttgttga cgagcttgtt ctgctagacg ttgttgttca
    22201 cgaatacgag cttgctctgc ttcagcttct gctttttgac ggttcaagtc agctttcttg
    22261 tcttcagcag ttgcttgttc agcagctaat gaagttttca gtacgttcaa atcagcttgt
    22321 ttagataaaa gatcgccttt ttgagattcc aaagcagctt ggttttcagc taattctttt
    22381 agtttagcat cgttttcagc ttttttgtct tctacagctt ttttatcttg tttttgttgt
    22441 tccatcaagt cgttgtttgc ttttaccatc gttgtcattg cttgaacgcg tccaatagca
    22501 tctgctaatg aatcagcatt caatacagca tcgatgtagt ttgagcttgt gttgcttact
    22561 tgtgcttcgc gtgcttgttt ttggattgta tcttcacgtt tttcaatacg ttcttgtaaa
    22621 tctgcaatgt cttttactaa ttgtgcagat tcttgacgca atgtatcttg ttttgctaat
    22681 aggtcttgtg cttgtgtgtt gatttcagaa acttggcttt ctaaggcatc gatttgtgat
    22741 tgtgcatctg cttgttgatt tttcaagtct gcaatctttt gatcttgctg ttgtatctga
    22801 gaatcaaaat cgtccgccgc ggcagcgatc ggtgatgcta cggcagtcaa ggtcattgaa
    22861 cataccatta ctgctgatat taaactcttt ttcactcttc attcctccga ctggcttaat
    22921 ttaataaata tctaaatata tttaagtctt tcttaacgat ataaaaattg taccatagca
    22981 gtgtgtcaac gatataatag ttatgttaca aaaatgtttc aaaacaactt ttaaaaatga
    23041 caaaactgtt cgtttcagaa aatgatcatg aaaaagccgc gttaagtcta gcatttctta
    23101 agataacaac gattcttttt cgctttcgac ctaaaaataa aaaaagaaat tattcatcac
    23161 tgaataattt cttaaaggga aaaatgaata atacaaatat aatcatgttc aacagcagtg
    23221 taggtcctaa aaaccttgta ataaaatacg tgttatttac tactgctaat ttaaaaatca
    23281 actggaccac catcgtaaac aattcataac ccgtgacaaa gatgatcata ctgaaaaatt
    23341 cagtaaagat gttgacatgg ataacgtctt tcattacata catcaaccat acaattaaag
    23401 ggagagctac tgcatagata ccgataacgc caatatagta agcgtcatag atagccccga
    23461 gaacaatcgt ggtaatcagt aaataacgtt tttcaaacgc catactgcaa cataataatg
    23521 ccaatatcag aaagtgggca tttgacatat aggtgccttt cgaccactcc cctagcattc
    23581 ttgttaaatg accatctatc aacatcaaaa agaacaaaac gattggcaga tagtacttca
    23641 ttgtttcttt cttcaacatg gactaatcct ccgctagccg ttggacaatc gtcacaactg
    23701 acacgtcata catttctgca taaggtttca cataaacttc ccgatccagc ccataactat
    23761 ctggtttcgt tttaataacc gtaccgatcg gcaagttagc tggagaattc cctccaagac
    23821 cggatgtctg gacaacatcc ccttctttga tatccgtatc accagttaat tgggtcacca
    23881 ctaaggcatg gagcttttca tcatagtttt taagcaaacc aaacgcttcg ccattagccg
    23941 aagatacccg tactggaaaa tgattggagc tttcattaga ggatgacagt aattcgattt
    24001 tagacgaagc cgtattgacc tcgatcactc ggccaatcaa tcctttttgc gacatgactg
    24061 ccatatttgc ttcgataccg tctttagaac ccttgtctac gatcagcatg tcctgccaac
    24121 tgtcaggcga acgagtaatg acatttgccg ttactttttc gtaactagtc agcgtctgat
    24181 tcaactcaag ttcttttttc aacgcttcga tttctctctc gtaattcttg ttttgctgtg
    24241 aaacgtcatc atagctatcg attttttctt ttagccgctc attttcggca taagttgaaa
    24301 aaagattatg gacagaatct actccatttc gtacccaccg tactggggca gagattgttt
    24361 tatcaaccat tgcaacactg tcattaacga tggattggaa gaaattgggc tttccttcat
    24421 tcgctcgctg cgcagcggtc acacttagta tcgtcaccac gatgataaca ataaccaagg
    24481 taataataat atttttatta ggattgaact tcttcacaaa gacacctcga attaattaga
    24541 ctcttgtgtt caattttatc actaaatgcc gtgaaacaaa aggtaagttg ctcctcttaa
    24601 gctttttttt agcaaataat agattctgtc atttttagcc tgaaagacaa atttttttat
    24661 ttgtttatgg atcaatcttt gctttgaata actgcaatca taccatctga aaaagaaaat
    24721 tctgcggtat ctgaaagaaa ttcgttactt gcataagatg tcggatattc tacttcttta
    24781 ttttccaata catacttgct gccttttaat gtaagattcg agacgggagt caagcagcaa
    24841 taagctaaat acttcatatc tggtatctgt cttactatat gctctccagg caaataataa
    24901 gacaaataat tttgacaatc tctgataata agctgatggg caaagggttt gaagcgaggt
    24961 tccataccta accagagatt ggctaaaaga tgatccaatc ttccgcccgt agctccaatc
    25021 aaagtgactt ccgcttgcgg gtaacgttca aatgttttta agatacctaa ctgtgtatct
    25081 gtatcgtctt tttctgcagg ggaacgggta tactctttgg cttttgcaaa tacttccttc
    25141 tgctcttcgt tcgacaatga atcaaaatcg cccactgcca gatctactgg gtagcctgct
    25201 tgaagcaggt acagcgcacc acggtctatc ccgacatagg catcgtattt ggacagcaga
    25261 gactgcggcc agttttgcgg attacctcca gcagctaata aaattttcat ttagtctaat
    25321 gcctctttta atcgttcgat ttgtccgact ggattttcgg ctccatagat atatgatcct
    25381 gcaacgaaga catccgcccc tgcatcttta cagatttttg ctgtttctgg aacgattccg
    25441 ccatctactt cgattgcata agtccaattg ttctctctac gtagatcagc gagttccgta
    25501 attttttcta ctgtttcttc aataaagctt tgtccgccga acccaggatt gacagtcatg
    25561 actagtactt gatcagccaa aggcaaaaca tgtttgatca tggagactgg tgttcctgga
    25621 ttgataacta ctccagcttt aactcctaag ctttttgtca tttgaagtgc ccgatgaata
    25681 tgaggagttg cttcgacgtg gacagtaatg atatctgctc cagcttttgc aaatgctgga
    25741 atgtagtttt ctggatcaac gatcatcaga tggacgtcta acggtaattt agtaacagga
    25801 cggattgcct gaacaatatt tggccctaat gtgatatttg ggacaaattg gccatccatt
    25861 acatctacgt ggatgtaatc tgcgcctcct ttttccacta actcaatgtc tctttgtaaa
    25921 ttggcaaaat ctgcactcaa aatggatggt gctatcttca ttcttgtttc ctcctatttt
    25981 cgtttacctt ctttttttgc atacattggt tttctttttt cgatttcttg taagaattgc
    26041 aaataattgt cgtaacgtgt ctgtgcgata ccacctgttt ctactctatg ttttacttcg
    26101 cagccaggtt ctttagcatg catgcactct ctaaatttgc aatggacaga agcttctaca
    26161 aattcaggaa attgtctcgg cagttctcct gcttcaattg tcaaaaagtc aatcgagcta
    26221 aatcctggtg tatctgctac taacccgcca tagataggaa tcagttccac atgacgtgtt
    26281 gtatgccgtc ctcttccaag tgcatcagaa atctctcctg ttgctaaatt cagttccggt
    26341 gatatttgat tcagtagcgt cgattttcct gctccagact gacccataaa gaccgatagc
    26401 cgttctggga agtaacggat cagttctgtc gtatcacccg tatgattggg tacaatcacc
    26461 ggatagccta ttttagtata ggtttgcttg atctcttcga ttttttctgg gtcgtctgac
    26521 aagtcggtct ttgtcaaaaa aataatcggt tcgatcgact cgtattccaa ggtaactaga
    26581 aagcggtcaa gtagattata agaaaatgca ggctctacga tacttgtgac aatgattcca
    26641 agatcaacat ttgtgactgg tgggcgaact aattgatttt ttctcggcaa gatttccaga
    26701 agatagccgt ctgtttgatt ttcactctca aagatcacct gatctccgac aagcggcgtg
    26761 attttccgat tccggaaatt tcctcttcct cttgtttgat aggtctctcc gtttgcgtat
    26821 acatagtaaa aaccgctgat tgcttttctg atttgtcctt tgataagtgc cacctccgtt
    26881 tttgtttatt ttaccatacg aagaggaaag taggtgttat tccatgcaaa cttctcaaag
    26941 tatatggctt gaaaattgat caaaagagat agaaacacaa aaaagagaat gcaacaaatc
    27001 aatgtcgcat tcccttctga tatattttat tcagcactta ttttgaactt tctgaggtgc
    27061 tagctgatga acttgtggag ctggaagatt cttcttttga agagttgctt gtgctactgg
    27121 agctacttga gctgctagaa ctgtctgaag agtctttttc agaactagaa gacgctggat
    27181 ctggtccttt agagtaaatt acgttcacaa ccattccttt ggtaattgtc gttcctgccc
    27241 ctggtactgt acgaatcact ttatctttat ccaccgtgtt tgaatattcg gaagtctcat
    27301 gcccgatata ttctgcaccg acactagcta aataactttg tgcttcgctt tttgtatagc
    27361 cggagatatc attcaattta ggctctgttc cttggcttac gacaaaattg atgtaagttt
    27421 cttctgctac aacttcaccc gaggctggat cctgactgat gatcgaacct gatggtacag
    27481 tgtcgctata gtcataagta gcactaatat tattgatatt gaatccttgt gtaacaagcc
    27541 aattacgaac agtttcgtag ttttctccta catgactact caaagtcact gtttctggtc
    27601 ctttgctgac tgtgaaagta atcgtgtctg ttttaggatc gacttctgta tcttctgatg
    27661 gagattgcga aatgatcatt ccgctttcta cctctgaact gaattcctct tctttttgaa
    27721 tcaagtcagc agaaaaccct aattctttca aacttgcttc ggcatcttca taacttttac
    27781 cactgtaatc atctaatttg atttttttcg tgccgctact aatatacaga gtgacttcgc
    27841 gtttttgctt gactgtcgtt cccgctgccg ggtctgtctt cactacatta ccttcttcga
    27901 ttttgtcatc tgcaatttct tctgtttttg ttgctacttc taatttcgct tttgcgagtg
    27961 tttctctagc agaagcttca gaaagatcag aaacatcagg aacaacaact tctcctcgcc
    28021 cgccagaagc aaagaataca gctgttccga ttcctaaaac agcaagaata gctaatagga
    28081 tcagccacca ttttttctgt cctttctttt taggatcagg cagaacttct tcctcctctg
    28141 gcaaggtttc gttttctggc ttgtcttttg gcagaggcat agatttgaat gaatcaggca
    28201 ttggtgcatc ttccgtaagg ggtgtgataa cttttgtttc attatccatc acatgaggct
    28261 gccatttttc ttcgtttgca cgagctggtg ataatactgt agaaagatca tcagacattt
    28321 cctcggctga cttataacgg tctgcaggtt ctttagccgt tgcccgtaaa atcacgtttt
    28381 ccagtgcttg tggcacattt ggatcaagtg cttttataga tggaagatca tcttgaaaat
    28441 gttttaaagc aattgttaca gcagattcac catcaaacgg tacgctaccc gtcaacatct
    28501 cataaaggat gatccctaaa gcataaatat ctgactgctt cgttgccata cttcctctgg
    28561 cctgctcagg ggacagataa tgaacagatc ccagcatcgt attcgtctgc gtgatcgatg
    28621 tttcagataa agcgatagca atcccgaaat ccgtgatttt tacaacacct tcattatcga
    28681 tcagtacgtt ttggggtttc aaatctcggt ggatgatttg atggttatga gctaaagaaa
    28741 tagcagaaag gatctgctgc ataatattta ctgctgtttc ataaggaaca ggataatgtg
    28801 tttggatata tcgtttcaag tccattcctt tgacgtattc catcaccaga tactgcatgt
    28861 tgtcttcttc accaacatcg taaacactaa caatgtttgg atgaacgagt tctgttgctg
    28921 ctaaagcttc tctctgaaat cgtcgaatcg cagtctggtc attttgaaag tcaaatcgta
    28981 agactttaac tgctacatca cgatccaaga ttaaatcgtg cgccaaaaat acatttgcca
    29041 taccaccgct accgatattt ccagtgattt gataacggcc atttaatttt ttgcccaact
    29101 cgatcataca ctgtcctcct tatattcgat aagaagaacg gtgatattat ccgctccgcc
    29161 tgcttcattg gcacgatcaa tcagctcagt tactttatga gacaatgggc cttcttgatt
    29221 gatgatcgtt cctatttctt cttcagacag catgttcgtc aagccatctg aacataacag
    29281 cagtcgatct tttagttgcc aaagatgagt agaaacatct acttcgactg ttccaggcat
    29341 gccgacagaa cgtgttaaaa tatttttcct tggatggttc actgccattt cttcgctgat
    29401 ttctcctgat ttgactagtt cattgactaa agaatgatcc tccgtcaatt gcatgatttt
    29461 atcttcacga atcaaataag ctctgctatc cccaacattg gcaatcgtga accagtcatc
    29521 tgacagagcg gccgctacga ttgttgttcc cataccgtta tattccggct gttcttgtcc
    29581 acgctgataa atcagcatat tttcttcttg aatcgattga atgaaccatt gggcgatttt
    29641 ttcatcgtca acagcttctt gtttttccca agcttcgcct agattcgtta ccgccatctg
    29701 actggcaatg tctccggcac gatgaccacc catcccgtct gctaatacag caagcttgag
    29761 acctgaacgg ctggtaaata cactggcata gtcttgattt gtgttacgtc gtcttcctac
    29821 atctgattga tattcaatct gcattttttc acctcattac tttttgcgca aacaacaaat
    29881 gaaaaatcca tctgtgtaaa actgatgcgg atacaaagtc aacattttct cttcgattga
    29941 tgattgtagc ataggattgg tcaaaacatc aatcctctca aaatcagggt gtctttccaa
    30001 gaaagcagaa acaacgtctt ggttttcttc ttttaagatc gtacaagtgc tataagtcag
    30061 aataccggaa gactttaaag ttggtgcgca gctttctaaa atttccaatt ggatttttgg
    30121 taaattcgct aattcatccg gctgtttttt ataacgaata tctggttttc gccgaagcag
    30181 cccaagacct gaacaaggcg cgtctactaa aatccgatca aactgctctg cttcgaactg
    30241 tttactgact tctctagcat ccatcttttg agcgtagaca gcagaagaga cacctagacg
    30301 tgctgcatta tcttcaatga gtttgacttt gtgttcgtgt acatctaaag cgaccacttc
    30361 tccaccgcat gacggatcta aaaaagaagc aatatgcgtc gtcttacctc cgggtgctgc
    30421 acaggcatct aagacatgat gttcaggctc gatttgcata gacggcgcta caagcatcga
    30481 actttcatct tggatcgtca tgacgccatc gtggaacaat gagctagaag ctaaatgccc
    30541 ttttttcgct actataccgt atggactgac ttggcttttt tcagctgtga tctcttcttc
    30601 ttgcaaaaca gtgatggcct gatctctgga aagtcggcgt gtatctactc gggcactagc
    30661 atggctaggc tgatatagcg ataaaccgag cttttcagtt tcttcgtatc cgatttgatc
    30721 caccagtcgt ttcgtcatcc atagaggcag gctgattttg acagaaagtc tttcgatagg
    30781 atcagcaatg ccttgcagat ctggtgctcc ttgacgctga taattcctca agacaccatt
    30841 tacaaatttc cctgtcccag gatttccttt tacttttgcg atttcgaccg cctcgtttaa
    30901 aatagcatgt gcagggactt tatctaaaaa ttctaattgg tatacagaaa gataaagaag
    30961 cgtcttgacc cagtcatcca ctttttttgc tttagcgatc aatggtgcaa cgtaaaattc
    31021 caatagtcgc tgatggctaa tcgtaccata gatcaattct gtaaataaac ccacatcttt
    31081 ttgatttagc tcgctttgtt tgatcatctc attcaacaaa agattcgagt aggcgccacc
    31141 cttgttcact cgctctaatg tcagtaatgc catatatcgt actgattttt tcattttttt
    31201 agggattttt ttcattattt cacctgctga ccaatctgaa cttgctgacc gcttccgtta
    31261 aggaaatcat gtacggcctg ttttccttta ccagctggct gtaattcatt gatggctaag
    31321 acggtctgtt taccgcaagc aatccataga ttttttttgt ctttccggat gatcgtacca
    31381 ggtgctttgt ctgtagtttc tgccaatact tcaaccgata ataatttcca gcgtatgccc
    31441 tcataggtcg tgaatgcaat tggccaagga cgcattccgc gtacttggtt gtcaatttct
    31501 tctgcagttt tatgccaatc gattgcttct tgttcccgtg tgatgtttgg cgaaaaagtt
    31561 gcttctgact cgtcttgagg tactggtttt tgtccatcca aaatattggg caatgtttct
    31621 agcaatagct ttcttcctaa aaggctaagc ttttcaaaca tcgtccctac atcatcttgt
    31681 ttagtgattg gtatgctttc ttgcgcatag attccgcctg catccatttt tttgatcatt
    31741 tccatgatcg ttacaccagt ttctttctcc ccattcatga tggcataatg aacaggcgca
    31801 cctccccgat atttaggaag taaagaagca tggacattga ttgcccctaa ttttggtact
    31861 tgcaataact tttcaggcaa gaattggcca aatgccgcag tgacgatcac atcaggcacc
    31921 aattcaatga tttcttccat ttctggcgaa ccggagattt tctctggctg cagcacacgg
    31981 ataccgtgct tcagagccgc ttcttttacc ggtgtcggcg taattactcg tttccgccca
    32041 actggacggt cgggctgtgt taccactgcc tggatctcgt aacctgattc tatcagccct
    32101 tcaagaatcg gcacagaaaa agcaggtgtg cccataaata ctagcttagt catcaagatg
    32161 ttcctccata tattcttcaa gttcttcttc cgggatctgc tgtatcattt tctcaatgaa
    32221 caagataccg tctaagtgat cgatttcatg ctggaaggca cgggctaaat agccaaaagc
    32281 cgtcacttct atctcttctc cgtctcgatc ataataacgc acggtcactt catctgctcg
    32341 cttgaccgtt ccatagacat gcggaatact gagacaacct tctacgtcaa ggctttcacc
    32401 ttttgcttcg atgatttctg ggttaatcag ttcaaatttc tcgccttcat ctacttcgat
    32461 cacagcaatt ctcttgtttt gtcctacttg aggagcagcg atccctattc cgtcattcgc
    32521 aatcattgtc tcatataaat tgtctaataa agcgattgtc tcgtccgtga ttacatcgat
    32581 tggctgagca gttcttttta atttatcatt agggtggatc aatataggat agcgcataat
    32641 ttggcccttt cttaaataaa gtttaatggt tcgttgtcaa ttgccacaaa aagaccttgt
    32701 cgctgttctt tctggcttcc attcaaaatt tcatccaaaa catgaggaag attcggttca
    32761 tgtttatatt tgatgattag ttgataataa tatcggtttt tcactctcaa aatcatgctg
    32821 ggcgttggcc ctaatagcaa gctttgaggg cttaacactt cttttagctg attggcaatc
    32881 tgaaagattt tctttgccgc tacttgttct tcaggatggc tggcggttat tttcacagta
    32941 aagtaataag gaggatagcc tccacgatgc cgtacatgca tttcctgctg ataaaactgc
    33001 tcataatttt gttttttagc taattctatg gcgtaatgtt gaggattgaa tgtttggatc
    33061 acgacttcgc ctgctttttc cgctcgccct gctcgtcctg aaacttgggt aagcaattgg
    33121 aatgtatgct cactagaacg aaaatccggt aaattcaggg aggtatcagc attcaacacc
    33181 ccaactaatg tcacttctgg aaagtccaaa cctttagcaa tcatttgtgt ccctaataat
    33241 atatctgctt cttttgcacc gaatttttgt aaaatctgtt cgtgtgcccc ttttcttcga
    33301 gtggtatcta catccatacg caaaatccta gcttgcggat aaagttctcg gagttcctct
    33361 tctacttttt gagtacctgt tccatagtag cggattttat tgccgccaca attaggacag
    33421 cgattgggaa taggttcttc atgtccgcaa taatggcagc gcattgaacg tgtatccata
    33481 tgcagtgtaa gagagatatc gcaattagga catggaagaa caaatccaca gtccctacac
    33541 atcacaaaag acgaatatcc tcgacgattg agcagtagga cagtttgttc ttttttgtct
    33601 aatcgatttt gtattttttc ctgcaaatta gcagaaaaag tagaggtccg atgattctga
    33661 aactcttcac gcatatctac gatctcaata gctggaagct gtgcagctgc tttggctcgg
    33721 tggtttaact gcaataactg ataaacgcct ttttgagctc gtgctcttga ttctaaagag
    33781 ggcgtcgcgc ttcctagaac tattgggcaa tgatgatatt tactgcgcca aattgctaga
    33841 tctctcgcat gataacgcgg tgtctcatct tgtttgtaac ttgattcatg ttcttcatcg
    33901 ataatgatca gcccgatatt tttcagcggg gcaaaaatag cagatcgtgc gcctactact
    33961 acttgcgctt cttcccgctc aatcttgcgc cattcatcat atttttcacc ttgggaaagt
    34021 ccgctatgta agaccgcaac tgattctccg aagcgtcctt tgaatcgctc gaccatttgc
    34081 ggagtcaatg cgatttcagg cactaacata atagccgttt tattttctga caaaacatca
    34141 gcgattgcct gaagatatac ttctgttttc ccgctgccag tgattccctc cagcaaaaag
    34201 acctgatctt tttgctgctg acctgctgtg atgatttgtt cgacagcatt tttttgttct
    34261 gcattcagtt ccaatgccgt cgtttggtca aatactcggt ctttataagg gtcgcgataa
    34321 cgttctgatt ctataaactc cagccagccc ttttcttttc cttgattcaa gacagcagta
    34381 ctgattcctt tatttttgaa ataagcaatt ggttcttctt ggctcagttc agataaacac
    34441 aaaagaagtt ctttttgttt cttggcattt tgccgtaatt ttgcccattc ttcttcgatt
    34501 tgcttttcag ttaacaaaga acggaccaaa cgaatcgttt ttactttatt tcgtgtatgg
    34561 acttcatatt tgatatctac taattgctct tggcgccagc gaatcaattg agaaaggctg
    34621 ccttcttctt ctgcttcctt ccaggaaatc acttctcgct gatcaaacaa tacctgaact
    34681 tctggtgtgt ctgccaaagg atagatcaat ttatcatatt ctgctttcat cacactcgga
    34741 agcatcgttt gtagacaagt gattttgaat gcgtaagtaa tttttttcat ataatcagct
    34801 aatgaaagta attcttcatt gaccaccgga gcaaggtcta gcaaacgaat aactgccttc
    34861 aaagatggat tagctgattc ttctgatttt tggatagcca taacaaatcc ttggacatga
    34921 cgattgccat taccaaaagg gacttctact cgcatcccga cttgcaaagc tgtttccatt
    34981 tcagagggaa ccaaataagt gaatggctga tcggtctgca tagtaggtac gtccacaatg
    35041 acttcagctg ttaatgtcat ggttcgtttc ctcctttttt tgtcttttct tatcaagcga
    35101 caaaaagttc cttgcctatt ttactagaga tcgatggatt tgtcttatct tctgccaaat
    35161 cctaacaaaa aattaacagc agataagaaa aaaaagaact gtgtcaaaaa gttcagacac
    35221 agccttttct accagacaat aagtggcgaa tgtttgaaaa ggaaacagct gggtttgctt
    35281 ttctttttag atgttcgctc tatttttctt tattacattt tttgctcttc acggatacgt
    35341 gattccaatt cgtgttgttc acgctctttt tgtgcttgac gttcctcttc ttccatcttc
    35401 aaacgttcac gttttaattc aggatgtgga tcattgacta catttcctgc atcgatttct
    35461 tctaaagctt gaccgacgct ttttactgaa tcaaaagaat ctagagtagg ctgtgcactt
    35521 gcatccaatt catgcgcgcg tttacttgct aaaatcacta gagaatattt tgaatttaca
    35581 cgatctaata gtgagtcaat tgaaggtttt aacatcataa gactacatct cctttaacat
    35641 tttaatatat ttaccgatta cgcgatctac tcgaaaatgt tcactggcaa taatgttttt
    35701 gattcgttca actgctagcg gcacttcatc atttacaaca gcatagtcgt aaagagccat
    35761 catttcgatt tcttcttttg caactttcat tcgttcttcg attacttcat ctgcatctgt
    35821 tcctcggcct acgatccgtg attttaattc cgctaaatct ggcggagtca aaaagatgaa
    35881 tacaccatcg ggcacttttt ctttgacttg ttttgctcct tggacttcaa tctccaagaa
    35941 aacatctttt ccttcatcca atgtcttgtt gatatatgac aaaggagttc cataataatt
    36001 cccgacatat tctgcgtatt ccagcatctc tccagcttcg atcattgatt caaactcttc
    36061 tttgcttcgg aagaaataat caacgccttc gacctcccct tcacgcattt tacgggtagt
    36121 cattgagatc gaatactgaa aatcattatc ctcactctca aaaattgctt ttcgtactgt
    36181 gccttttcct acaccggatg gaccagacaa cacgattaat aatccacgct ctgacatgac
    36241 gacgtccttt caactagtct ttttgtactt atcgtttatt ttgcactttt tttctgcaac
    36301 tttcaaggtt atctttaatt atagctagaa attggtaaaa aagctaccct gtaccaagag
    36361 gtcgtaaaaa agctgtcctg catcaagtaa taagaacagc caaacataaa cagcttctca
    36421 tgtttttcgt ttggttgggg ttattatcgc agatgcaagc ttttgaacgc cgtgtataag
    36481 aggtcgtgaa gaagccgatt agtttcgagt atgaagaaaa attttgtgaa aatagtttct
    36541 cacatttttg cataaatttg gcttaata
//
LOCUS       DADQDV010000023        34961 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.023, whole genome shotgun sequence.
ACCESSION   DADQDV010000023 DADQDV010000000
VERSION     DADQDV010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 34961)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34961)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34961
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.023"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            155..1861
                     /locus_tag="J8S10_001225"
     CDS             155..1861
                     /locus_tag="J8S10_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin/fibrinogen-binding protein"
                     /protein_id="HAZ9629815.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            complement(2019..2921)
                     /locus_tag="J8S10_001226"
     CDS             complement(2019..2921)
                     /locus_tag="J8S10_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAZ9629816.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(2918..3622)
                     /locus_tag="J8S10_001227"
     CDS             complement(2918..3622)
                     /locus_tag="J8S10_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HAZ9629817.1"
                     /translation="MKKNMDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKG
                     EETKIEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSE
                     HIINGKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVN
                     PDVFFPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPI
                     QPLNGREIYYFEEFEQ"
     gene            complement(3653..4294)
                     /locus_tag="J8S10_001228"
     CDS             complement(3653..4294)
                     /locus_tag="J8S10_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAZ9629818.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            complement(4332..4646)
                     /locus_tag="J8S10_001229"
     CDS             complement(4332..4646)
                     /locus_tag="J8S10_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629819.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            complement(4634..5263)
                     /locus_tag="J8S10_001230"
     CDS             complement(4634..5263)
                     /locus_tag="J8S10_001230"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HAZ9629820.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            complement(5270..5986)
                     /gene="pyrF"
                     /locus_tag="J8S10_001231"
     CDS             complement(5270..5986)
                     /gene="pyrF"
                     /locus_tag="J8S10_001231"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HAZ9629821.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            complement(5983..6915)
                     /locus_tag="J8S10_001232"
     CDS             complement(5983..6915)
                     /locus_tag="J8S10_001232"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HAZ9629822.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            complement(6912..7688)
                     /locus_tag="J8S10_001233"
     CDS             complement(6912..7688)
                     /locus_tag="J8S10_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HAZ9629823.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            complement(7742..10927)
                     /gene="carB"
                     /locus_tag="J8S10_001234"
     CDS             complement(7742..10927)
                     /gene="carB"
                     /locus_tag="J8S10_001234"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HAZ9629824.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            complement(10932..12008)
                     /gene="carA"
                     /locus_tag="J8S10_001235"
     CDS             complement(10932..12008)
                     /gene="carA"
                     /locus_tag="J8S10_001235"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010744830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HAZ9629825.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            complement(12013..13293)
                     /locus_tag="J8S10_001236"
     CDS             complement(12013..13293)
                     /locus_tag="J8S10_001236"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HAZ9629826.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            complement(13312..14238)
                     /locus_tag="J8S10_001237"
     CDS             complement(13312..14238)
                     /locus_tag="J8S10_001237"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HAZ9629827.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            complement(14251..15534)
                     /locus_tag="J8S10_001238"
     CDS             complement(14251..15534)
                     /locus_tag="J8S10_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HAZ9629828.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            complement(15548..16087)
                     /gene="pyrR"
                     /locus_tag="J8S10_001239"
     CDS             complement(15548..16087)
                     /gene="pyrR"
                     /locus_tag="J8S10_001239"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015694870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HAZ9629829.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            complement(16322..17233)
                     /locus_tag="J8S10_001240"
     CDS             complement(16322..17233)
                     /locus_tag="J8S10_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAZ9629830.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            complement(17230..17694)
                     /locus_tag="J8S10_001241"
     CDS             complement(17230..17694)
                     /locus_tag="J8S10_001241"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HAZ9629831.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            complement(17699..18397)
                     /locus_tag="J8S10_001242"
     CDS             complement(17699..18397)
                     /locus_tag="J8S10_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAZ9629832.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            complement(18384..18770)
                     /locus_tag="J8S10_001243"
     CDS             complement(18384..18770)
                     /locus_tag="J8S10_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629833.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            complement(18917..20587)
                     /locus_tag="J8S10_001244"
     CDS             complement(18917..20587)
                     /locus_tag="J8S10_001244"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HAZ9629834.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            20770..21003
                     /locus_tag="J8S10_001245"
     CDS             20770..21003
                     /locus_tag="J8S10_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HAZ9629835.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            complement(21102..21533)
                     /locus_tag="J8S10_001246"
     CDS             complement(21102..21533)
                     /locus_tag="J8S10_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HAZ9629836.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            21612..22025
                     /locus_tag="J8S10_001247"
     CDS             21612..22025
                     /locus_tag="J8S10_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HAZ9629837.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            complement(22063..23211)
                     /locus_tag="J8S10_001248"
     CDS             complement(22063..23211)
                     /locus_tag="J8S10_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HAZ9629838.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(23333..23929)
                     /locus_tag="J8S10_001249"
     CDS             complement(23333..23929)
                     /locus_tag="J8S10_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAZ9629839.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            complement(24129..26771)
                     /gene="alaS"
                     /locus_tag="J8S10_001250"
     CDS             complement(24129..26771)
                     /gene="alaS"
                     /locus_tag="J8S10_001250"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HAZ9629840.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            27159..27590
                     /locus_tag="J8S10_001251"
     CDS             27159..27590
                     /locus_tag="J8S10_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAZ9629841.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            complement(27635..28984)
                     /locus_tag="J8S10_001252"
     CDS             complement(27635..28984)
                     /locus_tag="J8S10_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAZ9629842.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(29054..30217)
                     /locus_tag="J8S10_001253"
     CDS             complement(29054..30217)
                     /locus_tag="J8S10_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629843.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            30346..30669
                     /locus_tag="J8S10_001254"
     CDS             30346..30669
                     /locus_tag="J8S10_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629844.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            complement(30852..32201)
                     /locus_tag="J8S10_001255"
     CDS             complement(30852..32201)
                     /locus_tag="J8S10_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAZ9629845.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(32270..33223)
                     /locus_tag="J8S10_001256"
     CDS             complement(32270..33223)
                     /locus_tag="J8S10_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HAZ9629846.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            complement(33325..34515)
                     /locus_tag="J8S10_001257"
     CDS             complement(33325..34515)
                     /locus_tag="J8S10_001257"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HAZ9629847.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
BASE COUNT         9951 a         7642 c         6120 g        11248 t
ORIGIN      
        1 cctaaaaatt tggatttcaa cgatagaaac actgtttttt atgtaattag tccaagattt
       61 ttctagactt ttgctttact attcggccaa attggttttt cttctttttt tcgttataat
      121 gaatatactt atgaaaagaa atgaggaatg aaccatgtcc tttgatggtg tatttaccca
      181 cgcgatggtc aacgaattgc gtgaaacgtt actatctggc cggatctcga aaatccatca
      241 gccttatgaa aatgaaatcg tgctggtgat tcgttcacgc ggcaaaaacc atcgattatt
      301 attatctgcg cacccaagtt atgctcgtgt acagattacc caaatcgatt atcagaatcc
      361 tgataatccg cctaacttcg tgatgatgct tcgaaaatat ttggatggcg ctattttaga
      421 agacatcgaa caaatcgaaa atgatcgagt gatccatttc cactttgcta aacgaaacga
      481 gttgggtgat ctacaaaata tcatattgat cgttgaatta atgggacgtc atagtacgat
      541 cgtcttagtt aatcgagaaa ctggaaaaat actggatgcg atcaaacaca ttggaagctc
      601 tcaaaacact tatcgttctt tgcttcctgg tgtagaatat gttgctccgc caaaacaaga
      661 ggtcttgaac ccatttagct ccgagaaaga aaaaatcttt cagcggcttt cccaaactga
      721 actagatcca aaagcaatcc aacgtcagtt tcagggaatc ggtttcgata tcgctcaaga
      781 gctgaccaaa agattactgg aacgtcctaa tgaaaagatg gttgtatggg acgaattttt
      841 ctcagccatc agccatcagc ctattcctac tttttacgaa acggaaaata aagatttttt
      901 cacaccgatt gcttatcagg tattgtccga acaggcatct gctgtaacag cttatccaac
      961 actcagtcaa ttattagata gctattatca cgaaaaagca gagaaagatc gggcaaaaca
     1021 acaaggcgga gaactgattc gaaaaatcga aaatgaacta aaacgaaata aaaataaatt
     1081 gaaaaaacgt gaacaaacac tcaaagaatc cgaaaacgct gagaattacc gtagaaatgg
     1141 cgaactactt actacttttc tgacacaagt accacgcggc gcaaaagaag ttgttttacc
     1201 taattattat gaagaagatc ggccaatcaa aatagcacta gatccggcat tgacaccaaa
     1261 tcaaaatgca cagaaatatt tccatcgata ccaaaagctg aagaacgctg ttaagctgat
     1321 tggcgaacaa atccaagaag ccaaagatga aatccaatat cttgaatctg tcttatctca
     1381 actggaaatt gccggcccaa tggatatcga agcaattaaa gaagaattga cttcagaagg
     1441 atacctgaaa aagaagaact taaaaaaaca aaaacgtaag aaaccatctc agcctgatca
     1501 atacttttct tctgacggaa cgctcattct tgttggtaaa aacaatcttc aaaatgacca
     1561 gctgacaatg aagacagcta aaaaaaccga ctattggctt catgcaaaaa atatacccgg
     1621 ttcgcacgtc atcattaaaa gtgacaagcc ctcagatgaa acaattacag aagctgccga
     1681 gttagctgcc tatttttcaa aataccgata ctctgcccaa gtgccggttg atcttgtaca
     1741 ggtaaagcat atccgaaaac caaatggcgc caagcctggt tatgttattt atgaaaacca
     1801 aaagacgatt atcgtgacac cagaagaaga aaaaattaca gctatgaaac aaaacaggta
     1861 atcaatgagt gtttctagaa tcatatttgc gtactttccc acaacagcaa ttagttataa
     1921 attgtttgct acaaaaagag gagttgtgac aaaattctgt cacaacccct cttttttgat
     1981 caacggtgtt caataaacag cgttctcatc tgcttttctt agctctgctg gtccagtaac
     2041 cgagtaagct ctttgataaa tctttgagcg atttcactga gcggacgttt cgccgaataa
     2101 atgatataaa attcatttag ttcgccttct gccaaaggga ttaaccgcaa gtgctcgcga
     2161 atccctccaa tcacaatacc agatcctgaa gcgtaagcat cagtttcaag aacgatattc
     2221 atcaaagtac ctcgatcact cgtataaatc actgtttctt gatcagggat ctcgataagg
     2281 tcttcataaa aatacgggaa attatttcca tcctgtgtaa aacgaacttg aggataagat
     2341 aacaattctt ctttggtgat ctctgcgtgt tcagctaatg gatgtccttg ccttaaaaaa
     2401 atatgcgttt tgaattttcc aatgctgcgg ccacttagct ctccttgttg taaatatctt
     2461 ctgataccag cttgattatg ctcattcata taaataatgc cgatctcact gtgctgctct
     2521 ttgacttctt cgatcactct cgctgttgtc gtctccatga tccgaaattg tttgatctcg
     2581 tctttgaatt cctcgagtag ctgtgcggtc aaaggaccta agaaatcata atgctgggca
     2641 gcgatcgaaa aattgtctct cttttcactc gttagatagt gagtttctaa tgtatcaagc
     2701 tggaccaata ttttctcggc acgatttaag aagtcttgcc cttcttctgt taaatatgcc
     2761 cctcgattcg ttcgagtaaa cagcgtgatc cctaactcgg tttctaattc tttgatacca
     2821 gctgaaagac ttggctggga gacaaacatt ttctttgccg cttctctgaa actaccattg
     2881 tttgctacag cgaccacgta tttcatctgc tgaatattca ttgctcaaac tcctcgaaat
     2941 aataaatttc tcttccattc aagggctgga ttggtcggtt gttcggtcga gcatactgac
     3001 catcgaaggg gagaagaaac tcttggttca gttttcctac atgatccatt acaaaccatt
     3061 ggattggccc gctggtaggc ggagttgtca atgagccaat ataatggaaa tggctttttt
     3121 gctccggaaa gaacacatcc ggatttaccc aatgctcatg tttttctaag ttccaacttt
     3181 ccccattttc ttgattatac agccaacctt cctgtaccat tagctggtac atgacaccca
     3241 caactagatt ctcttttttg ctgttcatat gaacaaaatg aaattcaata tcttcctgtt
     3301 ttccgttgat gatatgttca gaaggcaagt ggaaatgaat atctgtcaaa taatagcgtt
     3361 ctttcttgaa ctctacataa ctgagttggt caaaaggtac taaatgaatc gtgtttttga
     3421 attccttgtc agtaaaccgt tgcttttgat aatgaaagga aagcgtgtct ccttctattt
     3481 tggtttcttc ccccttggtc aaatgaatag gcgactgcaa tggaaattcc gcacctctcg
     3541 caaaccaatc acataaactc gcccaatttt ccggaccttt gtctccagaa tagccccatt
     3601 cgacatccat attctttttc aactatactt ccccctgcat ctcatatcat ttttattttt
     3661 cttctttctt tacaatcgtt gagacggttt ctaaaaacgc ctcttttcca taaaattcct
     3721 ggttcaatag ttccggaaat atctctttaa agaaatactg aacagaaggc cgatgttcaa
     3781 agcttttaat cgtagtcact gcctcaatga acatctcctt ataaactttt tccgggttat
     3841 ttttgatgat ttcatcaaaa gattcataaa gaaggtcaac cttatctgaa atggctaata
     3901 gttctccttc tacggtttca tcttttcctt cgaacaaccg acggcgataa acttcttgga
     3961 actcagctgg aatctcttgg ttgatgaatt cgtccgtcat cttttcttca actgtttgca
     4021 gcatccctct taactctttg cttgcgtatt tcaccggcgt tttgatatca ccaataaaac
     4081 gctctgtgta gtcatgattc aatgattttt catagagcag tttccaatcg atcggttgtc
     4141 cattcgcttc ttcaatgtct cctagaactt gcgcaataga tgctacacga tacgaatgtg
     4201 ctgcaactgt atgctctgta tatttaaaaa atccaggtgc ccttgtgatc gtctctaaat
     4261 tgttcaatcc taaaataaat tcattcaacc ccataaaagt tacctccctt tgagatttct
     4321 ttttccgaat atcatatcat taaataactg atattcgcaa catttccgct ctttaccatt
     4381 tttgaaacag ctcccttacc aaaaaataga gaaaatctat atataataga aaaaagagaa
     4441 gagattattc tcttctttct gctaaccagt cttagaaaaa tgaattttaa aaaaatcaaa
     4501 aactgatcac gatagaagtt tcttttcata cctgatgaaa agatgcttct cgcaatcagt
     4561 ttttggattt ttgctattcc aattgatgat tctggagaca caaatcggat ttctctatct
     4621 tcatcaagcg cgcttaaatc tgccaatttt caggatcttt tttccattct tttagcagag
     4681 ttaattcttg ctcatcgata taacgatctt ctaaagctgc ttcaatcaat acagaataat
     4741 tggtcaacgt cataagaggg atttcggctt tttcgaaatt tgcttttcct tttggcaact
     4801 catacgtaaa gatagccgca acaccaagga tatccgcacc ttctcttttt gctgcttcag
     4861 ctgcttccaa gacacttccg cctgtagaaa tcaaatcctc gatcacaacc atcttctgac
     4921 cttcaaatat acgtccttcg atttggttac ctttcccatg atctttcgcc ttacttcgaa
     4981 tatagaccat tggcaaatcc agtatttccg ctacccatgc ggcatgaggg attcctgctg
     5041 ttgcagttcc agcaatcact tgtacttcag ggtaagcttc tttgattttg cttgctaatc
     5101 cttttgcgat ctcttttcgg acttttggat agctcatcgt gattcggtta tcacagtaaa
     5161 ttgggctttt gattccactt gcccatgtaa aaggattact tggatttaaa aatactgctt
     5221 caatttctaa taagtctttt gcgatacttt gttcaacatt cattttaggt tagctccatt
     5281 ctgtttgaat cgtttgatat gctttataag gattagttga ctgagtgatt ggtcgaccta
     5341 taacgataaa agttgagccg atcttttttg cctgagaagg tgtgactact cttgtctgat
     5401 ctcctgcgac tgttccttct ggtcttatac ccggagttaa gcaaacaaat tcgtctcctg
     5461 ccatttcttt gatcgcttct acttcccaag cagaagaaac cacaccatct aatcctgctt
     5521 ttttggcaca gctagcataa tggatcacac ttttttctaa agaaacttcg attagttgat
     5581 cggcatgcat ttcttcttca cttgtagaag taagctgagt gatagctaga agtagcggac
     5641 gttttccacc ttctggagtc ccctcttcta atcctcgcat tgccgcctcc atcatacgaa
     5701 taccgccagc ggcatgaaca caggtgagat caacaccaag ctttgccaat ccccgcattg
     5761 ctttttcgac cgtattcgga atatcgtgaa gtttcagatc taaaaataca ttatgaccag
     5821 cctcttttag ataacgtacg atttcaggtc cttcttggta gaacaattcc attccgattt
     5881 tcacaaacaa tttttcttct ttcgggaaaa atcgaagaaa gtcttctacc tcttgcctag
     5941 ttgaaaaatc taatgcaata attggtcgtt ggtctagttg attcatcgtt cacgttcctc
     6001 tctcacttct ttgattaatc tttccagcga ttcgatgcct agttcgctca ttcgcacagg
     6061 gagctcttta attagtttag gacagatata cggatcggtg aaattcgcgg tccctatagc
     6121 tacagcactt gctccagcca taaacatctc aagaacatca tccactgtct gcacgccgcc
     6181 catcccaatg attggaaggc tggatatact tgctacttgg tgaatcaaac gaatagcgac
     6241 aggcttgatt gctggtccgg agagtccacc tgtttgattg gctaaaatcg gttttcttgt
     6301 cttaaggtca atccgcatac caagaagagt attgatcatc gtaaacccat ctgcccctcc
     6361 agcttcgatt gcctgagcga ttggaacgat gtctgttaca tttggggaca atttgacata
     6421 gacaggaaca gaagaaactt tctttactgc ttgtgttaat tgaaaagcaa catcagaatc
     6481 tgttccaaaa gcaattccgc catgtttgac atttgggcaa gaaatgttca gctcgattgc
     6541 tttcacattt ggtgcttcgc caattttgct acaaacttct acatagtctt cttcacaagc
     6601 accagcaaca tttgcgatga tgggtaactc attgtactcc tctaattctg gaagaagttt
     6661 atgcataaca acgtctagac caggattttg caaaccaatt gcattcaaca tgccagatgg
     6721 tgtttccgcc actcttggcg tgggattgcc aaagcgggca tttggagtcg ttgccttgac
     6781 catgatcgat ccaagctgat tcaaatcata gtattttccg tattctttgc caaaaccgaa
     6841 acagccgctt gccggcatga taggattttt taattctagg ccaggaagtt tgaccgctaa
     6901 aggattctca ttcatataat tacctctcct attttaaaaa tcggtccttc gtcacaaact
     6961 ttcacacttt ttgttcctgt ttcatcttcc ggcgtatgac aaacgcaagc atagcaagcc
     7021 cctatcccac atgccatgcg ggattctaat gataactgga cattttgatg cgaagaaaac
     7081 agctgttcca ctgtcttcaa taacccgttt gaaccacatg caaaaacagc tgtaggttcc
     7141 gtcttcgttc ctaacaataa attaccgaca tttccgtgca taccgtatgt tccatcgtca
     7201 gtagcgattc ttgtttctcc tagacgatta aattcttttt cataataaac gacttcatgt
     7261 gtggcaaaac ctaaaaaatg cgttggctta attccttttt cgactaactg ttttgataac
     7321 tcatatagag gagggacacc gattcctcca ccgattataa atacttcgtc tcctgtatga
     7381 agattggaca aatcaaaacc attgcctaaa ggacccatga catctaaatg gtctccggca
     7441 gaaagagtag agaagactct agtcccctca ccttccaccc gataaatgat acggcaagta
     7501 tttgtttcgt ggtcgatatg attcaagcta atcggtcggc gtaatagcaa gtctgcacgc
     7561 ggcacgagaa tatgcaagaa ctgtcctggt tgctgcattt cttttactag atcacctttc
     7621 aatgtcattt caaaaatctt tggtgccagc tgtttttgct gaacgatttc catcatttct
     7681 tgtttcatct gtcccctcct gcaacggttt ttcgtctttt tgtcttaaca tgtgctcgcc
     7741 gttaaatagg gttagttgaa aaagcacggg attccatcac tcgaacgatc gcatctgctg
     7801 tgtctaaaga agtaaacaat ggaataccat gttcaactgc ttctcttcgg atgatgaaac
     7861 cgtctttaga agcatttccc cgatctttat caatcgtatt gacaaccact tgtgttttac
     7921 catctcttat taagtcgact acattttttt ctgctgcttc ctcagaaatt ttcgctactg
     7981 tttcaacgac cagaccattt ttttcgaaat aagcagctgt atgtttcgtt cctatcagac
     8041 tatagccaat ttctgtaaaa cgtttagcta attctagtgc ttcttctttt gtttcgtccg
     8101 caatcgtaaa taatacggct ccatattcag gcaagtgtaa tccagaagct tcgaatgcct
     8161 tgtacaaagc tttgtctaat tgtctgtcag atcccattac ttctccagtc gatttcattt
     8221 caggccctaa gtaagtatca actttctgca atttcgtaaa agaaaagaca ggtgctttaa
     8281 catgaacttc ttttgtttct ggataaagtc cgttttcata accaagtgtc tttagtttct
     8341 ctcccaaaat agctttcgtc gcaatttgtg ccattggaat tcctgtcacc ttacttaaga
     8401 atggaacagt ccgacttgct cgaggattga cttcgatcac ataaacctca ttttcatgga
     8461 tgacaaactg gatattcatc atcccgacac aattcaaacc taatgctaag cggatcgtgt
     8521 aatcttcgat cgttttcttg atcgattcag ataatgtttg aggtggatac acagccattg
     8581 aatcccctga atggacacca gcacgctcaa tatgctccat gatccctggg atgagtactg
     8641 tttcaccgtc acaaatcgca tccacttcgc attcaccacc aagcaagtaa cggtccacta
     8701 gtactggatg ttctggagat gctttcacag catgttccat gtaatcttct aaatctcgct
     8761 ggttttcaac gatttccatc gcacgtccgc ctaatacata gcttggacga acaagaactg
     8821 gataaccaat tctcgaagcg ataaccacgg cttcttcttt acttgtagca gtatccccta
     8881 aaggttgagg aatatccaac tctttcagcg cttgctcgaa taaatcacga ttttccgcac
     8941 gatccaagtc ttcgatcgtt gtccctaaga tttttacacc agcagcagtc aaaggttcgg
     9001 ctaagttgat tgctgtctga ccaccaaatt gaacgattac tcctatcggc tgttctagct
     9061 cgatcacatt catcacatct tcgaaggtca atggctcaaa atataattta tccgaaatag
     9121 aaaagtcagt cgaaactgtt tcaggattgc tgttcatgat gattgcttcg tatcctgcct
     9181 gctggattgc tttgacagaa tgcacagtcg catagtcaaa ttcaacccct tgtccgatac
     9241 ggataggacc agatcccagt actagaattg agggcttttc tgatcgtgaa ctttcatttt
     9301 catattcata ggaactataa aaataaggtg tttttgattc gaattccgct gcacaagtgt
     9361 caaccatctt atatacagga atcaaatcat tttcttttct catctggcga acggcttctt
     9421 cgtttatttc ccacagctcc gccacttttt tgtctgtaaa accgttttgt ttcgctgttt
     9481 tcaatatctt gtcatccaac ggctgctgtt tcaactgctg ttcgatttct acgatatgca
     9541 acagtttatc taaaaagaat aaatcgattt ttgtcaaatc cgctaattct tctatggtgt
     9601 accctcttct aatagcttca gctacataaa acaggcgatc atcttgtgct cgaaccactt
     9661 tttggattag gtcatcgtcc gtgatgtctg ccaactcagg aagttcgata tggtgtgtac
     9721 cgatttctaa agaacgcaca gctttcaata aagactcttc gatattccga ccgatagcca
     9781 tcacttcacc agttgctttc atctgcgtgc ctaaaagccg ttctccgttt tcaaacttat
     9841 caaacggcca gcgaggaatt ttagctacaa cataatctaa tgcaggttca aattctgcaa
     9901 aagtcgttcc tgtaacagga tttttcattt cgtctaatgt taatccaagc gctattttag
     9961 cagctagctt agcgatcgga tagccagtcg ccttacttgc taacgcagat gaacgagaaa
    10021 cacgcggatt gacttcaatc acataataat taaaactatg tggatcaaga gcgagttgga
    10081 cattacagcc tccctcgatc ttaagtgctc gaataatcga aagagaagca tcacgaagca
    10141 tttgatattc atggtcagac aatgtttgac taggggcaaa tacgatagaa tcacctgtat
    10201 ggatacccac cgggtcaaaa ttttccatat tgcagacaac gattgcatta tcagccgaat
    10261 ctctcatcac ttcatattca atttctttaa aacctgcaat acttcgttca atcaaacatt
    10321 gggtagcggg ggaaagactt aatccatttt ctgatacgat acgtaattct tcttcatttt
    10381 cacacatacc tccaccagtt ccgcctaaag taaaggctgg acgaacgatg acaggatagc
    10441 cgattttatt tgcaaaatct acagcttctt ctactgtatt gacgatttca gactcgggga
    10501 ttggctgatt caattctttc atcaactgtt tgaatagatc acgatcttct gcttgatcga
    10561 tcgcagaaag ctttgttcct agaagttcta tgttcaattc ttctaaaata cctgatgctg
    10621 ccagctccat tgccatattg aggcctgtct gtccgcctaa agttggaagg agagcatctg
    10681 gacgctcttt tcgaagaatc cttgatacaa attcaagtgt gatcggttcg atatatactt
    10741 gatctgccac ttctttatcc gtcatgatcg tcgcaggatt agaatttact aaaaccactt
    10801 catatccttc ttcttttaag gcaaggcagg cttgtgttcc tgcgtagtca aattctgcgg
    10861 cttgaccaat gatgatcgga ccagatccaa tcaccataat tttcttgata tctgtacgtt
    10921 tcggcatctg tttactgctc ctttcctgcg tccatcattt ccataaattc atcaaataaa
    10981 tgtagtgcat catgcggacc aggggcagca tctggatgaa actgcacact gaaagcggga
    11041 taatctctgt gtttgactcc ttctactgtt ccgtcattta cttctacatg agttacgatg
    11101 agtttttctg gatcaatcgt ggcttcatcg actgcatagc catgattttg agaagtaaaa
    11161 tcaattcttc cggtcgctac ttctcgtacc gggtgattta atcctcgatg tccgaatttc
    11221 attttatagg tatctgcacc gttggctaaa gcaaataact ggtgaccgag acaaatacca
    11281 aaaatcggta cttttccttg gatttttttg atcatttcga ttgcttctgg cacatctttt
    11341 ggatcaccag gtccattcgt cagcatgact ccgtctggtg atagcgctaa aatcgtctcg
    11401 gcatctgtgt tatagggaag tactgtgagg ttacagtttc ttttactcaa ttctcgtaaa
    11461 atactatgtt tcaagccgaa gtcaatgaca atgactttcc gacctgttcc tggacttgga
    11521 taaggtttgt tagttgagac ttgctgcact tgattggttg ctagaacggt tgctttcagc
    11581 tgatcaaatg catgttcgaa ggaatctcca gcatcaacta tactagcttt catcgttccg
    11641 acttcacgga ttttgcgagt aagggcgcgc gtatcgatac ctgatattcc aggaattcct
    11701 ttttgtttca aaaatgaatc tagcgtcatt tggtttcgcc agtttgaagc tacacgtgca
    11761 tgttctttta ctactactcc tttgcatgtt ggagaaatcg attcataatc atctctattt
    11821 accccataat tacccaccat aggataggta aatgtaatga tttgaccgtt aaaactttga
    11881 tcagtgatag tttcttgata accagtcata cttgttgtaa aaacgatttc tccgaagaca
    11941 ctagcatctg caccaaaagc ctttccttcg aaaactgttc catcttctaa tataagcaaa
    12001 cgttccatac ttttattctc ccttctgcca cacaagtttt ccgttgacaa aagtcatttg
    12061 tgtttcgcct tttactttcc agccgataaa aggtgtattc tccccttttg ataaaaagtc
    12121 ttctttatcg atcgtgcaag tttgtgtaat atcaaaaact gctacatcag cgggggcacc
    12181 aaccgttagc gttcctgcat tcaaaccaaa aatctcagcc ggtttaactg ccaaccaatt
    12241 gatcacttgt tccaacgtga atcgaccagt ttctacaaaa tgagtataga tcagttgaaa
    12301 cgctgtttcg cttcctacga taccaaatgg tgatttcatg aaactttggc ttttttcttc
    12361 taatccatgg ggggcatggt ctgtagcgat gcaatcgatc gtaccgtcaa gcaagccttc
    12421 gatcaaagct tctctgtcct cccgtcctct tagcggcggg ttcattttcc aaaagccgaa
    12481 atcttcggga atatcttcgt cgatcaaaat aagatgatgg ggtgaaactt ctgctgttac
    12541 gtggattcct gctttttttg cgtctctgat tacacggaca ctttctttag tagaaacatg
    12601 gcaaacatgg taatgaacac cagttgcttc agctagcaac agatctctag caatttgaga
    12661 agactcggtt acgcttaaga tcccgggaag accaagttct tctgccttct tgccagcgtg
    12721 cataacgccg ccaaataata aagattcatc ttctgtatgg gctactaggg ctttattgtt
    12781 ttttgcagct tctttcatag ccagatacat cgtcccagct gtttggacac ctacaccgtc
    12841 atttgtgaaa gcaaaagcac cttcttcaat cagtgcttct tgatcaacta atttctcact
    12901 tcgcagattt tctgtgattg gcgcatactg caataccttc acaactgcat cttttctaat
    12961 gatgtcatat acttgtctca gcttttctgc cgtatcaggt acaggattta aattcggcat
    13021 cgcgcataca gtagtgaaac cgccacgagc agctgagcga gtcccagctt cgatcgtctc
    13081 cttgtatgta aatcctggct ctctcaaatg aacatggacg tccactaaac caggtgtgat
    13141 caattgtccc tttgcatcaa acacttcatc aaattcggct tctgagaatc ctgtaccgat
    13201 tgctttgatt cgcccatctt ctatccaaat ttctgctggt gtcgtcatat tttttcgtgt
    13261 attgatctga ccgtttttaa tgagtgtttt cattttttca tcctcctata attacgcttt
    13321 tccatttagc actgcttcta agattgccat tctgacgaat actccattgc tcatttgctg
    13381 aacgatccgc gactgtaatc cttccactaa tgaatcagct aattctacat cacggttaac
    13441 tggtgctggg tgcataatga ttgcatgttt ttgcaacttc ttcgcacgct caactgttaa
    13501 cccatgttcc tgatggtagc cttcttttga gaaactttct tttccatcat ggcgttcgtg
    13561 ttgcacccga agcatcatca tgacatcaac ttgatctagt agttcatcca atggcatata
    13621 atgtccgtac acttcgaatt catcgtcgta ccattctcta ggacctgaga agaatacttg
    13681 tgcgcctaga cgttttaaca tctgcatatt ggatttagct acgcgagagt gagtgatatc
    13741 acctacgatg gcaactttca gaccttcaaa atgaccaaat tcttcataaa tggtcatcaa
    13801 atcaagcaag cattgggttg gatgctgtcc gcttccgtct cctccattga taatcgaaca
    13861 ctggattgtt ttactttgta tcagttcgtc ataatagttc tcatcaccat gacggataac
    13921 cgctacgtct acgcctaatg ctgacatcgt cagtactgta tcgtatagtg tttccccttt
    13981 ttggacagag cttgtgcttg cttcaaattc aatcacttct agccctagtt ttttctccgc
    14041 tacatcgaag cttttatgtg tgcgagtact attttcgaaa aagaggtttg tagcaaagta
    14101 ctggcgcttt tgcggagtcc aattagcacc ttgcttgaat tcctgccctc tgcggatcaa
    14161 gcccataact tcttgatcag taagtgcctc aacggtcaat aaatgcttta agctgatacg
    14221 ttctgatttg atgatcataa tgtttcctcc ttagttttct tcgcttcgtg aagtttctgg
    14281 taagataaga tttaaaatga tgccaagtac agttgctaat gccattgccg acaatgtaaa
    14341 tgtgcctact tcaaagacga gtccgccaat tcctactact aagataactg aagcaatcaa
    14401 cagatttttc tttttatcaa aatcgatttt gttctcgatt aaaatcttca ttccacttgc
    14461 ggcaattact ccaaataaga taaaactgat tcctgagatg actggtccag ggatacttaa
    14521 aatcaaagcg cttaattttc ctacgaatcc taaaatgact gcaaatactg cagctccacc
    14581 gatcacaaac acgctatgga cacgtgtgat agccagaaca ccaatgtttt caccgtaact
    14641 tgttacagga ggacctccga caaaggctgc cacgatttgt gctaatccat cacctgtcaa
    14701 cgtcttatga agacccggtt cttcaaagaa attacgttta gttagtttat tcaataccat
    14761 aagatggccg atatgctctg tcatcgtcac aaaagcgatg ggtgccattg ttgtgattgc
    14821 tccaagatat agctttggtt catattgtac aaagggaatc tcaaagttag gaacagcaaa
    14881 ccaggcagcg tctacgattg gcttagtatc cacgattcca aacagcaagg ctacgatgta
    14941 tccgctaata atacctagta aaatcggaat caatccgaga aaacctctta gccacatgtt
    15001 gaagaaaatt gttaatccta atgtgatcag cgctacagca atatacttga aatcatacgt
    15061 gccctgatta tacatagcat ttgttgctgc atttgccgca agtcccaacc cgataaccat
    15121 gatgactgga ccgacgacga ttggaggcaa gattttatcc agccatgctg aaccgatctt
    15181 tttgatgatc agcgcaacaa tcaaatagac taatccagtt gtgactgctc cttgtgcaat
    15241 cgctggataa ccatctgttt tcatcaaaag ctgcatcgct gcaatgaaag cgaagctgct
    15301 tcctaagtac gcaggtatct ttcctttagt agtaaataag tacaccaatg tacctagtcc
    15361 tgaactgact agcgcaatac ctggatcgat acctactaag atggggacta acacggttgc
    15421 tccgaacatc gtgaacaagt gttgtaaact taatcctacc caatgtcctg gggttgggcg
    15481 atcgtggata tctaacacca cgtcatcatt atgaaatcct tttttctccg acatgtttct
    15541 ctctcctcta atcttcctct ttcaaaatca tgatgcgatc ttgtccatca agctcttgca
    15601 tctctactaa aatctcttcc gcccgagatg ttggaatgtt cttcccaaca taatctgcac
    15661 ggattggcaa ttctcgatgc ccacgatcga ccaggactgc taatgaaatt tttcttggtc
    15721 tgccaaaatc cattactgcg tccattgctg ctcgaatcgt tcgtcctgta tacaaaacat
    15781 catcaatcaa aataacttct tttccttcta aggaaactgg gatgtcagaa gaatgaagtt
    15841 ccggttcttc tggattttct tttttgtcat ctcggtataa agtgatatcc agttctccta
    15901 caggaatatc gatatcttct agctgcttca ggcgttcggc aattcttgat gcaatgtaga
    15961 ttcctcgtgt tttgatacct accaatacga tatcttggat actatggttt ctctcgataa
    16021 tctcataagt aattcgagtc aatgctcgct tcatggttac ctgatctact acttcttttg
    16081 cttgcatttt cattccccct acttttttgc ataaaaaaac tcctgcccta agaggacagg
    16141 aggaatgttt agactgagcg tatactgata cactgatagc tatactatgt caatgagcaa
    16201 tctacttatg gcgcaccata cgtatccttg ctcccaccct tcttagcctc acgggactaa
    16261 acttaaagga attctattaa gttttatgct ttcgttgtta attactatac cgttatctaa
    16321 attaaaatgc aatgtttttt cttaattttt ctaaagtttt ttcaaaaact tctggaagag
    16381 gtgcttcaaa gatcatcttt tcgtttgtag tcgggtgcgt aaaacctaac atttgcgcat
    16441 ggagaaactg accattgcct ttcaaagttt tcttcggtcc gtatactgga tctccagcta
    16501 acggataacc gatatacttc atatgcacac ggatctggtg tgttcttccg gtttctagtt
    16561 ttaattcaac cagagtaaat ccttcgaaac gttccaatac agtaaaatgt gtgacagccg
    16621 acttcccatc ttctcttatc gcctgcattt tccggttttc cttcgaacgg ccgattggcg
    16681 cattgatggt tcctttttcg tgaggaatct ctccatggac taaagcaaca tatttgcgca
    16741 aagaggtctt atcttttaat tgctgagcta atgattcgtg tgcctggtca tttttggcaa
    16801 ccattagcag tccggaagta tctttgtcga ttcggtgaac aatacctgga cgaataacgc
    16861 cgttgatcgt agaaagatcc ttgatatggt acatcagcgc attgaccatt gtgccatgcg
    16921 tatgacctgc tgaaggatga acgaccattc cttgaggttt gtttatcacc gctacatctt
    16981 catcttcgta aacgatcgtc aacgggatat tttctgggac cacatctaat gtttctggtt
    17041 cggggatcaa gacagtaatc tcgtctcctt gttttacttt gtaatttgct ttgactggct
    17101 gtccattgac agaaaccgct ccatttttca gccacagctg aatttgcgaa cgactgtaat
    17161 cggtgaataa attagtcaat actttatcga tcctaccaga ttcatggtga atcgtcgttt
    17221 taagttctgt catttttttc tttgatcctt ttcatctaaa ataatataaa ttaacataca
    17281 aatcactcca catacaagtg tcacatctgc tacgttaaaa atcggaaagc tcataaaatc
    17341 tgtctggaac atatctacta catagccaag acgaatacgg tcgataaaat tgccaatcgc
    17401 accagctaga atcaaactca atccaatcat gaaccagcga ttaccttttt cacgattttt
    17461 aatcatcaat gtgagaatca caacgactgc aatgagtgtc actatagtaa agaaccacat
    17521 cttcccttct agcatactcc atgcggctcc agtgtttcga atatgattca gtgacaaaat
    17581 acctggtata agatttttcg tctctccaag cgctagatta tcagtgatcc accatttgac
    17641 caactgatcc actcctacta gcaaagcgct gaatatccaa taaataatta acaaaaaatc
    17701 aatccttttc tatttgttta taaatatcac gaggtcgtac gatcccgagc agattaccat
    17761 cgggattccc atctttagtg ataagtacgg cttccaaagt cccttgctca cgaaacatcg
    17821 cttcaacctc gtaaatatgt gttttagctg gaacaaaatg ataatttgtg tactttccgt
    17881 tttggatgat caaatccaac gctcgtttat ttgttaaatc aaccggacct ttttggcttt
    17941 cttttgctag ccaaaacccg atattacgta aagtaatcaa tgctacaaat tttcctttat
    18001 tgtataacgg aaattgtgaa tacctttttt ctgctactat ctttaacagt tcaagtaacg
    18061 gaagatcttg ttcaaaacct gttacacgtt ttgcaaatcg aggcagcacg gtttcaggct
    18121 gaatcagttc ttgttcgatc agctggattc gcttgactgt ccaatcattt ggctctgcaa
    18181 tgacaaaatc gactgcgatc cgatcatgga cgatcgcatt ccttaactga gcaagctgta
    18241 aaagatcatc ttcgtatttt ctgatcatta attgttttct ttgagctagg cgtctgacaa
    18301 gttcggtaaa tcccatattt cgtgcatttc ccatctcgtc tctcatccat ttttcgattc
    18361 gattgaaact gattaaaaaa agatcagagt ttgccataat tttcctcctt gatcaaatat
    18421 gcccggtttt ttatatagaa aaagaacgca atcaacacaa taactgcaaa aaaactgaaa
    18481 aataaatttt gtaggaaaac ggcccccaac ccagttgcta gaaataaaaa cggatagatt
    18541 tgaagaatca agtaattcat tgtgatcaca taagcaggct ttgcttcttt cactgtataa
    18601 acggggcttt ttagccaata aaaggtgacc tgcatcgtaa agggcacttc cagatcaagc
    18661 gttatctttt gttcatgact gagaacactg cgtttttcat tgttgattct tagctgaatc
    18721 gagctaccca taccgtaaaa accggttttt cttataaatg tcgttttcat cataccctcc
    18781 tattatgctt tagtatagct caaaatacaa taaagaaaaa gaatgatcct agtgtaaaca
    18841 aaattaattc cctatcgtct aaaaaaagaa gctgtagtca aaatacagct ccttcgatgg
    18901 tagattataa tcaagcttaa aacaatccca acacttctcc gtcatttgtc acgtccatat
    18961 tcaatgcagc aggtttttta ggcaaaccag gcatcgtcat aacatctcca gtcaaggcta
    19021 ctaaaaatcc tgcccctaat tttgggatga tttcgcggat cgtgatggtg aaatcttccg
    19081 gtgcacctag cagtgaagga tcatcagaaa atgaatactg tgtttttgcc atacaaatcg
    19141 gcagtttgtc ccatccattc ttcgtaaact cttctatttg tttttgcgct tttttgctga
    19201 aaacaacacc atttcctccg taaattttct tgacgattgt ttctgtcttt tcttgtatcg
    19261 tttcttctag gcggtataat ggcttgtaat tagcttcttt tctatcaatc aatcgtacta
    19321 cagcttttgc taaatcaacg ccgccttctg ctccatctgc ccatacactc gctctcttgg
    19381 caagaatccc ctgattttca cacaagtgct ccaacagtgt gagttcattg tctgtatctg
    19441 ttacgaattc attgattgcg acgatcacag gtagctgata ttgttccata ttacgtatat
    19501 ggcgctttaa atttgcaaaa cctactttca aagcatcaag attctcattt ttaagttcat
    19561 cttttttcat tccgccatgc attttcaatg cacggacagt ggcgacaatc accacagcat
    19621 ccggcgcttt tttcaagtta ggtactttga tatctaaaaa tttctctccg ccaagatctg
    19681 caccaaatcc tgcctctgtg acaacgtaat ctgctaatct caatgctgtc ttggtagcta
    19741 aaatactatt gcagccatga gcgatattgg caaacggtcc cccgtggaca aaagctggtg
    19801 ttccgtaaat tgtttgtaca agattcggct tgattgcatc tttcagcagt aatgccagag
    19861 cgccttctgc tttcaagtct ccagcagtca caggctgacg gtcaaatgta tagccgacaa
    19921 cgatccttgc aagacgagcc tttaaatctt caaggtctgc cgcaagacac aagatagcca
    19981 tgatttcgct ggcaactgtg atatcaaacc catcttctct tggaacacct tggattggcc
    20041 cacccaagcc aacaattact ttacgcagtt cacgatcatt gagatcgact acccgtttcc
    20101 aaatcactcg gcgggcatcg atgttcaatt catttccttg atgaatatga ttatctaaaa
    20161 gagcagataa tgcattatta gctgttgtga tagcatgcat gtcaccagta aaatgcaagt
    20221 tgatatcttc cataggcaat acctgtgcat atcctccgcc tgcagcacca cctttgattc
    20281 ccatcacagg accaagtgag ggttctcgca atgcaataac agatttttta ttgattttat
    20341 tgagcgcgtc tcctaaccct acagtgatcg ttgactttcc ttcgccagct ggtgttggat
    20401 tgatggaagt aactaagatc aaatgcccct cagcgttatc ctttgatcga ttgattccag
    20461 aaaaattgat tttcgcctta tatttcccat acagttccaa atcgtcttcc ttaagatcta
    20521 atttactagc cacttcaaca atcggttcta gctctgtttc ttgtgaaatt tgcagatcat
    20581 tcttcatttg attacccctt ttcacgaact ttattcaaca aaatatcttc tttgttaaga
    20641 tatgccaatt ataccttttt ttattcagaa aaaaaacata aaattacagg tttttaattt
    20701 atttgacgta cttataaata ctctttataa tgaaggctat gatcagactt tagaaaggtc
    20761 gtgagtgctt tgaccacagg aattgtaaaa tggtttgaca acaaaaaagg atacggcttt
    20821 atcagttatg atgacacaga agaaattttt gtacatttta ctgcgattga agaagaggga
    20881 ttcaaaactt tggaagaaaa tcaagtggtc gaatttgaga tcatcgaagg gaatcgagga
    20941 acacaagctg cccatgtcaa gaaaggcaac gttcagacta ccgatactag tatgcatgaa
    21001 tagataaaca aatagagtga gacgctaaac gggatgaacc gtacgtctca ctcttttctt
    21061 ttcctgtaaa aattcgtttt tttaggttct gatttttaaa attagctttt tctttttttc
    21121 gtataaggat aaggaattga ttctgatttg ggtccgtttt tttcaaaatg atcaaaaagg
    21181 actacttgat ctttttttcg catcatgaaa acagatgggg ctttctcatc ttgcaacatc
    21241 atttgcaccc cagtattagt tggcgtcaaa gatcgaatct gtccgacaga tatttctcgg
    21301 tctttccaaa aagcagcata acgtataatc acagagtttg attttaaaat aaaagaacgc
    21361 cgcaaaccta gaaatagaaa aacaagaaaa atacctaaaa caaaattgct tttccaataa
    21421 ggacctgtgt tttctaaaga aagaatcaga ctaaaaaaca gaatgatcaa ggtcaatgac
    21481 caatagatga tcgtatgtgc cagttcaggc tgccatcgaa tatttttttt cattctctaa
    21541 cctctcaccg attcagtaat gatataatct taccataaca ttagtttgaa caaaaaggag
    21601 aatctctttt tatgttaaaa gtatacattg atgcctctac aaaaggcaac cctggtccta
    21661 gtggaggtgg aatcttgatt gtctatcaag gtaaacaaga acagctatct atcccgcttt
    21721 ctatagggac aaaccatcaa gcagagttcg aagtcttttt aaaaacttta gaatttctaa
    21781 agaaaaacga cttacagaat gaaacgattt tctgtttttc agacagcaaa acactagttt
    21841 ctacggtcga caaaaacgca acgaagaacg agctcttcct tccctacctt caaagaatcc
    21901 aagaacttct atccgaattt tctttattga tcctgcaatg gttgcccgaa aacaaaaata
    21961 aaggagcaga taatcttgca cgtcaggctc tccataaaca attaaaagaa aaaaagactc
    22021 tttaaattaa aaactttaag gagtcttttt atagtttctc atttaatata aaagataatt
    22081 gtgatcaaac gtaatttcca attggtaatc tccgattttt tcttctattt gactacgtaa
    22141 gattctttct agttctgtat caacaaactg gaatttctca gggaccacta catcaaattg
    22201 cagcgttttt ccttgatgaa ttactctaaa atcatgaata ttaagccctg tacctgtttc
    22261 aagaagaatt tgctttaact gccgcaagat attatagtat ttttcgttat caacaggcat
    22321 tggatccaag tgacagacaa gttccacatc caaagacttt ttaaagtctt tttctatcag
    22381 atcaataatc ttatgagcca cattcaaatt cattgattca tctacttcga tgtggactga
    22441 tgcaaagcgt ttattgggtc catagttatg caccaataaa tcatgatagc caagtatatc
    22501 atcgcaagca tttaaatgct cttccatttc ttcaatctct gctggcgttg ggcgacttcc
    22561 taatagttcg tatacaaaat ttcgaagcat cgtcaatcca ctataaagga tatataatgc
    22621 taaagcaaaa cctatatatc catcaatacg ccatccagtt acccattcga ttgctgctga
    22681 aagcaataca gccagtgtag taaagacatc attataacta tctgttgctg tagctctcaa
    22741 tgtttcagaa tcaatggatt gcgcaataac ctgatacatt ttgccttgtg caaatttcaa
    22801 aaagatggaa atgattagga caaaaaagac gatgggtgtt aaagagacat tttctggatg
    22861 gatgattttt tcagcagaag actctaaaaa ttgaaatcct acataagtaa tgatgatcga
    22921 aacaaataac ccactgatat attcgaagcg ttcgtgtcca taaggatgtt cctgatctgc
    22981 tggctttgca gcaattttaa atccgatcaa agtcaatatg gatgaagcag tatctgatag
    23041 actgttcact gcatcagcca taatggagac acttcctgaa aaaagcccga tcattagctt
    23101 agagacaaac aagatcagat tcgtaaccaa tcctaagata cccgctagta ctcctttttt
    23161 tgtccgctgt tgcggtattt gtttcttttt ttcttcttgt ttcttagcca agttttttac
    23221 cccttctagt ttgcttgttg ctcaggtaaa aagatggaga ggacgattgt tttcctctcc
    23281 tctcttcctt tttctatcta tcgtgcgtcc tattactatt aaaagatggt cattattctg
    23341 gtttcaacgg tgttgctgca aataacgctt ttgctagtaa tggtgttatg attcccgcac
    23401 ctattgcttc tggtatccca ttgattgctg caacccctgc taaggtttta aataaaagag
    23461 cagagtctac accataggca tctgccgttg cacctgtata aaataatccc atgaatccta
    23521 acactaagac tgtattgacc aatgaaccca gtacccctgc aaaggctgag ctgatcgtta
    23581 ttgatttatt tttttgataa atccagtgga aaaccaagcc tgctactaag ccaacaagta
    23641 ctctgggaac taccgagata atcggattcg tgaacactaa tgtatcaaat ggcgttgttg
    23701 gcatggcata ggcacgaaca attgtagcga ttccccaaaa caagccaatc accatgccat
    23761 cttttgggcc taatactact gcagcaataa ttactgtgat atggataatt gttaaactaa
    23821 tgaatcctaa tggaataaac cccagccaag gaaccatcgc ttgtacgatg atgattgcta
    23881 acaagatcgc acgtaagact agtcgaaagg tcttatttct actattcatt ttttcacccc
    23941 tttttattta tactaatcgt aaaaatttct gtcactttcg tcaactaaag accatccgaa
    24001 tccgaccatt tgattagatg cgccatccaa ttgaaaaaag tatgagggca agacttgttt
    24061 gtcttcgccc ccataatcat gtttcgttca atgtttgaac ttttgttttt ctgtcaaacg
    24121 taaacgccct attgttgcgc aacccattct ttcgcagctt taagtgcatc tggaatacca
    24181 gcaggatttt tcccgccagc ttgtgccatg tctggacgtc caccaccgcc accgcctact
    24241 ttcggtgcga ttgctttaat caagtcgcca gcttttagtc cagcttcatt tgattctttc
    24301 gtcattgccg ctagcagact gacttttcct tcttgttcgt ttgctaaaac aagaatatct
    24361 gaaatatttt tttgtttcca ttggtcagct aattgacgca gctgattcat atctttcact
    24421 tttacttgtg ctgcaatgat tgtttttcca ttgatcgttt ctggatcttt gaatacatca
    24481 ccagcttgtt gattcgctaa cttgctagct aattgttcat tttccttttg tagctctctt
    24541 acttgctgtt gcaattgttc cgcttttgaa acaacttctt tcaattgagg tgatttaaca
    24601 attgttgcta cttgttttag ttgtttttct tcttcttcaa gtagttcgta cgcttcttta
    24661 cttgttacag cctcgattcg tcgcacgcct gcaccaattc ctgattcaga aacgattttg
    24721 aagattccga tgttttctgt atttgctaca tgtgtgcctc cgcacagttc gattgaccag
    24781 ccgccaatat ttactactcg aacgtcatgt ccgtattttt caccaaacaa agccattgca
    24841 cccatgtttt tggctgtatc gatatctgtt tcaattgttt caactgggat agcttcccag
    24901 attttttcgt tgacgattct ttccatttca gctaattcat ctgaagtgat ttgaccaaag
    24961 tgggtaaagt cgaatcgtaa atgtccagga gcgactaaag aaccagcttg atttgcatgc
    25021 tcgccaagta cttctttcaa tgccttgtgc agtagatggg ttgctgtatg gtttttgatg
    25081 atccgattgc gcatcgattg atcgatcaat agatgatagg tttgtccttc actcattggt
    25141 gcttttactt ctacggtgtg cataaattga ccattaggcg ctttttgaac atctgtaaca
    25201 actgctacga tttcgcctac ttcattcatg atccatcctt gatccgctac ttgcccaccc
    25261 atttctgcat agaaaggtgt ttgatcaaag atcatttgag cttcaccttc tgcgacttca
    25321 ttcaaaagag actcaccttt aacgatgacc aataattgac tatctgattc ttgttctgtg
    25381 tatccaatga atttactttc tactttgata tctgtcaata aagcagattg tacccccatt
    25441 gatttttcag tactgcgggc agagcgagca cgttcgcgtt gtgcatccat ttctttttca
    25501 aaaccagcat gatcaacttt cagtccttca tcttctgcca cctcttccgt taattctacc
    25561 gggaagccat atgtgtcgta tagtttgaag atgtcttttc ctgctagagt cgtcccgttt
    25621 tcgtttttta cttcttggat cacttgattt aagatttcca aaccttcatt gattgtttca
    25681 ttgaaacgtt cttcttctgt acggataact ttttcaataa attctttttg ttgaagtact
    25741 tcaggataat aacttaccat gatttcccca acaacaggga ctaaacgata taagaatgct
    25801 tgttcaatac ctaatttttt cccatgcatg acagcacgac gaagcaaacg gcgtaagaca
    25861 taccctctcc cttcattcga tggcaatgca ccgtcgccaa tagcaaatga aagggcgcga
    25921 atatgatctg cgattacttt gtaagaaata tctgttactg ggttttcacc atattttact
    25981 tgtttgctta gcttttctac ggcgtggata ataggcataa acaagtctgt ctcaaagttc
    26041 gttgacgcat cttgaacgat tgagaccatg cgttccaatc ccatccccgt atcaatgttt
    26101 ttatgaggaa gtggttcaaa tgtgttatca ggcttatggt tgaattctga aaatactaag
    26161 ttccagattt ctaaataacg ttcattttct cctcctggat agttttcagg atcgtcttct
    26221 gctaaatcgt tataagcttc tccacggtca tagaaaattt ccgtatccgg accacatggg
    26281 cctgcaccga tatcccagaa gttgtcttct acatcaataa tgtgatctag tggcaggcca
    26341 acttcttcat gccagatgcg ttttgcttct gtatcttttg gataaactgt tacataaagt
    26401 ttttctggat cgaatgccat ccattttgga tcagtcaaaa attcccatgc ccagtggatg
    26461 gcttcatttt tgaaatagtc accaatcgaa aaattaccca gcatctcaaa catcgtatgg
    26521 tgccgtgctg ttttaccgac attttcgata tcatttgttc gaatagattt ttgggcattt
    26581 gtgattcttg gattttctgg cacaactgaa ccatcaaaat attttttcaa tgttgcaaca
    26641 ccagagttga tccacaataa ggttggatcg ttcacgggga tcaaagacgc actaggttca
    26701 atcgtatgtc ctttagattg gaagaaatca agaaacattt gtcgaacttg tgcactactt
    26761 aattgtttca tgtcattacc tgctttctat aaattaaata caaaaaaaca ccatcacagc
    26821 caaggacgaa aactcgcggt accaccttga ttgcaatgat gtgtaatcat tacctcttaa
    26881 actcgataac gctgagctgc gtcggtattt ctaccaaaat agaaaaaggg agcaatttga
    26941 ttagtgacta ttcttttttc agccaagaaa gaattttctg tgagtcttaa aaaacaaatc
    27001 atatcctttt cgtacttaat tagtatacgc attctattga tcactgtcaa tatctcaatt
    27061 tttattttca tttccttttg gtcatactcc acgatttttg gtacgataag aataaaggaa
    27121 tcaatacatc tctgctattc atgacaagga ggaatatgat gaaaaaaata gttggagcgg
    27181 atgaatggat acgcgcagct agctgctttt tgagatatca agtttttgta ttagaacaag
    27241 ggattcctgc agaactagaa ttcgacggaa aagatatccc gcaacaaacc tattatctat
    27301 ttcttgatca aaaaagacca gtagctactt tgcgttatga aaagaaaaca cctacttgct
    27361 tcaagccgga acgattttgc gtagcaaaag aataccgagg aaaagggtta ggcggtcagt
    27421 tgcttgaagc tgctgaaaaa cgggcggttt cagaaggttg tcagactagt tatgtagtag
    27481 ctgaaatgac ggctgtagat ttttatgaaa aacaagggta tcatacttgc acagaacctt
    27541 ttattgaaga tgaagtactt tgtatcggaa tgaaaaaaag tctagcttaa aaacaagaga
    27601 ttgtgacacg ccttttgtca caacctcttg ttttttattt atgtgaattt ttcttatttt
    27661 tacgagcagt acggctttgc tgtctgcgtt cgattttgcg ttctttttta tttttttctg
    27721 caattgccca atcgattttt ttcttataac caggcttgat ctttttcttt ttcttcttca
    27781 caagaccaat cagcgtggga tctaatacat cttttgattt ttctcgtttg gcacgtctat
    27841 tacgatcgta tgttttgacg atttccccgt ttttgatttc ttttggttca aatgagacgc
    27901 ccaatttttc tatcgcatca atggcttgct catcatttgg cgaatataac gtaatggccg
    27961 ttccttttaa gccattacgt ccagtacgtc cgacacgatg gataaagaag tctagatctt
    28021 ctggaatttc tgcattaata acatgagaga caccttcgat atcgatccct ctagcagcta
    28081 aatcagtcgc tacaacatat tgatactcca gattctgtac ttgtcgcatc actcgttttc
    28141 tctctcttgg ggtgatgtct ccatgaatct ttgctacttt caagccttgg tttttcaagt
    28201 aatcggcaat ttcatccaca tgctgttttg tattggcaaa tacgattgct aaataaggat
    28261 gaccaattgt cagcagttga taaatcattt gattctcatc tttacctttt gttgaaatca
    28321 gccaattttc aatgtcttca gaaataactg cttttggttt gatttcttca atgattggat
    28381 tttccatgta ttttcgtaag aatggacgaa gtttttctgg aatagtggca gaaaaaacta
    28441 aaaactgcag cttttctggt aatcgacttg caatttggtc tacttcattt aaaaaaccca
    28501 tatccaatgt catatccgct tcatcgacaa caaatgcaaa tgcggtgtga atcttcagcg
    28561 cttgttcatt catcatgtct aatattctac caggcgtgcc tactacaacc tgtggctgtt
    28621 ggtgatgcag acgatttaat tgacgctgtt tgtctgtacc gccgacaaaa ttcgagacac
    28681 ggatctccgg tgtagaaaat ttagcgattt gtgtagctgc ttcatagatc tgtgcagcta
    28741 gttccctact tggagctgta ataacaactt gtacttcctc tttttctgca ttgatttttt
    28801 caaacaaagg caacaaaaac gtatgtgttt ttcctgtacc agtttgagat tgcccaatga
    28861 tattttttcc ttttgcaatt aaaggaatca aacgttcctg gacctctgtg ggctgtttga
    28921 agccctttgc ggttaacgct tcattgataa acggtttgaa gcggaatata tcaaaattat
    28981 tcattcgtgc acctcttctc tttaaattat cacgactttg gcattataac acagacaaag
    29041 cgtttttgct cagctaattt cgagaatcat catcctttgt ttggccaatc gtgctaacag
    29101 tatatgtgtg actagctttt tcataaaaca gaatccgttt ttttctcaaa aatgatagca
    29161 agatatttaa aataaaaata ccttgtagta acaagacacc gagagaaatg aatactgcac
    29221 tcatctgcaa caccgtattc gttgtcgaat tcatgatttg ctgaagcaac tgccccaacc
    29281 agcttaaacc ataaaaaaga aagtacagat acccgtagcg gatcatcaat gcttttaaag
    29341 aaattcgttc gcggtcttct tccaccaaac ggatacgcac aatttttttg ccaagtgtcc
    29401 atccattggt tataaacggt acaatcataa agtatacccc tacttctaat aaaagccacc
    29461 agatatgaga agtaactgcc cctgaatcga acgcaatttt aaagaaaatc gccgctacca
    29521 aattaataag agataaaaat gtccagtcga tcaaataagc gaccaagcgt cgagtcaatg
    29581 agacagtctt tcctttttca taagaaagtt catccattcg tcttcttgta ggaagcataa
    29641 atgtaaataa cggcgtaacg acaaaaccaa tgattccacc caatgtattt gtcactaaat
    29701 cattcacatc aaataagcgg tatggtcttg ggtagataaa ataaagtcca cttagctgcg
    29761 tcaattcaaa aaatagagaa aggcagaaac tagcaatcat cgttttcata aaagaaagcc
    29821 ggaaataata tcttaaataa atgccaaacg gtatgagtaa taaaacatta aaagctggtt
    29881 ccaaaaatac actctgcttc attgccggca ggtaggtact aggttcagac aagaccaata
    29941 ccgtgttgtc tctgaaatgt tgccatgaag caaataaatg cagctccatc tttggccctg
    30001 tcatttgggc aaccgtctcc tttgccggaa gtggtaagat caccaaaaaa tacgcacaca
    30061 ataaataaaa aacgaaagaa tacaaaataa ctgcccttgt tactagaaat gttccatact
    30121 ttcgatattc ataaataaaa aaaacagatg agatcgctaa ggctaaaaat ggaaaaacaa
    30181 tcagcgcaaa acgaatcggt tcgatataac ttgccatatg actcctcctt gattctttgt
    30241 atctctctta tcttagcagt cctttgctgt ttcaagcaag taacgaggct attatttctc
    30301 atttctttca aagtaaagta agataaacac aaagggggtg tcgagatgct gaatatgtac
    30361 tttgtttttg gcgtacctat ttttttactg ttcctttatg ctacgatcgc ttatgtaaga
    30421 aaaagaacta caattcatta tttaggattt attctcctga ttatttcggg tttcatgcta
    30481 gtcttcaatc ttcagacttg gcagcaagca cttcttgaaa tggataaaat gactccacat
    30541 gctttgtcta aagtgcttgg ctaccctgtc tatctgattt ggcttcccat tttcatttct
    30601 ggttgcttgg ttttattaaa tatttatcgc ggcgtacgcc gaatagttca gttacgcaaa
    30661 tcaaagtaaa agacagaaat cggttgagcc cgatttctgt cttttacttt gctatttcat
    30721 cgtagacaaa acgacattta cgtgatcaaa attaacgagt acttttgaca tttcttccac
    30781 gtactcctca tttaaataaa atattttgtt tggcagagaa gtgcagttct aataaaattc
    30841 gaatgtttta gctatctacg ttttaaatag agataaatcg ggataccagc aagtgtcaat
    30901 actatcccca tcgaagctaa aaaggtctga gtgataagcg tgcttgatac gataaaagtc
    30961 cctccaatga ttgctactag tggaataaac ggatacattg gaactttgta tggtcgaaac
    31021 aaatcaggtt cttttttacg aagaagaatg acaccaacaa agaccatcgt ataaaaaatc
    31081 caaatgacaa agatcagcat atccgttagt gtatcaaaac caccgatcat catcatgcca
    31141 atagcgatga ctagctctaa gatacctgcg gctacaggaa ctttagtttt atcatgaagt
    31201 ttagcaaaga gcttgctaaa aggcaggttg ttttcttttg ccataacata agggagacgc
    31261 attccagtaa gggtatagcc attgatggtt ccataaacag aaatcaagat accaactgtg
    31321 accagtcttc caccgaagcc gccaaaaatc atttttgcaa cgtcacttgc cgcattgctg
    31381 tttcctgcga ctccgtcgat agatgcggtt cttaagaaca ccgcatttac taataaataa
    31441 acgatcatga ttccgatgat tcctaaagaa attgcttttg gcaaatcttt cgccggcttt
    31501 ttcaattctc ccgaaatatt tcctacgtgt atccaaccgt cgtatgcgaa catcgttgct
    31561 agcaagcccg ctcccaaggc tgagaaaaat gaaagatttt ctcctgcttg gatcggaaac
    31621 agttggaagt ctactccttc ttgtcggaac aaaccgaaaa tgacgatcac aaacaaagga
    31681 ataagcttgc agacaagcgt aatcgactga aaagcccctc cagctttaga acctaaaaaa
    31741 ttgatcaaca ggatcgatac agcagctgta acagctacgg gaacaatcat tgactgggaa
    31801 agaccaaata gattgacgaa ctgtgtaccg aaaatgatcg acaaggctgc tacatttgct
    31861 ggaaaataaa tcacgacttg cgcccagccc aataaaaaag ctgctgtatt tccgtaaatc
    31921 cgttcgatat atttaatcat ccctcctgtt tctggaatag cagctgccag ttcagctcct
    31981 gttagtcctg cacagacaga aatcatacca ccgagaaacc aagaaaacat atgcaaactg
    32041 gcggatcctg taacttctgc tacgcttgcg gctttaaaaa atacccctgc accgatcact
    32101 gtgcccataa cagtcgataa agcagtaaaa aatcccatcg tacgttttaa ttcattttct
    32161 atttttactt cttttactgg cgtggcttga tattcttcca tcccttgtcc cctttcatac
    32221 catagccaat cccaaaagta taaaaaactt tttggatgtg gttcttgttt tataccgtct
    32281 ctaccaattt ttctttcagt ttttccaaca tatcctttgt catcacatct aagtcgtatt
    32341 tcggcgaaaa gccccattcc tcttgcgcac aagaaacatc tagtgaattt ggccaagatt
    32401 ctgctattga ctgacgtaca ggatccacat cataatccat ttcaaaatct ggtatgattt
    32461 tttgaataga tgctttgatc tcttccgggt caaaagacat cgccgatata ttgaaggcat
    32521 ttcgatgaac caatcgatca ggatctgcat tcatgagttt tataatggca tcgatcgcat
    32581 ctggcatata catcatatcc attgatgtac cttgatcaat gaaactagtg tactttcctt
    32641 ctttgattgc tgaataataa atatcgactg cgtagtctgt cgtaccgcct cctggcaagg
    32701 ttgcataaga aatcaatcca gggaaacgga caccacgagt atctacgcca tatttcacat
    32761 aataataatc acatagtagt tctccagcta ccttcgttac cccatacatg gttgtaggac
    32821 gctgaagagt atcttgtggg gtatgatctt ttggagtatt tggaccaaac gcgccgattg
    32881 aacttggcgt aaaaaatttc agctggaatt ctctagcgac ttccaatgca ttgaccagcc
    32941 cagtcacgtt caaattccag gctaattgtg gttttgcttc tgcaacagct gacaaaagag
    33001 cagccaaatg aatcaatgtg tccacttgat attgttctgc tatgctgcgc attttttcgt
    33061 aatccattac atctaggatc tcaaagatat cgtttttctc aatgacttca ggcatgcgta
    33121 tatctgtcgc aatgacattt tcactgccta gttcttgacg tagccgtgtg atcaactctg
    33181 aaccaatttg tcctaaacat cctgtcacca atactttttt catgatgatc ctccctgatc
    33241 ttttttacta ctatcttcag atgattaaca atatatgcgt gaacatgttc tctaatttta
    33301 aatagacgaa aaaactaaat ttagttaaat aatttccatt tcttttccta ttttttgata
    33361 aactgctact gcttcatcaa gcatttccct cgtatgttcc gcagtcggca tatttctgat
    33421 cctgcctgtc ccaagaggca cagttggata aacgattggt ttagcataaa tcccatgttc
    33481 gatcagcttc ttagagaaag tctgagtcac tttttcgtct cccaaaatga ctggagtaat
    33541 aggtgtttca gacataccga tgttatagcc tacttttttc aattcttctt taaaataatt
    33601 agcattttcc caaacttttt cgacaagttc cggatgttct tgcatcaaag taatcgaagc
    33661 caatgcagct gcagctgcac ctggagttag cgaagtagaa aataggaatg gccgacttct
    33721 agctttcaac cagtcgatta gtgttttcga tccagctaca taacccccaa caacacctat
    33781 agctttcgat aacgtgccca tttgcatatc gattttgtcg cttaatccaa aatgcttgac
    33841 ggttcctgca ccttttccag ttacgcctga gccgtgcgca tcatcgacgt aggtgatcag
    33901 tccatatttt tcaacaatcg gaataatttc cggcaatcgt gcaatgtctc catccatgga
    33961 gaaaacacca tctgtgatat acatgatttt tttatatttc ttactttcta tcgcttcctt
    34021 tgcttttttc tcaaggtctt tcatatcttg atgtttaatt cggatgattt ttgctccgga
    34081 taagcggcaa ccgtcaataa tagatgcatg gtttaattca tccgataaga tagcatcttc
    34141 ttttgtcatt actgcagaga tagcgcccat attgcagttg aatccagatt gaaaggcgat
    34201 tgctgcttct gtccctttga attctgcgat tttttcttct aattgctgat ggattttcag
    34261 cgaaccattg atcgttcgga ctgctcctgc tcctacacca taagtttcgg ttgcttcaat
    34321 acatgctttt ttcaattctt cgcgattggc aaatccaaga taattgttgg atgctagatt
    34381 gatcatcttt tttccgtcta cgatgataca agcaccattt tcactttcta gtatgtcgat
    34441 cgtattgtat aacccctttt ctttcagttg atccaattct ttctctaaat acattgttag
    34501 ttctttggaa gacattgtct ccacctccat attcatctgt cttgcagaac ataccaaaca
    34561 tatatcgtgt cattcatcta caaagcaagt atgctatatt tttgataacg cttacactga
    34621 ttatgagaat tatttaacca cattttttat ttacagtatc tttttacttt caaatgactt
    34681 atatagtatg aacaattacc ttttagataa tgatctattt tactctacct gggcagataa
    34741 atacaacaca accattgata gaagcccttt cgttaaaatc aattgtattc tgaatattta
    34801 atttatttat tgcatagacc aataaaaata cataaaattt ccatcttcgt ttatcagcaa
    34861 tttttaattt tactctctga atatttctta aaagttttac ttgttgaatt cgaaaaaagg
    34921 actgtgacaa aagtcttgtc acagtcctat tcttccgaat a
//
LOCUS       DADQDV010000024        34836 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.024, whole genome shotgun sequence.
ACCESSION   DADQDV010000024 DADQDV010000000
VERSION     DADQDV010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 34836)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34836)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34836
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.024"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..2322)
                     /gene="esp"
                     /locus_tag="J8S10_001258"
     CDS             complement(<1..2322)
                     /gene="esp"
                     /locus_tag="J8S10_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HAZ9629848.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLVGVGLVLGTT
                     ELVQAQDEISPSTPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEEPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSASAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGKKVADLAIERRKDHENYGVGSITDNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSILDVYNKDFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFT"
     gene            complement(2939..3244)
                     /locus_tag="J8S10_001259"
     CDS             complement(2939..3244)
                     /locus_tag="J8S10_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629849.1"
                     /translation="MLNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDA
                     KISSYLFFLIHDEFMDYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            complement(3389..4594)
                     /locus_tag="J8S10_001260"
     CDS             complement(3389..4594)
                     /locus_tag="J8S10_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HAZ9629850.1"
                     /translation="MFSDKEVLLKSLHVCLKLPIVVFNSEFSIIKEYRSDRTTYFFYD
                     YKKLLTDNIKKTKDFHFFTGDFNEMFLLYMFKTRYYLFGPFRANNIDKDFFKLKMNNL
                     NVAMADRERLYNSLQNLTLYSLGDIRDILILVHYFFTGKIEDLFHEPLIEYTGNLSKT
                     IEQIKIDNLLSQNYDPEIYLFLYENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGDT
                     IRSEKNYSIIVFEKLAQTSITLGMDIIEAYQSRDALIQENELAVSLPEVLKVRDSGIV
                     YYTKEIGKTKIEHLSPLISSVVQFIGLNIYKRITVKEIANYFSVSETKLRESFKNEMH
                     ITIYNYISKRKISTAKIMLKSNHTISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLG
                     LVDNFNNIS"
     gene            5288..5674
                     /locus_tag="J8S10_001261"
     CDS             5288..5674
                     /locus_tag="J8S10_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAZ9629851.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFNKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            5772..5963
                     /locus_tag="J8S10_001262"
     CDS             5772..5963
                     /locus_tag="J8S10_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAZ9629852.1"
                     /translation="MNTLKEDFILAKNGNEEAVVAILKRFSALVHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            6477..6809
                     /locus_tag="J8S10_001263"
     CDS             6477..6809
                     /locus_tag="J8S10_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAZ9629853.1"
                     /translation="MKKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            7106..7261
                     /locus_tag="J8S10_001264"
     CDS             7106..7261
                     /locus_tag="J8S10_001264"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HAZ9629854.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLTDHHITHSMSQTGTPVDNAVIE
                     AFHRSIK"
     gene            7537..8877
                     /locus_tag="J8S10_001265"
     CDS             7537..8877
                     /locus_tag="J8S10_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAZ9629855.1"
                     /translation="MSYSEFTKELLDILDLNLTFHEDAFRKERINDETCFVFDGTLTY
                     QPEECFHCHYQNKQTIIKWGWKKVSILLNDVSNYKTIVRINKQRFKCKHCGKTFLAED
                     SVSDRRCSIARRVKQAILELLSEPISMSLIARMKHISPTTVIRILRSLRPKTVSLNQP
                     LPEVVCFDEFKSVKNVSGAMSFVMMDGKTHQLIDIVENRQLNPLRDYFLRYPRKVREQ
                     VRLVVSDFYTPYRTLVKECFPNARIVADRFHISQHIGRAFTNHRIQVMKTFKKGDRRS
                     KHLKKYWRLLQKNAWELNGQHRYWRPSFRDHLTEAEIVDRLLYYDDSLKRGYEVYQVF
                     LSAIRRQDVPEFVALLKEDYKELPEHYQPVFTTFKKYRTEIKRALRVPYSNGPIECLN
                     NHIKVLKRIAYGFRNFQNYRERIFLYRGKYFKKTKNTTQLTKARTTTRLDKIAV"
     gene            complement(9118..9525)
                     /locus_tag="J8S10_001266"
     CDS             complement(9118..9525)
                     /locus_tag="J8S10_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HAZ9629856.1"
                     /translation="MKFLRKAGVKIGDVIIIGILIIPSFIPLFVFSIEKENETTEDAI
                     KYAIVQIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVR
                     TGWISKPGQTSICLPHKLVISIEKKESKDYYIY"
     gene            complement(9714..10541)
                     /locus_tag="J8S10_001267"
     CDS             complement(9714..10541)
                     /locus_tag="J8S10_001267"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HAZ9629857.1"
                     /translation="MPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGISKPIPII
                     QAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVVEEEQDI
                     RGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVDLSKILN
                     TNLFNIDETSYSMGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFAHLTDKN
                     FPGNITRAKGFLWFAQHSDFSTIFETSGSHKSIESLNYWVASLPKIECQMIIQKNPN"
     gene            10850..11068
                     /locus_tag="J8S10_001268"
     CDS             10850..11068
                     /locus_tag="J8S10_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAZ9629858.1"
                     /translation="MSQYCHLTILKRERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTNHLPKRKKIMLIEEKNADVITF"
     gene            11089..11724
                     /locus_tag="J8S10_001269"
     CDS             11089..11724
                     /locus_tag="J8S10_001269"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAZ9629859.1"
                     /translation="MVRHLFVDFQWSPEKISNRLKHEHMDFSISFITIYRAICNDLFD
                     TEPLSHGNKGLIRSLHHRGKTRHTKNHVESRGKICLTHSIHGHPKSADDRSDFGHWKA
                     DIVAGKTSGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEVLNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(11917..12156)
                     /locus_tag="J8S10_001270"
     CDS             complement(11917..12156)
                     /locus_tag="J8S10_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629860.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYQFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(12180..13703)
                     /locus_tag="J8S10_001271"
     CDS             complement(12180..13703)
                     /locus_tag="J8S10_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HAZ9629861.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLIQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKLNKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNEMHNWPTFYPASLSEHEIAQEMMAH"
     gene            complement(13721..13843)
                     /locus_tag="J8S10_001272"
     CDS             complement(13721..13843)
                     /locus_tag="J8S10_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HAZ9629862.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKQNKMKKLA"
     gene            complement(13873..14856)
                     /locus_tag="J8S10_001273"
     CDS             complement(13873..14856)
                     /locus_tag="J8S10_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HAZ9629863.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVIADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLEKFNHPLVFESDSSENH
                     YNGKHYHQHHQEHEFKSILLTSDQDIKKDFLFQLIDRLILTNQGSLYRFKGLIALQDQ
                     DFIVAIQGVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            complement(14880..15029)
                     /gene="rpmG"
                     /locus_tag="J8S10_001274"
     CDS             complement(14880..15029)
                     /gene="rpmG"
                     /locus_tag="J8S10_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003550836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HAZ9629864.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            complement(15050..15427)
                     /locus_tag="J8S10_001275"
     CDS             complement(15050..15427)
                     /locus_tag="J8S10_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629865.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            complement(15459..15638)
                     /gene="rpmF"
                     /locus_tag="J8S10_001276"
     CDS             complement(15459..15638)
                     /gene="rpmF"
                     /locus_tag="J8S10_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HAZ9629866.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            complement(15653..15922)
                     /gene="rpsN"
                     /locus_tag="J8S10_001277"
     CDS             complement(15653..15922)
                     /gene="rpsN"
                     /locus_tag="J8S10_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HAZ9629867.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            complement(16445..18217)
                     /locus_tag="J8S10_001278"
     CDS             complement(16445..18217)
                     /locus_tag="J8S10_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002841847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9629868.1"
                     /translation="MRMQMIGGLTMKSFYKNKFALTNQGAEDLVKASISSFFVYCINM
                     VPAFIIMMLIDELVLENVKPPWLYFTVSFVTLLFMYWLLDREYENLYNSTYKESAHLR
                     MQIADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVM
                     LLVGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEI
                     NSFNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLL
                     TGEVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSP
                     LKSFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDY
                     DEGCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAA
                     RLANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLD
                     AENEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKIVDQGTHSELYRRSE
                     IYKNLIKKTKLSEKFVYEKEAQSR"
     gene            complement(18171..19925)
                     /locus_tag="J8S10_001279"
     CDS             complement(18171..19925)
                     /locus_tag="J8S10_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9629869.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLK
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQHLMKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHQVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            complement(20035..20604)
                     /locus_tag="J8S10_001280"
     CDS             complement(20035..20604)
                     /locus_tag="J8S10_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HAZ9629870.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVASWALMQLGSAAGQWIPIWFFTDRFRQDWIDKGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            complement(20622..22046)
                     /locus_tag="J8S10_001281"
     CDS             complement(20622..22046)
                     /locus_tag="J8S10_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HAZ9629871.1"
                     /translation="MKELFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSG
                     KSTLLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTN
                     TTSELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLS
                     LNSKLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVK
                     NRTVKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDIN
                     FDVKVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQF
                     FTESVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSK
                     TNLFLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGG
                     IKKDIKLRVEDSTLIEQIFNDITK"
     gene            complement(22048..22716)
                     /locus_tag="J8S10_001282"
     CDS             complement(22048..22716)
                     /locus_tag="J8S10_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HAZ9629872.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFGTSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(22847..23431)
                     /locus_tag="J8S10_001283"
     CDS             complement(22847..23431)
                     /locus_tag="J8S10_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAZ9629873.1"
                     /translation="MESGLSHFEKVGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLV
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            complement(23766..23996)
                     /locus_tag="J8S10_001284"
     CDS             complement(23766..23996)
                     /locus_tag="J8S10_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010708749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
                     /protein_id="HAZ9629874.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLTKLRYEDYLDIGFQLTDKGKKFIDDYKKRF"
     gene            complement(24011..24961)
                     /locus_tag="J8S10_001285"
     CDS             complement(24011..24961)
                     /locus_tag="J8S10_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HAZ9629875.1"
                     /translation="MMRKWKAVLGSLGILIALFIFGACSTNSKDKDTVASNEKLKVVV
                     TNSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETG
                     GNAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKN
                     IEKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYF
                     SKAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDT
                     NIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(24958..25800)
                     /locus_tag="J8S10_001286"
     CDS             complement(24958..25800)
                     /locus_tag="J8S10_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HAZ9629876.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVTVVLFFKELLIT
                     SFDPLMAKAMGMNVSFYHYLLMILLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGACSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERKL"
     gene            complement(25933..26658)
                     /locus_tag="J8S10_001287"
     CDS             complement(25933..26658)
                     /locus_tag="J8S10_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HAZ9629877.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKELKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGEGGTA"
     gene            complement(27119..27433)
                     /locus_tag="J8S10_001288"
     CDS             complement(27119..27433)
                     /locus_tag="J8S10_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HAZ9629878.1"
                     /translation="MHKDLLIICETGISASLLVSKMLETIRAKNLSYEIDYATIRNVE
                     EKLNYKDYDVLLLTPQVARSEEKVKEIIKKEKCTAQIVYIKQEDFRYMNIENIIASIE
                     ED"
     gene            complement(27449..29044)
                     /locus_tag="J8S10_001289"
     CDS             complement(27449..29044)
                     /locus_tag="J8S10_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="solute:sodium symporter family transporter"
                     /protein_id="HAZ9629879.1"
                     /translation="MNLFSIISFLVIVICVWLFAYSRSRSVDTSGSEGFFMGGRSLTA
                     LPIAGTIIMTNLSTEQIVGQNGQSYHAGMEVMAWEVTATIAIVALAVIFLPKYFKYGI
                     NTISDFIEIRYDTVTKRIISILFIVTYMTSFLPVVLYSGSLVFNKIFHIDELLGVQPI
                     VAIIIVAMAIGIVGILYLLIGGLSLSANSDSIYGVGLLACGLLVPILGLMKLGDGSFV
                     GGIEHVVVNTPWLLNSVGSIDSAVVPWPTLFTGMLFNNLYFWCTNQMIVQKALSGKNL
                     AEAQKGAFLVGVFKILGALFLVFPGIVARNIFGDSLMSNPDNAYPFLVSEVLPKMIFG
                     IFAAVIFGAILSSFAGALNATSTLFSLDFYKPLINKKANDKQIARAGKTVTVVVGIIS
                     IIVAPFISFAPAGLYQFVQEFNGLYNMPLLVIILFAFYSKKATAFGAKTTIAVHIVLY
                     ALSKMLFQNIHFLYVLTALFVLDIIILMVVSKLKPDGEFVLNSFDTKVDIEPWKYTKV
                     TAIALVVIVILTYVAFSPIGFAG"
     gene            complement(29067..29957)
                     /gene="iolE"
                     /locus_tag="J8S10_001290"
     CDS             complement(29067..29957)
                     /gene="iolE"
                     /locus_tag="J8S10_001290"
                     /EC_number="4.2.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015076872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="myo-inosose-2 dehydratase"
                     /protein_id="HAZ9629880.1"
                     /translation="MTKQIQLAIAPIAWTNDDMPELGSENTFEQCISEMALAGFTGTE
                     IGNKYPKDPEVLEQYLNIRGLKVASAWFSAFLTTKPFEETAEAFKAHRDFLHAMGAKV
                     IVVAEQGHSIQGIMTAPVFDDKPVFTDEEWKKLAEGLEKLGDLAHEKDMEIVYHHHMG
                     TGVQTTEEIDRLMEMTDPDKVKLLFDTGHLVFSGENPIAVYNRHQDRIKHIHFKDIRQ
                     ETAEEVEKEKDSFLNGVKKGVFTVPGDGMIDFTPIWTAIHASDYEGWIVVEAEQDPAK
                     ANPFEYAVKARSYIREVTGL"
     gene            complement(29974..30999)
                     /gene="iolG"
                     /locus_tag="J8S10_001291"
     CDS             complement(29974..30999)
                     /gene="iolG"
                     /locus_tag="J8S10_001291"
                     /EC_number="1.1.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol 2-dehydrogenase"
                     /protein_id="HAZ9629881.1"
                     /translation="MNNIRVGIVGLGRLGKVHAQNLATGVSCCELTAACSLVETELAF
                     AQKKLGVKHTFSSYEEMVKSSVIDAVFIVSPSGFHCDQVRLAMENGKHVFTEKPLGLE
                     VEDIKKTQKVIEEHPEQVFMLGFMRRYDESYQYAKKMVEDGEIGEITLIRCYGIDPSE
                     GLESFVKFAMNNDSGGLFLDMAIHDIDLVRWFTGQEVDQVWAIGKNAAYPELDQAGEL
                     ETGAAMMSLSDKTIALLVAGRNAAHGYHVETEIMGTKGMLRVAQAPEKNLVTIMNDQG
                     IIRPCSQNFPERFREAFIREAQEFVSCIQEKRQPAVNAEDGLQSTKIALACQESFDTK
                     SLVQLKK"
     gene            complement(31023..32030)
                     /locus_tag="J8S10_001292"
     CDS             complement(31023..32030)
                     /locus_tag="J8S10_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016634067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAZ9629882.1"
                     /translation="MRVKVGVIGTGAIGIEHIDRINQKTQGAYVTAVSDINVKAAKEV
                     AKRVDAKFFETGEALIASEDVDVVVVTSWDPTHEQYVLEAIKHGKYVFCEKPLAMDAA
                     GCRRIVDAEVAYGKKLVQVGFMRRYDRGYIELKEAIESKQYGEALMMHCAHRNPSADE
                     NYTTPMAISNTAIHEIDVLRWLLNEDYESVQMILPKKTSNSHADLHDPQLLIFQTKSG
                     VTIDLEIFVNCRFGYDIKCDVVFETAEVGMTDPAYTRIKSEEKNYTPVSPDWQTRFLD
                     AYDYEFKLWIDSIKNDAVVGPTAWDGYVAAITMMACHESRETKTKVMIQMDERPALYN
                     E"
     gene            complement(32143..33303)
                     /locus_tag="J8S10_001293"
     CDS             complement(32143..33303)
                     /locus_tag="J8S10_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HAZ9629883.1"
                     /translation="MNIQLKMPANLRIGGGTIQFLMEESEQLGNKPLIISDTVMEQTG
                     HLQKIKELLGKTDDQLAEYTDIQAEPTQENVYDALKLFQKHQCDHIIAFGGGSCLDTA
                     KVVAVLAANQLSLEAIHARNFDQLQAGIPLIAVSTTAGTGSEVTDVAVITNTKTAVKM
                     MMKDLVFMPQISIVDSDFTKTVPPKVTAATGVDALCHALESYVSVKANEVTQLFSLEA
                     MKKILNTLSQAYENSDDTEAREQMSLASTEAGIAFSNASVTLIHGMSRPVGALFHIPH
                     GISNAMLLPVFFEFSKDAIQTELATIARFIYPAAEDLSLEEAADYLIKKIQELCEQLS
                     IPTIRDYGIDQQAFMAALDKMAADALTSGSPQNNKKVPSHSQIKELYVQAYG"
     gene            complement(33379..34833)
                     /locus_tag="J8S10_001294"
     CDS             complement(33379..34833)
                     /locus_tag="J8S10_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010825391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-acylating methylmalonate-semialdehyde
                     dehydrogenase"
                     /protein_id="HAZ9629884.1"
                     /translation="MTRFLRNYIDGRWVASRSTEFEEVMNPATEEALANVPLSSKAET
                     AEAVKAADAAFQTWKKVPVPVRGRYLFKLHQLLTDHKSELARLITLENGKSLSESLGE
                     VQRGIENVEHAAGITNLMMGDSLSTAATDIEITNYRYPIGVIGGITPFNFPMMVPFWI
                     FPMALAAGNTVVLKPSEKTPLLMEKIVELVEKAGFPSGVFNVVYGAHDVVNTLLQDPL
                     VKGISFVGSKNVGEYVYREGTKNLKRVQALTGAKNHVVVLKDANIDRAVKDLIGGAFG
                     SAGERCMAASVIVLEEEIADQFVEKFKAAAKAIKIGNGLDEGVFLGPVIRKDAQQRTF
                     DYIQKGVDEGAKLVLDGRENIPEKGYFVGPTIFDNVTMDMKIWQDEIFAPVASIVRVK
                     DLMAAVELTNESEFANGSCLYTNNASAIRYFRENVDAGMLGVNLGVPAPMAWFAFSGW
                     KHSFFGDLHANGKDSVEFYTHRKVVTARYAQSEI"
BASE COUNT        10898 a         6941 c         5335 g        11662 t
ORIGIN      
        1 ggtgaaggtc actttgtggt agcctgcagg aatgttttct cctggatttt cataaatatc
       61 tttacttaca gttactgcta aatcggtcgt gcctacagaa ccatcttggt aaacaatttt
      121 aataggaatt gttccagtaa tcggctccga ttctcctaca cctttagctg gagtgaatgt
      181 aacaatacca gtatttgcat caacacttgc attaccgaag tccttattat agacatctaa
      241 aattgaaaag gcatctttag ctaaaggaac atctggttta tcaaatgtag gttttccact
      301 ttgaactgtc gtttctggag ttgttgttat aggtacgtat gttgcatcat tttccatagc
      361 ttgagaagct tttacagcaa actctacatc cacgtcgaaa gttcgatttc cgatcttaac
      421 agttacaata cctttcgtac tatcagtaac gttagaagta tcaggctctg ttttccatga
      481 atactctgca tcttcaggta agtttttatt attccgaatt gattctttag catctggttt
      541 aaatccaact accacggttt gtttatcaac cgcttttggt gattccttaa taacggttga
      601 accttcttct ggtttatcaa aacctggaga aacgatttgg atttttaatt catctttcgc
      661 gattaattta cttgaatcta cacccgtaaa ttcaaattct acagtatctg aaattggagc
      721 cccatctttt tcatttggag cgatagtttt ttctgctaat acagtacctt ctttatcaac
      781 aagttgggct ttgtgacctg ttcccgctaa ctcgtggatg aatactttcc ccttaactgt
      841 tgtgtcaaca tcatatactt cttctaattc aggtttcccg atatatggat tcgtgtctcc
      901 gctctcttct ttatcgtcag ggtttccatc accatcaata tcttgcaaat aataataacc
      961 tgttccataa gtgttctgga ttaatttttt attcgtatcc gacaaccaag aatcaaagat
     1021 gaaatcttca ccaaatggtt tattttcttc aacttgtgct gttgctttca tatcttctaa
     1081 gatttcatct aatggcttag tcaattgtaa aacatatcga ataacgactg gacgtggact
     1141 tgcattagca aaatcaataa gtttggtaag atcattatca gtaattgaac ctacaccata
     1201 attttcatga tctttgcgcc gttcaattgc taaatcagcc acttttttcc ctgattcaaa
     1261 agaaacatca tatgttactt tgtcagcctg aaccatgtgc atctgtatac ccgctacata
     1321 tggaactaat cgttcatcaa ttttgtaatt agcataccaa ggcgtgccct ttgcggaagc
     1381 tgaatatgag aaattataat ttttcgttaa cttatgatct aagattatag ctccattagc
     1441 acctgtggat cctgaaccat cttttgtttg agtattaggt tcctcatatt ttgcacttac
     1501 tgatccatgt ttaaactggt caggattatt ttcagataca tctaagctat tatagaaatc
     1561 atctgaatct gttaaaaagt agcccgtact atcaatacct ggtacaattt tatcatcgtc
     1621 ttgatgactt accaagtaga ttcgatacat taaacgatcg gtcttgagat tgtctatgcc
     1681 tatctcttta aaaatttcat ctaagctctt ttcaaacgta attaccccat taggagcagt
     1741 ttgtgtatca gttgtttcag ccccagcaaa taatccatca cttgcacgaa tataattgac
     1801 cttccaaata tttgtaggtc tacccagcga atcattaatt cttacaaagg tccgtctaga
     1861 agatccaatt cctttctttg gatcgacctg aattttttct acatatttag ctaatcgttc
     1921 atctaattga agacggattt cccagttttt agttgatgct gcaatattat gttttccgta
     1981 aacttcaaat ccaattgtat tgccttttag tgtgtctcca gttagttctt gaggactaaa
     2041 ttgtaaatcc gaaaagttat aatttttcgt ataaccagga ttctcctgaa aagtattccc
     2101 cgaagctact ttgtcaccta cttgtacgga gcttatcgct gtttcaagtg gggtgcttgg
     2161 agaaatttca tcttgtgctt gaactagttc agttgttccc aagacaagac caacaccaac
     2221 caaaacagat gcaaccccaa cacttaattt tttgatactg tacttcaata ctcgtttctt
     2281 tgttttttct agaaatactc tcttattatt cttgctaacc attattcaaa tcaactccct
     2341 taatagttat tttcttagta agaataaaag ataaatctga tacgtattat tcacagaata
     2401 ggaatcttac taaacttatg ttaactagtt tacttaaaga atttcatgca cattacaaca
     2461 aaaaaagtac atttcttcat gtttttttcg gatatttgtg ctttttaacc attcagcagc
     2521 tgaaaacata taaaaagata tgtatgtatt ctttctgaaa ttaagttcat ttctatgcga
     2581 tgaagcatgt tttcaaaata ttactctttc ttagattaaa cttcagagta ttcaaatagc
     2641 ggaataagga gccttatccc gcattactga atgagactgt gacataagta aaaaggtgac
     2701 ttcaaattcc ttcttcggaa tttgaaatca ccttctttat aattataaag tatcggtttc
     2761 acagcattcc tgaatgattc ctagaatctt aaacgaatga ttggagttat caacattttt
     2821 tcactcgttt ttagcgaaac aaaaaatgac atttgtcaca gcctcattaa attattgatt
     2881 ctttttcttt ataattgaat tgtccatatt taaagtgtct agtactctac atgaataatt
     2941 aattgctttc actcaaatac ttataatcta ttaacttgta gttgtttaac ttttctgaaa
     3001 aagttagacc cacgtaataa tcttcccagc tttctctttc aattaactga tccaattttt
     3061 gataatccat aaattcatca tgtattaaaa agaataaata acttgatatt ttagcatcta
     3121 gcttaatcag attaaataat gtttgcttaa aattgctacc attaatatga ctgatagatt
     3181 ctctagcttc ttcacataaa ctttttactt tattaattac tactttgtca tattcattta
     3241 acacactatt attaccatta cttagacgct cagattctac gaaacaactc aaatcagaaa
     3301 tttcccaaaa aattttttgt taaaatccaa tttcctcaac tcctccaaac tacgtaaatg
     3361 atatagtctc ataataaaat aaaacctctc agctaatgtt gttgaaatta tccactaaac
     3421 ctaattgata ttgcttagga gatacacctg cgtacttttt gaatactctc gaaaagtgtg
     3481 aagaatctga aaatcctaaa cctaaagaaa cttcactgat agtatggttt gatttcaaca
     3541 ttattttagc cgtagaaatt tttcgcttag agatataatt ataaatcgta atatgcattt
     3601 cattcttaaa gctttctctt aatttagttt cacttacaga aaaataatta gctatttcct
     3661 ttacagtaat tcttttatag atatttaagc cgatgaattg aacgacagaa gaaattaagg
     3721 gagaaagatg ctctatctta gtttttccga tttccttagt ataataaaca atcccagaat
     3781 ccctcacttt taagacctca ggtaacgata cagctaattc gttttcttgt atcaaagcat
     3841 ctctactttg atacgcttct attatatcca ttcctaatgt tatagacgtt tgtgctaact
     3901 tttcaaaaac aatgatagaa taattttttt cagaccgaat cgtatctcca ctaacacttg
     3961 gaattattcc attactcaga ttaaaaacca tgttttctaa atttcgaata tctccatttt
     4021 taacatattc cagtatttta ttttcataaa gaaacagata tatttctgga tcgtaatttt
     4081 gtgataacag attatctatt ttgatttgct cgatagtttt acttagattt cctgtatatt
     4141 caattaacgg ttcatggaat agatcttcta tttttccagt aaaaaaataa tgaactaaaa
     4201 tcagaatatc tcgaatgtct cctaaagaat acaaagtcaa attttgcaat gaattataga
     4261 gtcgttctct atcagccatt gcaacattca aattgttcat ttttagttta aaaaaatctt
     4321 tatcaatatt atttgctcta aatggaccaa ataagtaata tctggtttta aacatgtata
     4381 gaagaaacat ctcattaaaa tcaccagtaa agaaatggaa atctttagtt tttttaatat
     4441 tatcagttag taacttttta taatcataaa aaaaataagt agttctatct gagcgatact
     4501 cttttataat actgaattcg gaattaaaaa ccacgatagg taactttaaa caaacatgaa
     4561 gagactttaa taagacttct ttatctgaaa acacttttgt ttctctcttt cctttctaca
     4621 tcattaaata gtattttata cgttatctaa aatactattc ctctgtcaaa ataagctaac
     4681 ttacttcatt ataaaatatc cacttatcgc tttcatgtat attccaccgt aaaaagtaca
     4741 ttttatcacc gagaactcat catttttcat catgatgaat actatttaca tatatctagt
     4801 tcaaagacaa taattattat gatccgttat tatctaagca ctatacagat aataggaatt
     4861 tttcgtttct aaatactcca atttgggaat ccaataaaaa ttttcgttca aatacgtgtc
     4921 tattcgaact cttttctagt tgttaattat gaagggggaa gaaataaaaa atacaatcta
     4981 tacacgaata agaatattat ccaaaaggag gttttagaaa agatttatta tacgtaaaaa
     5041 gctcaagaca ttttcttagc cataaggaca tgtttgatat ttaagaagat atatgaattt
     5101 tcttttctaa gtataaagat aactatccat tatcaactaa aaaaacattt ttgaaaataa
     5161 acatcagcag tcctatcaat gcatgtgagc ttatagaagt tattcgcagc gcagcataat
     5221 tgcattagct tcttttcgtg ttttttgcct cttttccctt taaatcttaa tggaggaggt
     5281 gtgcaatatg tcagataacg acgaacgcgt aaatgcccag ttgattcgat tctttgaaaa
     5341 ggtcattttg aacaccgcta atacttatta taaaaaacaa gaagaaattc aaaaacatga
     5401 acaacttgat caactcccac catatttgtt tactaaagat actataaaat ttaaacaacc
     5461 gattaatgtt ttaaatgtga ctctccttgt tgaagatata aaattagcaa aaatccttcc
     5521 tttgttgaaa gaacctgaac aaatttttct tatcgaaaaa tttatcttta ataaaactga
     5581 taaagaaatt ggaaaggttc tgggtattac aagacagggt gcgacaaatt taaaacatcg
     5641 actttacaaa aaaattcaaa aaatgctggt ttaatatctg cataataact aattttgtat
     5701 gcttctttgc tcgtcctcct ccttccccaa aaaataaata gattataagt tcatgggaag
     5761 aaggtaaatt tatgaatact ttaaaagaag atttcatttt agcaaagaat ggaaatgaag
     5821 aagcagttgt ggccattctc aaaagattta gcgctttggt ccataagcaa tcctggagaa
     5881 ctggaaaata tgatcaagat tgttatcaag aatgtatgct tgcaatatat ctagctatct
     5941 cgaaattcga aattaaagaa taactcaact aagggagtct gtgacataag taaaaagata
     6001 gtttcaaatt tcgaacaata aatttgaagc catcttcttt ataattataa agtatcgatt
     6061 ttacagcgtt ctataatgat tcatagaatc taaaacgaat gattttaatt attaacgttt
     6121 tttaattcgt ttttagctta aaaataactt ttgtcacagt ctcactccta aaattacttt
     6181 atttacgtac gaagtgggca ggaggtcgaa tccagaactg ggccatggta cttcaacgag
     6241 gacttctcct ctagaattga aaagcatgcg atttaccttc cgtaacgacg gtagatttat
     6301 tcaactatgt gtccaatcaa aatttgtctg atttcaaaaa tagtcaagag aattttggtt
     6361 gttaaaaact cttatctatc aacttccaca gtttagttga caaaccctga tactaagttg
     6421 ggctatgata cacttttctt gactatcagt tacgttaccg gaaggaatga actctattga
     6481 aaaaaacata tgatcgtaaa tttaaactaa agatttcaca ggatatcctt gagaaaaaag
     6541 taactaccaa gaaaattgct gaagaataca atatctctcg tccaacaatt tcccgatggg
     6601 tttcagaata tcgtcgatac gggaaaaatg cttttgctgg acaaggaaaa agattacctg
     6661 ataaagcaga tttctacatt cttgaacagg aaaataaacg actaaaagag gaagacgagt
     6721 gttctacgaa cacaaagatc gatacggatc tccagggatc actcaaaaac tttacgatga
     6781 aggaatcgaa atcaataaac gtgttgtagc tgttcttatg cgtgaaatga atttatgcac
     6841 aagaggattt catcgacgca aatcttctca tggtagagaa aaaacaatca aagaaatggt
     6901 aaaaaaaatg ttgaatcgat aatttgaaca gaaccaaatt gatgctgttt gggtgacgga
     6961 tattacttac attccatgta atgacggtcg cctctatttg tccacctata ttgacttagc
     7021 aactcgtatt ctacgttact atatggtgga ttcacacatg aaaaaagaga ttgtcgtccg
     7081 tccattacaa atttattaag gagaattgcc tacggtaatt cattccgata gaggtagcca
     7141 gcatcggtct tttatttatc aagagctgtt gaccgaccac cacatcacac attcaatgag
     7201 ccaaactggg actcctgttg acaatgcagt aattgaagcg tttcatcgat caatcaaatg
     7261 agaattaatc gactccaaca aatataaaag taaaatagag atgaaggtgt taatccaaga
     7321 ttatttagaa gactactacc caaacaaaag aatccataca aaatttatga tgactccttg
     7381 acaatttgaa gcgaagaaaa taagggatct ataatatcta gtgttggtga cgccttctgt
     7441 tgccaatact ttttcttttt tctaataaac gcaaacagac accttgaaat cctttagaat
     7501 aaagtcgacg aaaaccattc aaaggagtgt ttcaagatgt cctattcaga gtttaccaaa
     7561 gagttactag atattctaga cctaaatctt acctttcatg aagatgcctt tcgcaaagag
     7621 cgcattaatg acgaaacatg ttttgttttt gatggcacat tgacctatca accagaggaa
     7681 tgcttccatt gccactatca aaataagcaa acgatcatta aatggggctg gaaaaaagta
     7741 tccatcttat tgaatgatgt cagtaactac aagaccattg tgcggattaa caaacagcgc
     7801 ttcaaatgta aacactgtgg aaagactttt ttagcagaag attcagttag cgatcgtcgc
     7861 tgctccattg cccgcagagt caaacaagcc attcttgagc tattaagtga gcctatttct
     7921 atgtctttga ttgcacgtat gaagcacatt tctccgacca ctgtcattcg aatacttcgc
     7981 agccttcggc ctaaaaccgt ttctttgaac cagccgttac cagaagtggt gtgtttcgat
     8041 gaattcaaat cggtgaaaaa cgtctcggga gccatgagct ttgtcatgat ggacggcaag
     8101 acccatcaac tgattgatat tgtggaaaat cggcaactca atcctttacg cgactatttc
     8161 ttgcgctacc ctagaaaagt ccgtgaacaa gtacgtctag tggtttcaga tttctataca
     8221 ccctatcgca cattggtgaa agagtgtttt ccgaatgccc gaatcgtcgc cgatcgcttt
     8281 catattagcc aacacatcgg tcgggccttt accaaccacc gaattcaagt aatgaagacc
     8341 tttaaaaaag gggatcgtcg gtcgaagcac ttaaagaaat actggagact acttcaaaag
     8401 aatgcgtggg aattgaatgg tcagcatcgc tactggcgtc cgtcatttcg agatcatctg
     8461 acagaagcgg agatagtcga tcggctatta tattatgatg actccttaaa gcgaggctac
     8521 gaagtctacc aggtttttct ttccgctatc agaagacaag atgttcctga attcgtcgcg
     8581 ctcctaaaag aagactacaa ggagttgcca gagcactatc aaccagtgtt cacgaccttc
     8641 aagaaatatc gaacagaaat caaacgagcg ttgcgagttc cctattccaa cggccctata
     8701 gaatgtttga acaaccatat caaagtacta aaacgaattg cctatggctt tagaaacttt
     8761 caaaactacc gagaacgaat ctttttatat cgaggaaaat atttcaagaa aactaagaac
     8821 actacccaac tgactaaagc cagaacaaca acacggctag acaagatagc tgtctagccg
     8881 tgtgagtatc tcgattattc tattgaattt cttcaccaac actcattgac gaagagccaa
     8941 aataagtaat ctaaccgact gttaactaaa ccattgcagg tcccgttaaa gatacttgtg
     9001 cctgttgtca ccgcttcttt ttcttgtcca caagcgctta acacacttaa taaagcccct
     9061 gctattatta ataataatat ctttttctta ttaaaaacct cctcatctat ttccagatta
     9121 gtaaatgtag taatctttgc tttctttttt ctcaatacta ataactaact tatggggtaa
     9181 acaaatactc gtttgaccgg gttttgagat ccatccagtt ctaaccgcga tttgatcagg
     9241 actattatct tctttaactc gaattcttcc atctttaatc tcaacaatat tatattgtcc
     9301 cttcgcagga tgataattca cgagtttatg attgatctta tccaaatcga agcgatccat
     9361 ttccttgcca tcaatttgaa cgatggcata tttgatagca tcttcagttg tttcattctc
     9421 cttttctata gagaatacaa ataagggaat aaaagaggga ataatcaaaa tgccaataat
     9481 tatgacatcg cctatcttga caccagcttt tcttaaaaat ttcattaacg atatctggct
     9541 aaacatatta gaatttttcc atggaaatgg tgaaattttt cggaaattat ctgcattaag
     9601 agaatcagtt aaacaaccct caagttgttc cttaatacat tgttgatcca tcttcatacc
     9661 aataaaaact agtttattaa tgcgttcacc aaacaacgga tgccaggctt ccttcaattc
     9721 gggttttttt gtataatcat ttgacactca attttaggta aactagctac ccaataattt
     9781 aatgattcaa tacttttatg gctacccgat gtttcaaaga tcgtcgaaaa atcactatgt
     9841 tgggcaaacc aaagaaaccc ttttgctctt gtaatattgc caggaaaatt tttatccgta
     9901 agatgggcaa atttttgtgc gtcaaggagt aaccgatttc gatagataaa acttgagata
     9961 ccatattctt ctgtttcagg aatatgattt tgatagccaa gctctaactc tttgaaccag
    10021 cccattgaat aggaagtctc atctatatta aaaagatttg tatttagaat tttcgataag
    10081 tctacttcac ctttaattgt cctaattatt ttggcattgg actgtaactt agcaattaga
    10141 ccgttaattt tgtaaatcgt cttggttgac actaagtcac tattatttaa aagtaatatg
    10201 ttacaacact cgaattgatc aattaacaag ccacgaatat cctgttcttc ttcaactaca
    10261 ttaccttcag cttttctttc ctgaatcttt tcacccgttt cgaaattatc ccaaaaacgt
    10321 tttacatcca ctactataat aatggcacca atctctaatc gttgggtcaa atcaatgtct
    10381 aaagggtttt tagctaatat aattgcttga ataattggaa ttggtttgct gattcctgaa
    10441 gcttcaataa caatttgatt caagtcagaa aattgcacta attgatctag ttcaacaatc
    10501 aaatcttcgc gtaatgtaca acaaatgcat ccattcggca tcgaaacaag tttttctcca
    10561 gttcttttaa aacctttctt gtcgactaat accccatcaa catttacttc ccctatgtca
    10621 tttacaatga cagcaatttc ctttccgtga tcaccgtaca gaatatgatt tagaagtatc
    10681 gtttttcctg aaccaagata gccagttaag attgtaatag gtattttttc atagggaacc
    10741 tctttctata ccttgaattt acactttaag tgcaacacat aaaaatgagt cataatcgat
    10801 atccaactag tataagtttg tcgagaacac tcctagaagg aaaataatta tgagccagta
    10861 ttgtcatctt actatactca aacgagaaag aatctttctg cttcacgaag aaggattttc
    10921 tattagtata attggcaacg acattcagca tagcccgttt actattttac atgaactgag
    10981 aagaaacaag aaaaaaacta atcaccttcc aaagcggaaa aaaattatgc ttatcgaaga
    11041 aaaaaatgcg gacgttatca cattctaaat gatccgtgag tttggtcaat tgttcgtcat
    11101 ttatttgtcg attttcagtg gtcgccagag aaaatctcga atcgtttgaa gcatgaacat
    11161 atggactttt caattagttt tatcacgatc taccgtgcaa tttgcaatga tcttttcgat
    11221 acagaacccc tctcacacgg caataaaggc ctgatccgtt cattgcacca tcgaggaaaa
    11281 acaagacata caaaaaatca tgtcgagtct cgtgggaaga tttgccttac tcattcgatc
    11341 catggccatc caaaatccgc agatgataga agtgattttg gtcattggaa agccgatatt
    11401 gtagctggca aaactagtgg tacttgttta gtgactttga cagacagaaa atcatgcttc
    11461 cttttagcag gaaagaaggt ccccagaaag aaagccgctt atgtgagcga gaaaatgatt
    11521 gaacttttaa gcagtattcc aaatgaggcg gtcaaaacga tcactccaga tagaggaaaa
    11581 gaattctcca atcatttcgc agttacagaa gtattgaata atatgccctt ttattttcca
    11641 gatcctcatg cccttggcaa caatgaacaa attaaaatac gaatagactc attcgagaat
    11701 acttgccaaa atcgaaagag atagctacgg tagataactc aacgataaat cagatgattg
    11761 aaaaactgaa taacagacct agaaagtgtt tagattggag aacaccttat gaagtcttct
    11821 ttgataaagt gttgcgcttg atttgacaat tcaagaaata ataaaaagca gatcaaatcc
    11881 aaataaggga aaaatgatct actctggtat tatcaattaa ttggccaagc tattatgccg
    11941 ttttgctaaa cgtctacttc ttccagtatt gaccttgata aaacaacaat caggatcccg
    12001 ttttaatact ctatgaactg tgtcaatact aacatgtaaa gttgcagcaa tatcagctaa
    12061 tgtactccca tttaatctca tttgctttgc aaattgataa cgccgataag catcaatatt
    12121 cttggaatcc atagacaata atacttttct taccatgtat ttcctccaaa gattggattt
    12181 taatgggcca tcatttcttg agcaatctca tgctcagata atgaagctgg atagaaagta
    12241 ggccaattat gcatttcatt ataaagtttt tcttgacttt ctccaccaaa gaaaatatgg
    12301 aaatgctctg ccttacttgg tgcaattcca tgatcgctaa attgaatata tttaaaacga
    12361 ccagcacctg catcatcagt ttcaaaatta aaacgaacac cacggtttcc tttttcataa
    12421 ttcaaaattt tgtatccaac atatttgtat gtgtattgat gatgttcacc gttgactaca
    12481 aaatcaatgg tgttgtcttt aatgttgata gtatcaatat ctgtcttata gccagtagta
    12541 taataatctt tgtactcggc agctgtcatg tctttattga gttttgcttt gtaatcgaaa
    12601 acttcatcca aaattccatc ttttaacaac ggataaacag attgccattc gcctgtataa
    12661 tcactcaatt cgcgatcctt cacatcggca tctttaaagt acccattagc aactgtcttt
    12721 tcatccttcg cttctttttc tggaactacc tcttcaccag caaccatagt tgttttctct
    12781 aacgctttta gattgtcttc cattactgaa acataatctt caccattatc catttgttct
    12841 tttgtaagac tttcaagagg attcaatact tccaatttta tcccagcttc attggccaaa
    12901 gtttttgcga ttttatcatt agcattcttt tcaaagtaaa tataattgat cttatttttt
    12961 ttaacatact cttttaattc agctaatcga ccagaagatg gctcttcttc aggacttagt
    13021 ccagcaatag gaacttgtat caatccataa tccaaagcta aatatccaaa ggctgcatgt
    13081 tgtgtcacaa aacttttttg tttcgcttct ttaagactag tggtatagtc agcatccaac
    13141 cgtttcagtt tagtcaaata cttttcagca tttgtctcaa atacttttgc ttttttcgga
    13201 tacaatttaa ctaactgatc cttgatattt gaaacttcct taattgccat tttgggtgaa
    13261 acccacgtat gaggatctag ttcatgatgg tgatcttctt ctccgtgatc atgatcttct
    13321 tcttcactac ctggcaataa aatcatgtct tttgttcctt ctactacatt aggcccagct
    13381 ttcttccaac tttctttagc ttttggtacc catgattcca tgttttcgtt atgatataca
    13441 aaaacatcag catcatgagc ttttgccata tccttagctg agggctcata gtcatgaggt
    13501 tctgatcccg ctggaaccat taaatccacg ttcgcttcat cgccgacgat gtttttggtg
    13561 aaatcataca ttggatagaa tgttgttaca atttctaatt ttccatcttt atcattcgat
    13621 acttttgcat cattagtgct ggagcaagct cccaataatc ctagagctgc tatcccaata
    13681 agtcctacac tgattttctt cattcttttt ccttccttaa ttatgctaat ttcttcattt
    13741 tattttgttt atgttctttg ataattttta atgccctttt tctagttttg atattcgggc
    13801 ttttaagtcg tcgatatgca ctagatatat ccgttttctc cattagaaat tacccctaat
    13861 caatacttat cattatttgc tttccgccag taatttatca aaactctgtt tgatcctttc
    13921 ttcatccaac atttttccaa ttagaataat agtggtttgg tctttttgtc gagtggtgta
    13981 ttgaaaatta acctgttcgt ttaccccttg tatggcaact ataaaatctt gatcttgcaa
    14041 agcaatcaat cctttaaaac gatacaggct cccttggttg gttaaaatca gccggtcaat
    14101 taattggaat aaaaaatctt tttttatgtc ttgatctgaa gttaagagaa ttgatttaaa
    14161 ctcatgttct tgatgatgtt gatgatagtg tttgccatta tagtgatttt ctgatgaatc
    14221 actttcaaaa actaagggat gattgaattt ttccaaatta taaaaatcct ttttttgaat
    14281 cgtttcacta tgtgtgaaca ttcgaatatc ggataaaggg ttaatacttt tgatttctct
    14341 ctgtaatttt tttagtgcag ataaattcaa gttttgtttt ctagacacaa aaatgcgatc
    14401 tgctatgaca agttgcttaa gggcttgtgg ttctctttca ataagttcaa aactgtcact
    14461 atcaataaca gtcaataaac tatcgatata tactcttcct cttagttgag gcgctgttaa
    14521 aagtgtttga atgattggtt ggggatctgc tatacctgta gtttcaatga tgatttgtga
    14581 aattggttgt tgatgttctt ctattgtttc cagtaaagaa atcaatattg ctaataaatc
    14641 actgcgaaga ctgcaacaca tacatccatt atttagttgt aacacccgtt cctcgctatg
    14701 aactaataat ttgtgatcaa tcccaacttc accaaactca ttttcaatta taataatttc
    14761 ttccctgggg tagggtgaga cttgcaaggc ttgattgatt agcgttgttt ttccagcccc
    14821 taaaaaccca gaaacgattg taactggtat gcccattttg tcaccttttt accacttagc
    14881 tatttcactt ctttgaaaat tgcccgtctg cgcaattttg gcgaatactt ttttaattct
    14941 aaccgttcag ggttattccg tttatttttg ctggtgagat acagacgttc tccagtttcg
    15001 acacattcca aaataatatt ttgacgcata aatcttcctc cttcaatact tatcgatctt
    15061 caagatatgc ttgaatttgt tgtgcatctt caaaagttaa ctcgccagat tccaattgtg
    15121 aaactaaatt ttctttcata tcaacaggta tctcccaata accatcaata cattgaaata
    15181 actcctcgtc atactcttca aaaattggat agattcttaa aaaatcatca aatgataagc
    15241 cttggtcctc atagtaatct ttgactaatc cattttcaat tgcctgttgg gtcggtaaac
    15301 ccgtttcagt aataattcct ctctctacca tcgaacgata aaaagtgcat ttatctagcg
    15361 attgctgggt cgtttcaaga taatacttta atccttcttc aactaaaggt gggtaaataa
    15421 tttccatttt gattccctcc taaaagttat atattaaact attttgaagc tcctttaatt
    15481 actttctttc cattatagta cccttttaaa gatacatgat ggctacgtct ataatcacca
    15541 ttcgcttcgt caaatgaaat ttctggtttt actacagttt gatgagttct tcttaaccgt
    15601 ttcttcgcct tagatgtttt tcttgctggt actgccatga tatttcctcc ttttaccaac
    15661 ttgctttttt tactccagga atcaaccctt gatgggcaag ttctctaaac ttaatacggg
    15721 acataccgaa ctttcgcata taccctcttg gacgaccatc cgtctgatca cgaagcctca
    15781 gacgattcgg atttgaatct cttggcaatt tagcgagagc ggtgcgatct cctgcggctt
    15841 ttaattcctg acgtttatct gcgtactttt caatcatcgc catttgtttc tttgctttag
    15901 caattttcga cttttttgcc atataccttt atactccttt tattttgatt tagacatctc
    15961 aaatcgtaat cgttacgttt tgacactgat actttaccaa caagagttgc tcttgtcaac
    16021 aataaataac atgaaataaa actcatatga atagataact atttgaaaac gaatttatcg
    16081 gtacatagag ataatcaaat catttaaaag aatatgcagt ttaagctctg aaaaataaga
    16141 attcactttt attagtccaa tcaaacacaa ataccgtttt aagtagcttt tcctctactt
    16201 aaaacggcaa tatgaaagaa actataactt tttattcaat cttttatgtt taactggttt
    16261 atcgccaatt ttttaaaact ttgattattc cttatattat aagaatagac attaagtgaa
    16321 ctaattcaat catactgatt ctttcgtgta ttcaaaatta gatgctgttt aataaaatta
    16381 ttctttttga aaaagaatta taactatatc ccaaaaattg taggttaatt taaagcctat
    16441 ttcatcatcg tgattgagct tctttttcat agacgaattt ctcagatagt ttagttttct
    16501 ttatgagatt tttgtatatt tctgaccttc gatacaactc actatgagta ccttgatcaa
    16561 ctatttttcc ttgatccatc actacaattt tatttacctt ttcaatagac ttcaagcgat
    16621 gcgatataat tagtactgtc ttatcttgta ttaaacgatt taaactttcc tgaatacgtt
    16681 tttcattttc cgcatctaaa ctggcagtaa tttcatctaa aattaaaatt ggcgcatttt
    16741 tcaaaaaagc ccgtgctatg gataggcgtt gtcgctctcc tccagaaagt gaacttccgt
    16801 tttctccgac caatgtatga taaccgtcag gtagtttttc aataaagtct tcgcagttag
    16861 ctaaacgagc tgcttttttc acttcctcat ctgacgcttg actatttcca atacgtatat
    16921 tttccaaaat acttgtatta aacaaagtta cctcttgaaa aacaatagcg attttgctaa
    16981 acaaagaagc tggagataca cgtttaatat catacccatc aattaaaata cagccttcat
    17041 cataatcata cagtctagac actaatttca agatactagt tttcccggaa ccactagcac
    17101 ctactaacgc agtcacttct ccttgtttag ccgtaaaaga gatatgatct aaaattgggg
    17161 tattgttatc atatgagaaa gagacatctc gcaactcaat gtcaaaagat ttcagaggac
    17221 tatctgatcc ctcttggata ctggtttcct tcatagctct aattcgctgt attttaggag
    17281 ctaaataaaa tatttcaagc actgcttctt tcatagaatc gaaggaatcc tttattttta
    17341 ttgcggctag taagtaacca acgacgtaga gtatagtcac ttcacccgtt aacagtaagt
    17401 gaacacctac tagaatgact actgctaaac taacatatga gaaaatagag gataaggcca
    17461 tgactgaaaa agtacttaat tctaccttta aatgaatcct ttcactctct tccatttttt
    17521 tgaaaagtct gtcttgaact tttttagata gattaaagct attaatctct tgctgcaatt
    17581 ctatagtttc ttgaaattct tccgagtttt ctctcaaagt atcgtaatat ttagtattgg
    17641 ctttcgtttg ggatttcttt gataacaaga ttaagacaaa actaaataac gttggcaaaa
    17701 taacagctaa tcccattttg acattaccaa ccaaaagcat cactgaaata aaagggaaaa
    17761 acagagccat accgccggct ttaggtattg catgactcat cgcatgctca ataccttcaa
    17821 cgtcagacat gatagtttga gataaatctg ataaattatg ttttgaaaaa taggataatg
    17881 gtaaatttga caaatcgtct gcaatttgca ttcttaaatg cgcactttct ttataagtac
    17941 tattatataa gttttcatac tccctatcta acaaccaata catgaaaagc aaagtaacga
    18001 acgatactgt aaaataaagc caaggcggct ttacattttc taaaactaat tcgtctatca
    18061 gcatcattat aatgaatgct ggtaccatat taatgcagta tacaaaaaag ctagaaatag
    18121 atgctttaac caaatcttct gcgccctgat tagttaaagc gaatttgttt ttataaaaac
    18181 ttttcattgt caagcctcca atcatttgca ttctcataat tagtgaccaa ttgtttatac
    18241 acttgatgtt tagccattaa ttcattatga tttccacgtt ctactatttt cccttctgac
    18301 aagacaagaa tttcatctac agatttaatg ctggataatc gatgagctat cataataact
    18361 gttttttctt tcatcagatg ttgaaaagcc ttttgtagtt catactcatt atctggatca
    18421 atagatgcac tggcttcatc cataataaca atctttgcat cttttaaaat tgctctggca
    18481 atagctatac gttgtttttc tcctcctgac agataaactc ctttactacc aattaaggta
    18541 tgctctcttt cgggaaattt ttctaaaatc gattcgcaac cggctaatct tagcgcgtca
    18601 aatactttac ttgctggcgc ttgaggattt gctatagaaa cgttatcgta aatactctga
    18661 ttgaatagtt tcgtatcttg aaagacaaaa gcaattgtgt taataattgt gtcttttgaa
    18721 tagtgattta aaggcttacc accaatttta atctgtccct tatccacatt gtagaaacct
    18781 gaaattagtt tagctatcgt actctttccg cttcctgatt ttcctactaa tgcataaatt
    18841 cttttttgtt ctaaaactaa gttgaaattt tctaaaacac actcttcttt gtatgaaaag
    18901 ctgacatttt caaatgcaat gtcacaattt ttaatctgtg tctcgttccc atattttagt
    18961 tggtcttgct tcatttctaa ataaagggag tctagtgttt cgactgcata tcttgcttca
    19021 aacaagtgca tacttacata cattattctc atgaaagaaa caaaaataat tccacttaaa
    19081 aaaaacaaca tcaacaagtc aacagctaat atcttgggag tggtaagaga agttataaaa
    19141 aaggttatag gaactatcaa aatgcaaact atgccaaaaa atagccattg aaaaagaaca
    19201 aaaggtgttt tcccactcaa agaatactta tatgcaaact tagcataatc gttaattgct
    19261 ttattcaagg ctttaaatga tgttacttta gcaccaaata tctttataac ttgaattcct
    19321 cggatatatt ctaccgtttc agagcttaac acatctaacg attcttgata tttttgaata
    19381 aaatttgtat tctctgtcat tttctttaac aagaatacac caattactaa catggcgatt
    19441 agaaccaatc caattttaaa attaatgaaa aagcctaagg caactgataa aacaggtgtt
    19501 actatggctt gagcactatc tggaatcaag tgagcaattg ccatatgtgt tttagccgcg
    19561 ttgtcatcaa ttgtctttcg aatatatccc gaagaattta aatcaaaaaa acgaaaactt
    19621 gcttctgtta aaccgctaat tccctttttt ctcaaattag tctctaagcg aaacccaagg
    19681 atatgagaaa ataagccaga aaaaatataa aataaagctc ctaaagttaa ccaagcaaca
    19741 gtttgaaccg cataactctt agctaaatat tcatctccta caataattag agacttaaga
    19801 aatttgtaaa tactgtaata tccatagact gttaatacga cagaaaaatc agaaaataaa
    19861 gtggctaacc atccgtagta tttcatttta gggacataac taaataattt tttgtatact
    19921 ttcatttttt cctcccccgc attcaatttc ttctcttatt cgtttacaac tgttaatgct
    19981 ttccgtaata gcgtaaatta gagatgtaca aacagataga aggtaaacta cgttctattt
    20041 tttgtatttt tttaagactt ttcttccaat caatacacca atcatagata aacttgctac
    20101 aactaacact gaaatgattc cccatatacc taccgcatag tggatcattg catccattgt
    20161 tgcagcagat tgtcctttat ctatccaatc ttgacgaaaa cgatctgtaa agaaccatat
    20221 aggaatccac tgtccggcag cactgcctaa ttgcattaga gcccaagacg caacttgagg
    20281 aattgctcga tcatatccaa atacagatag aataatatca gctaagatcg ccatactaat
    20341 cgaactgata aaccaaggta agtacgcccc gcccattaac gtaaaaaata acaataaaac
    20401 aattgtgtaa atagtaaaaa ttccttttct agggtagtta tagctaatat aaacaaatat
    20461 gattccagat aataatccaa aaatccctgg ggatatgctg tgaccaaacg ccccaccaat
    20521 actactaacc attattgaaa aaaagtaaat tactagggaa ataactgtag ctaaaccaat
    20581 aaaaatataa tcttttgttt tcatatatat tctcctcaat tctatttcgt tatgtcatta
    20641 aaaatctgtt ctatcaaagt tgaatcttct actctaagtt ttatatcttt ttttattcca
    20701 ccatttttta aataaataat tctattgcat gttttataaa gaaattccgg atcatgagtg
    20761 gctataacta ctgcaccctt ttcttttaag tctttaataa ggtcagcaat cctttccata
    20821 ttaatataat ccaacccact tgtaggttca tcaaatagaa ataaattagt ttttgacaat
    20881 gaagctatag aaaccaataa tctttgtttt tctccaccgg ataaatcaaa cggtaattga
    20941 tctttcattt tataaagttc catttttttt aaaatttttt cttgctgatc tttactaact
    21001 atttcattcc ccagggctaa ctcgctcctc actgattctg tgaaaaattg gtaatccatt
    21061 tcttgcatta ctaaaaacgg cgatgacaaa ttttttttat tttcgattat ctttcctttg
    21121 gtagggcgaa taatcttcat gagtattctt agtaaggttg ttttccccac accgtttttc
    21181 cctaccaaac caataacatc tccaactttg acatcaaaat ttatgtcttt tagaatattt
    21241 tcataagtaa tttcttcaac ttttaataca tctgcactta ccttttcgat atagggaact
    21301 tcaatcgaac tattaaaaat gtcaaatttc cttaatgcgt tattgttttc agtttttaac
    21361 aactgaatag ttgtagtttt tacagttcta tttttaacaa atagaacttg atcaattaat
    21421 tctttcaaat agtaaaaacg atgttcagct ataacaatag taaatccttt attttttaaa
    21481 tcacaaagta agtcagcaag tttcttagtc gctttgaagt ccaaatttga agacggttca
    21541 tccaatataa ttaatttaga gtttagcgat aaactacatc caatagaaat tttctgccgt
    21601 tcaccacttg atagcgaaaa aatgttttta tctaatatat ttgaaagatc taataattca
    21661 gctaattcat tgattctttt atccatatgc tcttttgtaa atccaaagtt ttccatcgaa
    21721 aatactaact cactcgttgt atttgttgta aagaattgtc ctctaggatc ttgacttacg
    21781 tagccaatat tttttgatat actttcttgt gttaaggatt gtagcgagtt attttcaaat
    21841 aaaatttccc caaccaattt tccgtcataa agtcttggaa taagtccatt cattaacttt
    21901 aatagtgtgg atttcccact cccagaagaa ccagtaatca atgtaagact accttttttt
    21961 attgaaaaat taaggtcaac aagcgcttgt tccttaacat ccttatatga aaaagaaaca
    22021 ttgttaaatt caaacaattc tttcacctca aatcaaaata cttaagaaaa aaatagtaac
    22081 ggaaaacagg atgatatagt ctaataagct catgtttgtt ttatagtaag aacttctttt
    22141 cacaggagat tctatcccct ttgttattgc attagcggtc atttcttcag caatcatagt
    22201 tgcacgtata agaacgggaa ctaacagaaa ttccaaatat tgcagaggct gaaaaaaaga
    22261 caagcgaatg tttctcattt ttaaagattc tttaatcatt cttatttcag aacgataagt
    22321 cggaaagaat ctgatcacta ctgtaatact taacattatt tttttcggta aatgtatttt
    22381 ttctaaagag gataataatt cattgctagt atagacacta accaacaacc atgagatcat
    22441 tacgaccggc aacattcgaa atacaatata taaggatgtc ccaaaaaata tagtaaaaaa
    22501 ctctatcttg atagcatcaa taattttcat tactaaaaac agaactgaat aaatcaagat
    22561 gaaataaata catgtcttta ttttacgaaa catcaatact aaaactgtag caataatgaa
    22621 acaccccact tgaaatatat ttccctttcc taaaaaaata atgaccggaa aaaaaatatt
    22681 taaagtaatc aaggttaacg gattgatttt tgacactctt tcacctccaa aaaataagat
    22741 cgcactgtta tcttaagctg ataaaaatgc accgttattc agataacagt gcgatcttat
    22801 caaaaagcat aactgagaac aattctcaat gcaagctttt ttttaattaa ctcagtaatt
    22861 caatccaccc aggaacagaa aattgataca atcttctggt taatagcata gtcttttctt
    22921 ttgaatagct atgcttcaat atatcataga atgtagcgta gaatgagtaa atgtagaagt
    22981 ggatttcttc ttcattaaag actaaatttt gattgatcat tccgatagtc tttaacttat
    23041 ctagacaaca gactgtcttt tttgtcacaa atgatgtaat tttttcaaca atatcttgat
    23101 atttggttcc agctgattgg aataaaacca aatcgaatat acgtttattc tcaaaaatat
    23161 aattaataaa tggatctaat tcattgaagt tctctctcca acttttctct atatctatat
    23221 tttctaagtt taagaggtat ttggtaaact cttcattata catattaata agcgcattaa
    23281 tatgcggctg aataatttct tcaaataacg cttccttaga agtaaaatgt ttataaaaag
    23341 cacccgtagt tacgcctgcg gtcaagcaca gttgccttat cttagtttgc tgaaatccta
    23401 ctttttcaaa atggcttagt ccactttcta ttaatttttg gtgagttgta atataatctc
    23461 tggtttctat gggtacttcc tcctaataag atgaattaac tatattatct tacacaggac
    23521 ttgaagtttc aatcgttaac gtctattact gaactcattc cttagagcta aactaatgag
    23581 aaagagcaaa ataactgata caaaaagcaa tcctacaaga attaatagac tcatctaaat
    23641 cattcacctt ttctaaaata atccgagaaa gatttaaaaa aattatatcc agctattagg
    23701 ataagtccta tcataatcac tccaatagcc attttcttat cctccctaaa aataaagcct
    23761 tttacttaaa accttttttt gtaatcgtca ataaattttt tccctttatc agttaattga
    23821 aatcctatat ctaaatagtc ctcatatcta agtttagtca gcatctcact tacagatgct
    23881 ggactaacac ttagaacttt tgctaaatca ttatttttta atttcttttt tctttttgat
    23941 aattcctgaa ttgctagtaa ataaattagt atagtagttg ttttaatttg taccatacct
    24001 accctccaaa ttatttcgaa aggccttcag caattttatc caggttccat ttcatcatcg
    24061 catagtaact atcaccatct tgtccttttt ctgcaattga atcagtaaaa atcgttgaat
    24121 agataggaat attggtatct tttgatactg ttttcattgg tctatcgtcc acactgcttt
    24181 ctacgaataa ggagggaact tttgttgtgc gtaatttttc aactaagtgt tttatttgat
    24241 ctggtgttcc ttcttcttca gtgttgattt cccaaatgta agcagaaggc acattatacg
    24301 ctttcgagaa atatttaaag catccttcac ttgtaacaat cattttttta tcattcggaa
    24361 ttgaagcaaa tttagattta gcttctttgt ctagagaatc caatttttca atatacttat
    24421 ctagattttc tttatagaat tttttattat caggatcttt ttccgctaac tgtttttcaa
    24481 tatttttagc gtaaataata ccgttttcta aatttaacca agcatgggga tcttccttcc
    24541 ctttctcact ctgaccctct aagtaaataa catctatgcc atcacttgct gcaaaatagt
    24601 ctttgttttc ctctttgttc gcatttttta ctaattttgt aaaccaagca tttcctccag
    24661 tttccaagtt aacaccgtta taaaaaatca aatctgcttt tgaagttttt tgaacatctt
    24721 caggcaaagg ttcatattcg tggggatctt tcccaatagg tacgatactg tgtaaatcaa
    24781 ttttatcttt tgctatattt tcagtaatat ctgctaaaat cgaattagta actactacct
    24841 ttaatttttc gttcgaagcc actgtatctt tgtctttact atttgttgaa catgccccga
    24901 atataaaaag agcaatcaaa atccccagac ttcccagtac tgctttccat tttctcatca
    24961 taactttctc tccttctttc ttaaaaattt ttgttttggt gagattagaa aactaattac
    25021 aaataagaat gccgctgtta aaacaatact tgatcctgct gctatgttaa aactataacc
    25081 aatgaacaaa cctagcaatg atgagcacgc tccgactgtc gccgaaataa atatcatagt
    25141 ttttaaactg tttgcatata aatatgctgt agcagctggt gtaattaaca ttgcaacaat
    25201 taatatagtt cccacacttt gcatagctgt tactgctact aaagttaata gaatcattaa
    25261 tagataatga taaaaactga cattcatccc cattgctttt gccattaatg gatcaaaaga
    25321 agtgattaat aattctttaa aaaatagaac aactgtaacc aacactaaaa cagaaacgcc
    25381 aattgtaatc cacttatcaa tatcttgtac agctaaaata tttccaaata agatatgaaa
    25441 taaatccgtt gagctatttg caactcctat aaggataact cctaatgcta aaaaagaact
    25501 gaaagtaata ccaattgctg tatctccttt tattacacta ttgcttttta taaaagtaat
    25561 aatgatagaa gctaatagac caaatacaat cgcaccaata aaaaaattaa tacctaaaat
    25621 ataagaaatt gctactcctg gcaaaacagc atgagaaata gcatcaccca taagagacat
    25681 tcctcttaaa ataataaaac aacctactgt tccagaaaca atccctataa ctacagatgt
    25741 aattagagca ttctgtaaaa agtgaaagtc atacagacca ttaataaaat tttgaagcat
    25801 attattcccc ttgtatatta gagttagggt tttaaccttc cggttttgat tggataaccc
    25861 tatgaaccat cgttatttta atttggtatt aactcatttc ttttgagata atatatttat
    25921 tggattgaga ggctaagccg ttcccccctc tccaataaat atagtatctc cataggcttt
    25981 ttttaaattc tcttcattaa atacagattc tacacttccg tgagcaatta gatttcgatt
    26041 caaaagaata atattatcaa aatacttctt taccttgctt aaatcatgat gcacaattag
    26101 cactgttttt ccctgatgtt tcaattcttt taacgtatcc ataattattc gttcactaac
    26161 taagtctatc cctacaaatg gttcatctaa aaatatgaaa tccgcatttt gagcaagaca
    26221 tcttgctaaa agtacacgtt gaaattgtcc tccagataat tctcctattt gatgattaga
    26281 atattttccc atatcgacct tttccaaagc ctttgaaact ctttgccatt ctgcattttt
    26341 aattctttga aaaactttca ttccggcata tgttcccata gatacacatt cttttacttt
    26401 tattggaaaa gtaaaatcaa tatcagcttt ttgctctaca tatgcaatct tcaccagttt
    26461 tttattgata tcttcattat taatggagac ctctccctga tgagggataa tatttaacat
    26521 tgctttaagc aatgtagatt ttccagcacc atttggacca ataatacctg ttaaagcacc
    26581 ttcttgtatt tttaaagaaa tctcgttcaa tgctaaaaaa tcgttataac aaacattaag
    26641 ctttttcact tctaacataa ctttctcctt ctaaatgata atgattatca cgatcatatg
    26701 gtatacaaaa attatatttt agtcaaccct aaattttata atttagattt ttttctgttg
    26761 ttgaagatta ggatgtcaaa attatttgaa actactcgta tagtaaatag taagtaattt
    26821 tcaaaacacg aagaaaaaca aaaagaaaaa aggaaacgcc gaagcatttc ctttcagtga
    26881 tttaatgaga acaacacgat ttgacttaga gtctcaaaaa gtcgaatagg tacactcatt
    26941 taagtgtctc cattcgactt tttggggatg agctggctat tgaggtccgc ttaccctatt
    27001 gaataaatac aagattgggt atttctaata agtccgccct tcatattggg gtgatcgggg
    27061 cgaacatgcc atcttttcat ataccacctc ctcgacactc aataatcaaa gattctcgtt
    27121 aatcttcttc gatgcttgca atgatgtttt caatattcat ataacgaaaa tcttcttgtt
    27181 tgatataaac gatctgagcg gtacattttt cctttttgat gatttctttt actttttcct
    27241 cagaacgtgc gacctgcggc gttaaaagta aaacgtcata gtctttataa ttcagttttt
    27301 cttcaacgtt tcggatcgtt gcataatcta tctcatacga tagatttttg gctctgatcg
    27361 tttcaagcat ttttgatacg agcagcgacg cactgattcc ggtctcgcaa ataatcaata
    27421 gatccttatg cataataccc tcctgttttt agcctgcaaa gccaattggt gaaaatgcca
    27481 cataagttaa aataacaatg actaccaatg ctatagcagt caccttggtg tatttccaag
    27541 gctcgatatc gacctttgta tcgaatgagt tcaacacaaa ttctccatca ggtttcaatt
    27601 tggaaaccac catcaaaatg ataatgtcca gaacgaataa tgccgtcaaa acataaagga
    27661 aatggatatt ttggaaaagc atttttgata gtgcatacaa gacgatatgc acggcaatcg
    27721 tcgtttttgc cccaaaagca gttgcttttt ttgaataaaa ggcaaagaga atgatcacga
    27781 gcagcggcat gttgtatagt ccattgaatt cttgaacgaa ctgatacaat ccagccggtg
    27841 caaaagaaat gaatggcgct acgataatgg agataatccc cacaacgacc gttactgttt
    27901 taccagcacg agcgatttgc ttatcatttg ctttcttatt gataagcggt ttataaaaat
    27961 ccagtgaaaa caaggtcgat gtcgcgttca aagctcccgc aaatgatgat aagatcgcgc
    28021 caaagataac agcggcgaaa ataccaaaga tcattttagg caatacttca ctgactaaaa
    28081 aaggatacgc gttatctgga tttgacatta aactatcgcc aaaaatattg cgagcgacga
    28141 tccctggaaa gacaaggaat aacgcaccta agattttgaa gacgccgact aggaaagcgc
    28201 ccttttgtgc ctcagctaaa ttcttgccgg acaatgcttt ttggacgatc atttgattgg
    28261 tacaccagaa atacagattg ttaaacagca tccctgtaaa tagtgtcggc catggaacaa
    28321 cagccgagtc gatcgatccc acagagttaa gcagccatgg cgtgtttacc acaacgtgtt
    28381 cgatcccgcc aacaaagctg ccgtcaccaa gcttcattaa gcctaaaatt gggaccagca
    28441 gaccacaagc cagcagaccg actccataaa tggagtcact attggcactt aacgacaagc
    28501 cgccgatcag cagatagagg atgccgacaa taccaattgc catcgctaca attatgatcg
    28561 cgacgatcgg ctggacgccc agcagctcat caatatggaa gatcttattg aacaccagcg
    28621 atccagaata aagaaccacg ggtaagaaag aagtcatata ggtcacaata aataagatcg
    28681 aaataattcg tttggtaacc gtatcataac gaatctcgat gaaatctgag attgtattga
    28741 tgccgtattt aaaatatttt ggcaagaata tcacagccaa agctacgatc gcaatcgtag
    28801 cagttacttc ccaggccatt acttccatcc ctgcatgata actttgacca ttttgtccga
    28861 ctatttgttc ggtggacagg ttcgtcatga tgatcgtgcc ggcgattggc aaagcagtta
    28921 agctccgccc tcccatgaag aacccttctg atccagaagt atcgacactt ctggatctag
    28981 aataggcaaa taaccataca cagatgacaa tcactaggaa actgattata gaaaaaagat
    29041 tcatcgtcta gctccttttc aatagattaa agaccggtga cctctcgaat gtagcttctg
    29101 gctttgactg catattcaaa tggattggct ttagccgggt cctgttctgc ttcaactacg
    29161 atccagcctt catagtcgct ggcatggatt gctgtccaga ttggagtgaa atcaatcatc
    29221 ccatcaccag gaaccgtgaa gacgcctttc ttcacgccgt ttaagaagct gtctttttcc
    29281 ttttctactt cttcagccgt ttcttgacga atatctttga aatggatgtg tttgatacga
    29341 tcttgatgac ggttgtaaac cgcgattgga ttttcaccag aaaagaccaa atgtcccgta
    29401 tcgaacaata atttaacttt gtctggatca gtcatttcca ttaaacgatc gatttcttcc
    29461 gtcgtttgaa cgccggtacc catgtgatga tggtaaacga tctccatatc cttttcgtgg
    29521 gccaaatccc ctaatttttc taatccttcc gccagttttt tccactcttc atcagtgaaa
    29581 actggtttat catcaaagac tggcgctgtc ataatccctt ggatactatg accctgctca
    29641 gctactacga tgactttagc gcccatcgca tgtaagaaat cccgatgtgc tttgaaggct
    29701 tcggcagttt cttcaaaagg tttagttgtc agaaacgcac tgaaccatgc actggcaacc
    29761 tttaagccgc gaatattcaa atattgttcc aacacctctg gatcttttgg atatttgttg
    29821 ccaatctctg ttccggtgaa cccagcaagg gccatttcac tgatacattg ttcaaaggta
    29881 ttttcactac caagctcggg catatcatca ttggtccacg cgattggtgc gatggctaat
    29941 tgaatttgtt tggtcatatt ctcacactcc tgcttatttt tttagttgta ctaaactctt
    30001 cgtatcgaat gattcttgac aagccaacgc gatcttagtt gattgcaatc catcttctgc
    30061 attaaccgct ggttgacgtt tttcttgaat acatgagaca aattcttggg cttcacgaat
    30121 gaaggcttct ctgaatcgtt ctgggaagtt ttgtgaacat ggacggatga tcccttgatc
    30181 gttcatgatc gtcacaagat ttttctcagg cgcttgcgct acccgcagca ttcctttggt
    30241 tcccatgatc tctgtttcga catgatagcc atgggctgcg tttctgccgg caactagtaa
    30301 agctattgtt ttatcgctca ggctcatcat tgcggctcca gtttcaagct caccagcctg
    30361 atccaattct ggatacgccg catttttccc aatcgcccac acttgatcga cttcttggcc
    30421 ggtaaaccag cgaaccaaat caatatcatg gatcgccata tctaagaaca agccgccgct
    30481 gtcgttattc atggcaaatt tgacaaagct ttccaagcct tcgctcggat cgatcccata
    30541 acaacgaatc agtgtgattt cgccgatttc gccatcttct accattttct tcgcatactg
    30601 atacgactca tcatagcggc gcatgaagcc taacatgaag acctgttcag gatgctcttc
    30661 gatgactttt tgggtctttt taatatcttc aacttcaagg cctaatggtt tttcagtaaa
    30721 gacatgcttg ccattttcca tcgccaagcg gacttggtca cagtgaaagc ctgatggtga
    30781 aacaataaag actgcatcga tcacggaact tttgaccatt tcttcatagc tggaaaaagt
    30841 atgcttgacg cctaatttct tctgtgcgaa tgctaattct gtttcaacta aactgcacgc
    30901 agccgtaagc tcacaacaac tgacacctgt tgctaaattt tgtgcatgta cttttcctaa
    30961 tcttcctaaa ccgacgatgc ctactctaat gttgttcatg aaatacctcc gttttctgag
    31021 aattactcat tgtatagtgc tggtcgttca tccatttgaa tcattacttt tgtttttgtt
    31081 tcacgagact catgacaagc catcatggtg atcgctgcta catacccatc ccaagcggta
    31141 ggaccgacaa ccgcatcatt tttgatcgaa tcgatccaca gcttgaattc ataatcatag
    31201 gcatccaaaa agcgggtctg ccaatctggt gaaacaggtg tgtaattttt ttcttccgat
    31261 ttaattcgtg tataggctgg gtccgtcatt cctacttctg ccgtttcgaa aaccacatca
    31321 catttaatat cgtagccaaa gcggcaattc acaaagattt ccaaatcaat cgttacaccg
    31381 gattttgttt gaaagatcag cagctgcgga tcatgcaaat cggcatggga gttgctggtt
    31441 tttttcggca agatcatttg aacagattca taatcttcat ttagcaacca gcgaagcaca
    31501 tcaatctcat gaatcgcggt gttgctgatc gccatcggtg ttgtgtagtt ttcatctgcg
    31561 ctaggatttc tatgggcaca atgcatcatt aatgcttctc cgtattgctt cgattcgatt
    31621 gcttctttca gttcaatgta gccgcggtca tagcggcgca tgaagccaac ctgaaccaat
    31681 ttcttcccat aagcaacttc cgcatcaacg atccggcggc agcctgctgc atccatcgct
    31741 aatggctttt cgcagaaaac atatttccca tgcttgattg cttctaacac atactgctca
    31801 tgggtcgggt cccaagaagt cacaacaacg acatccacat cttcagaagc gatcaatgct
    31861 tctccggttt caaagaattt agcatcgaca cgtttggcaa cctctttagc agcttttaca
    31921 ttgatatctg agactgctgt cacataagcc ccttgtgttt tctgattgat cctgtcgata
    31981 tgctcgatgc cgattgcacc tgttccgata acgcctactt ttactctcaa ttacttatcc
    32041 ccctgttctg ttgtttaagc acacatagta tgcgcttaca aaattattcc tgtgtagctt
    32101 ttattcttaa aaggtagagc cctctctttg ctccgccttt tactacccat aagcttgtac
    32161 gtataattcc ttaatttgac tatgactagg caccttttta ttattttgcg gacttccgct
    32221 ggtcaacgca tccgcggcca ttttgtctaa ggctgccata aacgcttgct gatcaatacc
    32281 ataatctcga atcgttggga tcgacagctg ctcacagagc tcttggattt ttttaatcag
    32341 ataatccgca gcctcttcca gcgataaatc ttcggctgcc ggataaataa atctggcgat
    32401 cgtcgctaac tcagtctgaa tagcatcctt tgagaattca aaaaagaccg gcaataacat
    32461 cgcatttgat atcccatgag gaatgtgaaa aagtgccccc accggtcgac tcattccatg
    32521 aatcaatgtg actgacgcat tcgaaaaggc aatccccgcc tccgttgaag ctaagctcat
    32581 ttgttctctg gcttcagtgt cgtcgctatt ttcatatgcc tgagaaagcg tgttcaaaat
    32641 tttcttcatc gcttccagtg aaaatagttg cgttacttca ttggctttga ctgaaacata
    32701 agattccaaa gcgtgacata gcgcatcgac tcccgttgcc gcggttactt ttggtggtac
    32761 agttttcgta aaatcagagt caacgattga gatctgtggc atgaaaacga gatccttcat
    32821 catcattttg actgctgttt ttgtattggt aataactgcc acatcggtta cttccgaacc
    32881 agttccagca gttgttgaca ctgcaatcag cggaatgccc gcttgcagct gatcaaaatt
    32941 tcttgcatga atcgcttcga gacttaattg attagcagcc aaaacggcta ccaccttggc
    33001 tgtatccaga cagctgccgc caccaaaagc aatgatatga tcacattgat gcttctgaaa
    33061 aagcttcagc gcatcataaa cattttcttg cgtcggttcg gcttgaatgt ctgtatactc
    33121 cgctaattga tcatctgttt ttcccaacag ctccttgatc ttttgaagat gcccggtctg
    33181 ttccataacc gtatcactaa tgattaacgg cttgttgcct agttgttctg attcttccat
    33241 aagaaattgg attgttccgc cgccaattct taaattggca ggcattttca gttgaatatt
    33301 cacagaaaaa acctctctct ggcttatagc ctataacaga atcctcgaag ctctttaaca
    33361 gagcttcgaa gcaaatcttt aaatctcact ttgcgcataa cgtgctgtaa caactttccg
    33421 atgggtataa aactcaacac tgtctttgcc attggcatgc aaatcaccaa agaaagagtg
    33481 cttccagcct gaaaaggcaa accaagccat cggtgcaggc accccaagat tgacccccag
    33541 catcccagca tcaacatttt ctctgaagta gcgaatcgct gatgcgttgt tggtatacag
    33601 acacgaacca ttcgcaaatt cagattcatt cgtcagctca acggctgcca tcaaatcttt
    33661 tacccgcacg attgatgcga ccggggcaaa aatctcatcc tgccagatct tcatatccat
    33721 cgtgacatta tcaaaaatcg ttggtccaac aaaatagcct ttttctggaa tgttttcgcg
    33781 accatctagt accagtttcg ctccttcatc gacccctttt tggatatagt caaaggtccg
    33841 ctgctgtgca tcttttcgaa tcactggtcc taaaaagacc ccttcgtcca agccattgcc
    33901 gatcttgatc gcttttgccg cagccttaaa tttttcaaca aactgatccg cgatttcctc
    33961 ttccaaaaca atgacggagg ctgccatgca gcgttcacca gcagaaccaa aagctccgcc
    34021 aataaggtcc ttgactgccc gatcaatatt ggcatctttc agcacaacaa catgattttt
    34081 cgctccagtc aacgcttgta cccgttttag attttttgtt ccttcacggt aaacgtattc
    34141 accgacattt tttgatccta caaagctgat gccttttacc agtggatctt gcagcaatgt
    34201 gttgacaaca tcgtgggcac catagacaac attaaaaaca ccgctaggaa agcctgcttt
    34261 ttcaaccagc tcaacaattt tctccatcaa caatggtgtt ttttctgaag gcttcagcac
    34321 caccgtattt cctgccgcca gagccatcgg gaagatccag aagggcacca tcattggaaa
    34381 attaaacggt gtgatccctc cgattactcc gattgggtaa cgataattcg tgatctcaat
    34441 atcagtcgcc gctgttgata aagaatctcc catcattaaa ttggtgattc ccgctgcgtg
    34501 ctccacattt tcgattcctc gttgaacttc tcccagtgac tcggacaatg atttcccatt
    34561 ttccagcgtg atcaaacgcg ccaattcact tttatgatct gttaaaagct gatgcagctt
    34621 gaacagataa cgtccgcgaa caggaacagg aacttttttc caagtttgaa acgcagcatc
    34681 ggcagcttta actgcttcgg ctgtctctgc tttgctagac aacggtacat tcgccagcgc
    34741 ttcttctgta gccggattca ttacttcttc aaactctgtt gagcgactag cgacccaacg
    34801 accatcaata taatttctta aaaatcttgt cattta
//
LOCUS       DADQDV010000025        34770 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.025, whole genome shotgun sequence.
ACCESSION   DADQDV010000025 DADQDV010000000
VERSION     DADQDV010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 34770)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34770)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34770
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.025"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(226..1113)
                     /locus_tag="J8S10_001295"
     CDS             complement(226..1113)
                     /locus_tag="J8S10_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAZ9629885.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(1110..1979)
                     /locus_tag="J8S10_001296"
     CDS             complement(1110..1979)
                     /locus_tag="J8S10_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAZ9629886.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(2116..3402)
                     /locus_tag="J8S10_001297"
     CDS             complement(2116..3402)
                     /locus_tag="J8S10_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HAZ9629887.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            3675..4253
                     /locus_tag="J8S10_001298"
     CDS             3675..4253
                     /locus_tag="J8S10_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAZ9629888.1"
                     /translation="MPIRVILIDDEQTNLDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            4253..5182
                     /locus_tag="J8S10_001299"
     CDS             4253..5182
                     /locus_tag="J8S10_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAZ9629889.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            5179..6915
                     /locus_tag="J8S10_001300"
     CDS             5179..6915
                     /locus_tag="J8S10_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAZ9629890.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(6978..7814)
                     /gene="pheA"
                     /locus_tag="J8S10_001301"
     CDS             complement(6978..7814)
                     /gene="pheA"
                     /locus_tag="J8S10_001301"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HAZ9629891.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(7811..8320)
                     /locus_tag="J8S10_001302"
     CDS             complement(7811..8320)
                     /locus_tag="J8S10_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HAZ9629892.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(8313..9608)
                     /gene="aroA"
                     /locus_tag="J8S10_001303"
     CDS             complement(8313..9608)
                     /gene="aroA"
                     /locus_tag="J8S10_001303"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HAZ9629893.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(9621..10712)
                     /locus_tag="J8S10_001304"
     CDS             complement(9621..10712)
                     /locus_tag="J8S10_001304"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HAZ9629894.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(10729..11895)
                     /gene="aroC"
                     /locus_tag="J8S10_001305"
     CDS             complement(10729..11895)
                     /gene="aroC"
                     /locus_tag="J8S10_001305"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HAZ9629895.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(11897..12961)
                     /gene="aroB"
                     /locus_tag="J8S10_001306"
     CDS             complement(11897..12961)
                     /gene="aroB"
                     /locus_tag="J8S10_001306"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HAZ9629896.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(12994..14016)
                     /gene="aroF"
                     /locus_tag="J8S10_001307"
     CDS             complement(12994..14016)
                     /gene="aroF"
                     /locus_tag="J8S10_001307"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HAZ9629897.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(14675..15649)
                     /locus_tag="J8S10_001308"
     CDS             complement(14675..15649)
                     /locus_tag="J8S10_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HAZ9629898.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(15630..17513)
                     /locus_tag="J8S10_001309"
     CDS             complement(15630..17513)
                     /locus_tag="J8S10_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HAZ9629899.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(17531..19756)
                     /locus_tag="J8S10_001310"
     CDS             complement(17531..19756)
                     /locus_tag="J8S10_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HAZ9629900.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            19871..20905
                     /locus_tag="J8S10_001311"
     CDS             19871..20905
                     /locus_tag="J8S10_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAZ9629901.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(20972..21985)
                     /locus_tag="J8S10_001312"
     CDS             complement(20972..21985)
                     /locus_tag="J8S10_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAZ9629902.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(22063..22251)
                     /locus_tag="J8S10_001313"
     CDS             complement(22063..22251)
                     /locus_tag="J8S10_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HAZ9629903.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
     gene            complement(22691..22819)
                     /locus_tag="J8S10_001314"
     CDS             complement(22691..22819)
                     /locus_tag="J8S10_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HAZ9629904.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(22822..24195)
                     /gene="rlmD"
                     /locus_tag="J8S10_001315"
     CDS             complement(22822..24195)
                     /gene="rlmD"
                     /locus_tag="J8S10_001315"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HAZ9629905.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(24306..25361)
                     /locus_tag="J8S10_001316"
     CDS             complement(24306..25361)
                     /locus_tag="J8S10_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HAZ9629906.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(25371..26801)
                     /gene="gatB"
                     /locus_tag="J8S10_001317"
     CDS             complement(25371..26801)
                     /gene="gatB"
                     /locus_tag="J8S10_001317"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HAZ9629907.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(26798..28270)
                     /gene="gatA"
                     /locus_tag="J8S10_001318"
     CDS             complement(26798..28270)
                     /gene="gatA"
                     /locus_tag="J8S10_001318"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HAZ9629908.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKTTFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(28270..28575)
                     /gene="gatC"
                     /locus_tag="J8S10_001319"
     CDS             complement(28270..28575)
                     /gene="gatC"
                     /locus_tag="J8S10_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HAZ9629909.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(28681..30717)
                     /gene="ligA"
                     /locus_tag="J8S10_001320"
     CDS             complement(28681..30717)
                     /gene="ligA"
                     /locus_tag="J8S10_001320"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HAZ9629910.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTIKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(30734..32968)
                     /gene="pcrA"
                     /locus_tag="J8S10_001321"
     CDS             complement(30734..32968)
                     /gene="pcrA"
                     /locus_tag="J8S10_001321"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HAZ9629911.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLVNPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            33123..34682
                     /locus_tag="J8S10_001322"
     CDS             33123..34682
                     /locus_tag="J8S10_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HAZ9629912.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQNVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
BASE COUNT         9519 a         7494 c         6335 g        11422 t
ORIGIN      
        1 acaatcagga cagtcatcgg caatatagca gcaatcactt ctttaaaatt ttttagcatg
       61 tatcctcctc ctttactctt taagtttacc ttaaaatgaa agagttttcg agcacaaact
      121 taaaacgtta tcatttaatt tttctcaaca taaaataaca cacgtcccaa aagtatcttt
      181 ttacttggaa aaatgacttt gaaggaacgc gcttattgtg tttttttatt ttacagagcc
      241 gatcattcct tgaacgaatt gcttttgcaa aacaaaaaat acgatggcag ttggtaaagt
      301 agcgatgact aatccagcca tgatcattcc atagtctggt gtataggaag cacccatagc
      361 agataaaaca agcggaaccg tccgtttatc aggagattgc aaagctacta agggccataa
      421 ataattgttc cagctactca tgaatgtgat gattgcagcc gcggcatagg tatttttagc
      481 cgtcggcata tacactctaa aaaaaatact tagttctttt agaccgtcta atcgagcggc
      541 ttctactaga tcttttggaa aagatttaac attttgtcga aagaagaaga tcaaaaaagc
      601 agtgctaaca gatggcagga tgacaaccaa gaaactgttg attcccaaaa ccgttccgtt
      661 caattgtgaa aacattcgat ataaagggat catcaatgcc gcaaaaggaa ccatcatcga
      721 tagcagtaga atattgaaaa ttaggtcttt tcgtttactt tgataaatct caaatccata
      781 tcctgccatt gacgaaatca gcaatgcaaa cacagtggtc accaaagcga tcatcgctga
      841 attccaaagg gaacgagtaa aattcagctc attggaaaac aaattttgaa aattgatgat
      901 caagttactg ccaatcttta tttttcccga tgtgatatcc acgggtgtat tcgtcattcc
      961 caaaaccatc cagacaaaag ggaaaatgga aataaatgat aggatgctta atgctgtata
     1021 ctttaatact gacccaattg tcgaacgaag ttctaatgct tgttttttga cgttggggcg
     1081 ttcgattgtt tctttttcta ccatattttt catcgacttt ctcctcctac tttcgtttgg
     1141 attatcgaca atatcacaat aaaggaaaca ataacaaagg aaactgctgc cgcatatcca
     1201 aaattaggcg tgaatttata actcaaatta tagatgtatt gagatagggt ggtcgttgca
     1261 tttgctggtc ccccgccagt aatattttgt acttcatcaa aaagctgcaa tgtcccgatc
     1321 gtcgaagtaa tggaagtaaa caaaatgatt ggttttaaat ttgggatcgt cactttgata
     1381 aactgctgcc atttagaagc accgtcaata gatgctgctt cataaatctc cgaatcaata
     1441 ttttgcatgc ctgaaaggaa aaaaatcata ttgtatccag tccaacgcca agtgatcgaa
     1501 agaatgatca gaactctcgc ccaaattgga tgagtcaacc agccaatcgg tgtgtcaatc
     1561 ataccaatgc ccaacaacaa gttgtttaca aggccagatt gagaaaatag acttttcatg
     1621 atcagagaat aactgaccat cgaagtgata catggaagaa agatagcggt tcgaaacaac
     1681 cctttatatt tcaacttttt atcatttaaa aggttggaaa taaaaagtgc tagaaacaac
     1741 atgatcggta cttgtacaag taaatacagg aatgtattaa aaaaagcttt tttaaaagtt
     1801 gcatctgtca acatccgctg ataattacct aacccgttaa atgtcatatt gacaggggga
     1861 ccactttgaa aagacgtgat caaagccaaa accatcggaa taaaaaccat gattgatatc
     1921 aaaatgactg gcaagattaa aaaagcatgc ccgtttttga ataaatcttt ctgcttcatt
     1981 cttttccctc caattctatc attgattatc tacatgaaaa gacaagaaag acaatatctg
     2041 taaggcagac gtgatctttt ttgtcttttc gtttgtctga tgaaaaagcg aagaaattca
     2101 cttttttacc accgatcaat tagccaattg tgcttctact tgtttttgtg tatctgctag
     2161 taccttgtct gtctcttctc cattgatgat tcgatgaaga gcttcagcta cgactgcttc
     2221 aattgcatag gtctcatgtc cgtaattcac ttctggtatt tcagatgtcc atgttgaaaa
     2281 atcgtcaaag atcttttgac cactgtaaaa ttcagaagct tcttgataag cttcttgttc
     2341 attcgcgcta agcatcgtag atactagtcc gatttctttc gcaagagtgc ccatcagttc
     2401 ttcattcgaa gcaaacgttg cttctaggaa atctttcgct gaatcttctc cagctactcc
     2461 tttgatcaca taccagccag cgccgccaag gttagaagct tgcgcttttt gcagattttc
     2521 tggaagtgca ggtattggtg caatcttcca ttttccagat tggttttctg ctccttggat
     2581 cgttgaagaa taccaagcgc cagttgggct agaagctact gctcctgatt gtatcgcagt
     2641 tactccagca ttccagtcag aggtttgttc gactagatct tctttcaaaa gagtggcaaa
     2701 caattcaaga ccatacttta aagatgcatt gtcttggatc gtgactgtct ccccatcttc
     2761 agatgtatac cattctcctg cctgttgcat aatcatcctt actcgaccaa ggtcagaagg
     2821 attgacttca gcgattttct ttcccgtctt ttctttgaca tctcgcgcta cttgaatata
     2881 ctcgtcccac ttcagattct ccatatcctc ttctgtataa cctgcttctg ccatcagatc
     2941 cgtacgatag aagtttgctg ttacgcccga atcgaaagga acaccgtata ttttatctcc
     3001 tactttgttt accgcaaatt tatacggtgc aaaatgatct tcctttacaa tagcagacaa
     3061 attagcgaat gcatctggat aagaagtcaa atagccttgt atcctataat cttcaatcaa
     3121 gacgatattg ggcaatcctt ctgtattccc gctcgctaaa gcggtgttca gtttctgaac
     3181 gatatcatcc tgagacatcg taacaacttc tatctctgtt tcttcgttct cataaacttt
     3241 ttttgcttca ttcactgctt tgatattgaa tgtctcatcc cacgcccaga cagtgacttt
     3301 ttcttctttg tctgctgtac tactagcact tccgcatcct gttaagaaac ctgatgctgc
     3361 cgctaaacaa acgactccag caattaactt tctgatgttc atttttatcc gctccttttc
     3421 catccattag ttgtttacgt ttgctacatt catcatacca aaatttgaaa acggtttctt
     3481 tattattcag atacttcaaa aatttctcct aaaataataa aaaaatacaa atcaactatg
     3541 acaaaaggaa taatcttagc atctagacca aagatcgaaa tggtgaggtt tctttaaaat
     3601 aaaaatatcc ttgcattttc tcctagaaat aagtattttt aaattacaag actattctta
     3661 aggcgggtaa aaaaatgcca atacgcgtaa ttcttatcga tgatgaacag acgaatttag
     3721 atggaatgaa acagttgatc aattggtctg agcacgggtt tcaattaata gggacttttt
     3781 ccagtccgct gaaagcgctt gatttttctt tggtacatgc aatcgatatc gtggtcacag
     3841 atgtaatgat gcctgaatta aatggaatcg aattatcgcg gctattaaaa cagcaacaac
     3901 ctgaaacaca gatccttatc ctctctagct atgatgaatt tgatatggtt aaagattctt
     3961 ttaaagaagg cgtcgctgat tatcttttaa agcctcgatt gagtcctgat ttttttctaa
     4021 attccttaac tgccgtttca caaaaaatca aaaaaaagcc caacaaaagc ccaatcacca
     4081 atcgttatga gcagatctgc gagaatcttt cacagcagat tgctggacaa actcgtccat
     4141 tgcttgaccc tcttcttttt gaacacacct tgtttttctg ttatataccg aaaaacggcc
     4201 attcagttca aaacaaggct ctaaacaaaa acagtcgatc acccattcat tgatggatag
     4261 cgacgattcg tttactattt atcctgtttc taccttttcg gaagaatccg gctatgtaat
     4321 caatactgat tccaaagata cacttaggaa gtttgttcaa aagtttcgtc aagaagtttt
     4381 tccaggtgat ttttttgttg tttctgattc ttttgcaatc caagatatca atgaaatatt
     4441 ccaagagatc agaaattgca ccaaaggaca acgtttctat cataagggaa agaaccttgc
     4501 ttatcagcat gaacttcttc cgttattaac caaccacgag cagcaagcaa gtagttattt
     4561 aacaaaaatc gttcataaag actacgcttt agctgtcaaa gaacttgaga atttcttcac
     4621 gacgatattg gaacagccta ttgatccagc ttatttgaaa catgaggcaa tcaatcgttt
     4681 ctatgcatta ctcaacgctt tggctgacga gcatgttggg aatgaagaac tttctttgct
     4741 caagatcgcc cttccttctt tattagccga tgctgagtat ttcgaagatt tttctattct
     4801 tgtcaaagaa acacttgaga aactcaccca cttttctgca aatgcaaaaa aagacaattt
     4861 cgatatcttg actttgatct acgagttcgt ccaggaaaat tatgagaaag aaatcaattt
     4921 acaactttta tccgaaaaat atcatttttc atatagctat ctctcagcca tctttactga
     4981 aaaatttggt atcaactttt caaaatatct aaaaaaagtc cgtatcagta aagccaagct
     5041 ctttttgacg gaaacacggc ttactttgac ggaaatctgt gagaaagtcg gctataccga
     5101 actgggttat ttctccagag tttttaaaga agagacagga atgacacctt ctcaataccg
     5161 taaaggaact tttgtaaaat gagaaaaaaa atcaaagagc atgaactctt tgccaaactt
     5221 ctgttcattt tgttcatcgg tctttttctg caagccatcg tcatttcttt gtttatttat
     5281 catcgatcaa gggatgccta tatccagctg ttcaatcaat cgaatgatgt ggtactaaaa
     5341 aagattcaat ctgaatttga aagtttgaat gatacaatcg agaatacatt agccgctttt
     5401 gattctaatc cagctgtcaa aagctatttt tccaatgatc cagcccaaca tatggaacag
     5461 cttcagcaac taagaacaat ccaaaaaatg aatgactctc tttcaaaaat ccatccaatg
     5521 atcgattacg atgtattgat ctttggagaa aatggaagaa cttttgtcgg aaacgacatg
     5581 ctcactgccg tatctgccga ttcttttttt caatctgcga ttgctcagag agtgaatgaa
     5641 cgtgctgctg atacacaaat gctttttgca caccacggat tgactcttcg cgataagaaa
     5701 gcacccagcg tcttctttgt caaaaaactg aaaaatacat tgaatcacgt ttacggatat
     5761 gctgttttat cgatctcatc caagcaacta gcgaatcttt ttcaatctgt agtaaatcct
     5821 gagatatcga agatctcctt catgaacgaa gaacagacga tcatcgcatc aaatgaagaa
     5881 aatacaattg ggagccgatc aatgattttc aaaaaactaa cagtaggtga aacaacgatt
     5941 tcaaatggac agcagttgac ccgtcttcct ctgtaccgcc aggattgtac attactcagt
     6001 caagtcgatc ttcattcttt atctaaccaa atgggcgtga tttttccgat tattttgtat
     6061 aatatcgtga cacttgcttt tgctggctca ttggtattta tgtatttgga tcgacacaca
     6121 aaatcgatct accgcttgat tgattcgcta aaacggctag aggaagatgg cttaaaagct
     6181 actgttcctg tacaaggaag ccatgaagtc caattgctag ggaatacgat caatcaattg
     6241 ctaagtaatg ctcagcatca ttatgaacag acgatccaag acgaaaagaa gaaacgttcg
     6301 cttgaaatcc aaactatgca agcacagata cagccccatt ttatttataa tacgctgact
     6361 agcttgaaat ttttgatttg gcagaaaaaa acagatgaag cagttcaagg aatcgacagt
     6421 ttcattactt tactaagaag tacgattggg aaaaaagaag aagtgattcc agtcaaggaa
     6481 gaaatcaaaa gcgtacaaag ttacatcgat cttttgagta tgcgatatgg cgaaagaatc
     6541 tcggctaaaa taatgattcc tgatgaactg cagtcattat ctatgccgaa tatgatcctt
     6601 caaccaatta tcgaaaacgc ctatcttcat gcttttcaca ataaaacgca aggattcatc
     6661 acggtgtacg gcaaaacaaa aaatcagctt cttttattcg aagtgattga taacggcgat
     6721 ggcttcgata ctgaaaatac caaacaaaaa aatgatcatt tttcaggaat cggcatcagc
     6781 catgtagatg agcggatacg cctaatgtat ggcgatgcat atggcttaac gatccaatca
     6841 gtgattggga caggaacgac tgtaacgatt tgtctaccgc ttcttcctaa aaatcaatca
     6901 gaatatcaaa aataaagaat agccaagcgc tgattttttt attttaagtt aaataaatca
     6961 atcagtattc ttgactttca tctacgcgtc tcttctactg tcagcactgg ataacagccc
     7021 aatatttgac tttctcctcc gagcatcttg atttcttgga gcgcattctc tactaatgtc
     7081 attggacggt ccaacaacaa atcgatcacg aaaaaatatt ctcccaagct agttttcaat
     7141 ggtcgggatt caatcttact taagttgatt tcccgccagc caaaagctgc cagcatttta
     7201 tgaagcatcc ctggccgatt agcaggtagt gtcaagatga cactcatttt tactggagct
     7261 gactgctggc tggtcatctt tcggtcaccg acgatccaaa aacgtgtctg gttcaactca
     7321 ttatcttgga tattctcagc taagatctcc aatccaacat gctgtgctgt ttctaatgaa
     7381 gcaatcgctg ctgcgtcttc tttcggatgt tctgctacat acattgctgc agcagttgtt
     7441 gattctgttg ctactaaagg aacattagga taatgcgttt ctaaaaactg ttgtgattgt
     7501 gctagtgctt gtggatgtga aaggattttt gtaatctttg ttgctggatt gcctaaaagc
     7561 tgctgcttga taggaagaac gatttcactt ttaacttcga cttctggatg tttggaaaga
     7621 agatcgattg tgtgatgaac agctccttcc aatgaattct ctacaggaac gacagccaga
     7681 tcgacttgtt tgcgaaacaa agcgcgcaaa caaacaggga tggaagcata cgcagtcaat
     7741 tgttctgtag gaaatagctg acaagccgcc tgataagtga atgaactttc tggccctaga
     7801 tagctgacgt tcatatgctt ttgatccttt ctataatggt atcgatgatc ttttctggtg
     7861 tttgattggt cgtgttgatt cgatgtgtcg cactttcttc ataccaagaa agtcgttgtg
     7921 ccaataatgc ttttatttct tctcttgttt ttccaagagc taaaggtcga atagacgttt
     7981 catcttgttg gatacgatca actagacagt ccgcttctgc ctctaagtaa agaacaatcg
     8041 gctgtgtttt taaaaaacgc cgattttctg cactttggac aatccctcca ccagtcgcga
     8101 taattttgtc ttcatttgac agctttctta aaatatctga ctccactttt cgaaagcttt
     8161 tttcaccgta atagtgaaaa tattcggcaa tcgacaattg gatatgttcc tcaatctttg
     8221 tatctaaatc tacatactct ttttgtaaac attgagctaa ccctttaccg attgttgttt
     8281 ttccagcgcc catgaaacca atcagcaaaa tgctagccat gagcttctcc tcctgacaca
     8341 agttctgcta aatcgtcaaa aaatgccgga taagagattg aaacagcttc agctccttct
     8401 agttcgcaag gtccatcagc tatcaaagca gctacttgca gcatcatacc gattcgatga
     8461 tcgcctctgc tggacacttt tgcgccatgc agaggtgtcg gcccatggat gatcagaccg
     8521 tctgctgtcg cttttatctt tgctcccatt ttctgtaatt cttctgccac cgcatcaatt
     8581 ctgttggttt cttttacttt taattcttct gcgtctttga tgatcgtgat tccttctgct
     8641 tgagtagcca ctaaagctag aatgggcaat tcatcaatca gacgcggaat gatttctcca
     8701 ccaatcgttg ctttcttcaa atgactcgtc ttgacactta aatcagccga ttggttctgt
     8761 tcattgtgat tcgtctgggt aatcgctgcg cccatctcct ccaacacatc taagatacca
     8821 gttcttgttg gattgacccc gacatttttt aacaacagtt ggctttccgg aacaagaagt
     8881 cctgctgcta gaaagaaagc agctgatgaa atatcacctg gaacagttat ctgttgacca
     8941 gttaattttt gcggtccggt cactatgatc gttttatctt ccactgtgat ccttccgcca
     9001 aattgacgaa tcatttcttc cgtatggtta cgggaacgtt ctttttcaac gattacggat
     9061 gtgccttctg cttgtaatgc cgcaaacagc aaagcagatt tgacttgcgc actggctaca
     9121 ggcatattgt atcggatagg tgataaagag cgggttcctg tcacagtgat tggtagatac
     9181 tggtcatttt cttctccttg caagtcagcg cccatctcgc gtaaaggttc catcactcgc
     9241 cccattggac gtttagacaa cgaagcatcc ccgaacagag tagtcgtaaa aggctgtcca
     9301 gccaaaatac ccatcaataa acgtatggtc gtaccggagt ttcccatgtc aattgattcg
     9361 gttggttgga caaatgagtg gctaccgcga ccatgaatct tgatcacctc ttcctcttct
     9421 tcgatctcga cacctaattg ttggaaggca tgtaaagtac tcagacaatc ttctgcgcgc
     9481 aaaaaatttt gtatagtcgt cgttccttca gcaattgctc caaacatgat gctgcgatgg
     9541 gaaattgatt tatctgctgg tatcctaaca gtccctctta atccatgtat ttgttgtaat
     9601 aattgcattt atccagcctc ctatttgatc cagcaatgat aactggtatt agacataatg
     9661 attctttttg cttgtaacaa atcctgttgg tttttaaaac tgatttgcag tattcctaaa
     9721 atatcttccc tggtctcttg gatcttcaaa ttaatcaaag aaactcccgc ttttccgatc
     9781 agtccagtta cttctgcaat aacgccaggt tcatctggca catcgataaa taaatcaaaa
     9841 aaggcaggaa tcgcgccttg cttatggaca ggcaactggt ctcgactttc ttttgcccga
     9901 ttgaaaaaag aaaagatttc cgattggttc tcagtcatga tccattctgc tatttgtgtc
     9961 atttcttgtt gccaatctgc caatcgttcc aataatatct gcttattgct caacaaaata
    10021 tctgtccaca tgacaggatc tgaggaagcg atcctagtga tatctcgaaa gcctcctgct
    10081 gccagttgtt tggctcgcgg atactcttga ttgaattgtt ctgcctgatt gactaagcca
    10141 gctgccagaa tatgtggaaa atgacttagc attcctgtta tacggtcatg ttctcttgct
    10201 gtaagagtta catattttgc tttggttccg caaaatagtt cttgcagttt ttcaacatct
    10261 tttttcgtct tttccaaagg tgtaaagatg taataggcat tttcaaatag tttagcatct
    10321 gctgcctgta tacctgattt atgagaacca gccattggat gtccaccgac aaaccgaaga
    10381 tttttctgct cagcggatgt cacgacttgc tgcttcgtac tgctgacatc cgtaatgatg
    10441 acgtgatcag acaagttgat tctttcaagg acatcaagat aagctaaggt tgtacggacg
    10501 ggaacggcta ataagataac gtctgcttgt tctgcacctg tttcaaaatc acttgcaacg
    10561 taatcaacga tctgctgttc tactgcttgc tcacgggttt ttgactgact atcccaacca
    10621 actactatca gttctggatt ggtctgacga atacaaagtg ccatagaagc accaatcagt
    10681 ccaagcccca cgataaaaac atgttgtgcc atcttatttg cccccttttt agtaatgttt
    10741 caagtagtca cggtactcct tcactgcagc tttcaactca acaagcgaat cacttgggaa
    10801 ttttgacaat agctctgtcg ctaccacagt ggctacaaca ttttccgcaa cgacgctagc
    10861 tgcaggaact gctgtactat ccgaacgttc tacacttgct ttgtaaggtt cttttgtatc
    10921 gatatcaaca ctttgaagtg gcttgtacaa tgtaggaatg ggtttcatga ccccgcgaat
    10981 gacaagtggt tcgccattgg tcattccgcc ttcgaagccg cctagattat tggtacgtcg
    11041 gaaatagcct ctttcttctt cccataggat ctcatccatc acttctgagc ctggtaatga
    11101 accagaagtg aatccgaccc caaattctac gcctttaaag gcattgatac taaccacagc
    11161 ttgtgcgatt ttggcatcta gcttcgtgtc ccattgtacg tagcttccta atccagctgg
    11221 aacgcctcca acgagcactt ctacaattcc tccgatcgta tctccatttt tctttgtctg
    11281 atcgatcaaa tcttttattc tttgctcaac tgctggatca acaactcgta cttctgacgc
    11341 ttcagaaatt tctttgattt cttgaatcga gatatttcca ggtatttctg cttggattcc
    11401 accaagacaa atcacgtgtc ctgctacgat gatgtcaagt tcttccagaa ttttcttggc
    11461 aattgcgccg attgctacac gcatggtcgt ctctcttgca gaggaccgtt caagcacatt
    11521 ccgaagatct cgatgatggt atttcatacc gcctaccaaa tccgcgtgtc ctggacgcgg
    11581 acgtgcaact cgccgcagtg attggtcttt ttcaggcact tctgctacag acatgacagt
    11641 tgtccaattt ttccaatctt tattttctac cactaaagtg acaggtgaac caattgtttt
    11701 gccgtgacgg atgccagacg tgatccgaac acgatctttt tcgatcttca tccttcctcc
    11761 tctgccgtaa ccagcttgtc tgcgagcgag ttcgtgattg atttcttctt ctgacagagg
    11821 taatcctgct ggtagtcctt caataatggc tgttaattct ggtccatggg attctcccgc
    11881 agtcatataa cgcatcttac agtcctccta agtaatcttt gaatgtctct gtgggaacag
    11941 gaacgatttt tgcttgccca atcttttcta gcaagatgat attcaattgg cttcctcttg
    12001 ctttcttatc atgggttatc gcgtggaata attcatctgg atgacttaga tcgtacgtaa
    12061 tcggcagatg gaatttttga agtatccttt ctaaagcagc tgtcgatcca gttggagaca
    12121 agccgatttt ttctgcatga gaagtgatgg ctaccattcc aatagctact ccttctccat
    12181 gactgactac cccatatcct gctgtatttt caattgcatg gccaattgta tgaccaaaat
    12241 ttaaaataag tcgatttcct tggtcaaaga catcttcttc cactactttt cgtttgattt
    12301 ccaacgtagc agtaatgatt ggaacagcat gttccagaag atctttttcg tctttcagct
    12361 cgttcagctg tttccaaagc gttgcatctg ctatagctgc tgatttgatg atttcagcga
    12421 ttccttctcg taaacgacgt accggcaaag tttttagaac ctcaggatca atcaatacac
    12481 cagctggctg gctaaatgtt ccgacaaggt ttttcgcttt gtttgtattg actgctgtct
    12541 tcccgccaat actagaatct acttgtgcaa gtagcgtagt cggaatttga acgaaatgga
    12601 tcccacgcat gaacgtcgag gccacgaatg ctgctagatc acccaccatt cctccaccaa
    12661 gtgcaagtat cccatcgctg cgggtaaaat cattatctgc taaaaaatcg tataactcag
    12721 ctgcttgttc taaagattta ctggtctcac ccgccggtac gattgaaagg actggttcaa
    12781 aattagcttg tctcaattgg aacatgattt tttctgcata tagtggagca acgtttgtat
    12841 cagtgatcac agctactttt tgaggtctcc aaatcgtttg aagccatgat ccagcctgtt
    12901 ctagtgcgcc tttttcaata tgaatatcgt atttttggtt atcaacatgt acagtaagca
    12961 ttcgtttcac ttctttcttt taaaaagctg gaattaatcg agtgtctgaa tcttttccat
    13021 tgcttctttc atgatcgcaa cttctttcat catgcgtgag taagtctttt cattcaacga
    13081 ttggggaccg tctgaccaag catttgcagg atcaggatgg atctctacga tcatgccatc
    13141 tgctccgctt gccacacccg cacgagccat tggtggtaca agttcccaaa ttcctgtacc
    13201 atgacttgga tcaacaatca cagggaaatg agttaatttt ttcatcaatg ggacagcact
    13261 taaatcaaac gtattacgtg tcgctgtttc gtaagtccga atcccacgtt cgataaaaat
    13321 gacaggagat ttgtcttcga ctgcaatgta ttctgcagca ttaagccatt cattgatcgt
    13381 accggaaatt ccacgtttca atccaacagg tttacctgtt ttaccgacag cagatagcag
    13441 tttaaaattt tgcatattac gtgcgccaat ctgtaggata tcgctgtact cagccaccat
    13501 atcgatatgc ccttcatcca tcacttcagt aatcactttc attccaaatt catcagccgc
    13561 ttgacggatg tatttcaatc cttcttcttc taaaccttgg aaagcatatg gagaagtacg
    13621 tggtttgaag gcaccacctc gcagaatttt tgcgcccccg gctttggcca ttcgcgcaca
    13681 ttctctgatt tggtctaatc cttcgataga acaaggacca gccatcgtca cgaaactgcc
    13741 gtcaccaatt tttactccgt ctacatccac gactgtattg ccaggatgga attctcgaga
    13801 agtcaatttg tatgtgttta aaatacgcac agcattttct actccttcat agcgtgtaaa
    13861 tgctccttct tgtaaacttc gcgtatcacc ttttagtcca atcactactc gttctgttcc
    13921 ttgatcgatt gagactttga atccttcttt ttcgatatga tcgacgactt tttttatttg
    13981 ttcttccgtt gcttcttttt tcataattac tatcattgtt tttcccgctt tcttttgttt
    14041 acttatctat cttggctgat tttctctact ttttcaaggt ggttttacat taattcctac
    14101 taaatgaccg tgtcctgttg ttctcatttt cgctccttct ttcctactta tgacccagat
    14161 aatcaacaaa aaaagatgtc cctgtaggaa attgcctcta cagtgaacat cttcaacgag
    14221 ccttaaaaag cgctgcaaaa atataaaata gccactatag atgaatttct ctacgtggct
    14281 gtaagtcgtg tttaaaaatc tttagccatc atagatacaa acctggtttg tttgtaccca
    14341 cgaagtcatg aatacaaacc tatctaaaat agctaaagta atacgtattc agttttgtaa
    14401 gttttctaga tttcataaaa aatcgctcca aactgatgta agaattgtac ctagtataga
    14461 cataaaaaaa tcgactgtca atcattttta tgaaactttt tttaattttc tgatagttaa
    14521 ctttgttttt cagaaaaata acaattggtt ttattgaaga aaatagtcat gaacaaaagt
    14581 atctgagaac ttttttactc tcttgttcat gacatataga ataaagcagc tttgtcttgt
    14641 aaactccgtt tttcaaataa taatctaaag attgctactg aataataaag ccgatttcat
    14701 ggtcctcttc gctgctgatt cggtaaggtg actcaacatc cgctccccag ctattgatac
    14761 ccccgactcc tcttactttt gcaaaaatcg taagaaccgt tcgtctttct ggcggtagtt
    14821 cttctatatg tgttgcctgt tccagttctt ctgctttgaa tggtaaagcg gaaaaagcaa
    14881 atggcgtatc ctgctgttca aatcgcaacg aaaaatcttc ttgatcttta tccgtattat
    14941 ccaacgtttg atttcttgtt agttctaccc atttcgtttc catatgcatg ccgcattctt
    15001 ggggaacaag gtatggggaa acggggagtc ctgccacttt ataaatacct tcgacaccac
    15061 cagccatccg atccggatat gtttcccctg ataggccttc atactcaaaa aattttgctt
    15121 tcgttggcat aatgaacctt aaacccaatg cgggtaattc cggtaatcct ttttgtccat
    15181 aataatgcat attgacaagc attttaccct ctccagcgat ttggtaggaa attgtcactt
    15241 gggtttttgg tactgtgttg atttccagtg taaaaatgat ttcaaccgtt tcagcgtatt
    15301 cattacttga atattgatta tttactggag caatcggcaa atcgatcttt ttattgtcca
    15361 ccagtacttc tatttctttg acttttggat acaatccggc tcctaaccac ataccggatt
    15421 taaatccaaa tccgctacct ctgtcattat cggtcgttgc tcgccaaaaa actggaagtg
    15481 tttcccggta tagccattct tttccgtttt tattgagcga ttccagtccg cctcttgtat
    15541 aagaaaaaat ataatgcgta ttccccgatt tgacacctaa tgtacagtcg ccgaagacga
    15601 ttgcaacttt ttccgtatcc atatgacttt tatttactgt atttttcata ataatatctt
    15661 acctcctgca tggcgggttt ttcttgtcca tctgcaaaaa cgatcccatt ccctgagaat
    15721 tcatagtcac ttggtttatc gtcaaagtca ccgccatagc gcatcacttc tctgcctgtg
    15781 attggatcag tcacttggat cgcctgatct ttaaaatccc atatatagcc tccttggtac
    15841 atttcataac gatcaagcaa cgtcatgtaa gaatccattc cacctaacga attccccatg
    15901 tcatgcatat attcacataa gatgaacggt ttttccgctt tattttcaag gtagtcaatg
    15961 atctcttctg gtggcgcata catgcagctt tttacatctg aaatcgaatc ttcgaatgct
    16021 ggatttggaa aattcccttc ataatggaca agtcgatcgg ggtctacttt tttgaagtaa
    16081 tcgttcattt gtcgaatgtt ttcttccgca taagattcat ttccaagaga ccaaaaaaga
    16141 atacttggat ggttttttaa tgtttcgaaa ttcgtttttg ctcgatcaag aacagccgcc
    16201 tgccactgag gtactgcacc tggtacgttg taagaaggct caaatgcgcc cattttttgc
    16261 catgagccat gggattcgag gttcgtttcc gccatcacat ggattcctgc ttggtcgcat
    16321 aaataatacc aagtgatctg gttggggtaa tgagatgtcc gtacgccgtt gatctttgca
    16381 ttttttatga tagccaaatc tttttccata tcttctatag tgatggcgcg tccttttttc
    16441 ggatgccact catgtcgatt taccccgttg ataatcatcc gttttccatt gaagtagatg
    16501 attttatctt tgatttcgat tttacgaaaa ccgaaggaat agtcaatata ctccgttact
    16561 cttttttctt cgtctatcgt ctccaattca agcttatata aattgggctg aaaatgcccc
    16621 cacagtgcca cattttcaaa tccatcgatg cgaatcgtca tttgctcttt taacggatat
    16681 tgctgttgat agatttcctt cccatcagga tctagtatcg ctacattcag ctgactgttt
    16741 ttggctactt gctcaaaaga caaatctact tcaagtttgc cattttgaca tttgtcatct
    16801 aagcgaggtt tgatccaaag atcttctaaa tggttttgtc ctcgagcaac taagaagaca
    16861 tctctgaaga tcccaaaaaa tcggaaaaag tcctgatctt ccaagaatgc agctgtactt
    16921 cttttgtaaa cctccacagc tagaatattt tcttcttcca aataaggtgt taaatcaaat
    16981 tcagacggag tgaacgaatc ttcggcatac ccgataaaat gaccattcaa ccaaataaac
    17041 attgcttgtt ctacaccagc aaaatgaatc gagatttgtt ttccctttag accttcttct
    17101 aatcgaaaag tcgtcaaata cgaaccaacc ggattgtctt tagcagctga aaagatccct
    17161 tccgcctctt tctcagggct tgtcgtgaaa gggggacggc gaaatacatg tccctcccac
    17221 ggatacatcg tattgatgta atggatcttg tcataatttg ctaattcaat atgactagga
    17281 acagtgattt catcaaaaga acaggcatca aaatcttttt tataaaatgt ttttggtcgt
    17341 accgaaggat ttggcgaata acaaaaacgc catgatccat ttaaagactg tttaagggag
    17401 gatgtggttt ctacttcttc ccttgttgca taacaaacat gatcgctatg tgcatttgat
    17461 tggttcactc taaaaacttg tggatcatct aaccatttta tatttgcttt catacttttt
    17521 tccttctctc tcataacttt ttgaaatgaa gcagttctgt ttggaaatca ccttgaaaat
    17581 cggggaagta aagtccaact gtcatcaatt cggcccccga aaatatccgc ttcgaggtct
    17641 gttcctgata aagtgcctca tcatctaacc ccatcagata tacttcatgg aacgctggtt
    17701 gagctgaagc tagtatcctc cctaaaaaca caatagcttc atcttgttta ggagacacaa
    17761 acatccatgc ggcaatattt tcttcaaaag gactcgccaa acgataataa tggccatact
    17821 ggatcaccgg acgaatcgtt tgataggata taatttggtc ttttacttgc tttttttctt
    17881 caggagacag ctttgtcaaa tccagttcat aaccaaaaac agcgctcata gctgtttctc
    17941 ctcttgtttt caacgaagta gatctgtcgg tctgatgatt tggtacagct gatacatgag
    18001 ctgtgatgga cgaaatcgga taagcaaggc ttgttccata ttggattttc atacgctcca
    18061 ctgcatccgt gttatcactt gtccatgact gcggcatata ataaataaac ccggcatcaa
    18121 accgtccacc tccaccagaa cagccttccc ataagatttc cggataatca gttgtcaaat
    18181 gttcaagtag ttcataaagc ccgagcatat aacgatgcgc tacttctcct tgtctctgtg
    18241 ggtcaagggt aatcgaatag acatctgaaa gcgaacggtt catatcccat ttgatgtagt
    18301 caagaggaat cgtatctaaa atctttctca tttgtttctc aatcgtctgc cgaacatcta
    18361 accttgtaaa atccagtaca tgttgtgatc tggaagcaga aggcattcta cctggctcct
    18421 gcataagaaa atcaggatgt gttcgataca gttcagaatc aaccgagatc atttcaggtt
    18481 caaaccataa accaaatttc aatcctttgc tatgagcata atctgctatt tcacgtaatc
    18541 catttgtcaa cttgccttca tactcgaacc agtctcctaa tgaagaattg tccgcatctc
    18601 tttttccaaa ccagccatca tctaatacga acatttcgat gcctagctcc tttgcttcat
    18661 caatgatcgc cttgattttt tcactattga agtcaaagta agtggcttcc cagttattga
    18721 ccagaatcgg ccgttcagca aattgatgac gacctcttgc gattctttca cgtagcaact
    18781 catggtggat ctgactcatt ttgttcaatc cctgacttga gtaagaaagg atcatttcag
    18841 gtgtttgaaa agactggcct gcattcaatt cccacgaaaa acgatggctg ttgatcccac
    18901 cgacgactct caattgattg atctgatctt tttcaagttc gaaagaatgg ttgccggaat
    18961 aaacaaattg aagtccgatc gcttctccag tattttctgt cgtatgatga tgaactaaag
    19021 caataaagtt attcatatgg tgactgctcg ttcctcgacg gctttcaaat acttttgttc
    19081 cagataaaac agattgccgt gaaatctgtc tttcattgac atgtgctcct ggcaaagcaa
    19141 tgacttcatc aaatcgccta gtatgggcaa agtctagctg gaaactagcc gctttttcta
    19201 gtttgattgt ttctccggtt tcatttctta tctttacaga tcgtgtgatc actgctctat
    19261 cagtaaatat ggtatagaac aaatcgaaat aaatcgctgt ttctctatcc ttaagtgaaa
    19321 tcaccaacgt ttgtgcctct gacttgtcca tcacataagt ttgaggcaag ccttcgatct
    19381 ctggcttccc atctgtaata taatggctgt catatctcag atccagtaag tctgatccat
    19441 tcttgcgctg aatgatcgat gcgggcgttc gaaagtccat gctgccatga gaagagtatt
    19501 cttgcggtag tgtatctttc gacagagacc ggtcaggatt taagggaaca tttcctgaaa
    19561 atccacgatc tcttcgggga taatttttat tgtctttgta ctgcttgact ggtttgccaa
    19621 aataaatatg cgccaataca ttgctttctt ctatctttat cagataagaa agaaatgtat
    19681 ttcgtaaatg gaagactcgg ctcttttcat caaataagat gaaattttta tctgtttttc
    19741 tatgcgtaat atccatcatt tcactcccaa caaaacggaa accgtttact tttttttata
    19801 attcctgtat actgtttact aaacaatttt gtcaataaaa attttttatt tttttgagga
    19861 gtgtgtaaaa atggttggaa ttagagatgt cgcacgaaag gcaaatgtct ctcctgctac
    19921 agtttcccgt gtgttgaata acgatcagac gatccatgtg gctcagacta ctcggcaacg
    19981 gatagtagag gcagctgctg cgttggatta tgacatcagt actcgtaaat atatcaaaaa
    20041 gagaatgcct tcgattggtg tgatctctac gatcggcaaa gcgagcgaag aacaggatat
    20101 ctattacaaa catttgcgag tagggatgga agaagaagct cgacgtctgc atttagggat
    20161 gaatcgaatc tataatctat ctgataatcc taaacaatgg gaagatctag atcagttagg
    20221 tgcggtgatc gttgttggga ctgttacgaa agaatcgatt accgccttgt taaaacaaaa
    20281 catgcaaata gtcgtcgtgg ataaccctga catccagcaa gaggtcgata tggtgtatgc
    20341 agatcttgaa cggatgacta aaaccgtact ggaattgttc ttagaaaatg gtcataaaag
    20401 aatagcctat atcgggggat ataaagtcga tatggatgaa ttcggtggga agcagatttc
    20461 tataaatgaa aagaggatgc gtgcctatca gcattttatg atcgatcatc acttagaaaa
    20521 atatatgtct tatcatctag gtggctggac agaaaaacaa ggtgaggtac ttgcgactaa
    20581 tctattagaa aatgaatccc ctcttcctac tgccattctt gtcgggagcg atccaatggc
    20641 aattggtgtc tatcgggcat tgaaacaaaa aaatatccaa attggagaag agattgttgt
    20701 agcaagcttt gataatatcg agacaatcgc aaacctctcc cctggcttga ccagtgttca
    20761 aatcaatgcg aaatcaattg ggcaagcagc tgttcgaatg gcattggagc gaattgacgg
    20821 tatacgggac gaaccaatca ttttgactta tcctgcacga ttgattgtta gggaaagttt
    20881 tatcccaaga acaaaaaggt attgaaagag aggttgtgaa aagccgcttc gtttcttcat
    20941 actcaaaacg aaacggcttt ttcacaacct cttacttata cttattcaca aaatccaatg
    21001 tctgctggta acaattttgc gattctttta gcgtgtaatc aaattggtat tcatgggtaa
    21061 tctctttttt tgtatctgta taaaacaagg attgcacggg tacctttaat tctgtcaacc
    21121 gattttctaa tgcttgacct tgctcctgga atgagtatgc atttccgtca gttatatacg
    21181 ttggcggaaa ttccttagaa acatggtcag ccacactagc ttctttcaat tgctcactcg
    21241 ttttccaatc ttttgttcca atcaacgacc acgcaacggt tttgacgaaa aacttcataa
    21301 atcgatcatc cgaatgctgc tgtgctgtta gcttcaaatc aacaggtccg caataagaaa
    21361 tggttccttt cagactatct tttggaagta gctgtttgat tttcatttgt ttagcatacg
    21421 catcattcgt ttgtatagct gcatattgca atgcgatttg tgaacctgca ctatctccac
    21481 caaaaaataa ttgttccatg tctagcaatt tgtcgtcttt ttcttcagct aataaatctt
    21541 tgatcagttc attcacttga agaacttgat tagggtattc tgaatcaggc gctaattcat
    21601 aattcatcgc aaccactgcg atgttggcgt ctgaaactaa ttttgtcgca aattctttga
    21661 cacccgattt atctccgccg acgaatcctc caccatgtac ccaaaataga acaggaacag
    21721 gccccttgct gttttttgga tagtagatgt cataagtatt ctctttatac ttggactcat
    21781 acgtcaaatc tgtttttttc gccacgtttt tttctgcttg atcgaacgtt tttttatcag
    21841 tgatttgaac agtatttgaa aacatatggt tgatcaagaa tgctccaggt ctgggggaaa
    21901 gctggaaggc aagaaagatt gcaaacgcga tcccaagaat gattccgaag aaccatccga
    21961 taaatttaag aattttcttt ttcataaggc tccctcagta gttagtatta agcattctga
    22021 ttataccata gtgttatttc ctatcaagct ctcctagatg atttaatgat tttccccaaa
    22081 cttcttctgc aatgcttttg acaaaagaaa ttttttccat tgttcttcaa acaaaacatt
    22141 ttcttcttct gttgaagcaa atccacattg aggacttaag cacaaacgat ccaaaggcag
    22201 atatcgtgtc gcttcgtaga tccggtcaat cacttgctgg tgctcttcca tttcgccatt
    22261 tttcgttaca gtcaaaatct aagacaacta atttatcttc agagactttc tctaaaagaa
    22321 caaaactccc agcacgttca ctatcgtatt ctaaataata ggcacggaca ttttcttgag
    22381 taaaataatg ggtctgctac gtcgtcatcc cccctgatgc cgccaaaatc gaataataat
    22441 ttccgcgtca aacatgtata tttagtgttg aatcatttga gaatatgaaa ataaaaatct
    22501 ttttgatcaa tcagttaatc aaattgaaat aacgaaaaat ctgagacaga atgacgttca
    22561 ttctgaccca gatttgattt tgcacaactc aacagtcctt attggcaaat cgccaaaata
    22621 atgtagacta actaaaaaga ctaagaaaca ataacaaaag ttaacacttc ttagtctttc
    22681 tttagcacgt ctatttatta aagattttag ggccttttct catgttttta cgatcattct
    22741 taggtgtttc catttgtttg gatcggcctc caccttgttt ctttttgatc aattctttca
    22801 ttttttcttt ttggtccatt tttattctcc tttaacgaat gaagcgacta attcgatatg
    22861 atgggtttgc gggaaaagat ctacaggctg aactttcttc acggcataac ctgcttctgc
    22921 aaataactta gcatctcttg caaaagttgc cggattacat gagatataga cgattcgttc
    22981 tggtgacatt tcgattgctg attcaataaa atgatgatct aatccttttc gtggagggtc
    23041 aactacgatc acagatggtt tgatcccttt ttcttgccat tttttcataa ctttttctgc
    23101 ttttccgact tcataatgaa cattttcgat tttattattt aaagcattga actgtgcatc
    23161 ttcaattgct tctggaataa cttccatccc atacacctta tccactctgt ctgctaaaga
    23221 caagccaatc gtacctattc ctgaataagc gtcgatcaca atgtcttttt tatctaactc
    23281 ggcaaactcg atggctgttt ggtacagata ctctgcttgt tgagtattta cttgataaaa
    23341 tgactttgct gagattcgat aggtttttcc taatagctga tcttcgatat agtctctgcc
    23401 atataaaact ttttctttgt ctcctaaaat cacatttgtt ttttcttcat tgatattttg
    23461 gatgaccgaa accacttctg gcaattcttc atgaatagct tcagcaattt ccttggattt
    23521 aaagaatttt tctttacgag taactaaaac gaccatcatt tcatgggaat aatgaccacg
    23581 acggataatg atgtgacgaa gctgtccttc atttttttct tcattatatc ctcgtacttg
    23641 gaaccgttgc aagatatctc tgactacttt gattgcttga tcgatgacag gatcttggat
    23701 ataaaaatct tcgataggga ctagatcatg gctattcttt ttgtaaaaac cggtggctaa
    23761 ctgtccatcg atacggcgaa cagggatctg tgctttatta cggtagccga atggttctgc
    23821 cattccgacc gttggaagta caggaacttc tggcatctta gcaatcttcg ccattacatg
    23881 ctctacttgt ttttgtttga agacaagctg ttgttcatac ttcaaatggg ctaaaggtgc
    23941 gatacctatg cgaagtaatg cattgttttc tacaggctga cgatcaggtg attgtgtaat
    24001 aaatgtttcg acttttccat atccaaactt attgcctgct tttactacta gtatttctac
    24061 ttcttctcca gggagtgcat tttcgataaa taatggataa ccatcgattt ttgctacccc
    24121 cattccttca taactcaagt cgacgatttc gactgtatat cgttcgtttt tctttactat
    24181 ttgctgttct gtcatatttt gctcctttaa gcctattttt caatcctact gaactctact
    24241 ataaatcagc taattacaca actaaaaccg gcactgacct tactacgttc agcaccggct
    24301 tttgattaat tcttttgatt aggtgtttcg tctgctattt ttccgtcacc gtcgatatct
    24361 tcatccgtta aacgttcgac ttcttttacg aattctttgc tgacaacctc taattcttct
    24421 tcatctgtac ctgtgattgc ttcatcagga atctgatcgg tattggcaaa gaactcaatg
    24481 tgttgatgaa gattttggaa atgcatcggt gcttccccgc cgtattcacc atctaagttg
    24541 atcattactg gtcgattgat atcatcttct gtttcaacga acaaactgct tgttttggta
    24601 tagattattc ttggatcatc gacatgtcga ccgccattca gcatgagtgc tgcaatatgc
    24661 aagatctcaa agatatttgc tgtcttcaca atgattaaag aaaacttccc atcatccaat
    24721 ttggcatctg gcgcgatctg ttcgaatcct ccaacagagt tcgtcagccc taggaaaaac
    24781 atcgaagcat ttccgatata ttccccttca tcatacttca agcgcatttt gattggcttt
    24841 actcgaggga gcatctctgc tcctttcgca agataagcaa gataaccaaa aatactcttt
    24901 agttctgatg gaacttcata agtcaattct gtcaaatagc cacctgcagc gatattgatg
    24961 aagtaactgt tatcagaaag gccgatgtcc atttttacgg tttggtgttt ttttatcact
    25021 tctgctgctg ctttaatatt atctctagga atttttaatg ctcgagcata gtcgttcgtt
    25081 gtaccagctg ggatgatggc cattttagga cggtgttcaa gcggagcgat tccattaacc
    25141 acttcgttga ttgtgccatc gccaccagct gccactacta gatcaaaacc tagttctgcg
    25201 actctacatg cttcattctt ggctgaatct ggttctggtg tagttgcata ggcgctggct
    25261 tcaaatcctg cttcttctaa tgcctgtagg atatccgcca aatttttttt caataattct
    25321 tttcccgagg tggggttata aattacgcgt gcttttttca ttttcagcct ctatcgtttc
    25381 gctaattcat ctttaagtag cttattcacg acaccaggat ttgcttgtcc tttagttgct
    25441 ttcatgattt gaccgactag gaagccaacc gcacgatctt ttccattttt gaaatcatcg
    25501 acagattgtt ggttgttatc caaaatttca ttaatgattg gcagtagttt gttcggatca
    25561 gataattgca cccaaccatt tttttcaact acttcttggg cttctccgcc atttgtgatc
    25621 aattcacgga agactttttt ggcgattttt gagctgatcg ttccatcggc gatcaaacga
    25681 atcattcctg ctaagttctc aggtgtcaat tttgtctcag ctaattccag tttctcactg
    25741 ttcaagtaag cagaaacttc acccatcaac cagttagatg cttgcttggc atctgcacca
    25801 ttttccaaaa cagcttcaaa aaaatcagac atttcttttg taagtgtcaa taccattgcg
    25861 tcatactctg gaagtccaaa ctcacggata tagcgttcgc gacgagaagc tggcatctca
    25921 ggcaaactag cttttacttt ttgaatccat tcgtcatcga tcacgaattt cgggatatca
    25981 ggctctggga agtaacgata atcactagac ccttctttga cacgcatcaa aactgtttta
    26041 ttcgttgttt cgtcaaaacg gcgtgtttct tgttggattt ctcctcctga aagaagaact
    26101 tttgcttgac gtttttcttc aaaagctaaa ccttttttca cgaaagataa agagttcaag
    26161 tttttcaatt ctgctttcgt accgaactct tcttgtccat aagggcgaag agaaatattg
    26221 gcatcacagc gcatagagcc ttcttccatt ttcacatcgc tgacttctgt aaattggata
    26281 attgatcgca atgcttctag ataagcgtat gcttcttctg gtgaacgcat atcagcttca
    26341 gaaacgattt cgatcaaagg cgtgccttgt cggttcaaat caacgtaaga ataaccgcca
    26401 ataccatgca tgttttttcc agcatcttct tctaaatgga cacgttcgat ccggattttt
    26461 ttctttttac cttctacttc gatttcgatc catccgtcat gaccgattgg ttgatcaaat
    26521 tgggaaattt gatatgcttt tggattatct gggtaaaagt aatttttccg gtcaaaatga
    26581 gtatctttag agatttcaca gtttaatgcc aaagctgctt tcatcccgaa ttccagcgca
    26641 gctttattca ttactggcag cacgcctgga taaccccagt cgatcacgtt tgtattgctg
    26701 tttggttctg caccaaaatg agctggcgct ggagagaaaa tttttgagtt ggtttttaac
    26761 tcgacgtgga cttctagtcc aatgactgtt tcaaaattca ttcgtctttc cctcctaaaa
    26821 tagctggttg ttgtttatgg aattctgttg cttgttcaaa cgcatatgcc gcttgataca
    26881 tcgttttttc atcaaaataa ttaccgatga tctgcaatcc aactggtaat ccttctgata
    26941 aacctgccgg tacagacata cctggaagtc cagccaagtt gacagggatc gttaagatgt
    27001 cactcatgta cattgtgatt ggatcgttaa tgttctcacc gattccgaat gcaactgttg
    27061 gtgaagatgg cccgatgatc aagtcataat ctgcaaagac tttttcaaaa tctcgtttga
    27121 tcaatgtacg gacttgtcct gcttttttga agtaagcgtc ataataaccc gcgcttaagg
    27181 agaatgtacc taacatgata cggcgtttta cttcttcacc gaatccttct gaacgtgagt
    27241 tgacatatac atcatctaat gatttcacat tttcagagcg ataaccgtag cggataccat
    27301 cgaatcgttg caaattggaa cttgcttctg atgaggcaat gatataataa acagccacac
    27361 cgtattttga atgaggcaag ctgacttctt ccacaacagc acctaatgaa cggaatgttt
    27421 ctgctgcttt caatacagct tcttttacgc caggggccac accttcgcct aagtattctt
    27481 taggtaaagc aatcttcatt cctttgatgt cgcctgtcag tccctctgca aaatcaggaa
    27541 ctgaaacgcc tgaagaagta ccgtcttttt cgtcataacc gctgatagct gtcaatgcta
    27601 atgcattatc tttcaccgta cgggtcattg gtccgatttg gtcaagagat gaagcaaagg
    27661 caatcaaacc aaaacgtgag acacggccat aagtaggttt catccctacg atgccgttaa
    27721 aagctgctgg ttggcggata cttcccccag tatcactacc taaagaaact ggaatttgtc
    27781 cagctgcaac tgctgctgca gaaccaccag aagagccacc aggtactttt gttgggtccc
    27841 aagcattttt tgttttcttg aaataagaag tttctgtact tccacccata gcaaattcat
    27901 ccatgtttag cttaccaaca gggatcatat ctgcttgata gattttatcc atgaccgttg
    27961 catcataaat tggttcaaaa ttgtaaagga tcttagatgc agcggttgtc aagatatctt
    28021 ttgttacgat attatccttg ataccaattg gaataccagc aaggacgttg ctttcatcaa
    28081 tccctttttc atctaaagct tttgcctgtt ccaatgcttt ttcttcgttc aatgtaatga
    28141 atgcctcgac ctcaggctct gtttctttga ttcgttcaaa tgttgttttt gtcaaatctt
    28201 gtacagtgat ttctttcgat acaagcatat gatgcagttc ttctagagaa cgattgtgta
    28261 attctgtcat tatgcgccag cctccccatt atcgatgatt gcgggtactt tgataaagcc
    28321 gtcttctgtt tccggcacat ttttcaataa ttcatcgcgg ttccatccag cttgcgcccg
    28381 atcttgtcgc atcacgttta ctgtttcaac cacattcgac gtaaatggaa caccttccgt
    28441 atctacttct tccagcattt caaccatatc gatgatttta cctaattggt cggtaaaact
    28501 tgcaagttct tcatctgcga acgcaagttt tgctaatttg gcaacgtgtt tcacttgttc
    28561 ttcactaatc gccatactac cccttctttc taaacgagtt aaaaactttg ctctctattt
    28621 taacacaaga gtgccgtgtc tgaaattgtt tattgaaatt tgtctgaaaa aactcatttt
    28681 tcattcttct actgagcgac ttttagccaa tgcatctgcc atttgatctt ctgtccaaac
    28741 ttcgattcct aattcttgtg ctttggtcag cttgctgcca gcatcttctc ctgctaccac
    28801 gatatccgtt tttttcgata cgctaccagt cactttcccg ccaagatttt cgatcgtctc
    28861 ttttgcttct tcacgagtaa atcgtgttag tttaccagta aggactactg ttttttcttt
    28921 aaaaggagac tcgacttctt gcaattgggc atttcgaagc cctttgtatt cgaaattgac
    28981 gcctgcttgt tttaattcat tcatcaattc atggacttct tcgttactga aataagtgac
    29041 tacactgtcg gcaatgatat caccgatcgt atcaagcgca ataatcgact catagtcact
    29101 tttactcaat gtttctagat caccgaaatg ttctgctaaa atttttgctg ctttcgctcc
    29161 gacatgtcgg attcctaacc cgaaaatcaa ccgctcgacc gaattatctt tgctgttgtc
    29221 gattgctgtc aaaatattat ttgctgattt ttcttttatt ttgtccaacg tcaataactc
    29281 ttcttctgtc aatttgtaaa gatcagcaac atctgctact agttttttat catacatctg
    29341 ttctagtacg cgcggcccca acccatcgat attcatcgca tttcttgaaa caaagtggtt
    29401 caaaccttct ttcatttgag cagggcattt aggattgatg caccgtaagg ctacttcttc
    29461 atccaaatgg acaagttcac ttccacaaac tggacaatgt gtaggcaatt ggtattcttc
    29521 gctgtcttta ggtcgtttat ctaacacgac ttgcgaaact tctgggatga tgtctcccgc
    29581 tttataaatc agaactgtat ctttcaagcg gatatccttc aacttaatat aatcaccgtt
    29641 atgcaggctg gcacggctta ctgtcgttcc tgctactcgg actggtgtca tgatagctgt
    29701 tggcgttact acccctgttc gaccgactgt ccattcgatg ttttcgatta gcgtttcaac
    29761 ttcttctggc ggaaacttgt aagctgctgc ccatctcggt gctttgatag taaaaccaag
    29821 ttgatcttgt agcgagaatt cattcacttt gatgacgatt ccatcgattt catagggcaa
    29881 atccacacgt ttgtcatgat attcttcaat gtatgaccac acttcatcaa tcgaatgaca
    29941 tagacgtttt tcccgattcg tgtggaatcc aattttttct agctcttcta gcgcatcata
    30001 ctgggttttt gcttgcatag gaccgaaatc agctactgtg tataaaaaag tgtccagatt
    30061 tcttttcgct gtgattttag aatctaactg acgcaaagaa ccagctgcgg cgttccgagg
    30121 attcgcaaag atatcttttc cctctgcttc tctgtcttgg ttcaattgga caaatgaccg
    30181 ttttggcatg aaacattcgc ctcttacttc gatgttcatt ggttctttta atttgattgg
    30241 gaccgaccgg acagttttta ggttttcagt gatgttttct cctacagttc catccccgcg
    30301 agtcgcacct ctcacgaaat ttccatcttc ataacgcaaa gaaacggaaa gtccatctat
    30361 ttttagttca cagcaatagt caactacacg tcccactgct ttttgtacac gttgatcaaa
    30421 agctatcagc tcttctttgc tgaaaacgtc gttcaaactg taaagcggaa tatcatgagt
    30481 gactttttca aaaccttcta atacttttcc gcctactcgt tgagtgggag aatcagacgt
    30541 gatcaaatca ggatattgtt cctcgattgc tactaattct gcgtattctt tatcataaac
    30601 atagtcttcc actgttggtt tatcttctac gtagtattcg cgagaccatt ggttcagtct
    30661 tgtacgaagt tcttctgctc gtttagcagc ttcgtcaatc gtcatttcat gttccatcat
    30721 ttaccctcca ctactaagct ttttcaattg gcgcaaaggc agccaaaaga cgttttactc
    30781 cttgacttgg gaaagccaca tctagttcta gatccttcga cgtcccgctt actcggacga
    30841 ctgttcctag accccatttt ttgtgtttga ctttatctcc aggtttccag ctgttatttt
    30901 cccctccagt agcactttta gagggaacaa ccgctgtctc tggctgttta tagctatatg
    30961 ctgttttttt agcgaataca ggcgtttttt taggcgtagg acgcatgcct tcgatttcca
    31021 gtaactcctg atcgatttct tctacaaaac gagaaggtcg gttatattgc gtccgtccat
    31081 ataatgttct ggagaaagca tttgttaaat acaacgcttc ttctgctcgc gtgatcccca
    31141 catatgcgag acggcgttct tcctccagtt cgctttcttc catcaatgct cgagataaag
    31201 gaaaaacccc ctcttctaga ccaatcagga atacaactgg aaattctaat cctttggctg
    31261 catgcaaagt catcaatgtc acttgggaag catcttcttc taaattgtca atgtcggaaa
    31321 caagtgccag atcatttaag aagaccgtta gtttttcttc tggtgcatca gcgtcttctt
    31381 cattttgctg ttcgaattgt ttgtcgaatt cttgtgtgac cgttaaaaat tcctccaagt
    31441 tttcgatgcg tgcttgtgct tctaatgtat tttggatttt taagtcttct agatatccgc
    31501 tacgatccaa aacctctttc gtcaattctg tcactgtcaa gtatgggatc atctgagtga
    31561 cttcttggat catctctcca aatgcaccta attgctgtcc tgcttttcca ccgatatttg
    31621 ccagatccac attttgcgct gcttcaagca gtggccattc atgaagagaa gcaaaactgc
    31681 gtagtttttc gatagatcct ggtccgatgc ctcgtttggg cgaattaacg atacgctcaa
    31741 aactgattga atcttgagga tttaccagca cattcaaata cgctaaaata tctttgattt
    31801 ctttacgatc gtagaacttg tgccctccaa ccattttata aggaatattt gctttcaaca
    31861 gagtttcttc cattacacga gattgtgcgt tcgtccggta caagatggca aagtcgccgt
    31921 aattccgatg attgcttcga atctcttctt gcatccggtc tacgataaaa cgggtttcgt
    31981 ctcgttcatt atctgcacgg tagtaagtga tcttgtttcc ttctttgttt tctgtccaca
    32041 agttttttgg ttttcgattg ctattgtttt caatgacttg gtttgctgcg ctaaggatgt
    32101 ttttcgtgga gcgatagttt tgttctagca aaattactgc agcatctgga taatcttttt
    32161 caaaatccaa gatgttctgc atatctgcac cgcgccagcc gtaaatactt tgatctgcat
    32221 ctcccacgac gcacaggttc ctaaatctac ctgccaataa attgactagc gtatactgtg
    32281 cgtgatttgt atcttggtac tcatctacat gaatataatg gaatttgttt tgataatacg
    32341 tgagtgaatc aggatgttct tcaaataatc gaatcgtatt catgatcagg tcgtcaaagt
    32401 ccatacattg attatattga agctcttttt ggtaagcagc ataacatttt gccgcaatct
    32461 cttcgtaata actgccttgc atttttgcaa aatcctgagg ggtctgcagg ctgttttttg
    32521 cttgagagat tgttcctaat atacttcgag gatcatattt tttcggatca atgttcagtt
    32581 cttttagtat ccgtttcatc aaggtcagct gttcagaaga atcgatgatt gtaaagttcc
    32641 ggttataccc gataaaatca acatctcttc ttaaaatacg cacacacatc gagtgaaaag
    32701 tcgataccca gacatcttcg cctccagatg cgagaatcgc attgacacgt tctttcattt
    32761 cttttgcagc cttattggta aaagtaatcg ctaggatgtt ccaaggattg acttcttttt
    32821 cctcaatcaa ataggcaatg cggtgtgtca gcactctcgt ctttccactt cctgcacctg
    32881 ccattagcag taatggtccg tcagtgtgaa gaacagcttc tttctgacgg gggttcatcc
    32941 cgtttaataa ttcagctttg gatgacatta acaacatcct ttcttttatc aatcttgtta
    33001 attatagcat tttcttggct ttcattaaac tagctagttc aaaatcattt gtttcttttt
    33061 atggattttt ccttgtcaat tcgttgattt cgcgctaaat taaaagaaag cgaggcgttt
    33121 gaatggaaaa aaaaggaaaa atcaagaaat tagataagac tcagatatat tttattctaa
    33181 aaggaatatt tgttggactg ctgacaggaa tcgtcgttag cctgtttcga ttatctatcg
    33241 aaaagctaag cgatttagtt cgaagtatct atgaaatgag tcgggaacag ccgatttact
    33301 taattggcct agctatttgc tgcatccttg cagcattttt cgtgggttat ctggtcaaaa
    33361 atgaaccgga tatcaaggga agcgggattc cacaagtaga gggacagctt cgcggggaat
    33421 tatcaatgaa ctggttctct gttttatgga aaaagttcat tggcggtgta ctttcagttg
    33481 gtgcgggcct ttttctaggt agagaaggac cttctataca gcttggcgca tccattggac
    33541 aaggagctgg acaattgttt cggagtccat cttcagaaga aaagatttta atttctagcg
    33601 gtgcaagtag cggacttgca gcagcattca atgctcctat cgcaggatta ctctttgttt
    33661 tagaagaaat ccatcactcc ttttctccac ttgtttggct gacatcattt gcttcagcaa
    33721 tcactgctaa cttcgtctct ctttactttt tcggcttgag acctgtttta tatctaggtg
    33781 accttccttc tttgccgttg aaatattatg gttccttagt gatcttagga gtacttctag
    33841 gcatcttagg ttttatttat cagaatgtct tgctggcttt gccaaaattt tacaaccgat
    33901 tgcctttacc agcttatttt cacgggttcg ttcctttctt gctgattttg ccaattggtt
    33961 atttatggcc tagtactcta ggcggaggca atcaaatcgt tttagctttt ggacatgctt
    34021 ccttgccaat cattatgatt atcggtttgt ttgttcttcg attcgttttt tccatgattt
    34081 cttacggtgg gggtcttcca ggggggattt tccttccgat attgacattg ggggctttaa
    34141 tcggtagctt ttatggaaac attatggttg atttcgggat ggatccaatc tacatcaagg
    34201 attttgtcgt tattgccatg gctggttatt tcacagcgat tggaaaagca ccgctgacag
    34261 caattatttt agtgacagaa atggttggct ctcttaatca tctgatgcct ttaggattgg
    34321 ctgctcttgt tgcttatatc gtcaatgacc ttctcggcgg taatccaatt tacgaatcat
    34381 tattggaacg tctacttgga aatactcaga ccgcctcact aaaaggtgca aggacaactt
    34441 ttgattttcc agtaacggca gagagttctt tagacggatt aatggtacga gacttcaatt
    34501 ggcctaaaaa tatgctgcta atctctatac gcagaggaaa tcaggaaatc ttgactcacg
    34561 gtgatacgat catgaatgta ggagatattt tggttatctt gactgatgaa gcaaacttgc
    34621 caagaatcaa gcaggaaatc gaggctaaat cttctatcac aaatttgaag caatcatttt
    34681 aacgaacatg gaaaaactat tttacaacaa ctattcatct acactacttg attctatatg
    34741 attctataaa aaaagaagag gctgggaaaa
//
LOCUS       DADQDV010000026        34688 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.026, whole genome shotgun sequence.
ACCESSION   DADQDV010000026 DADQDV010000000
VERSION     DADQDV010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 34688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34688
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.026"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            591..1280
                     /locus_tag="J8S10_001323"
     CDS             591..1280
                     /locus_tag="J8S10_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAZ9629913.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1267..2475
                     /locus_tag="J8S10_001324"
     CDS             1267..2475
                     /locus_tag="J8S10_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAZ9629914.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2769..4040
                     /gene="serS"
                     /locus_tag="J8S10_001325"
     CDS             2769..4040
                     /gene="serS"
                     /locus_tag="J8S10_001325"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HAZ9629915.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="J8S10_001326"
     CDS             complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="J8S10_001326"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HAZ9629916.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6578..7273)
                     /locus_tag="J8S10_001327"
     CDS             complement(6578..7273)
                     /locus_tag="J8S10_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HAZ9629917.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="J8S10_001328"
     CDS             complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="J8S10_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HAZ9629918.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8472..8663)
                     /locus_tag="J8S10_001329"
     CDS             complement(8472..8663)
                     /locus_tag="J8S10_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HAZ9629919.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8684..9574)
                     /locus_tag="J8S10_001330"
     CDS             complement(8684..9574)
                     /locus_tag="J8S10_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HAZ9629920.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9561..10328)
                     /locus_tag="J8S10_001331"
     CDS             complement(9561..10328)
                     /locus_tag="J8S10_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAZ9629921.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="J8S10_001332"
     CDS             complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="J8S10_001332"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HAZ9629922.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="J8S10_001333"
     CDS             complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="J8S10_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HAZ9629923.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="J8S10_001334"
     CDS             complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="J8S10_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HAZ9629924.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14944..15282
                     /locus_tag="J8S10_001335"
     CDS             14944..15282
                     /locus_tag="J8S10_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629925.1"
                     /translation="MSPFRSAALEEESDPRINDVVLSTGNINQKYIVRDIVFVVECLE
                     ADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQKKRDGKYFLELFAYGT
                     VIQFIQTTIG"
     gene            complement(15450..16208)
                     /locus_tag="J8S10_001336"
     CDS             complement(15450..16208)
                     /locus_tag="J8S10_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HAZ9629926.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16226..17044)
                     /locus_tag="J8S10_001337"
     CDS             complement(16226..17044)
                     /locus_tag="J8S10_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HAZ9629927.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="J8S10_001338"
     CDS             complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="J8S10_001338"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HAZ9629928.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="J8S10_001339"
     CDS             complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="J8S10_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HAZ9629929.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18173..19507
                     /gene="dnaA"
                     /locus_tag="J8S10_001340"
     CDS             18173..19507
                     /gene="dnaA"
                     /locus_tag="J8S10_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HAZ9629930.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDIKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19705..20835
                     /gene="dnaN"
                     /locus_tag="J8S10_001341"
     CDS             19705..20835
                     /gene="dnaN"
                     /locus_tag="J8S10_001341"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HAZ9629931.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            21064..21306
                     /gene="yaaA"
                     /locus_tag="J8S10_001342"
     CDS             21064..21306
                     /gene="yaaA"
                     /locus_tag="J8S10_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HAZ9629932.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21293..22417
                     /gene="recF"
                     /locus_tag="J8S10_001343"
     CDS             21293..22417
                     /gene="recF"
                     /locus_tag="J8S10_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HAZ9629933.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQIRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDSRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22414..24360
                     /gene="gyrB"
                     /locus_tag="J8S10_001344"
     CDS             22414..24360
                     /gene="gyrB"
                     /locus_tag="J8S10_001344"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HAZ9629934.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24380..26851
                     /gene="gyrA"
                     /locus_tag="J8S10_001345"
     CDS             24380..26851
                     /gene="gyrA"
                     /locus_tag="J8S10_001345"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HAZ9629935.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDYAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKEDQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            27087..27386
                     /locus_tag="J8S10_001346"
     CDS             27087..27386
                     /locus_tag="J8S10_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HAZ9629936.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27436..27948
                     /gene="ssb"
                     /locus_tag="J8S10_001347"
     CDS             27436..27948
                     /gene="ssb"
                     /locus_tag="J8S10_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAZ9629937.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            27974..28210
                     /gene="rpsR"
                     /locus_tag="J8S10_001348"
     CDS             27974..28210
                     /gene="rpsR"
                     /locus_tag="J8S10_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HAZ9629938.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28353..30326
                     /locus_tag="J8S10_001349"
     CDS             28353..30326
                     /locus_tag="J8S10_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HAZ9629939.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30332..30784
                     /gene="rplI"
                     /locus_tag="J8S10_001350"
     CDS             30332..30784
                     /gene="rplI"
                     /locus_tag="J8S10_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HAZ9629940.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            31058..32425
                     /gene="dnaB"
                     /locus_tag="J8S10_001351"
     CDS             31058..32425
                     /gene="dnaB"
                     /locus_tag="J8S10_001351"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HAZ9629941.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            33205..34497
                     /locus_tag="J8S10_001352"
     CDS             33205..34497
                     /locus_tag="J8S10_001352"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HAZ9629942.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
BASE COUNT        10563 a         6737 c         6861 g        10527 t
ORIGIN      
        1 ggagtgtttc ccgattcgtt tttggctgcc gtagcaactt ttatatcata tcagagagac
       61 aagtaattgt caactctttt ttaaaagttt tttcgatttc gtttttcgaa atcttccagc
      121 aactcattta tcataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc
      181 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcat
      241 ttccaacatg tcaacaactt attttttatt atttaataag ttattggtgt tcttttgaac
      301 aaataataat atatcaacat cacatgtgaa agtcaataag aaaatgctta tttatcaaca
      361 tttctagctt acatgatcat tggttagttc tggtcctttt tcgttcgtct ttataactcc
      421 gagagacgta aaatcctttt gttttcagtt taatgttcat gttcttgtct tattcacacc
      481 aactagatgt ctcaccttct aaaattttcc ttaacaaagt gctgctttta tctatttctg
      541 cttttttttg ctagaataat agtaacaata tgactctgga ggatttattt atgaaaattt
      601 tgattgctga cgatgataaa gaaatcgttg aattattaag tatctatgtt cacaatgagg
      661 ggtatgaagc agtaaaggct tatgatggga aagaagcatt atctaaaatc agaacaatcc
      721 ctgatattga attacttatt ttagatatca tgatgcctga gatggatggg atgcaagtag
      781 tgaaagagct acgaaaagaa tcccaaatac caatcattat gctgacagca aaaactactg
      841 atatggataa gatcaaagga ctggtcgctg gtgcagatga ttatgtgacc aagccattta
      901 atccgttaga agtaatggct agagtaaagt ctttattacg gcgtacaaaa atgcagattg
      961 ccccagatca gcctgatgta ttagaagtaa atgcattaat catcaataaa gactctcatg
     1021 aagttaaaac aatcgatggg aaagaaatcc agttaacagc tttggaattc ggtatcctct
     1081 acttgcttgc tagtcatcct aatcgagtat ttagcgcgga tgaaattttt gagcgtgttt
     1141 ggaaacaaga aagtattgtc tctgctaaaa ctgtcatggt tcacgttagt catttaagag
     1201 ataagattga agaagcaact ggtggtgaaa aagtcattca aaccgtttgg ggagtgggct
     1261 ataaaattga cgcaagatag taaacgagca actgaaaaac gccgtcggat caatttgact
     1321 tcaaaagaaa tcagcgaatt gttagcggaa ggaatcatca cgattatcct tttgcttcta
     1381 ttaaatgttt ctattctggt tgttatcagt tcggtgatca acagttcacc ttctttgacg
     1441 aatgcgattt gggattcaaa gaatattttt gcagaacgat tgaacactga tttgttctgg
     1501 aacggccgga attttattat tccctttttc tttctattag atattggtgt tttgtattgg
     1561 cgcttgattc gaagatatcg ccaaatgcaa ttgcggcata tcatcagcga acttcactac
     1621 atcgcaaacg gaaattatga tcatcgtatc ccttttgaac tgagtggtga cttaagccga
     1681 gtggtaacaa gtatcaatgg attggtggat agtaccgtag cagcgattga agacgaacgt
     1741 aaaatcgaaa aatcaaaaga tgaattgatc acgaatgtca gtcatgatat ccgtacccca
     1801 ctcacgtcca tcattggata cctaggactg atagaagatg gccagtatca ctcagaagaa
     1861 gatcttttaa agtatacgca tactgcttat atcaaagcaa agcagatgaa atctttagtg
     1921 gacgacttat ttgaatacac taaggtacgc cagcctgctg tcccggtgaa tttttctgcc
     1981 tttgacatga tccagttgat cgaacagtta gcagctgatt ttgagttgga agcttctaaa
     2041 aaaaatatcc aaatacttgt tcaatcaaaa gtagactccc ttatcatgga tggcgatacc
     2101 gaaaaacttg tacgtgtctt caataatctt ttgacgaatg cgttgaaata cggaaaagga
     2161 gcaacgaaga tcgtaatcga agtagaacgt atcggttcag aagttgttgc aacagtcaaa
     2221 aataacggag caatgatccc acaacaggca atcgataatc tattcgaccg tttttatcgt
     2281 gtagaagaat ctcgttcaca agcaactgga ggaactggac ttggtttagc aatcgctcaa
     2341 agcattgtgg ctttgcacgg cggatacatt tatgcaaaat cagataagca atggacttct
     2401 ttcatcatgc accttccaat caagaaaaat gaaaaattac ctattgatac acaggaagtt
     2461 attgacgaaa gctgaaatat tcgctattct tattacaatt attagaataa atgaaaaaca
     2521 cagaacccag tacactttat tctttttcag agagctgatg gcaggtgtaa atcagcaaag
     2581 gataatttgg aagttccagt tcgtttacgt gccctttcga aataagaaag gtcggttcaa
     2641 cagccgttat gtgttcaaca agtgcagctg acgctgaact tgggtggtac cgcgaatttc
     2701 agactgattc gtcccaagaa taatgggatg gatcagtctt tttttatttt caaaaaggag
     2761 gaaatcatat gttagatgta aaaatgatgc gacaaaatat tgaagaagta caagaaaaat
     2821 tgatgactcg gggcgtaaaa aaagaaacat tagctgaatt catggaacta gatgaaaatc
     2881 gtcgtaagct actagtcaaa agtgaagaat taaaaaaata tcgaaatgat gtttctgctg
     2941 agatcgccca attgaagcgt gcaaaagaag atgcttctgc taaaatcgct gaaatgaaag
     3001 aagtcggtgg caacatcaaa gcattggata ctgaaattgc tgaagtggat gaaaaattga
     3061 aacaaattgc aactactttg ccaaaccttc cccatgattc tgtgccagtt ggaacagatg
     3121 aagaggacaa tgtagaaatc cgtcgttgga gcgaaccacg tacatttgct tttgaaccaa
     3181 aaccacactg ggaaattgca gaaaatcttg atattttaga ttttgaacgt ggcgcaaaag
     3241 tagccggtag ccgttttgtc tattacaaag gattaggtgc tcgattagaa cgtgctgtct
     3301 acaacttcat gcttgatcag catatttacg aacacggcta tactgaaatg atcactcctt
     3361 atatcgtcaa cagtaaagcg atgtttggta cgggacaatt tccaaaattc aaagaagatg
     3421 ttttccaatt ggagaatact gatctaacat taatcccaac agctgaagta ccattaacta
     3481 actattataa tgatgaaatt ttagatggtg cagatttacc tatttatttc actgcactaa
     3541 gccctgcttt tcgttctgaa gccggaagtg ctggtcggga tacacgagga ctgattcgtc
     3601 ttcaccaatt caataaagta gaaatggtca aattttcgga tgtagagcat tcttacgaag
     3661 aattggaaaa aatgacagct gatgcagaag atatcttgaa aaaattgcat ttgccttatc
     3721 gtgtgatggc cttatcaact ggagacatgg gcttttctgc agctaaaact tatgacttag
     3781 aagtatggat acctgcacaa gatacttatc gtgaaatcag ttcttgttct aactgtgaag
     3841 atttccaagc acgccgcgca atgatccgtt atcgcgataa tgatggaaaa atccactata
     3901 ctcatactct gaatggttca ggacttgcag ttggccgtac agtagctgcc attttggaaa
     3961 actaccaaaa tgaagatggt tctgtcacag ttccagaagc gctcgttcct tatatgggga
     4021 atctgaaagt tattaaataa agaggctgtg aaaaagccgc ttagtttcga gtattaagaa
     4081 aaattttgtg aaaatggctt tccacatttt tgcataaatt ggacttaata ccgagaaact
     4141 ggcttttgaa caccatttat cgagaggttg tgaaatcagc gaattaacct gagtattaga
     4201 gaaaaaaatg gaaaaatagt ccctcatatt ttaccgtttg ttgaactaat accgagggtc
     4261 agctgattga acaccgttta gtggagaggt cgtaagccta ccccccagct cctagttaca
     4321 aggacaaatt caaaaaacag ctcttcatat tttatgaatg ttgtacttgt gattcggagg
     4381 tggcaaggga acactgttta ttcaaaaaga ggctgggaca gaagcgttta actccaagaa
     4441 ataagaagaa attcacgaaa attgcttttc aaatttttgt gaatttcttc ttatttccga
     4501 aggagttgct tctacttccg ccgtttatac gtgtttagag cgtgagacaa aagtgttctt
     4561 tacttttgtc ccacgctctt taatgttttt aagattcaac tgaatagttt ggtgcttctt
     4621 ttgtgatttg tacatcatga gggtgtgatt cttttaatcc actgccgctc atttggataa
     4681 attgcgcttc atcacgtaat tgctgtagat tggctgcccc aacataaccc attcctgaac
     4741 gcaaaccgcc gatcatttgg aaaataatat ctgcaacact tcctttataa gcaacccgac
     4801 cttcgattcc ttctggtact aatttatttg cttcattgac actaccttgg aagtaacggt
     4861 cttttgaacc tttttccatc gcgcctaatg agcccatacc tcggtatgtt ttgaatcgac
     4921 gtccttggaa gatttcgaat tcacctggtg attcatctgt ccctgccaac atacttccta
     4981 gcatcactgc atgtccgccg gcagctaatg ctttgacgat gtcaccagaa tatttgatcc
     5041 ctccgtctgc aataatcgct ttgccatatt gacgagcaac tgatgctgca tcataaatag
     5101 ctgtgagctg aggtacacct acaccggcta ccacacgtgt cgtacaaatc gatcctggtc
     5161 cgataccaac ttttacgaca tctacacctg catcatataa agcttttgtc gcttcagccg
     5221 tcgcaacgtt tcctgcaatc aatgttgcat ctgcaaaagt tgaacggatt tcttgaattt
     5281 ttcggatcac acctgcacta tgtccatgag ctgtatcgat gatgattgca tctgcccctg
     5341 cttctaataa agcattcgca cgctcaaatg tatcgcttgt tacaccaacg gctgctgcta
     5401 caagcaatcg accatgttca tcttttgctg catttggaaa ttcgatcact ttctcgatgt
     5461 ctttgatcgt gatcaatccg cttaaacgac cttcgttatc tacgattggt aatttttcga
     5521 ttttatgttt ttgcaaaatc ttttctgcat cttttagaga ggtacctact ggggcagtca
     5581 ctaagttgtc ttttgtcatc acatcagcaa tcggcatgtg ataatctgtt acaaaacgca
     5641 tgtcgcggtt tgtaattatc cctaccaatt ttctgttttc aagtgtttca acgattggca
     5701 caccactgat acgatatttg ctcatcaatt cttctgcgtc tgctacaaga tgctgcggcg
     5761 ttaagaagaa cggatcaatg attacgccac tttcagaacg tttgactttt cttacttcat
     5821 ccgcttgctg gctgatcgtc atgtttttat ggatcacacc tagtccgcct tgtcttgcca
     5881 tagcaatggc catcttgctg tcggtaacag tatccatact tgcactgatg attggaatat
     5941 tcaacttaat atttttagct aattgtacgc tcatatccac ttcgtttggt aacacgtgac
     6001 tttctgctgg tatcaataag acatcatcaa aagtaaatcc ttttttcgtg aactttgttt
     6061 cccagttgga catttttagt accactcctc taatttagtt tatctattaa aataattgat
     6121 tttttcattt aagtcaatga tctacttgga atcaagttag ctttctcata gaataccaat
     6181 ataaagcgtt tacatctgtg tgtattaaaa gagattgtaa aaaagctgtc ctgcatcaag
     6241 taataagaac agccaatcaa aaacagcttc tcatgttttt gaattggttg ggtttattac
     6301 cgcagatgca aacttttgaa caccgtttag tggagaggct gtgaaaaagc tgcttagttt
     6361 cgagtagtaa gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa attggactta
     6421 ataccgagaa actggctttt gaacaccgtt tatcgtaaaa agggactgtg acaagacttt
     6481 tgtcacagtc ccttactatt atttaactat ggataaacaa aatgaggttc tttactaccc
     6541 ctagatatct agcaaaatag ctgatctttt tgctagttta tcttcttggg acggataaac
     6601 ttccaataat cccgtatttt ttcttcaagt agtaacggat tgctaaagca gttgccccga
     6661 taatgataac tactactgga tctaatactg gattgataac tggtggcaat agtgttgtcg
     6721 cagaaaacag tacgacccaa agaagtgtcg ttccacctag gataagcaat gtcttaccca
     6781 ttcctggttt cttgcttcga tctgctccgg gatattcata ttgatagatg tatttgtaca
     6841 tcatataaaa gacccagcca ccgattgcag aacctagaac gagtgtagaa aagccataag
     6901 ctggcgttgt tccacgtgaa aacaatccgg taatcgcaat catgatactt aatagaccaa
     6961 gcaacagcaa cgtattatct aaccacatca ataaaggggt ggatgaattt tttacttctg
     7021 ctggcttatt gatgattgct tccgttcttt cagagactgt cccaaacaat tgacgggctg
     7081 ttcttccgcc tttttgttct gcaactaaag taggcagaat gtcatgaagg gcttttactt
     7141 tttcttcttc agacaaattc gctgcttcta aagatttttt caaatcaaaa atgtactgtt
     7201 gatttctttt ggttaatttt gtttctaaac tattgttttc ttttacgatt gctcgtaatt
     7261 gttctggttc cattatctaa tagtcctcct tagccgttcc ttttctcaac ggtcgtcaca
     7321 aaagacattc taccatattc tacagctagt ttgatagccc ttttacacat taaagcggaa
     7381 taacattacg tcgccgtctt gtacgacata atcttttcct tctaatcgaa cacgtccagc
     7441 ttcttttgct gcatgcatgt ttccgtaatg atccaagtct tcaaaagaga cagtttctgc
     7501 acggataaat ccgcgttcga aatctgaatg gatgattcct gctgcttgtg gtgctttgat
     7561 tccttttttg aatgtccaag cacgtacttc ttgttcccca gcagtaaagt aagtagctaa
     7621 gcctaacaaa tcataagcag cacggatcaa ctgatccaaa cctgattctt cgattcctaa
     7681 agcttctaaa aattccgctt tgtcttcttc atctaattct gcgatttctt cttctgcacg
     7741 agcactgacc acgatcactt ctgcattttc ttctgcagca aagttgcgca cttcttgtac
     7801 ataatgattc gcgtctgcat ctgctacgtc atcttctgag acattggcta cataaagaat
     7861 tggttttgtc gtcaataaaa atagtgattt aacgattttt tgttcttctt cagtaaattc
     7921 gatcgttcgg gcagattttc cttcttccag tacaggtttg attttatcca gtacagctag
     7981 ttctgccact gcatctttat ctttggtttt agcaactttt gctacacgag tatagcgttt
     8041 gttgatagat tctaagtctg ctaacactag ttccaagttg atcgtatcaa tatcttctag
     8101 tggatcaaca cgtccttcta cgtgagtaat attatcatca tcaaaacagc gaacaacgtg
     8161 acaaatagcg tctacttggc ggatatggct taagaattga tttcccaaac cttctccttt
     8221 acttgcgcct tttacgattc cagcaatatc tgtaaattca aaagtcgtcg gaacagtttt
     8281 tttcggatgt acaagttctg ttaagcgttg caaacgccag tcaggtactt ctaccatccc
     8341 tacgttgggg tcgatcgtcg caaagggata gtttgctgct tctgctcctg cttttgtgat
     8401 cgcattaaac aaagttgatt ttcctacgtt gggcaaccca acaattccag cagtcaatgc
     8461 cataaattta ttcactcttt ctctgcattt ttttcaatta ctttttttaa tttcttttca
     8521 aaatctcgac gggtcatcat gacgatatgt ccgcaattca tacatctgat tttgatatct
     8581 gcgcccattc gaatgacttc ccagcgattc gtctggcaag cgtgaggttt tttcatttca
     8641 acgatatcgt gcaagtcgta cataaaaata gcctcctttt tgtttattct tcatcaaatt
     8701 gaatattcaa gatatcaaga attcgagtca aatctttttg agaaagatat tcaatctcga
     8761 tcttaccttt cccatttttt tcttggatag ctacacttgt accaaattta tccatcaaac
     8821 gatcttcgct ttctcggata taatatggtt tttcctttgc tagccttggg atttttttct
     8881 tttcttttcc atcattttga tttaactcag aaacaagctg ttccagttgg cggacagtta
     8941 aattttcagt tactgcacga ttggctaatt tcaagatcaa tgttttattt tttaaaccta
     9001 acagcgtacg ggcttgtccc atagataaac gctgatcttg taccatttcc ttgacaagat
     9061 ccggtaaaga aagcaagcgc aaataattgg cgatataagg tctgctcttt cctaaacgac
     9121 tagctacttc tgcttgtgtt agtttcaggt ttttcatcag catctcatat gcttctgctt
     9181 cttctaacgg attcagatct tctcgctgca agttttccag cactgctact tgcatcatcg
     9241 cttcttcgtc aaagtctcta acgatagcag ggatcgtttc tttttcagct agtttggacg
     9301 ctcgaaaacg tcgctcccct gcaataatct catatccttt tactgcggaa cggcgtacga
     9361 tgatgggttg aaagacacct gattgttcaa tagaattagc tagttcctgc aaagatactt
     9421 cttcaaatgt tttacggggc tgatacggat ttggtcgcag ctcattcaat ggtagctgga
     9481 caacggtatc atcttttaca tccaccgtct ctaagttttc taaatcttga aacagtgcat
     9541 cgattcctcg gcctaatcct ttacttttct tcacgactta ccacttcctt tgccaatgct
     9601 tggtagactt cagctcctcg agaacgtgga tcgtagtcga tgatcggttt tccatgacta
     9661 ggtgcttctg ataaacgaat atttcttgga atgatcgttt cgtaaacttt ttcgcggaag
     9721 tatttacgta cttcttctac gacttcattt cccagatttg ttcgtgcatc atacattgtc
     9781 agtaagactc cctcgatctc taattctgga ttaaagtgtt tttggactaa acgaaccgta
     9841 ttcagtaatt ggcttaatcc ttccaatgcg taatactcac actgaacagg tatcaaaatc
     9901 gaatcacttg ctgtaaatga attgattgtc agatggccaa gagaaggcgg gcaatcgatc
     9961 aaaatataat catactgact gcttacttct gctaaagatc cttttaatct tgattctctt
    10021 gccatcattg acgtcaattc gatctctgct cctgctaatt ggagagtcgc aggcacaata
    10081 ctcaaatttt cgtgttcagt gatcaaagtt gcctcatcaa ttggcaattc attgactaga
    10141 acatcataga tgtctcttgt cacatcaggt tttctgatcc cgacaccact ggtagcattt
    10201 ccttgtgcat ccatatccac tagcaatact tttttgccaa ggctagcaag acaagcacct
    10261 agattcaccg tcgtcgttgt tttgccgacg ccaccttttt ggttcgcaac agatattatt
    10321 tgtgccatct cttctcctcc tatttgattg gctgcttatt aggcagtccg ggctttcttg
    10381 ggtatttctt tggggttggt ttcttttttt gaataacgat gatatgccgt tgatcagaga
    10441 cattcggcaa ggtaaccgcc tcttctttga ggaatttacc acctaataaa gcaatcgctt
    10501 gttttgcttc tgtcaattcc tcttcacttt ttgctgcttt caatgcataa aaatagcctt
    10561 cttgtttagc caagggcaaa cacaattccg ctaacacatt caaacgagca accgcacgag
    10621 cagtgacaag gtcaaatgat gcacgaaagt gaggattttg cccaaatgtt tctgcccggt
    10681 catgatataa ggaagcatcg attcctaata atcgggttaa ctcagataag aaggttattc
    10741 gtttattcag agaatcaacg atcgttatct gcagttctgg aaaggcaatt tttaaaggta
    10801 tgctaggaaa ccctgccccc gaaccaacat cgcataaaga taaaggttgc gtaaagtcta
    10861 cttcaaatgc taatgtaagt gaatcgtaaa aatgcttcag atatacgtct ttttcatccg
    10921 taatagctgt aaggttcatc ttttcgttcc attcgactaa tgtccgataa taaatagcga
    10981 attgattcat ttgatgatcg gtaagctcta tccctttttc tgccaaggat tggcgaaatt
    11041 cttctggtat cataaatatt cctttcattg tgaaacagca attgtttcac agattctctc
    11101 cctactttaa cgcaaaatct ctagacatgc aatccttcca tatggattct taaaaatttg
    11161 aaaagtaaga aaagccgata gactttttct ttctagtatg actcataaaa tatacacaga
    11221 agagagaact agctttgagc aatttctgca aaaactagtt ctctcttcta tttattatta
    11281 cgtattacgc tggttcactg actttcgcaa tcttcccttg ttcgatatag accattagga
    11341 tacttaggtc tgcagggttt acgccactga ttcggctagc ttgggcaatt gtttctggtt
    11401 ggattttctg caatttttgt tttgcttctg ttgctaatcc gttgattgct gcgtagtcga
    11461 tgttttctgg aatctttttc gcttccatgc gttttaattt ttctactttt tccatggctt
    11521 ttttgatgta gccttcatat ttgatttgga tttctacttg ttcgatttct tttcgtgtca
    11581 attcttcatt ttctggaata aaccgtagaa gttctgcata agtaatctca ggacgtctta
    11641 aaaagtcgct tgctagtaca ccatctttta atggtgccgc attaatcgtt gctaaaaagt
    11701 cttggacttc ttctgttggt ttgattcgta cattcatcaa acgtttgatt tcttgttcaa
    11761 ctgcttcttt tttcttcaaa taattcttgt attgatcttc ttttactaag cctacacggt
    11821 gacccatttc tgttaatcgc aaatctgcat tatcatgacg taaaagcaga cggtattcag
    11881 cacgtgaagt cagcaaacga taaggttcgt tcgttccttt tgttaccaaa tcatcgatca
    11941 tgacaccgat gtaaccgtca cttcgtttga tcactaaagg ttcttttccc tgaactttca
    12001 aagctgcatt gataccggca atcagccctt gtccagccgc ttcttcataa ccgcttgtac
    12061 catttgtttg tccagctgta taaagatttt caacgacttt agtttctaat gtcggacgga
    12121 gctggtgtgg ctctactacg tcatattcga tagcatatcc tgtacgcatc atttctactt
    12181 tttctaatcc agcaatagaa tgaagcatgt tgacttgaac atcctctggt aaagaagtag
    12241 ataaaccttg aacatagact tcttccgtat ttaagccttc tggttccaaa aataattgat
    12301 gacgtggttt gtctgcaaaa cgcacgatct tatcttcgat ggatggacaa tagcgagcgc
    12361 ctaccccttc aacgatccct gtaaacattg gggcacgatg taagttgtct cgaataattt
    12421 ggtgagtcgt ctcacctgta taggtcagcc agcaagattc ctgatctagt ttataggcac
    12481 tatctggtgt gctgaagcta aaatgattcg gctctttgtc accaggctgc tcttctgtaa
    12541 cagaatagtc gatcgtactt gattttactc gaggcggtgt tcctgttttg aaccgttcga
    12601 tagcaaagcc aagttctttt agatgattcg ctagtccaat agaaggttga gagttattcg
    12661 gacctgatga atatttcaat tcaccgataa tgatttctcc gcgaagtgct gttccggctg
    12721 taataacaac tgctttggcc cggtagctcg ctcctgtgga cgtcactact ccatgacaaa
    12781 caccatcttc gacgatcagt tcttcgacga ttccttgtct tagcgtcaaa tttggttctt
    12841 tttcgatcgt atgtttcatt tctgttgaat aagcatgttt gtctgcttgt gctcgcaatg
    12901 ctcggacagc tgggcctttt cctgtgttca acatacgcat ttggatatag gttttatcga
    12961 tattcttacc catttctccg cctaacgcat cgatttctcg aacgacaacg cctttagctg
    13021 gtccgcctac agaaggatta catggcatga atgctaccat gtccaaattt attgtcagta
    13081 ataatgtttt tgatcccata cgtgcagcag caagtgcagc ttctgaaccg gcgtgtcctg
    13141 cgccaacaac gatcacgtca tacgcatctg cttcataatg ttccaatcgt ttgttcctcc
    13201 ttttattttc ctaaacaaaa ttgactgaat aattgagtga ttagctcatc ttgtacactg
    13261 tcgccgacaa cttctcctag atagtcccag caacgcgtca tatctatttg aacgagatcc
    13321 acaggcattc ctgaatcaat acctgcaatg acttcttcaa gtgagaggga agctttttct
    13381 aacaacgcga tatggcgggt attagaaaca taagtagcgt ctctttctcc tgtttctccg
    13441 ctgaagaata aatcagaaat agctgattcc aaacgatcta gtccgtcgtt tttagctacg
    13501 gaaattgaaa aaactggttc attttcgatc aatttcttca atttttcttg ttccagctgt
    13561 gctggcaaat ctgttttatt tagaagaatg atccgtttca atccacttgt cgcttccaat
    13621 aattgttcat cttctgctgt cagtggttcg ctttggttta gaacaagtaa gatcaagtct
    13681 gcttctgcta atgcttttcg gcttctttcg accccgatcc gttccaccac atcttctgtt
    13741 tcccgaattc cagctgtatc gattagcttg agcggtaccc cccgaacatt gacatactct
    13801 tcgattacat ctcgagtcgt tcctgcaata tccgtaacga ttgctttttc ttctcttaac
    13861 aaatggttta acaaacttga tttgccgaca tttggccggc cgatgattgc cgtacttaac
    13921 ccttcccgca gaaccttccc ttgcttggat gtagcaagta gcgcttggat tctttgttgg
    13981 atcatctgcg ctttttcaag caataacttc gtagtcaatt cttcgacatc atcatattct
    14041 ggataatcaa tatttacttc tacttgtgct aatgtctcta aaatctcttg tctcaatgag
    14101 cggatcaaag cagacagatt gccgtctaac tgattaagag ctagtcccat tgctttgtct
    14161 gtttttgccc gaatcaaatc catcacagct tctgcctgtg aaaggtcaac acgaccattc
    14221 aagaatgctc gttttgtgaa ttcgcctggc tcagctaatc ttgcaccttc tcttaacaat
    14281 agctgcaaaa tttgattgac tacaacgatc ccaccgtgac aattgatttc tactacatct
    14341 tcccgcgtaa atgtctttgg tgctctcatc acggagacca tgacttcatc gacaagctga
    14401 ttgctcttgg gatcaacgat atgtccataa tggatcgtat gacttggtac ttctgataat
    14461 cgtttgtttc cagattgata aactttatct gctagttgca cagcttgatc gccacttaaa
    14521 cgaacgatac tgattgcacc ttctccaggt ggggtagaaa ttgccgcaat cgtatcaaat
    14581 tctaaagtaa tttcagccat tttttcactt cctttttcat tttgcgcaca aaaaaagtgc
    14641 ccactccacc ctttatgcac aataaacggt gaacttcgca ctttgactgc ttgttcttga
    14701 ttaaattctg gtcatagatt atcacacttg ctataaggaa tcaagtgttt aaaacaatta
    14761 gatgaagttg agcctgttct gcttccatta ccttatattt aattgtcctt ggatgtctct
    14821 ttgcgttctt tggtttattc gaagagaaga tactgtataa acaaggcttt atctttctta
    14881 aaaaaaacgg tacactaaat ggtagcgcta tctaaactat acacttttga aaggagaaaa
    14941 tatgtgagcc cgttcagatc tgctgcattg gaagaagaaa gtgaccctcg gatcaacgat
    15001 gtcgttttat ctacagggaa tatcaaccag aaatatatcg tccgcgatat cgtttttgtt
    15061 gtggaatgct tagaagctga tttgtttgac ccatcttttc ccaaagatga ccttttctta
    15121 acaacgaaga ggaaattaaa gacgaaggta cttgaatatg gtgcgaatgc agtaatcaac
    15181 tgtcattttg agtatcagca aaaaaaacgc gacggaaagt attttctgga actttttgct
    15241 tatggaacag tgatccaatt tatccaaaca acgattggtt aaatgaaaca gacaaaaaaa
    15301 gcggatcaaa actgaagaca gtttcgatcc gcttttttct atcaaagtta gtgactactt
    15361 catcgtatac tctgataaga atgatttcta gtaaaatata cttggtttga aaaactttgt
    15421 caacgtgatt tattcaaaaa gtaatggaat caataatatt ttttagcagg ttctactact
    15481 aaataacgat aaggttcctc accttccgaa tgtgttttta catgttcatc tttgcttaat
    15541 gcagcatgga tttgtttacg ttcaaatgca ggcattggtt ctaagaaaac aggctgccct
    15601 gtccgtttta ctttttcagc cgtgcgatca gctaaacgct gaatgatctc ttggcgcttt
    15661 tcacggtaat tgcctacatt gactactaca gacagcttat ttcttgctaa acgatggatg
    15721 aagacttgtg ccagatattg caatgcattc agtgtttttc catgtttccc aatcagtatg
    15781 ccttgctttt gtgtttctaa atggaaaaca accatattat ttgattctct ttccattttg
    15841 acaagagctg gagcatcaag ctgttttgaa atttcagtaa gataaactgc caattccgtt
    15901 aaagctgctt catcacctag ctcacttact tcttctgttt tttcttcaag aatcgtttcg
    15961 ttgactacct cgatctcagc tgttggttct tcttccaaaa tttcttctac agtctgttct
    16021 actgtttcag aaactttttc gctgatactt ggctggatcg aaagccgtgc attctttcga
    16081 cccattccta ggaaaccttt ttttccttct tccagtattt cgatttcgac ttggtctttg
    16141 gccaaaccca aatcagccag acctagttgg acagcttcgt ctattgttgc agcttcataa
    16201 atcggcatta gcattacctc ccctattatt tccgtttttt cttaggattc attgctttct
    16261 taagagcacg ttctctttcg cggattctcc gtgcttcttc ttcacgctct tttcgaattt
    16321 tgaaagggtt gttgatcagc agcgtttgta caacttggaa ggcattggaa actacccagt
    16381 ataatgaaag accgctggct aaattgacac ccatcactaa aatcattaca ggcatcacga
    16441 aattcatgat cttcattgat gcattcgatt caatttgact catgctagat aaatacgtac
    16501 ttgcaaaagt aaagattgct gctaaaatcg gcaaaataaa tgttggatcc gcgttcccta
    16561 agttcaacca taagaaatgc ccttgtttca actctggtac acgtgaaata gattgccata
    16621 acgccatcaa gattggcatt tgtactaata aaggaagaca accagcatat ggattgacgc
    16681 cattttctgc atataaacgc tgctgctctt ctcttaactt actttgtgtt tccggatctc
    16741 ttgaactata ttgttgctgc agtgctttta atttcggttg taattcttgc gttttacgca
    16801 tgctctttgt ttggaaatgc atcaacggca ataggatcac gcggatgatc agtgtaaata
    16861 aaatgatccc tatccctgca ttaccaaatg acaacgcctt gatcgcctca gcaaagtaat
    16921 aaacaatata acgatcccaa attcctgtac tctgtgcgct gacttcccca gttccgcaac
    16981 cggataagac gatgaccaaa ctaacgatac cggccatcaa aagtaaacgt ttgtatttct
    17041 tcacttactc ttttcctctc tgtcgattat ttttgcaagt tttaagacgt ggactaaatt
    17101 ggagcgaacc tcatcataag tcaacccctt cacacttggt ctagcaatca caataaaatc
    17161 caactccgga tcaatttctt cttttataga ataaactgct gctcggattt ttcgtttgac
    17221 ttcattgcgg tttaccgcgt tgccgacctt ttttcctaca gataaaccaa ctcgaaaatg
    17281 aggctgtccc ggtttttcca aacggtaaac gacgaatttg cggttagcaa aagaatctcc
    17341 cgtatggaac acggcttgaa actctcgttc tttttttact cgatacgctt ttctcattag
    17401 ttttctttcc ttttctatct ctcacttacg ctcataatca taccataatt acgattgtcc
    17461 tttcatcatt tccctaaaaa agagtataaa aaaaaccact gaaaccccag tggcctaagc
    17521 tgaaagaact tttcttcctt tgcgacgacg gctagctaac acacgacgtc catttttagt
    17581 actcatacgt ttacggaatc cgtgaacttt ttgacgttta cgtttatttg gttggtatgt
    17641 tcttttcata tattccacct ccaaaatgtt cttatctatt ttataaacac agacatactt
    17701 tgatagtata acgacaaagt agtgattttg tcaatataaa atagaagatc gattgttaaa
    17761 acttatccac aagattattt ttttctatgg gagtcctatg tggaaaaagt tatgcacagg
    17821 gattatccac agataataaa tggctggttt tacacagaaa acacacgtgt aaaaaaagta
    17881 atccacaatc aggtgatttc ctgtgtattc cgtctcctaa ctattggtat atctatattt
    17941 tttatccaca gatgcaagag gaaatctatt gatttttacg agttttccac ctgtgcatta
    18001 gtggtgtgga aaactttttt ttgacaactg tgtttttctc ttttttcttt ttgtcgattg
    18061 tgtggataat tgtaattaaa aaattttttt cttcggtttc tgtggaaaac tattgaaaaa
    18121 aatgctaaat tagtactagt tattcacttt ttaatgaagg aggaggcctt atatggtatc
    18181 cctcgatgct ttatggaatg aattaaaagc aacataccaa aaggatttat cgcctgctag
    18241 ctataataca tggatcgaaa cagcgaaccc tcgaaccctt gatcaaaacc agctcgttgt
    18301 tgaggttcct agcaagattc ataaagaata ttgggaaaaa aacctggcga caaaaatcgt
    18361 tgaagtcggt tatatgttat caggaaatga gattatccct cgctttatta ctggcgaaga
    18421 agcagagcaa gaagaagtta tagaagaaaa aaatccaaaa gttgtggcac ctagtccgct
    18481 aaaaaaagcc atgctgaacc ctaaatatac ctttgatacg tttgtcattg gtaaaggaaa
    18541 ccagatggct catgcagcag cgctcgttgt agcagaagat ccaggttcta tttataaccc
    18601 gctcttcttt tatggaggcg tgggacttgg taagactcac ttgatgcatg caattggtca
    18661 tcaaatgctg caaagtcagc ctaatgccaa agtaaaatat gtaagcagtg aaacttttgc
    18721 taatgatttc atcaattcga tccaaaacaa aacagcagaa gagttccgtc aagaatatcg
    18781 aaatgttgat ttactgctag tggatgacat tcaatttttt gcagaaaaag aagctacgca
    18841 agaagagttt ttccatactt tcaatgcctt gtacaatgaa gggaaacaaa tcgtactaac
    18901 cagtgatcgg ttgccaaacg agattccgaa actgcaagaa cgcctcgttt ctcgctttgc
    18961 atgggggctg tctgttgata ttacaccgcc ggatcttgaa acaagaacag cgattttacg
    19021 taaaaaagcg gcggctgaac gtctagagat cccagatgac acactaagct acatcgcagg
    19081 acaaattgat tctaacattc gtgaattaga aggtgcgctt gttcgagtgc aagcttttgc
    19141 tgcgatgaat agtgaagata tttcgactag tctagctgca gacgcactga aaacgttaaa
    19201 atcaggaaaa ggacatcctc aattgtcaat cctgcagatc caagaagaag tggcaaagta
    19261 ttatcacatc caattgaaag atatcaaagg aaagaaacgc gtcaaatcta ttgttgttcc
    19321 tagacaaatc gctatgtatt tggcacgtga gctcacagat aattctttac cgaaaatcgg
    19381 agctgaattc ggtggcaagg atcatacaac ggttatccat gctcatgaaa aaatccagca
    19441 gctgatggat tctagtgtca gtatgcaaaa tgaagtatca gaaatcaaaa actttttact
    19501 aaattaattt gtcgattcta tcaactgaaa atagcatgtg gataaaagaa aaaaacgttc
    19561 aaaagttatg cacacttttt ccacagctgt tttttcgttt ctctcttacg ttttttgagt
    19621 tttccacaga atcaacatgc cctattactt ttattattct ttttaactaa taataaataa
    19681 acaaacattc aaaggagata catcatgaaa gttactttaa accgagctag ctttatgcag
    19741 gaattgcaaa ctgttcaacg agctatttca agcaaaacca cgatccctat tttgacaggt
    19801 gtaaaaatca cactgacaca agaaggtttg actttgacgg ggagcaacgc tgatatatca
    19861 attgaaactt ttttgtctgt tgaaaacgaa aaagcaaata tgcaaatcga atctactggt
    19921 tccattgttt tacaagcacg tttctttagc gaaatcattc ggagacttcc tgaagaaaca
    19981 tttactttag aagttttaga aaataaacaa gtagcgatta cttctggaaa agcgaatttt
    20041 atcgtaaatg gattagatgc agataactat cctcatcttc ctgttgtcga aagccataac
    20101 cagatgaaat tacctgtaca cgtattgact aaactaatca acgaaacagt ttttgctgtc
    20161 tcacaacatg agagtcgtcc aatcttgaca ggtgtgcatt tcattttatc tgataattct
    20221 ttattggctg tagctactga ttctcaccgt ctaagtcaac gcgtgattcc agtagaacaa
    20281 gcggctgatc attttgatat tgttattcct ggaaaaagtt tgatcgaatt atctcgctca
    20341 ttaacaaatg aagaagaaat cgtcgaaatc agcattatgg aaaaccaagt gttgttcaaa
    20401 acagaaacga tgtatttcta ttcccgtttg ctagaaggaa actatcctga taccaatcgt
    20461 ttgattcctt caagttttaa tacagaggtt gaattttctg ttcctagctt tttagcggcg
    20521 atcgaacggg cttctttact ttctcatgaa ggccgtaaca acatcgttcg tttatctatt
    20581 cgtccagatg cggttgtttt atacggaaat tcgccagaaa tcgggaaagt agaagaaagc
    20641 ttgagttata cagcaagcag tggcgatcca ttagatattt ctttcaatcc ggattatatg
    20701 aaagcagcgt tgcgtgcatt tggagatatg agcatcaaag tgaaatttat ctctgctatt
    20761 cgtccattta cattggaacc aacggaagat ggcgttcaat ttattcagct gattactcct
    20821 gtacgtacaa attaacaatg attttcattg ttcttgaaaa tttaattgaa aagaaataga
    20881 aaaaataaaa ttttaaacag aaggccctaa aatctctttt aaggctttct gtttattttt
    20941 gtttaaatca ccttttttag attaaatcgt cttatatgga aaaatatatg gataaatttg
    21001 ttttattgcg aaaaaaaagg tataatagag tatactttta ataatgaaaa tgagggatgg
    21061 gcattgaaac aacaagtcat tctaaatacg gaattcatga cgttgggcca aatgttgaaa
    21121 gaagtcacag ttatcggtag tggcggacaa gcaaaatggt atttggcaga aaacactgtg
    21181 ttagtcgatg gcgaaccaga aaatcgtcgt ggacgcaaac tttatcccgg catgatggtt
    21241 gaagttccag aagtaggaac tttttttatg gtaaaaaaag gaaacgacga taatgaggct
    21301 gaataagctg tatttaaaaa attatcgaaa ttacgaagag ctgaacatcg aattttccaa
    21361 gaacctcgtc atctttttag gagaaaatgc gcaaggaaaa acgaatcttt tggaaagtat
    21421 ctacgtatta gctatgacgc gaagtcatcg gacaagtagt gagcaggaat tgattggctg
    21481 gactgacgat caggcgatga ttcaaggaga gatcacaaaa ggttcatcca ctcttccatt
    21541 agaaatctta ttatctaaaa aaggccgaaa aaccaagatc aaccatatcg aacaaaaaaa
    21601 gttaagtact tacgtgggac aaatgaatgt cattttattt gcaccagaag atctttcttt
    21661 agtaaaaggc agcccgcaga tcaggcggaa gtttttagat atggaattag gccagatcaa
    21721 tccaatctat ctttatgatc ttgtccaata ccaagcaatt ttgaaacaaa gaaaccagta
    21781 tttaaagcaa ttgaatgaaa aaaaacaaac tgatttgctt tatttggata ttttgtccga
    21841 acaactagca gcgtttggca gcaaagtatt gaaagcaaga gcacagttcg tcaagcgatt
    21901 ggagttttgg gctaattctt tgcatcagca aatcacccat caaaaagagc agctggaaat
    21961 cgagtatctc accgcagtcg attctttaga aacacatacg caagagcaaa tccaagaaca
    22021 atttctcgca cttttgaacc aaaataaaaa gaaagacctt tttcggggaa caacgacagt
    22081 tggtcctcat cgtgacgatc tttccttttt tattaatcag aaaaatgtgc agacttatgg
    22141 atcgcaagga cagcaaagaa caactgcact aagtgtcaaa ttagcagaaa tcgatttgat
    22201 taaagaagag acgggggaat atccaatcct tttgttagat gatgtgatga gcgagctgga
    22261 tgatagtcgt caactccatc tgctagaaac aatcgaagga aaagttcaaa cgttcttaac
    22321 aacaacgaca cttgaccatg taaaaaataa aatgactgtt gaacctgaga ttttttatgt
    22381 tcaacaaggg aaactaaaag gagaagaaac tgaatgacag aagaaagaag tttagtagaa
    22441 cgcgctaaag agtatgatgc cagtcagatt caagtacttg aaggacttga agccgttcgt
    22501 aaacgacctg gcatgtatat cggttcgact agttctgagg gtctgcatca ccttgtttgg
    22561 gaaattgtcg ataattcgat cgatgaagta ttagcaggtt ttgcaacgaa aatccatgtg
    22621 attattgaaa aagacaacag tatcaccgtt attgacgacg gtcgggggat acctgtagat
    22681 atccaggcaa aaactggacg tcctgcagtt gaaacggtct ttactgtttt acatgctgga
    22741 ggaaaattcg gcggtggtgg gtacaaagtt tctggtggac ttcacggagt aggatcttct
    22801 gttgttaacg cgctttctac acagcttgat gtcaaagtat acaaagaagg aaatgtgtac
    22861 tatcaagaat atcgtcgtgg agctgtagtg gacgacttaa agattatcga acaaacggat
    22921 cgccatggaa caacggttca ctttacgcca gaccctgaaa tttttacaga gacaactgag
    22981 tttgattttt caaaattggc tacccggatc cgtgaacttg ctttcttgaa ccgcgggatg
    23041 cgtatatcga ttgaagacaa acgagaagaa gaaccagtca tcaatgaata ccattatgac
    23101 ggcgggatta aaagttatgt cgaatacttg aatgcaaaca aaaccgtgat ttttccagaa
    23161 cctgtatatt tggaaggtga acagcaagat atcgcagttg aagtctctat gcaatataca
    23221 gacggctacc attccaatat catgagtttt gccaacaata tccatacgta tgaaggcgga
    23281 acacatgaat caggattcaa gactgcttta actcgtgtga taaatgatta tgcccgaaaa
    23341 caaaagctga tgaaagaaaa tgacgacaac ttgaccggtg aagacgtgcg agaaggattg
    23401 acagctgtta tttctatcaa gcatcctgac cctcaattcg aaggacaaac aaaaacaaaa
    23461 ttgggcaatt ccgaagtacg gacagtcact gatcggttat ttagcgaaca tttcatgaaa
    23521 ttcttgctgg aaaacccaag tgtgggccgt caaattgttg aaaaaggatt actagcttcc
    23581 agagctcgtc tagcagcgaa acgtgcgcgt gaagtaacga gacgtaaagg tgctttagag
    23641 attagtaatc tgccaggaaa attagcggac tgctctagca acgatcctga aaaatgcgaa
    23701 ttgttcatcg tcgaaggaga ttcggccggc ggatcagcta agcaaggtcg taatcgagag
    23761 tttcaagcca tcttgcctat tcgtgggaaa atcttgaatg ttgaaaaagc aagcatggac
    23821 aagatcttgg caaatgaaga gatccggtct ttatttactg ctatgggtac agggtttgga
    23881 gaagattttg atgtatcgaa agctcgctac cacaaattag ttatcatgac tgatgccgat
    23941 gtcgacggcg cgcatatccg tacattgctg ctgactcttt tttatcgtta catgcgtcct
    24001 attgttgaag ctggatacgt ctatattgct cagccacctt tatacggggt aaaacaaggg
    24061 aagaatatta cgtatgtaca accaggaaaa aatgcagaag aagagttgaa acaagtcgtt
    24121 gcttcacttc ctgcctcacc aaaaccaagc gttcagcgtt ataaaggact tggagaaatg
    24181 gatgatcatc aactatggga aacaactatg gacccaagca atcggatgat ggcccgcgtc
    24241 agtgtggacg atgctattgc agcagatcag atatttgaaa tgttgatggg ggatcgagta
    24301 gaaccccgtc gtgcattcat cgaggaaaat gcacactatg tgaagaactt agatatttaa
    24361 tcatgaagga ggaaaaagaa tgagtgaaga aatcagagaa aacatccatg atgtcaatct
    24421 aaccagcgaa atgaaagact ccttcatcga ttatgcgatg agtgttattg tcgcacgtgc
    24481 acttcctgat gtcagagatg gtctgaaacc cgttcatcgc cgtattttat acggcatgaa
    24541 cgaattaggt gtaacaccgg ataaagccca taaaaaatct gccagaatcg tcggagatgt
    24601 catgggtaaa taccatcctc atggagacta tgcgatctat gagtcaatgg tacggatggc
    24661 acagccattc agctaccgtt atatgctagt ggatggtcat ggaaactttg gttctgttga
    24721 cggtgacggt gccgccgcta tgcgttatac cgaagcacgg atgagcaaaa tcgctacaga
    24781 aatgctgcgt gatatcaata agaacactgt tgatttccaa agcaactatg atgatacaga
    24841 aaaagaacca gttgtactac ctgctcgctt cccgaatctt ttagtgaacg gaacaacggg
    24901 gatcgccgta ggtatggcca cgaatatccc acctcataac ttgtctgagg tagtagcggc
    24961 tatcgatttg ctgatggata atcctgatgt gacgaccaat gaattgatgg aagtattacc
    25021 tggaccagat tttccaacag gtggtttggt tatgggaaaa tcaggaatcc gaagagcgta
    25081 tgaaacaggt aagggttcta ttaccgtacg tgcaaaagtt gagattactg agatgccaaa
    25141 tggtaaagaa cggatcatcg tgacagaatt gccttatatg gtcaataaag caaaattgat
    25201 cgaacggatt tctgaactgc acagagacaa gcgtatcgaa gggatcacag atttgcggga
    25261 cgaatcttcc cgtgaaggta tgcggatcgt cattgacatc cgtcgtgacg ccagcgcatc
    25321 tgttatcttg aataacttat ataaattgac atccttgcaa aattcatttg gattcaatat
    25381 gttggcgatc gaaaaaggtg tgccgaaagt tttgagcttg aaacaaattc ttgaaaacta
    25441 tatcgaacat cagcgcgaag tcatcacaag acggacagtc tttgaaaaag aaaaagcaga
    25501 agcaagggca cacattttag aaggtttgcg tattgctttg gatcatatcg atgaaatcat
    25561 tgcgattatc cgcgggtcta aatcagatga cgaagcaaaa gcgacgatga tcgaacggtt
    25621 cgatttatcc gatcgccagt ctcaagctat tttagatatg cgtttacgcc gattgaccgg
    25681 tttggaacgg gaaaaaatcg aaaatgaata ccaagaactc ttaaaactga ttgaagattt
    25741 aactgacatt ctggcaagac cagaacgtgt tacagaaatc atcaagaatg aattagcaga
    25801 cttgaatcaa cgatttggtg ataaacgacg cacagaatta ctagtcggtg aggtcttaag
    25861 tctggaagat gaagatttaa tcgaagaaga agaaatcgtt attacattga caaacaatgg
    25921 ttacatcaaa cgtttggcaa ataatgaatt cagagctcaa cgaaggggtg gacgtggtgt
    25981 ccaaggaatg ggtatccaca atgacgactt cgtcaaaaat ctggtttctt gttctaccca
    26041 tgatacattg ttattcttta cgaataacgg aaaagtgtat cgggcaaaag gatacgaaat
    26101 tccagaatac gggcgcacag ccaaaggaat accaattatc aatttactag gtatcgattc
    26161 gagtgaaagc atccaggcaa tcattgcggt gacgggagaa gcagaagaag gccactatct
    26221 cttctttacg acgcgtcaag gtacagtaaa acgtacttct gtcactgctt ttgctaacat
    26281 ccgaagtaat ggtctgatcg caattggttt gaaagaagac gatgagctcg tcaatgtgct
    26341 actgacagat ggtcaatcta atatcattat tggaacacat aacggctact ctgtcacttt
    26401 caaagaagaa gcagtccgcg atatgggacg tacagcttcc ggggttagag gaatacgcct
    26461 gcgtgaggaa gattatgtcg ttggggcagc cttaatgaag gaagatcaag aagtattagt
    26521 gatcacagaa aaaggttacg gaaaacggac aaaagtatcg gaatatccag tgaaaggccg
    26581 cggaggtaaa gggatcaaaa cggcgaacat cactgaaaaa aatggtccac tagctggatt
    26641 gaccactgtt tctggagatg aagacatcat gctgattaca gataaaggtg tcattatccg
    26701 tttcaacgta tcgactgttt ctcaaactgg acgttcaaca ttaggcgtac gtttgatgaa
    26761 gatggaagct gatacgaaag ttgtcacgat ggcagcagtc gaaccagaag ctgcagaaca
    26821 aacagttgaa gaacaaggat cagaagaata gccatcaaga ctaattgtgt aagctagcaa
    26881 gaatgaccga ttaaaaaatc tggttattcc tgctggcttt tttgattagt tgaatttctc
    26941 ttaaaatatt cgaaactgtt cattctgtat tgcttttgac caaaatagag tgtataatca
    27001 gagcttgtga gtagtctaat taattagata actctccttg ctcttaggaa cctaagagcc
    27061 gaaagtccac agggaggtga atatcaatgg aaaacacgaa atatgaaatc atgtacatta
    27121 ttcgtccaaa cattgatgaa gaagcaaaaa ctgctttaat cgaacgtttc gatgcaatct
    27181 tgaaagataa cggagcagaa gttatcgaat caaaagattg ggaaaaacgc cgtttcgctt
    27241 atgaaatgaa cggttaccgt gaaggtatct atcacatcgt taaagtatct tctccatcat
    27301 cagcaaatgc tgtcaatgaa tttgaccgtc ttgctaaaat caacgacgat atcattcgtc
    27361 acatgattgt taaagaagaa gcttaattgt tgtttcatgt gaaacaatag aaaacgatga
    27421 gaggagatga ctattttgat taataatgtt gtattagttg gacgtctgac gaaagatcca
    27481 gatttgcgtt acacagcaag tggtacggca gtcgcaacat ttactttggc tgtgaatcgt
    27541 aattttacaa accaaagcgg caatcgcgag gctgatttta tcaactgtgt gatttggcgc
    27601 aaatcagcag aaactttagc aaactatgct cgtaaaggaa cacttttagg tgttactgga
    27661 cgtatccaaa ctcgttctta tgataatcag caaggacaac gtgtatacgt gacagaagta
    27721 gtagctgaca acttccaatt gctggaaagt cgttctgcat ctgaaaatcg ccaacaaagc
    27781 ggcggattcc aaagttctgg tcaatcagct ggcggatttg gcggaaacaa taactctaat
    27841 caaacatctc aatcatccaa cggtatgcct gatttcgacc gtgatacttc tgacccattc
    27901 ggctcaagtt caacgatcga catttcagac gatgatttac cattctaaac gaatttgata
    27961 ggagggaaat agaatggcac aacaaagaag aggcggacgt aaacgtcgta aagtagacta
    28021 cattgctgct aaccatattg aatatatcga ttataaagat atcgaattac taaaaagatt
    28081 tatttcagaa cgcggtaaaa tcttgccacg tcgtgtaact ggtacaggcg ctaaaaacca
    28141 acgtaaaatt actgttgcaa tcaaacgcgc tcgtatcatg ggcttgctac ctttcgttag
    28201 cgaagactaa taaatcctag gaattgaatg actgatcctt ttgatcagct attcaattcc
    28261 tttttttctg taaaaataac ctctattcgt ttagtcgctc gaatgacgaa agttatggta
    28321 aaatcaaatt agtcatatat gggaggaaaa ttatggaaaa taaaaacaat catttatccc
    28381 cgaaacctct cttccttatc ctgtttatat taatcgaagt attggtagtc ttaattttac
    28441 catttcgttt tgttagcgct tcggtcattc tattgatgaa tttatggggt gttcgctatt
    28501 ggttgaaaat gaaacgttgg cttattttaa ataaacgtga aaaaatccag caggcttcga
    28561 ctgtagctga aaccaatcta gcttatgtct cagaagtcat gcctgtagga gtgattgctt
    28621 atcagccatc aagccaaaaa atcgaatggc tcaatccatt agcattgaaa atcaaagatc
    28681 aaagtggatt aacagaggaa gaattgctag atactttttt tactgcaaaa gaaaaaaaga
    28741 aaaaccaagt ctatctagca gataaaacat ttcagtttga tatggataca gtaaagggtg
    28801 ttgtttattt taatgatatt acccaaaacc agttgttaaa actccatcag acgaacagtc
    28861 agccggtgat tggtatttta tctattgata actatgcaga tgccattgat aaattggatg
    28921 acaaagagat ttcttatttg aactctttcg tcactacact agtttctgac tggatgaatg
    28981 aataccatgt ctttttcaaa agaatcaacg cagaacggtt tttcttcgta gcacagatga
    29041 tcgatctgaa aaagatgatg gataaaaaat ttgatttgct ggatcgcttt cgagcagaag
    29101 ctgaaaaaca gagctcgcct atcaccctta gtatggggat tgcttatggc tcaagaaccc
    29161 tcgatgaaat cggtggagaa gctcagaata atttagatgt tgctttagtc cgtggaggcg
    29221 accaagttgt cgtgaaagag gtaaaagaag gagcaaaacc tgtttattat ggggggaaat
    29281 ctgctaagaa tgtcaaacgc acgcgtgttc gttctcgagc gatgagtacc gctttgcgtc
    29341 ggatttttga tgaaacaggc gatgtgttta tcatggggca caagtttccg gatatggatg
    29401 ctttaggctc tgcttttggt gtcagttgtc tggcacgctt caaccagaaa aaagcttaca
    29461 tcgttatcaa cgagaacgag atcattccag atgtagaacg gtgtcttgaa gaaatccata
    29521 agcatcctga attagaaatg caactaatct ctccagaacg tgccatagag ctgaaaaaag
    29581 aagaggacct cctcgtgatg gtggattacc ataaaccttc tctatcgatc tctcagggcc
    29641 tatatgagca atttgataag attgtgatca ttgatcacca tcgtcgtggg gaagagtttc
    29701 caagtaaacc tctgctgact tatatcgaat cttcagcttc ttcagcttca gagctagttt
    29761 ctgagctgat ccaataccaa agcagcaaaa caaatcgctt agatcgtttt gaggccacat
    29821 tattgcttgc agggatggtt gtagatacaa atagtttcaa tgtccgtaca actgcacgaa
    29881 cttttgacgt tgccagctat ttaaggtctt gtggagcaga cgcatcctta gtacaatatt
    29941 tattgagctc ggatttagcg acatacttgg agatcagcaa tttgattgct ggaagcgact
    30001 atgtgacttc tgatattgtt gtggcggcag ggacagacga aaaagagtat aatagtgtta
    30061 tagcagcaaa aacagcagat acattgcttt cgatgatcaa tatcaatgca gctttcgtca
    30121 ttacaaagcg gacagacggc ttgattggga tcagtgccag aagtaccggc acgatcaacg
    30181 tccaaatcat catggaatcc ttaggtggcg gaggacactt cacaaacgca gctactcaac
    30241 tggaaaatac gacagttgag gaaacaaaac agaagctatt tgctgcaatc aaagaaaata
    30301 tgaatcaaat atatgataag gagtaatcca aatgaaagta atttttttac aagatgtaaa
    30361 aggaaaaggt aaaaaagggg acatcaaaga agttccagca ggttatgcac aaaattatct
    30421 aatcaaaaat aacttggcaa aagaagcaac gaaaagcagt atcagtcagt tagcaggaca
    30481 aaagaaagca caagaaaaac acgaagctga aatcttggaa gaagctaaaa agttaaaaga
    30541 attcttggaa aaagaagata ctgtagtcga attgaaggcg aaagcagggg aagacagccg
    30601 tttgtttggt tcgatccctt caaaacaaat tgctgaaggg ttaaacaaac aatacaaaat
    30661 caaattagat aaacgaaaaa tcgaattaga aaatccgatc cgttcactag gctacacaaa
    30721 cgtacctgtt aagcttcatc atgaggtgac ggctacgatc aaagttcatg tcgtacaaga
    30781 ataacaaatc ttgatagcga tgttcagctg gtaagtataa ccagaaggaa aaaagacaaa
    30841 ccgaaattta tctgagaaaa cagctgcagc aatgaaagca aaagctgcaa atcgatttca
    30901 gattgatttc ggtttctttt ttgggaacag caaaatagca taaagaaaac gagtataata
    30961 aaagagaact atttttttat tacactttcg gtacgaatga tgacttttct ctcattttct
    31021 tgtaaaatga agcaattgaa gacaaggagc gatacgtatg aatgaagtgt ggcaggatcg
    31081 aatcccaccg caaaatattg aagctgaaca agcggtttta ggctctgttt ttcttgacgc
    31141 agaaacgatc attgatgcca tggagtacat agagccaaaa gacttttatc gtcgtggcca
    31201 tcaaattatt tttgagacaa tgatcgagtt aaatgatcgt aatgaagcga ttgacgtggt
    31261 tactgtcaaa gaccggctgg aacaagccaa tttgttagaa gatgccggtg gtttaagtta
    31321 tctctcagac ttggcattag cagttccgac agcagcaaat atcgtctact atgcgaaaat
    31381 cgttgaagaa aaatcattgc tgcgtacatt gatccagaca gcaacaggaa tcgttacgaa
    31441 aggattcgag caaggagaag aagttcaaac aattttagat gatgccgaac gcagtatctt
    31501 ggaggtttcg gaaaaaagaa atcgaagcgg ctttttatct attgctgaag tactgaactc
    31561 cacgattgaa aatatcgatc gactagctca aaacaatgaa gaaatcacag gtctaccaac
    31621 tggctatcaa ggtctggata aaatgacagc aggtttccag cccgaagaac taatcattct
    31681 tgctgcacgt ccagcggtag gtaaaacagc gtttgcattg aatattgctc aaaatgtagg
    31741 aacaaaaaca gatcgttctg ttgcgatatt tagtttggaa atgggggcag aatctcttgt
    31801 aaatcggatg ctttgtgcag aaggttcgat tgaggccagc catttacgta caggtcagct
    31861 ttcggaagaa gaatggtcga atctgatcgt tgcgatgggg agtctttctc gagcaaatat
    31921 ttttatcgat gatacaccag ggatcaaaat ctctgaaatc cgtgcgaaat gtcggaaact
    31981 agcgcaagaa aaaggcaatc taggcttgat attgatcgat tatttgcagt tgattgaagg
    32041 taacggtaaa gagaaccgtc aacaagaagt atcagatatc tctcgccaac tgaaaaaact
    32101 ggcgaaagag ctgaaagtac ctgtcattgc tctttcacag ttatctcgtg gagtagaaca
    32161 gcgacaagac aaacgaccag tgctaagtga tattcgtgaa tccggatcaa ttgaacaaga
    32221 tgcggacatc gtagccttct tgtatcgaga tgattattat gaaagagaag gcggagatga
    32281 cgatgatgga aacgagccaa aaaatgacaa cgtcatcgaa gtcatcatcg agaagaaccg
    32341 aagcggtgca cgaggaacag ttgaactact gtttatcaaa gaatacaata agttttcgtc
    32401 gctttcgcca agagaagaat tttaaagaag aggttgtgag ccttgagcaa tcccgagagc
    32461 tctcgtaaga agatgcaagg agtaaccgca ggaacgacta gagtacttaa tttaaacaga
    32521 tctccaaagg gattgtgaca aaagtcttgt cacagtccct ttttccgaat aaacggtgtt
    32581 caatcagctg acccttggta ttagctcagc aaacgtcaaa atatgaggaa ctattttgac
    32641 gtttgtttct ctaatactca ggtcaaaacg ctgatcttac gacctctttt ccttaaacgg
    32701 tgttctcctg ccaactcctc ggtcacaagt cacaatatca tcaaacatga gaagcagttt
    32761 tttgaaattg ctccttgtga ctcagagtta aacggcaggc tcacaacctc tttcttaaac
    32821 ggtgttcaaa agcttgcatc tgcggtaata cgcccaatca aacgaaaaat atgagaagct
    32881 atttttgttt ggctgttctt attacttgat gcaggacagc tttttcacaa cctctgattc
    32941 acggtgttcc aaaagtagct tcttcgaaaa ataagtcgaa atttcacaaa aatttgagaa
    33001 gcaattttcg tacattcctt cttatttctt gaagctgacc acttctgtta caacctcttt
    33061 tttaataacc attctaaaaa gataaagttc gttttttaag cgtttttata aaataaaaat
    33121 aaaaatcatt cgattttatt tgaaatatgt atctattatt gatacaatgg ttcaggatta
    33181 aataatatag aacgaggtgt tcacatgtca tctgtagtag tagtaggtac gcaatggggc
    33241 gatgaaggga aaggaaaaat cacagacttt ctcagtgaaa atgctgaagt gattgcacgg
    33301 taccaaggtg gcgacaatgc agggcacaca attaagttta acggtgtgac ttataaactg
    33361 catttgattc cttctgggat tttttataaa gacaagatca gtgtgatcgg aaacggcgtt
    33421 gtagtcaatc ctaaatcatt ggttaaagaa ttagcttatt tacatgaaaa aggtgtagaa
    33481 acaagtaatt tgcgtatttc tgaccgcgcg cacgtaatct tgccttatca tatcaaattg
    33541 gaccaattac aagaagatgc taagggcgaa aataagattg gtacaacgat taaaggaatc
    33601 ggacctgcct atatggataa agcagctcgt gtaggtatcc gtattgcaga cttattagat
    33661 aaagaaattt ttgaagaacg tcttcgtttg aatctagatg acaaaaaccg tcaatttgta
    33721 aaaatgtttg attcagaacc acttgatttt gacgatattt ttgaagaata ttatgaatac
    33781 ggacaacaaa tcaaacaata cgtcacagat acttccgtta tcttgaatga tgctttggat
    33841 gcaggcaaac gcgtgttgtt tgaaggcgca caaggtgtaa tgctggatat cgaccaggga
    33901 acttatcctt ttgttacttc ttctaaccca gtagccggtg gggtaacaat cggaagcggt
    33961 gtagggcctt caaaaatcaa taaagttgtc ggcgtctgca aagcctatac gtcacgtgtc
    34021 ggtgatggac catttccaac tgaattattt gatgaaacag gagaacaaat ccgcgaagta
    34081 ggacgagaat acggtacgac aactggtcgt ccgcgtcgtg taggctggtt tgattctgta
    34141 gttatgcgcc attctaaacg agtttcaggt attaccaacc tatctttaaa ctcgatcgat
    34201 gtattaagtg gattggaaac agtaaaaatt tgtacggctt atgaattaga tggcgaacta
    34261 atctaccact atccagcaag cttgaaagag ttgaaccgct gcaaaccaat ctatgaagaa
    34321 ttgccaggct ggtcagaaga cattacagga tgcaaaacac ttgcagaact gccagaaaac
    34381 gcacgtaact atgtacgtcg tatctcagag cttgttggtg tacgtatctc aacattttct
    34441 gtcggacctg atagaacaca aacaaacatc ttagaaagcg tctgggcgca aatctaagga
    34501 taaaaacgac gactgaatca ggacgttctt accagagcga gtcgaagtgt ttatctatac
    34561 gataataata acttgaagag gtagtgaaag agacgtttag ccttattgcc gataggctgt
    34621 ctcttgaaca ctgtttattc agaataaggg actgtgacaa aaaccgtgtc acagtccctt
    34681 tttccgaa
//
LOCUS       DADQDV010000027        34532 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.027, whole genome shotgun sequence.
ACCESSION   DADQDV010000027 DADQDV010000000
VERSION     DADQDV010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 34532)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34532)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34532
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.027"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(152..2236)
                     /gene="cadA"
                     /locus_tag="J8S10_001353"
     CDS             complement(152..2236)
                     /gene="cadA"
                     /locus_tag="J8S10_001353"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HAZ9629943.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQETKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKKFMQYIASAEQFSTHPIAQSVLEGYAGPLLP
                     TTNIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPLSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKQAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKKEDE"
     gene            complement(2378..2557)
                     /locus_tag="J8S10_001354"
                     /pseudo
     CDS             complement(2378..2557)
                     /locus_tag="J8S10_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308695.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cyclase family protein"
     gene            complement(2761..3120)
                     /locus_tag="J8S10_001355"
     CDS             complement(2761..3120)
                     /locus_tag="J8S10_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HAZ9629944.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            complement(3150..3491)
                     /locus_tag="J8S10_001356"
     CDS             complement(3150..3491)
                     /locus_tag="J8S10_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629945.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERVDQRPSGKLIQHTLVTKENTEEIQKKFAEYLMLEAK
                     KRRIKSIFAQF"
     gene            complement(3488..4162)
                     /locus_tag="J8S10_001357"
     CDS             complement(3488..4162)
                     /locus_tag="J8S10_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAZ9629946.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     KFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTAEICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIAYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            complement(5338..6636)
                     /gene="asnS"
                     /locus_tag="J8S10_001358"
     CDS             complement(5338..6636)
                     /gene="asnS"
                     /locus_tag="J8S10_001358"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HAZ9629947.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            complement(6676..7866)
                     /locus_tag="J8S10_001359"
     CDS             complement(6676..7866)
                     /locus_tag="J8S10_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAZ9629948.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYPLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            complement(7887..8414)
                     /locus_tag="J8S10_001360"
     CDS             complement(7887..8414)
                     /locus_tag="J8S10_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAZ9629949.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEETDHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            complement(8461..11250)
                     /locus_tag="J8S10_001361"
     CDS             complement(8461..11250)
                     /locus_tag="J8S10_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAZ9629950.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLVQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            complement(11397..11597)
                     /locus_tag="J8S10_001362"
     CDS             complement(11397..11597)
                     /locus_tag="J8S10_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAZ9629951.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            complement(12050..12370)
                     /locus_tag="J8S10_001363"
     CDS             complement(12050..12370)
                     /locus_tag="J8S10_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629952.1"
                     /translation="MKKRLLWCLLSLSLSLTSQPVFAEETQRFPITGTRLYKNVYVQT
                     PDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            complement(12873..13991)
                     /locus_tag="J8S10_001364"
     CDS             complement(12873..13991)
                     /locus_tag="J8S10_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9629953.1"
                     /translation="MAKKDKELLSQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            14462..15769
                     /locus_tag="J8S10_001365"
     CDS             14462..15769
                     /locus_tag="J8S10_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HAZ9629954.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWDDKVSISDYAENLSVT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETARLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAE
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            15890..17089
                     /locus_tag="J8S10_001366"
     CDS             15890..17089
                     /locus_tag="J8S10_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HAZ9629955.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYSSTWTFAVI
                     LTYFVVLEIFYSTFYFLIPLVFFSIFAFSYFSEKRRLLNGLLFNIFLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVFLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCIPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYWAQSRATLNPPILLMSGGQGADEKVPE
                     AMAMKQYAMEQGIPERDILVETNSTTTLENMRYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYIAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(17116..18384)
                     /locus_tag="J8S10_001367"
     CDS             complement(17116..18384)
                     /locus_tag="J8S10_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HAZ9629956.1"
                     /translation="MEKQLPSPVRILMYMLKWLVVTAILGVFMGSLSAFFLNSLTFVT
                     DIRLAHPWLLYLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNIAHLFRLDKAEREILVISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVWRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHAYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAVLA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAAYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRIKEKNKV"
     gene            complement(18554..19195)
                     /locus_tag="J8S10_001368"
     CDS             complement(18554..19195)
                     /locus_tag="J8S10_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HAZ9629957.1"
                     /translation="MEQTMKPYQYFFIKREVEQLLNAYSSVNDSKTVQTVQALAAEKI
                     RDVLGYEPSEIDTFLTTVLDVKLTKTQAERALEELKQIVQPFMQPSKPQIEKLFRKVK
                     KLKQPAWNEIDLQAHTYIGWNDPGTQKKFMVYYEDGKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKK"
     gene            complement(19604..20107)
                     /locus_tag="J8S10_001369"
     CDS             complement(19604..20107)
                     /locus_tag="J8S10_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAZ9629958.1"
                     /translation="MTEKWREDEEYMSYVEDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(20230..20994)
                     /locus_tag="J8S10_001370"
     CDS             complement(20230..20994)
                     /locus_tag="J8S10_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HAZ9629959.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKEEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAANKEISTFLVSDEVMDAVSDLPTPQGILAVMALTAE
                     GTPDFSGGWLLLDNVQDPGNVGTMIRTADAFDMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLTEVIPLMKDKGFTVYGTELNEEAHALDKVEKSDNFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            21102..21377
                     /locus_tag="J8S10_001371"
     CDS             21102..21377
                     /locus_tag="J8S10_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HAZ9629960.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            21937..22887
                     /gene="yidC"
                     /locus_tag="J8S10_001372"
     CDS             21937..22887
                     /gene="yidC"
                     /locus_tag="J8S10_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HAZ9629961.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVVIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPANNKQATKQIKQPKNSTNNKGRNAGKQQKRK"
     gene            complement(22933..23334)
                     /locus_tag="J8S10_001373"
     CDS             complement(22933..23334)
                     /locus_tag="J8S10_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAZ9629962.1"
                     /translation="MSRQLVLISHGKFCEELKKSTEMIMGPQEDIYTLPLLPEDGTET
                     YKQKFLTVTDSLNDFVVLCDLLGGTPANIISKLIMEGQQITLYAGMNLPMVIEFINSQ
                     MIGSEPEFVRAGCESIVSVNELINGIAEEEE"
     gene            complement(23348..24157)
                     /locus_tag="J8S10_001374"
     CDS             complement(23348..24157)
                     /locus_tag="J8S10_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAZ9629963.1"
                     /translation="MTKSNYKLTKEDFKQINRRSLFTFQLGWNYERMQGSGYLYTILP
                     QLRKIYGDNTPELKEMMKTHTQFFNTSNFFNTIITGIDLAMEEKEGIASKETVSGLKA
                     GLMGSFAAIGDSVFAALIPTIFGALAANMATDGNPIGVFIWIFAQIVVMVFRWKQLEF
                     AYKEGISLVTTMQSRLTALTDAATLLGVFMVGALVATMINVKFSWAPTIGDVTLNMQN
                     YIDMILPKILPAGIVGGVYWLLGKKNMTPTRAIFIVLIVCVALSALGVISK"
     gene            complement(24144..25034)
                     /locus_tag="J8S10_001375"
     CDS             complement(24144..25034)
                     /locus_tag="J8S10_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAZ9629964.1"
                     /translation="MDIQWWQILLLTLYAGYQILDELQIYSSMSAPVFAGLYAGLVMG
                     DLNAGLIIGGSMQLTVLGVGTFGGASKIDANSGTILATAFSISLGMNPEQAIAAIAVP
                     VASLMIQLDILARFANTYFAHRIDRHVEDMNYQAIERNFLMGALPWSLSRMIPVFLAL
                     AFGGGLVENVVSVLNGNLKWLGDGLSVAGAVLPAVGFAILLRYLPVKKHLSYLILGFT
                     ITALLATLFSNVQLLGTSVASVVKDLPATFNSLPMLAVALIGLALAMISYKNDQNKDH
                     QPLASEPSHSVEGEIEDDEI"
     gene            complement(25047..25526)
                     /locus_tag="J8S10_001376"
                     /pseudo
     CDS             complement(25047..25526)
                     /locus_tag="J8S10_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724290.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
     gene            complement(25702..26643)
                     /locus_tag="J8S10_001377"
     CDS             complement(25702..26643)
                     /locus_tag="J8S10_001377"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexose kinase"
                     /protein_id="HAZ9629965.1"
                     /translation="MITTVTLNPSIDIAYTIEELNLDKVNRVETVNKTAGGKGVNVAR
                     VLNLLGEEVIATGLIGGQHGEYLKNQLDQLGIMHQFVPIKGETRDSIAILHSSRQTEL
                     LERGPFITKKEQQTFTDHFEQLLEISDIMTISGSLPQGCPLDYYKQLVALADKKGKDI
                     LLDTSGKFLLEVLEGKEKPLLIKPNLEELGELIGQRICSSIQLEKIQSLLAHPIFEGV
                     PWVVVSLGERGAVAKVAQCFYEVIIPKISVVNPVGSGDATLAGSAHALSKRQSIEEIL
                     AFSMACGMANAQQEKTGWIDPMKVTMLMKHIQVKKIK"
     gene            complement(26640..27635)
                     /gene="lacD"
                     /locus_tag="J8S10_001378"
     CDS             complement(26640..27635)
                     /gene="lacD"
                     /locus_tag="J8S10_001378"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HAZ9629966.1"
                     /translation="MNEEKNRAMERLSTKDGIISALAIDQRGALKKMIKSLGKEPSED
                     QISEFKELVSAELTPYASAILLDPEYGLPAAKVRAKETGLLLAYEKTGYDATTPGRLP
                     DLLADWSSLRLKEQQADAVKFLLYYDVDEAPEINHLKHVFIERLGSECEGENRPFYLE
                     LVSYDAQISDSSSPEYAKVKPHKVIEMMKEFSDPKYKVDVLKVEVPVNMNYVNGYSTG
                     EFIHSKEEAAAFFKEQSEATPLPFIFLSGGVSTELFQQTLIFAHESGSTFNGVLCGRA
                     TWKDGVKAYVENGKDGAIHWLRTNGRENIETLNKVINETATPWFNKTKSKKVKMK"
     gene            complement(27628..28824)
                     /locus_tag="J8S10_001379"
     CDS             complement(27628..28824)
                     /locus_tag="J8S10_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAZ9629967.1"
                     /translation="MFELSKNKLKQIGAAITTQEIKQQPDLWKETIDRLMQSQENLAL
                     FFDQIKKEANGRRIRVIFTGAGTSQYIGDTLLPYLNEHGDNQFFIFHSFGTTDIVASP
                     KEFLFPNEPTLLVSFARSGNSPESVAAVQIANEQVETLFHLTITCAKEGMLAKNAQDD
                     KQNYLLLMPERANDAGFAMTGSFTCMLLSALWIFDQTAMEKKERYLEQLVKIGQDLLS
                     RDQEIQKLLPDFFERIAYLGSGSLAGATREAQLKILELTAGKVATIFDSSMGFRHGPK
                     SFLNSETLVVGFVSNQPYTRNYDLDILEEIKEDRVTANVIAIAQPGTIDFSGMTVLLE
                     DSVSKLPDAYLALAMIMTAQIIALYTSIKVANKPDTPSPTGTVNRVVKGVIIHKYETE
                     GEMTDE"
     gene            complement(28842..29570)
                     /locus_tag="J8S10_001380"
     CDS             complement(28842..29570)
                     /locus_tag="J8S10_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAZ9629968.1"
                     /translation="MESSNKGKSLYYQLVDLLKDRIETQMTPHDKLLSERELCQHYGV
                     SRTTVRLALQELENQGYIYRRHGKGTYVSDLSDKSSNLAGAYSFTEEMREIGRVPKTV
                     ILEFRQMEANKRIAKNLNIHLGETVFKLKRLRLADEEPLMVERSYLPAKLFMGLDLPL
                     LESKPLYDVFSQDYEQQVQLADEEFYASIVQKKDAVVLRIADGAPVLHLTRITYNVKN
                     EIIEYTDSVARADQFHYKIRHIRK"
     gene            complement(30011..30985)
                     /gene="lacD"
                     /locus_tag="J8S10_001381"
     CDS             complement(30011..30985)
                     /gene="lacD"
                     /locus_tag="J8S10_001381"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HAZ9629969.1"
                     /translation="MKKMSIEKQERLKRLTDEAGIISALAIDQRGALKKMINQYKEAT
                     SEDIIQFKQMVSQYLTPYASAILLDPEYGLPAAALREKECGLLLAYEKTGYDAKMPGR
                     LPDLLNSWSVKRLKEVGADACKFLLYYDVDEPVEINVQKQIVIERIGSECEAEGIPFF
                     LELLSYDATIGDPSSLDYAKVKPHKVIEAMREFSKERYQVDVLKVEVPVNMRFVEGYG
                     QDTCYSQAEASAYFYEQSKVTEQPFIFLSAGVSAALFQDTLRFAKQSGSTFNGVLCGR
                     ATWAKGVAPFVTEGEEKASSWMLEEGKQNIKELSTLLEETATSIYVNK"
     gene            complement(30982..31440)
                     /locus_tag="J8S10_001382"
     CDS             complement(30982..31440)
                     /locus_tag="J8S10_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAZ9629970.1"
                     /translation="MTIIHEENIFLQQPLDNQEEAFKFLAKQTFCLGIAHDEKEVYQK
                     LLEREKEGTTGIMSGFAIPHAKSQTINEPSLIIVTLKKGIEWNSLDRQSVDFIFALFI
                     PDSEAGTTHLKLLSLVARSLMRKEVTEQLRAAKSKIEIATILTKEIGEDI"
     gene            complement(31437..32900)
                     /locus_tag="J8S10_001383"
     CDS             complement(31437..32900)
                     /locus_tag="J8S10_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAZ9629971.1"
                     /translation="MGKYQLIAATGCPTGIAHTYMAQEALEQAARKKGITIKVETHGQ
                     IGIENELTAEEIKQADAVIIAADKDVHSERFVGKRVIDVSVSTGIKDAQRLIDEALAG
                     KGTVLADNEAADTLEPEAISGANFGRSIYKNLMNGVSHMLPFVVAGGVLIAISFAVWG
                     IYSSDPDHAQYNATAAMVKAVDDAAMGMMVPVLAAYIAEGIAKRPGLVVGFVGGIVAM
                     NGGTGFLGGILAGFLAGYFILFLQKLLIILPKQLDGLKAIVLYPVIGVAFIGIVMSLL
                     AGPMKAINEGMMSFLAGFEYSNPLVLGVIVGCMCAFDMGGPVNKAAYVTGTALLTQGN
                     TTFMAGASAACIAPPLITGFATLLFGKYFDTNDRNAGLVNFILGSTHITEGAIPFAAK
                     DPIRVLPTMMLGSSIAAVLTYLFGVQVPAPHGGFLVLPVVTGKIQWVTAILIGSIVGG
                     VILGLIQKKRVTDKDKKRDNKATNRTVIEEGRAGGLS"
     gene            complement(32882..33814)
                     /gene="pfkB"
                     /locus_tag="J8S10_001384"
     CDS             complement(32882..33814)
                     /gene="pfkB"
                     /locus_tag="J8S10_001384"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010779385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HAZ9629972.1"
                     /translation="MSIYTCTMNLAIDLFIETDEMHPFMVNRTKEDDIQANGKGVNVS
                     LVLKMLDFPSTALGFSAGFTGKYIEDYLQQKQIQTEFIEVPGMTRINVFTQVNQTGEE
                     YKLVNQGPEIPQTAVHNFLNQIRALQAGDYLCVSGSLPRGLSPKVLIEISRICLIIDS
                     SDQEVMDCLPYRPFLLKPNEEELSSWFGRKMVTDEDYFVYGQRLVESGAENVLLSLGE
                     KGAILFTKDRVIRGNSPKGKVVNTACAGDAMLGTFLAGYMNRRSLDETLRKSIAAGSS
                     TAFRKGLTDFLDVEELSKQIKIKEERFERWENIN"
     gene            33956..>34532
                     /locus_tag="J8S10_001385"
     CDS             33956..>34532
                     /locus_tag="J8S10_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAZ9629973.1"
                     /translation="MNHKLSETEQYLWNFIEHLILEIPNYSIVKLSEQANVSTATIVR
                     TMKKKGYEGFTSFKHHLKEGENKNINFSFLDKVDKGIRRAILKNEQEVVRTINMLEIG
                     NIEDAIQRIKFADRVFVFARGFSEMIGQEMLVKLQLTGKNCQMHTDPEIIKSISRKLT
                     KKDSVIFVSLNGEKTNKNIKNKIYVFIFQFFK"
BASE COUNT        10065 a         7443 c         5876 g        11148 t
ORIGIN      
        1 aaaataagtt attttctttt atttcattga ccttattgaa tttcaagcta ttttgaattt
       61 tctgcaaaat taaaaacatt agttatttta taatcctatc tattttcttt acatttttca
      121 ttaagaaaag gatataaaaa aaagaggacg ttcattcgtc ctcttttttt acatgcaagc
      181 ttcgcatggc attcaaaaca gctaatactg tcaccccaac atctgcaaat actgcatctc
      241 ccattgatgc aaaaccaaaa gcacctaagg caagtaccaa aatttttatc ccaatagcaa
      301 agacaatgtt ttgtttgacg attttcaatg ttttctttgc taaatggatt gcttctgcaa
      361 tcttcgatgg ttgatcattc atgatgacta catctgctgc ttcaattgca gcatcgcttc
      421 ccaatccacc cattgcgatt cctacatctg ctcttgctag caccggtgca tcgttgattc
      481 catctccgac aaatgcggtc tttttattgt ttctttgtaa gatttcctct aaccgctgca
      541 ctttatcttc aggaagcaat tcgctatata tcttgtccac gcctacttgc ttcccgatat
      601 gatcagcaat ttttttcgag tcgcccgtca acatgactgt gttcttcaca ccagcctgtt
      661 ttaattgaac caatgcgtct acggcatctt ctttcaaggt atctgcaata acaagataac
      721 cactgtaact ttgatcgatc gctagataaa gcaatgtacc gatttcttga cttaaaggaa
      781 aagagatttc aaatctttcc atcaatttgt gattacctgc taatacttgt ttgccatcaa
      841 cttcagctaa gatcccttca cctgcaaatt cctggatatt agttgttggt aaaagcggac
      901 ctgcgtagcc ttctaaaaca gattgagcaa tcggatgtgt agaaaactgt tctgcactcg
      961 caatatattg catgaatttc tttggatcga tttttgtatc gatcgtctgg atcgaaaagt
     1021 cacctttcgt taatgtgccg gttttatcga ataccactgt ctcggtttgc gcaagcaact
     1081 ccaagtaatt tgaacctttt actaatacac cgattttact tgcgcctccg ataccgccaa
     1141 agaaactaag tggcacggaa atcactaatg cacatggaca tgagatcact aaaaatgtca
     1201 atgctcgata gatccattca gaaaacgccg ctccagaaac aacaagtgga ggtaaaacag
     1261 ctaataaaac ggccaatcct acaacgactg gtgtgtaata gcgcgcgaat ttagtaatga
     1321 aattttcagc tggtgctttt ttactgctgg cattttctac taattctaat aatttgctga
     1381 tagtagaatt ttcataagat ttttctactt gaactaaaaa tggtttattt ttattgataa
     1441 atccgcttaa tactgtttca ccaacatata cagatttagg gactgattct cctgtaagtg
     1501 ctgacgtatc gactaatgat tctccttcga tgatcgttcc atctaacggt acacgttcac
     1561 caggcttcac aagtacaaac tgaccgatct gcacgtcttc agggttcacg gtcatcaatc
     1621 cttccgtcgt ctgcacgtga gctgtttctg gacggatcgc catcaattcg cgaatcgatt
     1681 ttcttgaatg actgactgcc aatccttgga aatactcgcc gatttgataa aatagcatca
     1741 ctgctacggc ttctggatat tcaccgatca acatagcgcc aatcgtagca acagacataa
     1801 gaaaattctc atcaaagatt tttcctttga cgatattcat cactgccttc ttcactacat
     1861 catatcctat cagcagataa atcaataaat accctatcaa gcgaattggt tcattaaaat
     1921 caaataatag caataaagcg atacctgcaa gggaaaataa aatccggaac agcgtatttc
     1981 tctctttttc atttccatgt tcagatactt tttccttatc tatttctgtt actttgacat
     2041 ctggttctaa ttccttcact actttttttg tttcttgttc aatcgtagcc aaatgatctt
     2101 cctctgcgtc aatcgttagt tttccagaag tgaagtttac cgttgcttcc ttgactccat
     2161 tgatcttctg aactcctttt tcgattttca ttgcacagtt cgcacaatct aaaccttcta
     2221 atctgtaact tttcatttta atgacctcct cgcctcaaca tatgaacatc tcttcataac
     2281 taattataaa tgaatggtta ttcatatgtc aaggtatccg aaagaaaaaa tgaaaaacat
     2341 ctgcatcgga aaatttcttc catacagatg ttttggctta ttctttcttt ttctcttcga
     2401 tcattgcccc tgctcttatc caacccgcac ttgccttctt gatcttgaca ggatagcaac
     2461 taagtttgaa gcctgttgct ggcaatttgt ctaaattcat taatttttcg ataggacaat
     2521 atcttttttc aatccctgca aaatgtcctt cccagatatt cgaagctcca ctacgctttc
     2581 aaaaatatag aaagagttct ttaatgaaaa ttatttcaac tttccataaa cagtaatccc
     2641 atataaataa aagacgtaaa agtcacatgg gagaacttat acaggaaaac acatagagtc
     2701 aggtgaaata catgtatccc acctgactct atgcgttttc taacctttat tattctcttt
     2761 ttatacaatt tctgcaccga atggcatcaa cgccaatcga gcaagtttga aagattgctt
     2821 ggcaaaaggt atccctatga tcgtgataca tagaaggatg ccgctgacga catgtgcgag
     2881 agcaattggt aggcctgaaa cgatcagcca gatgatatta acgatcaatg acatgccaga
     2941 ctggtgataa attacttctt tgccaaaagg cgcaaaagaa agggaggcga tcttaaaaca
     3001 ttgcataccg attgggatac ctatgatcgt gatacaccaa agtatccccg ctgctaacca
     3061 gctaagacca ccgattagtc cgccgaatat aaaccagatg acatttccta aacaactcat
     3121 tgtatttctc cttctattac tgtttttgat taaaactggg caaaaattga ttttattctt
     3181 ctttttttag cttccagcat caagtattct gcaaattttt tttggatttc ttccgtattt
     3241 tcttttgtta ctaatgtgtg ttggattagt tttcctgatg gtcgctgatc cacccgttct
     3301 tctgactgtt gcacgtccgc ttgcgcaaat ccgataatcc gtttttcttt tgttacagca
     3361 acgagcaata gtttattctt atcatttagg tcagctgccg tttttgcttt tacgaatgat
     3421 tctggatgat cagtaatcag ctgattgatt tgaggtaaat cttcttttac tgcccaccgt
     3481 atttccatca tttctcactt ttctttcgct catttttatc tccactaaaa aaatcgactg
     3541 cggcaattgc atctatccag ctttgtgcaa tgatctcatg tccgccaatc gttgggtgga
     3601 ccccatcttc tcttgtatat ttcgaaaaac cataagcaat ccctaaagca ttgaatatgc
     3661 catctaaagg aaccagcaat gcgccatatt ccttagcaag tttacgaaca atttggattt
     3721 tagggtctaa gtctttacgc cagccatgac ggtcgtcggt tataggaagt acaaacggct
     3781 ccatcaagat gatgttgcag atttccgctg tttgaagttc atttagtaat tttcgataaa
     3841 cggattcaaa ttgctgcgca gatttctcag ttccgaatat agcctgatcg ctagtattat
     3901 gccaggtatc attgattccg atcaaaatcg atacatagtc aggttgtaaa gctaaacaat
     3961 cttcttgcca gcgtacttgc agatctgcaa ttttgtctcc tcctatccca cggttcatgc
     4021 attcaaattt catcgttgga tattgggaga ttagttttcc ggcaatcaaa agtggataac
     4081 ctttacctag atcagttgct tctgctcggt ctcttcctgc gtctgtaatg ctgtcaccga
     4141 taaataatat acgttttttc atttgtcaaa aactcctttt tgaataaaac gatgattttc
     4201 ttccttatat tatcccataa gccctatcaa gacgaaagag aaaatatatg tataaaaaat
     4261 gacaccagcc tagtcccttc aatcaattga atgaacgctc atcaagtgtc tagtttttta
     4321 tacttttttt cttaacgtgc cggattcccc ttgattcctt cgttgtttgg tccagagaaa
     4381 tcgatcacac ctaagcttcc gtcaatcaga ccactgatga cgccatcaga acatatattt
     4441 ataggctcat ctaagacttc cagtaaatgt tcttttacta atatctcttc tagattgctt
     4501 gggatagatt ggtcataact ttatctggtc cgatgatttc aaggatgaat taaacttaca
     4561 tatggatcat tgcatgctga aaatacggac ctactccatc ttcgaatgtt actattagtt
     4621 tgttttcagg tactagatgc tgctttattt caacagcaga agcatcatca aatcagattt
     4681 ccatttgaat aaccttcttt gtatatgttt gattgattgc gatttcgtta tagaaccttg
     4741 tgaatcaaat agcaatttct tttgctttct tctcttgtct gctggaaact tcctttatcc
     4801 cgtattttaa aaaaagaact gcgagagttc gcagttcttt tttttaaata aacgttgctc
     4861 tccggccaac tcctcggtca caagtcacaa tagtcatcaa acatgaaaaa ctgttttttg
     4921 aaattactcc ttgtgactcg gagctgaacg gcaggcgcac aacctcttga tataaacggt
     4981 gttcaatcag ctgaccctcg atattagcta aaaaaacggt aaaatatgag aagctatttt
     5041 tccgttttgt ttctctaata ctcaggtcaa ggcactgatt tcacaacctc ttccttaaac
     5101 ggtgttcaaa agccagtttc tcggtattaa gccaaattta tgcaaaaatg tggaaagcca
     5161 tttccacaaa atttttctta atactcgaaa ctaaacagct ttttcacaac ctctccacta
     5221 aacggtattc aaaagcttac atctgcggta ataagtcccg ccaattcaaa aacatgaaca
     5281 gctgtttttg cttggctgtt ctaattactt gatgcagaac agctttttca tcacctctta
     5341 tggataaatt cggttcaaca aacgtgggaa tggaatagct tcacgtacat ggtcgatacc
     5401 agcaatccaa gtgactgttc gttcaaggcc tagaccaaaa ccagagtgcg gaacagaacc
     5461 gtatttacgt agatcaagat accatgaata ttctttttca tccaaaccgt gattacggat
     5521 ttgttctagc aagaaatcat agtctgttgc ccgttcgctt ccgccaataa tttcaccgta
     5581 accttctggt gcgatcatat ctgcacaaat taccacgtct tctcttgttg gatgtggttt
     5641 catgtagaat ggcttgatgg cttttggata gtttaggata aagacaggct gttcgaatga
     5701 attcgcaatg aacgtttcat gaggtgaacc aaagtcttcg ccccattcga tgtcatcaaa
     5761 tccatttttc ttcagtaatt cgattgcatc atcgtaagta atacgaggga atggcaattt
     5821 tgtataagtt tttaagactt ctttgtctcg tcctagtaca tctaatgcat attcgcaatg
     5881 atctaaaaca ttttgtacta agaatgctac atattgttcc tgtacttcta agctttcttc
     5941 ttgatgagtg aaagccattt ctggttcgat catccagaat tcgatcaaat gacgtcgtgt
     6001 ttttgatttt tcagcacgga aagtcggacc gaatgaaaag acttttccga aagccatagc
     6061 agcagcttcc atgtataatt ggccactttg agataaataa gctttttgat caaagtaatt
     6121 tgtttcgaat agatccgtag tgccttctgg tgcagaacca gtcaagatcg gcggatcgat
     6181 tttgacaaaa tgatgttgat taaagaattc atacgttgca cgaatgattt catttctgat
     6241 ctgcataatc gcatgttgtc ttgaagaacg cagccataaa tgacgatgat ccatcaagaa
     6301 atctgttccg tgttcttttg gtgtgatcgg ataatcgtgg ctctcgctta ccacttccac
     6361 atttgtaatt ccgatttcat aaccaaattt tgaacgactg tcttcacgga tttctccagt
     6421 tactaacacg gatgtttctt ggtgtagatt tttagctgtt tggaaaactt cttccgacac
     6481 ttcgcttttt acaactacac cttggaaaaa ggctgttccg tctcttaatt gtaaaaatgc
     6541 gatttttccg cttgatcgct tatttgcgac ccaagcgccg attgttactg tttctcccac
     6601 atggtttttc gaatcgatga tttgaatttg ttccacgtat gactctcctt ttatattcct
     6661 tgaatttctt caggattaat tttgactttt actctcaata aattgcttga ttctgcgtac
     6721 cgcttcttct aacgtagcgc gatcagtggc ataactcatg cggacatttt ctggtgcccc
     6781 aaagccttcg ccagtcacaa gcgctacccc tgtttcttct aaaagatctt ctacccattg
     6841 tgtgacattt tcatacttac acatgcgtag cgtttctttt acattaggaa aaagatagaa
     6901 agctccttgc ggcttttcaa gagaaacacc cggcagttct gccacaagcg gatataacgt
     6961 attcaggcgt tcttcaaagg cgttccgcat ttcttctact gtatcttgct cacctttcaa
     7021 tgcttcaaca gctgcatatt gactgactgc tgtcggattg ctagttgatt gggaagcaac
     7081 agcgatcatt ccattgatga tcacaggatt tcccaccgca taaccaatgc gccagcctgt
     7141 catcgcatat gttttagaca cgccgttgat gatgatggtc tgatttttga ttgcttctga
     7201 aatcgttgca attggagtaa actcattgcc attataaact aaacggccat aaatatcatc
     7261 agcaactatc aaaatatcat tttttactgc ccattcaccg attgcctgca gttcattctt
     7321 gctataaatc attccagtcg gattcgatgg agaattgatg attacggctt ttgttttttc
     7381 tgaacgtgct tgttctagct gttcaacagt aactttccag ctattggatt cttccccttt
     7441 cacaaagaca ggaagtcctt ctgccagttt tacttgctca ccgtaactga cccagtaagg
     7501 cacaggaatg atgacttcat cttgcgggtc aaggatcgtt tggaaaaggg tatacaaagc
     7561 aaatttcgct ccgtctgtta cgactgtttg tgaaggttca tagacaagtc catagttttt
     7621 cttcagataa tcaacgattg cctgtcgaag ctctgggatt cctgctgttg gtgtataata
     7681 gctagctttc ccattgcgga ttgcttcgat tgctgcttct tggatgtttt ctggtgtcgc
     7741 aaaatccggt tctcccacag tcaaactcag cacatctctg ccttttgctt ttaatgcctt
     7801 ggcctttgcc gcagctgcca aagtgacaga cggttctaat cgttttgttc tttttgataa
     7861 ctccatccca ttcattcctt taccttttaa attcccttga ttgtcttgac ttcatctcca
     7921 gattcaaagc caatcaggta ataattcagt ttcccatttg tttcttttcc tactacttcc
     7981 cacacaggct gatcatcata catccctaaa gcagcttttt cgatttggat ttcaggatgg
     8041 gccgcagcaa ttgtctgttt tgcttcgttt tcagtcagtc cctttgtttg atccaatact
     8101 tttacttttt caccagattt aggaatgata acggcgattt cttttccttt atcatttgta
     8161 cctgtcagtg aaaagtatgt cttctttcga gtaaaccaat aaaaatgatc ggtttcctca
     8221 agatttgcat atttctttgc gatttctact gcttctttct tcgcctgcac cgccggacga
     8281 ctggaacgca agtaaaaaat cgagctgatc acgatgaccg ctaataaaaa tacgatcaag
     8341 ccaagtaaca cgcgattaat cgttttttcc tttgtctgtt ttttcttcaa gggtcgtcgc
     8401 tcctttatct tcattccttt tcattatagc agattttaat tatgaaaaaa gacagctcct
     8461 ctaacttcct tcttcatttt tctttaagaa ttcatggata tcctgataga tttcctccat
     8521 agctagctct ttgatcggta cttttttcgg taatgcatgg atgatccgtg cgccatattt
     8581 tgcagtgact agtcttcgat ccaaaataag caatacgcca cgatctgtct ccgtccttat
     8641 caagcgacct aatgcttggc gtaacttcaa agctgcttta ggtacggatt cctggtaaaa
     8701 aggattgatc ccctctgatt ctaaataagc gttcctagct ttgaccatcg ggcgaagcgg
     8761 attatcgaag ggtaaacgtg tgactacaac gatctgcaaa gcatctccag gcaaatctac
     8821 accttcccaa aagctgtcag cgccaaacaa tacgcttttt tctgacaaaa tgaagcgttt
     8881 caaaagcttc tcccggcttc caccaaaccc ttgagctagt atttctcgtc ctttttctag
     8941 catagacaga tgcattttct gatagacctt ctgcaaaaca tcatgagaag tgaataacac
     9001 aagtattggc cgatcttctt gttcgatcag acctgtaagt gctgtctcta aataatcgat
     9061 atatgcttga ttgctgactt gatggacggc aggtgcctct tttggcacat agatccttgc
     9121 ctgtttctca taatcataag gagaggcaat cactttaaga ggtgctgctt caatgccaag
     9181 cctcttagag agatagtgtc gattagggcc gatcttcagc gttcctccaa tataaagaat
     9241 acgatcatat cgaggatacc aaacagtcga cggcaacata gccgcttgaa aatcatggag
     9301 atgaaaaatc atctgctgcg ctgtgttccc aggaacgaac caatggatca aatgatctcg
     9361 ccagtcttcc agccattgat ccatcagcaa gtattgcttg tctaattgat caaataggct
     9421 atataaactt gctaaatcga tccgcatctg gtttgtccag ctttcttgga taatctcaaa
     9481 agtcagacgc atttgtgact gtagctgctg gatctcctga taaaaaagct gcaggtgatc
     9541 aatggctgtc ccagattcca gtggcagctg atccaacatc tcttttgtca tcatgacttc
     9601 ttctggatac tgtccgttag gttgcttgcc gctcactaaa ctcattaatc cttctgccat
     9661 acaaatctgt gcttcgcata gcgcagaaag ttcttctcga taaatcgata accagcgtaa
     9721 ggcttcatgt tctttcggta aatagctttg tattcggtca aacagctgat ttggttcttc
     9781 taattgctgg atttgtttat ggaaatagtt aatacttaat cgtttgtcat ttactttttc
     9841 agcgatttcc ggcaaatgat gtacttcatc gatcaacaaa aatggactag ctggaagcaa
     9901 tggttctttt cgctgtgttt cttgtactaa aaacgcatga ttgacaatca aaaaattact
     9961 ttgcctgatt ttcttttgca agaaacgaac aaagtcttgt tcgtaaaatg actgatttct
    10021 tgctaaaaat ccaatacctc tgtgcgcgat atctgcaaag aatgaatggt tcaaatttgt
    10081 taaatgtaat tcatccaaat caccagtctt cgtttgcgtc agccaaacta agaccgccat
    10141 ttgatacaaa gcatattgtt tttgttctgg cggttccaca agtgtgcctt taaaacgctg
    10201 caaatcaata tagtggcgat agcttttgat aattacaggt tgtatgggct gatctagcaa
    10261 ttgattcagc aatggaatgt ctttttctat gatctgctgc tgcaaaacta gcgaaacggt
    10321 actgatgaca gcgggttttt caggtgtagc caaataactc aatggcagca gataaccgat
    10381 tgttttaccc attcctgtag ctgcttcgat catcaaatct tttgattcat cttttgtgaa
    10441 atggtcgtag accgcattca tcagtctgtt ctgttctttt cgatacatca gtgttttacc
    10501 aaacattttt tcttttgctt gtttttttct tggatatgtc cgctcgccat aatggacgga
    10561 tgtgaatagt tccacttctt ttttctgcaa agctagccca tcgacgattt ctaatgaggg
    10621 atcaagtggc tctggttttt ctttcatttc ttcaatcaca tgataaatga aacgactcgt
    10681 atccatacct gtgtgtctac ttaatcgcgc aatctgctct aacgtgatga ttggcaattt
    10741 tctcatccgt tcttcgatca gcaaaagaag ttgacctgtc acttcggcat cactatctgc
    10801 ctgatgagga ttctcatgaa taaatccaag gctttctgac aaatcagcta agcgaaagct
    10861 tggttccgtc ggcaagaaaa tttgtgcaag ttctactgta tcgatgcctg gtatcttcaa
    10921 actaggaagt ccgcatcgca tgagttcatg gttcaaaaaa ttataatcaa aataaatatt
    10981 atgcgcgaca aatatggtgt ctgccaaaag attgtaaatc gtttgggcga catcttcgaa
    11041 ataaggcgct ttttggacgc gttgattcgt gatccctgtt aaatgctgga tttgttttga
    11101 aatcttccgc cctggatgaa tatcgatcga aaaacgtgaa gtgatccgac ctgattcaat
    11161 catgacgcag ccaaattgga tgatccgatc ttcttttgga ttcgtcccag tcgtttcgat
    11221 atcaacgact gcataagttc ttggtttcaa aatatcttcc tcttctcctg cctctaatgt
    11281 tcttttgaaa ttatactaca aagtgcagaa aaatactctc atcgcttttt aaagaaaata
    11341 gacaaaaacg cccagacacg caaatgtctg ggcgtttatt ttttagtata ggttaattaa
    11401 gctttagtaa cgtttgttgc ttgaggtccg cgttggcctt cttcaacatc gaaagttact
    11461 gcttggcctt cttctaaagt tttgaatccg tcgccttgga tagctgagaa atgaacgaat
    11521 acatcgtttc cgttttctgc agtgatgaat ccaaatcctt tttctgagtt aaaccatttt
    11581 actgtacctg tttccataat aaaaatcctc cttgtgtatc aacacatatt ttgcaattac
    11641 ttgaatggtg tatatctgga agatgtttat ttgaaacaag ctaccacaga ttaccgaaca
    11701 aaaactactc ctatagtata tcataccgtt tacaaaaaag ctagagtttt tcgacttttt
    11761 ttattaaaaa aagttttctc agcgattaca taaagtgaaa aaccgaactt ttttttaaaa
    11821 taaacgacat attgttcagt tggtgttttt ttgctctgat gttctttttt aaactaaaaa
    11881 aattattctt tctgactact tatcggttct gtttcaacgg tcgaggctgg ggaagattct
    11941 ttagtaggtc tgatgttctc atggtatttc tgatagccta tgacagttac cagaagaaca
    12001 aggcaaacca atacgaccaa cgagattagt ttttcttttt tgctcatatc tatacctcat
    12061 aaataacagg atgatgtcca tcatatttct gagtatgagt aaaagcaaaa gctgcagctg
    12121 tagaatgtaa gaaatgccag caactttcat aatcacaggt cggacagtac caaaagtaac
    12181 caaatcttgg ctgcaaagac cgttcttctg tttcaggaat cgcagaatca agatctggtg
    12241 tctgtacata aacatttttg tacagacgtg tgcctgtaat aggaaaccgc tgtgtttctt
    12301 cagcaaaaac tggctgactt gttaaactta gggatagaga cagcaaacac cataacagtc
    12361 tttttttcat aaagacctcc ttatcgataa gtttttccca attaaaatca tatctcaaga
    12421 acgcccgtta ttcacatttt gttcataaat gatgtttttt gtatcataat cgtcaaaaag
    12481 aggtcgtgac cacgtcacaa cctctttttt aaacggtgtt ccagaagtag cttcttcgga
    12541 aataagccga aatttcacaa aaatttgaga aataattttt gtcaatctct tcttatttct
    12601 tgaagctgac cacttctgtc acaacctctt ccttaaacgg tgttcaaaag cttgcatctg
    12661 cggtaataag cccaccaaac aaaaaatatg aagagctatt tttgcttgct gttcttatta
    12721 cttgatgcag aacagctttt tcacaacctc tcatacacgg tgtttaatca gctgaccttc
    12781 ggtattagct caaaaaacgg caaaatatgt gaaactattt ttccgtttgt ttctctaata
    12841 ctcaggtcaa aacactgatt tcacaacctc ttttaataac gaagaatcgc tgtcagactc
    12901 ttttcatctg gcgcatcttt ttgatccaaa ataaacactt ttccgccatt aatgatcaca
    12961 tcatctgcta atgcattcaa cacttgacgc cgatcatatt ctgtttcagg atcttcaccg
    13021 aaaccatcag ctaagtttga cgtagcgata aataaatgtg acacttttcc ttctttcgca
    13081 gctggaacga tatcaactaa ctgatcgatg aatttcttat ctaagagttt attgtattct
    13141 tttgattctt gagctgcgag ttcacttgac agcttcttcg ccccttcttc gatatctcta
    13201 aaggatagct gcgcaggaga agcagaaatc gcaacgtctg cacaataata gggattttta
    13261 gcaatttttt tgaacatcgt ctgattttct ggtagagcaa ataaataaat cggccattgt
    13321 tctggatttt cgaaagaatc cttcaagtac gtatcaactg cttggtaata gttgacccaa
    13381 tcgatctcta cttcttcatc ttttggattt acgccatgga aagttactcc atctcgggct
    13441 ccgcctcctc cattagaaga gaagttcaaa ccgccacctg tcagttcaga tcccaatgca
    13501 gtaacgacat caaccggtgc cccttctggt agagatactt cttttacttg tttgttgctg
    13561 acttcataca atttcatgga gtcgcggttc aatcccaata aataataaga atagttgaac
    13621 tgcccatttt tgataatagc cagtaaataa ggaagatcac ttacatagta ttgatcgtct
    13681 accgggatac tcaaacgatg gatataggtt tggtcagcag ttataatgac cgctacactc
    13741 gtagttgcac tacgccaaaa cgaaggatct cctaacaaat tttcaatttt ttcttggaac
    13801 ggggaccagt catgttcgga atattttttc tcaaaacgtt tctttgcttc tttcgcaaaa
    13861 tttttgaatt tgatctgatc tttttccaca tcttgatggg cgacatgcgt attcagcatg
    13921 atcgtgacga atggtccttt agcgccttct gaagtcaatt gtgacaataa ttctttatcc
    13981 ttttttgcca taaacgtacc cctcctaaaa aaatcattcc tttgtttcta tctaaagtct
    14041 accacaacac tatttttcca tacaataaaa cgtatctaaa aaaataaaac ggtttctacg
    14101 gttttaaatt tagctatttt tttaagttat cttcataatt tcctcaatta tttagcccca
    14161 gtcttcaact attcttcatg aaatgctgat aaactaagaa aaagaataaa agaggtggat
    14221 cttatgcatt tgattatgat tttcagttta ttaagtatta tcagtttatt tgctttcagc
    14281 gcttcccgct tattagatgc ggaaacacag cctattcctg taaaagtacg taaaaacgac
    14341 cgctaacctt ccataacgtg cgttcttatc ctaaagtttt ttcagaaaca ttgaaactct
    14401 ctcccctctc tgataaaatt ttaatttgta gcgaaacaaa ttaattacaa ggagatcgga
    14461 tatgtccata aaaaaaacac gtctagtcct attattggct agtctcattc tttgccttgc
    14521 ttcttttcta ccagctgttg ctgtgcaagc tgaagatact ttcaaagtaa atgcaaaagc
    14581 agcctttgct gtagatgcgc aaagcggtaa gattctttat gatcaagatg gagaaaaaac
    14641 catggggatc gcttcaatca caaaaatcat cggtctttac atcgtccttg atcaagtaaa
    14701 agaagggaaa ctatcatggg atgataaagt ttcaatttca gattatgcag aaaatttgag
    14761 tgtcacccca gatttatcaa atgttccttt gcataaagaa aacacctaca ccgttaaaga
    14821 attattcgac tctgcaatca tccagtcagc caacgcttca atggttgcct tggcagaaaa
    14881 aatctctggc agcgaagcaa aattcactga acgaatgaaa gaacaattga aagattgggg
    14941 tatcaaagat gcaacgatcg ttaatgcatc aggactgaat aactcttatc ttggcgaaaa
    15001 ccgaccagaa ggtactggag aaaacgacga aaatcaaatg tctgctcaag atgtggctat
    15061 cgttgcccgt catttgatct tggattttcc agaaatactg gatgtatcta gcactacgac
    15121 acaaatgttt ggcgaaaaca cgcaatcacc agtagaaatg gtcaactgga actggatgct
    15181 cccaggattc gtgaattata aagaaggcgt ggacggatta aaaactggta cgactgaact
    15241 tgcaggagcc tgtttcgtcg gtacgatcac taaaaacgat caacgaatca tcactgtcgt
    15301 attgaatgca gacggccatg cggaaaaccc aagtgcccgt ttcaatgaaa cagctcgctt
    15361 aatggattat tgctacgaca attggtcaga aaaagagctt ggaaaagcca atgcaagtat
    15421 ccctagtcta aaaaccattg atgtaaaaga cggaaaagaa tcaacagtgc ccgttgtgct
    15481 taaaagtcct gtaaaagtat gggtacggaa cgatatggat actggaaaat taacaatcac
    15541 accaactctt gacaaaaaac aagtcactga caatgagatc caagcaccta tggataaagg
    15601 aacaaaaatc ggtaccgcaa cgatcacctt ggcagaagat aaattaggtt atcttgaaga
    15661 caacaacgcg ccatccacag aaatcatcac ggataaaacc gtagaaaaag caaatatttt
    15721 cgttattggc tggcgacgcg tcgcagaatt tttcggtaac ttgttttaat tgaacaaaaa
    15781 gaaaaaagca tctttccatg tggaagatgt ttttttgctt tttctagttt aaataacagc
    15841 ttttttcatc tattttcgtt atactgtata agaaaaagga gttgaattta tgaatctaac
    15901 cagagatctg atttttttgg ttctctatct tattggggta ttctccatcg tttattggcg
    15961 aaaacagaaa aaggatcctt ccttgttctt ttacagcagt acatggacgt ttgcggtaat
    16021 cttgacttat tttgtcgtgt tggaaatttt ttattcgacc ttttattttt tgattccctt
    16081 agtgtttttc agtatctttg ccttttccta tttttcagaa aagcgaaggc tgttgaatgg
    16141 tcttttattc aatattttcc tcattagttt tggtatctac ttgtttgtct tgctatacga
    16201 aacacaaaat atttttcttg gcggactgat tgccttgatc acgatcccgt tactgcttgt
    16261 ctttctattc ggcatttatg gattgatcgt ttttcttttt tggaacggtg tcacagtttt
    16321 acgtagagag tcgcattcat tagctaatct tttaacgttg atactagcca tttttcttac
    16381 attgtttctt gtttttgact ttttcttgtt aaaatattta ccacaatgga taaatgcttt
    16441 gtttttctgc atcccattga tcttgatcta tctatttatc gtattctaca actttttgac
    16501 tgtctcattc ttgtatcagt tcaaccgccc tcgatacaac caagacttca tcgttgtgtt
    16561 aggcgccggg ttgatcaatg gagaaacagt ttctcctctt cttgccaagc gaatcaataa
    16621 ggcgattgct ttttattggg cacaaagccg tgcgacatta aatccgccta tcctattaat
    16681 gtcgggtgga cagggagcag acgaaaaagt accagaagca atggcgatga aacaatatgc
    16741 catggaacaa ggaattcctg aaagagatat tcttgtcgaa accaattcga caaccacttt
    16801 ggagaatatg cgctattcaa aggaaatcat ggatcagcaa atgaaaggtc cctatcgcgc
    16861 gatcttcagt tccaacaatt accacatttt cagagctggt ctctatgcac gacaagcgaa
    16921 actgaaggca aatggcattg gggcaaaaac agctttctat tacttgccta acgcgttttt
    16981 aagagaatac atcgccatct tgatgatgaa caaaaaaaga catatgatca tttgcggatt
    17041 gcttttcgca ggttccgcat tcttatcact gatcacttta cttttctaaa aaaacaaggt
    17101 gtgacaaaac atatgtcaca ccttgttttt ttcttttatt ctcttgacga ttggcaagaa
    17161 tagtattcct tttttgacgg ctacttgctg tgcagaataa ataccgctgt ttcctgaaca
    17221 cataaagctg atcaagcaga tcataaagaa gtaagcagca gcttgtgaac caaataattc
    17281 gattcccatc acaaaacagg caatcggtgt atttgtcgca ccagaaaata ccccgataaa
    17341 acctaatcca gcaagaaaag gaacagaaac atggagcaaa ggcgctagta ctgcgccaag
    17401 cgttgcacca atctcaaata gtggtgtcac ttctccccct tggtaccccg cacctaaaga
    17461 caagaccgtg aagaataatt tcccaataaa atcataagca tgtgcctgtc cattaaatga
    17521 ttcctgcagt aacggaagac tcaacccaag gtaacgttgt gtttgcaaaa tcaacgctgc
    17581 ggctacaact actgctccac ctatcgtatt tcgccaaaca ggatgaggaa tccattgcgc
    17641 ataccgcgct tttaaaaaga cgatcgaacg gctgaatacc caaccaatca aaccaaaagc
    17701 aatcccagca acaaaaactt tgaagaacag caacatactc cattcaggaa tcacacccat
    17761 ttggtaatgt agatgagaaa caccatagct ttctgtcatg aaatttgcaa aaagcgcagc
    17821 aaagaagcta ggaaatattg cttctgttcg gactttaccg attgccaaca cttctaatcc
    17881 aaataatgtt ccagctaaag gtgtgccaaa tacagaacta aaacccgcac tgattccact
    17941 gataaccaaa atctcccgtt ctgctttatc caatcggaat aaatgcgcta tattatcagc
    18001 taatgctccc cccatttgaa ctgctgttcc ttcacgacca acagatcccc caaataaatg
    18061 ggtagtgatg gtcccaaaca aggtcaatgg aatgagccgc aaagggatct tctcttctcc
    18121 tccattccct tgatcgatca ctaagttatt cccacgacta gaaagaccgc catgatacgc
    18181 ataaagataa gcaaaaagcg cgccgctgac tggcaataga taaagtagcc aaggatgtgc
    18241 tagtcggata tctgtcacga acgtcaggct atttaagaaa aaagcagaca agctccccat
    18301 gaatactccg agaatcgctg tgaccaccag ccacttcaac atgtacatca aaatacgcac
    18361 tggactcggt aattgttttt ccataaaaaa ttcctcctca aataaaaaaa cgcctactaa
    18421 agaaaggggc tggccccaga ctttagtagg cgtcattagc tatcttacgt tagcatttaa
    18481 aggcgaacac catcacctat tcacttccat taaaagatag catatttttc tgtaaaaaac
    18541 aataaaatta tcgttatttc tttacacgtt cagcaaattc atagaaagga gccaatttcg
    18601 ttaactgttg attacattga tcactatcat gacaaatata attccccttt ttcgtatacg
    18661 tgccatcaga accggctttc gttgtagaaa gaaagagcga gacattcgat gttttctgac
    18721 agatcgcaca gattccctta ttaatcgttg gtgataaagt accgctgatc ccttttaatt
    18781 ttccatcttc gtaataaacc atgaattttt tttgcgtccc tggatcattc caaccgatgt
    18841 acgtatgtgc ttgcaagtcg atttcattcc aagcgggttg tttgagtttt ttcacttttc
    18901 ggaataattt ctcgatttgt ggtttgctcg gctgcataaa cggctggacg atttgcttca
    18961 gctcctccaa tgctcgttct gcttgcgttt ttgtcagttt tacatctaaa actgtcgtta
    19021 aaaacgtatc gatttctgat ggttcgtaac ctaatacatc gcgaatcttt tcagctgcta
    19081 gagcctgaac cgtttgtacc gtttttgagt cattgacaga tgagtacgca tttaataact
    19141 gctctacttc tctttttata aaaaaatatt gatatggttt cattgtttgt tccatgattt
    19201 taaagtcctt tcttctaacc aaagtgcata ctttgtagaa aaaagtgatc ttctgcaaag
    19261 tatgtgttac ctgaagatcc cggactcttt taaataagat acgttttgca tcttatcatc
    19321 acccccttta atgttcattc ttctatgtac atgattcatt cgataaataa aagtaaaccg
    19381 tatcttgagc agatagtcaa ctgcaaacag aaaaaggact gtgacaaaag tcgtgtcaaa
    19441 gtccctttct acaaacaaac ggtgttccag aagtagcttc ttcaaaaaat aagccggaat
    19501 ttcacaaaaa tttgagaagc aattttcgta aattccttct tatttcttga agctgaccca
    19561 cttctgtcac aacctcaata tggtctatta ttggttttac ctgttaaatc gaggattctt
    19621 ttccgaagta acgttgccat ctcttacgca tacttgctga cataggctga gcggcttctt
    19681 tgactgcgca gtatttgtct acgaatgtta cgatatatcc ttctttgtac ttaggcggtg
    19741 caatcgttgc gccccacatg tgcttcaaaa tgatatctcg ctcaagatcc gacaaatcgg
    19801 tgatcttttc tgcattcttt acagcgattc ttggatggat atacgcatgt gtgccttcat
    19861 caaatttcgt cgtacgccaa tcatagtaga acagatcatg caaaagtcca gcacgcgctg
    19921 ttgctttagc attgccaccc catttttttg cgagcagata actatagtaa gaaacactga
    19981 tggaatgctc caaacgagtg gaatgaacat gctgtgtgta attcgctaat tttttcactg
    20041 cttctgtttc taaaagatct tctacataag acatatattc ttcgtcttca cgccattttt
    20101 ctgtcataat tatcgatctg ccaccttttt gaatttcatt ttcttctgaa attgatctaa
    20161 gtataccacc agtgttcgga ttattctagt cgccttggat aaaatagcca aagcttaata
    20221 gttccttaat cataaagaaa aatgataaag aacaatccct gccgcaaccc caacattcaa
    20281 cgattccgca tttcctttca tcgggatata tacgttctga tcagtcaaag acaagatttc
    20341 ctgacttacc ccctgacctt cgttccccat gattattgcg aagttatctg atttttctac
    20401 tttgtctaag gcgtgtgctt cttcatttaa ttctgtgcca tacactgtaa accctttgtc
    20461 tttcattaaa ggaatcactt ctgtcaaatc tttttgcaac acaggcaaat gataattgct
    20521 tccctgcatg ctgcgcagca cctttgtact ataaatatct gccgttcctt tgcctaataa
    20581 aacaccagcc atatcaaatg catctgccgt acggatcatc gtccctacat ttccaggatc
    20641 ttgtacatta tctaataaca gccatcctcc tgaaaaatct ggcgtgcctt cagccgttaa
    20701 cgccatcact gctaagattc cttgtggtgt aggtagatcc gatacagcat ccatgacctc
    20761 atccgaaact agaaaagtag aaatctcttt gtttgcggcc agccagtctc cccattcttt
    20821 catgcctcgc tgtgtcacaa aaagttcttt tatttctgca tcagacgacg cagcttcttc
    20881 aatcagatgg aacccttcca aaagatattc ttccttttct tcccgatatt tctttttatg
    20941 tagttttttt aattctttga ttcttggatt ttttgctgat tggatctctt tcacattcct
    21001 cacctcccca tgattatatc atggaatagg tgcttgagct tgtttcatcc taaaaaaatc
    21061 ggtatcatta atttataaaa taggaaagaa aggtgacgaa catgcgcaaa gttaaaatga
    21121 acgtccaagg acgcgtccaa ggcgtaggat ttcgctacat gaccaagatg gtcgctgatc
    21181 aactaggcgt gactggaacg gtaaaaaacg aagatgacgg ctcagtcacg atcgaagcaa
    21241 tcggcaatga cgacatcatc cagaaattta ttgaagaagt caagaaatct ccgagcccaa
    21301 gtggacgagt gcagtatgtg gatgtccaag aagacccgat gattgaggaa cgaaagaaat
    21361 ttgatgtggt gggataaggt tgtgaaaaag ctggtctgca tcaagcatta aggacaggtt
    21421 gtgaaaaata gctctccata tttttcaaca ggctggactt aatgccgtag atgcaagctt
    21481 ttgaacaccg tcaataaggt tgtgagaaag tcgcttagtt ttgagtagta aggagaattt
    21541 tgtgaaaatg gctttccaca tttttgcata aaatttgact taataccgag aaactgactt
    21601 ttgaacaccg tcgataaggt tgtttttgag acgctttgcc tcaagtatta aagataggta
    21661 gtaaaaaagc tgatctataa cttgcaataa atttgcttaa cccatatttt ccagacagaa
    21721 caaaaaagtt tttagttttt taaataagaa agaaacactt ggaatcactc ttttctttcc
    21781 aagtatttct ttcttgattt tttgtctttt tttcaaaatt tttcgctacg taaaagaacg
    21841 aatatttata tgaaatttct atgaagttga ttgaattcca tgcgcttttt tagtatagtt
    21901 aagtttgtgt aaaaattata gaagaggaag tattctatga ataaatggaa aaactggtta
    21961 ttgggatccg gacttgtcag tatcctgctc tttttatctg gctgtgtgcg gatggattca
    22021 aacggaaacc ctgacacttc gggaatcgtt tatcgagtac tcgtccatcc tatgggccaa
    22081 gcgattacat atctagttga gaatttcaat tggtcttatg gctgggcagt tattgcaatg
    22141 actgtgatcg tccgtatcat catcttgcca ctaggtatta gtcaatcgaa aaaaacaatg
    22201 atccaatctg aaaaaatgca agcgttaaaa ccacaagttg aagcagccca acaaaaattg
    22261 aaagctgcaa caacacgtga agaacaaatg gcagcacaag cagaaatgca gcaagtatac
    22321 cgcgaaaacg gattgagtat gaccggcgga atcggctgtc tgcctctatt gatccaaatg
    22381 ccgatcttct ctgccttgta ctttacggca cgttatacag aaggtattcg ggaatcatct
    22441 ttctacggca tcgatttagg ctcaccaagt atggtacttg ttgtcattgc aggggtcgcc
    22501 tatctgcttc aaggatacat ctcaacgatc ggtattcctg aagaacagaa aaagacgatg
    22561 cgtacgatgc taatcgtctc tcctgctatg atcgtcttca tgtcgatcag tgcgccagcc
    22621 ggtgttacac tttactgggt agtcggtggt gtgttcagct gtctgcaaac attcatcaca
    22681 aacgttatga tgaaaccacg tttgaaagca caagtggcag aagagttgaa acaaaacccg
    22741 ccaaaacaag tcgtcactcc aagaaaagac gtgacagaat cagcaaagcc agctaacaac
    22801 aaacaagcaa caaaacaaat caaacaacca aaaaacagta caaacaacaa aggccgcaac
    22861 gcaggaaagc agcagaagcg gaaataaaaa cataggacaa aaaagatgag agctaagccc
    22921 tcatcttttt tgttactctt cctcttctgc tattccatta attaattcgt tgacagagac
    22981 aatgctttca catcctgcac gaacaaactc gggctctgaa ccaatcattt gtgagttgat
    23041 aaattcaatg accatcggaa gattcatccc agcataaaga gtaatctgtt gtccttccat
    23101 tattagttta gaaatgatat ttgcaggtgt accacctaaa agatcgcata gtaccacaaa
    23161 atcatttaac gaatctgtga cagtgagaaa cttttgtttg tatgtttcag tgccatcttc
    23221 tggtaataaa ggtaacgtgt agatatcctc ttgaggcccc atgatcattt ctgtactttt
    23281 tttcaattcc tcacaaaatt ttccgtgact aatcaatacc aattgtctac tcatttttcg
    23341 ctctccctta tttcgaaatc acacccaatg cagataaagc aacacacaca attaatacga
    23401 taaaaatcgc tcgagtagga gtcatgtttt tctttcctaa taaccaataa acaccaccga
    23461 cgatcccagc aggtaaaatt ttaggtaaga tcatatcgat atagttttgc atattcaatg
    23521 tcacatcgcc aatcgttggt gcccatgaaa atttaacatt gatcattgtc gcaactaatg
    23581 cccctaccat gaatacccct aataaagtgg ctgcgtccgt taatgcagtt aagcgagatt
    23641 gcatagtagt aactaaggaa attccttctt tgtatgcaaa ttcaagttgc ttccaacgaa
    23701 aaaccatgac aacgatctga gcaaaaatcc atataaacac acctatcgga tttccatcag
    23761 ttgccatatt cgccgccaaa gccccaaaaa tcgttggaat caaagcagca aatacggaat
    23821 ctccaatcgc tgcaaaggaa cccatcaatc cagctttcag ccccgatacg gtttcctttg
    23881 aagcaattcc ctctttttct tccattgcaa gatcaatccc agtaatgatt gtattaaaaa
    23941 aattagaagt attaaaaaat tgcgtatgtg ttttcatcat ctcttttaat tctggtgtat
    24001 tgtctccata tatttttctt agttgtggca agatagtata taaatagcca gaaccctgca
    24061 ttctctcata gttccaacct aattgaaaag tgaacaaact tcttcgattg atttgcttaa
    24121 aatcttcttt tgttaatttg taattagatt tcgtcatctt cgatttcccc ctcaacagaa
    24181 tgtgatggct cactagctaa tggttgatgg tctttgtttt gatcattctt ataactgatc
    24241 attgctagtg ctagaccaat caatgctaca gcaagcatcg gcagcgaatt gaaagttgcc
    24301 ggaagatctt taacaacgct tgccacactt gttcctaata attgaacatt agagaataac
    24361 gttgctaata atgccgtgat cgtaaatcct aaaataagat aagatagatg tttttttact
    24421 ggtaaatagc gcagaagaat ggcaaaccca acagctggta aaacagctcc tgctactgaa
    24481 agtccatcgc ctagccattt tagattcccg tttaaaacag aaacaacatt ttcaactaat
    24541 ccaccaccaa atgctaaagc taaaaataca ggaatcatac gagagagcga ccaaggtaaa
    24601 gctcccatta agaaattgcg ttcgattgct tgataattca tgtcttctac gtgacggtca
    24661 atacgatggg caaagtatgt gttagcgaat ctagctaaaa tatccaattg gatcattaag
    24721 cttgctacag gcactgcaat agcagcaatc gcttgttctg gattcattcc aagagaaatc
    24781 gagaaggcag ttgctaaaat cgtcccagag ttggcatcta tttttgatgc gcctccaaac
    24841 gtccccactc ctaaaactgt caactgcata ctgccaccaa taatcaaacc tgcgtttaaa
    24901 tcacccatta ctaaacctgc atataaccct gcaaacactg gcgcactcat tgaagaatag
    24961 atctgtaatt catctaaaat ttgataacct gcatataatg ttaataataa gatctgccac
    25021 cattgaatat ccatggatca ttcctcctat ttgattaaaa gattcataaa gtcttctgct
    25081 ttatcgtttg gtaccatttg agcaattaaa tgtataccaa gctgatctaa ttttttaaat
    25141 acttcgatat ctgcatctac cacattgatt gattttgtaa tggaccgtgt ttcattcgtt
    25201 tgtgacatat tccccacatt tacttctttg ataggaactc ctttttctac taaagataag
    25261 attcgatctg gcttttttgc tacgatcaat actcgttgag agtcatattt gccagctaaa
    25321 atatttgttg ctgctttttc gattggcaaa atgcttaatt ttacccctgc tggagtcgct
    25381 aacttcaatc cacttttttc aattgtgttt gtggctacct catcatccac gaccatgatt
    25441 cgactaatat tcagtttcgt tgtccaaaga tttgctactt atccatgtat caaacgtcca
    25501 tcgattctta caccaataat tgccatcatg cattctcctt atctattttt tctatttatt
    25561 gttcaattaa aactgtgaca tcatcaaata tcccttctgt ttcaaagata acgttttcat
    25621 tttttctttc ttatatttca tttttaagct aagaacaaat tccttcccaa ctaaagaaaa
    25681 cgctttcttt tatatttaag ttcatttgat tttcttaact tgaatgtgtt tcatcaacat
    25741 cgtaactttc atagggtcga tccagccagt tttctcttgt tgcgcgtttg ccataccaca
    25801 agccatagaa aatgcgagaa tctcttcgat tgattgcctt tttgataacg catgggccga
    25861 tcctgcaagg gtcgcgtcac ctgaaccaac aggattaaca actgatattt taggaataat
    25921 gacttcgtaa aaacactgag caacttttgc cacagcacct ctctctccta aagaaacaac
    25981 aacccatggc actccttcaa atattggatg agctaataag gactgaattt tttctaattg
    26041 aatcgaagaa cagatacgtt ggccaatcag ttctcctaat tcttccagat tgggcttgat
    26101 aagtagtggc ttctccttac cttccaatac ttcaagcaaa aatttaccag aagtatctag
    26161 taatatgtct ttcccttttt tatcagctaa agcaaccaat tgcttatagt aatcaagagg
    26221 gcatccttgg ggtaaactac ctgagatcgt cataatatct gatatttcga ggagctgctc
    26281 gaaatgatcg gtaaatgtct gttgttcttt ctttgttatg aaggggcctc gttccaaaag
    26341 ctctgtttgt ctcgaactat gcaggatagc aatagaatcc cttgtctctc ctttaattgg
    26401 aacaaactga tgcatgatcc ctaactgatc tagctggttc tttagatatt caccgtgctg
    26461 gccacctatt aaaccagtag ctatcacctc ttctcctaat aaatttagaa ccctcgccac
    26521 attcactcct tttcctcccg ctgttttatt gactgtttca actcgattga ctttgtcgag
    26581 gtttaattct tcaattgtat acgcgatatc gatggaagga ttcaaggtaa ctgtcgtaat
    26641 catttcatct tcaccttttt gctttttgtt ttattgaacc aaggggtagc ggtttcattt
    26701 attactttat ttaaagtctc gatgttttct ctcccatttg ttcttaacca atgaatagct
    26761 ccgtcttttc cattttcgac gtatgctttg accccatctt tccatgtcgc acgtccacac
    26821 aatacaccat tgaaggtgga acccgattca tgagcaaaaa tcagtgtttg ttgaaataat
    26881 tctgttgaaa cacccccact caaaaaaatg aatggtaatg gagtcgcttc actttgctcc
    26941 ttaaagaagg cagcagcctc ttctttgctg tgaataaatt cacctgtgga atagccattc
    27001 acataattca tattgactgg tacttctact ttcaacacat caactttata ttttggatca
    27061 gaaaattctt tcatcatctc aataactttg tggggcttga ctttcgcata ctctggagaa
    27121 gaactatcgc ttatttgtgc gtcataagaa actaactcca aatagaaggg acgattttct
    27181 ccttcgcact cactacctaa acgttcgatg aacacatgct tcaaatgatt gatttcgggt
    27241 gcttcatcaa catcgtagta aagtaagaat tttactgcat ccgcttgctg ttctttcaat
    27301 ctgagagaag accaatccgc taataaatca ggtagacgac caggcgtagt tgcgtcatag
    27361 ccggttttct cataagctaa caataacccc gtctcttttg ctctgacttt tgctgctggc
    27421 aatccatatt ccggatccaa taaaatagca gaagcatagg gtgtcagctc agctgatact
    27481 agttctttga attcactgat ttggtcttca cttggctctt ttcccaacga tttgatcatt
    27541 ttttttagag caccacgctg atcgatcgct aatgcactaa taatcccatc ttttgttgat
    27601 agtctctcca ttgccctatt tttttcttca ttcatctgtc atttctcctt cggtttcata
    27661 cttatgaata atgacgccct tgactactcg attgaccgtg cctgttggag atggtgtatc
    27721 tggtttatta gctactttga ttgaagtata gagtgcaatg atttgtgcag tcataatcat
    27781 cgctaatgca agataggcat cgggcaattt actcaccgag tcttccaata gcacagtcat
    27841 acctgagaaa tcaatagtac ccggttgcgc aatcgcaatg acattggcag tgacccgatc
    27901 ttcttttatt tcctctaaaa tatctaagtc ataatttcgc gtatatggtt gattgctcac
    27961 aaaacctaca acgagtgtct cgctatttaa aaaagacttt ggtccatgac gaaaccccat
    28021 cgaagaatca aaaattgtag caactttacc tgctgttaat tctaaaattt ttaattgtgc
    28081 ttctcttgtc gcacctgcca aacttcctga acccagataa gcgatccgtt caaaaaaatc
    28141 aggtaataac ttttgaattt cttgatctct tgaaagaaga tcttgaccga ttttaactaa
    28201 ttgttcaaga tatctttctt ttttctccat tgctgtttga tcaaagatcc ataaagcact
    28261 caataacata cacgtaaaac ttcctgtcat agcaaaacct gcatcgtttg ctctctctgg
    28321 catcaataac agataattct gtttatcatc ctgtgcgttt tttgccaaca tcccctcttt
    28381 agcacaagta atcgtcaaat gaaacaatgt ttcaacttgt tcatttgcaa tttgcacagc
    28441 cgctacactt tctggactgt tgccactgcg agcaaatgaa actaataaag tcggttcatt
    28501 tggaaacaaa aattcttttg gtgaagctac aatatctgtc gtgccaaaac tgtggaagat
    28561 aaaaaactga ttgtctccat gttcatttag atagggtaag agcgtatccc caatatattg
    28621 agacgttcct gcacccgtaa aaataacacg tattcttctt ccgtttgctt ctttttttat
    28681 ttgatcaaaa aatagagcta aattttcttg gctttgcatc aatctatcga ttgtttcttt
    28741 ccagagatct ggttgttgtt ttatttcttg tgtcgtgatt gctgcaccta tttgttttaa
    28801 tttgttcttc gatagctcaa acatgttgtt ctccctctca atcattttcg gatatgccga
    28861 attttataat gaaactggtc cgctcttgct acactatctg tatattcgat aatctcattt
    28921 ttcacgttat aggttatcct cgtcagatgt aagacgggag cgccatcagc gattcgtagc
    28981 acaacagcat cttttttttg cacgatactt gcataaaact cttcatcagc taattgaact
    29041 tgttgttcat aatcctgtga aaacacatca tacaacggtt tactttcaag taacggcaaa
    29101 tcaagtccca taaatagttt cgccggtaga taagaacgct caaccatcaa tggctcttca
    29161 tctgccaaac gcaatctttt aagtttaaat acagtttcac ctaaatggat gttcaaattc
    29221 ttagcaattc tcttattagc ttccatttgt ctaaattcta aaatgaccgt cttagggacg
    29281 cgccctattt cgcgcatttc ttctgtaaag ctatatgctc cagctaagtt cgatgactta
    29341 tcagacaaat cagagacata ggtacctttt ccatgtcttc ggtaaatata accttgattt
    29401 tccaattcct gtaaagccag acgtacggtg gtacgactca ccccatagtg ttgacaaagt
    29461 tctctttcag ataacagctt atcatgcgga gtcatctgtg tttcgatacg atccttcaat
    29521 aaatcaacta gttgataata caatgatttt cctttatttg agctctccat aaaaatcacc
    29581 tcttctttac tggttataac cacaacacaa gaatagtgaa ttattaatca tttgtcaaag
    29641 gttttttaga ccaaaaaagc tattataaca gctctttaaa gctttatatc ttgaatagac
    29701 aaagatacct caaaaatacc agttaccaat aaaagaacag aaaaaaagac gaaccacata
    29761 agcgatccgt caaaatggtc taacttatcg agcagcgtga tccacattaa tccctatgat
    29821 attcctacaa ctatcgtttt attacttcca atatcattta caacaactaa aaatagctta
    29881 ttaatgacaa atgttattat tagttttaga taacttttgc agttttatac tttttttcta
    29941 taaaatttga caaacatttt tttaaataac taattatttt ttgaatctgt cactcagaca
    30001 atcctttctc ttacttgtta acataaatag aagttgctgt ttcttctaat agtgtactta
    30061 attctttaat attttgtttt ccttcttcta acatccaact actcgctttt tcttcgcctt
    30121 cggtaacaaa aggtgctact cccttcgccc atgttgctcg cccacataag acaccattga
    30181 atgtcgaacc tgattgtttt gcaaaacgca atgtatcttg aaatagtgca gcgctgactc
    30241 ccgcacttaa aaaaataaac ggttgttcag tcactttcga ttgttcatag aaatacgcgg
    30301 atgcctctgc ttgactataa caagtatctt gcccatatcc ttccacaaat ctcatattca
    30361 ctggtacttc tactttcaat acatccactt gataacgttc ttttgaaaat tctcgcatgg
    30421 cttcaatcac tttatgcggt tttacttttg catagtcaag agaagacgga tcgccaatag
    30481 ttgcatcgta agaaaggagc tctaaaaaga aaggtatgcc ttctgcttcg cattctgaac
    30541 caatccgttc tataactatt tgtttttgca cattaatctc tactggttca tcaacgtcat
    30601 agtacaataa aaatttacaa gcatccgcac ccacttcttt taaccttttc actgaccaac
    30661 tattcagtaa atctggtagt cggcctggca ttttcgcatc atagccggtt ttttcataag
    30721 ctagcaacaa accacattct ttctctcgaa gcgctgctgc aggcagacca tattctggat
    30781 cgagtaaaat agcggaagca tacggagtca ggtactgaga aaccatctgt ttaaattgga
    30841 tgatatcttc tgatgtagct tctttatatt ggttgatcat tttcttcaaa gcaccacgtt
    30901 ggtcgatagc tagcgcgcta ataattccag cttcatccgt caatcgcttc aaacgttcct
    30961 gtttttctat actcattttc ttcatatatc ttcacctatt tctttagtta atattgtagc
    31021 tatttctatt tttgattttg cagctctcaa ctgttctgta acctcttttc gcatcaatga
    31081 tcgtgcaacg agagacaata atttcaaatg agtcgttcct gcttctgaat ctgggataaa
    31141 taacgcaaaa ataaaatcaa ctgactgtct atctaaactg ttccattcaa ttcctttttt
    31201 cagtgtgacg ataatcaaac taggttcatt gattgtttga gacttcgcat gagggatagc
    31261 aaaacctgac attattcctg tagtaccttc tttttctctt tccagaagtt tttgatatac
    31321 ttctttttcg tcatgagcga ttcctaaaca gaatgtttgc tttgctaaaa acttaaatgc
    31381 ttcttcttga ttatctaatg gctgttgtaa aaaaatgttc tcttcatgaa tgattgtcat
    31441 gataaacctc ctgctcttcc ttcttcgata actgtacgat ttgttgcttt attatccctc
    31501 ttcttgtctt tatcagttac tcttttcttt tggatcaaac ctagtatcac tccaccaacg
    31561 atcgaaccaa taagaatcgc tgtaacccat tggatttttc ccgtcactac aggtaacact
    31621 aaaaaaccgc catgtggggc tggtacttgg acaccaaaca gataggtcaa gacagcagca
    31681 attgatgagc ctaacatcat cgttggtaat actcggatcg ggtctttcgc agcaaacgga
    31741 atagctcctt ccgtaatatg agttgatcct aaaataaaat taaccaaacc tgcattacga
    31801 tcattagtat caaaatattt accaaacaat aaagtagcaa aaccagtaat caacggtggt
    31861 gcaatgcaag ctgctgacgc accagccata aaagtcgtgt ttccttgtgt caaaagagct
    31921 gttcctgtta catatgccgc cttattaacc ggtcctccca tatcaaacgc acacatacag
    31981 ccaacaatca cgccaagaac aagtggattc gaatattcaa atccagctaa aaagctcatc
    32041 attccttcat ttatagcctt cattggacct gccagcaaag acatcacgat gccaataaat
    32101 gctacaccaa taactggata taagacgatt gccttcaagc catctagttg tttaggtaaa
    32161 attatcagta gcttttgcaa aaataagata aaataacctg ctaagaaccc agctaaaata
    32221 cctcctaaaa atccagtacc gccattcatg gctacgattc caccaacaaa tccaacgact
    32281 aaccctggac gtttcgcgat cccttctgca atataagctg ctaaaactgg aaccatcatt
    32341 cccattgctg catcgtcaac tgcttttacc attgccgctg tagcattgta ttgtgcatga
    32401 tctggatcag aagaatagat tccccaaacg gcaaatgaaa tagcaatcaa tactccgcca
    32461 gctaccacga aaggcaacat atgagagaca ccgttcatca aatttttata gatgctacga
    32521 ccaaaattag caccacttat cgcttctggt tctaaagtat cagcagcttc attatctgct
    32581 aagacagtac cttttcctgc caatgcttcg tcaatcagcc gttgtgcatc cttgattcct
    32641 gtactgacag aaacatcaat gactcgtttt cccacaaatc tttctgaatg gacatctttg
    32701 tctgcggcaa taatgacagc atctgcctgt ttgatttctt cagccgttaa ttcattctcg
    32761 atcccaattt gtccatgggt ctccactttg atcgtgatgc cttttttcct agctgcttgc
    32821 tctaatgcct cttgcgccat gtaggtgtgc gcaattcctg tcggacaacc ggttgctgca
    32881 attagttgat attttcccat ctttcgaacc tctcttcctt gattttgatt tgtttactta
    32941 attcctccac atccaaaaaa tcagtcagtc ctttacgaaa agcagtagag ctgcctgctg
    33001 ctatgctttt acgtaacgtt tcatcaagcg atcgtcgatt catgtatcct gctaaaaaag
    33061 tgcctaacat ggcatcacct gcacatgctg tattgacaac ttttcctttt ggcgagtttc
    33121 ctcgaatcac cctgtctttc gtaaaaagaa tcgctccttt ctcaccgagg gataacaaaa
    33181 cattttctgc gcctgactct actagtcgtt gtccataaac aaagtaatct tcatctgtaa
    33241 ccatttttcg tccgaaccaa gaagaaagtt cttcctcatt tggtttcagc aaaaacggtc
    33301 gatagggtaa acaatccatg acttcttgat cactactatc aataatcaaa caaatccgac
    33361 tgatttctat taaaaccttt ggagacagcc ctcttggtaa actcccagaa acacaaagat
    33421 aatcccctgc ttgtaatgct cttatttgat ttaaaaaatt atgaacagct gtctgcggta
    33481 tttcaggtcc ttgattcact aatttgtatt cttctcccgt ttgattgact tgtgtaaata
    33541 cattgatacg cgtcatacca ggcacttcaa taaactctgt ttggatttgt ttctgctgta
    33601 aatagtcttc tatatacttt cctgtgaacc cagcagaaaa acctaatgcc gtacttggga
    33661 aatctagcat ctttaatact agtgacacat tcaccccttt tccgtttgcc tgaatgtcat
    33721 cctcttttgt gcggtttacc ataaaaggat gcatctcatc tgtttcaata aatagatcaa
    33781 ttgccaaatt catcgtgcat gtgtagatag acataaccaa cgacctcctt gattctatta
    33841 tgaaatacgc gaaatagaaa atgttttctt aatcgtccca acacaaagaa aacctttaca
    33901 tttataaact cgtcgtgctt tttttaacta acttttggtg aaagaaggaa agaatatgaa
    33961 tcacaaatta agtgaaacag agcagtacct ctggaacttt atcgaacacc tcatcctaga
    34021 gatccctaac tattccatcg tgaaactaag tgaacaagca aatgtctcaa cagccaccat
    34081 tgtgcggaca atgaaaaaga aaggctatga agggtttact tcgtttaagc atcatctaaa
    34141 agaaggagaa aacaagaaca tcaatttttc atttttagat aaagtagaca aaggaatccg
    34201 ccgagccatt ctaaaaaatg aacaagaagt ggtacgtaca atcaatatgt tggaaatcgg
    34261 gaacattgaa gatgcaatac aaagaatcaa atttgctgac cgggtttttg tctttgcccg
    34321 aggattttca gaaatgattg gccaagaaat gctggtaaaa cttcaattaa cgggaaaaaa
    34381 ttgtcagatg catactgatc cagaaattat caaaagcatc agtcggaaac taactaagaa
    34441 agacagcgtt atttttgttt ctttgaacgg tgagaaaaca aataaaaaca tcaaaaataa
    34501 gatttatgtc tttatttttc aattttttaa at
//
LOCUS       DADQDV010000028        33263 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.028, whole genome shotgun sequence.
ACCESSION   DADQDV010000028 DADQDV010000000
VERSION     DADQDV010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 33263)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33263)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33263
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.028"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(41..229)
                     /locus_tag="J8S10_001386"
     CDS             complement(41..229)
                     /locus_tag="J8S10_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HAZ9629974.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            499..861
                     /locus_tag="J8S10_001387"
     CDS             499..861
                     /locus_tag="J8S10_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAZ9629975.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            913..2595
                     /locus_tag="J8S10_001388"
     CDS             913..2595
                     /locus_tag="J8S10_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HAZ9629976.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKETPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            2712..4748
                     /gene="recG"
                     /locus_tag="J8S10_001389"
     CDS             2712..4748
                     /gene="recG"
                     /locus_tag="J8S10_001389"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HAZ9629977.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKEFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LLTGSTKAKERRELLEKLEQGEINIVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            4797..5798
                     /gene="plsX"
                     /locus_tag="J8S10_001390"
     CDS             4797..5798
                     /gene="plsX"
                     /locus_tag="J8S10_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HAZ9629978.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            5920..6162
                     /gene="acpP"
                     /locus_tag="J8S10_001391"
     CDS             5920..6162
                     /gene="acpP"
                     /locus_tag="J8S10_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HAZ9629979.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            6430..7434
                     /locus_tag="J8S10_001392"
     CDS             6430..7434
                     /locus_tag="J8S10_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9629980.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            7435..8379
                     /locus_tag="J8S10_001393"
     CDS             7435..8379
                     /locus_tag="J8S10_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9629981.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            8379..9341
                     /locus_tag="J8S10_001394"
     CDS             8379..9341
                     /locus_tag="J8S10_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9629982.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            9368..10282
                     /locus_tag="J8S10_001395"
     CDS             9368..10282
                     /locus_tag="J8S10_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9629983.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            10308..12089
                     /locus_tag="J8S10_001396"
     CDS             10308..12089
                     /locus_tag="J8S10_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HAZ9629984.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            12437..13123
                     /locus_tag="J8S10_001397"
     CDS             12437..13123
                     /locus_tag="J8S10_001397"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HAZ9629985.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            13143..16724
                     /gene="smc"
                     /locus_tag="J8S10_001398"
     CDS             13143..16724
                     /gene="smc"
                     /locus_tag="J8S10_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HAZ9629986.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIEAALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            16733..17542
                     /locus_tag="J8S10_001399"
     CDS             16733..17542
                     /locus_tag="J8S10_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAZ9629987.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            17553..18551
                     /gene="ftsY"
                     /locus_tag="J8S10_001400"
     CDS             17553..18551
                     /gene="ftsY"
                     /locus_tag="J8S10_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HAZ9629988.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            18738..21005
                     /gene="gshAB"
                     /locus_tag="J8S10_001401"
     CDS             18738..21005
                     /gene="gshAB"
                     /locus_tag="J8S10_001401"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HAZ9629989.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKKYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(21094..21546)
                     /locus_tag="J8S10_001402"
     CDS             complement(21094..21546)
                     /locus_tag="J8S10_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HAZ9629990.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            21696..22646
                     /locus_tag="J8S10_001403"
     CDS             21696..22646
                     /locus_tag="J8S10_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HAZ9629991.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            22639..23598
                     /locus_tag="J8S10_001404"
     CDS             22639..23598
                     /locus_tag="J8S10_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HAZ9629992.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            23595..24350
                     /locus_tag="J8S10_001405"
     CDS             23595..24350
                     /locus_tag="J8S10_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAZ9629993.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            24373..25326
                     /locus_tag="J8S10_001406"
     CDS             24373..25326
                     /locus_tag="J8S10_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HAZ9629994.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(25970..26266)
                     /locus_tag="J8S10_001407"
     CDS             complement(25970..26266)
                     /locus_tag="J8S10_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HAZ9629995.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            26621..26977
                     /locus_tag="J8S10_001408"
     CDS             26621..26977
                     /locus_tag="J8S10_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HAZ9629996.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            26987..27886
                     /locus_tag="J8S10_001409"
     CDS             26987..27886
                     /locus_tag="J8S10_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HAZ9629997.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            28403..29134
                     /locus_tag="J8S10_001410"
     CDS             28403..29134
                     /locus_tag="J8S10_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HAZ9629998.1"
                     /translation="MMKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEA
                     GDEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYA
                     AADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAV
                     SLVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSV
                     PGKSVKLAQQYSTKLVWTLEDTPNN"
     gene            29279..31306
                     /locus_tag="J8S10_001411"
     CDS             29279..31306
                     /locus_tag="J8S10_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lectin"
                     /protein_id="HAZ9629999.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGRSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRINIPVENQRIGTFEGKLSWILADVPGN"
     gene            31414..32511
                     /locus_tag="J8S10_001412"
     CDS             31414..32511
                     /locus_tag="J8S10_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HAZ9630000.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
     gene            32818..>33263
                     /locus_tag="J8S10_001413"
     CDS             32818..>33263
                     /locus_tag="J8S10_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAZ9630001.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRK"
BASE COUNT        11138 a         5762 c         7123 g         9240 t
ORIGIN      
        1 aaaaaccgtt cactatctga acggtccaag tatcattcaa ttaaacgcgt tcaacttttc
       61 ctgatttcaa agcacgagtt gacacccaaa cttttttagg ttttccgtcg accataacgc
      121 gaactttttg taagttaggt ttaacagtac gttttgttga gttcatagcg tgtgaacggt
      181 tgtttccact ttttgtcttg cgacctgtaa agtaacaaac ttttgccatg gtaatttcct
      241 cctttgcctt gatttggagc aatagaataa ttcagctcat accagactaa catatcatat
      301 agaatggaaa tttgcaagta cattttcata gatacaattg acaattgaga agaataattg
      361 taaattaaac aaggttatac ctgaaatttt gcaaggtttt tgagtacttt gggtaactgc
      421 cttttatttc aagttgcgct atgataaaat atgatagaag aaaaatggga gttttttacc
      481 cgttaaggag gctcattcat ggctgtaaaa attcaaacgt cagctggaac cattgaaatt
      541 accaatgatg taattgcaac agttgttggt ggcgccgcga cagatgtgtt cggtgttgta
      601 ggaatggcca gcaaaaatca aattaaagat aatattactg agattttgcg taaagaaaat
      661 tactcaagag gagtagttgt ccgccaagaa gataatggta ttgctgtaga tgtttatacg
      721 attatcagct atggtacgaa aatctctgaa gtttcccgca acgtccaaga aaaagtgaaa
      781 tacaatctag aggcattatt aggcgtaact gccaattcag ttaatgtctt tgtacaaggt
      841 gttcgtgtac tgccagacta ggcaggagac tggctggtaa ctcagcagtc gatctgaagg
      901 aggattatct aggtgagtgt aacagaaata agtgcaagcc agttccagga aatggtccag
      961 gcaggtgcga atcgtctgca agtaaatgca gaatacgtca attcattaaa tgtattccct
     1021 gtgccagatg gcgatacggg aacaaatatg aatctatcta tgactagtgg agctaaggca
     1081 gtagtagatt caacctcaga aaaagtagga gaattagcag caatgctttc aaaaggattg
     1141 ctgatgggtg cgcgcggaaa ttccggcgtt attttgtctc aattgtttcg tggattttct
     1201 aagcaaattc cagatgttgt ctcattaaat gcttccgatc ttgctgcagc cttcactcat
     1261 ggagttgaaa ctgcgtataa agcagtaatg aaaccagtag aaggaacgat tttgacagta
     1321 gctagagaag cagcgaaagc tggagaaaag aaagcaaaaa gtactgatga tgtcgttgaa
     1381 gtaatgacag ctgttgtaaa aggggcaaag cgtgctttag ctaaaactcc agacttgctt
     1441 ccagtcctaa aagaagtcgg tgtcgtagac agtggagggc aaggactgct gtttgtttat
     1501 gagggctttt taagtgcatt gaatggagaa ttccaagcgg atgaaacata tgaaccttct
     1561 ccagcagaaa tggatgatat ggtcaatgca gaacatcatc gcagtgtcca aggtcaaatg
     1621 gcgacagaag atatccattt tggttactgt acagaaatca tggtaaaaat cggagaagga
     1681 cctacagtcg atagtacatt cgattacgaa gaattccgta actatttaga tggtatagga
     1741 gattctttac ttgtggtcaa tgatgacgag atcatcaaag tccacgtgca tacagaaaac
     1801 ccaggagaag tcttgaatta tggacaaaaa ttcggttcat tagtcaaaat caaagtcgac
     1861 aacatgcgct tgcagcatga gacgattttg gaacacgatg aagaagtgaa cgagtttgcg
     1921 aaaaaagaaa caccacgtat cccgtatggt atcgtagcga tcgctgctgg taaaggcgtc
     1981 caagagctgt ttgaaagttt aggcgctaat tatgttatca gtggtgggca aacaatgaat
     2041 ccaagtacgg aagacattgt taaagcgatt caagaagtaa acgcagataa agtgattgtc
     2101 ttgccaaaca ataagaacat cttcatggca gctgatcaag cagcagaagt agcagatatc
     2161 ccagtagcag ttgttccttc aagaacgatt tcccaaggat tgacagctat gctttcattc
     2221 aatgatcaag cttctttaga agaaaacaaa gaaacgatga cagaaatgtt gtctagcgtt
     2281 gtgagcggtc aagtcactca cgcgatcaga gatacctcaa ttgacggtgt agagatcaaa
     2341 gaaggagact ttttgggcat gatcgatgga aaaatcctga tctctaaccc agatatcaca
     2401 gcaacagcgt taagtacact agaacaaatg atcaatgagg acacagagat cgtaacgatc
     2461 ttggcaggtg atgaaggaac agttgaacaa gcaaatgaat ttgctgagaa actaacagaa
     2521 aaacatcctg atttggaaat cgagatccac caaggagatc agcctgtcta tccttatcta
     2581 ttttctgctg aataatttct gtgtcagaat atctttctaa cacagtattc attcataaaa
     2641 ggccttcggt tagtgatcag gtatgatcgc tgaccaagtc ctttttttgt taagggaggg
     2701 aggaaaaatt tatgcgttct ttagatgatc caatcactat gctggcagga gtcggagaaa
     2761 aaagagcagc tagtcttgcc agcttgggca tccaaacgat tgaagactta ctgacttatt
     2821 atcctttccg ctacgaagat attcaggaaa gaaatctaaa cgagatccaa gatcaagaaa
     2881 aggttacttt gaaaggaatc gtagtctcgc ctcctgtgat gaatcgattt ggttataaaa
     2941 aaagccgatt gcaatttcgt atgatgcaag aacatgatgt gttcaacgtt tcttttttta
     3001 atcaacctta tctaaaagaa aaagtcattt tatcggagga aatcgccgta tacggtaaat
     3061 gggatgcaaa gcgtaaagca ttgaacggga tgaagatttt aggttctcaa acaatggatg
     3121 acttttcgcc gatatatcac gtcaacaaat caattcgtca aacgacatta gttgatctaa
     3181 tcaaaaaagg gtttcaagaa tacggcacat tgattgaaga aaatctgcca aacaaccttg
     3241 tggagaaata tcgactgctt gaccgagctt ctgctgtaag aagtatgcat tttccaaaag
     3301 accacgaaga aaaccatcaa gccaaacgac gtgtcgtttt tgaagagttc tttttatttc
     3361 aaatgcgtct tcaaggattg aaaaaagcag aaaaagcaga aacgaatggt ttggagatcc
     3421 tttatgatgt ccaaaaattg aaagaattta ctcaaaagct accttttgaa ctgacaaatg
     3481 cacaaaaacg tgtaacgaat gaaatctgtc gggatcttcg cagtccgcag catatgcagc
     3541 gacttttgca gggagatgta ggtagcggaa aaacagtggt tgccgcgatt gcgttatacg
     3601 ctaccgttac agcaggtttc caaggtgcgt tgatggtgcc tacagaaatc ttggcacaac
     3661 aacatatgga aagcttgcaa cagctgtttg atcccaatga agtaaccatc gcattgctta
     3721 cggggtcaac gaaagcaaaa gaacgtcgtg agctccttga aaaactagag caaggggaaa
     3781 ttaacatcgt gatcggcaca catgcattga tccaagatgg agtcgaattt cagaatttag
     3841 gtctagttat tacggatgag cagcaccgtt ttggcgtgaa ccagcggaaa gtacttcgtg
     3901 aaaaaggctg gcgaccagat gtcttattta tgacagcgac tccgattcct agaacattag
     3961 ctattacagc atatggtgag atggatgtat ctatcattga tgaacttcca gctggacgta
     4021 tcccgatcga aacacgctgg gtaagaacac ctcaattgga cagtgtactg gattggacga
     4081 aaaaagaact ggcaagagga catcaaatgt atgtcatctg tccgctgatt gaagaatcag
     4141 aagcattaga tgtaaaaaat gcagtggaaa tctatgaaaa acttcgtgaa ctatttgcac
     4201 caaaatatga agttggcttg ttacatggta aaatgaagaa tcaggaaaaa gaagtaatca
     4261 tggaagcctt caaagacaac cagatgcaga tattagtttc gactactgta attgaagtag
     4321 gggtaaacgt gccgaacgcg accgtcatgc tgatcatgga tgcggatcga tttggattgg
     4381 cacagctgca tcaacttcgt ggacgtgttg gacgcggaag tgatgcttcc tactgtatct
     4441 tagttgctaa tcctaaaaat gaactaggtg tggaacggat gaaaatcatg acagagacca
     4501 ccaatggttt tgtactaagc gaaaaagatc tggaattacg tggtcctggt gaagtatttg
     4561 gcttccgtca atctggtctg cctcaatttg cgattgctga cttggtgacg gatggaaatg
     4621 ttttggaggt agccagagaa gaggctgcag ccctttggca gataaaggat tggcagatgc
     4681 ttcctgagta tcagccttta gcgcaaagcc tccaaataga aaatcaggat aatcgttatt
     4741 tcgattagca gactgtgcta tactttatac tgatgacgga aaaaggagtg gaaacaatga
     4801 aaattgccgt agatgcaatg ggcggagatc acgcacctca agcaattgta gaaggcgtgg
     4861 ctttagcgca gcaagatttt ccagaagtag aattcttact ttacggaaaa gaagcagaaa
     4921 tcaagaaata cttaacaaat gaaaaaaaca tcacgattat ccatacagac gaaaaaatca
     4981 atagtgatga tgagccagta aaagcaattc gacgaaaaaa gactgcatca atggtccttg
     5041 ctgcacaagc agtgaaaaac ggtgaagcag atgctgtatt ttcagcaggg aatacaggcg
     5101 cgctactagc agcagggttg ttcatcgtag gacgtatcaa aaatatcgaa cgccctggct
     5161 tgatgtctac cttgccagta gtagggaaag aaggtgccgg tttcgatatg ctggatcttg
     5221 gcgctaacgc agaaaacaaa ccagaacatt tgttgcaata cggtatttta ggttcttttt
     5281 atgcacgtaa agtccgaggt atcggacgtc ctcgtgtcgc actcttaaac aacggaacag
     5341 aagcaacaaa aggtagtgaa gtgacgaaaa aagcctatga actccttcag aatgaaacaa
     5401 gcttgaattt tattggaaac gtagaagctc gtgagctact caatggtgtg gctgatgtag
     5461 tggtcacaga tggatttaca ggcaacgctg ttttgaaatc tattgaagga acagcaatga
     5521 atatgatgaa tctattaaaa tctgctattc taaatgaagg gatcaaagga aaaatgggcg
     5581 ctatgctttt aaaagacggc ttacgttctt tgaaagcaga aatggattat tccaaacatg
     5641 gcggtgccgt tttgtttggc ttgaaagcac cagtcattaa aactcatgga gcaacaggcc
     5701 ccgatgctgt tcgctatacg atccgccaaa tccacacaat gcttgagaca gatgtagttg
     5761 gacaattagt cgaacaattt gaaaaaagcg aagaatagta tttggatatc tgaagcaatc
     5821 cgttccattg aaaaaaaggt ggacattcct gaaaaatgcc agtaaaatta gccatggtgt
     5881 aggtaattga caagtgtatg attcttggag gtgaaaaagt tgactcgcga agaagtattt
     5941 aacaaagtag cgaaaattat ttcaaatcat tttgagatag ataccgataa agtgacggat
     6001 gaattgaaca tcaaagatga tttaaaagct gattcaatta gtattatgga attcgtttta
     6061 gagcttgaag atgaattcgg tacggaaatt tcagatgaag acgctgaaca aattgaaaca
     6121 gtcggtggcg cagtagatta tatcagcagc catcttaaat aatttcaaat aaaagcaaag
     6181 aaggataaaa agctgcatac agctttttat ccttcttttt ttaatctttt tgacacgtaa
     6241 aagtcatttt tctgataatt ctggcgataa acagaaatta tgttgcaaag taaagcgatt
     6301 ttctatataa ttattaataa ttcattacac aaagataaga ataacctttg ttataaaacg
     6361 ctttattctg tgtaatgtcc ttttttatta agaaaaactt ccatttagga agcagagagg
     6421 ggtattcgat tgtccgataa ccaattatta gaagttcaga acctacatac aggattccga
     6481 ctcaaagatg actattacga tgcagtagat gacgtttcat ttactttaga caaaaacgag
     6541 attttagcaa tcgttgggga atctgggtgc gggaaaagta ccttggctac tacgattatg
     6601 ggattacttg atcctaataa cacaaaaatt acaggtgaga ttttatataa cgatctgaat
     6661 ttaatcgacc tgaacgaaac gctctataat aaaatccgcg gaaatgatat cggaatgatt
     6721 ttccaagatc cgttgtctgc attaaatcct ctcatgagaa tcgaagacca gatcaaagaa
     6781 ggactttcct atcacacaaa gatgaatgca gaacagcgtc aagctcgtgc actagaattg
     6841 ctagaacaag tagggattcc taatcctgcg agagttggac gccaatatcc ccatgaacta
     6901 tcaggcggta tgagacaacg tgtcatcatc gcaatcgcaa tcgcctgcaa acctccaatc
     6961 gtcattgcag atgaaccgac gacagcccta gatgtaacca tccaagcaca gattcttgat
     7021 ttactgaaag accttcagga agaaacaaaa acagggatca tcttgatcac tcatgactta
     7081 ggagtcgtag cagaaatggc tgatcgagtg gcagtgatgt atggcggaca gttcgttgaa
     7141 gtagcaggtg taaaagaact gtttgatcat cctaagcatc cttatacacg ctctttactg
     7201 aactctatac cacaagaagg aaatcatgat gcagaactcc atgtgatcga aggtgtcgtt
     7261 ccttctctga aaaacatgcc tcgtaaaggt tgtcggtttg caccacgtat tccatggata
     7321 ccagcaagcg atcatgaaga agagcctatc cttcatgaag tcgcaccgaa ccacttggta
     7381 cgttgctcct gctataagca tttccacttt agagacgaaa aaggagaggt gtagatgaca
     7441 gaattaatca caatcaaaga cctgaaagtt cattacccta ttcgcagtgg attcttcaat
     7501 cgagtaacgg atcatgtata tgctgtagat ggtgtggatt ttattatcga aaaaggaaag
     7561 acatatggtt tagtgggaga gtctggctct ggaaaatcta ctacgggaaa agccgttgtg
     7621 ggattagaaa aggtaacagc cggacaaatc atgtatgaag gaaaagatgt aacgaagcga
     7681 agcaaccgca aaaaaatggg ttataacaag gatgtgcaga tgatcttcca agattcaatg
     7741 tccagtttga atcctaaaaa gcgagtgttg gatatcattg ctgaacccat ccgaaatttt
     7801 gaacggttaa gcgatcaaga agaaaagaaa aaggtaaaag gactgctaga tatcgttggg
     7861 atgccggaag atgcgctata taaatatcct catgaatttt caggcggaca acgtcaacgt
     7921 ctaggagtag cccgtgctgt tgctaccaat ccaaaactga tcgtagccga tgaacctgta
     7981 tctgctctgg atctatctgt tcaagcgcaa gtattgaatt tcatgaaacg aatccagcaa
     8041 gaatacggcc tcagctattt attcatttca catgatttag gtgtagtaaa acacatgtgc
     8101 gacaatatcg caattatgta caaaggtcga tttgtagaaa tcggtacaag agaagacatt
     8161 tataatgacc cgcgacatat ctatacgaaa cgtctgcttt cagctattcc gcaaatcgat
     8221 gtagaaaata gggaaagcca caaagaaaat cgacgaagag tagaacaaga gtatatccaa
     8281 aaccaaaaag aatactatga tgcgactggt cgagtctacg atttgcgtac gatcacaact
     8341 acacacaaag tggcgttgaa agatggaggt gcaagctaat gtggaaaacg attctgcgac
     8401 gtgttttatt gatgatcccg caagttatta ttttaagtgt tctgatcttc ttattagccc
     8461 aagcgatgcc gggggatcca tttaccggtt tgatcaatcc aaatcaggat ccggcagtga
     8521 tcgaacagat gcgacaagca gctggcttga atgacccatg gtatgtccag tacttccgtt
     8581 ggatcggaaa tgctttgcaa ggcgattttg gtcaaagttt cttatacaaa cgctctgttg
     8641 ctgacttgat cggcgaacgg atcatcaaca ctttatatct atcgatcttg acagttgtcc
     8701 ttacttattt gattgctgtg cctctgggga tgcttgctgg ccggtatcaa aattcaatct
     8761 tggataagat tgtcgtaatc tacaacttct ttagttttgc tgttccttta tttatcttcg
     8821 gcttgatcat gctatttgtt tttggttatc gtttaggctg gttcccaaca agtggatcac
     8881 aaacactagg tttgcaaggt ggatttatca ctcaatggat agaccgtttg aaatatattc
     8941 tgttaccatc aattacccaa gcatttttgg cgactgccgt cacaatccaa tatctgcgaa
     9001 gtgaagtaat cgattcgaaa tcgctcgatt ttgtcagaac agcccgttcc aaaggggtac
     9061 cgacgaataa agtattcagt cgacatattt tccgaaatgc agcgttgccg atggcttctc
     9121 aaatggggta tgaaatcact tcgttgattg ctggttctgt agttatcgaa aagatttttg
     9181 gttatccggg agtcggaaaa ctatttattg attccatcgg ccaacgggac tataccgtga
     9241 tcacatcctt agtattgatt ttaggaatcg cgacgctagt ggggacatta ctttcagata
     9301 tcatcatgag tatcgttgac ccgcgtattc ggattcaata aaaccaatca gaaaggagaa
     9361 tggatcgatg agtgaaaaaa acaatacagc agttcaagaa agtattcctc ctatggggat
     9421 acgaatgatt gctcgagaat ttaaaaaaga taaaattgct attttttcat taggtttgct
     9481 agtggtttta ttattagtga tctttatcgg tgcgatgctg accgatcaag acaaagtgat
     9541 gtatgttagt atcttcgaca aatacgctgc accaggaaca gtttcgacac aaggacaaaa
     9601 gttcattctg ggagcagatg aaggcggacg tgatgtatta ggacaattga tcataggtgc
     9661 tagaaactct gttacgatcg gatttgcgat cacgatcctt acttcgatca tcggggttgg
     9721 attagggatc atctctggct actacggagg gatcattgac aacatcttga tgcggatcgt
     9781 tgattttatc atgattctac cgatcatgct gatcattatc gtcttcgtat cgattatttc
     9841 cagatacaat gtctggtcct ttatattcat catgagtgca ttttattggg tagctaaagc
     9901 ccgattattc cgaagcaaga cattatctga agcaagaaga gattatgtca gtgcctcaaa
     9961 aacaatggga accaatgatt ttaaaatcat gttccgcgaa atcatgccga atctaagttc
    10021 attaatcatt actaatttga cgatgaactt tgcggcaaac atcggtatcg agacaacttt
    10081 gactttctta ggtttcggct tgccggcaaa tgtacctagt ttaggtacat tgatcggtta
    10141 tgcaagtaac ggagaagtct tagtgaatcg gcaatggatc tggttacccg catcaatcct
    10201 tattttagtt ttgatgttga gtatcaatta tgttggacaa gcattcaagc gttctgcaga
    10261 tgcgcgccaa cggttaggct agtatagaag cgaaggggga aataggaatg aagaaaacga
    10321 tttttggatt tgcagcgctg atgtctgctg tcgttcttgc agcatgcggg ggcggaggta
    10381 cagatacctc tggaaacaac tctggaggca acggcaataa caaagaggaa ttaacttttc
    10441 caattgcaac aaaaaataat gatgatgcaa tcgaagacgg cgaattagaa gctgcggtcg
    10501 caacggacag tcagtttaaa ggattgttcc agtgggagtt ttaccaagat tcatatgatg
    10561 cagcttttat ggctccttct catgaaccgc tatttgcaaa cgatgacgat ttcagaatca
    10621 cagacgacgg agctgcaacg cttgatctag atgaagatac gaaaaaagcg acaatcaaag
    10681 taaaagacaa cgtcaaatgg tcagatggtg aagatgtaac ggcggacgat gtgattttcc
    10741 cttacgaaat cattgggaat aaagattaca ctggtatccg ttatgacgac actttccgta
    10801 acatcgtagg tatggaagaa tatcatgatg gaagtgccga cacaatctcc ggaatcaaaa
    10861 aaatagacga caaaacagtt gaaatcgaat ataaagaagt aaacccaagc atgcttcaat
    10921 cgggtggtgg tatctggtca tatgcagcac caaaacatac gttagaaggt gtagcaatca
    10981 aagatatgga atcaagcgat caagtacgta aaaatccagt gacttttggc ccttattaca
    11041 tgagtaatat cgttgcagga gaatcagtag aatacttgcc aaacgagcac tactggaatg
    11101 gtacgcctaa attgaaaaag atcacgatga aatctgtacc gatggcaagt gcaactgaag
    11161 cattgaactc taaattatat gatatgattt tccaaatgcc aacagatact tacgatacct
    11221 ataaagaaat tgctggctat acaaacttag gccgtgaaca aacttcttat acttatctag
    11281 gattcaagtt aggtaaatgg aatgcagata caaagagtgt ggaatacaat ccagattcaa
    11341 aaatggctga taaatcatta cgtcaagcaa tgggctatgc attagataat aatgcagtag
    11401 gtgaacgttt ctatgcaggt ttgagaagca atgcgacttc attgattcct ccagtattcc
    11461 agtcatacca tgatgatgag atgaaaggat tcacacaaga tctagacaaa gcgaaaaaac
    11521 tattagatga tgctggctac aaagatgtgg atgacgatgg tttaagagaa gacaaagatg
    11581 gaaataaact aacaatcaac tttgcttcga tgtccggtgg ggaaacagcg caaccattgg
    11641 cagattacta tatccaacaa tggaaagaaa ttggtttgga tgtccaatac acaacaggtc
    11701 gtctgatcga attcaattct ttctatgata aattagaaaa cgatgatcct gaaattgatg
    11761 tttaccaagc tgcttggaat acaggaactg atccaaatcc aagtggacta tggggaccaa
    11821 atgctgcgtt caactacact cgttatgaat cagaagaaaa tacaaaattg atcaacgata
    11881 tcagttcaag caaagcattt gatgaagagt accaaaaaga agcatatcaa aaatggcaac
    11941 aatatgcatt tgaagaagca tttgcgattc caacgttgtt ccgtaatgaa gtattgccag
    12001 tcaacgaccg tgtcaaagac tgggattggt cttatgatgt accaaaccca tgggcaaatg
    12061 tttctgttac agcagattca cgttcataat cactaaaaat gaccgaaaaa gggcgatgtc
    12121 ctttttcggt tttttgatat ttttctgttt atttctctaa tattcaggtc aaggcgctga
    12181 tttcatgact tctccaataa acggtgttca aagtccagtt tctcggtatt aagtcaaatt
    12241 tatgcaaaaa tatggaaagc cattttcaca aaattttttc ttcatactcg aaactaaacg
    12301 aatttttcac aacttctcgt caatcactag gattattaaa gctttactta ccttttgacc
    12361 gaaccatttc aaatttgaca aaaaaccagt ataataagga agtatcgaaa aaatatccat
    12421 aaaaggaatg tggaaaatgg acaaccagct gacaaaagaa ctaaaagaaa actataacat
    12481 cgtttttcac gatctaaatt tgcttgaaca agcttttacc cattcatcct atgtgaatga
    12541 gcatcgcaat ctgcaattat cggataatga gcgacttgaa tttttaggag atgccgtttt
    12601 agaactgatg gtttctcagt atttattccg tttatatcct catttgccag aaggaaaatt
    12661 gacaaaaaca cgagctgcga tcgttcgcga agacagcttg tcgaaatttg ccaaagaatg
    12721 tcactttgat caatatgttt tgttgggcaa gggagaagag aattcaggag gacgtacgcg
    12781 accagcattg ctttgcgacc tattcgaagc ttttttaggc gcgttatatc ttgaccaggg
    12841 attcgacacg acccatgcat tcatcgaaaa agtgattttt cctaaagtca aagcaggtgc
    12901 tttttcacat gagatggatc ataaaacaaa actacaagaa gtcttgcaaa aatcaggtga
    12961 tgtatcaatc gaataccgat tgatcaatga agaaggtcca gctcatgaac gagtattttg
    13021 gatcgaagtt tatgtagatg atcaattgat tggcactgga caagggaaat cgaaaaaatt
    13081 agcagaacaa gctgcggcgg aaaatgcatt ggcagcactg taaaagtaag tgagggaaag
    13141 ctttgtattt gaaacgaatt gaaatagccg gttttaaatc atttgcagac aagacagtca
    13201 ttgattttga aaatagcgtc acagcagtgg ttggaccaaa tggcagcgga aaaagcaata
    13261 ttacagaggc tatccgctgg gtattaggag aacaatctgc taaaagtctg cgaggcggaa
    13321 aaatgccgga tatcatcttt gccggttccg atacccgtaa gcagctgaat attgcagaag
    13381 tcacagtgat tttagacaat agtgatcatt atctgccatt ggagtacaat gagatcagtg
    13441 taacccgccg ttatcgacgg actggggaaa gcgagttttt catcaataaa caaagctgca
    13501 gattaaaaga tatccaagaa ttgttcttag attctggatt aggaaaagaa tcgttctcaa
    13561 tcatttctca aggaaaagta gaagcgattt tcagtagtaa accggaagac cgtcgtggga
    13621 tctttgaaga agcagctggt gtcttgaaat acaagcagcg gaaaaagaaa gcagaacaga
    13681 agctttttga aacagaagac aacctcagcc gcgtccaaga catcatccac gaattggaag
    13741 aacagttaac tcctttggcc gcccagagtg aggcagcaaa ggagttttta cggctaaaag
    13801 aaacactgac tcaaaccgat gtctctttga tggttgctga aatcaagaca gcaaaaaaag
    13861 attgggacaa caaacaagca cagcttgcga aattcaatct agaattaggc aaactatctg
    13921 agtcgatcca agaacaagaa tccattttgg cgaagcagcg taaagaaaat gcgcaagccg
    13981 atcgtctgat cgaaaaaaat cagcaagtat tattagatct ttcggaaaaa ctgaagcaga
    14041 cagaaggaca aaaagatgtt ttgcaggagc ggacaaagca tacacaaaaa agctcgcaag
    14101 aatatcaaac ttcattagca gaagcacaaa aaaaggttaa acattttgaa aagcttcaag
    14161 aaagcttgat gaaagcagca gcagaaaaag aaacagagat ccaaaaagct gaagcaaatc
    14221 tcataaaaac acagcaagaa ttagaaaaat accaaaaatc aacgaaagaa ttattggcag
    14281 aattaagaga tcaatatgtt gatttgatgc aagaacaagc agctgtagga aacgaactga
    14341 agtatctaga acgtcaatat atacaagaaa cagcaaaaag caagcagacg ttagccaagc
    14401 aatcggaagt agaagcatca gtagaccgat tgatcttaca aaaagaagaa ttgacacaaa
    14461 agcaggcgca gctaaaatca tctttaactg aaacaaaaga gaagttagaa atgatccaac
    14521 aaaacgggaa aaagttccaa gaagcattag caaaagaaca gcctaaaatg tatcaattaa
    14581 tgaatcaagt ccagcagcta cgtgctcgta agaaaagcct tcaagaaatc caagaaaact
    14641 attttggttt ttaccaaggg gttcgattgg tcttgcagca taaacagcag ctttcgggta
    14701 ttgtcggagc agtggctgaa ctgatcgatg ttcctgcaga tttcacgtta gctatcgaag
    14761 cagctttagg tggggcagcc cagcatgtca tcgttgaaaa tgaaaaagat gctcggcaag
    14821 ccatcacgta tttgaaacag caaagaggag gaagagcaac attccttcca ctgacgacaa
    14881 tcaaaccaag acaattaccg gctcatatat tgacacaagc agcagctgta gaagggttta
    14941 tagggattgc cagtgaacaa gtcagttatc ccgatcaaat ccaaactgtg gttcaaaacc
    15001 tgctaggaac gatcctttta gccaaagact taactagtgc caatgcaatc gcgcaaacga
    15061 tccgctatca atatcgagtg gtttccttag aaggtgatgt gatgaatgcc ggaggatcca
    15121 tgacaggtgg agcgaataaa cgaggaaacc aaggcagttt gtttgtacaa aatcaagaat
    15181 tgaaacagtt gactagtgaa tttgaagaag cagataaaca actccaagca caagaaaaaa
    15241 aagttcagga gctgcaacaa gaaacagctc gtttagccga agaacaagaa gttttgcgta
    15301 cacgaggcga acaattacgt tttgaagaac aagaagcgac aaatcagcta caaaacatca
    15361 taaatgaact tgaacgtttt gaaaaagaaa agcaaatctc aacttttgag acacgtgaac
    15421 tgcagcagtt tatcgaagat tacgaaaagc aaacgaacga attgaaagac aaacaaacag
    15481 atcttgaatc gcaacgacaa aaaatcgacg aagaaatcaa atcgttaagt caagaaagcg
    15541 accagatgga agccagaaga gcacaagtac aaagtcaaaa agcacaagaa caagcagatc
    15601 ttgctgtctt gaaagagcag tttaatcatc tgcagatcca gctccgcggt gcccgagtcc
    15661 aaaaagcaga ggcaaccgaa cgtcaagaag cgatagaaaa gcagttggcg acattgacag
    15721 cagacttttc tgatcatgaa gtcacagaag aaagtttgga aaaacaaatt aacgaattat
    15781 ctgctcagcg agaaacatta aaagccgagt tggcaaaagc caaagagcag cgagatagaa
    15841 ggcaaaagga gatcgataag cttgaagcag tcttggcaga gcgtaatcgt gagcaaaaag
    15901 cacgactgtc ggaacaatcc aaattagaag tccaaaaaga ccgagctgaa atgattttag
    15961 ataatcattt gacctatctg cagtcagaat atcagctgac atttgagaaa gcttcccaag
    16021 actatcaaga aacaaccgat atcgaagaca gtagaacaaa ggtttcatcc ttaaaagaac
    16081 agattgaaaa actgggacca gtaaacttaa attcaatcga acaatacgaa caagtcagtg
    16141 aaagacatac attcttagca acacagcgag atgatctgtt agcagcgaaa aaccaattgt
    16201 ttgaaacgat ggatgagatg gatgatgaag tgcggacaag attcaaagaa gtatttgaag
    16261 ctatccgtca agaattcaaa attgtctttc caaatatgtt tggcggcggt aaagctgaat
    16321 tagtactgac ggaaccaact gatttgctga aaacaggtat tgagattgaa gtacaacctc
    16381 ctggcaaaaa actgcaaagt ctaagtttgc tttctggagg agaacgagca cttacagcca
    16441 tcgcgttgct cttttccatt atccgtgtct gtcctgttcc gttttgtatc ttagatgagg
    16501 tagaagcagc gttagatgaa gccaacgtga aacgttttgg tcgttacttg agcgatttcc
    16561 aagatgacac acaatttatc gtagtcacac accgcaaagg aacgatggtc gcagcagatg
    16621 tactgtacgg agtgacgatg caggaatccg gtgtatcaaa aatcgtttct gtacggatgg
    16681 aagatatcaa tgaagaggcg aaaatcaacg aaacgaaagt gtaggaacga aaatgatcaa
    16741 attagtagca atcgatttgg acggtacatt attaaatgaa caaaagctga tttcagatga
    16801 gaataaacaa gcattagcac aagcaaaaca gcaaggggtc aagatcgttc tatgtacagg
    16861 acgcccctta gctgcgatgg cgcattatct gcaagaatta ggactggtag atgaaggtga
    16921 ctacagcatc actttcaacg gcggtttggt acaaaaaaat gatactggtg aaatcatgga
    16981 aaagaaagtg atggaagtat cagatatcca acgcttatac aaactggctc agcaattgga
    17041 tctgccacta gatgttttgt ctgacaatgt ggttttacag ctgcctagtg ccccaaggaa
    17101 gcaatccttg tacaatgtgt tgaataagct gctgcaattc caaccagcgg atataagcga
    17161 tattacagat gaatttgtgc ttaataaggc agtaatcgct tatgaccaag aagaattaga
    17221 tcctaaaatc aaagaaatac cagcagaatt ccatgaaatg tatgagatca tcaaaacaag
    17281 aagtatgctt ttggaattta tgccaaaagg tgttacaaaa gcttatggta tttctttatt
    17341 ggcaaaagat cttggtttga aacaagaaga aatcatggcg atcggtgatg aggaaaatga
    17401 tttaccgatg atccaatatg ctggactagg cgtagcgatg gagaatgctg tgcctttcgt
    17461 caaagaagca gcagatttcg tgacagccag caatgaagaa aatggcgtag ccaaagtgat
    17521 ccaaaaattt gtattagagt agggggagtc aaatgggatt ttttgataaa atcaagcgtg
    17581 cttttactgg cgaagagaaa acagaagaag ttgaagtaca ggagaagtac gacaagggtt
    17641 tagaaaagac gcgtaaaaca tttggtgaac ggatgaatga gttgtttgcc aattttcgaa
    17701 cagtcgatga agactttttt gaagaattag aagaaacact tatcggtgca gatgtaggtt
    17761 ttgaaacagc gatacgaatc accgaagcat tacgtcaaga agtgaaactc agaaatgcga
    17821 aaaaatcggc agaagtccaa aatgcgatca tcgagaaact tgtggatctc tatgaagcgg
    17881 aaggaatcaa tgaagtaaat gaactaaata tccaagaaga cggactaaca gttattttgt
    17941 ttgtcggtgt taatggtgta gggaaaacaa caagtattgg taaacttgcc catcagttca
    18001 aaaacgaagg taaaaaagta ttgatggcag cagcagatac cttccgcgct ggagcaatcg
    18061 accagttagt tgtctggggc gaacgcgctg gtgttgaagt tgttcgtggc aatgcaggag
    18121 gcgatccagc agctgtcgta ttcgatgctt tggaaagagc aaagacagag caggcagatg
    18181 ttttactagt tgatactgca ggccgactgc aaaataaagt gaacttgatg aacgaattag
    18241 aaaaaataaa acgagtaatc cagcgggaat taccagaagc accccaagaa acacttcttg
    18301 tattagatgc aaccactggt caaaacgcga tggttcaagc aaaacaattc aaagaaacaa
    18361 cagatgtgac cggtcttgtt ttgacaaaat tagatggtac agcaaagggc ggtatcgtac
    18421 ttgctatccg taatgaattg catttaccag tgaaattggt cggtcttggt gaaggaatcg
    18481 atgacttgga gccgtttgat ccaaatgatt ttgtcgttgg attgttcaaa ggattactaa
    18541 aagaagaata acccatgtct aaaaagcagg agctgtgaca aaagttgcag ctccttgttt
    18601 gaatgattgt ttttaacata gctgtgtttt tgatgccttc atttttatac ttatttgtaa
    18661 gcggttctca aacaatttcg ttctttttct tagacttttt gattataatt agattcatat
    18721 gaattggagg tcacttaatg atgaatttta agcaattatt attgcatgtc aatgcgcgcc
    18781 cttttatcga ccaagctcga tttggtatag aacgggaagg acagcgggtt gatcttgcag
    18841 gaaatctagc aaaaaccgat catccagcaa tctttggcga tcgatcctat cacccctata
    18901 tccaaacaga ttttagcgaa acacaaacag agatgatcac ccctgttacc gattctattc
    18961 ccgaattatt tcagtatctc gctgctgttt atgatgtgac tgctcgttct ataccgaaag
    19021 aagagatgat ctggccatta agtatgccac ctgccttacc ggaaaaagac gaagagatca
    19081 ttattgcaaa attaaaaaat ttcgaagatg tcttgtatcg acgttattta gcaaaaaaat
    19141 acgggaagcg aaaacagatg gtaagcggta ttcatttcaa ttttgaattt ggcgatgagt
    19201 tgctaagaac attgttcagc catcaggaag aatttcaaga tttttccgaa ttcaaaacag
    19261 aactttattt gaaaacagcg agaaacttta tgcgctatcg ctggatgatc acttatttat
    19321 tcggtgcttc accaatgagt gagaagaact actttttaga tgaatcacat ccgcaagaac
    19381 ctgttcgcag tattcgcaac agtgcgctgg gctatacgaa tcatccaaat gtgaaagttt
    19441 cctatgcttc tatgaaacag tatttagcag atatcgagcg aatgatcgaa gaagggaaac
    19501 tttcggagga gaaagaattt tatacaccgc ttcgtttccg aggcggaaag aaagtcgcag
    19561 atttagcaac aacaggtgtt cgttatattg aattgcggaa tatcgatttg aatccttatg
    19621 caagattggg tatcaatcca gagcaagttc ggttcttaca attattcctg atgtacatgt
    19681 tatggacaga agaaaaagaa gactgtgacc aatgggtagc agaaggtacg actcgaaata
    19741 acaaagtagc actagaacaa ccatcagatc aaacagaatt tcatcaagaa ggtagagaaa
    19801 ttcttgaagg aatgaagcaa atgctggttg aattggattg gttggattct ctttatttag
    19861 tagaggaagc attgactcaa atggatcatc ctgaacaaac gttagcagcg aaactctatc
    19921 aagaagcaca gctatcgagt cagcaagaag ttgctgtggc attgggacat caatattata
    19981 aagaaagcca tgaacgtccc tatcagttgg ccggttttcg cgaaatggaa ctttctactc
    20041 agatatttat gttcgatgcc atccaaaaag gtgtccaagt caaagtatta gatgagtcgg
    20101 atcaattttt gcgtctgcaa ttccaagacc atgtagaata tgtgaaaaat gcaaacatga
    20161 caagtaagga cagctatatc gtcccactta tcatggaaaa caaaacagta acgaaaaaag
    20221 tcttaaaaga agctgggttc cgggtaccag gaggcgcaga attttcatcc atggaagaag
    20281 cggtaaaagc ttatccgaga tttgccgagc aggcatttgt gatcaaacct aaatcaacca
    20341 attacgggtt aggtatcacg attttcaagg aaggagctag tctggaagat tatcaagcag
    20401 gtttagccat tgcttttcgt gaagacagtt cggttttagt agaagaattt atgccgggaa
    20461 cggaatatcg tttctttgtg atcgacggag aagtccaagc catcatgttg cgagtccctg
    20521 ctaatgttat tggtgacagt atccgaacag tgaaagaact tgttgaagaa aaaaatagtg
    20581 accctttgcg tggaacgaat catcgtgcac ctttagaatt gatccaatta ggtgaattag
    20641 aacaattgat gttgaaagaa caagggttga cgatcgaatc agttccccaa gccaatcaaa
    20701 ttgtttatct aagggagaac tcaaatatca gtacaggtgg tgattcgatc gatatgactg
    20761 atgaattttc tgaagcttac aaaaaaatcg ccgtttctgc ggtagaagca ctaggagcta
    20821 agattagtgg tatcgatttg attataccag ataaagaaat cgatcctaca actgataaaa
    20881 aagcatatgg gatcatcgaa gcaaatttca atccagccat gcatatgcat gtttatcctt
    20941 ttgcaggaaa aggcagaaga ttgacgatga atgtattgaa attgttatat cctgaagtat
    21001 tttaaaagaa aaagcttttg acagattgtc ctatttgatg tcaatctgat caaaagcttt
    21061 ttttgcatgt aaaaatttat gtgttttttc gttttaaaat aaacgatccc agaagctttt
    21121 tttctttttt ggtttttctt tttcagctgg cgaagagttt tcttctgggt attttttttc
    21181 gatatcaatc acaggttcat ttactgcttc ttttgctgtt aagagcaatc cgaattcctc
    21241 aggatttgca gtgacgtaat cgttgactac agtgaaacgg ctattgtttt tcgttgctag
    21301 ctggatatat tggttttgga cagaaagggg tagagcccca ttcaagagta tggaagcatc
    21361 tggatgtttt ttgagttctt ttaaaaagtt ttctttgttt tttggttgga tcatttcagc
    21421 aacagtcata ctaagatagc agcgttccct gaatgtccct aaatatttat gctgttcttc
    21481 agggttcact aaaggtgtac cataaagtcc cttatccaaa tggcttttta catcatcttg
    21541 tgccataaaa aataccctcc ttcttctctt tgtctttctt acgattatag catattccca
    21601 ataataccta aaacatatga aaaagcggtt gcttttgttc aacgattcac ttaaaataag
    21661 aatgaaaatc attctcaatt agaaaggtgg attggatgcg ctacggacga ctagtagcat
    21721 tattagttat tttaagtagt atttcattgt tcatcggagt atcgaatgta caattgtcag
    21781 aactgctcca gttagatggg caaagcttac aaatcttgct agtgactcgt ttgccacgaa
    21841 cgatttgttt gatccttgtg ggagcgacca gtagtatttg tgggttgatc atgcaacatt
    21901 tgacccaaaa taaatttgtt tcaccaacga ctgcgggcac gatggatagt gcgcgtttag
    21961 gtattttagt ggctatgatt ttcctacctg gtgcatcctt gattgtccga tccttgacag
    22021 cattttgctt tgcttttgca ggaacattgc tttttttatc ccttacgcga ttgttcctcc
    22081 agaaaaatca attgatgctt ccgttgattg gagtcatgtt agggaatatc attggttcag
    22141 ttgctacttt ttttgcttat caattccagt tggtacaaaa tatgacttca tggcttcaag
    22201 ggaattttgc gactgtgata cgaggaaatt atgagttatt gtatgctgtt gttccattgt
    22261 tgctcttggt ttggctattt gcttaccgat ttacgatcat tggtctgggc gaatcgtttg
    22321 cagtaaatct gggaatagat taccagaaga tgcagttttt aggcattggc ttagtatcat
    22381 tggctagtgc agtcatgttg atcatggtag gaagcattcc ttttatcgga gtgatcattc
    22441 cgaatcttgt ctctagaata tatggagatc aagtgcacaa aacaattggc gtaactgctt
    22501 tagcaggtag tttgttctta gtattttgcg atcttgtcgc tcgcgtgttg atttttcctt
    22561 atgaaatacc agtcagtgtg atcgttggaa tcatcggtgg ggctatcttc ctttatcttc
    22621 tgataagggg acgacgatat gcttaaaaaa aagccatcta tttttattgg tatgcttgtt
    22681 cttgttttat ttgttacagg aatgtacttg acgatccata catatggaaa ctggcatttt
    22741 gcatgtgcat tgaggagtaa gaaaattttt gcatttatcc ttgtctcgct agctgtcagc
    22801 agtgccacaa tcagctttca gacaattacg cataaccagt ttttgactcc ttcagtattg
    22861 ggacttgagt cgttatatgt ccttgtccaa acggtccttt tcttctttat cggaggagtg
    22921 acgatgcttc agcagacagg tacagttttt ttcttattga acgttgggct gatggtcggg
    22981 ctgagtctat tgttattttt ctttcttttg aaaaaaatga gagcgaatct ttttttatta
    23041 ctgatgtcag ggatgatttt aggtacgctt tttggtagtg tcagtacctt tttacaagtc
    23101 atcatggatc cgaatgaata tgatttgctt caaggcagat tatttgcaag ctttggcaat
    23161 atccagagtc agtatctttt gcctgcttct ttgatcatta tcggctgctg gtacctgtta
    23221 tttcgatatc gacatgtgct agacgttttc catctcggaa atgaacaagc agtaaacctc
    23281 gggatagaca cagatcgttt tgaatttttg attttatgtt gtgtcagtct tttgacaggg
    23341 acatcaacgg ctcttgtggg tccagttact tttttagggt ttattgtcgc aaatatcagt
    23401 tatcgtgtct tttctactta tcgtcatggt cagctattta tcggaagctt tctggtagct
    23461 atgctgtttc tgacaggagg acagctcgca gtagagcaga ttttcggctg gaatacaaca
    23521 gtgagtgtcg tcgttgaatt tgtcggagga atttattttg tcacaaaatt gattcgcgaa
    23581 aggaagagta tcctatgatt gatttacaaa aggtcaataa actgtaccat ggaaaatcag
    23641 tggttaaaga tgtacagtta acgattcctg aaaagaagtt gactgctttt atcggtccaa
    23701 atggtgctgg aaagtcaacg gtgttgtcga tgatcagtcg tttgatacca aaagatacag
    23761 gtgaaatcta tttagaccat aacgaagtaa aggcttggaa atccaatgaa ttagccaaaa
    23821 aattatcgat cctacgacaa tcgaatgaaa taaatgtcca aatcaccgtg aaagaattag
    23881 tagaatttgg acgatttcct tatacgaaag gaaaattgac gacaaaagac gaggaaatcg
    23941 ttcaggaatc actggaacac cttgggttag aagaaatagc ggatcaatcg attgacactc
    24001 tttcaggcgg tcaactccaa cgtgcgtata ttgcaatggt gctagcgcaa gacacggatt
    24061 atattttact ggatgaacct ttgaacaatc tagatatgaa ttttgcggtt caaatcatgc
    24121 agattttaaa aaatttagta caagaaatcg ggaaaacaat tgttattgtt cttcatgata
    24181 tcaactttgc tgcaagttat gcagacgaaa ttgttgcaat gaaagatgga cagttattta
    24241 cgcaaggaac gacccaagaa atgataaaaa aagatgtatt ggatgaatta tacgaaatgg
    24301 acatacggat ttgtgagatt gaaggccgca gattctgtct ttatttctaa aactaacatt
    24361 aggagagaag agatgaaaaa attagtagta ggtatcttga ttctagcatc atttggttta
    24421 gcagcatgtg gaaatagcaa caacaccagt caggcagaca caaaaaaaag cagcacacaa
    24481 actgaaacta cattgacgat aacagatagt aatggagacc aaatcgaggt gccaaataat
    24541 ccagaaaaag tcgtcgtatt cgacaatggt tctttagata cgatggatgc tcttggtgtt
    24601 ggagataagg tagttggagc agctacaagc agccttcctg agtatctttc atcctataaa
    24661 aaagtagaat cagcaggtgg aataaaagaa ccagacttag aaaaaattaa tcagcttcag
    24721 ccagatctaa tcatcatttc tggccgacaa agagattttc aaaaagatct aagtcaaatt
    24781 gctccgacca ttttcctttc tttagatgcg aaaaatccat gggaatcttt ccagcaaaat
    24841 gtcactgctt taggggagat ctttggtaag caagaagaag ctaaaactca attagaggaa
    24901 ttatctagtg caatcgatca gacgaaaaag aaagcagaag ctactgacaa aaaagcacta
    24961 gtcacacttg tgaatgaagg gcaattatca gcctacggat ctggttctag attcggtttc
    25021 atccatgatt tatttggctt tgaacaagca gatgatcaaa tcgaagcatc cactcacggt
    25081 caaagtgttt cttatgaata tgtgctggaa aaaaatccgg atatcttatt tgtagtagac
    25141 agaacaaaag ctattggtgg agacgacagc aaagatgata tttctgccaa tgaactggta
    25201 gcacaaacga atgctggtaa aaatcagcag atcatctccc ttgaaccaga tgtctggtat
    25261 ttaagcgggg gcggtttaga atcaatgaaa ctgatgatcg aagatgtgaa tcaagcattt
    25321 aaatagcata aataacagag gattaaactc tcatactatg taacaataat gtttcttaca
    25381 ttcttaaata gcaagagcct atcctcaaag aagttatcaa aaaccatccg taaaatcgta
    25441 ttgatgattt tacggatggt ttttatttat ttgagaaatc ttttttcaac gtgaattcat
    25501 tatctacatc atacgggttg attctagaat ggggagtggc aaaaaatagt gtgatccatt
    25561 ttttcagcat caagatcgcc tcctttgatt tgaatcaaag gtacaaagcg aaacttagat
    25621 aaaacttaaa tttagatatt tttattttgt accgatctct tctttaaacg atgttccatc
    25681 tgctgcttct cggcaataag tccactagac tagaaaatat gagaagctat tttctgtcca
    25741 gcgttcttat tactcaaaac aaatcgcagt tgtcacaatc tcttctaaac gatgttccat
    25801 ctgctgcttc tcggcaataa gcccactaga ctagaaaata tgagaagcta ttttctgtcc
    25861 agcgttctta ttactcaaag caaatcgcag ttgtcacaat ctcttctaaa caatgttcaa
    25921 tcagctgacc ttcggtatta gctcaaagca ctgatttcac aacctctatt taggcatgtg
    25981 tctcagcaag cggttgatag ttgatgatct gcatttttcg ataaaaatcg gcgggaagct
    26041 tactccaccg ttttagtaat tgatagaaat aactctcttc tgctttgatt ttatactcgc
    26101 ttaatatcaa tccaaaacta ttcgtttttt ttgaagctaa ttttttataa atatccaatg
    26161 ctttggtttt atcttcattg acaaagagtg tttttacttc aatataagaa ccctcgatat
    26221 tttgtgtttc ttcgataaaa tagatgtttt ttatatattc cttcatagtg attcctccaa
    26281 agaagtcttt tatttgataa gtttactcta ccgaagagtt gttaataatc cgtgaacaaa
    26341 aagtaattct ttttccaata gttgttaaag gttttttatt ttttatagta ttttttgtta
    26401 tttaagaaag gaataaggtt aaacaaataa caggttgctt tttgggtctt tttccgttca
    26461 agaaactgaa cgaagaaaag ggaaagttgt ctcttttgtg ataagagaaa tcataataaa
    26521 cgaatgactt actttccaat aaattgagaa cagtcagaac cagacaaatt agttgcatct
    26581 gatgaataaa gtgattattc tatgacatga ggtgatacag atgaaattag aagtgacaaa
    26641 agaagcacaa gaagtattga agaataaatt agaagcagac gatcaacttt tattagatat
    26701 cgaaaacggt gacggtccat ttgcagaaag ccaagtcagt tgccaattgg atacggcatt
    26761 tcgattgatc attgtcaaaa aagatacaca aacagatcta agtctttatt ctgtagtggc
    26821 tgatacacca gttggaccaa tcaaaatcaa agacagtgca atactttaca tggatgatcc
    26881 atccacactt gctttagaac caacttataa tagtttacaa ttaaaaggac caagcggctt
    26941 gagaaaaggc aacttgcaag ttgttcgaaa agactagagg gataaaatgg gaaaattggc
    27001 gatcatcagc gacctacatg tggacatcaa taaattcggc gaatcagagc tgatgcagct
    27061 ttggcaagtt ttgcaaaagc acaagatcac tcggcttcat ctagccggag atacggctaa
    27121 taaagtagac cgttgcctag ctgttgtcga atttttcgtc aataaaggat tatctacgac
    27181 atttcatttc ggcaatcacg agttggcaga tgtgcccaat gaacagatga tggaccattt
    27241 tccagaccca cattttttaa atgaacggta tattgcttta aatgagcaga ccgttctttt
    27301 agggatgaat ggctggtacg actatcagtt ttccgaattg aaagattacg aggcaatcgt
    27361 acgaatgaag cgtttgtatt ggtatgatcg gttcatccag cgtgggaaaa cagatctcga
    27421 ggtcaatgca gaaatgcttg cagctgcaaa aaatttgcta gaccagctgg aagcaaaaaa
    27481 acttgaggtg attttatcca ctcatttcgt tcctaaacgg gcatttatca tgtatcaatc
    27541 tgctccttat gagcgttgga acaaattaaa tgcattttta ggatcagaat cattcggaga
    27601 attacttgac cgttattcaa atatcaaaca agtagttttt ggccatacgc atcgtcgctt
    27661 tgaagataaa tccatcggtc acacgattta cagctgcaga ccttttggtt attattatga
    27721 atggcagctg acccgagatt ttgtcttgaa agaacagttg ctagacagct atgatcctat
    27781 gaaattacgt gtcctcttgc gtgcccatca cccagctttt caggcctatc aaacacaaca
    27841 tttgcaagag gaatttgaac aagcgatgac aatcgttccg tattgagaca gcattagtaa
    27901 tgtgtaaaag aaaatacctt gtaaaacata aggataagta agagcagtag atccatttat
    27961 cgtggatatg ctgctttttt tgcggaaaat aatcagcgaa tgtttatttg atcggatgat
    28021 ttgtaactcg cagagtacta gatgcaagcg tgtattcttt ttttgaacga taatcacaaa
    28081 aaaaaatata atatacattt tttatttaat tataattaat attgattgaa gtctaggcag
    28141 tcaagtcaca ttttgataga taggaggggg acttacgaat tattttaaag gctatgacag
    28201 ctgtatttct agattgtgtt tgcatcaagt tgcaataaaa actagaaatc aaatcgggct
    28261 gataatcatt tataactaat cgatacatag gaccaaatat aggtctatgt tcttttattt
    28321 cataagtatc gtaaaacaga attttgctat ggattaatcc aatcgactga tatgtttagt
    28381 aaataaagaa agaggaatgt caatgatgaa aaaagaaatc gtattaacag cagcaatgat
    28441 gttattcagc atggtagcaa gtacgacttt tgtttctgca actgaagtat acccaaagga
    28501 atataacaca gaaggaacga ttacatttga agcaggagat gagggtgtaa ctcctcctgt
    28561 tgatccagag aatcctgatc ccaataaacc tgtcgatcca tcagatcctc caagccctgg
    28621 aacaggaggg gcattatcga ttgattatgg atcaaaattc aaatttggga ctcaaaaaat
    28681 ttctactgcg gataaaacgt attatgcagc tgctgatgtg atgaacgatg ggtctagaaa
    28741 accgacatat gtccaagtga cagataggag aagtacctta tctgggtgga aattaagtgt
    28801 ctctcaacca gaacagttta aaactgccag tggggatgaa ctagttggag cacagctgaa
    28861 atttacgaaa gggcaggctg tttctttggt tgatccaaca tatacgccgc aaacggtgaa
    28921 ttctgaatta acgttgacac cgggaggaaa caatacgtta gcaattaatg ctaaatcagg
    28981 aacaggtgtg gggacttggg tctatcgatt tggtgcaaat gaaaatgaaa atcaagatgc
    29041 ggtacagctt tcggtacccg gtaaatctgt caagttagcg caacaatatt ccactaaatt
    29101 agtttggaca ttagaagata cacctaacaa ctagtttact gaaaagaact gttaaaaata
    29161 aatacgtagt catattgtct tgcgaggtaa tcgagcaaaa attgtcaaag gctaggctaa
    29221 atttgtttgg atacgaatag ttcatctagg aatttaacga tcaggaggaa aagatatatt
    29281 gaaaaagagg aggatcgtgc tcattttaag cagtctctta gtgactaata tctttccgat
    29341 catagggtac tctttggaat tgaatcagtt ggagcatgga aatagaagag acgaagaaag
    29401 caaactcact tcgacattcg acagtttaat agaatccaac cagacacaag aaagcagtga
    29461 ggatttaagt atttcgagta gtggagagac cactgacaac gtagaagctg agggttcgga
    29521 caaacaagga ctagaagatg caccaatttc tgcggttgag ctgcctgacg atcccaatat
    29581 tatttctatc gataaaattt ttcaaacacc tatcggtact agcacgtcca tattggaaaa
    29641 tgggaagtta ctgcagttga acccagcaga aaggtctcaa agaggagcta tttggtcaaa
    29701 taagaagatt agtttactct cggattttac atttaaatct tatttatact taggaaatca
    29761 acgagataga gcgggagatg gcatgacctt tacattgact ggcgatccta gaatggctag
    29821 taatcccagt caagttattg gatcgccagg tatgggaatt ggctcatatt ctactcgttc
    29881 tggccaacct tacattgcga atgcgctctc gattgagttt gatacgtata aaaatagtgg
    29941 ttcttctgat cgaatggatc gagagataac tgctgataat agagggcatg gacatgtcgc
    30001 ttttgtcacg cctaaaccaa ataataataa ttattctgga gagcatactg gcgtgacggt
    30061 agctcctaca tttctttcta atggcacatg gcgcttgtta ataattaaat gggacgcgga
    30121 gcaaagaagt cttacttatg atttggaagg tgtcggtcgc tcttctcgga ttatacctga
    30181 tctcattagg cagtttggtt ctacagaagt aaattggggg tttacttctt caacaggtac
    30241 tttttttcaa gaaaatgctg tcgctgtcac gcgacttcca tcgaatgtca catcaacagc
    30301 tgatgtaaaa gtcaacgata gtgattatgg ggccatcgct gaagctggag gaaacgataa
    30361 gataactatc agaaatacat tgaaggtcga gggggatttt cttgaatata agaaaatgca
    30421 gactagtatc gacctcccac aagaattaac tattcccgag catatcttga tcaatggaaa
    30481 tcaaattgat gccaaagata tcttgataac cggaaatcga gtcacgctaa atctgacaga
    30541 ttattttatt gctggagata cgttaataat cgaattggag acaactttgc aggaagtaat
    30601 tcctgaaaaa gtactcacta tgcattttga ataccttgaa aacgggaatt tgattgagca
    30661 atcgaatgaa ataaacctaa agatcgcaaa gctgaaggag atagatatcc atgtttatta
    30721 taaagataaa gacagtcaga ttgatattgc tgaaatgaaa acaatcactg ggaaaatagg
    30781 agagaagtat aaagaaactc ctattgatat tgaagggtat gtttttgact cggattcagc
    30841 gaatacagaa ggcatcttct ccgaaaatac agaggatatc tatttttatt acagaaaagg
    30901 caaactttat ctctcaactg ctcctcaata tgtcaatttt ggaaaacata aaatatccag
    30961 tagaccatta agtgaattcg gacagttttc aggtgggttg aaaattatag atgaacgggc
    31021 ttttggaagt tggaaattac aattgaaaca agagaaagtt cttacaaatg gagattttga
    31081 gcttccagaa gctctttcct ttgttacctc tgaaaataca acggttatag ggacatccgc
    31141 tgttacgatt ttcgaaagtg atcaaaaggg tgaaagcgat ttgtcctctc ttttagattc
    31201 tacagctcat cgtggaatca gaataaatat tcctgtagaa aaccaaagaa tcggaacctt
    31261 tgaggggaaa ctatcttgga tacttgcaga tgtcccagga aattaacagg aagagaagaa
    31321 tataacaaaa ttattgagtt tcaagaaggg cacaggtacc ataggctctt gtgtcccaca
    31381 gagacaagat tttgttatag tcttctctta catatgatta aaggagcgat tttcttgaga
    31441 ccaaaacaac aattatttat aacactccta gttattttag gggcactttt taacaatata
    31501 tcagtgtcag ctagtgcatt taatttttca gtgacgccga taacttcaga gaatcaaatc
    31561 gacaagagaa aaacttactt cgatcttcaa cttgatccgg atcaggaagt agaagtaaaa
    31621 gcggaattga gaaatgatac agaaaaagaa gtgaaaatcg atatttctgt gaatagcgca
    31681 accaccaatt caaatgtgat ggttgaatac ggaaaaaacg agattgaaaa agacatgagc
    31741 ctgatctttg atctggtaga ttatgtgagc tatccacaga tagtgacgct aaaacctaaa
    31801 agtgtccaaa ccgttgcttt tcatgtcagg atgccgaatg agcgatttga tggtgtattg
    31861 gctggtggga tcacattcca agaaatccag acggaaaagg accaaacaga aactaaggat
    31921 caaagcttat cgattgagaa tgaatacacc tatattattg ctttgttgat gcaacagaca
    31981 ctgaacgaag ttgctccgaa ccttactctt catgaagtta aaccagatca aatcaatgca
    32041 agaaatgtca tcttagcaaa cgttcaaaat gatcaaaaaa cctatatcaa tcaagtagtt
    32101 attgaaacaa aaattacaaa aaaaggacat tctgaagttt tatatcaaga ggaaaaagaa
    32161 ggattgcaga ttgcgccgaa tacaaatttt tcttttccaa ctgctttaaa tggtcaaccg
    32221 ctaaccccag gtgaatatca ccttacaatg actgttttag gaaatgaaaa tgaaaatgga
    32281 aaattttcga gaaaaaaagg aaatactacg atcaactata ccaatcaatg ggtatttgaa
    32341 aaagatttta caatagacgg aaaagtagcc aaggaattga acacgacgga tgttacgatt
    32401 aaaaaagaca ataattggat ttatatctta gtagcttcac ttttcttatt gtttatttta
    32461 ttatgcatac ttttgtttgt tttgagaaaa aaagaagaga aagaaaagta aggttaagat
    32521 aacaaatagt aaatttttat tattgtagga tggttgggct ctttttataa caatataaaa
    32581 tataccattt tattaataaa aatgcatact agtaaatgat ataattctaa taacaggttt
    32641 gatcgcgaga aaggccaaat aaaacgctct ccaaaatgtt aaaaaaaaga caggacgatg
    32701 tatattatac aaacaagaat cgctgacaac agtgactcgg atccaggaaa tcagttttat
    32761 ccccagctag ttggtgaatg catggaaagt aatatacgta gaaagagctg atgactaatg
    32821 aattatgagt tttttttaag caaagaagat cacagaagtt attcattact taaatattta
    32881 gaagcaagct caaatttatc agagtcaata tcgaatgttc aagaagagtt gtcgctatcg
    32941 acatttctct tgaaaaaaac gatcgataag ctgaaacatg atttacaaaa gttcgatcta
    33001 gagaaaaatt tgcgagtaac cgtcagtgaa ttggatatat gtctggaaat taatggaaaa
    33061 tgttctagca aagctctgtt atctcgttat ataacggatt ctttatctat gaaaatggta
    33121 ttggctttct ttcaggaaaa atatatctca gtagaaaatt ttgctaaaca gcatcacgtg
    33181 agttattctg tggcttataa agtattacaa agactaaaaa gaaatctaaa aaaatatcaa
    33241 attttttttg aaaagagaaa gtt
//
LOCUS       DADQDV010000029        31014 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.029, whole genome shotgun sequence.
ACCESSION   DADQDV010000029 DADQDV010000000
VERSION     DADQDV010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 31014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31014
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.029"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(405..2480)
                     /locus_tag="J8S10_001414"
     CDS             complement(405..2480)
                     /locus_tag="J8S10_001414"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HAZ9630002.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDVKTGRASRGHRFLGEDVTFAHAKEYEEKLNEQFVIASPQKR
                     QEMIVTQANELAEKNHWVIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGELPQSTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISD
                     VISKDTDRFGIGLSEGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAELEKQSEVDPELFENEAEKELHKAVEA
                     MKKSFADQTINENYDQLVSLRPLIENYFDQTMVMAEEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
     gene            complement(2482..3399)
                     /gene="glyQ"
                     /locus_tag="J8S10_001415"
     CDS             complement(2482..3399)
                     /gene="glyQ"
                     /locus_tag="J8S10_001415"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HAZ9630003.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENMKEAE"
     gene            complement(3783..4595)
                     /gene="recO"
                     /locus_tag="J8S10_001416"
     CDS             complement(3783..4595)
                     /gene="recO"
                     /locus_tag="J8S10_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HAZ9630004.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKSGGVICEKHWPMDEHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTPEKNMPEKEIPEKEE"
     gene            complement(4738..5637)
                     /locus_tag="J8S10_001417"
     CDS             complement(4738..5637)
                     /locus_tag="J8S10_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HAZ9630005.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            complement(5652..6053)
                     /locus_tag="J8S10_001418"
     CDS             complement(5652..6053)
                     /locus_tag="J8S10_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HAZ9630006.1"
                     /translation="MPMDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFG
                     ILALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKD
                     MAAGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            complement(6031..6507)
                     /gene="ybeY"
                     /locus_tag="J8S10_001419"
     CDS             complement(6031..6507)
                     /gene="ybeY"
                     /locus_tag="J8S10_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HAZ9630007.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            complement(6524..8716)
                     /locus_tag="J8S10_001420"
     CDS             complement(6524..8716)
                     /locus_tag="J8S10_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HAZ9630008.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIVCGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQRRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDTINKSYNDKVDKAKEDENIPKPTTEERIATLKKNFENVNAENVAFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEDQIQYLNVTTEQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSIV
                     LMKFFQLFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTIILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGD
                     ATTWLMLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICKQHHGTTLMRYFYIKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEEQEE"
     gene            complement(8740..9711)
                     /locus_tag="J8S10_001421"
     CDS             complement(8740..9711)
                     /locus_tag="J8S10_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HAZ9630009.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            10417..11796
                     /gene="brnQ"
                     /locus_tag="J8S10_001422"
     CDS             10417..11796
                     /gene="brnQ"
                     /locus_tag="J8S10_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HAZ9630010.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGANWV
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYNSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFHPMGNLNQSAADTYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKTPFVYQVTMLFAAVPAVLDM
                     LANSPALVSQQRVVASMLEFYHHHVPFAALGLGWMVPTLLGYAGSLLFYYAYRLSGYK
                     QEANELPEE"
     gene            complement(11952..12398)
                     /locus_tag="J8S10_001423"
     CDS             complement(11952..12398)
                     /locus_tag="J8S10_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HAZ9630011.1"
                     /translation="MSLLSRLNDDMKTAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(12425..12601)
                     /locus_tag="J8S10_001424"
     CDS             complement(12425..12601)
                     /locus_tag="J8S10_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HAZ9630012.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            complement(12763..13191)
                     /locus_tag="J8S10_001425"
     CDS             complement(12763..13191)
                     /locus_tag="J8S10_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAZ9630013.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            13283..14143
                     /locus_tag="J8S10_001426"
     CDS             13283..14143
                     /locus_tag="J8S10_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HAZ9630014.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPSVEFNLFRRT
                     FVTDEKTLMQALQDALEEKALVLHTLINQELIEMTRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEETD"
     gene            complement(14227..14520)
                     /locus_tag="J8S10_001427"
     CDS             complement(14227..14520)
                     /locus_tag="J8S10_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HAZ9630015.1"
                     /translation="MPDTQKTKVEKVSQLFKMLSDPTRLKILLYLKDGEQNVTAIIQA
                     VEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHVLDILNQTLKHVEHQ"
     gene            complement(14593..16320)
                     /locus_tag="J8S10_001428"
     CDS             complement(14593..16320)
                     /locus_tag="J8S10_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HAZ9630016.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAEHSGLITIIGEEVDAAYLEEIKAV
                     TIDHELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPNGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYYAEKTISVTMSGQEGSAKISALMEKFREEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGNSSEDAAEKVAAYE
                     TIIQKMTEE"
     gene            complement(16533..17459)
                     /gene="trxB"
                     /locus_tag="J8S10_001429"
     CDS             complement(16533..17459)
                     /gene="trxB"
                     /locus_tag="J8S10_001429"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HAZ9630017.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYEGVSRFGTENAYGIVQDIKDHGSHKEVICEDKTYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNIPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            complement(17604..19037)
                     /gene="ascB"
                     /locus_tag="J8S10_001430"
     CDS             complement(17604..19037)
                     /gene="ascB"
                     /locus_tag="J8S10_001430"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAZ9630018.1"
                     /translation="MGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGEDRFPV
                     ITGKKKMFEFDENHFYPAKIAIDMYHHYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     KEPNESGLKFYEDVFKECQKYGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQIKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIKMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFASV
                     KNPYLEASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNEGNG
                     TLARSKKKSFNWYKKVIDSNGENLSND"
     gene            complement(19037..20440)
                     /locus_tag="J8S10_001431"
     CDS             complement(19037..20440)
                     /locus_tag="J8S10_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAZ9630019.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPTMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMNELFIAHQQYLPQFKETISRLKAEGIEVQ
                     DELARELSSNTHVMEEV"
     gene            20670..21572
                     /locus_tag="J8S10_001432"
     CDS             20670..21572
                     /locus_tag="J8S10_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAZ9630020.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSSMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVD"
     gene            complement(21613..23499)
                     /locus_tag="J8S10_001433"
     CDS             complement(21613..23499)
                     /locus_tag="J8S10_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAZ9630021.1"
                     /translation="MGKYQELASKIVENVGGKENINGLTHCITRLRFKLKNEEKANDE
                     ILKNMDGVVTVMRAGGQYQVVIGNHVPVVFEEVIKAGNLTFDEAVSTEKMRPFDMLID
                     GISGCFQPFLAILAAGGMIRGLTALLVFLGAFDRGSGTFVMFDNIGDSVFQFMPVIIG
                     LTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSGTIFEAPIYQTVFG
                     IPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFFTVLITMPLGFLLV
                     GPAFTFATDILMAGFETLLALSPVIYGAIVGFFWQILVMFGLHWAIVPMGLMQFSVNG
                     WQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVGITEPAIYGFTLPR
                     KKIFIFTCVGGALGGAYSGLMNLTSWNPGGLGIFTIPNYIRPDGDLTDVINVLIGIAI
                     AMVVSFALTFFFWKEEAGETDDRQKRSGKEIVKTPIQGQIAPLNAAKDAAFAQGTLGR
                     GILIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSEAGLELLIHVGLDTVQLEGKYFESL
                     VQQGERVKQGDLLLRFDKKKIEEEGYSLETPVIVTNYTDYLDILENQGETVGPDDALI
                     TALT"
     gene            complement(23596..24447)
                     /locus_tag="J8S10_001434"
     CDS             complement(23596..24447)
                     /locus_tag="J8S10_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAZ9630022.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVQLNDSVYIALTDHLY
                     TAIERHKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQDNTYLFTTTIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GEKSEVGEVSEELYQVIQKKYKDTFGCVEKIADFLAEIFNYQMSTDEKMYLTIHIARL
                     VHENRCK"
     gene            complement(24905..26689)
                     /locus_tag="J8S10_001435"
     CDS             complement(24905..26689)
                     /locus_tag="J8S10_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9630023.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYVRVRLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFIAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     ALTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSTFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQAITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPTITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLTKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGV"
     gene            complement(26689..28440)
                     /locus_tag="J8S10_001436"
     CDS             complement(26689..28440)
                     /locus_tag="J8S10_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAZ9630024.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGIFSLFAVALVQLAPPKVIGIIID
                     EIADKNLSIKIISWWILLLILAALLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGCSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     RMWEKQKLEAKIEGGEA"
     gene            complement(28582..28806)
                     /locus_tag="J8S10_001437"
     CDS             complement(28582..28806)
                     /locus_tag="J8S10_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HAZ9630025.1"
                     /translation="MVSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            29057..30643
                     /locus_tag="J8S10_001438"
     CDS             29057..30643
                     /locus_tag="J8S10_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HAZ9630026.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQDEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHTALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFVVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADQIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQRLQETIEEIE"
BASE COUNT         8675 a         6650 c         5522 g        10167 t
ORIGIN      
        1 ttttacactc tctgattgac gtcataaaaa gtagctttga attcataatc gtttatataa
       61 cgattaatag aaaacaatat agtatttagt gttcatacaa tgattctaag atcattttga
      121 attaatcagt cttatagttg atttctaaat tgtcatatat tattaaaaat ttttgccatt
      181 taaaaagaaa agcgacagtt taccaataaa tttcaactga attatctaaa agtagatcag
      241 ttagtttaga taattcagtt gaaattgacc gactcaaatt acttgtataa tacctaggaa
      301 aaaattaact agcaccacgg gtatagttat ttatatttat aacaaataaa ccagagaaat
      361 agcctatttt gtgcctattc tctggtttat ttacatatta gaaattattt tgtgatgatt
      421 tgatctaaac ttgctagcga caaagccatg gcagcaattt gacttaattg cgttaatcgg
      481 ttcttacgta ctgctggttc ttctgccatg accatcgtct gatcaaaata attttcgatc
      541 agtgggcgaa ggcttacaag ctgatcataa ttttcgttga tcgtttggtc agcaaagctt
      601 tttttcattg cctctactgc tttgtgcagt tctttctccg cttcattttc gaacagttca
      661 gggtctactt ctgattgttt ttcaagctcc gcttttttcg ctaagttcac gacacgtgtc
      721 aaagcttcca tcgatggttt gaagtcttca tctgcaagat gctgcttgaa caattgtgct
      781 gctgcaaata cttttgtcag atctttttgt tctgcattca aaacagcttc gatgacatca
      841 tgacgaatat tcttcgttgt caataattgg cgcagacggc ctttgataaa gtcgatcacc
      901 tgttgttgcc cttctgataa accaatgccg aaacgatccg tatctttact gataacatca
      961 ctaatcgttt cttgcagaac agacaaagga aaggcccatt ttttcgattc gatgatccga
     1021 acgacaccgt atgcttggcg acgtaaggca taaggatcgt ttgacccgct tggaatcatc
     1081 ccaactgcaa agaaagaaaa aatgctatct aatttatctg caatcgctaa aacagaacct
     1141 actgtagact gaggtagctc tccttcactg gatataggca tgtaatgctc acgaatcgct
     1201 gttgctacag caggtttctc gcctttcagc agagcatatt tttcgcccat gatcccttgt
     1261 agttcaggaa attcccctac catgttggtt actagatcaa atttatagat ttcagcagct
     1321 cgttgcagat ccatcaattc ttcctcagat agtcctactt gttcgccaat gatacgggca
     1381 atgacttgta cccgctgcat tttctcatag atactaccga ttttttcatg gaaagtaaca
     1441 gtttttagtt tttcaacgta ttggtcgatt gaagctttct tgtcttcatt ataaaagaat
     1501 tccgcatctt ctaaacgagc cgtcaatact ttttgattgc ctcgaaccac attttccaat
     1561 tttacccgat caccattacg agcagaaata aaatgaggaa gcagcatacc ttgatcgttc
     1621 cgtacctcga aataacgttg atgttctttc atagaagtga ctagtacttc ttcaggaaca
     1681 gaaagatatt tttcttcgaa gtcgccagaa aagacagttg gatattcgac taaattgttg
     1741 acttcttcta gtaaatcttc gtctagatca ataacccagt gatttttttc ggctaattca
     1801 tttgcttgtg taacgatcat ttcttgtctt ttttgcggtg aagcaataac gaattgttca
     1861 ttcaattttt cttcatattc ttttgcatgc gcaaatgtca catcttcgcc taagaaacga
     1921 tgtcctcgag aggctctgcc tgttttgaca tctaagatct caaacgggat tacttcgtca
     1981 tctaacaatg ccacgatcca gtgaataggg cggatatatt caaaatcgta ttctgcccaa
     2041 tgcatcgtta ctgggaaagt gaggctttta atgacatctg ctaaacctgt caatacttct
     2101 ttcgcttctt tgccgtgagt gtatttcgtt acatagacat attccacgcc ttttaattct
     2161 ctaaaagtga tagcatctgt cgtcagacct tgtccgcgga caaatccttc agctgctttc
     2221 gtccagtttc catctgcgtc caaagcaatt tttttggctg gtcctttgac ttcttcttca
     2281 ctgtctgctt gacgttctgg aatgtttgtt actttgattg ctaagcggcg cggtgtagaa
     2341 aacgtttcga tcgtatcata agtcaattgg ttttcatcta aaaattttgc tgttttttct
     2401 tctaattgtt tcatgcttgg tgtgacaaca tgagcaggca tttcttccag cccgatttca
     2461 agtaataagt cttttgccat cttattcagc ctccttcatg ttttctggat ttgctgtgtt
     2521 tttattcaat aaagggaatc ctaatttttc gcgttctgcc acaaagattt tggctacagc
     2581 acgagccatg ttgcggatac gggaaagata acctgctcgt tctgttacgg atactgcacc
     2641 gcgagcatct aataaattga atgtatggct gcatttcaaa atataatcat acgctggatg
     2701 aacaagattt tcatcgatac agcgtttagc ttctttttca aaacggtcaa agttgcttag
     2761 tagcaagtct tggtcactta cttcaaaaga atatttggaa tgttcatatt ctggttgttt
     2821 gaagatctcg ccatatttca caccatcagc ccattccaga tcatagacac tttcaacttc
     2881 ttgaatatat gaagcaagac gttctagtcc ataagtgatc tcagaagtaa ctggtttaca
     2941 aggtagtcct ccgacttgct ggaagtacgt gaattgtgtg atctccatcc catcaagcca
     3001 tacttcccaa cccacaccgg cacaccccat cgatgggttc tcccagttgt cttcaacaaa
     3061 acgaatatcg tgttctaatg gatcaattcc taaaagacgc aagctttcta aataaagctc
     3121 ttggatattt tcaggtgaag gtttcattac gacttgaaat tgatgatgct gatacaaacg
     3181 gtttgggttt tctccataac gcccgtcagc tggtcggcgg gatggctcta cataagcagc
     3241 attccatggt tccggtccga ttgcccgtaa gaatgtatat gggctcatcg tacctgctcc
     3301 tttttctgtg tcataagctt gcatcagcat gcagccgttt gatgaccaaa atttttgtaa
     3361 tgttaaaatc atatcttgga cggtcaattt tttactcatc tgttttgccc ctttcaattt
     3421 ttaagcgttg ctgtcaataa gaatacagga aagaaaacga caaaaagtcc ctatgtctga
     3481 ttacagacat agggacgaat aatttcgcgg ttccacccta cttccgaata aagattcggc
     3541 agcttcattt atcgtactcg caagtgcctc ttcaaaaatc gtttgggtcc ggcttccact
     3601 ctcccgaact cgctaaacca cgtgtttttt actgatcttg gtcaatgtac gtattcattt
     3661 tgcagttttc ttgtttatat aatagatcct ctcagtgaac gatctattta atctacggtt
     3721 aataatagac ggaagtccct gtatttgtca aatagttttg atttttttgt tgtatctttc
     3781 atttattctt ctttttcagg tatctctttt tcaggcatat ttttctctgg cgtctttaat
     3841 acgtgtgccc aagacttcat ttgatcaatg aactttttgc tttttagatg aataccgaca
     3901 tattcatcat acaactggtc aatgaggtca cggattgcct gcttcgtttc ttctttcaag
     3961 tggattccac tgatcttatc ataagaaata gccgaaaaca ttcgaacgaa ataaacagcg
     4021 cgaggatctg catgataacg gtgttcgtcc attggccagt gtttctcgca tatcacaccg
     4081 ccagatttgg aagaatagtc aaattttcct tttgtttccc cgcatacgac acagtgcgtc
     4141 caaattggcg cgattccgaa gcgttgcagt atttgaactt caaagatatt cgtgatgatt
     4201 tctgcatcat ctccttgatc catccgctgc agagcttgtt gcgtaaattg gaataaatgc
     4261 gggtcatatt gatgatcttc gattgctgca tctactagat ttagcaaata ggtaccataa
     4321 ccgctcaaaa agatatcttc ttggatgttc cgaaacgcat ggacgtcttt gacactgctt
     4381 aaaaacgaca aaccttcact tcgaaaatta ccgatataga ctgcttcggt aaaggggagc
     4441 aaagccggag ctaatggctg attttgccga tggattcctt tgatataaaa catcattttg
     4501 ccagaagatt ccgtaaagat tttgactaat ttatcttttt ctttgtaatt acggctagat
     4561 aaaatcaagc ctttcgattc tgcaagctgg ctcatattct ccctcctaaa aaataaatct
     4621 ggaaaagcag attctgccga tccagattat ttatgtttcg atcttccgcc gtttttctca
     4681 acgtgcggat ttttatccag tttatttcta tacttaacct ataagaagtt cagaatatca
     4741 gtattcgtct tttcggtagc caaagtcttg cagatagact tttttgtctc gccagtcttt
     4801 ttggactttg acccaaagtt ctagaaatac tttgtctcct aaaagatttt cgatatcctt
     4861 tcttgctttc gttcctactt gcttcagcat ttttccgcct ttgccgataa tgattccttt
     4921 ttggctatct ctttcgacga tgatcgtggc ctggatatgg attttatcat tctcgtttcg
     4981 cttcatcgaa tcaacaacga ctgcgacaga atgaggcact tcgtctcgtg ttaaaaacaa
     5041 gactttctca cggatcaatt cagaaacgat aaagtattca ggatgatcag tcacttgatc
     5101 atctggaaaa tattgtgggc cctctggcat ttcactgact aatacatcca ttaagcgttc
     5161 gacattgttt ccttctgtag cagagatcgg aatcacttgt gcaaaaggca tctgcgtcga
     5221 ataatcttcg atgattccca gcaactcgtc tggatggatc ttatcgattt tattgataat
     5281 cagataaact ggagaatgca cgttttttag acgttcaata ataaaatcgt ctccccggcc
     5341 gcgtttttga tcagcactga tcataaataa gactgcatcc acttctttca acgcactgta
     5401 agctgcttct accataaaat ctcctagacg atgctttggt ttatggattc ctggtgtatc
     5461 gataaaaatc agctgagctt ctggtgtagt atatactcct tggattttat ttctagttgt
     5521 ctgtgccttg tcactcataa tggcaatttt ttgacccacg attcggttca ataatgtgga
     5581 ttttcctaca ttcgggcggc cgacgattgc gacaaaccct gatttatgtt ctggcatata
     5641 cgttctcctt tttaattaaa caacaaatga tatattttag ggacaaataa aatcaaccca
     5701 atgatgacag caaaacaagc ggtcactaaa actgctccag ctgccatatc tttgattttt
     5761 ttcccaatcg gatgaaaatg aaaatccgta aacatgtcca ctacattttc aaaaacagta
     5821 ttgatgatct ctactatcca aacgagaaaa acagctaaaa gcagccataa ccactctatc
     5881 cgatcaagct ggaaaatcac gcccataaat aaagcaagga taccgaacgc aacatgtttc
     5941 ctcatattgc gttcttcctc aaaaacggtt ttgactcctt ggacagcaaa ttccacagac
     6001 atcaggaaat gtttgttttt ctctacgttt ttatcttttg agtccatagg catccaagat
     6061 ctctttctgt aaaccaaaca tttctttctc atcttctggt gtcatatggt catacccgtt
     6121 gatatgcaag aatccatgta ccgctaaaaa gccaagttcc cgatcatatg aatggccgta
     6181 agcttctgct tgttcagcag cacgttcaat agaaatcatg atgtctccta gtacacgagg
     6241 caaaggattc tctccatctt caaaaatcac tgggatttcg tcttcgcctt cttcttccag
     6301 agcaaaactg atgacgtctg tcggtgcatc ttttccacgg taatcacgat tgattacttg
     6361 gattgccgca ttgtccatga aagtaacaga catttctgtt tcctctggca gctttaaata
     6421 agatgctgca aattgcagca agtcatcgat ttctttcatt ttctcttctg agacttggtt
     6481 tgtttcatcc ataaaggtaa tatccattat acatcgcttc tttctattct tcttgttctt
     6541 cctttatctt ctcaacttct gttttcattt taggatattt gatccgagaa tggaaggtgc
     6601 tacttaaacc gctgatcaat gatttttcca cttttcggat ttctttcaag gtcagtccac
     6661 tatcgtctaa ttgaccatcg gaaatacgct cttcgataag attatggaca aaactttcga
     6721 ttttttcgct cgtcggatga tccattgccc gtactgcagc ctcacaactg tcagcaatat
     6781 tgacgatccc tgcttcacga ctttgcggtt ttggtccagg ataacggaat tgctcttctg
     6841 ttacttccgg attgcgttct ttcgctttga tgtagaaata acgcattagc gtggttccat
     6901 gatgctgttt gcaaatatcg atcaccattt gcggcatatt ataatcttcc aatattttgg
     6961 ctccatctgt cacatgtcca aagataatat gtttactgtc ttctggcaat aagaaattgt
     7021 gcgggttttc cgctcctgaa ggcaagttct caacgaaaaa gctagcatgt ttgatcttgc
     7081 cgatatcatg ataatagcaa gctactcgag ttagcaaaga acgtccgccg atttctgcta
     7141 cagcgttagc acttagatta gctaccatca tactatgatg ataagtacct ggcgcttctt
     7201 ccagcaactg tttcaataaa ggatgatttg gattgctgag ttcatttaat acaattacac
     7261 tgtcatcatt gaccatcaat tcaatatatg ggtgtagacc gatcgtcagc aagaatgaga
     7321 agagtgcacc agtgaacccg cagacaagca ttaaccaagt cgttgcatca ccaaagctca
     7381 ttccttgata gacgatcaaa atgacatcca tcatcacagg aaaaataatg acccacatgg
     7441 cagcagataa tccttgttct gagatccgtt tgcgtctgac aatcgttgcc atgagcccag
     7501 agaaaacata agacatcaag ataatcgtta gaaagttcgt gccaatcgaa tcataaaaaa
     7561 tgaaaagtgc agatactgct tggaaaatac cagccatgat ccctgctctt cggttcaaga
     7621 aaaagcttaa aacaagtggt gcaaaagcag cgggataaaa cagcgggata taagtagctt
     7681 gttccgtttg gaataattgg aaaaatttca tcagcactat gctgactgac atagctgtca
     7741 catagaaaag cacgtatttt gttctttctc ctgcattttg gaattgaagt gaattataaa
     7801 tcagtacgcc gatttgaagc aaaacagcta aaaccatggc aatgagtggg aaaatcgaag
     7861 tcgtttgatt cgtcaatcct agtaattcca attttttcat cgctgaagca tcaatttgat
     7921 ttccttcgcg aacaatgatt tctccttgga agatcatcac tggttgtaca gcttctcgtg
     7981 cagattgttt taattcttct gtctttttct cattcaatac atcattgact acaatgcctt
     8041 gatccactaa gtagcgaatc atttgttgct gctctgttgt gacattcaaa tactgaatct
     8101 gatcttctgc ttcttgttta aaagcttcca attcgctttc acgaacttgt ttactcatct
     8161 gttcgtcaat gagcttcaaa ctttcatccc taaccgtgtg aatttccgtt tcagtcattt
     8221 caaatatcgt cgaataaaaa ttgttcggca gtttttggta aaacgcaacg ttttctgcat
     8281 tcacgttttc aaaatttttc ttcagtgtag caatccgctc ttctgtagta ggtttcggga
     8341 tattttcatc ttccttcgcc ttatctacct tgtcattata agatttgttg atggtatcat
     8401 tcgtcttatc gatcaattcg aataattgct tgatccgatt gttctggtca tctgccagat
     8461 ctttttgata agtatattct ggagtcactg cttctgctgc cagttttctt ctttgttcgg
     8521 tttcttccgt gttctcgatc gttttattcg cacggatact ctcttctgct acttggcctt
     8581 ctctgaaatc attggccttt tgtttgacac tactaaatgt aacgccgcag acaatgataa
     8641 aaaacaagaa cagaaggaaa ggcaatgctg cctttccgag tttttcttgt agtttctgca
     8701 gtgttttatt caacatgtgc ttatcctcct aagcaaagct tattcttgat gaagatccgc
     8761 cttttcataa gctttgatga tttcggcaac tacagggtgc cgaacaacgt cacttgcttc
     8821 aaaattaaca aaatcgattt ttttgatttg ctttagtgtt cgttctgcat gaacaagacc
     8881 acttgtcgtc cctcgaggca agtctatctg acttgtatcc ccattgacaa tcatttttga
     8941 ttgataaccg agacgggtca agaacatttt catctgagcg actgtcgtgt tttgtgcttc
     9001 gtccaagata acgaatgcat catccaatgt ccgcccccgc atgtaagcta atggtgcgat
     9061 ttcgattacg cctcgttcca tcaatcggtt cgtatgatcc aatccaaaaa tttggtataa
     9121 agcatcataa acaggccgca gataaggatc cactttttct ttcagatccc cgggtagaaa
     9181 gcctaggttt tcccctgcct ctacagcggg ccgcgtcaaa atgatttttt gcacttcgcc
     9241 tttttttagg gcagcaattg ctaatactac ggcaagaaac gttttccctg ttccggctgg
     9301 ccctacacca aatacgatgt catgtttggc taccgattca acgtatttct tttgaccgct
     9361 gttttttacc cgtataggtt ttccattacg gtctttgacg atctcttcct catacatctc
     9421 aacaaaataa tctaatgtac ctttttgccc cattttcaat gccgtcacga catctggtgt
     9481 acttacgtgg attcctcgtt tgatcaattc ctgtaatgtc cgaatgactg aggcagccaa
     9541 ggaaatctgg gattgttcac caatgatctg aatgatttct ccacgtgtat ggatggttgt
     9601 ttccgttgtt tcctcgatca gttttatatg cttgtcgtgt gcacctaaaa gcatgctgac
     9661 atcatcagca gctgtcaatc taatctctaa agaactagac tcttccgtca aaaatagaca
     9721 tccccttttt ttcgattcat tctttcctat tttaccatac tcagaagaaa ctatatagca
     9781 aataagaaaa ggttgtaaaa gagtcgttta accatacgta ccaagaaacg ttaaaaaata
     9841 gctgtttcca ttcgctaaag gtctcgtttt gataaaaaga atctgagaat gtaagttata
     9901 tgaaagtgga gaacaaaata ttccgtttca ttcagaggta ttctctaggt atttttcttg
     9961 tttcaaaaaa agaaaacaaa atagttaaaa tattcttgca tttcaaaaaa aacaggtgta
    10021 ttattacgtc aacaaataaa catacagcaa agcgtcgagg aaaacagtag gctattcaac
    10081 gatttattcc cagtgagtca tgtaagtgag aaatgacaat aaatcgaata gacgaacatc
    10141 atttccgagt caatgtcgaa aacgtagatc attgtggctg cctccattat caggctagcg
    10201 gataacttta tcaaaaagcg tccgtgaatg aagaagcttt tttaagcgaa aaaaggtggt
    10261 accgttctag aatctagagc ccttttccca agtggaaaag ggcttttttt tatattttaa
    10321 ggtggtggtt ttcatggaat ctgatattag tggcattact aattgctgca acgtttatat
    10381 cgtcaatcaa aatgataatt attggaggaa aaatttatgg aagaaacaaa aacttattca
    10441 tggaaacaac tattgatggt cagttcactt atcttcggga tgtttttcgg gtcaggtaat
    10501 ctaatctttc ctgtccactt aggtcaaatg gctggcgcaa actgggtcag tgctggcgta
    10561 ggatttgcca tctcaggcgc tcttttccca ttactagcta tcttagctgt agtagtgaca
    10621 aaaagtgatg gtctgtatga cttagctaaa cctgtcggaa aatggtatgc tgccttgttc
    10681 ttaatccttg ttcatttgac gatcggacca tttttcggta caccacggac agctgctact
    10741 gcttttgaaa tggctgctaa accatttttg cctgaaaaat ataattcatt aggtatgttt
    10801 ttattctctg ctcttttctt tttacttgct tatttcctta ctgtccatcc cacacggttg
    10861 gtcaaatacg tcggaaagta tctaaactcc ttgtttcttg cattattagc aatcattttt
    10921 gtcgtttctt tattccaccc aatgggaaat ctaaatcaat ctgctgcaga tacttaccaa
    10981 acaaacgctt taacaaatgg tgtcctagaa ggttataaca cggttgatgc agtagccttg
    11041 cttgccttaa gtgtcacttt tgtccatgca gtccgtgacc ttggtttcaa agataaaaaa
    11101 gtcacagaat taacagcaaa agctggtagc ctgagcgttg cgctagaagt catgatctat
    11161 tttggtcttg ttcttctcgg tgcgatgagt ttgaataaga tgtctttatc agaaaatggc
    11221 ggaactgcac tttctcagat cactaatttt tatttaggta acttcggcgc tagcttctta
    11281 ggagtgatgg tcacattagg tgtcttcact accgctatgg gactcgttgt ttcttttgca
    11341 caagatttcc ataaactgtt ccctaaagtc agttatatga catggctgcg gttaacgact
    11401 ttcgtctctt ttgtcgttgc aaatgctggt ttggacaata tcatccaatg gtctttacca
    11461 gtattgatgc ttttgtatcc attgtcgctt gcgttgattt tgctttcctt aacagcaaaa
    11521 tttttccaaa agacaccatt tgtctatcaa gtaacgatgt tgtttgctgc tgttcccgcc
    11581 gtattggata tgctggcaaa ttcgcctgct ttagtgagtc aacaaagagt tgtagcaagc
    11641 atgctcgaat tttatcatca tcacgttcct tttgctgcat tgggacttgg ctggatggtc
    11701 ccaacgttac ttgggtatgc tggcagctta ctcttctatt acgcctatcg cctatcaggg
    11761 tataaacaag aagcaaatga actaccagaa gaataaccag atcaaacaca atttaacata
    11821 agaaatatta aacaggaaaa aaacagctag atgaaagaat cctattcttt cgtctagcta
    11881 ttttttagat ctctttttta cgagcacaaa aaaactgcgg acaatgattg tccgcagttt
    11941 aaatgataaa attaagattg taatagttct ttcacaatgg catttacttg gtttccatct
    12001 gcttttcctt tgactttagg catgatcgca cccatgactt tgccaaattc tttcattgat
    12061 gaagcaccag tttgcgtgat tgcttcttga acaagttgtc gaatttcttc gtcggaaagt
    12121 tgttccggca tgtatttttc gactatcaca atttcacttt ttactttttc agctaaatcg
    12181 tcacgtcctg cttcttcaaa ctcatgcaaa gaatcacgtc gctgtttcat ttcgcgagac
    12241 aacaccgtta attcttcttc ttctgtcaag tcgtgacctt ctttaatctg ctcgttttgt
    12301 atagatgact tgatcattcg gatgacttgt aaagattcct tatctttcgc tttcatcgct
    12361 gttttcatgt catcgtttaa tctacttagt agtgacacac taccaactcc aattcatcac
    12421 agaactagaa ttttttgcgt tttctagctg cttcagattt tttcttgcgt cttacacttg
    12481 gtttttcgta gaattcacgt ttacgagatt cttgtaaagt acccgctttt gacacggaac
    12541 gtttgaagcg acgaagagca tcgtcaagtg attcgttttt gcgaacgact gtttttgaca
    12601 tgttaattcc ctccctccga gcttaaaaag taaccgtaat tgttattgaa atatatctca
    12661 aaaaacaaga ctgtcctgta aatattatat ctaatgctgt tttgaccgtc aaggaaatct
    12721 tgcttttttt taaaattatc aaatgttatt ttatttaaat ccttattgac aattttcaca
    12781 tcttccgaaa atctcgaatc tatgcccttc gatcgtacat ccaccgagct gttcttcgaa
    12841 ataattcatt ggacacatat ggatttcttt cgttgttccg cacaccgtac agataaagtg
    12901 atggtgatgg ccgatttccc cttgacagca atgaaaacga aacttcatct ctccatttaa
    12961 atcggtttct tccagtaaat cgatttctgc aaaatcatgg agatttcgat aaatcgtatc
    13021 gtaacttact cctttgaatt cctgattcat atagtcaaaa acttctttag cggatacgta
    13081 gcgattgcgc ttcactaaat aagttaacaa tgcttctctt tttttagtat atttaaaacc
    13141 gttatttttc aatgtttcta gtgattgttc gatcaacgtc tgttttttca tgacttattc
    13201 ctccaaatca aaatgattac gaagtacaca ttctagagta tggtataata aacataaaaa
    13261 aaatgcaagt gaggttttat ccatgtcttc cgattctaca gaaatcgtta ctttttttgt
    13321 catctccgac tctgctggag aaactgcgac aaaactagcg caagccacta tggcccaata
    13381 tcctagcgtt gagttcaatt tattccgcag aacatttgtg acagatgaga aaacattgat
    13441 gcaggcactg caagatgcac tagaagaaaa agctcttgtc ctgcacacat tgatcaatca
    13501 agaattgatc gagatgacgc gttctttttg tgaagaacat caattattta gttttgatgt
    13561 gatgactccg ccgatatcag aaatcgagcg cttaactggt atcaagccca ttcggcaacc
    13621 tggcgccctt catttattga atgagaacta tttcaaacgg atcaaagcaa tggaatttgc
    13681 tgtaaaatac gatgacggga aagatcctcg tgggtttcta gaagcagatg tcgttttgct
    13741 aggcgtatcc cgaacttcca aaacgccttt gagcttgttt ttagctaaca aaaatttaaa
    13801 agttgccaat ctacctttga tcccacaagc acatattccc aaacagcttt gggagatcga
    13861 tcctaaaaaa atcgtgggac tgacgaataa cccagatatt ttaaacaata tccgtaaaga
    13921 acggatgcgc tcttacggat taaatcctga tactgcttat tccgatatcg aaaaaatacg
    13981 agctgaactc gattttgcga atgatcttta tgaaaaattg ggctgcgtag taatcaatgt
    14041 cgcttcttta tctattgaag aaacagcttc gcttattttg aatgctttag acctagaaga
    14101 ccatagttat tatggaactg aaaccaccga agaaacagac taacaatttt tctttaaaaa
    14161 aactggactg tgtcagcgaa gaagattcgt tgacacagtc cagtttgtct ctatttgcac
    14221 ctatcgttat tgatgttcca catgtttgag tgtctggttc aaaatatcca gtacgtgaga
    14281 atcatcaaga ctatacaaaa tcgcttttcc ctcacgatgg gacttgacga catggttttc
    14341 tcttaataaa cgcagttgat gcgatacagc agattgttcc atttccactg cttggatgat
    14401 tgctgtcaca ttttgttccc cgtctttcag atacagcaga attttgagac gagtggggtc
    14461 actcaacatt ttgaatagtt ggctgacttt ctctactttt gttttttgcg tgtctggcaa
    14521 tccattcacc tccaacttga aaaaagactg acttctaaag tttaccactt tttccatcag
    14581 tctcaagttt ttttattctt ctgtcatctt ttggataatc gtttcataag cggctacttt
    14641 ttcagctgcg tcttctgaag agtttccttt tacaccgata taaaatttga ttttcggctc
    14701 agttcctgaa ggacggatag cgatccagcc attttcttcc agcgtatact tcaatacgtc
    14761 agatggcggt gtcgttagtt tttctacgtt tccttcacgg tctgttctcg tcaactcttt
    14821 gaagtcttct gtttggatga cttttgctcc ggcaaattct gttggtgctt cttcacggaa
    14881 tttttccatc aaagcagaga ttttcgcaga accttcttgt ccgctcattg tcacagaaat
    14941 cgttttttct gcgtagtagc cataggtttc aaaaatcgtt tgcaagccat catacaacgt
    15001 tttgccttgt tttttatagt aagctgctac ttctgctaat aagagcaatg cttggatcgc
    15061 gtctttgtcg cgaacgaaag gtttaactaa ataaccgtaa ctttcttcga atccgaacat
    15121 aaaagtatgg gaatgatctt cttcaaattg ttgaattttt tcagcaatga atttgaatcc
    15181 tgtcaataca ttgaacatgg tagccccata gtgttccgca attgctgtag gtaattcgct
    15241 agaaacgatc gatttcaata ccgctgcgtt ttcaggtaaa gtgcctcgcg attggtgtgc
    15301 ttccaaaata tattgagcaa acagtgctcc gatttggttt ccggtcaata cttcatagga
    15361 gccatttggc aaacgaacgg ctgcacctaa acggtctgca tcaggatctg ttgcaatcag
    15421 caaatcagcg ccttctttct cgccaagtcg tatcgcatac tcaaaagcag agtgttcttc
    15481 tggatttggt gatttgactg tagtgaaatc tgggtctgcg acagcttgtt ctggaactag
    15541 tacgaattgt tcgaatccag cttgtttcaa cgcacgttcg cccaacattt ttcctgttcc
    15601 gtgaagtggt gtgtacacaa gtttcaaatc tttccccatt gtttccacca attcatgatc
    15661 aatcgttact gctttgattt cttctagata agcggcatcc acttcttctc cgatgatcgt
    15721 gatcaatccg ctatgttcag cttcttcgtc agataatact tcaactttta acggattgct
    15781 gacttcacgg acatatttcg tcaatgcatc tgcgtctgca ggaggcattt gtcccccatc
    15841 ttctccgtag actttatatc cgttgtaagc tgctggattg tgggatgcgg ttaccatgat
    15901 tcccgcaaac gtcttcaaat gacggactgc aaaagaaagc tctggtgttg gacgtagact
    15961 ttcgaataca taagatggga tattgtgatg tgctaatgtt ttggctgctt ccatggcaaa
    16021 ttctggtgat tgatggcgtg agtcataagc gatagcgaca cctcggcgtt ttgtttcttc
    16081 gccttgtgta tccatgaaac gtgcaagtcc ttctgttgct tgtcttaccg tatagatgtt
    16141 cattcgattg atcccaggcc ctaagattcc ccgcatgcct gcagtaccga attccaacgg
    16201 tgcataaaaa gcatcttcaa gtttttcagg atcttcaccc agatcattta attgtttttt
    16261 taagttttct tctaaatttt cttcatgtac ccattgttca tacacttgtt cccaagacat
    16321 gaaaataaca cctctttctg aaatatggtt cttaataagt atagcattca cttattagat
    16381 atgaaagtat gaggaccaaa aaacgcttaa atcaagaaag gattctttta tcaagcacgg
    16441 ttgcaagtat tcgcataaat cggattcagt agatttcacg cgaaaaaaaa gagtaaaaga
    16501 acaattaaac cgttcttcca ctctttttaa acttatgcag ttgtttcttc taaagattcc
    16561 aagtatttat acacttgttg tccagcgatc ccaccatcac caacagcagt agtgatttgt
    16621 cgcaaatctt tttcacgaac atctccgatg gcaaaaacgc ctggtatatt cgtcttcatt
    16681 tcgttgtctg ttggaatcca gccagcttcg ttcgtcaacc ctgcttctct aaatggtgca
    16741 gttaatggat ccagtccaac atagatgaat actccgtctg ctgccaaatc aaactcattg
    16801 ccggttttga cattacgtgc tttcacacct gtcactacca tttcattccc aacgatttcg
    16861 tcaacgactg tatcccacat aaaggaaatt ttttcattcg caaatgcacg gtcttggatg
    16921 atcttttgtg cacgtaattc atctctacgg tggacgatga ctacttcaga agcaaattgt
    16981 gtcaaataga tggcttcttc tactgctgag tctcctcctc cgatcactac tagacgtttg
    17041 ttacggaaaa acgcaccatc acaaactgca cagtaagaaa cgccacgtcc agcaaattct
    17101 tcctcgccag gtacgcctaa tttacggtgg atacagcctg ttgcgataat gactgttttt
    17161 ccttcgtaag ttttatcttc acaaataact tctttgtggc tgccgtgatc cttgatatct
    17221 tgcacgattc cataagcatt ttctgtccca aatcttgaaa caccttcata catcttataa
    17281 gctagatcag gacccattat tgaatcgaaa ccaggatagt tttcgatttc tgccgtattg
    17341 ttcatttggc cgccaggggc gccttgttcg atcatcaata cggataagtt tgaacgtgaa
    17401 gcatataaag cagcagtcat cccagcagga cctgcgccaa taacgattac atcatacata
    17461 tgtagattct cctttactta atcaagtaag catactttac agccaatgcg aaaaaaagtc
    17521 tattgttctg cttgcgtttc tcgaatagct ttattatact cgaaaaatcc gctgaaaaac
    17581 aatagacttt tataaatcat tgatcaatca ttcgaaagat tttctccatt tgaatcaatt
    17641 acttttttat accagttgaa tgatttcttc ttcgaacggg ctaatgtgcc atttccttcg
    17701 ttgtcacgat cgacataaat gaatccgtac cttttcttca tctcacctgt accagctgat
    17761 actaaatcaa tacatcccca agtcgtatag cctaatagat cgactccatc taattctact
    17821 gcatctttca ttgcctggat atgtgctgcc agatagtcga ttcgatagtc atcttccaca
    17881 taaccattct catcgggcgt atcgactgca cctaagccgt tttctacaat aaatagtggt
    17941 ttttgataac gatcataaat atcattcatc gttattctca agcctaatgg atcaatttgc
    18001 caaccccatt cacttgcttc cagatatgga tttttgacag aagcaaagat atttcctgca
    18061 gtctgttcca agagttcgtt gtcagtagtc gaaactcgag aagaataata agaaaaggag
    18121 ataaaatcaa cagtatgttc tttcagcaat gcggcatccc caggttccat tttgatctga
    18181 atgccatttc gttccatttc tttcaatgca taagcaggat attctcctcg tgactggaca
    18241 tcaatgaaga aataattttc tcgatctgat tttctagaag cccaaacatc ttcaggattg
    18301 caagtgtatg gataatatgc tcctgctgcc agcatacagc ctactttgtt ctccggatct
    18361 acttcatgag caatcttcgt tgcgatggca cttgcaacca actcatgatg tgccgcttga
    18421 tatttgattt gttcttcatt ttctccttct tcaaaataca gccctgcgcc catgaatggt
    18481 gcatgaagga tcatattgat ctcattgaat gtcaaccaat atttgacaag tcctttatag
    18541 cgattgaaga tgactcggca cagattttca taaaaaccaa cgagttctct ggaacgccac
    18601 gcaccatatt ctttgatcaa atgcatcgga caatcaaaat gtgtaatcgt cacaagcggc
    18661 tcgatcccgt acttttgaca ttctttaaag acatcctcat aaaatttcaa accagattca
    18721 tttggctctt tttcatcgcc cattggaaaa atacgactcc aagcaatgga catccgataa
    18781 gtcttgaacc ccatttctgc aaataaagca atatcttcct tataatgatg atacatatcg
    18841 atcgcaattt ttgctggata aaaatgattt tcatcaaatt caaacatttt cttttttcca
    18901 gtaatgacag gaaaacggtc ttctccgatt ggcacaacat ctacgttcgc taacccacgt
    18961 ccgccttcat cataaccgcc ctcgcattga ttggctgctg tagctccgcc ccataaaaaa
    19021 tcttttctga atcccatcat acttcctcca ttacatgtgt attgcttgat aattctcttg
    19081 ccagttcatc ttggacttcg attccttctg cttttaaccg gctgattgtt tccttgaatt
    19141 gcggtaaata ctgctgatgt gcaataaaca actcattcat gatccgtttt gctgtctttc
    19201 ctgatcgtat aagcggattg atcgtaaacg cttgtaaagc tgttccataa tcaccagtca
    19261 cagctgcttc gatcgtcagc aattccatat tcttcattac ttgcaaccag cctctttcag
    19321 cagcaggaag ggaaccaaac gctacatttc gtgcgccttg tgcgccaaca taggcagtga
    19381 cttctactac acaatctgcc ggcagatcag gaacagctcc atcattcttt gtagatacca
    19441 cgatctgtgt ttctttattt ccatagatcg aagcaatcgt ttcacaggca gcatctgaat
    19501 aataagcacc acctcgtttt tgcaattgtt caggtttatg atccaattct ggatctttgt
    19561 ataattcaaa cagctctgct tctgtttctt tcacttgctg cgctcttgta ccaatcgttt
    19621 gatattcttc taaagcatgt tccagcattt cttcttcacg gtagtaatag cggtggtagc
    19681 cacaagggat catgttcatt tgttttaatt gttctttgaa aaacgggata tcaaagatat
    19741 ttttcggcaa tccattgtct tcatcgtata aacgatcaat caattctgcc gtgcggtcat
    19801 ttcctttatt atctgctact ttgtgccaat ggaagtgatt tagaccggca aacttgtaga
    19861 tcagctcttc ttttttcttg ccaagcattg ttggttctgt catcatcgcc attactggca
    19921 cattgcataa tcctatcact ttatcccatt tgccatatct gataactgct tctgtcacca
    19981 tcccgcttgg gttcgcgaaa ttgatcagcc aagcatttgg acataaacgc ttcatgtctt
    20041 caacgattgc caaaaccact ggaacggtac gaaaagcttt gaatatcccg ccagcaccat
    20101 ttgtttcttg cccaatcatc ccataataac tagggatccg ctcgtctttg attcgtgcat
    20161 ctaattgacc gacacgaaac tgagtcgtaa caaaatccgc atctttcaat gcttcttccc
    20221 gatccagagt tgcatagatt ttgacttcat acggagaagc atcccacata cgctgagaca
    20281 tctgactgac gatctcaagc ttttcttttc cttcttctac atctacgagc cagatttctc
    20341 gtatcggtaa ttcctcatat cttttgataa atccttccat caactcgggg gtgtaactgc
    20401 tgcctccacc aatcgtagcg attttgattc cttttgccat gttctcactc ctttactttt
    20461 tacactttta ttatcttttt tgtaaacaaa acaaacaata gaaattcgtt tctttccagt
    20521 aacatttaca aaagttagtg ttttctactg gatttttgta aatatcttgt caaaaaatgt
    20581 ctttattaag ctatataaca taaatccgtt tacaaatcat tttcaaaaaa gttataattt
    20641 acgtaaaaaa acaagaagaa ggtatctaca tgttattacg tgaaaaaatc aaagaaatct
    20701 ccttttctcc ttcagaaaat gaagtgattc agtttctctt aagcgattct ccagcacttg
    20761 gcgaaatgac catccaagag attgctgagc gatgttatgt ccacccgtcc acactcatcc
    20821 gtgtagcaaa aaaaatgggt tttgatggct gggtcagttt tcgtaatgct tttttagctg
    20881 aaacagccta tcttgaaggg aattttcaag acgtagatgc gaatcttcct ttttccacca
    20941 cagacggtat tatgacgatc gcaaataaaa tggcttcttt agaacagatg acgattcaag
    21001 atacactttc tctcattcat catgaccaac tgcaaaaagc caaacaacta atgcttcaag
    21061 caaaaaaaat cgtgattttc gccagtaact cgaatacttt gatttctcaa gatttcatgc
    21121 tgaaaatgaa gcgcatcaaa atggatgtca cgattgtcac cacttttggt gaatcgttct
    21181 atgaagcgta caattgcacg agtgatatgt gcgggattct gatttcttat acgggtgaaa
    21241 acaatgtgat ccttcgtacc gcagaaatat tgaaacaaaa tcatgttcca attttagctt
    21301 tgaccagtat cggtgattca acgctatctt caatgagtac agccgctttg cgacttacga
    21361 cacgcgaacg actgtattcg aaaattggta attttacgat caatacatcg atttgttatc
    21421 ttctagacgt gttatatagt tgtgtttttg cagaaaatta tcaacagaat ttagtccatc
    21481 taatttctgt aggacaaaaa tttgataaac gccctatcag ctcagccatc atgaaagagc
    21541 ctttcaattt tgaaaataaa gaagtggact aaaaagaata attaagccta gtccattctt
    21601 tcacctaacc gttcaggtca gtgcggtgat aagtgcatcg tctggcccga ccgtctcccc
    21661 ttgattttcc aaaatatcca aataatccgt gtaattggtg acgatcacag gtgtttctaa
    21721 actgtatcct tcctcttcga ttttcttttt gtcgaagcgg agcaacagat cgccttgttt
    21781 cactctttct ccttgctgca ccaagctttc aaaatatttc ccttccaact gaacagtatc
    21841 caatccgaca tgaatcagca attccagacc tgcttcagaa accattccga ttgcatgttt
    21901 cgtcgggaac agggtcatga ctgttccgtc aaaaggggca cgtacttctc ctttttcagg
    21961 gtagatcaag attcctcgac ctagtgttcc ttgtgcaaaa gctgcatcct ttgctgcatt
    22021 cagtggagcg atttgtcctt gtatcggtgt ttttacaatt tctttacctg atcttttctg
    22081 tctatcatct gtttcacctg cttcctcctt ccaaaagaaa aaagtcagcg caaaggatac
    22141 caccatcgca atggcgattc caatcaatac attaatcaca tccgttaaat caccatctgg
    22201 tctaatatag ttgggaattg taaagatgcc taatccacct ggattccaag aagttaaatt
    22261 cattaatcca ctatacgcgc cccctaacgc accaccgaca caggtaaaaa taaatatttt
    22321 tttacgtggc aatgtaaacc cataaatagc tggctctgta atccccacaa taccagaaac
    22381 aatggctggt attgcgattg ctttgtcttt tgggtttcta agcttaaagt agagtgcagt
    22441 aagtgctgca gtttgtccaa aagacactac tgcaacaggt gtcatgatat tttgccaacc
    22501 attcacagaa aattgcatca atcccattgg tacgattgcc caatggagac caaacatcac
    22561 tagaatttgc cagaagaagc ctacgattgc tccataaata actggcgaaa gtgctaaaag
    22621 tgtttcaaat ccagccatta aaatatcagt tgcgaatgtg aatgctggtc caacgagtaa
    22681 aaaacctaag ggcattgtaa taagaacggt gaagaatgga acgaagaaat tcgcgatcat
    22741 ctcaggtact aactttttaa ttggtttctg aatttggcta gctaacaaca caataaagat
    22801 aatgggaatg acagaagaag cgtagttacg cgcaatccag ggaatgccga atactgtttg
    22861 ataaataggt gcttcaaaaa tagtgccaga aaatatggta gtcagtggtg cttctgctgc
    22921 accactcaaa gcttccagcg acaagctagg attcattaat gctgccccaa gcaacatccc
    22981 tacgaattca tttactttaa atttacgggc agctgttaaa ccgataataa caggcataaa
    23041 ttggaataca gaatcaccga tattatcaaa cataacaaat gtgccagaac cgcggtcaaa
    23101 tgcgcctaag aagacaagta atgctgtcag tccacgaatc atcccaccag cagctagaat
    23161 agcaaggaat ggctggaaac agcccgatat tccatcaata agcatatcaa acggtctcat
    23221 tttttctgtt gaaacagcct catcaaaagt aaggtttcct gcttttataa cctcttcaaa
    23281 cacgactggc acatgattcc cgatgacaac ttggtactgt cctcccgctc gcattaccgt
    23341 cacaacaccg tccatatttt tcaagatctc atcatttgct ttttcttcgt tttttaattt
    23401 gaaacgaagc cttgtgatac aatgtgtcaa accattgata ttttccttcc cgccgacatt
    23461 ttctacaatt ttgctcgcta attcttgata ttttcccatt tctattccct ccaatttatt
    23521 agtggaaggt ttagccaact gaatgtcact acccttattt catgcgttct tgttaattta
    23581 tcctcctttt tttatttatt tacaacgatt ctcatgcact aaacgcgcaa tatggatcgt
    23641 taaatacatt ttttcgtccg tggacatctg gtagttgaat atctcggcta aaaagtctgc
    23701 tattttctca acgcaaccaa acgtatcctt atattttttt tgaataacct ggtacaattc
    23761 ctcagaaact tctcccactt ctgatttttc tccatctagg acgcgtgtca gaaaaaaacg
    23821 taggtgtgtg acgaatcgaa aaaaatggac tgaatcttca tcaaatgtaa tcttatagta
    23881 atagcggacg atatttagaa tatcctgtat tgttgtagta aacaggtagg tattgtcttg
    23941 ttggctttga atgccttgtg cattgactaa atgcaatgcg ataaatccgg cttcatcttc
    24001 tgataacttg atgtggtatt tatccgagat tttcttcact gtttttttcc cgatggcata
    24061 ctctttagga aatagttgtt tgatatcata cagcaataca tttggtacaa atattcccat
    24121 tttgtgacgt tcgatagccg tatacaaatg atccgtcaat gcaatataca ccgaatcatt
    24181 caactggact tgtagagcct cttttgtata ttcaatgatt tcacaagaaa tttctaagta
    24241 ctcaagagga atcgcttgtg ccaattcttg gaactgttgt gaaagtccgt catttgtcaa
    24301 ctgaaatttt ttgtcgatgc atgagtcaaa aatcgggtca cccactttct ttttgaatgc
    24361 caaacctttt cccatcacga tcatttcctg atttctttca tccctggtta ttacgacgtt
    24421 gttattcagt actttctcaa tcagcatgtt ttactccttt ccatgatata tagggctgta
    24481 tccaaaacaa aaagaaaaac ccaaaaagcc gtccatggaa ccatgggaga ctcatcaggt
    24541 ttagcttgca tcaggcaatc actatccaag ttgtatcgtt ttctttatat tatcgaaagc
    24601 aagcactttt gtcaacgctt tcttagcggc tattgggcac ttctgactag ctgtcgtgat
    24661 tttttttaaa tctggtaatt acgacactaa cgctcacaga tgaagaatct gggaagctct
    24721 gttttatttt cactctagcg cttaggtcaa aatgctacta tgctactgtc ccaacttcta
    24781 atatacggtg ttccagtacc agcttatcgg tgataagcca aatttatgca aaaatctgga
    24841 aagccttttt tacaattttt ttcttatcac ctaaagctga acggagccct gtcacaacca
    24901 ctttttacac accactgctt tgcagtttgt acatatctgc atacaaacca ttttgcgcta
    24961 gaagtgtttc atgattccca cgttctacta tatgaccttt gtctaaaact aaaatcaatt
    25021 ctgcatcccg aatcgtggac agccgatggg caatcgcaat cgttgtccgt ccttgtcgca
    25081 tttttgtcaa tccttcttgg atcaatcctt ctgtttcagt atcgatattt gctgtcgctt
    25141 catccaatac tagtatttta ggatctgtca cgattgttcg cgcaaaagtg atcagctgtc
    25201 gttgtccgct agaatagctg gcaccgtgtt cgatcacttt tgagtgatat ccttttggta
    25261 attcatcgat gaacttgttt gcttgaacaa actcagctgc atggcgaatc tgttcgtctg
    25321 tgatagttgg attcatcatc cggatatttc ctgcgatatc tccataaaac aagaaggcat
    25381 cttgcaagac caatcccatt ttcttacgta actcttccat tggatattct cgaatgtcat
    25441 gatcatcaat caagatctgg ccttcataaa attcgtaaaa ccgcatcaat acgttgatga
    25501 tcgagctttt tccgcttccg gtgtgcccca ctaatgcaac ggtctctccc ggattagcga
    25561 caaaagagat attgttcaat acattgtgct ctccatcata agaaaagctt acattgcgaa
    25621 actcgatctt acctgaagta atcgcttgat ctgctccagg attttgttgc ggtgcatatt
    25681 cttctgtatc catgattttc aaaatacgac taccggcaac cattccatct gtaaaggtgc
    25741 tcaaaaagtc catcatttga gacattggat taaaaaatcc ctggacatag gtcgtaaatg
    25801 catagatcag tccaacttct acgggagaat gcagcgcatc gatcccaaac aaagtcaacg
    25861 ccaacgcaat cgccaatgca tatagaaaat tgatgatcgg acttaacaga atcgaatttg
    25921 ttttgatcat cgcatagcgc gtgtctaaat actcgttgtt cacttgttca aattctttag
    25981 ctaaacgagc ttcttggcga aactgctgga taatacgcat gccggaaatc gattcattca
    26041 atttcgtgtt cagctgactt aatttttccc gcatattccg gtaaatacga gaactgaatt
    26101 tctggtaata ccagatgacg attcctaaaa tcggcaagaa caccaaagtc cacaaggcaa
    26161 tttctccatt gatttgaaac atggcaatga aggaagaaac gactgcaaag atcccagtca
    26221 ataccatcaa aaagacatac caaaattcaa atagcgtttc tgtgtcattt gtcactcgag
    26281 aaacagtcga tcctgccggt gtctgatcaa aataacgcat acctagtgta tgcagctttt
    26341 caaataatct tacccgaaca tactgatagg tcttcaatga agccatggaa tacaaatacc
    26401 attggaaaaa ccaaatgata cttttgacta tgactccaaa caagtacata ccagcaaaaa
    26461 acaaaataac ttgtgtcgta gccgactgtt tagccagatg atcatccata aaagtttgga
    26521 tgatccttgg caataggaca ttgatcacag acagggcaaa cgcaaataag atagcaacga
    26581 tgaacgttct tctaaaaggt ttggcgaact tcatcagtcg tttgatgatc ttcttctgtt
    26641 ctttaagtgg aatcgatttt gtccattccg attgataatt ttcatccatc aggcctcgcc
    26701 tccttctatc ttcgcttcta atttctgttt ctcccacatt cgttcatacc agccgcctaa
    26761 tgcaagcagc tcatgatggg ttcctcgttc aatgattttc ccttgatcga caacaatgat
    26821 ttcttttgca tgcatcacgc tgcttaaacg gtgagctgca atgatggttg ttttctcttt
    26881 tcttatttct tttaaattat gcaagatagc ttcttctgtt ttggcatcta ctgcagaaag
    26941 tgcatcatct aagatcagca attcaggatt tttgatcaat gctcgagcaa tcgaaatcct
    27001 ttgtttctgt ccgccagata aagagactcc acgttctcca actaaggtat cataaccttt
    27061 tggtaattcc ttgatttcat tgttgataaa tgctaaagaa gccgcatgct ctacttcttc
    27121 ttctgaaagt tttggattag aaaaacggat attatctcga atggtcatcg aaaacaagaa
    27181 gtgatcttga ggcacatagc cgattgatcc taataaagca ttcaatgaat attctttgat
    27241 cgaacatccg ccaaattgaa tttttccttg ataatcatcg tattcacgca tcagtaattt
    27301 gatgattgtc gtttttcccg caccagtttt cccaacaata cctaatgttt ctccttcttg
    27361 gatcgcaaat ttgatttgtt ctaatgctgg tgattcttct ttcggatagt taaaagagga
    27421 aatagctaca ttcagctcgc cttttgccgg agtctgcact gcacccagtt gttccacgat
    27481 atgcgtcttt tcatgcaaaa gttcattgac gcgatcataa gaagcatttc ctctttccaa
    27541 tacgttgaac aatcgaccaa tcgcaaacat cggccaaaca agcataccga tatagctaat
    27601 aaatgagacc atctgcccga ttgagatcgt gccttccaag acatactttc cacctaaaat
    27661 aattgttgca acataagaca gaccgataat caaggtaatg aatggatcaa ataaggagtc
    27721 taaaaaattg actcgtttgt ttttaataat tgcatcttca atcttttctt caaaatccgc
    27781 gagatcttct ttttcttgtc caaatgtttt aatgactttg atcccagtaa tactttcttg
    27841 tgtcttatca ttgatactag aaaaagcttc ttgcgaatca cgaaaagcat cgtggagttt
    27901 tgaccccagc actcgtgaag taacggctag taaaggcaga ggaatcagcg caatcagtgt
    27961 taagcgccaa tcaataaaca aaatcatcgc aatgatcgtt gttccgcccg tgatcactga
    28021 atctgcaaag gtcaagatac cagctcctgc tacattttgg attgcattca aatcattcgt
    28081 tgcatgagcc atcaaatctc cagtccgata tttttggtaa aagagattgt ccatttctgt
    28141 aaaatgtttg aatagctgct gccgaagttc tttctccaac cgagctgcac ttccccaaat
    28201 attcgtccgc cagatataac gaaaaagata ttgtaagaga gctgcaagga tcaataataa
    28261 gatccaccag gaaatgatct ttattgataa atttttatcg gcgatctcat caatgatgat
    28321 cccaatcact tttggaggag ctaactgtac caaggccact gcgaataggg agaaaatccc
    28381 aattaaataa tgtttctttt cctgtcgaaa aaaccaacct aattttctaa aaatcgacat
    28441 tttactcctc ctttgtcttt atcaagagca taggattgtc tgtgcttgtc ttttttgctg
    28501 aatagtctga atagtctaac aaattacgaa ataaaaaacg gactgaaaaa atcagcccgc
    28561 aaaaagtctt tgggtcagaa cctatttttt cccttggttc ttcatttgct gcatcatctg
    28621 gcgaattttc ttctcagatg gtttttgccc cattgacatc atcattgatc gcaacatgtc
    28681 ctcattaacg ggaggatttt tttctaaata gtctttcata tatttacgcg ctaggaaaaa
    28741 gccacctact gcgccgatta gcaaagcaat aatagcaata agtacgacaa tacctgttga
    28801 taccatataa atctctcctt tctatttccg aattgctctc aatgatttat tttactaaag
    28861 tttattgaaa aaagaaaggc gtattcttta gtttcatgca aaaaatagtg gtttttttag
    28921 agaagaacaa aatttctttc attaaccagc aagacacgcc acgaaaaaaa attaggcata
    28981 ccaaatcttt ttctttaatt ttttctttct gaggtgtaga atgtaatcgt agataaatag
    29041 gaaaggtggt tttttcttga ataatcaatc caacaaacaa tttcataagc atcgacttat
    29101 tgaacataca aatggtttat ctttagctga agtaaatgga acagtggatg tacccaaggg
    29161 aaaaagtttt tttaaaacac ttcttgctta ctctggacca ggtgcattag tagcagttgg
    29221 ttatatggat ccaggtaact ggtccacttc gatcactggt ggacaaaatt tccaatattt
    29281 attgatgtca gttattttga tgtctagtct gattgctatg cttttacaat atatggcagc
    29341 aaaattagga atcgtgaccc aaatggattt ggcccaagca atccgagcac ggacaagtaa
    29401 gacattgggt gtcattttat ggatcttgac tgaattagcc attatggcaa cagacatcgc
    29461 agaagtcatt ggtgcagcaa tcgccctcta cctgcttttt gatattccat tggtaattgc
    29521 cgtatttatc actgtgttag atgttttcgt ccttttattg ctgacaaaag tcgggtttcg
    29581 taaaatcgaa gctttggttg tctgcttgat tttcgtcatt ttattcgttt tcgtctatca
    29641 agttggcttg tctaaccctg attggcacag tttgtttgcc ggatttatcc ctaacagtca
    29701 cacattctca gactcaccgg tcatcggcgg cgaaactccg ctgactggag ctttagggat
    29761 tattggtgca acagtcatgc cgcataactt atatcttcat tcagcagttt ctcaaactcg
    29821 gaagatcgat caccaagacg aagaagatgt agcacaagcg gtacgctttt ctacttggga
    29881 ttctaatatc cagttgtcaa tggcttttct agtcaatgca ctgctattga tcatgggtgt
    29941 ggctgtattc aaaaccggtt ctgtccaaga tccttccttt tttggtctgt atgaagcttt
    30001 atctgatcca tcagctatga gcaatggtat cttgattgct gtagcaaaat ctggtatctt
    30061 gtctacttta tttgctgtag cacttcttgc ttctggccag aactctacta ttactggtac
    30121 gttgaccggt caagtcatca tggaaggctt catccatatg cgtatcccaa tttggctaag
    30181 aagactagtc acacgattgc tttctgtgat tcctgtattg atttgtgttt tgtttacaag
    30241 tacaaaagga acgatcgaag aacataccgc tttgaataac ttgatgaatg aatcccaagt
    30301 ttttctggct tttgcattgc cattctcgat gattccttta ctgatgatga ccaatagcca
    30361 agcggagatg gggagccgat tcaaaaattc atttgttgta aaactacttg gctggttctc
    30421 tgtgattagt ctgacttact tgaatttacg aggattacca ggtcaaatcg aaagtttctt
    30481 cggcgagcaa gccacctcag ctcaactagc attggctgat caaatcgctt atgtaatcat
    30541 tgttcttgtc cttctcctgt tggcatggac gattggtgat ttatataaag gaaacaaaaa
    30601 atatgaacag cgtttgcagg aaacgataga agaaatcgag tagaaactga ttcttttaca
    30661 caaaggaggt tgtgtcagaa gtgggcagct tcaagaaata agaaggaatt taagaaaatt
    30721 gcttttcaaa tttttgtgaa atttcggctt atttccgaag aagttacttc tggaacaccg
    30781 tgtatcagag gttgtgaaaa agctgccttg catcaagtaa taagaacagc caagtaaaaa
    30841 cagcttttta tgtttttaac ttggttggac ttattaccgc agatgcaagc ttttgagcac
    30901 cgtttattcg gaaaaaggaa ctgcgacaag acttttgtca cagttccctt tcctacgatt
    30961 agtcaagtaa aaggtgtaag aaaaatagct cataaacgaa agcgacaaaa tcaa
//
LOCUS       DADQDV010000030        29099 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.030, whole genome shotgun sequence.
ACCESSION   DADQDV010000030 DADQDV010000000
VERSION     DADQDV010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 29099)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29099)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29099
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.030"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..1031)
                     /locus_tag="J8S10_001439"
     CDS             complement(<1..1031)
                     /locus_tag="J8S10_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAZ9630027.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMVALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTV"
     gene            complement(1113..1802)
                     /locus_tag="J8S10_001440"
     CDS             complement(1113..1802)
                     /locus_tag="J8S10_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAZ9630028.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(1908..2276)
                     /gene="rplL"
                     /locus_tag="J8S10_001441"
     CDS             complement(1908..2276)
                     /gene="rplL"
                     /locus_tag="J8S10_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HAZ9630029.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(2329..2832)
                     /locus_tag="J8S10_001442"
     CDS             complement(2329..2832)
                     /locus_tag="J8S10_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HAZ9630030.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     gene            complement(3242..3931)
                     /gene="rplA"
                     /locus_tag="J8S10_001443"
     CDS             complement(3242..3931)
                     /gene="rplA"
                     /locus_tag="J8S10_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HAZ9630031.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(4035..4457)
                     /gene="rplK"
                     /locus_tag="J8S10_001444"
     CDS             complement(4035..4457)
                     /gene="rplK"
                     /locus_tag="J8S10_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HAZ9630032.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            4800..5468
                     /gene="sdaAB"
                     /locus_tag="J8S10_001445"
     CDS             4800..5468
                     /gene="sdaAB"
                     /locus_tag="J8S10_001445"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit beta"
                     /protein_id="HAZ9630033.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            5481..6353
                     /gene="sdaAA"
                     /locus_tag="J8S10_001446"
     CDS             5481..6353
                     /gene="sdaAA"
                     /locus_tag="J8S10_001446"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HAZ9630034.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(6444..7463)
                     /locus_tag="J8S10_001447"
     CDS             complement(6444..7463)
                     /locus_tag="J8S10_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HAZ9630035.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(7636..8523)
                     /locus_tag="J8S10_001448"
     CDS             complement(7636..8523)
                     /locus_tag="J8S10_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAZ9630036.1"
                     /translation="MTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEVSDKEKT
                     AESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDGQIQATG
                     DLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSMGGVSAL
                     RYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQDYQQMI
                     GNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTGENASHS
                     MLHENQEVDQLVSRFIWKE"
     gene            complement(8600..9145)
                     /gene="nusG"
                     /locus_tag="J8S10_001449"
     CDS             complement(8600..9145)
                     /gene="nusG"
                     /locus_tag="J8S10_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HAZ9630037.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(9246..9416)
                     /gene="secE"
                     /locus_tag="J8S10_001450"
     CDS             complement(9246..9416)
                     /gene="secE"
                     /locus_tag="J8S10_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HAZ9630038.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(9440..9592)
                     /gene="rpmG"
                     /locus_tag="J8S10_001451"
     CDS             complement(9440..9592)
                     /gene="rpmG"
                     /locus_tag="J8S10_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HAZ9630039.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            9754..10398
                     /locus_tag="J8S10_001452"
     CDS             9754..10398
                     /locus_tag="J8S10_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAZ9630040.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(10454..10957)
                     /locus_tag="J8S10_001453"
     CDS             complement(10454..10957)
                     /locus_tag="J8S10_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HAZ9630041.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(10970..11016)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            11554..12519
                     /locus_tag="J8S10_001454"
     CDS             11554..12519
                     /locus_tag="J8S10_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HAZ9630042.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(12618..13790)
                     /locus_tag="J8S10_001455"
     CDS             complement(12618..13790)
                     /locus_tag="J8S10_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9630043.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(13777..14922)
                     /locus_tag="J8S10_001456"
     CDS             complement(13777..14922)
                     /locus_tag="J8S10_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9630044.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(14936..15868)
                     /locus_tag="J8S10_001457"
     CDS             complement(14936..15868)
                     /locus_tag="J8S10_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9630045.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            15985..17064
                     /locus_tag="J8S10_001458"
     CDS             15985..17064
                     /locus_tag="J8S10_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAZ9630046.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            17061..17679
                     /locus_tag="J8S10_001459"
                     /pseudo
     CDS             17061..17679
                     /locus_tag="J8S10_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
     gene            complement(17789..18016)
                     /locus_tag="J8S10_001460"
     CDS             complement(17789..18016)
                     /locus_tag="J8S10_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005229738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAZ9630047.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(18119..20707)
                     /locus_tag="J8S10_001461"
     CDS             complement(18119..20707)
                     /locus_tag="J8S10_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HAZ9630048.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(20727..21386)
                     /locus_tag="J8S10_001462"
     CDS             complement(20727..21386)
                     /locus_tag="J8S10_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAZ9630049.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(21435..21938)
                     /gene="trmL"
                     /locus_tag="J8S10_001463"
     CDS             complement(21435..21938)
                     /gene="trmL"
                     /locus_tag="J8S10_001463"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HAZ9630050.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(22159..23025)
                     /locus_tag="J8S10_001464"
     CDS             complement(22159..23025)
                     /locus_tag="J8S10_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAZ9630051.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            23134..23775
                     /locus_tag="J8S10_001465"
     CDS             23134..23775
                     /locus_tag="J8S10_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HAZ9630052.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(23837..25198)
                     /gene="mgtE"
                     /locus_tag="J8S10_001466"
     CDS             complement(23837..25198)
                     /gene="mgtE"
                     /locus_tag="J8S10_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HAZ9630053.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(25216..26115)
                     /locus_tag="J8S10_001467"
     CDS             complement(25216..26115)
                     /locus_tag="J8S10_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAZ9630054.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(26117..26914)
                     /locus_tag="J8S10_001468"
     CDS             complement(26117..26914)
                     /locus_tag="J8S10_001468"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HAZ9630055.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(26892..27596)
                     /locus_tag="J8S10_001469"
     CDS             complement(26892..27596)
                     /locus_tag="J8S10_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HAZ9630056.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            27727..28302
                     /locus_tag="J8S10_001470"
     CDS             27727..28302
                     /locus_tag="J8S10_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HAZ9630057.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            28420..29097
                     /locus_tag="J8S10_001471"
     CDS             28420..29097
                     /locus_tag="J8S10_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HAZ9630058.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
BASE COUNT         8562 a         6167 c         5232 g         9138 t
ORIGIN      
        1 aatacagtat tatttcggtt gcttgctgct tcacctagcc cttgtactcg tgtttgattg
       61 gcgacttgac caaattgatt cccgacgtct aataaaataa tagctaaaag caaaatggcc
      121 aaatggcttc cgccaaccaa taaagcaata aagcttattg tttgcataac aagtcccata
      181 tacacgattt ttctttcaga ataagaatct gccagtcgtc ccacgatagg tgcagcaact
      241 gctccagaca aaccaaaaat cgctaatatc cctgcttcga atgttcccca attgtaggcg
      301 ggactgctga tataaaaaat caacgtagac caaaagatcg aaaatgttcc aaacatgaaa
      361 aatccactga ctgccgcttc tcttaataga cgttgagaag caactaaatg cggcaaactt
      421 ttaagtgaat caaggtatga aacagctgta ctactttgct ggacagaacg cggcattttc
      481 cagtaaagca gaagtgtaag aattccgact gcacataaag caaataaata gatcatccgc
      541 caagaaaaaa gactggcaac aataccagat accgtccgag aaagcaaaat ccccacgagt
      601 aaaccgctaa gcaatgtacc catgaccttc cctcttgctt ttggtcccgc tagtaccgca
      661 ccgtaaggaa tgatgatttg cggcacgatc gaaagtaatc ctattaaaaa agaagcgcat
      721 gcaaataacg taaacgaagg cgcaaaaaaa gcggccaaca gagagacggc agataacgct
      781 accattcgaa tgatcaattt tggacgatcc accacgtccc ctaaaggaac taaaaacagt
      841 aaccctaacg catagcctaa ttgggtcaac atcgtcaata tcccgactgc acttgtgcta
      901 acagataaac tagctgctac ttttgttcca atcggctgga tgtaatacat attggcaaca
      961 acaacgccac aagtgattga taatagtaaa ataagcgaag ttgttaaagg tgttttttca
     1021 ttactcttca ttgatttccc ccatttccta tcttagttta caacttatgg aaaagattgg
     1081 aaatagaaaa atacaactat tcgccacact tattatttgt gcttttgttt tccttgtttt
     1141 ttcttgcgat ctttataaat gaagacaact aaccctacta gcacagtaac acttgcaacc
     1201 aacgtgactg cagttttgtt atatccgtga aacagagctt ctccaccaca cgcatacaac
     1261 acagacgaag ggatgactcc aatcacgatc gacaatatga tttgctgtag aggcaatttc
     1321 atcgcatctg cagcaaaatt gaccatagaa gatggaataa ccggtatcat atagcctaac
     1381 attacaccta tttttggatg tttcatttgt cggattgctt gcacccaatg attcgtttcg
     1441 gttttcttat ctaaaaattt taagcgatgc ataaggaaaa ttgcagtgat gttaccaaga
     1501 gcattaccca aaatgttgat gatcgcacct gtcagtggtc caaagctcaa accagcaatg
     1561 actccaacta ctgaagtagg aatacctgga acagcacaca tcaccgctgt caatacgatc
     1621 aagagtatcg atgcaaaagt cccatgcgaa cgaatatgtg cgagtagctc tgccttactc
     1681 gctctcggat ttaaaaataa ttggatgtct gtctgatatt ctaaatacaa ccgatagccc
     1741 actaccagta tcagaatgat tcccaacgag atcaacatca atcggattat tttctttttc
     1801 atatttcctc ctgaaaaaaa tctatattca ttaaataata gtttaacata aaaacaaaaa
     1861 agcaccgaaa tccaacatag gatctcagtg cttttaaata gtaaaaatta tttaacagtt
     1921 acagatgcgc caacttcttc aagtttagct ttcaattctt cagcttcttc tttagatacg
     1981 ccttctttaa ctggtgcagg agcgccatca actacagctt tagcttcttt caagcctaaa
     2041 ccagttgctt cacgaactgc tttgataact ttaacttttt ggtctccagc tgcagttaat
     2101 tctacagtga attctgtttg ttcttcagca gcagcagcgc caccagcagc agctacagct
     2161 acaggagcag cagcagatac gccaaattct tcttcaatag ctttaactag gtcgttaagt
     2221 tctaggatag ttgcttcttt taactcagca acgatgtttt caatgttcaa tgccattata
     2281 atttcctccg tttaattgtt cttttttatt taatgcttta tgcggcaatt aagctgcatc
     2341 tccatcttct ttgtctgcca ctgctttgac agcgtaagcc acgttgcgga ctggcgcttg
     2401 tagtacagat agcaacatag atagaagtcc ttcgcgattt ggcaattttg ccaatgctgt
     2461 gatttcttcc aatgaagaga ctttaccttc gatgataccg cctttgattt ctaatgcttt
     2521 tgcttcttta gcaaattcgt ccatgatttt cgctggtgcg actacatctt cgttactgaa
     2581 tgcaacagct gtaggtccag tgaatacttc gtccatgcct tcaaggccag cttttttagc
     2641 tgcacgtgaa agaatagaat ttttgataac tttcatttct acgttagcat cacgaagttg
     2701 tttacgtaaa cgtgttactt catcaactgt taatccgcgg tagtcaacga ctactactga
     2761 tgcagctgct gtaaattttt cgcttacttc atcaacgatt gctgcttttt ttgcgataat
     2821 tgcttcactc atttttgagt ttcacctcct gaattttgat ggaagagttt tttgcactga
     2881 aaaggcaagt cacttttata gttactttgc tcaaccagta ttattcatca cctattcact
     2941 tcgttcatag tgattctact cgctttgctc gaaaggaaac tcctttcgct ttgctcaacc
     3001 agtattgttc atcatctctt cacttcgttc atagtgattc acaataaaaa actctatgcc
     3061 accgcagaca tagagggact attgaatata ttcaataaac gtcctcggta ggaaattaag
     3121 gcttgatgcc acctactgtc ttcggtacaa gttaattatt aacctcaact agcttagcat
     3181 gctaaactag ttgagtcaag aattattttt cagttggatc aatcaacatt ctaatattta
     3241 attagaaaga agcttggtca acatggatac caggtccaaa tgttgttgtg atcgttacat
     3301 ttttcatgta ttgaccttta gctgctgatg gtttagcttt tagcaataca tcatggattg
     3361 ctgcaaagtt ttcaactaat ttttcatcgt caaatgaaac ttttccgatt ggtacatgga
     3421 tatttccagc tttgtccaca cggtaagtta ctttaccagc tttcacttcg tttactgctt
     3481 ttgttacgtc cattgtaact gtaccagttt tagggtttgg cattaagcct tttggtccta
     3541 atactcgtcc tagacgacct acagtagcca tcatatcagg tgttgcaaca actacatcaa
     3601 agtcaaacca tccgttttgg attttttgaa ccatgtcgtc gtcacctacg aaatctgcac
     3661 cagctgcttc agcttctttt gctttgtctc ctttagcaaa aactaaaaca gtttgtgttt
     3721 taccagttcc gtttggtaat acaacagcac cacggatttg ttggtctgct tttttagggt
     3781 ctacgttcaa acggtatgca acttcaactg ttgcatcaaa ttttgcaatg tttgtttctt
     3841 ttgctaaagc tactgcttcg gcaacaggat aaactttact tgaatcaact ttttttaatg
     3901 catcttgcat ttttttgctc tttttagcca ttttggttcc tccttgattg tggttataac
     3961 ggttgtacct cccacgtgtt ctatatcttt caatatagag ccaactgaga agctgctgtc
     4021 ttagggtgta tagattattc tacagtgatc cccatgcttc gtgcagttcc ttcaaccatg
     4081 cgcattgctg cttcaacgtt agctgcgttt aggtcttcca tttttaattc agcgatttct
     4141 cttacttgat cgctagaaac tttcgcaact ttatttttgt ttggttcgcc tgaacctttt
     4201 tcgattttag ctgctttttt caatagaaca gcagctggcg gtgtttttgt aacgaatgtg
     4261 aatgaacggt cttcgtatac agaaataaca accggaatga tcaaacctgc ttgatcagct
     4321 gtacgagcgt tgaattcttt tgtgaatccc atgatattga tacccgcttg acctagtgca
     4381 ggacctactg gtggagctgg agttgcttta cctgcaggaa tttgcaattt aacgattttt
     4441 tctactttct ttgccacgag acatacctcc ttaagtccgt gatgtggtta attggagatg
     4501 catatttctc ctcccacgtt ttatctgatc tgaaaaaatc cagacaaata atgtgcaaaa
     4561 caatgcacac tggtacagta tagcaaattt atttgttttt tcaagatttt tttctgctat
     4621 ttttacattt tgcttgaata aacgctaaat ttattctaaa aaaacaacaa tttttcgttc
     4681 tcatttcttc ttttatgtta cacttgcgct agcatggttc aacagatgaa agcaaacaat
     4741 aacacggttt tttagaccct tgtacaaaga ttcctacata acaaaatgag gtggagaaaa
     4801 tgaaagattt aaggtataga agtgtctttg atattattgg acctgtgatg attggtccaa
     4861 gtagctctca cactgccgga gctgctagaa tcgggaaaat catacgtagt atatttggcg
     4921 aacagcctga ttctgtagat atttatctat atgaatcatt tgcaaaaacc tatcgggggc
     4981 acggaacaga tattgcatta gttggcggcc tgttagggat ggaacccgat gatgaacgtt
     5041 tagctgattc tttgaaattg gcatatgaag ccggtatgga agtcttgttt gttcctaaga
     5101 gtgaaaaagc cgaacatcca aactctgtaa agatgcttct aaaaaaagga acacgaaagc
     5161 tttcagtcac tggcatttcg atcggcggtg gcaatatcca gatttctgaa ttgaatggat
     5221 tcaaaatttc tttaagcatg ggtactccta ccttgatcgt tgtccaccaa gatgttccag
     5281 gtatgattgc taaagtgact agtatacttt ctgagaccaa tacgaatatc ggcactatga
     5341 cagtgacacg ggaatcaaaa ggtgaaaatg ccattatgat aattgaagta gatgatcctc
     5401 aagtagaaga aacggtaaaa agactcaaac agctgccaaa tatcgacagc gtaaattatt
     5461 tcgattaagg agctaaaaaa atgtttttat cgattgaaga attagtagat caagcaaaag
     5521 cttatccaag tgtagcagaa ttgatgattg cagttgaaat ggaaatgagt ggccgttccc
     5581 gtagtcacat catcgagatc atggaaaaaa acctctcagt aatggaacaa tcaatcaacg
     5641 agggaaaaga aggtgttacc tccgtcacag gaattaccgg tggtgatgca aaaaaattag
     5701 atgattattt aaatgaggca gactttttaa gtggagaaac aatcttaaaa gctgtacgca
     5761 atgctgtagc tgttaatgaa gtcaatgcaa aaatggggtt gatttgtgct acaccgactg
     5821 ccggaagcgc gggtgttgtt cctggtgtgc tgatggctgt ccgagatcgg cttgatttga
     5881 cacatgaaca gcaattggaa ttcttattta ccgctggcgc tttcgggtta gtcatcgcaa
     5941 acaacgcttc tatcagtggt gcagaagggg gatgtcaagc agaagttggt tctgcaagtg
     6001 caatggcagc agcagctttg gtttgtgcaa aaaatgggac tcctcatcaa gcagcacaag
     6061 cagtagccat tacattgaaa aatatgatgg gactgatttg cgatcccgtt gcaggcttag
     6121 ttgaagtccc gtgtgtcaaa cgtaatgctt taggctcttc tcaagctttt atctctgctg
     6181 atatggcatt agcgggtatc gaaagtgtca ttccgccgga tgaagtcgtt gctgcaatgt
     6241 accaagtcgg acgtcaaatg ccgtcgattt tcaaagaaac agcagaaggt ggcttagctg
     6301 ttacgccaac tgctaaacga cttgcggaag agattttaaa taagagggcg tgataaagct
     6361 ccttaatttc gagtattaag agattagtta tcttcataac aaaaaacgaa gagaggacta
     6421 attgcccttc tcttcgtttt ttattaatcc atcaatttcg tattttttac ttcatcgatc
     6481 gtttttgttc ctgcaagttg catcgtgatc gacaattctt tgttcaggtg ttcaaaaaca
     6541 gatgttactc cttctgcccc acctagattc aacccataaa tcactggtcg gccaatcgca
     6601 actaagtcag caccacttgc cagagctttg aagacatgct ctcctcgacg gacaccagag
     6661 tcgaaaatca ctggtacacg tttgttgact acttcggcaa tttttggcaa tacttcaaag
     6721 gacgcaggac ctccatctaa ttgacgtcca ccatgattgg atacccagat accatctgcc
     6781 cctgcagaga tagcgattac tgcatcttct ggcgattgta ttccttttac gataactgga
     6841 agatgggtga tttctttgat tgttttgatg tcatctggtg tcaagccttg ttttgcagct
     6901 gcataaattt ctgcgattcc ttttccttcg ccattaccac ttgcactttg ttcgctatac
     6961 gcagctaagt taggcattgg taatggaaat tggaattgat tgatgacgtc ttcttcacgg
     7021 taaccaccga gcgttgaatc tgccgttaaa atgatagctt tagcccctgc ttctactgct
     7081 ttgttcaaaa tgaactcatt gaatctgtcg tctttactca tatataattg gaaaaactgc
     7141 ggtgcgcctg gcgctgcatc ggctgcgtct ttgattgtcg tatttgcata agtgctgatg
     7201 gaaaagattg atccagcagc agctactcct ttagctgtat cagcttcccc tttttcatgt
     7261 gccaatcctt gggccgctga tggcgcttgg ataatcggtg tatctaattc aattccgaaa
     7321 acagatgtat gcaaatcggc tgagtcgatt ccgcgtaata tccgtggcat gattttcttt
     7381 gtattaaaag aagtcgtatt ttctttcatc gtccactcat cttcagaacc accgcgaata
     7441 tagccaaaag ctcctgcttc catgcgctct tttacacgac cttctagtta ggcaatgttt
     7501 acaatatcga ttggatgttc ttcattactt gtatgataag tcatagtaga tccttctttc
     7561 atcttcttga ttacatataa atcatactaa acttacaaaa agtaagcaaa catttactct
     7621 cagatacttt tatcgctatt ctttccaaat aaatcgactt acaagctgat ctacttcttg
     7681 gttttcatga agcatactat gagaggcatt ttcacctgtc actacttttt cctctatttc
     7741 atttccgcgt tgcttcaaca acgcatagac cgctaatgca ctgtttaacg gtactgttcc
     7801 atcactcaag tctgtttcat ctagttgacc agcaatcaag aaaaatcgag tggttatagg
     7861 aatattaccg atcatttgct ggtaatcttg atagcggtta gaaacgacag caggcccctt
     7921 tgctaactca tctgtcagag actgcgcact atcatcgaca aaatcattaa aaggcgcgcc
     7981 aattgctgtt aatgtctgaa cttgtggcaa tgacgtatcc tgtccatacg ttcctaaata
     8041 gcgtagtgca ctaactcctc ccatggaatg ccccactatg ttgactttat ctatgccgta
     8101 gttttctttc agatacaaaa gacaagtttt gatccattct gcttgattcc actcgttatt
     8161 tttattatct tcaaacaata cttggaccat cggattgtct gcttttccag acaaatctcc
     8221 tgttgcttgt atttgtccat ctgttcctac tgttaaaacc aattctttta ctgcttgctg
     8281 atttttttcc aaacgccgca acatcccttt aaaggaattt tctgtcccgc tgtagccgtg
     8341 gaaaaaaagt gttggaatag tggttttttc tatcacttta ctggattctg ccgttttttc
     8401 tttatcagaa acttcagtag tatttatctt cgtcgtctgg caaccactta acgcaaacaa
     8461 actgataagg actaaagctg ctgcagttgc acgtttgcat aaatttttga ttggttctgt
     8521 catacacctc ttcctttcca tatagaaaaa agaaagactt gaaaggccaa tcatatgatc
     8581 gacatttcaa gtctctttat taatcgattt tatctacttg atcgaaatca agttctgtac
     8641 tggtttcacg tccaaacata tcgatgttga ctttcaattt ttctttttct ccgtcaactt
     8701 ctgttacttg tccttctaat ccagcaaatg cgccttcgat gattttcacg acttcgccaa
     8761 cttctacttc tagatcattt tgtcgcaggc tcataccgat agaacgcaag atatgattga
     8821 cttcttctgg aagtaatggt gctggtttgc ttccggctcc gtgtgaacca acgaatcctg
     8881 tcacaccagg tgtgttgcgg acaacatacc atgaagcgtc tgtcatgatc atttcaacaa
     8941 gtacgtatcc tgggaatgtt ttatgaacga tttctttttc tttcccattt ttgacttcag
     9001 tttctttttc ttcaggaaca acgacacgga aaataaagtc ggccattttc atactttgcg
     9061 cacgagattc gatatttgct tttactttgt tttcatatcc tgaatatgta tgcaagacat
     9121 accagttttt ttcaaaagat tccattgaag gctcctcatt tcattgtaaa ataaaaaaac
     9181 ctcagtacac ccgaagtttt tctttcgctt cattatagca ctaaaagtac gttgtggcta
     9241 gcgagttatt ttaaaatcca gccaaataag ctttggatgg ctgtatccat tacgtaaaac
     9301 atcaatccga aaataataga agtttcgatg actactaacg tatctttacg gagttgtttt
     9361 ctgcttggcc aagttacttg tttgatttca tcttttacgc tttttagaaa tttcatgaga
     9421 caacctccct tgctactgtt tatttcgttt ctttatgtaa tgtatattga ttacaatatt
     9481 tacaaaactt attgatttcc aaacgttcgc cgctttttcc ttcactgact gattttgtgt
     9541 agttgcgaga cccacaaacg gaacaagcga gtgctgcttt tttctttgcc atttacttct
     9601 gcccccttgc tgagaatcag acttatactt cgtaacagta tcacgtaact ttttacttgt
     9661 caatttgtga aataaactat ctattgtttt ggataaaatt atgatatgat taatttgaaa
     9721 ttaagctaaa atgagacaat tggaggtata gcgatgctat taaaaacact tgtatataag
     9781 aaaaaagatc tgacaaccgt tacagagact agtacattag aagaagcatt aaaaatttta
     9841 gaaacttccg gataccgttg tgtgccgatc ttagattctt caggtaatat tttccgtgga
     9901 aacatttaca aaatgcatat ctatcgtcat aaagcaaatg gcggtgatat gacgcttcct
     9961 gtcactcatc ttttgaaaaa cgctacaaag ttcatttacc tggatacttc tttcttcaaa
    10021 gtattcttta cgatcaaaga gcttccttat attgctgtcc ttgacagtga aaatcatttt
    10081 tatggtattt tgacacatag tacgttgctt aatatgctct ctcaatcttg gagcgtagaa
    10141 caaggaagct atgtactgac aattgcttcc acaggaaagc aaggagattt ggctgctatt
    10201 gcaaaaatca tttcaaaaca cagcagcatt gccagctgta ttactcttga tatcgaaaaa
    10261 gacgaataca ttcgacgtac attgatcacg ctaccggcta acactgaagc gaaagtatgt
    10321 gaaacgatcg tcaaccactt agagaaaaag aattataaag tggtagaaat tgaaaatttg
    10381 caaaaccaag aagcataatc aaaaagcgaa aaaagaaaac agctaatctg ctttcttttt
    10441 tcgcttttta taattagaca cgcttttcaa aatcaagcgc gcgatctaaa taatacatca
    10501 atggtgctga aacagccatg acgataaact cacttaatgc aagcgtgcca taggttgtcc
    10561 aaaatgcttg gccacctgtt ggaactaaca tataagcaat cagtcccatg ctgatggtaa
    10621 agaagatcgt gttcaatact aaacgcatct ttacattttt cactttgttt tgcaataaag
    10681 ctgtcaggcc taaagaaagc aatgtttggc cgccaccaaa aaccacatcc atgataccaa
    10741 aaccaaagaa ggcattatag acgatgaccc cgcctaaaac tccccaaagc aatttacggt
    10801 taaagacaac taaatgattc aaactttctg aaatacgaaa ctggatcggc cctgaggata
    10861 caggcgcaac taaaatagtt aacgctagat aaagagccat gatgatgcca tttacaacga
    10921 ttacggataa ccgttgtctg cttttcgttt tttgcatttt ctctcctctt ttctcctagt
    10981 ttttttaacg cgggatggtt gatgaaccgc ggttatgtga aacaaacaat aattataaca
    11041 gacttttcat ttatttcaat ccgtcttatc tgcttttaaa aaagcaaaag cttaaacaat
    11101 gtaaacgttt gctaaaaatc gtgggatatg gtataaagta agtgtaaggg gtcataagaa
    11161 ttcccagtaa agcagacgaa gtaggatctg caagaacaga attgttgtga aacttaaata
    11221 aataaaaaag gatgtgggaa tttgagcaac ctcttactag agaacggtct agcaagcagc
    11281 tgaagatcta agtggacatg ccgaaccttg gaacttctcc ttacgtaagt aatggatcat
    11341 gcgcttgcta ggcttttttg tgtttttcgg tcttcggacc tttttcattt tcctagactt
    11401 ctgctataat aaccaagaat taattttgta acagattttt ttgaaaaaac aagtttcttt
    11461 cattcaaaaa atagaaaaag cttgctaatt attggttaac cagcaaacag gagtattaaa
    11521 atatcttgtt ttattgaata gcaggaggaa atcatgaaat tccattatca tatattgatc
    11581 aatccatcgg caggcagcgg aaatggctat aaagtagcag aaagaatttt accggtatta
    11641 aaaaataagc atattgacta tacacttcat tatagtgaat acaaaggaca cgatgctgag
    11701 attgctgaaa ctttggcaaa agaaacattg attccttgga tagaagaaga acagaaaaca
    11761 atcgatactt tccccctttt gatcatcgta ggaggtgacg gcaccttaca tcaggtactt
    11821 gatactttct atcagatgga agtagaattc ccagttgctt atattccagc aggttctgga
    11881 aatgattttg ctcgaggggc aggccttcca aaaaatccca aaaaaggact tcagctgatt
    11941 ttagcagctc aatcaccaga aaaagtccac ataatggctt atgaagaaaa aataagtgaa
    12001 aaaaaaggaa tagctgttaa taatttcggt ataggattag atgcagctat cgtccatgcg
    12061 acaaatcatt cttccacaaa aaagcgattg aacaaataca acttaggatc attttcgtat
    12121 ttattctcta ttctccgtgc tttattcact caaaaaggat ttccaattct ggtagatgca
    12181 ggaggaaaac aattaagttt ttcaaacgca tttttatgta cagcaacgaa gcatcctttt
    12241 tttggcggag gaatcgcgat tgttccaact gctgatgcgt ctaaaccagt cattgatttt
    12301 gtcgtggtcg aacgaatcaa tttctttaaa atcttgtggc tcattctttt acttatacag
    12361 aaaaaacaat tgaaatcgaa atatttccat cactacacaa caaacagatt acgtatcgtt
    12421 tcaacaacac cgcaacatgg tcaagaagat ggagaagaaa tggaaaaacg accttttgat
    12481 atcacaataa ccacaactaa acagttgttt tggtgttaat aaaagaggtt ttgtcagaag
    12541 ctacatctgg aacaccgttt attcggaaaa aaggactgtg acacgacttt tgtcacagtc
    12601 ctttttttac tatgcagtta attctttgcc caattgggtt gccatcgata gtttctttct
    12661 ttacccaaaa taaattggat cattgaaaac accgcagcaa aagcaactaa gacacaacca
    12721 ttgaaccaaa aagattctgc aaatgtttga ttgtaactga gtgtttcact gatcaagtta
    12781 ttattttgaa caaaccaata tgttggtgtg aatgccgcta ttttgctaac catttctggc
    12841 aagtattctg ctggtacaaa caccccaccg ataaagcaac tgcctgtgat aaaaatatct
    12901 ttgatcccac cgctggtttc tgagtttttt accaatgaag tgatacaagc cgaaaagcta
    12961 atgatcggca ataaaaacaa gaaagtattt aaaatatgat accataccgt tatatcccac
    13021 gaggtgtgga tcactaacag aaccattaga agtaagaagc cactgaacaa cagcagcgag
    13081 taactaatca aactaaaggt tactttgcga ttcaagtttc gtttggtaat gggcgcactc
    13141 tggtttcgtt tactgatctc tttgcgatta aacgctagat tgatgacgct gaaaccgcta
    13201 aaaatggata gaaacaaccc ataagacaag aaattaaagg ttgtgcccgt caacagcttt
    13261 ttcatccgct gactatatcc cgcacttagc tcaacttctc cagtaaccga gagtgccatt
    13321 tgtgtctgtt ccatagctgc atcgattgtt ttatcttctt cttgaaacag aatcagtgtt
    13381 tgcaaaaagg tgttcacttg ctgtgtaaca actgttttag aaaaggcatc tgggcgactc
    13441 tgtatcttga tcgtcgccat ctttcctact tcgacttgtt cggtaaagtc tgcaggcaga
    13501 tgtaagataa tgtttacacg attaaaataa agagcatcat cgatttcttt ttgtgaggtt
    13561 ccatccaatg taacgactgt ttccttgtca ttcaaatatt tacgaaggcc atcgactaca
    13621 ggcgactctt cttcactaat caaggcgatt ttcgcatctt gcagagaggt attttcaaca
    13681 tcaatatttt gcgcaaaaaa gaatgtggca acaacagtga taattacacc tatcagtaaa
    13741 ttcgatttat ttgctttaag caatgtccaa atcgttttat aaagcgtcat aacgcacccc
    13801 tctttccatc caagcatttc ctaacgcaaa aaggaaaata aatccgatca accatagaag
    13861 attggtataa aaactagcca aatcagtgta gaaataaagt ttatacaaac tttcgctgat
    13921 caagttgacg agatttaatt gaccaacaat cggaatatga agatcaatcc aatacttcac
    13981 ttgttccgac cccatcatac cagcaaaaaa gctcatcgca atcgtcactg aaatcaagat
    14041 gctatccttt tgcaccagat tcatttttgg tatcaaatta ccaaccaatg tacctaacaa
    14101 aatcgcacac aacgacccca gagcggtaac aatcatcaac cattgccaac gttcaccaaa
    14161 gtctacttga tagataaaac gaaagacagc taacataata taaatctctg tcaaaacaat
    14221 cgtaaagctt gctgccaaat tagcgattga aactaacgat tgctttctag gaatcaagga
    14281 caagcgaata ccatttgacg attgatttgc ttgctgatcc tgtacattgc ggacccccca
    14341 catcgtcccg tagagaatcg ccattccaat cagagtgaag aaataaaaac ttttgaaact
    14401 catattacga cctgcatgaa cttcttgaaa agatacttct tgttcaaaaa cagtcatgat
    14461 gggcgcgaga tcaacgttct ccacttctgc cactttactc gaaattatac caatacgctg
    14521 taaaaattga tccatgacgt ttttcatcaa cgtctgactc attcctgctt gacccacatg
    14581 gagcgaaaca gatgaaccat caatgagata aaaaccagcc aaatcatctg catttagctt
    14641 ttcattcgct tctacttccg atagttcctg tacttcaaat aatggtttat cattgacttc
    14701 gacttgttct aagactgtgg taaaattttc cgaaagcgct gtttgatccg ctttgattac
    14761 aattccagta ttaatcgttt caagattgcc accttgatca atctcgccaa aggccgccat
    14821 aaacatcaat cctaaaagaa ttggaaaggc caatgtccaa aacaacatgg atttatttcg
    14881 cagcagtatt tttgtgcgat atttataaaa atgccaaaac attatttccc ctcctctagt
    14941 ctctcaaatc cttgccagta atctctaaaa agacatcatt caaggacgct tctttggttg
    15001 ctatttttcc gtaactgatc ttttcttctt gtaagattgt aagaatcggc aacaatactg
    15061 tatttagttc agtagttgtt acttggagct gacctttttt ataagcgatt ccatcagaag
    15121 ctattgttcg ctgaatcgct gacaacacat tttctgggag taatgggatg tcgatcgtca
    15181 aacgatccgc cgtccgtacc atatctttta gagattcttt ggttccttta gcaatcacct
    15241 gtccttgatc catgatcacg atctggtcgc aaagaatttc tacttcttcc atgtaatgtg
    15301 ttgtatagac aatggttgct ccttgtcgat tcagctcctt gatactttct aaaattttat
    15361 tccgactttg ggggtctaca gctactgtcg gctcatctaa aaaaattaac cgcggcttgt
    15421 gggcaatccc acatgcgatg ttcaaccgac gtttcaagcc accactaagt tctcctggac
    15481 gaaacgaaac atatttttct aatcccacta attgaatcac ctcttcaatc aaggctttcc
    15541 ttttctcttt ttcggaaaca tataaaccgc aaaaataatc gatattttct tgcacactta
    15601 gttcgtcaaa gaccgcaacg tcttgaggaa cgaccccaat cattgccttg acagcataat
    15661 tttcaggagt cattgttgtc ccgaacaatt taatggttcc tttgtcataa tttaacaaag
    15721 aaagcataca gttgatggca gtcgatttcc cactgccgtt tggacctaac agacctaaga
    15781 cttctccttc ttgtacttgc agatcaaaat gattcaatgc tacaaaatct ccatagcgtt
    15841 tgactaattt atcaatttcg ataatcatca tgaaaaactc cttccaaatt tcttgttgat
    15901 ctgactataa taaagtgcaa gaaaagaaac tagtgacgat tggctaaacc acacatgaca
    15961 tttgtcacaa tgaaggagtc tgctatgcat aaatctcggc tactcaacga aactagcttt
    16021 ctactggtta tctcattgct tttgctggta agtcaaggat tcgttgctat gcaagttatc
    16081 tatttattga tcgccgtttt attcactggt gtcagttatt tactgcctac aaagccaaat
    16141 tggattttcc aagttattct atttctttta tgtgcctttt tacctgatct tgtcctgttt
    16201 ctgccagcga cgatgcgagt gatcgcccct gaagaaagcc accttgatta cttgtttttg
    16261 ttaggttttt tgttgatttc gacggttggt aatcatcccc ccatcaaggt cgcctttgtc
    16321 gtaattttgc tgtttttttc cttttactta cgaaaaaaag atcaacgaac gaccgatctt
    16381 gagaaaaagt acattgtctc caaagatact cattgggaaa aacaacaaga gttatcggaa
    16441 caaaataaag cattggccct gtcacaagaa acacaattag ccttgcaaat tgtggaagaa
    16501 cggaaccgaa ttgcccgaga catccatgac aatgtcggtc atctgctgtc aagtgcgatt
    16561 ttacaaattg gtgcgcttga aatgatcaat caagaaccaa aactaaaaga accattagaa
    16621 aatttaagtg ccaccgttca cactgggatg gatcggattc gtcaaagtgt ccatgacctc
    16681 catgagacat cgatctcttt tcaacactcc ttagagtttc tgatcgctga ttttccttct
    16741 tctgttacga ttgaaggaaa cttgtttgaa ggattgaatg aaacgcagca aaactgcttc
    16801 ttaatggtca tcaaagaagc cttaaccaac agtatcaaac atagtcatgc caaaaccgtt
    16861 gttttacatt ttcgaacgtt gccggccttt tatcgcttgc aaatcacgaa tgatggcacc
    16921 agcccacaaa aaaattctgc tcccggtatt ggtttgaaaa cgatgcgtca acgtgttcaa
    16981 gaacaaaagg gacaagtcca tattttccaa gaaaaccagc aatttcagtt aacgatcatt
    17041 ttaccaaggg agggacacca atgataacag tagtcattat tgatgatgat ccatttgtga
    17101 cgaaatcgtt acaaaccatt ttagaaagca cgaaagagat ccgtgtgtta ggcattggtc
    17161 attgtgccaa ggatgcgcga aacccatcgt cccgatgttt tgctgacgga catccgcatg
    17221 cctaaacaaa cgggcatcga tgctgccaaa gaaattttgg ctaaatttcc caaagccatc
    17281 cttttgcttt tgacgacatt caaagatgaa gaatacatcc gcgaagcatt ttccatcggt
    17341 gtcaaagggt atttaatcaa acagaacttg caagcgatta ttccttctgt caaatccgct
    17401 tataatggac aggccgtatt tggtaatgaa atcatcgaga ctttcactca aatgatgaag
    17461 aataaaccga cgattgatag tcatgcttat gcttctttta gtgaacgtga gcttgcaatc
    17521 atcaaagaag tagctgccgg gaaaaacaat aaagaaattg cagatgcctt gtacttgagt
    17581 gacggcactg ttcgcaatta catcagccaa ttactagaaa agctagattt acgggatcgc
    17641 acgcaattgg ctatctattt ttatcagcat ttgcaataag tcttatctaa cacaaaaaaa
    17701 cctgaatgat gctccttcgc atcattcagg tttttttcac atcttctatt caattgtccc
    17761 gcaaaccatt tcctcacgat tgaaagaatc aaggattcgc agggctgcca ggattcgttg
    17821 gattgttcgg cgtgttaggc ggaaaaatag gcgccttgtc taacgttttt tctagttttg
    17881 attcttcacg atcgtctcgt tctacatcag gactttcatt caatttgaat tctttttcca
    17941 tctcatctaa ctttttaaag tcattgccag attcttttgc taatttcgct aatttatctt
    18001 cggtttcttt agccataaag taacgccccc cttttgattt cagcttagca tatcacactg
    18061 aaaaaacaaa agaaaacgct aaccaacgat catttttagc tatttctcat ctttaaaatc
    18121 aagcattttt tgccggtata aaatcgtagg gagaactgtt ttccatacca atcatcggat
    18181 ctactaactg gttatcgatc acttctgctg taagaacgaa atctttagaa acagcaggtt
    18241 ctacctcttc tttcttttct tctccaacaa atgaagaaaa cagatctggt tccactgttt
    18301 ccattacttg gtttttcgtt tcattcgtcc cactgtcatc ttctacaggt agcttttctt
    18361 ttacaacccg tggctctttt gtatagttcc catcttcaaa tggatcattt ccgaccaaag
    18421 aatcttcata agctgctagt ttggtccgga gagtgatatt cattttatca ttatccatga
    18481 tccttgattt caacgtagtc atccggcttg ctgattcatt cgctacacaa gtgacatagg
    18541 cttgctcttc ccctaacaaa atcaacagtt ccttactgcg agtcactgcc gtgtagagca
    18601 aattacgctg aagcatccgc tgatattgat ggaccatggg caaaataacc atcttgaatt
    18661 cactgccttg tgatttatgg attgagcaac aataagaaag agtgatttta ttccattcgt
    18721 ttcttttata agtgacctca tttgcatcaa actggataac taattcatcc actttatctt
    18781 cagaatcttt tgccaagatg atacccgtga tttctcccat atctccattg aatacattca
    18841 attcgggagt attgactaat tggaggactt tgtctcctat ccgataaacg gtgtcgttcc
    18901 aatgtacttc cttttttcca ggtttccctg gattgaatat ctcctgcatc attttattta
    18961 acgcatcgat ccctgcaggt ccccgataca ttggtgctaa tacttggata tcttgtgcac
    19021 ggaatccctt atttttcgct ttttccacaa ttttagagat caagggttca atttgataag
    19081 catcacttcg gaaataggaa cgatcttttt gattctttgt gaaatctttt ggcagacgtc
    19141 cttctttgat ctcatgggca agaggaataa tactagaacc atcaccttgc cgataaatct
    19201 gattgagttc cattttggga atttgttcga tttccaaaag atcatggagt acttgaccag
    19261 gaccgacaga gggaagctga tctttgtctc ctactaagat aacttgcata ttcgtcggaa
    19321 tcgctttgaa taatgtgtta gccagccatg tatcgaccat agacatctca tcaacaatca
    19381 aaagtccgcc ttctaattct ttcgtactga ctgaaggtgt tttttcccgt ccattcagcc
    19441 ccagaagacg atggatcgta ctggcaggca gacctgtcgt ttcgttcatt cgtttagctg
    19501 ctcggccagt tggtgctgca agtagaatag gaaaaatttc ttgggtatat tttgaaggat
    19561 ccaattccag tccgttcaac tctgcaaaaa gattgacgat tccgttgatc acagtagttt
    19621 tccccgtacc tggtcctcct gttaaaataa atagagggga acggattgct tcagcgatag
    19681 cttgttcttg cgaaggtcca tactgtatgc cgaatatttt ttcgatacgc cgaatattct
    19741 tctgcacttc tttttcagga taatggattt cttttttacg actgagaagg cgctggatcg
    19801 aattaccgat cccccattca gaaaagtaca aactgttttc gtaaagatta gtctcttctt
    19861 gttgtatctt tccttcttca acaagttgga taattacagt agcaacctga tcaggctgga
    19921 tttcaattgg gcgacttgtt tctaaaatac ggatcgtttg ctgaagcaat gtctccgccg
    19981 gtacgtatgt atctcctgtt tgaactgcat gctgaaaaat ctgatgcaag atagctgctc
    20041 gaattcttct cggtgaatct gctgcaatac cgatttgttc ggctagatta tctgcacgtt
    20101 tgaacccgat tccttctatg tcttcgacta gctggtacgg attttcttcg atgatatcca
    20161 aagactcgtt cttataggcc tggtagatac tgaaagctaa ctgactaccg aacccgtaac
    20221 gattcagtcc catgatcact tgatccatcc cgtggtttag ccgaatcgtc tcagcaagca
    20281 tttctctttt tggcttcgtc aaaccggaga tttgttttaa taccgaagga tcagcaatga
    20341 ttttttcgat agcatcttct cccagcaatt ctacaatttt ttctgctgtt ttcttcccga
    20401 ttcctgggaa tttttcgctg gaaagatacg ctacgatccc atttgcagtt gttggctttt
    20461 cttgctcata tctttcgagt ttaagctgcc ttccgtattt aggatgatcc actaattctc
    20521 cataaaaacg ataagtctca ttttcttgaa tatcgccgaa acttccggtg actacaatct
    20581 ctttttcacg gtaatcagct gtggtttcac tgatgtgtac caaaagcact ttgtaaaaat
    20641 tactaggatt ttgaaaaaaa atcgcggcaa ctgtaccaac gaaataaggc atttcttctg
    20701 gctgcatcgg aagccgcctc cttcttctat agtaaaggtt ctggtgctgt ttcagttcct
    20761 aaaaaatctg tttggttcca tactttcagt tcatatggca ataatctgca aggctcttca
    20821 gtctctaaaa tcgtcaaact actattgaac aatccaccca tttcacgcaa ctcacttagc
    20881 tcttttcctg tcatccattg aatggctgca gttaaagaag ctccatgtcc tacgaataaa
    20941 agtgggccat ctttatgtcg ggcaaccgca tctgctacaa cagtttcgat acgtgtgatt
    21001 gccgattcaa tcgtttctcc gtgaaaagga gaaggatcat acagatctaa atgattacgc
    21061 aaattcggca gattatccgg atatttctgg tacatttcat cgatcgactg accttctaaa
    21121 gtacccagcc ctagttctct tagcttatct gtataaaaaa tctctaccgg acgagcaagc
    21181 tctttgttga taccttctgc tgtatcacgt gctcgctttg ctgtactgga ataaattgct
    21241 ttaaaaggaa catattttac ctttttccca aatgctttga tttcttcgta actttgtggc
    21301 aaaagcggag aatcgccatt gctcccttga aaacgtcttt cctgattcca ttgtgtcttc
    21361 ccatgtcggg taaaatatag ttccatacgc agcaaactcc tgtctttctt ttattttact
    21421 ctataataaa ctgtctaatc cagcttgtca ttttcatagt gatgcgtcaa ttctaaatta
    21481 gggaatcctt gctggcgaag tgcttcatac actatcattg cagctgtatt cgataaattc
    21541 aatgagcgga catgctcatc attcataggg atgcgtaaac acttttcttc gttttcacgc
    21601 ataaatgttt ctggcaaacc ggttgtttct tttccaaata aaaagaagtg ctcttctcca
    21661 tcagcaaaat tttcgtcact atatacttta tgggcaaatt ttgagatcaa atgtagttta
    21721 cgattaccta aaaatgttaa aaaagcttct aaattactgt ggtaagtaat atttacatca
    21781 ttccaataat ccaaccctgc ccgttttaga tgtttgtcat cagttgaaaa acctagtggc
    21841 tcgattaaat gaagcggagt attcgtggct gcacacgtac gggcaatatt tccagtgttt
    21901 gcagggatta atggttcaaa taaaacgata tgattcatca ggatcattcc tctcatattt
    21961 atgttcgttt ctattttctg acaatttgat ttttgcataa aaaaaaacgt atcaactcgg
    22021 tgtcagtcac tgcgagtcgt tacgttagtg aagctcttct cactaacttt tatcagaaca
    22081 ggaacctgat aaaaaccaat gaaaaaacaa cttgttgcta atataacacc ctcaactttt
    22141 ttttgcaacc tctactcatt aaaaactgct agaaaaacgt tttctcttag ttccttttaa
    22201 taattctatg tcaattgtaa tcttcttcaa aggattctta tataagtctg ctttgattcg
    22261 ctcttctacc tgccattcta aaggtgacat ggccaaaaga tctttttgat tttcctctgg
    22321 tatctcaaat tcataggtta cacgctgacg ttcagttaat ttcattgctt cagcaaactt
    22381 ggctactaca cgttcattgg aataactctg tttttcaggt tgattcggat aaaaagcctg
    22441 acgtagttcc tttaaataat tttcttgtgg caccaccttc aacacttctc catcttctga
    22501 gagtacacgt tggaattctt ggtaatgaga aggcgaaaag atatttaaaa ccgcgttgaa
    22561 tgtttgatca gcaaacggca aattggtcaa atcagctaca caccaaaatg cttcggcaga
    22621 ttgttctgta gctgcgtaga ctccttcttt tgaaatatca aatccaacag cattttgaat
    22681 ctttttcaat tttgaaagtt cattcaagaa gctaccttct ccgcagccaa catctaatag
    22741 cgagacttct tcaggtaaat gctgcgcaat agtctcaata acgggctgat acatgccaga
    22801 ttggatcatt ctacgccttg gaacgaacat tccttgatcg tattctgttt taaccgcatg
    22861 ggataaaaaa taaagtgttc cttttttgga aaggtcaaaa cggtgattat ttttgcatat
    22921 caagccatta tcagactttt ttacttcttc ttggcaaacc ggacagcgga acagctgatg
    22981 attttctgcc aaaaactggc gtcctcggtc aatttttttt aacatagttc cccctcattt
    23041 ctgttttatc ttaccgttag atgctcactt tggcaactgc taaaaatatg atacaatgcc
    23101 tagaagaaag tgaaagataa aggagaagat tagatgatca aagaattttg cgctgaaaac
    23161 tacacatcta ttcctctagc aattgctaga ggagccgatc ggatcgaatt gtgtgacaac
    23221 ttagcggtcg gtggcacaac cccgagtact ggtgtgatcg aagaaacgtt aagttatgct
    23281 ggggaaaaag atatccccgt aatgacgatt attcgtccta gagggggcga cttcgtctat
    23341 aacgatatcg aattgaaaat catgcatact gatttgattg aagcaaagaa attagggacg
    23401 gatggcgtag tatttggttg tcttactcct tcaggctggc tagacgaaga ggccttagaa
    23461 ctattgatcg aaacagcaga agggttgcag atcaccttcc atatggcttt tgacagtatt
    23521 cctgaagatc ggcaattcga agcaatcgat tggctggtag aacatggtgt tgaccgtatc
    23581 ttgactcatg gcggtcctgc tgacaaaact attgtagaaa atttcccacg gcttaaagaa
    23641 ttgattgcct atacagatgg ccgcttaatc attttgcctg gtggtggtgt cactgcagag
    23701 aatgcagcac atgtagctaa agaattgaac gtaagcgaag tacacggaac caaaatcgtg
    23761 gatcttcagt tataatctta taaacaaaaa aacatttgca acaggcataa tgcttattgc
    23821 aaatgttttt gtttttttac ataaaatagc ccataaataa agaagcaata ttgaaataaa
    23881 tcagtacact cgtcaaatcg ctcaaagtcg tgataaaggg accgcttgct actgctggat
    23941 caaatcctag acgatccatt agcatcggga ttaaactacc tgcaagattc gccactgtga
    24001 ttgcaaatag catagccatc cctatgacaa accccaagat aaaattatgt ttccaaaaac
    24061 ctacgattag aaaaatcgtg atccccgtaa cagctcctgt gacaacgccg gtcaagactt
    24121 cagccaaaac aagtcgaaca aatccatgat ctttctcatc agaaatcgca agtcgacgaa
    24181 cagccacagc tagcgactgg gttccagcat taccggcagt tcctgtaatc agcgaaatga
    24241 agactgctaa aatactcgct tcacttacca agtcttcata gtgactgatt aaagaagcgg
    24301 tcgacatacc taaaaacaac agagtgatca gccaaggcaa acgtcgagac gctgccttta
    24361 ctggattttc attaatttct tccacattga ccccggcaag tcctgaataa tcgctagcag
    24421 cttcatcatc aataacgtcg atgatatcat cgactgtgac gattcctaac aaatgatcat
    24481 cataatcggt aacaggaaga gctaagaagt cataatctct aaatgtttgt gccacatctt
    24541 cttggtcgtc gcctacatga actgaaagca ctcgttcgct catcagatca gaaatcattg
    24601 cgtcgtcatc attcacgatt aggtcgcgca gagaaataac ccctactagc tgaccttctt
    24661 gattaacgac atagatgtaa tagattgttt cagctacatc tgcttcgttc ttcagcacgt
    24721 acatcgcaga gcgaacagtt tgattggcta cgatcgaaac aaattcagtt gtcatgatcg
    24781 cgccagccgt ttcatcctcg taatggagaa gttccttgat ttcactggca tcgtctgccg
    24841 acatcaaact taaatattta gcaatttgct ttttatccag cgtattaagc aagtcaacag
    24901 cattatctgt atacatctca gaaagcatat cagctgcata gctaggacgc atttcatcta
    24961 ggtattcttt catatgttcg ttgtcttctt caatcacatc gaacatatcc gctaattctt
    25021 taggcgacag ataggaatag atcagctgcc tgttctcttc tgtaagagat tggtagaatt
    25081 gcccctgctc atagatatgc atctctaaaa aactgtttct gaatgcctga atattatttt
    25141 cccttaaatc ttgagtcaac tgggcaaatc tttcctctaa ttcttgattt tcatccaaac
    25201 caatctcacc tcgccttatt cttcaaaccg tctcacaact gcctccatgt ctgcggctaa
    25261 aggctgcttg aactccagca actcttctgt aaatggatgg taaaaacgca gatcataaca
    25321 atgaagggct tgtcttttta ttcccagatc cattcgcccg ccatacatat catcaccgag
    25381 cagggcacag ccaattgcgg aaaaatgaac tcttatttga tgtgtccttc ctgtatgcag
    25441 ctggatatca actaacgcga tttctgttag tcgcttctct atccagtact cagtctgtgc
    25501 cgaacgtcct tcatcagaga ccattcgctt caatagcgaa gaataatctc gggcgatcgg
    25561 caaatcgata tgtccatgtg ccgataaatc tgaaagcctt ccactgacta aggcctgata
    25621 ttttttcaca aacttctttt cacgaagttg catatctaat tttgcgtgcg caaatccatg
    25681 ctttgcaaaa agcatcaagc cagatgtatc ccgatctagt cgcgtcacca catggattac
    25741 ttggttttcg taaccttgtt ttttataata agcctttaca cgattagcca ttgtcccatt
    25801 tggatggtat tgggcaggaa tagacgaaac gcctgctggt ttatttacta ccagaacgtg
    25861 ttcatcttca tacacgatat cgatcggtgt ttcatccaaa agtacggttt catgttctcc
    25921 ttcagcagga atcacaatgg ttaccttatc atccttagct agagaaaaca agacattttc
    25981 tacttgatca ttaactttga tttgaccgcc ttgaaatttt attttcgcta acagaccctt
    26041 tgagatccct ttttctttta aaaaatattt tacttgctga gaatgatctt tctcataatc
    26101 ccatgtaaac tgcatatcaa tcctcactaa taaaggcatc tttcacacga tgccaaaaat
    26161 gcatatgtcg ataagaagca aaatggatcc gttcttctgc tattcgataa taaattgagc
    26221 ggatatttgc ttttgcgaca ttcaattgat caaccgttac aagataatct tctgtatttt
    26281 ccaattttat ttctagccat tcatcatggg caatcacgat cggagaaccc aaagtacgaa
    26341 acactcgatt attcagtgaa gcaatctctg ccaactgaaa ggcattgata ctaggatgga
    26401 tcacagcacc gccgacactt ttattatatg ctgtcgaacc agtaggcgta gaaatcgtca
    26461 atccatctcc tctaaaactt tcaaacagct cgtttttgat gtatacatcg gctaccatcg
    26521 tacgattggc ccgtttaatc gttgattcat tcagtgctaa aaaatgctgg tccggtgttt
    26581 catccaaata actgatccga acatccagca agggataact aacactttgt tcccggttcg
    26641 ttcgtaagct gtctactagt tcttccagct cgtaatcccg ccaatccgtg taaaacccta
    26701 aatgacctgt atgcacgccc aagaaacgca catcattcag acaatgactg tagtgatgga
    26761 acgccgacaa taatgtgccg tctccgccga ctgagatgac caattctggc tcatgatcat
    26821 ctcgttgaat ccctgcttgt tctaaaagtg cgttcaaacg ttctgtcact tctatagtct
    26881 ttgcttcttt attatgaacg atcgctactt tcatcccctg cctcctctct ttcgctttct
    26941 ttcttcaaaa gcgttcgata gtagacatca tctgattttc ctcttccatg ggagaataac
    27001 cgctgtgctt cttggatttc ttcacggata ctggacatct cttcatccaa ctgataggca
    27061 gcttctgccg cacgctgaag tcgttcactc atttcttctg gaaaaacgcc ttgatattta
    27121 taattcagcg aatgctcaat cgttgcccag aaattcatcg caagagtccg aatctggatt
    27181 tccgccaaaa ttttcttctc accgctgatc agctgtacag gatactcgat caccagatga
    27241 taagaacggt agccacttgc ttttttattt gtgatgtaat ctcgttcttg gagaactttc
    27301 atgtcttttc ttttacggat gatctcaaca acttgatgga tatcttctac aaactgacac
    27361 atgatcctta acccggcaat atcagacatt tcttcttcta aacgtcccat tggaatatgc
    27421 cgtaattgtg attttgttac aatactatcg actggcttga ctctcccagt gacaaattca
    27481 atcgggacat gtcgattttg ttcacggaac tgtttgcgga tcccccgcag tttcactttc
    27541 aattctgata cagtttgttc atatggtgct aaaaatgctt cccaatctcg ttccatagct
    27601 gatacctcta cttcattaac attcattgtt tattctacca tatatgcaaa gttttttcgt
    27661 actcttgatt tatgcattga ccaaaaaaag aaaattaggc aaaatagaca aaaaggagtc
    27721 gatcaaatga cacaaatgct tgaaatcgaa tataaatcta tgctgacaaa gcaagagtac
    27781 gagatattca tcgctcacta tcaattaaca gataaagatt tccgtgtaca gactaatatt
    27841 tatttcgata ccgttgatga acagctgaag aaacaaaatt gtggcctacg gatccgtttc
    27901 gttggtcatc aagctgaata tacattaaaa acacctgctg aaaaagggcg tctcgaaaca
    27961 acggatacct ttataacaga agaagcagaa gcatttatct tcgaaaaacg tctgcctcgt
    28021 tcaggcgcag tttttcaaaa actttctgat ttgaatatcg atcctgcttc attaatccaa
    28081 accggaaagc ttacaacaaa acgagctgaa ttccctattg aagaaggact tttagctatt
    28141 gatgaaagct ggggagacaa tctacacgat tttgaactgg aactagaggt aggggatgca
    28201 tctgtgggaa aaattgcttt tataaatttt ttaaaacgtt tttctttacc ttatcgtcct
    28261 gctaagaaca agatccaacg tatgcttgaa gctaaaaatt agaaaccttt cattttcaca
    28321 aggcacttga gttcattttt ttactttttt ctgttaagtt ataggatgtg aaagaatcta
    28381 gtcactagtt gtatagaatc tattttgggg gagattcata tgatcgaaat ctatttattt
    28441 gttaatcctt taggggaata ctgtttcgaa atggaacaac agttattaca atttatcgaa
    28501 gaagagtacg ggacaccatc aaaagaaaag atgcaatttc gctttcttcc tttggtcaat
    28561 ttgcagacaa ttggggatgt catgcaacaa aaaggaattt ctcagaacaa tcttgaggaa
    28621 cgtaatcact tattctcaat gacttattct gcagcattgg actgcaaagc ggcgcagttt
    28681 caaggaaaga aaaaaggccg ccgttttttg atcaaattgc aagaagcagt cggctgtaat
    28741 gacataccat attctcaaga acttgctgaa tccatatttg aagaaatcgg cggcgatttg
    28801 aatatgttta aagaagatcg tcagtctgac ttcgttaaag aagtattctt ttctgatcaa
    28861 aaaattgctc gggaaatggg catcacaaaa cacccttctg cagtcgttta caattatgcc
    28921 tgcgaccgtg attttggtgt tttagtagaa gtaaaaggta caagtagcct ttggagaatc
    28981 acagagctgt gtaaaacaac agataactca tatcaagttt ttaatggtga acatttacat
    29041 acaaatgatt ctcagttcca ttcaagaact agccatttac acttgctttc taattaaaa
//
LOCUS       DADQDV010000031        27959 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.031, whole genome shotgun sequence.
ACCESSION   DADQDV010000031 DADQDV010000000
VERSION     DADQDV010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 27959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27959
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.031"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(424..1368)
                     /locus_tag="J8S10_001472"
     CDS             complement(424..1368)
                     /locus_tag="J8S10_001472"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HAZ9630059.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(1664..2608)
                     /locus_tag="J8S10_001473"
     CDS             complement(1664..2608)
                     /locus_tag="J8S10_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAZ9630060.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            2829..4043
                     /locus_tag="J8S10_001474"
     CDS             2829..4043
                     /locus_tag="J8S10_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAZ9630061.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            4065..6080
                     /locus_tag="J8S10_001475"
     CDS             4065..6080
                     /locus_tag="J8S10_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HAZ9630062.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(6163..7536)
                     /locus_tag="J8S10_001476"
     CDS             complement(6163..7536)
                     /locus_tag="J8S10_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HAZ9630063.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(7562..7846)
                     /locus_tag="J8S10_001477"
     CDS             complement(7562..7846)
                     /locus_tag="J8S10_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAZ9630064.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(7848..9863)
                     /locus_tag="J8S10_001478"
     CDS             complement(7848..9863)
                     /locus_tag="J8S10_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAZ9630065.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(10042..10347)
                     /locus_tag="J8S10_001479"
     CDS             complement(10042..10347)
                     /locus_tag="J8S10_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HAZ9630066.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(10436..11467)
                     /locus_tag="J8S10_001480"
     CDS             complement(10436..11467)
                     /locus_tag="J8S10_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HAZ9630067.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            11674..12549
                     /locus_tag="J8S10_001481"
     CDS             11674..12549
                     /locus_tag="J8S10_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAZ9630068.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(12701..13543)
                     /locus_tag="J8S10_001482"
     CDS             complement(12701..13543)
                     /locus_tag="J8S10_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAZ9630069.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(13635..15512)
                     /locus_tag="J8S10_001483"
     CDS             complement(13635..15512)
                     /locus_tag="J8S10_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAZ9630070.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(15509..16930)
                     /locus_tag="J8S10_001484"
     CDS             complement(15509..16930)
                     /locus_tag="J8S10_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAZ9630071.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(16933..20322)
                     /locus_tag="J8S10_001485"
     CDS             complement(16933..20322)
                     /locus_tag="J8S10_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HAZ9630072.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            20579..21970
                     /locus_tag="J8S10_001486"
     CDS             20579..21970
                     /locus_tag="J8S10_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAZ9630073.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(22043..22690)
                     /locus_tag="J8S10_001487"
     CDS             complement(22043..22690)
                     /locus_tag="J8S10_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAZ9630074.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(22698..23384)
                     /locus_tag="J8S10_001488"
     CDS             complement(22698..23384)
                     /locus_tag="J8S10_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9630075.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(23390..24463)
                     /locus_tag="J8S10_001489"
     CDS             complement(23390..24463)
                     /locus_tag="J8S10_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAZ9630076.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            24685..25359
                     /locus_tag="J8S10_001490"
     CDS             24685..25359
                     /locus_tag="J8S10_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAZ9630077.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            25364..26704
                     /locus_tag="J8S10_001491"
     CDS             25364..26704
                     /locus_tag="J8S10_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAZ9630078.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(26853..27839)
                     /locus_tag="J8S10_001492"
     CDS             complement(26853..27839)
                     /locus_tag="J8S10_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HAZ9630079.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
BASE COUNT         8161 a         5273 c         5062 g         9463 t
ORIGIN      
        1 aaaaatgata aacctctctc gaacggtttt ttatcaaaaa tcgtcatttt tccatcaaaa
       61 tctgcttatg caaaattata aaaaaatttt gcagtttttc ttactttttt tgtcgtttaa
      121 ttgaatgata aaaaccagtt tctttattca gttaatcaaa tatgaacgaa ttagatatga
      181 atcattgtat ttgccgttgc ggaaggattt tttaattaac cacagataaa cattgataac
      241 gattcgctta ttgtaatcaa cagattaaat ttcatatgtt catatgtacg gatacatttt
      301 cggaccgatt aattttaacc attctgttta tttgcttacc tattagatat caataaaaaa
      361 ctgcttaaca gctatttcag ctgttaagca gttttaggat ttttagttca tattcattgt
      421 ttcttataat acagtgttca atacttctct taaagcactt gttgatttgc tgaacattgc
      481 tttttcttct tcgttgattg ataattcaac aacttcacga acaccatttt cgtcaacgat
      541 tgatggcaca cctgtaaaga tatctttttc gtcgtattca ccagttaaat aagcagatac
      601 aggcaataca gcttgttcgt tattcaagat agcttttacg atacgtgcag tactcatacc
      661 aataccatag taagttgctt ttttacgatc aatgatctca taagcagcat tacggacttt
      721 atcagcaatc acatctaatt catcttgggc aatacgatgg tctttttcta caatttcaaa
      781 cactggttta ccaccgacag ttgtatgtga ccatgcagca acttctgaat caccatgttc
      841 acctaagata tagccgtgga cgctgcgtgg gtcaactttt aatttcaatg cgatttcttt
      901 acggaaacga gttgtatcca atgttgttcc agtaccgata acacgtgatg ttggcagacc
      961 agattcgttc caagcgatat atgtcaaaat atctactggg tttgaagcaa caacgataat
     1021 accgtcgaat cctgatccca tgatttcttt tacgatttgg cgcatgattg acgcatttgt
     1081 tttaactaaa tctaaacgag attgaccagg tttttggttg ataccagctg tgataacaac
     1141 gatatcagca tctttacatt cttcatagcc acctgaccat acagccacat tttcatcgcc
     1201 ccaagccata ccatctaaaa ggtccaatgc ttccccttct gctttttctt gattcacatc
     1261 gatcaatact aattcattag agattccttg gttgatcatt gcataagcga tacttgttcc
     1321 aacaaaacct gtaccgacga ttactacttt acgacttgtt tttttcatga ataaacagct
     1381 ccttttcata actatttgtt actttcatga aaagtatagt cttgtttatt cattttatca
     1441 acatgttaat tataatagtt gttattataa tttttgatgg aaacgaattc ctgaatacgc
     1501 ataacagata aatgacaaat gtttacacct atatcccctg ataatacaac caaaagttta
     1561 gaactgaaaa taaatccaaa aaaattcgct gcaacgatat aataagacag caatcgcacc
     1621 taaaacaatt ttccttcata tgctttagtg aaagattttc ttcttaatgt ttatttctcc
     1681 attcattggg agtacatgtt gaatacttct tgaataattt gaataaagaa gtcgtttgtt
     1741 tatatccgat acgattagcg atttcttcca acgaaaaact cgtttcttga atcagttcca
     1801 acgcaaagtc gaattttttc tttagaacca gttcttgaaa ggaagcatca aaatacattt
     1861 tcaatttatt actaagatag accggattgt agccaaaatg agctgctgtt tcttttaacg
     1921 tacaagaagt aaaatgctta tcgatataat ctaatactct aagcatctca ttttctgcgc
     1981 atccatctgc tgatgaaaag ctttgttgtt ctaataaatg agtcaattcg atcagtaata
     2041 gtgatgtata gagatttaac gaacggatct tatgactgta tgtatcaaaa taaatcaaca
     2101 gcatattttc aatcaaatgc gtcaaacgac ttgtttttcc gccgcgaaaa tgaatgaatt
     2161 gtgtatgttc ccctttttct tttgatgcat ttatcaaaaa agaagaaagt agattatttg
     2221 tgcttgccaa atgattcaat atctctgtag ataaggtttc ttcttttaat aagatgttga
     2281 ttaaaatatc ctcttgccct gtgtattcga ttctttgagt agcttcttta tcaatgatca
     2341 ccacgtcact ttcttccatc tctatccttt ctccattaat aatttgtaaa catgtaccgc
     2401 tatacatata attgatttca acaaaatcat gtgtatgctc gggaacttcc gcatatcgac
     2461 ggtgtttact gatatgaata tttccctgtt gaaatagatc ccctcggtgg atttttggcg
     2521 gtgtctgaag atggtaagct aagtttaaat cattgatatt cattccttgt tcacgctgca
     2581 gagtttcgat tgattcttcg ttacgcaaaa aaaatgtcta attcagctag ttccaattga
     2641 ctccctcctt tttgtaagcg gtttctttcg cttattagtt cacgctgtac tgctattata
     2701 tgcaaagcta tttttggttt cataaagact ttctatggtt gggacatgaa cttcctgtga
     2761 ttccgctatt gagagaataa ccacttcata ctatattttt gataagcgct tacaaaaatg
     2821 aaaggaacat gcttatgaat aaaaagatga tgaaattttc tctgctgtca gtctctctta
     2881 ttttgacttc tgctggtgca gtcacgtctg caattcccag tatgtcagct acttatgcca
     2941 cgcgttcttt atctgctgtt gaattattaa cgactgctcc ctcttttatg gtcactattt
     3001 ttgttttgat tagtagtttt attgctagga aaatcggaca aaaacaaact gtgatcatcg
     3061 gattagtgat tgcatcgatt tgtggtatcc tccccctctt ctcacaaagt tacagtattg
     3121 tcttagcttc aagagctgga ctaggtattg gctttggatt gatcaattct ttggcagtca
     3181 gcatgattgc tgccttttat cacggagatg aacgagcctc tatgattggt tttcaaagtg
     3241 catttcaagg atttggtgca gctttaatga catttgttgc aggacagcta gtacagttcg
     3301 gttggcaata taccttttta gtctacgcca tcagcttacc tattcttgtc ttgtttgttt
     3361 tgtttgttcc tacacctgaa acaactgaac ttcaatcgca tggcacagcc ccaacaagac
     3421 aagtaatcaa aacgaatcct aaaatgatta gttatggtat ttttctcttg ctggtcatcg
     3481 tggtatataa tgctgtatcg attaaattag ccacagtcct gacgacttat tctctaggaa
     3541 acgaaactaa tgcagcgaat atcttaacaa tcatgcaatt ggcaagtatg gctgccggag
     3601 tttgttttgg ctggcttcag acaaaagcac atcgctatat gcttacactt tctttactac
     3661 tgatgggaat cggctttgta ttgattgcca ctgtgataaa cctgtatgtg attgggtttg
     3721 gtgcgatcct aacaggaatt tctttttcgt tattcattcc ttacttattc aaccaagtaa
     3781 gtatccaagc gcccaagtac gcggagagtt tcaatacttc aatcttattg gttggcgcta
     3841 atttaggtac tttcattgca ccatatggtt tgctctttct ctcttttgct tctcttggga
     3901 gtaaaacact tgctgttttc gtcaatggca gtatcttgct gttgattagc gcgcttatta
     3961 gccttctagt agtacacagg acgaatagaa agacagtgat aagagtagat gaagaaataa
     4021 aagaacaatt gacaacaaaa taaatttgat ggaggtcgtg taaaatgaca aatgaaaaac
     4081 ataaagatag atggctttgg tatcctggag actttgagat ccgccatgga ctgctacaaa
     4141 atttccaacg ggaagaacga ggttttgact ggccagcgta ctggtacatg gatgattgcc
     4201 atcggaacgt caagtttaag agatattact ttcttgatca accttccatg tttaaagtga
     4261 cgatccaagg agttgggtat gtagaaatta atggacaaaa acatccatgt ggaaaatggc
     4321 tgacttgtcc agctggtaaa gcaaaaattc gtatctttgt aggacataca tcagggctac
     4381 cagcgatgtt tatcgaggga gacgaagtaa aatcagatat tggctggaca gcaagtaatt
     4441 ttattgaaga atatccagct ggctggagtc cgctttatgt cgatatcgca aaagatccaa
     4501 atcaaatcta ttatcaaaaa gaatgcgtcc atccagtcac tgaaacggag attggcggag
     4561 gaatcttatt cgattttggg cgagcagtga atggctgtgt agaactaata tctctggatg
     4621 accatatcga atctatcact ctatgttatg gagagtccga tgtagaagct atggatatcg
     4681 attattgcta ctataagcaa ataggaatga caagaaaaat gaaagctcgt aaacgcgctt
     4741 ttcgctattt gtttatacca gaggtttcta ctggaatggt tcaacttcaa gtttttcatg
     4801 aatttttatc tctttcgaaa caagctgctt tttcaagcga ttcttcttta ctgaatcaga
     4861 tctggtcagt atcagaagaa gccttcaagt tatgtagtga tttgtttttt atcgacggta
     4921 tcaaacgaga tcgctggatt tggtctggag atgcgtatca atcattcatg atcaatcaat
     4981 atcttttttt tgacgaggaa atcaataaac gaacgatatt agcattaaga ggacaaaatg
     5041 aaatcaagca gcatatgaat actatcgttg actattcgat cttgtggttg attggtatcg
     5101 aaaaccacta tatgatgacg aaagactatg aatttttacg catcgtctac cctaagatgc
     5161 aatcattaat gagatacttg atggagcaaa cgaatgaatt agggtttatt tatgggagag
     5221 caaaagattg gatatttatt gattggtctg aaatggataa agaaggaacg cttgctgcag
     5281 aacaagtctt attactgaaa gcctatcatt ccatgatcac ttgcggagat atcttagctg
     5341 aaacatatgg agagaacgaa aattatcata ctcatctcta tcaagaaaaa tatcaactat
     5401 tgaaacaaaa cctatttgac tacttttggg atgaagaact tggcgctttt atcgattgct
     5461 atgaatctgg gagaagaaat gtgacgcgtc atgcgaatat tttcgctgtt ttattcgatt
     5521 ttgctaacaa agaccaacag caatcgatct taaagaatgt cttattgaat gacactatca
     5581 cacagattac tactccatat ttcaaattct atgaacaaga tgctttatgc aaactcggac
     5641 agacgaatat cgtctaccaa acgattcttg attattgggg agggatgtta tctcatgatg
     5701 cggtaacttt ctgggaagaa tacgacccta ctcaaacagg aaatgaaaag tacagtatgt
     5761 atggagatcc ttatggaaaa agcttatgcc atgcatgggg agcaagccca atctatcttt
     5821 taggacgcta ttttatcggt ttgtatccaa caaagccagg ttatgaagaa tttatgatac
     5881 aacctaatct agattcattt gaaacactga attgtacgct acctatcaaa gatggaaaga
     5941 tttcgcttga aaaaacaaaa gataagatcg tgattacttc tgatagaaca ggcggaacag
     6001 tgaaaatgaa tggtaaaagt tatcctcttc tagcaaaaca gccacttgtc ttaacaagct
     6061 attcaaaaat aaatgcataa aacaaaaaac tgcttgcgac atatcagaag actttaaatc
     6121 ttcttctgat attgtccaag caatttttat tttgaagttt gcttaattct gttctttaga
     6181 aacaatgttt gttctttttc cggcaaaaag aaagctagat aatacgacaa gtaaaaagaa
     6241 agcgatgatt ccaactgtca aggctatttg accgtattct cctagtttcc caagtacaag
     6301 tcctggtact agataatcag tatcggcaaa tgtagaagaa gcgattttaa gatctcctaa
     6361 tactggaagg ataaataatg gcagccaact aatcaataag ctattgaaag cagaacctaa
     6421 taccgcccct cttctaccgc cagtcgagtt gccgaagaca ccagaagcag ctccgcagaa
     6481 gaaatgtcct actaccccag gaatgataac tgtagtttgc aagcctatca tagcaaacat
     6541 ggatagtgtt cctacaaaga agctaacaaa aaagccaatt aatacagcat taggtgcata
     6601 tggaaaaacg ataggaacat ctaatgctgg tttagaatcg ggtacgagtt ttttagcaat
     6661 cccttggaat gctggaacga tttctgccaa caccattcga accccttgaa ggacgataac
     6721 aaacccagct gtgaatgttc cagcttggat cagtgcaaag attacagcgt tgtctccatt
     6781 gcttagttct ctttcaacaa atccaggacc agctaacaaa gcaagtgcga catatacgat
     6841 cgacatcaag agcatgatcg atacagtaga atctcgcaaa aagctgaaac ttttaggaat
     6901 ctttatgtcc tctgtagaac ggtctttgtt tccaaaaaac tttccgatcc atccactaga
     6961 agcataaccg atatttccgg tatgccctaa cgcaacttga ttgtttccag tgatgttctt
     7021 cataaacggt tgacaaagag caggcgtaat agttaatagt gttccttcga agaccccgcc
     7081 taataagatc atccacaaat ttgcagtaaa ccccgcgctt actaaaatga ctgctgttag
     7141 acaagaaaca taaagcattg cttgacctgt aagaaaaatg aatttatatc ttgtgaatct
     7201 agcaagtaaa atattcacga tcatccctac tagcatgatc aaagcagtag gtgtaccgta
     7261 ttgttgcaaa gcaatcgcca ctactgcttc attgctagga actactcctt gagtatgcag
     7321 agctgtttgg aacatcgaag caaaaggggt tagtgaatta ctgattaaac cagcaccgcc
     7381 gatcagtact aggaatccga caaatgtttt gatagttcct tggatcactt ctgaaaattt
     7441 cttcttctga agaacgagac caagcagtgc aatcaaagaa acgaggatgg agggctgact
     7501 gacgattgac acaaacaaat tcaacaattt atccattgat agttcctccc ttgaatcatt
     7561 tttattcttt tgacaagatc ttcgttactt tttcttttac ttcttcgctg tcaatgatcg
     7621 attgcaaagg tacgagcttt tcatcaggta tagaagttag cgtatctttc aaagaatgct
     7681 caatgaagaa ataatcagcc atatcgctag atacacttcc aacatccgta tgacttactt
     7741 caaactcgtc cacatctgct ccaagatctg caagtgcttg tttgatgttc atctctacca
     7801 taaaacttgt tcctaatcca ctttgacata ctgcaaaaat tttcatatca ttcgtctcct
     7861 tttcttatga tcgctaatat ttcttctttt gttgatgcgt gtaataaatc ttgaagattt
     7921 tgtttattag aaagtagctt tgttaaattt gccaaagccc gaagatgtgc ctcattatcg
     7981 atagcagcta aacagatgaa caaactaatg ggatgggctg gattatcaag cagatccaca
     8041 ggttgttgaa gtttcagcaa agacatccct acttcgttta cgccatcttc tggacgagca
     8101 tgaggtaatg cgatgtgatc gccaatatgg ataaacgcac catactgctc cacgcgctcg
     8161 atcatagctt tgatataact ttcttctatt ttattttctg ataatagcgg ctgtgcggca
     8221 aatgtgattg cttcttgcca gttttttggt tgatccgata attggatcat ttcttctgtt
     8281 aataattcag atagcatagg acgttgatcc tccttctttt ctaaaagttt gttcatttta
     8341 cgatttaata cttgatagag cttttcttcg tctacgcctt cttttaattc gatataaggc
     8401 agtagcgccg acaacaattc ttgggcagaa ggcattgaaa atcctggtat cagccaatct
     8461 ctttgtactt gattgatcag ctgatttttt tccaagtcag tcatgattgg atgcagaaca
     8521 tagagagact ttttcttatc agtaagtgtg agaggtacag tagaaaaaat aatatcgtaa
     8581 gaagtttcgt caacctcgtg taagcggtca gctgaattag tctctgtaaa aaagatcatc
     8641 gggaataatt gctgaagttc actttttaag atcaatgaag agctaatgcc acttggacag
     8701 acgatcacgg ctcttatttt tctatttctt tcttctgcgt ccgcttttct gatctctccg
     8761 ccaaatagta tagtgaaaaa accaatctct tcttcaggga tgctcttccc tattcgtctt
     8821 tctaacggaa gtaatgcttt tcttgtcatt tcgtagatgg aagcatattg atgcttaatt
     8881 tgatcgatca tcacattagg taaataaaaa gaataggaaa tacgaaaata ggcagggacc
     8941 aagtgataaa agacattcat caataattca cgaaacgaag caaattctac ggccatcagg
     9001 aattccatgc gatggatgac ttctgaagaa cattccagca aaaaatcaag tgcaggctcc
     9061 tggacatctc cttcaacgat cgatgctaag caaagagaga aaaatataat ctccgaattt
     9121 tgatgttcgg aatagccaag gccagtcaat acttgtcgac taatgtcagt gactgcaaga
     9181 gaagccaaca gttcagcatc ttttaccagt tccatggatg tttttccaat tcgaatggtt
     9241 gtcaaactca aataataagc taattcatcc attcgatttg gtgcgaatcg aagatctgat
     9301 agtgaaatcg ttttatctag caaatctcta actttggcgt aataatcaat ggaaagggtt
     9361 gcggttaaat acgtgagccc aaatcttcca gcaagtgact gcatcaaacg agcagtgcga
     9421 ttttttgctt ctcttcttaa tattgcttct gaccctagca gcctaaaacc agttttccta
     9481 gtatacgaca gctgacaatc ttccacttct aattcatttc ttatcttttt gatatctgac
     9541 aggactgtcc ctttagaaac ctgaagaaaa tcttgaaaat gaaaaacaga aacagacgtt
     9601 gcagtcgaat aaaccatcaa ataaagaaga tctcttcgct cttgttcggt atacacagct
     9661 tcaaatcgag taatatccaa aaatttttct gcccagtcga ttgctcggaa tttctttata
     9721 cggatacggg tatcatccac atattcggca aaaggagtta attgtttgat cgcctcgctt
     9781 gtatttactt cgatgatctc tgctgctttt tctagactga tttctcttgg tgttttcagg
     9841 agataactaa ttttgtagtt cacagcgctg ttcacctcct acttatattc tagtatggta
     9901 gcgcttttaa atcgaggggt gtttggtaca acttacagtt ggattttttt tacgactgta
     9961 ccgaacgatt tctatcgaat ggatacagaa aaaaagcagg tgaccaaatg tctcctgctt
    10021 ttatgaattg atttcgtccg atcaatgatg atcatgttta ttttttgagg tcagttcttc
    10081 aaatttttct ttgacatctt caaccgcttt ttcgatatct ttttcaaagt gattgggctc
    10141 attaggcttt gtttcctctt ctacagaatt tgaaccagat aaagctgttt ctttattttc
    10201 tgtttcacca gagtttgtgc cagctaatga ttcttctttg tcttctgttt caccagaatt
    10261 agttcctgct aaagccactt cttcttctgt tttaggggcc attgaacctc ttaatcgttt
    10321 gtgtttttca ccgtcataat ttgtcatgtt ggttcctcct agtagttcta tactttttca
    10381 tcgtacaata agacagttta tgcgtcaaaa aacaaacccg attcttacaa atatgtcata
    10441 tttttccttc tgattcttga atgcttttga ttccttcttc caaaattttc atttgtaaga
    10501 ttgtttcttc atctttgatg actttttctg cgccattaac taatgtctcg taaatccctt
    10561 cgtagacacg gctgtaatca ccaacctcgg aaattacttt ttcttcatga taactccctt
    10621 gttcatctat ataggtcaat acaccataat gttcgggcaa atcgatacca aagtcttcat
    10681 gatcaggcat gtaaaacatt ttcagatgtt cttcttgtcg atcttttgtt tgtttcacga
    10741 acatcccttt ttttccgtaa acgacgaaac ttggacgttc tttgatgcgg aaataactgg
    10801 attttatcga aattttcata tttccataga aaaaatccag atcgaagtaa tcattcattc
    10861 gtcctttccc taaaagttga cgtacatcat agctgatatc atctggttcg ccgaaataag
    10921 aaagaacttg atctactgta tgacaagcat gtccatataa atagctgttc gcagtagaaa
    10981 attcatgcgt attttctggt acttccggtc tgaaataatc ataatgcatt tctacttcta
    11041 aaatatcccc taattttccg ctttcgatta ctttttggac tgtcaagaag tcagaatcga
    11101 accgtctgtt ttggtaacat tggataaata gacctttttc ttttgctaat gcaaataact
    11161 cttctgcttc ctttgacgtt tctgcaaaag gtttctctac tagtacattc ttaccatgtt
    11221 cgagtgccat ttttccatat tcataatgaa attgactagg tgtagtgatg acaactaatt
    11281 ggatctcagg atcatcccaa agatcagaca gctgatcagt atattcgatg tcttcgaatg
    11341 ttttccacac tggttcagat ggggaaaaaa tttttttgat attgattttg ttcgtaagtt
    11401 ttcttgaaaa aggcaaatga tagcgatttg tactctttcc attgccaaga taagcgattg
    11461 taagcatgag tggtgcctcc ttttattgat gttttcagta tatcctagaa aagcgcagaa
    11521 agtatttata atagctattc tggtaaaaaa gttcagaaaa acacttgtta tcattcggtt
    11581 tggtgaaatt aatgttcaaa gtaaggataa aaatcaaaaa gatagtagcg gaaccaagtg
    11641 tttatcagta agatagaatt tggaggtcag atcatgctta ttgaagaaaa actaacaaaa
    11701 caagagttgt ttaccacgac agagaaacgg attgtcgatt acatccgtag gaatatcgaa
    11761 gctgcagtct acatgacgat tgaagaatta gcaaaagcta cgtatacttc ccattcagct
    11821 atcattcgtt tatgcaaaaa aatgggattc agcggattta aagaattccg tttcgagctg
    11881 gggcgggaag ttcatcaatt gattgctcag ttcaatcaaa cgattgatcc taattttcct
    11941 ttttcaagtg aagatagcac tcagcaaatt gcaaagaaaa tggcggattt atcgatccag
    12001 tcaataaaaa aagcacaatt gcagattgaa catgaagatt tagatcaaat cggtaaagta
    12061 ttgaacaagg cacagcgaat ctttcttttt gcaaaaggtg attctcaaat cacggcaagg
    12121 aaattccaga ataaaatggt caagttgaat aagtttttga tcatggctga agaatacagt
    12181 gattcttctt ggaatgcagc caatttgact agcgaggatt gcgccatttt tattagctac
    12241 agcggtcgca tccatcatta tgaacgaata atgacctatt tgaagcatgt agaggcccct
    12301 accttgctga ttaccggaaa tcagcattca gaaatggcca aacaggctga tatgtgtctt
    12361 gttatatcgc aggaggaata tgattttgct aaagtagcga ctttctcctc tcaaattgcc
    12421 ttcgattacg tattaaatac gttattctca gtgatatatt ctcaaaattt tgaagagaat
    12481 atccgcaact tgaaaaacaa acaagaattg atgcaaaaag gccttcttaa agaatatcgg
    12541 aaaacttaag aaaagatcct catttagtaa taagaaagat agtgtttgat aggctctctt
    12601 tgatatcatc ataaaaacag gctgaagttt tctttttcaa acctcagcct gtttgtttac
    12661 ggaacgattc gaatagatat attatagaaa tgaggaatag ctaacttctg tttcttattt
    12721 tgaacgattg acgaaaaaga tatataagaa ggaggaaaat cagtatacat gcagctaaca
    12781 atccatacag gaaaaatcgt ttgttctcgg atactttctg tacttctttt tgaacttctt
    12841 ttgcatgata aggaacccgg tgccctctga caagtaagcg atgactgttg accatataag
    12901 gtgtacaagt taggagtgtc acgaaatcct gccctttttc gattctcaga tcttttgtat
    12961 cagtcggttc taccgtcttg atctgatcga cttgataagc gagtgtccgt ccattgattt
    13021 cgatatagaa agaatcacct aaagtcagtt tcggtaagtc tgtgaacaac tttgcttgag
    13081 gcagtcctcg atggctggaa ataacggcat gtgtattttc tccccccgta ggataagacg
    13141 ttccttccaa taatgaggca cctttttcta gcagcacagt attcgtttca tcaaaaattg
    13201 gcaaatggac attgatctca gggatcgtca aaataccgat cgtatgtttc tcaaaatagg
    13261 ttctatcctt tttcgcaggt tcttttttct tagtaaaggg atctgcacct ggatttccac
    13321 cttcttttgc taattgctgg tttttctttg tcatgttttc ttggatttta gccatgactt
    13381 cttcattttc tttgaccgct tgttgctgat aatgagagat gatctgctga tccagataat
    13441 tattcagcgc gtcgctaaca aatggataag ctagtatccc tattcctgag agaagcaaga
    13501 aaagcatcag cagatctaga agtttccttt tctttggttt catttgtgtt ctccttgtga
    13561 tgactgtttg ataataaaag aaaaaggagc atttgcgtaa tccgctgctc ctttttccaa
    13621 ttcttgcaaa aagactaaat ctgactgtgc ttgcgtctag caaagtacag tccagcaatc
    13681 agtagaagga ctactcctgc accgatatac acatagattc ccttaccgcc tgttgaagga
    13741 agtgtacctt tgtgtttatt tggtattttt tcaggagaaa tcaactgtcc tgctgttaca
    13801 taagattgtt catcgatagt aaatgctaca cggtttgtta atggaacata tttttctggc
    13861 gctttcgttt cttccagata gtacgtgcca tattttagac ctgtcacatc gattaaaccg
    13921 ttacttgtgg ttgtaaaaac cgttgctgat tctttcgccg atacccagct gacggctttt
    13981 gtggatgggt cgatcgataa atatttcgct gtgtcactat cttgatcacg aacgacgaat
    14041 tctgctccag caagtgtttg gtctgatgta acgtcaccat ctactttaac aaatcgtttg
    14101 cccccagtaa cgacatcgac tgacggtggt gtttgatcat ttgtatgccc gttatcgaca
    14161 tttgcttggt tagaaaatcc tttggttgga tctgcttttt cgttcaaatg catatagtaa
    14221 acgaatttca atgtaccgcc aggagttaat gaaggaatat aattcggatc aactgaaacc
    14281 gtgaatccgt ctgtttgctc agtgacagaa taatttactg ggtcgatttc tttatttcca
    14341 tcatataagg cataagcata cgttcctgaa gaatcattat caaatgttaa agcagcgtca
    14401 tgagtatcga taagtttgaa tgttgtgtac ttgttttgcg ttccttcttt atcagcgata
    14461 cctaatggga tattgacaga aatctcatat tgaatttttt caccgattgc gacatctttt
    14521 ccattcaatt gaggtgttgt tttatcaact ttagacgtat catttttgat ggtcttttct
    14581 actggtgttt ggctatttgc caggatctca aaaggcgtga ttgtttgctt ttcaatcatt
    14641 tccgcattat caggagcttt tacttcttct aaattatatt ttccaacttc taaatgatta
    14701 acgatcaact ggcctttttc aatagatgcc tcggcaaagt cattgttgcc gatgtcataa
    14761 gaatgaccag taatgaaatg tttggctttg gtttgatcag ttgtccaagt gtacaatcca
    14821 tctgtgacac tttggatgta ttttttgacg cttggtgttc cttcttcttt agaaataata
    14881 aattctgctc catttagtgc ttcgttttcg gcagtaccga tttttgtaac tttcaacgtt
    14941 ccatcattac cgactgtatt tttagggtag agatggatag tatctagttc ttctgtcccg
    15001 tatttataag agccatctgc ttgtttgatc atctcatata cagggaaagc taaaaccatg
    15061 tttgcggcag ctgacactcc gtcttttggt tcttctttga tcgtgtagac tgcatctttc
    15121 ccattttgtt ttttaggtaa agataaagtg acatttccat cagcatctgt cgttcctgaa
    15181 gcaactggtg taccaggagt caaagactgg actgcttgtt ttgctgcatc cacggacgct
    15241 cctttatctc gttgcgcata aaattcttga gtgacgttat aaactgaaaa tgaaatatcg
    15301 gctaatcctt ggtattgatc gaattcgctc atttctttcc cgctgttttg gattaaagga
    15361 tcgggtaaat cagtcatttt ctttttatga aggatgactt gagctgctgt ctcctctgca
    15421 aacacttttt ttgcgccgaa gctgtttgtg agtaatggta aaataaggaa aaggactcct
    15481 aacataacgt ttattttttt atgatttttc attttttcac tcctgttctt tttttgataa
    15541 acaaccagat tgcaaagctt gcgaatacca taccaacaac gcctaaaagt gtatttttcg
    15601 tttcgtttgt ttttggaaga aatggacggc tattttcttt tttattgact actttcaata
    15661 tactgtccgc ctctttatcc tcagaaagaa aagttgaaat ggtaaacgga atttctgttt
    15721 cacttaaaat ataaccagaa ggtgcttcga tctcttttaa tcgataactt cctgttttca
    15781 acccggaaat tgaaaaagcg ccatttttat cggaaatcag gtgaagcgca tctgattcgt
    15841 tctttgtcca cttgtatccg ttggctgttt gctggaggta atttcctgct ttgtttttaa
    15901 taaggaatac tgcgccagct aatcgtttat ctggtttatt tgtctcgatt ttgacaaatt
    15961 gcttactccc tgtatataca gagactttct ttgtactgac accaaaacca aaatccagtg
    16021 ttccgttgtt gttgatttcc ttgttcgcct gtgctgtact gcttagctgc atctgataag
    16081 aaatggtcag tttttttcca gcatattttt ccaacgaagg gatcgaaaat aaaacatcaa
    16141 atccgtgagg tttcttgtgt atgacaaagc cttctgtcag cttttctcca ttcgatgaaa
    16201 tcgttaaact attaggtaaa aacgttaatg cttcatccgc actatctgac aattcgaact
    16261 tttgatagtc aaggatattt acaggaattg tcgtatgcaa ggaataagtg attttttcac
    16321 caatcgtaaa atcatttcta ggctcttcta ataccttctc aaaaggtgga tcagggtagt
    16381 cgttttcttc atttttagga tacaaatgga tagttgaaag tttttgattg ttttgtccat
    16441 gtacaggaag aacaactacc atattctctg ccttttcttt gacgacttct ggtactttgg
    16501 attcaatgaa aagatacgct ttatctcttt tttcttgatc tttagcggcc agagaaaaag
    16561 aagcgatacc atcttcgttg ttaagagttg tagttgttgc ttctgcggta aacataccgg
    16621 aagacgcacc gttttttgcg atctctgctt gtgcttcttc taccgttttg cccttttccc
    16681 gtagatggta aaaagaatct gtgacatcat aaacttggaa tgtgacacca tttaatcctc
    16741 gatacgtttg taataaagct ttttcttgtc cgtcatttgg atgatttttc ggcagttgcc
    16801 cgtttgggaa aagcaatttg tgtaaagtaa tctgaaccat ttctgtttct gtttctgttg
    16861 ctacctgagt aaaagctggt ttaaatagta acaagaagag acacatacta agccaaccaa
    16921 gttttttcat atttagctgc cccctctttc ttttttcaaa aaaagatacc aaatagaaaa
    16981 cgcacaacca atcatcccta ctagatagat tcctaaacgg ccaattcctc ccgtttcagg
    17041 taatggtact tttgcctgat tcgtgatgtc taaagaaatc tggttgtttt tggctcctgg
    17101 tgacagaaca gattcatgat cttgtccatc cacttgaatt gacccatctt cgtgtataac
    17161 tatagtaact ggctctttta gaccttggta tccttctggt gtaaaagttt cggtcagcgt
    17221 ataagttcca ggttttaaat tttcgaatag aaaggtatct gtttcttgtc catcttttgg
    17281 cgattctaag tccatttctg gtccctgcag tctgaatttt gctcctttta atgtctgtcc
    17341 gttgtcttct tttttgtgta ccgttagatc aaacgctttt agtcgatttt gatgagtgag
    17401 cgtccataca ttatttgtca tctcggtatt ttttcccgtg taaatgattt ttccatattt
    17461 atcgatttgg aattcataat ttcccggcga agtatcatat ccggcaggac cagctgtttc
    17521 aacgactcga tatttaccag gtgtgagtga atcaaaactg gcaagacctt tttcattcgt
    17581 tgtttggctg tcaattggct gataagtacc atttgcttct tttttctgta gggaaaatgc
    17641 tgctccttta agatttatct ctttgtccgt cccttgcatc gcatacttac gtactgctac
    17701 aggaacttca acaaaaggat tttcaatagt caactggatc gtatcatcgg aagtagtgac
    17761 tgtttttcca tcaatggtta ccgtaccatc agaagcgatc ttgatttccc aagtagtctt
    17821 tttgcttaat ccatgccctt ctggagcttt tgtttctgtc agcgtatagg tcatttcttt
    17881 ttgcaatttg acattttctg gaagagaata ggttccgtcg ccatgatctg ttagtaaagt
    17941 atcaatagaa tctcctgtta atttgaaaac agcgccaata agatcctttt cacctgtaga
    18001 ggaatttttc gttattttca agtttaacgg tgtgaattgt ttagtatttt tccatgtcat
    18061 tgcatctatt tgttgagaat cgtatcctgg tacaggtaat tctttgattg tttggtaact
    18121 gaatgcttga ccttgattat tgtattgagg tagtgataat atctcttgat aactttctcc
    18181 gctatttgca gataatttgt caatgtctgc acgttcccac gtatttgttg tatctttagc
    18241 tggtttaatg attcgaatat atccgttttt ccaagctgca gcatttgtcg tatgttcccg
    18301 ttgaatctca aaagtaactt gatctggacg atcagctaga ttgttgtcaa attcttccca
    18361 taactttttg atgtgaagac tgactccggg agctttagca gatggtatac cgaattcagc
    18421 taattcattg gtatcaatgt ttggctggaa agttgtcctg ccgttcattt gataccagaa
    18481 atttggatgg aagtcctcat tttctgtttg gattctcact tggtaatgga tttggatttc
    18541 ttggtctttt cctaaataga tctgattgct cttgatggta tttccttcta tggaaataga
    18601 tggagtgacc gttgtaggac ttgtccccac actcttgact gaaagtgtac caggctgata
    18661 aatgaatggt tctgcgattg gatcatttat ttgtccattg cttacagttg ctgagatctg
    18721 tacagctttt ttggctaggt attcagagat atctgttgca tgatcagctg attcatagta
    18781 aagatcgcct ttttcatctg atgaaaccat ttgtcgcata cgagactcta cttctgcttt
    18841 tgagagacca gctgccggat cgctttgaag ttggatgcca agaccatgta tttcgattcc
    18901 tcgttctttg agtgccatcg cttctccgat ggttgcgata aacgtactgt cgattcttct
    18961 ggatagattg ttttggtcag gtgcatcata gattcttgag attagagaag tatttcccgg
    19021 ccgatcttgc gtattagaaa actgagttcc gtaataattg ctgcttgatt gtgcgtgtac
    19081 ccgctgtact ttataggaaa atgttggtac accatccgtc agcaaaacga tcactttttt
    19141 atgtccattt ggaacggata gcatgcttcc tgcatctctt agtgcttttt gtgtaaaagt
    19201 accaccattt gtccgtgaag gtgtaatgga ttttacttga tttttcactg aatcaaatga
    19261 acccatctgt actgcaccgt tactgtagct atatccttcg cttgagtagc cgacatatcc
    19321 catattgatt ttgtctgtga taccgctatc tgctaaagta tcgacaaaac gatcgacacc
    19381 aatctttact tcaccgatcc gattattgtc gttcatactt cctgaccagt ctacgaccaa
    19441 tacgagatca agaggcgtga tatctttttg tacatttcca cgagcattca aataaacatc
    19501 aaacaatccg ggtgtacttg tttcctttgc atactttcgt atcgcatagt ctgcttgatt
    19561 accggttcct ccatattcga tatacgaatg ggtccgatca ttaggatctc cattccaaga
    19621 atttatacca tcccattgat ttgttccgtt tttattgcct tgatgatcaa gaacatttgt
    19681 atttcctgta ggttgccaac tggctttagg ataagtgccc tgatcatctg ttgtatattc
    19741 tgtaggaatc gtttgattag atggcacact cacagctggc aaggataatg taggcaatgt
    19801 aaatgggctg acagaatttt cgttttcttt tgatgattct tcttctattt cgtctggctt
    19861 tggtactgac acatctgtat ctttcttatt ttctgtctca tcaataatgt catattcttt
    19921 attatcgacg atcagcttgt ttgcctggct gtggtaaagt gctggatcga ttggaaaact
    19981 cagatcgata gtttgtttag tgtttgatga gatttccaac gtaattttcc cgctatttac
    20041 ctgataagca tagccatctc cttcttttct ttccacatca cttaagtaat tttcgactag
    20101 accaatttct ttttctatct tttcagcact ggtgttattc gcatttagct tgatgttcag
    20161 tgcttttttt ccagactgat ccgaaatgac ttcagctgaa attgtttcta aaactgttgg
    20221 atcatctgta gtgtctgcta ttgcagataa tggcacaaag tttgataaac tcaatattat
    20281 cagcatgaaa ataactttca gtttcttccc tgtggtcgtc atttttcccc tcctttttct
    20341 ttttttctgt tttgacgtga atagtgaaaa ttattaaaat aaacaggcgt tacataattt
    20401 tatttatttt aatatgataa ttattatacg aagggcgcta aagggaatca caccaatttt
    20461 cataccaatt ggtttcattt atgaagttga ttccttcgat taatgagcgt ttcattgaaa
    20521 gaaaagggtt gagggagaaa aacatatgat caggttgttg gaaggaaact atagaaagat
    20581 ggaaaaaatc attcgaattc tgtccatttc tgacaagtgg atgactaaaa aagaacttgc
    20641 caaacgaatt ggtagttcag aatctacatt tgtaaggtat atcgaagaga tcaaaatccg
    20701 ctggggaacg gatgtaacga ttcaatcttc acaaaaattg gggtatcgtc ttgaacattt
    20761 gaatgtacca gcttatttaa atgttctgat ggaaatgtcg caaagttcta caaacagtcg
    20821 tttattaaat gagattattg tcaatccggg taaaacgatt gagtattatt gtgaaaaaat
    20881 ttccatcagc cggtcttctt ttacacgtaa gttgaaacaa tgcaatcaaa ttttagaaag
    20941 ctatttatta aaagtgatcg ttgaccaagg ttttcagtta actagcctta aaagtgagct
    21001 ccagttgcgt atctttgtta cctttttctt tttaagttac tacggaagac gcacgttgcc
    21061 atttccaatc gaaaaaaaga agatcaaaga aattatggtc aagaataatt gtcagatgaa
    21121 tttgtttcag gaagaaagcc catatgagca atctttcttt attatgtatt ttgttgtgca
    21181 tctcatgaga gaatcccaag gaactccatt tgaatggaaa gctggagact cttatgtaca
    21241 gttgataaat atcgataaaa aagacttctt aatcttgaaa aatctcttag gaaaattgaa
    21301 gtacagcagc tatataaaag tagtgaacta ttttgtcaat acgatttttt cagaattttc
    21361 ggagaaagaa aaaaatgaaa tcagtgagca gatacgaaaa aatatgtcct actgttcgtt
    21421 ttcatccgct gattgcaaag aaaaaaacga agaatatgtt gttcaattat taacgcaaat
    21481 ttattttttc tcccgtattt tcccatacga tacgactcat ttgacgatcc gtgcaactta
    21541 ctttgcacag cagatgcaac accgccagat acgtctatat gctggatttc gtgcagaact
    21601 tcaattttat tccactctac tgaatcagaa tctgatttat tatttatcta gctatatctt
    21661 ttggatgctt atcggtaatc ctgaaattca ccattatact tctgataaaa aaatactgat
    21721 tatcagcgac ttaagtcttc gacatagtca atatattgaa gaatatatca gtgatattct
    21781 tgctgtgcat aaaattcact ctgagacaac tgctattact gaagatcagc tgtcgaaata
    21841 caatcttctc gagtatgatc tgatcgttac gaatcaaccc attttgaatg cccatgttcc
    21901 tcatatattg attgatgata gtgtgtcatt cgcaaatgaa gaagaactca tccgcttatt
    21961 cgagttatga ataatcaaaa aacagctatg tataaaccac cctgataaaa atttcaggac
    22021 aaatacacat agctgtttct ttttattgta ttccttcagc aatccaacga gatttatagc
    22081 gaaagtcttt taacaactct tcttttgtcc aattatttgc aatgagatcc gtcaaagtgt
    22141 tcattacgag ggtcatggaa aagtatagga aactaactgc ttcttccgac gattgaatgg
    22201 agaaatgatt gattcttaat aattccagcc atttttcgtt cattggagaa tcagccgata
    22261 gttctctacg tttggttgtc tgctgatcat ttcgctgggt taacaagtat aacctttgcc
    22321 aatagatact ttcgtgatct aagtcgcagc accactctaa atatttttcg atccccaaaa
    22381 agaaatgttg tttgttttcg ctaatgaatt ttaagatatc ttgatggact atgtgagaac
    22441 tgcttttgat cgtatacaaa taagcatctt ccaaatcttg aaaatattta taaaaagcac
    22501 cgcgcgacat ccccatcttg tcaacgattt ctgagacttt gacttggctg atgtgctgtg
    22561 agcaaaatat ctccagtaat aggtcatcga ttctctgttt ctttgcgttc gataaattga
    22621 aaaaagtttc ttttggcatc cacatctctc ctttatctct gattatacgt ggatagccct
    22681 tcattgtcat gaaggattca ttccttcttt ttctcttctt ctgtcaagta cccatcttcc
    22741 attcgataaa cgcgatcact ccattgaatc atacggacat catgagtaac cataatagtc
    22801 gctttttgtt tctcatgagc ttctttaact agtaatttga cgacttcata tgcatgatct
    22861 gtatccaaac tagctgttgg ttcgtctgct aagatcaagc ttggctcatt atataaagcg
    22921 cgagcaattg ccactctctg tctttctcca ccagaaaggt ctttaggata actattttta
    22981 agtgactgga tatctaaaga ttgcagcaag gaatcgattt ttgttgaatc ttcttttttt
    23041 gaagtaactt ggtcaactag ttcaaattgt tcctttaccg ttaaaaaagg aatcaaatta
    23101 gagctttgga gaataaatcc tatttcttta aagcgtaaat ctgctcgttt tttttctgga
    23161 agctcagtta gtgagtgacc gttgatcact atttctccgg aagtcggtgt ttgcaatcct
    23221 cctgaaatgg taaggaaagt acttttacct gaaccagaag gaccaatgat gctgacgaat
    23281 tctccttcct ttacataaaa atcaattgct ttcaaagctg agacctttgt atgaccagaa
    23341 ccaaatgttt tggtaacttt tttcatcgtt aatatttttt tcatttttat taacctccta
    23401 ttgctgtaat tgggtctact ttggttatcg tacgtatcga aaacaatccg cctagcattg
    23461 cgacaatgat caaaatccca ctatatagca accattgtga ccaaaaaaca gcaaaaggca
    23521 tcgcgcttgg taaaatcaga ctagtcaaat aagcaaacaa aagagcaagc agaacgccta
    23581 ccaccccaac aataaaggac tgtgctacta aagatttagc gatgaagaaa tttttgatcc
    23641 cttgtgcttt cattactcca aaaatagcag tcttctgaag tgtcatcacg tacatgaaaa
    23701 taccgaccac ggcagcaacc actaagaaca aaaagtatat catcgcattt aaggtcatat
    23761 tttgggcaga atagccagga atactttcaa tgaatgtccc aatagttaat aactgtagac
    23821 ccttcgatgc tttttctttc gaaattttag ctgaatcctt tattacgatc ccattgatcg
    23881 gctgttcttc ttcagaagca aacggctgtt gtccatactt caaagcagtc cacgtatcta
    23941 gggacgcata gatgacggga gaaactgtgt aataagtttc aggaaagata ccgacaatcg
    24001 tcaaaggatc gtcgtaactg ccaattttga tcgtatctcc aattttatag cctgaatcag
    24061 ccagattttg agagatgatg atttcattct ttgttttaaa ttcatgccct ttcgtgagtt
    24121 ttggtaataa aaatgcttct ttcgttgtgc cgaaaactgt aacattttct ttgttttttc
    24181 ctttgattgc tccgctgtac aatccgattg gtgctttctc tcctccttca atgtatttca
    24241 gatctcctct tgttaattgt gaagctgcaa atacttgatt tgcatcctcc gacaaaacaa
    24301 tctcttgtgc gtcccaatca tcgattgctt ttttaaactc ttctgaaagt ccattcgcta
    24361 gtcctgacaa catgaatacg acatacgcaa tcaagaacat aataccgacg atcaagccat
    24421 atcgtaattt agaatagcga atttctttga tagctagaaa catttgtttt tcctccctat
    24481 gatagattga tagtgacaaa atgtcacttg ttgaatagtg taactctaaa gtgacaattt
    24541 gtcacttgtg ttgttttttt cttatcaata aattgtctaa gacatctttc gataaaacct
    24601 taacatgagt cataaaaaat ttatttaagc cttatttatg ctttccatga taaactaaag
    24661 tgaccaaatc aatgaggtgg gaaaatgatt aaactattag tagtagaaga cgataaagta
    24721 ttatccaata atataaaaga aatactcgct gcaatcggcg agataacaca agtttatgat
    24781 ggtagtgaag gactgttcga gttggaaagt ggagtttatg atcttgcaat cttggatttg
    24841 atgatgccgg aaatgaatgg atatgaagtg ttagcaaaaa tacggaaaga aaaaatacag
    24901 actccagtat tgattttgac tgcaaaagat agtttggaag ataagattga aggatttgaa
    24961 cgaggtgcag atgattatct aacaaaacct ttctatcgag aagaactgat catgcgcgtg
    25021 aaagcattat tgaaacgctc gctaggtctc tttgatgaaa atgttctgaa gtataaggat
    25081 atcagttgtg atttaaaaag caatgaagtc ttgtataaag aacaagtttt gcccatacaa
    25141 ggaaaagagt ttgaattgct cgtttatttt ttacaaaata agggaatcat tttgacaaaa
    25201 gagcagatat ttgaccggat ctggggattt gattctgata cgacgattac agttattgaa
    25261 gtttatatga gcaacttacg aaaacatctg cgaagtactg gattggataa agaaatcaaa
    25321 accttacgta atgtcggtta tatactgcaa agggtgtgat gcaatgaatg gagatattac
    25381 acgaaagcaa cgtagtcgct tttttgcgac aaatgtagca gcatttgctt ttatcttttt
    25441 tcttttggga ttcattactt tacagatatt aaaccaatct gcatacagag aaacagatct
    25501 gtcattagag aaaataaatt ttgattctcg aacagtacaa ttagagatac aaagatatca
    25561 gcaaggcgat ccctttttaa acccgactca aacggaacaa aacagaacaa acatggaaca
    25621 gccattaatg gaaccatcaa atgaccgttt taacactcaa gtgatcttgt ggtctaaaaa
    25681 tggtgagata ttgaataaag cagctattgg tgggcgtttc aaccaaatca aagaattaaa
    25741 aatggatacg aaaaatctga ataccatcca aaatattgaa ttaaatgaag acagtggctc
    25801 atctgccctc tctttccgtt cgattacgaa aaaagcggag acgaatcaag atggcgttgc
    25861 ctacatccaa attttagaaa atacaaatca aatcaagaat tcattagcga cttttcgcac
    25921 gattatgatt ttgtgtatga ttgttttttg gattctctct attggtatca gttattactt
    25981 gtctagtcta agcatgcgcc ctattattct ttcttggaga agacaaaaag aatttgttga
    26041 gaatgcttct catgaattgc gcacaccgtt aacgattatt caaaatagtt tggaacatct
    26101 ttttaccaag cctaatcata ctattattga agaatccgaa agcatcgctc aagcattgtc
    26161 agagacgagg cgcctcactg gattgacttc ggatttgctg acaatcgctc ggaatgattc
    26221 tgatcagcag ctgctttcaa agcaaatgat caatacacaa gaatatatcg aacaacttgt
    26281 taaaccattt caagagatgg ccatcataga tggaaaagag tttattctcc ataacgatgc
    26341 aacattagaa gtaccaattg atgaaaaaaa aatccatcaa gttttggtta ttttgctgga
    26401 taatgcatta aaatatacga atccagaaga taagatcatt ttggattcat ctgttaacca
    26461 taaagaatgg ctgattcacg taaagaatac tggcccttct atcagtgaag aagatcaagc
    26521 aaggattttt gatcgatttt atcgggaaga tcaatctcgg gcgaaagaga ctggcggata
    26581 cgggcttggc ttggcaattg caaaacaggt aatcgaacag catcatggac agatttctgt
    26641 atccaattat cttccacaag gagtcgattt taaagtccaa ttgccgttga agcctaaaaa
    26701 ataatgctta tccctaaaaa agggctgtga caaaaatctt gtcacagccc ttttttgttg
    26761 cgaataaacg gtgttccaga agtagcttct tcggaaataa gccgaaattt ctttaagctg
    26821 accacttctg tcacaacctc tttagcttac gcttacgatt ttttattgcg gtcttcaatg
    26881 tgtacatcac cgcttgtgtc aatatccaat tcttctcggc taacatcttc tgtcactttt
    26941 tcaacatctt catgttcttc tttatgaatc ccaacttctt cacgaataac tgtatgtttg
    27001 cttacatcta cttgctcttc tttgattggg atagtaatcg tgtcatcttc caatttttcg
    27061 tctgttccct gtgaagattg atctgttact ggtttgcgtt cgatgacgat ttcttcacgt
    27121 ttgaccggta cttctaccgt ttcagtatcg ttgaccacat gtttgtggat gtcgacttct
    27181 ccagttgtca catcatgtgt atttacatct aatttttctt cttttagttg aattgtatca
    27241 tcatctagat ttggtttgcg atcgatgtct tcagtcttgc ttgtacccat tgtatcagtc
    27301 tcgccaggta cgtccatcgg atcagttcct ggtgtcatat tcaatggatc cgttgtattt
    27361 tgaaagcctg tcgtgccacc tacgtccatt ggatctgttc cagtgccagt ttctaatcca
    27421 gtccccattg tgcttgctgg gctaacagta tcttgtgtat ccattgtatc ttctgttgtt
    27481 tctggctgac gatagccttt tactgtgatg acaaattttc catcagaaat atctcctcta
    27541 tattgatata aaggatcatt ttctggtgta gccgtctcag aatcataggt atcaaaagaa
    27601 aaagtatctt ttattttttc ccataaagaa cggtcttctt caccatccat ccgattttca
    27661 tctgtttcaa catctatacc agacaatccg tcaaatccta gtctagatgc tgcttcatca
    27721 gtagtataaa taacgatatc atctcgttca tacccttcgt tacgcaaccg ttcaattact
    27781 gataatgctt cttccctcgt actatagctt ccgatgaccg ttaaattttt ctcttccatg
    27841 taaattcctc ctagcaaata gatttatgat tggtatattg ttacttataa atttattcta
    27901 taggagacga ttgttttcta caaatattta gattggaatt tgattaaaac aatttaatt
//
LOCUS       DADQDV010000032        27524 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.032, whole genome shotgun sequence.
ACCESSION   DADQDV010000032 DADQDV010000000
VERSION     DADQDV010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 27524)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27524)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27524
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.032"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(45..1937)
                     /locus_tag="J8S10_001493"
     CDS             complement(45..1937)
                     /locus_tag="J8S10_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9630080.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(1934..3661)
                     /locus_tag="J8S10_001494"
     CDS             complement(1934..3661)
                     /locus_tag="J8S10_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9630081.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(3677..4327)
                     /locus_tag="J8S10_001495"
     CDS             complement(3677..4327)
                     /locus_tag="J8S10_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAZ9630082.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            4531..4827
                     /locus_tag="J8S10_001496"
     CDS             4531..4827
                     /locus_tag="J8S10_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAZ9630083.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            5019..5639
                     /locus_tag="J8S10_001497"
     CDS             5019..5639
                     /locus_tag="J8S10_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HAZ9630084.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(5731..6897)
                     /locus_tag="J8S10_001498"
     CDS             complement(5731..6897)
                     /locus_tag="J8S10_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAZ9630085.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(6909..7262)
                     /locus_tag="J8S10_001499"
     CDS             complement(6909..7262)
                     /locus_tag="J8S10_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HAZ9630086.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLKTVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            7390..8412
                     /locus_tag="J8S10_001500"
     CDS             7390..8412
                     /locus_tag="J8S10_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HAZ9630087.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            complement(8851..9285)
                     /locus_tag="J8S10_001501"
     CDS             complement(8851..9285)
                     /locus_tag="J8S10_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630088.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLMKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(9395..11254)
                     /locus_tag="J8S10_001502"
     CDS             complement(9395..11254)
                     /locus_tag="J8S10_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAZ9630089.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(11372..12532)
                     /locus_tag="J8S10_001503"
     CDS             complement(11372..12532)
                     /locus_tag="J8S10_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HAZ9630090.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            complement(12839..14263)
                     /gene="araA"
                     /locus_tag="J8S10_001504"
     CDS             complement(12839..14263)
                     /gene="araA"
                     /locus_tag="J8S10_001504"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HAZ9630091.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(14279..14977)
                     /locus_tag="J8S10_001505"
     CDS             complement(14279..14977)
                     /locus_tag="J8S10_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HAZ9630092.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(14934..16595)
                     /locus_tag="J8S10_001506"
     CDS             complement(14934..16595)
                     /locus_tag="J8S10_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HAZ9630093.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            16813..18213
                     /locus_tag="J8S10_001507"
     CDS             16813..18213
                     /locus_tag="J8S10_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HAZ9630094.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(18465..19544)
                     /locus_tag="J8S10_001508"
     CDS             complement(18465..19544)
                     /locus_tag="J8S10_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAZ9630095.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(19630..20589)
                     /locus_tag="J8S10_001509"
     CDS             complement(19630..20589)
                     /locus_tag="J8S10_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HAZ9630096.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(20601..22124)
                     /locus_tag="J8S10_001510"
     CDS             complement(20601..22124)
                     /locus_tag="J8S10_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HAZ9630097.1"
                     /translation="MDEEVKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHE
                     TADGDGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIE
                     PNSFGLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQ
                     KKPFGVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPR
                     LPSYPEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFD
                     RQIEEIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMED
                     TLLFGSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAK
                     GQVLKQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLL
                     DQGEHYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(22134..22697)
                     /locus_tag="J8S10_001511"
     CDS             complement(22134..22697)
                     /locus_tag="J8S10_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HAZ9630098.1"
                     /translation="MKIVETKLYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(22703..23566)
                     /locus_tag="J8S10_001512"
     CDS             complement(22703..23566)
                     /locus_tag="J8S10_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAZ9630099.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(23580..24476)
                     /locus_tag="J8S10_001513"
     CDS             complement(23580..24476)
                     /locus_tag="J8S10_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAZ9630100.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(24651..25922)
                     /locus_tag="J8S10_001514"
     CDS             complement(24651..25922)
                     /locus_tag="J8S10_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAZ9630101.1"
                     /translation="MKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTLTFWNGF
                     TASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFIALNYPD
                     FAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMYMYWNND
                     LFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLANGGKLV
                     NDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIEINGPWL
                     NNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFLKYWNTT
                     EIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQISAINNDI
                     INPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(25912..27429)
                     /locus_tag="J8S10_001515"
     CDS             complement(25912..27429)
                     /locus_tag="J8S10_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HAZ9630102.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
BASE COUNT         8031 a         5809 c         4748 g         8936 t
ORIGIN      
        1 acttttgtca cagcccctaa aaaaaataat aaatttgtac tattctatga agcttcttct
       61 tcagaaaact gactgttata aagatctgca tagaatccgt ctttttccat caatgtatcg
      121 tggtttcctg tttctacgat cgaaccatga ttcatcacaa taatgttgtc tgcatcgcgt
      181 attgtagaca agcggtgagc aacaacgaaa cttgtccggt tttccaatag gcggttcatc
      241 gctttttgaa tcagtatttc tgttcgtgta tctacactag atgttgcttc atcaaggatc
      301 aggacatctg gatttgctaa gaatgcccgc gcaattgtga ttagctgacg ctgcccttgc
      361 gaaatattgc ttgcatcctc gtttaataca gtgttatatc cttctggcaa tttacgaaca
      421 aaatcgtcta cgtgagcagc tttagcagcc tcaatgattt gttcgtctgt tgcatcgtcg
      481 ttcccatatt tgatattgtc atagatactt cctgtaaaca gccaagtatc ttgcagtacc
      541 attgaaaact gtgcgcgcaa ttcatcacgt gaaagatcac gggtatctac accatcgtaa
      601 cgaatactac ctccagaaac atcgtagaac cgttcaagaa ggttgatcag tgtcgtcttc
      661 cctgcaccag tcggacctac aatagcgacc atctcaccag gtttgacatc caagttaaaa
      721 tcagtcatta gcaagttatc tggtgtgtag ccgaattgaa cattttcaaa acgaactttg
      781 tatggtgtat ctttttcttc tggaaggcca gatttttcat tggacatctc ttcttcatcc
      841 aacacttcaa atacccgttc ggctgaagca actgttgatt ggatagtgtt catcaaactt
      901 gcaagttgag tgattggttg agagaactgt gttgtatatt gcaagaacgc ttgaacatcc
      961 cctaatgtca tgttcccatt tgcaactttt actccgccta gtacagcgac gaacacatag
     1021 cctagatttt taacgaaatt catcaacggc atgatgattg ccgaaataaa ttgagctttc
     1081 caaccagcgg catacagatt ctgattttct ttttcaaata cttcctggtc tttttcagta
     1141 tgattgaatg ttttaacaat ggtatgacca ccatatgttt cttctacttg gttattcaat
     1201 aaacctaaac ttttttgctg atctgcgaaa aacacttgtg atttcggcgc tacgatcatc
     1261 acgatgatca agcttaaagg gatcatcaat aacgcgacta acgtcaattg ccagctgatt
     1321 gaaagcatca tcacgatgac cccaatcaat gtgactgcac tagttacaaa ttgagtcaaa
     1381 ttttgctgca gcgtgcttgc gatgttatcc atatcattga ttgctcgaga catgatatcc
     1441 ccatttgtat gtgtatcata ataggaaatc ggtacacgat tcattttggc ttccaaatca
     1501 tgacgtaatt cataaactgt tcgttgggaa acacgtgtca taataaattg ctgtaaaaag
     1561 ttgaatacag cagaaatcaa atacatcacg attactgtcg caatgatctg cgcgatttta
     1621 tcaaagtcta tcggaaattt tgttacttgt tggccttgtt gcatctgttg agcgccagcc
     1681 attacacctt tgaatatttc tgtggttgct ttccccaaga cctttggtgt ttggatttgg
     1741 aagatcacgg ctgctattgc tagtacaaat acagcgatga tcgcaaccat acgtttagac
     1801 atatagccaa acaatcggcg taccgttccc cagaaatttt taggcttttc accttttaca
     1861 ccgagatttc tgccaggtcc accatgtcct ggaccgcctg ctggtccatg agagggacgt
     1921 gtgtttgttt tactcatgct aagtcctcct ctcttagttg tgaatgaacg atttcttgat
     1981 aagtttcgtt tgttgctaat agttcttcat gtgttccttt gccaaccagt tttccttcat
     2041 ctagcacaag gatcatatct gcatccatta ctgtacttac tcgttgagca actaaaacgg
     2101 tgatactttc tttcatattc gttttcaatg cttggcgaag attggcatcc gttttgaaat
     2161 ccaacgctga gaaggaatca tcaaacacat agatatctgc tgttttgact aatgcccgtg
     2221 caattgccag acgctgtctt tgtccaccag agaagtttcc tcctccttgt tccacatggc
     2281 tatctaagcc atcttccatc tctgaaacaa aatctttagc ttgtgcgatt tctaatgctt
     2341 tccaaatcat ttcatctgtt gcatccggct taccatactg catattgtct cggatcgttc
     2401 cagagaacag aactgctttt tgaggaacaa agcccattaa ttctcgcaaa ttatattgag
     2461 tcatgtcact aatgtccgtt ccatttattt ggatcgaacc agattcgatg tcatataatc
     2521 gagggatcaa attgactaag gtcgttttac ctgaaccagt cccccctatg attgcgacga
     2581 tctcgcccga cttggcttgg aaatcaatat cttccaatgc aagtttttct gctccatgat
     2641 atcgataatt gacatgattg aaggccaatg ttgcgttttt tccagcaaaa gaaactgttt
     2701 taggattttc agggtcatgg ataccgattt tttcatccaa cacttcatta atacggtcag
     2761 ctgaagcttg tgcacgaggc accatgataa aaatagcgga aagcatcata aagctgatca
     2821 agatctgcat cgcataagtc ataaatgcaa tcagattacc gacttccaaa gtcatatctg
     2881 ctatgtagtg tccaccaaac caagtgattg ctacgtttgt accgctcatg atcaatgtca
     2941 tcattggcat catcaatgcg acgatcgtat taactttgat tgccgtattt gtataatctt
     3001 tattcgctaa atcaaaacga ttttcttcaa agcgtgtctt atcgaatgct cgaatcactc
     3061 tgacccctgt caatccttct cgaaatacca ggtttaaacg gtcagttttc ttttgcatac
     3121 ttttgaataa tggaacagca aagtacatga ttccgccgat caaaataatc attactggga
     3181 tgacaactaa gaagattttt gtcaactgat gatctttttg ataagcaagt atgctcgcgc
     3241 caatcaacgt gattggtgca ttgatcatca tacgtaaaaa catttgtgta accatttgga
     3301 tttgagtcac atcattggtc gttcttgtga tcaaagaggc cgttccatat ttatcaaacg
     3361 catcttttgt cagactctct gattttttat agacatccgt acgcaattgc ttacccagtt
     3421 tctgtgattc acgagtagca aaaaatgtat ttgcgatagc agctaagata ctgatcaaag
     3481 aaaagccgat catcacaaaa cctgtatgcc aaatataatc gacatctcct tgcgctaccc
     3541 ctttatcaat aatattggag gtaagtgtcg gcaaatataa atctgccagt acttggatca
     3601 ccatgaaaac tgcagctgca attgctgaag tcaaggagat ccgttttacg atttttagca
     3661 tctagttccc ttctttctat ttatatactc cgtttttcag ccaagaaagt ttcaaattga
     3721 attcactgat tgcttgctct actgagtaat cttcagatgt tgaaaataag cgatacgaat
     3781 gcgcaattgt tgtaaataca gtattcatca ctaattggat cagtaattcc aattcatgat
     3841 cattttttac tttcagcttc gtccgatcga tcaattcaag caactctttt gcatcttgtt
     3901 tgtgttcttt atgtggatcg tgaggcgttt tttggcgact cgtatgagga gcgacttttc
     3961 ttgaggcacg gtaatccatg ttcataaaca agttacgata aaaagaagca ttctcgcctt
     4021 ccaaaatctc ataaatcatt ttagaaaaat aggattcgaa tcctttgaat agatcaccat
     4081 cggattcttt cattagttgt aacatatctt tagagctgtc acgtctcatt gtctcaaagt
     4141 aataaaaata aagatcctct ttatcttcaa aatactgata gaaactgcct ctagggatat
     4201 ccgctaattt gacgatatta gcaatcgaag cttcttttaa gggtactcta gaaaactcga
     4261 ttctcgcagc ctcgattagt cttttttgtt tttctttagg caaatggaaa aatgtctgtg
     4321 tcggcatatg gattctcctt tctttcaaga tgacacattg tcatatgacg ctatgtcatt
     4381 ataacacctc ctacctgttt tgcaagacat ttgcatagtt tttttcatta tcatccgata
     4441 cattaaaaaa gtgataagag gaatccttcc atttgaatta atgagagttg cccattaaaa
     4501 tagccacata ctaaacaaag gatgagataa atggcccaat caattagtgt ccaagacttc
     4561 aataaattgc ctctcgatgc tgacagcatc gttttagata caagaaatac cttagattac
     4621 acaaaaaacc acttaagcca ctcgctttct atccccgctg ctatcttgcc aagacaatta
     4681 aaaaatctag atccaaagaa actttattat attctaagct atacaggcag gcgatcagaa
     4741 gcattagccg atcaacttac tgctaatggt tttcgtgctg tttatatcat tggtgggatg
     4801 gaagctcttc agtcgagtgt tgcttgaata ttgcttgtta gattcaaaag aggctgtgac
     4861 aaaaaatcgt gtcacagcct cttttatacc ctgtcttttt ttagttattt attcttcaac
     4921 cttatcaata tgacttgata gccttttctt tttcgagtaa actgattttg ttagtcatag
     4981 ttataacaat catagcaata aaaggagaag gtaagcatat ggcatctgtt ttagtagtca
     5041 aaggtcatcc cctaactgca gaagaatcgc gcacagttaa ggcattgacg tcttttttaa
     5101 caagttataa agaaaatcat ccagatgatg aagtgactgt tttggaactt tatcgcgatg
     5161 atattccgga aatcgatgaa gaattattat caggttggga agcattacgt gctggtgcag
     5221 aattcacttc cttatcagaa agtcaacaac aaaaaattgc tcgtttcaat gaattgactg
     5281 atcagttcct tgctgctgat aaaatcgtta tcgcaaacgc cttatggaat ctaaatatcc
     5341 caacaaaatt aaaagcttgg ttcgataccg tcaatgtagc tggaaaaacg ttccgctata
     5401 cagaaaacgg gccagaagga ttagtgacag gtaaaaaagc actgcacatc caatctaatg
     5461 gcggtgtata caacggacaa gactttgcct ctcaatatgt aaaaggtatt ttaaactttg
     5521 taggcatcga tcaagtagat cagctattca tcgaaggaat cgattatgac cctgaccgtg
     5581 cagatgagtt gatgcaaaat gcattagata aagctgctgc tttaggtaaa tcattttaaa
     5641 aattgagata aatgcataca aaagagacag aggaaaaaat cttcaaagca gcatttgtgc
     5701 cttggatatt ttcccatctg tctctttttg ttattctttc tgctttttca acggattttc
     5761 ttcataaaga gaagagattg ttgtgtacca ttcaaaaaca tgagtaatca ctactttagc
     5821 tgctgcataa acaggaatcc ccaagatcac accgatgatt ccgaacaatt tcccagaagt
     5881 cagcagaact aataaaatcg ttactggatg gattgctaac tgattcccta gtactaatgg
     5941 agagatcaag cgtccttcta ttgtctgctc tactgcaaaa acgatcagta ctttgatgat
     6001 catgaatgga cctgctacaa tggctaaaaa gatagccgga atcatcgcta aaaatgatcc
     6061 taagtaaggg atcaggttta aaaaacccgc aataatcccc aacgtgacag catactctaa
     6121 accaatgacc gcaaaaccaa tcataaacat gattgccaca gcaaaagcca cagttagttg
     6181 tcctcttata taagaagaaa cttgactatt catttcactc agcacattca acgtcggttt
     6241 ttgcatgcgt gtcggtaaaa atttgacaaa ataaggtgct aattgtttac cgtctttcaa
     6301 tagataaaat aagataaacg gcatcgtcag cagagccact aaaatagtcg ctaccgcgcc
     6361 gacaaaactt ccaagactct gaactgtact cttagatata tcttggatca tatcgcctgc
     6421 cgaattcatg aacttatcac ctgctgtttc caactgttcg cgaaattggt tgaacagcgg
     6481 gtcccgcaaa atctcggtta atttattatc aatcgtatct acatattgag ggaagttact
     6541 gatgaagctc actgtttgtt cctgaatctt agggatgatc actacgctcc cccatgcgat
     6601 tagtgcaaca accaaaacaa acagcccaat gatactgtaa agccttggta cttttcgctt
     6661 ttcaaagtaa tcaactaccg gattcatcaa gtaatacaag attcctgcta aaatgatagg
     6721 cagacctacg attgctaaaa attgccagat tggtgcaaac aaatatgaaa cttttgtaaa
     6781 taaaaagacg atcagcaata ttaacaatac aacaagtaag gctgtgacta cttgattatt
     6841 taaaaaccag cgccaaaacc acgataccgg tctgttcttc ttattttttc cttccataat
     6901 tcctcctgtt agttataaaa aatttggctt cccaaaccaa tagcaggcag tctatgcgga
     6961 tgaagataga ttccatttgc aatttgtcct tcttctggac aagcatcaaa aatcaatgat
     7021 acgtgagcta ctgtctttaa attcccattg gccatcggac cgacataatc gatcgtatat
     7081 acctgatcat caaaagcaat tgttccgcct gctttcaaag aaaaaggttc gtcttttgat
     7141 acttcttgaa tcaccgaata ttttcgtaag gcagctgttg ctgttttatc gaacaaaatc
     7201 agcatgggtt cttccttgtt tattgcttct gtcccaattt ctgtaatctt tgcctgaatc
     7261 attgcactct ctcctttaat tgctttcaaa aacagtataa cacattctca ttctttagcc
     7321 gtgtggaata attatgtgat agaataaaaa cgaaaactat ttcattacaa ttaggaggaa
     7381 tcagctcata tgatcgaaaa gataatttta ggaacctata cgcgtcgcga aagtaaagga
     7441 atctatacga tcgaccttga tacagaaaaa gaagaattag ccaacctttc attagctgtt
     7501 gaagaaaata gccctaccta tgtagcaaaa agtaaagctg gcaatcttta cacagttact
     7561 agtgtggatg gattaggtgg tgccggtgcg tacgataagg attttcattt tttgaatgcg
     7621 gtaacagagt ctggcgctcc tttgtgttat gtagcggttg atgaagcacg tcaattacta
     7681 tacggggcga actatcataa aggtgaagta aatgtctacc atatattagg agatggcgaa
     7741 ctgaaagcag cagattcaat attccatcaa gaagcgacag gtcctcataa aaaccaagat
     7801 catgcgcatg tccactatac ggatctgact cctgaccaac gattagtcgt atgtgatctt
     7861 ggtacagatc gtgtgtatac ttatgatgtg tccgaaaacg gcaaattgaa tcttgtaact
     7921 accttcactg cagagccagg aacaggccct cgccatcttg tctttcatcc aaatggacaa
     7981 ttcgcttatt tatttggtga attagacagc acagtccgcg tgctttctta taataaagaa
     8041 acaggtgctt ttgaagaatt acagaaaata tcgaccttgc cagaagaatt cgacggtgaa
     8101 aatggagggg cagctatccg catttcaaat gatggcaagt tcctttatgc ttctaaccga
     8161 ggacataact cgattgctgt attcgcagtt tttgaagatg gttcccacat tcaaaacaag
     8221 caaatcatct caacagaagg ggattttccc cgcgatttcg cactagatcc aagcaataat
     8281 tttgtcgtgt gtgccaatca gaacaccgat aatctgacat tatatcgccg tcatcctgaa
     8341 acaggattac tggaattact gaaaaaagat gtctatgtac cagaatgtgt ctgtgtttat
     8401 tttgatcgtt agtaagaaaa ggagaatgaa atgaatcagc aagacgtatt agacagacta
     8461 cgggaagaac taaatattcc tttctttgat gggaaaatcg aagataaaga gtatagcgaa
     8521 gaggaatatc agaaactcaa agccgattta cagaactact ttgaacaata tgtacagaat
     8581 gtagaaaact aatcagcttt ccatactatc tgaaaagaac atcaggacaa gacttttccg
     8641 tctatcctga tgttcttttc tacaaataaa aaaccgccga gatggttaga ctcgacggaa
     8701 aaggagtatt tactcgattt tgagtaagta caaggttgtt gttggttata ggtatgtcat
     8761 tatcataaag gattttgatc actctatcat aaaggtaata ttacatttat attagataac
     8821 tctagttttt attgttatca aagatttctt ttattttttc aacaacaaat tagtcatttt
     8881 ttggatggca gctgtcaatt ggtctgtcgc ttggtcttgt tttgcttcag atgtattgaa
     8941 tagatcttca tctacccctg attcaagatc gatactttgg atcatttctt cacagcctgc
     9001 tacatatgaa agataagctt tttcaaaatt tttatgaatg cccattgctt ttgctggtgg
     9061 acgcaaagta ctgactttca taagcattgc ccgatatttt tttgttcctt cttcaaataa
     9121 caggatgatc tcttcaagag tcgatttgtc cagttcactt gtttttcctt catcaattgc
     9181 gtttctgatc acttcatatt tcggatgcat tccttctccg attgcttctg tttccttgac
     9241 gatttgatcg atggactgca cataatagcc aatattcggt aacatgttcg ttttcctact
     9301 ttctccattg ttgttattat ttattctact tgtttttatc ctcaaatgac aagtacttga
     9361 aaaaatttaa tggtttctat acagctcgcc attcttattc gtgctcaaag aaaccatctg
     9421 ctaaactata ttgtttccct gcgacaatgt catattggat caattgatat tcgtcgtaaa
     9481 tctcttgttg cgagcgattg aattgcgctt ctttatacca ctgtccgttt tgatagtaca
     9541 gttctcgttc aaacgccgga agttcctgtt ctaatgataa aagcagctga taaaagccat
     9601 ttgttgtctg attcgtctgt tccattagat tcgctgcaaa ataaaacgga ctggtgattg
     9661 catcgtgagt cgtttgcttt tctaattctc ctttactgtc gaacataaga aattgtgttt
     9721 catgcaatgt ttgtttgtca ttttttgctt ggatcgtatc tgaatagatc cctggaagat
     9781 gatcccccca aaaaacaact aaagtccttc tagaaagatt cttcaattct tccgtgaact
     9841 gcttcagtgc cgtgctgcta taggaaatat cttgcagata attctctaag tcaagtgtcc
     9901 cacttccatc tgaagttttt gcaggatagt ctagattatc atactttcca tcgtagggca
     9961 tatgtgtctg catcgtgact aaatgaatga actgaggtgt tttttcttcc ttgagaagtg
    10021 tcattacttc tttgtaagct gactcatcag aaatatatgg attattctct atcgtatccg
    10081 tataggtcat cgtacgctcg ctgatgaact ggtcaaatcc taatgtctga taaacatcct
    10141 ctcttttata catcgaagta ttgtatggat ggatcgctgt cgtctggtat gattgtgcgt
    10201 ttaacgctga aacgatagaa ggaagctgat ccatttttgg tacaagcatc gtgtaagggg
    10261 tggtgagttg cgcattaaat aacgccatag aaaaaccagt caatgcttca aattcgatat
    10321 ttgctgttcc accgccatag ttttgagaaa gcatattgcc actatatgtt tgatcagcta
    10381 cttcataata atctgccaat ggctcaccag atacttctac gccgtttaat cgactaggat
    10441 ctgagaaact ttcactcatc acgaacacga tgttcggcga ctcttcctct acagttttat
    10501 ttttttcatc ggctagcttc tggtattttt cagtgatttc tttgatcttt tctttcgaat
    10561 atccttcagg ttcatccatt ggttctacct tcagattgta caaaaaccca ccgataaaac
    10621 cagtgttata gtagttcatt ttctggctgt aaggtatcca tagtgccgtt ttattatatg
    10681 cttttcgcaa caaattatcg ggattgttga aattactgat ataccctagc agtccaattg
    10741 ccacaagcag tgtcgttaat cggatcaatt ggaatcgcct tccttttttc aggcttcgaa
    10801 acatgtacca gcaaaacaat cctatcacgg ttcctgcggc agctaagatc actgtaaaca
    10861 gcatagtgcc ggtcatatct ttcagcaatc cgatttcagt gatcatcttc aaatcgtctg
    10921 gataaatcgg ttcttgccga taactcattt tcatataatt tgcaaaacct aatacaccga
    10981 tggctacgac atacgtaagg gaacctaaag ggacagatcc tgctagtgca atcagaaaaa
    11041 taagaataat cagcaagacg agacaggcta agaagaattt ttccgtatgc caagaaaaag
    11101 caaatttcaa cgcaaggtct acggatagat cattttgaca ccactgcaaa aataaattac
    11161 taaaaacaac aagaaaaaag atactgatga ttgctgctgt tccttttaaa atctttttct
    11221 gtttggtcga aagtctgctt atatatcttt tcaaatgctt gctccttcat ttctatcaat
    11281 aaaagaatgt tgcttctctt attttagttg tacgaaattc gaaagtaaag aacggaaaga
    11341 agaattaatg aaatccaaat attctctttc tttatggcct ttctggtttc tttaataagc
    11401 ggacctttcg tactccagaa attttttcta gctgttgttt cacttgattg agctgttcaa
    11461 aatcagtact gtctatgtca atcaatatgt agacatgctc attcttatgg ttacgcgata
    11521 tatctgcgat cgctagctcg ttctcattca gcagagaaaa tatctctgct aatatattgg
    11581 ttttcttttg ataaaatata gtgaatcgaa acggcgcttg gaaaaacatt cgtgcggatg
    11641 gataattgac cgcttctcta accgtaccga acaaaagata atcttttaag gcttcaactg
    11701 ccaaacgtcc gctgtctgcc aaagcttcct gagtcgatcc ccctagatga ggcaacataa
    11761 gtatacggtc attttctaag aactcttctt ctggaaaatc agtcaagtat ttagccagat
    11821 gttgtttttc caatgcttgc ataacagcat atttatcaac aatttcactt cttcctacat
    11881 tgataagtac agcatctttt ttcatttttt ctatattcgc ctgatcgatc aatccttttg
    11941 tatcttctgt caacggcagc atgactacga tgtaatccga ggtagaaaga actgtttcta
    12001 aatctgcttg ccgaacataa tccaactggg catcgcggat agaataaccc aagacatcca
    12061 tccctaagct atagcaactt agcgctactt ttgtgcctat cgctccaaga ccaagaagac
    12121 cgatggtttt gccttgcaat tctcgtccca cataagcact tcttttgttt tctgcctgtt
    12181 ctaaaatatt aggacctgtt agtgtttgta ccatacgact tgcttcgatt atcggacggg
    12241 aagataagag caaacagcac aaaacaagct cttttactgc attagcattt acacctggtg
    12301 tattcatgac gatcgtcccg ttttcagaag ctttttcaac gttgatcgtg ttcaccccaa
    12361 caccagctct tgaaattgct agcaaatctg gtgtaagcca ttcatctttc actttcgtac
    12421 tacgaataac tattccttcg gctggcaaat catctattat tttgaaatat tccccttgta
    12481 acttttctat ctcttgttct ggaatagcat caatcaaatg aacgtgatac ataaaacccc
    12541 ctccttacta acaagtatct cgaaatttct gcaattagac aactgtttac catttgactt
    12601 cctagaagca aaaagagcag ttagagcaga gtaggctgag tgataaaaat aaggctatga
    12661 caagttactg ccataagcct tattttcgag agcaaaatat tgagggtgag atatcttgat
    12721 aaatggtgtt ccgttagctg acattgataa taagactaaa tttcaaaaaa gttgaaaagc
    12781 aaatttcgtc aatctcttct tatttcttaa aactaagtgg ctttttcaca acctcttttt
    12841 atctaataac cactgtttcc aactcaacta attttgccca cgtttcaatt tgatctgttg
    12901 ttagatttag cgagacaacg gtatgatgac cgccacctgc ctgaatccat gaatggacac
    12961 cttcatggaa attcggttta gttttccata acacacgtgc aacaggtaaa ttaggtgctt
    13021 cagtcgttgg ttcaaaggct tctacttcat tgatcagcag tttataatgc gtaccgaaat
    13081 ctgccatcga tacgactacc ccttctcctg ctttcccatc aaatacaaga cgcgccggat
    13141 cttctctatc tcccattgat aaaggagaaa caacgattct tggtttcgtc gcagcaagcg
    13201 tcggatctac ttccatcata tgggattcca agattgcttc ttggccacta gctagctcgt
    13261 aagtataatc ttccatgaat cctgtatctt tccctcgagc catgattttc agcaaccgat
    13321 caatcgctgc agttttccag tcgccttccc cagcaaaacc gtatccttct gccatcaaac
    13381 gttgtacagc tagtccaggt agttgtttca ttccatacag gtcttcaaaa ttagtcgtaa
    13441 aagcgttata gcctccttct tctaagaaac ggcgaatacc gatttcctgc tgagcttgta
    13501 cttttacatg ttcctcccat gtcttttctt cataatcacc atagtcgaag gtatacaatt
    13561 ccttgtactc ttcaaataat tgatcgactt cttcgtctga tacgcgatcg attacttgta
    13621 caagatctcc gataccaaaa taatcaacag tccaaccaaa ttgaatctgt gcttccactt
    13681 tgtctccttc tgtgacaccc acgtttctca tgttgtcacc aaaacgagcc acttttattc
    13741 caaaactttc attataggct actgcaacat ccatccaatc agcaatctct ttttggatct
    13801 caggtcgttt ccagtagcca acgacgattt tattttgttt atttaatcga gcattgatga
    13861 acccatattc gcggtcacca tgagcggatt gatttaaatt catgaaatcc atatcgatcg
    13921 ttttccaagg aatgctttcg ttatattgcg tagctaaatg aagcaatggt ttttgtagaa
    13981 gctttgtccc gcggatccac atttttgctg gtgagaaagt atgcatccaa gtgatcacac
    14041 ctgctacttc ttctcgataa ttgacctctt tcatgatttt tgtgatcgta tcagcagtaa
    14101 ctgctaattc ttgaaggcgg attggataag gcaattggcc attttcattc agttcatcga
    14161 ccatttcttg tgcatgtttc tttacttctc gcagtgcttc ttccccatat aaatgctgtg
    14221 atcctacaac aaaccaaaat tctttttctc caatattcaa cataattagc cactcctttt
    14281 atttgttttg tccgtaatac gcattttttc cgtgttttcg taaataatgt ttatctaaaa
    14341 tccgttgagg cagctcttct gaaaatgaat tgagctgtct ggtaaataaa ttcatcttgc
    14401 atacttcatc tagtacgact gcgttcatta ccgcactttg cgcatctttc ccccaagtaa
    14461 atggaccgtg tccgtgtaaa agtacccctg gaattgctaa gggatcaatt ttgcgttctt
    14521 tgaatgtttc tatgataact tttcctgttt catattcgta cccgctgtcg atttcctgtt
    14581 gtgtcaaaaa tcgagcacaa ggtaccgatc cataaaaagt atctgcatgc gtcgtcccca
    14641 tcgcaggaac atccaatcct gcttgtgccc agatcgtcgc ccatgtcgag tgagtatgga
    14701 cgattcctcc gatttgagga aatgaacgat ataaaacagc atgagtaggc gtatccgaag
    14761 agggattgag tttaccttca atgatatgat tgtccaagtc cacaacgacc atgtcgtctg
    14821 ctgtcatctc ttcataactg actccgctag gtttgataac gaaatatcgt gtttcaggat
    14881 caaaagcgct cacatttccc catgtatatt tgacgagtcc gtgtttaggc aagtcaagat
    14941 ttgcttggta tacttcttct ttcagttgtt ccagcatttt ctatcactcc tttttcttgc
    15001 aattgatgaa tcgctgtttt ttcaatgtcg atcccctcac ggtaacgtct cataaatatc
    15061 tgatagcctg ctatttcttc tgctgaaggt gtgatggtga ttccttggtc ttgtccaaac
    15121 acgtcttctg ccaagaagtt ttctaaagac ttcccatgtc gatccatcat ataggctgct
    15181 aataacgcga ttccccacgc tccaccttct ccggctgtgt ccatcactgt aactggtgcc
    15241 tccatagcag atgctagaat ccgctgtcca acttctggtg ttttaaaaat ccccccatgc
    15301 cccactaaac gatcaatttg gacattctca gatttcaata tatccattcc gattctcatt
    15361 gcaccaaaag cactggctaa atggatccgc atgaaattcg ctaaatcaaa acggctacct
    15421 ggtgtacgta caaataatgg ccttccttca tttactcctg taatgttttc accggaaaaa
    15481 taaccataag aaagtaatcc cccgcaatcc gtatcgcctt ctagcgcttt gttgaataat
    15541 accgtgaata atttatctct gcttatctcc atacccaaag aattggtaaa ttcttcaaaa
    15601 atactgaccc aagcattgat atccgaagag cagttattcg tatgaaccat gcctactagt
    15661 tctcctgaag gtgtagtgac catgtcgatt tccggatgga cattttctag ttctttttct
    15721 aatacgatca tagcgaaggc ggaagtacca gccgaaatgt tccctgtccc tttggctaca
    15781 ctgttcgtag cgaccatacc ggttcctgca tccccttctg gcggacaaac cgggattcct
    15841 ggtctcaaat ttcccgtagg gtcgatcaga taagcccctg attcgcttaa cttgccagct
    15901 tcttctcctg ctactagaac tttaggcaaa atgtgatcca agtcaatcgc tacgtgcgct
    15961 ttttcgatta actgaccaaa aatatttttc atttcttgat ggtaggtttt cgttgaagga
    16021 tcgataggaa acatgcctga tgcatctcct acgcctagta ctttctcacc agtaagctgc
    16081 caatggacat aacctgcaag cgttgtcaaa aaattaattt ctttcacatg ttcttcttta
    16141 ttcaaaatag attgatacaa atgagcgata ctccatctct gcggaatatt gtattgaaat
    16201 ttttccgtta atattcgttc tgcttcttca gtgattgtat ttcgccaagt acgaaatggt
    16261 actagtaact gttccttgct atcaaatgct agataaccgt gcatcattgc actgaaccca
    16321 atcgacccga ttgtcgtaag attctcgcca tagatttcga atacttctgc tgccattttt
    16381 cggtaactga cgcgcagtcc tttccaaata tcttctaatg aataggtcca gataccattt
    16441 tctagtttgt tttcccactc ataactacca gcggcaatag gagtaaaaga tgaatcaatc
    16501 aatacagctt tgatcctagt tgatccaaac tcaatcccta aagatgtacg accatctatg
    16561 acatctaaca tactttgcgc atttacttcc ttcataatga tttaactccc tccttctcgt
    16621 caaacctgat caaaccgtct ttttagtagc gcttacaatg attattgtat acttttgtac
    16681 gtacatgtca agcagttatt tacaagaata caataaaaaa cacttgtttt gtacgtacat
    16741 aagttataaa atgaaattgc ttacaaaatc tgatcaaccg ccttctcgaa attctagaag
    16801 gagagaatac ttatgaaaaa agaaaaaaaa gtttcctcat cgtttattta tttttttggc
    16861 gcatttggcg gcattctatt tggatatgat attggtgtta tgaccggcgc cttacctttt
    16921 ttacagcatg attggggttt ggcaggtaaa gcttctttga taggatggat cacgtcttcg
    16981 gtcatgttag gtgcgatcct tggcggctct ttatctggtc ttctttctga taagcttgga
    17041 cgacgaaaaa tgattcttct ttctgcactt atttttatgg ctggttctgt cctttctgca
    17101 tctgcccctc acaatggttc ttattttctg attgcagcaa ggattcttct aggtttagct
    17161 gttggcgctg catctgccct agttcctgct tatatgtctg aaatggctcc tgctagacta
    17221 aggggaagat tgtcagggat caatcaagtg atgattgctt ctggcatgct cctttcctat
    17281 gttgcagatt atttgctaaa agggttgcct gaaacgatgg cttggcgcgt gatgttaggg
    17341 ctcgctgctg tccccgcgct gattttattt ttcggtgttt tagctctacc agagtcaccg
    17401 cgttttctta tgcaatctgg ccgcttggaa gaggcaaaaa gagtattgaa ctatattcgg
    17461 acaccaaaag aagctgaaca ggaattcgaa caaatccagc tgaatgtcaa acaagaaaag
    17521 acaaccggaa cttcttggca tactttgttt ttagaaaaat atcgttcctt agtcattgcc
    17581 ggtattggtg tagcagtatt ccagcaattt caaggagcta atgctatttt ttactatatt
    17641 ccgctgatcg tagaaaaagc gactgggcat gcagcgagcg atgcattgat gtggccgatc
    17701 atccaaggaa tcattttagt tgctggttct ttgctctttt tggttattgc agacaagttc
    17761 aatcggcgaa ctttattgaa aataggcggt agcgtgatgg gactttcttt catcctacca
    17821 gctgttttag gaactgtact ggatgctcat acaaattcgt tgttgattct cttgttttta
    17881 tgtatttatg tcgcatttta ttcttgcaca tgggctccac tgacatgggt aatcgtaggc
    17941 gaaatattcc cactagctgt ccgcgggcga gcatctggcc tagcctcttc ttttaattgg
    18001 attggttctt tcctagttgg cttgcttttt cctgtgatga ctgcttctat gtctcaagaa
    18061 atcgttttcg gcatttttgg gatcatctgc tttttagggg ttttatttat tcaagagatc
    18121 gtaccagaaa ctcgtgggaa atctttagag gaaatcgaac aaagtgcatc taaaaaaact
    18181 tatcctaaac gtatttctat ccatcattct taaagaggtt gtgacagaag tggtcagctt
    18241 caagaaataa gaaggaaccg cttagtttcc agtcacaagg aacaatttca aaaaacagct
    18301 tctcatgttt gatgaatatt gtgacttgtg accagttggt aggagaacac cgtttagtgg
    18361 agaggtggtg aaagaaacgt tcagccttga gcgatgacaa aagctctcac aaacattgcg
    18421 acgagtaacc gtaggagcaa taagaggcgg taaaaacccg tctcttattt ttcgttttct
    18481 ttcactgttt cccgttcaac tagtacaggt tcatagagaa tatttggctg tgcctgtcct
    18541 ttttcaatcg ttgtgacgat ccaccgtgcg gcatcttgtc ccaacttttc ttttggatgc
    18601 gtcaatgttg tcaatttttt attccctaaa tggcttaaag aagaatcgtc tgttcctacg
    18661 atcgataggt catctggaat atgatagcca ttttctgtca acttatctag cattaaacta
    18721 gctatttgat cgttatagca aatgatgcca tctaaagctt gttcttcttt caaccgttgt
    18781 actgtttttt cagcgattgt ttctcgtgtt tccgtggtga aagtaatgat atcttccgtc
    18841 aaaaaacgca cattatactg ttcacacgcg ctgataaaac ctttcatcct gtattttcct
    18901 tgaagatcgt cgatttttgt gatgaacaac agacgctgat gtcctttttt tatcaaatat
    18961 tctgctgcca taaaaccgac tttcacatca tctaaacaaa tataagaggc atttaactct
    19021 tcataagcag cattgatcat caccatcgga atgccttgtt ctctcaaagc aacataaagt
    19081 gctaagtttg ggttatactg attacttttc gtaggctcaa cgatcaaacc atctacccca
    19141 taagcaatca ttttcttcaa acactctttc tccaattcgt gatcgttatt cgtactggct
    19201 aaaagcaatg aatacccaga ttctcgtaat tcattttcga ttcctcggat aatcgacgga
    19261 aaaatataat cagagagata tgtggtgatg acaccgatcg tttttgttct gttcaatggt
    19321 gttttttctt tcttatagct gtcatctaca tatgtgcccg accctttttc tttacgcaga
    19381 tagccctcat ttaccaacac agcgattgct tgccgaatcg tatgtctgct gacgtcatat
    19441 atttcttgca gcttgaattc tgagggaatg gttgtattta cttcgtattc ctcacgaagg
    19501 atcttttgtt ttatctcttc tgcaatatct tgatattttg ccatttgcct tgcccctttt
    19561 tatttgtacg tacatatatc ataacgagtc tgcaaggttt attcaagcaa aaatcaaggt
    19621 ttcttgtgct cataaggcat acggaacagg ttcaccaaat tctggaaatc cttgctcatt
    19681 ccacgtaaag cattgcgcgt tcgcgtgccg attaggattg tctaacggat cccctttttg
    19741 gttcttctct ggtcgagcat gatagatcaa aatatcaaag cacccgtctt ctgaaaccgt
    19801 aaacgagttg tgaccaggac caaattgctt atttttttca gaagaaacga atactggctc
    19861 cgataattta tgccatgatt cttttaataa aagattcttg tgctcatcag cccacagcag
    19921 gcccatggca tagttttcat ctgttgcact accagaatac gtaatgaata ttttcccatt
    19981 gcgagtaagg actgctggac cttcatttac tgaaaaaccc cgtttttccc attcatactc
    20041 aggtatagaa aggaggatct gcttcccctt taacgtccaa ggattatcca tttcggatag
    20101 ataaagatta gaattcccag taatttcagg atcttgttgg gcccacacat aatatagctt
    20161 tccttgagaa gagaaagttg ttccgtctaa actgaaagtt tcccttttcg tttttatttg
    20221 tcccttttct atccaatctg tattcattgg atctatatgc tgattttcaa gtacgaacat
    20281 gcggtgatga tgagattcat cacgtatagt tttatgattg cttgcagcaa agtaaatata
    20341 ccattttcca ttgatataat ggacttcagg tgcccagatc aattcactca tcggtccttc
    20401 ttcatgagcc tgccatacaa tcaggcttgc agcatgttct aattcattca gtgactttgc
    20461 ccttcttaat tcaatcactt ggtagcctgg aaccgatcct gtaaaataat aataaccatc
    20521 tgtatgttta tatacccaag gatctgcccg ttgccgaacg ataggattat tataaagtgt
    20581 cttcatcata acaaatttcc tcacattttc tttattctaa ttacattcca agagtatttt
    20641 tctatcccta catttaattc gtcatgtttt tctattgaaa aatagtttat ttcaggtttt
    20701 attttttctg gttcttcacg tgtatttttg tccaacagat cgctactggt taatgtgtag
    20761 tgctctcctt gatctagcaa attgaaatca tgttcaatcg ttatcttttg ttgttcattt
    20821 gtgcgattga tcaagaaaat agtcagctga ttgccgttat ctacgatcac actgtccaca
    20881 taaggaacat tttttatctt ttcacaatca taaacagggc aaatgatttg ttgtttcaat
    20941 acttgacctt tagcatattt cgataagtgt tgcatcacat aataagttgg attcctccat
    21001 gcttgtcctt tagcatctgt cagtattaaa ggtattgtgt ttactaacaa tgattgacaa
    21061 ctaatcttta cgcgatctgc gtgtcgtaaa atagccagcc ctaatgaacc aaataataat
    21121 gtatcttcca tagtaaagta acaccaatcg atgggactac cgacttcaaa atccctatgt
    21181 cttttttccg gttgggcatg tacattccat tcatcaaacg ctagatacat tgttttctca
    21241 cttctcaaat atccttttac ataatcacaa gtagcaacga tttcttcaat ttgacgatcg
    21301 aatcgataag cttttgcaag gtatgtcgct gtatcatcac gctcattttt aggaggttta
    21361 gtcaagtctt cttcatcata cttatcaata tagttatgca aagctaaata atctacattc
    21421 tcataagctt cttctaatgc gatacgatcc cattcagggt acgatggtaa acgtggcgta
    21481 gagcttccaa ctaagattgt ttcaattgaa tcatccacta acttcatgac ttttgaggct
    21541 tcatttgcta acctaccata ttcataagca ctcttagccc ccacttgcca tggaccgtct
    21601 agctcattcc ctaaacacca taatttaacg ccaaaaggct ttttttgccc attttttatt
    21661 cttaaatcac tccagaaggt tccttttgga aaattacaat attctactaa attttttgct
    21721 tcatcaattc cttttgttcc taaattcacc gtgaatatcg gtttcgcttg tacatgactg
    21781 atccatttaa aaaattcgtg gagtccaaaa gaatttggtt ctatacctcg ccatgctaaa
    21841 tcaatttttt ttggtcgttg ttctttccta cctacagtat ccacccaatc ataaccagat
    21901 gtaaagtttc ctccaggata gcgaatgaca cctaattcta attcctttac ataagagagg
    21961 acatcttgtc taaacccgtc accatcagct gtttcatggc ccggttcata aatccctgta
    22021 tagacgacac ttcccatatg ctcaacaaat gagccaaaca gccgagaact gatctctcct
    22081 accgtaaaat cctctctgat ttttactttc acttcttcgt ccaacagctt tccctacctt
    22141 tcatttccta tagtcaagat aatagataca agtttccata cgccaccagc aaagataaaa
    22201 ataaaaggag ggaaaagaaa tatgagcagt acaaatccta ataacaatac gcaacaaaga
    22261 atatttctca aaaaatcaaa aaatactttc catgcacttt gttcaaaaat ttgtaaaaat
    22321 gtgatatctt tgttttcaga aatcacatat atccaggata aaagaaacat ggaataaata
    22381 agtaaaacta catatccact aattgaaagt acgattgtct gttcttctaa taattgatta
    22441 acaagaaaat aaataatgat cgttaacaga ctaaggaaca agttcttacc aaaatgttgc
    22501 tttattcctt gaaagaaaaa ataaatgata tttcctgatc cctcaccttt ccattgcgcc
    22561 attacataaa aaacagcaca tgtagcaggc acgatagtaa taacaggcaa acacacgatt
    22621 acccagagaa tacctaataa gatgtaatca gaaaccacaa tcaactgtcc ataaagttta
    22681 gtctcaacta ttttcatctt cctcactctt tcattccaga catagctgtt ccttgaacaa
    22741 aatatttctg tgcaaaaata taaaccacta gtaatggcag cattgaaata accgttccag
    22801 ccattacagg tccataaaaa gaaatgttct gccctgtaaa taaagctaac cctgctggta
    22861 aagttctcat ttttgaacta cttgtcaata tcaatggata aagcaagtca ttccaactat
    22921 tcatcagcgt gaaaatccct aatgataaaa gagtaggttt gctcaatggc aacatgattt
    22981 tcaaaaaaat attaaactca cttaatccat caatgcgtgc tgcctcttcc aaagaatctg
    23041 gtaaagtaat aaaaaaggaa cgcatcatga agataccaaa tgcagttgtc atacgaggaa
    23101 tgatcaaacc tgcataagta tcaagcatgc caagcaaatt gacttcaata aatagaggaa
    23161 tcatgaagac ttggaatggg atcatcattg tcagcaaaac gaaatagaac aaaactgatt
    23221 ttcctttgaa acgcatacga gcaaatgcat accccgcaag agaatcaaag aatacagaag
    23281 tgatcactgt ccctccagca aaaatcactg tatttttgat gtaatctaat aaagggatcg
    23341 ttgtccaaac cttaatatag ttatctaggg tatagctatc tgcaaatatt ctaggcggaa
    23401 atgagataat gtctttttcg tgtttaaaag aagaaataat cagccacaaa aaaggaaacg
    23461 caataaccaa caatataact agcatactaa tcgttcgaat gattttttta ccactaactg
    23521 cttttcgact attcacagta actgtaatcg agctttctgg tgccatacag gtttccctcc
    23581 tatttcattt gtttttcttt ccgtgacatg tacacattag tggagatagc tatagttgca
    23641 acaatgataa acaaaaccga agacagtgct gatgcatagc ccaattcata aggtgctgta
    23701 aatcctcgac tgtaaatata ttgaacagct gtttctgtct taaattgtgg gccaccagcg
    23761 gttgcaacat atacttggtc aaacacttgc atcgaaccaa tcagattcgt taaaatacaa
    23821 aaacctaagg agggaacgat ctgaggtagc gtaatgttaa aaaactgctg tcgatttgtt
    23881 gcaccatcca tttgagcaga ttcatacaaa gagggagaga ttccctgaat agcagtcaag
    23941 agaatcgtca tagtaacacc aaaattcttc caaacagtca tgatggctac cgtcggcata
    24001 gcaagggttg gatcgcgaaa aaattgaggg atcggcaagc cgacttgtga aaacaagtaa
    24061 ggaatcgccc ctacattcgg atcaagcaac atagaaaaaa taatcgcaat tgacgtcaat
    24121 gaacaaataa ctggaatgta aaatgtcgaa cgacaaaaac gattgaatct ggtattttta
    24181 gataatgcta ctgctgctaa taaaccaacg ataatttgtg ttggcgtttc gagtacggtg
    24241 aaatataaag aatgaatcaa cgaattaact gctcgttcat cactaaatat acgtgtgaaa
    24301 ttttcaaaac ttacaaaatt tcttgatgta aagaaaatat tcaaatctgt aaaactaata
    24361 gcaaatgttc ctaaaagcgg tatgacagta aataataata aaactaaaaa agatggagtt
    24421 aaaaacaaat acgcagcacg atcaggacga ttccaatatt tggtgaatcc gttcatatag
    24481 tccacctcat ctttcatttt gataaaatat acaatcttgg tttaaacgaa tctgaataag
    24541 atatccgaac aatcgctgtg atttttgcaa taacacctat ctgcaaatac taggtcgatc
    24601 attcagatat ctgtatcttg ccaacagtct atcctgtata aagttctgta ctatttttgc
    24661 agtaattgat tgatggcatc atctgcatcg ttcatgagtg tctcaggatc ttctcctgct
    24721 aataattttt caatcagtgg attgatgata tcgttattga tcgcagagat ttgggtaaaa
    24781 cctggtaaat atggctctgc atagtccatt tgtttcgata attcagatac aataggatca
    24841 ttttttactt cttcatcttt tgctactgaa tccaagtagg caggaaaacc attttcgata
    24901 ctccattttt taccaatttc agttgtattc caatatttca aaaactcata gacagcttct
    24961 tttttattat tatctgtact tgccggaatg gcatatccta cgccatctaa aatagctgtt
    25021 tttttgtctg aatcactccc ttgtggtaag gtagtcacat tataatcaat ctcgtttgct
    25081 ttcaatccgt tatttaacca tggcccattg atttcaatgg ctagttgacc agcattcatt
    25141 aaattgtcca tttcggcgcc agaaatcgat tctggaccag tcttgtctac atggatcatt
    25201 ttttggatcg cttttaacgt tttaaggttc tcaggagacg caaattcaga cttagtataa
    25261 tcatcgttca ctaatttacc gccatttgct aacatccagt tatataacgg tgcagttcca
    25321 tccttattga agacaaaacc tgatacattt ttactactat cagttaattt tggtgccatt
    25381 tctgtcaatt cttcccaagt agtaggtggt tgttcagtat ctaatccagc ttgtttaaac
    25441 aaatcattat tccaatacat atacatgcct tgtacctgca tggggacaaa atactgttta
    25501 ccttctactt cacctaattc aatagccgtt tctttaaaat cagatttatc tactccatca
    25561 tattcccaga aatcgtctaa tggttgtacc gctccgtttt ctacatactg tgcaaaatct
    25621 ggataattta atgcaataaa gtcaggtgct tttttagaag aaatcgctgt aggaagtttt
    25681 tcattcaaat tggcccaagt catgatatcc atttcaattt tgatgttttt atcatttgtt
    25741 ttattaaatt cattaacgat ttcttgcaat atttcaccat cagatgcagt aaacccattc
    25801 caaaaagtca aagtcacttc tttatcagaa tcagattctg ctgaacttcc gccaccgcaa
    25861 gctcctaaaa tacctgttgc agctaccaac aaagagccaa ttaaccattt tttacctttc
    25921 attttttgtt cctccttcat ctgataaacg acatctgacc acattccaag atagcggttt
    25981 caataaacaa ttgattttcc catcttcagc ttttacattt gttgaatgac ttggttttac
    26041 ttgttcactt ttaggaagat tagttgcttt tgtatcaaat ccactcattt cagaaaaatc
    26101 aatcactccc tctaatgata attcagacaa gtgaacagtt agattcattt cttcttctcc
    26161 acggttaact gcaaatatga caagttcttt gtcatttatt acggctatac tttctaaata
    26221 cggcacttct tcaaaatctt ccgtcgcata gtttgctgaa cgaatttgtg ggcttaacac
    26281 ctctccttgt ccatacacag cagcttgcat aaatggataa tagatcgtct gtctccaagc
    26341 ttctccgttt gtttctgtcc tgattggtgc aataacattt accaattgag caagacaagc
    26401 aatctttact ctatctgcat gtttcaataa agtgattaat agacagccta atagtaatgc
    26461 atcttcaaaa ttatagttat cttctagtaa aggaggagca atctgccaag gcgctgcttg
    26521 ctcatcttgt tccgctgaat gataccaaat attccattca tcaaaggaca ggttgatctg
    26581 cttcttacta tgtttcttcg ccttgactgt atcgcacatc gctgtcactt cagaaatgaa
    26641 ccgatccatg tctaaggaac gtgcaagata atgagaaaga tcattttttt ggttgccata
    26701 atattgatgc agagacaaat aatctatttg atcgtacgct tgatcaagaa ctgttaactc
    26761 ccaatcacca aatgtaggca tttgccgatt cgaacttccg cataaaacca cctcaattga
    26821 atcatctacg agtttcatcg ccttagccgt ttcctctgct aaccgtccat attcttccgc
    26881 tgttttatgt ccaatctgcc aaggaccgtc catttcattc cctaaacacc atgtcttaat
    26941 tccaaaaggg ctctcttgac cattcgaacg ccttaaatca ctccaataag ttcctttagg
    27001 aaaattacaa tattcgacta aattacgagc tgcatctact ccacgagtac ccagattgac
    27061 agccatattg atttcggccc ccacatgctg acaccagtta taaaattcat gaatcccaac
    27121 ttcattcgtt tcaattgtcc gccaagctaa atccaacctt ctaggtctat ttgctatggg
    27181 cccaatactg tcttcccaac gaaatcctga cacaaaattt ccaccaggat atctaatcat
    27241 gggaatgttc aattctttta ccaagtgaat gacgtcttgg cgaaatccac ttttattagc
    27301 tgatggatga tctggctgat aaatcccttc atatactgct cgtcccatat gttcaataaa
    27361 tgaactgtac aaccgcggat caactttgcc tacacgcttg acactactaa tcaacattgt
    27421 ggcttccata actgacctcc tttaatttat acatgaataa tacacctcgt tgaaagcgtt
    27481 gtcaataata taaatgttaa acttacttat tttttatcga tttt
//
LOCUS       DADQDV010000033        27438 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.033, whole genome shotgun sequence.
ACCESSION   DADQDV010000033 DADQDV010000000
VERSION     DADQDV010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 27438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27438
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.033"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            275..1753
                     /locus_tag="J8S10_001516"
     CDS             275..1753
                     /locus_tag="J8S10_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAZ9630103.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            2030..4090
                     /locus_tag="J8S10_001517"
     CDS             2030..4090
                     /locus_tag="J8S10_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630104.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            4173..4742
                     /locus_tag="J8S10_001518"
     CDS             4173..4742
                     /locus_tag="J8S10_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAZ9630105.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(4917..5723)
                     /locus_tag="J8S10_001519"
     CDS             complement(4917..5723)
                     /locus_tag="J8S10_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630106.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            5861..7375
                     /locus_tag="J8S10_001520"
     CDS             5861..7375
                     /locus_tag="J8S10_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HAZ9630107.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            complement(7778..8761)
                     /locus_tag="J8S10_001521"
     CDS             complement(7778..8761)
                     /locus_tag="J8S10_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HAZ9630108.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(8766..9413)
                     /locus_tag="J8S10_001522"
     CDS             complement(8766..9413)
                     /locus_tag="J8S10_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAZ9630109.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            complement(9498..10130)
                     /locus_tag="J8S10_001523"
     CDS             complement(9498..10130)
                     /locus_tag="J8S10_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAZ9630110.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            complement(10146..10697)
                     /gene="coaC"
                     /locus_tag="J8S10_001524"
     CDS             complement(10146..10697)
                     /gene="coaC"
                     /locus_tag="J8S10_001524"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HAZ9630111.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            complement(10694..11431)
                     /locus_tag="J8S10_001525"
     CDS             complement(10694..11431)
                     /locus_tag="J8S10_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HAZ9630112.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            complement(11428..12417)
                     /locus_tag="J8S10_001526"
     CDS             complement(11428..12417)
                     /locus_tag="J8S10_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HAZ9630113.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIITFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            12675..13217
                     /locus_tag="J8S10_001527"
     CDS             12675..13217
                     /locus_tag="J8S10_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAZ9630114.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            13234..14319
                     /locus_tag="J8S10_001528"
     CDS             13234..14319
                     /locus_tag="J8S10_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9630115.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            14331..15137
                     /locus_tag="J8S10_001529"
     CDS             14331..15137
                     /locus_tag="J8S10_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9630116.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            15138..15965
                     /locus_tag="J8S10_001530"
     CDS             15138..15965
                     /locus_tag="J8S10_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9630117.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            15962..17035
                     /locus_tag="J8S10_001531"
     CDS             15962..17035
                     /locus_tag="J8S10_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAZ9630118.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            17463..20159
                     /locus_tag="J8S10_001532"
     CDS             17463..20159
                     /locus_tag="J8S10_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAZ9630119.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            20236..20724
                     /locus_tag="J8S10_001533"
     CDS             20236..20724
                     /locus_tag="J8S10_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAZ9630120.1"
                     /translation="MFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVNEEED
                     FF"
     gene            20736..21230
                     /locus_tag="J8S10_001534"
     CDS             20736..21230
                     /locus_tag="J8S10_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAZ9630121.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            21251..22060
                     /locus_tag="J8S10_001535"
     CDS             21251..22060
                     /locus_tag="J8S10_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAZ9630122.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            22057..22878
                     /locus_tag="J8S10_001536"
     CDS             22057..22878
                     /locus_tag="J8S10_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAZ9630123.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            22929..25028
                     /locus_tag="J8S10_001537"
     CDS             22929..25028
                     /locus_tag="J8S10_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HAZ9630124.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            25025..26143
                     /locus_tag="J8S10_001538"
     CDS             25025..26143
                     /locus_tag="J8S10_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HAZ9630125.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            26182..27060
                     /locus_tag="J8S10_001539"
     CDS             26182..27060
                     /locus_tag="J8S10_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAZ9630126.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            27251..27403
                     /locus_tag="J8S10_001540"
     CDS             27251..27403
                     /locus_tag="J8S10_001540"
                     /inference="COORDINATES: protein motif:HMM:NF016526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630127.1"
                     /translation="MRIFTGGVHLNSNILCYFMSVVIVIVAYQCMFIFRNVDFIILGL
                     MFEFFW"
BASE COUNT         8765 a         4710 c         5740 g         8223 t
ORIGIN      
        1 taaaagagca ggacggtggc cgtcctgctc ttttttgtgg ttgtttacgc aaatggcgca
       61 aatcttgtac attttaacac aataaaacaa aaaatataga atatttcctc ataaattttt
      121 ccattttttg caatattctc aaaaaaaaga taaaaaatga gaataactga tgaaaaaaca
      181 agcataatcc atcataaaat cagtataggt gaaaagatga actttcatct gcatatcaag
      241 taattggtat gaggcatttt ttgaggtgta ggatatgaag ttggattacc ttatagaaga
      301 ggaagataga gaaaaactgc tgctagctag atatttagaa tttgagaaaa agaattatgt
      361 agtgctgcct aagttatatg aaacattagg tttgtctaaa tttaaaacaa gaaattatat
      421 catagaatta aataaagaat ttactgaatt caaaacaaag ccagagatcc aaatttcaga
      481 agaagcagag atccatgtcg aacgtctgaa tttgacggat atcaaaaatt taagaagaat
      541 ctactttcaa cgatcaaaaa ttgctcgact gttaacggag atcgtggatt caaaagtaac
      601 gatcgaaaaa tttgcagaga atcatttttt aagcatatca agagcctatg taaaaagaag
      661 agaattagtc tcttttcttg aacagcatca aataaagtta aagaaaaaca tattagttgg
      721 ggaagaaata aacatacgga acgtattatt tggggtatat ttcggggtct ttaatggttt
      781 ttctatgcca tttagagaaa gcgtcatgaa tgaagcaaag agtatcgtgc aatattttga
      841 atatctgttc aatttaaaac tgtctgcaac aaaacgaatc aaattcaatt tgctaaccac
      901 tattagtttg ttgagggcct atgggaatca accaatcgga aaacgtttct tttcagatga
      961 atactttaag agctcagaag gaatgaagat catcaaggat ttatcacata tttcttttct
     1021 tcatatccct aaagagcaga tcattgatga gatttcttat atcatgttgt ttttgatcac
     1081 ggaagaagaa tttgaattag atggcgcatt tggacttgcg gaagctcatt ttcatgatat
     1141 ccacatgatt agtcaaaaaa tgtcagtgga attgattgat caattaccat tttcgattga
     1201 aatctctgaa gaagaaagac tatatatacg aaaagaactt cgtatgggta tgatgcatgt
     1261 caatcgaaaa aattggatat tcgactttga gatgactagc tttacgtcta aaaagcagct
     1321 acagtttttc ttcgagacgt atccaatatt cagtacagca atccaaaagg tcatacaaga
     1381 gaataaacgc tatttcttgg gaaaagatga acgtttcatg attcgcttat tttatgatta
     1441 tctcttttta ttggtcggta tttgtccggt atcatatttt gaagcaccga ttcatgtctg
     1501 tattgatttt tcgcaaggat ctgcttatac cgattacatt atttctcaag tgaaaggatt
     1561 taaaaattac aatattgtga ttgagagtcg aatcacttct cgtacgaata tttatttatc
     1621 tgattgttta cttgaaaaat ttaataaaga acagataatt tggaaaaatc caccgactcc
     1681 agatgactgg gaatattttg gaaataccat catcagagaa aaaaatagac atttaactga
     1741 aaaaatcagc tagtatttat ggatggcagc tttgtctcac atatttatta gctgatttat
     1801 gtttttttca aagaaaaggt aactagatat aactagatat aactagatat attacttaac
     1861 aaaattaaaa agtacataag ttattattcc gattttcttg aaacaataaa aaatcaaaaa
     1921 aaatactctc ctaatagtcc atcttctttt gattttattt atataatgaa atcatcttat
     1981 gaaaattact acttcatgtt tagacaagag tagggaggac taagaataaa tgtgttcaaa
     2041 aagacgttca aaacaactaa ataaacacgc ttgtcgttta gataaggaac ggtcgtgttc
     2101 tgaaaaacac tacgttaagt ttatgatgcg cacgatgctg atcagtttat ctgtaggtgt
     2161 ctatatgcat gtacccgttc aggcaacgac acaaaccatc aaggtcgtac gtacctctgt
     2221 ttctgagacc actgattccc ctatcactat tactcatact ttcactgatg caaatggaaa
     2281 acagctactt cctgcattga cttcctataa taaagtcagt tatcctccaa cgataaacca
     2341 ctactggtta attcctaaca aaacattatg gacatcggaa accggaagca gtgtgccgct
     2401 ttctatcttt tccgatatga ctgatcctac aaaaggtgat cagttaaaac agatcactga
     2461 tattttgaat catgctttga cagatataaa ggacggtgga agcgcacaag tttcttatgt
     2521 atatgaaaaa gattattcac agtttgaaag aaagaaaatc gatgttctgg cagggacaaa
     2581 agtttcgata tctgatctgg tagaaaggct gaagaacgca gatggaacac aaggagatat
     2641 gtccaaagta atttcaaaca atgggaatat cgtggatacg actaatacag gaacatctac
     2701 tatttccttg tcctattttg atccaattgc tttaaaaaca atgactgcat ctgctgtgat
     2761 ccatgttcgt gctgatcaaa cagctatcaa aggaaaagat cttcacttaa gaacaggaga
     2821 gagttacgcc cctaaagatc ttgttgaata tgtaacaaaa agcgatggaa cttcaggaaa
     2881 taaagaagaa atcaaaatga acgggacagt agatactaca actccgggag aatatcccgt
     2941 tgtattaact tatatagact cgaaaacatc aaatgtggca gaaacaacag ctgtagttta
     3001 tgtagaagca tctgctgctt catcgactgt catcactcat tttatagata gtcaaacaaa
     3061 taaagaactt caagcagaaa cacatatgag tagtgtaaat cgtattcctg atttgcgcct
     3121 acctgctgaa ttttctgatc gagtgccaaa tatagattta tcgacttatg aacaaaatgg
     3181 gaaagtcact tctatttctg attggatgca agcaaacgga ttagacagaa aaagtcactg
     3241 gtcggagatc cttgaagtac ttcactcaga actgatgaat aataggaagc aatcaggagg
     3301 ggaaattacc tttacttatg tttatatacc agacaatcgt tcattagaag gtcatgatct
     3361 tattgttcat ccaaacgaaa aaataaacaa agaagagttg atccaatcag caacaaattc
     3421 cttaggtaaa cccgtaccgt taaaggatgt atcggttaca atcaatgaag taccattgga
     3481 ggatggttat ttgaccaaac aaacaggtga ttttacgatt atgtatagtt atcatgaccc
     3541 gtattcactc caagaactcc atgctcagtc actattacat gttttaccat taaacaaaca
     3601 gatagatcaa aaagaacaaa aaagacaaga agaaagcttg tcagaaaaaa aacaacaaat
     3661 ggctcatgca gtttctccaa cagggaaagt aaaacaaaca agaagcctag agttagcaag
     3721 aatatctaga aaaatctcag aatctaataa aacgataagg caagaagctc atttggcccc
     3781 acaagtttct ggattggaaa atgaaatttt agagcctaaa ataaaacaac aatcagaaaa
     3841 agaatttgtt gctaaacagt cggaagatca gaaggaatca gatgaccaga aggaaacgaa
     3901 gaaaaaacgc ttgtcaacta ttgattccac cgatgagcat ctgcagccgc aagtaccact
     3961 tcctagtccg ggaacacccg cacctggtgg aggtattcct tcttctgctt taggagattt
     4021 catgcgaggt atggcaggaa catgggtata cgctaatcga aatgaatttg acgcagatga
     4081 ctggttctga tttatatctc tatctgttat agtcaaataa gtagctgagt catatgttat
     4141 ttggcataat ggagacgagg agggatagaa aaatgttaga taaaacgtta ccttacgcag
     4201 aaatctggat gacaagacca cttcaacaaa atgttccaat cacgccttta gcggaaggtt
     4261 ttgaatttcg attttatcaa aaagaagatg aatctgcttg ggcggagatt gagacttccg
     4321 ttggggaatt tcaaacgaca gatgaagcac ttgagtattt tcaacaaaac tttgctcctt
     4381 atcctgaaga acttgaaaga aggatgtttt ttgtagagac aaaaaaagga gaaaaagtag
     4441 caacctgtac cgcttggcga aaaaaatcaa gagagcaagt gtatccggtt tttcattggt
     4501 tagcagtgaa accagattac caaggaaaag ggctcgcaaa agcattgact gccagagtct
     4561 tgcaagaatt tcctaccctc catacggacg gaccaatcta tcttcacaca cagacatgga
     4621 gccatcaggc gattgctctt tataaaaaaa tgggttttac ttttattgct gaaaatctag
     4681 acggcacacc taatccagat tatgaaaaag ttatgcaggt tttaagtaaa ttagataaat
     4741 aacgaaatgg tgaaataagt cctcagtatt gggataaaaa acgaaatagt cattcctcat
     4801 atcttacttt tttgagttaa tactatcgga taactaatgg catgccatac attcaaaaaa
     4861 gaaggggcag tgacaaaagt attgtcactg ccccttctct tgttttttag catgttttat
     4921 cgtttgattt ttttaggaat aaaattcttg atgaacgtaa atttttggta atcgtttcga
     4981 ctatagaggt aaccaaatac actgaaaaca actgctccaa taaaattaac aaataaatcc
     5041 ttcatagtat ccatgattcc cacgtctaag taaccatttt ggatgattgt tttatctgtt
     5101 ttaccatctg cattttgact ttcaatgatt gtccgagtga tatctggaac atgatagaca
     5161 gtgtttccgt ctttacttaa ctccacacta ttgatttgct ggatgatcgt atctttttgc
     5221 atatcgaatt gcagtaattt atctgctgaa aattccacaa actcccacat aacaccaact
     5281 gtcatcgaaa aacagaagga aacaactgct agtaataaag gagtcaagtt catggttttt
     5341 gtatttttat tgagcaaata aacaagggaa aagccgacac ccccagctaa aaatccgctg
     5401 aatgcatgta gaaaagtatc ccacattgaa aaatagccat aaaaatcact taactctcct
     5461 aaaactgttg aactaaaaat aaaagataac aaaatgattt ctagcatatt tggaatctgt
     5521 atctttaata tcttttccag aaaataaggg atttcaaata aaattaatgt cagtaataaa
     5581 agcattgtat ttccccagtg ttggttccag acctgatcca ctagcataat aacgacgatg
     5641 atacgtaata aaatatagat tccgtttgtg attctacctg cagtttttgt actgttcgta
     5701 aaaaaggttt tcaaatgatt cataaaataa ctccttcatg tatatcctta attatactaa
     5761 gaagcgtgtg tttaccaaag ctatatgact taaagaaaaa cagagttgat attgtgaaaa
     5821 aaatcactta atatagtata aggagaaaag ggggatacaa atgaaaaaat tagttgctgg
     5881 tttattaaca gccgttgcac ttcttgctat gagcgcatgc ggcgcagatc agaaaaatac
     5941 agcgcagaca agttctagta cgaaggaatc tgccgaagta tcatcaggcg cttctgaaca
     6001 agtatataca gatccaaaag aaatgaaaga atcttatgat gtcgtgatta ttggagctgg
     6061 tggtgcaggg atggcagcag ctatcgaagc aaaagatgct gggttgaatc cagtaatttt
     6121 ggaaaagatg cctgttgccg gaggaaacac atctaaatca tcaagcggta tgaatgcttc
     6181 agaaacaaaa tttcaaaaag aagaaggaat caaagactcg aatgatgcct tctatgaaga
     6241 aacgctaaaa ggtggtggag gaacgaatga taaagaaatg cttcgatact ttgtcgatca
     6301 ctctgctgat gcggtcgatt ggctagatca aaacggtatc aaactggaca acttaacgat
     6361 cactggaggg atgagtgaaa agaggacaca tcgtccgtct gatggctcgg ctattggtgg
     6421 atacttagtg gaggggttat tgaataacgt ccatgagcgg gaaatcccta tttttgtcaa
     6481 cgcagatgtg acagacatta agaaaaatgg ggaaacggtc aatgaagtga ctgtacatgt
     6541 tcaaggagaa gaaccaaaag aggtcaccgg aaaagcaatc gtagttacca caggcggttt
     6601 tggtgccagc aaagaattta ttgaaaaata tcgtcccgat ttagctgatt atattacgac
     6661 aaatcaagaa ggatcaactg gagatggtat caccatgatt gaaaaattag gtggacaaac
     6721 cgttgatatg gataaaatac aaattcatcc aactgtgcag caggatgagg gggtcttgat
     6781 tggtgaggtt gttcgcggag aaggagcaat cttggtcgat caagagggga aaagatttgt
     6841 caatgaaatg gatacaaggg ataaagtatc tgcagcaatt acagcattgc ctgaaaaatc
     6901 agcttatttg atttttgacc aaggcgtgcg tgatcgtgcc acagctattg aattttatga
     6961 ccaaaaagga tatgtcacaa ctggaaagac aatggaagaa ttagcagaaa aaatcgattt
     7021 accaaaagaa acactagcaa aaacagttga tggatggaat acggatgttg cggagaaaaa
     7081 agatgctcaa ttcaaccgtg ccacagccat ggaacatgac ttatcgtctc cgaattatta
     7141 tgcgatcaaa atcgcaccag gaatccatta cacgatgggc ggtgtgaaaa tcaatacgaa
     7201 cactgaagta ttagataaag aaaaccagcc aattaggggg ttatatgctg ctggtgaagt
     7261 cacaggtggc ttacatggaa acaaccggat cggtggaaat tcagttgcgg agatcattat
     7321 ttttgggcga caagcgggca tacaagcagc tcgatttgct tcggaaaatg aatgaaatag
     7381 aacgtaaata aaaagaggtt gtgaaatcag cgttttgagc taataccgag ggtcagctga
     7441 ttgaacactg tttagtgaag aggttgtgaa aaagctgccc tgcatcaagt aataagaaca
     7501 gccaagtaaa aacagcttct tatgttttta acttggttgg acttattacc gcagatgcaa
     7561 gcttttgaac accgtttatt cggaaaaaga gcgtgggaca aaagtaaaga acacttttgt
     7621 ctcacgctct aaacacgtat aaacggcgga agcagaagaa attccttcgg aaataagctg
     7681 aaattcacaa aaatttgaaa agcaattttc gtgaatttct tcttatttct tggagttaaa
     7741 cgcttctgtc ccagcctctt ttttgatcag catgatttta ttcagttatc ttcaaaatga
     7801 tttttccgat gtttttgttt gcttccatat attcatgcgc ttgtttgact gcgctgaatt
     7861 ggaatgtacg gtcaatgatt ggccgaatct tgccattttc tagaaaaggc ccagcttttt
     7921 gcataaaagt ttgtgcgagc tctgctttat actgatcact tctaggtgtc aataatgtac
     7981 caagcagttg gacacgtttc ccaatcaata caccaaggtc tatctcaggc acgatggtcc
     8041 cacctagcat accaatcaag acccaacgtc catcaacggc tatagaagct aaattctttt
     8101 cccagtaaga agcgccgatg aaatccaaaa taacatcgac tccccgacct tcagtgattt
     8161 ttcgtacctc ttcttgaaag tcttgttttt tatagttgat caattcatct gcaccaagtt
     8221 ctttacaaaa ggcgagtttt tcttctgatc ctgcagtaac gatgattttc gcgtgagaaa
     8281 gctgtctagc taattggatc gctgctgttc ccacaccact tgctcctgca tggatcaaga
     8341 cagtttcgcc ttcttgtaat tttccaagcc agtaaagtgt ttgataagca gtcaaaaaaa
     8401 cttctgagat tccagcagca gaaacatagt ctagcgtatc agggagaagg attgcacgat
     8461 cggcaggcat cacagcatat tcggcataac cacctagatt gactaatccg tatacttttg
     8521 tcccaggagt aaaagtggag atatcacttt tattctcaac tacctctcca gctacttcga
     8581 ctcccaaaat agggtaggga ggtttcaaag agactgattc tcttttcata atatctgttc
     8641 gattgacagc tgctgtatgg actttgatca gtaattcgcc ttgttttggt ttaggaacag
     8701 gcacttcaat ttgttctaat acatctacag aaccaggatg cttgattgaa atggcacgca
     8761 tggatctatt cctcctttgc ccattcttgg aatgctgtat tcaactcttt gctaccttca
     8821 gaaagtacta gagtcgtacg agaaatatcc gtttcttcca ctagagcggc aagtacagca
     8881 gcaactgtag agcgagtgat cgtttttgat gccttctcat taggcttagt taattgaatg
     8941 gaagtaactt cttcatcgtt agtcaatgtg actggttgaa gaatgacaaa atctaagtta
     9001 gttcgtttca gccattcatc tgcataatgt ttagtaatat aataatctgt catggactca
     9061 ggccattttg ctggttcatc tgcataaaca gcactgacca tcagatagcg agagacatgc
     9121 gcattttcag ctgcgatcac tgttttgatt gcgccatcca agtctacttg cagaagattc
     9181 tttccttgag agccggcagc aaaaatcaat acatcgatgc ctttgaatgc ttcggtcatt
     9241 ttttccacgg accaagttaa atcaaaagag acatacgaaa cattctcttt ttttactaat
     9301 gtttgggaag caacatctct cacccctgca aaaatttcat gggaacttgg agctaaatct
     9361 tttatcaggt gtcggccaat ttgtccgttt gcacctacaa caaaaatttt catttggatc
     9421 atcctttcga cgtcaaatct ttccattcaa tagtaacacc aaaagagaaa aaaatcagag
     9481 atcggctacg atgactatca gttagtaaga gaagggtgct tgaagtatct taacaagaca
     9541 ttgcatactg ctgcagtcgc aagacctgcg acgattcctt caggtatacc acttgtaaaa
     9601 ataaccgcta gaatagctga ataaacagca tttaaatttg ttccgatgac tttggcataa
     9661 tcttgctgga ataaaaagta gatcatattc atcactaaaa tcgtattggt caatgaaccg
     9721 gaaagtccag ctaagaataa agaaacggaa tctgcttttt gtttcattag tttgcgcaga
     9781 cctttataaa cgaaataagg aaccacccca atcaagatgc gaggaataaa cgcgatcagc
     9841 aaggctttcc agcttccatg ttctgttccg atgactggga taaacggaga aaagacaaaa
     9901 gacaaaggtg tttggataac tgtgctacgg atcatgctga tcagtccaaa tgtaccgcca
     9961 agaaaagcac ctagtcttgg tcctaaaacg atcgaagcaa tgattacagg aatatgcatg
    10021 gttgttgcat tgattggacc gatagggata aaacctaaag gcgtaacagc taataaaatc
    10081 aaaatagcta aaaacatcgc agttaatgta aagttttttg tatttttcat aagtactcct
    10141 tttttctaag catttctttc attaagagtc agcatgacct gttcgatgat cgtctgaata
    10201 tcagctaagg caccttttcc aaaatctcca caagctaaaa gagattctct tggttcaatt
    10261 tcctgatagc cgacagatct caatgtttcc agattacgct gagtgatcgg gttttgatac
    10321 atattcgtgt tcatggcagg ggcaatcaat tttggtgttc ccactggaag cgccattgcg
    10381 actgttgaaa gaagatcgtc tgcaatgccg tttgctagct tgccgataat gtttgctgta
    10441 gcaggcgcga tgagaaacaa gtcagcttgt tttgctagtt cgatatgatt gattacctgc
    10501 ggatttgatt cttgcatgac gtctgtatgg actgcgcgct tcgacagaga ttgcaaggtt
    10561 aatggcgtga taaaatgtgt gctgctttta gacataatca catctacctg ggcacctaat
    10621 ttgacgaatt gacttgtaag atcagcgctt ttgtaagcag aaatacttcc agtaacgcct
    10681 agtaagatct ttttcatttt gattcctcca gtctaatttt ctcagtaatc aatgcagcaa
    10741 tctcagattt actttgagct tcttccactg ttccatcttt agataagaga tagccgtggt
    10801 gtgtctcgcc atggatttcc gtcaaatcat ttgcgaaaat aaaatcagtt ttgttattta
    10861 tcagactatt ttttgcgact gccagaagag attcctttgg tacatctact aatagtttga
    10921 aaccaatgat ttttgctttt ggctgccatt cacgtagata agaaatgatt tttggtgttt
    10981 tcttcaaaac gagcacaaga tgctcggtgt tagaagagat ctttgaaaca gtggtatctg
    11041 tctgttcatt ttccgcaaac caattgtcca gttcttcttg cgttgaagaa gtgggtaggt
    11101 tttttgccag ctgttcttct gaaaaactaa aagcaggagt aaaatcactg actgccatac
    11161 tgtggataat cgcatcgtag tgttcttttt tcgttagttc ttctaattgt aaaaataagt
    11221 ccagtgcaga ttcgatcgta taaatcgtta tattggagtg tcttttcggt ttcagtgctt
    11281 gtttcgtagt cacgtaatcg attgtggtat ccggattggc agctaaataa tcagctaatg
    11341 cttgccctaa tcgtcctgtc gaatgatttg taatagcacg tacttgatcg attttttcag
    11401 tcgttcctcc agctgtgatt agaatcttca tttatggtca cctacattta ctagtgttct
    11461 tccttggtgt gttccagcaa gtagtttaga tgctgtttca ggcaattgat ccagagtaat
    11521 ctcttggacg accagttcat ctgcaatctg caaatccgcc atctgttgcc ataaagaaag
    11581 acgttgatct attggtacat tgacagaatc aattccaatc aactggatgt ttcgcagaat
    11641 aaaaggcaag acagtcgcgt ttagtttgat tcccccagca ttgccacata aagctactgc
    11701 accgttataa gagatcaatg gaagaagact gcttagctgc tcgccaccta ctgtgtcgat
    11761 gacatagtcg atttgctgtt ttcctaaagc ttttgttgtc tctggcagaa attcatcagg
    11821 tcgtacgact tgcaaagcac ctagactttt tagccatgtg acagactctt cttttctgga
    11881 aaaggtaatg attgactgga atcctagttt atgtaacagg gctatcgctg tactgcctac
    11941 accgccagaa gcaccagtaa cgacaacttt tttatcggag gtcatacctt gacggattaa
    12001 agcgttcaca cacaacatag cagtaaaccc tgctgtacca aggatcatcg cttgacgcag
    12061 cgtcatattt tttggtagag gaactaacca gtctcctggt actttttgat attggctata
    12121 accgcctgga tgggtgacgc caagcccaaa accagtagca agtacaagat cttcttttga
    12181 aaaacgtgga ttgttacttt ggacgacagt tccggataaa tcaatccctg gagtcatcgg
    12241 atatgttcgt atcacctgac cagactcgct cattgccaat gcatctttat aattgacatc
    12301 agaataggca atttttacca agacttcatt ttcagccaac tcagtaaatg gcagatcact
    12361 gattgctgta tggaaaacag gttcctttat tacctgaaaa gatcgaaaag cgttcattcg
    12421 tgagacactc cttttaaaat tttcttttat cataccataa agcctactct tttattcttg
    12481 ttcttccgta aatttagaca aaaattaggt gaaaaataaa gaatcaaaca actagaattt
    12541 attccaaaag ataaagaaat attcagcaaa aaaaatttta caaagggttg cctttttcaa
    12601 taaatttcgt atactaatac gagtggtagt aaacaggaag tttactatta gaaaacttcg
    12661 attcggagga aattatggaa attggtgaga agttaagaaa tttgcgcatc caaaagaatt
    12721 tgacacaaga agaactaggc gaacgcacag atttgtcaaa agggtatatt tcccagttgg
    12781 aacgagattt aagttcacca tcaatggaaa cattcttttc tattcttgaa gtcttaggtg
    12841 tgactccaga agaatttttt catcaagaag cagcgaatct gcaagtggtt tattcaaaag
    12901 aagatcatac ggtttatttc gatgaagaaa acgggtatga attggaatgg ctcgtggctg
    12961 attcgaatga aaaagaaatg gagcctgtct tgctgacttt tgaaggtgca ggagaatata
    13021 agacgtttga accttcatta tctgaaacgt ttatttttgt attagaaggg gaattagagt
    13081 taagcttagg agagacggtc tatgtggcaa aagcaggaca gtcgatctat tatcaagcga
    13141 caaaacaaca tcaattaagg aatcatctca aaaaacgaac aaaagtattg attgttgcaa
    13201 cgcaatcata tttgtaatat agggggtaaa aacgtgggga aaccaatcat ttcatttgat
    13261 caagtagtga aacgctatga tgatgaaaca gtattaaaaa aagtaagttt tgagatcgaa
    13321 caaggaaaat tttatacact gcttggtcct tccggctgtg gtaaaacaac gatcctacgt
    13381 attatagctg gattcaccga agctacagaa ggggacatct attttgaagg gaaacggttg
    13441 aatgatttgc cagctaataa gcgacaagta aatacagtct tccaagatta tgcacttttt
    13501 cctcatatga atgtttttga taacgttgct tttggattga agatcaagaa aatgtccaaa
    13561 tcagatatcg aaaagaaggt aaaagatgct ttgcgtatgg tccagcttcc tggatacgaa
    13621 aaacgggaga ttagtgaaat gtctggtggt caaagacagc gtgtagcgat tgcacgagca
    13681 attgtaaatg aaccgaaagt attgctatta gatgaaccgt tatcggcgct tgatttgaaa
    13741 ctacgtacag atatgcagta tgaactgcgg gatctgcaac aacgattagg aatcacgttt
    13801 atttttgtta ctcatgacca agaagaagcg ttggcaatga gtgatgagat ttttgtcatg
    13861 aataaaggga aaatcgtcca aagtggtaca cccgtagata tttatgatga gccaatcaat
    13921 catttcgttg ctgattttgt tggggagagc aatatcgtgg acggtgtaat gatcgaagat
    13981 aatctagttg agtttgttgg taagcaattt gaatgtgtcg atggcgggat gcgtctaaat
    14041 gaaccagttg aagttgtttt acgcccagag gatttgacga tcacgacacc agataaagga
    14101 aaactagtcg taacggtcga tactcagctg tttcgtggtg tccattatga aatcatctgt
    14161 tatgatgaac agcaaaatga atggatggtc cattcaacga aaaaagctaa agaaggaagc
    14221 aaagtaggat tggcctttga gccagaagat atccatgtca tgcgtttcaa cgagtctgaa
    14281 gaagaattcg atgcacgtct tgacagctac gaagaatagg ggggacaaga atgaaaacaa
    14341 tgcgcaggat ctattccgtc ccttatattt tgtggctcgg tttattcgtg atcgcgcctg
    14401 tattaatgat catttatcaa tctttttttg atatgaatgg gcaattcacg ctgaataatt
    14461 atctatctta ttttacgtcg gggacatcgc tttctatgac gatcaattct gtatggtatg
    14521 catttttgat cacgtttttc acgctgatca tcagttaccc gactgcttat tttttaacaa
    14581 aactgaagca caagcaatta tggctgatgc tgattatttt gcctacatgg gtgaatctgc
    14641 tgcttaaagc ttacgcattt attgggattt tcagtgtgca cggcagcgtg aatcatttct
    14701 ttgattttat cgggatcggg ccgaaacaga tattattcac agacttcagt tttctgttcg
    14761 tggcaacgta tatcgagatt ccatttatga ttatgccaat tttcaatgca ttggaagaga
    14821 tgaatccttc tttgatcagt gctagtagag atttaggcgc gaatagcttt gagaccttcc
    14881 gacgagtgat ttttccgtta tcattaaatg gtgtgaaaag tggtgtccaa gcagtattta
    14941 ttccttctct ttctttattc atgctgactc gtctgattgg cggaaatcgg gtgatcactt
    15001 taggaacggc tatcgaacag catttcttgg ttacacaaaa ctgggggatg ggttctacaa
    15061 tcggtgtgat tttaatcatt gctatgttca tcgtgatgct cctgacaggc gagaagaaaa
    15121 aaggaggtcg ctcataaatg aaaaaattta aatggtcgta tctttattta gggatcgtct
    15181 ttttattctt atatgcaccg atcttctatc tgatttttta ttccttcaat gaaggaggaa
    15241 cgatgaacag ctttacagga tttacttggg aaaattatga agctgttttt gaagatacac
    15301 gtttgatcat tatcgtattg aatacgttca tgctggcttt cttatctgca ttgatcgcca
    15361 cgatcatcgg gacatttggg gctatgggaa tctattacac gaaaaaacga cgtgcacgga
    15421 cagcgttgtt gagcatgaat aacatcttat tagtctctcc tgatgttatt atcggtgcta
    15481 gtttcttgat tttctttaca ctactaggat tcggattagg ttttcagagt gtattgcttt
    15541 cccatattgc tttcagcatt ccaatcgtcg tcttgatggt cttgccaaaa ttgcaggaaa
    15601 tgaacgattc aatggtcgat gcggctagag accttggtgc taataatttc caagtagtca
    15661 aaaatatcat tttgccttat ctttctccag gaatcatagc tggatatttt atggcattta
    15721 cctattctct tgatgatttt gcggttacat ttttcgtcac aggaaatggc tttacgacgc
    15781 tctcagtaga gatctattct cgtgcaagac aaggaatcag tttagaaatc aatgcgctaa
    15841 gtgcgttagt tttcttgttc tccatgatat tggtcattgg atactacttt attagtaaag
    15901 aaaaccgtcc aaaacggctg aagaaaaaca gaagagtacg cgagggggtg gcacggctgc
    15961 gatgaaaaaa ttacaatctc tgtttttagg tattctcatc attattgcgg tgctgctgct
    16021 tggtgttcgt caacttgaaa aaacaagtgg catgagtgga gcaaaggtac ttaccatcta
    16081 taactgggga gattatatcg atcctagttt gatcacgaaa tttgaaaaag aatatggata
    16141 caaagtgaat tatgaaacat ttgattctaa tgaagcgatg ttcacaaaaa tccagcaagg
    16201 tgggacaaac tacgacatcg ctataccaag tgaatatatg atccaaaaaa tgatcaaaga
    16261 aaaactagta cttccattag atcattcgaa gatcaaagga ttaaataata ttgatccacg
    16321 atttttagac ttggattttg atccagataa tcagtattcg attccatatt tttggggaac
    16381 tttagggatc gtatataacg ataaattctt tgatgcaaat caaattaagc attgggatga
    16441 tttgtggaag ccggaattaa aagacagttt gatgctgatt gacggtgcac gagaagttat
    16501 ggggctttct ttgaatagtt taggctattc tttgaatagt aagaatatgg cacagctgac
    16561 agaagcagca aataaattga atcatttaac accaaatgtc aaagcaatcg tggcagatga
    16621 gatcaaaatg tatatgatca atgaagaagc ctccgtggca gtgacatttt ctggcgaagc
    16681 tgccgatatg atgtgggaaa atgaacattt acattatgtg atcccaccag aaggatccaa
    16741 tctttggttt gataatatcg ttatgccaaa aaccgtgaaa aataaagaag gtgcctatga
    16801 tttcatcaac tttatgctag aaccggaaaa tgcggcacaa aatgcagagt atattggtta
    16861 ttctacacca aatgaagaag caaaagcgtt attgccaaaa gacatttcgt cggacgaaca
    16921 attctatcca tctgatgaca cgatctccca tcttgaagtc tacaaagatc taggatcgaa
    16981 atacctaggc atctataatg acctattctt agaattcaag atgtatagga gataatggca
    17041 aaactcagta agaatgggga cttatcaacg ttctaaagag ctaaaaatcg tcctttttct
    17101 atctgagttt tccaatcttc taccaaaagc ggatgaaacg ccgctttttt tgtgttattt
    17161 tattttttct accacgtttt tctaccagag aaaagtggac aaaaccattg taaaataggg
    17221 cccgagacgg gctagtaaat ctaagattga aaaagttaca gaaggataaa gtaattggaa
    17281 actatgcaaa tatacttaac ccttctgtaa tctattaata aaactaatat atgaatccag
    17341 ttcaatattt gtagctatga aaaaacataa aaatcatatt agataaaaac taaattggta
    17401 gataaattat tttgtcagat atctgaggca aatattcgac tatttgtgtt tcaaagtaaa
    17461 aattggaata caaatataga atagacatat tgcagccgat agtttattat gcttttagac
    17521 acattaaact ggaggaaaaa atgaaaaaga gcgctaaaga tcgagttttt gatgagctga
    17581 tacgactaac agggaatatg tcttctgtca ctgccgagaa aatttcgaag aatctaggta
    17641 tctctcgtca gaatgccagc cattatttga cgagattagt ggaagataaa aaggtcgaga
    17701 aattaccggg aaagcctgtt ttgtggaagc ctttagatga atatgcggtt gtagataata
    17761 cggagcaaat aaacgaagcc tttcattctg tagttggtca tgacggaagt ctgagagagg
    17821 tcattcaaaa atgtatagcc gctgtcaaat atccgcctaa cggactcagt gtattaataa
    17881 atggagccac gggtgttgga aaaagttttt tagccacaaa aatttttgaa tacgctatcc
    17941 atgagcaaat tattgaaaaa gatgcaccat ttgctatctt aaactgtgcc gattatgcgg
    18001 acaatcccga actgctttcg gcaacactgt ttggatacaa gaagggggcc tttacggggg
    18061 ctgaaaagga taccgatggt ttattggcaa cggccaacaa cggctatctt tttctcgatg
    18121 aggtccatcg cctatcgaaa gaaaatcaag aaaagctctt tctatttatt gatactggaa
    18181 actatcgtcc agtcggtgaa aatgtaaatt ggcattctgc taaggttcgt tttattttcg
    18241 ccacgacgga aaaaggtgaa aattatttat tagacacctt tgatcggcgt attcaaatta
    18301 gtgttatgtt gccaactttt gaagatcgcc ccattcgaga acgattagag ctgattcaat
    18361 tattttttca aaatgaagcg gatgttttac aaaaagatat tattgtttca agagaagcct
    18421 tgtctttaat gttatctcat ccctttagtg ggaatattgg taagctgaag aatatcatta
    18481 aaatcagttg tgcggatgtg tatagtcgaa cacaagaaga accattaacg attgggaaaa
    18541 atgagatctt gattcagtta aatatgctgg aatccgaagt agaaagcttg ccgattgcta
    18601 gtttattgat aaagaaaaat caaaagataa aaacggatcg aatcaaaccg tttgattatg
    18661 attcgatttt ggaaaaaatt actcagctga taaatgaagg taatttcaat gaaaattttt
    18721 cttcgataaa gaatgaagta cagcatttgg tgcatcacat tgataaggat tcttttttat
    18781 caatgagtag aaaattgatg attcagatgt ttagaaaggt ctgggtatcc gttttaggaa
    18841 aaacgtacgg attgacgacg agtggacctg ttgcagaaat tattagcaga tcctatgtca
    18901 tttccccaag ctataagaca gacttaaccg ggataaatcg tacattagct gcaaatctac
    18961 ctcggacgac ttacttatgt aatcagttct tggagcattt accaccgctc tcagaaaagg
    19021 acgagaactt tctaagactg cttattgtcg tgactttatc tgattatgta gatgaatcca
    19081 tcgagctgaa gggcctgttg cttgctcacg gagatagtac ggctagcagc attcaagcag
    19141 tagtgaatca attatgcggc aattatgttt ttgaagcgtt ggatatgcca gtagagagta
    19201 atgtgtcaga gattgtcgaa tcgacaagga atttcgtgaa acggcaagtg aatacagata
    19261 gtctagtgct gatcgtagat atgggctctt taaatcaaat ttacacacag atcaagaacg
    19321 atttaaaagg ggagttactt cttctgaata atttgacgac ttccattgca cttgatattg
    19381 gcttgaagat gacgatgaat gcgccattta aacagattgc ggaggatgca gcagacaagt
    19441 attcaatcaa tgttcaatac tttgaaggct tttctcaaag tagcaacatt atcatttcct
    19501 gtatgtcggg tttggggatt tcggacaaat tgaaagatgt ttttcgtcat catttatcgg
    19561 atgaatccat cgaagttttc acgaaggact acagagaact acgtgaatta atcgaccaaa
    19621 atgatgaaac ttattttgac aagacaaaat tggtcatcac gacttcggat cttccacgtt
    19681 ccttttcaat tcctaatatt aatgtttatg acatcttaga cggtgatgga gcagccaatt
    19741 tggagcatat tttgagtcct gaaatgaagc cggcagaatt taaccgcttg attcaggagc
    19801 tagtaaaatt cttttcgttg gaaggaattg cggaccgttt gaactttctg aacccaacga
    19861 tcgtgatgag tgaagtggaa acagtcattt ctaaatatga aaattactat catttcactt
    19921 taaatggccg tgtaaaacta aatctctata tgcatacggc attgatgatg gaacgtttat
    19981 tcttggctcg gacagaaaaa tctgaagaac cgaattatga tttgaaacca gatgaagatg
    20041 aattttatta tgtttctaga agtatttttc aatcaatgga gatgaaatat aattttaaag
    20101 tcaatgctta tgagctttcg ctgctctatg aattattagg accgtatatt caaaaataaa
    20161 gtgtctaaaa aagtgtctaa tctgtttttt ttaggttaga cacttttttt aatgtgaatt
    20221 aacgtgatta aaccaatgtt tttaaaagtt ggcacaggaa ttgcttatat aaaagtgaac
    20281 agaaagaaag gaattaacca tatgaagaaa attctaatag cgactcacgg tcacttagct
    20341 tcaggctttc ttagcagtat tcaattactg acggggaagg ttcaagagat tacggtgatt
    20401 aatgcttatg tggatgagtg tgattttgaa caggagttga atgtatttgt aaaccaggtg
    20461 aacgagcagg atcagatttt tgtttttacc gatttatttg gcggaagtgt caatcagaag
    20521 attaccaaaa cctttttgga gaaagagatt gctgtaacta ttttgtctgg ctttaatctg
    20581 ccaattctgc tcgaaatagt attggcaacc aaggaattaa caaaggagga tattcaggaa
    20641 ctggtaaata aatgccaaca ggaattaaag atgaccattc ttgatgaggt acatgtagta
    20701 aatgaagagg aagatttttt ttaggaggaa gaaaaatgat taaagcagtg cgaattgatg
    20761 aacgattaat tcatggacaa gtagcgatga cttggacaaa gagtctaaat ttaaccgggt
    20821 tagtagtagc aagcgatgag gcggctacca acgatattca aaagatgaca ttgaagatgg
    20881 ctgcaccatc gaatgtcaaa gtcattatta aaacagttga tgacgcgatt catttgttaa
    20941 aagatccgcg ggcgaaggac atgcgcttga tggttttagt ccctaatgtc aaagatgcgg
    21001 taaaagttgc gaaagctttc ccaacggaaa tcgaattaat gaacgtgggg aatgctggga
    21061 aaatgacacc gccatcggaa gataagaaaa ccttatcaaa ggaagtgatg ttaacgacgt
    21121 cagaaattca agacttaaaa gaattagttg aactttatcc agataccgtt tttcagccta
    21181 caccggcgat ggaaaaacgt tcagctatct ctattttgag tgatttttag aaaaaggaag
    21241 gagaaaaatt atgtatgatg catttgtagt cgctttggcc gtttttattg gagttgctgg
    21301 acatgaaatg ttcgggatgt ccatgctgag tcgtccgatt gttgttgctc cgttagcagg
    21361 agcgttgatg ggggatttgc agacggggtt gattgtcggg gcgtcactag aagccatctt
    21421 tatgggtgtc gtcaatatcg gaatctctag tacggcggag ccttctttgg ctgctgggct
    21481 ggctacagcg ttcgcaatca aaatgggagg aaacgtggat gcgattattc ccattgtctt
    21541 tccactagca gtattaggat tacagttaat gaatatgatt ttttcttttg tatgtggacc
    21601 gatggctgct aaatttttca aatttgcaaa atctggtgat caaaaaggaa tcatcaatct
    21661 gcacttcttt atgtggtttg tccactatgc gctttatgct cttattccat tctttgccgt
    21721 tttatttgga gcagatgttg tcaaaagcgt cttggataat attccagagg tcatcatgaa
    21781 cggattaaca gtcgctggaa atctgctgcc ggcagttggg atggcgatgc tgttacggat
    21841 gctttggagt aaaaatattg ctgtgtggtt tttctttggg gccgttgtta tggcgtatct
    21901 cgagttacca ttgattgcaa ttgccgcagt tggaacgatt attgcaattg ttatagccca
    21961 aagagatcta caactaaaaa atatatctgt tcatgcagtt caaagcgatg ctgctgtaaa
    22021 tgcaacgctt gaccaagaag aggaggattt ctttcaatga aattagctga tggaatttct
    22081 aaagatgaga aaaaattggt tcggaagatg ttttggcgct cgatgactat gtatgcttcg
    22141 gtgaatccgg tgacgatggg cggcggtggt ttcgcctatt ctatgatgcc cttcattaat
    22201 catttctaca aaagtgaaga agatcgagct gcggcgctgg aacgtcatac acagtatttt
    22261 tcgacgacca ttccttgcgc gtcctttgtc atggggattg cggcatcgat ggagaaggaa
    22321 aattctgaaa aagctggttt tgacgtggaa agtatcaacg cgatcaaaac gagtttgatg
    22381 ggaccattgg ctggaattgg cgattcattg ttctggggag tttggcgtgt cgttaccgcg
    22441 ggactagcga tcaacttagc caatgccgga aatattttgg caccaattat ctttttagtt
    22501 atgttcaata tacctaatta cttgatgcga tactatggcg gcgttttagg ctattcatta
    22561 ggctctaaat atattgaaaa gctgtatgcg aacgggttaa ttgaaattct gacaaaagct
    22621 gctagtatct tgggtctgat catggtaggt gcaatgacga tcagtatggt caaattcaat
    22681 accgttttga gcttttcaat gaagggcgaa gaactaatga atgtccaaga aatcctcgat
    22741 agtattttta aaggaattgt accgttattg gtaacattga gctgtttcaa attactagat
    22801 aaaaaagtcg gcgtcatcaa aattattttt ggaatggtcg tcttgggaat tttattgtca
    22861 ttacttggaa tcgcatagta ggaagctgca gctactaggc tgcagttttt ttagcaagga
    22921 gggaaaagat gactattaat gaagtaattt attcacccaa acacccattt tttaatgctg
    22981 agttaaacga cggaaatgtg actacttcaa acgaatacag ctactatcgg aatattcctg
    23041 atgtaaaggg attgaccttc gatgtaagta atcaaaagac attagcaaac cttgatgttt
    23101 gcgggacgat tcaaacgttg accttttatc gagaaaattt actaactgag gaaaaaccag
    23161 gtgtttgggt caataaacag ctctctcaaa ccaattcgtt atccttaaag gttgaagtaa
    23221 acgggattgt ctaccatttg tcagaatcgg atcatcgtat tgaagtcgat gtgattcaag
    23281 actgtttgcc tagatatatt catcattatt cgacgtttaa ggtcattgta gtatcctttg
    23341 ctcccatact ggctaataag cgtttaagta tgcttgttca acaggtttac attgtgaatg
    23401 aaacacacga aagccttcaa gtttcagtga aagatgtgcc ttcgtatcaa gagaagtatt
    23461 cggatcagca aaatgtgttg atttctcaaa aaggaaataa ggacacgatc gcacaacagg
    23521 aagtggcaag cttcgccatt gcttttgtgg acccaaatgc ttttgaagaa gtaatgactt
    23581 ttcaggaatc tgatatcgaa aaatggctga aggaaacatt gaactatttt gctcagctat
    23641 ttgggcagct gtcaatgcca aacgatagag ttgtccatct ctatcgtcgt gcactttatc
    23701 aaagcttttc tagtttcggt atgaatcgac agggacaggt cgtcggcagc aattggggca
    23761 gctatcctgc tactaatcga atttggaata aggatatgta ttacgcatca ttgccattca
    23821 ccatgtttga accggagtta tgtcaaaaaa cggttctatg gtttgatcaa tatggcgtta
    23881 agtttcctgg ttcaaaattt acaggaggta tcaatcattc tctgagtaat tcgttatcca
    23941 gtgcgttact ggctagtctt tattttgaac atactgggga tacaaaattc tttgagcggt
    24001 gtccgcaggt tctactgaat gcttcaagaa ttattgagga catattagct caacgtcggt
    24061 caggggaacc aatgcttttt ccatctgttt ggttatcaga cgcctttgca cttggaaagt
    24121 atcataccgg cagcaatctt tgtctttgga aggcctgtat tggacttgca gaaatttttg
    24181 aagccctaga acaactgagt cttagcaagc gatacaaaaa cattgcctgt aaactaaagg
    24241 aatcaatttg taaacaaatg actatcgatg gtccttttgg tgagcaattt ttggagggaa
    24301 tcggtgatga ggagaaaaca acctattcag tgaagcacta tcaaaaaccg attcttgagc
    24361 aagggttaat ctttttaagt gatgtgattg tggatggaaa aattaattta ttgatgcatg
    24421 atggagaaga atcagacact acgttgatgc ctttttatca atttttagat aataaagatc
    24481 atttatatca gaacaccatg gccttttctg ctagttcttt caatccaacc tatagcgagg
    24541 aaatcaaagg catcacttgg ggattagaat ccggcgccac ttttcctggc tttatcactg
    24601 ttttaatgag cgagctgcac aaccctcaag ctttcgtaac ccgattagaa gaactaattt
    24661 gtttggcaga tttagacggt tcgtggtggt ggtggccgta tcgcttagag gctcaacaag
    24721 gagaagtcgt gcgagacttt ggctgcggca aatgcggctg ggcatcgggt ctttttgtca
    24781 gcctaatgat cagtcaatat ttcggattga aattcaaaaa aggagtattg caaattgatc
    24841 ctgttgataa tttaacgttt tcttggaaga atttgaagtt cggtcaagcc ttcatttcga
    24901 ttgaatgtac gcaatccgag ttgagtattt caaatttgtc agaaaagcca ttgaaaataa
    24961 gtgatacgaa aaaaattctt cacgtagaaa agggaaaaac gattcacatt caaaggagaa
    25021 aaagatgagt atactaaaaa atattaccca atttaaaaaa atccagagtc gagcaatcac
    25081 tcccgaaaat ccaacaggcg agaaaggtaa agctgcgatg ttgccaagcg agctaggacc
    25141 aagccgcaaa ggtcgtggcg caattccgct gacttctggt gaagaaactg tgattgcgga
    25201 tattactgga acgggaataa ttcgtcatat gtggatgacg attcgtgatc gaacagaatt
    25261 tggcagtttt gttttacgtg atttaatctt aagaatttat tgggatgggt cggatagccc
    25321 tgctgttgaa agtcctttag gggatttctt ttgtaatggg tttggagagc gttgcgaggt
    25381 gaactcgttg ccgatagtgg ttaatcctac agggggcttt aattcctatt tcgaaatgcc
    25441 tttccaaaca tccgctaaaa ttacgatcga gaatttacat ccgaaggata tgtcctcatt
    25501 tttttatacg ataaattacg ctttggtgga cgaattggaa gaaaatagcc tatattttca
    25561 cgcaaattgg catcgggaac gcattaccaa attacaggag gattataagt taattgatcg
    25621 attaaagggt caaggctatt acgtgggtac ttaccttgcg cttacctgcc tagaacgtta
    25681 ttggtggggc gaaggcgagt ttaaattcta cattgatggg gatagtgagt atccgaccgt
    25741 aacctcaaca ggttcagaag attattttgg cggggcgtgg gcctttcatg agtacgatga
    25801 gttcggacgt ccacatgcga aaaactattc aacagccttt ttagggtatc cttaccaatc
    25861 aaatagagat gccacaagag atcgttttga aacgggaaaa ttgaatgccg ttcatgcctt
    25921 tggtgacgac gcaatgccac gacatggtct ttatcgttgg catcttcaag accccatctg
    25981 ttttaccgaa gatttatcgg tcactttaca acaaatcggc aacgatgatg ttcgcttatt
    26041 tgagcggcaa gacgatgttg ctagtgtcgc ttactggtat tcaacagaag cttcaggaaa
    26101 tactaaacgt catttcactg atcgagaacg cttgccgcgt taatgaagtg tttttcacat
    26161 attcgaaggg aggaacctat gatgatatat ggggcaattg aagctggagg gactaaattt
    26221 gtctgtgcag tcggtactga ggaattaacg attttggaaa gagtcagttt tcccacaaca
    26281 actccagttg aaacaatgaa gcaggtcatt gattttttta aaccttttaa ggaacaattg
    26341 gcaggcatcg gggtcggctg ctttggtcca attgatattc aatgcaaatc aacgagtttc
    26401 ggtcatatca catcaacacc aaaacttgct tggcaaaatt tcaattttgt aggaacgcta
    26461 aagcaatatt tcaatattcc gattgaatgg acaacagatg tcaatgcggc ttgctatggt
    26521 gaatatgttg ctggttctgg caaagggtta gcaggtgttg catacttcac tgtgggaaca
    26581 ggtatcggag gtggtgcctt gttcaatggg actttcgtgg aagggttcag tcatccggaa
    26641 atggggcata tgttgatcaa gcgacatcca aaggacaatt tttcaggaaa ctgtcccttc
    26701 caccaagatt gtttagaggg gatggcagca ggaccagcga ttgaaaaacg gttgggtgta
    26761 aaaggccaga atttattggc tgacgattcg ttttggcaga ttgaagcctt ttaccttgcc
    26821 caatgtgcat acaatacaac actgatgttt tcgccagata gaattatttt tggcggtggt
    26881 gtaatgaaac aagaacacat gaagaaaaaa gttcaggata aatttgttga gcttataaat
    26941 ggatatgttg aaataccacc aattgatagc tacattatta cgcccgaatt aggtgataat
    27001 gccggaataa tcggcggatt agcattggcc agaaaagcgg taagaaataa gcaaccataa
    27061 ttaatgaatg tttcattgat actcatgtca aaagtattta accgagtaat caaatgatca
    27121 aatgaagttg gataaagcga aaatgaattc aaataaaaag gctctaagtc aaatcgtgtt
    27181 gttttcatta aatcactgaa aggaaatgct tctgcgtttc cttttttctt tttgttgtgc
    27241 gctgtatacc ttgaggatat tcactggtgg cgtacactta aatagtaata tattgtgtta
    27301 ctttatgtct gtggtaatag ttatagttgc ttaccaatgt atgttcattt ttcgaaatgt
    27361 tgacttcata atccttggct taatgtttga atttttttgg tgatagattt tttcagccgt
    27421 ataaaataaa tcgtaatt
//
LOCUS       DADQDV010000034        27232 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.034, whole genome shotgun sequence.
ACCESSION   DADQDV010000034 DADQDV010000000
VERSION     DADQDV010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 27232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27232
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.034"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(161..445)
                     /locus_tag="J8S10_001541"
     CDS             complement(161..445)
                     /locus_tag="J8S10_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630128.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(463..1353)
                     /locus_tag="J8S10_001542"
     CDS             complement(463..1353)
                     /locus_tag="J8S10_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HAZ9630129.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFALDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(1373..1591)
                     /locus_tag="J8S10_001543"
     CDS             complement(1373..1591)
                     /locus_tag="J8S10_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630130.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(1561..3261)
                     /locus_tag="J8S10_001544"
     CDS             complement(1561..3261)
                     /locus_tag="J8S10_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HAZ9630131.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            3528..4301
                     /locus_tag="J8S10_001545"
     CDS             3528..4301
                     /locus_tag="J8S10_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630132.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(4382..4951)
                     /gene="thiT"
                     /locus_tag="J8S10_001546"
     CDS             complement(4382..4951)
                     /gene="thiT"
                     /locus_tag="J8S10_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HAZ9630133.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(5017..5119)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(5125..6096)
                     /locus_tag="J8S10_001547"
     CDS             complement(5125..6096)
                     /locus_tag="J8S10_001547"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HAZ9630134.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(6190..7563)
                     /gene="glmU"
                     /locus_tag="J8S10_001548"
     CDS             complement(6190..7563)
                     /gene="glmU"
                     /locus_tag="J8S10_001548"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HAZ9630135.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(8066..8884)
                     /gene="purR"
                     /locus_tag="J8S10_001549"
     CDS             complement(8066..8884)
                     /gene="purR"
                     /locus_tag="J8S10_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HAZ9630136.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(9051..9875)
                     /locus_tag="J8S10_001550"
     CDS             complement(9051..9875)
                     /locus_tag="J8S10_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HAZ9630137.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(9848..10528)
                     /locus_tag="J8S10_001551"
     CDS             complement(9848..10528)
                     /locus_tag="J8S10_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HAZ9630138.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(10551..11489)
                     /locus_tag="J8S10_001552"
     CDS             complement(10551..11489)
                     /locus_tag="J8S10_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HAZ9630139.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(11734..12585)
                     /locus_tag="J8S10_001553"
     CDS             complement(11734..12585)
                     /locus_tag="J8S10_001553"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HAZ9630140.1"
                     /translation="MELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADHLFFE
                     EITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAGLGGG
                     STDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQVLPS
                     MPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMGNSLE
                     DITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGFCEEV
                     YLVRTLQ"
     gene            complement(12739..15312)
                     /gene="mprF"
                     /locus_tag="J8S10_001554"
     CDS             complement(12739..15312)
                     /gene="mprF"
                     /locus_tag="J8S10_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HAZ9630141.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLP
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            15453..16259
                     /gene="proC"
                     /locus_tag="J8S10_001555"
     CDS             15453..16259
                     /gene="proC"
                     /locus_tag="J8S10_001555"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HAZ9630142.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLTDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(16338..17894)
                     /gene="rny"
                     /locus_tag="J8S10_001556"
     CDS             complement(16338..17894)
                     /gene="rny"
                     /locus_tag="J8S10_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HAZ9630143.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(18305..19354)
                     /gene="recA"
                     /locus_tag="J8S10_001557"
     CDS             complement(18305..19354)
                     /gene="recA"
                     /locus_tag="J8S10_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HAZ9630144.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(19463..20704)
                     /locus_tag="J8S10_001558"
     CDS             complement(19463..20704)
                     /locus_tag="J8S10_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HAZ9630145.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(20944..21522)
                     /gene="pgsA"
                     /locus_tag="J8S10_001559"
     CDS             complement(20944..21522)
                     /gene="pgsA"
                     /locus_tag="J8S10_001559"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HAZ9630146.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(21731..22615)
                     /locus_tag="J8S10_001560"
     CDS             complement(21731..22615)
                     /locus_tag="J8S10_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAZ9630147.1"
                     /translation="MAFETIGEKLRQARLNKKISLDELQQITKIQKRYLEAIDNDDFD
                     QLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQPETVSTSRKAMHQ
                     EESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDTASSLKVEGSVEES
                     SSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITDATKPVTLEFTAVN
                     RVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNATIKANGESVPVNP
                     GENNQSPKNVNLTLQYAE"
     gene            complement(23392..24678)
                     /locus_tag="J8S10_001561"
     CDS             complement(23392..24678)
                     /locus_tag="J8S10_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HAZ9630148.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(24671..25939)
                     /locus_tag="J8S10_001562"
     CDS             complement(24671..25939)
                     /locus_tag="J8S10_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HAZ9630149.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYPDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            26191..26652
                     /gene="mscL"
                     /locus_tag="J8S10_001563"
     CDS             26191..26652
                     /gene="mscL"
                     /locus_tag="J8S10_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HAZ9630150.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(26711..27157)
                     /locus_tag="J8S10_001564"
     CDS             complement(26711..27157)
                     /locus_tag="J8S10_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAZ9630151.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGQ
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
BASE COUNT         7741 a         5873 c         4723 g         8895 t
ORIGIN      
        1 taataccgag aaaatggttt ttgaacatca cttattcaaa ataaaaaaag attgtgacac
       61 gaattttgtc acaaccttta aatgtattcc tagagcaaag aagctaagcg aagaaatcca
      121 attctgatta tttattgtat ttctttgttc agcatccttg ctaaaagccc atattggaca
      181 aagtattcac tacacccatg atctcatctt ttcgagaacg tgctttttct gtcggatctt
      241 ctacctcttc tgtgtcaatt cgaacaataa atttccgatt catcgtcacg taagcaccgt
      301 cgttgatcaa aataaacagt tcgttctcat tatagtctgc acaggcatct ttccatacgt
      361 caaagccgtt tttttcagaa gggatatccc gtttaaccac agtttttcca cttaattcgt
      421 ggaacgttac gtcataatat ttcattatct ctacctcttt cgtcattcaa tattttgtac
      481 ttgttctctg attttttcta agatcgtctt agactggacg acttgatttt taatttcgat
      541 tgcatttgat ttggaaccga tcgtgttgat ttcccgattc atttcttgga tcaggaaatc
      601 taattcccga cctacaggac attgtgcttc gataagttca tctagttttt gtacatggat
      661 cgccagacga tccagttcct cgtgaatatc tccgcgttcc aacaagatgg ctagctccgt
      721 caacaaccgt tgctcatcga ctttcgctcc aagaaattcc tccagctttt tttgatacct
      781 tatttgaaat tccttttcat agatttctac aaaactatcg agttttttta gtacttcttt
      841 gaattcttca gtattctttt tcaacactaa agctaaagct tgaccttctt tttctcgact
      901 cgcctcaata gaatcaagtg cgcttttcaa tgtatctaga gctaactgtg ccaattcttc
      961 catgctctct tccggttttt cttctaccgt tacgaagttt tcgtccagcg cgaagcgttc
     1021 cgccatccga ctaattgaca cttgattttg actaccgtat cgttgttgaa ttccgtctgt
     1081 caattgagtg ataagtgaat caatcaattc ccagttgatg acgatctgtt tttcgttttt
     1141 gccaatataa gctagattca caaatacttc gattcgaccg cggcttaact gctgtttaat
     1201 aagctgacga aaatcgtttt caacaaagtt caggatttta ggacttcgta tttgaacatc
     1261 tagaaaacgc tggttgacac tttttatttc aatatctaac tgatacgctt ttgtttcgcg
     1321 gatggctttg ccaaaaccag tcatactttt cattcgacag ggtccttcct cattacatat
     1381 tttctattgc tttttgcagt tgttcaaact cttcgttcgt caatgtcagg cctttcccca
     1441 ttttttcatg gtctggcgcc caatctcgaa gatcgaattt tggcgggcga ccattccagc
     1501 tgactaggtt cagttcttta cgccacccct tgttgttttc tgacaatata gcgatttctt
     1561 ctacgatttc atatgaaaat tcttgtgcca tggttgttcc tccttgagat aatataaata
     1621 taggatcagt aatgtgtcaa ctggttgctt aagcaattca tgctgcaaac gatccttgcg
     1681 ttttccttgt agcagataat caaaataaac agttttcgtg cgctcatttt gtattttttg
     1741 ctggtatttt cgataccttc gccattcttc agtacttaat tgaccaattt gtgccaataa
     1801 atcatccggc atacttttta tatcttgttg gcagatcatt tgaatcatca tgtctacttg
     1861 atagatttca ttgggcagta aaaaatgttt ttttgctaaa agttctagca tcgccaatcc
     1921 gcatgtctct ggtacgaccc tgttcttata taaattacgc agtttttgcc aaaattttat
     1981 gcttttgaaa aaagataatt ctaactgaat ttcttttgtt aagtaagaca aaaatcctcg
     2041 ccagtatgtt cttgcaggtt taacagaatg aaatgtatac cagttcccat agtaatagcc
     2101 taatcgtttt ttcatttcca gatagcctaa ttgtaaattt aattggttcc tttggctatc
     2161 aaaaagcaga aagctgccta gtgtccacaa tgtttgacat ttccaatgga taaaaatgtc
     2221 tggcatacga atttttttcg ctgggcctgg cccttgcaca tctacgacaa atgcctctgt
     2281 tgctcctttg ttaatcgcaa tatcaatagg tattttgttg cgatacccac cgtctgcata
     2341 tttatttttt ccgatctttc gataagccat agcgggataa aatgaagcag aggcgagtat
     2401 ccaatctggt atttcttctg tttttgtctg ttggatatca gtcactactt ccgctagttc
     2461 tggcagttta gtagacaccg tatataaacg tattttggga ttatgtttga gtaaggacaa
     2521 atccaaattg tctttgacca tcttttccaa tggagcagaa gaaaccccgc cttcaattag
     2581 tgctgttttc gtcatttggc gtctttctcg atagaagcgt tcacgaaggt cttcaactgc
     2641 agccatttct ggtaacgcaa gcacttgtct tgtcgacagc tttttccata aattcacagc
     2701 ttttttcata tctccttgta aaatcaatgc gccgttcaac gcacctaccg aggtacctgt
     2761 gataatctca aagttgatat catgttcctt cagcgcctgc cacacaccaa tctgataagc
     2821 accgtgcgct cctcctccac ctaaaacaag tgctgtatga tagaccagct ttttatttaa
     2881 ttgtgtggtt ccttgatagc cgtttttatg aaaaatacgc aaccattctt ctgatagagg
     2941 agattgaaat aaaaaacaac agttttcttt aataaaaaaa cgagcgcaag cttccatata
     3001 ccgaaaaaat tttttccatt caaaagtttc accttcaatc aacagattat taaaaataac
     3061 atctcctcta cttttagcaa tagtaaaata gacggtatat tttttcgata ctgctttaaa
     3121 agcacattgc ttttttgcag aacgccaaaa agcgtctcta ctttcttgat gactttgaaa
     3181 aaatggaagg ggttgttttg cttgctggat aggcgaatac agcgacattt tctgtgaaaa
     3241 gtaaactttt tttatctcca tcgcgctctc ctttttcttc aagtatacca gtacgtcata
     3301 aaaaggtcat gagtctcgta ttcgactttg tagattccat aagaaaacaa ttcataaaac
     3361 ctcctttaaa taaaaaaata caaaaatcac aaaaattaat tgaaaatgag agtgttttca
     3421 atgaaaacgt gattttgtaa tggaatttta aaataaaaga aacaagcttt tttaatgcaa
     3481 atgttgtaaa ataaaagaga ttaagaggaa ataagaggag gaacatgatg actgagtcag
     3541 tttatgtaca tattgatacc acaagtaatg ctgttttaac aaaagggctg actgctactg
     3601 actttgcaaa cagtatcgtg cattttcctc aaaacttgct cttgcttgat ccatctgctt
     3661 ctgctggaga atatgaatcc catacagggc tgaaagtaat ccgtggtaca gaaaatattc
     3721 agcgtttctt ttcctcttct cgtaacaggc gtggattcga tgaattgaag tggatcgact
     3781 ttactgattt aacgatgctg aaagaattga cacctttaga aatttcagaa ttattatatt
     3841 ttggtcatat gaaaacacat cttcattcgc cgttttttta taaactacag aataattttg
     3901 tatacttcga tcttaatgat cagctgaatc ggatttatta tcgctattta gatgaatttt
     3961 ataggatttt tgctagtaaa ttaagttcga tcttgtcaga taagatcaat gtaaaaaaat
     4021 cttttttcaa aaaagaaaca cctgttgaaa aaatcagtgt ggaattattg aaagaaatgc
     4081 gtaatttgat gcaggaaggg atcatttttt cttttgatca agttggtttg atcgatggta
     4141 aatatcgtat cccaatctat gtgattgaag attatatttg gaaattaaaa ggcacccggt
     4201 atcgagaaga ggaaatcatc gctactttaa tctactctgt caccgatcga cactggcaat
     4261 tggtagaaga tgccgatctt tcttatctgc cattgaagta gatctatttc ttatcaaaaa
     4321 ataaaaagga aacaagaaac taggacatga ttctgtctca agtttcttgc ttctttttta
     4381 tttacagctc ctgtcgttta tctggcacaa aaatcgaagg agtcgtttgt tggatcccta
     4441 ataaaacgat gatcgttaca atagctgtac tcaacccgct ggcaccattc attacgaaag
     4501 aaaagagcca aggattcatc ccccatagtg catacgctcc ccagaaaacc actcctgcaa
     4561 taaaatgcca aaaatatctg gaaagtgcgc caatcaatgc accaaacacg atgctttttc
     4621 taatttgttt cgtattatcg tctacatagc ctttttggac atttgaagcc atgagccctg
     4681 ctgcgcctgc aaaagtatag gcaatcgggt actcaatcaa cacttgaacg acacttaaat
     4741 aataaacttg tcccaacgga aaatgtagga tgccccaaat gaaacctgcc agcatccctg
     4801 cctttgtccc tcttcttaac gcaaaaagag tcaatggaat ctgccctaat gaaatagaaa
     4861 aactgctgcc gatctggatc ggaatcaacg acaacaccat cgctaacgct gcaacaatcg
     4921 ttccttctac ccaaactcta ttttttccca taaaaaaact tcctcctttg aataaaaaag
     4981 tcacaaagga ggaagcagct ttcgaaaata gtcaaacagc tgtttattca caattcctac
     5041 gctcgcataa ccgatacagg tacgaagggt ttagaaatag attcaatctc agcccaattg
     5101 gactcccctt tgtgagttta tttattattt attttttgtt tcaaacaatg gactaactgg
     5161 tttgttttca tggatacgtt tgattgcatc tcccattagt ccgccaacac ttacttcatc
     5221 gattttgtcg attttacgat cttctggaag atagatcgag tctgtaacaa ctagacgctc
     5281 gatagctgaa tcttctattc tttgtaaagc agggccggat aatactggat gtgtacatga
     5341 agcatacaca ctagttgcac cagcttcttt caaagcattg gcagccaatg tgatcgtacc
     5401 tgctgtatcg atcatatcat cgatcagtac acaagttttg cctttgactt gtccaatgat
     5461 attcattact tctgcaacat ttgcttttgg acggcgtttg tctatgatcg caatcggaga
     5521 tttcaaaaat tccgctaatt tacgtgcccg tgtgacacca ccatggtctg gtgaaacaac
     5581 gacaacatca tcgcctttga ttcctttttc taagaaataa ttggcaataa gtggcgcacc
     5641 catcaaatga tcgactggaa tatcaaagaa accttggatt tgaactgcat gaaggtccaa
     5701 agtcagcatt cttgttgcac cagctttttg aatcatgttt gctactaatt tcgctgtgat
     5761 tggttcccgt gcacgtgctt tacggtcttg acgcgcatag ccataataag gcatgactac
     5821 gttgattgtt tttgcacttg ctcgtttcag tgcgtcaatc atgatcagca actccatcaa
     5881 gttatcattg actgggctgc tcgttgattg aataacatag acatgcgatc cacgaatact
     5941 ttcttcaatg tttacttgaa tttctccatc actaaattga gtaacagatg attttcctaa
     6001 ctcgacgccg actgctgctg caattttctc tgctaatggg cgattggaat ttaacgcaaa
     6061 aatttttaat cttgggtcaa agtaatgttt tgacatgggg acctccactt tctttttcac
     6121 aactctagaa ttctacctaa taaatagtag tcatattttt taaataaatc aagtgatttt
     6181 gcaaaagtct tagtttagat aagggagttt ttttgcatat ccttctttat tgacttgtct
     6241 tgctctcgca attgccagcg catattctgg aatattgtct gtaattgttg acccggcagc
     6301 aatcgaactg tttttagcta cctcgacagg tccgatgata ttcgtgctag aaccaataaa
     6361 gctgtggtcg ccgacagtcg tatgatgttt gttctttcca tcatagttga cgaagacaac
     6421 accacatccg acattgattt cttctcccag cgtagcatca ccaacataag tcaagtgacc
     6481 gactttagtt cctttgccga tttgagcatt tttcacttcc acaaagtttc cgatatggac
     6541 gttttcgcca atttcagctt ttggtcgtaa atgtgcataa ggtcccacat ctgcatgttt
     6601 cttgacatgg ctgctttcaa tgactgagtt ttcaatgacg acgtgatcct caatcctact
     6661 gtctacgatt tttgaatgtg acccgatgac acaatcagaa ccaatgactg tatttccttg
     6721 gatttgtaca cctgcttcga tcaatgtgtc tggaccgatt tctacgcctg catcgatgta
     6781 tgtcgttgct gaatcgacaa agcttacgcc attgaccata tgcatctggt taattcgctt
     6841 tctcatgatc tcatttgctt tagctaacgc gatccgatca ttgactccca ttgattcttc
     6901 aaaatcatcc gtttgataag cagcaactgt atggccttct tcttttaaga tttcgatgat
     6961 atctgttaga tagtattcac cttgagcatt gtttgttcca actttgctta acgcatcgaa
     7021 caaagcttcg ttgtcaaaac agtaagttcc tgtattgatt tcttgtacaa gagcttcttc
     7081 tggtgttgca tctttttgtt ccacgatttt ttctacgatc ccaatatggt cacggatgat
     7141 tcgtccatat cctgttgggt tttctgcttg tgccgtcaag atcgttgcac ttgcattttt
     7201 tccttggtga tattcaaaaa gattgttcag cgtttcagta gtcaataatg gtgtatcgcc
     7261 actgataact aacgttgttc ctttttttcc ttccaagaaa gaagcagctt gcaaaacagc
     7321 atgtcctgtt cccaattgtt ctgcttgtaa cgcatattta ctgcgttctc ctagttgtgc
     7381 tttaacttgt tctgctccgt gtccaacgat cgtaatcact tcatctggtt tcgtttcact
     7441 gacccgatta atgatatgtt ctaccatagg tttaccagaa acgggatgta aaactttata
     7501 taattttgac ttcatgcggg tacctttccc tgccgccaaa ataattgcat aacgtgcgtc
     7561 caactgcgtc actcctaaat atagtttgct gatttcagtt tatcccagta tacccatttt
     7621 ttcaacaaaa caagtgattt tcttttatcc cagcgttttc tggataaaaa aatagataga
     7681 ccataacggg cctatctatt tggtaaccgg tgctctcctg ccaactcctc ggtcacaagt
     7741 cacactactc ataaaacatg aaaagctgtt ttttgaaatc gtttcttgtg acttagagtt
     7801 aaacggtagg cttacaacct cttcattaaa cgtttttcaa tcagctgacc ttcggtatta
     7861 gctcaataaa cggcaaaata tgaggagcaa tttttccgtt tattgagcta atactcagga
     7921 caggacgctg atttcacaac ctctagataa acggtgttca aaagccagtt tctcggtatt
     7981 aagccaaatt tatgaaaaaa tgtggaaagc cattttcaca aaatttttct tactactcga
     8041 aactaagcag ctttttcaca acctcttatt ctgaaaaata atttcctggc acaaccgtaa
     8101 tatttttcgt ttgagtatct acatctttga cataaagcag tgacgtataa tcatcgatgg
     8161 cgcgatgacc gttgaatttt gattcggcaa atacagtgat gccaacaagt tctgattcga
     8221 attcttcaat caagctcttc attccgttga ctgttccgcc gcctttcatg aaatcatcca
     8281 ctacaaggac acgtgaacca cgtttcaaac ttctcttaga cagttccatc ttttcaattc
     8341 tttcagaaga tccagacaca tagttgacac ttactgttga tccttctgtt atttttgagt
     8401 cccggcgtac aataacgaat ggcgcattca gataatagga cacagcttgg gcaataggta
     8461 cgccttttgt ggctacagtc attacagcat cgattttttc accaaggtat ttagaagcaa
     8521 tgattcttcc aacttgacgc agcagttcag gttctcctaa caaatcagag agataaacat
     8581 atcctcctgg aagcagacgg tcttgttctg atagacgttc tgctagagat tcaatatatt
     8641 ttttcgcctc ttcatatgaa atttcaggga tgaacaatac accacctgca gcacccggga
     8701 ttgtttccaa ggttccatac cctcgttctt taaatgtttt cttgatgatt cccaaatctt
     8761 cactgataga agatttagca gattcataac gttcggcaaa gcttgttaag gaaatcaatt
     8821 catgcgggtg attcaataaa tactgtgtca tgtcaactag acgttcactg cgacgtactt
     8881 tcacctattc caactccttt taagaaattt tatcgtttta cattatataa gtttttcttc
     8941 aaaaattcga gcattttatg aaaaaataag aaaatagttc ggtatttatt aaaataaaaa
     9001 gaagcctata aaaaattttt cgtttttata aggcttcttt tctttataat ttagttattt
     9061 tttcttctga aggcaaccaa tattcgtttg atgatattta caatcaggaa caaagcaata
     9121 aagactaatg tgattgttgc tcctggaggt gtatctagat aaaacgagct agttagtcct
     9181 gacagcatcc ctagaaatcc tacacaaaca ctgatagcaa tcacgacatt gaagcttttg
     9241 cctaatcgca taccgattgc tgcgggaaga accatgattg cggatatcaa aagtgcaccg
     9301 gcaatcggga tcatcacagc aatagccaca ccagtaatca cattgaacat catcgacatc
     9361 aaatgaacgg gtagcccatc cacgtgggcg gtatcttcat caaaagtcag aacatacatc
     9421 ggccgtttga ataaaaagaa caatataccg atggcaacga ataagattcc taaaaagatg
     9481 acttgctccc atgtaatggt cacgatcgaa ccaaacagat aggattggat acttgttgct
     9541 gaattccctc cgctcaaatt catcaatact aacgctagcg ccaaaccacc agccattaaa
     9601 atggcaatgg agatttctga ataggttcgg tagatcgttc gcagatactc caatatcaca
     9661 gctgctaata caacgactag catggtcgta agtgtaggat taaggttcaa aaagaatcct
     9721 aacgctaccc ctgctaaaga gacatgagaa agcgtatcag ccatcagcga ttgtcttctg
     9781 atcactaaaa acacacctag catcggggcg attccggcaa tgaagatagc ggcaagaaac
     9841 gctcttctca tgaattcata tgaaagcaac gccattgaga atcctccttt ctcaccagtc
     9901 ggatctgtct gtccgcatac tgtttgatat cttcatgatc atgggtgatc attagaactg
     9961 atttcccatg gacatgcgca ctatgtcgga gaagacgata aaattcattt ctggattctt
    10021 catccatacc tgttgttggt tcatcaagaa caaataagtc agggtcagta gcaaaaatac
    10081 gcgctaaact gattcgctgc ttttgtccgc cagacaattc acctattcgc cgatttcgca
    10141 tatcccacat ccctacagct tctaaagcac gctgtacatg ttgatgatct ttttcagaga
    10201 gacgcttgaa ccagcggcct cttggatatc ttcctgaacg gactaattcg atcaccgtac
    10261 taggaaaacc tgcattgaaa gatgcaactt gttgaggaat ataaccgata cttaattttt
    10321 ttccttcttg atttttctca gcaatcttta tcattccttt tgaaggtttc agtaatccta
    10381 acgatgcttt caccaaggtt gacttggctg ctccattttc tccagttaaa atgacaaatt
    10441 cacccgcatc tacatgataa gagacatctt ctagtacagg ttcatcatca tagtaaaagg
    10501 tcaaatcaga tatttcgata taacgcacct tacaacctcc attctaaaac ttaattgata
    10561 ctttctttta aagctttcag atttttttcc atgacagaaa tataattttc gcctgctttg
    10621 atttgttcat tagtcaagct ttctaaagga ttcaacactt ctagcttcac tcctgtttca
    10681 ttcgacaatg tctcagctac cttcgaagag gcattttctt caaaataaat cactttgatg
    10741 ttgtttttct tcacaaattc ttttagctca gctaagcgac ttggtgtggg ttcctgatct
    10801 ggtgaaacgc ccgaaatcgc tacttgtttt aagtcgtatt gattcgctaa ataagcaaaa
    10861 gcagcatgct gagtgacaaa tgtgcggttt gttgcatctt ttagctcatc ggagtatttt
    10921 tgatccagtg cttcaagctt tttgatataa gcatcggcat tcttcgtaaa agtttccttt
    10981 ttatctggat atttttcgcc taattcttca gcaatcgttc tgacttcttt tatagctaat
    11041 accggatcga gccaaacatg tggatcgtat tcatgtgaat gaccatgccc ttcttctgat
    11101 tcttcatgtt cgtctgcttc ttgcgattct aaacggtcga ttcctttagc tgcttcgatc
    11161 atcaaggtct gtttgctatc cactgaatcc tttaacgaat ccacaaaaaa ttccatgtct
    11221 gaactattat acacgaaaac atctgcatcg gaaatttctg ctctttcttt tgcacttggt
    11281 tcgaaatcat gcggctccgt tccagcaggg atcaaaagtt tcacgtttcc ttcatcccct
    11341 acgatctctt ttgtaaaatc atacatcgga taaaaagtcg taacgatcgt caaatcctct
    11401 tttttgtctg cttccttgtt cgtatttcca catgctgcaa acagtaaagc acctatcatt
    11461 accgtagctg tcaaaagata ttttttcatt tatatgctcc tttcaatgaa caaatcggaa
    11521 ttttacgatt tattaacgtg aactaatgta tcaaaataaa aaaacacagt caatagaaat
    11581 ccatcaattt ctgatttaag catgtatatt cttgattaaa tcgtaaaatg gatgagttgc
    11641 tgctcatatc tagccatttc actacaataa aaaactgaag aataccattt taggattcct
    11701 cagtttttca tcacctattt tacttcttat attttattgc agggttcgta ctaaataaac
    11761 ttcctcacaa aaacctttta acccattata tactctctgc gctcttgaat aatgttgaca
    11821 caaggcaaaa acggttggtc cgcttccact catcaatgca gcatctgctc cgtacttgat
    11881 catacgctct ttgatttgat ggatgactgg atgccgcttt cccgttatat cttctaaact
    11941 gtttcccatt tttttgatca tctgctgata atcttgctct cggatggctt cagcaagtcc
    12001 gtggatgtct tgatgttgga tggcttgcgt atctacttct ctaaacactg tacgtgtaga
    12061 gacactcatt cttggtttga ccaacacaac ccagcactgt ggcatagaag gtaatacttg
    12121 gatttcttcc cctttgccac cgacaaatgc cgtacttccg tagacacagt aaggaacatc
    12181 tgtaccgact tccaaaccga tttctgccag ttcttctaac gaacagccca gattccataa
    12241 ttggttgatc cctcttagag cagctgcaca gtctgtactt cctccgccta atccagctgc
    12301 tactggaata ttcttcttaa caaagatctt gacaccggtt ttgatattgt atttattttt
    12361 tagcaataaa gcagcttgat aaacattgtt ccgttcatct accggtaaaa atgctttatt
    12421 tgtttctaca atgattttgt cttctgttat ttcttcaaaa aatagatgat ctgccaagtc
    12481 tacgctcgac atcaccattt ccaactcatg atacccatct tgccgtctat ataatacatc
    12541 cagtcctaaa tttatcttgg ctggcgcttt ttcaatcaat tccatcctct cacccattcg
    12601 aaaagtctaa gtcgcaagta ttctatcata gggaaaaata aaagtatagc ttatgtctgc
    12661 ctagtggttg attttgtcat cgtttcaaca gctttcacag aattttctct tcataatcca
    12721 aacaagttct agtgattctt ataattctgt gagcacttct tctgccaaac tcggaacatt
    12781 tcctttttct tttcctatca gactgagtag ctgcatggta gcaaatccga aattacttcc
    12841 tttcctataa gcaaaataac gtccttccca atgatcgaca tattttaatt tcttttcata
    12901 agcagactgg aaggaataga aaaaattacc ataattatat acgatatgca tgactttttc
    12961 ttgaaagaaa gaaaaatctg tttctccaac attagctaat ggagctaagc ctagattggc
    13021 ttccgagtag cccattttct cgtatacaat aaacagattg gctaacagat agtcagctaa
    13081 ttcctcagat tctttaggta agacccgcaa caaatcatat cccgcctgct tcttcgtcat
    13141 cggctgagcg gtgatgaagc caacgacttt ttgatcttta cggacaatac cgacaccgct
    13201 agataataca tatgatttat caaatcgtcc cacagagaag tatttttctc gtgcaccttg
    13261 aagccatttt tgtgaaactt catttacagc ttgatgtaat tcttccggca gttgatcgta
    13321 ccaagtaaaa tggtatcctt ctttcatcaa acgttgatat tcaagttgct gactcagccg
    13381 agacaagtct tctgttgcta gatcaacaat ccctgcttca cctactttcg tgaagtgaaa
    13441 acccaattca tgaagcatca ctacgtagct ttctgatatc ttataaaacg caagctgata
    13501 gcctaaacaa tctgcttgtt tcataaactg attcgttgct gcccgcatca ttttaggatt
    13561 gccaactgga tctcctaaaa caaagcattt gtttcctttg atctgataac caaaaacgac
    13621 ttgatcttgg tcgtcttctt ggtaataaaa ataactgtaa cctgacaagc gaagctgatg
    13681 gcttgtagct gtgcctccgt atgtttccaa taaacggtca aaacggtctt tttcgtactc
    13741 actgccaagc ttcgtagtat cttcagctaa atattgataa agcgccacta aagctagcaa
    13801 tgagatgccc aaaccaataa gccctgagaa ccacacatca tctgaaggaa acaaaataaa
    13861 atgatttcct gttattcgac cgactaaaaa gcgtccgctg tgatagcctg caattgcgta
    13921 aacgataaac aaaaagccga acaagctagc atcaaagatt atagctcccc aagaataaac
    13981 gaattttgtt cgataaaatt cttttctgga taaccacaca gctaacagaa tcaagacata
    14041 taccaatatc aactgccaag ataacgtacg tgtgattgta tttaaaatac caaaagatag
    14101 taaagcaatc gtaggcagaa atgccttttt gacttttact gaaagtgctc tagcaaggcc
    14161 gagtaataaa aagccaacca atagattcac tgtctgatct aaaaaattga atgagaacgg
    14221 caataatact tgaaatagcc gactgattgc agacagatta gtgattgttg atagaagtac
    14281 catcatgatc cccgcaaaat agacagcact tacgagcacg atatgcgcaa ccttttggaa
    14341 aaacagtcgc ggaatgttat ctaaaaatcg attgattttg actcctgtat gtgtgatgaa
    14401 caatagaagt cccgtcataa aaggtagaac ataataaaac aaccgataat ataatagcca
    14461 aactactgct acatcttgcc gaacaggcaa ttgactcatt cctaagatca tcaaaacgtc
    14521 aaaagtcccc attccacctg ggaccatcgt cagcattcct atcaatgtag caatcatgaa
    14581 cataggatag atcgaaagca tcgaaatatc tattctcatc aacttgccga tgatcaaaaa
    14641 taccgcaagg gctcccgtcc attgtccaaa ggatgccagt agcagaccaa gcaagccttt
    14701 tggataaaac tcgaagaaca atgtctttct ctttagataa gcaaaaaaga aaatgactgg
    14761 tgctaaaaaa ctaccgccga aaagccagat ccaatagctt cgaaaaatac tttctgactg
    14821 aataaaaaag acatcaataa atgtaagaaa cgaccataca gacaaaccag tcagcataaa
    14881 tagtgcgact tttgatacag tggctaaaac catttttcta tttgtctgct ttccataaaa
    14941 actagcccgc agacttgctc ctaccacacc accaaaaccg gcgagattgt tgatcgtgtt
    15001 tgttacccac gcagcaagaa gaaactcttt tctttccatt tttggttttc cttgtttttc
    15061 taagactctg atcgtcaccc aatcatacaa caacatcgga gtgacaccca gcagtccagc
    15121 cagaatcatg agcaggatcg tcatgcggct ttgttgtccc atcctttgcc aaatatcttg
    15181 ccaactcatg ccattagcaa tatttgcgac ttgatttgcc acaaagacta acacggagcc
    15241 gaaaaaaatc agttttaaaa tcagactatg ttcctttatc cattgcagca tcaagtatcg
    15301 tttatttttc acattttccc attcctaact tgtatacttt tgtgtcatac cccaatgtta
    15361 tcttatttat tttaattttt ccactttaga cctgttcttt gcttgcgatg atagaaaaag
    15421 aaagatatcc taatgctaaa ggagaggata acatgaaagt aggatttatc ggcacaggga
    15481 atatggcaca agctattatt gatggtttat taaaaaaagg aacagtctcg aaagaagagg
    15541 tgttcgtttc cagtggacat tttgaaaatg cacaaaaatt tgctgctgaa actggcgtcc
    15601 atgcatgcaa aagtaatcag gaagttgcat cacaatcaga tatcgttctt ttagccgtga
    15661 aaccaaaaat cattgaaaaa gtattggaag aactaagaga atatagccag aaagtcttat
    15721 tcatttctat tgcttcagga aaatcattaa cagatttaga aacagcgctt gaagatcctc
    15781 aggcctccat cgtacgtgtg atgccgaatg tcaatgtcag cgtaggagca ggcgtttctg
    15841 cgatttgcaa aaatgaagct gccacggagg aacagcttca gcaagctacg atgatttttg
    15901 aagcaatcgg cagcgtctat cctttagcag aatcagattt cagtacattc attggccttg
    15961 ctggcagctc acccgcattc gtttacatgc tgatcgatgc gatgggacgg actggtgtac
    16021 tgaatggttt gtccaaacag acagccactg agattgctgc aaaagcaatt atgggttctt
    16081 gtcaaaaatt cctttcaagt gataaaaatc catgggaact tgtagaccaa gtttcttctc
    16141 ctggcggtac aactgttgca ggtgtagttg ccttagaaga agcaggattc atcccagcaa
    16201 tcatcaaagg aatcaatacg acgatcgaga aagatcttga gatgttgaat aaaaaataat
    16261 gatagcaatg ttttttcgtg ccttacaaaa aaagaagagc tgtggctttt gccgcggctc
    16321 ttcttttgta ttttttatta tttagcataa tcagttgcac gagtttcccg aataacgatt
    16381 actttgatgt gtccaggata atccagttct tcttcgattc gtttacgaat atcacgtact
    16441 aaacgaacag cgtctaaatc cgagatttct tctggcttga ccattacccg aacttcgcgt
    16501 ccagcttgaa ctgcgtaact tgattctaca ccggcgaagc tgttcgaaat attttccaga
    16561 cttcttaaac gacggatgta gttttctaat gattcacttc gcgcaccagg tcttgctgct
    16621 gagagcgcat ctgctgcagc tacaaggaca gagataacag aagtagcttc cacatctcca
    16681 tgatgagaag cgatcgcgtt gattactact gggttttctt tgtacttggc agctaattcc
    16741 gcaccgatct caacgtgaga tccttcaatc tcatggtcaa gtgctttccc aatatcatgg
    16801 agcaacccgg cacgttttgc taattggata tcttcgccaa gctctgctgc taagatacca
    16861 gctaattttg caacctcgac cgaatgcttc aagacgtttt gtccataact agttctgaat
    16921 cgcagacgtc cgatgatctt gattagatct ggatgaagtg tatgagcacc gacttcaaac
    16981 gctgcctctt ccccgtattc gcgaatacgt tcatccattt ctttacgaga tttctcgacc
    17041 atttcttcga tacgcgctgg atggattcgt ccatcttgta tcagtttttc caaggtcatc
    17101 cgtgcgattt ctcttcggat tggatcgaat ccggaaagaa caactgcttc cggtgtatca
    17161 tcgatgatta aatcgatacc agtcagcgtc tcaagcgttc gaatattacg accttctcgt
    17221 ccaatgatac gacctttcat ttcatcattc ggaagggtaa cgactgaaac agtcgtttct
    17281 gaaacttgat ctgctgcgca gcgttgaatc gctaatgata ataagttttt cgctttgcga
    17341 tctgcttctt ctttggcacg ctgttcagat tcttttacca ttagagttaa ctcatgattc
    17401 agctcttctt cagtcgattt catgatgaca tctcgtgcgt cctcttttga taaaccagca
    17461 attttttcta gttctttttg ttgatcttca atcatttttt caacgtcttt ttctcgctct
    17521 tcaattaatt gctgttttga actaagtgct tcttctttac tttcaagtga gttctcgcgt
    17581 ttttctaacg agtcatcttt acgattcagc gtttgttcgc gttgaatcaa acgattctct
    17641 tgagatttta attctaactt actttctctc agctcacttt caacttcaga acggtatttc
    17701 tgattttctt ccttagcttc taacaatgct tcttttttta gagtttctgc ttcttttttt
    17761 gcactatcga tgattccagc agctgatgat tgtgcaccag ctatttcttt ctcgtgacgt
    17821 gactttgcga ccataaaccc taaaccaaga ccgacaatta aaccgatgat agcgaggaga
    17881 atgttgaata ccataaaatc cacctccata ctatcttttt catttttatc atctatacag
    17941 cttctatgat aaattattct aaactcgtca atatgcatct tcgcatatat gtgtacaaaa
    18001 aacatgcaca actttattct aatgtttgta ccccgtagtg tcaactttaa ataaacaaag
    18061 aaacggcttt ctacttattc attaaacgat ggtttttaaa ataaatgaca ctagtttcat
    18121 ataggtaaac ctttaaattg agaaactttt ctattaaatt attctttgta gatgaacaga
    18181 tatttttatt ttatgtaccc actcgtataa ttaaataact cacgatttct ttattcaata
    18241 aaaaaacggc aggtcaagga gagtacctac tcttcagacc agccgttttt gtttatcata
    18301 atttttattc ttctactaaa ggcaattctt cttgtccttt ttcatcttct gggacagcga
    18361 cttcttcacc aataccataa gctgctctaa ctagagcaga aacttctgcc atcatttcag
    18421 gatgattagc catatagatt ttagcgtttt cccgtccttg accaatccga tcttctttat
    18481 aagaatacca agcaccgctt ttatcaacaa tgtctttttc tactgccatg tctagaagtt
    18541 ctccttcttg tgagatccct aaaccataca tgacatctac ttcagcgatt ttgaaaggag
    18601 gtgctacttt gttttttacg actttgatct ttgtacggtt accaacaata tctgtacctt
    18661 gtttcaattg ttctgcacga cgtacttcca aacggatcgt tgcgtagaat ttcaatgcgc
    18721 gtcctccagg agtgatttct ggattcccaa acatcacgcc tactttttca cggatttggt
    18781 tgatgaaaat agcgattgtt tttgttttgt tgatcgaacc agagagttta cgcaatgctt
    18841 gagacatcaa acgtgcttgt aacccgacat gtgagtcacc catttcgccg tcgatttctg
    18901 ctcgtggaac taaagcagca actgaatcga ctactacgat atctacagcc ccacttgata
    18961 ctaaagcatc agcgatctct agaccttgtt ctcctgtgtc aggctgtgaa agaagtagtt
    19021 catcgatatt cacacctaat ttttgtgcat attgcggatc taacgcatgc tcagcatcaa
    19081 tgaaagcggc cgttccgcca tttttttgta cttctgcaat agcgtgtagt gcaactgttg
    19141 ttttacctga actttcaggt ccatatactt cgatgatacg tccacggggg taaccgccga
    19201 cacctaaagc gacatctaac gcaagagagc cacttggaat tgtagagatt tgttggtcga
    19261 ttttttcgcc caatttcata atagagcctt taccatagct cttttcaatt tttttcagtg
    19321 cagcatctaa ggctgcttta cgatcatctg ccaatacgat aatcctcctt atatttacaa
    19381 atcagagcaa catttcatta tccttatcat atctttttta gtgaaaaaaa gcaagaaaaa
    19441 accgaacaaa tattcgcatt tatcattttc ttaaaagctg ttttctcaaa agatcaaatc
    19501 cttgcataac cgcattatat ctgatagcag cacgatctct ggcaaagtga tatttttccg
    19561 aaaccacgcc gtctttagat gaaatagcga tccatactgt tcctgcagat tgaccttcta
    19621 acgtgtccgg tccagccact ccggtgaaag ctacactgta atctgttctt gctatctcac
    19681 gtgcttgaat ggccatctgc tccacacatt ctttgctgac tgttccatat tctgctaata
    19741 gctccggatc aatctccaga aaaccagctt ttgtttggag cgagtaggta acgaatccgc
    19801 ctggaaatac ttcagataca ccagcaatgt cgcctaatgc ggcttggaag gcgccggctg
    19861 tcaaactttc cgctgctgtt acagtctgct tgttttcttt cagtagttcc actacgactt
    19921 ttgctagcga attatcatcg ccgtatccat aaaaatattc ccctactcgt tcttggattt
    19981 tttcttctaa tgctaaaaga gcttgattcc ctgcctgaac atcatttgtt ttcactgtca
    20041 gtcgtaatgt cacttcattt ggtttggcat atggtgcgat cgttggattg atctgtgtct
    20101 caatcagatc ttttagctca gtgaccagtc gcgattcacc aatcccataa aagcgcaaaa
    20161 ctttagaaat tagtttttct tcagaaggaa aacgttcctc tagtaaagga cgtacttgtt
    20221 ccacaaacat tggtttcaac tcattaggcg gaccgggaag aaggatatac gcatgtgtat
    20281 ctgtttgata aaaagtccct aaagcaagcc ctgtacgatt tggtagagga accccgcctt
    20341 cgataatctg ggactgttgc agattgtttt tggtcatttt tcgatgggtt gtttcaaaat
    20401 atgccaataa ttttttgtat ccttccgtat tttgtatgag agacttaccg aggtgagccg
    20461 cagttgcttc ttttgtcagg tcatcttctg tcggtcctaa tccgccacat aagagtatga
    20521 gttcacttct tgtttcagct agagcaatca actcttctaa acgctgctga ttatctccta
    20581 caactgtttg ataataaact tcgataccta gatcagctag ctgttctgac aagaaagtgg
    20641 cattcgtatt cacgacttgt cctagtaaaa gttctgttcc gacagctatt atttctgctt
    20701 tcattacttc ccgctccctt atatagtata cgctgtattt ttatattttt ttatttaaaa
    20761 agagggcaag gagctgtgac aaaaatcttg tcacagctcc ttgttccaaa taaacagtgt
    20821 tctcctgcca aaacctcggt cataagtcac aatatacata aaacatgaaa agctgttttt
    20881 tgaaattatc ccttgtgact cagagttaga cggcaggctc acaacctctc cactaaacga
    20941 tacttacatt gatcctttga acacaccgct gtttttgatg aagtaatcca cacctgaata
    21001 gatagtaaag atcagacaag cataaagcat gatttgatct actggaatac cgatcaggct
    21061 gaatgggata ttattgataa acagcaagat aatagcaacc atttgtgtag ccgtcttgac
    21121 ttttcccggc caagctgcag ccatgacttc tccatgttcg acaagtagta aacgcaagcc
    21181 tgtgacggct aattcacgac agacaatgat cgctactacc caaccagggg cctttccttg
    21241 gtcaaccaac atgataaaag cagtcataac tagcatttta tctgccaacg ggtccgcaaa
    21301 cttgccaaaa ttagtgacaa ggcctcgcgc acgggcaatt tttccatcta accagtctgt
    21361 gatactagct aaagcaaaaa taactgcacc tactagctgt gtgacagcca gtgtggtgtc
    21421 tcctacgtta aattgtcccc aatctaaagg taaacctaca accaaaatga aaatcgggat
    21481 catacaaatt ctaagtacag ttaatttatt tggtaaattc acactatcga ctcctttctt
    21541 ccctattcta cgtgactatc agcgaagttt ccaccgatat tatttacttt tccaaatgaa
    21601 tttattcaaa ggagtatttt tattgaaatt gatctttttg aattaacgaa gaaggaccgc
    21661 gacacagatt tgtcacgatc cttctttttt atacctacaa gtaaacagat gcgtaaacta
    21721 atttatacga tcattctgcg tattgaagag taaggttcac attttttgga ctctgattgt
    21781 tttcccctgg attaactggt acggattctc cattcgcttt gatcgttgca ttgcttgctg
    21841 caccaatcgt gatggtcgca tttgttgctg tttccggtaa cacggtactc tgtgtttcat
    21901 ttgctgccag tgtcccttga taaacatagg cattgtctac tagcacacct aaccatacac
    21961 gattgacagc agtaaattca agggttacag gcttggtagc gtctgtgata tttactgcga
    22021 tggcactgcc agaatcttct cctgtagcta ttgccatttt cttttcttca cttgattttg
    22081 ttgttgattc tactgtagaa gactctttgg tctgcgtgct ttgctctgag gaagaggact
    22141 cctcgactga tccttctact ttaagcgaag aagctgtgtc tccgattatt ggatcagctt
    22201 gacgatcttg ccaagtcata tagcccacga caacgacaat cgccaaagca accaatccta
    22261 ataaaatgac aggaagactt gtccaaaagc gacttggatg cgattcttcc tgatgcattg
    22321 cttttctaga agtacttact gtttcaggct gcggacgttc agggaccgat cctgtcaatt
    22381 tgcttttccc atcaaaaaca tcgactaaat ggtctccatc ttctcctaca gcttcagcgt
    22441 attgccgaat aaatgcccgc acgtaaaatt taccaggcaa ttggtcaaaa tcatcattgt
    22501 cgattgcttc caaataacgt ttttgaattt ttgtaatctg ctgtaattca tctaaagata
    22561 tttttttatt caggcgtgct tgccgtaatt tttctccgat ggtttcaaaa gccactcgtt
    22621 catcttctcc agtctgtttg attctccgaa gcatctgctg ttgcaacgaa agacgttatg
    22681 tttgggtgct gtgacaaaag tcatgtcaca gctccttttt tccgaataaa cattgttctc
    22741 ctgccaactc ctcggtcaca agtcacaata tccaataaat ataagaagct gttttttgaa
    22801 cttgttcctt gtgactcgga gttaaacggc aggctcacga cctctttctt aaacggtgtt
    22861 caatcagctg ttcctcggta ttagctcaaa aaccggcaaa atataaggag atatttttcc
    22921 gtatgtttct ctaatactca ggtcaaaacg ctgatttcac aacctcttcc ttaaacggtg
    22981 ttcaaaagct tgcatctgcg gtaataagtc caaccaagtt aaaaacatta agaagctgtt
    23041 tttacttggc tgttcttatt acttgatgca gggcagcttt ttcacaacct cttggtacac
    23101 ggtgttccag aagtagcttc ttcggcaata agccgaaata tcacaaaaat ttgagaagca
    23161 attttcgtaa attccttctt atttcttgaa gctgaccact tctgtcacaa cctctttgat
    23221 tacttcgttt gattttattt taatataagt tgattaaaag agagcatgat ttgttttatt
    23281 ttctcactaa tttttccaac acaactaaga ataccataaa agctgatttt ggaggaggtt
    23341 cctactacaa gtctaaaacg aaatttaaga cttttcctca taaatactgg tttattttgg
    23401 tctcatgtaa aactcgctga aggcctcttc acttataaat gcttccccag ctgccagtac
    23461 gtctttcatt tggatcgaat cgatgatttc aggaagatca aataaagttc gatcgccaaa
    23521 taaactttgc gtaaattgat tggcaatata ttcgatcgaa tttaatgatt ggaaatattg
    23581 tccaagcatt ttcttcttca gcaaatcgag atttgtttct gacacttccg gatcatcagc
    23641 gaatccaaga atgatttctt tgactttttc tgctgctttc tctggttcgt ccgtatctcc
    23701 gctgaagtcc gcaaagtgaa attcacgatc caagctgaat tcaaaaccaa agctgtcatc
    23761 gataattcct tgattgtaca tcgctagata gtttcgagaa gtattgccta aaatcatttg
    23821 gaacaacaga ttgattgctg ttttatagcg taacagttct gttccttctt gcggcaatgt
    23881 gtctaatcct ttaataccaa gtacaaattt atctcgtgta atggctgctt ccaatgcact
    23941 ttgtttgatg atttcttttg tgttttcagg gaaataacgt acaatttctt gctttggagg
    24001 gaaatttttt gcttcttggt tttcccgaat aagtttcatc aatttctcag gctccatctt
    24061 accaactaca aataaaacca tattgcttgg ctgataaaac gtccgatagc acgtatacaa
    24121 gtcttgagct gtgattttgt cgatactttc aaccgtgccc gcaatatcga tatgcaatgg
    24181 gtgtgtagga tacaagttat ttagtatgcc aaaaaacatc cgccagttag ggtcgtcttc
    24241 atacatttgg atttcctgac cgatgattcc tttttccttg tttacagttt cttctgtgaa
    24301 gtaaggtgct tgtacaaaat cgatcagagt cgtcagattc ttttctacct gatccgtcgt
    24361 agaaaacaga tagctggttt tcgtaaaact tgtgaaagca ttggcggaag ctccttgttt
    24421 cccaaataat tgaaagacat caccatcttc tttttcaaac aacttatgtt ctaaaaaatg
    24481 ggcaattcca tctggaactt tcaccttttc tttttcacca tagggaataa attcgttatc
    24541 gatcgaacca taattcgtac tgaacaaacc atatgtcttg tgatagtcat ttttaggcaa
    24601 caaatacacg gtcaaaccgt ttggcagtac ttcatgataa agtgtttcat tgatttgctc
    24661 atattctgtt ttattcattt gcatttcctc ctgctaaaaa gaagattgcc tgcaattcga
    24721 tttgctcagc tacttgttgt atctctttga tcgttacgct ctccatacgt ttcaaccatt
    24781 cttcatcaga taattttgtt tccggcagcc agctgtccaa aaaagaagct tcgattgccg
    24841 cttgcggaga gtctagagaa agcagatatt ggtttctcag cattgctttt gtctgagaca
    24901 gttccaactc tgttatttca ccatttcgca aactttctaa ttgctcgtga atcagatgaa
    24961 gtacttgatt tcggttcttt tcatcgatac cggtttggac actcatgaat cctcggaacg
    25021 tatccacgct actagaggca taataagcta gactttcttt ctctctgaca ttcatgaaaa
    25081 gtttagagtg aggaaaaccg ccaaataaac cgttaaagac cattagcgca aaacgttctg
    25141 gttcatcgta atacacattt gtctgataag ctaggttcag ctttgcttga acgattggct
    25201 cacgtacttg tcgttccttc acgatattca cttgaggttg ggtataaaac agatctggat
    25261 aaactgtttc ccgcgactca aatggtaatt gcccaactgc ttcagctgct ttgtccggat
    25321 caacatcgcc gacaacaaaa atgtcgattt gatcatttgc catcatttct tgatagtagg
    25381 acgctagcga actagcagtg atcttgtcca aatcttcgac tacgcccaac cctgggatct
    25441 tttgttccgg gctgttttca aaataaagtt cttgcaaggc ataggaagca aaagtttgtt
    25501 tatcttcctt caaactttcc aaatatagac gcagattgtt cttttccaag tcaaacgtca
    25561 actgatcaaa ctgatgattt ttaatatttg gataaaataa aacctctttt aaaaaatcta
    25621 ccgcttgaga aaaaaggttt ggatcattga catattcacc attcacaaaa ctgatccctg
    25681 cgtttagcca atgtaaattt cctttttttc taactgataa tccaaagctt gcgccataaa
    25741 gctctgcaag ttgcgcactt aactttgtct gatccggata attcaaacta tttgtttcca
    25801 acatgctgct gagaagtgaa cgtttcgtga tgacttcttg ttgcagacgc gcagtaaaac
    25861 ggataaaaat ccggatcgtt ttgtattgtt ttgttggtaa gacatgaaga ttcacgcctt
    25921 ctgccaattg atacaccata tttatatgct ccttttcaca gttgattgcc cgcttactct
    25981 tttaatgggt caacctgcct tttttactta ttcctctgct tgaaatttat aagttcaggc
    26041 aattcgccgt tttttctaaa tgatgttaca ctttatagta tagcatagat gttttttatc
    26101 aaaagaaaca gacggctaaa agcgtatatt gtttttttat tttttatttt tcgatatact
    26161 aaagacaaat aaaagaaggg agggtcattc atgatcaaag aattcaaaga gttcatcatg
    26221 cgtggagatg tcttggatct tgctgtcggc gttgttattg gtagtgcgtt tacaagcatc
    26281 gtaaaccaag tggtgcaagg cttgatcaca ccactaatag gttggtttgt cgcaatgatc
    26341 acaggtactt ctgatttaga aggagcactt tcaattcttg actggtcgcc gacaaaaggc
    26401 gtcacatttg cgtttggtaa cgttattagt gctatcatta catttctgat cactggtttt
    26461 gtcttattct tagttgtcaa agcggcaaac cgtgcgaaga atttacgctc caaagaagag
    26521 caagtggaag tggaagaaac tcctactgca gaagattatc ttagtgacat acgcgatctt
    26581 cttgccaaac aagtggcaga agacaataca catccagtag agcaaacaaa tctttccgat
    26641 acttctaaat aataaagaat ctaaaaaaaa gaaagccgat tttcagtgtc ggctttcttt
    26701 ttttagattc ttaacttgct acttgttcct ttttcatgtc gatatgtgga atatcatctt
    26761 ccaaatacac atctgagatt gccttgaatc caaacgactc ataaaaagct tgtaggtatt
    26821 cttgtgcgcc gatcacgatt ggtttttctg gaaaattttt ctggatcatg ttaatcgttt
    26881 cttgaacaat ctttcttcct aaaccatctt tacggttgtc ctgatgaaca aggacacgtc
    26941 caaaatggat actctccgct tcttcatata ctcgcgtgta ggcaaggatc ttcccatcag
    27001 tatcttgaaa aaacgtatgc caagcttgtc catcaatgtc atcaacttct tgataaggac
    27061 actgttgttc cacaacaaaa actgcgattc gttctttgac gatcgcgtaa aactctgctg
    27121 ttgacaattc ttcaaatttc tttacctgat attccactaa gcaaacgccc cctgcttttt
    27181 tattcttagc ataccgattc gcacacaaaa aagcaaacga accttacgaa tc
//
LOCUS       DADQDV010000035        27185 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.035, whole genome shotgun sequence.
ACCESSION   DADQDV010000035 DADQDV010000000
VERSION     DADQDV010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 27185)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27185)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27185
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.035"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(84..785)
                     /locus_tag="J8S10_001565"
                     /pseudo
     CDS             complement(84..785)
                     /locus_tag="J8S10_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354515.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
     gene            complement(785..1567)
                     /locus_tag="J8S10_001566"
     CDS             complement(785..1567)
                     /locus_tag="J8S10_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630152.1"
                     /translation="MLDFQSKPNIFEEMSYEEAVKWLLRQAAIHYDGSDHDAHVLATE
                     SNAGFATPETVMQARGRWLRDYKLPQKYPNILDIPPGKYATKAGWGADNPDGIEDDSF
                     VEMMVFADHDSRKLIVAFARYSGEIYIKMTHNSEPVEGYNSLGWRRVYTTSVLFEGEL
                     RKGQSVNLPDDTFRYQTLRIHYTDGDGDFVEEVKRQRYARITKANLWNGDAGVTFIEF
                     ELTIEARKITMSNGRALDISSGNVSNPAMSNNVKITKIEGVK"
     gene            complement(1584..3341)
                     /locus_tag="J8S10_001567"
     CDS             complement(1584..3341)
                     /locus_tag="J8S10_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HAZ9630153.1"
                     /translation="MQETTSISKGGIVMAETQHKMVLSTTEPNNGINLVRIRQGDVLT
                     QKFVVEVVEHGKLKTFEGLVPFFINTTKFGENQPVEQKVQEYSPAQARLVYTLSEPDW
                     QWGGENTAHFSFRSLNGDGTWSEQFSTQDFTYRVISGISRSQLRDSGYVWTFEDLLRK
                     FKDYMDQGKNDWEQWLEDNREILENIDPGGMIINILNEAKGDYESLADRLNQKYQVPV
                     GSSQIRETTRFFDYDTMKYVDLVPRNLNTVVNSVNNSKFNFSFITDIHADNHNLRIDG
                     VGYKDASYLRHWRAIPQFQKLGNKTDVMIYGGDNIDGGLGSLGSDIGIIDEWSARHSM
                     LGTLKRFTNAAVAGQEKPVIICKGNHDACFDPAWRKRKGMLCNADFEEYWNGLYGGVL
                     FPDKNAAIYRFDTCDFYEGGTGDKYVDGYSDTAPGAFSAKQINAFGEWLVNVPRNYHV
                     ALVGHTPLGLSKFPVRNENMISTLIEGFKSGSPVTIDWSKLGQPNDGSFGGLKTFAMN
                     TKGAGVVVGYFCGHWHEQVEGAFGTVKMILCDVGFSHTASQVDTPDELAFYKIEVDTA
                     TRKVTSKGVGRARDFTYNY"
     gene            complement(3316..6147)
                     /locus_tag="J8S10_001568"
     CDS             complement(3316..6147)
                     /locus_tag="J8S10_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HAZ9630154.1"
                     /translation="MSETVYFFDHLQKLIKRKNTRSLIEVSQEKEISSDKSDLMKDTL
                     YVTTKYDKEIEDARYMAIRENESSFSLYRITKVSDPFETLEFTGLGFATNELDAYIIK
                     DIRPSGQPLKNVLDRLIEFTEGNWRVGHVEAMLPTVTATFYYVSVKEALKELQTLGME
                     FVFRCSLNSDGIKDKWIEVYEQIGEESNTRFVYGSKALTVVREIDRSSISTSMIGRGR
                     GEEVGDGYGRRIEFTDVEWKKSNGDPLDKPKGQNWLEDPESTQKYGIPQKDGSMRKRE
                     TVVVFDDIDDPTDLLKNTYSTLIDSARPLVQFKAEVTGGDVIGNTVTIHRYDKGYHYK
                     TRIYKTTFNRLTGQTNIELGDNLTQDVRKQTASIVNNINSLESSKMTFYESTEIGKYQ
                     DDIMRGAGDNGGSIYWVNGIEAGVSDSREIYETVYMDGPNIPRSRFFMVQNNSGISFK
                     QCKKGEWQTIQDVHNGDSTTAWTLDGTFNANFIRAGILSGILVQGVALKTFDDKDFQL
                     VAEGGELSFEKQVKSTGLDDVHGERLGSIVSTYGSKGINGFAVWKEPNYIFSINAGDG
                     GDRGNPIFQIPADVTADKRKYNLYGDGNFSEGNITIDGRLDVKELYVNGTKIDTNGGG
                     NSGGNDNGWNGQYPPEVTTDRDKRYWQIWATAIGAGFTQQAAAALLGNAQGESDANPT
                     ADEGNGAPGFGYGVWQWTDSSGATSGRVYMINLMTKAGISDDPDTITAQFKLLMWHAP
                     NGQWIATSAYPYTWTQFMNLTDINTAAQAFVANFERPRDPHPERTAWSQEWYDKFKDL
                     EIPVSKGYMKPIADPITVTSEFGWRTSPITGAQEFHNGIDLVNGNPNTPIFASADGEV
                     IVAGDANYFDWYGNWTVIKHADGMYTGYAHQSRVDVSKGQKVTAGQQIGLMGTTGPST
                     GEHLHFQFMDEFYPSSSGHFHNARDYIDF"
     gene            complement(6144..6911)
                     /locus_tag="J8S10_001569"
     CDS             complement(6144..6911)
                     /locus_tag="J8S10_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAZ9630155.1"
                     /translation="MYSFKDTTINLTSSKRFLPTSAMMYDGMYLEDLIDGYQTLTVEG
                     REMLSVEVEQQEIQIGSIITNQKIPSRTLKITYKLEDRDPEKLQFKFKELLNYLYRNE
                     DVEIRFHDELDYYYYGRYTSTDTVPGDSNSIISSFNVFCADPLKYTKECVSDGYIGNP
                     IQFPITPRKIEVTLSMNNSIKITNGEQNITITDAAIKTGDVLVFDFSDEQVTVNGEDC
                     TSMIDLESDFENFYLKQGQKITSNNGKLKIFYRGATI"
     gene            complement(6944..10063)
                     /locus_tag="J8S10_001570"
     CDS             complement(6944..10063)
                     /locus_tag="J8S10_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HAZ9630156.1"
                     /translation="MEQFSVEALLKATDSGFVKTFKDAQDAVKTFEKNSNSMTTAVGK
                     VMQGTGAAMTKYITTPLIGVGVAAAKVGGDFEAQMSRVKAISGATGDTFEQMKQQAID
                     LGAKTAFSAKESAAGMENLASAGFSAQEIMKAMPGLLDLAAVSGGDVALASENTATAL
                     RGFGLEASEAGHVADVFARAAADTNAEVGDMGEALKYVAPVANSMGISLEETAAAIGI
                     MSDAGIKGSQAGTTLRGALSRLARPTKAMQDTMDNLGVSFYDADGKMKPLKTQVELLK
                     KAFEGLTPEQQQNALVTLYGQESLSGMMALIDKGPDSLGKLTKSLKDSDGAADDMART
                     MQDNMNSSIEQMFGAFESAAIVIQKILAPSIKKVADAISGLVEKFVSAPESTQKLVVA
                     IGAIVAAIGPLIFMIGSVIIWINRVKVAFKALSESSKLFSGLSKAMGLLTNPVFLVIA
                     AVALLVVGFIYLWNTSEDFRNFWIGLWEGIKSAVSSAVEWIQNAWKSTGEWFNNLWKS
                     IKEGADNVWTTVQEAPGKAADWIKNKWTGTKEFFSNLWSSIANSASEIWNSLKEGVIS
                     VIDDLVSSAGEKWEGFKNTISTAWKTITSKIKSGFDFILKYIGPFVSSFSDVFSNIVK
                     AITSIFAEVKNIIVNAWEIIKSLIAAPLLFIIDLITGDFEQMKEDLDLIWNTLVQSVV
                     NIWTSVKNIFTEYIGAIVNSAVSLWTGFIQSISNIWNEVVYQATMIWIDLKLFFTNLW
                     IDIKYSAIQMWINLKFSIIQTWIDTKYGAIELWNNLKQWFFQTVNNIVQTLIKSWNSL
                     KQGTIDLFNNTVQGAKDIWTSFKSWIGDLITGTKDNIIQGWENLKQGTIDTFNNLVNG
                     AQEAWDNLVNAVSDTVDRVTGWFDNLKNIDLLAAGKAIMDSFLEGLQNAWKSVQDFVG
                     GIGDWIREHKGPIQYDRKLLIPAGQAIMNGLNKGLTGGFNDVQNTVGSMADFIAELFN
                     ANSDVDIAANLKNANKNIGAQVEHKINMGGSTKPAVFKINLGRQSFRLFMDDISQAMG
                     EGADINLEF"
     gene            complement(10080..10367)
                     /locus_tag="J8S10_001571"
     CDS             complement(10080..10367)
                     /locus_tag="J8S10_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630157.1"
                     /translation="MTNISDIERMTLYEYNIRMTAAQLSWLDKEKLIHELAWANQQVQ
                     AEKKVGKKTVPVYRSFEEFFNYQKIEDSIMGVSELSKQDKKFQSLLTKANS"
     gene            complement(10421..10789)
                     /locus_tag="J8S10_001572"
     CDS             complement(10421..10789)
                     /locus_tag="J8S10_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630158.1"
                     /translation="MKLKIKGKEYSFKFGTKFVRELDKVMPFVDGNMEFGMGLSAKVL
                     PELRSYNVNTLSRVLEIANRTEDESITLDELDDYIDEVKDIEKLFDEVLKELAESNAG
                     KLAVRNLNQKLKEAEKQQVE"
     gene            complement(10835..11347)
                     /locus_tag="J8S10_001573"
     CDS             complement(10835..11347)
                     /locus_tag="J8S10_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
                     /protein_id="HAZ9630159.1"
                     /translation="MEALKGIDVILLYRLLKKETQEAAWKMAFQTEHENGLSRDSDST
                     VTKDGNVQSLSPVEYDFSATSIVAKGDSHVDEMKQALLNGDIIEIWEINKAEQGTDDN
                     ANKYKATYYQAYVSEFTPSAAAEDNVELSLSFAVNGVGQDGYATLTEDQADVVQYAFK
                     DTVKATSTGA"
     gene            complement(11358..11750)
                     /locus_tag="J8S10_001574"
     CDS             complement(11358..11750)
                     /locus_tag="J8S10_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HAZ9630160.1"
                     /translation="MIKTRDQSIFDELFKISQNKLGYKTYDYKTLEDVGYPFVEFENT
                     QTIHEVNKTDIKGSVIVVLSVWGLQKKRKQLSDMASALFNEARLIEATEGYYWALNYQ
                     ASGIQVMDDTTTNTPLKRAVVTLEFRIR"
     gene            complement(11750..12088)
                     /locus_tag="J8S10_001575"
     CDS             complement(11750..12088)
                     /locus_tag="J8S10_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HAZ9630161.1"
                     /translation="MKAQLEYKGIDQLMRHLKKAATLNDVQKVVKSNTAEMTERMQKG
                     APVDTGYLRRSINMNLLEAGLTGIVGPTADYAPYVEYGTRFMSAQPYVRPAFNYQKVK
                     FMAEMKALVK"
     gene            complement(12072..12398)
                     /locus_tag="J8S10_001576"
     CDS             complement(12072..12398)
                     /locus_tag="J8S10_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630162.1"
                     /translation="MRFTDEIIFVKRSSDSKYDPDLGEWVEGKPERTRTEANVTDIGT
                     DRSVTIFGSVEEGAKVIRTQPLFSIPTFDYIEIEGKTWQQKTARNPAYRNSLIVQEVV
                     LDEGTT"
     gene            complement(12395..12724)
                     /locus_tag="J8S10_001577"
     CDS             complement(12395..12724)
                     /locus_tag="J8S10_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HAZ9630163.1"
                     /translation="MMIADDIKKLLKGTIDEKLEVIERRTNERMKTLLNTQEVPKEFE
                     TVVYEVSLKRFNRIGQEGMQSYSQEGLSMAFPDSDFSEYQNEIDEFKRKDQEELYKPK
                     RGRFKFV"
     gene            complement(12736..12999)
                     /locus_tag="J8S10_001578"
     CDS             complement(12736..12999)
                     /locus_tag="J8S10_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630164.1"
                     /translation="MPNQKTWTGKVGDTKTFTISAVPADASDAAAVVAATTATSSDGA
                     IATVTKNENGGFDGTIAAEGSATFTFTSGEFTTSINVTGQPAS"
     gene            complement(13017..13940)
                     /locus_tag="J8S10_001579"
     CDS             complement(13017..13940)
                     /locus_tag="J8S10_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HAZ9630165.1"
                     /translation="MKKKQLLPMNLQMFAQTWDPDNVLVYETKEGKIPDKYNTLILSE
                     VMENSKIMQLAKYEEMTDKEKKFEYFAEGPGAYWVGEGEKIKTSKPKWMQATMTAKKL
                     GVILPVSREYLNYKLSDFFEEMQPKIAEAFYKKFDAAALLNKENPFPQSLDGSVISAG
                     NVVEGGLTYDNILALEDKLAENEFEPNAFISNRKNRTELRSAAQTVGSNVEFIYDRST
                     NTIDGLPVVDLKSLDKGTLYAGDFNYMFYGIPYNISFKISEEAQLSTLTNEDGTPVNL
                     FEQELIALRATMDVGFMIVKDEAFGKISPKA"
     gene            complement(13953..14555)
                     /locus_tag="J8S10_001580"
     CDS             complement(13953..14555)
                     /locus_tag="J8S10_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HAZ9630166.1"
                     /translation="MKKRLFMPMNLQFFSEPGDGGSGDEGQQGNLPAGSQETPPEAKE
                     ENNTGKTFSRDEVAKMIAAETNKAKAAWEKELAAKKEEAKKLAKMNAEEKLQHELEQK
                     EAEIAELKRGQALSEMTKEASKMLTDANLPHDDDLLGLIVSDDADATKQAVAVITNFA
                     SLIKRENARQTPPNEGGQFTASKNTKETVAKLAAKNRIIK"
     gene            complement(14682..15608)
                     /locus_tag="J8S10_001581"
     CDS             complement(14682..15608)
                     /locus_tag="J8S10_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HAZ9630167.1"
                     /translation="MNSQEYWIKREKEWQKQQIKDDKKRMAEIKSRMQYAQDAIQKEI
                     DAQWDSFSNGQKITRSEAMKRASEMDVKAFARKAKKYVKEKDFSPTANQELKLYNLTM
                     RVNRLELLKANIGLELISLFNELDKYFSNELTKAGLAELKRQAGILEMTIASSGYAKL
                     IELVINSSFLSDDVSFSDRLWMYQSELKSELDRLLVRSITMGKNPKQLASKLAEYLTA
                     EGRENTKFNTQRLMVTETTRVQVGIQERSYRDAGITQYIYIAEPTACKLCIPLNNQVF
                     DVADMQPGSNAPNMHPFCRCSTAPYIERISSR"
     gene            complement(15613..17112)
                     /locus_tag="J8S10_001582"
     CDS             complement(15613..17112)
                     /locus_tag="J8S10_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAZ9630168.1"
                     /translation="MDKVNEFEYGADIHYSNDVNTNYVKFSVDSNLHYRFSSAEDLLN
                     DLDTLAAMIKHHHEYQVKRLSVLDDYYKARNTNIMDNRRRREKEKADHRSAHNFGKVL
                     CTFDVGYNTGNPIKVQIEDTNQQKEIEEFNTNNDIDGLNAELWLDMDKYGRAYEIIYR
                     DSDDTDYVDLANVFETFVVYDTTVKREPILAVRYPKTRFNKDADKQYIQPIVYTKEKS
                     ITYDETTLTAIELKNPQDEPHEYKEVPITEYSPNRFRMGLYEDVLSLIDLYDAGQSDT
                     ANYMTDLNDALLVISGDIEAAGLSTEDAIKQKEANMLLLESGTDVNGNKTSVTAGYIY
                     KQYDVNGVEAYKYRVRKDIHEISMVPDLTDDNFSGVQSGEAMKYKLFGFEQMTATKQR
                     LFKKGLMRRYRLLFSLKSSISEMDNSDLKGLRVIFTPNLPKAILEELKSLVDAGAELS
                     QETILGLASFVPDVQAELKRVNKETQKQIGIFDSDGEEVINNKKDETGG"
     gene            complement(17125..18369)
                     /locus_tag="J8S10_001583"
     CDS             complement(17125..18369)
                     /locus_tag="J8S10_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HAZ9630169.1"
                     /translation="MALVDIYNPKQIDVLNKTIKNDWFITLLHGAKRSGKTKINNDLF
                     LFELRRVRKIADEEDIKEPMYILAGVSSATIQKNILQELYNMYSIEPKFDKHGNFKLF
                     GVKVVQAYTGNIGGVGAIRGMTAYGAYINEASLARQEVFAEIVSRCSGTGARILADTN
                     PDNPEHWLKKEYIDNSSKNIQSFHFELDDNTFLSERYRNNIKESTPSGMFYDRDIKGL
                     WVSAEGVVYRDFDASKHYIQSKDLPPLSNFYCGVDWGYEHWGSIVVIGETDDGTAYLI
                     EEHATQFEEIDYWVDVAKGIQERYGLRVPFYCDSARPEHVARFVREKINAKNAHKARL
                     SGVEEVAKRFKQDKLFICQDRVMKFRDEIYQYIWDKKKGEPIKEYDDVLDSVRYAIYT
                     HELLKKPKVNVNEKIKRIKRMF"
     gene            complement(18356..18889)
                     /locus_tag="J8S10_001584"
     CDS             complement(18356..18889)
                     /locus_tag="J8S10_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HAZ9630170.1"
                     /translation="MVNLTPKQKAFADEYIKNGGNATQAAIKAGYSKRSARVIGKENL
                     TKPNIIQYINERLNPIEKKRKLSAEDALNELIDIWQGEVQISVSKQIDRLEKNKVIKH
                     MQYEYTPDLESKLKALDLYLKYKSLLSQTQLEKAQTEIKLMQAKLEQLQINSERSTEE
                     KLDELLEKISGELDGTS"
     gene            complement(18916..19140)
                     /locus_tag="J8S10_001585"
     CDS             complement(18916..19140)
                     /locus_tag="J8S10_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630171.1"
                     /translation="MRNYWYVSLSNKYPQPNADDPIRVVQSVQIKKKYSIIEMTREAT
                     PKEIDKYNLRYCGHGYFSEQNIQTNIERYC"
     gene            complement(19147..19359)
                     /locus_tag="J8S10_001586"
     CDS             complement(19147..19359)
                     /locus_tag="J8S10_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630172.1"
                     /translation="MNENQLRELFKTNEANKTMEATFYETQKSLALIAKQAKYFYDQL
                     ILQGFNDAQAMEFMMRTFSASNQQKE"
     gene            19721..19900
                     /locus_tag="J8S10_001587"
     CDS             19721..19900
                     /locus_tag="J8S10_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegP family protein"
                     /protein_id="HAZ9630173.1"
                     /translation="MYFVIREATNGQYYFVIKSDNNEVVATSETYLTKYSAEQTINSI
                     KNGITKDSQVIDVTK"
     gene            complement(19893..20234)
                     /locus_tag="J8S10_001588"
     CDS             complement(19893..20234)
                     /locus_tag="J8S10_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630174.1"
                     /translation="MEVEQIKYQGMDRERLIDIIEQQRLELIQKEAVCKEYKKHLEQV
                     IEYHSVEKYRSVVQKNRATSPDPRQDVSISIKTPVFNSVKSEKLESISTALVEKAAEM
                     NSLANEVSRLI"
     gene            complement(20533..21000)
                     /locus_tag="J8S10_001589"
     CDS             complement(20533..21000)
                     /locus_tag="J8S10_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HAZ9630175.1"
                     /translation="MVLFDVKKYETPEAKDVDMDRTKHNVGVFLSAYLSARCRIGQPR
                     EPKVTASYSLVPPSTANNTFEAERMMIEREEAQEEFEYLHKLFVRGYSAIQHPHKPDV
                     TERRKKIFYDRYINGLPIYVTAQRNNTSEESVKVESNRIIIQFASSLELVAFK"
     gene            complement(21592..21879)
                     /locus_tag="J8S10_001590"
     CDS             complement(21592..21879)
                     /locus_tag="J8S10_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012197617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630176.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKKRKKPKFKVGDMVRCEA
                     EGFIYPFRGYVEHVYNHSAIIRIENTMECDKWLAKSKENLAVARLVDMKAI"
     gene            complement(21876..22085)
                     /locus_tag="J8S10_001591"
     CDS             complement(21876..22085)
                     /locus_tag="J8S10_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630177.1"
                     /translation="MKIYVVKFGNKFYRSDERSIGANTLFIVDILQSARWFDSLEEAN
                     QVSRRLGGLTQVYELVTVDHEEVER"
     gene            complement(22082..22279)
                     /locus_tag="J8S10_001592"
     CDS             complement(22082..22279)
                     /locus_tag="J8S10_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630178.1"
                     /translation="MKAYTIKFYGNKTYVYILSGLRLDFRGYSKEDLLESLYGYGYLN
                     EDELISLEKFTNAWTIEEEAE"
     gene            complement(22276..22602)
                     /locus_tag="J8S10_001593"
     CDS             complement(22276..22602)
                     /locus_tag="J8S10_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630179.1"
                     /translation="MNYTQQELTDLCPKHVAEFINNEVLPKYADGLNTAENVTDFMIN
                     DAIDRLIFLEIDCIAYYRLHAEVALIDPYIALSQNRKILVAYIDTKQILEGRDVEIEI
                     DEEEVG"
     gene            complement(22599..22880)
                     /locus_tag="J8S10_001594"
     CDS             complement(22599..22880)
                     /locus_tag="J8S10_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630180.1"
                     /translation="MGDMGEYWKDIKPHLKERRKQHVRKMGNSATKNIETLGFEFTHY
                     PNNHQFAINTHNGIIDYWGTTGTWIERKTKKRGKGIRSLRKYINQEDSK"
     gene            complement(22893..23111)
                     /locus_tag="J8S10_001595"
     CDS             complement(22893..23111)
                     /locus_tag="J8S10_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr domain protein"
                     /protein_id="HAZ9630181.1"
                     /translation="MISLTIFWCVIGGLLAMLGAYLIYESAKGKKYTAVGIILFVVGI
                     LVAIGAEINLYLNGTTEELMWFLLWTRR"
     gene            complement(23108..23419)
                     /locus_tag="J8S10_001596"
     CDS             complement(23108..23419)
                     /locus_tag="J8S10_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630182.1"
                     /translation="MDELITKVEQWAKDKGLDQADSSKQMLKTIEEIGEVAASLARKD
                     EHGLRDGIGDVVVTLIILAMQNDMDLYECLNQAYNEIKGRTGKMVDGVFVKSSDLEDS
                     K"
     gene            complement(23596..23910)
                     /locus_tag="J8S10_001597"
     CDS             complement(23596..23910)
                     /locus_tag="J8S10_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HAZ9630183.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKAKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYREILNEYFE
                     ED"
     gene            complement(23910..24215)
                     /locus_tag="J8S10_001598"
     CDS             complement(23910..24215)
                     /locus_tag="J8S10_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630184.1"
                     /translation="MSVGKKAAMKRIIELTHSENWQEDKEIVAEVQKLGKSMWTEKPK
                     RKTPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
     gene            complement(24212..24373)
                     /locus_tag="J8S10_001599"
     CDS             complement(24212..24373)
                     /locus_tag="J8S10_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HAZ9630185.1"
                     /translation="MTTEEVIQMRIRSLQREIDDLERIKAVMVNETARKAINLHIVNL
                     RREIRRLEE"
     gene            complement(24388..24747)
                     /locus_tag="J8S10_001600"
     CDS             complement(24388..24747)
                     /locus_tag="J8S10_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HAZ9630186.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAEANGWKVKLQER
                     FELMPKFELDGKKYRKIEYIPDFTFYKNGKLVKVVDVKGMQTKDFKIKAKLFCHQYQV
                     PLILAKKYRNTFKEERF"
     gene            complement(24744..25595)
                     /locus_tag="J8S10_001601"
     CDS             complement(24744..25595)
                     /locus_tag="J8S10_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAZ9630187.1"
                     /translation="MESLANAMEKLIRRVLVQSGKCPECSEPLYSWRAKNKDGSERCK
                     PTCMSCGYKALRVKEDIQTERIYNDSLKARALSFFQNGSVLTDKTLFKCKMENYHVVD
                     QETKIALERAKSFVNDVLLNHPAHFILSGKSGSGKSHLSMATAWEILERSNYDKKILF
                     ISYQELLEQIKFSYNNAELRKEIEGSLIADIKTTDLVVFDDIGAELGSGVSNSRQFTN
                     NTLNTLLEARQNKATIITTNLSGPELREAYGERIVSRIFKNSEGYALKFQQTADKRIK
                     PVKGSIA"
     gene            complement(25612..26445)
                     /locus_tag="J8S10_001602"
     CDS             complement(25612..26445)
                     /locus_tag="J8S10_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer"
                     /protein_id="HAZ9630188.1"
                     /translation="MSDNKRYYYLKLKENFFDSDEMVLLESMPDGYIYSNILLKLYLR
                     SLKHEGKLMFNDRIPFNSTMLATITRHSVGVVEKAVQIFRDLQLIDVLDNGAIYMSDI
                     QSFIGKSSTEADRKREYRKKIEEAKRNLITGGQVSDKCPDKTTPELEIEIEKDIDIDK
                     EEKKGKYSDEHLRLAKKLQSNLTEDFPKEMNKVDIEKWADTIRLMEERDKASIEAIEY
                     VINWLPTNEFWFGNIRSAKKLREKFEKLKFEIKADKNNHKKQSQKLQYSNPSEYDDLP
                     I"
     gene            complement(26452..27138)
                     /locus_tag="J8S10_001603"
     CDS             complement(26452..27138)
                     /locus_tag="J8S10_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630189.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDIGATINEEVNIDRLKTMYDGYDGD
                     RIIEVRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHNIGVINFKNKYQIKGIKLNQ
                     ETIKKLRIGG"
BASE COUNT         7305 a         5894 c         4311 g         9675 t
ORIGIN      
        1 ctataatcat aattcccgaa gtcgatgctg ttactgtaca tctttttcag cttgccgagg
       61 tcgccgattt gctgattggt ttgattcatc ttgtcttcaa ctgctttaag attgttttgt
      121 gccgatgtaa cgttttgaga aacggtatca atcttagttt gagtagcttg tagttgctct
      181 gttacctcgt caacagtttg atcaattgct tgtgtggctc cctctacaaa ttcatttatt
      241 tgttggtttg ccttttcaat cgtagaatcc acatttgtta atgctgcgtt aacagcatct
      301 gttgcttctt gtttgactcc atcaagtaat tgttgaaagt ctgcaataaa gtagtctgct
      361 ttatcttgcg ctagtccgtc gattgctgaa cgcttcatac ggaaggtgaa gcctaagtta
      421 tcacttgttg atccgtctgg atactcgatg taaacataag cttccaccat accgttataa
      481 gctttcatcg cttctggcaa gatatatacg acctgtccat tcaagaagct ttcagtgatg
      541 aggtttttcg tgataaaagg gattggctct ttcgtgatca ttccatctac ttcatcatag
      601 ataaacatca acaagcgcaa gttagctcct agcaagtccg ccggtgtgcc gttctgttgt
      661 tcgacgttga actctaacgc tatttgatta tcgtatgatt taaatacaag ccccgttgct
      721 tgcaaatcgt agtctttcgg ctgtgtaggt actttgatag agcctttttt gatgacatgc
      781 gccattattt cacaccttca atcttagtta ttttcacgtt gttgctcatt gcgggattgg
      841 aaacattgcc ggatgaaata tctaaagctc tgccgtttga catcgttatc tttcgcgctt
      901 cgattgtcag ctcaaattcg atgaacgtca ctcccgcgtc tccattccat aaattcgctt
      961 ttgtaattcg cgcgtatctt tgacgtttca cttcttctac aaagtctccg tcaccgtctg
     1021 tgtagtggat acgaagcgtt tggtaacgga aagtatcatc tggcagattg actgattgtc
     1081 cttttcttaa ttcgccttca aaaagaacag aagtagtgta aacgcgccgc cagcctaacg
     1141 agttataacc ctctaccggt tcgctgttat gtgtcatttt gatgtaaatt tcgccgctat
     1201 aacgagcaaa agcgacgatt aattttctcg aatcgtgatc cgcgaatacc atcatttcaa
     1261 caaaactgtc atcttcaatc ccgtcagggt tgtctgcgcc ccatccggct ttggttgcgt
     1321 atttgccggg cggaatgtct aaaatgttcg gatatttttg tggtagctta taatcgcgta
     1381 accaacgccc acgcgcttgc ataactgttt ccggtgtagc aaagcccgcg ttgctttcag
     1441 tagctaggac gtgcgcgtcg tgatccgagc cgtcgtaatg gatagccgct tgacgcaata
     1501 accatttcac agcctcttca taactcattt cttcaaaaat atttggtttg ctttgaaaat
     1561 ctaacattta attgttcacc gccttaatag ttataagtga agtctctcgc gcgccctacg
     1621 cctttgcttg tcacttttct tgttgctgtg tcaacttcta ttttataaaa cgctaattca
     1681 tccggtgtat caacttggct agctgtatga gagaagccga cgtcgcaaag aatcattttt
     1741 actgttccaa acgccccttc gacttgttcg tgccaatgcc cgcagaaata acctactaca
     1801 acgccggcgc cttttgtatt cattgcgaag gtctttaatc cgccgaacga accgtcattc
     1861 ggttgtccta atttagacca atcgatagtt accggactac cagatttaaa cccttctatc
     1921 aacgtgctaa tcatgttttc attgcgaacg ggaaacttgc tgagacctaa aggcgtatgt
     1981 cctactaacg ccacatgata gtttctcgga acgttcacta accattctcc gaaagcgtta
     2041 atttgtttgg cactgaaagc tcccggcgct gtatcgctgt aaccgtccac gtacttgtcg
     2101 cctgtgccgc cttcataaaa atcacaagta tcgaaacggt aaattgctgc gtttttatct
     2161 gggaacaaca cgccaccgta caaaccgttc caatactctt cgaagtcagc gttgcataac
     2221 attccctttc gcttgcgcca cgcggggtcg aaacaagcgt cgtgattccc tttgcagata
     2281 ataaccggtt tttcttgtcc tgctaccgct gcgttagtga agcgtttgag cgtgcctaac
     2341 atggaatgtc gcgcgctcca ttcatcaata atgcctatat cgctgccgag tgaaccaagt
     2401 ccgccgtcga tattgtctcc gccgtaaatc atcacatctg ttttgttccc taatttttga
     2461 aattgaggga ttgcgcgcca atgtcttaaa taagaagcat ctttgtaacc gacgccatct
     2521 atacgcaagt tgtgattatc tgcgtgaatg tctgtaatga aagaaaagtt aaatttgctg
     2581 ttattaacac tgttgacaac cgtattcaaa ttgcgcggca ctaggtcaac gtatttcatc
     2641 gtgtcgtaat caaaaaagcg tgttgtttct ctaatttgtg agctgccgac tggcacttgg
     2701 tatttttggt ttaaacgatc agctaatgat tcgtagtcgc ctttagcttc attcagaatg
     2761 ttaatgatca taccacctgg atcgatattt tccagtattt cacgattatc ttctaaccac
     2821 tgctcccagt catttttgcc ctgatccatg taatctttga attttcttag caaatcctca
     2881 aatgtccaca catagccaga gtcacgtaac tggcttctag atattccaga aatgactcga
     2941 taggtaaaat cctgtgtgct aaattgttca ctccaagttc catcaccatt aagtgatcgg
     3001 aaactgaaat gtgcggtgtt ttcaccaccc cattgccagt caggctcact taaggtgtaa
     3061 acaagccttg cttgcgctgg actgtattct tgtacttttt gttcaacagg ttggttttcg
     3121 ccaaattttg ttgtattaat aaaaaacggc actaggccct cgaatgtttt tagtttgcca
     3181 tgttccacca cttcaacaac gaacttttgc gttaaaacat ccccttgccg aattcgaacc
     3241 aaatttattc cgttgtttgg ttcggtggtg gataggacca ttttatgctg cgtttctgcc
     3301 atgactatcc ctcctttaga aatcgatgta gtctcttgca ttgtggaaat gacctgaaga
     3361 agatggataa aactcatcca taaattgaaa atgaagatgt tctccagtgg atggtcctgt
     3421 tgtccccatc agtccaattt gctgaccagc agttaccttc tgaccttttg agacgtctac
     3481 tcggctttga tgcgcgtatc ctgtatacat tccatcagcg tgtttaatca ctgtccaatt
     3541 tccataccag tcaaagtaat ttgcatcacc tgcaacaatc acttcgccat ccgctgaagc
     3601 aaaaataggt gtattaggat ttccatttac aaggtcaata ccgttatgaa attcttgtgc
     3661 tcctgtgatt ggagaagtgc gccagccaaa ttcgctcgtc actgtgattg gatccgcaat
     3721 cggcttcata tatccttttg atacaggaat ttccaaatct ttgaacttgt cataccattc
     3781 ttgtgaccat gccgtccgtt ctggatgtgg atcacgtgga cgttcaaagt tagccacgaa
     3841 tgcttgtgct gctgtgttga tatcggtcag attcatgaat tgtgtccatg tgtaaggata
     3901 agcgctagtt gcgatccatt gaccatttgg tgcatgccac atcaacaatt taaactgtgc
     3961 cgtgattgtg tctggatcat cactgatgcc agcctttgtc attaaattga tcatgtagac
     4021 acgtccgcta gttgcgccag aagaatcggt ccattgccat acaccataac cgaaccctgg
     4081 tgcgccattg ccctcatcag cggttggatt agcatctgat tctccttgtg catttccaag
     4141 taaggctgca gcagcttgtt gtgtaaaacc ggcacctatt gccgttgccc aaatttgcca
     4201 atatcgttta tcccgatcag tagttacttc tggtgggtat tgtccgttcc aaccgttatc
     4261 gttccctccg gaattgcctc ctccattagt gtcaattttt gtaccgttaa catagagttc
     4321 ttttacatct agccgtccat ctatggttat atttccttct gaaaaattgc cgtcaccata
     4381 aagattatat ttgcgcttat cagcagtaac atctgctgga atttgaaaaa taggattccc
     4441 tcgatcgcca ccgtccccag cattaatgga aaaaatatag tttggctctt tccagacagc
     4501 aaagccgtta atccctttag aaccataagt agatacaatt gagcccaagc gttctccatg
     4561 tacatcatct agtccagtag acttgacttg tttttcaaaa gaaagttctc ccccctctgc
     4621 cactaattgg aaatctttat cgtcaaatgt ttttaaagct accccttgca cgaggatacc
     4681 agacagaatg cctgcgcgaa taaaattagc attgaaagtt ccatccaacg tccaagcggt
     4741 cgtgctatca ccattgtgta catcttgaat tgtttgccac tcaccttttt tacattgttt
     4801 gaaagatatc cctgagttat tttggaccat aaaaaagcgt gatctaggaa tgttaggtcc
     4861 atccatataa acagtttcat agatttctct actatcacta acaccagctt caattccatt
     4921 tacccaataa atagaaccgc cattatctcc tgcacctcgc ataatgtcat cttgatattt
     4981 tccaatctct gtcgattcgt aaaatgtcat tttgctagat tctaaactat taatattatt
     5041 gacaatagaa gccgtttgtt ttctaacatc ttgtgttaaa ttatccccta gttcgatatt
     5101 cgtttgaccg gtaagccgat tgaatgtagt tttataaata cgagttttat agtgataacc
     5161 tttatcgtat ctgtgaatag tcactgtatt tcctatcaca tctcctccag tgacttcagc
     5221 tttgaattgt actaacggtc tagcagaatc gattaaggtt gaataagtat ttttaagtaa
     5281 atctgttgga tcatctatat catcaaacac tactacggtt tctcgttttc tcattgatcc
     5341 atctttttgt ggtatcccat acttttgagt tgattccgga tcttcaagcc aattttggcc
     5401 tttaggctta tctaaaggat caccattcga ctttttccat tcaacatcag tgaattcaat
     5461 tcttctaccg taaccgtcac caacctcttc gcctcgccca cgacctatca ttgaagttga
     5521 gattgagctt ctatctatct ctcttacaac tgttaatgct ttactaccat atacgaaacg
     5581 tgtattcgat tcttcgccaa tttgttcata tacttcgatc catttatcct ttattccatc
     5641 agaattcaaa gaacacctaa agacaaattc catacctaag gtttgcaatt ctttcaacgc
     5701 ttcttttaca gagacatagt aaaaagttgc agttactgtt ggtaacattg cttctacgtg
     5761 accaacgcgc caatttcctt cagtaaattc aatcaatcga tcaagaacat tttttaaggg
     5821 ctgcccactc ggcctaatat ctttgatgat gtaagcatct aattcatttg tcgcaaatcc
     5881 taaccctgta aactctaatg tttcaaatgg gtcgctaact ttagtaattc gatacaacga
     5941 aaaagacgac tcgttttcac gaatcgccat atatcttgca tcctctattt ctttatcata
     6001 ttttgtcgta acgtaaagag tatctttcat tagatcactc ttatcagaac taatttcttt
     6061 ttcttgggag acttcaatca aacttcttgt attttttctt ttaataagtt tttgcaagtg
     6121 atcaaagaaa taaactgtct cactcaaatt gtcgcccccc tatagaatat tttaagcttc
     6181 ccattattgc tagttatctt ctgaccttgc ttaagataaa agttctcaaa atcactttct
     6241 aaatcaatca tagaagtaca atcttctccg tttacagtta cctgctcatc ggaaaaatca
     6301 aaaaccaaca cgtctcctgt ttttattgcc gcgtcagtta tcgtgatatt ttgttctccg
     6361 tttgtaattt tgattgaatt attcatggat aaagtaactt caatttttct tggtgttata
     6421 ggaaactgta tcggatttcc aatatagcca tcactaacac actctttcgt atactttagt
     6481 ggatccgcac agaatacatt aaaactcgaa ataatcgagt tggagtctcc tggaacagta
     6541 tcagttgatg tatagcgacc gtagtaataa taatctaatt catcatgaaa cctaatttcc
     6601 acgtcttcat tccggtataa ataattcaac agttctttga atttaaactg tagtttttct
     6661 ggatctctat cttccagctt atatgttatt tttagtgttc ttgaaggtat tttctgattt
     6721 gtaatgattg aaccaatttg tatctcttgc tgttcaactt ctacagaaag catttctcta
     6781 ccttccaccg taagtgtttg ataaccatca atcaaatctt ctaaatacat tccatcgtac
     6841 atcatggcag acgtcggaag gaatcgttta gaactagtga gattaatggt tgtatctttg
     6901 aatgagtaca ttttattttc tcgttgatcc aaaatattcc ctcctaaaat tccagattaa
     6961 tatctgcacc ttcgcccata gcttgtgaaa tatcgtccat aaacaatcta aacgattgtc
     7021 ttccaagatt gattttaaat acagctggtt tagtagagcc acccatattt attttatgtt
     7081 caacttgtgc accaatgttt ttatttgcat ttttcaaatt tgcagctata tctacatcag
     7141 aatttgcatt gaaaagttcc gcgataaagt ctgccatact tccaacagta ttctgtacgt
     7201 cattgaatcc tcctgtcaga cctttattca gaccgttcat aatagcctga ccagctggaa
     7261 tcaatagctt tctatcgtat tggataggtc ctttgtgttc acgaatccaa tcaccaatac
     7321 ctccaacaaa atcttgcaca gatttccatg cattttgtaa cccttctaga aaactatcca
     7381 tgatagcttt tccggctgct agtaaatcga tatttttcaa gttatcaaac cagccagtta
     7441 ctctatcaac cgtgtcacta acagcattta ctaaattatc ccatgcctct tgagcaccat
     7501 ttactaaatt gttgaaagta tctatagtac cttgttttag gttttcccat ccctgaatga
     7561 tgttatcttt ggttccagta attaaatcac caatccaaga tttgaatgaa gtccaaatgt
     7621 ctttagcacc ttgaactgta ttgttgaata aatctatcgt tccttgcttt aagctgttcc
     7681 aactttttat aagagtttgc acgatattat taaccgtttg gaaaaaccat tgttttagat
     7741 tattccaaag ttcaattgca ccatattttg tatcaatcca agtttgaatt atggagaatt
     7801 ttagatttat ccacatttga attgcactgt atttaatatc aatccataaa ttagtaaaaa
     7861 atagtttcaa atcaatccaa atcatagtcg cttgataaac tacttcattc caaatattag
     7921 aaatactttg tatgaatcca gtccataaac taacggcact atttactatt gcaccgatat
     7981 attccgtaaa tatatttttt acagatgtcc aaatatttac cactgattgg acaagtgtgt
     8041 tccagattag atctaaatcc tctttcattt gttcgaagtc accagtaatt aaatctataa
     8101 taaacagtag tggcgcagct attaaagact taatgatttc ccaagcattt actattatgt
     8161 ttttaacctc agcaaatata cttgttattg ctttcactat attagagaac acatctgaaa
     8221 agctacttac aaatggacca atatatttta gtataaaatc aaaaccagat ttgattttac
     8281 ttgtaattgt tttccatgca gtagatatag tatttttaaa cccttcccat ttttcaccag
     8341 cacttgaaac taaatcatca ataactgata tgacaccttc ttttaaacta ttccaaatct
     8401 ctgaagcaga gtttgcaata cttgaccata aatttgaaaa gaactctttt gttccagtcc
     8461 atttgttttt aatccaatct gccgctttcc caggggcttc ttgaactgta gtccaaacat
     8521 tgtctgcgcc ttctttaatg gacttccata aattgttaaa ccattctcct gtagatttcc
     8581 atgcattctg aatccattct actgccgagc ttacagcaga cttgattccc tcccataagc
     8641 caatccaaaa gtttctaaaa tcttcactcg tattccaaag atagatgaaa cctacaacga
     8701 gtagtgctac cgcagctata accagaaaaa ccggatttgt aagaagaccc attgctttac
     8761 ttaatccact aaacaatttt gaactttcac ttaaagcttt aaaagctact ttcaccctat
     8821 tgatccatat aattactgaa ccaatcataa aaattaacgg tcctatagca gcgacaattg
     8881 ctcctatggc cactactaat ttttgagttg attctggagc acttacaaat ttttctacta
     8941 agccggatat ggcatctgct acttttttga tggatggtgc tagaatcttt tgaattacaa
     9001 tagctgctga ctcaaaagct ccaaacattt gctcgatgga agaattcata ttatcttgca
     9061 tggtccgagc catatcgtca gctgcaccat cagaatcttt cagagatttt gttaatttgc
     9121 ccaatgaatc aggtccttta tcaatcaaag ccatcatccc tgataatgat tcttgcccat
     9181 atagtgttac taaagcattt tgttgttgtt caggcgtcag gccttcaaaa gcttttttaa
     9241 gtaattctac ttgagttttt aaaggtttca ttttaccgtc agcatcataa aacgaaacac
     9301 ctaaattatc cattgtatct tgcatagcct ttgttggcct tgctaaccta gacaatgctc
     9361 ctcgcaacgt tgtacctgct tgagaaccct taatgcctgc gtcactcata ataccaatag
     9421 ctgctgcagt ttcttccaaa gaaatcccca ttgaattagc tacaggagca acatacttca
     9481 atgcttctcc catgtctcca acttcagcat tggtatccgc agcagcacga gcaaatacat
     9541 cagcgacatg tcctgcttca cttgcttcta aaccaaatcc tctcaaagca gtagcagtat
     9601 tttcagaagc tagagccaca tcccctccag atacagctgc taagtctaaa agacccggca
     9661 ttgctttcat gatttcttgt gcgctaaatc cagcagaagc taagttttcc attccagcag
     9721 ctgattcttt tgcgctaaaa gcagtttttg ctcctagatc aatcgcttgc tgtttcatct
     9781 gttcgaatgt gtcgccggtt gctcctgata tagcttttac acgactcatt tgtgcttcga
     9841 agtcgccacc aactttagca gctgctacgc ctactcctat aagaggagtg gtaatatact
     9901 ttgtcattgc ggcaccagta ccttgcatca ctttaccaac agcggttgtc atactatttg
     9961 aattcttttc aaaagtttta acagcatctt gtgcatcttt aaaagtcttt acaaatccac
    10021 tatctgtggc ttttaataag gcttcaacag aaaattgttc catgattctc ctcctttcct
    10081 caagagttag ctttagttag taagctttgg aattttttat cttgttttga aagttcggaa
    10141 actcccatga ttgaatcttc gattttttga taattgaaga attcttcaaa ggatcgatat
    10201 acaggaactg tctttttgcc tacttttttc tccgcttgga cttgctgatt tgcccacgct
    10261 aattcgtgaa tcaacttttc tttgtcaagc caagataact gggctgcagt catacgaatg
    10321 ttgtattcat ataacgtcat tctttcgata tctgagatat tggtcattcc caaatatcga
    10381 aaagaattga taagaatttg ttcgtatgcc agtgcagaat ctattccact tgttgttttt
    10441 ccgcttcttt caatttctga ttcaggtttc ggaccgctaa ctttcccgcg ttcgactccg
    10501 ccaattcttt taggacttca tcaaacaatt tttcaatgtc tttaacttca tcgatgtaat
    10561 catccaattc atctaatgta atagattcat cttcagttct atttgctatt tccagaactc
    10621 gtgataacgt gttaacgtta taagaacgta gctctggtaa gacttttgcg gagagtccca
    10681 ttccaaattc catatttcca tcgacgaaag gcatcacttt atctaattca cgtacaaatt
    10741 tagtgccaaa tttaaacgaa tattctttac ctttaatttt taatttcaat gtttttcatc
    10801 ctcctaaaat aaaaaagaga gcatctaagc cctcttatgc tcctgtcgaa gttgctttca
    10861 cggtatcttt gaatgcatat tgaacaacat cggcttgatc ttctgtcaag gttgcataac
    10921 catcttgacc aacaccattt actgcaaatg ataaacttaa ttcaacgtta tcctctgcag
    10981 cagccgatgg agtaaattca gacacatatg cttggtaata agtagctttg tacttatttg
    11041 cattatcatc tgttccctgt tctgctttat taatttccca aatttcaatg atatccccat
    11101 ttaataaagc ttgtttcatt tcatctacat gagaatctcc tttagcaact attgaagtag
    11161 ccgaaaaatc atattcaacc gggcttaaac tttgaacgtt tccatctttt gtcactgtag
    11221 agtctgaatc tcttgataaa ccattttcgt gttctgtttg aaatgccatt ttccaagcgg
    11281 cttcctgagt ttcttttttc aataagcgat aaagcaaaat gacatcaata ccttttaatg
    11341 cttccatgtt cttcctccta tctaattcta aattcaagtg tgacaaccgc ccgttttagc
    11401 ggtgtattcg ttgttgtgtc gtccatcact tgaattccac ttgcttgata atttaaagcc
    11461 caataatagc cttctgtggc ttctatcaat ctagcttcat taaaaagagc agatgccata
    11521 tctgacaact gctttcgttt cttctgtaat ccccaaacgg ataaaaccac aatcacagac
    11581 cctttaatgt cagttttatt tacttcatgg attgtctgag tgttctcaaa ttccacaaaa
    11641 ggataaccaa catcctctaa agttttgtaa tcgtatgttt tatatccaag tttgttttgg
    11701 gatattttaa aaagttcatc aaaaattgat tgatctcttg tcttaatcat catttcacca
    11761 aggctttcat ttcagccata aatttgactt tttggtaatt aaacgctggt ctaacataag
    11821 gctgtgccga cataaatcga gtgccatatt ctacataagg tgcataatct gctgtcggtc
    11881 ctacaatacc agttaaacca gcttctaaaa gattcatgtt tattgatctt cgtaagtaac
    11941 ctgtatccac tggcgcacct ttttgcattc gttcagtcat ttcagcagta ttacttttca
    12001 cgactttttg aacgtcatta agcgttgctg cttttttcag atgtcgcatc agctgatcga
    12061 ttcctttata ttcaagttgt gccttcatca agaaccacct cttgcacaat taaactattt
    12121 ctatatgctg gatttctagc tgttttttgt tgccaagtct ttccttcaat ctcgatatag
    12181 tcaaatgtag ggatagaaaa aagaggctgc gtcctaatga ccttcgcccc ttcttccaca
    12241 ctaccaaaaa tagtcacact tctatcagtg ccaatatctg tcacgtttgc ctctgttctt
    12301 gttctttctg gtttgccttc aacccactca ccgagatctg gatcatattt agagtcagat
    12361 gaacgtttaa caaatataat ttcatctgta aatctcatac aaatttaaac ctccctcgct
    12421 ttggcttgta caactcttcc tgatctttac gcttaaattc atcaatctca ttttgatact
    12481 ctgaaaaatc cgagtcagga aaagccatag ataaaccttc ttgagaatat gactgcatac
    12541 cttcttgacc aattctattg aatcttttca acgatacttc atatacaact gtttcaaatt
    12601 ctttaggaac ttcttgcgta tttaacaagg ttttcatacg ctcattcgtt cttcgctcaa
    12661 taacttcaag cttttcatct attgttcctt taagaagttt tttaatatca tctgcaatca
    12721 tcatattttt acttcctaac tagcaggttg acctgtcaca ttgattgaag tagtgaattc
    12781 tccagaagta aatgtgaatg ttgctgaccc ttctgctgca atcgttccat caaaaccacc
    12841 attttcattt ttggtcactg ttgcgatagc tccatcactt gaagttgctg tagtagctgc
    12901 aacaacagca gctgcatcgc tagcatctgc aggcacagct gaaatagtaa atgttttagt
    12961 atcgcctact ttaccggtcc atgtcttttg atttggcaca ataccggtag caggcgttac
    13021 gcttttgggg aaatcttccc aaatgcttca tcttttacaa tcataaatcc aacatccatt
    13081 gttgcacgca aagcaatcag ttcttgctca aacaagttaa ctggggttcc atcttcatta
    13141 gttaaagtag acaattgggc ttcttcagaa atcttaaatg aaatattata tgggatccca
    13201 taaaacatgt aattaaagtc tccagcgtaa agtgttcctt tatctaaaga cttaaggtct
    13261 actactggta atccgtcaat tgtattagta gagcgatcat aaataaactc aacatttgac
    13321 ccgactgttt gagctgcaga acgtaattct gtacgatttt ttcggtttga aataaacgca
    13381 ttaggttcga attcattttc tgctaacttg tcttctaagg ctaggatatt atcataagtc
    13441 aatccgcctt caaccacatt ccccgcacta ataactgatc cgtctagtga ctgaggaaat
    13501 gggttttctt tatttaataa ggcagctgca tcaaattttt tatagaaagc ttcagcaatt
    13561 tttggctgca tctcctcaaa gaaatctgat aatttataat ttaaatattc acgagaaacc
    13621 ggaagaatga caccgagttt ttttgcagtc atcgtagctt gcatccattt aggtttagac
    13681 gttttaattt tttcaccttc acccacccag tatgcgcctg gtccttctgc aaagtattca
    13741 aatttctttt ctttgtcagt catttcttcg tattttgcta actgcatgat cttagaattt
    13801 tccataactt cactcaaaat gagcgtatta tatttatcag gaatttttcc ctctttcgtt
    13861 tcatatacca agacattatc tggatcccat gtttgagcaa acatttgcaa gttcattggt
    13921 aaaagttgtt tctttttcat taagttttcc tcctatttga taattcgatt tttagcagct
    13981 agtttagcca ctgtttcttt agtatttttc gatgctgtaa attgtccacc ttcatttggt
    14041 ggtgtttgtc ttgcgttttc tctcttaatc aaagaagcaa agttagtgat gactgctaca
    14101 gcttgttttg tggcatctgc atcatcagaa acaatcagac caagtaaatc atcatcgtgt
    14161 ggtaaatttg catctgtcag cattttagaa gcttctttcg tcatttcaga tagtgcctgt
    14221 ccacgcttta attcagcgat ttcagcttct ttttgctcca actcatgctg tagtttttct
    14281 tccgcattca tttttgccag ctttttagct tcttcttttt ttgctgctag ttctttttcc
    14341 cacgctgctt ttgctttatt cgtctcagca gcgatcattt tcgctacttc atcacgagaa
    14401 aatgttttgc cagtattgtt ttcttctttt gcttcgggcg gtgtctcttg tgagccagct
    14461 ggtaggtttc cttgttgtcc ctcatcacca gatccaccat ctcctggttc agaaaaaaat
    14521 tgtaagttca ttggcataaa taaacgtttt ttcatgatta atcctccacg gttacgccgc
    14581 tacccgataa atttgaccag ttacgccggt cagccgaaaa tagctttctc tttaacgcct
    14641 gtaagctgta agaaggcaca ataaaaagcc gttaatttgt gttaacggct tgatattcgt
    14701 tctatataag gtgctgtact gcatcgacaa aatggatgca tattaggagc gttacttcct
    14761 ggctgcatat cggcaacatc aaaaacttga ttatttaacg gtatacatag tttgcacgcc
    14821 gttggttctg ctatatagat gtactgggta atgcctgcat ctctataact tcgttcttga
    14881 atccctacct gaactctagt cgtttcagtc accatcaaac gttgagtgtt gaacttagtg
    14941 ttttctcgtc cttcagctgt taaatattct gccaatttag atgcaagttg cttgggattt
    15001 ttccccatcg ttatacttct gactaacaac ctatctaatt ctgatttcaa ttcagattga
    15061 tacatccata agcgatcact aaaagacacg tcatcactca aaaaggagct gtttattact
    15121 agttctatca gctttgcata tccacttgaa gcaatagtca tttctaaaat accggcttgt
    15181 ctcttcaatt cagctaaacc agcttttgtt aattcattcg aaaagtactt atccaattca
    15241 ttaaacagtg aaatcaattc aagcccgata ttagctttta agagctctaa tctatttaca
    15301 cgcatcgtaa gattgtatag ctttaattct tggtttgctg taggagaaaa atctttctct
    15361 ttgacatact tctttgcttt gcgagcgaat gctttgacat ccatttcact agcacgcttc
    15421 atcgcttcgc tacgagtgat tttctggcca ttggagaaac tgtcccactg cgcgtctatt
    15481 tctttttgta tcgcatcttg tgcgtattgc atgcgacttt taatttctgc catgcgcttt
    15541 ttatcatctt taatttgttg cttttgccat tccttttccc gtttgatcca atattcttgg
    15601 gagttcattt aatcaccccc ctgtttcatc ttttttgttg ttaattactt cttcaccatc
    15661 tgaatcaaaa atgccaatct gcttttgcgt ttctttattt actcgtttca actctgcctg
    15721 tacatctgga acaaaagaag cgagtcctaa gatcgtctct tgactgagtt cagctccagc
    15781 atcaaccaaa gatttcaact cttccagaat ggctttaggt agattaggcg taaatattac
    15841 acgtaagcct ttcaaatcgg agttatccat ttcagaaata cttgatttta ggctaaataa
    15901 aagacgataa cgccgcataa ggcctttttt gaatagcctt tgctttgttg ccgtcatttg
    15961 ttcaaatcca aataatttat atttcattgc ttctcccgat tgcactccgg aaaaattgtc
    16021 atcagtaaga tcaggaacca tggatatttc gtgaatatcc ttgcgtactc tgtatttgta
    16081 tgcttctaca ccgttcacat catattgttt gtaaatatat cctgcagtca cacttgtttt
    16141 attaccgttc acatcagttc cagactcaag caaaagcata ttcgcttctt tctgcttgat
    16201 ggcgtcctct gtggatagtc ctgctgcttc aatatcacca ctaataacta gaagagcatc
    16261 gtttagatca gtcatataat tggcggtatc agactgccct gcatcgtata gatcaatcaa
    16321 agatagtaca tcttcataca agcccatccg aaaacgatta ggagaatact ctgtaatagg
    16381 tacctcttta tattcatgcg gttcatcctg gggattcttt aactcaattg ctgttagtgt
    16441 cgtctcatca taagtgatac ttttttcttt tgtgtatacg attggttgaa tgtactgttt
    16501 atcagcatcc ttgttgaatc ttgtcttagg ataccgtaca gccaaaatag gctctcgttt
    16561 tactgtagta tcatatacaa caaacgtttc aaatacatta gccaaatcaa cataatctgt
    16621 atcatctgaa tctcgataga taatctcata ggctctccca tacttatcca tatcaagcca
    16681 gagttcagca tttaacccat ctatgtcatt attagtatta aactcttcga tttctttttg
    16741 ttgatttgtg tcctcgattt gcacttttat aggattgcct gtgttgtacc caacatcaaa
    16801 cgtacaaaga acttttccaa agttatgtgc tgatcggtga tccgcttttt ctttttctct
    16861 gcgcctacgg ttatccatga tatttgtatt tctagcttta taataatcat ctaatacact
    16921 tagccttttt acctgatatt catgatgatg ttttatcatt gctgctaaag tatctaaatc
    16981 gttaagtaaa tcttctgctg agctaaatct atagtgaaga tttgagtcta cgctaaactt
    17041 tacataattt gtgttcacgt cattagaata atgtatatca gctccgtatt caaactcgtt
    17101 taccttatcc atttttcaca ctccttaaaa catgcgttta atacgtttaa tcttttcgtt
    17161 gacattaact tttggtttct taagaagctc atgagtatat atcgcatatc gaacggagtc
    17221 tagcacatca tcatattctt ttattggctc gccttttttc ttgtcccaaa tgtattgata
    17281 aatttcatcc cgaaatttca tcactctatc ttgacagata aacaatttat cttgtttaaa
    17341 tctcttggcg acttcctcaa ctccagataa ccgtgcttta tgagcatttt tagcattaat
    17401 cttttctctt acaaacctag ccacatgctc cggtctcgca gagtcacaat aaaaaggtac
    17461 tcgtaagccg taacgctctt gaatgccttt tgccacatct acccaataat caatctcttc
    17521 aaattgagta gcatgttctt cgattaaata agctgttccg tcatccgttt cacctataac
    17581 tacgattgaa ccccagtgtt catatcccca gtcaacacca caataaaagt tgctcaaagg
    17641 tggtaagtct tttgactgga tgtagtgctt gctagcatca aaatcacgat aaacgacacc
    17701 ttctgcagaa acccataaac ctttgatatc acgatcataa aacatgccgc ttggtgttga
    17761 ttctttaata ttgttacgat atcgttcaga taaaaatgta ttatcatcta attcaaagtg
    17821 gaacgattga atatttttgc ttgaattgtc gatatactct ttctttagcc agtgttccgg
    17881 gttgtcaggg tttgtatcag ctagtattct cgctcctgtt cctgaacaac gtgaaacgat
    17941 ttcagcaaat acttcttgtc tagctagcga tgcctcattg atataagcgc catatgctgt
    18001 cataccacga attgcgccaa caccgccaat gtttcctgta taagcttgta cgaccttaac
    18061 gccaaatagc ttaaagtttc catgtttatc gaatttaggt tctatgctgt acatgttgta
    18121 tagttcctgt aagatgttct tttggattgt tgcacttgaa actcctgcta ggatatacat
    18181 tggttcctta atgtcttctt catcggcaat ctttcgcaca cgtcgcaatt caaacaagaa
    18241 caaatcattg tttatttttg tttttccaga acgttttgct ccatgtaata aagtaataaa
    18301 ccaatcattc ttaatggttt tatttaacac gtcgatttgc tttgggttat aaatatcaac
    18361 tagtgccatc taattcacca ctaatctttt ctaacaactc atcaagtttt tcttcggtag
    18421 aacgctctga gtttatctgt aattgttcta attttgcttg cattaatttt atttctgttt
    18481 gagctttttc taattgcgtt tgtgataaca gcgatttata cttcaaatac aaatccaagg
    18541 ctttcaattt gctttctaaa tctggtgtat attcatattg catatgttta ataaccttgt
    18601 ttttctccaa gcggtctatt tgcttgctca cgcttatttg tacttctcct tgccaaatat
    18661 ctatcaattc atttaaagcg tcctcggcac ttaatttgcg cttcttttcg ataggattta
    18721 gccgttcatt aatatactgt attatgttag gtttagttag gttttcctta cctattactc
    18781 ttgctgatcg tttgctataa cctgctttaa tggcggcttg agtagcatta ccaccatttt
    18841 ttatatattc atccgcaaaa gctttttgtt ttggtgtcaa atttaccaca ttcaagccac
    18901 cacctttcaa ttttattaac aatatctctc aatatttgtc tgtatgttct gctcactaaa
    18961 atatccatgg ccgcagtaac gaagattgta cttatcaatc tcttttggcg tagcttctct
    19021 ggtcatttca atgatggagt acttcttttt aatctggact gactggacaa ctctaattgg
    19081 atcatctgcg tttggttgcg gatatttatt tgataatgat acataccagt agttcctcat
    19141 tacgtatcac tctttctgtt ggttactggc agaaaaggtt cgcatcataa attccatagc
    19201 ctgtgcgtca ttaaatcctt gcagaataag ctgatcgtag aaatacttag cttgttttgc
    19261 gattaacgct aagctttttt gagtttcgta gaatgtcgcc tccattgttt tgtttgcttc
    19321 attcgtttta aacaactctc ttaattggtt ttcgttcatt tttttactcc ccttccaaaa
    19381 taaaaagacc actcgatgag tgatctaata tgtaaaaact acacctcata aacgagatgc
    19441 agttatagtt ctatcaagca acctacaccg attccatcga ttactatcga cctcgccttg
    19501 ctcgtgtact ttgagcgccc atttccaacc ctcagttgcc aaagtcactg gcaaggaatc
    19561 gaaccttgca tggttgccga agcattgacc taacacacat gcttagcgtc taccctttcc
    19621 gccacagtga caaattaata ttgtgaaaat aaatactaag tgtataattt tatttatcag
    19681 cgagtggtcc gctgaaataa attaaaaggt ggtgaaaaat ttgtactttg ttataagaga
    19741 agcaactaat ggccaatatt acttcgttat taagtccgat aacaatgaag tagtagcaac
    19801 tagcgaaaca tacttgacta aatattccgc tgaacaaacc attaattcta taaaaaacgg
    19861 aatcaccaaa gactctcaag ttatcgatgt gactaaataa gacgactaac ttcatttgct
    19921 agggagttca tttcagctgc tttttctacc aaagcagttg agatactttc tagcttttct
    19981 gatttaacag aattaaatac tggcgtcttg atactaatcg atacatcttg acgaggatca
    20041 ggactcgttg ctctattttt ttgcaccact gatctgtact tttctactga atgatactca
    20101 attacttgtt ctaaatgttt tttgtactct ttacatacag cttctttttg gatcaattct
    20161 aaacgttgtt gctcaataat atcaatcaac cgttcccgat ccataccttg atactttatt
    20221 tgctcgactt ccattcgttt tccctccaat acataaatta ataaacagca acggatgata
    20281 gataataaga acaatttaga aggagttgga attcacatcc ttattcttaa tatttccgtt
    20341 gctgtctatc gaagcttaat tgtgaaacaa taataaaacg atgttccttt tattattatt
    20401 ttgtctcaga cctatcacta atctttcgac actatcataa taaatcattt accaggtaag
    20461 tgattggtat aaaaaaggta taaaatggaa accaaatggg taatcaaagg gtataaaaag
    20521 tgtaaaaact ggctacttaa aagcaaccag ttctaacgat gaagcaaatt ggatgataat
    20581 tctgtttgat tctactttaa ccgattcttc gctagtatta ttcctttgag cagttacata
    20641 aatgggcaga ccattgatat aacgatcata gaatatcttc ttgcgccttt ctgttacatc
    20701 aggtttatgc ggatgctgaa ttgctgaata gccacgaaca aataatttgt gcaagtactc
    20761 aaattcttct tgcgcttcct ctctctcaat catcattcgt tctgcttcaa atgtattatt
    20821 tgctgtagaa ggtggaacca aggagtaaga tgccgttact ttaggctccc gaggttgacc
    20881 tatcctacat ctagctgaca gatatgctga aagaaaaaca ccaacattat gttttgtgcg
    20941 atccatatcc acatcttttg cctctggtgt ctcatacttc tttacatcga aaagtaccat
    21001 ccattgattc ctccatttat gatataataa ttgtgtcaga attattaatt aaggtcggag
    21061 gaatccggct ttttttatac ccatgcttat gctaagcttt tcaagtagcg aggttgcact
    21121 cgttacccat atacatgttg agctatctgg cggaaaacag atggctcact atttcaatat
    21181 tctgctaagg acagccagtg gtcggctgtc ttttttatat tttaatgaga agccttactt
    21241 atttttttat ctttattacg aaaaatgata ttatctattg ataataaagc gtataggaga
    21301 tggttgagtg actatgtgga gcatgctgtt attttggatt cccgtttgta ttggtatcgt
    21361 cgcattttgt tactttgtca aacactctag aacaaataag ctcctcatgt tatctttttt
    21421 acctatagta ttttttattg tacaaattgt taaatatacc tatattgaat cgcaagaaat
    21481 attcattttt tatgtggtag gtttatttat ctctgtggtc tttttcataa tgatactttc
    21541 ctatttttat aaaaaataaa tttttctctt agaagtacat tttttcgctg tttatatagc
    21601 cttcatatcc accaatctcg ctacagctaa attctctttg cttttcgcta accacttatc
    21661 acattccatc gtgttttcaa tacgaatgat cgctgagtga ttatagacgt gttctacata
    21721 tccacgaaat ggatagatga acccttctgc ttcgcagcga accatgtcac cgactttgaa
    21781 ttttggtttc ttacgttttt taggattctt tgtcggcata tctagcatta aaccgccgat
    21841 accatgacta ctagcgtaaa atccgtcttt taatttcatc tttctacctc ctcatgatcg
    21901 acagtgacca gttcatatac ttgtgttaat ccaccaagtc gtcgtgaaac ttggttagct
    21961 tcttcgaggc tatcaaacca tctcgcactt tggagtatgt ctacaatgaa taatgtgtta
    22021 gcccctatag agcgttcatc acttctataa aatttattcc cgaactttac tacataaatc
    22081 ttcattctgc ttcctcctca atcgtccaag catttgtaaa tttctctaag cttattagtt
    22141 catcttcatt taaatatccg taaccatata aggattctaa aaggtcttct tttgaatagc
    22201 ctctaaaatc aagtctgaga ccgcttagga tgtatacata ggttttattt ccataaaact
    22261 tgattgtgta tgctttcatc ccacttcctc ctcatcgatc tctatctcga catctctgcc
    22321 ttctaaaatc tgtttggtat caatataggc tacgagtatt tttcgatttt ggcttaaagc
    22381 aatatacgga tcaatcaaag caacttctgc gtgtagacga taataagcaa tacaatctat
    22441 ttctaaaaat atcaaacgat caatagcatc attaatcata aaatctgtaa cgttttctgc
    22501 tgtatttaaa ccatctgcat atttaggcag gacttcatta ttgatgaact cagctacatg
    22561 ttttggacat aaatcagtca gttcttgttg tgtatagttc atttgctgtc ctcctgatta
    22621 atatatttcc tcaaactacg tatcccttta ccacgttttt ttgttttgcg ctcaatccac
    22681 gttcctgtag ttccccagta gtcaataatt ccattatggg tattaattgc aaattgatga
    22741 ttgtttggat aatgagtaaa ttcaaatccc aaggtttcaa tatttttagt tgctgaattg
    22801 cccatctttc tgacatgttg ttttctacgt tcttttagat gcggtttaat atctttccag
    22861 tattcgccca tatcgcccat ttcgctgtcc tcctatctcc ttgtccacaa taaaaaccac
    22921 atcaactctt ctgtcgtacc gtttaaataa agatttattt ctgcaccaat cgcaactaaa
    22981 attccgacaa caaacaaaat aatccctact gctgtatatt ttttgccttt tgcactctcg
    23041 taaatgaggt atgctcctaa catcgctagt aagccgccaa ttacacacca aaatattgtt
    23101 aggctgatca tttgctgtcc tccaaatcac tcgacttcac gaatacacca tctaccattt
    23161 ttcctgtgcg tcctttgatt tcgttgtatg cttggttcag acactcgtac aaatccatat
    23221 cattttgcat agctaaaata atcaaggtta ctactacatc tccaattccg tctcttaaac
    23281 catgttcatc ttttctagct agagaagcgg caacttcccc gatctcttcg atcgttttta
    23341 acatttgctt gctggaatca gcttgatcca atcccttatc tttagcccac tgctctactt
    23401 ttgtgattag ttcgtccatt attcattctc ctttatatat ttaagttgga taatacaact
    23461 tgtaacaaat gaagctaatg ttaaaattgt gccgattggt gttaaaaaac cgctttttat
    23521 cgcattaatt aatatagcta caaatatcgt tatatagaat aaaaagtgaa ttgacgctaa
    23581 cgttgaatta aacatctagt cctcctcgaa atactcattc agtatctctc tatacttttc
    23641 tacaaatttg aaacgatcct gatgaagttt cttgctccaa tttgtttgcc gatccagctc
    23701 acgcatctga tcgaaccctt tttgaatttc gttgtaataa aattcaatgt ttgctgctgc
    23761 tttccaatgc ctgctacttc gcactcctgc tcctgtttca gccatttcca acttaactaa
    23821 ttccgctcgt tcttttgctt ttttatcttt ctgaatcttc atcatgattt tcttgaggat
    23881 gatatcactg tattgtgtaa tgagatccat tatttctcct ccacatacct aaactgtcgc
    23941 ccctttgaat caatccataa gctcctagct ctatcccaga tgatgttttt gctcagtcca
    24001 gtaatttcag ataactgttc agctgtaccc gttactagaa ttcgatcacc atgccagatt
    24061 gcaatttttc tcggcgtttt ccgtttaggc ttttcagtcc acattgattt accgagcttt
    24121 tggacttctg caactatttc tttgtcttct tgccaattct cagaatgtgt cagttcaatg
    24181 attcgtttca ttgctgcttt cttacccacg ctcattcctc caatctacga atttcccttc
    24241 ttaaattcac tatgtgcaaa ttgattgcct ttctcgccgt ttcattgacc atcactgcct
    24301 ttatccgttc cagatcgtca atctcacgtt gaaggcttcg aatacgcatt tgaatcactt
    24361 cttctgttgt catgatggac cacctcgtta aaaacgctct tccttgaacg tattccgata
    24421 ttttttagct aatatcaacg gcacttgata ttgatgacag aacaactttg ccttgatctt
    24481 aaagtctttt gtctgcattc ctttgacatc tacgactttg acaagtttgc cgtttttata
    24541 aaatgtgaag tcgggaatat actcgatctt gcgatacttt tttccatcta gttcaaattt
    24601 cggcatcagc tcaaatcttt cctgaagttt tactttccag ccgttcgctt ctgcttgcca
    24661 caaggctaaa tcgtaatact ctgcttccgc gatagaatca aacttgatac ctcgatgaac
    24721 agttttctta ttacggtatt tattcatgcg atactacctt tcactggttt tatgcgcttg
    24781 tctgctgttt gttggaattt cagcgcataa ccttctgaat tcttaaatat tctagaaaca
    24841 attctttcgc cgtaggcttc tcttagttca ggaccggata agtttgttgt gatgatcgtt
    24901 gccttgttct gtctggcttc taagagcgtg tttaacgtgt tgtttgtaaa ctgcctacta
    24961 tttgataccc cgctacctaa ttcagctcca atatcgtcaa aaaccaccaa atcagttgtt
    25021 ttgatatcgg ctataagcga tccttcaatt tcttttctca gttcagcatt gttataagaa
    25081 aactttattt gctctaataa ctcttgatag cttataaaaa gtattttctt gtcataattt
    25141 gagcgctcaa gtatttccca agctgtcgcc attgacaagt ggctttttcc gcttcctgat
    25201 ttccctgata gaatgaaatg tgcaggatgg ttcagtaaga catcatttac aaagctttta
    25261 gctctttcta aagcaatttt cgtttcttgg tccactacgt gataattctc cattttgcat
    25321 ttaaacaaag ttttatctgt taataccgaa ccattttgaa aaaaactcaa cgctcgtgct
    25381 tttaagctgt cgttatatat ccgttcggtc tgtatatcct ctttcacacg taacgcttta
    25441 taaccacaac tcatgcatgt tggtttacaa cgttctgaac catccttatt tttagctcgc
    25501 caactataca aaggttcgct acattctgga catttcccgc tttgcactaa tactcttctt
    25561 attagtttct ccatagcatt tgctaggctt tccatgtgat gcatctcctt tttaaattgg
    25621 caagtcgtca tattcactag gattgctgta ctgtagtttt tgactttgct ttttatgatt
    25681 attcttgtct gctttgattt cgaatttgag cttctcaaat ttttctctca atttcttagc
    25741 acttctaata tttccaaacc aaaattcatt tgtaggtagc caattgatca catactcaat
    25801 cgcttctata gacgctttat ctctttcttc catcaacctg attgtgtctg cccatttttc
    25861 gatatctact ttgttcattt cttttggaaa atcttcagtt aaattacttt gcaatttttt
    25921 agcaaggcgt aagtgttcgt cagaatactt acctttcttt tcttctttat ctatatctat
    25981 atctttctct atctctatct ctaactctgg tgtagttttg tctggacatt tgtccgacac
    26041 ttgtcctcca gttattaaat tccgttttgc ctcttctatt ttctttctgt attctctttt
    26101 tctatctgct tcagttgagg attttccaat gaaactttgt atatcagaca tataaattgc
    26161 tccgttatct aatacgtcaa taagctgcaa atcacggaaa atttgtaccg ctttttctac
    26221 gactcctaca gaatgtcttg taatagttgc gagcattgta gagttaaatg gaatcctgtc
    26281 attaaacatc aacttacctt cgtgttttag acttcttaaa taaagtttga gaagaatatt
    26341 agaataaata tagccatctg gcatactttc taagagaacc atctcgtcac tatcgaaaaa
    26401 attctctttt agttttaaat agtagtagcg tttgttgtca gacaatattt tttaccctcc
    26461 tattctaagt ttcttaattg tttcctggtt taacttgatc cctttgattt gatatttatt
    26521 tttgaaattg atcacaccta tattgtgttt ctccgtgtga tgaatcctgc agagtgctgc
    26581 aaatgtgtac tctgaatgat caacttcttt gcgctttcgt cttcctagcg ctttgtcaaa
    26641 gtgatcgatg tcagctcctg ttttgccaca gatgcagcag actctttttg tgatgcattt
    26701 gtagaagtaa tattcttgat tcgctggtaa aatctcatag ccttctttga aaggaatatg
    26761 atgttcaaag atgaaatcta agatgatatt tgctaagaca ttagcatcac tcacagttgt
    26821 attcgattcg tctttgaggc ttattttgcg ccctgtgacg ccttcaaaac ggaagtaaaa
    26881 gaattccttc cagaagtccg ttggcatgcc tgtatcgatg aaaatatcgc ctatcagcgc
    26941 atagatgaag tttcgttgct gcacagtaaa tcgacgtgga tcaataaatc gaacttcaat
    27001 aatccgatcg ccatcatatc cgtcatacat cgtctttagt cgatcaatgt tcacttcttc
    27061 attgatcgtt gcacctatgt cttttccttt gaactttttc agaaccgctg aatatgaatc
    27121 gatcaatggt ttaaacactc atatcacttc tcttttgttt cttctctgta ctgatcttca
    27181 atcca
//
LOCUS       DADQDV010000036        26627 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.036, whole genome shotgun sequence.
ACCESSION   DADQDV010000036 DADQDV010000000
VERSION     DADQDV010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 26627)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26627)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26627
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.036"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(29..1729)
                     /locus_tag="J8S10_001604"
     CDS             complement(29..1729)
                     /locus_tag="J8S10_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630190.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            2236..3396
                     /locus_tag="J8S10_001605"
     CDS             2236..3396
                     /locus_tag="J8S10_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAZ9630191.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            3412..3855
                     /locus_tag="J8S10_001606"
     CDS             3412..3855
                     /locus_tag="J8S10_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAZ9630192.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(4338..4868)
                     /locus_tag="J8S10_001607"
     CDS             complement(4338..4868)
                     /locus_tag="J8S10_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HAZ9630193.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            4973..5524
                     /locus_tag="J8S10_001608"
     CDS             4973..5524
                     /locus_tag="J8S10_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAZ9630194.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            complement(5677..6150)
                     /locus_tag="J8S10_001609"
     CDS             complement(5677..6150)
                     /locus_tag="J8S10_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAZ9630195.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            6288..7760
                     /locus_tag="J8S10_001610"
     CDS             6288..7760
                     /locus_tag="J8S10_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAZ9630196.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            7757..8467
                     /locus_tag="J8S10_001611"
     CDS             7757..8467
                     /locus_tag="J8S10_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HAZ9630197.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            8819..9103
                     /locus_tag="J8S10_001612"
     CDS             8819..9103
                     /locus_tag="J8S10_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HAZ9630198.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(9420..9803)
                     /locus_tag="J8S10_001613"
     CDS             complement(9420..9803)
                     /locus_tag="J8S10_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HAZ9630199.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIK"
     gene            complement(9805..10389)
                     /locus_tag="J8S10_001614"
     CDS             complement(9805..10389)
                     /locus_tag="J8S10_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HAZ9630200.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            complement(10436..11911)
                     /locus_tag="J8S10_001615"
     CDS             complement(10436..11911)
                     /locus_tag="J8S10_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HAZ9630201.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            12092..12403
                     /locus_tag="J8S10_001616"
     CDS             12092..12403
                     /locus_tag="J8S10_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630202.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            complement(12518..14854)
                     /locus_tag="J8S10_001617"
     CDS             complement(12518..14854)
                     /locus_tag="J8S10_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAZ9630203.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            14996..15664
                     /locus_tag="J8S10_001618"
     CDS             14996..15664
                     /locus_tag="J8S10_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAZ9630204.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            15667..16710
                     /locus_tag="J8S10_001619"
     CDS             15667..16710
                     /locus_tag="J8S10_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAZ9630205.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(16947..17828)
                     /locus_tag="J8S10_001620"
     CDS             complement(16947..17828)
                     /locus_tag="J8S10_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAZ9630206.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            17987..18715
                     /locus_tag="J8S10_001621"
     CDS             17987..18715
                     /locus_tag="J8S10_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HAZ9630207.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            18871..19188
                     /locus_tag="J8S10_001622"
     CDS             18871..19188
                     /locus_tag="J8S10_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAZ9630208.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            19181..19789
                     /locus_tag="J8S10_001623"
     CDS             19181..19789
                     /locus_tag="J8S10_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HAZ9630209.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            19805..20635
                     /locus_tag="J8S10_001624"
     CDS             19805..20635
                     /locus_tag="J8S10_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HAZ9630210.1"
                     /translation="MRLKHFLITGIGLMLTGGLLAGATYTLGAQKSLTWDNGPRLIDM
                     VTETKKIKDANKIVIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKK
                     STGAIISLEDTSAQITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSF
                     NEFTGGTITAKDELGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSL
                     HEMENSGYTIQTSGESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD
                     "
     gene            20773..21261
                     /locus_tag="J8S10_001625"
     CDS             20773..21261
                     /locus_tag="J8S10_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HAZ9630211.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            21312..22184
                     /locus_tag="J8S10_001626"
     CDS             21312..22184
                     /locus_tag="J8S10_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HAZ9630212.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            22360..22722
                     /locus_tag="J8S10_001627"
     CDS             22360..22722
                     /locus_tag="J8S10_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAZ9630213.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            22731..23483
                     /locus_tag="J8S10_001628"
     CDS             22731..23483
                     /locus_tag="J8S10_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9630214.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            23497..25299
                     /locus_tag="J8S10_001629"
     CDS             23497..25299
                     /locus_tag="J8S10_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9630215.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            25576..26616
                     /locus_tag="J8S10_001630"
     CDS             25576..26616
                     /locus_tag="J8S10_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HAZ9630216.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
BASE COUNT         8486 a         4638 c         5391 g         8112 t
ORIGIN      
        1 tttgatcgga tgtatttatc ccttttgcct aagcacgtaa aagcttgtat ctatgataaa
       61 taaataaaca tagcaaggta aaccagccaa tcaaagtaag agaaagaatg aaatagaaat
      121 agattggcgt ttgataatga agcgtgagct cgttgattcc tttttgctgc ttcacgattg
      181 gggtcccgat atctgttact tcataatcag tcaatgtttt tccattttgc tgtagcacag
      241 tccgatcgta gacgataaca gggatatgaa cagttttgtc cccagtgttt ttccacttga
      301 ttgtcaaaag accgcctgga tgtgttttta taaaagttgt ttcgttttct agtatttctt
      361 cgttataccg gtcgtattta ttgtcttttg tctccttata gattggcaga tagtcaggtg
      421 tggttttttg gaaaacgaac aagctggtag acatatcttt gctgaagaat gttttccttg
      481 cttcttccgg cgtatcgaat agataagtat gtcgactgac aaatgtttca ttttcccact
      541 tttccagatg ctggtataag ttctggatcg tctgtgctga aaaaataaga atgccaaata
      601 tacttaaaag acggaaccac ttttgttcag accactggtt cagtgaaagg gcaaggtaaa
      661 gtagaagcaa tagcgtaaat ggcacgaaaa atcgaaatgg aaactggatc aaactaataa
      721 aaggcacatt tttttcgatc aatgtcgtcc atggaatcaa gctagtagaa agaaaaaaga
      781 aaacaagact tgtgtacaac acgatttttt ggaataaggt gttcttttgt tgaaagaaaa
      841 taaaaagcaa aaaacctgat aatatcaata taggaaaggc cttagggtaa tggagccaat
      901 aactgccatc cagatctatc gccttttgac tcatttctct gttaacaaag ggaggaagaa
      961 tcttattccc actgtaaaca atagctaatc ctgcccaaat atttgctgtc agaacaaaat
     1021 aaagcaagac cgacttaatc agttgaagca gtgcttttcc tttttcagtc tggttaaaaa
     1081 agtaataaag ataaaaaggg atatacatca aagctaacat gatcgaagac agtaaatgga
     1141 tctgtgtcat aagtcccact gagacagcga ctttgataac agggaacttt ttatgaagga
     1201 cgaaatcagc aatagggatc atacataaag gataaaaaca agtcccccag ctagtgaatc
     1261 cttggttgat agaccagtat tgaatagaat acgtactcat gaataaaacg gctactggta
     1321 cacttaccca atttcgaaca ttgacatatc tcagtaaaat cagcatagaa aatcctgaaa
     1381 taagataaag aatgaaattt gaaagaatct gataatgaaa ccagctacct gcaagcaaca
     1441 cgatcaatcc ttgtaaataa gcgaaaaatg ggccgtaaac ggcattcacg atcctgccac
     1501 tttgctggaa tccataaagg gaaggaaaat aatggaaatc cccatattta atttgttgcg
     1561 cggcatcata gaaccgattg taatggaatg gggcatcagc acccaaaatt agtttatgtg
     1621 tgaataaatg aggcatgaga aatgccaaag caatgaaaaa aattgctaaa aatgggccat
     1681 attttttcaa ttgtcgaact cctttgcaaa ctttagataa attcatcata tatcctatgc
     1741 gagaggtagg caagaaatta gaaaattcat gaaaatattt atgaatttta caagaaaaac
     1801 ataagtgaaa gttctaagga gagaggatgc gacataagtt ttgttgcatc tccttgtttt
     1861 gaaacagaat ttttcttaat actcgaaaca aagtagcttt ttcatgacct ctcggtaaac
     1921 ggtgttcaat cagctgcttc tcggtaataa gctcactagc ctagaaaata tgagaagcta
     1981 ttttctgact agcgctctta ttactcaaag cataacgcag ttttcacaac ctcttcctta
     2041 aacggtgttc aaaagcttgc atctgcggta ataagcccaa cccaacaaaa aatatgagta
     2101 gctatttttt tgggctgtac ttattacttg atgcaggaca gctttttcac aacctcatcg
     2161 gctttcattt tctatttttt tcctgaaccc atataataaa agaaagaaca aaaaaacttg
     2221 caagggagga cacatgtgaa gcagagtaag caaaaacagt ctcgtcgact tttgtttcgt
     2281 ttgtttttat taatatgtat cgtcgtaggg ttactgatcg ctttatatcc attttatgtg
     2341 gattctttaa atagttttat tgatcaaaaa cgtatcgaac aagtacaaaa acggaccgca
     2401 gctgaaattg aagtgcagcg aaagaaaatg gaggagaaaa accaacgatt aactgaccaa
     2461 ggattcaatc ctggtactga tcctttcaat gaaaagaaca gaaatgaaag tacaacatcc
     2521 agccaattag aggaatggct gatcggaagt atcaatatac ctaagatcca attaaatatt
     2581 tcactttatg atcggctcaa tggtaggatc cttgaaaatg gagcaggcgt cttgcaagga
     2641 acctctttcc cgcttggtgg aaattcgacg cattcagtga tctctgctca cagcggttta
     2701 cctaatcgac ggttatttac cgaattagat cgtttagaaa acggagacac gtttattttg
     2761 actgttttgg gggagaaatt ggcttatcaa gttaaaaata tacaagtggt actgccagat
     2821 gacacgtctg ttctaacgat ttcagaagga gaagacttag ttaccttgct tacatgtacg
     2881 ccgtatatga tcaacacgca tcgtttgcta gtgacaggac atcggattcc ttataacgaa
     2941 tcggtaaaaa aagaagaagg aaaaggaaat caggaaagaa ccatgcggca atggtttatt
     3001 cttgcaggaa cgataatagc tgtagtcata ctgttagtgt ttatcggacg actaatctat
     3061 cagtatagat taagtaaaaa agtgcttgat ttttcattta ttattagtga ttcgtcaggg
     3121 aaaccggtaa atggtagttc attcattttg aaacataaga aaaaaacact tactagaaat
     3181 ggtgtgccgt tttcagtaca aagcgaccat catgggaaag tcaagctgga tcaattgcct
     3241 ggtggaactt atcgaatcgt ttcagctgat gatcctaaag ttgctgtttc ttttggtatt
     3301 agaaaagtaa aacaagagaa gatatacttt tttgaggggc gaaaacttgt aaaagagctt
     3361 caaaaaaatg gtttttattt taaaatcaat gaataagtaa ggagagaaaa aatgatccgc
     3421 acaacaacaa aattgtctgc caaagaactg gaatctgttc tatcgatttg gctgcatgct
     3481 aacttggatt ctcatgaatt cattccatca acttattggg agaatcaagt agaatctgtt
     3541 aggaaagctt taccagatgc agtgatttac ttagcagaaa tagatcaaga aattattggt
     3601 tttgctgggg tgattgatca gtttatcgca ggaatctttg tgaaaaggga ataccggcaa
     3661 caaagaatcg gtacgcaact aatgaaaaaa ataaaagaaa ccaataaaac actgactttg
     3721 acagtctatc aaaaaaatca atcagctatt catttctatc tttcacaagg ttttacaatt
     3781 caaacacagc aaaaagatga agcagtaaat gaggaggaac ttgtgatgaa atggaatcaa
     3841 aacgctgatt tttgatgaac agaataacga aataatgctc ccagcctaat tttttgctgg
     3901 gagcattatt tcattttgaa gtcactaatt taactgtgtg aatatgcagt tgttacaatc
     3961 tttgataaac ggtgttcaat cagctgaccc tcggtattag ctcaaaaaac ggcaaaatat
     4021 gaggaactat ttttccattt gtttctctaa tactcaggtc aaaacgctga tttcacaacc
     4081 tcttgataaa cggtgttcaa acggctgctt ctcggtaata agcccactag cctagaaaat
     4141 atgaaaagct attttctaac tagcgttctt attactcaaa gcataacgct gatttcacaa
     4201 cctcttgata aacggtgttc aatcagctga ccctcggtat tagctcaaaa aacggcaaaa
     4261 catgaggaac tatttttccg tttctttctc taatactcag gtcagaacgc tgatttcaca
     4321 acctctcttt cacaacctta ttttactcgt ttataatttt catcgaagta ttttccgcta
     4381 cggatatcat ctggcattcc atcgtatggt tcttcgctaa taacatcttc attgtctata
     4441 cctgcatcac ccatataagt gatcgtagca aattcaggaa caagtaattt tggataagtt
     4501 tcatattttt cacgagctgc ttccatttct gcgatatgtt cgttttggaa agtaacagtg
     4561 atttctggat gttcttcaac ccatttaggg aaaaagatca ttccgtgaag tttcttttca
     4621 tttggcataa agtccaatgc cacgtctgtc cctgttggct ctgtccaagt gattttgaat
     4681 acgccgtccg tcaatttaac gatatcagct tcttggtctt ttacccaacg gcctttgacc
     4741 attccgccat ggatacggta atcaacagta tggtcatttt tggcatacca ttcatattcc
     4801 caaccattgt catacgtata gataaagtga gttccaataa aatcttccaa ttctttaaat
     4861 tctttcatgt ttaagcatct ccttataaat taaaacatgt aataaactac atgttttcga
     4921 ttactcattt atgatagaat ggatttaaag atttgtcaag gagggaaaac tgatggcaag
     4981 aaaaaataca cttcgatata ttttgttagg gttattaagt aagaagaaga tgacaggata
     5041 tgaattgaat caatcgttca aaaatgaaat aggagaattt tggcaagcaa aacatagtca
     5101 gatttatcct gaacttgcaa aaatggaaga gcaaggaatc attcagcatc aagtagagat
     5161 cacaggtgaa aaattggaaa agaaagttta tgaattaaca gaagaaggga aggaacaatt
     5221 ggcagagtgg attcatacac ccaccaatga actaccggtt aatcgagacg aatttgttct
     5281 gaaattgtat ttcgtcaaag acgtgaatga tccggcatta gtagaaatta ttcagcagca
     5341 gcgtgacctt catgaagaaa aacgacttca tctattagag cgaaaaaaaa cgatctttcc
     5401 tactgaaaaa gaaaaacatg aaaattacgg acactacctg attttagcgc atgcgatcaa
     5461 tcgggaaaca gaatatgcaa attggctaac agatgtatta gaagaaagta accgaaaaaa
     5521 ataaaaaaat atccgaacag tgatggagaa ttcctttcta tatgaaagaa acgcagatca
     5581 ccgttcggat attcttatgt tcaaacaggc cttttttcaa gtatttatgt agcatctact
     5641 tattaaaaag cttggtactt aggagattag tggcgtttag agttctttta acaactgttc
     5701 gtagtcagct ttttcatcga caggaaggag cttgtaagtt aattcgtctg tctcgttgtc
     5761 atgaatgatg tacatcttag cattctcttc tttgaagtta ccgatttgta aaatcgtata
     5821 gcgttcgtcg atcaattcga tatctttgat tgcttttgaa aaaactttac ggacatggtg
     5881 cattttcttt tggcggattt ctgccttttc tgcagctttt gacaaagtaa atccgtcatc
     5941 taaatatttt ttgatcagtt ctacttttat gactgtaggt aaacgatatt ttctaggaca
     6001 attcgcatca gcttcgatcg aacgaatgaa tcccttttgt tcccaatacc ttaattgacg
     6061 tggagacaca cctacgatat cacttaattc actgatgcca acaaccaatt gatcattttc
     6121 caacaaacgt ttaagggaag ccccaaccat ttttgtcact ccttttgtcc tcttgcttcc
     6181 cttaattata tccgtattaa cttatgtgtc aagtaggttg acaaatagcg aatttaggac
     6241 taaagtattc tagtagtttc agaaaaaatt cagaaagaag gagaaatatg agtaacaacc
     6301 aacccgtaga tatttacgga aaaccatata atcggacact tttagttgtt gtcttattaa
     6361 ttggtacatt ttgtaccgtt ttgaatcaga ccttattgac gacagctttt cctacattga
     6421 tgaaagcttt cgatatttca gcgtctgatg tgcaatggtt aacgactggt ttcttgctag
     6481 tcaacgggat catgatccca ataacagcat ggctgatcaa taaattcagt tcaagaaatt
     6541 tatatctttc tgccatgacg atctttttga tcggaacgat tacttgcttt acagcaccta
     6601 attttagtac attactaatc ggtcgtttga tccaagcttg cggtgtggga gtatcgatgc
     6661 cattattgca aaatatcatg ctatctattt tcccgccaga aaaaagagga tcagcaatgg
     6721 ggatgtcagg gatcgttatt ggacttgctc ctgctttagg ccctacatta tctggttata
     6781 tcattgataa ctaccattgg cgtgacttgt ttggtatggt actgccaatc gttgttcttg
     6841 tcttggtttt agcattcttc ctaatgaaaa gtgttattcc attgtcaaat cctagcattg
     6901 atattttatc cgctatttta tcaacgattg gattcggtag tttactttac ggattttcta
     6961 gtgtaggaga tgacggctgg ggaagcttga aagtaattgg tttcttagtt gttggtgtga
     7021 ttttcatcgc cttgttctca tggcgtcaat tacatttgga acatccattc ttggaacttc
     7081 gtgtattcaa atcatctaca ttcacgattg cagctgtttt agctggtgta acaaatatgg
     7141 cgatggtagg ggcagaaatg gtcgtaccat tgtatattca aaatattcgt ggagaatcag
     7201 cattccattc tggcttgatg ttgttgccgg gtgcattgat catgggggct atgatgcctg
     7261 tgacgggtgc gattttcgat aaatacggcg cgaaacgttt agccatcaca gggatgttca
     7321 ttttgacagc ggcaactgca ccatttgctt tcttgacaaa aacgactcca gttttatata
     7381 tcgtgatcct ttatgcgatc cgtatgtttg ggatctccat ggtcatgatg ccggtaacga
     7441 cttctggtat gaatgcattg ccaaataact tgatcagtca tgggacagcg gtaaataata
     7501 cattccgtca aatcgcaagc tcgattggta cagctatttt gatcagtgtg ttgacgaatg
     7561 tgacaaaagc aaatatccca agcaaatctg tattggataa tacgccatta gcttataaag
     7621 atcaggcaat caatgccaca ctgtcaggtt accatgccgc gtttatcgta gcgatcatct
     7681 ttgggattct tggctttatt attgcctttt tattgaagaa aaaagaacct gttctaatga
     7741 aagcggggga taatgcatga ttattggagt tttgattgtc agcttgcttg cttttgcttt
     7801 aacgaacgtg ttcgctaaaa aaacatggca aaccttttta tctttgattt tcggactaat
     7861 cttcgtcgct tcactaagtt tgatcgtcgc taatttgtcc aatcactttg gaatggaaaa
     7921 agtaacggaa acaaaaacag aaaaaattgt ttccagtgct gattcccaag gagcagatat
     7981 gcttttgtat aaagctttag ggaatggaaa agaaaaagtg tatctttacc gaacaaatga
     8041 aaaacaagaa aaaccaaaag caactggtac ggataacgaa acaaataaag tagaaaagac
     8101 agacggcgat gctgaaaaag tgacgaaaac tacttattgg gaatacaaaa acgacatgta
     8161 taaattctgg ttcaatattg ctgataacaa tcacgaatat gacagccgag tgaatacatt
     8221 caaaatccca gagacatggg tagaattaag tacggaccaa gcagccaagt tagctgaatt
     8281 agtgaagaaa cagcaaagta cgatggaaag tgaagcaaaa gcttatgttc aagacggtat
     8341 ggtaaaagca atgactgaaa atccaaaaat gagcaaagca gagcaagaac aacgtacgaa
     8401 agccttagct gctgaattcc aacaacaagc attcgcaaaa ttagtgaaag aagcaaaagg
     8461 cgaataatat tttgaacacc atgtaggagg ttgtgaaaaa gctgctctgc atcaagcagt
     8521 aagaacaatc agataaaaat agcactccat atttttcatc tgattgggct tagtgccgta
     8581 gatgcaagct tttgaacacc gtttaaggaa gaggttgtga gcctgccgtt taactctgag
     8641 tcacaaggag caatttcaaa aaacagcttc tcatgtttgt tgactattgt gacttgtgac
     8701 cgaggagttg gcaggagaac accgtttatt cgaaaaaagg aactgcgaca agacttttgt
     8761 cacagttcct tctttttttt gctatgctat actagatgta aaaaatagga gaaataaaat
     8821 gagggaaatt tattcttttg aatcaaaaat ctatgcttcc gaagtcggca agggcggggc
     8881 atatattatt tttccgtatg atataagaaa agaattcggt gctggaagag ttaaagtcca
     8941 agcaactttt gacaatgtgc cgtatgaagg cagtatcgtg aatatgggcg tgaaaaatcc
     9001 agatggttca gtctgctaca tccttggact acgaaaagat attcgtaaaa acatcggaaa
     9061 agaaatcggt gatattgtag cagttacagt gaagcaaaaa taaaagaggt tgtgacaaaa
     9121 gacgtgtcac aacctcttga taaacggtgt tcaaaagcca gtttctcggt agtaagtcaa
     9181 atttatgcaa aaatgtggaa acccatgttt acaaaatttt tcttactact cgaaacgaag
     9241 cggctttatc acaacctctt gataaacggc gttcaatcag ctgtccctcg gtattagctc
     9301 aaaaacggca aaatatgaga agctattttt ccattttttt ctctcatact caggtcataa
     9361 cgctgatttc acaacctctt ctttcataat ggtttttcac catctttata ataaactggt
     9421 tatttgatat ggaaatctat tttttccaac caatctaaaa tcttgtaacc taactcttct
     9481 gacatcggaa aagaggcgtt gatttgtgca ttggagatat ggtcaacatg gataccggaa
     9541 gtgatcgtac aacttcccgg aacggcagtt ttgatgatca cagctatttt ttcggctaag
     9601 acatcgtctt tatggaaccg accatcgtgg ctagggaaac gtacagtttg catctctgta
     9661 tcacgagaaa atgtagtgac tgttccgata tgtggtgtat ctccgcctgt taaagtgatc
     9721 aataagtctt taccgattac tttaacagca gcttggatcg tgaaacctag tttggttact
     9781 tcaactatcg tttctttttc catattaatc accctgccaa cgttttgaat gctcatttac
     9841 aatttcaaat tgatccaaaa gtttcattgt atggtgatta acaagatctt ggatcgtttg
     9901 aggctgatta taaaaagcag gaattggtgg tatgatttgc acacctagtc gtgctaattt
     9961 agtcaagttt tccaagtgaa tggcatttaa tggcgtttca cgaggaacaa tgactaactt
    10021 tcgttgctcc ttcattgtta catcagcagc acgtgcaatc aggttgtcgc ctaaaccaac
    10081 agagatacct gcgactgttt tcatacttgc cggtacgatg atcattccat cggtcaaaaa
    10141 tgatccgctg gcgacagcag cacctaaatc tttgtttgaa taatggtaat caaacaggct
    10201 ttcgaattca gttagtgata agtcggattc cagctttaag ttctgttttg cccatggact
    10261 gatgattccg tgtgtttcta tcatcggata ttcttttagt ttcttcacta ggttgatggc
    10321 ataaatggtg cctgaagcgc cacttacacc aatcacgatt tttttcttcc gttgtgccaa
    10381 ttgttccatt ttccgcactc ctttttatga tgtcaaaaca gttgcagatc attcattatt
    10441 tcaaatattt ttcccaatct tctacttctt ggaattttgc acgtacaaaa tgttctttca
    10501 tatcgaaagg aactgtaccg tcaaagatag tttttgcact tatcccacgg aaacgaatag
    10561 agccaggatt atattctggt aattctgatg ggtccaatgg atggttcctc attcctggga
    10621 tcacgatgat atctttatct ccttggaaac gagtgttgaa agtccaaact acatcgttca
    10681 tgtcgaaaat atcaacatct tcatcgacta aaatgactgt cttcaattct ttgaaggctg
    10741 ataaagcaag aatagctgct tgacgctgaa taccttcatc cgcttcgttt tctttacgga
    10801 tttgcatgat ggtcatcaat ttaccaccac ctgcaggagg attgtagaca tttactactt
    10861 ttcctggaat agctttatcg accaaggcaa gaatacttgc ttctgtagga ataccggcca
    10921 tagatacgtg ttcttcactg ggaccaatcg ttgtttgcat gattggattg tcttttcggt
    10981 gagtaactgc tttgactttc actacttgta cagctggatt agcatcccca gtatagccag
    11041 gaaattctgg cattgctttt cctgagttcg tgttgatatc ttcttgcatt gtttcatttg
    11101 gcatgatttc tgcttcaatg atgaattcag cacgagcaat acccacttca tcgactgcta
    11161 taccatcaac gatttgaata ggttcgttac gcaaagctcc tgcacaccat agttcattgt
    11221 agccaagtgg agtggtaggt ggttcgaaag tcgtgccaat ggcaattgct ggatctaaac
    11281 caatattgat agtgataggc attggtttat tcaaggcttc gaattgtttt tggaagtgac
    11341 caatgtggcg tccgccaggc atgatgtaca taccgatcgt atctttatct tctagaacca
    11401 tacgatggat cgttacatcg ctcattgttt tttctggatc tgatcctaag actacaccca
    11461 ttgtgatgta tggaccagca tcttcaggag tatttgtagg tgcaggcaaa atgttgcgaa
    11521 tatcgaagtc tgcatcggta gctagatgaa cgacttcttg tgctggagcg tctgctttgt
    11581 ctactttcac aggtttgatt ggattttcta cagcgtcttt caagaaacga ccaagtgttc
    11641 gataatcatg gtgcaaaatt tcacctacac gtttacgact agccattgtt ccgatgttca
    11701 cacgtgtgcc ggggaaacct ttgatattgt tgaaagtcat agctggtcct tcttgagtcg
    11761 gacgttttac tgtaccgcca gcaccgatat aacggtaaac accagataat tctgcttcag
    11821 gatcgatttc aatatctgtt tcgtgatatt gacctggaag tgtttttagt tcttcgatga
    11881 cttttcttaa atcatacggt tgatctgtca tgagagattc ctccttagtt gtctttacct
    11941 atctatagta aaaggtgaaa aagaggaaaa caattcaact tgttcggtaa agtattctac
    12001 aatggaatgg atgcgttttt ttgataatag aataaactat gatatactta tcactaaaag
    12061 aaagcgcata cttagtgttg gaggaaggaa agtgaaaaaa atggaggagt catttcctaa
    12121 agcagtaaaa gtggaaaata tagcgaatat tttgaaagtt acatttgaaa acggagaagt
    12181 aaaatacgtg aaatctcatt ggacagaaga gataaccgat gccttgcaat ttggaaaaaa
    12241 aggaagagga aaaagaaaaa atcttctcgc actttctcgt aatatgtgga ttgggactga
    12301 agtaacgatt gaagcagatg gaacagtatt cataaatgga aaagacaggt atacgccaga
    12361 agagttgtgg tacaaaggaa agaaaagtat accagaatta taaaaaataa ttaaaaaaaa
    12421 cagcgcgaaa caaggaacat attacttcct cgtttcttgc tgttttctac tatttcagcg
    12481 ctcttatgac tcaaatctaa atgtggttgt cacaacctta ttctgcacgc aaagcgatag
    12541 cggcgtcttt tttcgctgcc attcgtgcag gaagatgacc gccaagcatc gtcaatatag
    12601 tagagacgat cactagaata atcgcatgga caggatttag ttgagcaaca ttttttagat
    12661 ccgtcatgtt gtataagatg ctattgatag ggaacgtagc tagccatgca ataaacacac
    12721 ctaatatccc agaagaaata cctaaaatac acgtttctgc gtcaaatacg cgagtgatgt
    12781 cttttttacg tgcacctaaa gcttttagta caccgatttc ttttgtccgt tcaatcacag
    12841 atgtataagt aatgatactg atcatgatca tacttgttac taaagagatc cctgcaaaag
    12901 caataaggac ataagtgata gcatccatca atccgccagt cagttcagtc atcgttccag
    12961 ctaaatcagt ataaatgatt ttatcttcat ctgatttgcc tttattgtaa tcatctagat
    13021 aatccaagat cttttctttg tcttcaaaat tgttcggata aatcatgata cttgaaggca
    13081 agctgtctcc acctaaataa ctaagcaatg tttgtttggc attttcgtca actttttcag
    13141 tagttaagac atttacacca ctgtctcttt gagctttgac gatttctgat tctttgtttt
    13201 cgttgacgat ttgagtcgtt aattgatcgc tataagcgat tcctggagat aagagattca
    13261 ttgtagaaga agatttcacg cgtaggatcc ccgagatctt caattcatca gaagcattct
    13321 gatacatcgc atcataatct gtattaggga taaaattccc agttggaagt tttgtatagt
    13381 aagtattgtt gtttactaat ttgaatgttg taccaacgat atcatcaaaa tcaagttttt
    13441 cgtcttcttt cacatcaaat ccaagattct tcaatgcgtt gatattagta ttattattgc
    13501 cgtctacgat cagcacgaca tctgttgctg aggctggata acttccggca agtaaagaat
    13561 aattgtcttt taaaaagttt tctttgctag tgtcaagctg tgtagggaaa cttgacactc
    13621 ccacacctgt cattgctgac atcgtactag ataaagaaag agattccgta tcaggatttt
    13681 gattcgagaa gctgacaggc tgtactttgc catttacatc acgtaaaaga ttgattcctg
    13741 tagtacgggt aaatccgata ttattactta agttaggatc gatgtctgtt acgtaatcga
    13801 cgtatgtttg atcaatctta ttcgtgtgct gtgctttatc ttcttcgctg acttttgcag
    13861 taatcgtttt gctgtctgga taatccgctt tgcttgcacc caatccggca tcgtcacgag
    13921 tctggttagt cgttacctta gaaatagtaa tcggaaattt cgccatcgtt tcagcttgcg
    13981 tgttatcgat ttgtttttgg aatccagaag aaagggacag aacgatcgcg attccgatga
    14041 tcccaatact ggaagcaaag gaggtcaaga aagtacgtcc tttttttgtt cggatattgt
    14101 tgaaggaaag ctttaacgct gtccaaaaac tcatctttgt tctgcgtaag ttaaattgat
    14161 catcttttgg tcgttcgatg tgaggatggg aatctgttaa gatcttacca tcagaaaatt
    14221 caatgattcg atctgcgtat tgatgggcca gttcaggatt atgtgtgacc atgatcacta
    14281 atttttcttt cgataactct tggatcaatt ccatgatctg gatacttgtt tctgtatcta
    14341 acgctccggt tggttcatcg cacaaaagga tatctgggtc attggctagt gctcgagcga
    14401 tggccactcg ctgcatttgt ccaccagata actgatttgg ctttttatgc atatgatttg
    14461 tcaagccgac tcggtgcaat gcatcttctg cccgttttcg tttttcgtct ttagaaacac
    14521 cacttaatgt catcccaagt tcaacgtttt caataatgcc tagatgacca atcaagttgt
    14581 aactttgaaa aatgaaaccg atagagttgt ttcggtaggc atcccagtca ctgtccttaa
    14641 agtctttagt agactttccg ttgattacca tatcaccgga atcataatta tctagtccac
    14701 caatcacatt cagcatagtc gttttaccag aaccactagg acctaaaatc gctacgaatt
    14761 ctttttgtct gaaagcgaca gacacaccat ccaatgcttt ggtggtggtt tcgccgactt
    14821 tataatattt ttttatatct tttaattgaa gcataatcac ccttctcccg tattgaaata
    14881 ttcggtatac taataagtat atcagaacaa tgatcgtagt atacgaaata aatgttaact
    14941 gaagatgaac tacaagaaaa aatctagaaa tttttcaaaa aacagaggga gatcaatgaa
    15001 tcgtatttta gtagtagaag atgatccgca attacagttg ctttaccgtt ctgtgttgga
    15061 acgagcgggc ttttcagtca tcaccgcatt gaatggagag gatgcgctga aaaaactaga
    15121 agcgacacgt atagaattaa tcattacaga tatcatgatg ccgaaaatgg atggctatga
    15181 cttgctagac tcattacgta gcaccagatt tgacacacct gttctaatga ttacggcaaa
    15241 ggccgatttt gaggataaga aacgcgggtt caaattagga gcagatgatt atatgacaaa
    15301 acccatcgat gtcaatgaga tgatcctacg tgtggaagca ttgcttcgac gttcaaagat
    15361 caattacagc agtagcttga taatcggaca aacaaaatta gagctagatg cttatacagt
    15421 gttacaagat cagcattcgt tgattctgcc tcaaaaagaa tttctgcttc tgtataaatt
    15481 actgtcttat cccaacaaga tcttcactcg ccaacagttg atggatgata tttggggatt
    15541 agatacgaat acagaagaac gaacgatcga tgtacatatc aaacgtttaa ggacccgttt
    15601 tgaaaagacg gaagattttc aaatcatcac agtacgggga ctaggctata aggcggttat
    15661 ttaaagatga aaaaaaagct attttcacaa ttatggatct attttgctag tattgtcttc
    15721 atttcgatct tagtgacact gctgtgtttt ctcggtttta ttttcttatt gtctcgacat
    15781 tctatctcgc ctgctgaatc ggctggaaaa ccaacgttat acccgttatt cgtctttgcg
    15841 gggttcagta tggtcgtggg tacaggaata tcgatttttg ttgggcggcg tatcctgcat
    15901 ccaatcagtg cgctagggac aaatatgagt ctggtagcaa cgggagattt ttcgattcga
    15961 atggatgaac agcagaaagt agcagaagta cagcaactgt ataaagattt caacgttatg
    16021 gtccaagaac tcaatagtat cgagacactg aggaatgact ttgtgtccag tgtatcccat
    16081 gaattcaaaa caccactagc aacaatccaa ggatatgttc aattgttaca agccccaaat
    16141 ctctctgacg aagaacgcca aatattttta tatcggatta tcgaaagtat cacgcagctt
    16201 tcacaattaa cagagaacat cttaaaattg aacaaactgg aaaaccagcg tatccaactg
    16261 gaaaagaaag agtatcgatt agatgaacaa atcagagaag taatcgtttt ttttcagcct
    16321 aaatgggaga aagaacagct agaattggat atcgaacttg ctgcagtaaa ttacacaggc
    16381 aatgaagagt ttttgtacca agtgtggctg aatatcatgg ataacgccat aaagtacaat
    16441 caaatcaatg gacagattca tatcaaacta tttgagacag ccacagagat tgtactggaa
    16501 gtgaccgatt caggtgtagg aatgaatgaa gagaccagag atcgaatgtt tgaaaaattt
    16561 tatcaaggag atacaagtcg tcaaatttct gggaatgggc taggactttc actggttaaa
    16621 aaaattctag aactgcatga tggacgtatt gattatagca gtatcgaagg agtaggaacg
    16681 acagcaatga tacggttaag taaacaatag gaaaaagaat aaaaccccta aaaattctat
    16741 tgaaggtttt taggggtttt tagtcgtttt tttgtgatta gggaaatgtt cttacggttc
    16801 ttttggcata aaaatcgctg ctttcttatt gaactacgag aaatgttaga ggtgtcattg
    16861 aaacaaggac atgatgcaag aaagagagcg aaagtcatgc gtcgctctct ttttttgggt
    16921 ggatagatgg acagaaaatg tagggcttag ttttcttctt gatttaaata ctcccaaaat
    16981 gtatctgaag ccaaagaatg ctcaccgact ttacgagtaa atgcaagata actctctgtt
    17041 gttggagaaa tagggagaat cacagtattt tcttttaata gattcttgac tgttttttcc
    17101 ataacaatag caatccccat gtcatttgca atcatattga tgatcaagtc gattcttgct
    17161 cctttataag agatttttgg ttcaaatcca gcttcgcgac acagatctag tacaggttga
    17221 tacaagttcg tagtggggcc aaggagcaaa aagttctcct ttttcagttc gcttagatcc
    17281 aatttctttt tactagctaa aggatgattt ttaggtagaa ctgctacaaa atcgtctgtt
    17341 tcagtaggca accactcaat cgaacttggt ggggcctgga aacttctagc aaagtggatc
    17401 gtgtcactat gttcattggc gtcattgtaa gttaattcga cactttccac ttctttcaac
    17461 tggactgtaa attcaggatg gcgtttcaaa aactcggtga ttttggaaaa acctttataa
    17521 ttgatcattg tcggtatcgt taagatattt aatgaaagat tgttgtcttt cgtataggtt
    17581 tcaagcactt cttgcatagc atggtattgt tctacgacat tttttacata tgggagcaat
    17641 aagcttccag cttcggtcaa ttcgattttt ctatgggcgc gttcgaataa tttgacgtct
    17701 aattctgttt ctaacgaaag aatctgttta gaaatatttc cttgggtggt gaattgtcga
    17761 tcagcagttt tggtgaaatt cattgtttcg gctaaatcaa gaaaaacttc gaatttatgg
    17821 atatccatca tattcctcct acttattcca ataaagaata ctttaacaca aaaaatgaat
    17881 tggtgtaatc ttctctgtct gttacaatct ttcttgcagc gaaagcaata attacagaaa
    17941 tttttctgat ttttttcgct tcgtagaaaa agagaggagt tttttgatgc caactggagt
    18001 tttgatcaat gtaggttccg ttttgtttgg cggactaatt ggcggattag taggaaataa
    18061 attaagtgaa cattttaaag cacagctgac gatggttttt ggtgtgtgtt cgatggggat
    18121 gggaatctat tccattgcgc cgatgaaaaa tatgccggct gttatttttg ctttagtgat
    18181 aggaacagcg attggtttga ttgttcattt aggtaatggg ataaataagg gggctgcgct
    18241 gatgcaagta cctatttcta aaatcttccc tagtgaaaag cttggtatga cccacgatga
    18301 atttatcagc acattagtga cggtcattgt tctattttgt gcaagtggta cggggatcta
    18361 tggaagttta gattctggga tgacaggaga cagtacgatt ttgatttcta aatctgtcct
    18421 tgattttttc acagcagcta tttttgcgtg taatttaggg tatgtcgttt ctgtgatagc
    18481 aattccccaa ttcattattt tttatatttt gttcttattg gcaaaattta tttatccatt
    18541 gactacacca gacatgatct tagattttaa agcttgcggc ggattcttga tggtcgctac
    18601 cggttttaga atgatcaacg tgaaaatgtt cccagtagct gacatgatac ctgcaatgat
    18661 cgttatcatg ccactgagct ggatgtggac aaattggatt atgccactgt tataataaaa
    18721 atcaaagaga agccattttt tgctgactaa aaaggatcaa atcttttagt cagttttttt
    18781 gtatttgaca aactgatttt gaaactatat tatatgttgt ataatataga ttgaaataaa
    18841 atattacact tgagaataga aggtgacgta atgcacatcc agattccaac tgttcttctt
    18901 gatggtactg tgctagcagc attaagcaag gaagatatgt atgggtatgc cttaacaaaa
    18961 atcgtacaag aaagtctctc tgtcagtgaa tctacactat atccggtttt gagaagattg
    19021 aaaaaagaag gatatcttga gacctatgat gaaccttttg aaggcagaaa ccgtcgatat
    19081 tactcgttga caccaatggg aagtcgtcat ttagaagaaa ttattgatga atggattgtt
    19141 tttcgagatt ctttagaccg gttattggag gagagcacaa atgaatgaat atttgaatga
    19201 agttgtggat catcttcaag aaattcctga agacgatcgt tttgatttga tccagtatta
    19261 tgaggaatat tttttagatt ctggaaaaac attagatcag atcattgatg aatatggtac
    19321 accaaagcag tttgccttaa aattaaaaat cagttacttt tcagaagaag aacaagcaga
    19381 aaacgagtta gtgaaaaatc caaaaagaca aattcgcctg atttggttaa tcattatcgg
    19441 tttatttgct tctcctgtcc tcattccact agcactgggg tttatattgg ttattggggg
    19501 actattggtt gctttactag cgctcatttt tagtatctat gttttatgta tcagtatctt
    19561 aggtgttggc ctattcatga tcatctcagg aatcagtgtg tttggacaat cgattctgag
    19621 tggattattc tttatcggtg tcggtctgtt cgccacagga agcgcagtat ttatttcgcc
    19681 actgttgctg aaaggaacaa aagggctttt ttatgtcatg atgaactttg ttaaatggat
    19741 gggacgacgt tttattacaa aaagagatct gcattcagcg ggcgtttgaa ggaggacaca
    19801 taaattgaga ttgaaacatt ttttgattac cggtattggt ctgatgctta ctggtggcct
    19861 cctagcaggt gcaacttata cattaggcgc tcaaaagagt ctgacttggg ataatggtcc
    19921 tcggttgatc gatatggtta ctgagacaaa aaaaatcaag gatgcaaaca aaatcgtcat
    19981 ccatgcagaa aatcaaacag tttcggtcat acgcggattg gattttgaga taaaaacgac
    20041 ttatgataag acagaaaagc cagaaataaa ggagaaaaat ggcgtgttga ctgtgaatgc
    20101 agtcaaaaaa tcaacaggtg caatcattag tttagaagac acaagtgcac aaatcactat
    20161 tgttgtccct gcagatcatg aattatctga attgacaatc gaagggaata atagtgcaat
    20221 tgatatcaac gaagtatcaa tcaaaaaagt gaatactaag acacatgatg gctgggtatc
    20281 gttcaatgaa tttacaggag gaacaataac tgcgaaagat gaattaggct cacttcgatt
    20341 agatgaggcc aatgtggata acttgatcgt cacaggtgaa aacagcaact tccatctaga
    20401 agacagtttg atcagcaaag aaggaaaagt catcctaaac ggtggcaatt tatctttgca
    20461 tgagatggaa aacagtggct atactatcca aacgtctggt gaatcttata ttgaaaaaga
    20521 ctaccagcca ataacaaata ctttgttaga acaaggacag aaaaagctaa agatcactgc
    20581 taaagacaca tcgatcaata ttacgacgga tcaagaggac aatgaaacag attgatcctg
    20641 tactcaactg gatattttaa gaaaaaacag caaagatcct tccaatcttt gctgtttttc
    20701 atcgcttaac gcacataact atagtaaaat aagaaagaaa atatctaaaa agaaaacagg
    20761 gtgaaagagt atatgaaggt agaagaaggt caaagagaaa agttaaaaac agaaatggaa
    20821 agattacata cttatatcac tcaactaagc caaaccttct atgatccaga caaagaaaaa
    20881 gtgatggtta attacccgaa caattcagaa ggtcgccaat tagagcaagt gtaccatgaa
    20941 gttttcaaac atttattgac ggtgaagaaa gagctggatt attattcttt accgattatc
    21001 gatacaggaa tattgaagta tgatgggaag aaggaacgat ttatctttaa atctgttcgg
    21061 gaagatttgc ctctttcagc agggatggat ctagaggtct tggtagaaga ctattttaca
    21121 gaagaaaagc actgggttcg aacaaaattg gattatttac cgcaggcagc cggagggaca
    21181 caggcaagcg gttggtacat cactgaagac aaagagttag aactagaagg tgtaatggcg
    21241 cgtattcgaa aaaaaaatta aaaaagtaac attagatatt tattgaagga taaaggagcg
    21301 caggaagtag catgagagaa aaaagagcat tttatatcaa tggttatgca gggattgtcg
    21361 gattggtcgt attagcttta gttggattgt ttttcttcta tttaggtatg tggcaagcga
    21421 aagtttgggc acttttttta agtatttttc tttggttgat cacgttattg ttgttaagtt
    21481 cggcaactgt agtcagtcct aatcaagcaa aagtaatttt gttttttgga caatatttag
    21541 gtacgattcg agaaaatggc tttttcctta cgataccttt ggcacaaaaa atgactgttt
    21601 cgttgaaagt tcggaatttc aatagttctg ttttaaaagt caatgatttg gatggaaacc
    21661 ccatcgaaat ctcagcagta gtagtcttta aagtcgttga tacagcaaag gcattattcg
    21721 atgtagcgta ttatcaagat tttgtagaaa tccaaagtga gacagccatt cggcatatcg
    21781 ctagccaata cccgtatgat acattcaatg agaatgattt gacgcttcga ggaaacacga
    21841 cggcagtgtc tgacgagttg caaaaagagc tgcaagagcg tttagcagta gcaggtgtcg
    21901 aagtaatcga aacacgcttg aaccatttag cctatgcaac agaaatcgct agtgccatgc
    21961 tccaacgtca acaagcaaaa gccattttgt ctgctcgaca aaccattgtt gaaggagctg
    22021 tcacaatcac tcaaatggcc ttagagcaaa tcgaagatgg acaagaaatc aatttcaccg
    22081 atgatcggaa agtccaattg atcaataatt tacttgtctc aatcattaca gacaaaggaa
    22141 cgcaacctgt tatcaataca ggcgacatga aagaccgtaa gtgacatact ttttgtaaga
    22201 taggaagaag gagtttagga cggattattg tcttgaactc tttttttagt tgttttaaag
    22261 aaaatgacaa aattgaaaga agaatgatag ttgattcgaa ggcagaattg ttcgcttttt
    22321 tctataatca gtatataaag taagagagaa ggggaaaaag tgaaaaaact tctgatcggt
    22381 ctacttgttt tcatcgttgt ggtacttgca ggggtgaaaa tcgcagatta cgtagttatg
    22441 ggtggagaag aatactatgt acaaattacg acagatggta caaaaacagt ttcaaaatca
    22501 gactctggac aagaaacagt caactataga tatatcctgc ctggctatac gaaagagggt
    22561 aaggaaaaag aactggactt caagggacaa ttgactcgac cgcttcgtaa aggagcatat
    22621 ttaaaaatca cctggaacaa aaataaaggt gtcacttcgt atgaagaagt cgaaaaaaaa
    22681 gacgtgccga aaacagcact ggaaaaacta attaaagggt agggaaagaa atgaacaaaa
    22741 tagtcgaagt acagaatgta acaaaagtat acggaaaaaa caatgagaaa aagacgcaag
    22801 cattaagcgg catcagcttc gatgtagaaa aaggcgaatt tattgggatc atgggcgctt
    22861 ctggttctgg taagtcgaca cttttgaata ttttatccac attagataaa ccaacagatg
    22921 ggcatatccg aatcaatcaa aaagatgtga ccacattaaa aggaaatcaa ctagcagatt
    22981 ttcgtgcgaa tgagattggc tttattttcc aagatttcaa tttattagaa agcttgacag
    23041 cacaagaaaa tatcgctgtt cctctttctt tacaaggcgt cagaccaaaa gaaatcaagc
    23101 aacgtgtcca aaaaattgca gaacgtttat ccatctctca tattttggaa agctatcctt
    23161 ctgagatttc cggtggacaa aaacaacggg tcgccgccgc acgtgcattg atcacacaac
    23221 caacgattct attaggggat gagcctacag gtgcgctgga ttccaaaagt gcccgggatc
    23281 ttttagatac gatggacgaa ttgaatacaa aagatcatgt atcgattctt cttgtgacgc
    23341 atgatccgtt ttctgcaagt tattgccaac gtattttatt catcaaggat ggcggtatcc
    23401 atcaagaagt gaaacgtgga gatcaaagcc gtgattcctt ctatcgagaa atactatcta
    23461 ttcttggaaa cttggaacag tagggggaga ttgactatgc tttggaaatt atcacttact
    23521 gggatcaaga gccgtttaag agactacttg gtgttattct caggattagt tatggcatct
    23581 gctatttttt acatgtttga atcaatggca agcaacgaag cttttttgaa aagtaatacg
    23641 atcgttgcgg ctacagttat cattttccga ttcggttctg ttttactagg gatcatcaca
    23701 ttcgtttata ttttatatgc aaattccttt ttgatgacga tgcggcaaaa agactatgca
    23761 atgtttatga tgctgggagc aaaaggcaga aaaatcgcac agatgatttt ttctgaaaca
    23821 ttcttagtag ggatcgcagc tactttagtg ggttcagctg tcggtgtagg attgacaagt
    23881 atcgtccacc gattattagt ggatcagtta gatctcaata tttcgcattt tacacctttt
    23941 agtattcacg ggttgttgat cactgttttg ttttttgctg ttttgttttt attagctgct
    24001 gttgtcaatg ctttttcgat tgtcaaaaaa ccgattttag cattgattcg tgcggatcag
    24061 acaccaacaa gaatcaagca gcataaattc ttgtttttcc ttgaagtagt actgggaatt
    24121 gcttttctag gctgcggtta ctatatgatg aaacacgtgg ggacctatca agtctttggt
    24181 ataggggtag ccttagttac gatcgtatta ggaacttatt tcattttcca ttctgtgatc
    24241 attttctttt tatcattact aaagaaatca gaacagattt cattgaaaaa attgaacaat
    24301 ttcacattgt cacagttaaa ctttcgtatt cgtgaatata cacaaatgct ctcaatggtc
    24361 gctatgctgt ttgccttggc actgggcgct ttgacggtag gattaggttt taaaaatgaa
    24421 attgcagact tgacagaaaa caattctgga tatgatctag tgatgaataa tcctcgggca
    24481 gaagatcagc aaaaaatcaa agaactttca ccaacacttt ctgcttctta tactcaaaaa
    24541 gaagatgcgg gaacgattta ctataatgca agtgaatttg cggctcaacc attgatcatg
    24601 ataaaacatg aagatggaac accgccgaag atcacgaaag aaaaagttcc tgctaaaaaa
    24661 atgaatgaac tgactgtaca agaggaactt cgaagctatg aattgccgga acagcaagaa
    24721 aaagaaatca aggtagtcag tcaatcagaa tttgatcaac tgaacttgcc acaatccact
    24781 ttacagctag ttcaggtaaa agacttccaa gcaaacctga aaccaatcga aacacttgtt
    24841 gctcaaaata aaatgaacaa tccatctttg caaaaagtag agtacagcaa ccagaaatat
    24901 gaaatgtatg aagtgtataa tggtctattc tctggttttg aatttatggg attcttccta
    24961 ggtttagctt tcttgaccat gcttgctagc tgtttgatgt tcaagatctt gtcaggaagc
    25021 aagagtgaca ttgctcgtta tgaaatgctt gaaaagatag gaacacgacg cgggttgctt
    25081 aaacaatcga tccgtagaga agtaggcgtg ttattcttag caccaggaat cttaggtgta
    25141 gtccatgtct tattcggatt acaaatgttt ggtctattca tgcaaaatcc atacaaagat
    25201 atttgggttc cgtttacgat attcttcgta ttgtatttca tctactatgt actgacgaca
    25261 tggttatata ctggaatcgt attgaaaaag agattgtgaa aaagctgtcc tgcatcaagt
    25321 aataagaaca gccaagcaaa aatagctcct catatttttc gtttggttgg gcttattacc
    25381 gcagatgcaa gcttttgaac accgtttgtt cggaaaaaga ggttgtgaca atatttttgt
    25441 cacaaccttt ttttcacggt cttttattag aatatagtaa attttttctc gttactcacg
    25501 gaataagctg ttaagaaaac ggtttccatg tatactggaa tcagtgcaaa tgaaagaaaa
    25561 gagggtgcaa ggaacatgga aatcaatgaa caaaattttg gcgaaaacta tcacttgatt
    25621 acgatcacga atcaaaatgg gacatctttg tctgtcagtg atcttggggc acgggttgtt
    25681 cattttcaaa caataatcga taatgaaaaa cgagagttga tcttaggttt tgatgaagca
    25741 aaagaatatc tagaaaaaga cccttatatc ggtgcttcaa tcggacgtat ggctggacgg
    25801 attacgaatg gcacattcaa attagatgat gaaacgttcg aagtaaaaac agacccggac
    25861 actggtcatt gtttacatgg tggtgcacct agctttgaag ccaagcagtg gcattataca
    25921 gtcatcaatg gtgaaaacga agcatcggtc attttctatc agactagccc agatatggaa
    25981 aacggatttc ctggaacttt agatgtagaa gtacggtata cgctgacgaa cgatgataca
    26041 tggcgagtga cggtccaagg gatcagtgac cgcaaaacag tattcaatcc tacaaatcat
    26101 gtctatttca atttaaccgg tgatccagca cagtcaatcg acgaacatat actttggttg
    26161 aatagccgat tatttgctac gctcaataaa gatacaacgc ctacaggaga agtagtttca
    26221 gtaagtggca cagcatttga cttccaacgt cctaaaaaat taggtgaggt ctttgccagt
    26281 gattttcgcc aatcaatgat agtgggcggc atcgatcatc catttttgtt gaaaaaacaa
    26341 tctggtttac taaatgctgc ggaattgaca agcccagatg aaaaagtatc gatccaagta
    26401 aaaacagatg cttcaggaat cgtgattttt acagcaaatt ttggagaaga tggaccggaa
    26461 atgcgcggga ataaattagt aaatcatggc ggtatcacat ttgagactca agaactgcca
    26521 ggagcggagc gacttgaaag ttttggagat gtcactctgg aacctaacca agtacgcgag
    26581 tttgtaacgg aatacaaaat aaatataaag aaatagaata aattaaa
//
LOCUS       DADQDV010000037        26537 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.037, whole genome shotgun sequence.
ACCESSION   DADQDV010000037 DADQDV010000000
VERSION     DADQDV010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 26537)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26537)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26537
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.037"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..1152
                     /locus_tag="J8S10_001631"
     CDS             <1..1152
                     /locus_tag="J8S10_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005236379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630217.1"
                     /translation="PSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSA
                     EAPKEKVETSGSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKED
                     IENFLAGGPSSAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPT
                     RKAIAKAMVNSKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALT
                     ATVKKYPVLNASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEI
                     NEKAKLAHDGKLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIV
                     NAEGEIVVGRVMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            1160..2566
                     /gene="lpdA"
                     /locus_tag="J8S10_001632"
     CDS             1160..2566
                     /gene="lpdA"
                     /locus_tag="J8S10_001632"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HAZ9630218.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            2728..3003
                     /locus_tag="J8S10_001633"
     CDS             2728..3003
                     /locus_tag="J8S10_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HAZ9630219.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            3009..3776
                     /locus_tag="J8S10_001634"
     CDS             3009..3776
                     /locus_tag="J8S10_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HAZ9630220.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            3944..5773
                     /gene="typA"
                     /locus_tag="J8S10_001635"
     CDS             3944..5773
                     /gene="typA"
                     /locus_tag="J8S10_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HAZ9630221.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            6034..7806
                     /gene="recQ"
                     /locus_tag="J8S10_001636"
     CDS             6034..7806
                     /gene="recQ"
                     /locus_tag="J8S10_001636"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HAZ9630222.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            7920..8222
                     /locus_tag="J8S10_001637"
     CDS             7920..8222
                     /locus_tag="J8S10_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HAZ9630223.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            8225..9388
                     /locus_tag="J8S10_001638"
     CDS             8225..9388
                     /locus_tag="J8S10_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HAZ9630224.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            9414..12842
                     /locus_tag="J8S10_001639"
     CDS             9414..12842
                     /locus_tag="J8S10_001639"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HAZ9630225.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            12863..13987
                     /locus_tag="J8S10_001640"
     CDS             12863..13987
                     /locus_tag="J8S10_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630226.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            13977..14414
                     /locus_tag="J8S10_001641"
     CDS             13977..14414
                     /locus_tag="J8S10_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HAZ9630227.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            14398..14736
                     /locus_tag="J8S10_001642"
     CDS             14398..14736
                     /locus_tag="J8S10_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HAZ9630228.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            14855..15415
                     /gene="rsmD"
                     /locus_tag="J8S10_001643"
     CDS             14855..15415
                     /gene="rsmD"
                     /locus_tag="J8S10_001643"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HAZ9630229.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            15412..15903
                     /gene="coaD"
                     /locus_tag="J8S10_001644"
     CDS             15412..15903
                     /gene="coaD"
                     /locus_tag="J8S10_001644"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HAZ9630230.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            15893..16936
                     /locus_tag="J8S10_001645"
     CDS             15893..16936
                     /locus_tag="J8S10_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HAZ9630231.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            17095..17823
                     /locus_tag="J8S10_001646"
     CDS             17095..17823
                     /locus_tag="J8S10_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComEA"
                     /protein_id="HAZ9630232.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            17939..18184
                     /locus_tag="J8S10_001647"
     CDS             17939..18184
                     /locus_tag="J8S10_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAZ9630233.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            18181..18399
                     /locus_tag="J8S10_001648"
     CDS             18181..18399
                     /locus_tag="J8S10_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HAZ9630234.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            18535..19074
                     /locus_tag="J8S10_001649"
     CDS             18535..19074
                     /locus_tag="J8S10_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HAZ9630235.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            19067..21340
                     /locus_tag="J8S10_001650"
     CDS             19067..21340
                     /locus_tag="J8S10_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HAZ9630236.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            21378..22424
                     /gene="holA"
                     /locus_tag="J8S10_001651"
     CDS             21378..22424
                     /gene="holA"
                     /locus_tag="J8S10_001651"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HAZ9630237.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(22513..22767)
                     /locus_tag="J8S10_001652"
     CDS             complement(22513..22767)
                     /locus_tag="J8S10_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HAZ9630238.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(23167..23436)
                     /locus_tag="J8S10_001653"
     CDS             complement(23167..23436)
                     /locus_tag="J8S10_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630239.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(23906..24361)
                     /locus_tag="J8S10_001654"
     CDS             complement(23906..24361)
                     /locus_tag="J8S10_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HAZ9630240.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(24499..26427)
                     /locus_tag="J8S10_001655"
     CDS             complement(24499..26427)
                     /locus_tag="J8S10_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HAZ9630241.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
BASE COUNT         8829 a         4606 c         5609 g         7493 t
ORIGIN      
        1 ccgtcacctg tcacagggac agttaaaaac gtgattgttc cagaaggcac tgtagcaaat
       61 gttggggatg tattagtaga aatcgatgct cctggacaca atagtgcacc gtcaactagt
      121 gcgccatcag ctgaagcacc aaaagaaaaa gtggaaacat caggttcagc aagtgtcgtt
      181 gaagctgccg atccaaataa acgtgtattg gctatgccat ctgttcgtca atttgcccgt
      241 gaaaaagatg tagatatctc acaagtaact gcaactggaa aaggtggcag agtaacaaaa
      301 gaggacatcg aaaacttctt ggcaggtggt ccaagcagtg caccagcgaa atcagaagcg
      361 ccagaagcgg cagcaccgaa agaagcagct cctgcagcag aaagcaaacc agctgcacca
      421 gcaaaaccat tcaagtccaa cttaggagac ttggaagaac gtgtagcaat gacgccaaca
      481 cgtaaagcta tcgctaaagc aatggtcaac agtaagcata cagctccaca cgtgacattg
      541 catgatgaag tagaagtgtc taaactatgg gataatcgga aacgatttaa agaagttgct
      601 gctgcaaatg gtacgaaact tactttcttg ccatatgtcg tgaaagcttt aacagcgact
      661 gttaagaaat acccagtatt gaatgcatct atcgacgatg caaaccaaga aatcgtttat
      721 aaacattact acaatatcgg tattgcaact gatacggatc acggactata tgtaccaaat
      781 gtgaaagatg cagaccgcaa aggaatgttt gctattgcag acgaaatcaa tgagaaagca
      841 aaattagctc atgacggcaa actatctgca gaagatatgc gcaatggaac aattacgatc
      901 agcaatatcg gatctgtagg tggcggttgg tttacaccag tcatcaacta tccagaagta
      961 gctattttag gtgtaggaac gattgcacaa caaccaatcg taaatgctga aggcgaaatc
     1021 gttgtcggtc gtgtgatgaa actgtcatta agtttcgatc accgtatcgt agatggagca
     1081 actgcgcaac aagcaatgaa taatatcaaa cgtcttttag ctgatccaga gctattaatg
     1141 atggaaggat gataaacaaa tggtagttgg agattttgct gtagaattag atacagttgt
     1201 aattggtgcg ggacctggtg gctatgtagc tgccatccgc gctgctgaaa tgggacaaaa
     1261 agtagcaatc attgaaagag agtatattgg cggtgtttgt ttgaatgtcg gctgtattcc
     1321 ttcaaaagca ctgatagctg caggacacca ttatcaagag tcactagatt ctgaaatgtt
     1381 tggagtaact agtgaaaacg tcaaactaga ttttgcaaaa acacaagaat ggaaagaaaa
     1441 caaagttgtc catacgttga cttctggtgt tggtttccta ttaaaaaaac ataaggttga
     1501 aacaatcgaa ggagaagcgt tcttcgtaga tgatcacaca ctacgcgtca ttcatccaga
     1561 ttcagctcaa acttattcgt tcaataacgc aatcatcgca acaggttccc gtccaatcga
     1621 gattccagga tttaaattcg gaggacgtgt gttagattct actggcggat tagcattgaa
     1681 agaagtacct aagaaatttg tgatcatcgg tggcggtgtg attggtgccg aattgggcgg
     1741 agcgtacgca aacttaggag cagaagtaac gattcttgaa ggctcaccac aaattttacc
     1801 aacttacgaa aaagatctag taaaattagt agaagatgat ttcaagaaaa aaggcgtaac
     1861 agtcgtaacg aatgcaatgg cgaaagaagc agtcgataac ggtgacagcg tgacagtgaa
     1921 atatgcagtg gacgggaaag aagaatccgt tactgctgat tatgtgatgg tcactgtagg
     1981 tcgtcgtccg aatacagatg atatgggctt agaacaagcg ggtgtcgaag taggagaacg
     2041 aggattgatc acggtggata aacaaggacg tacgaacgta cctaacatct atgccatcgg
     2101 tgatatcgtt ccaggggcgg cattagcaca caaagccagt tatgaagcaa aaatcgctgc
     2161 tgaagcaatc tctggcaaaa aagtagctgt agattataaa gcaatgccgg cagtagcctt
     2221 cactgatcct gaattggctt ctgtaggtat gacgatcaaa gaagcaaaag atgctggtat
     2281 cgaagcaaaa gcatataaat tcccattttc agggaacggt cgggcattat cgcttggtaa
     2341 aacagaagga ttcatccgtc tagttacgac gatcgaagat aacgtgctta ttggcgcgca
     2401 aatcggtgga gtcggcgcaa gtgatatggt ctctgaatta gctttagcaa tcgaatcagg
     2461 aatgaatgct gaagatatcg ccttgacgat tcatcctcat ccatctcttg gcgaaatcgt
     2521 catggatgct tcggaattag cattaggttt accaatccat atttgatttg aataatacag
     2581 gcgaaacgca actgaaaaat cagttgcgtt ttgtttttta gaattatcaa taatattatt
     2641 atgtaaactt aaaaatatga caacttcttg gtttattacc acttcctatg ctacactgaa
     2701 gaggaatatg aaataggaga gttgaagatg caagaatatc agtatccact tgatttagat
     2761 tggacaacag acgaaatggt cattgtaatg aagatgtggg aagatctgga acgtgcgaat
     2821 gaaaaaggga taaacaatga agcttttttg aagacttatc agcagtttaa aactgttgtc
     2881 aaatccattg gtgaggaaaa acgattggga cgggaatttg aaaaagcttc cggttattct
     2941 ttatatcgta cagtgcagca agcaaaaaaa aatccaaaca aaactttgag aatgaacggg
     3001 tgagataaat ggaacagatg attgatcata tcaagtcctg gcttgaagaa gctggtgaga
     3061 aaatcaaatc ttctcaacaa acattaacaa tctcgcaaaa atcaaatcga acggatctag
     3121 taacaaatgt cgatcgaaac atccagaatt ttctaatcga aaaaatccat tcctttgatc
     3181 cagaggcgaa aatattggca gaagaagaag ggtgtaatca attatcggat ctcgatggaa
     3241 gagtctttat catcgatcct attgatggca ccttgaattt tgtgattgaa ggggaaaatt
     3301 tttgtattat gctcgctgtt tatgaatccg gcgttggaaa gcttggtttc atttatgacg
     3361 tgatgagaaa tgaacttttt tggggtggaa aaggaatagg cgtgtataaa aatgatgagc
     3421 cattgcctag accagcaaat aaatccttat cggaaggctt acttggtgtg aatagttatc
     3481 ttttcggtca taataaatat ggaatccgag aaattgcgga aagcagcatg gggacacgta
     3541 tgtacggatg cgctggtctt gaactagtgg caatcttgaa aggaaaccac attgcttata
     3601 tttcaaacct tagcccttgg gattatgcag cgggaaatgt cttattggaa gagtttggta
     3661 tggtaacaag cggtcttttt ggtactcctt tgacatttga aaaaagggaa tactatttag
     3721 cagggacttc ttgtgcatat gcagaaatcg cagacctttt gaaaaaagaa ggctgaaaaa
     3781 aaggtagaaa tcattcacaa aaatgataaa aacgagcaaa agattaattt tctcgaaaaa
     3841 atgaaaacat tttactatat ttcatgaaaa aagtctgcta taattagcag tcgagtaaaa
     3901 tttgccctgt cataaagaac caataaaaaa ggagttagtt acattgaatt atagaaacga
     3961 tatccgtaac gtcgcaatta ttgcccacgt tgaccacgga aaaacaacat tagttgatga
     4021 actattaaaa caatcagata cattagacgc acatacgcaa ttgcaagaac gtgcgatgga
     4081 ctcaaatgcg ctagaaaaag aacgtggtat cacgatttta gccaaaaaca cagctgtaga
     4141 ctataaaggt attcgcgtaa acatcatgga tactccagga cacgcggact tcggtggcga
     4201 agtagaacgg atcatgaaaa tggttgacgg cgttgtgttg gtcgtagatg cgtatgaagg
     4261 aacaatgcct caaacacgtt ttgtattgaa aaaagcactg gaacaacata tcacaccaat
     4321 cgttgtcgta aacaagattg acaaaccttc tgctcgtcct gagcatgtcg tagatgaagt
     4381 tcttgaacta ttcatcgaat taggagcaga tgatgatcag ttagactttc ctgtgattta
     4441 tgcatctgca ctaaatggta cgtcaagctt gtcagatgat ccagcagatc aagaaccaac
     4501 catggcacct atttttgata caattattga aaaaatccct gctcctgtcg ataacagcga
     4561 cgaaccatta caattccaag tttcattact tgactacaac gattatgtag gtcgtatcgg
     4621 aatcggacgt gtatttagag gaacaatcaa agtaggagac caagtagcat taattaaatt
     4681 agacggaaca gttaagaaat tccgtgtaac gaaattattt ggtttctttg gactaaaacg
     4741 tctagagatt caagaagcaa aagctggaga cttgattgct gtctcaggta tggaagatat
     4801 ctttgtcggt gaaacagtta ctcctgtgga tcatcaagat gcgttaccta tccttcacat
     4861 tgacgaacca acattgcaaa tgactttctt agttaataat tcaccatttg ccggtcgaga
     4921 aggtaaattc gtaaccgctc gtaagattga agaacgtttg atggcagaac ttcaaacaga
     4981 tgtatcctta cgagttgaac caacaaactc tccagatgca tggacagttt ctggtcgtgg
     5041 agaattgcat ttgtctatct tgattgaaaa catgcgccgt gagggatacg aattgcaagt
     5101 atctcgtcca gaagttattg aaaaagaaat cgacggtgta aaatgcgaac cgtttgaacg
     5161 cgtgcaaatc gatacaccag aagaatatat gggtagtgtt atcgagtcct tgagcttacg
     5221 taaaggtgaa atgcaagata tggtccatac aggaaacgga caaatccgtt tgacattctt
     5281 aacacctgcc cgcggtttga ttggttattc aactgaattc ctttcaatga cacgtggtta
     5341 cggaatcatg aaccatactt ttgaccaata tctgccaatg cttcctggtc aaattggcgg
     5401 acgtcaccaa ggggcgcttg tttcgatcga tacaggaaaa gcaacgactt attctatcat
     5461 gagtatcgaa gaacgcggta cagtcttcgt agaaccaggt acagaagtat atgaaggaat
     5521 gattatcggg gaaaacagcc gtgataatga tttgactgtc aacatcacga aagcaaaaca
     5581 aatgacaaac gtacggtctg ctactaaaga ccaaacatct gtcatcaaaa aaccaaaaca
     5641 attgacgttg gaagaatctt tggaattctt gaatgatgat gaatattgcg aagtaacacc
     5701 agaaagcatt cgcttgagaa aacaaatttt agagaaaaat gctcgtgaaa aagcatctaa
     5761 aaagaaaaaa taatctgtaa aaggatgaag agagaaacca gcttgttata aaaaatagct
     5821 ggtttctttt tttgtccaac tcttttctgt ggagaagtca tctttgtcaa tggacataaa
     5881 ttcagaaaat acgccgaaag acgtttaaaa gacttttaaa aaacttattt ctagagagtt
     5941 tttgtttcat aataagataa tgtttcacga aaggagatca acttgtcctt cgaagaaaat
     6001 cgaagtaaaa tggcaagaga aaggagcggg aagatgaacg acttattaaa acaatacttt
     6061 ggctatgatg agtttagacc tggtcaaaaa gaaattatcc agaaagtcat tgatcaggaa
     6121 aatgtattag gaatcatgcc taccggaagt gggaaatcaa tctgttacca gcttccagct
     6181 ttactattag atgggcttac tgtggttgtg tcccctttaa tctctttgat gaaggatcag
     6241 gtggacgcgg cgaatcaatt aggtataccc gccactttta tcaatagctc gttagatggt
     6301 tacgaaacag ctagacgctt ccaagaaatc gatagacagc agtaccgttt actttatatc
     6361 gctcctgaac gttttatcat gccggatttt atccaagcaa tgaagcgatg gaacgtccgt
     6421 atgatcgcta ttgacgaggc acattgtatc tctcagtggg ggcatgattt ccgcccaagt
     6481 tatttacaga tggcgaacca gctagatcaa ctgccaaatc gtcctgtaat tgttgctttg
     6541 acagctacag cgactgtgca agtagctgct gacataaaaa gacttttaaa aattccagaa
     6601 aacaaccata ttcagactgg ttttgaacga gaaaatctac gatttcaagt aattaaagat
     6661 caaaaaaaag aacaatatct aatcgaatat ttaaagatca acaaaaatca atctggtatc
     6721 atttatgcag caacgagaaa agaagtagac cgtctctatc atttgcttaa aaaattcgat
     6781 ttttccgtgg gtagatatca tggtggtcta aatgagaatg agcgaacaga aatgcaagaa
     6841 gcctttttat acgatcgctt gcagctgatt gtagcgacaa atgcatttgg tatgggtata
     6901 aataaaagca atgtccgttt tgttatccat tatcaaattc ctggctctct agaagcatac
     6961 tatcaggaag ctggtcgggc gggaagagat ggtctttcca gtgaagccat cctgcttttc
     7021 tctcctcaag atatccaagt ccaaaagttt tttatccagc agtcccaaag agaagaaggg
     7081 caaaagcaaa aagaatatga aaaattaaaa gcgatgacag aatacgtgta tattgagtcc
     7141 tgtcttcagc aatacatcct aaactatttt ggcgagacaa gcagtccgtg caaccgttgt
     7201 ggtaactgtt tagatgacag agaaatagta gaagtaacga cagaagcaca gatggttctt
     7261 tcttgcttaa aacgtatggg tgagaactat ggtaaacaaa tgctgatgaa agtcttagca
     7321 ggatcgaaag aacaaaagct gcaagcttta ggttttggac atttatctac ctatggactg
     7381 atgaaaaacc aatcgcaaaa agaaacgatg cagttaattg aatatttgat atcgaatggc
     7441 tatcttctga ccatcaatgg tgagtatcct gttttgaaag taacagaaag agggatacaa
     7501 gtattgaaag gacaagaatc tgtttatcga aaggaaccca agaaagtcca gcagctatcg
     7561 gatgaagaaa ccgatacact atttgaagtg ctgcgggaac tgcgaacgga tctagcatca
     7621 gaagcaggcg ttcccccgta tgtcgtattt tcagattcca cattgaaaga aatgagccga
     7681 atacgtccat caagcagatt ggagatgctt cagataaaag gagttggcca aagcaagctt
     7741 gataaatatg gcgaagcctt tttatctcgg ataaaaaatg cggactctaa cgttctggat
     7801 aagtagaaag aacgaatacg taaaaatgaa taaaaacaac tggttaaatc tgtttttttt
     7861 gctccttatg aaaatcaaat atgttataat taaggaatta gaatgggagg taagcacaga
     7921 tggattcttt gtcgaaaaaa cttgcgatcc aagtattaaa tgatgaagca gaacggatca
     7981 aacgattaat ccgaaatcaa aacaacagtc tctgtatctc acaatgcaaa gccttcgaag
     8041 aagtggtaga tacacagatg tacggctttt cccggcaagt cggttttgct gtccgtatag
     8101 gagtaatcgg aaagaacgag ggccagctga tgttaagtga gctagaacga gaattgaatc
     8161 agttatatag tgaggtttac caagaaattt atgataaaaa agaagttggc aaggaggaat
     8221 agacttgcct aagaaagtga aaaaaaggca tctattagac tatagcatct tgattcccta
     8281 tttaatttta tgtgtattgg gattgatcat ggtatatagt tctacgtcgt atctattatt
     8341 agaaaacgga caaaatccgt ccgcatcagt cattaaccag agtatttttt gggtgcttag
     8401 cttgattgct atcgcactac tttataaaat gaaaacagat gttttgaaaa accagcgttt
     8461 gatcatggca gccatcgcag ttttgacgat tttgctgctg attgttgtgt tttttggtaa
     8521 ggagatcaat ggggcgaaag gttggctgca aattgcagga ttctcgatcc aacctgccga
     8581 atacctaaaa atcatttcta tctggtacct gtctctgact ttatctaaaa gacaaaacag
     8641 tgtacaaaaa gattttcttg ggactgtgaa acgtccactt gcaatggtta tcggacttac
     8701 tgcattagtc gctattcttc ccgattttgg taatgcggca gttatctttt tgattatttt
     8761 ggttctgctt ttagccagcg gagtcaatta tgtgtatact ttgattgtag gagtaggagg
     8821 cttttgtcta agtactttta cgatctggct gatcaatatc acaaacggaa agatcttacc
     8881 cggacgttta cagtatatct ataatcgatt tgctatttac caaaatcctt tctcagacga
     8941 attaaataaa gggcatcaac tagtcaacgg ctactatgcc atgttcaacg gaggactatt
     9001 tggcagggga ttaggtaaca gtatccagaa aaaaggattt ttacaagaag cacaaaccga
     9061 ttttatttat gcaatcgtag tggaagaact gggagtgatt atggggattt tgatattagc
     9121 gttgctattc tttatgattg tgcgcattgt ccttgtaggt atccgttcaa aagatccgtt
     9181 caattcgctt ttgtgcattg ggatcggcgc aatgtttttg atccaagtat ttgtcaatct
     9241 tggaggaatt actggcgtta ttcctttgac agggatcacg ttcccatttt taagtcaagg
     9301 aggctccagt ttgctgatgc tttcgatttg tgtcggcttt gtcctcaaca tcagtgcgga
     9361 tgaaaaacgc aagagcttag gtttataata aaaaaagatg taggagtggt tcgatgaaaa
     9421 aagttttagt tgctaacagg ggtgaaatcg ctgtacgtgt atttcgtgct tgtacagaat
     9481 taggaattaa aactgttgga atctatgcag aagaagatga atattccgta caccgtttca
     9541 aagcggatga agcatattta gtaggacaag gaaaaaaacc gattgatgcg tatctagata
     9601 ttgaagggat catttctatc gcgaaagaat gcggagctga cgctattcat ccgggttacg
     9661 gtcttttgtc ggaaaacttg aattttgcgc aacggtgcga agaagaaggc atcatttttg
     9721 ttggacccaa actgcatcat ttagatattt ttggagataa aatcaaagca aaagctgcag
     9781 ctatcgaagc ggggattgct tcgattccag gcacagatgg accaatcgct tctatagacg
     9841 atgccttgga gtttgcgaaa caatacggtt atccgattat gatcaaggca gctctaggcg
     9901 gcggcggacg cggcatgcgt gtagctcacg atgaaaagag tgcaagagag ggctacgaac
     9961 gtgcgaaaag cgaagcaaaa gcagcctttg gtagtgatga agtgtatgtt gaaaaataca
    10021 tcgctaatcc taagcatatc gaagtacaga ttctcgggga tacgcatgga aacgtcatcc
    10081 atctttttga aagagattgt tctgttcagc gccgtcacca aaaagtagta gaagtagcgc
    10141 cttgtgtctc tatgaatgaa cagcaacgtc aaaaaatctg ccaggcagct gtccaattga
    10201 tgaaatatgt cgggtatgtc aacgcaggta cagtagaatt tcttgttgaa ggagatgatt
    10261 tttactttat cgaagtcaac cctcgcgtcc aagtggaaca tacgatcaca gaaatgatta
    10321 cagatattga tatcgtaaca acgcaactgt tgattgctca aggtttggat ctgcataaag
    10381 aaatcggatt gcctcagcaa gaaggaatta aattaaatgg ttcagccatt caatgccgaa
    10441 tcactacaga agacccgttg aataactttt taccagacac agggaaaatc gatacgtatc
    10501 gttcacctgg tggttttggc gtacgtctgg atgtcggaaa tgcttacgcg ggctatgtag
    10561 tgacaccgta ttttgattca ttgctagtaa aagtatgtac gcatggtgct acctttgaaa
    10621 cagccattca gaaaatggaa cgttgcttga aagaatttag aatccgtgga gtgaaaacaa
    10681 acattccatt tatgctcaat gtcatcacac atcctgaatt ccaatcagga aatgcaaaaa
    10741 caaccttcat tgatagtaca gcaacattat ttgaatttcc tcgactacga gaccgcggaa
    10801 acaaaacgat gaaatatatc ggtgaaatta ctgtgaatgg ttttccaggt atcgaaagtg
    10861 gcgaaaaacc attttatgaa gaaccacgta tgcctaaaga tctaatcaca agaactgatt
    10921 acgtaacggc taagaatgta ttagatgcga agggtgccga tgctttggtc gaatggatca
    10981 aaggacagga aaatttgttg ttgacggata cgacatttag agacgcccat caaagtctgc
    11041 tagcaactcg tgttcggaca aaggatttca agcagattgc acgtttgact ggagaaggtc
    11101 ttcctgaact cttttcaagt gagatgtggg ggggagcaac atttgatgtg gcttaccgct
    11161 ttttgaatga agatccttgg caacggttga gaaaaattcg ttctttaatg cctaatacgt
    11221 tgctgcaaat gcttttcaga ggttcaaatg ccgttgggta ttctaattat cctgacaatg
    11281 tattggtgga atttgtcaaa gaagcagcag cgcaaggaat cgatgtattt cgaatctttg
    11341 atagtttgaa ctggactcca caaatggaaa aaagtatcca agctgtacgg gatactggta
    11401 aaatcgcaga ggcagctatt tgctatactg gcgatatcaa cgatccaagt cgggcaaaat
    11461 acaatgttca gtattataaa gacatggcaa aggaactaga acaactgggt gcgcatatca
    11521 ttgcaatcaa agatatggct gggctgctta aaccgcaggc agcttatcgt ttgattagtg
    11581 aattgaaaga aacgacagat ctgccaatcc atctgcatac tcatgatacc agcgggaatg
    11641 gaatcatcac ttattctgct gcttcaaaag caggagtaga catcgttgac gtggcaatga
    11701 gtgcaatgag tgggaatact agtcagccta gcatgagcag cttgtattat gcactggtca
    11761 atggtccacg gctgccagaa atcacgattg aaaatgcaca gaaattaaac cattattggg
    11821 aagatgtgcg catgtattac aaaccgtttg aaaacggctt gaatgctcct gaaacagaag
    11881 tatatatgca tgaaatgcca ggaggacagt attcgaatct acagcaacag gcaaaagctg
    11941 tcggattagg tcatcgctgg gatgaaatca aacaaatgta tcatactgtc aacttgatgt
    12001 ttggcgatat cgttaaagta actccatcat ctaaagtagt tggagatatg gcactattta
    12061 tggtccaaaa tgatcttaca gaagaagata tttatgaaaa aggcgaaaca ctaagtttcc
    12121 ctgaatctgt tgtgactttc ttccaaggag aactagggca acccgttggc ggatttccta
    12181 aaaaattgca aaagattatt cttaaaggca gacctgcatt gaatgaacgt ccaggtcttt
    12241 tggctgaatc agtcgacttc aacgaagtaa aaaaagaatt ggcagaaaaa attggctatg
    12301 aaccaaaaca agacgaagta ttaagctatt tgatgtatcc gcaagtcttt ttggactatc
    12361 aaaaagcata taatcaattt ggcgatgtta cattactgga cacaccaaca tttttccaag
    12421 gtatacgttt gggtgaaaca atcaatgtac aaatcgaacg cggaaaaacg cttatcattc
    12481 gtttagatga aatcggagaa cccgatatcg aagggaatcg cgtactgttc ttcaatttga
    12541 atggacaaag acgtgaaatc actatcaaag ataattcgat catcagtacg gtccaaaccc
    12601 gattgaaagc tgaaccgaca aaccgagaac aaattggagc aacgatgtct ggttctgttt
    12661 tggatgtatt agtgaaaaaa ggcgataacg ttaaaaaagg tgatacgttg atgattactg
    12721 aagcgatgaa aatggaaacg gccatcgaag cacgttttga cggagaagtc gcacatgtat
    12781 atgtgtcttc aggagacact atttcgtctg gtgacctttt gattgaagtg actgagaaat
    12841 aataagcgaa aggtggggaa acatgaaaag actgggtttg ttttggctga ttctgctatt
    12901 agttattgtg gcattctaca tggaaccagt cttgtttccg ccaaaacttg aagtgaagga
    12961 aaactctgat caacaaatat caaaccaaat gacaacgtgg aaataccagg agcttaaagc
    13021 aactggtttt tctacttata tcggaaaacc gatcgatcag ctggaaaagg attttggcca
    13081 agcctatgat cgattaacta gcggatttgg ttttgaaaca agatattatg aaaataaagc
    13141 tagtcatctc acatttgaag cgaacatcca agacagcaga gtcacaactg ttaaagtact
    13201 gcaaacaggg cctgctgata tcgcgccgtt ttatttaggg atgacgatgc aagatcttac
    13261 gaaaatcact actatctata ctaatttcac ttttgagtac catgatacag aagttggaat
    13321 cgaactaatg gaagaggata tgaattatcg tccgctaatt gcttttgata acgacacttt
    13381 tgctatttta ttttttgatc aaacaacaaa cggcctattt tcagttgtgt atttagataa
    13441 agatagtctt ttgaaactat tgccatatca agtgtttggt gaaggccttc cacattatca
    13501 agcagataaa tcggctgatt gggaatcaat caatcgcgtt aaagaacgaa aaagtacgac
    13561 tttattaaat atgcttagaa gagaagacga acttcccata tacaatcaaa cacttgcctt
    13621 tcaaaaccac agtcagctgc tactacatga ttttttgaca aggcctgagg aaatattgtc
    13681 agaggaacgt atggctgatt ggcaaaaatc gctaggcagt gctcaaacga cagtgaaatt
    13741 ctcactgacg aatgatgaat tggagaagtt aatcagtaaa caaaaattag aaaatactag
    13801 tgggctattt attcatccgg cgattgacgc tactttttcg tttttatatt ggtacagcga
    13861 tccttacaac catgaccgtt tcatggaccc gggaacggat tctgtaggca ttgctttttc
    13921 taaagaaaat atgttagtct tattgcaaga agaaaacgga gaaagtagtg atagcagtga
    13981 tcgttaacga agagctgttt caactggagg atcaatgcct ccaagtcgct gaaatgataa
    14041 aaaagagtaa aacgatggct tcttatcttg aacataaaca gtcaatggaa gaatctgcaa
    14101 aagtttgcca gttgaaagaa gcgttcttgt ctaagaaaga agcatttgaa aatgtagcgg
    14161 catatggtga gtatgcacct gattatcgtg aaaaaaaacg agctgttcga aaagcaaaaa
    14221 gacagcttga tatggatgag catgttgcag ctttccgata tagtgaaaca cagctgcaaa
    14281 gtctgttgga tcaaattgtc caagtacttg ccgaagaagt ttctaatgaa atcaaagtag
    14341 atgcaggtag cccgtttttt gaaacgaaaa aacactttgg atgcggaggt aattgtcatg
    14401 caattagaca atagtgaatt tgaaataaca aaacgacgcg ggctgatcgt atgggtctac
    14461 agcttaaaac aattaaagaa tctgaaaaag ttcggcttgt tgcattatgt ctcaagaaga
    14521 atgaaatatg tcgtgcttta cttaaatgaa gagacattgg aagaaacaga agaacgaatc
    14581 cgtaaattac attttgttcg aaacgtagaa cgttcttacc gaccggatat cgaaatgaat
    14641 tttgccgaaa aaataggaaa caaaacagta ttaaaagacg aaggtttcga aattgaagag
    14701 ctaaatacag aaatccgatt agctgaacat ctttaaaaat ctcttatgag cagtttttaa
    14761 ataaaaaata acttggataa cgatcgattt ttgatcattg tccaagtatt tttttggtat
    14821 actagtacca gtaccatttc taaggagtga gtagatgcgg ataatatcag gaaattatgg
    14881 cgggcgccgt ttaaaaagtt tagcaggggc gaacaccaga ccaactacag ataaagtaaa
    14941 agaatccata ttcaatatga ttggaccata ttttgatgga gagacagtat tggatctgtt
    15001 tgcaggaagc ggtggtttag ctatcgaagc agtatctaga ggctgcagtc atgcggtatg
    15061 cgtagacaaa aattaccaag cgctaaaaat catcaaagaa aacatcgaaa ttacgaaaga
    15121 accagagaaa tttaccacaa taaaacttga tgcggacaaa gcaatcgaac ggctagcagc
    15181 ggagaaacaa caattcgact acttgtttct tgatccgcca tatgcaaaac aaaaaataat
    15241 cgatcaaatc cataaaatgg aagaactggg acttttttct aaaaccgcag ttatcgtatg
    15301 cgaaacggat aaaacagtcg aattgccaga aactgtggct ggattccatc aaataagaaa
    15361 acagatttat ggcataacgg ccgtaactat ctatagaaaa gagggaaatc aatgaaacgt
    15421 gcattattcc caggaagttt tgatcctttt acaaaaggtc acttagatac ggtggaacgt
    15481 gcggctaaat tattcgatga ggtagtaatt ggtgttttta tcaatacttc aaagaaaagt
    15541 ttgtttcccc cagaagaaag aatgacattg atcacaaaag ctgtttctca tcttcctaat
    15601 gtaaaagtca tgcatcaaga aaatcaattg acggtagaaa cagcaaaaga gattggtgca
    15661 gatgcgttga tcagaggcat acgaagtatc aaagactttg aatatgaacg agagattgct
    15721 cagatgaatc atcatctata tgatgaattg gaaactgtct tcttattagc aaaaccagaa
    15781 tatagtcacg tgagttccag tattttaaaa gaagtactgc actttggcgg agatgtgagc
    15841 agctacttac cgccagtgat caacgaagct ttagctggaa agcgtgaatc aaatgaaagc
    15901 taaacaatgg ttgaaaacag tactgattat catatttgga atgttgatca ttggatttgt
    15961 agtagttccc ttgccgtatt atgtagaatc accgggagcc acgatcgatc tgaaagaact
    16021 aattacggtc aatgataagg aagataaagg ttctgggtct ttctctctta cctctgttgg
    16081 tatcaggcaa gctacaggtt tcttagcttt aaaagctaaa atgacccctt ttgaagaatt
    16141 gatcagtgaa gaagaattga ctggtggggc gacaaatgaa gaatataatc aaatgcaaca
    16201 gtattatatg gattcttccc aaaatgcagc aatcgaacaa gcgttaaaac ttgcagacaa
    16261 gccttataaa atggaattca aaggcgtata tgtcatgagt gtagagaaaa catcgaattt
    16321 ctttggcaag ctttcagttg gagatacagt aacaaaagta gacgggaaaa gctttcaaag
    16381 tacagaagca tttatggatt atgtaaaaag ccaaaaagtt ggacaaacaa tcgaaatcag
    16441 ttatttgcat aatggtgaag aaaaaacagc ttctggtgat ctgatcgagt taccaacaga
    16501 taaaaaggca ggaataggta tcacgcttac tgaccatacc gagatcgaat cagatacaga
    16561 tgttcgtatt aattctggct ctatcggtgg gccatcagcg ggattgatgt tcactttaga
    16621 aatctatgaa caagtcactg gtaaaaactt gcgacatggt aagcaaattg caggaactgg
    16681 aacgatcaac agtgaaggag aagttggccg aatcggagga atcgataaaa aagtggcaag
    16741 tgcggataaa gctggcgtag agattttctt tgcaccagat gatacgattt cagacgatgt
    16801 taagaaagaa tatcctgaaa taaaaaccaa ctacgaagaa gcaaaagctg ccgctaaaaa
    16861 attgaattcc tcaatgaaaa tcgtaccagt aaaaacagta caagaagcgc ttgactatct
    16921 agagaaaatg aaatgaaact aaataattaa agaggggttg tgacacgagt tctgtcacaa
    16981 cccctctttt tcgtcaaaaa tcttcacgat aaaaataaaa acaaaagaaa aaattgacgt
    17041 aattagatgt tgaagggacg attttgccag agctcactgt ttcttcaatt ttaaatgaaa
    17101 ggagtaatga atgattttta ctggtcattc tttgaaaaaa gaacaatgat agaaaaaatc
    17161 agcaagaaaa tactagcttc acccaaattg atcatttgga tgtctatgat agttcttatc
    17221 ttttgtatcg caagtggttt tttattatca aatttgctat tttatagaga aacagaagag
    17281 actgctgcaa aagaaatact ttcttcgttt agttccagtg gagaagatcc atcagctgaa
    17341 ggaaacgatg tagaagagga tgctcgtcca aaggtcatgt acaccgatat caaaggaagt
    17401 gtgaaggagc ctggtatcta ttccttttct tcagaagaac gggtctatga tgtactaaag
    17461 cgtgcaggtg gattattaga agaagcggat agcgatcgaa tcaacttttc tgcgaagata
    17521 gaagatcagc aagtcctata tatccctgct gtaggtgaag agctgccaga acatcttgat
    17581 cagttggcat cctcggaagg aaaacagcct acagcagatt ccgagcctcc caaaataaat
    17641 atcaatacag ccactccatc agaacttcag cagattcctg ggatcggatc agtcaaagcg
    17701 caagaaatca ttcgatttag agaagaaaac ggatccttcc agaaagtgga agacctgcag
    17761 gagatttctg gtatcggtga aaagacagtt gaaaaactaa aaaacttcgt tacaattaaa
    17821 tagaatgatt caaaatcgac tggcacgagc aataaatgga cgctaatgga tactaagaat
    17881 aatccaattc taagagcttg gcaggacgag gaggtagtat ttttggatag gaaatagctt
    17941 gattgttcgc aaagaaacat taaaaaaacc aatgctgaat gtctatctcc aaaataaaat
    18001 atctgggatt catattatga atacggctgt cagcggcaat aacagtcaag ctctacgaga
    18061 acgctttgcc aaagatgtac ttagctatac agcagataaa gtatttattc tcattgggac
    18121 gaatgatcta gcagagcata aacaactttc taaagaaacg taccaaaaaa tctgcagtgg
    18181 atgatagttc agctgaaaaa agactatagt tctgatcatg ctttctttat cacgccacca
    18241 gcagtcgatg agacaaaaca aaaatatcgg aataacaagt tgatcaaaga atatatctct
    18301 gttctcacag aagtagcaaa acgccatgat tgtgaagtat cgatttttat acggaatttc
    18361 ttgaacaaat ggattcgaag aatttttata atgggctaat ggatgacgga cttcatttcg
    18421 gcagtgaagg gtaggatctt ttgtcagaca ggatgattcg ttatatttaa agaatatttt
    18481 gtttaagcaa tgagtacttt ttaatcaact tgaaaaaacg gaggaatata aaacatgtta
    18541 gaaaaatctt caaaagcatg cgatacgaat aaagaaaaag ttactgataa gtcacataat
    18601 gaacgcattc cttgggacca gtactttatg gctcaggcag tactgttatc tttacgtagt
    18661 acgtgtacac gtttagaagt aggagcgaca ctcgttcgag aaaaaaggat cattgctggc
    18721 ggctataatg gagcagtcag tggagatgtc cactgcatag atgaagggtg ttacgtcgtg
    18781 gatggacact gcttgcgaac gatccatgca gagatgaatg cactcctaca gtgtgcaaaa
    18841 cttggtatcc cgacggaagg ttcagaaatc tatgtcacac attttccatg tttggcctgt
    18901 acaaaggctt tgttgcaagc tggtgtgaaa gggatcaatt atctccatga ctatcgaaat
    18961 gatccttatg cccaagcgtt gatcgaacaa ttaggtgtat ctgtacacca agttgcttta
    19021 gactcacagc atttttcaaa acttcaaaat gaattaacag gaaaacatgt ctagcgtttt
    19081 agaaaggcat gttcgaaatc ggttgatttt tccggcaatt acgtcgatga ttatctgttt
    19141 gttgtattac actgacaatt ggggttatcg tttgcttctt gccggaattt ttttatggtt
    19201 ttcgctaaaa gaaggacgtt ttatcgcgta cttgtgtatt ttgtgtagca taacggtatc
    19261 catttcttat aggctacaag agtattcatt tttagaggaa aaaacaacat ctgcgcaaat
    19321 tactgtattt acagatacga ttcgtgcaaa tggtaatttt ttgacaatgg aaggaaggtt
    19381 atcagagaat aaacaaaagc tccagctttc ttatcaagta aacacagaag cagaattgaa
    19441 aacatggctt aacttccgag gaaagggaat agaattgact gctgaaggcg agttcatctc
    19501 tccagcaaaa aagcggaatc tttataattt tgaccaagaa gcttacttca ggaaccatag
    19561 aatttctgga cggttccaaa ttcaaaagat tgaacagatc accatgcaaa atcactggcg
    19621 aaactggctt cagagaaaaa gaggatcttt tatctccttt gtccaatctg aatttccgca
    19681 aaaaacaagt gtatatatta attctttatt atggggctat aaagatgcag gattcagaga
    19741 accagaagaa atttttaggg agagtggttt gctgcatctg ttcagtctat cgggtctaca
    19801 catccaattt tatttagggt ggctgtatta tttgtttcga cgtatcggat ggccactaca
    19861 cgtcagtatt attccgttga gtctactaac tatctgttat gtttctattg caggaagttc
    19921 tatttctgtt ttgcgtgcta gtttgctgtt tttattgcga ttgctagtca aattgctgaa
    19981 taagcattat tccaccatgg acttatttgc agttgtcttt tggcttcttt tactatttga
    20041 tcctcgattt ctttttcatg cgggtggaca gcttagtttt ttcatgagtt ttttgtttat
    20101 cctgatttct tttgatggag attggttgaa aaaaacggcc tctcacgtcc tgtttactat
    20161 gatcacgatg ccgttgattg tatggcattt ttatgagtgg cctattttag gtagtctttt
    20221 tacattactg attgcaccgg tattcaagtt tctttttctt cctggtgtgt tatttctcac
    20281 actcttcaat cgctggctgc cggaaacttt acttttgctg atagaagagg gattaatctt
    20341 atttgagcga ataatcgatt tttcttcagg gtcgtctctc attataggac gtttgcccct
    20401 tgtgctatct gggatgtata ttttcggatt actgatttgt atggataggt tgaaagaaca
    20461 acctgtgaaa cacttgtttt atgttggtct tttttctttt atttttttga ctttgccatt
    20521 tttacgcttt tcttcaacga tcgcttttat cgatgtcggt caaggagaca gtatcttttt
    20581 gcaaagtcct tttcgaaaag aaacgatttt gatcgatact ggaggtcagt tacactttga
    20641 aagagaaaag tgggcgcaag gtatgatacg tcctcctgct gaaagaaata tcgttccata
    20701 tctaaaaggt caggggataa gtgtaatcga taaactcatc ttgacacacg acgatacgga
    20761 tcatgtggga gaattaccca cgttatctca gcattttact atcaaaaaaa tttatatcgg
    20821 ttggggcgct ggacgaaatg agccattaca aaggcattta tctgaagctc aaaaaaatgg
    20881 tactgagatc attgaaatca aacatgggga caggatcagc ggttattatg atctttatgt
    20941 attgactcct tttgaaaagg gagagggaag aaatgaagat tcgattggtc tatggatgga
    21001 atataacaat aggcgctttt tatttttagg agatttgaat caagcaatgg aaaaacaatt
    21061 gcttttgatt tatcctaatc tgaaagccga tgtagtcaaa ttaggtcatc acggtagccg
    21121 tacgtcaagt aacacagatt ttctttccca tattgaagca aaacatggga ttatatcctg
    21181 cggcgtaaat aatcgttatg gtcacccgca cagcgaagta ttggagacac tagaagaaaa
    21241 tcagataaaa acatggcgaa cggatcaaca aggaatgatc acctatcgct ggcatccagt
    21301 ttttcatcct catgggctag tggaaacaat gatagactag taattctcat ctgctcatgg
    21361 taggataatt tttgaaagtg gtgagtaatt tgagtataca agcagagtta caaaaaatac
    21421 gtaaagaaaa acttgcatct tgttacttga ttttaggaac agaaaagttt ctccaagatc
    21481 aagttcggac agaaattgtc aaaaaaatcc aattagaggg cgaagatgac ttaaattttt
    21541 taagttttga catggaaaat gcaagtttag atgaggtagt agctgaagca gagacgttgc
    21601 cgtttttcgg agatcaacgg ttagtattcg tagagaatcc ttatttttta acaggtgaaa
    21661 aagtaaacaa tggaatcgaa caaaatactg atttattgac ggcttatttg aaagaaccat
    21721 tagaatcgac tgtattagta ttctttgcgc catatgaaaa gttggatgaa cggaaaaaag
    21781 taacgaaaca attgaaaaaa acagcaatta tcatcaatgt ccaacagttg aatgaaaaag
    21841 aagtacgtca atatctgatg aataccttag agaattcctc aatcaaaatg gaacgaagtg
    21901 caattgattt attcttgagg ttgaccgact tagatttatc caaaatgatg agagagttac
    21961 agaaattggt cctttatgga caaaatcaac agcaaatcac ggtaagagaa gtagaagaat
    22021 tagttcctaa aacgttagaa cataatattt ttgacatgac ccaatatatt ttaaaaggga
    22081 agacggaaca agctttgcgt ttatacgaag atttagttat gcaaggggaa gaaacaatca
    22141 aaattaatgc gattttgctt tctcaattac gtttattttt acagacaaaa tttcttgtaa
    22201 agattggtta tcagcaggca aatattgctg aaacattgaa aatccatcca tatcgtgtaa
    22261 aacttgccat gcaggaagta aaaaaattcg atgaacattt gctggtacag ttgtttgatc
    22321 aattagttga gatggattat caaatcaaaa cgggacaaat cgaaaaagaa ttaagttttc
    22381 aactattcgt tttgcgcaca gggcagttgt taagaaatcg ataagaagaa agacgagggc
    22441 aaagcatgcg ggaaggtcgt ttgtttttgt cctttttttg acaaataaaa aaatcggccg
    22501 aagccgattc ttttatttag cgattttttt gcttaaacga gatttgtcgc ggttagcttt
    22561 gtttttgtgg attagacctt ttgattcagc catatcaata gctttaacag cttctttata
    22621 taacgcatct acgttgtcag cacctgaagc tacagcatct tcaaattttt tgattgcagt
    22681 acgcatagcg cttgtttgag atgaattttt cacattagcg ttttcgcttg tacgaacacg
    22741 tttgattgca gattcaatgt ttggcattag tttcacctcc gataacttaa gttcttacgc
    22801 gtgttaccgc ataattcaac attcattatt atacctaaag gcagcgtgct ttgcaatatg
    22861 aacatgacaa gtttttttcc ttaacagtct tttattagga ttttttttca gtaaaaacgg
    22921 atagtacaag ctgaaaaaaa tcaaaaagac gctattgtgg gaggcaatag cgtcaaacca
    22981 aactagattt ttatttatct atttaaacaa agtttgaatg ggaatgtttg gtactaagtt
    23041 attatataac aaagagaacc gtttgcaaag ttttttttga aaagggatac gattccctgt
    23101 tgttctttgt ttttctatta agaaactgca gttattttat aaccagtatc ctttgatcag
    23161 taaaggctat tctggtgtac cgattatttt aatgtattca tcgatatttt ttatcaacat
    23221 tttttttatg accaactggt tccgacggtt ccatttgcca cttacttcca gcacatattt
    23281 atttaggggc aaacgtaaga tatattttgc caaatagcga tctttaagca ggccattgat
    23341 cacacggtcc tcaagctgca agttgatccc agtcagcatc attggctgtt cttgtaaaac
    23401 gtacgtatca attaaaagac cttcaaaagt ttccacaagc gtcttccttt cttttcaaag
    23461 taacctgaaa acaggcacta attcttccat tttgatattc gttgaagtgg atgcgatcat
    23521 tctttctttt gtccactgta atctagtata acaaaaaaga gcagaagagc caaaaagaaa
    23581 aaagagcatc gaattctata ggaagtctca ttggcacggc ctaaattatt acaaaacatt
    23641 gattaaaaaa agcccctgca tcgcaggagc atcccctata tcgttttaat aggtcaatca
    23701 aaaagcagta tcaaacacat tttgtatcaa atcaggaaat aatagataag ctaagcccag
    23761 aatcaaaagt accgctagaa gaaaccagcc gattgttcct atgaaatact ttaatttttc
    23821 gaacattgta tcacctcgtt gtcagtatat cacggatcag taaattgggg gtgttaagaa
    23881 tctcctaaaa tagacaaaat ttgttctatt ttcctaaagc aaatacttgt aagatacagt
    23941 aagtgatacc agaagcaatg accggtccgg cggcgattcc tcttaagaag acaacaccta
    24001 aaatcgtgcc gaaaacaagt gcaacagtga tttgtggatc agaagcaatc aatcctacac
    24061 ccttggaaga taagacagcc actagcccac cgcaaaaaac agctacccag ccaatagggg
    24121 atttaaaggc ttctaataga tcacgtagac cgatttctcc tgttgcgata gggattagaa
    24181 tagccgctgt gatgatcgtc accccaatat tgattccttt gccttgaagc caagggaaaa
    24241 aggaacggga ggctggtatg agcttcataa tcaaaacaaa agctgccgct atcatcagac
    24301 tttgattttt agctaaaatt gctacaagta aaataattcc taaaaaaagc caactttcca
    24361 tgaaatatat tcctcacttt cttcgaaaca atcataacat gtttttagaa agttacaaaa
    24421 gtaggaattc atccttcaag acctattcat aagctgtttt tttcataaaa taaacaaaat
    24481 cataaaaaaa cactttgctt atttgacaga agacagccgc gctttgtata gtggacaaga
    24541 cttacatttt tttgaagaat cagaaagatc aggtaaaggt cttagtaaac gcaagccatt
    24601 cagaataacc aatattgtgc ttccttcgtg tcctacaact ccaagaggta gatttaaaaa
    24661 ttgcaggaag ttagaagcaa tcaacaagag aataacaaga atcgaaaaaa taatattttg
    24721 tttgatgatc cgccgcattt ttaaagatag ccgatgactg tagacaaatt tatttaagtc
    24781 gcttttcatt aagacgatgt ctgcgatatc catagcggca tctgtccctt gccccatagc
    24841 gacacctaaa gaagcggctg ctaaagcagg cgcatcattg actccatcac caaccatcgc
    24901 atttacttgg taaagttcat tctctttttt gactagttgt gttttttctt ccggagtaca
    24961 gcttgcatag taatgttcaa tccctacttg ttcagcaatg gcctttgctg tgccagaatg
    25021 gtcgccggtt atcatacttg tatggatgtt ttgggattta aagtaggaaa ttacttgttg
    25081 ggtatttgct tttggaatat ctagcagacc taaaacagca attaactgct gatctttaga
    25141 aagataaatc acggttttgc cttgattttc caaacgttcg atcatttccg caatctcttt
    25201 gctgattatc atcgtctcag gatcatatgc gtgcttgcca actttccatt gcgcacctaa
    25261 ataggtagtt tgtaatccaa aaccagtaat ttcttctatt ggtaagtatt ggatttcttc
    25321 aggtattgtg caatcgaaat attgcaaaat cgcatgagca agtggatgcg tcgttttttg
    25381 ttccatagca acaagaagtt gttgtgccaa atccttttca tcaaagaaaa agctgtcagt
    25441 tacaactggt tttcctttag tgagcgttcc tgttttatca aaggcaatcg cttttaattc
    25501 agaaagcttt tctaaatgga taccgccttt gattaaaatc ccattttttg cagaatttga
    25561 aagagcagct agagaagctg gtgtagcaga tgcgacaagc gcacaaggag aagccacaac
    25621 taataatacc attcctcgat aaaagctttc atcccaactc caacctagga aaaagtgggg
    25681 gagaaggatc attagaggaa cagcaagcaa aatcaatttt acataattat tttcgattcg
    25741 ttcgataaat gaagctgttt gagttggcgt attctgcgct tcttctacta attggataat
    25801 cttagcaaag acagtttcgg aactcgtttt tgttactcga atcgtgatgg gatttccttg
    25861 attcagcgtt cctgcataca tctcatcgcc taaatatttt tctacaggca cagattcacc
    25921 gcttaatgca gactcatcga tcgttgcctg tgtgctttct aaaaagccat ctatcggaac
    25981 agctgctcct ttagcgacaa ataccaagtt atccaccttt agttgagaaa catctacttc
    26041 ttgcatttgt ccattttctt ttaataattg ggctttttgt ggttgaagat tcatcaaagc
    26101 agtaatttct ttttgacttt tattagttgt gtattcctct aatgcaccgc ttaaacaaaa
    26161 gatgaatgtc aacattgctc cttcaaagta attaccgatc aaacaggcac caatagcagc
    26221 taaagccatc aataaatcca cattcagtgt ccgatcattc cacaattctt tcaagccttc
    26281 cgatgtttgt ttatatccac cgatgataat ggcactgata taaaaaagtg gggtgatggt
    26341 aagagagaat cggtcgaaga taaaaccgaa gatcataaat aaaaggcagc cgattgttgc
    26401 tgcaaaagct tttttctgat tagtcatcgt tattagacct ccttgtcaaa acaaggatag
    26461 cataataaaa atgtaattga taataataac agctaaatga gaacgataat ggttatcatt
    26521 tggtgattaa gcttgat
//
LOCUS       DADQDV010000038        26158 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.038, whole genome shotgun sequence.
ACCESSION   DADQDV010000038 DADQDV010000000
VERSION     DADQDV010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 26158)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26158)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26158
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.038"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(62..1093)
                     /gene="queA"
                     /locus_tag="J8S10_001656"
     CDS             complement(62..1093)
                     /gene="queA"
                     /locus_tag="J8S10_001656"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HAZ9630242.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            1286..2461
                     /locus_tag="J8S10_001657"
     CDS             1286..2461
                     /locus_tag="J8S10_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="HAZ9630243.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEAIKLASRIAIMSEGRVIQFD
                     TPENILRHPANDFVEELIGEDRLLQAKPNATRVGEVMLNTAITITPEKSLQEAIKLMR
                     EKRVDTLLVTDNSNVLKGFIDVETLNKKRGKVSSVGDILNKHVFYVKESAYLRDTLQR
                     ILKRGLKYVPVVDEQNKVVGILTRASLVDIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            2465..3106
                     /locus_tag="J8S10_001658"
     CDS             2465..3106
                     /locus_tag="J8S10_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9630244.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            3103..4020
                     /locus_tag="J8S10_001659"
     CDS             3103..4020
                     /locus_tag="J8S10_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HAZ9630245.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            4017..4688
                     /locus_tag="J8S10_001660"
     CDS             4017..4688
                     /locus_tag="J8S10_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9630246.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(5229..5717)
                     /locus_tag="J8S10_001661"
     CDS             complement(5229..5717)
                     /locus_tag="J8S10_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HAZ9630247.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(5918..6184)
                     /locus_tag="J8S10_001662"
     CDS             complement(5918..6184)
                     /locus_tag="J8S10_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HAZ9630248.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(6184..6447)
                     /locus_tag="J8S10_001663"
     CDS             complement(6184..6447)
                     /locus_tag="J8S10_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAZ9630249.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            complement(6440..6712)
                     /locus_tag="J8S10_001664"
     CDS             complement(6440..6712)
                     /locus_tag="J8S10_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630250.1"
                     /translation="MYWCCCIDSQALDSTFAKDDTLLPITLRLATASRKGVRSERGQR
                     SSLKRGLFLYVKKRKSLLNLSALLYFFDVLNQVRYNYIRKRRRDNG"
     gene            6923..7108
                     /locus_tag="J8S10_001665"
     CDS             6923..7108
                     /locus_tag="J8S10_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAZ9630251.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(7250..9073)
                     /locus_tag="J8S10_001666"
     CDS             complement(7250..9073)
                     /locus_tag="J8S10_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HAZ9630252.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(9671..12376)
                     /locus_tag="J8S10_001667"
     CDS             complement(9671..12376)
                     /locus_tag="J8S10_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HAZ9630253.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(12682..13629)
                     /locus_tag="J8S10_001668"
     CDS             complement(12682..13629)
                     /locus_tag="J8S10_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HAZ9630254.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            13819..14088
                     /gene="rpsN"
                     /locus_tag="J8S10_001669"
     CDS             13819..14088
                     /gene="rpsN"
                     /locus_tag="J8S10_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HAZ9630255.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(14264..14626)
                     /locus_tag="J8S10_001670"
     CDS             complement(14264..14626)
                     /locus_tag="J8S10_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAZ9630256.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(14637..15758)
                     /locus_tag="J8S10_001671"
     CDS             complement(14637..15758)
                     /locus_tag="J8S10_001671"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HAZ9630257.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(15774..16124)
                     /locus_tag="J8S10_001672"
     CDS             complement(15774..16124)
                     /locus_tag="J8S10_001672"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HAZ9630258.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(16254..17765)
                     /locus_tag="J8S10_001673"
     CDS             complement(16254..17765)
                     /locus_tag="J8S10_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAZ9630259.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(18087..19439)
                     /locus_tag="J8S10_001674"
     CDS             complement(18087..19439)
                     /locus_tag="J8S10_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HAZ9630260.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYLEKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(19592..20668)
                     /locus_tag="J8S10_001675"
     CDS             complement(19592..20668)
                     /locus_tag="J8S10_001675"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HAZ9630261.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            20864..22609
                     /locus_tag="J8S10_001676"
     CDS             20864..22609
                     /locus_tag="J8S10_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HAZ9630262.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(22889..23326)
                     /locus_tag="J8S10_001677"
     CDS             complement(22889..23326)
                     /locus_tag="J8S10_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HAZ9630263.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(23310..24683)
                     /locus_tag="J8S10_001678"
     CDS             complement(23310..24683)
                     /locus_tag="J8S10_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630264.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(25005..25493)
                     /locus_tag="J8S10_001679"
     CDS             complement(25005..25493)
                     /locus_tag="J8S10_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAZ9630265.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEAFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(25515..26117)
                     /locus_tag="J8S10_001680"
     CDS             complement(25515..26117)
                     /locus_tag="J8S10_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAZ9630266.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         7503 a         5560 c         4838 g         8257 t
ORIGIN      
        1 ctttgtcata aaatctttgt aaagcttttt tgttattcaa aactagcggc ttttcataac
       61 cttatttcac gaacatcgca tctccaaaac taaagaaacg atagcgctct tcaatcgcat
      121 gctggtaagc agataaagtc aattctcttc ctgcaaaggc actaactaac atgactaaag
      181 tcgattttgg caaatggaaa ttagttgaga aagcttctac cactttgaat tcatagccag
      241 gcgtaatgaa aatatcagtc catccgctgt ctgctttgat ttctccatta aatttcgttc
      301 caatcgtttc taatgttcga attgaagttg ttccgacagc cacgattttc ccgccatttt
      361 tacgtacttg gttcaatcgc tcagccgctt cttccgtcaa acggtagaat tcactatgca
      421 tatggtgttc ttcaatttta tctacgctga caggtcggaa tgtacctaac cctacatgta
      481 gtgtcagata gactaattca acaccctttg cttcgatctc atcaagtaat tctttcgtaa
      541 aatgcaatcc agctgttggc gctgcagcag aaccattttc tttcgcatag acagtttgat
      601 agcgatctgg gtcttccaga cgttctttga tatatggagg caatggcatt tctcccaatg
      661 attcaagaat ctctagaaaa attccttcat actcaaagtc aatgatccgt ccgccgtgtt
      721 ccaattcttc tttcactact gcttgcaatc tgccatcacc aaaagagatt cttgtcccaa
      781 ctttggcacg tttcgcaggt ttgatcaatg tctcccacgt atctccttgt gtattcgtta
      841 gaagaaggac ttctaaatgc gcaccagtat ctggtttttc tccatataaa cgagcaggca
      901 gaactcgtgt attattcata actagcgcat caccaggctg taactcttca atgatttcat
      961 ggaaatgttt atcttccatc tctccagttt tccgatccaa aacaagtaaa cgagaatgat
     1021 cgcggtcttt taatggtgtt tgtgcgatta attcttccgg caagtcaaaa tcaaaatctt
     1081 ctgttgttaa catatcgtca ctcactttct atcatgtgct tcatcattct atcatgtttt
     1141 tcgttctgtt ggcaaaatca gcactttttc acttctattt tttgttttcc taaataaaaa
     1201 aactacccta tttgtatttt ttcattgttt taggcatact agtaatagat agttcttcat
     1261 tgaaaataga aaaagaggtg gcaccatgat tgaatttcaa aatgtgtcaa aaatttataa
     1321 aggtggaaaa gtcgctgtag aggacgtcaa tctttcattt gaaaagggtg agttcatttg
     1381 ttttatcggt acgagcggaa gcggaaaaac gacgacgatg cggatgatca accgaatgac
     1441 tgatccaaca caagggaaaa ttttgattga tggaaaatcc atccaagaaa ttgatccagt
     1501 ggaattgcga cgtcagatcg gctatgttat ccaaagtatt ggattgatgc ctcacatgac
     1561 gatccgtgaa aatatcactc ttgtccaaaa attgttgaaa gtcagtcaag aagaacggaa
     1621 taaaacagct gaaaaaatga ttgatcttgt ggaattgccc cgtgagatgt tagatcgcta
     1681 cccacatgaa ttatctggtg gtcagcagca gcgtattgga gtcgttcgtg cccttgcagc
     1741 gaatcaagat atcatcttga tggacgagcc attcggtgcg cttgatccaa tcactcgtga
     1801 ttccttgcaa gaccttgtca aagatttaca agagcgtttg ggaaaaacga tcgtatttgt
     1861 aacccatgac atggatgaag cgattaaact agcaagccgt atcgccatca tgagtgaagg
     1921 ccgtgtgatc caatttgata caccagaaaa tattttacgt catcctgcaa acgatttcgt
     1981 agaagagttg attggagaag atcgcctact acaagccaag ccaaatgcga caagagtcgg
     2041 cgaagttatg ctaaatacag caatcacgat tacaccggaa aaatcattac aagaagcaat
     2101 caaactgatg agggaaaaac gtgtagatac gttgttagtt accgataatt cgaatgtatt
     2161 aaaaggattt atcgatgtag aaacgttgaa taaaaaacga ggaaaagtat ccagtgtcgg
     2221 cgacattttg aataaacatg ttttttacgt aaaagaatcc gcctatcttc gtgatacctt
     2281 gcaacgcatt ttaaaacgcg ggctgaaata cgtgccggtc gttgatgaac agaacaaagt
     2341 cgtaggtatc ctgactcgtg catcattagt ggatatcgtc tacgatgtga tttggggaga
     2401 agatcccgca actactgatg ttgcagagtc agctactcct gaagaatcta aggaggtctg
     2461 acctatgcag cagttttttc atcagcacgg ttcagaaatt ctctcaaaag gttttgaaca
     2521 tctttatatt tcaggacttg ctttgatcat tggtatcatc attgctgtac cgcttggtgt
     2581 cttactgaca cgttttccaa aagctgccac gattgtgatt ggcttaacca gtgccttgca
     2641 gacaatccct tctcttgctt tattggcatt gatgatcccg ctatttggcg taggtaaatt
     2701 acctgcgatt atcgcactct ttatttattc attattgccg attttacgta atacgtacat
     2761 tgggatgaaa aatgtcgatt ggaattatcg ggatgtggca aaaggcatgg ggatgactga
     2821 gttccaatcc attttttccg ttgaattgcc cattgctatg ccaacgatca tggctggtat
     2881 tcgtttagct gccgtttacg tgattgcatg ggctacactt gcctcttata tcggcgctgg
     2941 tggtttaggc gatttgattt ttagtggact gaataattac caaccagatc tcattttggc
     3001 aggtacgatc cctgtaacaa ttttagcact attggctgat tggcttctag gtctcttgga
     3061 acaccggctg acaccgatcg cacttagaga ggagaatgaa gaatgaaacg tatactaaaa
     3121 atgaccatgg ttcttttctc tcttcttata cttgcgagtt gttccttccc tggtcttgcc
     3181 agcaatacag atgaagacac catttcgatc acaggtggaa tcacttcaga agcacagatc
     3241 ttagcaagtc tagttgccgg aatggttgaa cattatacag ataaaaatac cgcaatcatc
     3301 aacaatctgg ctactacaac tatcaaccat caagcgatga tgaacggaga tgcttcaatt
     3361 tcagcggctc gctacacagg aacagattta acgactacat tgaaccttcc tcctgaaaaa
     3421 gatccgaaaa aagcgtttgc taccgtgaaa gatgaatttg agaaaagata cggtcaaacg
     3481 tggttcccgt cctatggttt tgaaaatacg tatgtctttc ttgttcgaaa agacaccgca
     3541 caaaaatacc atctatctaa agtcagcgat ctgaaaaatg tagcggatga attagtagct
     3601 ggtgtagata cttcttggat caatcgtaaa ggagacggtt atgacggctt ccaagaaact
     3661 tatggcttct ccttcaattc gatattacct atgcagattg gacttgttta tgacgcagtc
     3721 gaagcaggaa aaatggatat tgttcttggc tactctacgg atggacggat cgccagttat
     3781 gatctagtca tgttggaaga tgatcgtcaa ttcttcccac catatgatgc tgctccagtt
     3841 gtagacaaca agatattagc tgatacgcct catttaaaag aagccttaaa taagttaggt
     3901 cataccatca gtacggaaaa aatgcaggaa ttgaactacg aagcagataa taatctagtg
     3961 gaaccatcag tagtagcaca acgtttctta caagaaaacc actattttga agggaagtga
     4021 agcaattgga taaaatgaat gtctttcaac aatttttcta ttatttccag gaaaatggct
     4081 cctatatctt tgcacaattt atccgtcact tcctgatttc tatctatggt gtcctctttg
     4141 cagcagttgt cgggattccg gttgggatca tgatttctag gagacgtaaa ttagcaaact
     4201 gggtgattcg tttggcgaat atcatccaga cgatcccttc tctagccatg atctccattt
     4261 taatcattgg attaggcctg ggagtcaatg tcgtgattgt tactgtattt ttgtattccc
     4321 tcttaccgat catcaagaat acgtataccg ggatgatcca agtagacaaa aacatccttg
     4381 atgtcggcaa aggcatgggg atgactgcta gacaacgact attcatggta gagttaccac
     4441 tctctgtttc tgttatcatg gcaggcataa gaaacgcgtt agttgttgcc atcgggataa
     4501 ccgcgatcgg tgcattcgtc ggtgctggtg gtcttggaga tatcattatc cgaggaacca
     4561 atgcaacaga gggcacatcg attattttag caggtgcatt gccaactgca ttaatggcga
     4621 tcatcacgga ctggctttta ggtattttgg aaagacggct agatccagcc agccgtacat
     4681 cacgctgatg ttattgtaaa aaacaaaagc ttctgcgacc atttgttggt cgcaaaggct
     4741 tttttagttc tgtcattttt aaggcaataa tccactctga ttcttccctc cttatgggca
     4801 aagagttgct tttcttagct atttatccat tccgtatact ccaacttcat actgccaacg
     4861 ggttcatatc tgcatccacc gactaagttt ttttcttatc cgctaaggca ttttgccaat
     4921 ccattttccc atcactcgtc atggaattca taccacatga tctctaaata ctcgtctgct
     4981 tgttctttga attgggcatc aattcttaca tcctttggcg tggctttcat ttaagccttt
     5041 tccatcagtc ctcgattgtt cgatgccttc agctgcatca tcaaaactgg tgactgccgt
     5101 atcggtaact tcgatcatct tttatacaat cgggaacttg ccatcctcat ccttggctaa
     5161 aaacatatct agccattcca gcttctcgcc atgggaggtt tgcggttcct aaaaccggta
     5221 cacgattctt atggactgca tccgtcgcaa ctagacttgg cgatacgatg atccttcacc
     5281 agaagagcac ccccgtaaac caattgatcg atatattgcc aataagaaaa gacattggcg
     5341 taaaagatat cgatccctcg tgatgcattg ccgttgatac tgctattcat ggccgaaagc
     5401 gccacgactt taacttcttc cgtttgagtg acattcatgt tcggcaatgt cgctttggat
     5461 acccgctctg ctaaaggaac gacactggta ttgtatttcg tatctgtatc ttttccaaaa
     5521 gaccatgcca acgaatcctc tgggaaccaa taagacgact ccggttgatt gtccattgct
     5581 tttttcaaca tacttttggc tgtttctcga taaacgacat ttccaattgt cttcgcctca
     5641 ctttggcgat aatcgatggt cgttgccact gccaacacta acaacgatgc tccaatttta
     5701 ctgattttcc ttgtcacact tcttcctcct tgttttacat aaacccgtca acattccatt
     5761 cctaaactca aacaatgacc cttcaaaggt ggagatatag gaacaaatta aagaaatcat
     5821 gcaataaatc caagaaggtt ggttttagaa caaaaaaaga gtctcctttt tggggagact
     5881 ctttgttaac tatctaaaaa ggttggctct tctcacttca ctcataatgt gtccaggcag
     5941 aataaatttc tacaacttta ttttcctcat caactttgta aaccactcga tgctgtctat
     6001 tcagcctgcg tgagtatctg ccttcatgtg taggtctcag cttttcaaaa gactgcgtgg
     6061 gcatatatgg atcttccttc aatgtctgaa tcacttcttc aaattgtttc tttaaattcg
     6121 tttgcttgat ttttcttaaa tccactttcg cagagttttt gattgcgact gtatagttac
     6181 tcatcaaaga gcttcccaat caatatcatc gatattcgta aagctactgt cgtctttttc
     6241 gcggtctcgt actttatcta aagtacctgt ttgctcaaga aaaagggttt cttgaatcgc
     6301 tctccagtct tccagcccaa tcaatacagc attgtttcca ctacgatcac taataatctc
     6361 gatttcagta tgattttcat ttacctcttt caataactga taaaaatttt tacgagcagt
     6421 gctaggattc atcgttgtat tagccattgt ctctcctcct ttttctgata taattatagc
     6481 gtacttgatt aagtacgtca aaaaaataca ataaagcact taaattcagc aaacttttcc
     6541 tcttttttac atagagaaaa agaccccttt ttagggagga tctttgtcca cgctcacttc
     6601 ttactccttt acgactagcg gtagccaaac gtaaagtaat tggtaacaac gtatcatctt
     6661 tagcaaaggt cgaatccaaa gcctgtgagt ctatgcaaca acaccaatac acgaaggttc
     6721 ctcgttgcag tgtgacttga ttgatatctt gaataacctg aggatacgca cgaaagattt
     6781 gtaacggtta ttcaaaactg attttggccg tcaagtcttc tactgcctca aaaatgattg
     6841 cctctttcgt ctcctgtcat tcatgttcac tatcgatttg atacttgctt agaccgttgg
     6901 gtttgtgaat caccaattaa aaatggcact gagttatggt aacaaaaaat ggtcacttga
     6961 cgaggctgag attcctactt atgaagacac atggcactta agagtcgagg taaaggaaga
     7021 agctgaaaat ataggaggct gtacattatt tggcaaagga ttcggaaatt atgatcaaga
     7081 catcaaaatc aaaatgtttt acagctaaat aggaagaata ataacatttc atacgctgtt
     7141 cccatcttta atggcttata gagggcacct ttagctgaga ataagacaaa acagaccctc
     7201 tagcttcaat taagagctag agggtctgtt tttgatttta aaacttggtt tatttcttca
     7261 aatggtagct ataggtgctg acaacgatat tttcacgcca agacaatcgc aatcttaacc
     7321 gcaaacttgt ttggttatgg agaatattct gccagcgtct gtttggtaca aattgaggaa
     7381 tcaacacagt agttgtatag ttttgtttcg ctgcattttt acttacgata tctacataac
     7441 ggataattgg attttcaatc gagcgataag aagagtggac gattgaaaaa cggacatctg
     7501 ggaaatgctt tttaaattct gcttcgattt ctttttcttt ttcgacatct tcgtctagcg
     7561 aaacatgcat cgcaacgaca taatcaccga tcgaacgtgc gtaattcaac gcaccgatat
     7621 ttacccgtgt cacattcccg actaatacaa gaacggtatt cccgtcataa tcatgtagtt
     7681 ttgcatcatt ttctaaacga agctgttctg ctactttttt ataatgatca tggatcttat
     7741 aaaaaatgaa cataacgatt ggcataatga tgaagaaagg ccaaatgtcc cctaaccgat
     7801 agacaaacaa aatcgcaatg attgcatatg agatgaacgc acccgtaata ttggcaatcg
     7861 atttgcttaa ccatcttttt ccttcttttt tccatttgac gaccatccct gtttgagata
     7921 aagcaaatgg aatgaacacg ccgatagagt ataacggaat caagcgttct gttgagccat
     7981 ggaaaataaa cagcaatacg atcgaaccta gcgctagtgt gataatccca ttggaatagc
     8041 ctagtcgatc cccacgatct tgatacatgt gaggcatgaa tttatctttt gccagattgt
     8101 atgcaagaac tggaaaagca gaaaaaccgg tgttagcagc aactgctaaa atcagcgctg
     8161 tagcaaattg aaggacgtaa tacaaaatac catgtccaaa gacagcttta ccaatttgag
     8221 acaaaacagt gacttctttt tcaggaacga tcccatacca atagttgata aatgtgatcc
     8281 ccacgaagaa gaaacctaag atcaatgcca tcatcgtcaa tgtagcagcg gcattttttg
     8341 ctcttggctt cttaaagaat ggtacagcat tactaatcgc ctccacccca gttaaagagg
     8401 aagaaccaga agaaaatgct cgtaaaatca aagcgataga aacacccggc acagccgctc
     8461 ctggaagtgc agtagcttgc aatggcacag cacctgtcac gatattatat aaaccaacaa
     8521 cgatcagtaa cgagatcaca aggataaatg tgtacaccgg aaataatagg aacgatgcag
     8581 attccctcag cccacgaaga ttcagcatca tcagtagcaa aacgattgtc acagaaatag
     8641 cgacttgatg accgtagagt gctggcaccg ctgatgtgat cgcttcagca cctgctgaga
     8701 cagatactgc tactgtcaac atgtagtcga tcaataaaga gccaccggaa atcaagccag
     8761 cattctttcc aagattctca ctgctgacga catatgctcc cccgccatga ggataagcat
     8821 ggatgatttg acgatatgat agcgttaatg aaatcaataa aataataaca aaagcggcaa
     8881 tgggtagcga ataccagatg gctgcagcag acaaagcgac taaaacgaca acgatttgtt
     8941 ccgtaccata tgcaatagat gataacgcat cagacgacaa taatgccaaa gcagcaaatc
     9001 gggttaattt gtgctcatca ttttcagcag attttaaagg cttacctact aacaaccttt
     9061 ttaagtaatc caatttctaa actcctttac acacaatttt acttcaagtt ttatagtcga
     9121 aaatttatag taaacaagat gttatagtac gctcactgac cttaaaagtc aataaacttt
     9181 aagaaaataa ttggaaaaaa acagaaaaat atcaagcgct ttttcaaacg ctttaataca
     9241 gcaaaaatct aacatttttt tatgggcttt ttctttgaat tctataataa aaggatagaa
     9301 cttgacttag aaaatcaagt tctatccttt ttgatatctt aacttttgga agagagatgt
     9361 aaggctgctt tctacccatc attcttacta ctcgaagcat agcgcagttg tcacaacctc
     9421 ttgataaacg gtgtttaaaa gcttgcatct gcggtaataa gcccaaccaa attaaaaaca
     9481 taagaagctg tttttatttg gtcgttctta ttacttgatg cagagcagct tttttacaac
     9541 ctcttggtac acggtgttca atcagctgac cctcggtatt agctcaaaaa aacggcaaaa
     9601 tatgaggaac tatttttcca tttttttctc taatactcag gtcaaaacac tgatttcaca
     9661 acctcttttt ttaatgaaaa atatggctct catgcgccgc ttctttgaat ttcgtcattt
     9721 tttcttcgat gaacggatag attgccgttc ctacgattcc aaagacaaca aacaaaccga
     9781 tcatgatcca gattgctttc gtagcatttg gccaataaat tcctcctgca gattcccgta
     9841 acaagtttac cgcatgagta aatggcaaga acggattgat catttggaag aatttccctg
     9901 agacttggat cggatagttc ccgcctccgc cagagatcga cagtactaag atgataatag
     9961 cgatcccttt accgacatta tcgaataatg cagccaagac atagacgatc atcatgaacg
    10021 ctaaggcgat caagacagca aatgacacgc tgtagaccgg attttggaca tctactccta
    10081 gtaagaaaat attccctaat gtaacgatca agctttgcgc aatcgccatt gtcaaaaatg
    10141 tcagcatacg agcaacgaat tgttctcgtt tcgtaaaatt gtttcggtct ttctttccta
    10201 aatagtattc tgtcgtagca acacttgaaa gaagaacagc gccgacccac agacatagtg
    10261 cagtataaaa cggggtgcta gctgaaccgt tatttgcgat tggataaagc gcattggttt
    10321 gtagctcaac aggttgtgta aagaagtcac tttcttttgt tgcgtctagt ttcaataatt
    10381 tgatgacttc gcctagatcg acttcttgtt cgccttttcg gatcgcgtct gctgcttttt
    10441 ggataccagc tttgatattt ggccagtcat tgttgatcaa gtccgcagca gcgttcacag
    10501 ctgtttcgac ttctggcatt ttttcattta ctgttgtcaa tgtaccggtg atttcatttt
    10561 ttagtgctgg ccaatcattt tggataaaat cagcggccaa tcctaatttt tgctgaatga
    10621 tcggtaattc attgttgtat aggtctgccc cttcattgat gccattgacg atggtatcca
    10681 tatttccatt cagcattgta ttggcatcat ggatttcttg tccaattgca ggcatttctt
    10741 tttgatattt ttctaaaatt gccactgcat tcgttacagt tgctttcgtt gagctgagaa
    10801 gcgaatcaaa gtcgatctgg tccgctttgc tcagtgcgcc ttgtgcagtc ccaatcgtat
    10861 cgatgacttg gtctagtaga gaagtgacag tggaactgat ttgacctgta ttgataccag
    10921 caatgatgcc attgatatta ttaacaacgg catcaatttg atctagcaat tcatcaatag
    10981 ccttcgtgtc ttcattttga acagctgtgt tcaaagcaga taggcggttt tgcagattgc
    11041 ttagcaaggg ttttaattga tttagctgat caataattgg ctgtaatttc gtatttccag
    11101 cacttgtttg caatttagtc aggaactcga ccagtttatc gattgcattt tgttgttgag
    11161 atattccgtc aataaagccg ttcaatacat tgctgatgtt tttcttttca tcatcagtca
    11221 gcttaccatc ttcaatagct gttcttacag tatctattaa cgaacctgtc gttgttgcca
    11281 cttgtccaat tgacttcaat gtaacatcta cactgtttgt gatgcttggt atcgcatctt
    11341 tcagctgaga ggcacctgat tttgtttggt ttgctagatc acttgcctga ttttctaaat
    11401 ttttcacatc tggcaagata tcttgtactt gttggatgat cgtcaagcct tgttttgctt
    11461 catcgattcc ttggttcatt gtctcttgga tcgaagcaaa atcgccgtcg atctctgcta
    11521 gttgcttacc ggcattttgg atctctggga ttttttcttg caaatcaagg atgatttttg
    11581 cttgatcttt caactcaggc attttgtcat tcaatgcaac gactttttca cccatctcat
    11641 ctactttagg gatgtaatcc acgaattcat ttgctttatt cagtttttcc ttgatttcag
    11701 gtagttgact ttgtaattcg aggacttgtt ttgtgtagcc gtcgatcgtg tccaaatttt
    11761 catctgttga taaaatcata tctttaactt tattgatact tactaggttc gtatcgatgt
    11821 cgtaacctat ctcattgaat actttcaata aagtcgaact ggctgttttg ataaattcat
    11881 ttgtgatttg cgattggatc gaacttgctc ctttatcggt gattttcggt gcaatcgcat
    11941 tgattttttc atttaccgta tattcgattt ttggtttctt gatatcacca ctagtaaaac
    12001 tcagcagatc ttctgagaaa tcctttggca agtaaatacc tgcgtaatac tttccggaac
    12061 ggactccgtc ttctaattgt tcttttgaat caacgaattg ccatcctaat tgtttatttt
    12121 tatgaagcga ttcgatgact tgctccccaa tggccacttc tttaccttga aactctgctg
    12181 gcttgtctgc actgtaaaca gcaattggca gctctccagt atttccatat ggatcccata
    12241 atgctttgat gttaaaccac gcatatagcg aagggatgat catgatcgcg atgatcagaa
    12301 gtgttgcaat cgggtttttg aaaatccgtt tccagtcaag caaatataat cgaagcgtat
    12361 ttttgattga ctgcatagtt ctcccccttc ttcttttttc agctgaatta ctttaccatg
    12421 tatttcatac ttttttcaat cggctttttt caaaaaagtc gaatttttgg acatatcacg
    12481 gcaattgtct cattgtaatc tcttacatat tgagaaataa ttaaggatta cagcctttac
    12541 tttatcatga aataaaaggg aaagataatt ttatgccaaa gtttttatct attatacgta
    12601 tacgcaaaaa agctaaaaca ttttttgtct ttgcccctac aaaaatgttt cagctttttt
    12661 cgttttttat tcctgtattt cttatttttc gaatgacagg atgattttcc cagcaggagg
    12721 atgtccttca actagctgat gtgcttggat gacatgctta agtgaagcag acagattcat
    12781 tgaaataaaa acatgaaagg ctcctttttg gtaggctttg attatgccag caaaggcttc
    12841 tgcatctaga tattcctttc ttggaacaaa cgattcataa aagccttcct ttttttgccg
    12901 caaatctaga tctgggaggt catttaatgc aacatacctg ccgcctggtt tcatgatctg
    12961 gatgccggtt tctcctttga tacttccttt cgtcgcatcg attacaaggt ctgcctgatc
    13021 agcaaattgc agacctggat ttgttttatc ataagcagca aatgctgaag ctcctaattt
    13081 ttttaccttt tcctcatttt tactggatgc actggttaag attcggattc ccttttcatg
    13141 gagaagctgg atcagacttg acccgaccgc acctgatgct cctagtatca ttacagtatc
    13201 tgtcggctgg atttccgtca aatggttgat tagattataa gccgtaattc ctggcgtgac
    13261 cattccggct gcttcttccc aactcatttt atctggaatt tttgctactt ttgctgatgg
    13321 caacacgact tcttctccgt aagtcccgcc gactgcatgg acagctactc gatcacctac
    13381 atgaacagtt gtgacatctg aaccaatctc tgtcacaata ccagcgccat cattacctgg
    13441 tacataaggg aatttcaatg ttcgtatctc tttcatttct cctaaacgca aggcaacatc
    13501 ataaggattc acactgaatg cttttatttc tacacgaaca tgtccagaac cgacttctct
    13561 gggatgagca tcgatttctt caaaaacatc ttgtgcttct ccgtaaccgt taattgcaaa
    13621 tcttcgcatg gtcaccatct ccctttttct ttaagtttac gtttatgcct ttattttgac
    13681 aaaaaaaatg tcttttcgtt ttggcgcatg attcaaaaca aaatagttgt cttttttcgc
    13741 gtaacgtgtt aaattattta tctaaaagcg taaagattac gatttacgct aataaaaaat
    13801 aattggagga atttgttgat ggctaaaaaa tcaaagattg ccaaagcaaa aaaacagcaa
    13861 gaaacgattg aacgctatgc tgctttacgc caggaattaa aagcgcaaaa agattacgaa
    13921 ggcttgcgta aacttccttt agatgctcgt ccagaacgat tgaaaaatcg tgatttaatc
    13981 gatggacgcc ctcgcggata catgcgtaaa ttcgggatgt cccgtataaa attccgtgaa
    14041 ttagcacata aaggtttgat tccaggagta aaaaaagcca gctggtaatc caagtctggc
    14101 tgtaatgtaa aggaggaggg cgcatggacc actccttgga tcatcaaaaa agatacgttc
    14161 gcttcttcta gcagaaatgc tggtactaga agcagacgta tcttttttta cgcacagctg
    14221 gtcctttttt atatgtaaag gctgcatggt tacttcgcta tatttattta gtaacaggag
    14281 tcagtgcttc gatacccaca ctaattttca atgctcggtc aacttctgcc ataatgggtc
    14341 gatccaaatg gcagaccttt tctttcaatc ttgatttatc gatcgttctg atctgctcca
    14401 acaggataac ggagtctctt tctattcctg ttccagtagc tttgatccca atgtgagtcg
    14461 gaagcttagg tttagccatt tttgccgtta tggccgcaac aatgatcgtc gggctaaaat
    14521 ggttacctag attattttga ataaccaaaa ctgggcgtgt tccgccttgc tccgatccca
    14581 cgactggaga aagatcagca aaataaatat ctcctctttt taccatagga tcctccttat
    14641 tcttgatatt ctcttggtat ccgctgtcct aatccgcaag ccacttcata gtggatcgta
    14701 cctaattgat ctgctatatc ctgcatagtg atttctttgt ctgcattttt gccgataagc
    14761 gtcacttttg ttccgacagg aaattcttga ggcaatcgga tcatcagttg atccatacat
    14821 acacgcccaa tcgtttcaca gtagttccct tctaccaata gagaaaaacc ctgcatcttt
    14881 cgtggccagc catctgcata accgatcggt atcgttccga tccactctgc ttcaggagtg
    14941 atatatgttt ctccatagcc gattccttca cctgctggga gttttttgac ttgaatcaat
    15001 tcagaaacca gctcaagtgc tggctgcaat ggataaactt ccggtagtgc gtgcccagag
    15061 ggattaagtc cgtacattgc tactccataa cgaatcatat tgccgattgt ttcatcatgc
    15121 cataaagccg ttgcactatt gctgacatgt acatatcgag gaagttcggg aagttttttc
    15181 agcacttcta taaagcgttc tttttgcaga ttccaatatg tatcatctgc ctgatctgct
    15241 gtagaaaaat gggtaaataa accttcccat tctaatacac gactttcttt gatgaatgca
    15301 gctgcctctt ttacttcttc aggtgtacaa aatccgatac gacccatccc agtgtctgct
    15361 tttagatgaa tcgaaagagg cgtctctagc ttacttttct ctaaaacagc agctgctgct
    15421 tgcaaccatt cccgtgtacc tgcagttact gataaatcat gagcaacagc tacagtcagt
    15481 gcgtcgtaag gaaccatatt caagataagg atgggctgag taaatccagc ttctctcaac
    15541 tcgactcctt catctaaatt tgaaacacaa aagcccgaag ctccacctgc aactgctgcc
    15601 tcagctgttt caatagctcc atgaccgtat ccgttcgctt ttactactgc aaacaattct
    15661 tttccttgcg gaagtcttgc aacttcattt gctacatttt cagttatagc ttttttatgt
    15721 atcactgctt tcgttgggcg gtgccaagcg acaaccatcg tttttccttc tttctagtct
    15781 tccaaaataa tttgtgcaaa agctgtttca tttgtatgag taatactgac ccatacattg
    15841 ccttcatgag gtgaacgcgt cacaacaggc tgaccatttt cattttttaa aatctcgaca
    15901 tcttgaaagg taacttttcc gatcccagtt ccccaagctt tagagaaagc ctctttgcaa
    15961 gcgtaacgcc cgcctaaaaa ttctacttgg cgatgaaaag gcaaggactg gaatagtttc
    16021 atttcatcag aggtcaagat tcgtgcaatg aattttggtt tttcttcgat cagccgagtg
    16081 atcctaggaa gttcgactgc atcgatccca attcctttta tcatatgctt ttctcttttc
    16141 aataaattta gaacactctc attctaccaa attataacca ttttgccaca aataagtcca
    16201 caaataacaa aaatgaaagt ttctcttaaa aaagagaaac tttcatttta tgtttaatcg
    16261 ttatttgaac ggattacaaa tccgcgtttt ttatcattgt gacgtttacc gccatctttt
    16321 tggctgttat tatttttgct ataaccgcct tttgatttgt ttccacgata attaccgccg
    16381 tcacgacgat tacggttgtt tccgccacca cgtttgccat ttttattgta tccttttttc
    16441 tgcattggca atgggcgttc tggtgtgatc ttcactggca ctgcatcagc tggatctttt
    16501 gctgtcgttt ttagcaaaag tgcaactaaa tcttgtgcag aatattcttc taataattta
    16561 tctgctgttt gcaggtattt atctagacca ttttctgcaa gttttgtttc gatttgttca
    16621 actgcagcac ctaattgacc tttgaatgct tctttttcgg ttggtggacg taaagtcgtc
    16681 atccgttttt tcgtcaagtt ttcaatcaca tgcaagtagt ccatttcatt tggtgtaacg
    16741 aaagtcacag acataccgcc ttttccggca cggcctgtac gtccgatacg gtgaacgtag
    16801 ctttctggat cttgagggat atcatagttg tacacatgag tgacacctga aatatctaat
    16861 ccacgtgcag caacgtctgt cgctacaagg atatctaaat gaccgctctt aaatgaacgc
    16921 aatacgctca ttcgtttttg ttgagacaaa tcgccatgga ttccttctgc acggtaaccg
    16981 cgtgcttcta atccgcgtgc caattcgtct acacggcgtt ttgtacgtcc gaagacgatt
    17041 gttaattcag gtgtttgaac atcaaacaag cgagtcatga tatcgaattt ttcgtattct
    17101 tttgcgcgga catagtattg atcgatcaag tcagctgtca tttctttcgc tttgatcttc
    17161 acatgatgtg gatttttcat gaatttaacg ccaatattct tgatagctgg cggcatcgtt
    17221 gctgagaaaa gtaatgtttg tctttgatca ggaacttgtg aaatgatttt ttcgatatct
    17281 tccaagaagc ccatattcaa catttcatct gcttcatcca aaactaatgt ttgaacggtt
    17341 ccaagtttca atgtgtggcg gttaatgtgg tcaagcatac gtcctggtgt acccacaacg
    17401 atatgtggac gatctttcaa gccacggatc tgacggccaa tatctgctcc gccgtaaacg
    17461 gcttgtacac gtactttttt gtcgcgccct aaacgatata attcttcttg tgtttggata
    17521 gctaattcac gtgttggtgc gataactaaa ccttgtaatt cgtgacgatc tggatcgatt
    17581 ttttctaaca ttggtaatcc aaatgcagct gttttccctg tacctgtctg tgcttgtcca
    17641 ataacgtctt ttccagctaa tgctagtgga atcgtttctg cttggatagg cgttgcttct
    17701 tcaaaaccag cgcgttcgac tgatttcaac aattctggtg ataattctag ttctttaaat
    17761 ttcaaatgaa tcctcctata tggttgttaa ctgaggatgt agcttttttg ctaccccgtc
    17821 gatttgttcg gtcaaagtgt attgtttctt tttgacagtg gccacgcacg tttttatcca
    17881 ttcttagccc ctgtggcacc accgaaaaat cactttgcga agtttaggca ttagaaaagc
    17941 caaacgggtc gcgttcagct ttatcattat tatgacatct ggcttcaaca agttgtttct
    18001 atggcaaaac cagtccaatt tctcttcatc tttcggcaat aggttattct aacatagttt
    18061 ttcgttttct gcaagtttac agatttttat ttcatttgct gaagttgttc taccacttca
    18121 aataagccca tgctgttgct gccttttagc ataatactat ctgttgcttc aagattttgt
    18181 ttgatagcat caatcaattt attcttttct ttttccaaat agaacacagg tagttggggg
    18241 tatttttggt tcaattcttc ttttagtgca tgcatttgtt ccccataaag gaaaatcatg
    18301 gcgaatttct caggatcgat atgttcactc atttgcgcat gcatatttaa agactctttc
    18361 cctaattcca gcatatctgc taacacagcg attctgcgtc cttttgttgg cagattttta
    18421 aaagtatcta ataccagtcc catggctgtt ggatttgcat tgtagacatc gctcaaaata
    18481 gctgcaccat ttcctgccgt tagccattcg gttctgtttt gagtgataga aacatgggcg
    18541 agcccttggc gtatctcagg tatggacagt ccaaagaagc gcccgatcgt atacgcaatc
    18601 aaagcattcg ttacattata acttccaggc agcgggatcg taaatgtttc tccttctact
    18661 acaaaatcgg tttgtgcttt tccttttgct gtcacttccg catgaacatc gccatttcca
    18721 ataccgaatg ttgtgactgt ttgtactaat gttgccgtta aaggtgtcag caacggttca
    18781 tctgcgggca caacgagtaa tccgtctgat acaagtccgt cagtgatttc cattttggct
    18841 ttagcgattc cttctcgcga cccaagattt tctatgtgtg cttcaccgat cattgtgatt
    18901 gctgcagctt ttggttgagc cataagtgaa agttccgtga tttcattggc gtgatccatg
    18961 cccatttcca aaacgatctt ttctgtatct tggggcatgt gcaaaatcgt gtaaggaaga
    19021 ccaatattat tgttgtaatt tccttgcgtc ttatatgttt tgtatttttc agacaagaca
    19081 gacgcggtta gatctttcgt ggtggtttta ccattgcttc ctgtaattgc aacgacttct
    19141 gcgcctactt tttccaagta ataggttgcc aattgctgca tggctttcaa aggatctgct
    19201 acaggaataa ctggaaaatt ttttggagct tgttcaacag gcaagctcca aaatgaagca
    19261 gatgctccgt ttgtgatcgc ttgctggata aattcatgtc catctcgcgt accagcaaga
    19321 ggaacgaata aacttccttc ggttatcttc cggctgtcaa attcgacatt ggtaatcttt
    19381 gtcagtgcag agcattcgct gcccacggct tgtgcaattt cttgtattgt tagattcatt
    19441 gagatctctc ctaaaaaagg ttgtgaaaaa agcgtttggc ctaaacggcg ggttcgcatg
    19501 actctcactt ccaagtaaat ttctctattc gtatttagaa gctagaatga acgcggttac
    19561 gcaatcactc cagcctcttc tttatttctc tttattcatt tttttcaaaa aaagattgac
    19621 gctgatggta tcgattcatt cctaactgga tcagttcttc aatcaaatca ccgtatttca
    19681 agcccatatt ttcccataag agtgggtaca tactgaactc cgtaaatcct ggcatagagt
    19741 ttaattcatt caggaataat tcatttttat ttgtcaaaaa gaaatcgcac cggctcaatc
    19801 cgcttccacc taacatcgtg taagctaact tcgcgtactc ttgcgctttt tgataaactt
    19861 cttctggcac ttcggctgga atctgcattt cgattttatt attgatatat tttgcttcat
    19921 aatcatagaa tgctacgtct tttacgactt caccaggcaa agtcgtccga acgtcttcat
    19981 ttcctaatac agcaacttcg atttcgcgcg cttcaattcc ttgttcaacg attgctcgag
    20041 aatcatactg ataggctgtt gctaaagcat tttgcagctc ttctcggttt tctgcttttg
    20101 taatgccgac actagaaccc atattcgccg gtttgacaaa catcggataa agcaaagaac
    20161 cttcacattg atcaaatact tttttaggat tttctttcca ttgattctta agtactggta
    20221 cataaggaac ttgcggcaca ccagcagctt gtaaaatata cttggtcatg attttatcca
    20281 tggcacatgc actggtcaat acgcctgcgc cgacataagg catattcaat gtctctaaga
    20341 agccttggat cgttccatct tccccgtttg gcccatgtaa aactggaaaa acgatggctc
    20401 cttcttcttt gatttcgccc ggattgatca cttttcctgt aaagccttcc tctgtctgtc
    20461 cacttgggtc ccatgaaaga tgcaagacat ctttgctggc aggtttttct gttagtaatg
    20521 gacctttgac ccattgtcct tcttttgtaa taaatacgag ttgaacttgg taataattat
    20581 aataaatggc atttaaaact gaaaatgcgg aaagaatgga cacttcatgc tctgcgctgc
    20641 gtccgccata tagtaaagta atcttcaaaa gattgtcctc ctgtattcta aatcgttcag
    20701 tgatttactc tcatatttta gcacaaaaca aaaataaacg aataacttat ttataaaaaa
    20761 acgagccagc ttctaaaaga acgagcgtca tttatttttt gtcagctaga ttatttgtcc
    20821 cgttttttat aaaaagttat gataaagaaa aggagggatg atgatggcgc aaacaaatcc
    20881 acgcagccgc ttggcagaaa tcattcgagt gttcatcaat tacaatgtag tgccaaactt
    20941 tgtacagcaa aaaaatcccg aacaggtaaa aaaagccttt gaagaactag gccccacctt
    21001 catcaagata ggacagatgc tttctgttcg agaagatttg ctttcttctg ccttcactca
    21061 aacattcaaa acattacaag atagtgtacc tagcgacaca ttttcaacgg tcaaaaagac
    21121 gatcgaaaca gaactttctc tttcattatc agatatattc gatgattttt caaaatcgcc
    21181 ttttgcctct gcttctatgg ggcaggctca tcgtgccaag ctgaagaacg gtgacgcggt
    21241 agtcgttaag atccaacacc ctaacatcgc cgaagagatc cgacttgatc ttcaactatt
    21301 tgaacgagcg atccctttga tcaaatacat tcctgaaact agcgtagttg atctaaaagg
    21361 ggtactccaa gaagtaaaac gttccttgat caatgaaatg gacttcttaa aagaaagtca
    21421 aaatggcgaa caattctatc aaaagaacaa tggctggaaa gagatccgca gccccaagat
    21481 ttatgacgct ttttgttcga aaaaagtgat cgtgatggaa gaaatgtctg gtaaaaactt
    21541 gaatcattta atgaacgccg aaaacaaaac tgaaactttt atcactggaa ttcaaaacaa
    21601 gcagctgaaa caagaagttg caaagctttt agttgagaac tttatgaaac aggtgtttga
    21661 tgatggtttt ttccatgctg atcctcatcc agggaatctg ctattccatg tactaacaaa
    21721 agaagaacag acacaagcta gccgaaaaac tgaaacagtc catgaaaaag agttcggttc
    21781 ctttgctttt cgagcctcca cttctgcaga agaccctgtt gcgccatata ccatcaacta
    21841 catcgatttt ggtatgatgg ggcatctttc tgcaggactt aggcaaaaac tcacacaagc
    21901 cgttttagcg ctgtatacga aagatgctta tcgaatcgaa aaagcggtcc ttcgactttg
    21961 tcagcaagaa ggctcgtttg atgaaagtcg gttccaccaa gaactgacaa gttttcttga
    22021 acagtattat gattctccta ttgatgaaat caacttgcaa gaagtattca cacatgtcgt
    22081 gacgatttgt catcaaaata atctgcagtt cgatcgtgat atcacgcttt tgctgaaagc
    22141 atttgggaca ttagaagggg tgatccgcgt cctcgatcct gaagtttccc tcatggaagt
    22201 cgcttcgcct tttgctcaac attattttct cactcatctg gatgtagaag atacattgaa
    22261 acaaagcgga ttagacttat tggaagggat gaaggctgcg cctaagatcc ctcaacagct
    22321 ccaccatcta ttagaaatgt ggacttcggg acaaggaaaa gtcaatttgg aattgaaaaa
    22381 gcaagacaaa ttattgagca ggatcgaaag tatgatcaat cggcttgttt tcggtatgat
    22441 tttagctgca ttgatcgtag ggtcctccct gcttgtccaa gcagcacctg tagaaaacgc
    22501 agaggtcgtt tccttattag ggatatttac gtatgctatt gccgcattcg tcattatttt
    22561 tttggcaatc gatgcattga tccaaatgta taagaagagg aaaaagtaga aaaaggttgt
    22621 gacagaaaga atcagcttca agaaataaga aggggtttta cataaattgt ttctcaaatt
    22681 tttgtgaaaa ttcggcttat ttttcgaaga ggctacttct gaaacaccga gaataaaaaa
    22741 tgtgaaaaag ctgttctgca cccagtaata agaacaatca aaaagggaac atggaacaca
    22801 tttatcctgt ttccctgttc cctttttgat gtattcgagc ataaataaaa taccttcgtt
    22861 acctactatc ttctgtactt ggtaaacctt agtcaattgc cttttttaac gcttgacgaa
    22921 aagacatatg atctttctcc gtaaagggtt ttggaccctt tgtccttatg ccagcttttc
    22981 ttaactttcc actatgataa cgttgttcta gaagcgtgcc gatattcgct tcgtcaaatt
    23041 cttttccaga gtgatggaac actcgcacac ccttcggcaa tacaagtgaa gctaaaccat
    23101 aatcttgcgt gatcaaaaag tcattcttct taaccatacc gacgatttta taatccgcac
    23161 tatcagctcc gcggtctacg tagacgattt ggacatgatt agcgtattct ttggtcgtat
    23221 aatggtccac actggtcacg ataaccacgt caagaccata ggattctcct aattttatga
    23281 catcttcttt tactggagaa ccatctccat caatgaatag cctcattctt tttcgccttc
    23341 ttccataaat gataaacagt tactaatccg ctcagtaaaa gaccaacatt gatccatttt
    23401 gccaagataa gcagttgtac actttctatc ggcactgatt catggttcag cgtgatcaat
    23461 aatagatgga ttggctctcc catttctttt gctaaaacaa acaaaagcgt catcaataaa
    23521 aactggtgga tcacactccc tttattttga gtagtatact tgacaacgat ccggcgatcc
    23581 attggaatag ctgtatcagt ttgataatat tccttattta gccagctgcc tgttactacg
    23641 tgccagaaac taagcagaaa gacacctatc gcaaaaccat ttggaatcaa gaggaccaat
    23701 aaagaagaac tcagtccaag caattgcata gccaatggag accatgttaa acgtttcaaa
    23761 atccatggtc cgactatttt tgctgcaatc aagcctgctg cataaggcaa atacataaaa
    23821 atcgaaagtt tttctaatcc gtacagtatg ccaacataaa aactgctaaa taaaaaaagg
    23881 aaattcccta gcattccatt tagaaaagta aacagattta gccagcttgg caacttccat
    23941 tccttcttct ggtgtcctaa aacaaacacg aacaagatga acagcagcaa gaaaccataa
    24001 atagcaagat caaaaagcct ttcatcgaat aacaatcggg catttctcaa aagaaacaat
    24061 aagccaaaga atatcaaaaa taaaacaagc tctcgcgtag ctaccagatt tcttttgatg
    24121 tctttgaaat ccagttcgta acgcggataa tgactaaccg tatggtaggc catgacgtaa
    24181 aaaagtgtat aaatagtaaa gcttgctgca atctgagtcg gtgcaggcaa ctcaatcgct
    24241 tgatacagga gaaatagcca gatagctgca aataagtact ttttcccatc catattgata
    24301 aaaccttgcg tcttttcgtg aaaattgacc gtggtattag caggtacaag ccatgctgca
    24361 ctcagcccta gcaaaacact tgaaaaataa aataaaggaa aataaaatac gcctaatatt
    24421 ccaagcaatg aaccagcacc accaatcagc agagcgatca tcagcaacgt gtaactatct
    24481 agaccaaatc gtagactgtt gactaaaaat agtccagtca tccgaaaggc ataaaacagc
    24541 gtaaatggca aaatcgtcag ccaattatgc gagtctgtta gtcccaaaaa taaaagataa
    24601 ggaataaaaa taaccgtgtt acttaagata aagggcgttg tttgtgtaaa attacgccca
    24661 aatcgtttga gtttttcgaa catgacaatg gctccttaaa cagtcttata actaatctgc
    24721 tcttcgattt tagcattaaa ggggaaataa accaatttta cagaatatat tcttgtaaaa
    24781 aaaaatacag aaagaagcat aagcttcttt ctgcattttt acggtacttg attactcaag
    24841 cagacaagcc cttctccaca aaagtcttgc ccgacacccc tgcatccggc aggtgataaa
    24901 gatagaaatc aattatcctg tgcctccaaa atcaattagg agctctgtaa accagagtcc
    24961 ttctcgaccc gtcgcataaa tttactttaa cacagttcct atgtttatgc gagagctttt
    25021 ttcattttat aatcgaccat ttgaaatcct tgaccgatat ctgaaataag ttcttctgta
    25081 atctcaaatc cttcatgctt ataaacctcg attgcttgat gattcccctg attcactcgc
    25141 aaaaagatct ctctttcctt tgtttgcgca gcaagttctt cataccagcg aaaaactgaa
    25201 gaagtcaatc cttgaccacg tactttattt agcaaatata atttacttaa ataaattttt
    25261 ccatttatct cttcataagc agtgtaaccg acagtctttt cttcgctttt taataaaaag
    25321 taggacacac cttctgtcag ttctttttga atctgttttt ttgactgata agttttcagc
    25381 atgtaatcca cttgtttttg accaatgatc ggcacaaaag cttccggcca tacttcttgt
    25441 atgactgcca tcagctcatc cagttcattt tctgttactt ttattttttc catacaccca
    25501 cgtccttttt tacattataa atgaccttgc gcttgatgga ataaaaagag catgatcatg
    25561 ctatacacac ccaccgacca tggtttcaag aaaatcacaa tctgcataaa ttccctaaaa
    25621 gataatttcg tcaaaccagc tactagacag atcaagtcgt ctggcgcaaa gggaagcagc
    25681 aaggtaacaa ctagtacttt tttaatatct ttcgtttttc ttgtcagcaa ttcatcaaat
    25741 ttctgatact tttttggcga taaaataagc tggacaaagg ctacgccata gtaacggaca
    25801 agcaaaaatc cgattgcttc cccaatcact aggccaatac aactatataa aagcccaaat
    25861 ccattgccaa acatcagcat gcccgctact gaggagatcc ctcccggcaa aataggaatg
    25921 atcacttgga tcacttgcaa cagaacaaat atcatcactg catacttgcc aaattgctgg
    25981 ataaacgctt gcaaagacgt gctcgatcga aaaatcccat gatgataagc ataaagaatc
    26041 aacacaaaga aaaaaaacag accaataatg ggcatgatct gaagacattt ttgtaaaact
    26101 gatccttttt tagacatcta tattccccac atcttttttc atttattaaa actgcctc
//
LOCUS       DADQDV010000039        25807 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.039, whole genome shotgun sequence.
ACCESSION   DADQDV010000039 DADQDV010000000
VERSION     DADQDV010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 25807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25807
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.039"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            126..3653
                     /locus_tag="J8S10_001681"
     CDS             126..3653
                     /locus_tag="J8S10_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HAZ9630267.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3650..7372
                     /gene="addA"
                     /locus_tag="J8S10_001682"
     CDS             3650..7372
                     /gene="addA"
                     /locus_tag="J8S10_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HAZ9630268.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7441..7782
                     /locus_tag="J8S10_001683"
     CDS             7441..7782
                     /locus_tag="J8S10_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAZ9630269.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8091..9134
                     /gene="pheS"
                     /locus_tag="J8S10_001684"
     CDS             8091..9134
                     /gene="pheS"
                     /locus_tag="J8S10_001684"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HAZ9630270.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9139..11559
                     /locus_tag="J8S10_001685"
     CDS             9139..11559
                     /locus_tag="J8S10_001685"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HAZ9630271.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11729..12739)
                     /gene="trpS"
                     /locus_tag="J8S10_001686"
     CDS             complement(11729..12739)
                     /gene="trpS"
                     /locus_tag="J8S10_001686"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HAZ9630272.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            12993..13730
                     /locus_tag="J8S10_001687"
     CDS             12993..13730
                     /locus_tag="J8S10_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAZ9630273.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13744..14559
                     /locus_tag="J8S10_001688"
     CDS             13744..14559
                     /locus_tag="J8S10_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HAZ9630274.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14572..15219
                     /locus_tag="J8S10_001689"
     CDS             14572..15219
                     /locus_tag="J8S10_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAZ9630275.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15235..15891
                     /locus_tag="J8S10_001690"
     CDS             15235..15891
                     /locus_tag="J8S10_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAZ9630276.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            16053..16874
                     /gene="racE"
                     /locus_tag="J8S10_001691"
     CDS             16053..16874
                     /gene="racE"
                     /locus_tag="J8S10_001691"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HAZ9630277.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            16877..18232
                     /gene="rph"
                     /locus_tag="J8S10_001692"
     CDS             16877..18232
                     /gene="rph"
                     /locus_tag="J8S10_001692"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HAZ9630278.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            18233..18751
                     /locus_tag="J8S10_001693"
     CDS             18233..18751
                     /locus_tag="J8S10_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HAZ9630279.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            18858..19358
                     /locus_tag="J8S10_001694"
     CDS             18858..19358
                     /locus_tag="J8S10_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAZ9630280.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(19638..20558)
                     /locus_tag="J8S10_001695"
     CDS             complement(19638..20558)
                     /locus_tag="J8S10_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HAZ9630281.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            20723..21736
                     /locus_tag="J8S10_001696"
     CDS             20723..21736
                     /locus_tag="J8S10_001696"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HAZ9630282.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            complement(21846..22601)
                     /gene="fabI"
                     /locus_tag="J8S10_001697"
     CDS             complement(21846..22601)
                     /gene="fabI"
                     /locus_tag="J8S10_001697"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HAZ9630283.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            22821..23261
                     /gene="fabZ"
                     /locus_tag="J8S10_001698"
     CDS             22821..23261
                     /gene="fabZ"
                     /locus_tag="J8S10_001698"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HAZ9630284.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            complement(23376..24137)
                     /locus_tag="J8S10_001699"
     CDS             complement(23376..24137)
                     /locus_tag="J8S10_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAZ9630285.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            24326..25420
                     /locus_tag="J8S10_001700"
     CDS             24326..25420
                     /locus_tag="J8S10_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HAZ9630286.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
     gene            complement(25506..>25807)
                     /locus_tag="J8S10_001701"
     CDS             complement(25506..>25807)
                     /locus_tag="J8S10_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAZ9630287.1"
                     /translation="TFDCGKEFSNWKAISNQHDIDIYFADPGTPSQRPLNENSNGILR
                     RNGLPKSMDFRKVNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
BASE COUNT         8542 a         4474 c         5439 g         7352 t
ORIGIN      
        1 gtatacttaa aaaagtagaa atatcagaac cttaaaagga tataatttga agaatataga
       61 acaaatgttc agtatttttt gatataataa aggagcaccg tatcatgtgt tgaaggagga
      121 aaagcatgtc tttacaattt attcttggaa acgggaaaaa agatcaccgt caagtcttga
      181 tcgacgaagc atccgcttgg ctcgaccagg atgcaagtaa ccaagtattt ttccttgttc
      241 ccaactacag caaattcgaa caggaacaag aaattttagc ggagatgcga agaagaagcg
      301 gaaaaaaaac tttcagcaca acaaacgttc aagtatttag tttttatcgt ctggcttggt
      361 atttgctgca acagacaact cttcttacag gaaatgaatt atcagaatca ggatctgcaa
      421 tgatcttgcg acagatttta gaaaaaaatg aggaagaatt aacaatcttt cgcggagaaa
      481 tcaataaaag agggtttatt cgtcaattac aagaactcta cagtgaattg cgtacaggaa
      541 atattcaacc agaagacctg atgcttttat ttggtgattc acctaatgca gaagaccagc
      601 aacttaaaat gaaagacttg aagctgattt tttcagctta tgacagcgaa ttgactcaac
      661 gtgcactaac aaatgaagat gcactatcta tactagcaaa ttatatgcag acacaagatt
      721 tcaacaacgt caaatttatt gtcagtggtt tttctcgaat caatggtcaa gagtatcaat
      781 tactgcaggc aatgatggaa aaggggcaat tggttgtcga tttattgctg gatcgtcctt
      841 atacagcgga tcttccagaa gtacttacgc tctttcatga gactggaaag ctttatttcc
      901 gtctttttca aagtgcaaga gaacggaaag tccctatatt agtggaccga tttgcaccag
      961 agcagactcg tccgacagag cttcaactgc tgcaaacaat gtgggaagag acatctagcc
     1021 aaaagaaagc ggcagtacac aaaatagggg gacaagagca tctccatttg tgggaagctg
     1081 aaaatccaac tgaagaagtc cgacaattag ctgttgaaat cagacgacta gtcagtgaag
     1141 aaaactaccg ttatcgtgat atccaagtgc tgacaaaaaa tatgtcttta tatggaaata
     1201 tccttcggcc gatctttcaa gaaatggcaa ttccttttta tatcgatgaa gaacaaatga
     1261 tggaaaatca tccgctgatc gaatggatca acagtctgtt cgctcttgac cgctattctt
     1321 atcggctaag tgatattatg cgttttttca aaactgaatt atttctgtcg acggaagcag
     1381 aaaccgaact tgatgaatgg aaacaagagc gagatgaatt caggaaaaaa ctggacatca
     1441 ctgaaaatgt agcacttgct tacaattatc aaggaactta ttggactcgt gaaaaagact
     1501 ggcagtttgt ggcgtatgat tttgaagcag aacagattga agacgtacag tatttggaag
     1561 aacagtcaaa tacgattaga cgattatttc agaaagctgt accagtattt ttgaaaaaaa
     1621 taaagaaaag caaaacagga caagaggccg caaatgtttt ttatcaattt ttgatccaaa
     1681 gtggcgtaca gcaacaatta ttgttttggc gtaatcagga agtagacaga ggaaacttag
     1741 aagcggcaag aaaccatgag cagacatggg gagcgctgat tgatctgttg gatgaatatg
     1801 tagtaattta tggtgaatcg gcttttgact ggtcactgtt ccaagaaatc attacaagtg
     1861 gtctagaaaa tctaagttat ggtaaaatcc ctaccgcaat cgaccaagtg cgaatcaatc
     1921 gtttggaatt agttcgacca aatcaagctg ccgtcacttt tgcattaggg ttgaatgatc
     1981 aagtgtttcc agaccgaaaa gagacaaaag gattgttgtc cagtgaagaa cgagaagtat
     2041 taaatcaggc cttgccagat ggacagtttt tattcgaccc atcaaaggaa agtatctctt
     2101 ttgagccttt ccaagcctat cttgtttttc tttccggaac agatcgatta tatcttagtt
     2161 atgcacaaag ctatgacaca gatggttcgc tgaagatgtc tccttatttg cgtagaatca
     2221 cagaatattt atctgttccc gtcgagagaa aagagcattt gacgatcgaa agcgacccta
     2281 attgttatgt agggacttac agaagcggaa tcaatacagt caataggatt tatcgattag
     2341 ctttagatga aaaaaaacct gtaccaaagc actggcaaaa gctcaaagaa ttagtactga
     2401 attcgtcatg gcgaaatttt gctttacaga tttttgaaag tcaggaacat ttaaatgttc
     2461 ctgtttcgat gccagaaaaa atggcggaag agctttatgg aaaagagatt tatacttcaa
     2521 tttcacgtat ggagaatttt tataattgtg aatacaaata cttcatgcaa tttggtttga
     2581 aattgaaaga acgaactgtt tatggtctaa ctccagcagc aactggtgat ttttatcatg
     2641 aatcattgga tcgtttcttc aagctactgt tttcaaacca attatcctta gtgaatatgt
     2701 ccgatgcgca gcgtagagac tttactgaaa aagtgctgca ggaagtattc ggagaacttc
     2761 ggtttgagat attggatagt tctgcaagaa tgaactatat ccgctaccag ttaggacaga
     2821 cgattcaaaa agtgacatgg gctttgcaaa aacagagcaa aaatacaggc atgcatcctc
     2881 ttcagacaga gattctattt ggtcagattg ctggagcaaa aggtatcaca ggtctggaat
     2941 taccgttgag taatggtgga aaactccatg ttcgagggaa aatcgatcga atcgatgtag
     3001 cttctgaaca agaagatact tggctaagcg tcgttgatta caaatctagc ggacgttcat
     3061 tcgatgtcac agaagcttat tatggcatgg ctatgcaatt attgacgtat ctggacgtag
     3121 cattgatgga tgcggtacgt ttgactggaa aggcggctgt taaaccagca ggatcatatt
     3181 atttacatgt tcataatcct gtattgacgg agacagatga tgtagagaag aatacattga
     3241 aaaaatttag ttatgatggc gtttttgtcg atgatcccgc tcttttagaa gtactagatc
     3301 attcactgga agcaaaagaa caatcactga tctatccagt gaaaaaaaat gcgaaagatg
     3361 aataccaaaa aggtagtttc agtaaagaca aatttttcac ggaagaagaa ctgcaactat
     3421 tcatggcgca taatcgggaa aatatgcggt tagctggaga tgcgattact tccggagaaa
     3481 tcaaactaaa tccagcttat aaagataaac agcggattgc ctgcgaattt tgtccattca
     3541 gaagcatctg tacgtttgat gtgatgctga aagaaaataa ttaccaccgt ctggagaaaa
     3601 tagataagga agaagcactg cgtagaatat tgaaaaggag tgaagaagag tgaatcaaat
     3661 tcctttaaaa ccgcaaaatg aacgattcac agatgatcag tggcaagcga tttttgatca
     3721 aggagataat ctattagtct ctgcgtctgc cggatcaggt aaaactacag tgcttgttcg
     3781 aagagtgatt gaaaaactaa aaatgggttt tgatatcgat gaattattga ttgtgacatt
     3841 tactgaagct gccgcaagag aaatgaaaga aagaattcaa gaggcattac aagaatccgt
     3901 caatagcgaa agtgaccctg tacgtagaca gcattttact aagcagttag ttttattgcc
     3961 cacagcgaat atctcaacct tacatgcttt ttgcctgaca gttattcgac gttattatta
     4021 cttaattgat attgatccag tctttcgcat gttaacagat gaaacagaaa cgatcttgat
     4081 gaaggaggat gtgtgggacg agctgagaga agcactttat gcagaaaatg atgaacgatt
     4141 tttccaatta acaatgaatt tttctaatga tcgttcagat gacggcttga cgaatctggt
     4201 gttttctctt tatgagtttg cccgtgccaa ccctgacccc caaaaatggc tagaacagtt
     4261 aagcgataat tatcgtttgc ctgaggggct agcgaaatct cgattatatc aaaaacaaat
     4321 ccgtccttta gttttggcag atatatacca atgtgtacag ttatatgaac agatgactca
     4381 gttagcacaa ggtgaaggat tagaaaaaat gcatgagcaa gtagctggag aacaacagca
     4441 gatcaagaat atctatgaag cgttctcgca agatcggtta gaagaagctt atgctggttt
     4501 ggaacaacta actttttcaa cttttaagag cagtcggaaa gcagaattga aagaaatttc
     4561 caatgaagtc aagggcatga gggataaagc aaaaaaactg attcagcaga taagtaaaag
     4621 ttattttcct gtttccccaa gccaaatgga agaattaacg gacaaagcac taccgttagt
     4681 cgaagaaatg acaaaagtca cgcaaagctt catggacggt ttcagtatgc gtaaacggga
     4741 aaaaggtgtg ctggatttca atgatctgga acatttagcg ttgcagattc tcacagaaaa
     4801 aacgaaagat gtatggctgc caagtgaagc ttcaaaacat tatcgaaaaa aattcaaaga
     4861 agtaatggta gatgaatatc aagacgtgaa ccaattacaa gaagccattt tatactggct
     4921 aagagaaccc gatgatacaa aaggaaatat gttcatggtt ggggatgtca aacaatccat
     4981 ctattctttc cgtttagcag atcctagttt atttatcggg aaatacgaga atttctcaaa
     5041 gaaagaaggc ggacgtcgaa tcgttttggc tgagaacttc cgctctagaa aagaagtcct
     5101 ttcttttacg aatcttattt ttgaacaact aatggatcca gcagtgggtc aaatcaatta
     5161 tgacgaagca gccaaactga tccaaggatt ttcagacttt ccagagaatg aacagtttga
     5221 gccggaaatc atgatctatg aaaaagaaca ggaagaatca gagattgaga ttccgacgga
     5281 tgatatactg gaagacaaaa cagaaggcga actttttatg acaggactaa aaattcgtca
     5341 attaattgat tcctccttta tgatttatga taaaaaatca aaaaaaagtc gtccgataga
     5401 gtacaaagac attgttctct tgacacctac aaagaagaac aacttaacga ttttagagat
     5461 tttcaaaaca ttggatattc cattagagat gaatgatgct caaaactatt ttcaagcgac
     5521 agaaattcgc acgatgatct cgctgctaca attaatcgat aatccctatc aagatattcc
     5581 gcttgcggct gtattgcgct caccgatcgt gggtctgatt gaaccagaat tagccagcat
     5641 tcgattagct aaccgtgcac atacttacta tgatgctgtg cttgcttatc aagcatcaaa
     5701 cgaagatgaa ttagcagcta agctggaaca ttttggcaag caactagagc attggcgaga
     5761 acttgctcgc cgttcttcga tcactgactt gttatgggat atctattatg agacgggata
     5821 tctagagtat gtggtcggtc tgccagcagg ggcacagaga caagccaatc tttatgcatt
     5881 ggttgatcgt gccaaagctt acgagcaaag ttctttcaga ggattatacc agttcgtgcg
     5941 tttcattgaa aaaatgcaag aaaaagataa agacttagca gaaccagtca tttcaataga
     6001 agataatgct gttcgcgtta tgacgatcca tgcaagtaaa ggcttggaat tcccagttgt
     6061 atttttgtta gatatgacaa aggagttcaa cttacaagac ttgcgcaatc ggtatgcttt
     6121 tgaagaaaaa cttggagcag gaattcgcta tatggatcct gaaacacgag tgttatatga
     6181 tacgttaccg tttcaagcca tcaaattggc aaagcaaaac aaattgttgt cggaagaaat
     6241 gcgtaaattg tatgtaggat tgactcgggc agaacaaaag cttttcattg tcggttccta
     6301 taaaaataaa gagcaaatga tccaaacgtg gtctgaagca gctgatcatg aggagttagt
     6361 ttttgatcct gcgctacgtt tgaagggcag aagcagcttg atgaattgga ttggttacgg
     6421 attgatccgt catcctgaaa tgcagaaata cttagaggaa gaaatttcga cttctcttct
     6481 tcaacattca aatgcacagt tttctatttc atggatgaat cagcaatcga tcattgaaca
     6541 aagacagttg cttgctgaaa aagaactggt taacttagat cagcagatga aagaagatga
     6601 aactttatta gcagattcgt tacaaaaacg tctggcatat gaatatcctt atcaagcttc
     6661 ttcacaaacc acaagttatc aatctgtatc tgaaatcaaa cgattattcg aagatccaga
     6721 tgatacacaa gaatcacgtt tgactctgga aagcagtcag aacaaagcag catcccgtca
     6781 atttcgttat acgcaagaac aactagcaga accaaaattt ttgcaaaaag atcggcaagt
     6841 gtcagcagct gctgttggaa ctgctacgca tgctttgtta caattactgc cattagagat
     6901 gccaactaca gagagtatcc atcaaaaatt acaggaattg gtaaggaaac ggttagtaga
     6961 cgaaaaagtc gcgaaaaaag tagatgtttc ttctattata tggttctttc aaacagaact
     7021 tggtcaacag ctgattgcca acaaagaaaa cgtaaaacga gaacaacctt tttccatgct
     7081 gcttcctgct gacgaagtat ttcaagacta tccaaatcaa gaagatgaac tattaatcca
     7141 cggaatcgtc gatggatacc tagaagaaaa agatcatctc aatatctatg attttaaaac
     7201 agattttatt ttacatccgg atgatccagc agaaatagat gcaatcgtcc aaaaatatca
     7261 aggacagcta agactttacc aacaagcaat gtcagaagct ttgaataagc cagtagaaaa
     7321 tgttttccta attttgcttc gagtgaaaca aattataaac attaacaaat aattataatt
     7381 gagcaaactt gacttatgtt ttgtaaggat tatgctatac tctgggaaga ggtgagtatg
     7441 atggagctaa cacagacaga attcgtttta tgccctaaat ttgaaaaaac attctctatt
     7501 ttaggaaaaa aatggaacgg attgattatc gatgtactac tcgaaaacgg tccgcaacgc
     7561 tttgttgagc ttgcggcaaa aatcccgatg gtcagtgatc gagtattagt cgaacgcttg
     7621 aaggaattag aaaaagaagg aatagtcact cgaaactttg cctgtagcga aaagagccgt
     7681 tcagaatatc tcttgactga aaaaggagca gacttgcaaa aagcgatgcg tcaaatacaa
     7741 gtttggagcg aaaaatggat cacagaggaa gaatgcggtt gattttgtaa aaaaaatctt
     7801 gtaaactata gtccatacga ataagtaaag aacgatgacg aaaaagagta gtttggctaa
     7861 accagttcag ggagatctgt cgcagactga aagcagatcc tgtgtttgaa aaatgaagtt
     7921 cactttccga gttcgtctga taaaatcaga ccggcaattg tcgttaacga agtaagagtg
     7981 cggtgtaagt catttatccg caaattagga tggtaacgcg aagacctcgt tccttaacag
     8041 gaatgaggtc tttttgtttt gtatttggaa tttaaaggag gaacaagcac atgtctctac
     8101 aagcacaatt agagagcttg aaagaagcaa cgctcgtcaa aatcacagcg gcacaagatt
     8161 taaatgaatt aaatcaaata cgtgttgaaa cgttaggaaa aaaaggaccg atcacagaag
     8221 tattacgtgg gatgaaagat ctaagtccag aagagcgacc aaaagtcgga agtttcgcaa
     8281 atgagatccg agatcttttg acagaagaga tcgagcgaaa aaaacaagta ttagaagaag
     8341 aagcgttaaa tgcagctttg gcaaaagaaa caatagacgt gacactacct ggtagaaaag
     8401 taaaacatgg tacacgtcat atcgtgacac aaatcatgga agaaattgaa gatatttttg
     8461 tgggtatggg ctatcagatc gtagaaggat atgaagtaga atctgatcat tacaatttcg
     8521 aacggatgaa tctgccaaaa gatcatccag caagggacat gcaagatact ttctatattt
     8581 cagacgagat attgattcgg acacatactt caccagtcca agcacggaca atggaaaaac
     8641 atgatttctc taagggtgct ctacgaatga tctcgccagg gaaagtcttc cgcagagata
     8701 cagatgatgc gacccacagt catcagttcc atcaaattga agggctagtt gttgataaaa
     8761 acatcacaat gggcgacctt aaaggaacat tagaagtcgt aatgaaaaaa atgtttgggg
     8821 aagatcgtga aattcgtttg cgtccaagtt atttcccatt tacggaacca tcagtagaag
     8881 tagatgtcag ctgtttcaaa tgtggtggtg ccggttgtaa cgtatgtaaa tacactggat
     8941 ggatcgaaat tttaggagct ggcatggtac acccgaatgt gttgaagatg tcaggaatcg
     9001 atccagaaga atattcaggc tttgctttcg gccttggacc agaccgcgta gctatgttgc
     9061 ggtatggagt gaatgatatc cgtaatttct atcaaaatga cttacgtttc ttaagtcagt
     9121 tcaaggggga gtaagaaaat gttagtttca tataaatggc tcaatcgtta tgtagattta
     9181 tcgaatgtaa caccaaaaga attagcggat aagatgtctg tgacaggaat cgaagtagag
     9241 ggagtaacgg ttccagaaga aggcttgaaa aaaatcgttg tcggtgaagt caaggaatgc
     9301 gtaccacatc cagattctga tcacctttct atttgtcaag tcgatattgg cgaagacgaa
     9361 ctgtctcaaa tcgtttgtgg agcgcctaat gtgaaggttg gaatcaaagt gattgttgca
     9421 cttcctaact cacgtatcgc tggtaatgta aaaatcaaaa aaggaaaaat gcgtggccaa
     9481 gtatcaaatg gcatgatttg ctcattacaa gaaattggct attcagatag tgttataccg
     9541 aaagaatacg ctgaaggtat ctattatatg ccacaagaag ctgtaaatgg cgatccagtt
     9601 tttccttatt tggatatgga tgattcgatt attgaattat ctatcacacc gaatcgtgcg
     9661 gatgcattgt caatgcgtgg cgtagcttat gaagttgggg caatttatcg tcagactcct
     9721 acattcgatg acgaaaagct ggtagaatcc tcacgtcctg ctagcgataa aattcaagtg
     9781 gaagttgaag ataaagaagc agttcctgct tatcaaatca gaatcattga aggagtaaga
     9841 atccagccaa gtcctcaatg gctgcaaaat cttttgatga acgaaggcat tcgtccaatc
     9901 aacaatgtag tagatgtgac gaactatatt ttgcttttat tcggacaacc actacatgca
     9961 tttgactacg acaaattgaa atcaaaagag atctttgtcc gccgtgcaaa agaaaatgaa
    10021 acattagtaa cactagatgg agaatctcgg gaattgacaa ctgacaatct cgtcattact
    10081 aacggcaaag aaccagttgc tttagctggt gtcatgggag ggttagactc agagatcacg
    10141 aatgaaacaa caacagttgc actagaatct gctttatttg atccaatttc gattcgtcgt
    10201 acagcaaaac aatttaattt gcgtagtgaa tcctctgcac gttttgaaaa aggaatcaac
    10261 catgcgactg ttggagaagc cagtgaggtt gctgcagcaa tgatcgtttc tcttgcgggt
    10321 ggggaagttc tacaaggcgc ggtcaaaggc tcagagatca aagcagaaga cgtatcagtg
    10381 aagatttcac ttgaacgcat caatcaatat ttaggaacat ctcttgtcgt taaagaagta
    10441 aatgagattt ttgaagcact tggatttagc tatgaagaaa aggagtatgt ttattccgta
    10501 gtagtaccac caagacgctg ggatatccaa atcgaagcag atattatcga agaagttgct
    10561 cgtatttatg gatacgacca gttgccatct acacttccaa gtggagaaac ggttgctgga
    10621 agcttgtcaa aagaacaaga aactactcgt aaaattcgta caatctttga aggaagcgga
    10681 ttgagcgaag caatcagtta tgcattgaca acagaagaaa aatcaagaca gtttgttata
    10741 aatgaaagta atattacacg tttggactgg ccaatgagcg aagaacgttc tgtattacga
    10801 atgaatttga tcagcggact attagatgat atcagttata acactgcccg aaaaaataca
    10861 gagattgctt tatatgaaat tggtcgggtg ttcttccaag aaaatgatcc acgtacacat
    10921 ctgccgcaag aagtaaaaca tgcagcaatc gctatttctg gtatttggga agaaaaagat
    10981 tggcagacga aagctcaaaa tgtagacttt ttcaccatca agggtctttt agaaaactta
    11041 tttgaacaac taggcatcac tgaagatgtc cattatcaaa cagtgacaga aatgaaggaa
    11101 atgcatcctg gaagaactgc tgcgatttac cttggcgaaa aatttattgg ttttgtcggt
    11161 caagtgcatc caacgattac aaaaagttat gatattccag aaacatatgt tgctgagttt
    11221 gatttatctg ctatagtgga agctgctcaa aaagggatcg ttttcgaagc agtgacaaaa
    11281 ttcccagcag tcagccggga catcgctttg cttgtaaaag aaactgtgac aaatcaggaa
    11341 ttaacagaag ttatccgttc tgctgccgga agatttttaa cagatatcca attatttgat
    11401 gtctatcaag gagaaaacat tgaaaaagga cataaatcca tggcgtatag cctgacattc
    11461 gtcaacccag aagcaacatt gacagatgaa gaaatcaata aagcaatgga aaaagtcgaa
    11521 aaagcgttgg tagaaaacct agaggcaagt attcgctaag aaggaaaata tagtaagtaa
    11581 cgatcaagta gcttttgaag accatacatt tgaaaaaaag atgtgacaca acttcgtcac
    11641 atctcttttt ttgattttaa aaaaggaata gcacagagac gagataaaaa aacaggcctt
    11701 tacagcctgc ttttttagag taaatgaatt aatggaagta attgattccc attgctgatt
    11761 ttacttcaga aagtgtttgt gcagctactt tagcagcttc ttcactacct ttacgtaaga
    11821 tttccataac agctgaagga tctttttcca attcttctcg gcgcgcacgg atcggtgcaa
    11881 attcagcttc caatacatca atgaggtatc gtttgatctt tacatcacca agtccgccgc
    11941 ggcggtaatg agctttcatt tcttcaattg cttctttatc tgttccgaat acatccaagt
    12001 aggtgaagac catattccct tctacttgtc caggatcttg tacatggatg tggtttggat
    12061 cagtatacat actcatgact tttttctgta agacatcggc aggatcggag atataaatac
    12121 cgtttcctaa cgatttactc attttgccat ttccatcgat tccaggtaat ctacccattc
    12181 cttttggtgg gaatacgcct tttggttcca ccaagacttc accatatgta tgattgaagc
    12241 tttgtacgat ttcctgtgtc tgctctagca ttggtttttg atcctcacca acaggtacaa
    12301 gattcgcttt gaatgcagtg atatctgctg cttgagaaac aggatagata aagaatcctg
    12361 taggcacgct ttcaccgaat tttttttgtt cgatttctgt tttgacagtc ggattgcgcc
    12421 gaacgcgtcc tacgctgact aagttcaaat aatacatggt taattcagct aattccggaa
    12481 tttgtgattg gataaataaa gtagattttg caggatctaa tcccacggct aaatagtcta
    12541 aagcaacttg caagacattt gatgaaacct tctcaggatt tttagcatta tctgtcagtg
    12601 cttgcatgtc agcaatcatg acaaacagtt ggttgtcttc atctgcctgc atagccactc
    12661 gggtttttag agaaccgacg taatgcccta aatgcagctt cccagttggt cgatctcccg
    12721 ttaaaataat atttttcaaa aaagacacct ctttacgatt tgtaagtctg agcacttaat
    12781 atcttaccgt ttttcctgaa aagaaacaac agttcctaag gaaaaaacaa ggaaagagga
    12841 taaaataact aatagattag aaatggaaga aatatttatg ggagaataaa cgttctaaga
    12901 aactttacaa attactaaac tatcagatat aatgtatttt attatacatc tttaaaagaa
    12961 atcttactaa ataataatgg gagtgtaatt ctatggcaat gattaaattt gatcacgtgg
    13021 ataaatatta tggcaagttc cacgcattaa aaaatatcaa tctcgaattc gagaaaggag
    13081 aagttgtcgt tgtcattggt ccttctggtt caggaaagag cacgatgctt cgctgtatca
    13141 atggattaga gacgatctct tcaggtaagc tgctgattaa tgatactgac ttgcatgata
    13201 aaaagacaaa actgacagaa gtccgaaaaa acatcggcat ggttttccaa catttcaatt
    13261 tgtacccaaa taaaactgtt ctggaaaaca tcaaattagc accaatcaaa gtgttgaagc
    13321 aagaccaggc aactgcagtc aaaaacgcgg agaaattttt gaaaactgtc aatatgttag
    13381 ataagaaaga ttcttatcct tccatgttat ccgggggaca acagcaacgg gtggcaatcg
    13441 ccagaggttt agcgatgaat cctgagatgc tgctgtttga tgaacctact tctgctttgg
    13501 atccggaaat gattggtgat gtattagacg ttatgaaaaa attggctcat gacggtatgt
    13561 caatgattgt cgtgacacat gaaatgggct ttgccaaaga agtggcggat cgtgttatct
    13621 tcatggctga tggagaagta ttggaagaca gcagaaatgt gagagacttt ttcgaaaatc
    13681 caaatgaagt ccgagcacag caatttatca gtaaagttat caatcattga taggaggaaa
    13741 aagatgcgca ggttaaaaaa aatacgcctg attttccttt taggcattgc ttttcttgca
    13801 ctagccggat gtaaaggaaa tgggttggca aatgaagata ttttagagcg aagcaaatct
    13861 accaatgaaa tcatctgggg tgtcaagtat gatactcgat tatttggaat gatggatatt
    13921 gagagcagaa ctgtacaagg atttgatgta gatattgcaa aagcaatcac taaaaagatc
    13981 cttggtgaca atggaaaaac agaatttgtt gaagtcactt ctaaaactcg gattccatta
    14041 ttgaaaaacg gaaatatcga tgcaattatt gcaacgatga cgatcacaga tgaacgaaaa
    14101 aaacaggttg acttttcaga tgtctatttc gatgctggcc aagctttgtt ggtaaagaaa
    14161 ggaagccaaa tcaaaagtgt agatgatttg aatgcttcta caacggttct agcagtcaaa
    14221 ggttctacat cggctgcgaa tatccgacag catgcaccag atgcaaaaat tttagaatta
    14281 gaaaactatg cagaagcatt tactgcttta caatctggtc agggagacgc gatgactacg
    14341 gataatgcga ttttgttagg gattgcagat gaaaatccag agtatgagtt agttggtgga
    14401 acgtttacta atgagcctta cgggattgcg atcaacaaag ggcaagaaaa cttcttgaaa
    14461 gctgttaacc aagcgctaga ggaaatgcat gcagatggca catacgataa aatctatcaa
    14521 aaatggtttc caaatgaaac tgaaggaaaa gtagagtaag ggggagaggc aatgagcgaa
    14581 ttgatacaaa cttatggacc aatctttgtc gacgggttca agatcacatt gttttcgagt
    14641 gtcttagcac ttgtgtttag tttgattatc ggaacgttaa tggcaatctt ccaattatca
    14701 aagaataaag tagtgagcgc cttagcaaag gcatatgtag aattttttag aaacattcca
    14761 ttattaatca tcgtgatgtt tttttatgtt gtcgtaccga tttattggtt taatctagat
    14821 ggattccaag caggtacgat tggattaacg atctatacat ctgcttttat tgctgaaaca
    14881 gtacgttcag ggattcaaac cgtaccaaaa ggtcaaacag aagcaggact atcttctggt
    14941 tttacctatt cagaaatcat gcgttatatt gttttaccgc aagcattcaa aatcgttatc
    15001 ccgccattag gcaaccaatt tatcaacctc gtaaaaaact catctatttt agcaatcgta
    15061 gctggtttag atttgatgta tcaaggagac ttgatcgcta gtgaaacatt caataccttc
    15121 gatacgtata tcatcgttgg gttattttac ttagttatca cgctaccgtt atcttactta
    15181 atggtttatc ttgagaaaaa atgggcggtt cgttcataga aggaggggaa atacatggat
    15241 tttagcggcg ctttttcatg gatgaatatc cgttttttat tggaaggatt aaaggttact
    15301 gttgaagttt cattgttttc gatcattttt agtttcttga tcggtggtct gacaggtgtg
    15361 attcgttttg cgaatatccc tttcttttcc aaaatccttg gtgtagtgat tgatattata
    15421 cggaatcttc cattattatt gatcattttc ttcacttact ttgccttacc tcaaatcggc
    15481 attcagatga acatcttctg gtccgctgtc gcagcattaa cgatttttga gtcagctatg
    15541 ttgtcggaaa ttttccgagc tggactcaat gctgttccaa aaggacagat ggaagcagga
    15601 ttatcaacgg gactgactta tgtagaatcg atgcgaacga tcgtgttacc gcaagcattt
    15661 aaatcaatga tcccggcaat tgtgagccaa ttgatttcac tgatcaaaga tacttcatta
    15721 gcagtaatca tttctttacc tgaactttct catcaggcac gtattattta tggacagaac
    15781 accaattatg tgcttccgat gttcatcatc atgacactta tgtacttcgt ggtatgttac
    15841 gcgctttctc tgctttccgg ttacttggaa aagagacggt acagttatta atagatgatt
    15901 cttttagcgg ttgtggcaaa ctaaagtcac aaccgctttt cctctttcca ttcgaaaaaa
    15961 agagatttcg attgttttaa gcaagtaaga gcacttgaaa attcacgcta aaaagtacac
    16021 aatagggagg atagaattta ttgaaaaaaa ggatgatacg attgacagat aatcgcccta
    16081 tcggatttat tgattcaggt gtcggcggct tgactgtagt aaaagaagcc ctgaaacaat
    16141 taccgaatga aaatatttta tttgtaggag acacagcacg ctgcccatat ggccctagac
    16201 ccgcggaaca ggtaatccag tatacttggg aaatgacgga ttatctggtg gagcaaggaa
    16261 tcaagatgct ggtgatcgcc tgcaataccg caactgcggt ggctttagaa gaaatcaaag
    16321 ctgctctttc tattccagtc atcggtgtga tccttcccgg tactagagcg gcagtaaaaa
    16381 aaacacaaaa taaacaagtt ggcattatcg gtacgattgg tacggtaaaa agtcaagctt
    16441 atgaaaaagc actgaaagag aaagtaccag aattgactgt gacaagtctt gcttgtccca
    16501 aatttgtttc agttgtcgaa agtaatgaat accattcatc ggtggcgaaa aaaattgtgg
    16561 cagaaacatt agctccttta accactaaaa aaatcgatac attgattttg ggatgcaccc
    16621 attatccatt attacgcccc atcattcaaa atgtaatggg agaaaatgtt caactgatcg
    16681 attctggagc agaaacagta ggtgaagtat ctatgctgtt agattatttc aatttgagca
    16741 attcaccgca aaatggtcgg acattatgcc agttttatac aactggctct gccaaacttt
    16801 tcgaggaaat agctgaagac tggcttggaa tcggacactt aaatgtagaa catatcgaat
    16861 tgggaggaaa ataaggatgc gtcatgacgg gagaaaagcc caagagcttc gcaaactgga
    16921 gcttcaaaca aatgttttca aatatccaga aggatcggta gtgatccgtt ttggtgatac
    16981 aacagttatt tgttctgcaa caatagaaaa ttctgttccc ccttttttga gagaaacagg
    17041 aacaggatgg gtgacagcag aatatagtat gctgcctcga gcaacgagta cgagaaatcg
    17101 tagagaaagc agcaaaggga aactttctgg tagaacaatg gaaatccagc gtcttattgg
    17161 tcgttccttg cgtgcagtag tagacttgga aaaattagga gaacgtagta tcatcgtaga
    17221 ctgcgatgtg atccaagcgg atggcggtac tagaacagca agtatcactg gggcatttgt
    17281 ggcattgaaa ttagccattg aaaaactttt aagagaaaaa gaattgtcag aagatccaat
    17341 aaaagaacat cttgctgcag ttagcgtagg aatcttacca gatgggactt gcgtcacaga
    17401 tttggattac caagaagatt ccgcagcact tgtagacatg aatcttgtaa tgacagaatc
    17461 tggaaaattc gtggagattc aaggaactgg agaagaagca acgtttgatg gtgaacagtt
    17521 gaatgaaatg ctcttttttg gaaaaaacgc gattgaagat ttgatcaaag agcaaaaaca
    17581 tgctttgcta acagagtttg ctcaaaatga tgagcggata gaagaaacaa aaacaatcat
    17641 cattgcgaca agaaatccag gaaaagcaga agagtttcga aatatgttca aagaagcggg
    17701 atatcatgta aaaacattac ttgactatcc tgaattgcca gatgtggaag aaactggcag
    17761 cacatttgaa gaaaatgccc gattaaaagc agaaacgatt gcacaattgc ttgatcagcc
    17821 agtcttagca gatgattcag gtttgaaagt ggatgcttta ggcggtatgc caggaatcta
    17881 ttctgcacgt tttgcagggg aacaaaaaag tgatgcgggg aataacgcca aattattata
    17941 tgaattgaca gatgtgccgg atgaaaaaag aacagcacaa ttccattgta cgttagtatt
    18001 cgcggcaccc aaaaaagaca gccttgtagt agaagcggaa tggcccggtc gagtagcccg
    18061 tataccatct ggcgaaaatg gctttgggta tgatccttta tttatcccag aaggtaagaa
    18121 acaaacagca gcagaattat cgagcgaaga aaaaaacaag atcagtcatc gggctcaagc
    18181 aatgaaaaaa ttgagtgccg agtggaaaca atggctggaa ggagagagat agatgcggta
    18241 tttagtagta agtgataatc atggagacag agatatcctc gttgacttag tagatcgtta
    18301 tcgttctgaa gtggatatct ttttccattg tggtgattcg gaattagaag cttctgaccc
    18361 attatgggat acattccaag tggttcaagg taattgtgat tatggaccag gattcgaaca
    18421 gaaaaaagtg atccaaactg gtcaggatac agtattcatg actcacggtc atttatcgaa
    18481 tgtccgattt ggtttgacac agttagcaat cgaagctcga gctgcaactg ccgatatggt
    18541 gttttttggt catacccatc aaataggctg tgagatggat cagaaaatcc tgtttttgaa
    18601 tcctggtagc atttctcagc ctagaggccc gatccaaatc ccatcatatg ctcttatcga
    18661 aagtttagat gaccaaattt ctgttcaata ctataaccgt gcccatcagg cagttgaaga
    18721 gttggccttt tctttttcga gagagcgctg aataaaaaaa ctctaatttt taataaaaat
    18781 aagctttatt ttatgaattt tgcatccggt ttcggtaaaa tagtagtgtt gaatgaaata
    18841 gaaatggagg ccatcagatg attggaccta tagtaagaga aatgctgctg gaaaatcagg
    18901 aaacgttttt gattcctgca gaaaatgtgg caaatgttat gtatcatcat ccattgtccc
    18961 atggtttact tgtgttatcg aaggtcggtt attccaaaat tcctgtatta ggaaaagatg
    19021 atcactttgt aggactagta agtttatcag atgtggtcaa taaaatgatt gacttgcaaa
    19081 caatcagcat ggacccgtta gaaggactaa cggttgctga tgtgacagaa acagatgttc
    19141 cgacaattga tgaaaattgg gaactagaag aagtactcca tttgttagtc gattcgcctt
    19201 ttttaccggt tgtcacagaa gatcggattt tcaaaggaat cattacaaga aaagagctgc
    19261 ttaaagccgt aaacttcatg gtgcatgaat tagaacgtcg taatatattg tctccgaaaa
    19321 tcgaagaatt aaaagaacaa atcgatatcg tgagctaaag aacgagaaac taaaagataa
    19381 tcaaaaaata agtagaaaaa acagcgtacc agttttgact ttatcttgaa aaagaggctg
    19441 ggacaaaagc gtttaactcc aagaaataag aaggaattca cgaaaattgc ttttcaaatt
    19501 tttgtgaatt tcagcttatt tccgaaggag ttgcttctgc ttccgccgtt tatacgtgtt
    19561 tagagcgtgg gacaaaagtg ttctttactt ttgtcccacg ctctttttag tgagattcgt
    19621 tgcatcgttt gtccaaatta ttttccgaca gcaattggac tgttcggaat cgtgaaacca
    19681 gaagctgtca attctttgac ataggagctc aagaactctt cttttaaggc atattgtttt
    19741 ccgttcaatg cgtagcagac cgtacgaatc gcaaaattgc tgtttccaag atccactaat
    19801 ccaaagatag aaggttcagt ttggagctct tcttggtatt tttcagctaa tgtacgattt
    19861 actcgatcaa tgatctcata gattttgtca tatccttctt caggaacaat ccgaatatct
    19921 aaaagtactt gcatatttgc acgagagaga ttgctgatcg tggtgatgtt tcgattcggg
    19981 atgaaatgga cagtaccatc cgttgctttc agctgaaggg tacggatacc aacagatacg
    20041 acggttcctt caatcgttaa gtttgctagc ttgatgtagt ccccaacatc catctgttgt
    20101 tccatgataa taaaaaatcc ggtaataaca tcactcatga acccttgggc accaagaccg
    20161 attgccacac ctgcaattcc ggcaccagcc aaaagtgatc cgatcggcac accgatagca
    20221 gataaaattg catagataaa aaagaaacca agggtataat gaaaaatagt atttaaaaga
    20281 ctatgtaaag tctttaagcg gctctcgttt agaatggctt ttttagaata ctgattaaaa
    20341 gacttatcaa tcagatattt tcccacacgg tgaagaatcc aaaaaaggac gatcaaaaaa
    20401 atcagatata aacttttttg gataaaggca gccaaaatgg cgtcccaatc aatcccgtcc
    20461 caaaaccgct gaaacgcatt tactttgctg acagcttgat ctgtcaatgt ctcgccagaa
    20521 gagtctgtcg taccggcagt tgctaataat gaaaacataa aatcctcttt tctaaaattt
    20581 gattctttct gtattgtacc aagaagtttt caaaaaagga aatagcaaaa ataactataa
    20641 tgaaggaaaa aagctgaaaa taaaatgaca aataatatgg ataatgataa aatgtggaga
    20701 aaataacgaa ggtggtaagt atatgcaaat cgattggaac aatctaggtt tttcttatat
    20761 caaaactcct tggcgtttta ttgccaaatg gaaagacgga caatgggaag aaggagaatt
    20821 gacagaagat aattacctga cgattcatga aggctctcca gcgcttcatt atggtcagca
    20881 atgttttgaa ggtctaaaag cttatcgtcg aaaagacggc aaggtcaatc tctttcgacc
    20941 tgaacaaaat agtcgacgga tgaatcaaag tgctagacga ttgctgatgc caatggtccc
    21001 tgaaaagatg ttcgttgatg ctgtcaagca agtggtaaaa gcaaatgaag attttgtgcc
    21061 gccctatgga acaggcgcta cattatactt gcgcccttta ctgattgggg tcggtgaaaa
    21121 cattggtgtc catccagctc cagaatattt atttgtcgtc ttctgtacgc cagtaggagc
    21181 gtatttcaaa ggtggactaa aaccaacgaa ttttattgta tctgattacg atcgtgctgc
    21241 tcctaagggg actggtgcag caaaagtcgg cggaaattac gcagcgagtt tacttccagg
    21301 aacagaagca aaagaactgg attactcaga ttgtgtttat cttgatccag ccacacatac
    21361 gaaaatcgaa gaagtaggtg cagcaaattt ctttggaatt acaaaagacg gaaaattcat
    21421 cactccgcaa tcgccctcta tcttaccaag tatcacgaaa tattccttgt tgcagttagc
    21481 tgaagaacga ctaggactgc aagcaattga aggagatatt ttcattgatg atctagatca
    21541 atttgcagaa gctggtgcat gtggtacagc ggctgttatt tctccaatcg gtgggattta
    21601 tcacaataac aatcttcatg tattttatag tgaaacggaa gtaggaccag taacaaaacg
    21661 gttgtatgat gaattgacag gtattcaatt tggagacata gaagcaccag aaggctggat
    21721 tgaagtcgtg gaataatttc aaagtaatga gttgaaaaaa acgtaaaaag aaaaaatcag
    21781 gaagagactt taaaaagttt tttcctgatt tttatatgtt ttactttaaa gaatgcaaca
    21841 aaagtttatg aaagatggac acctttgtca acgtagataa tatcaccgat gattccgctg
    21901 gaaagtgggc tgattaagaa agcacaagca ttaccgactt cttcgatcgt cacaccttgc
    21961 tgatcaggcg tacgagattc agataactgg atcagttttt gatagtcttt aacacctgtg
    22021 acagctaatg ttttgattgc cccagctgag attccattga cccgaattcc tttaggcgag
    22081 aactcagctg ccaaataacg gatagcagct tcaagagaag ctttcgcaat acccatcatg
    22141 ttataattcg ggattgcgcg ttctgaacct agataagtca tgctaacgat cccgctgttt
    22201 ggtgcaagaa acggttgtgc gtattttgat acagcaatta aagagtagct gctgatatct
    22261 tgagctaatt gatagccgtc tctggaaata tcagacacat ttccggacaa ttcttctttg
    22321 ttggcgtaag caactgcatg gacaaggccg tggatctccc cagcatattc accgatggca
    22381 ttcattgctt tttcgatgct ttcgtcgcta gaaacatcac attctacagt gaatgcttct
    22441 tcgccgacca atttgactaa tgattttttc attcgttcat tttggtaagt atagataatt
    22501 tctgcccctt gtttcaacat tgcttcagca caaccccaag caatgctttt tttgttagcg
    22561 acgcccataa tgacgatttt ttttccttct agaaatgaca taatgactct cctttgtttc
    22621 tgataaaaat ttgatagtcg taaaaaaata gagaataata gctaaaataa cttcttgatt
    22681 tcttaattat tagtcaaaat gttttgattg tcaaactatt ttttcttaaa ttaaaaaaag
    22741 attgctaaat atttaggaat atgatacttt gatagtcaaa gtaatgaaaa tggcaattgc
    22801 ctgaaagaag gagtttaatt atgtcttacg tattatctgc tactgaagta atggaattga
    22861 ttcctaatcg ttatcctatt tgttatattg attatgtaga tactttagaa ccaggaaaaa
    22921 agatcgttgc gacaaaaaat gtaacaatca atgaagattt tttccaaggt cactttcctg
    22981 acaatccagt gatgccgggt gcgttgattc tagaaacact ggcacaagca ggttcgatac
    23041 ttatcctaaa atcagaagag tttctaggaa aaagagctta tatcggtggg atcaataagg
    23101 ccaaattccg tcaaaaagtt gttccaggag atgtgctgaa atgtcatttt gaaatcacca
    23161 aaatgaaggg atcagtcggt acagcgttat ctgcagcata tgtagatgat aaaaaagtct
    23221 gtgagtgcga gttcacgttc atcgtcaacc aaaatgcttg actataaaac ctgatatagc
    23281 aaaacaaaag gaagcttact tgctttttat gtaaaaagaa gacgcctgaa tcctagcata
    23341 cgttgtcatc tatgcaggat tcagacgtta tttttttatt tttgttttgc ttcttgcagt
    23401 atattgattt tatcgatttt tacttcttct tttggtttgt ctgaactatc tgtttcgata
    23461 tttgcaatag catccacgac atccattcct tcaatcactt ggccgaagac agtataatgg
    23521 ccatctagtg aaggataacc gccgttttta taagcgtcga tgattgcttg aggatagtcg
    23581 tcttttaaaa gaccatcatg catatcatct gtattttgaa cgataaagaa ctggctgccg
    23641 ttactgttag gatcttgtga gcgagccata gataacgcac ctcttatatt ataaaggtgg
    23701 ttgttgatct ctgtttcaaa tccttctccc caaatgcttt cccctccagt gccatcgcct
    23761 ttaggatcgc caccttggat catgaaatct ttgatgacgc gatggaaagt cagtccgttg
    23821 tagtaaccgt cttttgcatg tgtcataaag ttttcaaccg cttttggtgc gtgttcggga
    23881 aataatttga ttttgattgt gcctttattc gtcaccattt cgaccagatc ttcattttcg
    23941 gcgacatctt tcgtcaattg tggtaattcc aatgcgttca aatcgacgct actggcagtc
    24001 gtgctttccg cagtagatgt actttttgaa ctttctgtag acgaactaga agaagtcgtg
    24061 ttgtttgcag aacaaccagc agcaaacagc aatgctgctg ctaaactaat acttaaaata
    24121 actttatttt tcttcataac tgttcctttc caatttacta ttttgttatc tttaatgata
    24181 acaaaataga gggaaaatac ctacttaaat tattggaatt tatcatttat tttaaaagaa
    24241 aaagaaaagg tgtagaccat ttactttgtg tttgctataa tgtaagtgga tacaaaaacg
    24301 aaaagatgca ggaggaaatg gtaatatggg aaaattagga atctcgattt atccagaacg
    24361 gtcaacattt gaaaaggaca aagcgtactt ggatttagct cataagtatg ggtataaacg
    24421 ggtttttacc agtttgctgc agatcaatga tgataaagaa aaagttcttt cagaatttaa
    24481 agaagtagtt gattacgcga atagcctagg catggaagta atggttgata tcaatccagc
    24541 gttatttgaa cagttggaga tttcttacga tgacttatct tttttccata agatgggtgc
    24601 ctacggggtc cgcttagata tcggattcac aggagcagaa gaagcaaaaa tgacgcgcaa
    24661 tccttttggt atcaaaatcg agatcaatat gagttcgggc acgaattacg ttgacaacat
    24721 catgagttat tcgccaaaca cggataattt attaggttct cataattttt atcctcatcg
    24781 atactctggt ttaggatacg aacactttgt tttttgttca gaaaaattca gaaaatataa
    24841 tttgaatacg atggcattcg tcaattcgca atctgctgag tttggccctt ggcctacgca
    24901 agatggcttg tgcacgctgg aagaccaccg agatcttgaa attgcgacac aagtgaagca
    24961 tttaatcctt acaggattga ttgatgatat ttctattgga aatgcgtacg caagtgaaga
    25021 agaattgaaa gaaatggcag aagcatttaa cgcggattat ccaacattga aagtagatac
    25081 ggaagaaggt attacagaaa acgaacgaat ctgcttgttt gataaccttc atagttatcg
    25141 aggggatcgc tcagaatata tccttcgttc aacgatgact cgtgtatact acaaagataa
    25201 agatttcccg cctcataata cgcgagatat gcatcatggg gatgtactga ttgacaatga
    25261 agggtacggt caatacaaag gagaaacaca aatcgccttg aaggatatga aaaacgacgg
    25321 acgtgtcaat gttgtaggaa gaatctccga tgacgaatta ttcctccttg actttttgaa
    25381 accatggtca agctttaaat taattgaaaa taaaaaatag ataattagtt attgcagaaa
    25441 taatccgcta gaaatagcca gttatttctg cttttttatt ttgttttttt ataggttatg
    25501 atttgtcaaa ttaagctaga ataaaatgct tcttgtacat agctcaaaaa tatttcgatt
    25561 ggtgttctgt aattcaatga ttttcttgga atatgattac gttgattgct gacactggaa
    25621 ataaatgtct gattcacttt tctaaaatcc attgatttcg gcagtccatt acgacgcaga
    25681 atcccgttag aattctcgtt taatgggcgt tgagaaggtg ttccagggtc cgcaaaatat
    25741 atatcaatat catgttggtt actaatggct ttccagttag aaaattcttt tccacagtca
    25801 aacgtaa
//
LOCUS       DADQDV010000040        24882 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.040, whole genome shotgun sequence.
ACCESSION   DADQDV010000040 DADQDV010000000
VERSION     DADQDV010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 24882)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24882)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24882
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.040"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(43..2187)
                     /locus_tag="J8S10_001702"
     CDS             complement(43..2187)
                     /locus_tag="J8S10_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAZ9630288.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(2544..3917)
                     /locus_tag="J8S10_001703"
     CDS             complement(2544..3917)
                     /locus_tag="J8S10_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAZ9630289.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            complement(3917..4312)
                     /gene="rbsD"
                     /locus_tag="J8S10_001704"
     CDS             complement(3917..4312)
                     /gene="rbsD"
                     /locus_tag="J8S10_001704"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002829567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HAZ9630290.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            complement(4340..5257)
                     /gene="rbsK"
                     /locus_tag="J8S10_001705"
     CDS             complement(4340..5257)
                     /gene="rbsK"
                     /locus_tag="J8S10_001705"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HAZ9630291.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            complement(5365..6378)
                     /locus_tag="J8S10_001706"
     CDS             complement(5365..6378)
                     /locus_tag="J8S10_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAZ9630292.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            complement(6459..7058)
                     /locus_tag="J8S10_001707"
     CDS             complement(6459..7058)
                     /locus_tag="J8S10_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAZ9630293.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            7244..7945
                     /locus_tag="J8S10_001708"
     CDS             7244..7945
                     /locus_tag="J8S10_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9630294.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            7955..10666
                     /locus_tag="J8S10_001709"
     CDS             7955..10666
                     /locus_tag="J8S10_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAZ9630295.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            11117..12745
                     /gene="treC"
                     /locus_tag="J8S10_001710"
     CDS             11117..12745
                     /gene="treC"
                     /locus_tag="J8S10_001710"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HAZ9630296.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(12805..13986)
                     /locus_tag="J8S10_001711"
     CDS             complement(12805..13986)
                     /locus_tag="J8S10_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAZ9630297.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            14238..15761
                     /locus_tag="J8S10_001712"
     CDS             14238..15761
                     /locus_tag="J8S10_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HAZ9630298.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            complement(15830..16558)
                     /locus_tag="J8S10_001713"
     CDS             complement(15830..16558)
                     /locus_tag="J8S10_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAZ9630299.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(16571..17851)
                     /locus_tag="J8S10_001714"
     CDS             complement(16571..17851)
                     /locus_tag="J8S10_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAZ9630300.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(17992..18594)
                     /locus_tag="J8S10_001715"
     CDS             complement(17992..18594)
                     /locus_tag="J8S10_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory regulator AgrB"
                     /protein_id="HAZ9630301.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            18839..19045
                     /locus_tag="J8S10_001716"
     CDS             18839..19045
                     /locus_tag="J8S10_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630302.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            19357..20076
                     /locus_tag="J8S10_001717"
     CDS             19357..20076
                     /locus_tag="J8S10_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAZ9630303.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(20157..20840)
                     /locus_tag="J8S10_001718"
     CDS             complement(20157..20840)
                     /locus_tag="J8S10_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HAZ9630304.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            21058..23244
                     /locus_tag="J8S10_001719"
     CDS             21058..23244
                     /locus_tag="J8S10_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HAZ9630305.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
     gene            23590..24000
                     /locus_tag="J8S10_001720"
     CDS             23590..24000
                     /locus_tag="J8S10_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HAZ9630306.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            24014..24370
                     /locus_tag="J8S10_001721"
     CDS             24014..24370
                     /locus_tag="J8S10_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HAZ9630307.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
BASE COUNT         8328 a         4419 c         4855 g         7280 t
ORIGIN      
        1 aaaagggagt gtgacagtgt cacatcccct ttttaattta ttctatttct ttaaaggcag
       61 atcaagccag aatgatttgt ctaaacttaa caaggttagt acaggaacag ttgcagcttt
      121 aactgtacga gtagttgttt ctggtatctg tcttgccgta aaattgttcc acaaatccca
      181 gattgaagcg acacggaaga tggaagaagc gttgttgacg cgttttatcg ttgaaaattc
      241 taatcctgtg attggcacgc catctgttgt ccatttgatt ggcacatcga atcgcttaga
      301 catattgagg atttcagcgt ttgcttcttc agttgttgct gcttcttttt tcggttcatc
      361 atattttgtc aggtcgtacg cttcgatgat cgcgttcaat ttttgtgaat attggcgatc
      421 tgtagcataa cgtccttcca aatatttggt tgcttctttg tagtcttttg tttccgactt
      481 ccaagttggt ttgtagaaat caggattgcc agtcagtcca tttttgatca agtcggcata
      541 gtcttccaaa ctttccttgt aagaaggata tttacggaat tgtgcgcgga tttggtagct
      601 ttgtccggaa ctatcttgtt caagtgtatt gaaggtcacg ctgcttcctt tatatgatcc
      661 tttgatacca aaaaggttat gatttggttc gcttgataat aagctgtttc cagatccact
      721 ttcaaggata gcttgagcca tcatgactga tgcgtagatt ccttcttttt gcccgatttc
      781 ctgtgcatca tctgcaatct ttttcaagaa ctgatcagtt gtttggtttt gactgaaatg
      841 gaacgagcca tctaatccat ctaaaataga tgagccgcct gtcagcgaac ctgaagcagc
      901 aggtaaacct gctaagttta ctcggacagc aaaatcaggc gtgaaatctg aaatagaagt
      961 tactcgaact ttatctcctg gttgaggcgc atggataaat tgtccgttcc caatatagat
     1021 acctacatgg tgagtaacac cggaagaagg tccccagaag acgaggtcgc caggttgggc
     1081 ctgacttact ggaatctgcg tacctgcata ttgctgttcg cctgtccagc caccgatata
     1141 atgaccggtt gctttcatat atacgtaata agtcaaacca gaacagtcaa aagtatttgg
     1201 accttttgct ccccatacat atggttttcc aagatgcttg aatgcttctc gaacgattgc
     1261 ttgttggaca ttcgttgtat ttgtaggcaa tacagcatca attggtgatt ttacaacaaa
     1321 atcagaagaa gcagaagatg gattctctat accgctttga tttgctgtat ttggacgaga
     1381 tgaagcattg ttcgttccgc cattcgatga accattgttt ggatggtttg gttctctctg
     1441 agtatttcca ttgttattcg atccagatgg gtttgtttga ttcgaagaat tcccgctgtt
     1501 cgaattattg ttattattgt ttgaattatt tgaaccatta ttattgttgt tattacccac
     1561 atctggtttg tttggcgttt ccggatctgg tgtactaggg acttcttcac taggatcagt
     1621 tggtttctct gttgaagtat ccggtccagc tttaaattct gcagtaatag ataaattgtt
     1681 cgtacctact gtaaaggtct ttgcatcata atttacttct ttggcaccat taacagcgac
     1741 tgaagcaatt tgttcacctt cagctggcgt aatagtgtaa gttaccttcg tttccgctaa
     1801 taaaccttct accgttccac tttccgtaat atccaaaggt tgctgttcag gggaatccgc
     1861 tgtcgaagca gtcagttgga tcttaccaat caaagaagga gcaattgtaa gggaatatgt
     1921 ctcggctggc ttttcatttt ctgatggatc agccggatca atttcagttg gctcggtcga
     1981 tcctgttgtt gagttagttg ttccagttgg gtcttctgta aaagaatccg ttgtttcact
     2041 agtagctgag ctggatgtag tcgtatctgt tgtgactgtt tgatcagcta tttgattatc
     2101 tacggcaaat acggtattgg tcgacaaaac agacggagca atcagccaag tagcagctag
     2161 caaacgtatc gtttttttat ttttcataat aaactagtcc ttttcctttc attgattttc
     2221 tgtcttattc agcattcatt agacattttt tggaacagat aatcgtgtcg aaaagctttt
     2281 tcttttcata aatctgtctg tgtattctaa ataaaacaat ttgtaaataa gcaacgagca
     2341 ttcattcgtt tttctttgac gttcatttta ttgcatagac cacctttgtt tggggataaa
     2401 caagtgggga taaaaatggt tatgcatatg taaattatac caaagtttgg aaagtatcac
     2461 aaaaatttat aaaaataatg atcctaaaaa gaaaaagact gaaatatgtg ataaacatct
     2521 catacttcag tctttttcat taactattca taagacatta ggtcttcatc aaacccgcta
     2581 acgagagtag tgatcattgc tacgactaga ctaacagcca gtcctgctaa gtaccagaaa
     2641 aaagtaccgg aaatgaatgc aggcaatgtg gtcagactac caaatacaaa agcgatcgct
     2701 ttcacttggg caaatcccat tacagctcca ccagcagctg caccaatgca agcagcaaca
     2761 aatggttttt tcaatgggat cgcaattccg taaacagttg gttcggtcac tcccgcaagt
     2821 aaaatcgaag caaaagcaga accggagatc gaacgggttt ttgaacgttt acttcgcaga
     2881 aatacaccta aagctgcacc agccattcca aaattggctg ctcctgtcaa cggaacgatt
     2941 cggtcgaacc cataagcaga gatattactg atcatgacag ggtttacagc ccattggata
     3001 ccaaatatta ccaaaatatt ccaaccacca gcgatgattg cgccactgat cggtccgtta
     3061 atatccatca tccaagtaat tgcggcagct aaaccttcgc caaggtaaac acccgcaggc
     3121 ccgaatacca ttaacgtcaa aggaaccgtg ataactaatg aaagtaaagg tacaaatact
     3181 aattgcatat tttcgcgaat atattttttg aggaattttt caacaaaaga ataaaagaaa
     3241 atacctaaaa tcgccggcat gacagtagac gtatactgca tcagtactac aggaatcccc
     3301 agaaaatcag tagctgcttt gccactgtct gaaagtaaag aggtcagatt cggttcaatc
     3361 agtgctgcag caatgacagc cgcaatatat ccattcactt taaacgtttt ggcagcagaa
     3421 aaagcaagaa agattggcag aaaataaaag acggcattcg acgcagcaga caaaatatga
     3481 taagttccgc ttgtttcact aagccagcca atcgtagtcg ctaaaacaac cagacctttt
     3541 aatataccag aaccggcaaa cagcggaatg atcggcgtaa agatttccga tatcaaacca
     3601 aatagttttt cgatcggatt tagcttttct ttcggagctg aatgatcgat ttgacgcgtc
     3661 aattccttgt aagcaggagc caatccctga tccatgatta tttctgcata tctatcgagt
     3721 aaaatgaaat acttaatgga agggatttgc tgttttaatt tttctgcatt ggctactggc
     3781 tgttttttca atttgatacg aagccgagtc gcacatggaa ggacagaatc aatattgtct
     3841 tttcctccca actgttcaat cagcatatga atctgctcgg acagtaccat ctgttcagga
     3901 ttcattgtcg tttccattag aagaccactc cactcactaa tataatattg gcgtaaggtg
     3961 tcatttcgcc tgtacgaata aatgcatgac agttattcaa ctcttttttc atttcttcat
     4021 gtgggataaa gctaatcggt gtatctggta acaataattt gattttttcc aatatttccg
     4081 ggttcattgt ctttatttct tccgccaatt caatcgattg tacctcaagt tcttctaaaa
     4141 cgttttctaa aacagataaa aaacttggaa gaccgtttga gacagccaaa tctatttttt
     4201 cagtaccaaa ggggacaggc atgcctgcat ccccgatact taatttatca aagtgcccca
     4261 tttgtgcgat tactcgtgaa atatctgaat tgattacttt tccttttttc atgtttgttt
     4321 cttcctctca ttgttaattt tagactgctg attgttctaa agcttcgcgg taagggatag
     4381 aaggttgcgc accataagac tgcacagcaa cagaagaggc tagatttcca taaaggatcg
     4441 cttctttcaa gttactaagg tctggctgaa gtgtgctgct taatgcgcca ataaatgtat
     4501 cacctgcggc tgttgtgtca acggcatcca ctttaaaagc agggacgata ccgtgttctt
     4561 tttctgtatg atagaaagcg ccggcactgc ctagtgtaat gattactgtt ccaataccta
     4621 attcatggag tttttcggct gctgcgacca aactgttatg atctgtcact ctgattcctg
     4681 taatgatttc tgtttctgtt tcatttggta taatgatatc tgtcttttca agtagttcag
     4741 taggaatcgt ttcacgagct ggtgcaggat tcaggatcgt tgtttttcct gcgtcttttg
     4801 caatagaaaa agctaggatc gtcgcatcta agctactttc aaactgagca ataataaagt
     4861 cactgtttgt aatcagttgc ttgtttttta ggacttcttg ttcatggaaa gcattatttg
     4921 cccctgcatg gatcaagata ctattttctc ctgctgcgtc taccataatc attgcttgtc
     4981 cggttgtggc gccttggatt tcagctatcc cagatgtatc gatgttttct tttgtcagta
     5041 gatctaataa ctgttgtcct tcgctgtcag ccccaacgcc tccaataaaa gatgtccgtg
     5101 cgcctgaacg tttggctgcc actgcttggt tggcaccttt acctccgcca gcgtgaaaaa
     5161 tctcatgcgc atgcatcgtt tcgcctggct tgggcatgtt ggttaaacga agggtagtgt
     5221 ccatattaat acttccaatt actgtaaccg tgttcatttt acaaacctcc aactatctca
     5281 tttattttga tgggaaaatt attttttaaa acgttttagt aaaacgtttt aatagttcga
     5341 taaaaatata gcacaccttg aaagctattt caagggtgca gttgaaaatc ttttttctaa
     5401 tcgtacaggt aatctttttt cttcccattc tttttctggg aattggatcc gatctaacaa
     5461 taacttggca gatgtttgtc ccaattcgaa gattggttgt gcgatcgttg tcagtttcgg
     5521 cttgatatac tcgcacatat ctatattatc atagccaata atgctgtagt cttcagggat
     5581 gctttttcca gcttcctcta atccgcgata taatccaaaa gctaattcat catttaaagc
     5641 aaacacacca gttgcagcag aatcaagaag ttctgctgtg atctggtagc caccttgttt
     5701 tgagaactgt gtaggtaaga ggatcagttg gtcgtgaggg atttggtaaa catcaagagc
     5761 agatttaaac ccctcaatcc gagcgtggac attttccggt ggattttcag gatagacaag
     5821 ggcgatcgtt tgatgtccta gactaagcaa gtgcatgccc gctaggtaac caccgcgaaa
     5881 atcgtctgtt cgtacggcat cactaaatcc ttcagatttt ttctgatcca aaacaatgaa
     5941 gggccggcct tgttttttca aattttcgtt gattgcatct gtagagacag cagaagtcgc
     6001 gataatgaat ccatccacac ctcgacgtgt gagctcggct agatattcga tttctttttg
     6061 atgatcagaa tcagcattac ataatatcgt gacgaaattc tgcttataca agatatcctc
     6121 aattcctcgc atcagtgtac tgaagaatgg attcgtgata tcaggaacga gtacaccaat
     6181 tgttttcgtt tccttggtaa tcatttgtct agcaaaatag tcaggctgat agcctaattc
     6241 ttctttggca gctaaaactt tctgaacagt tttcggactg aatttctccg tatttccatt
     6301 taatatcaag gagacagttg tgattgaaac gccggaaagt ttagcgactt ctttgattgt
     6361 gatctttttt ttcaccatgt tcatactcct atctaaatcc tgtggttatt ttcccatgaa
     6421 atcaaaaaga agtaaatgaa aatcacgtgt gccagtactt atttgctttg ttggatagct
     6481 tcgattattt gtttcgttga gcgtactcgt gcagttttcg gaaatatctt ttttatgaac
     6541 aattgatggg attctttgtc acgatcactg caagcatctt cagcaagcac gatatggtac
     6601 ccgtgttgaa aggcatctaa tgcagtagca tatacaccgt ttgttgtcgc tacaccgctt
     6661 aaaatgatag tttcgattcc acgccggcga agttgaagat caagagaagt accaaaaaaa
     6721 gcacttggat tgtattttgt gatagtcaac atattatctg tatctttcaa agaatccttc
     6781 aaaagtaaat cagtgaattc tggaggtaca gaagcagtca ttccacccat atcagtttgt
     6841 tgactcaaat aagggaaagt ggagatgtct acgttcacta aaactttcaa ggcagcggta
     6901 cgtttcaatg ttcttactaa caaatcattg tttgtcagaa tagatgctgc agtgtgtgga
     6961 gagagtgtac cgttatttac gatctctttt tgcatgtcga tcgcgacaaa agcagttttt
     7021 gataaatcaa aaatcatatt ttcctttaaa tcattcatga tgttccttct ttcaaataac
     7081 aatgtttttt atgtaagtaa atcataaatc gtttatttgt caactaaatt aaaggattcc
     7141 tttctttagt ctagagaaat tcagtggtaa aataaataag tgtgagaaaa cgcattcgat
     7201 gcatagatat agcgagaaat atcgtgaaaa tggaggaatc agagtgaagt atgtcgaagt
     7261 aaaaaatgaa tacaaacgat acaaaatggg agaaacgacc attacagcaa atgacgatat
     7321 ttctttttca attgaaaaag gcgaattagt gattatactt ggtccaagtg gagcaggaaa
     7381 gtcaacgatt cttaatattt taggtgggat ggatacacct gatgaaggtc agatcattat
     7441 tgatgacaca gatattgcgc aattttcaga taaacagctt actgcttacc gacgaacaga
     7501 tgtagggttc gttttccaat tctacaatct cgttcctaat ctaacagcaa aagaaaatgt
     7561 ggaattggca acggaagttt ctcctgatgc gcttgatcct gtagaggtat tgaggcaagt
     7621 gggcctagct catcgattga ataactttcc gtcccaatta tcaggaggcg aacagcagag
     7681 ggtttcaatt gctcgtgcac tagctaaaaa tcccaaactt cttttatgtg atgaaccgac
     7741 aggcgcgctg gattttgaaa cgggcaagca agtattgaaa ttattgcaaa acgctagcag
     7801 acaacacggc aataccgttt tgatcattac acataattct gctttagcgc ccatcgctga
     7861 tagagtcatt cacattaatg atgctaaagt aaggtctgtt gaattaaatg atcatccttc
     7921 atccattgat gagattgtat ggtaggggga ttttatgaaa acaagaacat atcttaaagc
     7981 aggttttcgc gaaattcggc aatctaaagg acgattcatt gcaatcatcc ttattgtcat
     8041 gctaggaaca cttttatttg taggtgtcaa aactgctgga cctgtcatgc aaaaaacgat
     8101 ggatcactat gttggtacag caggactttc tgatttgcaa atcgtttcta ctggtggctt
     8161 gacacaaaaa gatattgctc aagcagaaaa gatcccagat gcaaaagtag aaacaggaaa
     8221 acagatctat tattccaata ctggcaaaaa cgaagtgatt caaatatttt cttataacaa
     8281 aaataacaag cagaacaagc tacaattaac tgatggaaaa ctcccggaaa aaccaaacca
     8341 gcttgtattg gatgaaaaag cggaagatga agggtataaa atcggtgata tttatcagat
     8401 tgattcagat gaattgaaag aaaaagagta taccatcacg ggctttgtcc gttctccatt
     8461 gttcatcaac aatttggaga gaggatacgc gaacgtcgga aatggtagcg tcgattattt
     8521 tgtctattta cctgaatccg tttttaaaac agatatttat tctgtcttat atcttgattt
     8581 tacaaacgta aagaatttga atacgtacag caaagcttac aaagataaaa tggagcaaaa
     8641 tcaagaaaag gcagaaaagt atttacaaga tcgacccgaa gaacgcttag aagagctgaa
     8701 aaaatcggcc aacgaagaat tagaaccggc acagcaaaaa atagcggatg gcaaagcaca
     8761 aacaacgcaa gcaagaacac ggttagaaga tgctaaaaaa cagttagcgc aacagtcagc
     8821 aactatccag cagcttcctg aagcgcaacg aacaatcgct gttcaaacat tatctcaaca
     8881 agaagctcaa cttgctgaac aagaaaggca attagttgag aaagaacgtg aactggcctc
     8941 tgcagaggaa gaattgaatc gaaatgcaga aaaaattgaa aatttaacta aaccatcata
     9001 cctatacaat gaacgttcag aaaatgtcgg ttttcaagaa tttggtgatc tgtctgatcg
     9061 tatcgctgcg attgccaatg tttttcctgt tttctttttc tttattgccg cattgatcac
     9121 ctttacgaca atgacacgta tggtagaaga aaaccgcagg gaaatcggga cattaaaggc
     9181 gttaggttat acgaaagttg aaatcgcaaa aaaatatgca atctatgcaa gtctagcctc
     9241 agggataggt attgttttag gaacgatatt aggaacgaat cttttgccaa ggatcatttt
     9301 tgagctgtct aacgagcggt atgatattgg gagtgcgctt attttttatg actggccgcc
     9361 gattttacaa gcagctgccg cattcttcat tgccgcattt ggcgctgcaa tgatcgtttt
     9421 attcaaagat ttaagagaac ggcctgctgc attgcttcaa ccgaaagcac cgaagccagg
     9481 gaaacgcatt tttcttgaat acatcactcc gctgtggtca cgccttagct ttaatcaaaa
     9541 aatcagttac cgaaatctct tccgatataa gtcaagaatg cttatggcga ttatcggaat
     9601 tgctggatgt gccgggctga tggttgcagg cgtgggattg aaagattctc taagttctgt
     9661 ttcagccaaa caatttggac cgatcattga ctatcaagca atcgttacat tggattcatc
     9721 cacggaagat agtcgtcaaa aagcagcgga tatgctgcag aagcaagaaa aagtaaatga
     9781 gatcctagct attcatactc aaaccgtaga attgagaaaa aaaggacatg cttcgcaaag
     9841 tctgacagtg atcgtaccaa gtaaaacagc tgatttggat cgttttatcc atttaactga
     9901 tcttgaagag aacccacgct ccttgcctaa aacaggaatc gctattacgc aaaaagtagc
     9961 agaactattt gacttatcta caggagatca tatttcgctt tatgatgaag atcaaaaaga
    10021 atggaaagtc gaagtaaaag aaatcgtgaa aaactatcta ggtagcttta tttatatgtc
    10081 ccctgaatat tatgcttcag ttactgatca atcgatgatg gataatgcat ttttgctgcg
    10141 tacagataag atgacaacaa aagaagaaga aatgctttcc gagaaactgc ttgccacaga
    10201 cgctgtgaca aatacgtctt tcatgtccaa acaaatcgaa acgcaagaag aatcaatggc
    10261 gaacttagac tcggttgtct taatctttgt cgtattatca ggactgctgg cttttatcgt
    10321 cttgtataat ctaactaata tcaatatttc cgagcgtgta cgcgaattat ctacaataaa
    10381 agtccttgga ttttttgata aagaagtcac gatgtacatt gttcgagaaa atatcatctt
    10441 tactctttta ggaatcatcg gaggatttgg tgtaggatat atattgactg acttcatctt
    10501 gcaacaagcg tctatggaga atgtcatctt tccattagtg atcacatggt gggcttatgt
    10561 cttatcagca ggattaacta tcgtatttac ggttattgtg atgattgtta cccatttcaa
    10621 attaaagcat atcgatatga ttgatgcgtt gaaatcgaat gaataaaaac agaggttgtg
    10681 aaatcagcgg tttgacctga gtattagaga aacaaacggc aaaatagttt ttcatatttt
    10741 gccgtttttt gagctaatac cgaaggacag ctgattgaac accatgaatc agaggttgta
    10801 aaaaagccgt cctgcatcga gcaaaaagaa tactcaaata aaattagctc ctcatgtttt
    10861 acatttgaga agactgattg ccgtagataa aagcttttga acaccattta tagaagaaac
    10921 aagaatattt tgctatttta aacaagagga tagacaaata catgtctgat ctcttgtttt
    10981 ttattgggca acagacctct tagaatgtat aaagataaat tttacaaacg ctttcggttc
    11041 agttataata ataaatgata acttgtatat ataagttgtg gtaggtaata aatcagttga
    11101 atggaggtaa atatccatga catttaaaga caaagtcatt taccaaatct atcccaaatc
    11161 ttacaaagac agtaatggtg atggaattgg agatttaaaa ggaatcaaag aaaaactccc
    11221 gtatctgaat gatctaggca tcgacatgat ttggctaaac cctatttatc caagccctca
    11281 aaaagacaac ggttatgata tctctgatta cacagccatc gatcctatct ttggtacgat
    11341 ggaggaattc gaacagctaa tagccgaagc aaagaaatac cggatagaaa tcatgctcga
    11401 tatggtgctg aatcacgttt cgacagaaca tgaatggttc aaaaaagcac tagcagggga
    11461 ccagcattat caggacttct tcattttaag agaagagcca acggattggg tatcaaaatt
    11521 tggtggaagt gcttggtcgc catttggaga tacggggaaa tattatttgc acttatatga
    11581 tcggacacaa gctgacttga actggcggaa ccaagcagta agagaggaac tattcaaagt
    11641 tgttcgtttt tggatggaaa aaggggtaaa aggattccgt ttcgatgtta tcaatgttat
    11701 cggtaaagac gaacaattga aaaataataa agaaaatgat ggcaaacctg aatatacgga
    11761 caaaccaatc acccatacgt atctaaaaga attgaaccaa gcaacgtttg ggacggattc
    11821 cactatcatc acagtcggtg aaatgagctc tacgacgatc gaaaattgta tcttgtatac
    11881 agaacctagt agagaagaat tatcaatggt ctttaatttc catcatttga aagtcgatta
    11941 tgaaaatggg aataaatggt ctactcctcc atttgatttt gcagaattaa agcgactatt
    12001 tcatacatgg ggagaaaaga tgagtgaggg taacggctgg aatgctctat tttttaataa
    12061 tcatgatcag ccacgtgcgc tcaatcgatt tgtagctatc gatcagtatc gaaaacaagg
    12121 agcagagatg ctagcaacca tgatccattt gaaccgtggg acgccctata tttatatggg
    12181 agaagaaatc ggcatgatcg acccagacta ttcatcgatt tccgactata ttgacgtaga
    12241 aagtttgaat gcttataagt tactccttga acaaggattc acagaaaaag aagcgtttcg
    12301 tcggatcaaa gcaaaatctc gcgataactc tcgaacaccc atgcaatggt cagacacaga
    12361 acaagcagga tttactacag ggaaaccttg gttaaaagtt ggaggcaagc tagaagagat
    12421 taatgtagaa aaagaactat cttctgaaga ttctattttg tcctattaca agaaattgat
    12481 tcggctgaga aaaacatatc caatcgttgc acaaggagat tatcatgctt atgaagcaaa
    12541 tcatccggaa gtttatggct ttcttcgcca atttgaagga cagcagctgc ttgtattaac
    12601 aaatttctat gataaagata caaggatcgc catcccagaa ggattcacag aagccaatat
    12661 tcttatcgat aattattccg atactgttct tcatcaaagt ctggagctaa aaccatacca
    12721 ggcaattgct ttgctgaaaa attaaaacaa aaacacaaaa cgtcgttcct acgagctatt
    12781 ctcgtaagat cgacgttttg tgttttattt aaaataatct tcttcagaaa atgaagagtt
    12841 ttcatactct cctttatcgc cataaaattt attgtagcgt tgtttgaatt tacggaaaat
    12901 aaaagtaacg agtaatttga ctaacgtata gataggaata ccaaaaataa cgcccacaat
    12961 tcccattaga tcacccatga caagtaaaac gattaagatc gtaatcggat ggatctgtaa
    13021 acgatcaccc attactcgag gaatcaccaa gtcaccgtgg agaagttgta cggcaaacca
    13081 gacaatgaca aatttgacag ccataaaagt agagtcttgg aatgcaatga tcaaacctgg
    13141 aaagaaggcg ataaacggcc caatatatgg aatgatacat aacaacccag cagaaatagc
    13201 taaaacacta gcaaattcta atccgatcag taagaaacaa acccagtaga ctgctccaag
    13261 gataaatgaa gcaatgattt gcccctttag aaatgaaccc aattgttgat tagcaatctt
    13321 tgtcaaattt ttaaaatctg tacgaaatgc tggtgggaca atcgctaaaa ctgactgata
    13381 aaatttttga ggatctctca aaaggaaaaa agcgacaatt ggaccagtaa ataaagtaat
    13441 aaaaatagct gtaacagttg aaaaaatgtt gctgatccgt tgtgcgccac tttcccaata
    13501 atttccaata aatccagcta tatcagacgt cacgtcgtca atagaagcga aaaattgatt
    13561 aaatgaatcg gcaaaaggtg ttttctccaa aaattgtcgg agactctctt gaaaatcttg
    13621 aaacaaatct ggcaaactac tgatcaatgt ctttgcctgt tcttcaagaa aaggaataag
    13681 ccatatgctt ccaagcccca ataaaaataa aataatcaca taaacgataa tgactgacaa
    13741 gttcctcgaa aggtgcttgc tcaaacgttt gatgactggt tccaaaagat aatacaagat
    13801 cagtgcaaac aataatgggg gcaagatagt agcgataatg attccgacag gcttgaatat
    13861 aaacgagatc tgatggaaaa aataaatgat cagcgcaagt aagataacta ttcctaaaac
    13921 atagtaagag gtttttcctc ctaaaaagcg gatcaaacga ttcgttgtat ctgtttcttt
    13981 tttcactctt tttcctcctt tatctataac ttcattatag acaaaagcgg gtataaaagg
    14041 aaaatgatag aggttgattg caaaaatatc gtcaatcatt catataaact ttctcatcaa
    14101 ttaaaataag aaaacgcttg acagttcttt taaccatatg ataaattaaa tcctgttgct
    14161 aaaacgtaac tattacggtt tgcgaaaagc gaatcggaac attcaaatga aagaagatga
    14221 gaagaggagt gtcataaatg aaacgattga taggtatatt ggccatgctg gttttagcag
    14281 gtatgttaac tgcttgcggg gcaagtggga aagccgagga cagtaaagaa aaattgagcg
    14341 tgatgacgac cttttatccc atgtatgatt ttacaaaagc aatcgtcggg gatgaaggag
    14401 aagtagagtt attgattcca gcagggactg attcccacga ttatgaacct tctgctaaag
    14461 acatggcaaa gatccaagat acagatatct ttgtttataa tgatgaaaac atggaaacat
    14521 gggtccccgc aatccaaaaa acattacaag aaggcaatgt ccatacgata aaagcgacag
    14581 aaggtatgct tttacttccg ggaagtgaag aaggacatga tcatgaccat gaacacgggg
    14641 aagaaggcca tacacatgag ctagacccac atgtatggct agctccaagt ttagcaatca
    14701 agcaggtagc aaacatacgt gatcagctga ttgaagctta cccagaaaaa caggaagtat
    14761 ggacaaaaaa tgcagcagcc tataccgaga aacttcaagc actccatcag ctttatcaag
    14821 aaacctttaa gcaagcaaaa caaagatctt ttgtcacgca acatgctgca ttcaactatc
    14881 tagcgttaga atatggattg aatcaagtat cgattgctgg tctttcttct agtgaagaac
    14941 cgtctgcggc gagaattgct gaactgaaac actttgttaa agaacatgga atcaactata
    15001 tttattttga agaaaacgcc aaagatagta ttgccagaac gttagcaaac gaagcaggtg
    15061 tatctttaga agtattgaat cctttggaag gattgacgaa tgaacaaata gaaaatggag
    15121 aaaactatct ttctatcatg gaagcaaacc tcgaagcgtt gaaaaaaacg acagagacag
    15181 aaaacccgct agaagatact ttgaccccca aaaaagaaaa gagcgtctac aacggttatt
    15241 ttgaagacga ggatgtacaa gatcgctctc tttcagattg ggcaggaact tggcaaacag
    15301 tagatacgta tgtagaagat gggacttttg atcctgtttt tgaatataaa gaaaaattga
    15361 atcaggataa gacagcacaa gaatataaag aatattatac gaagggctat caaacagata
    15421 ttgcttcaat caagatcagt gagaaagaga tggcatttac gtttaagaat ggaacaacga
    15481 aacgttcaaa ttatcgttat gtagggaaag aaatcttgac ctacgaggca ggaaaccgtg
    15541 gcgtaaggta tctattcgaa gcagaagata aggaaagtgg cgcttttaga tatattcaat
    15601 tcagtgatca cacgattgca ccggctgact ccgaacattt tcatttatat gcaggaaatg
    15661 aaagtcaaga agtattgctg aaagaaatgg agaattggcc aacattttat ccagatacaa
    15721 tggatggacg tgaaattgca caggaaatgc ttttgcactg ataggcaaaa aagaaccgaa
    15781 gggtttggat cggctggtca tttagtcggt ccaaactatt cggttctttt tatgaaatca
    15841 atttctttaa tccacggata gaggctggga tggtctcgcc gtttgccaac gtgacttctc
    15901 tggttttttt attaatcgac cgcacatttt gtgtattgat aacataggat ttatgacaac
    15961 ggataaaatt ccgatgcatt ttctcgattt ctttgatctt ctcatagaat tgtaattggg
    16021 catgagtcaa atggacttcc agtttatgtg gcgctcctag cgaagtagaa aaatattgga
    16081 tgtctttgat cggtaaaaat ttgatctcat cattaaactc tattttgaag atatcttttt
    16141 ggatttggga catttgaaaa tcttcgaaaa ttttgctcag gatatgctcg acattttctt
    16201 ttaaatcata aagatcttct ttgacgatat aatcagtcgg ttcgatgttg ctttttaaga
    16261 ttttcatcga catttccgta tgggaagtca catagattat ttttcctaaa ggatctaatt
    16321 cacggatcaa tttaccgatc gctacaccat ccatttcact gtcttctagt tcgatatcta
    16381 aaaagtaaat accaaaagaa gaagttctga tcttggctgc attgagaagt tcttccggat
    16441 cagaggtaga aatatggaca taactgtcta agttttcaat catgattcta tttttgatca
    16501 ccgttgataa aacttctaat tgttttggat cgtcttcaca aatataaatg ggaatcatat
    16561 cattactcct ttattttatt tgtatataaa tcgtttgaga aaaacgctgg ttttcaattg
    16621 atgtttcaag gaaaagataa ggattggtct ttgtcaattc atccaagata aacaagccaa
    16681 ggccttcgtt ttttggattt gtttttgttg agaacccttt ttgtttcaac tggtttaacg
    16741 gtaatgtatt tgttgttgta ttgatcacac gaatcatcac ggaatgattc ttcttgagta
    16801 tggtcaattc gatttttttc ttctttgcag cactagctcc ttcaatcgca ttgtccaaga
    16861 taataccaag catacgtaca aggtttaccg tatgtttcgt atccagttcg attggctcag
    16921 gaaaatgaag ctggacgatc aacccttttt cctgtgccat catgagtttt aatgacagta
    16981 aactacggat ctcaggaact ttcatattat ccaacatact tagattggcc ggaaaaaggt
    17041 tcatcatctg gcgtgtaggt aatatcgttt gatcataata agaccgtaat ccttctaagt
    17101 cgccttctga aatatagctg tgaagagaaa aaagcagatt ttggtaatca tgtttgaatt
    17161 ctctcaagtc ttgatagttt ttttctagat ctttgatata atcctgttgc atcctgactt
    17221 gttgctctaa taactgatca gctaatttct tattagagat tttccaataa taaaccaaga
    17281 tgatcaggcc aacacacaga tatagaatga aaaaactcgt attcaaagct aagacatcag
    17341 gtgtttcacc agaaaaacgg gtataaaaaa taatgatata gtatgtaaat aatatcaatg
    17401 tcccgatcgt accgatcata cggcggtcca cagtgtgaaa ccaagtctct aacgattttt
    17461 ttaaacaaaa agctaataaa gcagataaaa aagcggataa gacaatgtga aaatactgca
    17521 atgaatctcc tggttcaata accgaagatt tcaaaacaaa aaaatcgccg atgcttgtta
    17581 agtgatctcc taaaagcgac gtcaataacc caaaaggaag cgcgtaaacc aattgttgac
    17641 gcgaagtcga aaagaagaaa aaagtaagca tcagcattcc tatagcaatt agagcagtaa
    17701 aaatccctaa aatcgaatag acccatccaa tcaaaataca agaaatcaga atgactcccg
    17761 caaacagata tttgtatcgg atgtgatggt caatcaataa gatacaaatt gtgtaaatca
    17821 aatattgcaa cgctatggac cataaaaaca taaagtacag ctcccattga tttttaccaa
    17881 attatagcac aattggcgta ttattttttt aatttttcag ggattttgaa ttcagaactc
    17941 ataccaaagc agcagccaga tacaaaaaag tcagataagt tagttaattg tttaatgatt
    18001 gtttttttca tgaaagattc ctccaaaatt catcaagtag tttgtaatag gaagcaacgt
    18061 agctatttct aaaacaatcc caagtagcaa ataggtagaa aagtaagaag ctgagaaaaa
    18121 taacgtaatg agagaaaaaa ttagaaacat gctgatcgcc ttctttaata atgggggacg
    18181 tttctcgggt tcaatgggat tgattgctgt acctcttgat ccatagcgaa gcagtaacaa
    18241 aaagcagctg attaacaaaa agaccatcat tgggaaggag atagtcaatt gcagatgttt
    18301 catcaccaag ggaacgcccc ataaataaag tagtgtccac agcagacaaa cgaattcaga
    18361 gtcggaatgc aatccataag catatctgcg gatgcagata taagaaagaa aggtgattcc
    18421 tgtttccgcc catgagcctg tcaccagaga aaagactaga acgaccgcta gttttccaag
    18481 attattcaat aaaacttcta agacaaattt tacttggaca tacaccatat cttcttccga
    18541 tttgtctccg ctgaataagg cttctaataa tttgttcaca actttatctt tcatctcata
    18601 cgtacctcca ccacaaattt tatgctaaaa aaaataaaaa acgtcttttg tttcataaaa
    18661 agtggttttg acatcaaaac cgtcatgatc tcctaaaaaa atcttcgttt tccaagaacc
    18721 ttaccaaaaa aagtgacagt tttgatacga aaagtacttt ttatgacaag tttgtgcttt
    18781 ttcgagtgat ttatgttaaa aaattactga ccttataaaa ggtgatggag ggattcttat
    18841 ggaaaatgaa caattgtttg aagtcggcga aacatatgca tttaaatctg atttatttga
    18901 atcaccaata aaaggaaaaa tagaaaaaat ctatgaaaat agtgtgatga tacgtgtcat
    18961 gaaatgcgca gtagaagaca atgataccgc tcataatctg cactggcagt tagttgtacg
    19021 caaatcaagt acaatagaag aataaaaaca gataaaatgt tgagagcata aagaggttgt
    19081 gagtctcccg tttagctctg agttacaagg aataatgtta aaaaacagct tttcatgttt
    19141 tatgaatatt gccttgtgac cgaggtgttg gcaggagaat actgtttatt tgaaaaaagg
    19201 gctgcgacaa gacttttgtc acagccttta ttttcatgaa taggagttac ttttggctac
    19261 ttttagagaa gtagctttta aggagcagat aaagtcaagg cttttatttc tataaatgaa
    19321 gtagtaaaat gaagaacaga ttttattaca ggaaggatgc cgataattgt gatcattgtt
    19381 gcaggaacga tcggtgcagg gaaaagcaca ctaactgaaa tgcttgccca agatttagaa
    19441 acaaaacctt tttatgagaa cgtggaagat aatgaagtat tgccgctatt ttattctaat
    19501 ccagaaaagt atactttttt attacagatt ttctttttga acaaacgctt tttggcaatc
    19561 aaagatgctt tcagccatga tgacaacgta ctagaccgct ccatctacga agatagtatg
    19621 ctgtttcatt tgaatgcaga tttagggcgt gtttctgaag tagaagtaaa gcagtatgaa
    19681 ggtcttttag aaacgatgct gaaggagtta gaagaaattt cgccacaaaa gaaaccagat
    19741 ctactggttt atattcgtgt atcctttgaa actatgttag cgagaatcaa aaaaagaggc
    19801 cgggaatatg aacagctaga acaagatcct gaactctatt cctactataa agaactcaat
    19861 cgacgatacg aagagtggta tgaacagttt gatatatgtc ccaaaatagt gatcgatggg
    19921 gacaaatatg atttcgtagc cgatccggca tgtggagaac aaatcgtaca agaaatcaag
    19981 atgcgggcaa agaaaatgac agaagaggca gatgcccagt cgatccgcta cactacaaat
    20041 aacccgaaag caaagggaat ctttacaact aaataatata aaaactaagc aaattgctca
    20101 ctcgcagata tttctctgtg agcagcatct tgcttagttt ttttgattca ttgagatcaa
    20161 atagtgaacc gattcgtatg ataaaattgc cataaatgaa atgtctgagt gagggccatg
    20221 atcaaaaata aaatggaaac gatcaaaatc gaatgggcgc caaacagatg atgacagaaa
    20281 acaaggacaa tagctcctgc gataaaggca agaacgacac ttagatagtg gaaaaatcga
    20341 tcaaaatctg ctttttcttt agaaatacaa taatcatata agttcgttgc tacccctttt
    20401 aaatttccag ttgtaaataa attagtgtag gcacgcccgt tgattttatc aaaagctacc
    20461 cactggatcg atgcagtaaa agcaatcaaa atcgttacta atgcgggatg ctcatggacg
    20521 ggtgtcaaac taacaaagaa aaaaatcact gcttcataat atagaacaaa caagcgccag
    20581 aaatgttttt ctttttttct aaaataatca attagatact ttgttagaag aatccctaag
    20641 aaaaagaaaa gggtagacaa tactttttta ccaacactta gccattctcc gtcaaatgct
    20701 tggatgatcg atagaatgat attgccagtt tgagcagagg caaaagcacc atattggata
    20761 taagtataac tgtccatggc tcctccgata aatgtcagca aaagtcctat tgtacgcccc
    20821 tcgtgaaagg aagtctgcat ttttttcatc accttttatg aatatttttg tcttccttat
    20881 cttagcataa acgattgaaa aaaaggaaaa attttcagaa aactaaaatc atatcgcttc
    20941 ccattttcat ttttagaaag gtctgttagt ataaagaaaa aatagacaac gaaactttaa
    21001 ataaccaact tgaaataaac aaattcaaag aagaaagatg ggaaggaaat caatcagttg
    21061 aatgaaaaag aaattctccg attacaaaaa gaattgaaac gctgggagaa caagtataaa
    21121 aagcttcaac aagtctttcg gctacaagaa gaaatcattg ctacctatga agcggcttat
    21181 ggcgaagcac ccggacttat tgaggaagaa gtacaagtaa aagaaagtga aggaaacagc
    21241 tctttcttta aaatgatgga gaaacgttcc tataatcgct tcaatcaaga acaaaaagca
    21301 gctatcacat atgatatgaa gaaacatctt cgaatcatag caggagctgg gagcggcaaa
    21361 acgcaaacaa tctgtgcaaa agctgtttat ctgatgacgc aaaaacaagt agacgaagaa
    21421 cgcatactaa tgatcacttt tacaaggaac gctgcaaatg aactaaaaaa acgagtagat
    21481 aatttcagcc agagaaaaac cgctgtccat atcggaacat tccatagtat cttttttagg
    21541 atatacaatg aaatttgtcg aaaatttcct gaagtagcaa tgcaaggaat acaaggagac
    21601 ttttcaaagg atactgcaca aaaagtgaat gctgttttgc aacagctgat acgtaaatat
    21661 aatctttata tatttgatca atatggagaa aaaacgattg cttctcggtt agactattgg
    21721 cagaatatga acctttcagt agaagaaatg gttcagttag ttaaagaaaa atatgattcc
    21781 attgataaga atgcacgaca gccgatatca gaacgactgt atggattgct cacggaactc
    21841 caagaacaaa aaagaagcca gcaattgcta gagttcaatg atgtactcca aaatctgaaa
    21901 agcgctttgg agaatgagga gatccagcat tatatcggcc aaaaatatga ttatctattc
    21961 attgatgaat ttcaagatac taatccactt caatgggaaa tcgtgaaacg gatgacaaag
    22021 gaaaacagga tcaagttgat tgttgttgga gatgatgatc agagtatcta tggattcaga
    22081 ggatcagagc cagcatacat caagaacttt gaaaaagaat atcctaccaa aactcttttc
    22141 ttattaacta attatcgttc tcgggcagct attgtccaag gagcaaatag attgatcagc
    22201 tataataaaa atgatcggat accaaaggcg atgattccag cacaaaaaga agcaggtgtt
    22261 atggaagcct atttgttttc tgatactaaa gcagaaagtc agtggctaat caaacaaatt
    22321 cagacattta ttcaaaaaaa tgggaaatat aaggaatcaa tcatattata ccgatcagct
    22381 tcacaaacgc agcagcttgt ccaatctctg ctgaaaacga atattccttt tgtactggaa
    22441 gcagatagtc catatgaagg tatctttggt atcaagtctt tccaacattt ctatcaaaaa
    22501 attgttcatt ggcaaacagc actgaatctg caaaagaaaa atcaggccta ccagcaattg
    22561 ctccggcagc tgatggcaga ctgctacctg aaaaaaagtg aatgcgatca atacttttct
    22621 cctaaatatc aaaatatagc cgttgcagat tatattttgt cgataagccc caatttaaaa
    22681 tcgaaatctg cagaaatccg agagtttgag gaagcgttgc gtaaaacaga ccagcatcaa
    22741 gaaatctatt cgcttgttca aagctatctt catctgccac gtatagctaa ggaaatcgac
    22801 cagagtgatc aagaatggat acgagaagaa gtaaagcagc atgctacttt cagaagactc
    22861 caagccttat cgcaagaaac ccaagcgaca gctaaagaat taaaaacccg cttgattgct
    22921 tacagacaag gaaaacttga tgcactatgt atccagagca ttcacaaaag taaaggtctt
    22981 agttaccgaa atgtcttttt gattggttgt aacgaaggaa gtttgcctta taacggagcg
    23041 acagaaaaga aagtaatcga ctttaatgaa ataaaagcag aaccagtaac gacgatagaa
    23101 gaagaacgaa gactatttta tgttgcgatg actagagcaa gaaatcgtct gtatctatgt
    23161 gtacctcaaa tgaaaaattc aagaaaattg aaagtatcga gatttatcaa agaaaccggg
    23221 agtcgtgtga aaaaaggaaa gtgatagaag agagggtgtg acagaagtgg tcagtttcaa
    23281 gaaagaagaa ggaatgtacg aaaattgctt ctcaaatttt tgtgaaattt cagcttattt
    23341 tcgaagaagc tatttctgga acacagttta ttcggaaaag ggaggtgtga caagaatttt
    23401 gtcacacctc ccttatttat tttgaaaatg agaatactat tatcaaaata gagaatatat
    23461 agaaaaattc tcattattca aacgtaaata atcagttatt ttgatttttt ttatatttta
    23521 ttagctaata attggtattt taaaagaaat tactgtagaa ttggattata attaaaaagg
    23581 agtgagaaaa tgataaaagt atatacttcg cctagctgta cttcctgtag aaaagcaaga
    23641 gcatggttgc aagcgaatca acttgaattt gaagagaaga atatttttgc cgaaccgtta
    23701 acagaaagtg agatcaaaaa gatcttggca gcgactgaag gaggagttca agatattatt
    23761 tccactcggt cgaaaattta cgaaaagctg ggcatagatt ttaacgaatt aactttaaag
    23821 caaatgatcg tcttattcaa agaatatcct tcattattga gacgacctat tttgattgat
    23881 gaaaaaagaa tactaatcgg atttaatgaa gatgagatcc ggtcatttgt ccctcgtgaa
    23941 attcgatgtg ttgccagaaa tctgatctat ttacaaaaca ataacatctt aaattcatag
    24001 ggagggagcc ttcgtggaag tgaaagtcta tggatcagcg cactgtgtaa caagtctgaa
    24061 ggcgaaacaa tggttagaac accatcaatt gccttatcaa tttgttgact tagaagaacg
    24121 cgatttaagt acagaagaag cagaagaatt atgcagtttt gaagaagtgc aagcagaaca
    24181 gctatttgcg acttggtctg aggcttttca caacattgcg attgaccttt cctgtgtagg
    24241 aaaaaaacaa ctgatttttt tatgcacaca acataccaat ctcctcagac gtcctttgat
    24301 tattatcgat gaagttctat ttattggata caatgagcag ttgatggaac agcttatctt
    24361 aaataaatag actttaactg ttttaatcaa gtcactgagc atttcataca gttgtaacag
    24421 tcgaacactt agcatcaagc gtgttatgtg ttcttttttt gactttattt ttctactata
    24481 gagacatgct caatttatgt ggtcaaaatt caaatctagg tggggatata gagttaaaaa
    24541 tatattgaca tgtgtaaatt tacatgatat attcatttct gttgttttaa gtagcaaagc
    24601 aataaaatag tattttaaaa aacatataaa atagttgttg acatgttaga aatgacatga
    24661 taagataact gagttgttaa aaaagaacca cttgtgaagc ttgattctat cgaaaaaaac
    24721 ttcaaaaaag ttcttgacaa ataacaaatg ataagttatg ataaatgagt tgctgtaaga
    24781 tttcgaaaaa cgaaatcaaa aaaactttta aaaaagagtt gacaattact tgtctctctg
    24841 atatgatata aaagttgcta cggcagccaa aaacgaatcg gg
//
LOCUS       DADQDV010000041        24541 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.041, whole genome shotgun sequence.
ACCESSION   DADQDV010000041 DADQDV010000000
VERSION     DADQDV010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 24541)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24541)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24541
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.041"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(27..602)
                     /locus_tag="J8S10_001722"
     CDS             complement(27..602)
                     /locus_tag="J8S10_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAZ9630308.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
     gene            complement(607..1581)
                     /locus_tag="J8S10_001723"
     CDS             complement(607..1581)
                     /locus_tag="J8S10_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine nucleosidase"
                     /protein_id="HAZ9630309.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIASALKVNPNIGKHMERFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEEAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFFRKFLTVLLNAQEETIMKDLERLKMG"
     regulatory      complement(1605..1649)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            1864..2832
                     /locus_tag="J8S10_001724"
     CDS             1864..2832
                     /locus_tag="J8S10_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAZ9630310.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMN"
     gene            2929..3222
                     /locus_tag="J8S10_001725"
     CDS             2929..3222
                     /locus_tag="J8S10_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HAZ9630311.1"
                     /translation="MRSAAYGNQRRKNRLALFNDEQQEIGEMTWSDAGPDIMIVDHTF
                     VDPAYRGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            3340..3576
                     /gene="secG"
                     /locus_tag="J8S10_001726"
     CDS             3340..3576
                     /gene="secG"
                     /locus_tag="J8S10_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HAZ9630312.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            3688..4434
                     /locus_tag="J8S10_001727"
     CDS             3688..4434
                     /locus_tag="J8S10_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAZ9630313.1"
                     /translation="MRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKADYTV
                     YAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFAVRA
                     LEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSLAEQ
                     QLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQWYPE
                     SGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            4437..6794
                     /gene="rnr"
                     /locus_tag="J8S10_001728"
     CDS             4437..6794
                     /gene="rnr"
                     /locus_tag="J8S10_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HAZ9630314.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKTRNGKSGKRE
                     GKQAGKRPERNGKKNKRYSDSKQTFGKKKGKKPFYKGVKKKKKKK"
     gene            6816..7280
                     /gene="smpB"
                     /locus_tag="J8S10_001729"
     CDS             6816..7280
                     /gene="smpB"
                     /locus_tag="J8S10_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HAZ9630315.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIIRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            7582..8301
                     /gene="atpB"
                     /locus_tag="J8S10_001730"
     CDS             7582..8301
                     /gene="atpB"
                     /locus_tag="J8S10_001730"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HAZ9630316.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            8354..8569
                     /gene="atpE"
                     /locus_tag="J8S10_001731"
     CDS             8354..8569
                     /gene="atpE"
                     /locus_tag="J8S10_001731"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HAZ9630317.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            8660..9184
                     /gene="atpF"
                     /locus_tag="J8S10_001732"
     CDS             8660..9184
                     /gene="atpF"
                     /locus_tag="J8S10_001732"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HAZ9630318.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            9171..9713
                     /locus_tag="J8S10_001733"
     CDS             9171..9713
                     /locus_tag="J8S10_001733"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HAZ9630319.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            9736..11292
                     /locus_tag="J8S10_001734"
     CDS             9736..11292
                     /locus_tag="J8S10_001734"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HAZ9630320.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGSNSST
                     EDKLKSIQNA"
     gene            11306..12208
                     /locus_tag="J8S10_001735"
     CDS             11306..12208
                     /locus_tag="J8S10_001735"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HAZ9630321.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMFQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            12231..13637
                     /gene="atpD"
                     /locus_tag="J8S10_001736"
     CDS             12231..13637
                     /gene="atpD"
                     /locus_tag="J8S10_001736"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HAZ9630322.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            13651..14073
                     /locus_tag="J8S10_001737"
     CDS             13651..14073
                     /locus_tag="J8S10_001737"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HAZ9630323.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
     gene            14542..14772
                     /locus_tag="J8S10_001738"
     CDS             14542..14772
                     /locus_tag="J8S10_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HAZ9630324.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            14869..16170
                     /gene="murA"
                     /locus_tag="J8S10_001739"
     CDS             14869..16170
                     /gene="murA"
                     /locus_tag="J8S10_001739"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HAZ9630325.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            16183..16359
                     /locus_tag="J8S10_001740"
     CDS             16183..16359
                     /locus_tag="J8S10_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HAZ9630326.1"
                     /translation="MSNQRYILLTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            16494..16790
                     /gene="yidD"
                     /locus_tag="J8S10_001741"
     CDS             16494..16790
                     /gene="yidD"
                     /locus_tag="J8S10_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HAZ9630327.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            16854..17321
                     /locus_tag="J8S10_001742"
     CDS             16854..17321
                     /locus_tag="J8S10_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAZ9630328.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASNQTRIIIRTGTTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            17406..18290
                     /locus_tag="J8S10_001743"
     CDS             17406..18290
                     /locus_tag="J8S10_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAZ9630329.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKTQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLD
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLIGAAANYLAVRQGEN"
     gene            18407..18640
                     /locus_tag="J8S10_001744"
     CDS             18407..18640
                     /locus_tag="J8S10_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HAZ9630330.1"
                     /translation="MSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYGP
                     KEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            18728..18808
                     /locus_tag="J8S10_001745"
     tRNA            18728..18808
                     /locus_tag="J8S10_001745"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:18762..18764,aa:Tyr,seq:gta)
     gene            18815..18886
                     /locus_tag="J8S10_001746"
     tRNA            18815..18886
                     /locus_tag="J8S10_001746"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:18847..18849,aa:Gln,seq:ttg)
     gene            19402..20109
                     /locus_tag="J8S10_001747"
     CDS             19402..20109
                     /locus_tag="J8S10_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAZ9630331.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRRDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(20168..20812)
                     /locus_tag="J8S10_001748"
     CDS             complement(20168..20812)
                     /locus_tag="J8S10_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HAZ9630332.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKNFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSANHFKESIIELLNGQVQFEEGSVSYHEQLITDHI"
     gene            20939..21226
                     /locus_tag="J8S10_001749"
     CDS             20939..21226
                     /locus_tag="J8S10_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630333.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            21334..21654
                     /locus_tag="J8S10_001750"
     CDS             21334..21654
                     /locus_tag="J8S10_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAZ9630334.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIA
                     LIGE"
     gene            21972..23048
                     /locus_tag="J8S10_001751"
     CDS             21972..23048
                     /locus_tag="J8S10_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAZ9630335.1"
                     /translation="MFDQPEAKPREVVFFWTGQLTEKQTEIAKRILCHSEKRHHLIWA
                     VTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNELFLRYRYVFPEEKITLLHGNTA
                     TAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYNGDAGLAHAVQTAIRSNGRFIY
                     LSATPDEKLLKEIKQTFELHKLALRFHRRLLPEPVLVFMNNWRQKCGNKKKINSLVRI
                     IQQLIKENRILLFCPSITMMHRLKITLQEAFPEYEITDVSSQDDQRAKKVQKMREAIY
                     EILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQIAGRADRKGPYTNSRVYFFYE
                     EKTSAIRKACQEIKEMNEEGKQML"
     gene            23045..23764
                     /locus_tag="J8S10_001752"
     CDS             23045..23764
                     /locus_tag="J8S10_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HAZ9630336.1"
                     /translation="MRCSCCGKDIIQNLTFSEIIGVSKSRLPQTCSVCRAQFHLLEAK
                     GCAGCQKPIHLKYEETKKKANTSFVYCNDCQEWKKKYPAYDFQHRAFFTYDEKMQAWI
                     NRYKFMGDIRLAGTFAYKWTQIKKDYPAYIYCPIPLSEKRWLERGFNQVSEMLKAAKI
                     PFQMLLKREQHLLAQAKNTRKERLEMPQPFELAVPLSKIQHKKILIIDDVYTTGQTLF
                     HAADCLQNAQPKIIRTISLAR"
     gene            23892..24443
                     /gene="raiA"
                     /locus_tag="J8S10_001753"
     CDS             23892..24443
                     /gene="raiA"
                     /locus_tag="J8S10_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HAZ9630337.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
BASE COUNT         8131 a         4281 c         5274 g         6855 t
ORIGIN      
        1 tattttgcta atccagctct gtttattcag cctatttttc tttttgaata tatcaagcgt
       61 tgtggcaaca tagtgatgac taatgaaaca acgacgatag acaacaaacg atcaaggtag
      121 tctgtacctg cctgtaccaa gatcacactt gttgtctgac ttaaacctaa cccatgtaat
      181 agctgaacga tcatactgga tcctgaggag gtgatcccgc caaataactg aacggtaatg
      241 atcgaagaaa cgatcgttcc aggtaccgac aaaatcaaag cgagtaataa cagtttcaag
      301 ctgtttttat ctttgccgag atatcttggc aaaatcaatc cagcaagcaa gcctgtgaga
      361 atttggattg gcgaataata cagagaaaaa atatctgtag tcactccact taaaataccg
      421 ctggacaatc ctgtcagcat tccaggtaca ggcccaagca atgcaccagc aaaaatcgtt
      481 ccgatagaat cgagatagat tggcaaacga agccataaag caatcgttcc tccaatataa
      541 ttgatcccaa tacacaaagc catcactgta agtacgcgag ttgccatttt gtttttattc
      601 attttgttag cccatcttta acctttccaa atctttcata atcgtttctt cttgtgcatt
      661 taaaagaacg gttaaaaact ttcggaaaaa aagacgagta tctacttttg tcataatttt
      721 actgttagca ggtttctgcc aaaattcata acgatcaacc aatgtttgtc cacgacttat
      781 tccttgagtt tccacagcag tgaagctttt gaaaccttca cagatggcct cctcgataaa
      841 ataagcaaca gctaacggat cattgatgac acatcctaaa attctttctt gtttccagtg
      901 gaagtcaaaa taaaaacgag tgatcgcttt tagatactct ccctcttcag gattcatttg
      961 acagcagtat tcgaggatag tcggtgtcaa gacgatttct cttgtcacat ctaacccaac
     1021 catttctatc gtttgtttga gattctcgaa tacataagaa gctgcttcag gatcacacca
     1081 gtaattgtat tcagcaactg gcgaacagtt accatggctt ttgtaagttc cacccatcga
     1141 gacaaaacgt tccatatgtt tcccaatatt tgggttgact ttcaaagcag aagcgatatt
     1201 ggtcaaagga cccaaagcaa tgactgatgt atttgtcttt tctttgaaat aatcagccaa
     1261 aaaatcaacg gcatggagag gttctgcctg ttttctcaag atcatcggga aatttgtttc
     1321 ccctaaacca tccataccat gagtgtcttg tgcactgatg aaaggttgct tcaaaggttt
     1381 ttccattcct tgataaacag gaatgtctaa acgatcacag cgttccaggc atttcagcac
     1441 attctgcgta cctatatctg cagggacatt cccacaaact acggtaatag caactacttc
     1501 gatatcaggg gatttgacag ctaatgataa agctaaagtg tcgtcgatcc ctggatcgca
     1561 atcaataatt acttttcgca ttatttccaa tctcctttct ttagagatac ttagtttttt
     1621 attctgggaa gtttccgaac cagtccaaga cgagcgtctt gattataatg cacgaaatta
     1681 gtatactggc ttttattgcg aatgtaaatg ctctcttaca agtaaatcta ttgaggagaa
     1741 ctttaagtaa atgatacaat gaaaaagaaa tggaatttac gtgtgccgaa aataaagaat
     1801 cctatggatc ggtacattgg ataatagata gattatagtt tggcagaaag cggcgggtgt
     1861 acaatggtta ttttttattt cattcttatt ctgataatta tagggatcag ttaccatttt
     1921 ctttcttatt tttatgcaaa gaaattagta agagcgggag tacagagagg atatgactgg
     1981 tatgaagaca ctggtcatcg tttgatggac cctgctgcag tcacgtcagt agaaaaaaaa
     2041 cgacaaaaat tagaagaaga gtgtgaaagc ttttgggagc agggaacacc caaaacaatc
     2101 aaaagttatg acgggttgaa actagctggt cagatgttca tccatccaaa taagcagaat
     2161 aaatgggtca tttgcgtaca tgattaccga agcacaggga aaagagacat gtctcatata
     2221 ggtaaaagat atgcagagaa aggattcaac gttcttgtac ctgatttacg tgcgcacgga
     2281 gaaagtgaag gagaaatcat cggaatggga tggctagatc ggctagattt aattgcctgg
     2341 atccaactca tcttagatga acagccgaat gcgtccatta ttttacacgg cggatcaatg
     2401 ggagcttcta cgatcatgat ggcaagtggt gaaaaacttc catcagcggt caaaggattt
     2461 attttagaca gcggatatgt ttctgtttat gcagaattcc gatatatgtt aagtaaaatc
     2521 actgtctttc ctaaaaaaat ggtcatgaga tatgcgaatc attatgccca gaaatacgcc
     2581 ggttactcct taaagcaagc atcagctacg agacagcttg gcagcaatca tctgccttta
     2641 ttagtcatcc atggtgaaag agatcatttt gtccctacag aagcagcgta cacgattcaa
     2701 aatgctacgg caggggataa agcactgctg cttgttccgg aagcagaaca cttggaagca
     2761 tcgatgaaag atccgaaaac ctattggaca gtgatttttt catttattga acaaagaata
     2821 acgatgaatt aattttctct tcttttttgt aagtaattcg aggataaata attgtttata
     2881 gatcaggaga ctgctaaaat aaggtaggaa taaaaaaata tcagttattt gaggagtgcg
     2941 gcatatggaa atcaaagaag aaaaaatcgt cttgctttat tcaatgatga acaacaagag
     3001 atcggagaaa tgacatggtc agatgcgggc ccagacatca tgatcgttga ccatacattt
     3061 gtagatccag catatcgtgg tcaaaagtta gctgaaaagc tagtgtatac tggagtagaa
     3121 ttagcaagac gagacgggaa aaagatcatt cctttatgcc cttatgcaaa aaaagagttt
     3181 gaaaagaaac cagaatatca agacgtctta cgtcagtcat aagaataaca gctgaaagtt
     3241 ttgaactttc agctgttatt ccatttatat agagttgtca cggactttta tctatgataa
     3301 agttaaagag acgatatctt ttgggaagga ggctgcgata tgtataattt aattttggga
     3361 atcgtgatcg ttttatcgat tgttatggtc attgcgatta tgatgcagcc aagcaagcaa
     3421 aatagtgcag cgagtgcatt taccggcggt gcggatcaac tattcggcaa acaaaaagct
     3481 cgcggctttg aagctgtcat gcagcgatca actgcagtta tgggagctat ctggatgatc
     3541 ttattatttg tcctagcata tttatcttcg aagtagttga ataagcctct cgcaaaacgg
     3601 cgggcggctt tttttattgc aaagagaacg cttaagaaga agttatgaaa gaaactatgg
     3661 taaaatgagg cgaaagaggt gagacgagtg agacaattac caaaacccct ttatgcaaaa
     3721 catggaaagc gagcggtttt gctgcttcac gcttactcag gaagtccaaa cgatgttcga
     3781 atgctcgcac gatttttgga aaaagcagat tatacagttt atgcgccgct ttttaaagga
     3841 cacggaacaa tggagccata tgatatcttg caagaaaaag cagaaagctg gtgggcagac
     3901 actaaaaaag ccatccattt tttacagtct gagcagtttt ctgatattgc cgtattagga
     3961 ttatcaatgg gcggcatctt tgctgtacga gcactagaag aagaatcagt gattggcggc
     4021 ggttttttct gttcgccttt gtctcctgta aaaacaaacg tgcctgaaaa ctttgaaaaa
     4081 tacgtacgtc aagtgctgaa gacagcaggt aaatcagaga aagaaatcaa tgaaaaagca
     4141 gttgcttacc gctcgttagc tgaacaacaa ttaatggata tacaagatca ggcagcaatc
     4201 gtagaaagta ggttgtcaga tatccaacag ccgatatttt tagctcaagc tgggaaagat
     4261 gaaatgatcg accctaatgg cgtatttgaa actgcacgca agttgagccg tcagcgagtg
     4321 acacttcaat ggtatcctga aagtggtcat gtgattacag ttggtacagc aagacgcgaa
     4381 ttagaaaaag acgtcttgga atttttagaa aaattacctt ggaatgagga ataaatatga
     4441 caaaagaaac gataaaagag aaaattctct ttttcatgga aagcagtcgc aaacgcagtt
     4501 tttctatgga agaaatcgct gaaggtttag ggttccaaaa aagcgatgat tttaaattac
     4561 tagtacaaac gattgctcaa atggaaagag aacagagtat agttttcaat aaaaaaggaa
     4621 aagtgaaact tcctttaaaa ccaatcctga tcgaaggaac atttcgagca aatgaacgag
     4681 gatttggatt tgtaacgatt gatcccgaag aagatgacat ctatatccca aaagaagcga
     4741 ctggttttgc aatggatgga gacaccgtag caatcgatat catgaagcga gcaaatacag
     4801 atatggatcg cggagcagag gggaaagtag tcgagattcg agaccgggcg actactcagt
     4861 tagcagggga attcgttgct tattcagaag aagaaataca agaaacagat ctttacggcg
     4921 ttgttatccc gaaagataga aagctcaacc aatttaaagt atatgcagca gcagagggag
     4981 ttcgtccagt tgacggaagt attgtgctga tcgaactgac ccattaccct gaaaaagggt
     5041 atgcgactag tttagaaggg ataatcaagc aagtgattgg tcataagaat gaccctggca
     5101 tggatatcct ctcaattgtc gtggctaatg gtatccctac gaaatttcct gatgatgtat
     5161 tgtctgaagc agatgaagtt ccagatcaaa tcagcgaaaa ggatataact ggacgtagag
     5221 atttaagaaa tcagctcatt gttacgattg atggagaaga tgcaaaagat ctagatgatg
     5281 cagttacggt taaaaaatta gataacggta attattttct tggagtacac attgcagatg
     5341 tttcttacta tgtgacacaa ggcagtcaat tggacagaga agcatatgaa agagggacaa
     5401 gtgtatattt gactgatcga gtaattccga tgatcccgca acgtttatcg aatggtatct
     5461 gttcactgaa tccccatgtt ccaaggctga ccatgagttg cgaaatggag attgatccaa
     5521 atggacaagt agtctctcat gatattttcc caagtgtgat ccaaacaaca gaacggatga
     5581 cctacacagc tgtcaatcaa atcttagaag atcaagacga agaaacgatg caacgctatg
     5641 ctcagctcgt acctatgttc caagaaatgg gtgaattgca ccgaatcctt gaaacgatgc
     5701 gaatcaaacg tggcgcgatt tcttttgagg atcgcgaagc gaaaatcctt gttgatgctg
     5761 aaggacaccc aaatgacatc cagctaagaa gcagaggaat tggtgaacgc ttgatcgaat
     5821 ctttcatgct tgcggccaat gaaacggtag ctgaacatta taataaatta aatctgccgt
     5881 ttatttaccg aatccatgaa cagccaaaag aagaaaaaat gcagcgcttc tttgattttg
     5941 cttcagcttt gggcattctg gtccgaggaa cgaaaggaac gatcacacca aaagatttac
     6001 agcatgtgat cgaaggagta gaagacaaac cagaagctgc agttatcaat actatgttgc
     6061 taagaagcat gcaacaagca cgctattcag aagacaattt tgggcattat ggcttagcgg
     6121 cagattacta cacacacttt acatctccta ttcgacgcta tcccgatcta atcgtccatc
     6181 gtctgatccg ttcttacagt gaagataaaa gtgaaagcaa tcaaagttcg tgggctgcgg
     6241 aacttcctga aattgcagat catagttcta agatggaacg tcgtgcagta gaaacagaac
     6301 gtgaagtaga ttccatgaag aaagcagaat tcatgatgga caaagtggga gaagaattcg
     6361 atgggatcat cagctctgtt gtgaaattcg gcctgtttat cgaactgccg aatacagtag
     6421 agggattgat ccatatcaat gaattgaaac aggactactt ccattttgtt gaaaatcatt
     6481 tagctcttgt aggtgaaaga actggtctga cttttaaaat cggacagaaa gtgcgagtaa
     6541 aagtagtcaa agctgatcca gatgaacgag cagtagattt tgaacttgtt tccgcagaag
     6601 aggttacagc gttggaacgg ccaaaaacac gaaatggaaa atcaggaaaa cgcgaaggaa
     6661 aacaagcagg aaaacgccca gaaagaaatg gcaagaagaa caaacgatat agcgatagta
     6721 agcaaacgtt cggtaagaaa aaagggaaga agccatttta caaaggtgtt aaaaagaaga
     6781 aaaagaaaaa ataaaatgag ttggaggaaa cagctatgcc aaaaggcgag ggaaaattaa
     6841 ttgcacaaaa caagaaagct cgccatgatt attcgatcat cgacacgatg gaagcaggga
     6901 tggtcttgca aggaaccgag atcaagtcga tacgaaacag ccggatcaat ctaaaagatg
     6961 gatttattcg cgtccgcaac ggagaagctt tcttgcataa tgttcatatc agtccttatg
     7021 aacaaggaaa tatttttaat catgatccgt tgcgcacgag aaagttatta ttacacaaaa
     7081 aacaaatcat ccggcttgaa aatgaattga aaaatactgg aatcactgtt gttcctttaa
     7141 aagtctatat tcgtaacggc tatgccaagg tattgattgg tctggcgaaa gggaaaaaat
     7201 cttatgataa acgggaagat ttgaaacgaa aagatatcga tcgacaaatt gatcgaacat
     7261 taaaaaattt ctctagataa tttcattatc ctttttcgca tattcggtgc ttttgctttt
     7321 acttaatgat aaaatttgtt agcatttaat ctgataaaac atgattatca taggtttttt
     7381 cttagatcag gagcaccgtg tataaagaaa aattcgcttc gtttttgact gaaataaaaa
     7441 agtgtctaat tttcatgaaa atgttttgaa ttttctgttt catggtggta tgataccgtg
     7501 tggttagaaa ccgattggaa aaaaccagat acgcacatga attgatttta tgtgaatttc
     7561 ggggaaaaga ggtgaaatgg attggatgaa cgctcgctaa cgttccacat tggaccaatt
     7621 tggtttgatg gtacagtttg tataatggtg ttactgacct gtttgattgt tttcttctta
     7681 gcttactttt ttacaagaaa tcttaagttg aaaccaacag gcaaacaaaa tgcgatagaa
     7741 tgggtcattg attttagtcg aggaatcgta acagataatc tgcctagaaa agaattgagc
     7801 aatttccatt tgttggcatt tacattgttt ttatttgttt ttgttgcaaa caacatcggt
     7861 ttagtaacaa aaatcgtttt acctaacgaa acaacacttt ggaaaagccc gacagcagac
     7921 ccgtttgtta ctttaacttt ggcatttata atgatcttac ttactcactt attcggggtg
     7981 aaaaagttag gcttcaaagg atatttcgta aattcgttct tgaaacccta tagttttatg
     8041 tttccgatga aactgattga agaatttaca aacttattaa cacttgcttt acgtctttat
     8101 gggaatattt atgcggggga agttttgcta accttgattg caaaaatgat gacaagctta
     8161 ggctggttct cattaccatt agcaattcca ttagagatgg tctggatcgc gttctccttg
     8221 tttattggga gcatccaagc atttgtcttt gtcactttgt caatggttta tatgagccat
     8281 aagattgaag tagaagaata atactcggtt aaaaaacaaa ctactattta tctattttag
     8341 gaggaaaaca attatgaatt atatcgcagc agcaatcgca atcatgggag cagcaatcgg
     8401 agccggttat ggtaacggtc aagttatctc taaaacaatc gaatcaatgg ctcgccaacc
     8461 tgaaatgtct ggtcaattcc gtacaacaat gtttatcggg gtagctctag ttgaagctgt
     8521 tcctatctta ggggtagtta tcgccttgat tctagttttt gccgtttaat tgaatcagta
     8581 ttaaggcaga aacaacatcg tttgttactg cttttttaca tggaaactag aaatactcca
     8641 aagaaaggaa ggctcgccta tgctgaatca attggcaatt gcagaagttg gcaatgcgat
     8701 gttaggtaat atcatcgttg tcagcggctc atttttgata ctactggctc tcttgaagca
     8761 ctttgcttgg ggaccaatca gcgatatttt gaaaaaacgt gaagacaaga tcgccaatga
     8821 tttagattct gcagaacaat ctcgcatcaa ctcagcgaaa atggaacaag aacgcgaaca
     8881 acaattgtta gcctctcgtt ctgatgcagc tgatatcatc aaaaatgcga aagaaagtgg
     8941 agaattaagc cgccaaaata ttttgaagga tgctcaagaa gaagcagctc gtctaaaaag
     9001 caaagcccaa gctgatatca ctgtagaacg tgattcagcg ctgaactctg taaaagacga
     9061 cgttgcagaa ctctctcttc aaatcgcgga aaaaatcttg aacaaagaat tatctccaga
     9121 aatgcatgaa tcattaatca atcaatacat tgaaggtcta ggttcttcaa atgaaactag
     9181 ataaatatac agtaggaaga cgttacggga aagctttatt tgaactggcg atcgattcaa
     9241 atcaagcaga agaaatctat caagatctcg taagtttacg tcaaatctat gaacaagtac
     9301 ctggattagg gaatatgtta agtgatgttc gtctagaacc tcatgaaaaa cgagaaatca
     9361 tggacaagct tgtcagcggt tatgatggga tcgttaaaaa ctttttagaa gttgtttatg
     9421 agtataaccg aatggatgac cttttgttca tgatcgaaga atatgaacgt cgatatgatg
     9481 aacatcaagg gttactattg ggaagtgtca caacagcagt cccactttca gacgaacaac
     9541 gaatacaatt agaaaagaat gttgcaaaaa caatggacta tcaatcagtt gaattaaaac
     9601 aaatcgttga ttcttctatt attggtggcg cgattgttga agccaaccat cgagtaatcg
     9661 acggaagcat tcgcacgcaa ttagaaaaaa tgcgtaatca attaaacaga tagtacaaag
     9721 aggtaggtga atcgaatggc catcaaagca gaagaaatta gtgccttgat taaagaacaa
     9781 attgaaaatt atcaaaacgt gctttcagtc gaagaaatcg gtaccgtaac ttatgtaggt
     9841 gacgggatcg ctcgtgcaca tggtttagaa aacgcgatga gtggtgagtt gcttgaattt
     9901 tcaaacggct catacggaat ggcgcaaaac ttagagtcaa atgatgtagg tatcattatc
     9961 cttggcgatt tcgagtccat tcgtgaagga gataaagtaa aacgaacagg taagatcatg
    10021 gaagttccag ttggagaggc cttgatcggt cgggtagtca atccgctagg tcaaccaatc
    10081 gacggactag gtgaaatcgt tactgacaaa gctcgtccag tagaagcgat ggcaccaggt
    10141 gttatgcaac gtaaatctgt taacgaacca atgcaaacag ggctaaaagc gatcgacgcc
    10201 cttgtgccaa tcggacgcgg acaacgtgaa ttagtcatcg gtgaccgtaa aacagggaaa
    10261 acttctattg cgatcgatac gatcatcaac caaaaaggtc aagatatgat ctgtatctat
    10321 gtagcaatcg gacaaaaaga ttctacagtt cgtacacaag ttgaaacatt gaaaaaatat
    10381 ggcgcaatgg attacacaat cgttgtgaat gccggtgcgt ctcaaccagc accattgctt
    10441 tatatcgcac catatgctgg tactgcaatg ggtgaagaat tcatgtacaa cggtaaacat
    10501 gtattgatca tttttgatga tctttcaaaa caagctgttg cttatcgtga actttccttg
    10561 ctacttcgcc gtccaccagg tcgtgaagct tatcctgggg atgttttcta cttgcactca
    10621 cgtttattag aacgtgcagc aaaattaagt gatgatttag gtggcggttc aatgactgcc
    10681 ttaccatttg ttgaaacaca agctggagat atctctgctt atatcccaac aaacgttatt
    10741 tcgatcactg atggacaaat cttcttagaa agcgacttgt tctacgcagg tactcgtcca
    10801 gcggttgatg ccggactatc tgtatctcgt gtaggaggtt ctgcgcaaat caaagcaatg
    10861 aaaaaagttg ctgggacttt acgcctagac ttagcaagtt accgtgaatt agaagcattt
    10921 acacaattcg gttctgactt ggatgcagca acacaagcaa aactaaatcg tggacgccgt
    10981 acagtagaaa tcttgaaaca aaaattgcat gcaccgctag ctgttgaaaa acaagtagtg
    11041 attttgtatg ctttgacaca tggattctta gatagtatcc ctgtagacag tattttagac
    11101 ttcgaacatg aattattcga atatctggat accaatcatt cagatatctt tgaaacaatc
    11161 cgtacaacaa aagatcttcc agaagaagaa gcgttgaaca gtgcgattca ggaatataaa
    11221 gacatgttct tagctacaaa aggaagtaat tcctctacag aagataaatt gaaatccatt
    11281 caaaatgcat agtgaggtga gatgaatggg tgcttcatta aatgaaatca agacacgtat
    11341 cgcttcaacg aaaaaaacga gccaaatcac gcgggcaatg cagatggtgt ctgcttctaa
    11401 gttgacaaaa tctgaagctt cttcacagaa gtttcaggtt tatgcaacaa aagtaagaga
    11461 aatcgttacg catttgactg ctactcagtt aaatgatatt gcctcagaaa atcctagagg
    11521 ggatatcaat tacaacagca tgctgctcag ccgtcctgtg aagaaaactg gttatatcgt
    11581 catcactgca gatggcggtt tagtcggtgg atataacagc tcgatattga aacaaacgat
    11641 gtctatttta gaagaagacc accaatcacc cgatgattac gtgatgatcg caattggcgg
    11701 aactggtgca gacttcttta aagcacgcgg tatcaatcta gcatatgagc tgcgcaatct
    11761 atctgatcag ccaagctttg atgaagtccg caaaattgta aatatggcaa caactatgtt
    11821 ccaaaacgaa gtattcgatg aattatacgt atgttataac catcatatca attcgctaac
    11881 tagtcagttt cgtgtagaaa aaatgctgcc aatctcagac ttagatccag aagaagcaac
    11941 gactttcgaa caagaatata tttttgaacc ttcaaaagaa gaaatcttgt ctcagttatt
    12001 gcctcagtat gctgaaagtt tgatctacgg tgcgatcgtt gacgccaaaa cagcagaaca
    12061 tgctgctggt atgacagcaa tgaaaacagc aactgataat gctgctaata tcattgatga
    12121 gctgacggtt tcttataacc gtgcaagaca aggggctatt acccaagaaa ttaccgaaat
    12181 tgttgccgga gcttcggcac tagaatagta ttgagattgg aggaaaaaag atgagttcag
    12241 gcaagattgt tcaagtaatc ggtcccgttg tcgacgtgga attttcttta gaccaatcct
    12301 taccagatat caacaacgca ttagttgttt ataaaaatga cgaaaataaa tcaaaagttg
    12361 ttcttgaagc agcgttagaa ttaggggacg gagtgatccg gaccattgcg atggaatcaa
    12421 cagatggttt acaaagagga atggaagtca ttgatacagg caaagcaatc tctgttcctg
    12481 taggtaaaga aacattaggt cgcgtattca acgtactagg agatacgatc gatttagaaa
    12541 cacctttccc agaagatgcg gaaagaagcg aaattcataa aaaagcacca gcctttgacg
    12601 aattaagtac aagtacagaa attttggaaa cagggatcaa agttatcgat ttgcttgccc
    12661 catatttaaa aggtgggaaa gtcggactat tcggtggtgc cggtgttggt aaaaccgtac
    12721 tgatccaaga actgatccat aatatcgccc aagaacatgg tggtatttct gtatttaccg
    12781 gtgtaggtga acgtactcgt gaaggtaatg acttgtatta tgaaatgaaa gattcaggag
    12841 ttatcgaaaa aacagccatg gtgttcggac aaatgaacga accaccaggt gcacgtatgc
    12901 gtgttgcttt gactggtttg acgattgcgg aatatttccg tgatgtagaa ggtcaagatg
    12961 tactgttgtt tatcgacaac attttccgtt tcactcaagc tggatctgaa gtatcagcct
    13021 tgttaggacg gatgccttct gcggttggtt atcaaccaac attggcaaca gaaatgggtc
    13081 aattgcaaga acgtatcaca tctacgaaaa aaggttcgat cacatcgatc caagcaatct
    13141 atgtgccagc cgatgactac actgacccgg cgccggcaac agcattcgcc catttggatg
    13201 cgacaaccaa cttggaacgt aaattaacag aacaagggat ttatccagcg gtagatccat
    13261 tggcttcttc ttcaagtgct ttagcacctg aaatcgtggg agaagaacat tataaagtag
    13321 caacagaagt ccaacacgta ttgcaacgat atcgtgaatt acaagatatc attgctatct
    13381 taggtatgga tgaattatcc gatcaagaaa aagtgttagt ttctcgtgcc cgcagagtcc
    13441 aattcttctt gtcacaaaac tttaacgtgg ctgaacaatt tactggtctt ccaggttcat
    13501 atgtccctgt agaagaaaca gtgaaaggat tccgcgaaat cttggaaggc aaatacgatg
    13561 atcttcctga agaagctttc cgaagtgttg gccgaatcga agacgtcgta gaaaaagcga
    13621 aaacactagg ctactagaaa ggggtgcccc atggatcaat atttaacagt aaatgtggta
    13681 actcctgccg gtttggtcta tgatcaccat gcagctatcg tcgttgcacg tacgacagct
    13741 ggtgagcttg ggattttgcc taaacatgca ccaatcatcg ttccattgac gattgatgaa
    13801 gttcgtgtaa aacgaacaga ttcagatacc cacgtcgatt ggatcgctgt taatggcgga
    13861 atcatggaag ttcgtgataa tgttgtttca atcgttgctg atagtgcgga acgtgaacgt
    13921 gatatcgatg tatctcgtgc ggaacgtgca aaacaacgcg cagaacgcca aatcgaagaa
    13981 gcaaaagcaa aacaagatac gaacgaattg aaacgggcaa ctgttgcgtt gcaccgagca
    14041 atcaatcgta tcaaagtatc taagcactca taaaatgaga tgcggatgtt tatccgtgtt
    14101 taagaacagt aaaaagaggt tatgacagaa gtggtcagct tcaagacata agaaggaatt
    14161 tacgaaaatt gcttctcaaa tttttgtgaa atctcagctt atttttcgaa gaagctactt
    14221 ctggaacacc gtatatcaga ggttgtgaaa tcagcgtttt gtcctgagta ttagagaaac
    14281 aaatggaaaa tagttcctca tattttgccg ttttttgagc taataccgag ggtcagatga
    14341 ttgaacaccg tttatttgga ataagggact gcgacaagac ttttgtctca gtcccttttt
    14401 ttgcatattt ttagcattta tttcctaaaa aatgtaaggg gattcctata tttttaagta
    14461 tacttgtttt tccttttata cattttatgg tattatcatt ttattagtta ttataaaaca
    14521 atcgttagaa aggacgtcat tatgcaagta tacggaattg atgcggtgct tcgaatcgtg
    14581 agtcatttgg cgtttatcta cttagccttc tggtctttac gttcgttacg cattgaaact
    14641 tttttcagac caatgcataa tacgcaaatt agaatggcaa tcgtactttt ttcaattttt
    14701 ttagggtaca ctgcaagtaa ttttttctta gaggttatcg ctttatgccg aaatcttttc
    14761 gttagcctgt aaattttaaa aaaaggtact attttaaaag caaggatgtt ataatagaaa
    14821 agattttgag taagtgtatg ctcattggaa ttttttggag ggaacaacat ggaagagatc
    14881 atcgtaagag gtggcaatca attaaatgga acagtaagaa ttgaaggagc taaaaatgct
    14941 gttttgccta ttttagctgc tagtttgtta gcagaagaag gtattacgac attagacaac
    15001 gttccgattc tttctgatgt cttcactatg aatcaagtga ttcgtcactt aaacgtagat
    15061 gtagattttg atgaacaaaa gaatcaagta acaatcgacg cttcaagaca attagaaatc
    15121 gaagcgcctt atgagtatgt tagtcaaatg cgtgcttcaa tcgttgtgat gggtccgcta
    15181 cttgccagaa atggacatgc aaaagtagct atgcctggtg gatgtgcgat tggtaaacga
    15241 ccaatcgatt tgcatttaaa aggatttcaa gctttaggag caaaaattat tcaaaaaaac
    15301 ggctatatcg aagcaattgc ggatgaattg atcggtaaca cgatttattt agatttccct
    15361 agtgtaggtg ctactcaaaa tatcatgatg gctgccgtaa aagcaaaagg aacaaccatc
    15421 attgaaaacg tagctcgcga accagaaatc gttgatttag caaacatttt gaataaaatg
    15481 ggcgctcaag tctatggagc tggtactgaa acaatgcgta ttgaaggcgt ggatcattta
    15541 catgcagtca accactcaat cgtacaagat cgtatcgaag caggtacctt tatggttgct
    15601 gctgcaatga cacaaggcaa tgtgctgatt gcagatgcta tctctgaaca taaccgccca
    15661 ttgatttcta aattgatcga aatgggtgca gaaatcattg aagaagaagg cggagtccgt
    15721 gtcatcggac caaaacatat cttacctaca gatgtaaaaa cgatgcctca tcctggtttc
    15781 cctacagata tgcaagctca aatgacagct atccaattag ttgcagaagg tacaagtgtg
    15841 gtgactgaaa cagtgtttga aaatcgtttc caacatttag aagagatgcg ccgtatgaac
    15901 gctcatgtca aaatcgacgg aaatgtagca atcatggatg gaaaccatga attgcaaggt
    15961 gcagaagtat atgcaacaga cttgcgggca gcagcagcat tagttttagc tggcttgaaa
    16021 gcaaatggaa tcacacgtgt gcgtaacttg aattatctag accgtggata ttataatttc
    16081 catatcaaac tacagcaatt aggtgcagac gtcgaacgtg tagacatgga tcaaacttct
    16141 gctgaaaaaa cagcacaaac gattgcttaa ggaagtggct gaatgagtaa ccaacgatat
    16201 atcttattaa ctttgataaa gattttagtg gtgatcttat tgcttatcct tctttttgtg
    16261 gccggaacga tgatcggata tggtgtcatc ggtggcggca atccatttaa agtattccag
    16321 ccaagtttgt ggattcatat tcgagacttt tttcattgat aaataagaat cacagtggtt
    16381 ctagtcgata tgaagtgagc catgaagcag aacatgataa aagaaaacag aagggaacgt
    16441 tgacgttagt cgcgatccct ttttttagta aaagaaaaga aggaatctaa ttgatgaaga
    16501 agatattgat ttatttagtt agaggatatc agcgctttat ttcgcctgca tttccaccta
    16561 gctgccgtta ttacccaacc tgttccaatt atatgataaa agcaattcaa acccatggtg
    16621 cgctaaaagg gacggtaatg gggactgcac ggatcttacg ctgtcatcct tttgtcaaag
    16681 gcggtatcga ttatgtacca ttgacattcc gattaacgcg aaataagaaa gataaaaaag
    16741 aaccagatta taaaaaggtt gtgaaaaata cgggtagcac tgagcgataa agaaaaagag
    16801 gaaatttatt gtcaaagtaa caactccgca actacttata tgggggacaa aaaatgatcg
    16861 aagaactaaa caagaaagat ttaccatggt ccttgttatt agatgcagat cctgataaag
    16921 aaaaagttca agtatatgtt tccagaggga gtggctggat atggaaagaa aaagaaaaaa
    16981 caataggtgt actgatctat gtggcaaggg aaaaagaata cgaaatcgtc aatgtagcag
    17041 taaccccaac gtatcaagga aaggggattg gcggaaaatt acttgagaca gcttttcaga
    17101 agctttcaca gctagcttca aaccaaactc ggatcattat acgtactggc actactagta
    17161 gcgctgcgtt acacctctat caaaaaatgg gctatgtgga gattggtcga gtcaaagact
    17221 attttatcca tcattactct gagcccattt ttgaaaatgg agatcaatta agggatcaag
    17281 tgattttagc aattcactta cctaaaaata gctttaacta ataaactttc aattcgagaa
    17341 aatgctttca aatgctaaat agatacatta caatagcttt agcaaacaaa aaggagaata
    17401 tttttatggg aatattagtt tttgattttg gtggatcggc tgtcaaatat ggttgttggg
    17461 atggcaaaga gattaaaggt aagggacaat ttgcaacgcc tgaatcttgg gaagaaatga
    17521 aaacgcaatt atttcaagtt tataaaaaaa tactcgtttc ttttgaagtc gaaggaattg
    17581 gaatcagctc tcctggagta gtgaataatg agaaacaggt gattgaggga atcagtgcga
    17641 ttccttatat tcatggattt aatattttcc gagatttgga aactctgttt caactcccag
    17701 taacgattga aaatgacgcc aactgtgccg gaatggctga attttatgaa ggtgctgccc
    17761 gtgattatca agatgttgct tttgttgtgg caggaactgg gattggcggg gcgttgttca
    17821 cgaaaggaca aataaataaa ggggcacatc tttacggtgg agaatttggg ttgatgttct
    17881 tagatggcga taagacattc agtaaacttg gtacagcggt acagatggct tggcgttatt
    17941 gtgaacgcaa aggtctcgat aaaaatgctt ataccggaaa agatgtcttt gaattagcag
    18001 aaactggaga tgcaatagca aaagaagaag ttgagagttt ttatacgtat cttacaaagg
    18061 gattattcag tattcaattt tcgtttgatc cagaagtgat cgtattaggc ggcggggttt
    18121 ctgcaaaaga agggctcatt gatgagatca aaagccgaat gaagaagctg acagaacaat
    18181 tcgatctgca tgatttcgaa ccgcagattt tattatgtga gtacagaaac gatgctaatc
    18241 ttataggtgc agcagcaaac tatctcgctg tacgtcaagg agagaattaa gagctttaga
    18301 gaaggtgcag cttgcataaa agaagagaat gaaatgaata ggagattttt acctaaggaa
    18361 tgttttattt gctgcagtat gataaaatat ctgagaggtg aaaatgatgt caaaaaaaaa
    18421 taaagatatt gaagtgcgta tagaagaagt gaaaaaagat atcaaaggta agaattatga
    18481 agtcactcag ttatttatag ggaaaaaaat gattggtgag atcttagcct atgggccaaa
    18541 agaatatgaa attttctttg gtgaagaaga ttttggaaaa gaaaaaagtc ttgaaaatgc
    18601 gatagaaaca gtgattcgac actggaatct gcacgaataa aaaaatatca aaaaaacttt
    18661 caataaaggg ttgcaaaaat ctggaaaatt aggtattata actaagtcag gttgatacaa
    18721 acctttcgga ggagtagcga agtggctaaa cgcgacggac tgtaaatccg ttccttaggg
    18781 ttcagtggtt cgaatccact ctcctccatt tcattggggt atagccaagc ggtaaggcaa
    18841 gggactttga ctccctcatg cgttggttcg aatccagcta ccccagtata ccacaatcgt
    18901 aagctctcgt tagttcgaga gctctttttt tttgctttgc taccttgttc cttgaagatt
    18961 ctgctgaatt aagatagagt taagttaact acaagaattg gagggatcca catgaaatgg
    19021 aaagaaaaag tagacgaagc agctgaaaag ttatatgatt tggtcaaatc agaaaaatac
    19081 aatattgaag tgaatattcc gaaaaaaggc ggaaaagcgg tccaggtaaa atcaaaacgc
    19141 ccaacgaatc atacaaaaaa atggatggct aaaaaccgct aataataaca aaagatccat
    19201 aagtcggcat tttcatcgat tttagggtct tttgttattt tctaggttga acatatctaa
    19261 aaaattgttt ctgacaatag gagtagggag aacgatgtgt gtctaaatcc tctgttgatg
    19321 gatagaaacc tttatctttt tcagttgtga atcaggtata taccagttat aatagaagaa
    19381 acgaaaggac gggtgtacgt tatgtcgaat caattacctg tatatataca gattcatgac
    19441 caattaaaaa atgaaatcga acaaggtata tggaaagtcg gagaccgtct tccttcagaa
    19501 agagaattag cagtgaaatt caatgtcagc cgtatgacgt tgagacaagc aattcaaaac
    19561 ttggcagatg aaggaatctt agaaagaaag atcggttcgg gtacgtatgt tgcgcgagaa
    19621 aaagtacaag aaaaaatgtc tggtgcaaca agttttacag aaattatgga atcacaaaat
    19681 cgagtaccgt ctagtcggac aatctcttat ttcttgactt cgccaagctc aagtgaaatg
    19741 gaaaaactaa acttgagtaa agatgacacg atcttgcgaa tggaacgtat tcgtttcgca
    19801 gatgatgtcc ctatttgttt tgaagttgcc agtgttccac aaaagctgat cgatggctac
    19861 agcaaagcag agattactga atcgttgtat cgcacgctag aagaaaaagg cgggaaaaag
    19921 atcggtccag cgaatcaaac gattactgct gtgttggctt ctgagaaaat tgctgactat
    19981 ttagaggtaa aacgaagaga tgcagttctt cgtttgcgcc agatttctta ttttgaagac
    20041 ggtacgccgt ttgagtatgt gcgtacgcaa tacgtaggaa atcgttttga gttttatttg
    20101 gaaaaataaa aaacaggtga tccctgattc cttattagaa ataaaagaga atcagaatca
    20161 cctgttttta tatatgatca gttatcagtt gctcgtgata agaaacagaa ccctcttcaa
    20221 attggacttg tccgttcagc agctcaatga tggattcttt aaagtggtta gcactttttt
    20281 catctacagc acagatgacg ctaacttgat cagtatattg gatttctttt ataaaaaaat
    20341 gttggagttc aagataattc tgtaattttc ctagttgcgg atacgtgatc atcacagaga
    20401 tctcctgttg caaggtacct tctacgattc caatgtcaga caatgcttga gagaccgcat
    20461 gagtgtatgc tcgtattaat ccgcctgtgc cgagtttcgt tcctccaaaa tatcgagtga
    20521 ctactgcagc tacattgatc agttgatttt ttttgaggac ttccaacatc ggtacgcccg
    20581 ccgttccact tggttctcca tcatcgctgc ttcgctggat ttcatttttt tctccaatga
    20641 tgaaggcgct gcagttatgg ttcgctttcc aatgttcttt ttttatttct tgaatgaaat
    20701 tttttgcttg gtcctctgat tctattcgtc taagagaaca gataaagcgt gattttttga
    20761 tctcaatctc actttgtcca ttttctttta ttgtacgata gcgctcgatc atcttgtcac
    20821 ctcttttttt cattttcttt attcagtata aataaagttc taggttgttt caacactgta
    20881 acggttgcgc aattgctgta gtatgcgata ataaagacaa aggcaggtgg atctggggat
    20941 gcaggaacga atgaaaaagt acgatgcaat tacgcattat ttgaagaaca atggcggctc
    21001 tcaagtaacg ttgaccttta cccaatttga cgaactgctg tttcccagta acggacttcc
    21061 caaaacagca agggaaagta cagattggtg ggcaaatgat tataaacacc ctgaaaaagg
    21121 tgcctatggc tggataaatg caggctatga agtagttgtc atcaatttgg acaaagaata
    21181 tgtcgtgttc aataaattag tgaaatctag ttggctattt gattaaataa accgcgttta
    21241 gaaaacgttg acaaatttct ttctttttat ataataaagt aacagacgcg aagaaaacgt
    21301 ttgcgtagtt tgttttaaaa aggagagaaa aatatggcta aaaaaacaat catgcttgta
    21361 tgttcggctg gtatgagcac aagtttacta gtaacaaaaa tgcaaaaagc tgctgaagca
    21421 aaaggaatcg actctgatat tttcgctgtg tccgcttctg acgcagataa caatcttgca
    21481 aataaagacg tggatgtgtt gttattaggc ccacaagttc gctttatgaa agctgatttt
    21541 gagaaacgtc tggaaccaaa aggcattcct ttagatgtca tcaatatggc tgattatggt
    21601 atgatgaatg gcgaaaaagt gttagatcaa gcaatcgcgc tcataggtga ataaatagaa
    21661 cagtataact atcgaacaag cgatccaaaa aatagatcgc ttgttttttc gtatattttt
    21721 ttagggcgaa taatatgaat catttttggg gtagaaggct tctgacgaga gatattaaag
    21781 caatagactg tgaggaggta aatttaccaa attatgagaa gatcgcagca gtggaacgtt
    21841 tgggcaactg gattctttgt catcgctgtg gaatgaggac gtccgtcatt gttggacagc
    21901 ttgcagatta cggttatttt tgtacacatt gtctatattt agggtgatgc gacactcaac
    21961 aagatttata tttgtttgat cagcctgaag caaaacctcg agaagtcgtc tttttttgga
    22021 caggacagct tactgaaaaa caaacggaaa tcgcaaagag aatactttgc cattcagaaa
    22081 aaagacatca tcttatttgg gctgtaacag gtgcagggaa aacagagatg ctttatccta
    22141 ttttagtgga aactttaaaa gctggaggaa gagtagcgat ttgtacaccg cgagtcgatg
    22201 tttgtaatga attgttttta cgctatcgtt atgtttttcc agaagaaaaa atcacgttgc
    22261 tccatgggaa tacagcaacg gcttatacct ttacttcttt tgttatctgt acgattcatc
    22321 agctataccg tttttatcgg tcctttgatt taatagtgat cgatgagatc gatgcgtttc
    22381 cttataacgg ggatgctggg ctagctcacg ctgtgcaaac agcaatcaga tcaaacggcc
    22441 gattcatcta cttaagtgcc acgcctgatg agaagttact aaaggaaatc aagcagacat
    22501 ttgagctcca caaacttgcc ttgcgctttc atcggcgctt gcttcctgaa cccgtgcttg
    22561 ttttcatgaa taattggcga caaaaatgtg gaaacaaaaa gaaaatcaac tctttggtgc
    22621 ggatcattca gcaactaatc aaagaaaacc gtatcctttt attttgtcca agtattacga
    22681 tgatgcatcg tttaaaaatc acactgcaag aagcttttcc agaatatgag ataacagatg
    22741 tttcttcaca agacgatcaa cgggcaaaga aagttcagaa aatgcgagaa gcaatatacg
    22801 agatactgtt aaccacaatg atcctagaaa gaggagtcac atttgaaaga atctctgtca
    22861 tcgttttagg agcagatcat ccagttttta ctaaatcctc tttggtgcaa atcgcaggaa
    22921 gagctgatcg taaaggtcct tatacgaaca gtcgagtcta ttttttctat gaagaaaaaa
    22981 cttcagctat tcgaaaagcc tgtcaggaaa tcaaagaaat gaacgaagaa gggaagcaga
    23041 tgctgtgaga tgtagttgct gcggtaaaga catcattcaa aatttaacat tcagcgagat
    23101 catcggagtg tcgaaatcta gacttcctca gacatgttca gtttgccgcg cacaattcca
    23161 tttattagaa gcaaaaggtt gtgcaggttg tcaaaaacca atccatttga aatacgagga
    23221 gacgaaaaag aaagcaaata ctagtttcgt ttactgcaac gactgtcaag aatggaagaa
    23281 gaaatatcct gcatatgatt ttcaacaccg cgcctttttt acgtacgatg aaaagatgca
    23341 ggcttggatc aatcggtaca agtttatggg agatatccga ttagcaggga cttttgcata
    23401 taaatggact cagataaaaa aagattaccc ggcatatatt tattgtccaa tacctttatc
    23461 tgaaaaaagg tggctagaaa gaggattcaa tcaagtaagc gagatgttga aagcagcaaa
    23521 aattcctttt cagatgctgc tcaaaagaga gcaacatctg cttgctcaag caaaaaacac
    23581 gcgaaaggaa agattggaga tgcctcagcc ttttgagctt gccgtacctc tttctaagat
    23641 acaacataaa aaaatattga ttattgacga tgtctataca acaggacaga cgctttttca
    23701 tgcagcagat tgcttgcaga acgcacagcc gaaaatcatc cgaaccattt ctttggcaag
    23761 atgaatcaga tgtggaaatt tgatagcgat ttaatttgca aataacctag agttcgatat
    23821 aatagaatta agaagaggga aagagtggtc cttctccttc ttgattgtgg tagacgaaag
    23881 gggtaatttt tatgtttaga tataatgtac gcggcgaaaa tatcgaagta actgaagcga
    23941 ttcgcgacta cgttgagaaa aaagtaggca aactagaacg ctatttcagt gacgcacccg
    24001 atgcaacggc gcatgtgaac ttaaaagttt atacagaaaa aacagcaaaa gtggaagtaa
    24061 cgatcccatt accttatctt gtattacgtg ccgaagaaac ttctccagat ttatacgcaa
    24121 gtatcgattt ggttgttgac aaattggaac gccaaatccg caaattcaaa acaaaaatta
    24181 atcgtaaatc ccgtgaaacg ggcatgaata ctgcagatgc tgctgcttta ttcaatgaag
    24241 aggacgaaaa cgaaaatgat tctgaattag atatcgtacg tacgaaacgc ctttcattga
    24301 aaccaatgga tagtgaagaa gcagtcttac aaatgaacat gctgggacat aacttcttta
    24361 tttttgaaga tgcagaaaca aatggtacaa gtatcgttta ccgccgtaaa gatggaaaat
    24421 acggactgat tgaaacagac tgatcagcct tacttaaata acaacgaaaa cttgcagcag
    24481 ctactgacag ctgccgcaag tttttttgag tttcctcctc ttttagatga aatatgaata
    24541 a
//
LOCUS       DADQDV010000042        23679 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.042, whole genome shotgun sequence.
ACCESSION   DADQDV010000042 DADQDV010000000
VERSION     DADQDV010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 23679)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23679)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23679
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.042"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(54..788)
                     /locus_tag="J8S10_001754"
     CDS             complement(54..788)
                     /locus_tag="J8S10_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HAZ9630338.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1115..1525
                     /locus_tag="J8S10_001755"
     CDS             1115..1525
                     /locus_tag="J8S10_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HAZ9630339.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1518..2219
                     /locus_tag="J8S10_001756"
     CDS             1518..2219
                     /locus_tag="J8S10_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HAZ9630340.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2219..3805
                     /locus_tag="J8S10_001757"
     CDS             2219..3805
                     /locus_tag="J8S10_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAZ9630341.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3824..4045
                     /locus_tag="J8S10_001758"
     CDS             3824..4045
                     /locus_tag="J8S10_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HAZ9630342.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4042..4803
                     /locus_tag="J8S10_001759"
     CDS             4042..4803
                     /locus_tag="J8S10_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HAZ9630343.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5183..5692
                     /locus_tag="J8S10_001760"
     CDS             5183..5692
                     /locus_tag="J8S10_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HAZ9630344.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5767..6306)
                     /locus_tag="J8S10_001761"
     CDS             complement(5767..6306)
                     /locus_tag="J8S10_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HAZ9630345.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6446..7057)
                     /gene="rpsD"
                     /locus_tag="J8S10_001762"
     CDS             complement(6446..7057)
                     /gene="rpsD"
                     /locus_tag="J8S10_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HAZ9630346.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7373..8170
                     /locus_tag="J8S10_001763"
     CDS             7373..8170
                     /locus_tag="J8S10_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate-nitrite transporter"
                     /protein_id="HAZ9630347.1"
                     /translation="MNPVSPLFEKIDASIEKKANLFENSFSRYAVRAVLACLFLTLGT
                     AVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAELGTSNMLYMTVGVFRQRLA
                     LSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNFMLESIAVKLAKPSATILV
                     EGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLGYEHVIANFPAFTLTYFAS
                     HGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQSKSSYVD"
     gene            8198..8833
                     /locus_tag="J8S10_001764"
     CDS             8198..8833
                     /locus_tag="J8S10_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HAZ9630348.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8853..9626
                     /locus_tag="J8S10_001765"
     CDS             8853..9626
                     /locus_tag="J8S10_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAZ9630349.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10034..10831
                     /locus_tag="J8S10_001766"
     CDS             10034..10831
                     /locus_tag="J8S10_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HAZ9630350.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10809..11222
                     /locus_tag="J8S10_001767"
     CDS             10809..11222
                     /locus_tag="J8S10_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630351.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11206..13851
                     /gene="mutS"
                     /locus_tag="J8S10_001768"
     CDS             11206..13851
                     /gene="mutS"
                     /locus_tag="J8S10_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HAZ9630352.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13869..15977
                     /gene="mutL"
                     /locus_tag="J8S10_001769"
     CDS             13869..15977
                     /gene="mutL"
                     /locus_tag="J8S10_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HAZ9630353.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRQTGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            15999..16559
                     /locus_tag="J8S10_001770"
     CDS             15999..16559
                     /locus_tag="J8S10_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HAZ9630354.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16644..18632)
                     /gene="treP"
                     /locus_tag="J8S10_001771"
     CDS             complement(16644..18632)
                     /gene="treP"
                     /locus_tag="J8S10_001771"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HAZ9630355.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18855..19568
                     /gene="treR"
                     /locus_tag="J8S10_001772"
     CDS             18855..19568
                     /gene="treR"
                     /locus_tag="J8S10_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HAZ9630356.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19645..20091
                     /gene="msrB"
                     /locus_tag="J8S10_001773"
     CDS             19645..20091
                     /gene="msrB"
                     /locus_tag="J8S10_001773"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HAZ9630357.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20261..20863
                     /gene="ruvA"
                     /locus_tag="J8S10_001774"
     CDS             20261..20863
                     /gene="ruvA"
                     /locus_tag="J8S10_001774"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HAZ9630358.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20876..21877
                     /gene="ruvB"
                     /locus_tag="J8S10_001775"
     CDS             20876..21877
                     /gene="ruvB"
                     /locus_tag="J8S10_001775"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HAZ9630359.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21906..22484
                     /locus_tag="J8S10_001776"
     CDS             21906..22484
                     /locus_tag="J8S10_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HAZ9630360.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22536..23018
                     /locus_tag="J8S10_001777"
     CDS             22536..23018
                     /locus_tag="J8S10_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HAZ9630361.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23135..23509
                     /locus_tag="J8S10_001778"
     CDS             23135..23509
                     /locus_tag="J8S10_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630362.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7734 a         4275 c         5075 g         6595 t
ORIGIN      
        1 taaaaaaact tggtacgcaa tcgctgtacc aagttttttt atttagcttt tgattaagcc
       61 ataaataata atttatataa gaatactgct acgacaccag cacagatagg tgctacaact
      121 ggtacccatg catatcccca ttgagaagaa cctttatgtt tcaatggaag aagtgcgtgt
      181 acaagacgtg gagcaaagtc gcgggctggg tttagtccag gacctgtagg accaccaagt
      241 gaagcaacta atgtccatac aaggaaacca agtgctaagt gagctgtacc aagattatct
      301 tggaagaatg gtgcttttgt aatacctagg gcaccaaaga ataaaacgaa tgaaccaaag
      361 aattcattga cgaaaccatt gaatttagaa ccaacgctgt tgattgttga gaatgtacct
      421 aacacatggt ttacgtcttc tgtttggtcg tagtaaggtt tgtaacaagc tactacgatc
      481 aattgtccaa tcgctgcacc aatcaattgt gcaatgatat aaggaacaac ttcagcccaa
      541 gggaatagac cattagatgc taaagcaatt gtaaatgctg ggttgatgtg gttaccgctg
      601 attccaccaa aaatcattgc tggcatcata accccgaatc catacccgac agcaatcagc
      661 atccagtcac tgccatatcc ttttgtacct tttaaatcta cgtttgctac agcaccgtta
      721 cctagaacga ttagtaatgc tgtaccaatc atttccgccg caagacgggt cattagtgag
      781 taatccataa atacctccaa aagttataaa aatgcaaaaa aaaaagaaac atcaacacga
      841 aaagcatcgg tgcagtgttt cgtgtcggaa ggatttctgc agtcttaaca aatgtgaata
      901 aaaaaatgaa ttccattact tataagaaac cagaccaaca gtaaaactcc aactcttttt
      961 aaaagttctc cacaaatcac caagcttaac tataaatata ccaaaaaaaa aacgtttttt
     1021 ttctcaaaaa ttgtatctta gaaacagcat gttttgaaac tttcagaaaa ggtttgttag
     1081 taaaatgaaa gctatacgta aggagtgttg tttgatgaaa ttttttcaag agtttttcat
     1141 tattattttc ttttctgtat taggagaagg catacggatt tttgctcatt tacctattcc
     1201 tggaagtatc ttaggtattc tttttttatt tttagcattt gaaatgcatc ttgttgatcc
     1261 tgaaaaaatc ggagcaactg gtgatttttt attgaataat ctagccattt tatttgttcc
     1321 tgctggtgta ggtttattgg aatattttga tgatattgct tcgatatggc ctgttttact
     1381 gggagcagtc gtcgtgtgtt ccatcgtcac gatggttgca gcgggaaaaa cggcagaagg
     1441 tgtagaagct ttgctgggct atgtccgtaa gaaaaaagca gaaagggtat ctgtaaacga
     1501 aatggaggag aatcaaattg actgagtttt ttgtgaatcc attatttggc ttaagtttga
     1561 ctttaggagt gtacgtatta tctgacaaat ttttgcggaa atataaactg cctgttttga
     1621 atcctctcgt attatcgatt gttgttatta tcttattttt gcatttttct gggatcagct
     1681 ataaagacta taatatcggg ggcaattttt tgactatgct gattactcct gcgacagtgg
     1741 cacttgccat ccctctttat aaaaacttcc gtttactgaa agagaatttt tatcctgtaa
     1801 tggctgcgat tttagcagga atagtcgcaa attgcttggt tagtgtaggg ttcggttact
     1861 tcttctctct tcataaagag atggtgatct cattactacc taaatctgta acgacggcta
     1921 tttctgtcga tttatctcat acgatgggcg gggtgaatgc cgtgacactt gctattgttg
     1981 tctctacagg tatttttggt tcgctgatcg ccactcatat tttccgccta ttcaagatcg
     2041 aaagtccagt tgctcgcggt gtggcgttag gaagtacttc tcatgctatt ggtacagcaa
     2101 aagcaatcga gattggtgaa atagaaggaa tcatttccgg acttgcgata tgcgtcaacg
     2161 gaatattgac cgttttattg ctaccgttat tctttcagcc ttttgctggc ttgttttgat
     2221 gcgaaaacca ctattttatg ctacaataac caaaacgttc gagcataaaa aaggagggaa
     2281 agacgtgtat ttgtcttccg agtatcttaa acaatttgat aaagatctat attataagat
     2341 tctcctccta gaaagttttg aggatcaagc ttggcatacc gctgcacaat tagcgcaagt
     2401 tgttcagctg gatgcccgca gcgtgtcgaa atacctgaac gagctgtcta aaaactatca
     2461 gcagtttagc ggtaagacac accctttgtt tacaaaaaat caccgttctg gttataactt
     2521 ttatgatacg ctcgattcaa ttgaacatga gcgttttttg atctatctcg tgcaaagtac
     2581 gctgaaattc cagttgctgc acgacatttt ttttgaagaa ttccatacaa tgtaccaatt
     2641 tgcgcaaaag cattacatta gtgaatctac tgctcatcga aaaatcaatg aatggaaaca
     2701 gcaactgcaa acttacggaa ttcggctgca acgaggtaca tatatcgctc aaggcgaaga
     2761 agaaatcatt cgactttact tgcatatgac attctggcag ttgtttcgag ggaaaatctg
     2821 gccatttgaa acgatttctc aaatggacgt aaagaatatg gcagaacata tcatggcttt
     2881 ttttaatgtt cgtctgaacg agatcaaaaa aagacgattg gaatatatgc taggtgcctt
     2941 ttttttaaga aaatcacaga agcattatgt tgtattgaat gagaaaaaaa gacggctgat
     3001 ttctgacaat ctgttgttcc agcgattttg ccaggtcatg gagccggtat ttcctaatta
     3061 ttttcaagta gaagacgagt taggcgcatt atttcttgta ctgatgactc gtgaagaata
     3121 ttatagtgat cctaagatac ggaagaaaat ttttgatttt catcaacaag caaaaacacc
     3181 gccctttaca gccctttcag aagcaaaagc cgctctttct ctttatcagg aagagcaggg
     3241 gctgccagca gaaaatctaa ccttcgaggc agaaaactat ttattcagca gtcatttttt
     3301 cgcctatctt tttcctaatg cgaaagaaac gattgatggc aatagtagtg attttattaa
     3361 tcatttagtt attgaaaaca aggaattgaa acaatggctc gtacattttt ttgaaagtag
     3421 acacaaacat cccaatcatc tggcatttaa aaatcatgcg tttttgatgg ggcggtatct
     3481 gactgtgttt aaaacattag gagcctttac tccacagctt ccaaagatca cgatcctttt
     3541 aatgacagat ttcccattat ttgaagagca actgttagag gagggattac ggacattttt
     3601 ccgtaatgag tatcagctga tttttctgcc aacagattat cgggggagag aagttgatct
     3661 tctgatttcg acaagtaaag tccaccgcaa accatgggcg gatcttgact attttattgt
     3721 gactgaagaa ctaaaattaa ttgattacat ccaactatct caaaaatttg aaatgattca
     3781 aaaacaaaaa ctattaaaac aataacaaag aaggagaaaa aagatgacat ttgaagaaat
     3841 tttaccagaa ttgaaaaaag gtgcaaagat tattcgtaaa ggatggagtg gatttgaact
     3901 ttatgttgtt ctcgtatccg atgatgaatt tgatggctgt ccggtgacgc cgtacttatt
     3961 gatcaaaaca agtgacgaag gtttttccag cttcgctcct acagtttgtg atattttagc
     4021 agatgattgg gcgatcgtag aatgaaaaac cagtatccag atctagctaa acaggttgta
     4081 tttatcacag gagctgcttc tggaattggt gctgcgcaag cccgagcgtt tcttgaacaa
     4141 gatgcttttg tatttggatt agatcaaaag ttcggtaaaa tggaagaaat ttctttgcga
     4201 tttcctgaaa cttttgccta cgcactaggt gatgttcgac aaatgaaaga actccaacaa
     4261 gcggtatcga aatgccaaaa tcattttggt gaagttacga ttttactgaa tacagcgggg
     4321 atattggatg cctacaaacc cttgatggaa actgacgaat cgctgtggga tctgatttat
     4381 gagacgaatg tgaaaagcat gtatcagctg acaaaaatca tccttcctga tatgatccgc
     4441 caaaaaagcg gaacgatcat caatatggct tcgattgctg gcttgattgc tggtggaggt
     4501 gggatcgctt atacaagcgc gaaacatgcg attgtcggat ttaccaaaca actcgctctg
     4561 gattacgcag gacagggtat ccgagtaaaa ggaattgctc caggagccat ccaaacacca
     4621 atgaatgcgg ctgattttga agggaaaggt gagatggcag agtgggtggc aaatgaaaca
     4681 ccagtcaagc gatgggcaca gccggaagaa gtagctgagc tgacgttatt tcttgcctct
     4741 cctcaagcaa gctacataca aggaacgatc atcccaatcg acggcggatg gttgttaaaa
     4801 taaccttgtg tttttttcaa gcttctgtat gataaaacta aagagagaaa caacggttga
     4861 tgataaaaaa agtcgatgac tgttcccgac attcgatgcc gaacagccag ttcaaaaaat
     4921 tctttttaat aatcgttaat attcgaaact aagcggcttt tcacgacctc ttgatataaa
     4981 cgatattcaa aagcttgcaa ctgcggtaac aagtccagcc aaatgaaaaa tataaggagc
     5041 tatttttatt tgaccattct tattacttgt tgcagggcag ctttttcact accttctgcg
     5101 acacttcagt tggaattttc ttcccatcct ttggtcgcgg tcattaccaa gataaaatta
     5161 tcttgcaaag gagaaataga acatggaaaa aaataatacc cgttcagcca aacgctggac
     5221 aacgacagat gtgactcgga tggcgctagt cactggttta tatgtggcag tgacgctggt
     5281 tttgtctgtc tttagctttg gagtgattca gattcgtctc tcggagatgt tcaactatct
     5341 gtccttgtat aacaaaagat acatcgtcgc ggtaacagcg ggagtagctt tggctaatat
     5401 tgcttctcct cttggactga tagatgttgc agtaggaagc gtcagcacgc tgcttgtatt
     5461 gcttatcaac tataaaatca ctagtcgcat caaaaacatg aaaatcaaaa tggccgtgac
     5521 agcatgcgta tttgcttttt ccatgtttac agtagctggt cagctaacga ttttatatca
     5581 actacctttt ttcttgaatt ggtgggtgat tgctttagga gaattggcat caatgattgt
     5641 cggtgggata attatttatt ggatcggtaa aaaagtggat ttgtcaaaat aaagatctgt
     5701 ttaatttaaa atagggcagc atggaagaga ctgaatgttg agtcttcttc catgctgctt
     5761 ttttgattaa tttgtatgaa gaaatcgatt tagccgtttt ttcatcaaga taccgatata
     5821 agctgctcca gttgccttga ttgcttccgg cagtaaaaac ggcagtagtc cactggcaaa
     5881 tgcagttgta aaagtaagat caccacttat tttcagccag atcgttccgc agatcaatgc
     5941 agcaagagag cccattagat tggcaaagat tgcatataag taatgagcat ccgttctttc
     6001 gatcatccaa ccagttatcc acgtttgtaa gagaaatcca atcaaatatc cgccagttgg
     6061 cccaaataaa acagctatac ctccagtcat ccctgaaaat acaggaagac caatcaagcc
     6121 aagtaaaaga taaactccaa cagatatcaa tcctagtttt cttccgagaa aagttgctgt
     6181 taatccaata gcaaatgttt gccctgtcaa aggaaccaaa ccaaaaggaa tggtcatctg
     6241 agaaaggaca gaaataatcg cggcaaattc cgcagcaagt atcaattctt tcaatgttcg
     6301 gttcataacg ccctcttttc gttaacttaa tatttttatt tggttaacga aattgtaaaa
     6361 caaagtgatt actttgtaaa tagaaaatat aaaaaaagac cagctatcca atagatagcg
     6421 gtctttttca agaaagcttt tgaaattata agctttggtt gtagtattca acgacaagag
     6481 cttcgtcgat ttctggatat agttcgtcac gttctggtaa acgagtcaat gaaccttcca
     6541 atttttcagc gtcaaagctt acgaatgctg ggcgtccaac agttgcttct acagcttctt
     6601 ttactgttac gatgttttgt gatttttcac gaactgagat cacttgaccc acttctacgt
     6661 ggtatgaagg gatatcaacg cgtttgccat caactaaaat gtgaccatgg ttaactaatt
     6721 gacgtgcttg acgacgagtc gttgcaagtc ctaaacggta aacaacattg tctaaacgtt
     6781 gttctagtaa gatcatgaag ttaacaccat gtttaccttc tttgattttg ctagctttta
     6841 cgaacaagtt acggaattga cgttcgttca ttccgtacat gtgacgaagt ttttgttttt
     6901 cagttaattg catgccgtat tctgattgtt tgccacggct attaggtcca tgttgacctg
     6961 gtgcgtaagg gcgacgtgct aattcttttc ctgtgcctga caatgagatg cctaagcgac
     7021 gagaaatttt ccatgatggt cctgtataac gagacattaa aatttcctcc aatgaatata
     7081 agtttttgga gtaaaataat ccgttgaaaa attcataatc atatagtttg ttcttcaatc
     7141 ttcacctttg cagccgcggt tacacaatcg aacccgagac ggggcaacaa actagggatg
     7201 agttattatt tttctgctgc attattttac acaaattaca gtatatgata gatcatccac
     7261 gaatgtcaag ataattagta cataaaaacg ctttacaaac ctaggctgtc tttataaaat
     7321 gagagggtat gtgcaaatgg aaaaaagcga aggaagttta aggagaaaat caatgaatcc
     7381 ggtatcacca ttatttgaga aaatcgatgc ttcaattgaa aagaaggcga atctttttga
     7441 aaacagcttt tcacgttacg ctgttcgagc ggttctcgcc tgtttgtttt tgactttagg
     7501 aacggctgtg gcatttgcga tcgcgatgaa gggggaagat atcgcgcatg gtctaggaaa
     7561 gattttatac gcatttatgt tcagctgggg tctggtcatg attctataca tgaacgccga
     7621 attaggaaca tcgaatatgc tttatatgac cgtgggtgtt tttcggcaga gacttgcttt
     7681 aagtaaggca gccaagattc tatttgcctg tatttttttc aatatgattg gcggtatatt
     7741 atgtggattt ctaatttcta tgactacgcc atttcaagat ttaacgttgg acaactttat
     7801 gttagaatca atagcagtaa aactagcaaa accttcagca acgattttgg tggaagggat
     7861 gtttgcgaat atcgttgtca ataccgctgt actgatcagc atgcggatga aagaggatgt
     7921 cggaaaagtg atcacagtcg tattcatcat tttcattttt gcttttttag gatatgaaca
     7981 cgtgatagcg aattttcctg cctttacgct tacttacttt gcttctcacg gacagatgga
     8041 tggaatgaca gtcagcaatg tgttacataa tttgtttttt gctttggcag gaaattatat
     8101 tggtggcggt ttagtaatgg gactgggata tgcttggctg aatcagtcaa aatcatccta
     8161 tgtggactaa aaagtcgttc attaaagggg aagtgccatg gaagttttag tttttccaaa
     8221 aaatgaggaa aaagcgttac aaatggaaaa gtacatgaaa aatctttttt cctttgctgg
     8281 agtacctaag ccggaacgcg ctcttttaca acaaccgtta ctggatgaga gcaaaaattt
     8341 atctatttct gaagttttag cttttgttca ttattattat gaacaaatcg aaagagagta
     8401 tcagtatgta gcgatcgatt tagtccagaa aaacatcaaa cggcttacat ttgaagactt
     8461 agtcgtattg ttgccactag ttcagaaaaa agaatggtgg gacagcatcg actcttggag
     8521 aaaagtatac agcacatggt gtaaagccta cccagagcag cgtgaagaag tctttcaatt
     8581 gtttgaaaaa aaggaagatt tttggctacg tcgaatagca atcacgttgc aattaggtta
     8641 taaacagcaa acagacacag gactattgat ccgagcaata gacgaagatc gtcaaacaaa
     8701 ggaattcttt atccaaaaag caattggttg ggcattacgc gattatagta agaccgatgc
     8761 cgattgggta aaaagacagc tgacaacaga tttgagtaag ttagctgttc gagaggcaag
     8821 taagtattta taagaaagcg agacgacaag agatgagacg caaattattt gcttttgata
     8881 ttgatggaac gttgttagat tcaaacaaac aagctttaga tagcacaaga gaagcattgg
     8941 aaaaattacg caaagccggt catctggtca cgattgctac agggcggagc cgatttcatg
     9001 cgcaagagat cattcgcgat cttgatttta cgaactacat tttatgtaat ggagcggccg
     9061 gttttttaga ccatgaacaa gtatataaga atttactaga tcgcgaccag ttggatgcgt
     9121 tcgttcaaga agcgcatcat gagcagatcg atacagcttt tgtcagctta gacaatatca
     9181 agcgttcttc ttccaatgat gtaacggtga tggaagaagc gatgcattct ttcggtgctg
     9241 tcttgcctga attagatcag ttttttgcag aggaacaaga aatataccaa gcgttagcat
     9301 ttttcgatca aacatatgat gggaagttct cttcatatga taaaattcga tttgtccgct
     9361 ggcatgagaa cagtgtagat gtcgtaccta aaaatggttc taaagcagcg acaattctgc
     9421 acttagcaga acaagtaggc atccctcatg aagacatcat cagctttggc gatggacaaa
     9481 acgaccgtga aatgttgcgc atgtcaggaa ttgggatagc tatggggaat gctgtgccag
     9541 aagtacaagc agaagctaag atggtcactg atacaaacga tcaggatgga atttggaagg
     9601 cattgaaaga gttaagcgtg atttaaaaga ggttgtgaaa aagctgttct gcatcaagta
     9661 ataagcccag ccaaacaaaa atagctcctc ctatttttcg tttttctggg cttattaccg
     9721 cagatgcaag ctttcgaaca ccgtttaagg aagaggtcgt gacagaagtg gtcagtttca
     9781 agaaataaga agggatttac gaaaattgct tctcaaattt ttgtaaaatt acggcttatt
     9841 tctgaagaag tagatgaaac aacgtttatt cgggaaatgg gactgtgaca agatgtttgt
     9901 catagtccca tttttttatt ttatttttca aaactaagaa ataccaggaa agagttcctt
     9961 ttgtttgacc ttttctttct tattgaaaac aactataata tagagtgatg ttaaaagaga
    10021 agaggaattt agtgtgcggg tattgtttat tggtgatgta gtaggttcaa tgggacgaga
    10081 gatgattact gaatatcttc ctagattgaa gaagaagtac cgtccgcaag taacgattgt
    10141 aaatggtgag aatgccgctt ctggacgtgg aatcacagaa aaaatctata aaaaattttt
    10201 gcaagacggc gtagatgtcg tgacgatggg gaatcatacg tgggacaacc gcggaatctt
    10261 tgagtttgta aatgaagcta aaaagatggt tcgtccggca aattttccgg aagggacgcc
    10321 tggacaaggg atggtctttg tcaaagtgaa ccaagtcgaa ctggcagtga tcaacatgca
    10381 ggctcgttct tttatggtgg acttggatga tccttttcgt aaaatgaatg agctggtaga
    10441 agaagccaga aaacgtacgc cgatcatttt tgtagatttt catggagaaa caacaagtga
    10501 aaaacaagca atgggctggt ttttagatgg gaaagtttca gcagtggtcg gtacacatac
    10561 acacgttcag acaaatgatg cgcgaatttt gccaagagga acagcgtatc tgacagacgt
    10621 tgggatgaca ggtccctatg atggtatttt gggtatgcgc agagaacctg taatcgaaaa
    10681 gtttctgact gcattaccaa aacgttttga agttgtggaa caaggccgat cgattttaag
    10741 cggctgtatc ttggaattgg atgatacgac aggtcatgca aaagaaatcc agctgattca
    10801 gatcaacgat gatcgaccgt tcatggagta gaaagagagg cagttttttg cagcaggagc
    10861 cggaaattca aaaagaagta aggaaactga caaaactttt aagagagaat gaaacgatca
    10921 ttcgctacaa agaacttgaa gaaaagatcc agcaaaacca gtatttagct gagttgagag
    10981 aaaaaatcaa acaagcgcaa aaagatgctg ttcattttgc ccactatgac aaaccagcag
    11041 cagaaaaaga agcaatcaaa caagcggatc aattcatgca agaatttgat cagcatccgc
    11101 ttgttgtagc ttatagaaaa cagctgttgg aagcagatga tctgcttcat catttaacaa
    11161 ctatgataca agaagaaatc aatggacaaa tagaggagga aaaacatgcc tcaaaaaact
    11221 aaaaatactc ctatgatgga acaatatcta agcatcaagg cccaatacca agatgctttt
    11281 ttgttctatc gtttaggaga cttttatgaa ctattttacg aagatgcgat caaagcgtca
    11341 cagcttttgg aattaacgtt gacgagcaga aatcgaaatg cagaagaacc tattcctatg
    11401 tgcggtgtac ctcaccatgc agcacaagga tatatcgatg ccttgattga aaaaggctat
    11461 aaagtagcga tttgcgagca ggtagaagat ccaaagacga ctaaagggat ggtcaagcgc
    11521 gaagtgatcc agctagtcac tcctggtaca gtcatggaca gcaaaggatt gtcggcaaaa
    11581 gacaacaatt ttttaacagc tgtagttagt caaggaaatg aatttggctt tgcttatgcc
    11641 gatttaagta cgggagaatt gaagacggct cggttgcatg atgaagaagc tgttttaaat
    11701 gaagcctctg cattgcagac aaaagaactc gtattaggca gtgagatcac tgataccctt
    11761 cgtgaacagc taagcgggcg tttagggcta gtcttttctc aacaaaatga gatggaagaa
    11821 aacgcggaat ttagcttttt gacaagcgaa ctagtcgatc cgctggaaaa agaagcaacc
    11881 ggcaaactat tgacttattt atcggtgaca caaaagcgga gtttagctca tatccaaaaa
    11941 gcagtagaat accaaccaga tcattttttg aaaatggatt attattcaaa attcaaccta
    12001 gaattaagcc aatctattcg gactgggaaa aagcacggca ctcttctatg gttgttagat
    12061 gaaacaaaaa cagcaatggg tggccgttta ctaaaacaat ggctagaccg tccgcttatc
    12121 caggcaaaac aaattaaagc aagacaagaa atggtcgctt ctttgctaga cagctatttt
    12181 gaacgtatcg atttgcagtc agcattaacg aaagtctatg atctggaacg cctagcaggt
    12241 cgagtagctt tcggtaatgt caatgggcga gacttgatcc agctgaaaac ttctttagaa
    12301 caagtgccaa tgatcagagg gttgattgaa ggaatcgatc aaggtcaatg gcaaagtctg
    12361 ctttcagaaa tgcagccgat ggaccatctc gtccaattga tcgaccaagc tatccaagat
    12421 gatccgccgt tacaaataac ggaaggaaac atcatcaaag atggattcaa tgagcagctc
    12481 gatatgtacc gttctgctat gagaaacgga aagaaatggt tggcagaact tgaagcaaaa
    12541 gagcgtcaag aaacaggaat caagaactta aaaatcggat ttaaccgcgt tttcggttat
    12601 tatatagaaa ttacaaaagc aaatcttgga aatgcagaac tggagaagta tgaacgaaaa
    12661 caaactttag caaatgcaga gcgtttcatc acaccagaac taaaagaatt ggagacacaa
    12721 atcctcgaag cagaagaaaa atctgttgat ttagaatatc agttgttttt agctgtgaga
    12781 gaagaagtca aaaaggctat ccagccgcta caagtacttg caaaagcaat cagtgcagta
    12841 gatgtgctac aaagttttgc aacgatcagc gaacgctatc agtatgttcg gccagaactt
    12901 gtcagtgaca agcatcagct tctgatcaaa gacggacgac atcctgtagt agaaaaagta
    12961 ttaggacatc aggaatatat ccctaacagc gtagaaatgg cagaagacga aatgatcttg
    13021 ctgattacag gaccgaatat gtctggtaaa agtacgtata tgcgacagtt ggcattaact
    13081 gttctgatgg cgcaaatggg ctgtttcgtt ccggcaaaac aagcagtttt acctattttt
    13141 gatcggattt ttacccgaat tggtgcaagt gacgacttaa ttgctggaca aagtactttt
    13201 atggtagaga tgatggaagc caatcaagcc ctgcgttatg ctacgccaaa cagtttgatt
    13261 ttgtttgacg aactagggcg aggaacagca acctatgacg gaatggcgtt ggcccaagca
    13321 atcatcgaat atatccatcg tcatgtacaa gcaaaaacac tcttttctac tcattatcat
    13381 gaactgacgg tacttgagaa agaacttccg cagcttaaaa atgtccatgt tggagccgtt
    13441 gaaaaagacg gagaagttgt cttcttgcat aaaatgatgg atggacctgc ggataaaagc
    13501 tacggcatac atgtggcaaa gatcgcagga ttgccttcca atctactaga acgagcagca
    13561 gatatcctgc atacgctaga aaatggcgat aacggacacc atactgttcc agctgaagta
    13621 gaagagaaaa ctaaaacagc caaacaggag caaataaaac cacctgcaga aaaagtaaat
    13681 caagaccata tacaagaccg tgtaaaagaa gaaaaccaac agctttcttt attcagtgaa
    13741 ttatccgaaa atgaaacaga agtcattgaa tcactgaagc aaataaattt actagaaatg
    13801 acgccaatgg atgcactaaa cacattatat gaattacaaa aacaactgta ggaagaaggc
    13861 ggatatcgat ggccaaaatc caagaattat ctgaacgttt agctaatcag atcgctgcgg
    13921 gagaagtagt ggagcgacca gcttccgttg tgaaagaatt agtggaaaat gcaattgacg
    13981 ccggcagtac tcagattgat atcttagttg aagaagcggg actgcggacg atccaagtga
    14041 ttgataacgg agaaggcatt ttggcagacg acgtagagaa tgccttcaag cggcatgcga
    14101 caagtaagat ccataatcgc gacgatcttt ttcgcatacg aacgctgggc tttcgagggg
    14161 aagctttgcc aagtattgcc tctgtttctg aaatgactct ggaaacggcg aatcaggaag
    14221 aaaaacaagg cacctatctg tcgctgaaag gcggagaagt tattgagcat cgaccagcac
    14281 cactgcgtca aggaacgaag attaccgtca gcaatctgtt tttcaatacg ccagcccgct
    14341 tgaaatacgt gaaaacactg cacacagaat tagcgaacat cggggacatc gtcaatcgac
    14401 tggcattgag tcatccatcg attgcttttc gtttagtaca tgatggaaac aaaatgctgg
    14461 caactgctgg aaatggcgat ctgaaacaaa caattgcggg aatctacgga ttatctaccg
    14521 caaaaaaaat gctgaaaatc gaaggaaaag atctagattt tgagttattt ggctatgttt
    14581 cattgcctga ggtgactcgt gccagtagga attacttatc gacgatcatc aatggacgtt
    14641 ttatcaagaa cttttccttg aataaagcaa tcgttgcagg ttatgggtca aaattaatgg
    14701 tcggtcgttt ccctattgct gtattggaaa tcaaaatgga cccgctttta gtagatgtaa
    14761 atgttcatcc gacgaagcag gaagtccggc tgtcgaagga aaaagaacta acagagctaa
    14821 ttagtaacgc cattcaaaaa gcattgtctc aagaaaatct gattccaagt gcagcggata
    14881 atctacggtt taagaaaaaa gtacctgatc agcctaaaac agaacaaatc gaaatcgatt
    14941 tgtcctacgc ttttgaagaa gaaaaaccta aaaagccaag tagtttgaat tttgatcgac
    15001 agacaggtac ctttttcgta gaagaactaa agaacacatt tgttgacaga attgttgata
    15061 agtctgtgga aaatgttgaa aactattctg gtttttctga agaaaacacc acttatccag
    15121 aaaaaacagc gaaaacggtg gataagtttg gtgaaaatgt tgataacttt gtagaaaaaa
    15181 cagtggaaaa atctgaaaag aaagaatttc ccattgtgga taacatggag aaaacaaatg
    15241 aagaacaagc agataaatcc gtagaagagg atgaaaagat ttacgaggaa gaattgacac
    15301 tccatcctga atttgatttc actcaaggaa acgacaaaac attagaacaa gccatcaaga
    15361 aattagaaac ggaaaaacca gtacaacgtt ttcctcagtt ggaatatttt ggacagatgc
    15421 acggaacgta tctttttgcc caaagtagcg atgggttgta catcattgat cagcatgctg
    15481 cccaagagcg cattaagtat gaatatttcc gggaaaaaat tggggaagta tctgatgatc
    15541 tgcaagaatt gcttgttcca tttgtgttag actatccaaa cagtgatgct ttgaaattaa
    15601 aagagcaaaa acacttgcta gaagatgcag ggatttattt agaagaattt ggtcaaaaca
    15661 gctttattgt acgggcccat cctacttggt atcccaatgg agaagaagaa tcgattattc
    15721 gggagatgat cgatatgctg ctgacaactg gaagtgtgag tgtaaaaaaa ttccgtgaag
    15781 caacagcaat catgatgagt tgcaaacgat cgattaaagc caaccattat ttgaatgaag
    15841 cacaagcacg tgtgctgctg aaggatctgg cacgatgcga aaatcctttc aattgtcccc
    15901 atggccgtcc agtattgatt cactttacca attcggatat ggaaaggatg ttcaaacgaa
    15961 tccaagaccc gcattaagtc aaagagaaga gggaaaacat gaagattgta ttagcatccc
    16021 aatcaccaag aagaaaagag ttattggctc atatcgtttc agaattcgag attgaacctg
    16081 ctgatatcga tgaaacgcca tttccagacg aacagcccgt cgattatgtt cgtagaatgg
    16141 ctgaagaaaa agcacgaact gtctgggaac aagatgaaaa agaagaccat ttagtgattg
    16201 ccagtgacac gactgttgtt ctcaatcaag agatcatggg taaaccagaa gatctggctg
    16261 aggctgaatt catgctgaaa aaactaagcg gggaaacaca tactgtatat acagctgttg
    16321 ttttaaaaac aaaggaacga gaagaacgga tactagcaga agcacatgtc actttttatc
    16381 ctttgacaga cgaagagatc aaacgctact tggagacggg ggattatgcg gataaggcag
    16441 gggcatacgg catccaaaat gctgcgagtg tattcgtcaa agaaatttct ggagattatt
    16501 acagtatcgt aggatttccg attggtgctg tcaatcaggc actgaaaaca ttcatttaaa
    16561 caaaaaagcg gactatctga ttttcgattg aaaatccatg atagcccgtt ttttttattg
    16621 aaaagattac ttatctactc tgactaagat tttacttcag ctttaccgac tgcttcgccc
    16681 gggcgaacaa gtcctgattg gtcaagagaa agtcctgcaa ctttttcatt attggtcaaa
    16741 gcaacaataa tgtcagtttt cttgccagct tgttctattt ctggcaaatc catttcagca
    16801 atcagggtct ctggtgtgac aaggtatcct tctttcacga atacattgaa aggaacaccc
    16861 tttagttcaa cagtatctaa tcccatgtga acaagtactt ccagcccctc attagaaaga
    16921 ataccaatgg catgttttgt ttcaaagaca ctcgtcactt taccgtttac tggtgcatag
    16981 actttgccgt ttgacggttc gacagcataa ccgtcaccca tcattttttg tgagaaaact
    17041 gggtcattta cttcagttat ttccttgatg gtccctgcag cgactgcgaa taatgtttct
    17101 tttgttgcaa ctgccgtacc agttgctgaa acaggttcga aagactgtgg cgttgctgtt
    17161 gcgccatttg ctgtttgaag ttgtacatca gcagcatttt caggaacagc aggatcaatc
    17221 ttattcaaaa ttccctgacg tctaaagatg atcgtcaagc caaatggaat gatgacagca
    17281 atgatcattg cgatgatgaa aggtacccat gtttctgctt ggatagctag tattcctggc
    17341 aaaccgccta ctccgatcgc gttagctcga acacccatca agttagcaaa catgccagct
    17401 aatccagagc cgaccattgc agcgacgaaa ggatagacgt atttcaaatt gattccgaac
    17461 atagcaggtt cagttacgcc taagtaacaa gaaatcattg ctggaatcga gatttgttct
    17521 tcttttttat tcccacgatg taagaagatg atggctaaga ctgcagagcc ttgggcgata
    17581 tttgataaag caatcatcgg ccataaattc gttgatccga aatctgcaat cagctgcata
    17641 tcgatggcat tggtcatatg gtggagacca gtaatcacta aaggagcata caggaatccg
    17701 aatacggcac taaacaacca gctgatagaa gacgtcaatc cagtatttac gatatttgag
    17761 atccagcttc cgactgtcca gccgatagga cctaaaataa cgtgtgcagc taaaacagtt
    17821 ggtaacaatg aaaacaatgg aacaaaaatc atcgagatcg actgagggat atatttgcgg
    17881 aagaagattt ctagatacgc taacataaac cctgccagca tggctggaat aacttgcgct
    17941 tgataaccaa tcatctggac ttgagcaaaa ccaaaatccc aaaatggaat atctgctgcg
    18001 gctgtggaag ctacactata agcatttaat aattgcggag aaactaacgt aattcctaaa
    18061 acgattccta atatttgtgt agtacccatc ttttttgcaa tactccaagt gatacctact
    18121 ggaagaaaat ggaaaattgc ttcaccgggt aaccacaaaa aggcattgac accattccaa
    18181 aacttcgagt gttcaacgat tgttccacca agactttcaa actggatacc ttcaagtaca
    18241 tttctgaatc caaggatcaa tccaccgaca atgattgcag gaatcagtgg tgtaaagatt
    18301 tctgctaaaa cggcaatagc acgttgaacg ggatgaaggt tttgttttgc agctgctttt
    18361 ccttgttctt tggaaacccc ttcaactcca gatactgcaa cgaagtcgtt ataaaaagta
    18421 gaaacatcgt ttcctatgat gacttggaac tgtcctgcat tcgtgaacat cccttttacg
    18481 ctaggtatat cttcgatcgc tttttcgtcc gcttttcctg gatcattcag gacaaaacgc
    18541 atacgagtcg cacaatgact aactgcagca atattttctt ttccgccgat atcatgtaac
    18601 agcttctcgg catctgcttg atattttgcc atatcaataa acccctttct cttaacttgt
    18661 ctatgcaagt tgtttcttca tttactatac tttttttcgg agagaattgc aagcgtttta
    18721 ttaaaaagta cgagagaaaa tgatatcgtt ttaaaaagct taaaataagc ttttcttaaa
    18781 aataggaaca ttgaaataca aaaagagctg tagtatagtg aagaaatgat ggaagaacga
    18841 gtgagggaaa aaacatgaat aagttcaatg aaattttttt agatttggaa cagaaaattt
    18901 tagcgaaaga atatcctccg cattcgcttt tacccagtga gaaccaattg atcaaaattt
    18961 atggtgtttc acgagaaaca attagaaaag cgctgaatct tttgactacg gaaggttata
    19021 ttcaaaaaaa acaaggaaaa ggttcgatcg tactggatcg gaatcgcttc gactttccta
    19081 tttctggatt gactagctat aaagagctac aggagaccca acgtattcca agtgaaacga
    19141 tcatccatac gttagaagaa acagaagtga caaaagcatt gaacgagatc actggctggg
    19201 agatcggtgc gcctgtttgg catttgatac gcgaaagaaa aatcaatggc gaagtagtta
    19261 tattagacac cgattatcta ttaaaggaaa tcgttcctat tttaactcca gcacaagcac
    19321 aaggatcgat ctatgaatat tttgaaaatg agctttcttt gacgattgct tacgcgcaaa
    19381 aggagatcac agtagaagaa gtaacggaaa tcatgaaaac agcgatggat cttcacgatg
    19441 acacttatgc agtagtagtc agaagcctcg ttcatctgga agatacccgc tgtttcgagt
    19501 attctgagtc ggttcaccga ttagataaat tccgtttcgt tgagtttgcc cgacgccgaa
    19561 aagtgtaaat agttcaaaag aaagcaaatt gttggcatct gtccactttg gcgctatgat
    19621 aggatcacaa agggggcatt tttaatggat aaaccaataa gaccagaaaa agaagaactg
    19681 aaagaaaagt tatcacccat ggcttatgca gtcacacaag aaaatgcaac agaacgacca
    19741 tttagcggga aatatgatga tttttacgaa aaggggatct atgtagatat cgtcagcggt
    19801 gaaccgttat tcagctctgc agaaaaatat gatgcaggtt gtggctggcc atcattcagc
    19861 aaaccaataa cgaaaagaca agtgcgcgaa aaagccgatt tttctcatgg catgcatcga
    19921 atagaagttc gaagcaaaga agcagattct catctcggac atgtgtttac cgatggacca
    19981 gtagatcaag gtggtctacg ttactgcatc aattctgcct cactgaaatt cattccatat
    20041 gaaaagatgg atgaattagg ttatggggaa ttcaaatcac ttgtagaata atggaaatac
    20101 acaaagagcg gtacaatacg gggatttact cgatcgtccg ctcttttttt attcaagcga
    20161 ttgctatttg aaagaaacgc tccctagact ccttttttca caaggtgaaa tgtgctacaa
    20221 taaagggaac gtatgtgtgc aaaagaaaga ggactagaat atgtatgaat atctgacagg
    20281 tgtggttacc tttatcaacc cctattacat agtagtagaa accaatggta tcggctacca
    20341 gatcgcacta ggaaatcctt accgctacag tagcaaacta aatcaaaaaa taaaaattta
    20401 tgtccatcag gtaatacgtg aagatgcgca tcttctgtat ggatttgatt cgctagaaga
    20461 aaagcaactg tttttgcgat tagtaagtgt ttcaggaatc ggtccgaaaa gtgcccttgc
    20521 aatcatggca agcgaagacc actccggttt gattcaagca gtagaatcca gtgatgtcac
    20581 ttatttgacg aaatttccag gagtagggaa aaagacagca caacaaatga tcttggatct
    20641 aaaaggaaaa ttcggtgagc tgagtatcga tacacctttt agtctatttg atgaagcaaa
    20701 cacaaaagac gctacagctc tatctgaagc aatggaagct ctctcggctc ttggttacag
    20761 tgatcgagaa atcaaacgtg tagaaaaaca attaaaagaa gtagataatc agacaacgga
    20821 tgagtatcta cgccaagcac tcaagctaat gatgaaaaaa taaggaggag accaaatgac
    20881 agatgaatac ttgttatcac cagaatctgg cgaaaatgaa ctgagtttgg aaaaatctct
    20941 tcgaccacag ctgctttctc aatatatcgg acagagaaaa gtcaaacaag aacttcagat
    21001 ttacatcgaa gctgccagaa atcgggaaga acctttagat catgttctgt tgtacgggcc
    21061 tcctggatta ggaaaaacga cgatggccat ggtcattgct aatgagatga ccgtaaatat
    21121 tcgtacgacg agtggccctg ctatcgaacg tccgggtgac ttagtagcaa tcttgaatga
    21181 actggaagca ggggatgtcc tgtttatcga tgagatccat cgattaccta gagtggtaga
    21241 agagatgctt tattcagcta tggaagattt ctatgtagat atcatggtag gacaagggcc
    21301 aaccgcacat ccggttcatt tccctcttcc tccctttact ttgattggcg cgacgacacg
    21361 ggcaggtatg ctttctgcac ctttacgaga tcgatttggc atcatttctc atatggaata
    21421 ttatgacgaa caggatctgc aggagatcgt tttacgttct tcggatattt ttcaaacaga
    21481 gatcattgaa gaaggggcat tggaaattgc tcgccgatca cgaggaacgc ctagaatcgc
    21541 taatcgcttg ctcaaacggg ttcgtgattt tgcgcaagtc caaggagacg ggaaaatcga
    21601 tcgtcctata gcggatcagg cacttacttt gctacaggtc gatcaggctg gattggatta
    21661 tgttgaccag aaattgttgc gaacaatgat cgagttatat ggcggcggac cagtagggtt
    21721 aagtacgctt tcagtaaaca taggagaaga gcgtgagacg gtagaagata tgtatgaacc
    21781 gtatctgatc caaaaaggat ttttaaagcg tacacctaga gggcgaattg ctactgctta
    21841 tgcctatgaa cattttggtt acgactatca tatatgattt ttgcttttag attggaggaa
    21901 aatgaatgag tgatacaaca cgtacgaaac aattgatcaa aaacgtattg attgatttgt
    21961 gccaaacgca atcttttcga aaaatcagcg tccaaaaaat cgcaaacgaa gcaaaaatca
    22021 atcgacaaac attttattat cattttacag ataaatacga tttgcttcgt tgggtctatt
    22081 gtgaggatgc attgcattat ttagatccac aatgtctttc acttgataat tgggaagagc
    22141 aagcattgaa aatgctgaaa gcaattgctg agaagaaaga attttatgca aatactgtgc
    22201 tttctgaccc agaaatttta caaaaagagt tttctcaact gatccaaaaa tcatttatca
    22261 agatttttga acaaatggat gaagaaagac aactttctgc aagagacaaa ctattttatg
    22321 ctcgtttttt ttcttacggt tgcagtggtg tattagtcaa ttggatcacg aatgaatatg
    22381 aagaaacacc gatggaaatc gctatgcagc ttttccgttt agccaaggat acggaattat
    22441 attcttatcg tctttatgca aaagaagagt tggaagaaca gtaatagaaa aattttttgt
    22501 tggaaaagca ataatcgcta aaaggagatg gggaaatgac aaaaatttta tttgtttgtt
    22561 tgggaaatat ttgccgttca ccgatggcag aaggcttgct gagaaaacga atagcattag
    22621 aaggaaggga agcagaattt tttgtggatt ctgctgctac aagcacgtat gaagttggaa
    22681 agacaccgca ccctggaacg aaaaaaatat taaaccaaga aaaagtagat atgacgaata
    22741 tggttgctcg gcaaatcaca ccccacgatt ttgaaacttt tgattggatc attggcatgg
    22801 atcaagaaaa tgtagaagaa ctgaaacgaa gagcaccacg ctcagcgcag gggaaaatcc
    22861 atttgttttt aagtagcatt cctggaaaag aaaaagaaaa tgttcccgac ccatactata
    22921 ccaataactt tgatgagaca tatcacttga tcacagaagg cctgaatcat tggtggaata
    22981 tttggattga tgaaaataaa ataacaaaca atttgtaaag ttaacgcttt ctttttaagg
    23041 cgatgttaga gcatttcctt gtttttttgt aaaatgttag gtaaaataaa attaattaag
    23101 taacactttc ttagctaaag gaggagtgca ttcgatgaac gaagagacag tatcgccaat
    23161 gaagaagctt acgaagttag ttactcatac ttcgtatcaa ctttttgatt cttttgtaaa
    23221 tgacactgaa gaacatgcta agaatgtacg attgcaagga aagtttattc ttgagctgca
    23281 aaaagctgct actgaacata gtctagttat cttacaagta agagcaaatc gtttgagtag
    23341 caagtatgaa acgatctcag gctgggtggc gacaaaaacg gtcgaaaaag accgagtgat
    23401 gatccgccta caaaacgaag agcagcagat ccggatggtt cctgtagaac aaattgaaaa
    23461 aataacaatc ctttcaccag caggggaaca ggaacggtta tcaaaataat ttataccaga
    23521 tagaaaagca cgtatgagct tgtaccatca atcattacta atcaaaaata accgaatgct
    23581 ttaagctgat atcagtaaaa cggaacgttt taggatgagt atcatagcat gacagcattc
    23641 ggttgattag ttgaatcgat tggatggtac aagtttttt
//
LOCUS       DADQDV010000043        23373 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.043, whole genome shotgun sequence.
ACCESSION   DADQDV010000043 DADQDV010000000
VERSION     DADQDV010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 23373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23373
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.043"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..143
                     /locus_tag="J8S10_001779"
     CDS             <1..143
                     /locus_tag="J8S10_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630363.1"
                     /translation="EYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQETIKKLRI
                     GG"
     gene            146..976
                     /locus_tag="J8S10_001780"
     CDS             146..976
                     /locus_tag="J8S10_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HAZ9630364.1"
                     /translation="MAEISWIKLKTTMFDDEKIRLIQAVPESDAIIVIWIRLLVLAGK
                     TNDDGLIYIQRNMPYTEEMLATLFGKNVNTVRLALTTLANFNMIDLSSDGLIAISNWE
                     KHQNIEGMDKVRLKNAERNRKYRERKRQERLKLENDVSVTSRDGTDKDIEEDKDIDKE
                     EKKGKYSDEHLRLAKKLQSNLTEDFPKEMNKVDIEKWADTIRLMEERDKASIEAIEYV
                     INWLPTNEFWFGNIRSAKKLREKFEKLKFEIKADKKNHKKQSQKLQYSNPSEYDDLPI
                     "
     gene            993..1844
                     /locus_tag="J8S10_001781"
     CDS             993..1844
                     /locus_tag="J8S10_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAZ9630365.1"
                     /translation="MESLANAMEKLIRRVLVQSGKCPECSEPLYSWRAKNKDGSERCK
                     PTCMSCGYKALRVKEDIQTERIYNDSLKARALSFFQNGSVLTDKTLFKCKMENYHVVD
                     QETKIALEKAKSYTNEVLLNHPAHFILSGKSGSGKSHLSMATAWEILERSNYDKKILF
                     ISYQELLEQIKFSYNNTELRKEIEGSLIADIKTTDLVVFDDIGAELGSGVSNSRQFTN
                     NTLNTLLEARQNKATIITTNLSGPELREAYGERIVSRIFKNSEGYALKFQQTADKRIK
                     PVKGSIA"
     gene            1841..2200
                     /locus_tag="J8S10_001782"
     CDS             1841..2200
                     /locus_tag="J8S10_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HAZ9630366.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAEANGWKVKLQER
                     FELMPKFELDGKKYRKIEYIPDFTFYKNGKLVKVVDVKGMQTKDFKIKAKLFCHQYQA
                     PLILAKKYRNTFKEERF"
     gene            2215..2376
                     /locus_tag="J8S10_001783"
     CDS             2215..2376
                     /locus_tag="J8S10_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HAZ9630367.1"
                     /translation="MTTEEVIQMRIRSIQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIRRLEE"
     gene            2379..2678
                     /locus_tag="J8S10_001784"
     CDS             2379..2678
                     /locus_tag="J8S10_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630368.1"
                     /translation="MDKKATMKRIVELTKSESWQEDKEIVAEVQRIGKSMWTEKPKRR
                     TPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
     gene            2678..2995
                     /locus_tag="J8S10_001785"
     CDS             2678..2995
                     /locus_tag="J8S10_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HAZ9630369.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKSKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYKEILDEYME
                     GSK"
     gene            2992..3378
                     /locus_tag="J8S10_001786"
     CDS             2992..3378
                     /locus_tag="J8S10_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630370.1"
                     /translation="MIPRFRSWYTPFKGKTIGQEMKYGQAGRLITHAEMAPDKYVLMQ
                     STGLKDKNGVEIFEGDVVLVNVSNGFDHLVNEKTVVQESEFHSGLVCKSLISGMEYRI
                     FSHQKMGYEYEVTGNIHENSELLEVE"
     gene            3375..3710
                     /locus_tag="J8S10_001787"
     CDS             3375..3710
                     /locus_tag="J8S10_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630371.1"
                     /translation="MIILATDYIDSLKDENGNVPALLNCGIKSKNRIILLRISADLAK
                     YLYLSKTAVYYTAATRYQYKGKTISQDYYDRLISPDIHGKSKSAIKLFGAIEIYADDF
                     PNLWLKEEQ"
     gene            3856..4425
                     /locus_tag="J8S10_001788"
     CDS             3856..4425
                     /locus_tag="J8S10_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HAZ9630372.1"
                     /translation="MNKQEAIKKLESIKVIGNDALAACYNESINAGITLMKKIDEPKK
                     LVIPQLVAGWLEKSTDPFTKAEKIAYLIKSKDGDSYYFCDWFVRDGIVTQEQGEELLA
                     WATRQSYETLLSLYNGYEVEKEPLYSVIIAGEYLVKEISCSNEVKLVSTAYLPQYLAH
                     HYQLTEKQIKAIDERYWPFAVPVEEVAEG"
     gene            4592..4897
                     /locus_tag="J8S10_001789"
     CDS             4592..4897
                     /locus_tag="J8S10_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630373.1"
                     /translation="MNVQVYLKRDLARFPRSWDTNSHPSEAEEEGYLMSANMIEITRD
                     DADEFDKKRSWYSVPNPMYTAVIEDYHISDRFILIDLERPKKRIKQYRRCGFSTKKW"
     gene            4921..5118
                     /locus_tag="J8S10_001790"
     CDS             4921..5118
                     /locus_tag="J8S10_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HAZ9630374.1"
                     /translation="MNNRHRRVAKLRNQELNVAKVKFEREYGVSAEETYKVASQCVAD
                     ASDAIRKFGISILDIKWEDTE"
     gene            5115..5321
                     /locus_tag="J8S10_001791"
     CDS             5115..5321
                     /locus_tag="J8S10_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630375.1"
                     /translation="MKIYVVKFGNQFYRSDERSIGANTLSIVDILQSARWFDNLEEAN
                     QVSRRLGGLTQVYELVTVDHEGVE"
     gene            5321..5617
                     /locus_tag="J8S10_001792"
     CDS             5321..5617
                     /locus_tag="J8S10_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630376.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTREKPKFKVGDMVRCEA
                     EGFIYPFRGYVEKVLSNSAIIRIENTMECDKWLAKSKENLAVARLVDMEVIESK"
     gene            5693..6106
                     /locus_tag="J8S10_001793"
     CDS             5693..6106
                     /locus_tag="J8S10_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HAZ9630377.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIEAERDAILAALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGRIIAYK"
     gene            6983..7327
                     /locus_tag="J8S10_001794"
     CDS             6983..7327
                     /locus_tag="J8S10_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HAZ9630378.1"
                     /translation="MTEEFYRWLLQLIREDRLVKFYQSPKWRRLREKAMKRDHYECQE
                     CRRLGKYHRVENVHHIKEVKDRPDLALDLDNLICLCVEHHNEVHGRYLTALDKQEKKI
                     ESFANFDASERW"
     gene            7332..7613
                     /locus_tag="J8S10_001795"
     CDS             7332..7613
                     /locus_tag="J8S10_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630379.1"
                     /translation="MIINDNGREYDTEKIEEYSSYTQGLIKRLIYVRYVGIRDLLSDN
                     CCSKYKVNQVREALNKDNNVERIKNVFGYSIEEINYYIDFAEAFIPMVR"
     gene            7716..8030
                     /locus_tag="J8S10_001796"
     CDS             7716..8030
                     /locus_tag="J8S10_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HAZ9630380.1"
                     /translation="MFKNELSQNRYREKLRRSLISQLESQKTNIEPFLDNVDRYISLW
                     ETAISLEEDISENGIRLENGKKNESVALLVSVNKQMGLMLDKLAITPELVGEANESIP
                     EL"
     gene            8008..9702
                     /locus_tag="J8S10_001797"
     CDS             8008..9702
                     /locus_tag="J8S10_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HAZ9630381.1"
                     /translation="MNQFLSYKHIENWFKAIEEGTIKVCKEQLLLKNYLEERVFTRED
                     IYFDKQMVEDSINIPAQYFPFELIPWEKFLQCFIYGVRWKKDKTLVFNRYLSLMGRGN
                     GKTGFASWNNFFLLTAKHGIKNYDIDIYANNESQAKTSFDDVFKVIKDHPDLDKKVFK
                     ATKEVIQNIATNSKLRYNTANARTKDGKRPGANRFDEIHENEDYSMINVATSGGGKIR
                     DYREFYDTTNGHVRGGPLDDIIEESKMILSGELGIDKDGAEFSSLFPFICRLDNDNEV
                     DDPDMWEKACPTINYNADLKRKMFQEYSQMQRNAGLRLTFMTKRMNRPMEDTRFAVAS
                     YDDVLHTKEKEFPEKMDEVIGTVDFADRRDFASVGLLGKYDKDVYFTQHTFIHESALR
                     LQNIKREVIDISIDQGKSQIVHGKNIEADYIVGWFLEMSNKYYIKKIAMDMYRAKILK
                     PALEEAGFTVEIVRSGSVTHGMLKDLVDDLFINQRLFFGDDAIMRWYCMNVYEEHISN
                     GNIRYEKIEPETRKTDGFFSFLHGLNFLDDIYDSAPVTVTNSSVENTGTGFTPLVF"
     gene            9722..10900
                     /locus_tag="J8S10_001798"
     CDS             9722..10900
                     /locus_tag="J8S10_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAZ9630382.1"
                     /translation="MGIFQKAVGYFTKKATVPLEEYFCKLQVDFVYRKFAIETCIDLI
                     ANAMSKAEFKSYEDGKNKKNDLYYRLNVAPNKKNNATEFRKKLIRRLIFYNEVLIVSP
                     SNNSSEIFIADSWDVTEYALKDDVFSQVQINNIVLDREFLESDVIYIKYADQQIRQLV
                     DAYYQAYGKLISSAMNVYKRSNARRYVLKGNLFRPQDNTTQDQINKMMTSQFKAFMEA
                     DNAGAVFQLQNEYTLEDFSGNFQSNSRDIKNLIDDIFEMTAAAFHVPKNLLKGDMSGL
                     SDQVDAFLMFEIIPIAELIQDAFNASLYEVEEYLSGNFVRVDTTMIKITSFKDLVDAI
                     DVGIRNGVFTINEGRERVGNDRSDKAMADEIFITKNNQQVSKGGEANDDNENISSSKE
                     "
     gene            10863..11549
                     /locus_tag="J8S10_001799"
     CDS             10863..11549
                     /locus_tag="J8S10_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HAZ9630383.1"
                     /translation="MTTMKTFLAVKNEGAVPQIFIQGFIGSSWFFEGNTDKGIKNILD
                     SLGDQEEIEVVINSNGGDVFQGIAIGNLLKSNKAKVNVVINGLAASAASIIAMAGDTI
                     KIYNNAQLMIHRASTYGEGNVDDFRTIADQLESIDKSVKASYKTRFNGTDEALQELLE
                     KESFMDAETALSYGLVDEIIDAENSSGTEAKKEQSVEEILNDVKEKRAEKIAAFTAAL
                     NKTFGQGDVK"
     gene            11549..12709
                     /locus_tag="J8S10_001800"
     CDS             11549..12709
                     /locus_tag="J8S10_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HAZ9630384.1"
                     /translation="MTVKNLKGVTAASDQLMKAFKDGNEESFSAAMVSLSKEIQDKIL
                     EEATAKNQDQLVLMNRGQRVLTTQETKFYNEVVKNEGFAGVEELVPATVFERVFEDLE
                     QSHPLLQKITFVNTTGVTEWIVSRGVNPAWWGKLCEAVKKVLDNDFDVINMKQFKLSG
                     YIPVCKAMLDLGPVWLDRYVRTVLVESLRIALEQAIVDGTGKDMPVGMMRDMSKQTSG
                     EYAEKKAEPITALDAVTMGGLMARLSKFNIEGVNDPIYRNVNPSDVVLIVNPTDYWSK
                     VFPAKTVLTANGEYVQVLPVPVSDLQSTAVPEGKAVIGVASDYFMGVGSTLKIEASDE
                     YHFVEDERIYLAKQYANGQPKRNDSFIVLDISALGTTTTTTKPTTTTTTTQA"
     gene            12719..13594
                     /locus_tag="J8S10_001801"
     CDS             12719..13594
                     /locus_tag="J8S10_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630385.1"
                     /translation="MKYILCQPAINRFKWELEVCLTNLKKLGIKDIVLLFSRHDDQIP
                     IFFEKEYGVEVHVYDDLRDDKEYIPSIKPYLWWKYLEEDHSREDDRYFYIDSDVIFNK
                     RINLRKLPSKDDVWYCSDCCSYLSLDYIRSCENGENILKDMANIVNVTVESLETINTN
                     SGGAQWVINRPKANYWKKVYLDSNRLYRYLRGQKTNIKIWTAEMWAQLWNMMYFNIGP
                     KVHEELDFCFATDPIEKVKEVKILHNAGVTTNDEDLFFKGRYVTSTPFDEDLSFVNKK
                     KCSYAYVKAIKAVVR"
     gene            13591..13902
                     /locus_tag="J8S10_001802"
     CDS             13591..13902
                     /locus_tag="J8S10_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630386.1"
                     /translation="MTPEQVTEELLIAVKDNIYVTWNEEDESIKKMIAKNAVYLQSKV
                     STTLSFSPESLEYGLLIERCRYDWNRALDEFEQNFASELLGFIQHYALQEYIAGDVNG
                     E"
     gene            13892..14245
                     /locus_tag="J8S10_001803"
     CDS             13892..14245
                     /locus_tag="J8S10_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HAZ9630387.1"
                     /translation="MANNRRLEETFNDGWLKILTQTTKRNELGKKIGVEDTEITSLKF
                     RNLSMRDSDITAMDAMGSKLTKKVKTPFHPIAKKFNKDQYFIVIDSMRYNVIYADYDN
                     FYIYFYLESVGEYGD"
     gene            14235..14636
                     /locus_tag="J8S10_001804"
     CDS             14235..14636
                     /locus_tag="J8S10_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630388.1"
                     /translation="MVIDNSKEKERLNKQISAIKTSLEEHFGLKLFQDSVGEDELPDD
                     FNYFILETGEIEMITEPKYSVGQNLYLTFYSENREDLTGDSLDIISLIQNRSIRFQRM
                     DPNHLKLENQDRYIDQLVFTFRRLLKSDCHG"
     gene            14629..15033
                     /locus_tag="J8S10_001805"
     CDS             14629..15033
                     /locus_tag="J8S10_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630389.1"
                     /translation="MAKNSWELKINGHDELLVRMERYSSESERLINEALKSKGSAIAV
                     DRITEKIPVSEADLRRGHQHAKNSRPLKTQYINLGFIIRPTRKFEYLKYPDLGIGTSK
                     RNQPDEFMRRGLGLALDPITELLIRQFDKLNK"
     gene            15045..15650
                     /locus_tag="J8S10_001806"
     CDS             15045..15650
                     /locus_tag="J8S10_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAZ9630390.1"
                     /translation="MAKTTTVTTFDNISIKRISFNFKNATNAISTDCNGQLDGETEMQ
                     RIVKKCGSTEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDERIKSGIYSYGPDSVG
                     EDFSLAAEIVDDFEEKNKLIGMLACTSNTGLTFSIENGADEVAALELETKVMQDEFGK
                     FYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVTNTATQSQ"
     gene            15670..16032
                     /locus_tag="J8S10_001807"
     CDS             15670..16032
                     /locus_tag="J8S10_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630391.1"
                     /translation="MNEDYSKIELNDGTILNLEPKLNIKKLLMINRDFNTDEFAKMTV
                     GKGSMDISVIQGAKAVYIAYRQANMTDYISFDEFIDKWDFDMATASYIYQLMMFKQAR
                     DAYQKEFEKANKEKKLQK"
     gene            16035..16217
                     /locus_tag="J8S10_001808"
     CDS             16035..16217
                     /locus_tag="J8S10_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630392.1"
                     /translation="MPKLLVETWVDVYSMLTDVFSMPSDLVLSDICLDDILQMAYNKS
                     AYEGWKNYAINQSQKN"
     gene            16234..19653
                     /locus_tag="J8S10_001809"
     CDS             16234..19653
                     /locus_tag="J8S10_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HAZ9630393.1"
                     /translation="MAKKRTEAEVTFIANDDGLKSTLKEISAELTKNRAELKLEQAQL
                     QQTGSESDKLGSKLSSLEKQYELQSQKVEVTSQRLANAKKYYGENSTEVQKLERELIN
                     QQTAQQRLSNEIDKTSNALAQAKGEIQTYESTMQQLDSEQKNVQASASLIESEYKKWQ
                     ATAGQSASESEKLAKAQEYVSQQSENAEKTIDILRRQLEATQSEFGATSTEAMQMEAK
                     LNDAEREFEELGQAAKNVDTTNLDDIGSKIDMNNLMEASDVLSDIGDKLTELGKQAVD
                     SANSVGSSQSKIQANFGLTKQEAEELTNVARDIYYKGFGESLDQSTDALILVKRNLGD
                     LNNQDLQNITEQAMVLENTMGADMDETLRGVNGLMVNFGLSAQDAMDLMVSGTQNGLD
                     KTHELGDNMAEYSQLWSQMGYSADETFGMLQNGLDAGAYNLDKVNDLVKEMGISLTDG
                     RFEQNMDMFSESTRKAFEEWKNGGGTQKDVINSMIQDFSNMDGQYDQLNKASTIWSAL
                     GEDNAMKVVQSLTDVNHTFDDVSGSAQKMNEDSTTPLQELNGKIAELKDSLAPIGNTI
                     IDALEPVIDFLGKMADAFNNLPQPVQDYAVAIGGLTAAFTLLMPIIVGFMALGGPTTL
                     IIGAVITVIAGVIAIIKNWGAITDWFKGIWSKFTDWLGGTWESIKEGASSVWDGVKET
                     WSGFVDWVQDIWQGVSDWFGELWSGLVEGASNIWQGVQETWQAFVDWVSNIWNGVKEV
                     WSIIWADIVGIVQIPWTLITSLIQAGINIIVGIFDVAGQLLGAAWQAVWTPISDFLKN
                     TWDTMTQWVSIAWNGIVTTFHTIFDPVVAWWNGIWTAISTTASNIWNSISATASSIWN
                     SIKNTITSLVQAAATVIQNIWSTVSSWLGGIWNSISSTASNIWNSVTSSISNAINAAK
                     SAIQSVWNSISSWISGIWNGIKNTALNLWNGITSTISSKVNDGKNAISSGWSNLTGIV
                     SDIFNNVKSTIANIWEGIKKTVSAPIDWIRDKISSIFDNLNISIPHIPLPHFKLSGEF
                     NPLKGKIPTLGVDWYAKGSVFNSPNIIGVGEAGPEAVLPLKRSVLQEIGDRILSSTSV
                     SSRAQTIQPVNNYEFNFTIDGNADEVTMKQTTQQIIDSITKVQNDNASAWR"
     gene            19704..20441
                     /locus_tag="J8S10_001810"
     CDS             19704..20441
                     /locus_tag="J8S10_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAZ9630394.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLVQDYSFEDMSFTLHYNYLEDVEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNVYYVI
                     QTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFNLLNNSLEESFPKI
                     IITPSATSCQFILNDYVFSFEGLVVGTDVVIDSDLMLCYEEQSDGDILDRSNKMKTMQ
                     YPTLQVDINYFNCTGLSKIQIYRNGLR"
     gene            20451..22742
                     /locus_tag="J8S10_001811"
     CDS             20451..22742
                     /locus_tag="J8S10_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630395.1"
                     /translation="MIDNLITIYDKNDANNLAEHLYDTQGLGALSDWLTATVSNKLNG
                     AEIFQGTYPISGTNADLIVEGRIIQCYVDENRAKQRLRIYYAKTSVIGNTIEVKAEPI
                     FNDIRKSVLNKYDSGTEKITASQAWQNAKTLAKPVIPSQFSFSSLVDTLANVKIEKAN
                     FLEFFGGKEGSILDRFHGEFLKDNNTLRHEKRLGTDHKIKAIYTKNLTGLDLEIDAQS
                     VLVGVYPFISSSSEGEDEITLPEEVIFTDYVDDYPAGYVSFVDFKDKATDVATLREAA
                     KDWLKTNIDKQKPQVSGSIELVPLRHQRGYEKFVDLEKVSMGDGVDVYHPQLKVNMSA
                     RIVEYTFNVLTNSYDKLVVGNVKTNFLENTENNVSNLINDAIDQLKNGGEISDLLNDI
                     VDHQTDMITGQNGGYVLLDPKEAPSRILIMDTPDKNTARNVLQINNAGIGFSKTGING
                     TYETAWTLDGGFNASFITAGEIVGITIRGTTLISDGADYRTSIANGKMTWYSKKVNKD
                     IMELEARDYVSADAGIVSYTMKTGGGFMIRNPQGNLVFSTWDNGNNRPFLSFGAPNFR
                     YSNASYVTSGDGSSLSINGSAGNSWEFKVAGRTMKFTSDGMLTLPGCFFGSWEDGKLA
                     RFEQSTVQVYKDFTVRGTKNSTVPTEHYGQRLLNAYETPEYYFADYGEAVTGDDGKVR
                     VDIDPMFAETVNLSRYMTHVTPTELVLCAVTHEDIDHFIIETSKPNVLVRWNLVAHRL
                     GYEDIRLKEDTAYDSTVLDQKRF"
     gene            22766..>23373
                     /locus_tag="J8S10_001812"
     CDS             22766..>23373
                     /locus_tag="J8S10_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630396.1"
                     /translation="MASSLYNLALDFSKELNYTKAIMARQGDKGITVTVKPFLNGLQM
                     DTSGGTFTLKGTTPSNRYVDSVATSVTSEEVIFSLDGTFMSEAGYYKHCYVEYRKGNQ
                     ILTTQDIIFFSLGVSDISQGQADEYVSQLEELIRKYNETFDAFMAEIKGRVDSLNQQI
                     TDLTGQAKTLQDKLDALKEEISKLGNLQVMYSNSIDFGGYDYS"
BASE COUNT         8396 a         3422 c         5037 g         6518 t
ORIGIN      
        1 cagagtacac atttgcagca ctctgcagaa tccatcacac agagaaacac aaaataggtg
       61 tgatcaattt caaaaataaa tatcaaatca aagggatcaa gttaaaccag gaaacaatta
      121 aaaagttaag gataggagga taaatttggc tgagataagt tggatcaaac ttaaaactac
      181 tatgtttgac gatgaaaaaa tacgattaat ccaagctgtt cctgagtcgg atgccatcat
      241 cgttatatgg attcgattac tagttttagc aggaaagact aacgacgatg gtctgatata
      301 tatccagagg aacatgcctt ataccgaaga aatgcttgct acattgtttg gcaaaaacgt
      361 aaatacggtt cgcttagcgc taactacatt ggcaaatttc aacatgattg atctaagcag
      421 tgatggacta attgccatca gtaattggga aaaacatcaa aatatcgagg gtatggataa
      481 agtaaggcta aaaaatgctg aaagaaaccg taaatacagg gaaagaaaga gacaggaacg
      541 tctcaaattg gaaaatgacg ttagcgtgac gtcacgtgac ggtacagata aagatataga
      601 agaagataaa gatatagata aagaagaaaa gaaaggtaag tattctgacg aacacttacg
      661 ccttgctaaa aagttgcaaa gtaatttaac tgaagatttt ccaaaagaaa tgaacaaagt
      721 agatatcgaa aaatgggcag acacaatcag gttgatggaa gaaagagata aagcatctat
      781 agaagcgatt gagtatgtga tcaattggct acctacaaat gaattttggt ttggaaatat
      841 tagaagtgct aagaaattga gagaaaaatt tgagaagctc aaattcgaaa tcaaagcaga
      901 caagaagaat cataaaaagc aaagtcaaaa actacagtac agcaatccta gtgaatatga
      961 cgacttgcca atttaaaaag gagatgcatc acatggaaag cctagcaaat gctatggaga
     1021 aactaataag aagagtatta gtgcaaagcg gaaaatgtcc agaatgtagc gaacctttgt
     1081 atagttggcg agctaaaaat aaggatggtt cagaacgttg taaaccaaca tgcatgagtt
     1141 gtggttataa agcgttacgt gtgaaagagg atatacagac cgaacggata tataacgata
     1201 gcttaaaagc acgagcgttg agtttttttc aaaatggttc ggtattaaca gataaaactt
     1261 tgtttaaatg caaaatggaa aattatcacg tagtggatca agaaacaaaa atcgctttag
     1321 aaaaagcaaa aagctatacg aatgaggttc tgctgaacca tcctgcacat ttcattctat
     1381 cagggaaatc aggaagcgga aaaagccact tatcaatggc cacagcttgg gaaatacttg
     1441 agcgctcaaa ttatgacaag aaaatacttt ttataagcta tcaagaatta ttagagcaaa
     1501 taaagttttc ttataacaat actgaactga gaaaagaaat tgaaggatcg cttatagccg
     1561 atattaaaac aactgatttg gtggtttttg acgatattgg agctgaatta ggtagtgggg
     1621 tatcaaatag taggcagttt acaaacaaca cgttaaacac gctcttagaa gccagacaga
     1681 acaaggcaac gatcatcaca acaaacttat ctggtcctga actaagagaa gcctacggtg
     1741 aaagaattgt ttctaggata tttaagaatt cagaaggtta tgcgctgaaa ttccaacaaa
     1801 cagcagacaa gcgcataaaa ccagtgaaag gtagtatcgc atgaataaat accgtaataa
     1861 aaaaactgtt catcgaggta tcaagtttga ttctatcgca gaagcagagt attacgatct
     1921 agccttgtgg caagctgaag caaatggctg gaaagtaaaa cttcaggaaa gatttgagct
     1981 gatgccgaaa tttgaactag acggaaagaa gtatcgcaag atcgagtata ttcccgactt
     2041 cacattttat aaaaacggca aacttgtcaa agtcgtagat gtcaaaggaa tgcagacaaa
     2101 agactttaag atcaaggcaa agttgttctg tcatcaatat caagcgccgt tgatattagc
     2161 taaaaaatat cggaatacgt tcaaggaaga gcgtttttaa cgaggtggtc catcatgaca
     2221 acagaagaag tgattcaaat gcgaattcga agcattcaac gtgaaattga cgatctagaa
     2281 cgaacaaagg cagtgatggt caatgaaacg gcgagaaagg caatcgattt gcacatagag
     2341 aatttaagaa gggaaattcg tagattggag gaataaacgt ggataagaaa gcaacaatga
     2401 aacgaattgt tgaattaacc aagtcagaat cttggcaaga agacaaagaa atagttgcag
     2461 aagtccaaag gatcggcaaa tcaatgtgga ctgaaaagcc caaacggaga acgccaagaa
     2521 aaattgcaat ctggcatggt gatcgaattc tagtaacagg tactgctgaa cagttatctg
     2581 aaattactgg attaagcaaa aacatcatct gggatagagc taggagctta tggattgatt
     2641 caaaaggacg acagtttagg tatgtggagg agaaataatg gatctcatta cacaatatag
     2701 tgatatcatc ctcaagaaaa tcatgatgaa gattcagaaa gacaaaaaat caaaagaacg
     2761 agcggaatta gttaagttgg aaatggctga aacaggagca ggagtgcgaa gtagcaggca
     2821 ttggaaagca gcagcaaaca ttgaatttta ttacaacgaa attcaaaaag ggttcgatca
     2881 gatgcgtgag ctggatcggc aaacaaattg gagcaagaaa cttcatcaag atcgtttcaa
     2941 atttgtagag aaatataaag agatattaga cgaatacatg gagggcagca aatgataccg
     3001 agatttcgat cgtggtacac accatttaaa ggtaaaacaa ttggacaaga aatgaaatat
     3061 gggcaagcag gaaggttgat cactcatgct gaaatggctc cagataaata tgtgcttatg
     3121 caatccacag gactgaaaga taagaatggc gtagaaatat ttgaagggga tgtagttctg
     3181 gttaatgtaa gtaatggttt tgatcattta gttaatgaaa aaacggttgt acaagaatcc
     3241 gagtttcatt ccggattagt ttgtaaatca ttaattagtg gaatggaata tagaatattc
     3301 agccaccaaa agatgggata cgaatatgaa gtcaccggaa atatacacga gaatagcgag
     3361 ttattggagg tagagtgatt atcttagcta ctgactacat cgattcttta aaagatgaaa
     3421 atgggaatgt cccagcattg ctaaattgtg gaattaaaag taagaataga atcattttgt
     3481 tacggatatc ggctgattta gcaaaatatc tttatctgag caagacagca gtatattaca
     3541 ctgcggctac acgttatcag tacaagggaa aaacaatcag tcaggattat tatgatcgtt
     3601 taatcagtcc tgacatacat ggaaaatcaa aatcagcgat caagttattt ggcgcaatag
     3661 agatatatgc cgatgatttt ccaaatttat ggttgaagga ggaacagtaa tgaaagactg
     3721 gttagaagaa gcaagcgcct tagttggctg tttcataaac tgtgcgttta tatctgtaat
     3781 tattgcactg gtgggatttg tatcattgaa agtgattata ttgctttggc agttaatttt
     3841 ttaggaggaa cagcgatgaa taaacaggaa gcaatcaaaa agttagaaag tattaaagtg
     3901 ataggaaatg atgcactagc tgcttgctat aacgagagta taaatgcagg tattacgtta
     3961 atgaaaaaaa tagacgaacc gaagaagcta gttattccac aactcgtggc cggttggctt
     4021 gagaaatcta cggacccttt tacgaaagct gaaaaaatag cgtatttaat caaatctaaa
     4081 gatggtgatt catattattt ctgtgattgg tttgtacgag atggcatagt gacgcaagaa
     4141 caaggagaag aattactcgc ttgggcaacg agacaatcat atgaaacact attgagcttg
     4201 tacaacggct acgaggtcga gaaagagccg ttgtacagtg taataattgc tggcgagtac
     4261 cttgtcaagg agatcagttg cagtaatgaa gttaaactag tatcaacagc ttacctgcca
     4321 caataccttg cacaccacta ccaactgacc gaaaaacaga tcaaagcaat tgatgaaaga
     4381 tactggccat ttgctgtgcc agtggaagag gtggcggaag gatgagtaga cagataatgc
     4441 tccatatacc agacggaaca aaggcaatga cgattaccat tgttgctgca caaaaagacg
     4501 gtgggttggc gttgaaaaca aaaagcattg ataccaaaca gattttagaa ggcagagatg
     4561 tcgagataga gatcgatgag gaggaagcgg aatgaatgtt caagtttatt taaaaagaga
     4621 tttggccagg tttcctcgaa gctgggatac aaattcccac ccatccgagg cagaagaaga
     4681 gggctatcta atgtctgcta acatgataga aattacaaga gatgatgcgg atgagtttga
     4741 taaaaaaaga tcatggtact cggttccgaa tccaatgtat acggctgtaa tagaagatta
     4801 tcatatatcc gacagattta ttctgattga tctagaaagg cctaagaaac gaattaaaca
     4861 gtatagacgt tgtggatttt caacaaagaa atggtgataa caaaacagag gtgaagaaaa
     4921 atgaacaaca gacaccgcag agtagcaaaa ctaagaaatc aagaactgaa tgtagcgaaa
     4981 gtaaagttcg aacgggagta tggtgtttct gcagaagaaa catataaagt ggcaagtcag
     5041 tgtgttgctg atgcaagtga tgctattcgt aagtttggaa tttcgatact agatattaaa
     5101 tgggaggata cagaatgaag atttatgtag taaagtttgg aaatcaattt tacagaagcg
     5161 atgaacgttc tataggggct aacacattat ccattgtaga catactccaa agcgcaagat
     5221 ggtttgataa tctcgaagaa gctaaccaag tttcacgacg acttggtgga ttaacgcaag
     5281 tatatgaact ggtcactgtc gatcatgagg gggtagagta atgaaactaa aagacggatt
     5341 ttacgctagt agtcatggta tcggcggttt gatgctagat atgccgacaa agaaccctaa
     5401 aacacgtgag aaaccaaaat tcaaagtcgg tgacatggtt cgctgtgaag cagaaggatt
     5461 tatctatcca tttcgtggat atgtagaaaa ggtattgtcg aactcagcaa tcattcgtat
     5521 tgaaaacacg atggaatgtg acaagtggtt agcgaaaagc aaagagaatt tagctgtagc
     5581 gagattagtt gacatggaag taatcgagag caaataaaaa agccggatcg ctccgactaa
     5641 cataataaaa cagacaagtt tattatatca cataaaggag cggtttgact tgatgcaatt
     5701 gttacgagag gtagatttca aacagacaag atgtaatgcg agagatgtgc tgaagaactt
     5761 tcggcgtttg gagcggatgg caggtcgctc tttgatagat attaagtctc caattattac
     5821 ggatatgccg aaggcgccga agcacggcaa taaggcagag gacgcgatca ttcagatgat
     5881 ggatatagaa gcagagagag atgcgatttt agcggctttg atggctctta gtctgattag
     5941 ccgtcagata ctctactaca gcttttgtgt gccagatagc ttctcaaact acagaattag
     6001 ccgtgaagtg ggttattcag aaagaagtat acaacggatg aagtcggaag ctctaataga
     6061 gtttgcagaa gcatataaac acggaagaat aattgcttat aaataatttg gcggtttttt
     6121 ggcggaatga tggcggtttt tagctattta ccagtgatat tatggtagtg tcgaaagatt
     6181 agtgataggt ctgagacaaa ataataataa aaggaacatc gttttattat tgtttcacaa
     6241 ttaagcttcg atagacagca acggaaatat taagaataag gatgtgaatt tcaactcctt
     6301 ctaaattgtt cttattatct atcatccgtt gctgtctatt gtttttttaa ttattcacac
     6361 gataactaaa ggtgagtgaa gagaaatgat tccattaata atttcaattt ttgcgctctg
     6421 tcttaatgtc tatatgattg gatttaaaaa tgggcaaaat aaaaaatagt agcagccaag
     6481 aataatttta tagtgtcact gtggcggaaa gggtagacgc ttaaaaataa ggtcaatacg
     6541 tcgagggata gccttaacgt tttatgattt gaccatgcaa tgttcgattc attgccagtg
     6601 actttggcaa ccgagggttg gaaatgggcg ctcaaagtac acgagcaagg cgaggtcgat
     6661 agtaatcgat ggaatcggtg taggttgctt gatagagcta taactgcatc tcgtttatga
     6721 ggtgtagttt ttacagatta gatcactctt tgagtggtct ttttatttta cacaaaggag
     6781 gtaacaagaa tgtatagacc acaatactta gaacagaagt atgaagtaat cactgtgcaa
     6841 aacggtaacg gtgagatagt acgaaagtat agaagaccaa taaagagcga tacatacaaa
     6901 cgaaaggaaa gcaatgaagt tattccattg tatggcaaaa gaatagctaa gcattaaata
     6961 agattgcgaa aggagacgga atatgaccga ggaattctat agatggctat tacagttgat
     7021 aagagaagat cgtttagtta agttctatca gtctcctaaa tggcgcaggc ttagagagaa
     7081 agcgatgaaa cgagatcact atgaatgcca agagtgtaga agactaggta agtatcatag
     7141 agtagaaaac gttcatcata taaaggaagt caaggataga cctgacttag ctttagattt
     7201 agataatctt atttgtttat gtgttgaaca tcataatgaa gttcatggca gatatcttac
     7261 agcattagat aaacaagaga agaagataga aagctttgct aacttcgatg caagtgaaag
     7321 gtggtaagtg catgatcatc aatgataatg gcagagagta tgatacagaa aagattgaag
     7381 agtattcatc ttatactcag ggattaatta aacgtttgat atacgttcgc tatgtaggta
     7441 ttagggatct gttatcagat aactgttgta gtaaatacaa agtgaatcaa gtaagagaag
     7501 cgttgaataa agataataac gtcgaaagaa taaaaaatgt ttttggatat agtattgaag
     7561 agattaatta ttacattgac ttcgctgaag ctttcattcc gatggtgaga taaccccccc
     7621 ttaaaataaa tcgcaaattt tttgggggtg atgaaacgga gggggctgtc aggaaaagag
     7681 attttttcga actttatcat gaaaggaggg ctaaaatgtt taaaaacgaa ttgtctcaaa
     7741 atcgctacag agaaaaatta cgccgctctt taataagcca attggaaagt cagaaaacaa
     7801 atattgagcc attcttagat aatgttgatc gttatatcag tttatgggaa acggcgatat
     7861 cactggaaga agatatatcc gagaacggca ttagactgga gaatggtaaa aagaatgaat
     7921 cagtagcgtt gcttgtttct gtcaacaaac aaatgggatt gatgttggat aaacttgcca
     7981 ttactcctga attggtaggt gaagcaaatg aatcaattcc tgagttataa gcatattgaa
     8041 aattggttca aagctataga agaaggcact atcaaggtat gcaaagagca attattgcta
     8101 aaaaattatc tagaagaaag agtctttact agagaagata tttacttcga taagcagatg
     8161 gtagaggatt caatcaatat accagcacaa tactttccat tcgaattaat tccgtgggaa
     8221 aaatttctac aatgttttat ttatggtgtt cgatggaaaa aagataaaac actagtgttc
     8281 aatagatatc tttcattaat gggacgtggt aatggtaaaa ctggttttgc ttcttggaac
     8341 aacttctttc tactaaccgc taaacacggt attaaaaatt atgatattga tatctatgcc
     8401 aataatgaaa gccaagcaaa gactagtttt gatgatgtat ttaaagtaat taaagatcat
     8461 cctgatttag ataaaaaagt atttaaagct acgaaggaag ttattcaaaa tatcgctaca
     8521 aacagcaaac ttcgttataa cacggcaaat gctagaacaa aagatgggaa gcgaccaggt
     8581 gcaaaccgct ttgatgaaat tcacgaaaat gaagattatt caatgataaa tgtggctact
     8641 tctggtggtg gtaaaattcg agattataga gaattttatg atacaactaa tggtcatgtt
     8701 cgtggtggtc cgcttgatga cattatagaa gaatcaaaaa tgattctttc tggagaactt
     8761 ggaattgaca aggatggagc agaattttct agtttgtttc catttatttg tcgcttggat
     8821 aacgataatg aagttgatga tcccgacatg tgggaaaaag cttgtccaac tattaattac
     8881 aatgcagatt taaaacggaa aatgtttcaa gaatactctc aaatgcaacg taatgctggt
     8941 ttaagactta cgttcatgac caaacgaatg aacagaccta tggaagatac acgatttgct
     9001 gttgcttcat atgatgatgt tctgcatacg aaagaaaaag aatttcctga aaaaatggat
     9061 gaagtgatag gaacagtcga ttttgctgat agacgagatt ttgccagcgt tgggttgcta
     9121 ggaaaatacg ataaagatgt ttattttaca caacatactt ttatccacga atcagccctt
     9181 cgattacaaa acatcaaacg agaggttata gatatttcta tagatcaagg aaaatcacag
     9241 atcgttcatg gaaaaaatat agaagctgat tatattgtag gttggtttct tgaaatgagt
     9301 aataaatatt atattaaaaa aatcgctatg gatatgtacc gtgcaaaaat attgaagccc
     9361 gctttagaag aagcaggttt tactgtggaa attgttcgaa gcggatctgt tacacatggt
     9421 atgttaaaag atctggttga tgaccttttt attaatcaac gtttattttt tggtgacgat
     9481 gcgattatgc gttggtattg catgaatgta tatgaagagc atatttctaa tggaaatata
     9541 cgctatgaaa aaatagaacc tgaaactaga aaaacggatg gctttttttc attccttcat
     9601 ggtttgaatt ttttagatga tatttatgat tctgctcctg taacagtcac aaatagctca
     9661 gtagaaaata caggaactgg atttactcct ctagtattct aacttgaaag gaggtgagaa
     9721 agtggggatt tttcaaaagg cggtaggata cttcacaaaa aaagcaacgg ttcctttaga
     9781 agaatacttt tgtaaattgc aagttgattt tgtgtatcga aaatttgcga ttgaaacttg
     9841 tattgatttg attgcaaatg cgatgagtaa agcggaattc aagtcatatg aagatggaaa
     9901 aaataaaaag aatgatcttt actataggct gaatgtagct cctaataaga aaaataatgc
     9961 aacagaattt agaaaaaaac tgatcaggag attaatattc tacaatgaag tattgatcgt
    10021 ttctccgtct aataattcta gcgaaatatt tattgcggat agttgggatg tcacagaata
    10081 tgcattgaaa gatgatgtgt tttctcaagt gcaaattaac aacatagtcc ttgatagaga
    10141 atttctagaa agtgatgtta tctatataaa atacgcagat caacaaatta ggcaactagt
    10201 cgatgcgtat tatcaagcgt atgggaaact catttctagt gccatgaatg tttacaagcg
    10261 ctctaacgct cgtagatacg tactgaaagg gaatttattc cgaccgcaag acaatacaac
    10321 acaagatcaa atcaataaaa tgatgacatc acaatttaag gcttttatgg aagctgataa
    10381 tgcaggtgcg gtatttcaat tacaaaatga gtacacatta gaagatttca gcggaaactt
    10441 ccaaagcaat tcaagagata taaaaaactt aatagacgac atctttgaga tgacagcagc
    10501 agcgtttcac gttccgaaaa acctactaaa gggagacatg agtgggttat cggatcaagt
    10561 ggacgctttt ttaatgttcg aaatcatacc gattgctgaa cttattcagg atgcgtttaa
    10621 cgctagtctc tatgaagtag aagaatactt gtcagggaat tttgtacgtg tggatacaac
    10681 tatgatcaag attactagct tcaaagattt ggttgacgct attgatgtag gcattagaaa
    10741 tggagtattt acaatcaacg aaggaagaga gcgcgttgga aatgatcgct ctgataaggc
    10801 gatggcagat gaaatattta taactaaaaa caatcaacaa gtatcgaaag gaggtgaggc
    10861 gaatgacgac aatgaaaaca tttctagcag taaagaatga aggcgcagta ccgcaaattt
    10921 ttattcaggg atttattggt tctagttggt tctttgaagg gaatactgac aagggaatca
    10981 aaaatatttt ggatagtcta ggtgatcaag aagaaattga agtagtaatt aattcaaacg
    11041 gtggagacgt atttcaaggg attgctattg ggaacttact taagtcaaat aaagcaaaag
    11101 ttaacgttgt gattaacggc ttagccgcta gtgctgcttc aattatcgca atggctggcg
    11161 atactataaa aatctacaac aatgcacaat tgatgattca ccgcgcttcc acatacggag
    11221 aaggaaatgt cgatgacttc cgtacgattg ctgaccaact ggaatcaatt gataaatcgg
    11281 taaaggcttc atataaaaca cgattcaatg gcacagatga agcattgcaa gaacttcttg
    11341 aaaaagaatc gtttatggat gcagaaacag ctttgagtta tggattggtc gatgaaatta
    11401 tcgatgcaga aaatagctca ggtactgaag ctaaaaaaga acaaagcgtt gaagaaattt
    11461 tgaatgacgt taaagaaaaa agagcagaaa aaattgctgc atttacagca gcattaaata
    11521 aaacatttgg acaaggagat gtaaaataat gacagttaaa aatttaaaag gtgtaacagc
    11581 tgcaagcgac caattgatga aagcttttaa agatggtaac gaagaatctt ttagcgcagc
    11641 tatggtaagc ttatctaagg aaattcagga taaaatttta gaagaagcaa cagcaaaaaa
    11701 tcaagatcaa ttagtattaa tgaaccgtgg tcagcgtgta ttaactacac aagaaacaaa
    11761 attctataac gaagtagtga aaaacgaagg ttttgcaggg gtcgaagaat tagtgccagc
    11821 tactgtattt gaacgtgtat ttgaagattt agaacaatct catccactat tgcaaaaaat
    11881 tacttttgtt aacacaactg gtgtaacaga atggattgtg tcacgtggag tcaatccagc
    11941 atggtggggt aaactttgcg aagctgttaa aaaagtttta gataatgact ttgatgtaat
    12001 taacatgaag cagttcaagc tatcaggtta tattcctgta tgtaaggcaa tgcttgattt
    12061 aggtccagta tggttagatc gttatgtccg tactgtttta gtagaatcat tgagaattgc
    12121 attagaacaa gcaattgttg atggtactgg taaagatatg ccagtcggaa tgatgcgtga
    12181 catgagcaaa caaactagcg gagaatatgc tgaaaaaaaa gcagaaccta ttacagcttt
    12241 agatgctgta actatgggcg gtttgatggc gcgactatca aaattcaata tcgaaggtgt
    12301 gaatgatccg atttatcgta atgtgaatcc ttctgatgtg gtcctaattg tgaatccaac
    12361 tgattactgg tctaaagtat tcccagctaa gactgtacta actgctaatg gagaatacgt
    12421 acaagtattg ccagtaccag tttcagattt gcagtcaacg gctgtgccag aaggaaaagc
    12481 agttattggg gtagcctcag attacttcat gggtgtagga tctacactaa aaattgaagc
    12541 ttcagatgaa taccattttg ttgaagacga acgcatttat ctagctaaac aatatgcaaa
    12601 cggtcaacct aaacgtaacg atagtttcat tgtattagat attagcgctt tgggaactac
    12661 tactacaact acaaaaccaa caaccacaac aactacaaca caagcgtagg tgatcagaat
    12721 gaagtatatt ctttgtcagc cggcaatcaa tcggtttaaa tgggagcttg aagtttgttt
    12781 aactaatctg aagaaactag gaatcaaaga tatcgtattg cttttcagca gacacgatga
    12841 tcagattcct attttttttg agaaggaata tggtgttgaa gttcatgtgt acgatgatct
    12901 gcgggacgac aaagagtata ttccttcgat taaaccatat ttatggtgga aatatttaga
    12961 agaagatcat tcgcgtgagg acgaccgata tttctatatc gattcggatg tcattttcaa
    13021 taaaagaatt aatttgcgca aattgccttc taaagatgat gtttggtatt gtagcgactg
    13081 ctgtagttat ctaagtcttg attatattag aagctgtgaa aacggagaaa atattctaaa
    13141 agatatggca aacattgtaa atgttacagt agaatctttg gaaactataa acactaattc
    13201 aggaggcgca cagtgggtta ttaaccgccc taaagcgaat tattggaaaa aggtttatct
    13261 ggattctaat cggctatatc gctaccttag agggcaaaaa acaaatataa aaatctggac
    13321 agccgagatg tgggcacagc tttggaacat gatgtatttc aatattggtc ctaaagttca
    13381 cgaggaatta gacttttgtt ttgctactga tccaatagaa aaagttaaag aagtaaaaat
    13441 cttacacaat gctggagtaa caacaaacga tgaagattta tttttcaaag ggagatacgt
    13501 gacttctacg ccttttgatg aagatttatc atttgtaaac aagaaaaaat gctcttacgc
    13561 atatgttaaa gcaattaagg cggtggttag atgacgcctg aacaagtgac tgaagaattg
    13621 ctaatagctg tgaaggataa tatttacgtt acctggaacg aagaagatga gtcaattaaa
    13681 aagatgatag ctaaaaatgc tgtttatctt caaagtaaag tgagtacaac actttctttt
    13741 tctcctgaaa gcttagaata cggattgcta atcgaaagat gtagatacga ctggaatcgt
    13801 gctttagatg agtttgaaca aaatttcgct agtgagttat taggtttcat tcaacattat
    13861 gcgctacaag aatatattgc aggtgatgtg aatggcgaat aatcgtagac tcgaagaaac
    13921 attcaacgat ggttggttaa agattttgac gcaaactacc aaaagaaatg aactaggaaa
    13981 aaagattggt gtagaagata cagaaatcac ttctttaaaa tttagaaatc tttccatgag
    14041 agatagtgat ataacagcta tggatgcgat gggatcgaaa ttaactaaga aagtaaagac
    14101 tccatttcat ccaatcgcca agaaatttaa taaagatcaa tattttatcg taatcgatag
    14161 tatgcgttac aacgttatct atgccgatta cgataatttt tatatctatt tttatcttga
    14221 aagtgtgggt gaatatggtg attgataatt ctaaagaaaa agaacgttta aataagcaaa
    14281 tttctgctat caaaacttcc ttagaagagc attttggcct caaactcttt caagactccg
    14341 taggcgagga tgagctacct gatgatttta attacttcat tctcgaaaca ggagaaatag
    14401 aaatgatcac tgagccaaaa tatagcgtgg gtcaaaatct atatctaact ttctattcag
    14461 aaaatagaga agatttaaca ggagactcac tagatattat ttcattgatt caaaatcgtt
    14521 cgattcgttt tcagagaatg gatcccaatc atttaaaact agagaaccaa gatcgctata
    14581 tcgatcaatt ggtatttacg tttagacgat tattgaagag tgattgtcat ggctaaaaat
    14641 agttgggagc taaaaataaa tggacatgat gaacttcttg tgcggatgga acgctattca
    14701 agcgagagcg aacgactgat taacgaagca ttgaaatcaa aaggttcggc tattgcagtg
    14761 gataggatta cagaaaaaat tcctgtttct gaagcagatt taagaagagg gcaccaacac
    14821 gcaaaaaata gtcgtccact taagactcaa tacattaatt tgggtttcat cattagacct
    14881 acaagaaaat ttgagtattt aaaatatcct gatttgggga taggtacttc taaaagaaat
    14941 cagccggacg aatttatgag aagaggatta ggtcttgcac ttgatccaat tacagaactt
    15001 ctgattcgtc aattcgataa attaaataaa taggaggaac aacaatggct aaaacaacaa
    15061 cagtaacaac ttttgacaat ataagtatta aaagaatttc ttttaatttt aagaatgcaa
    15121 caaatgcaat ttcaactgat tgtaatggac aattagatgg cgaaacagaa atgcagagaa
    15181 ttgtaaaaaa atgcggttca acagaagtaa aatcgaaatc taaaccaatc aatatgacgg
    15241 taacaattac tgcacatgta ccgatggaag tttatcgacg cttcaatggg ttgaaacaag
    15301 atgaacgtat taaatcggga atttactctt atggtcctga ttccgtaggg gaagatttct
    15361 ctcttgctgc agagatcgtg gatgatttcg aagaaaaaaa taagctgatt ggtatgttag
    15421 catgcacttc gaatacagga ttaacattct ctattgaaaa tggtgcggat gaagtagctg
    15481 cgttagaact agaaacaaaa gttatgcaag atgaatttgg taaattttat catgaagcaa
    15541 ttgttgcaga acttgaagaa gacttaacag atcaatggat gacgaatcta tctgctgatg
    15601 tgattaaaaa aacttcagtt gtgacaaata cggccactca atcacagtaa aaaaaacgga
    15661 ggtagcgaaa tgaacgaaga ttactcaaaa attgaactaa acgatggaac aattttgaat
    15721 ttagaaccta aactgaatat caagaaatta ttgatgatca atagagattt taacacagac
    15781 gagtttgcaa aaatgactgt gggaaaagga tccatggata tttctgttat tcaaggtgca
    15841 aaggctgtgt atattgctta ccgccaagcg aacatgactg attatatttc attcgatgaa
    15901 tttatcgata aatgggattt tgatatggct actgccagct atatttatca attgatgatg
    15961 ttcaaacaag cacgcgatgc ttatcaaaaa gaatttgaaa aagcaaataa ggaaaaaaag
    16021 cttcaaaagt aaaaatgcca aagctcttag ttgaaacgtg ggtcgatgtc tattcgatgt
    16081 tgaccgacgt tttttctatg ccttcagatt tggttttaag cgatatctgt ttagatgaca
    16141 ttttgcaaat ggcttacaac aagagtgctt atgaaggatg gaaaaactat gcaataaacc
    16201 aatcccagaa aaactaaaga aaggaggtaa aaaatggcta aaaagagaac agaagcagaa
    16261 gtaacattca tagctaacga tgacggattg aaatctacgt taaaagaaat cagtgctgaa
    16321 ttaactaaaa atagagcaga attaaaacta gaacaagctc aattacaaca gactggttct
    16381 gaatcagaca agttaggaag taaattatct tctttagaaa agcagtatga attacaaagt
    16441 caaaaagttg aagtaactag ccaacgttta gccaatgcca aaaaatatta tggagaaaat
    16501 tccaccgaag ttcagaaact tgagagagaa ctgattaacc aacaaacagc gcaacaacgt
    16561 ttgtcaaacg aaattgataa aacgagtaat gcactagctc aagcaaaagg cgaaatacag
    16621 acgtacgagt ctacaatgca acagttggat agtgaacaaa aaaatgttca agctagtgct
    16681 tctctgattg aatccgaata caaaaaatgg caagcaactg ctggtcaatc agcttctgaa
    16741 tccgagaaat tagcgaaagc ccaagaatat gtttctcaac aatctgaaaa tgcagagaaa
    16801 acgatagata tcctgagacg acagttagaa gctacacagt ctgagtttgg cgctacatcc
    16861 acagaagcaa tgcagatgga ggcgaagctt aatgatgctg aacgtgaatt tgaagagtta
    16921 ggacaagctg ctaaaaatgt agatacaact aacttggacg atatcggaag caaaatagat
    16981 atgaataatc taatggaagc ttctgacgtt ttaagcgaca ttggcgataa gcttacagaa
    17041 ttagggaaac aagcagtgga ctctgctaat agtgtaggta gttcccagag taaaatacaa
    17101 gctaattttg gtttgactaa acaagaggct gaagaattaa cgaatgtagc cagagacatt
    17161 tattataaag gttttggaga atcgttagat cagtccacag atgcattgat tttggtaaag
    17221 cgtaatttag gcgatttaaa taatcaagat ttacaaaata tcacggaaca agctatggtc
    17281 ctagaaaaca ccatgggcgc tgatatggat gaaacgttac gtggtgtaaa tggcttaatg
    17341 gtcaatttcg gcttgagcgc tcaagatgca atggatttaa tggtttcggg tactcaaaac
    17401 ggtttagata aaacgcacga attaggcgac aatatggcag aatatagcca attatggagt
    17461 caaatgggat attcagctga tgaaacgttc ggaatgcttc aaaatggttt agatgcgggt
    17521 gcttataacc ttgataaagt caatgactta gttaaggaaa tgggaatatc gttaacagat
    17581 ggtcgatttg agcaaaacat ggatatgttt agtgaaagta ctagaaaagc ttttgaagag
    17641 tggaaaaatg gcggaggaac acaaaaagac gttattaatt ccatgattca agattttagc
    17701 aatatggatg gtcaatacga ccaattaaat aaagcttcta caatttggtc tgcacttggc
    17761 gaagataacg cgatgaaagt tgtccaatct ttgactgatg ttaaccatac atttgatgat
    17821 gttagtggat ctgcacaaaa aatgaatgaa gattctacta ctccgttaca agaattaaac
    17881 ggaaaaatag ctgaattaaa ggattcatta gctcctatag gcaacacaat catagatgca
    17941 ctcgaaccag taattgattt tctaggaaag atggctgatg cgtttaataa tcttccacaa
    18001 ccagtacagg attatgccgt agcgattggc ggattgactg ctgcatttac tttattaatg
    18061 ccaataatag ttggcttcat ggctctaggt ggtcctacta cattaataat aggagcagtt
    18121 attactgtta ttgctggagt tatagcaatt ataaaaaact ggggcgcaat tactgactgg
    18181 tttaagggaa tatggagtaa attcactgat tggttgggtg gtacttggga aagtataaaa
    18241 gaaggtgcct catcagtttg ggatggagtt aaagaaacct ggtctggatt tgtagattgg
    18301 gttcaagata tttggcaagg agtttctgat tggtttggag agctatggag cggattagtt
    18361 gaaggagctt ccaacatctg gcaaggagtc caagagactt ggcaagcatt cgttgattgg
    18421 gtttcaaata tttggaacgg agtcaaagaa gtatggtcga ttatttgggc agacattgta
    18481 ggaattgttc aaataccatg gaccttaata acgtcattga ttcaagccgg tattaatatt
    18541 atcgtgggta tttttgatgt agctggacag ttattaggcg cagcttggca agctgtttgg
    18601 acacctattt ctgatttcct taaaaacact tgggatacta tgacacaatg ggtaagcatc
    18661 gcttggaatg gaattgtaac tacattccat actatatttg atccagtagt ggcatggtgg
    18721 aatggtatat ggacagctat tagtactacg gcttcaaata tttggaattc aattagtgca
    18781 acagcttcta gtatttggaa cagtatcaag aatacaatca ctagcttggt acaagcagct
    18841 gctacagtaa ttcaaaatat ttggtcaact gtatctagtt ggttaggtgg aatttggaat
    18901 tcaatcagct ctacagcatc aaatatctgg aatagcgtga ctagtagtat aagcaatgct
    18961 ataaacgcag ctaaaagtgc cattcaaagt gtttggaata gtatatcttc gtggatcagc
    19021 ggaatttgga acggtatcaa aaacactgct ttgaatcttt ggaatggaat tacaagcact
    19081 attagctcta aagtaaacga tggaaaaaat gcaatttcaa gcggttggtc caatctaaca
    19141 ggtattgttt ccgacatatt caataatgtt aaaagtacaa ttgctaacat ttgggaaggt
    19201 atcaaaaaga ctgttagcgc tccaattgat tggatcagag ataaaatcag tagtatcttt
    19261 gataatttga atatttctat accacatatt ccgttaccac attttaaatt gagcggagaa
    19321 ttcaatccat tgaaggggaa aatcccaacg ttgggtgttg attggtatgc gaaaggtagt
    19381 gtgtttaatt ctccgaatat tatcggtgtc ggcgaagcag gacctgaagc agttttacct
    19441 ttgaaaagat ctgtgctgca agaaattggt gatcgtatct tgagtagcac atcagtttca
    19501 tctagggcac aaacgattca acctgtgaat aactacgaat tcaatttcac aattgatggt
    19561 aacgcagatg aggttactat gaagcaaaca actcaacaaa tcattgatag cattacaaaa
    19621 gttcaaaatg ataatgcttc ggcatggcgt taaacaggag agtatttctc ctgttttttt
    19681 agtattaaaa aggatgtgaa aaaatgactg attgtataca ttctataatc gatggatttc
    19741 ctgattattt gcataaattg gctttagctg aaagaccaac cataccttct ccaaaaagac
    19801 agagagttga aacttctgtt ttaggaaggt taggtggctt agtacaagat tactcgtttg
    19861 aagacatgtc gtttacattg cactataact atttagagga tgtggaagac catcaagcgt
    19921 tcaagcaatc gttttatatc atgcgtcatt ggttaaatta tgcaaagaaa ttagaattct
    19981 ctgatgatcc caacgtctat tatgttatcc agactatcga tattggggat gcagaaaacg
    20041 atattgttga atggggagag ttcgatgtaa atattactgc gaaaccattc gcaagagttc
    20101 aagaagatgt acctataacc gtagataaac cacagtcatt taacttgctg aataatagtt
    20161 tagaagaaag ttttccaaag attatcatca ctccttcagc tacttcatgc cagttcatct
    20221 taaatgatta tgtgtttagt tttgaaggct tagtagtagg aactgacgta gtcattgata
    20281 gtgatttgat gctttgctac gaagagcaat cggacggaga tattttagat cggtccaaca
    20341 aaatgaagac catgcaatat ccgacattgc aagtggatat taattatttt aattgtactg
    20401 gtttgagcaa aatacaaatt tatcgtaatg ggttaaggta ggtgaaatag atgatcgata
    20461 atttaataac tatttacgat aaaaacgacg cgaataattt agctgaacat ttatatgata
    20521 cgcaaggttt aggcgctttg tcagactggt taacagctac tgttagcaat aaattaaacg
    20581 gagccgagat atttcagggt acttatccaa taagcggaac taatgcagat ttgattgtag
    20641 aaggacgtat tattcagtgt tatgtagatg aaaatcgagc aaaacagcgt ctacggattt
    20701 attatgcaaa gacttctgta ataggcaata cgatagaagt aaaagctgaa cctattttca
    20761 atgatataag aaaatcggtg ttgaataaat atgacagtgg aacagaaaag atcactgcta
    20821 gtcaggcatg gcaaaacgca aaaactttag cgaaaccagt tattccttca cagttttctt
    20881 tctcgtcatt agtagatacg cttgctaatg tgaagataga aaaggcgaat tttttagaat
    20941 tctttggtgg aaaagaggga tctattctag atcgatttca tggggaattt ctaaaagata
    21001 ataacacatt acgtcatgaa aaaaggctag gcacggatca taaaatcaaa gcgatttata
    21061 ctaaaaactt aactggtctt gacttagaga ttgatgctca aagtgtttta gttggagttt
    21121 atccattcat tagcagctct tcagaaggag aagacgagat cactctacca gaagaagtta
    21181 ttttcacgga ttacgtggat gattatcctg ctggatatgt ttcttttgtt gattttaaag
    21241 acaaagcgac tgatgtagcc acattaaggg aagctgctaa agactggttg aaaacaaaca
    21301 tagataaaca aaaaccacaa gtgagtggtt cgattgaatt agtaccattg aggcatcaaa
    21361 gaggctatga aaaatttgtt gatctagaaa aagtttcgat gggtgacgga gtagatgtgt
    21421 atcatccaca gttaaaagtg aatatgtcag cgagaattgt ggaatatacg tttaatgttc
    21481 taaccaattc atacgataaa ttagttgtag gaaacgtcaa aacaaacttc ttagaaaaca
    21541 cagagaataa tgtcagcaat ttgattaatg atgccattga tcaattgaaa aacggtggcg
    21601 aaatcagtga tttactcaat gatattgtag atcatcaaac tgatatgatt actggtcaaa
    21661 atggtggtta tgttttatta gatcctaaag aagcgcctag tcgtattttg attatggaca
    21721 caccagataa gaataccgca aggaatgttt tacaaatcaa caatgctggt attggttttt
    21781 ctaaaactgg cattaatgga acatatgaaa cggcatggac gttagatggc ggattcaatg
    21841 cctcgtttat tacggctggt gaaatagtag gaattactat tagaggtact acattaatta
    21901 gtgatggtgc tgattataga acaagtattg ctaatggcaa aatgacttgg tactcaaaaa
    21961 aagttaacaa agatattatg gagctagaag cacgtgatta tgtaagtgct gatgccggta
    22021 ttgtatcata caccatgaaa actggtggtg gtttcatgat tagaaatcca cagggtaact
    22081 tggtttttag tacgtgggat aatggtaata acagaccgtt tctatctttt ggtgcgccca
    22141 atttcaggta tagcaatgct agttatgtaa cttctggcga cggtagttct ttaagcatta
    22201 atggtagtgc gggtaactca tgggaattta aggtagctgg taggactatg aaatttacta
    22261 gtgatggtat gctaacgtta ccaggttgtt tttttggttc atgggaagat gggaaacttg
    22321 ctaggtttga acaatcaacg gtacaagtat ataaagattt tactgttaga ggtactaaaa
    22381 actcaactgt accaacagaa cattatggac aacgactatt gaacgcttat gaaactccag
    22441 aatattattt cgctgattat ggggaagccg ttacaggtga cgatggtaaa gttcgtgttg
    22501 atattgaccc catgtttgct gaaacagtaa atctaagtcg gtatatgaca catgtgacac
    22561 ctacagaact agttttgtgt gctgttactc atgaagatat tgaccatttc atcattgaaa
    22621 ctagtaagcc aaacgtatta gttagatgga atttagtggc acaccgtcta gggtatgaag
    22681 atattagatt aaaagaggat acagcatatg atagcacagt gcttgaccaa aaacgttttt
    22741 aaaacgaaga caaggaggta tataaatggc tagcagttta tataatttgg ctttagattt
    22801 cagcaaagaa ttaaactaca ccaaagctat tatggctcgt caaggtgata aagggattac
    22861 ggtgactgtt aaaccatttt taaatggctt gcagatggat acgagtggcg gaacatttac
    22921 tttaaaagga acaacaccat ctaaccgtta tgtagatagt gttgcaacta gcgtaactag
    22981 tgaagaagtc atattttctc ttgatggcac atttatgagt gaagcaggat attataaaca
    23041 ctgctacgta gaatatagaa aaggtaatca aattttaaca acgcaagaca tcattttttt
    23101 ctcactagga gtgtctgaca tttcgcaagg ccaagccgat gaatacgttt cgcaattgga
    23161 agagttgatt cgaaagtata acgaaacttt tgatgctttt atggctgaaa ttaaaggtag
    23221 agtggatagc ttaaatcaac agattactga tttaactggt caagctaaaa cgctacaaga
    23281 caagttagat gctctgaaag aagaaatttc taaattaggt aacttgcaag tcatgtacag
    23341 taacagcatc gacttcgggg gctatgatta ttc
//
LOCUS       DADQDV010000044        23249 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.044, whole genome shotgun sequence.
ACCESSION   DADQDV010000044 DADQDV010000000
VERSION     DADQDV010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 23249)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23249)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23249
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.044"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            29..886
                     /locus_tag="J8S10_001813"
     CDS             29..886
                     /locus_tag="J8S10_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HAZ9630397.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            1001..1921
                     /gene="pstC"
                     /locus_tag="J8S10_001814"
     CDS             1001..1921
                     /gene="pstC"
                     /locus_tag="J8S10_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HAZ9630398.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            1921..2805
                     /gene="pstA"
                     /locus_tag="J8S10_001815"
     CDS             1921..2805
                     /gene="pstA"
                     /locus_tag="J8S10_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HAZ9630399.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            2820..3626
                     /gene="pstB"
                     /locus_tag="J8S10_001816"
     CDS             2820..3626
                     /gene="pstB"
                     /locus_tag="J8S10_001816"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HAZ9630400.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            3642..4400
                     /locus_tag="J8S10_001817"
     CDS             3642..4400
                     /locus_tag="J8S10_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HAZ9630401.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGINLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            4413..5090
                     /gene="phoU"
                     /locus_tag="J8S10_001818"
     CDS             4413..5090
                     /gene="phoU"
                     /locus_tag="J8S10_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HAZ9630402.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            5328..5627
                     /locus_tag="J8S10_001819"
     CDS             5328..5627
                     /locus_tag="J8S10_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630403.1"
                     /translation="MQKKISIITIFFICVLTSWVIQHQAALYEVPVIEIEKVRIKEDH
                     QLITGRLMNTDQKGESIYLSVPYQKNQIETANIKARQMYLVQMHGDEWQLVAKKK"
     gene            5653..6360
                     /locus_tag="J8S10_001820"
     CDS             5653..6360
                     /locus_tag="J8S10_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HAZ9630404.1"
                     /translation="MSIGAMLLIGGKQGLFALGSLIINIVLLLLLLLIFTKTEGISLL
                     NISILFVVIGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYE
                     ELNYLTRPYRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQV
                     GRDVIGSMTNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVL
                     SIPISVLFFLTVRRLKR"
     gene            6357..7124
                     /locus_tag="J8S10_001821"
     CDS             6357..7124
                     /locus_tag="J8S10_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HAZ9630405.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            7224..8792
                     /gene="liaX"
                     /locus_tag="J8S10_001822"
     CDS             7224..8792
                     /gene="liaX"
                     /locus_tag="J8S10_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HAZ9630406.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEITQVQL
                     STTTGSIYLKDTDK"
     gene            9092..9409
                     /locus_tag="J8S10_001823"
     CDS             9092..9409
                     /locus_tag="J8S10_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HAZ9630407.1"
                     /translation="MKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVAF
                     GSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDEW
                     SDF"
     gene            9409..9759
                     /locus_tag="J8S10_001824"
     CDS             9409..9759
                     /locus_tag="J8S10_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HAZ9630408.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            9926..10864
                     /locus_tag="J8S10_001825"
     CDS             9926..10864
                     /locus_tag="J8S10_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HAZ9630409.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            10879..11709
                     /locus_tag="J8S10_001826"
     CDS             10879..11709
                     /locus_tag="J8S10_001826"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HAZ9630410.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            11753..12778
                     /locus_tag="J8S10_001827"
     CDS             11753..12778
                     /locus_tag="J8S10_001827"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HAZ9630411.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPAEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQIMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            12793..13731
                     /gene="galU"
                     /locus_tag="J8S10_001828"
     CDS             12793..13731
                     /gene="galU"
                     /locus_tag="J8S10_001828"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HAZ9630412.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKKLEAEGSKIDHNPKGITEIKEEKKK"
     gene            13856..14296
                     /locus_tag="J8S10_001829"
     CDS             13856..14296
                     /locus_tag="J8S10_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HAZ9630413.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            14299..14901
                     /locus_tag="J8S10_001830"
     CDS             14299..14901
                     /locus_tag="J8S10_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HAZ9630414.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIMIDVKDAAGKAGDTVNEG
                     MSEAKPVADDTKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
     gene            complement(14969..16075)
                     /locus_tag="J8S10_001831"
     CDS             complement(14969..16075)
                     /locus_tag="J8S10_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HAZ9630415.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVERFDAISDILTGTDSYTDLASIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            16285..17286
                     /gene="ccpA"
                     /locus_tag="J8S10_001832"
     CDS             16285..17286
                     /gene="ccpA"
                     /locus_tag="J8S10_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HAZ9630416.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            complement(17622..19967)
                     /locus_tag="J8S10_001833"
     CDS             complement(17622..19967)
                     /locus_tag="J8S10_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HAZ9630417.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
     gene            20246..21148
                     /locus_tag="J8S10_001834"
     CDS             20246..21148
                     /locus_tag="J8S10_001834"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HAZ9630418.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQIFDPEVFPELLAEEVIL"
     gene            21361..23136
                     /locus_tag="J8S10_001835"
     CDS             21361..23136
                     /locus_tag="J8S10_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HAZ9630419.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSFYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYSSSKKMLPWFLGLAVSFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEAKKLKERPFLLSKQEWLKLSLFLLPLVGFSIVYQWIEYKNETTYSIAAIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALDASPTFHAVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYQKGT
                     IKKKKEFYLMGSGDGKTMNDLPIVFAFLKSGYAYAWRYKDFHQGGNYSFGTQEQVEQA
                     QELLNLPLMDNWIDSSDPRTPDFQLTKTAKVANVMIKIYQVLAIPVLIASIAGILLMI
                     LGTAFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
BASE COUNT         7402 a         4136 c         4912 g         6799 t
ORIGIN      
        1 catactttag gattaaagga gatttctaat gaaaaaactt aaattattct taccaataat
       61 aggattagcc attcttttat caggctgttc aaagtggatt gatcgaggag aatccattac
      121 ggctgttggc tcttctgctt tacagccttt agtagaaaca gttgctgaaa cttaccagac
      181 agaaaatcct ggaaaattca tcaatgtaca agggggcgga agcggaactg gtttgtctca
      241 agtacagtca ggagcagtcg acatcggaaa ctctgatttg tttgcggaag aaaaatcggg
      301 gatcgatgcc tcagcattag tcgatcatcg agtagcagtt gttgggatca ctcctattgt
      361 gaacaaggat attggcgtaa aagacatcag tatggaaaac ctgaaaaaac tatttacagg
      421 cgagatcaaa aactggagtg aagtcggtgg aaaagatcag ccagtagtta tattgaaccg
      481 cgcttcagga agcggaaccc gtagcacgtt tgaaaaatgg gtattggacg gagaaacagc
      541 tgttcaggca caagaacaag attcaagcgg aatggtgcgc cagatcgttg ccgacacacc
      601 cggtgcaatc agctatgttg ctttttctta tgtttccgat gatgtagata cgttgaatgt
      661 taacggtgta gaaccgacag atgaaaatgt gacaacgaac aaatggacga tttgggcata
      721 tgagcatatg tacacaagag atcatccaaa aaaactgaca aaagaatttt tagactatat
      781 cttatctgat gaagtacaag ataacatcgt tggagaacta ggttatatcc ctgtttctca
      841 tatgaaagtc gaacgtgatt ggcaaggaaa tatcgttaaa gagtaatctt tacacaaaat
      901 ttacaaactt agctaaactt ttacatgtta ttaaaaccaa attgatgttc aatttgtaca
      961 ctgagtgagt atgttaaacc tgattaaggg ggagtcatct gtggaagatg tgaaaaaagt
     1021 attattaaca aaatcaaaac gttcaaaaat ggaacagcgt ggaaaattca tcagtttttt
     1081 atgtatcgcg ctgatcgtgt tggttgtatt atctattttt tattttgtag ctagtaaagg
     1141 attggccacc ttttttactg ataagatcaa tgtatttgat tttctgtttg gtacagattg
     1201 gaatccaagc caaatcggag caaatgggaa accaatggta ggggcattgc ctatgatcac
     1261 aggttcgttt attgtgacct ttttatctgc tatcgttgcc acgccatttg ccattggtgc
     1321 agcagtattc atgacggaga tctctcctaa aaacggaacg aagatcttac agccggtcat
     1381 cgagctgctt gtaggtattc cttctgtcgt ttatggtttt atcggtttat cagttatcgt
     1441 gccttttgtc agaagtattt ttggcgggac agggtttggt atcttagctg gtacatttgt
     1501 gttgttcgtt atgatcttgc cgactgtcac aacgatgact gttgatgcat taaaggcagt
     1561 gccacggcac tatcgggaag cttcattagc gcttggtgcc acaagatggc aaacaatcta
     1621 caaagtcgtg ctacgagcag ccgtgcccgg gattttaaca gcagtcgttt ttggtatggc
     1681 tcgtgcgttt ggtgaagcct tagctatcca aatggtcatc ggtaatgcag cattgatgcc
     1741 aacaggactt actactcctg cttctacatt gacgtccatc ttaacaatgg gaatcggaaa
     1801 tacaatcatg ggaacagttg aaaataatgt gttatggtca ttagcgctga tcttgctatt
     1861 gatgtcatta ttctttaata tcgtgatccg tatgattggg aagaaaggag agctgaaata
     1921 atgaacgcaa aacgctcaga taaaattgct acaggtgttt tatatatagt ttcggggatc
     1981 atcgtattga ttttagcagc tttactactt tatatcttag ttcggggaat accgcatatt
     2041 tcatggtcct tcttgaccga accttccaaa gcctaccaag aaggcggtgg aatcgggatc
     2101 cagctattta actcgattta tttgcttttg atcacgatga tcatcagttt tcctatttct
     2161 ttaggtgcgg gtatctatct ttcagaatat gctggaaaaa actggctaac agatgtgatt
     2221 cgcacgtcga ttgaaatctt gagctcgttg ccttctgtcg ttgtcggttt attcggtttc
     2281 ttggttttcg ttattcaatt ccagtatggt ttctcgatta tttctggtgc attggctttg
     2341 actgtattca acttgcctct tttgactaga acagttgagg agtctttaca agcggtccat
     2401 tacacacaac gagaagcagg attggcctta ggtttgtcac gctgggaaac agtgataaaa
     2461 gtggtggttc cagaagcgac accagggatt ttgactggtg tgatcctaag ttctggaaga
     2521 atttttggtg aagcagctgc attgatctat acggctggac aaagtgcacc tgcgttagat
     2581 tttacgaact ggaatccatt aagtgtttca agcccgatca gcattttccg tcaagctgaa
     2641 acattagctg tccatatttg gaagatcaat acagaaggca cgatgcctga tggtgtttct
     2701 gtttcggctg gcgcttctgc cgtgttgatc attgctgttt tactgttcaa cttcggcgct
     2761 cgtgcgattg gcaaacgatt ataccgaaaa atgacttcag cctaaggaga agaagcaaaa
     2821 tgaaaaaata taactggaat gaaacaaatg tcatcaccat gccaaaagag aaagaagtag
     2881 cactatatac ggatgatcta catgtctggt atggcgacaa tgaagcaatc aaaggagtgg
     2941 atctggaatt tgaaaaaaat aagatcactg cactgattgg tccttccggc tgcggaaaat
     3001 ctacgtatct tcgttcgttg aatcgaatga atgatgggat cgctaatacg aaaatcactg
     3061 ggaaaatcat gtatcaaggc gtagatatta atgcgcctca agtggatgtt tatgagatgc
     3121 gcaaacggat tggcatggtt tttcaacgtc ctaatccgtt cagcaagtcg atttatgaca
     3181 atattacatt tgctttgaaa cagcacggcg aaaaaaacaa aaagaaatta gatgaaatcg
     3241 ttgaaacaag cttgaaacaa gctgccttgt gggaccaagt aaaagacagc ttggacaaaa
     3301 gtgccttggc tttatctggc gggcaacagc aacgtttatg tattgctcgt gcgatcgcga
     3361 tgaaacctga tatcttgctg ctagacgagc cggcaagtgc tttggaccct atttcgacag
     3421 gaacggttga agaaacactt gtaaacttga aagaagacta tacgatcatc atcgtgacgc
     3481 ataacatgca acaagcagct cgtatcagcg actatactgc ctttttctat ctaggaaaag
     3541 taatggaata tgacaaaact aacaagatat ttaccagacc aaaaattcag gcaaccgaag
     3601 attatgtgtc cggtcatttt ggttaagacg gaggcctcaa catgacaaaa gaaattattt
     3661 catctaaaga tcttcatctg tattatggaa agaaagaagc actaaaaggg atcaatctaa
     3721 gtttcaatca aggggaaatc actgcgatga tcggtccttc tggttgcggg aaatccactt
     3781 atctgcgttc tttgaaccgg atgaatgacc tgattccgaa tgtaacgatc accggaagtg
     3841 ttttatataa agacaaagac atctatggtc caaaaacaga tgttgttgaa ctaagaaaag
     3901 aaatcggcat ggtattccag cagccaaacc catttccttt ttctatctat gaaaatgtca
     3961 tctatggatt gaaattaaaa ggggaaaaag ataaaaaagt ccttgatcaa gtagttgaag
     4021 aaagcctgaa ggcagcgtct gtttgggatg atgtgaaaga caaattgcat aaaagtgctt
     4081 tatctttatc cggtgggcag cagcagcgtg tatgtatcgc acgtgttttg gcagttaatc
     4141 cggaaatcat cttattggat gaaccaacaa gtgcgcttga tcctgtttct actgggaaaa
     4201 tcgaaagtat gctgttagaa ttaagagagc ggtatacgat gatcatcgtg acccataata
     4261 tgtctcaagc ttcacgtatt tcagataaga cggcattctt tttagatggt cacttgatcg
     4321 aatacaacga tacgaagaag atattcatga atccagaaaa acaagagaca gaagattata
     4381 tttcaggtcg atttggataa ggaggaaacg gaatgctacg tacacaattt gaagaagaat
     4441 tgctgaatct ccataatcag ttctacgaaa tggggatgat ggtgagcagc gccgtgcaca
     4501 agtcagttcg tgcatacatc aaacacgata aaatcttagc ccaagaagtt atcgaaaacg
     4561 atataaatat caataacatg gaaacacgct tggagaagaa aagttttgaa atgatcgcat
     4621 tgcaacagcc agttacaact gatttgcgta tgatcattac ggtcatgaaa gctagctcgg
     4681 atttagaacg tatggccgat catgcggtgt ctgttgctaa atccacgatt cgcgtaaaag
     4741 ggcagacgag aataccggaa atcgaaaaag agatctccga tatgtccgat tatgtgaaaa
     4801 aaatggtgga caacgtccta gttgcttatg tcaaaacaga cgaaaaagac gcacgtacga
     4861 tcgccaatat ggatcaaaga gtcaatgact atttcaatcg aatctataat gcaacaatca
     4921 aaaatatgca ggaaaatcct gagacagtca tcagtggaac agactacttg aatgttgcca
     4981 gttatctaga acggatcgga gactatgtga caaacatctg tgaatggatc gtctacttgg
     5041 ctacagggaa aatcactgag ttaaatacga accacaatga gattttctaa actgaagctg
     5101 tgattatgcc gtttgtttag gaaaagaggt tgtgaaatca gcggttgtga aaaagctgtt
     5161 ctgcatcaag taataagaac agtcaaacaa aaaatagctc ctcatatttt tcgtttggct
     5221 ggacttatta ccgcagatgc aagcttttga acaccgttta ttcgggaaag ggtttgtgac
     5281 aaaacatgtc acaaaccctt ttcatcattt catagaaagg ataaagaatg caaaaaaaaa
     5341 ttagcatcat cactatattt tttatttgtg tgcttacttc atgggttatt cagcatcaag
     5401 ctgctttata tgaagtacct gtcatcgaga tcgaaaaagt acgaataaaa gaggatcatc
     5461 aattgattac aggaagactg atgaacacgg atcaaaaagg agaatcgatt tatttatcgg
     5521 ttccttatca aaaaaatcaa atagaaacag caaatataaa agcgagacaa atgtatctag
     5581 tccaaatgca tggagatgaa tggcagctag tagcaaaaaa aaaatgatgg ctggcttttc
     5641 ttcttcacaa gtatctccat tggcgccatg ttgcttattg gcggaaaaca gggtctattt
     5701 gctttaggaa gtctcatcat caatatcgtt ttacttttac ttttgttgct catctttact
     5761 aaaacagaag ggatttctct attaaatata tctatcctgt tcgtcgttat agggatgatt
     5821 attagcatat tggctttaga tggatggaat agaagcagta taatcaaaat ttcagctgca
     5881 gttacgagtg tttttttagc attttttatt tgtcttttga caatgaatca ttggaaagac
     5941 caaggactgc gctatgagga actgaattat ctgacacgac cgtatcgttc tgtttttctt
     6001 tctagcgtac tgattggaac agctggagga acactcgata ccgttatcac agtcattgcg
     6061 acattagaag aattgactaa gcgacaacca gaaataacag cgaaacagtt atggctttca
     6121 ggaaggcaag tgggtcgaga tgtgattggc tcgatgacca atatcctttt gttcgtctat
     6181 atcagtgggt cagttccatc gcttctttta tatttaggaa atcaatggtc gttcaaagaa
     6241 acgatagaac agcatttatc attggaattt ttacgcgtca ttgctggcag cttaggaata
     6301 gtattatcga tccctatctc ggtcctcttt tttctgactg taaggaggct gaaacgatga
     6361 atgtacttat tatacttgtt gggattttag caatcagcgt gctacttatt ggcggtacgc
     6421 aaggtatgta tattctttta ggcttattca tcaatttagg gatctttttc ctgttgttat
     6481 tcggttatca tcagaagtgg ccgatactgg cattgtcggt cataggattt ttattgattg
     6541 ctgtggttat cttatttttt atcaacggtt ataatctaaa aatgcgtgca gcttttgtga
     6601 gtatactgat ctttttattt tgtttcctac tattgcttcc tatcactgat tttttagcga
     6661 tccaaggttt tacatcggta gaactagaag aattatctgg cttagataag actttagcga
     6721 ttgattttag attacttacg agatcgttgc ttctgattag tcttagtggt gctgttttag
     6781 atgctagtgt agcaatttct agtgggacat tcgaagtata tcaggcaaat ccgcaattat
     6841 ctttttacca attgcgccat tctagtttcg ctattgctaa aaaaatattg gcgtcaacag
     6901 taatgacact tctttttgca ttcatgggaa gttctttagc gttgatcctc tggtttattg
     6961 atttagacat tccttttcag caagtgatca atgaaaaatc atttgttcta gaatatacga
     7021 tggctattct taccacattg tctgcactac ttgttcttcc tttaacctgc gtgactacag
     7081 catatctctt tacaaaaaag aaagaacaac tcaagatgga gtaaaagtta caacttaagt
     7141 cctatgacat ttttactgaa tcagtgcata atatggatgt aaggaaaagc ttgcaaacaa
     7201 ttttgcttaa ggaggcaatt tccatgaaag aaagagaacg tattttagat ttagtgaaaa
     7261 aaggaatcct ttcgactgaa gaaggcttag atttattaga aagcatggca actgaaaaag
     7321 acgaaaagca aataaaaaaa gaagcagaca aggtaactgc tagtcataaa gaaaaagatc
     7381 aggcaagtca attgatcgat aaacttgaaa acggcgaaga agaaatttct gagccagttg
     7441 atccaaagga aagagaaagg caagatcaag aaaacttaga aaagatctta gatgaactag
     7501 caactgaagc gaataaaact tcggcgcgtc tagatgaagt aaatgctcaa ttcgctgaca
     7561 ataaggcagc acgcaatgag aaacaggaag cattgatgca gctgaataca aaagaagaat
     7621 taggcgagtt gacagaagaa gaattagcac agcgtcagac gttagaagca gaaatcaaag
     7681 aattagaagc tagtggcgat acactgttag aagaacaatt gaaattagaa gcagaattaa
     7741 aagatatccg taagaatcaa tggtctgaga aaaaagaaac gtttactgat aagtttgaat
     7801 tgccagatga ttggaaagat caagcaacag atacactgaa tcaagtaggc gaaaaaatgt
     7861 cagaagctgg atcacagtta ggcaaattct tgaagaaaac attccaaact gtttcagaaa
     7921 cagtgaatga caacatggaa tggaaagatg tcagcttacg tgtccctggg attgcgacaa
     7981 cgaaatttga gcatgaattt tactatgaag ctcctgcagc aagtatcctt gatatcaagg
     8041 cagcaaacgg aaacgtgacg ttaaaaacgt gggacagcaa cgatgtgaaa gttgaagcta
     8101 agatcaaact ttacggaaaa atgggtgctg aaccatttga agcattctct gaacggagcc
     8161 agattgaggt taatgaagat catatctcct tccaaattcc aaataaacgt gtgcgtgcag
     8221 accttgtttt ctacttacct aaacgagtat acgaccacgc agctattaaa cttctaaatg
     8281 gcaacatcat gattgaaaca ttggaagcta aagatattta tacaaaatct acgaatggta
     8341 acatcatcgt ggaccaatta actgcaacga tgctggaagt agaaggtgta aacggcaata
     8401 tcgatattcg aaacgggaac atcttagatt ctattatcga aacagtaaat ggtacagtga
     8461 catttggtgc gacagcagaa aacctttctg tgtctttggt aaatggtgat gtacgtctta
     8521 cgattaaaga agataatttg aaaaaagtag aagcaagttc agtgaacgga aatgtcaaag
     8581 tcgctttacc agatggcatc ggtttggaag gacatgctaa aacaagtctt ggaagtatca
     8641 acagccgtct gtccaattac gaagtagttc gtgagaaaaa agaacggaca aaccaaatgt
     8701 tgcaattccg tcgtgtttca gatggtgaaa tcacgcaagt gcaactttca acgacaacag
     8761 gaagtatcta tttaaaagat acagataaat aaagaggttg tgaaagagat gttcagcctt
     8821 gagcaataag aagcgatttt gtaaaatagc ttcccctatt ttacaaaatt gtgccttatt
     8881 gccgataggc tatctcttga acaccgttta ccaagagatt atgaacctgc caattatcgc
     8941 cgagtcacaa ggaataattt cagaaaaagc tcgtcacgtt ttatgaatat ggtaatttgt
     9001 gaccgagaat tttgcagaaa gacaccgatt aagaagaagg ttgtcacaac gattttcttc
     9061 atttaaaata gtagaacaga ggtgagacat gatgaaaaaa aagttgacaa aatccaataa
     9121 aaatgttgtt ttgacaggga ctttagcagg aataggagaa tacatcggga ttgatccgac
     9181 tgttatccgt gtgctttatg tattcctgag cttagttgct tttggaagtc caatcatttt
     9241 atacatttta ttagctttga ttatcccatc tgcgcgttct gcacgaacaa actatggaca
     9301 taacaatgca tattatgaaa aaaacaatta tcgtgaacaa actcgtgaac aaacaaaaaa
     9361 acgcaaagaa gcggaaaaaa tcgatgatga cgaatggagt gacttttaat gtcgtacttt
     9421 caacgtattt tagttaatac gttaacattc atatcattgg ctgttctttt tcctgcgatg
     9481 gtccatgtga gcagtatttg gacggccgtt cttgccagct tcgtattgtc tgtgttgaat
     9541 atgtttgtca aaccgatttt gacgatactg tccctgccct ttacattagt cacattggga
     9601 ttgtttacgt ttgttatcaa tgcagcgatt cttaaaatga cctccttttt tgtgggagca
     9661 gaacatttta gtttttcttc attcggtgca gcgttgttag tagctatctt gatgtcgctt
     9721 gtcaatgtaa ttgtcagtga acataacagt agaaaataaa agaaagctgt gccgaactat
     9781 cggcgcagtt tttttattta gaatcaggaa tgcgttttct attacattgg taattaaata
     9841 aaaacgtttt ttttaattgg tagtactttt ggctagacaa tgataaaatg atagagaaca
     9901 ctctaataga aatgaggtag catgaatgtc agaagttgta aaagttagcc aattagtgaa
     9961 aaaattatct ttggaaatcg tgacaggcga cgagaaaagc ttagaccgtg tcatcgtaac
    10021 tggggacatc tcacgcccag gactagagtt gactggttat tttaattatt attcccataa
    10081 tcgtttacag ctatttggca gtaaagaaat cagttttgcg gaacggatga tcccagaaga
    10141 gcgtttgatc atcatgagaa gattatgtag tgaagatatg cccgcattta ttatttcaag
    10201 aggattaccg gctccagaag aaatgatcca ggcagcaaat gaaaatggga tagctgtact
    10261 gcgttctccc atctcaactt ctcgtttatt aggagaatta tccagttatt tagatggtcg
    10321 ccttgcccct cgaacaagtg tccacggtgt tttagtggat gtttacggat taggtgtact
    10381 gattcaaggt gacagtggga taggaaaaag tgaaacagcg ttggagttga tcaaacgcgg
    10441 tcatcgattg atcgcagacg atcgagtaga tgtttatcag caagatgaat taacggtgat
    10501 cggagaaccg cctaaaatcc tggaacatct aattgaaatc cgaggaatcg ggatcattga
    10561 tgtaatgaat ctttttggtg cgagtgcggt acgtggctct atgcaagtcc agttggctgt
    10621 ttatctggaa gcatgggcaa aagataagaa atacgaccgt ctgggctctg aagacacgac
    10681 cgttgaaatc gcggaagtgg gcattccaca aataaaaatc cctgtcaaaa caggacgaaa
    10741 cgttgcaatc atcattgaag tagccgcgat gaatttccgt gcacgtacaa tgggctttga
    10801 cgcaacgaaa acatttgaag aaagattaag tcgcttgatt gaagaaaact caggcaacga
    10861 ctagcaagga gtgacaatat gttagcacaa atcaatcgag ttgcttttga gcttgtaggg
    10921 attcctatct actggtatgc attgatcatc gtatcaggta tcattatcgc catgtggctt
    10981 agcagcagag aggctgttcg ggtaggatta aaagcagatg atgtgacaga ttttatgttg
    11041 tggggattgc ctatctccat tattggtgct cgcttatatt atgttttatt tgatcttccc
    11101 cagtatatag ctgatccaat ccaaatattc aatatccgtt caggaggctt agctatttat
    11161 ggcggactga ttgcaggcgc gatcacgctg tattttttta ctaaatatca ttttatttct
    11221 ttgtggactt ttttagatat cgctgcacca agtgtattat tagcacaggc aatcggtcgt
    11281 tggggaaatt tcatgaacca cgaagcatat ggaccagaca cgacgcgaag cttcttagaa
    11341 agtctgcatt taccgcaatt catcattgat aatatgtata tcgaagggat ctatcgtcaa
    11401 ccaacatttc tttatgaatc actttggagt ttgattggat ttattttgct tttgttttta
    11461 cgaaagaaac cacacctttt gaaaaaaggc gaagtccttt tatgttatct aatgtggtat
    11521 agtttcgggc gtttctttat tgaaggatta cgtacagaca gtctttactt tttaggtgtg
    11581 atccgtattt ctcaattatt atctgctgtg ttatttgtcg gtacattgat tctatttatt
    11641 tggcgcagaa aaaaaggaaa tttaccggat tatgaccgct cattaggaaa aaatcaacaa
    11701 attatctgat ttttagagcg ttaaaaatga aaaaaatttc aggagtggta aaatgaatta
    11761 tagagtagcg gttttaggac caggctcttg gggtactgct ttggcacaag tcctcgccga
    11821 aaacggacat gacgttcgga tttggggaca tcgtgcttca caagtagaag aaatcaacac
    11881 ccaacacacg aatcaacgtt atttaccaga tcattatcta cccgattcca tccaagcatt
    11941 caccaatatg gaagatgcag taaaagacgc agatgcggtg ctattcgtca ttccaacgaa
    12001 agcaatacgt tctgttgcaa aagaactagt gcctaaattg aatacaaagc cagtgatcat
    12061 ccatgcaagt aaaggattag aacagggaac acataaaagg atctctgaca tcttgttaga
    12121 ggaaatccca gcagaaaaaa gaaaagctgt tgttgttctt tctggaccaa gccatgcaga
    12181 agaagtagcg aaacatgaca tcactacgat cacagctgca agtacagatg caaaagcagc
    12241 aaaatatgta caagagctgt tcatgaataa ttattttcgg atctatacca atcctgatgt
    12301 gatcggtgta gagatggggg cagctttgaa aaatattatt gctattggtg ctggcgctat
    12361 tcacggctta gggtttggcg ataatgcaaa ggcagcaatc atgacgcgcg gattagctga
    12421 gatcagccgt ttaggtgtag caatgggtgc caacccgctg acctttatcg gattaagcgg
    12481 agtaggcgat ctagtcgtta cttgcacaag tgttcattct aggaactggc gcgcaggcaa
    12541 cttgttagga caagggcagc ccctagaaga ggtgctagcc aatatgggaa tggtcgttga
    12601 aggtgtgaat actactcaag cagcgatgga actagcccaa ataatggaaa tcgaaatgcc
    12661 catcactcaa acaatctatg aagtgctgta tgaacaaaaa gaaatcaaaa cagccgcaaa
    12721 agaaatcatg ttacgtgatg ggaaaaaaga aaatgaattc tcattaacaa ttttttgaag
    12781 gagcgaatgt atatgaaagt caaaaaagca gttattccag cggcaggatt aggaacaaga
    12841 tttttaccag caacaaaagc tatggcaaag gaaatgttgc caattgttga taaaccaaca
    12901 atccagttca tcgttgaaga agcgttgaaa tcaggaatcg aagacatctt gatcgttaca
    12961 ggaaaagcta aacgaccaat cgaagatcac tttgattcaa atattgaatt agaaacaaac
    13021 ctaagtgaaa aaggaaagac cgaattattg aaattagtag aagaaacgac agatgtcaac
    13081 ttgcatttca tccgtcaatc tcatccaaag ggtttaggac atgccgttct tcaagcaaga
    13141 gcctttattg gaaatgaacc gtttgtcgtt atgctaggcg atgatatcat ggaagatgaa
    13201 gtaccattga cacagcaatt aatcgatgat tacgaacgta ctcatgcttc tacgatcgcc
    13261 gttatgcaag ttcctcatga tgaaacttca aaatacggaa ttatcaatcc aggagaagta
    13321 ttggaagatg ggttatacaa tgtcaaaaac tttgttgaaa aaccagatcc aagcaaagca
    13381 ccaagtgatt tagctattat tggacgttac ttattgactc cagaaatttt tgatgtattg
    13441 tccgagcaac aaccaggagc cggaaatgaa atccaactaa ctgacgcaat cgatacattg
    13501 aataaaacac aacgcgtatt tgcccgtaaa ttcacaggta aacgttacga tgtcggtgac
    13561 aaatttggtt ttatgaaaac aagtattgaa tatggtctaa cacatccaga agtaggtgca
    13621 cctttacgtg agtatatcct gtctttaggt aaaaaattag aagcagaagg aagcaagatc
    13681 gatcataatc caaaaggaat aacagaaatc aaagaagaaa agaaaaaata accctttttt
    13741 ctaacgagct tcagctgcta attgaataaa aagtagttga agctcgtttt tatttgttta
    13801 aaaaacacga aaatgctatc cttatagaaa agagagacaa gaagggagtt tgatcatgtc
    13861 aggaggagaa attgcaggat tgatcgcagc aatcgccttt gcgatacttg tcgtttttat
    13921 cgttcgtgtg ttgttgcaag tttctaaaac tttagaaaaa gtagatcaga ctgtagcaga
    13981 agcaaatacg acgatcgaaa tcgtcacaaa agacgtagat cttttgtcta gacaagtaga
    14041 aggcttgctg gtcaaaagta atgaactgct cttggatatc aatggaaaag tcgcaacgat
    14101 cgatccattg ttcacagcag ttgctgattt aagtgaaagt gtatcagaac ttaatcattc
    14161 tagtaaaaac atcgcgacga aagtcggcgg aatcggtaaa acgacagcta aagcgacggt
    14221 tgccggaaaa gtcggtggga cagcgatgaa attttttaaa aacaaaaaac atactgaaac
    14281 gacaggagga aaataaaaat ggctaaaaaa ggtggatttt tattaggtgc agtagtcgga
    14341 ggaacagccg cagcaatcgc cgcgttattg ttagcaccaa aatctggtaa agaacttcgg
    14401 gatgaattag ctgcccaagc ggatgatttg atggatatgg cttcagatta cacagatatg
    14461 gcgaaagaaa aatcgactga gttaacaggt attgcaaaag aaaaagcgca agatctttct
    14521 caacaagcag gtgatctagc aggtagtgtc aaacaaaaag taagtgaatc agcagatgaa
    14581 gcaggaagtg aatctgacga tatcttgtta aatcttaaag aacaatcagc tgacttatct
    14641 aatcgtttca aaaaaacggc agaagatatg aaaaaacctg cagatgaatt aggaagtatt
    14701 gctaaagata cttcagaaga tatcatgatt gatgtaaaag acgctgctgg taaagcagga
    14761 gatactgtca atgaaggaat gtcagaagca aaaccagttg cagatgacac aaaagaaatg
    14821 atgaaaatgg caaaagaaga tgcgaaagaa gctaaaaaag aaataaaaga tacaatgaca
    14881 gattcatcta caaatcacta aaatcactaa aatcacaaat ttatagaata aaaaggtggg
    14941 agcggactag ctctcacctt ttttactctt atttttctaa aactagtaat tcttttggtg
    15001 tagtcgtgaa tggcacacag ccatcgcttg tcacatatac acagtcttcg atacgtaccc
    15061 ctactttttc aggaatatag attcctggtt caagagagaa gcacatccct tcttcgatta
    15121 ctaagtcatt tccttctaca agggaaggga attcgtggac ggttgttccg atcccgtgac
    15181 ctaaacggtg attgaaatat tcgccgtagc catagctgtt gatcacgttt cgtgcgattt
    15241 gatcaagttc acctgctgtc acacctggac ggacggcttc ttgtgcggca agctgtgctt
    15301 caagagtgat gttgtatatt ttttcttgga agtcggttgg tttttgataa gcaattgtac
    15361 gagtagcatc actgcaatag ccattccaaa caacgccaag atcgaataac acaagttcat
    15421 tcggtgaaat cttcgtgttt cctggtgtac catgagggct tgcagcattt gctcctgcaa
    15481 ggactaatgt gtcgaaagac atttgtgaaa caccttgttt tttcaattgg tattcgattt
    15541 ctgcaatgat cgcttgttca gtcacgcctt ctttcactgc tttaaagcca atctcaaatg
    15601 caacatcggc ccatttacca gcttcgatca gtttgtcttt ttcctctaga gttttgatca
    15661 gttgtagacg ttggatgatg gaagctagat cagtgtaaga atccgttccc gtcaagatat
    15721 cagagatagc atcgaagcgc tcgacagtca aggcgttctt ttcaatccct acattgccag
    15781 gctgaccata gcgagcacga agttcttttc cgatgatctc ccaagggttt tcgctgtcta
    15841 aatagccacg gacatcatac gcccaactac tgttttgagc atcttcaact tccaaagcag
    15901 gagtgaaaag gaaaggatct tgttcaagag ggataaaaag agctagtaca cgctcatgag
    15961 gatcactttc gtatccggaa aagtaagcga tgtggccagg gtcgctgata taagccaatt
    16021 cgacttggtg ttgtgccatc cattgacgta gttcattgat ttttacgtta ttcatttggc
    16081 aacctacttt ctaaattaat tttgtattca ataattgtac cactgattta ttaaaagacc
    16141 aacgttctaa aaactgaaaa aagtaaaaat tttcatgaaa acagagataa aacggttgca
    16201 attcttgaga ttatttgata ttctatttta gaaatgtaag acgtattttc agaaaacata
    16261 taaaatatga ataggagaac acaaatggaa aagcaaacaa tcactatcta tgatgtagcg
    16321 agagaggcaa atgtttcgat ggctactgtt tcacgtgtcg taaatggcaa tccaaacgtc
    16381 aaaccagcaa caagaaaaaa agtcttggaa gttatcgatc gcttggatta tcgtccaaac
    16441 gcagttgcgc gtggcttggc aagtaagaaa acaacaacag ttggggtaat catccctgat
    16501 gtcagcaata tgttctttgc ttctttagca cgtggtatcg atgatgtggc aacaatgtac
    16561 aaatacaata ttatcttagc aaattcagat ggtaacgacc aaaaagaagt caatgtattg
    16621 aataacttac tggctaagca agtggacggc gtgatcttca tgggtcacca tatcacagac
    16681 gaaatccgtg gagaattttc acgttcaaaa actcctgttg tattagctgg ctctattgat
    16741 ccagatgaac aagtaggtag cgtaaacatt gattatgtat cagcaacaaa agatgcagta
    16801 aacaaattgg caaaaagcgg caataaaaaa atcgcttttg tcagtggtgc gttgatcgat
    16861 cctatcaatg gacaaaatcg tctgaaaggc tataaagaag cattaagcga aaataaccta
    16921 ccatatagcg aaggattgat ctttgaagca caatacaact tcaaagatgg tctatctcta
    16981 gtcgatcgga tccataatag cggtgcaaca gctgtctatg tttcagatga tgaattagcc
    17041 atcggtattt tggatggttt attagaccgt ggcgtgaaag taccggaaga attcgaaatc
    17101 atcacaagta acaattcact actgacagaa gtagctcgtc ctcgtttaac aagtatcaca
    17161 caaccattat acgatttagg ggcggtatct atgcgcctat tgacgaaaat gatgaataaa
    17221 gaagaagtcg aagaaaaaac gattatcttg ccttatggaa tcgaagaaaa aggatctaca
    17281 aaataataaa aggacaacca ttcagaggtt gtgagcctgc cgtttaactc tgcgttacaa
    17341 ggagcaattt caaaaaacag catttcatgt ttgatgaata ttgtgactcg tgattcggag
    17401 ttggcaggag aacaccgttt attcgggaaa aggggttatg acaaaatttt gtttaatcct
    17461 ttttttttgt cttaaaaaag agagaaagtg gttgaaatta catttatcgt atataaaaca
    17521 atccgtgtat agatgctgca ttatgttcac caccatcaaa aaaataaggg actgtgacaa
    17581 tactattgtc acagtccctt attactgtgt attctattaa atcaatcatc tttctcatct
    17641 gattctttgg ttgcttgatt cgctcttgca taagctgaag cggtgttcca gtaatctgta
    17701 tagttttcat cggtaccgcc aacgccaaat ttaaaggcgc ttttcttcgg tccatttttc
    17761 gcccatagcg attcaactgt ttttcctggt gtttggatgg attttttatt gacagtaact
    17821 tttccaggtg tttgaccagt aaatccagat acttttttct tcatcacatc agatgataat
    17881 tcgaatttct catcagtgcc aaaaatgtca ggttttgctt ggtaagcttg attgatcaga
    17941 ttggcaagat aattagccga acgtatcctt gctttgctgt ccattccagt attgtcatcg
    18001 tgccctgccc agctactgat ggtaatagac ggagtagaga caattagcca tgaatctcgg
    18061 tattcattgg tagaaccagt ttttccgacc caatctgctt ttcctagatt tccgtttaag
    18121 cttgagatgg catctttgaa tggtgtagtg atttttgcat tgatcacact gcgcatcatg
    18181 tcattcatga tcgatgccgt tgcttccgaa tagatccgga cagagttgct ttcgtgttta
    18241 taaattacat ttcctgcgtt atctgtgatg gaatcgatga tatagccttc ttcatagacg
    18301 ccgccgtttg ctaaagcctg aaatccattg gtctgttgaa gcgtcgtgac atctactgta
    18361 cctaaaggag cagattcaac gccccaattg tcatttgccg ggtagttcat ctttgccaag
    18421 tagtgctcgt aagcatattg tttcgatcca ccggaattca acacatcttg atataagtga
    18481 taagccggga tattgttgga ccattctagt gactcacgga cggtttggaa ggtgttcgat
    18541 ccttcgttag tagcattgac gattttctcg ccagcatttt ctccttcttg ccaagttgtt
    18601 gcataatctg atacacggga ttctgatccg ataagcccca tgtcgattgc aggtccataa
    18661 acaagaactg gtttgattga tgagccagct tgacgttctg tatcgaaggc atggttattt
    18721 tgattctgac tgtaattccg tccgccaacg aatccgtaga tgcggccagt tctgttatcc
    18781 atcaatacat ttccggtttc tacttgactg ccagcaccat catctaacat gtatccataa
    18841 ttttctacgc cattttgcaa tgcagcatag acatctttat cgattgtcga atggattgta
    18901 tatcctttat tttggatcgt ttgctgtgcc ttttgataat aagcgtcact gaccgatgaa
    18961 tcagacatat cagcgttgtc tttttcagcc aattgttgtg caatgattct tgttgcttca
    19021 ttcatcacag tataatacaa gaattctctg tcagtctgtt ctgcgatttg ttgtggtaga
    19081 aagtcttttg taaggtcata ggcttttgct tcttcgtatt gttctttcgt aatttggcct
    19141 tcacgataca tactgaataa aacaaaatct tttctggcaa ggccggcaga aagatcttct
    19201 tttagcgcac ctgtgttcgt gtatggacta tacgtgatcg ggctttgggg taatccagcg
    19261 atataagcag cttgcggcag cgtcacatct tttgcatcta caccaaagat tcctcttgca
    19321 gcttcctgga ctccagcaat gttttgtccc ttattattac gaccaaatgg tgagacattc
    19381 aaatacgtag caatgatctc atcttttgaa aagtattttt ctacttgtgc agaaagaatg
    19441 atctcgtttg ctttacgttt gaatgttgtt tcatctgtaa ggatctgctg tttgactaat
    19501 tgctgtgtca aagttgatcc accagaagag ccaataccag tagcttcaga tactaatgct
    19561 cgtaaaacag ctttaggaac gtaaccttgg tgtttatcga agtattcatc ctctgtgctg
    19621 ataattgcag ttttcaataa aggtgaaatt ttatcagatg aaatagtcgt gcgcatcaga
    19681 tctgtctgga tttttgatat ctctgtatta tctgcataaa caatctttga cgtttctgta
    19741 atgtttccta gttctgtctg cagtgctttt ttagtcggca attgtgtgtc ttcgacgaga
    19801 taggcaaaat agccagcgcc tattccaata cctagagctg cgaacatcaa aagaagaaca
    19861 gtaataaaaa cagtcaatga ttgaaaaact ctaaaaataa tcttaggaac aaaccatttt
    19921 tctttttttc ttctattctg tttttttcga gtatttttgc gtggcaaaag ggtcacctca
    19981 actaatggtt ttatttcgct aattatagca aataatagaa caaaaaaaca gacaaggctg
    20041 tttttggcag gaatttcttt tttaaaagag ttaaaacgtg agaaaatgat cttttttata
    20101 aaagagttct taagcttttc tttagagaaa atttcagtta ctatggagaa cagggcaaag
    20161 aaaaatcaat cattttcttt gtatatcatc ttaccaatat ataggaattg ttagtaacaa
    20221 ttgcctttca aggaggaatc catccatgtt attaggctca cacgtcagca tgagcggaaa
    20281 gaaaatgctg ttaggagcag cagaagaagc agccagttat ggatcttcga cttttatgat
    20341 ctatacaggc gcccctcaaa acactagaag aaaagccatc gaagagatga atattgatgc
    20401 cggaaaagcg tacatggcag aaaacggtct aacaaatatc gtcgttcatg ccccttatat
    20461 cattaatttg gggaatacga tcaaaccaga aatgtttcct tttgccgtcc aatttctgag
    20521 agaagagatt gttcgtgcgg aagctttagg cgctactcaa attacacttc acccaggtgc
    20581 tcatgtaggg gcaggaacag aagccggaat tgctagaatt attgaaggct tgaatgaagt
    20641 tttgacaaaa gaacagacgg cacaaatcgc tttggagaca atggcaggta aaggtacgga
    20701 aatcggtcga acatttgagg aattagcgca aatcatcgat ggagtaaaat tgaatgaaaa
    20761 attatccgtt acttttgaca cctgtcatac gaatgatgcc ggttataata ttaaagaaga
    20821 cttttcaggt gtaatggaag agtttgataa gatcatcggg ttagatcggc ttaaagtact
    20881 ccatatcaat gattctaaaa atccgcaagg ttcgcataaa gaccggcacg ccaatattgg
    20941 ttttggaaca atcggattcg acacgctgaa taagatcgtc catgatccaa tgtttgacaa
    21001 tatttcgaaa atcttggaaa ctccctatgt cggcaaagat aaaaagaaag cttacgcacc
    21061 atatggaaaa gaaatcgcca tgttcaaagc acaaatattc gatccagaag tgtttcctga
    21121 gttattagca gaagaagtga tactctaaga ttttctatct gacagcagca aaaaaggacc
    21181 aggcacattg ccttgtcctt ttttgtttaa gaaacaaagg agtgcttttt gcagtctttt
    21241 tcatcatgca tcttctcccc cctcttttta aatttagaca aacagggtat actggtagaa
    21301 aagtaaaaaa acgaaaagtt tcacaagcaa gtggcaaaac gtgattggaa ggacgaaaag
    21361 atgctgaaca ctttaaaacc cttgatcaac caactaaaaa agaaacatac atactttatt
    21421 cttggcatag ccctattatt tacaattatt cgtttgtatt tatatagtaa agcaatctat
    21481 ggaacagaca tgtcggcaac ctatgatgac cagctgctga ttcgctatgc tcaaaatatt
    21541 ttggacggta aatggctagg ggagtatacg actacaacac tttccaaagg aatctcctac
    21601 agcttatttt tagtacttgc acataaactg catctttctt atgcagtttt gttcggcatg
    21661 ttcagtattt ttgccagtat attggttgca ctcgcgttta aaccgatcgt gaagaacaag
    21721 tatcttcttt taagtttcta tttttatttt ttgttttctc cgattagttt tacacatgaa
    21781 tattccactc gaacgtatcg taatgccctc gtgattccgg ctgttgagat cattatcgct
    21841 tgtttactag ctatttatta ccgtaaatat agttccagca aaaaaatgct gccgtggttt
    21901 ttagggctag ctgtttcttt tcctttcttt tggttcattc gcgaagattc catctggctt
    21961 cttcctttta ctgtagtcgc gttaggcatc agtttcgtcc agatcttgct aggacaagac
    22021 ttttctttca aagaagcaaa gaagttaaaa gaacgaccat ttctcctttc gaaacaagaa
    22081 tggctgaaac tttcattgtt tttactccct ctagtcggtt tctccatcgt ctatcagtgg
    22141 atcgaatata aaaacgagac aacatatagt attgccgcca tcaatgaccg ttcgagtggc
    22201 gaatttggac gtttgatgaa acagctgatc cgaatagatg acgaaacgaa cttaaataaa
    22261 gaaaacagtg agatatgggt ctcgcatgct gcattaaata aagcattaga cgcatctcct
    22321 acatttcatg ctgtttctac tcgtattgac gaattgtata cgactcatgc gtggacccaa
    22381 ggtggaaaag taaaagaatt accaggagat atcatttttt gggcattgcg agatgtggta
    22441 agcgaatctg gttattacca aaacaatgca aaagaaacca atgatttttg gaaaaaagtc
    22501 aatcaagaat tagaagaagc ctatcaaaag ggaactatca aaaagaaaaa agaattctat
    22561 ctgatgggat caggggatgg aaagacgatg aatgatctgc caatcgtatt tgcttttctg
    22621 aaatcaggat atgcctatgc atggcgatac aaagatttcc atcaaggggg gaattatagt
    22681 ttcggtacgc aagaacaagt cgaacaggcc caagaattat tgaatcttcc actaatggat
    22741 aattggatcg atagcagtga tccgagaaca cctgatttcc agttgacaaa aacagcaaaa
    22801 gtcgcgaatg tcatgataaa aatttaccaa gttctggcca ttcccgtgct gattgcttca
    22861 atagcaggga tattacttat gatactagga accgcatttg caaaagctga tcgtgcctat
    22921 tatagttcct ctttgattgt agtcaccgga ttaatactga cacaattggt ttttcttttc
    22981 ggcgtctcgt ggttttgttc ttatgcgcca gaaaaaaagg attatttttt aagtgtctac
    23041 actggcgcag gcgtgccatt aacgcaattc atcgtagtaa caagcatgct agttttcagt
    23101 aaattgaatc tgaaaaaagc tttatcttcc aaataaaaac atactaagat tagaggagaa
    23161 catcattgac gaatgatgtt ctcctctatt ttctattttt agattatagt gaagagtgaa
    23221 agaaagttcg aacaaagcct tgaggacta
//
LOCUS       DADQDV010000045        22771 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.045, whole genome shotgun sequence.
ACCESSION   DADQDV010000045 DADQDV010000000
VERSION     DADQDV010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22771
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.045"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            3..371
                     /locus_tag="J8S10_001836"
     CDS             3..371
                     /locus_tag="J8S10_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HAZ9630420.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            551..1492
                     /locus_tag="J8S10_001837"
     CDS             551..1492
                     /locus_tag="J8S10_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HAZ9630421.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            1561..2292
                     /locus_tag="J8S10_001838"
     CDS             1561..2292
                     /locus_tag="J8S10_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HAZ9630422.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            2436..4616
                     /locus_tag="J8S10_001839"
     CDS             2436..4616
                     /locus_tag="J8S10_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HAZ9630423.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            4636..5118
                     /locus_tag="J8S10_001840"
     CDS             4636..5118
                     /locus_tag="J8S10_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HAZ9630424.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            5134..5895
                     /locus_tag="J8S10_001841"
     CDS             5134..5895
                     /locus_tag="J8S10_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HAZ9630425.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            6026..7360
                     /locus_tag="J8S10_001842"
     CDS             6026..7360
                     /locus_tag="J8S10_001842"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HAZ9630426.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            7667..8152
                     /locus_tag="J8S10_001843"
     CDS             7667..8152
                     /locus_tag="J8S10_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HAZ9630427.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            8145..8828
                     /locus_tag="J8S10_001844"
     CDS             8145..8828
                     /locus_tag="J8S10_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HAZ9630428.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            8954..11599
                     /gene="polA"
                     /locus_tag="J8S10_001845"
     CDS             8954..11599
                     /gene="polA"
                     /locus_tag="J8S10_001845"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HAZ9630429.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            11644..12480
                     /gene="mutM"
                     /locus_tag="J8S10_001846"
     CDS             11644..12480
                     /gene="mutM"
                     /locus_tag="J8S10_001846"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HAZ9630430.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            12444..13073
                     /locus_tag="J8S10_001847"
     CDS             12444..13073
                     /locus_tag="J8S10_001847"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HAZ9630431.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEKLVGQIENWLFANRFL"
     gene            13125..13457
                     /locus_tag="J8S10_001848"
     CDS             13125..13457
                     /locus_tag="J8S10_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HAZ9630432.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            13769..14260
                     /gene="nrdR"
                     /locus_tag="J8S10_001849"
     CDS             13769..14260
                     /gene="nrdR"
                     /locus_tag="J8S10_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HAZ9630433.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            14283..15656
                     /locus_tag="J8S10_001850"
     CDS             14283..15656
                     /locus_tag="J8S10_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Replication initiation and membrane attachment"
                     /protein_id="HAZ9630434.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            15656..16582
                     /gene="dnaI"
                     /locus_tag="J8S10_001851"
     CDS             15656..16582
                     /gene="dnaI"
                     /locus_tag="J8S10_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HAZ9630435.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            16711..17151
                     /locus_tag="J8S10_001852"
     CDS             16711..17151
                     /locus_tag="J8S10_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HAZ9630436.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            17295..17996
                     /locus_tag="J8S10_001853"
     CDS             17295..17996
                     /locus_tag="J8S10_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HAZ9630437.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            17993..19114
                     /locus_tag="J8S10_001854"
     CDS             17993..19114
                     /locus_tag="J8S10_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HAZ9630438.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            19129..20361
                     /gene="pepT"
                     /locus_tag="J8S10_001855"
     CDS             19129..20361
                     /gene="pepT"
                     /locus_tag="J8S10_001855"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HAZ9630439.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            20493..21401
                     /locus_tag="J8S10_001856"
     CDS             20493..21401
                     /locus_tag="J8S10_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HAZ9630440.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            21436..21708
                     /locus_tag="J8S10_001857"
     CDS             21436..21708
                     /locus_tag="J8S10_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HAZ9630441.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            21719..22765
                     /locus_tag="J8S10_001858"
     CDS             21719..22765
                     /locus_tag="J8S10_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HAZ9630442.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
BASE COUNT         7674 a         3974 c         5005 g         6118 t
ORIGIN      
        1 agatgtttac gaatgaaata aaaatcatgc tttatgtgga cgatgtagaa aaaaatgcaa
       61 cgttttggag agcagttggc tttgcggaaa aagatcgtca agaaatggat gggacgctta
      121 taattgaagt aggagttgag gacagtcaaa cctcatttct gttatatgat cgagcatttg
      181 ttgagtccca ttcacctggc acagctacta gtgccccatc tttgatgttt tacagtaaag
      241 atatctttgg actatataaa aaaatgcaga cgcaatcagt cacattaggt gatatggtac
      301 agcttggaga agaatatgtc tttaactttg ctgatcccga tggcaactac tttgcggtta
      361 caggtaaata atagaaataa agactttgtt tttctgtgcg aaacaggaaa gcgaagtctt
      421 tttaattcaa ataataatat tatgtaaaca aaaaactttc catgcgtaat tatacacaag
      481 caaataaatc gtcaaatgcg aacgccttct ttatactgtt taggaacgaa aagaaggaag
      541 gaagaaatac atggattatc aagtactgct ttattacaat tatacaaaaa tcgaagaacc
      601 agaggaattt gccaaaaatc atttagcctt ttgcaaatct ttggatctta aaggtcgtat
      661 tctagtagct gaagaaggaa taaatggtac tgtgtctgga accgttgaaa acacgactgc
      721 ctatatgaaa gcaatgaaag ctgatcctcg atttgctgat acgatgttca agatcgatcc
      781 aagcgaagga catgccttta agaagatgtt tgtaagatac cgtccagagc ttgtaagttt
      841 aaagctagaa gaggacattg atccaaacca agtgacaggt gcctatcttt caccgcaaga
      901 atttaaagaa gctattttag atgaacagac agtggtgatt gatgcacgga atgattatga
      961 atatgacttg ggacattttc gaggggctgt acgcccagat atacgcagtt ttcgagagct
     1021 tccagactgg atccgcgagc acaaagaaga atttatggaa aaacgggtag tgacctactg
     1081 tactggtggc attcgttgcg agaagttttc tggttggctt gtccgtgaag gattcaaaga
     1141 tgtcggacag ctgcatggcg gtattgctac ttatggtaag gatcctgaag tccaaggaga
     1201 attatgggac ggcaagatgt atgtgtttga tgaacggatc gctgtcgata tcaaccaagt
     1261 agataaacaa atcgtcggtc gcgactggtt tgacggaaca ccatgtgaac gatatatcaa
     1321 ttgtagcaat cctgagtgca atcgtcagat tcttgcttcc attgaaaatg aagaaaaaca
     1381 tttaggagca tgtagcatag agtgtgcgaa acatccgcgc aatcgctatg ttcaagacca
     1441 tggaatctct ccagaagaag cagaactgcg gtttacagct ttaattaaat agaaaacaat
     1501 agttttgatt gtcgaccatt tccaatatgc gctatactag cgttgaggat ggtgatccac
     1561 atgaaatcat tgatttatgc tattggggat gtccatggca aacatgagct ttttgaaaaa
     1621 cttattcact attatgatcc aaagatccat cagcttgttt tattagggga tctcaatgat
     1681 cgaggtcctc gtacaaaaga atgtttttta ttaggaaagc aattagtcga agaaacagga
     1741 gccatttacc tccggggaaa ccatgaagaa tattttttgc aatttctgca atcaccggag
     1801 gactggtatg cgccttatat gagaaatggt ggaaaagaaa cgtttgaaag cctgattcac
     1861 ccaggggcat cggaggaata ctccccaact gaaatctcga tgatgatcca atcgagatat
     1921 tcagaactga ttaaattttt agtccagcgc cccttgtatt atgaatggga aaattatctt
     1981 tttgtccatg ccggtgtgga tttgacaaag aaagactggc gtaagacaag tctaagagac
     2041 tttatttgga taagggaacc atttcatgaa gggaaaaaca atacaggtaa gacaattgta
     2101 tttggacata cgattacacc aatgctccat ggagatatgc agacaacaga cctctggatt
     2161 caggatcata aaatcggaat ggacggtggg gctgtattcg gagggtcatt gcatggggtt
     2221 gtttttgaca aggaaggtat tcttcaagat attgaatatc agaacaacga aggaccttgg
     2281 catggaatct gactaatgga aagaatgaag gagctgtgac tttgttgcgg ctctttttat
     2341 ttttatagag aatattgttt ctttcagtag tttaacccag gataaaaagt atgatagaat
     2401 aaagaagcaa tttttagcag aaaagaggca ttttaatgac ggaaaatttg aaccagacga
     2461 tcattcagct tgtacaaaaa gaactttcag actatcgtcc taagcagttg actactgtac
     2521 ttaatttgtt aaatgaagga aacactgttc cttttatcgc gcgttaccga aaagaaatga
     2581 ctggaagtct tgatgaagtc cagattcgtg aaatcgaaga gcggtatgcc tatcttgaaa
     2641 acttagaaaa acgtaaaact gaagtgattc ggctaatcga tgaacaaggg aaactgactc
     2701 ccgagttaga agcagaaatc acccaagccg tgaaaatgca acaagtggaa gatttgtatc
     2761 gtccatacaa acaaaaacga cggacaaaag caacgattgc taaagaaaaa ggacttgaac
     2821 cactcgcgaa gtggctgatg cagcttacag atggagaggt gcaatctgaa gcagaaaaat
     2881 atattgacaa agaaaaagaa gtctcttctg ccgaagaagc gttgcacggt gctcatgaga
     2941 ttattgctga acaagtcagc gataatgcaa aatttcggac ttggattcgg tcttatacgt
     3001 ataacaaagg tatgtatgtc agcaatgtca aggatgagca agcagatgaa aaaggcgtat
     3061 atgaaatgta ttatgacttt gcagaacccg tccataaaat ggtttctcat cgaatattag
     3121 ctactaatcg tggagaaaaa gaagatattc tgaaagtatt ctttcaagta gatgaagcag
     3181 caattttagc ttacttggat cgccaaatag tcaaaaatcc tgcctctcct tcttcttcat
     3241 tcgtcagaga agcctatcag gatagttata aacgctttat tcagccagca atcgagcgag
     3301 aactgcgcaa tgaattgact gaaaaggcag atgagcaagc aatcgctatt ttcggcgaaa
     3361 acctccgtaa tcttttgttg caaccgccac taaaaggtaa agttgtcctg ggatttgatc
     3421 cggcttatcg tactggatgt aaactagcag tcgtagatgc gacagggaaa gttttagcaa
     3481 tcgaagttat ttatcctcat aaacctgcag cgcaagcaaa aagagaagct gctggaccag
     3541 cttttatcca attaattaat aaatatcaag tagatatggt agctatcgga aatggtacag
     3601 ccagtcggga atctgaactt tttgtggctg agcagttgaa atccgccgac cataaaacct
     3661 attacgctat cgtcaacgaa gcaggcgctt ctgtttactc cgctagcgaa attgcacgaa
     3721 aagaatttcc gcatctacaa gttgaagaaa gaagtgctgt ttctattgcc cgtcgcctgc
     3781 aagatccttt agctgaatta gtcaaaatcg atcctaaagc tgtcggagta ggccagtacc
     3841 aacatgacgt ttctcaaaaa cgtttggctg aacaattgga ttttgttgtg gaaacagcgg
     3901 ttaaccaagt aggtgtggat gtgaatacag caagcccgca gctcttgcag catatatcag
     3961 gattgaataa aacaactgcc caaaacattg tcatttatcg tgaagaaaac ggagaattca
     4021 ccgcacgaac tcaattgaaa aaagtgccac gcttaggacc aaaagcatat gaacaagcaa
     4081 tcggattctt gcgagtccct ggtgggaaaa acattttgga caacacaggt atccatcccg
     4141 aaagttattc tattgcaaaa gaaatattaa cttcagtcca actttcagaa aaagagcttg
     4201 gtacagaaga agcagtagaa aaattgacac gattatccgt agagaaactg gctgaaagcc
     4261 tatcagtcgg agaagaaacg ttagccgata ttttagctgg gctgacacaa cctggacgag
     4321 atatgcgtga tgagatgcca gcgcccttat tacgtacaga tgtattgagt atggaagact
     4381 tgaaaccagg gatggaattg actggaacgg tccgtaatgt cattgacttc ggcgcatttg
     4441 ttgatatcgg tgtgaagcaa gacggacttg tccatatatc gaaactcagc aaaaaattcg
     4501 tcaagcatcc tacagatgtc gtgtcagtag gagatatcgt aacagtttgg atagaacaag
     4561 tcgatacgaa aaaaggcaga atcagtttga cgatgctttc cccttatgaa gagtaacaat
     4621 gaggagtaac aaaaattgac acaagaagaa ctgcagcagt tagtagaaga gatatcatta
     4681 aaaagcttcc agcttccttt caagcaccaa gcaatgttca atccacgctt acgtacaact
     4741 ggcgggcgct atcatttaaa cgatcatcat ttagatttta atgcgaagct atttgaagag
     4801 tcagacgaag agacgattgc aggaatcatc aaacatgaac tttgccatta tcatcttcat
     4861 ctagctggaa gagggtatca gcataaagat atggatttca agtatctttt gaaaaaaaca
     4921 ggagggttgc gctatgcacc agccttgacg aagaaacaga taaagatgga gtattatcga
     4981 tgccaagatt gttctgccac gatctgccgc aagagaagaa tcgatgtacg caaatatcgt
     5041 tgtggaagat gtcatggaga aatcaaatgg attgagacaa aaagagaaga ctttaatgaa
     5101 gcacaaaaaa tcagatgaaa ggatagaagg cctttggaaa aaagtgagca gaggaatcta
     5161 aaagactgga atcagctatt aaatttttta gccgcacctg aagagggaaa ttttgaggaa
     5221 ctgacggcac ctacacttat tttagctgga aactgtcttc ctatcttagc tgataaagca
     5281 gcacaaatgt atttaaatgg ccaagtagat caattgtttt tggtcggagg ggtggggcat
     5341 gcgactagaa tcctttatga gaattttgaa aagcaaggat ttcattttga agatggcatg
     5401 agtgaaagtg aaatctgtcg tcagtatcta aaagaagtct atgatttgcc cgataaggct
     5461 tttctgatag aatcgaagtc tacaaattct ggagagaacg ccactttttc actggagatt
     5521 cttcattcct taggagctgt accagaaaaa atcttattga tgaatgatcc gacactgcaa
     5581 cgcaggactc gagcaacttt tgagaaagta tggcaaaatg aacaaactat tttcgcgaat
     5641 gctgtgccat ttgtgccgga aatccttcac ttttctgaag agatcatctt tacagcaaaa
     5701 gaactgaatc atcaatggcc taaggaatat ttccatgcgc tagtattagg agaaatggaa
     5761 cgtctccatg acgatgagaa cggctatggt ccgaaaggaa aagattttat tcctcacatt
     5821 gatatatcag aggaagtttg gtcttcttac accagaatta aagagtcaat aaaaacggat
     5881 ttttctcgta cttgaccatt ttagcaagcg aatcctcctt tccaaataaa tttggttgaa
     5941 attttcaatc gtttataaga taatgaggag cgtgttgaat gtaatagcta aaagaatgga
     6001 cgctagataa gagaagagga ttcaaatgga aaatcaaaat aaattgtatc attttgttgg
     6061 tatcaaaggt tcaggaatga gctccttggc tcttgtttta catgaacaag gtctaaatgt
     6121 ccaaggatca gacattgaaa aatatttctt tacacaaaga gatttagaaa aagcaaatat
     6181 cacgattctg ccatttaacg cagataatgt aaaaccaggg atgacgatca ttgcaggaaa
     6241 tgcatttcct gattcacatg aagaaatcca gcgagcaaaa gaattaggtt tggaagtgat
     6301 tcgctatcac gactttattg gtcattttat ccaaaattat acgagtatcg ctgtaacagg
     6361 ctctcacgga aaaacaagta cgactggact gctctctcat gtattgagtg gtgtccgtcc
     6421 aacaagttat ctaattggag atggaacagg acatggtgat ccgcaagcgg aattcttttc
     6481 atttgaggcc tgtgaatatc gccgtcattt ccttgcctat tcaccagact atgcaatcat
     6541 gaccaatatc gattttgatc atccggatta ttatacaagt atcgacgatg tatttacagc
     6601 tttccaaaca atggctggac aagtgaaaaa agctattttt gcgtatggtg acgatgctta
     6661 tttacgcaaa ttaaaagcaa atgtgccgat ttattattat ggtgtcacag aaaacgatga
     6721 tatccaagca cgaaacatcg aacgcacaac ttctggttct gcttttgatg tctatcatgg
     6781 ggatgaattt gttgggcact tcactgtacc agcattcggt aaacacaata tcttaaatgc
     6841 tttaggtgtt attgcagtag cttatttcga aaaactggat ctgaaagaag ttgcagaaga
     6901 aatgctgact ttcccaggag taaaacgtcg attcagtgaa aagatcgtag cagacatgac
     6961 cgtagtcgat gattatgcgc atcaccctgc agagatcaaa gcaacgattg atggcgcacg
     7021 ccaaaaatat ccagataaag aaataattgc agttttccaa ccccatacgt ttacgcgtac
     7081 gattgcattg atggatgaat ttgcagaagc acttgattta gctgataaag tttacttatg
     7141 cgatattttt ggttcggctc gggaagaaca aggaaacgtt aagattgaag accttggagc
     7201 gaaaatcaaa aaaggtggag aagtcatcaa agaaaataat gtatctccat tgttagatta
     7261 tcatgatgca gtagtaatct tcatgggtgc tggagatgtt caaaaatttg aacaagcgta
     7321 tgaaaaactt ttaagcagca cgacgaaaaa tgtactgtaa tacaattact gcagtgtcct
     7381 tataaaaata gaaagagggg gagtggcaaa aatcttgcca agcccccttt tttgcaactt
     7441 atgataaacg gtgttcaaaa gcttgcatct gcggtaataa gcccaatcaa atcaaaaaca
     7501 tgagaagctg ttttttcttg gctgttctta ttatttgatg caggacagct ttttcacgac
     7561 ctctgtaaac tataggaatc tgttaaatca agggagcaga acttgccttt tacgctactt
     7621 ttggtacaat aatgtatgat taaaaataaa ctggagggtt tctatcttga acataggtaa
     7681 gccgagaaaa ctaggaaaaa caataaatga aatcgaggaa ggcgactcgt tatccttaac
     7741 agaatctatt gaagataacc agcttttgct gtatttggga ttgacgaatg atgcaaatcc
     7801 tttgtatatc caacatgact ttgcacaaaa aacagaatat caacagccaa tcgttccatc
     7861 agtgatgctg atggggatca tcacaagtgc aatttcaaag catcttcctg gaccaggatc
     7921 acatgttgtc aatttttctg tcaattttat tgaaccggtt ttccattatg aaacactgac
     7981 ttttcagttt gaggtcataa aagtagataa gatgaaggat gtggtgacga tttctgtaga
     8041 agcggagaat acgaacgaag atcgtgtgtt ggatgctgtc gttatggtcc aaccgccaca
     8101 agttcctgaa ttggaaatag caatcgaaag tgaaggtgaa ttgaatgaat aatccaagta
     8161 catcaatgtc aggtatcaat cgtttttatg caaaagttta tggattttta ggtatgggac
     8221 ttgcccttag tgcagtcact tcttacttgg ctctttgggt atttcctttg caattagcaa
     8281 cttttatcaa taattttcca ctaggctttg tgggtctgtg gatcgttgaa ctgattttag
     8341 taatggttct aggcgtaaaa gcacaaaaga atccgagctt agcaatcggt ggatttattg
     8401 cctactctct tttgaatggc ataacattag cggttactct tgcatactac gatattggaa
     8461 cagtaacgca agctttcttg acagctactt tgatgttcat ggggatgtct gttgtcggag
     8521 taacaacaaa aagagatctt agcggggttg gaagagcagg acaggcagct ttaatcggag
     8581 tgatcattgc actagtcttg aacatcttca ttttgagaag tagcgtagtt gagctgttca
     8641 tctccctact gttagtcgtc atctttgcag ggattacagc ttatgataac caaagcatcc
     8701 gtaatatcta tgtccagaca aacggaacag cacatagtgg aattgctgta ttcatggcat
     8761 tgaagctgta tttggacttt atcaacttgt tcttggcgtt tctgagaatc tttggacgga
     8821 acaactaaaa aagaaaaaaa ttcatcagtt ggggctatac cgaattattt ggtatggtcc
     8881 cgctttttct tttcgcattc cgcaggattc tttgttagaa tgaataagaa ctttacagta
     8941 aggagttaag aagatgacaa aaaataaatt attactcgtt gatgggaaca gtgtggcttt
     9001 tcgcgcattc tttgcgcttc acaattctct tgaacgtttc aaaaatagaa acggtcttca
     9061 tacaaatgca atctatgcat tcaatacgat gtttgaaaat gttatgcaaa aagagcaacc
     9121 gactcatgtt ctggttgcgt tcgatgcagg aaaaacgact tttcggacag aaatgtatgc
     9181 ggagtacaaa ggtggaagat ccaaaacacc tggcgaattc aaagaacaaa tgccatatat
     9241 acgtgatttg ttgacaggac taggggtaca gtattacgaa ttgcccaatt atgaagcaga
     9301 tgatattatc ggtactttgg cagaaaaagt agacaaagat caatttgatg tcgtcgtgct
     9361 ttcaggtgat cgggatttga ctcaattagc tagtaaagaa gtaaaagtgg atatcactgt
     9421 aaaaggtgtc agcgatatcg aaagctatac accagaacat gtagcggaaa aatatgatgg
     9481 gttgacgcca aaacagatta ttgacatgaa gggactagcc ggagatgcct ctgacaatat
     9541 ccccggtgtg actaaaatcg gtgaaaaaac agctatcaag ctattgaaac aatatggctc
     9601 agtcgaagga atttatgaac atatcgatga aatgaagcaa agcaaaatga aagaaaatct
     9661 gataaatgac aaagagcagg ctttcttatc gaaaaaattg gcgaccatca atacttcagc
     9721 gcctgtggat gtctctatcg actcattgaa gtatgaaggg aaaaatctcg ataaactcgt
     9781 tccgttttat aaagaaatgg atttcaatca gttcctttct aaattgaata tcgtagaaga
     9841 agaagtaaaa atggatgata ttttgtttga agtcgttcat gaattcaaag aggaaatgtt
     9901 tactacggat atggcgttgt acgtggaaat gatgggcgac aattatcata cagaggaaat
     9961 cgtcggagta gcgtggggga cagaaaagaa aatttatgtc acgaacgatc tatctgtatt
    10021 cgaaaaccga gcgttccatt cttggatcac tgatccgact cggctgaaaa aagtatatga
    10081 tgcgaaacga acttatgttg ctttaaaccg ctatactgga aaaacgaaag gaatcgattt
    10141 tgatgtcttg ctaggtgcat accttctcga tacgaatgaa aaaagcacag atatcgaagg
    10201 aatagctgct cattacggat acaacgatat ccaatcagat gaagctgtat acggcaaagg
    10261 ggcgaaaaaa ggtttaccag aagaagagga actctttttt gctcatttag cgcgaaaagt
    10321 agctgcaatc aatgcgttga caccaaaatt gagccaagaa ctggcagaaa aaaaccaaga
    10381 agatcttttc cggaaaatgg aactgccatt gtctatcatt ttggcagaga tggaaataag
    10441 cgggatcaaa gtagatgcga ctcgcttaca agaaatgaag ggcgagttct ctgctcgctt
    10501 aagagagatc gaacaaaaaa tctacgaaga agccggcgaa gaattcaatt tgaattcacc
    10561 aaagcaatta ggagtgatct tatttgaaaa aatgggatta cccgttatca aaaaaacaaa
    10621 aactggatat tccacagccg tagatgtact ggaacagctt cgtgaacaag caccaatcgt
    10681 agaggatatc ctcacctatc gtcaaattgc aaaaattcaa tctacctatg tcgagggact
    10741 gctgaaagtg atccaatcag atggaaaagt gcatacccgt tatgtccaga cattgaccca
    10801 aacaggacga ttaagctctg ttgatcctaa tttgcagaac atcccgattc gattagatga
    10861 agggagaaag atacgtcagg catttgttcc tagagaaaaa gactggctga tttattcttc
    10921 tgactattca caaatcgagt tacgcgtact tgcgcatatc tcaaatgatg aacatttgaa
    10981 agctgccttc ctagaaggtc aagatatcca tgccagcaca gcgatgcgtg tatttggaat
    11041 cgaaaaggca gaggatgtca caccaaatat gcgtaggcag gcaaaagcag tgaattttgg
    11101 tatcgtgtat ggcatctctg attacggact ttcacaaaat ctaggaatca gccgaaaagc
    11161 agcacagcaa tacatcgata cgtactttga aaaataccca ggtgtcaaag aatatatgga
    11221 aagaatcgta cgcgaagcaa aagaccaagg ctacgtcgaa acgctgtatc accgccgtcg
    11281 atatctgcca gacatcaatt caagaaatta caatatccgt tcttttgcgg aacgaacagc
    11341 tatcaataca ccaatccaag gaagtgctgc tgatattttg aaaatcgcga tgatcgaatt
    11401 ggataaacga ttaaaagaaa caggtcttca agctacgatg ctgttacaag ttcatgatga
    11461 acttgtcttc gaggtaccgg aaaaagaact tgaatcatta gataaattgg tgaaggaagt
    11521 tatggaacaa gctgtttctc ttcatgtacc actgatcact gacagcagtt ggggaaaaac
    11581 gtggtacgaa gcaaaataaa cattgtttaa gacagagcaa tataatgaag gtgaaaagaa
    11641 aaaatgccag aattaccaga agtagaaacc gttcgtaaag gattggaacg gttagtagta
    11701 ggaaaaacga ttcaaaaagt tcaggtcttg tggcccaaga tcatcgagca accagagaca
    11761 cccatctttg aggcttctct tgttggcgaa accatccaat ccattggacg tagagggaag
    11821 tttttaattt ttcatctcga tcattgtgaa ctgatctcac acttgcgaat ggaaggaaaa
    11881 tatcaattta cgaaagaaaa tacaccaatc gataaacata cgcatgtact tttctttttt
    11941 gaggatggaa gccaacttcg ctacaacgat gtacgaaaat ttggtcgtat gacaatcgtc
    12001 gaaaaaggag caagtgcaac ttaccgagga atcatgaaat tgggacctga gcctttgcca
    12061 gatagcttct tattagcaga tttcgcaaat ggactgaaaa agtcccacaa agcaatcaag
    12121 ccattgctgc tagaccaacg tctagtgact ggtctaggta atatttatgt agatgaagca
    12181 ttatgggaag cgaagatcca tccagaacaa ccggcgaaca cactgcgccc caaagaggta
    12241 gaacaattac gtctatcgat cattgatgtt ttggatcgtg caatagaagc cggaggtacc
    12301 acgattcgca gttatttgaa tgcattagga gaatcaggcg gatttcaagt agcactgcat
    12361 gtctatcagc aaactggcaa accatgtata cgttgtggaa cgccgatcgt gaaaacaaaa
    12421 gtggcacaaa gggggacgca ctattgtccg aattgtcaaa ggctaaaaat cgcaaagtag
    12481 gatttgtttt aggtttgacg ggtggaatag ctaccggtaa aagtacggca gccaaagtct
    12541 ttcagtctca tggatttcct ttgatcgatg gcgatgtgat tgccagagaa actgttgagc
    12601 ctggaacgct tgctctgagg aaaattgtat cagtgtttgg ccaagaggta ttgcagcctg
    12661 atgggcaact agatcgaggg aaacttggga tgattgtttt tccatcaaag gaaaaacggc
    12721 aaaaacttga tcagctatta gatccgttta tccgaaaagc gataaaagat caaatcgcct
    12781 ctctaagttc caatcatcct ttagtaattg tagatatccc attgctctac gaaggtcatt
    12841 atgaccacta tatggatgca gtagctgtcg tttatactac gccagaaact cagcttcagc
    12901 gtttgatgaa acgtaatcaa ctgacgctag aacaagcgca gcagagaatt agtagtcaac
    12961 ttccaatcga agaaaaaaag cagcgtgcgg atattttgtt cgacaacaat ggaacaaaag
    13021 aaaaacttgt gggacaaatc gaaaattggc tttttgctaa tcgctttctt tgagtatctg
    13081 tgtcaatttt gctatcctga gtatatagaa agtgagggat agcgatggga tcattaaaaa
    13141 atcaaaagga taaagtcgta ggtaacgcaa aagaaaaaat cggcgagatg ctcaataaag
    13201 aaaatctaat cgatgaaggt cgtacgcaat cagaaacagc agaagaaaaa gaaaagcagt
    13261 accaagcaag aatcgatgaa atagaagacc agcaggcaga agaagaagcg aagcggcaag
    13321 atttgactca agaacgaaaa aatccgacac ctgatcgtag taaaacaccg ctcccagaaa
    13381 gtgaccacat tcccgatgag caaaaaatcg aggaacagcg aatgaaacac tatacaggaa
    13441 tcgaagagaa gttataaaat agtaaaaaat cgagatgtga cttgaagcag atgagaaggt
    13501 gttcatctgc ttcaagtttt ttgtgctaga tgactaaatc agcttttgtg taagttattt
    13561 ctcagtaatc aaggtgatca gtattggaaa attgaaattt agtaaggaca ggggacacaa
    13621 ttacgcatga aagtagaaaa aattgttctt atatccgtgt tttttgggta ggacagtcgc
    13681 gtttgtgatt tgtttcgtgt tataatacaa ctagttgtaa agaaagacac atcctttata
    13741 taaaatgcga tgcaagaggt gagacaaaat gagatgtccc agatgtcaac ataataattc
    13801 acgagtaatc gacagccgtc aagcagatga tggacgtgcg atccgtcgcc gtcgcgaatg
    13861 tgagaattgt tcgttccgat tcactacatt tgaacgaatt gaagctgctc cgttattagt
    13921 aatcaagaaa aacggggaac gcgaagagtt caatcgcgat aaaattttaa gaggactcat
    13981 ccgttcagca gaaaaaagac ctgtagctat ggaacaaatg gaacaaatcg tcaaccatgt
    14041 cgaaaaccgc gtacgcagtc tcggagaaaa cgaagtatcg acgaatctaa ttggtgaata
    14101 tgtgatggaa gatttagttg atttagacga aatcgcttat attcgttttg caagtgttta
    14161 tcgccagttc aaagatatgt ctgttttctt aaaagagttg caagatatcg tggataaagc
    14221 aaaagaaaat aataaagaga ataataaaga aaacaattaa gaaacaaaaa ggaggcattt
    14281 ccttggaaaa tgcttggaaa gagcttcaac caaaaaatat ttaccaagga agaaaagcgg
    14341 ctccgctgag agaagacagc aagaacgcct tgctgtatct ttatcagcca ctaatcggcg
    14401 gagaagcctt gagtatctat ttcaccctgt tatcagaaat ctctcaagaa tctggcaaag
    14461 gtcctgaagg gatgcatgca gatctgctta gtagtctagg ctgcggtatc ccgcaatttt
    14521 atgatgcaag aaaaaagcta gaaggaatcg gcttactgga tgtttatttt aaagaagata
    14581 gtgatctggg acctcgtttt atttatgagc tgttagaacc actcattcct aaagcatttt
    14641 tcaaagactc tgttctggct tttcttcttc tggaaaaagt tggtgaacga cgattccaga
    14701 agcttaccca attctttgaa cctaaaaggc atacagcaga gggatatcaa aaaatcacaa
    14761 aaaaattttt agatgtttat cgcttcaatg aagcagtgta cgctgctaat caagaaaaca
    14821 tcgaatcgct gaataaatct tttgaagaat ctgaatcagt agcattactt gaagcagatt
    14881 cgacattcga ttggcagttt ttgaatgatt ggctggcaaa aaaacatatt gcaagtcttg
    14941 atgatccaat catcaaacaa gtcgacatgt atcatcagct ttacggtttc gatgaattga
    15001 cacttggcga actgatcagt caatcttatg actttagtga acaaaaagta tctgaaaaag
    15061 aactgcaaaa agccattttg gcaatgcaga gacgtccggt gaagcaaaca aaagaaacag
    15121 ttgcggtttc tgaaaacagt aatgaaccct cgtcaaacga acatttgaca aacgcagcgc
    15181 ttcagctgat aaaagaagca cagagcattc caccgatgaa atatctggaa gcaatcaagt
    15241 cagaaaaagg cggatatgtt tctaaacaag aaaactggtt actgcaagat cttgtttctc
    15301 aatcaggtct ttccagtagc gtgatcaatg ttttgctgaa ttatgtacta gtgatcaaga
    15361 ataatgctag cttaaatgcc agttatgtaa atacagtggc aaatgaatgg gcacaaaaga
    15421 aaatcgccac agcagaagaa gcgatccagc acattcggca aataagtaat caagcaaaac
    15481 aatcaaaaca aaagaagcaa acaaattatc aaactggcaa gcgaaatgtt cgacgggaaa
    15541 agcttcctga ttgggtcaac cagccaaaag atgaaaaaca gatcagcagc gagaaaaaag
    15601 cagagattga ccgccgtttt aaagaatacc tggcaaaaaa ggagggtgat atctagtgga
    15661 agacgtaggc aaagaattga agaggatcat cagcaaacgc aattatcaag aaaagtatgc
    15721 tgaaatgatc gctgaagtct taaatgatgc ggatgttcaa gcttttctaa gcgcacacca
    15781 agaagaattg acacaagcgg atattgaaaa aagttacgct aaattgtatg aattcgtgca
    15841 agaaaagcgt aaatatcaaa aaaacgatcc aacgatgatc gctcccggct atgagccgaa
    15901 gctgacgttg aattttcatt atgtggatgt cacttatgta ccaacggaag cattgttagc
    15961 acggcaaaga caagaagaaa tcagaagccg agtaaaagca atggatatgc caaaagatat
    16021 tcaatcggct tcttttgaaa actttgaacg tacagatgga cgaggatatg cgagcttaga
    16081 agccctagat tttgtagaga aatatactgc tgatccaaaa gggtatcata aaggactgta
    16141 tctagtagga agttttggta ttggaaaaac atatttatta ggagcaacag cgagagaatt
    16201 agcgattgct ggattcacca cgacgctagt ccattttccg acatttgccg ttgagatgaa
    16261 acaggcaatc ggaaaagatc aagtggcaga aaagttagat gcagtgaaac gttcacctat
    16321 tttgatgatc gatgacattg gtgcagatgc gatgagtagt tggatacgag acgaagtatt
    16381 cggtgttatc cttcaatatc ggatgcagga acagttacca accttcttct catcgaattt
    16441 tacaatggat gaattggaac agcatttgtc cgtcactcaa cgtggagatg aagagccgct
    16501 aaaagcgaaa cggataatgg aacgcatacg ttatttgaca aaagaaatcg aaatgactgg
    16561 tcgcaaccga cgcaatggtt gaacagttga caagtccaac tgacatttga cctagtagta
    16621 aaagcaggtc agcgaatcat tatatggaca gaaatgaccg gagacaatca ccgcaacaag
    16681 taatgcagaa acttaaacgg aggatttttt atgagggcta ttttttctag tatatctgta
    16741 gttggtctat tttttctttt agcaggctgc ggtagcgcag atagcaacac aggttctgtt
    16801 gattcgattg atgcgggtca aacagtaaaa acaagcagta cgaaaacgga gagacaaagc
    16861 atatttgtcg gaacgattga aagtatcact caagtagaag cagaagaaga aacgcttcag
    16921 ttgaaactcg tcgatgtcat ggccaaagaa gatccagcga atatgggaac gtcattcagc
    16981 aatgacggag tgatcttaaa tgctactgct gaaaaaataa gcgtggacat aaatgaattg
    17041 aaaatcggtg acaaagtcca atttacatta gttgagatgc cgatcatgac gatgtctatc
    17101 ccaccgcaag ttcctggaga ttcgattatt gatgtttcat tgaacaaata accaataaca
    17161 ttttttcaaa aataagaaaa tgttgtttta tagaacgaaa aggtatattt tttaaggaga
    17221 tatgggaatt tttttattcc tagtctcctt attttatttg gaaaatgcta taattatcta
    17281 gaaggagtga agctatgaac catttagatt tatctcagcg cttagccgca gtgggtgact
    17341 ttgtccctga atccgctcgt ttagcagaca ttggatcaga tcacgcttac ttacccgttg
    17401 cattgatatt aagaggaaaa atcgaatatg cagttgctgg tgaagtcgtt caaggtcctt
    17461 atgaatcagc acgtaagcaa gtcaaaaaag atggattaga agaccgtatc accgtacgcc
    17521 ttgcaaatgg tctagatgct atccagccac aagatggtat tacagctgtc acgattgcgg
    17581 gtatgggagg ttcactgatc cgagatatcc tagaagctgg caagttgaat caacgcttaa
    17641 gcggacaaga acgtttgatc cttcagccaa acatcggaga gcgtacatta cgatcttggc
    17701 tgcaagaaaa tcagtataaa atccaatcag aaaaaatact tgaagaaaat aaaaaaatat
    17761 atgaaatcat tgtagccgaa aaagaacaaa aaccagttac ttacaatgaa atggagctga
    17821 tgttcgggcc atttctgctt gaagagaaaa gtgagatctt caaatcaaaa tggacaagag
    17881 agcttcaaca aagaaaagct atccgtgaac agctcaaaca agcagctaat caagaggcac
    17941 gtcaaaaaca aatcgagcag gaaatccaaa tgattgagga ggttttaaag ccatgacaat
    18001 cagcggacgc actttcatcc aaaagtttga aagctattgt cctcagtggc tagctgaaga
    18061 aggagaccca gtcggactgc atatcggaac attggataag ccaatccaac gagtaatgat
    18121 gacattagac gttcgtccag aagtggtcga agaagcaatc aagaaaaaaa tcgatttgct
    18181 gattgctaaa catcctccaa tctttcgtcc tgtaaaacgg ctggttactg atcagccaca
    18241 agaaaaaatg tatgcagatt tgttgaaaca tgatattgcc gtctatgcag cacacacgaa
    18301 catggatatt atttgggatg gactgaatga ctggttttgt gaacttctcg gtattgaagt
    18361 ggagagttat ttagtaaaga ctcatgagat tcattataaa aaactggccg tttatgtacc
    18421 tgtggatcat gcacagaaaa tgcgtgaagt attagctgca gctggtgctg gtacacaagg
    18481 tgattatacc ggtacaagtt ttacctcgat tggacacggt cgatttactc cggaagctgg
    18541 tgcacaacca gcgattggga aagtagggaa gacagaacaa gttcaagagg caaaagttga
    18601 ggttattttg ccggaaacta tcgaaaaaca agtgattcaa gccatgcggt cagctcatcc
    18661 ttatgaggaa cctgcttatg atcttttcgc tatagatgaa ccagtcgaaa tgtttgggtt
    18721 aggacgagta ggtgaattgc cgcaagaaat ttctatagag gcatttgtag aacaagtaaa
    18781 agaagcgttc caactagatg gactgagaat agtccagcca aaaaatgcaa aatcctctgt
    18841 gaagcgcatt gcgatttgcg gtggaagcgg tgaaaaattt tatccgcaag caatcgccca
    18901 aagagcagat gtctatatca cgggagatat ctattatcat acggctcatg atatgcaaag
    18961 cgctgggttg attgcaattg atcccggtca ttatattgaa tcgttatgca agcaacgatt
    19021 tatcgagaaa tttgaatctt ggaaacaaga agaaaattgg gatattaact ttttcgtttc
    19081 tgaaacaaat acaaacccat ttcaatttaa ttaaaaggag agaatactat gtacgaaaat
    19141 cttttgccac gttttttacg atatgtcaaa acagaaacac gctccgatgc aacaagcaaa
    19201 acgactccat cgactcagac acaagttgct tttgcgcaag aattgaaaaa agaattagaa
    19261 gagttaggct tagctgatgt tttctataat gaagataacg gattcgttat gggaacatta
    19321 ccaagcaatg ttgatcatga agtgcgttcc attggattta tttcccacat ggatacagca
    19381 gattttaatg cagtaggagt caatccacaa atcattgaaa actatgatgg cgagtctacg
    19441 atcgtactag atgcggaaga acgctataca ttgaatacaa aagattttcc aaatttgaaa
    19501 aattatgaag gccacacatt gatcacaaca gatggcagta cattactggg agcagatgac
    19561 aaatcaggga ttgcggaaat catgactgca atggagatct tgatcaataa tccttctatc
    19621 cctcacggta ccatcaaagt ggcttttggt cctgatgaag aaatcggtgt cggagcggat
    19681 aaattcgatg ttgagcaatt cgatgtagat tttgcttata cagtcgatgg tggtccttta
    19741 ggtgagttgc agtatgaaac gtttagtgct gctcaagcaa atattacgat ccaagggaaa
    19801 aatgtacatc cagggacggc aaaagataca atgatcaatg ctctacagtt agcaatcgat
    19861 tttcataatc agcttccagc cgatgaagtt ccagaaaaaa cggaaggata cgaaggtttc
    19921 ttccatttga tggcattgga tgggaatcct gaagaagctt ctatgagtta tatcattcgc
    19981 gatcatgatc gtgaaaaatt cgaagcacgc aaagcacaaa tcacacatat ccaagaagag
    20041 ttgaatcagc gatttgatca agaacgaatc aaagtagata tgtatgatca atattacaac
    20101 atgaaagaaa tcattgaaaa agatatgagc atcgtggaat tagcgaaaca agcaatgatc
    20161 gagcttggta tctctccagt gatcgaacca gttcgtggag gaacagatgg ttcaaaaatc
    20221 tcttacatgg gtattccgac gccaaatcta tttgccggag gagaaaatat gcacggacga
    20281 ttcgaatttg tttctttaca agtaatggaa aaagcaacag acgtgattgt aaaaattgca
    20341 gaattgaaca caaagagtta aaatcgaaaa agaacagctt atgacaaggc gttcgtccca
    20401 atgatggaat gtcatctgtc taaggctaaa gggcaggaca atggaattgg ttgtcccgcc
    20461 ctcttttttg aagagtaaat aggaggtaaa gaatggaaaa gctgctagtt ttttataaca
    20521 aaagttcagg gaaagatgag ggtgagaaat tagcacgctg gtttcaagat tatgtaaaag
    20581 aaaagcagcc agaattatat gtagaactag ctgaaactgg cccatcgatt gatgatgcgg
    20641 aattagtcaa gaaagcagaa gccatagaag ctgatacttt agtaattata ggtggagacg
    20701 gcacgattca tcatatcgtc caagcgttcc aaaaaacatt atctcaatac catgtcggat
    20761 tacttccagg tggaactgtc aacaaccttg cacgtgttct tgagattccc ctcaaaaaag
    20821 aagaagctgc tgacgtgatc ctggaaggca atgtacggaa aatagactat ggtcaagtca
    20881 atgatgaagt cattatctct acactgacaa tcggaatctt agcagataca gcagtttgga
    20941 tcagtcaaga agaaaaacag cgttacggct cgtggatctt tatcaagaag ttttttaagt
    21001 tattgctgaa gaagaaaaaa tatcatttgg atttagaaac agacgaggag cattggaaag
    21061 gaaaatccca actgttgaca gtcacgatgt ctaactccgt gggcggtttt acaaattttg
    21121 acgactcagc gaccctagat gatggaaaat ttcatgtaac gatcgtacct tccttagata
    21181 ttttccgatt tattttttat ttgcctagaa tcatgagagg caaattctat acgatccccg
    21241 gcattactta tttcacagcc aaacgcatga aaatccaagc gcaggaaaaa tctgtgggca
    21301 ctcgaacgga tggagacacg acagatgatc ttccagttga attatctgtt gtatcaaaag
    21361 gattaacagt ttattcacca aagaaagaag aaaaagctta gaaatagtag ttaacagaaa
    21421 gttggaagaa gagtaatgga tgtattgtta cacaatcctt tgtggtttta ccttttcatt
    21481 gtgaattttt acttattttg tctgatgggg tatgataaac atcaggctag aactagcggc
    21541 tggcgtgttc ctgagaataa tttgatattt gtcagcctgt taggcggtgg tttgggagga
    21601 ttgatctctc gaaaagtttt ccatcataaa actcggaaaa agaagtttac tataggattc
    21661 gctgcaggtg tacttgttga tttgattctc atttattttt tccattaagg agcaggagat
    21721 gtcgtctaaa ggaacgaaaa ctaaaatcat tctgaatctg cttttgctga ttgtgatttt
    21781 tgccattatt tattatttaa tcaatcaatc atttgcagat atctttgccg aattgctgtc
    21841 taccagtgtt gttgttttgg cagcggctgt tatattaggg acagtttacc aaatcgctga
    21901 agggcgctca atcaaagaaa ttgctgaacc tttcgcgccg aattttacaa cgaaagatgg
    21961 gttcttgacc tctagctata ttgcgtttta ccgaatcgtt tcgtttggta caggaacgct
    22021 gatctcggag atttattttt ataacaaaaa aggaatgaag ctatcccagg gagcaggggt
    22081 gacagcactc catatgatta tgtacaaact ggcagtgatc acttatgcat tagctggctt
    22141 ggtcatccaa ttctctcttt tttattctaa tggtccatca atgatctggt ttatcatcgc
    22201 tggtatcctt ttgacgatcg tgattgttgc ctttttattg gcgatgtccg tcagcttgaa
    22261 tgttcaaata ttttttgtca gcttatcgaa taagttattt aaaagtgagc gtttgcggaa
    22321 atgggtggat acatgcaatc agcagatcta ctctttaagg gaaacggtcc aaaccattat
    22381 ccaagacagg actgcgctat tgcggattta tctatggaat atgttaaaac ttgtattttg
    22441 gtatgtactt ccttatttga ttctgattga aaaccatcct aaaatagatt ttctactgac
    22501 catttcgttt atcagctttg cagtagtgct ttcaggggtt attcctacgc ctgctggtat
    22561 tggttccttt gaatttgtct atttgttatt attcagacca gttgttggaa cagttgacgc
    22621 agtttcttcg cttttactgt atcgtttcag ttcctttatc ttgccatttc tctatggatt
    22681 tgtgtatgtg attgctgaac ggcgaagagt gatcaaagaa gaaataatag aagtaaaaaa
    22741 agagaataaa gaaaatcaag ggtaggtctt t
//
LOCUS       DADQDV010000046        22735 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.046, whole genome shotgun sequence.
ACCESSION   DADQDV010000046 DADQDV010000000
VERSION     DADQDV010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22735
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.046"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(27..1958)
                     /locus_tag="J8S10_001859"
     CDS             complement(27..1958)
                     /locus_tag="J8S10_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAZ9630443.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAVAEA"
     gene            complement(1976..2890)
                     /gene="pfkB"
                     /locus_tag="J8S10_001860"
     CDS             complement(1976..2890)
                     /gene="pfkB"
                     /locus_tag="J8S10_001860"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HAZ9630444.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(2887..3639)
                     /locus_tag="J8S10_001861"
     CDS             complement(2887..3639)
                     /locus_tag="J8S10_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAZ9630445.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLLNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(3799..4008)
                     /locus_tag="J8S10_001862"
     CDS             complement(3799..4008)
                     /locus_tag="J8S10_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630446.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(4019..5346)
                     /locus_tag="J8S10_001863"
                     /pseudo
     CDS             complement(4019..5346)
                     /locus_tag="J8S10_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(5711..6298)
                     /locus_tag="J8S10_001864"
     CDS             complement(5711..6298)
                     /locus_tag="J8S10_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HAZ9630447.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(6381..7631)
                     /gene="clpX"
                     /locus_tag="J8S10_001865"
     CDS             complement(6381..7631)
                     /gene="clpX"
                     /locus_tag="J8S10_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HAZ9630448.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVELAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(7878..9167)
                     /locus_tag="J8S10_001866"
     CDS             complement(7878..9167)
                     /locus_tag="J8S10_001866"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HAZ9630449.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(9321..10253)
                     /locus_tag="J8S10_001867"
     CDS             complement(9321..10253)
                     /locus_tag="J8S10_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630450.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLKEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(10410..11069)
                     /locus_tag="J8S10_001868"
     CDS             complement(10410..11069)
                     /locus_tag="J8S10_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HAZ9630451.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSLYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAVFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(11072..12097)
                     /gene="sppA"
                     /locus_tag="J8S10_001869"
     CDS             complement(11072..12097)
                     /gene="sppA"
                     /locus_tag="J8S10_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HAZ9630452.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELAPNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAIR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(12110..12400)
                     /locus_tag="J8S10_001870"
     CDS             complement(12110..12400)
                     /locus_tag="J8S10_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630453.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAQAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            12809..14614
                     /gene="glmS"
                     /locus_tag="J8S10_001871"
     CDS             12809..14614
                     /gene="glmS"
                     /locus_tag="J8S10_001871"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HAZ9630454.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDASDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(14686..16041)
                     /locus_tag="J8S10_001872"
     CDS             complement(14686..16041)
                     /locus_tag="J8S10_001872"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HAZ9630455.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(16065..17234)
                     /locus_tag="J8S10_001873"
     CDS             complement(16065..17234)
                     /locus_tag="J8S10_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630456.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(17231..18118)
                     /locus_tag="J8S10_001874"
     CDS             complement(17231..18118)
                     /locus_tag="J8S10_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HAZ9630457.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(18307..21999)
                     /gene="nifJ"
                     /locus_tag="J8S10_001875"
     CDS             complement(18307..21999)
                     /gene="nifJ"
                     /locus_tag="J8S10_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HAZ9630458.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIFPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPTMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLDNANPN
                     LAKALFEKTVHDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARRAARAERRKKMEQATKEKKEK"
     gene            22198..22719
                     /locus_tag="J8S10_001876"
     CDS             22198..22719
                     /locus_tag="J8S10_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HAZ9630459.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLACPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
BASE COUNT         6332 a         4939 c         4044 g         7420 t
ORIGIN      
        1 aaaacccagc ctcttctttt ttatttctat gcttctgcta ctgcaggagc ttttctcaat
       61 aaaccataaa tcacaccaga tacgactgct ccgatagcaa taaacaccaa atacatgacc
      121 gggtgactca gtaagaatac aacgaaaatc ccgccgtgag gagccagtaa tttgattccg
      181 aaagctccga ctaatccgcc agttaaagca gaaccaataa taaaacttgg aatggcacga
      241 atcgggtcag ctgctgcaaa tggaatcgat ccttccgtga caaacgatag tcccatcacg
      301 atgttcgtca aaccagcatc ttgatctgtt ttgctgaatt tattcttaaa caaacgtgta
      361 gcaacgaaaa ttgccaatgg aggtaccatt cctccagcca taacagaagc catcacgaca
      421 cttccgccag ttgcaacagt cgtagctaaa gttgctgtac caaacacata agcggctttg
      481 ttgattggac cgcctaaatc tgccgccatc attccagcta ataatgcacc aagtaaagca
      541 gcattcgaac cactcatact tgtcaagaaa ccgttcaatg catcattgat tgctttcata
      601 gggacattga ccagcaacat caagaaacca gtaatcagta agccaaacac tggataaaag
      661 aggatcgttt taattccatc caatgatttt ggtaagttct tgaataattt acgtaaaaat
      721 acgatgacat aaccagctaa gaatccacca atcagtgcac ctaagaatcc tgcaccgcct
      781 gtattagcta atgcaccagc agcaaatcca acgatcaaac cagggcggtc accgatactt
      841 gaagcaataa atcctgctaa taccggcagc atgaaaccaa atgcagcttg tccgatttgg
      901 ttgaaccagc tagcagcttg attgtaattc cctagatttg ataattgatc atgtggcacg
      961 ccaataaatt ggtcgatcat gaaagaaagc gcaatagcga ttcctccacc aataacgaaa
     1021 ggtaacatgt gtgatacgcc gttcatcaaa tctttgtaaa ttctttgtcc gatagtacca
     1081 tccgcatttc cttcttctga actgctttct tttccatcac catggaatac tggtgcagta
     1141 ccactaaggg ctagattgat caactcttct ggtttacgga taccatcact gacaggacga
     1201 ttgatcagtt cttttccgtc aaagcgattc atctctactt ttttgtctgc tgcaacgatt
     1261 acaccttctg cacgggcgat gtcttcagca gtcaatcggt ttttgattcc ttctgaaccg
     1321 ttcgtttcga ctttgatctc cacacccatt tctttcgctt ttttcttcaa agcatcttct
     1381 gccatgtaag tgtgagcgat ccctgttgga caagctgtaa cggcaacaac gaattttctt
     1441 tctggatgag cagaagcttc tgcagcttgt gtttcttgtt ctgctttttc ttctgcttct
     1501 ttttgctctt cagctgtttg gaacaagtct tggacttctt ctggtgtatt tgcttctttt
     1561 aattttccta cgaaatctgc atcaatcagc aatcgagata gtgctgctaa tgcttgcaaa
     1621 tgtgtgtcgt ttgcgccttc tggagctgcg atcatgaaaa acagataagt tggctgtccg
     1681 tctaaggctt cataatctac tcctttttgg ctttttgcga ataaaactgt tgcttcttta
     1741 actgcactgt ttttcgcgtg aggcatggcg attccatcac caagacctgt agaagtttgt
     1801 gcttcgcggg ctagaattcc ttctttatat gtttcgatat cggaaatccg gccggcatca
     1861 aacatttttt ggaccatttc atcgattgcg ccttttttat cagtcgcttg caaatccatg
     1921 atcatcgctt ctttgaccat taaatccttg atattcatga ttatcctcct tgaaactaat
     1981 caatttttgt gatttcaact tctggcagca actcatcaat caattcgcga gctgccaagt
     2041 catcagaaaa agctgttgcg cttccgcaag caactcccca tttaaaggct tcgattggat
     2101 ctttcgtacg gctgtaagcc ccaataaagc cagcaatcat tgaatcccct gcacctactg
     2161 aatttttcaa tgggcgaact aatacattcg ttttataagt tccttgttcc gtgaagagca
     2221 aagcaccgtc tccagccatt gagatcagca cattctgtgc cccttcagct agtaattttt
     2281 tcccatacgg aatgatttct tctacagatt ggaaggttgt gttgtaaagc tcagctaatt
     2341 cgtgattgtt tggtttgatc aacaacggtt tcttaacaag tgcatttttt aggtcatcac
     2401 ctgttgtatc aatcacgaaa tctgcacctt tttctcgaat gatatcaatc agttcttgat
     2461 aaaatccttt tcgcaggcta gctggcgcgc ttcctgacaa tacgacgata tctccttgtc
     2521 ctactgttcc taatgcttgc ttcaactcat cgatttcttc atctgaaata gatgggccta
     2581 agccattgat ctcagtttca gtgtctgatt ttagtttgat attgattctt gtatcttctt
     2641 ttacggttgt gaacaaagac tggatttgtt ctttttcaag ccacttcgaa ataaattcgc
     2701 cagtgaaccc tcctaaaaac cctagtgctg tagattgaga atcgatccgt ttcaaaatac
     2761 gggaaacatt gatccctttt cctccaggta acttgaagtc ttccttcatt cggttcaaat
     2821 cgcctagttt taacccatct acgcgtacga tataatcaat tgatggatta agtgttactg
     2881 tgtaaatcat tgtattgcct ccttaattgt tgtcttttca cggaattcat taacgaattc
     2941 taatggacaa cgctcggtta tgatcgtggc tgcttccaaa ggtgcaacag aggtgaagga
     3001 caactggttg aatttggtat gatcaatcaa tacaaatgtc tcttcggaat ttttcatggc
     3061 taaacgttta acagctgcct cttctggatc cggagtcgtg aatccttgtt caagatgggc
     3121 accgttcatt cccataaatg ctttattaaa atgaaaattt tttagttgtt ctatcgcatt
     3181 agatcctaaa acagcattag ttgccagctt tatcgttcca cctaaaataa tggtagcaag
     3241 ctccaaatca actaaatttg ccgcatgttg aacggaattt gtcactactg tgatctgttt
     3301 tccttgcaga aaaggaatca tttctaacgt agtagagcca gcgtctaaat aaatgacatc
     3361 ttcgtcatta atggtttcag ctgccgattt ggcgatttgc tgtttttcgt gaacgttttt
     3421 gagtgatttt tcactcatat tctgctcaaa attcaataat tgctctttct tagctccgcc
     3481 atgaactctt tctagaaacc cactattctc cagctcttgt aaatcacgtc ttatcgttga
     3541 ttcagaagca ttcaaaaggt ttacaagatc ttgtgatttc acgattttct gctgttcaag
     3601 caagtctagg attttttgtc tgcgttcctc tgtaagcatt ttcacgatca cctcaataca
     3661 aataatagca tatttttttt ctactagcaa tataaatcag tcaaaaacgt tcataaaaat
     3721 tataaatcag tcaaaaaaaa aataaaaaac cagtcagaaa gactggtttt ttattttttt
     3781 gtctatcatc aagccgtttt atcgtttttt attttcgctt cttgtttttt tcatataaac
     3841 agaagcaggt tttctttcct tatgaagaag ataataataa agtcccatcc cgccaaacat
     3901 gaccaaaaaa ccgatgactg atcgaatagg aaaattagga acaaaaaaga gacagacgga
     3961 taataatgat gccggaacca ttattcgata atagagttgt ttatccattt tcttcacctc
     4021 atattttttg taaagtaatc aattgttcta attctcggta atctaaaaat tgcacacgca
     4081 gatgctgctc acctttcttg acatcgaatt ggatacttcg ccgctttttc tttattcgtt
     4141 tgaaggtaac atcagagagt ctatgtttga tttcctttaa cggtaattct gacagggatt
     4201 ctgaaggaac atagattctt aaggataaaa gatactcttg atatttttca tctgttacct
     4261 ctacttctag atattcccta atataataac aataagcttc gattccatta tccaaagcaa
     4321 cagtcggatc gataacttta tagcacatca tgcgtgatcg attctcgtca acccaaggaa
     4381 aatacgcctg agcatttagt gttccgcgaa cacgcctttc tttataatct ccttgttgga
     4441 tatcataact ttttgttaca aaaaatgaag cattcttttt aggaacaggt tgcatttgtg
     4501 cattctgata ctggacagat tggatcgtat ggtcagtgta aatgtattca acgaatggcg
     4561 gtttcaataa accgacacca ttgtcccaag caagatgatc aaacccaagc tggtccctaa
     4621 aataggattg aaacatttga ttgtttggct tttgccagtt aaaggggtct cgataaagct
     4681 ggatacatat gacttcgttt tctaattcct tcactttttc tacttgttgg atgtcgagaa
     4741 aaatcggttt agggatgatt tgatgataat agcgactata atacatttcc caacacgaag
     4801 tgaaacataa accttggtaa aaaagatcgt atcctggaaa ttggttgcaa tcgactacta
     4861 cttccccgtt ttgttgtttc attttaggta aatgttcgat ttcatccttt ttctcaaaca
     4921 atagccgttg agagatctgt tttgtattgt gatagataaa ctcgctataa gctcgcatat
     4981 aggcgaacac cccatgagca atcatttttt tctgaatgaa gtctcgaatc aaaaattgct
     5041 tttctttgaa aacagagata gacaatacat tttttatcaa taattgatta tcttccaagc
     5101 gaaaactaca ttcgttctcg tcatttccta caactaacca actttcgtct cttaccgatg
     5161 ctagcattat tttttcttga agctttcgaa gatcatacgg atccgcttgt tgtgtgaaag
     5221 agcggataaa tgttggctgg atcaacagac gtgtcaaaat agcccaatcg cttatttcct
     5281 gtttttttct tcttcattta agtctgtgag ctggatagtc atcaataatt tatcttcgcc
     5341 aatcattttc tcacctcttt caaatctttt tataatttaa ttataaccaa tgataaagaa
     5401 aaactaaaac tttatgtctt agaaaccaat ttggacgatt acatgataga ctaagtaaaa
     5461 agaaacaaag aggtgtttac aatggggttg aaatttgaac gtacagataa tttagataaa
     5521 cttttcgaat catttgctgt cgatccggaa aaaacagttg caccaaaaga agagatcgat
     5581 cgatttctaa aaccacagcc acaaaatgaa aagaaaaaag acaagaaaca aaagtaagtt
     5641 aagctcaaaa aaagacttac cagccaaact tttatgaaag agtttgactg gtaagtcttt
     5701 tttattcttt ttatgattca attgcttgtt cgattgctgc ccacgcttct tcttttccct
     5761 gttttgtaac ggaagaaaag agaataaacg tgtcattgcg atcaaaatcc aacgcttttt
     5821 tgatttcgct ctcatgcttg ttccatttac cacgagggat cttatctgcc ttagtggcaa
     5881 caacaattac agggatatca taatacttca aaaattgata catctggata tcttcttgag
     5941 aaggcttatg acgcaaatct actaaagaaa cgaccgcacg tagctggtct ctagtcgtta
     6001 aatatgtctc gatcatcttt ccccattttg ctcgctcagt tttggatact tttgcatacc
     6061 catatcccgg aacatcgaca aaatgtaatg cgttctcgat caaataaaaa ttcaatgtct
     6121 gggtctttcc tggcttaccg gaagtacggg ctaaattctt tcgatcaatc aatgtgttga
     6181 taaaagaaga tttccctaca tttgatcgtc ctgccagagc tatttctggc aattgtgtat
     6241 ctggatattg ttttggtgcc actgcactta tgataatttc agcttgatgg actttcatgg
     6301 tctctctcct taacaaggtg atgaataaag caagcggctg tcgcaaaagc caaaatgact
     6361 tttacggcag cctcttttca tcaacccgct tttttctctg aatctttata gattactgtt
     6421 ggctcaccag acaattcagc tgcttctttt gtgataatca ctttttcgat gttttcattt
     6481 gaagggatat caaacatcac atccatcatg atttcttcaa tgatggaacg aagtcctcga
     6541 gcaccggtat tgcgttcgat tgcttttttc gcaatggctc tcaacgcttc aggttcgaat
     6601 tcaagttcgg tattatctag agaaagaagt ttttgatatt gtttgactag cgcatttttc
     6661 ggctcagtca agatccgtac cagatcatct gttgtcaatt tctctaaagc tgccataaca
     6721 ggtaatcgtc cgataaactc agggatcaat ccgaatttta gtaaatcttc aggaatgata
     6781 tgctgcatga cactttcgtc ttcagaaagt ttttggtttt gtgtaccaaa tccaatcgtc
     6841 ttttcgccca tacgattctt cacaatcgtt tcgatgccat caaatgcacc acctacgatg
     6901 aacaatatgt tcgtcgtatc aatctgaata aattcttgat gtggatgttt acgtccgccc
     6961 tgaggtggca cacttgcaac agttccttct agaattttca gcaaggcttg ttggacacct
     7021 tcgccggaaa cgtcacgagt aatagataca ttttcgcttt tacgcgcaat tttatcgatc
     7081 tcatcaatat agatgatccc tttttctgca agttccacat tgtaatcagc agattgaagc
     7141 aatttaagca aaatgttttc tacatcttcc cccacataac cagcttctgt caaacttgtc
     7201 gcatctgcga ttgcaaaagg tacattcaat gtttttgcta atgtttgtgc taaaaatgtt
     7261 ttaccagacc ctgtaggtcc gatcaagcag atattgcttt tttgcagttc aacatcatct
     7321 gtgttttctt gtgcttgctg attgacacgt ttatagtgat tgtatacggc aacagctaac
     7381 gagcgttttg cgcgatcttg tccaatcacg tagttattca atacttcaag aatttctagt
     7441 ggtttaggga cttcagtgaa ttcgcgtaca gcttcttcat aaaattcttc atcaatgatt
     7501 tctttacata ggtcgataca ttcattacag atgtagaccc ctggaccagc tacgatcttt
     7561 ttcacttctt cttgggtttt cccgcaaaaa gaacagcgta cggtctcatt gctacttgga
     7621 ttgtcataca tggtcttcac cccttaactt gcaaaaagta tgcaagaaac tatcaaagac
     7681 tttacagtct tttactatca taacatagtt tagtaaaaag aaaaagtgtt taacaaagga
     7741 tcaactgacc tatacctttg cattttttac tcttaacaaa aaataaggaa ctgtgacaaa
     7801 atcgtgtcac agtcccttat ttcgaataaa caattttcta gaagtagctt cttcagaaat
     7861 gatttattac ttgatttcta ttctttcgct tctgtcgctg tacctgtgat caattcgatt
     7921 gcttttttca ttgtcacatc atgttccagc atatcttctg tcaacacgcg tttgatttgt
     7981 tcgattggca tgttgtatgt ttctgataat tcttggattt ctgcattgat ttcttcttct
     8041 gttgcttgaa gattttcagc agctgcaatt gcttcgatca caagatttgt tcttgtgcgc
     8101 atttctgctt caccttcgaa ttgtttatgc aagtcttctt ctgtagaacc agttaattga
     8161 tagtacattt caggagagat accttgacgt tgcatgttgt tcaagaattc gtccattgaa
     8221 cgatgtactt catcatgaac catcacgtgt ggcaattcaa cgatttctgc gttttcaaca
     8281 gccatacgga tcgctgcttc atcttttgca tcgtccgctg ctttttcttt tgtttctact
     8341 aattctttgc gatatttttc tttcaattcg tctaatgttg atacttcgtc atcaacatct
     8401 tttgcgaatt cgtcatctaa ttcaggcact tcttttgctt ttacttcatg gattgtcact
     8461 ttgaagactg cttcttttcc agcaagatct tctgcttgat aatcttctgg gaaagttaca
     8521 tttacatcta gactttcacc tgatttatga ccaactaatt gatcttcaaa acctggaatg
     8581 aatgagcctg aacctaattc aagtgagtaa ttttcgcctt ttccgccatc aaacgcttcg
     8641 ccatctacaa agccttcgaa gtcgattact actgtatcgc cattttcagc tgcagcatct
     8701 tctttgataa ctaattcagc ttgtgcttct tgttcacgtt tgatacgtgc atccacgtca
     8761 gcatctgtta cttcacggtc ttgtttttca acaactagat ctttatattg tcctaatttt
     8821 acttctggtt tcactgttac ttcagcagtg attacccagt cttgaccttt ttccatgctt
     8881 tcaacatcga tttttggttg agaaacagga tcgatgccag cttctttgac agcagcttca
     8941 taagcttctg gtaatacagc attcaatgca tcttcatata aagcttcttc accgtacata
     9001 cggttgaata cttgacgaga aactttccct ttacggaatc caggtacgtt caagcttttt
     9061 ttcactttat taaacgcagt tgttaatcct ttttggattt cgtcttgcgc aatcgtaaat
     9121 tttaaaacac catcattcgt gccttttttt tcaaatgttg cagtcattta attccctccg
     9181 agtttagaaa ttcattttat acatcaaaaa cgtttcatgc atacctttaa atagtacact
     9241 aaccctttca aattgtaaac atattgaatg gatagaatcc ttgtttttca taacattttt
     9301 atctttttca ctgataaaat ctaatggaag aagatcattt gctgcaaaat tttttctctt
     9361 ttttttaaaa aatcttgttt ttcatcttct gtaccttcat acatcgtttt tcctgtacac
     9421 gcctctacag tcagttgaaa ccagcgcttc gggtcttcga tgtatgtatc atagacagga
     9481 taaacaattg cagattgcaa cgtgaattct tcttttaaca cggaactaag cagcgcatct
     9541 tcattcccgt aacgatctga aaatacacat aattgctggt aacttgcctg ctgctgcggc
     9601 tttggcagat cttttggtat gactttgact aacttttctt caatcgtcaa atagaaaaca
     9661 ggatggcatt cgttcaattg cctaagtgtc tccagtaatt ttgcccttgc taaaatatgg
     9721 acctctggcg atacaataag tttactcgct gtttggataa actcatgata aggaagctgt
     9781 tcgatctcat caatagacgc aagctgacgt gcaggttcca acgaaggaag ttcctccgat
     9841 ttattgtgga gtgccttgat cttctgcctc tccatttgtc cggataattc ttctgcaaat
     9901 tggatttttt caatgacccg ctgctcgaaa gcttcataaa aatctgtact tgctatcaat
     9961 tttctagcat ataaaaaatc ttgtgtactg attaacaagt caaaataaaa ttcagcaaac
    10021 tcctcatttt gaagatactg tttttcatgc aagagtgctt gcttcaatgc ttcttttttc
    10081 tcgtccaact cgtaaagaca aaaaacaagc aggctattag cctcaaagct ttctttcaac
    10141 tcgtaagctc gttgaaataa ttcttttgcc tgctgatatt gctggtttgc tagtgcttgt
    10201 tgtgccactc gcattaaatt ctcatatttt tctggaaaat caatcggctt cacgcagtgt
    10261 cctcctcttg ctcatattca gctcatgttc aatagtagca aaacaaaaaa agcatgacaa
    10321 ttaaaaataa ctgaagcacc ctctaaaagc tagattttag atctgacttt tagaaggtgc
    10381 tttcaactgt tactgctttt tattgctcat cagctgttga cttcctggtt gaacgctttg
    10441 atcagattga tcgtaacaac acttgtatta gtgaaaaaat cgcccagatg ttgctttttc
    10501 tgattaaaga ctgctggaag ataccctaac atcagcaaag gaaattttag aatgaaccgg
    10561 caagcacctt ctctaactaa aacggttgac cagctaagtt cttcttcatc aaagctgatg
    10621 actcgaatac caaagatcat tttcccaatc gtttggccat gattgaattt cgtcaataaa
    10681 ataaaatacg ctagataaat aagtaaggct gtgaatccgt agagactcag ataagaatct
    10741 gaaaaattaa gccaacctag atttttggca ataccaagtg ttaaacgcgt aatagctccg
    10801 atacacaaaa gatcgaccaa gaaggcaaac attcggataa aaaaacctgc atagaaatac
    10861 ttaggaaaat catttgcttt tggcggttca tttcttgtgt ccgtatactt tttccattta
    10921 cgttgtttct ttttgatttc ttcgggcgtc aaaggctctc tttcaaaaga gctcagtacc
    10981 ttttgggaaa agttggagtc aggtcctaca gcaggctgct gttgcttatc tttttcttgt
    11041 tccttatttt catttgaaag ctctgacatg cttactcacc tccgtaataa tacattgctt
    11101 ttggtgattc cgctgtccct agattctcaa gaacggataa gatctgacta gtctcagaag
    11161 gcttcaatcc ctggaattct gctagtttac ttcctaacca tgtactagca aacccagatg
    11221 gcgtggaaga atattctact agttccgcat cttcaagctg ttgttccttt cgtatagctt
    11281 ttaaagcatc ttcaggaaat cccaattcat cgactaaacc tacttctttt gcttggacac
    11341 catcataaat ccttccatca gcaatttttt tgacttcttc ttcagattta ttccgtccct
    11401 cgctgacgat tgctacaaaa cgactatatg cgctgtcgat atatgcttga agcaccgctt
    11461 cttcttcttt tgtctctggt cgcgttcctg aacccatatc tttcaacgct ccgcttttaa
    11521 ctgttgtatc ttccacaccc agtttttcta gaagtcctga ataattcaat cctgacatga
    11581 tcacaccaat tgagccggtc actgtttctt ctgttgcaaa gattttatct gcttgagcag
    11641 aaatatagta gccaccgcta gctgccatgt ttttcatgct gacatacatt gggatatcat
    11701 gttctttacg aatcgtatcc aatttcttag cgatttccgc actttcgtag acaccgccac
    11761 caggagaatt tacttctaaa aagatacctt tgactgttgg atcttcttca atcgccttca
    11821 gttgttccat aaaattttta tgattgtaac cttcagaagc aaataaacct gaagaccctc
    11881 ccgcagcaat cgttccatct actgataatt ttacgatttt ttgcgtactg tctccctctt
    11941 ccaacacatt tggagctagt tcttcatccc catataacca actgttcaat ccctcaattt
    12001 gatcgttttc ctgaggctta gtcaaactag ctgaaactaa cgaaaccaca aataatcctg
    12061 cagcaatcag aactgctgcc caacgtcttt tattcattct ttctcctttc taatacaagt
    12121 tttttatgac gatcacagtt tctgactgct cagaagtgtc gaaccgctct gctttttctt
    12181 cccgcgcata cccggaaaac gactcttttg ttaattcatc ttctaccgta aactcacgag
    12241 cttgagcaac ttccaaggca tcaggtgcga tttcttggat gctatcccag ccagtatcta
    12301 aaaatatttt cgtatcatct gatacaccag ctgatgcttc gaatttggac aattgttttt
    12361 ttaacattcc cagtgtcatg atctcaattt ttgaatccat ttttactcct cctctatccg
    12421 attactttct attgtaccga actcctgaaa aagatgatag ataaaaaccc attatttttt
    12481 gacataaaaa ggacatttga caaagaattt gatatatacc aatttatttt ttattctttt
    12541 tttgttgaca agaacattcg caaaaggtta tgattttaaa tgtttccaga taaaaaacaa
    12601 aaaggaggat agttatacct tttaggatag cgccaggtct gtgtaaacag atgacgagga
    12661 gagggtttat cgaaagattc ggcggatggc cctagggact gcactctaca gaaaatccac
    12721 aaaaaatgtc tgcaaagata aaacaaaagg attttcctgc agctggaagc attcatacga
    12781 attcattata gaaagtagga tgttttttat gtgcggaatt gttggaatga ttggattaaa
    12841 aaatgtaaca ccaggattga ttgacggtct agaaaaatta gaataccgtg gttatgattc
    12901 agctggtatc tttgtctcag atggcacaac tgattatctg gtcaaagcac aaggcagaat
    12961 tcaaaatttg aaaaacaaaa taaatattga tactacagga aatataggta ttggtcatac
    13021 acgatgggca actcacgggc aaccttctga agaaaacgcc catccacata cttcccaaag
    13081 tggacgcttc gtgctcgttc acaacggcgt aatcgaaaac tttgaagaac ttaaaattgc
    13141 ttatttagca aatgaccact ttattggtga gaccgatact gagattatcg ctcatctaat
    13201 tgaaactttc gcgaaggata ctacaacgca agaggcgttt ttaaaagctt tgcgggtcat
    13261 caaaggttct tacgctttcg ctttgattga tcggacagca cctgatgtta tttacgtcgc
    13321 taaaaataaa agtccactat taatcggact cggcgatgga ttcaatgtga ttgccagcga
    13381 tgcaatggct atgcttgctc atacgaagga attcgttgag attgaagatg aagagatggt
    13441 taccgtcaca tcagaaaaag ttattattca aaattttgca ggtgacatcg tagaacgttc
    13501 ttcattcgaa gcacaagtag atgcttcaga tatcgagaaa ggtacctatc ctttttatat
    13561 gctgaaagaa atcgacgaac agcctattat catgcgtcgt atcgctcaaa aatacgtaac
    13621 agaagacaat cgtgtctctc ttgatcaaaa gctggtcgat acattgtctg atagcgatcg
    13681 aatctatatc gttgcttgcg gaactagtta ccatgcgggg ttagcaggta aacagacttt
    13741 ggaaaaattg acacagattc ctgttgaggt tcatttagcc agtgaatttg gctataacac
    13801 acctcttctt tcaaaaaaac cattctttat tttcttgagt caaagtggcg aaacagcaga
    13861 cagccgccaa gtgctggtaa aaatcaaccg tctcggctac ccttcactta cgattacaaa
    13921 tgttgctggt tctactcttt cgcgggaagc atcctttaca ctgctattgc atgctggacc
    13981 cgaaatcgca gtagcatcaa cgaaagctta tactgcacaa atagctgtac taactttatt
    14041 agccaaagct atcggtgata aaaaagaatt tgaaacttct cttgtattcg atatcactca
    14101 tgaattgagt ttagttgcta atgcgatgga atcggtcatc gcccaaaaag attatttaga
    14161 agagttggca gaagtatatc tcagcgatac aagaaatgcc ttttacattg gacgtggtgc
    14221 tgactacaac gtttctcttg aagctgcttt gaaattgaaa gaaatcagtt atatccaggc
    14281 agaaggtttt gccgctggcg aattgaaaca tggaacgatt gctttgatcg aagaaggaac
    14341 accagtgatc ggaatcatca gtgaagaagt gactggtgcg catactcgag gaaacctgaa
    14401 agaagtcgaa agccgtggcg ctaaaacact agttattgtc tcagagggat tagaaaagga
    14461 aagtgaccag ctggtgctac caactgtcca cccttatcta actactctaa ccacagtcgt
    14521 accgactcaa ttacttgcat attacgcaac gctattacgg ggattcgacg ttgacaaacc
    14581 acgtaattta gcgaaatcag tgacagtaga ataataaaag aacaaggacc agtgtcagac
    14641 atctgacact ggtccttgtt cttttatttt ttatgaaaat atctcttaat ccagtccgat
    14701 ttcttctttg actactgccg cgattttatc gacatagtaa ttaactttct catcagtagg
    14761 cgcttctgcc atcactcgaa gtaatggttc tgtaccggaa ggacgaacta ggattcttcc
    14821 ttctgatccc atttcagctt ctgcctcttc aatcactttt ttgattgccg gaacatccat
    14881 cgcaccgttt ttatcactta cgcggatatt cactaatttt tgcggataga ttgttacctc
    14941 tgctgcaagc tctgataatt tcttacctgt ctgtttcatg atattcagta actgaattcc
    15001 tgaaagcatc ccatctccag ttgtgttaaa atctaagaaa atcatgtgcc cagactgctc
    15061 gccgccaaag ttataatcgt ttttgcgcat ttcttctaca acgtaacgat caccaacttg
    15121 tgtaacgaca tctttcaaac cgattccttc caccgctttg tggaatccta agttactcat
    15181 gacagtcgta acgatcgtat cttttttcaa tcgatttttt tctgccaagt atttagcaca
    15241 gataaacatg attttatcac cgtcgacaat gtttccaagt tcatccaccg caataatacg
    15301 atcgccatcg ccatcgaaag ctagtccagc atctgctcct ttttcaacga ccatctcagc
    15361 taaacgttct ggatgggtag agcctacgcc gtcattgata tttaacccgt ctggatttgt
    15421 gcccattgta taaaaatctg tttcaagatc ggcaaacaaa cgattaacac ttgttgaagt
    15481 tgctccgttt gctgcatcga cacaaatggt caaaccggaa aggtcaccgt tgatcgtttg
    15541 tacaaggaat tgagaatatt tcaataagcc ttctggaaat tcttctacag ttcccaatcc
    15601 ttcagctgat ggacgaggca attcatccac ttcagcatct aataatgctt caatttctag
    15661 ctcttggtca tctactagtt taaaaccatc tgcaccgaaa aatttgattc cattatcttg
    15721 tgctggatta tgagaagcag aaatcatgac ccctgcgctt gctttttgca aacgtgtcag
    15781 ataagcaaca cctggtgtag agatcacacc tagctggaac acttcgatac ccaccgataa
    15841 aagtcctgaa atcagcgctt cttctaacat ttgacctgag attcttgtat cccgccctac
    15901 taacacgcgt gggcgttttc cttcttcttc atgctggctt aggacataac ctccgcaccg
    15961 tcccagctta aatgcaagtt ctggcgtaag ttccttgttg gcttcaccgc gtacgccgtc
    16021 tgttccaaaa tatttaccca tagttgtaaa attactcctt taacttaatt ttctgaggaa
    16081 tttgttctgc tcatttgtgt tgattcgctt gtttctgatg tttcttctgt acttgtggtc
    16141 gagctgcttg tcccagattc cgaactggaa gaaatggttg ttgtcgatgg ttccgttcct
    16201 gaatcagcag atgaaatact tctactcgta cttgtatttt cttgtgtccg actgctcgtc
    16261 gaagcagagc tactgcttga cgtttgcaac acgggtgtaa tctccacact aactgattcg
    16321 ggcttgatac ttaacccctc ttctactggt atttcaattt tacgagttgt tcgatgattg
    16381 atacctgaga cattgatcgg tacagcaata ctgtcaccga tcgatgcaag caaatcgcta
    16441 gagccgctta cttctgcttc cagttttgaa aaactgaaat catagctttc taccccggca
    16501 gctggtgttc cttgctgtat cccataaagt cgtaccgact tgcttggctt gatcgaatca
    16561 gctctcactg ttacttgcac tggatcagag acgatactta atacttcccc tgctgcattc
    16621 agcgcctgta ttgggacctc actattaatc ccatcatctg tgaccatcga agcgtccaca
    16681 tcagctacta ctcgtttgat ttctgccaat gttttgtcac ctgtagtgat agagactttt
    16741 ttaggactaa cggaagtatc atcaagttca tatccagatg gtgtgaacgt tgaaggaatc
    16801 aacgtttcca catcgaaatc ttttattacc tttttctcaa ccgttactgt aatagtcgat
    16861 ggttcgatct ttgctgtgac agcactgctc aaattttgaa tttttagcgg aacttcatgt
    16921 gttccttcgc ccagcttagt gatatctgct gtgacgcgga acatccgtgt atcttcgttt
    16981 gcctctgcat tcaactgaac tcggtttgca ctggaaagtt tgacagtcac tgcattttca
    17041 tatccatgga tatagtagcg ctttgaatca taagaaatct tgatcggcac ccccgtaact
    17101 gtttgattat acgcttcatt tccagaaagc gtatttggaa cggactggcc atttgcattg
    17161 aagtacagcg caatactgaa cagcaatgca ataaaactgt aaagaatgct tgtccgtttc
    17221 tcttttgaga tcatttgcga tcccctccct tagtcatacc gtctaggaaa gattgaatca
    17281 cgtttttctt gttttttgtt ttctcttcag caattagttc tctacgcaag attgccaaat
    17341 attcttgctg ggataagcca gccatcagtt cattatctaa cgtgatgctg acgtccccgg
    17401 tttcttcaga gacaacgatg gtaatcgcgt cactgacttc gcttataccg acagctgccc
    17461 ggtgtcgagt cccgaattct ttagggatca acatactttc tgatagagga agataggcgc
    17521 ttgctactgc gatctttcct tcttttacaa taactgcacc gtcatgcagc ggtgtattag
    17581 gaataaagat attgatcagc agctccccag tgatatctgc atctaaagca atccctgtct
    17641 caatatactc atctaatcca gtatgacgtt cgatagtgat caacgcaccg atttttcgct
    17701 tggacatata ttggatggct ttgtcaaaag acaagatcat cttctcatct tcctgctgtt
    17761 cgctttttga ttgtttgaaa agcgaactgc gtccaagatg ttccagtcct ctccggattt
    17821 ccggctgaaa aatcacgata gcagctatca ccccgtacgt aatgacttgg ttcatcagcc
    17881 aagacaaggt gtgcagacca atgatttccg ctacgattcg gataacaata aaaatagcta
    17941 cacctttcag aagctgaatc gcttttgtgc ctcgcagcag ttggatcagt ttgtatacaa
    18001 gataccagac aaccagaata tcaagtatgt tcaccaaaaa attcagagag aacaagtcac
    18061 cggaaaacat ttgctgccaa tagtccaaat taaaaagttc cccgatttga aatgacataa
    18121 aaagcctctc ttctcttttg agatttcctc tctagtatat catatgtttt aattttagag
    18181 gctgatatgc tcgtattttt cttgagaaaa acgcataatt ttcaagaaaa ttgcaagtat
    18241 gcgttttatt tttctctgca ataaatattt ttaaacttca gagaattatt cattatattt
    18301 tttctgttat ttttcctttt tttcttttgt agcttgttcc atttttttac gtcgttctgc
    18361 tctggcagct cttctagcag ctcttctttc ttctgcttca aggtccgtcg ttttttcttt
    18421 tctagtctta acgggtacat cgatagattc ctctggttca agtcgtttct tgattttttc
    18481 taattctccc gtcagtgcag catagttgta aaaacgtgtt ttagcgtcgt ggacagtctt
    18541 ttcaaataaa gcttttgcaa gatttggatt tgcgttatct agcgaggaaa agcgaacttg
    18601 tttcctcatg aaatcaggca tagcagagaa atcaggtttt ttgtagtcca aagtcattgg
    18661 gttcttgttt ttttcgacca ttgtagggtt atatcgatat aatgaccaat aaccagaaga
    18721 aacagcttct tttgcttctt taagcgattc tttcattccg ccaagcaagc catgtgtgat
    18781 acaaggcgta taggcaataa tcagagaagg accaggatac ttttctgctt cttcaaatgc
    18841 cttgatcgtt tgcatttgat tggcacctga agcaatttgc gccacataaa catttccata
    18901 tgtcatcgcc atcattccta gatctttctt tgaagcatac tttccactag ccgaaaattt
    18961 agcgattgcc gaagctggtg ttgcttttga ggtttgaccg ccagtattgg aatagacttc
    19021 gttatccaaa acaaggatat tcacgtctgc tccgctggca agtacatgat cgatcccgcc
    19081 aaaaccaatg tcgtaagccc atccgtctcc accaatcatc cattggctgt tttttacgaa
    19141 tagatccttt ctcttgtata tatcctccag ttcagggaaa attgatcgtt cgctttcgat
    19201 cgcagcttgc agttttgctg ctctttgctg cgttccttca ctctcaaaca tgtgtactaa
    19261 ccagtcttcc atcaattctc gtagttcttc tgatactttt ggcaatactt ctttgattga
    19321 acttgccaaa gcctcgcgac gagtctgtgc cgctagaagc ataccataac caaattcagc
    19381 attatcttcc aataaagaat ttgaccatgc aggcccttga ccacattcat tggtcgtata
    19441 aggagaagca ggagaagcac cgccccaaat agaagaacag cctgtcgcat tcgcgatcat
    19501 cattcgatca ccgaacattt gtgtcaataa ttttacataa ggtgtttcgc cacagcctga
    19561 gcaagcgccc gagaattcaa gaagcggttg attgaattgt gtagacaaga cagtattctt
    19621 tcctttgact ggatttgctt tttgtcttaa tgtcattgca aaagcccaat tcacagcttg
    19681 ttctttctgt tcttcataag gcttcatcac taaagctttt tcttttgcgg gacaagcctc
    19741 tacacacaga ccacaacctg tacagtcttc cactgaaact tggatacggt attttacgcc
    19801 gtctgcgcct cgcatttctc tcacgataaa tccttctggc gcttcttcca tttcctcttc
    19861 atctgctaaa aatggacgga tggcagcatg aggacaaaca aaggcacatt cattacacat
    19921 cgtacagcga tcactaatcc actcaggtac ttctaaagcg acgccccgct tttccataga
    19981 agccgttcct aaaggcattt cgccagttgt cattccattt gctacaagtg taccaacaga
    20041 gagttgattt ccttcctgtg cattcactgg ttcaagtatt tcttgtatat aaccagtgtt
    20101 ccttttattg attttttcag gcatctccaa cgttctccaa tggtctggga tcgcgacttg
    20161 atgaagcagt tcggtcgtcc gatcgattgc ttgtatgttt ttttctacga tagccattga
    20221 tttatgtcca tagcttttca gggcttcttc ttttagcagc ggaagcacct catcaaaagg
    20281 aatgatgtca gctaatttaa aaaaagccgt ttccattgcc gtattgatcc ggcgtcccaa
    20341 accgacttct tgggccaatc tcatggcatt gatcgtatag aatctaatgt tattttcagc
    20401 caagtaacgt tttaatttta agggcagatg cgtttctaat tgttcgtcgc tccaaagagt
    20461 attcaataaa aaaatgccac ctggcttcaa tcctttgacc aagtcatagc tatgcaggta
    20521 agctggtgtg tgacaggcaa caaggtccgc atgctcgaca agatacgctg aacgtatcgg
    20581 cgtatctcca aaacgaagat gagagacagt cagaccgcca gattttttcg aatcataata
    20641 aaaatagcct tgcgcatatt tatcggtgtg atctccaata atcttgatag ctgatttatt
    20701 tgctccaact gttccgtcag atccaaatcc ccaaaacttg gcctggaatg tttgcggttc
    20761 tgtcaaatcc agactttcct ttggttccaa agattgataa gtcacatcat ccacgatccc
    20821 tatggtaaac cgttttttgc gtatgcttgg gtcttttttc aattcatcaa aaactgctga
    20881 gatttggtcg ggagtcacat ctttagaccc caatccgtag cgaccaccaa taacagccgg
    20941 gcgaagttca gaatcatata acgcactttg aacgtctaat aagagaggtt ctccacctgc
    21001 ccctggttct ttacttcgat caagaacagc aattgttttt actgtatgag gcaacttttg
    21061 cacgaatgtt tccactggaa aaggacgata aagatggata ttcaaaaaac ctgttttccg
    21121 tccgtttgca ttcaagtaat caatcgtttg ttcaatcgtc tgtgcaactg atcccataga
    21181 aacaatgact tcttccgcat cgtctgctcc gtaataagtc accaagtcat aagaagttcc
    21241 tcgtaatcgg ttgatctctt tcatatattt ttgaacgatt tcaggtaatt tatcataata
    21301 ggggttgatc gtttcccgtt gttgaaaatg gatgtctgga ttctggttcg taccactaac
    21361 agtcggatga ttgggattca tccctcgttt acgaaatgaa gctaatttct cctgattgat
    21421 cagaggagct aattcttcat attccaaaac ttcgattttt tgaatctcgt gactcgtacg
    21481 gaatccatca aagaaattca aaaaagggac ttctccttca atagaagcaa gatgggcaac
    21541 aggtgctaaa tccatcactt cttgtacact gctttcagct aacatagcaa atcctgtttg
    21601 tcttgcagcc atcacgtctc cgtgatctcc gaaaatattc aacgcatttg tcgtcactgc
    21661 ccgactagca acgtggaaaa cacttggcag tagttcccca gcaatcttgt acatattcgg
    21721 tatcatcaaa agcagccctt gtgaagcggt atatgtagtt gtcagtgcac cagttttcaa
    21781 tgatccatgg accacaccag ctgctcctgc ttcggattgc atttctacta cttttactgg
    21841 ttgaccgaat acgttttctt ttcctgctgc tgaccattga tctactaatt cagccatggt
    21901 cgaactgggt gttattggat atattgcagc aatctcggta aatgcataag aaatatatgc
    21961 ggctgccgta ttgccatcca ttgttttcat ttttcgcatg attcatcatc cttgttcata
    22021 ttctctctta ttatctgttc cattataacg taaaacatgc catttttttc ttttatttat
    22081 aaaaatattt tacatgtatc tatttgaatt ggtcatctaa tttttagaca aacagtctaa
    22141 atcgttgcct ttttttgtca gacatgtata aactataagc gaaagaggtg ttttaacatg
    22201 gatatatcag tgattgatgc aacgaaaaca aatacacaaa aaggaatcct ttatggttca
    22261 tcgaatgctc ctaaaaaaat ggtcgaattc atcaacttag cttgtccgta ttgccgacaa
    22321 tggtttgaag aatcttatga gctattagaa gaagcagtcc aaagcgggca attgcagcga
    22381 gtgatcaaat tgttcgataa agaaaaagaa agcttacagc gagggaacgt gatgcaccgg
    22441 tatctcacaa tcagcgatgg ccaaaaagcg atcaaagaga tcaaacaaat attcgatact
    22501 caagacgagt ggaaacatct ttctctccaa gaagtagcgg attttgcagt agataaacta
    22561 aagctgacag aacaaaaaga cgaacagctg agccaagctg tcatcaacga agctgagcaa
    22621 gcacatattc gatttgttcc aactgtcatc ttgggtaaag aaatctttga tgaatctatt
    22681 tcaatagagg aattaaaaga attgatccaa acaaaataaa aaaataagga gcgtg
//
LOCUS       DADQDV010000047        22575 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.047, whole genome shotgun sequence.
ACCESSION   DADQDV010000047 DADQDV010000000
VERSION     DADQDV010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22575
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.047"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            3..650
                     /locus_tag="J8S10_001877"
     CDS             3..650
                     /locus_tag="J8S10_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysis protein"
                     /protein_id="HAZ9630460.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            734..1678
                     /locus_tag="J8S10_001878"
     CDS             734..1678
                     /locus_tag="J8S10_001878"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HAZ9630461.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            1813..3264
                     /locus_tag="J8S10_001879"
     CDS             1813..3264
                     /locus_tag="J8S10_001879"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HAZ9630462.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            3285..4121
                     /locus_tag="J8S10_001880"
     CDS             3285..4121
                     /locus_tag="J8S10_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HAZ9630463.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            4121..4780
                     /locus_tag="J8S10_001881"
     CDS             4121..4780
                     /locus_tag="J8S10_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAZ9630464.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            4906..5595
                     /locus_tag="J8S10_001882"
     CDS             4906..5595
                     /locus_tag="J8S10_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630465.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            5601..6557
                     /locus_tag="J8S10_001883"
     CDS             5601..6557
                     /locus_tag="J8S10_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HAZ9630466.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHRIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            6601..7113
                     /locus_tag="J8S10_001884"
     CDS             6601..7113
                     /locus_tag="J8S10_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAZ9630467.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(7369..7917)
                     /locus_tag="J8S10_001885"
     CDS             complement(7369..7917)
                     /locus_tag="J8S10_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAZ9630468.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(8006..9187)
                     /locus_tag="J8S10_001886"
     CDS             complement(8006..9187)
                     /locus_tag="J8S10_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HAZ9630469.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(9423..10931)
                     /locus_tag="J8S10_001887"
     CDS             complement(9423..10931)
                     /locus_tag="J8S10_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HAZ9630470.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            11090..11281
                     /locus_tag="J8S10_001888"
     CDS             11090..11281
                     /locus_tag="J8S10_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630471.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            11484..12401
                     /locus_tag="J8S10_001889"
     CDS             11484..12401
                     /locus_tag="J8S10_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HAZ9630472.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            12394..13467
                     /locus_tag="J8S10_001890"
     CDS             12394..13467
                     /locus_tag="J8S10_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630473.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            13615..14133
                     /locus_tag="J8S10_001891"
     CDS             13615..14133
                     /locus_tag="J8S10_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630474.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            14114..14506
                     /locus_tag="J8S10_001892"
     CDS             14114..14506
                     /locus_tag="J8S10_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HAZ9630475.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            14582..15517
                     /locus_tag="J8S10_001893"
     CDS             14582..15517
                     /locus_tag="J8S10_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HAZ9630476.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            15650..16429
                     /locus_tag="J8S10_001894"
     CDS             15650..16429
                     /locus_tag="J8S10_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HAZ9630477.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            16422..16739
                     /locus_tag="J8S10_001895"
     CDS             16422..16739
                     /locus_tag="J8S10_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HAZ9630478.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            16983..18593
                     /locus_tag="J8S10_001896"
     CDS             16983..18593
                     /locus_tag="J8S10_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAZ9630479.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            18750..19598
                     /locus_tag="J8S10_001897"
     CDS             18750..19598
                     /locus_tag="J8S10_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAZ9630480.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
     gene            19829..20308
                     /locus_tag="J8S10_001898"
     CDS             19829..20308
                     /locus_tag="J8S10_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630481.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNTDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            20341..22569
                     /locus_tag="J8S10_001899"
     CDS             20341..22569
                     /locus_tag="J8S10_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA domain-containing protein"
                     /protein_id="HAZ9630482.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKGRTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
BASE COUNT         7420 a         4040 c         4567 g         6548 t
ORIGIN      
        1 caatgaaaaa aactgttatt tatactagtt tatttgcagc tttgttttta gctgcttgtc
       61 aatcaaatac caatcaaggc acatctggga atacgtcttc cagtagcgaa cagcgctctt
      121 cacaggtatc ggactcctca acaaaagcaa gcacatcttc gtctagccag acaaaaagtt
      181 ctagtgaagc aagtactcag tcagatatca aagtgtctgc agctcgtgcg atcgaattgt
      241 tccaagataa atacccagat actgcaatta ctagtttgga attagatagt gattggggat
      301 cttacttcta caagatagaa ggtgtcgatg atcaaaaaga atacgaagca agaattgatg
      361 ctcaaaatga aaaaatggag acagagaatc cagaaactct agatcgagat gaacaaaatg
      421 gtcaaaagaa aaaagaagat ggtctggatg ttgataaatt gatcacgatt gaggaagcag
      481 caaaaatcgc cgtcgacaaa gtaggaagcg gtacggcaac agattgggat ttggataaag
      541 atttaggtac tacttattgg gaagtcaaag taaaagacgg caatcaaagt acatcagtca
      601 agatcaatag ccaaacaggc gaagtactgt caactgaaca agatgattaa gaatttcttc
      661 ggaaaacaag agttgatttt tcttttagtc atgatacact agacaaaata acttgtttga
      721 aggagcgatt tacttgagtt tagaaacgac ctttgccaat catatctttg ccaatccttt
      781 gatgaatgca tctggtgtcc actgcatgac tacccaggaa ttagatgaac tggctcattc
      841 agaagcagga gcatttatca ctaagagctg tacgatcaat gaacgaaaag gaaatcccga
      901 accacgctat tttgatgttc ctttagggag tatcaattct atgggacttc caaacttagg
      961 tttttcttat tatctagagt atgctcttgc gtatgaaaaa gtgcaggaaa accaaaatca
     1021 accgttattt ttttccattg ccgggatgag tgtccaggaa aacttggaaa tgcttgagaa
     1081 aatagaaaaa agtgggttta atgggatcac tgaattaaat ttatcttgtc ccaatgtgcc
     1141 tggaaaacca caactagctt acgattttga ggccacttat gaaacactga aagaagtatt
     1201 cagcatcttt tctaagccgc taggaatcaa attgcctcct tattttgatt ttgctcattt
     1261 tgatcagatg gctgatatct tgaatcagtt tccattgacc tatgtcaatg ctatcaacag
     1321 tgtgggcaat ggtttgtata tcgatacaga acaagaagca gtagtcatca aaccaaaaga
     1381 agggttcggc ggcattggcg gagagtatat caagccgact gctttggcga atgttcgcgc
     1441 tttttataca cgtttgaaac cagaaatcca aatcattggt acaggtggga ttcggacagg
     1501 acaagatgca tttgaacatc tgctatgtgg cgcaagcatg ttacagattg gtaccgagct
     1561 tcataaagaa gggccggaaa ttttttctag aatcataaaa gaattaacgc agattatgtc
     1621 agaaaaagga tatacgtcaa ttgacgaatt taaaggcaaa ttacgcacca tttcatagca
     1681 aagagacgaa ggtcatgatt gatcttcgtc tttttttata aaaaacactc gtctgttcat
     1741 tcctgtgcaa gcgtactcat tgtatgttag acgaacttgt gggaaaataa cagaggcaaa
     1801 aaggaggata atatgaatga tgcaacagaa ttagcaaaag agcttaaaga aaaagaattt
     1861 agttttcaag aactagttac ggatatacag aaaaaaataa agaagcaaaa tcatgaattg
     1921 aatgcgtttg tcgcgcttga accattcgag agtaattccc acgagctatt gattccccag
     1981 tcagaaaaag ggccattggc tggtatccca tttcctttaa aaatgctcgg tcaagaaaaa
     2041 aagggatggc tagctacttc aggatctcgt ttatttgaaa cacaccgagc ttctcataca
     2101 tctaattatg tgcggcaagc agaagcgata ggtctagttc cttttggaca aaccaatgcg
     2161 ccagagtttg gtttcaaaaa tattacagac ccagtcatct atggcccagc aagaaaccct
     2221 tggaaccttg aatgtacacc gggcggatca agtggaggag ctgctgctgc agtttcatca
     2281 ggaatcgttc ctttagctgg tgctagtgat ggcggtggtt ctattagaat acccgcttcg
     2341 ttttgcggat tgattgggct gaaaccttcg cgagggacga tgccagttgg tccatatgct
     2401 tggagaggat ggcaaggagc tgctattgat ttcggcttga cagtttctat gagagacacg
     2461 gaggctttat tttatgggat gagaagtatc cattccggtg cgccatatca agtatcgcca
     2521 gttgagtggc aaacacatcc aagaaaaaaa cggttgaaga tagctttttg tgttgattca
     2581 ccgatccact cacagattag tgaagaggca gtacttgctg taaaaaaagc tgtagatttc
     2641 cttggaaaag aagggcatga tttgacagag attccttacc cactagatgg tcgtaaactg
     2701 atcacgtctt attatcagat gaatggcgca gaaacagcag caatgatccg ctcgattgaa
     2761 acaggcatcc agcgagctgt cagaaaagaa gaacttgaac ccatttcttg gactttgttc
     2821 caatatggtc agaagctctc tgccgctact tacatcgatt ctctgcatgt atgggatgaa
     2881 gcagcaattg tcatggaaaa cctacatcaa gaatacgatc tattcctttc accaacgact
     2941 gcatttaccg cccctaaaat cagcgaagat ttgcaaagtg atgcgataag agcacagatg
     3001 gaacacatca gtgattgttc tgaagtagaa ggtttagacg ttgtttcttc catgtttgag
     3061 gagagcttga agatcacacc ttatacacag ttggctaatc tgactggaca accagcaatc
     3121 agcttgccta ctcatttgac aaaagaaaac atgcctctag gaatccaatt tatggctgcc
     3181 agaggaagag aagatttgct atttcaaatc ggctatctat ttgaagcaaa tcatcagttc
     3241 catttaccaa atccatggaa atagcagaaa caaggagaag aagaatgaag aaaaaaagat
     3301 tgtttgctct aataactagt gcctttttta ttttaagcgc ttgcggtaca gctgccgcta
     3361 atcaggaaga taacagctgg agtaatgtag aaaaaaagaa agaattagta gtagcgactt
     3421 ctggcacact gtttcccgca tcttattata atgatcaaaa tgaattagtt ggttatgatg
     3481 tagatttggc aaaagaggtg gctaaacggt taaatgtcaa aatctccttt aaagaataca
     3541 acgtggatgg acaaatcact tctgtttcaa aaagagaatc agattttgct gcgaacgatt
     3601 ttggtatcac aaaagaaaga gaaaaaaaat tctccctttc agagactttc aaatattcat
     3661 ttgacagtat gatcgtacga aaaaaagatg attcaggaat ccactcactt gaagatctta
     3721 aagggaaaaa agcagctggc gaacccaata ctagctatat gcgtttagcg gaaaaacacg
     3781 gagctaaatt agtcacatat gacaatgcca cgaatgatca gtatttaagc gatgtagcaa
     3841 atggtcgaac agatgttatt ctaaatgatt attatctgca gaaaatggcc gtatctgctt
     3901 taccagatat ccctgtaaaa atactggaga acgtttattt caatgaaaac gaaagtggtt
     3961 ttttattgaa agaaggaaat gatgctctga aaaagaaaat cgatggcgta ttaaaagaga
     4021 tgaaagaaga tgggacgaca aagaaaatat ctgaaaaata ttttcaaact gatgtttcag
     4081 tcaaaccgaa agaaacgatg gctgagtcgg tgagtgagtg atgtactttc ctctaattga
     4141 tttttccctc atgtggactt cacttccttt cgtactgcaa ggcttggtat acacattagg
     4201 gattggcttc gtgtcgtttc ttttaggaaa tctggtaggg ttgcttttga cagttttagg
     4261 tcttttggat tggctgcctc tgaatgtatt tattcgtttt tatttatcgt tctttagagg
     4321 cattcccgca ctagtcctgc tgtttctgtt atattttggg ttaccttatc aattaagtgc
     4381 cttaacggct tcagtcatct gctttacgat taccagcagt gcatttattg gtgaaatcta
     4441 tcgaggatca ctagcaggcg tttcttcagg tcagtgggac gctggtttag cttctggttt
     4501 ttctttcttt ggggtattga aatatatcgt tttgccgcaa gcttttcgaa tctcagtacc
     4561 ggcactcagt aacgtagcta tggatctagt gaaaggtact tcgttagcag caacaatcac
     4621 agtgccagaa atatttcaaa aagcaaagat cataggcggt cggacattcg attatttttc
     4681 tctctatatt ttagttgcac tgatttattg ggtcatttgt atcgggatcg aaaaagtgca
     4741 acagtattta gaaaaacgtt ctatgcatca gtcaatctga aaaatagaaa tggtgctagc
     4801 gtggctggca ccatttctat tttttgtttc ttgtatattc tgcctagtat tttaaaacca
     4861 tttcatgtaa aatgtaaatc gaaaatatgt tcggaggtag aaaacatgaa gaccccgcta
     4921 accatcgaaa tagaatcctc gttataccaa tattgcatcg agcaaggcgg cttggttgta
     4981 gaagaagtca cgatgcctga tgaccaagga attgtagata cgcttagctg cttgacaaaa
     5041 tttgatggaa gccgagaatg gcgatgctat gagctgaaag tgacaaaagc agattttcgc
     5101 tctacagcca aactgtcatt tgttggacat tataattatt ttgttttacc aagtaaacta
     5161 tatgaagaag taaaaactga aatccctaca ggaataggtg ttttagtgta tcgtccgtac
     5221 acggttgaag aggagatgcc tgcctctggt acatttctga ttgcgaaaaa agcagcaaag
     5281 aaagagcttg ctgtaccgga agaagctttg acaaaccgct tcatggcttc tttattcagg
     5341 gaagtaagaa aagcaaagca aatggagcga ggcgtaaaat attttccaac agatcaattg
     5401 tacaaagaat tgaaaagacg ttcagaaaat caagatccat tttctaacga acgatattat
     5461 gaacggtttt tagaggaaat agctagtcag gcaatcaatg agttgcaaga agaagttatc
     5521 gcgcttcagc atgattatga atatttgagg caacaacagc agatccgtcg gttgcctaca
     5581 gagccattgg agtgaaaaat atgtactatc cttatttaag aggaaaacaa tttgacctat
     5641 tagcattaaa agaagcactg tcgcgaggat tgctctccaa taaaatccaa ccagtgatcg
     5701 aaccagtacg tgattccgct acgcttaaaa atgtgatcga attatttcaa aaaaagcacc
     5761 atcgaatcgc tgtgatccaa aatccccaag taggacaatt caaattattc gatcagcatg
     5821 tgcacagttg gacagtcaaa gaaaatagct ctgtcgtccc tgcacagatc ttaacgccag
     5881 aaaatctcag tgaagtactg gattcacctc cagcgtttct tgttttcgat ggacagcact
     5941 acccaaaaga tacagaggtg tggaaacagt tggcaggagt tgattcgaaa tttttgatac
     6001 cagatactag tcgctttcgc atctggctgc ccgaaaacaa aattgtgatc cgtgactctt
     6061 ttcaaacgag aaagcatgtt gaaagttatg cagataaaac agatgacttt tttagtgatg
     6121 actatctttt tttccacgca gacggatata ttggattttc tgatttcacg atcgaaggta
     6181 gccgttattt cgataaaggg ttccctagcc gagcgcttgc tatccatcta acgtatattg
     6241 atgcttacgg caatatacgc gtgaaacatt ttgtctctga cagtaacgac tctgctaaag
     6301 accaagcatt gaagtttctt gaagcaggag ataaaatgaa aaaatggatc atgcgtcacc
     6361 atcatcaact cttgattact tcaggaatga ttgaattatt ggctctttac cagcaacaaa
     6421 aattccctgg actgggagtg ttgaaaaagt ggtcacttat gcatcatttg gaacttatta
     6481 gtcacctgct agatcatcca aaagattggc ttaaatatta ttcaaaagtt caggaactat
     6541 atgaagtgat ccaatgatta gataatgtaa atgaaaaagg aatagaaaag aggaaactgg
     6601 atgtatattc ggcaaacaag gaaagaagaa gtagaagaag tggtagaaat cattaatgcc
     6661 gcagcggatt tcattgcttc gcaaggctct cctcaatggc aaaacgggca gaaaccaaca
     6721 aaagaaacga ttttgaacga tattgaaaga aaagaaagct atgtattaat agtggaagat
     6781 caaattgctg gaacagctgc attagtctca agcgtggatc ccgtttacac aaaaatagat
     6841 ggtagttgga aagaatcaac tggtccttat ttatcgattc atcgtgtcgc tttagcagaa
     6901 agtactcgag gaaaaaaact agcaaaaccg ttcttagaac atttgttgac gattgcagcc
     6961 agcaaaaata tccaagatat ccgtatcgat acttatccag ctaatgaacc gatggaaaag
     7021 accatctatt ctgctggatt cacttatcaa gggatgattg aatttccttt tgaacacggc
     7081 gaaagaaaag catatcaaat aatcatcaat tgactataaa atcatctgag caaagataaa
     7141 gacattaaca ctactgaaaa aaacaatcat atgatagcca agaggttgta acagaagtgg
     7201 ccagcttcaa aaaacaagaa agaatttccg aaaatgcttc tcaaattttt gtggaatttt
     7261 agcgtatttt acgaaatagc tgctttctga aactcccttc atcgagaggt cgtgacatag
     7321 cttttgtcac gacctctcgg cttatcctac gagtattatt cgatacattt atatcaataa
     7381 tccttttttt attttatctg cagcttcttg gaacgctcca tcgtttgaca cgactaaaag
     7441 tgaggggata gctttcaaac gtttcaactg tgctaaatct tctacataaa ccgccagtct
     7501 ggctgaaatc tgttcagatg aatctccacg ttttttcagg cgcgattgca atgtttcttt
     7561 agagatcgta ataaagatag gacggactac cgtcccgaaa tactcatata aatgccaaaa
     7621 accatttgct gtcaaaacgg cgtaacaatt tcctactgtc agtttctttt taatttctgc
     7681 tttactggaa ccatatttat gttgagcata ttggtcccac tctgcaaact catttccctt
     7741 gatcatctga ttgaatgtat tgtcagaaac aaaataataa tcctcttgat ctttttcccc
     7801 aggtcttggt gatcgattcg tgtaagtaat gatcttttgt tccggctgaa aaatagcttc
     7861 tgcgagtgaa gtttttccag aaccagaagg accgataaat acatagcaat aattcattgt
     7921 catttctcct ttgatgattg aacaagtgaa aaagctttgg aaaatatttc caaagctttt
     7981 aaaagtaact ttgctttttt gtatattata ccagcaagcc agtcacaata gcacttaaaa
     8041 agctgactaa agtcgctgtt agcaaaattt tcaatccgtg ttttgcgaca agatttcctt
     8101 tttcttcatt taatcccttc atcgcaccag aaatgatccc gatagaagag aagttggcaa
     8161 atgaaacgag gaagacagat ataattgctg ttgtacgctc agtaaaatgg aaattaccat
     8221 ttgctaattc tgtcatagca acaaattcat ttgtaaccag tttagtcgcc atgatactac
     8281 cggcatccac tgcttctttc catgggattc cgctgatgaa ggcaagaggg gcaaagatgt
     8341 aacctaggat ctcttggaaa gtgatgccga atatcccgtg gaagatagca ttgatcatgg
     8401 caatcaaagc aacaaaaccg ataagcatag cagcaaccgt gatcgccaca tggaaaccat
     8461 caagaatgta ttctcccaac atttggaaaa atgtctgttc tttgttttct tcaatgatca
     8521 gctcatcttc tttttcttct aatacatagg gatttacaat tgaagccaga atataaccgc
     8581 caaataagtt caaaacaagg gcagtgatca catatttaga atcgatcagt gccatataag
     8641 atccgacgat cgacatagaa actgtagaca tagccgatac actcatggtg aacaaacgtt
     8701 tctcagatag gaagggtaat tcctttttta tggaaataaa aacttccgat tgtcctaaaa
     8761 tagcagaagc tactccatta taagattcca atttgcccat cccgttgatt ttacttaatc
     8821 ctagaccaac agctttcata aataatggaa gaatcttgat atagcgtaga ataccgataa
     8881 tagcagaaat aaatacaatt ggcatcaata cggaaagaaa gaaaggtgca cttcctttat
     8941 ttgctacacc ggcaaaaaca aagtcaacac cttgcccagc aaaagcaaga agatgatcaa
     9001 acatttttgc caatacagaa acaaccgctg taccaaaagt tgtacgtaat aatacgaaac
     9061 caagaacaag ctgtaaaacg aacatcacaa ttagtggttt caatttgatt gcttttttgt
     9121 tactgctgat caaaaaagca agccctaatg tgacaaataa accaataata cctaataaat
     9181 aactcaaata atcactccta ttccaaattc cgttttattt tacctgtttt gcaaataaaa
     9241 tactaatctt tagtgaaatt ttcattactt ttttagagtg aaacgcattc attttccatt
     9301 agaaaataaa gcgaacaaaa taaaaggttt aaaaagtgta acgtcttagt aaagtctata
     9361 aaaaaacgaa actatcgatt aagctaatag tttcgttttc aacatttata agtaaacttt
     9421 ttctattggt aatatagatt ttcggaaggg tagacaggtg cgcaggtaat atcgattcct
     9481 agttttttca atgtttgttc atcattttta ttgaccatca cagtagagtg ggcttgtgct
     9541 ccctcaagtt cagctagttt atcataagca acttgagcga ttggattcgt tactgcactg
     9601 attgataaag cgatcaagac ttcattgatg cttagtgcat ccaaagagga atgaagtgtc
     9661 tttgatttca atccttgtat tgtttcaaga actaatggtg acaataaagg aatgtcatct
     9721 gcgatatggg ctaaatgttt tactgcattt aagataactg ccgctgacgc atccatcaat
     9781 gaacttgtac gcccggtaat gatgacttca tctggtaatt cgattgcaat cacagcagaa
     9841 ggatcttttg taggactttg cgcttgaatc ttatctgcat agtcatgggc agggactacc
     9901 acgtttcggt cttcaggacg taaaccgact tcttccataa tcagtttgat tcgattaact
     9961 gcttcttcgt cgatcaatcc ttttttgaag tcgcattctg tttggaaata acgacggatg
    10021 atttcttgtt tagaggcttc ttggacaacg gtatcatcca cgatcccaaa tcctacacga
    10081 ttcacaccca tgtcagtagg agattgataa acagattctt taccagtaat tttttcaata
    10141 atacgtttga ttacaggaaa tgtctcaaca tcccgattat agttcacagc tactttattg
    10201 taggcatcaa agtggaagga atcgatcata ttgacatctt ttagatcgac tgtggctgct
    10261 tcataagcaa tgttcagcgg atgtttcaac ggaacattcc atactgggaa agtttcgaac
    10321 ttggagtaac cagctgcatg tcctttttgg ctttcatgat acagttggtt caaggaagta
    10381 gcgagctttc cacttcctgg gccaggagct gtcactacaa cgattggttt agttgtttca
    10441 atatactcat tttttccaaa accatcttct gagacgattt tttctacgtt gactggatag
    10501 tcttcgattt ctgagtgttt atagaccttg atgtttcgtc tttctagttt attgataaag
    10561 actttcgtgg caggctgtcc actatagcga gtgataacga cactgttgat taataagcca
    10621 taaccacgta attcatcgat taaccgcaag atatccatat cataagtaat cccataatca
    10681 ccacggatct tattacgttc aatatctcca gcatagacgc aaatcagtat ttcagcttga
    10741 tctttcaatt tttgcagcaa tttgattttc gcatcttctt caaatcctgg aagtacacgt
    10801 ttcgcatgct tgtcgtcaac tagcttccca ccaaattcta aatataattt gtcatagtgg
    10861 ttcactcgtt ccaaaatata cgctgactgc tcttcaatat atttttctga atcaaaacca
    10921 atttttttca ctaggttccc tccttaagta ctaaagcatt ttttcatttt tttgaggatt
    10981 cgtcaactgg aagagcgaaa ttcctcaaaa aaacaaagaa aatggtttaa accaacttgt
    11041 ctagatagtt attcattggt atgatagttt ttgataagga aggtgctaca tgaaaaaaag
    11101 acagaaaaag aaaaacgcat ataaacacta tatccgttcg atttttaccg gttatgaaag
    11161 aatgcttgaa gatcccgaat tggaacaatt gacgtttact tatctaaacg aagaaacgca
    11221 gctaactcgt gatgagcatc agcgcattca tttcacaaca agagatctgc ctagtaaata
    11281 aaaaataaga taaaggtcat cggattcgat tctgtcctat cagatggaaa gactagttga
    11341 tcgaaaaaaa ggctgtacca aattttggtg cagcctgttt tatggagcat tgcccgctct
    11401 tttttataac aattttttac agaaaatggt actattgaag tattaataag tgaaaaacag
    11461 atgagtaaga ggaggcaagt agtatgaaag agccagatac aaatgcaaat tatgagccag
    11521 acgaactaga ggagacgaat gcggatcagg atacaggaca agaatcgtct tctttttacg
    11581 atatcaaaga aaaagcaagc atgaatcttt cccaattatt agaagactta caggcttttg
    11641 aaaaagctgt ccgcgaagaa gatatccctg agatctaccg tttatacaat ggccgattga
    11701 atgaagaatt aaaaagaagc tcaaatgaaa atcacgagat cgatcaattg ctgatgcgta
    11761 agatccatga tcgtttttta caggaatttc cttttatgga acaagtagaa aacatctcgc
    11821 caacgatgag ctattacaaa atcggcactt attaccatga tcggcccacg gtcggtattg
    11881 atgcaagtct gccagaaatt tttgttttgc ctaagatcga tgaagagtgg gagaaatatt
    11941 cccaaccgga gtcaacggac tatgacaaaa aaatcaatga gctagacgca aaggtgatca
    12001 ctgctcagac agaaattgaa cgtttagatg aacaaataaa agaaatcaat cgacaaatga
    12061 ctgatttgaa cgacaataaa ggattcttga atcgtaaaaa aatcgaggaa gaaattcaag
    12121 aattagagaa gaagaagcaa gtactatcta atgaaaaatt aggctggctt ccttatattg
    12181 agacgcctga aacaatccag cagcaaaaag aagcattgaa gcaagaagca agagcagacc
    12241 agcttcgtgc agccatcgta gaaaaagaac aaaggcaaat cagacgctat ttcggtagca
    12301 aagagggatt cggtcaagca atccatgaat tcttgatgaa ttatcttggc aatgagaatc
    12361 ctaataatca atctaatgaa ggaggttccg agtatgaatg aacacgatga agcagaatgg
    12421 acaaaaaatg aagaacaaac agaagatcat gaagaaacga acacttcatt ggaagaacaa
    12481 acaagtaatc ctctggatga cacagaagaa atccctatgc tagaggaaac aaaaatacac
    12541 gaaaaagaaa aagtaactcc gacgaatacg aatactgcag aaaacaccca tgcttacgaa
    12601 ataactgaaa atcccgggta tttagaagga aaagagcaag atcatcaaga tatcgtcagt
    12661 ttgattgaaa cagcggaagc agaattagcg gatttacgta tgagaaaaga tttgatcgaa
    12721 tcagattttc cacaattatt agaatcatat gatcgtttta tattgaatga agaaccaatc
    12781 tccacgatcg gaaagacaag cctgatcgaa tacttcacgt atgaattact gaaaccgttg
    12841 aatgatattg gtctggaacg gtcaaattca gcttatgaca catggaaaac aagacatttt
    12901 tcgatcaatt atacgttgaa tggacaaaac gaattagtct tttcctttgt attaccgacc
    12961 atcgatcaac gataccaagt ggaatcgatg agtctcctaa acgtatcacc agagacaatg
    13021 gaaatcaatg tccaagatga ccgggtgctt tctttgatcc gacactggtc agtggatcga
    13081 gtattctctg cagggcagat cacgatattc aatcacaaat tgaatcaatt attagcccat
    13141 gcaagaacac ttggttttac cgttaatcag acattactag acaatacgaa gccacttcgt
    13201 ttgaatcttc agagcgaatt tgaattgacg aatgaagtat tggatgatat ttttatcgtg
    13261 gcaatgaaaa atccatccta cgatatggaa aagatcaacg aaactactta tcaagtacga
    13321 ttagataaag gacagtcttt aacgataaca acaaacgaaa aagatcaaac agtcttgtcg
    13381 atctcatctg gagactaccc acgatctgtc attgatttct ttatcaatta cgaattcttg
    13441 gtcccattaa tggtgagaaa gtcctgattg gataagttgg attaccagat gtcattcaga
    13501 taattctgtt ccaaaggact tgcggcagtt atccagaata attgtcacaa gtcttttctg
    13561 tatgtactaa atggacgtga ataacttgct gatgaaggag ggatttcatt aggaatgtcc
    13621 acaaataaaa tagcacagct tagcttattg tctgctgctt gtgtagcagg taggatcgct
    13681 tttcaattta ttccgaattt ccagccaatg actgctattt ttttatttat agtactttac
    13741 ttaagcttaa aagatgcgtt aattgtcatg agtctttcta ttgcgatcag cagtttttat
    13801 tttggtgttg gaccatgggt catcggccaa tggatcagct atactgttgt tctgagtttg
    13861 ttttcaatcg tctgcttgag aaaaacagtg caaaggaatc tatggttaaa gggagtctgt
    13921 ttttttctgg cgggcatggt ttacggaata ggtatgaccg tttttgatac gctgttatat
    13981 cgtttgcctc aaccttggat ctattacctt caaggggtgt cgtttgattt gatgcacagt
    14041 ataggcaatg ttgtgttctt tcttgttttt ctgccagtcg tcaaacgttt ttacaatcat
    14101 tcaggaggaa aaaatgaaaa aaataattta tagtttgctt gcaatgagtg tcagtatact
    14161 cattttgaca agttgcagta caacctatac acaatcggct tccaaccaaa aggaggaagt
    14221 aaaaacatcg caaaaagcaa caatcacgtt acaagaaaat ggtcaaaact tttcggaaaa
    14281 agaagtgttc ttcaaaaaag gcgatgattt actgagtatt ttgaaacgaa attttgaagt
    14341 caaagaagat aacggcttca tcacttcgct tgaagggcac tcacaggatg agaaaaatca
    14401 actctattgg atgtttactg tggacgggaa aagtgctact actggtgcca aagagatcaa
    14461 attgaatgat ggacaatcgg tcattttcaa tttgtctaaa ctataagttt cataaaaaac
    14521 tgttaaaggg cgaatattgc cataattcag tgagttcagt tgatgaaaga aggaaaataa
    14581 catggaaaat tttaaaaaaa gcggaatgtt ttccgtaatt gctgctctag gggctaatat
    14641 tctagttgct atcagcaaat ttgtcggcta tgcaatcagt ggcagtgccg ccatgctaaa
    14701 cgaaagcatc cacagtatcg ttgattgcag caatcagatt ttgctgttat tcggtgataa
    14761 acaagccaat aaaggacaga gcgagttgca tcaatttggt gaaggacgag caaaatactt
    14821 tttcagtaca atcgtcgcaa tgatgctttt cttcggcggt ggggcacttg gggtgatgga
    14881 agcttttgaa aagttgacgc atccatccca tgaagtgggt aatccgatca ttgttatagc
    14941 aatactgtta tttggtttgg taatcgaagg aagttcgtta cgcgtggcaa tgaaagaaat
    15001 caaagaattg aatactgaaa aactttccac gatgcgcttt ttgcgcgaaa gtcgacacag
    15061 tgaaatactg attattttta cggaagactt gtgtgctgta atcggtttgg tcttggcttt
    15121 agcaggaaca atattgactt atgcaaccgg gattgctgca tttgatgcga tcagcggatt
    15181 gctgatcggt ttcttgctga tgggagccgc cattttccta gcaaaagaat tttatagtct
    15241 gatcatcggt gaaagcgtga cagcaagcga tttatcaaaa atcaagttag cttttgaacg
    15301 tcctgagatc agtcggctga tcgatataaa aacagttcat ttaagtccaa cggagatttt
    15361 agttgcagca aaagcagata tcgttggtaa caaagagaat gaagcttact cggtcatcaa
    15421 tgatattgaa aaaaatatgc gtcagtctct tcctgacaag aagatgtata tatacattga
    15481 aacagataaa tatgacccaa attattctcg taaataaaac gtttattcat gaattgaagc
    15541 aaaaatgaga aaaatataat cttgttttta aataaaacgg ctacaattta gcgaatttat
    15601 gttacaatga gtccgctgtt tatttgttgt aattaaagga gatattttaa tgaacaaaaa
    15661 gaaaagtgcg ccatggcttc aagctttgca tgcagtgatg ccactttgta taagctatat
    15721 accagtagga ttagcttgcg gagtattgtt gcaaaaagtt ggatttgatc ctctcttatc
    15781 aggactgtta tcgattctgg tcttttccgg tggcgcgcag tttttagttg catctatgct
    15841 tacgacgcaa gcatcatttg caacgacatt attgatggtt ttctttttag aattacgcta
    15901 tacattatta ggagcaagtc ttgccggttt tatgaaaaaa gaaaagcgga cgtttttggc
    15961 tgtcttttct caatcactga atgatgaaaa ctatgcggtg aactacttaa agttttcaac
    16021 tgacccttcc tggaataaaa gaaaggcttt atatgtcaat tggttctcaa tgactgcatg
    16081 ggccggtagc aatatgatcg gtaatttttt cggctcggtg attcgagtag atgctgacct
    16141 tgtccatttt gctttgacgg ccatgttcat tttcatgttt atcatgcaga tgaaaagcgc
    16201 actactgatc tttacaggtt tattctcagg cgtattaggg gtcgtattca tggtattatt
    16261 ccaaaatact ttcggattga ttgcagcaac agtcattgct tcatttgccg gatttatgct
    16321 ggagaaggca ttcaaaaaag aaaaagctaa gaaactaaga gaccgcggta aagatgtcaa
    16381 tgagccgctc ttcaacttcc cggaacagga ggccaatcac catgactaaa ctatatttgc
    16441 tacttttagt tgcttgtctg ttcatcgtgg catatatccc gcgcttgttc ccgatgcttt
    16501 attttactca tcgaaaagtg ccatcctggt tcagtgactg gatgaaatat gtaccggtgg
    16561 cattatttgc ggcgttagct tttaaagatg ttttcattac tcatgaacat ctggatattg
    16621 cttggaatat caaaatagct gcaatgattc tagtagcagg cgtggcttac aaaacacgtt
    16681 cgatggcgtt gtcagttttg acaggacttg cgtctgtctt tttgctgtct atgctttaaa
    16741 ctgttttatt ttattaaaaa cagagattgc gacataagtt gttcaaactg atctatccga
    16801 actgcatttg caacagtcaa ttctggatgc aagtttattc gtagggataa aaaagattag
    16861 tgttggctta tgatgcaagc tcttttttat tttaggaatt agagagggat ttgtccttct
    16921 atgatttttt gctataatag ggaagatgtt tattttatga aagaatagtt gagggaattt
    16981 aaatgaataa aaaattgatg caaggaacat tttggctaac ctttgctaat cttctatgta
    17041 aagttttagg ggtagtctat ttgattccct ggctaagtat gatggggaac aatcaagatg
    17101 gtatgcttgc tacgacattg tataatgttg gctatcttcc ttatggattg ttcctgatgc
    17161 ttggtacagt cggatttcca aatgcgattg caaaaaaagt agctgtagcc acaaaagaag
    17221 gagataacgc tgcttgtcgg ctgattttta gaagtacgat caatatcatg tttgtcatcg
    17281 gtatcgcctc tgctgcactg atgtatttat ttgctccttt actagccgga atcagtccga
    17341 ttgctaacgt taataatggg atactagcta tcagaagttt atgcccatct ttgattgcta
    17401 tcccaattct tagtgcaatg agaggatatt tccaaggaaa aaatgatctg cggccttatg
    17461 gaacttcttt gattatcgaa caggctgtgc gagtgatcgt tatcttggct ggtacttatt
    17521 acttgcgcgt attgactgac ggaaccatat tagaagctgt attgatcagt acagtcgctt
    17581 ctttcttcgg tgggttagct gcgattatcc atatgtatat cgtcggacgc agaaaagact
    17641 tcttcgaact taaagatttt ttgatttcca gccgttattt cgaaagagaa aaccgatctg
    17701 cctctgtctc tatcattcgg gaaacactac cgtttatttt tgtcggctca gtcattacta
    17761 tcgttcaaat gatcgaccaa gtaacgatga aaccactgct tcactttttc cgtccagaga
    17821 tcgcagatca gcaactggaa ttcttattca gccgtgcttc tgtcaatcca aataaattga
    17881 cattgatcct gatctccatg gtaggaacag tagctataag cagcttgcca atattaagca
    17941 cgatgaagaa aaaagatcgg atacaaatcg aaaaaacagt aggagatagt ttttcgattg
    18001 cgttattgat tcttcttcct tcattgactg gaatgtcttt attagctgga ccactataca
    18061 cattgttttt tggctatgat cctgaaagtg tcggatattt ccaaatggct ttgctagctt
    18121 ctttgttttt ctctttattc acgatcctat ctacgatgct tcaatctttg aatcaccatc
    18181 gttttgcgat ccgattaact gtagaagcaa ttatcctgaa agtcatcttc caagtaatcg
    18241 gattaggatt agttggcgga tacgggatga gcttatcaaa tggcttagca ttcggtattg
    18301 tctttgttcg cggctatcac tttatgtgca aagaataccg aatagcacct ttagcaaaga
    18361 tcagcaattt tttcttaaaa actttccgct ccaccctgat tatgcttgca gtatgttttg
    18421 ccgttttctt tttgctgaat cagcgattgt caatggaatc aaaaagctat gcaatgattt
    18481 attgtgtggc tgtaggaagt attggcggct tagtattttt attttctcaa ttcggaaaaa
    18541 atgggtttcg aatgttgaaa aatgttaaac atcatagcag aagcaaagaa taggttaact
    18601 aatcgttttt tgctgtcact tgaaaaacgg caactcgtat gattacgctt gtcgtttttc
    18661 tattttccaa ttttagtttc atatctaatc ttacttatga tatagttata aggtctggaa
    18721 aaattctttg aaacgaggaa attaaacaca tgaaacttgc agtagttaca gatagttcgg
    18781 catatctgcc ggaacgtatc aagaaccatc ccgacttatt cgttattcca atccctttga
    18841 ttatggatgg gaaaatttat aacgaaggaa tcgatatcga agcggatgaa tattatggac
    18901 ttttaaaaaa cagtaaagat tttcctacta cttcacaacc tgtcgtaggg gaagttttgg
    18961 gtttatatga ggaattgaaa gagaaagggt atgacacgat tttaagtatc catctttctt
    19021 cagggatttc tggctttgtc aacacattat ttgcgatgaa agatgacatc agcggagtaa
    19081 cggtcattcc ttatgactct aagatcacta gtatgccgat gggacacatg gtagaagctg
    19141 ccttagactt aaatgatgaa ggtcagtccc ttgatgaaat acttgcacat atcgatcgaa
    19201 tccgagataa tacctacgct tatctgattg tagatgattt gaacaattta gtacgaggag
    19261 gacgtttgac aaatggtgca gcgctgattg gcagcttatt aaaaatcaaa ccgatcctga
    19321 cattttctga agggaaaatt gttttattcg aaaaaatccg ttcaagtaaa aaagcatttg
    19381 ctcgagctga agaaattatt ggtagaagaa ataacgaaat acaaccgcca gtcaaacttt
    19441 acgtgataca tgcaaataat ttagaagtag cgattgcgga gaaagagaaa ttgcagaaaa
    19501 aatatccaaa tgcagaaatc gaaattggtc atttcggacc agtcattggt acacatttag
    19561 gtgaaaaagc catcggcatt gccatttcag cgcaataatt ccttttattc aaaaaacata
    19621 ccaaaaatat tccaacatca tcttggactt tctacatgtt actaatgagc gtgtaaaaga
    19681 acgagatggt gtttttattt ctatcaatga agctcttttt ctttgcaatc ctcacttcaa
    19741 tcctctataa tgtcgcatat agtttagtaa atgagtaaac tactaattta cttatttact
    19801 aaaaataaaa ggatgaggag ttaaaataat ggaaatacca acaaatttaa aacataaacc
    19861 agtaatcgtt gtagaagact atgataaagt tgatggaaga aatgcattaa atacggatgc
    19921 aaaagggctt tcactgggcc ttgctcagtg gaatgatcgt ggaaaagtcg atatctcagg
    19981 caaggtatgg cgacatactg gagaaaaatg gtcacgacag tcggaagaat taccaatcac
    20041 acgtatttta gatttagcga tcttagctgc acaaggaagt ttatacttcc aagatgctta
    20101 tcgttatgaa aaattttatg atccagaaaa tccagtcgta gacatcattg gattacaagg
    20161 gaaccgaatg acggtagaag tagataccaa aaatccaaag atcgatgaag acatcatttt
    20221 gtattacgat acactacaaa aagacggaga actgattggg gaacgattcc gtattttaaa
    20281 acgtctttta gatgagctag gatattaata gacagagatg atcaaaaggg gaagagaagc
    20341 atggagaatt tctcactaac agaaaaccga accttttcac ggctagaaaa gcaaatgatc
    20401 tggaagaaac cgaaaagcca tcggacaagt gcagaagaat ggcggatcgc ctccgaaatc
    20461 aaagggaatt ggcaagatcc tgaaatgaaa atcagtaacg tacttttgga aggagatgcc
    20521 gggtcgggga agacacaatt agccaaagca ctatctgctg atctgcaact tccctataca
    20581 aaagtgacct gttttgcaga tatggacaaa tcagatgttt tcggagcctt attacctgta
    20641 gtagattcta ataaggaaca agaccaagaa ttactagaag ctatttacca aacagataca
    20701 cttgaagctg tactgacact gatccagaac cattacggca ttgatccttt ttctgctaaa
    20761 gaaaaattag cagagctagt tcaaaggatc gaagctgatt atccagatgc aatccattac
    20821 agctattacc cttctgaaat cgttcgagcg attgaaaaag gatatttatt agagattcaa
    20881 gagccgactg tcatccgaga tgcctctgtt cttgtggcac ttaactcagc gctcgaacca
    20941 aatgggatgt tgaatttacc gacaggaatc attcgtcgcc atccagattg cgtcattgtg
    21001 atcactacaa atcgaaatta ccaaggaaat cgcccattaa atgaatcttt aagagatcgg
    21061 atgcaacatg cggaaaaaat ggatcttcct gccttagaag tcatggcaga acgtgcgatg
    21121 gcgaaaacta tgatccaaaa acaagaactt ctcttaaaga tggcagagat tatccgtttg
    21181 ttggatgaaa ctgcaaaagc taacgccatc aaaggtgtag caggaatgcg ttcttatttt
    21241 tattgggcaa atacctataa gcaaggacaa gatttactcc agtcgattta tccaaaagtt
    21301 ttgtataaat tatccactga ttcagatgaa ttggcaattc ttgaacaagc tttgtctgac
    21361 agtggattgc tactggaact tcaggacata ttgagaaaag aaaaatgggg tcatcctcaa
    21421 tctgagcata caaaaggaag aaccattagc gccgaagaag caaatgaacg aaacatcact
    21481 gaaaatgctg aagaaattct gcgcttagat gaaaagaaat cgttgtctgc tgaagaacca
    21541 aatgagggag aagagaaaca agaagaaaca atagaaaaaa acgagattcc tcctcaaatg
    21601 caaaaagaac gcagtagcga tatcgaagga aaaaatcaaa aagaacaaca aacaggagat
    21661 gattctcaag aaatgtctgc ttctgacatg gaagcacatg ataaggaaat caagaagcaa
    21721 ctgaataaag aagcgcgaca aatcatgaag gaaacgattc atgaaaaaga aggtctcatc
    21781 gttcaccgac cagctttcca aggaaaaacg ccggaagcac gtgagctaca catgcaagta
    21841 atgccaatag tagaatcact tagccggcaa attttagagt tactggataa tgaacaaaca
    21901 gagacgtacc aaaaaggaaa atacgaaggt cagcggttca atgcaagcaa agtagcatat
    21961 ggtgatttga gaaattttga caaaaagaac ccgccacatg agcaaccttc tttagcggta
    22021 gctgtacgga tcgatgaatc tgggtcaatg atacgggatg atcggatcga agcggcaaaa
    22081 aaagcagcga ttgccattgc cgaattttct aagaaagtcg atatcccatt gttgatttac
    22141 ggagatacag cagaccgttc gtcaagagaa aagacttctt tgttttctta taaagaattt
    22201 gaagacggat ttcaatggtt aaatgaaaaa ttagtcacta tgaaaccaag gcaaaacaat
    22261 cgtgatggtg ctgcacttcg tttagcagca gaaaaattaa acagacaatc cgcaacaacc
    22321 aaactgttgc ttaatattag tgacggtcag ccaaaagcgt tgccggatta tacaggcaaa
    22381 aaagcaaaag aagatatcca gtctgttttg aaagaatatg aacgtcaagg aatcctattt
    22441 gtctccgcag ctattggcca agacaaagaa gaaatcaagt cgatctacgg tgaaagtcgt
    22501 tttgtagata ttactgactt gaatgaattt cccaagcaaa tgattcaact gattgcccgc
    22561 tatctatgat aaaat
//
LOCUS       DADQDV010000048        22423 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.048, whole genome shotgun sequence.
ACCESSION   DADQDV010000048 DADQDV010000000
VERSION     DADQDV010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22423)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22423)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22423
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.048"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            6..305
                     /locus_tag="J8S10_001900"
     CDS             6..305
                     /locus_tag="J8S10_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAZ9630483.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="J8S10_001901"
     CDS             378..1739
                     /locus_tag="J8S10_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HAZ9630484.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="J8S10_001902"
     CDS             1761..2021
                     /locus_tag="J8S10_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630485.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="J8S10_001903"
     CDS             2035..2787
                     /locus_tag="J8S10_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HAZ9630486.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="J8S10_001904"
     CDS             complement(2881..3486)
                     /locus_tag="J8S10_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAZ9630487.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3539..4513)
                     /locus_tag="J8S10_001905"
     CDS             complement(3539..4513)
                     /locus_tag="J8S10_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HAZ9630488.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4891..5670)
                     /locus_tag="J8S10_001906"
     CDS             complement(4891..5670)
                     /locus_tag="J8S10_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAZ9630489.1"
                     /translation="MLLRVVGSIIFRYTLEEVNNVPKYEEIANILRERIRSKEYPLDS
                     FLPNQVDLVKEFGASRMTIKKAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEY
                     EGLSLQMKRRHRSLKSQIIHFDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVL
                     EHTFMPVHLVPGLKKEHLLASIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAE
                     NDPVLEVQQVVYLKDGQPIEYSSSRNRFDVRNYSVLDVRST"
     gene            complement(5737..7008)
                     /gene="celB"
                     /locus_tag="J8S10_001907"
     CDS             complement(5737..7008)
                     /gene="celB"
                     /locus_tag="J8S10_001907"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HAZ9630490.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7161..8558
                     /locus_tag="J8S10_001908"
     CDS             7161..8558
                     /locus_tag="J8S10_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAZ9630491.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8639..9079
                     /locus_tag="J8S10_001909"
     CDS             8639..9079
                     /locus_tag="J8S10_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAZ9630492.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9227..9553
                     /locus_tag="J8S10_001910"
     CDS             9227..9553
                     /locus_tag="J8S10_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAZ9630493.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9554..10303
                     /locus_tag="J8S10_001911"
     CDS             9554..10303
                     /locus_tag="J8S10_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630494.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10383..10838)
                     /locus_tag="J8S10_001912"
     CDS             complement(10383..10838)
                     /locus_tag="J8S10_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HAZ9630495.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
     gene            complement(11265..11540)
                     /locus_tag="J8S10_001913"
     CDS             complement(11265..11540)
                     /locus_tag="J8S10_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630496.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            11834..12649
                     /gene="thiD"
                     /locus_tag="J8S10_001914"
     CDS             11834..12649
                     /gene="thiD"
                     /locus_tag="J8S10_001914"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HAZ9630497.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(12978..14429)
                     /gene="cls"
                     /locus_tag="J8S10_001915"
     CDS             complement(12978..14429)
                     /gene="cls"
                     /locus_tag="J8S10_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HAZ9630498.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            14770..17436
                     /locus_tag="J8S10_001916"
     CDS             14770..17436
                     /locus_tag="J8S10_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAZ9630499.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAILEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            17800..18552
                     /locus_tag="J8S10_001917"
     CDS             17800..18552
                     /locus_tag="J8S10_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAZ9630500.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(18574..19728)
                     /locus_tag="J8S10_001918"
     CDS             complement(18574..19728)
                     /locus_tag="J8S10_001918"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HAZ9630501.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYSLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            19913..22354
                     /locus_tag="J8S10_001919"
     CDS             19913..22354
                     /locus_tag="J8S10_001919"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HAZ9630502.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
BASE COUNT         7198 a         3932 c         4673 g         6620 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttagaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcatgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtcttg ttgctgcctt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattgcca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcatc actatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgatttagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaagggccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcagaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgtgaaat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc ttgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccagtc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa tgaagtagca tgaagagatt
     3541 attcacgttt tttatttgca tcacttgtat cgaaaggacg gacataagct tcaatggctt
     3601 cacgacgttc ttctaagaat ggaggaagag atagtttttc tcctgctgat tctgctggtt
     3661 catcttcaag gaatccagga ccatcagttg ctaattcaaa cagtacgtga tgagcggcta
     3721 ggaagtactc agattggaaa tagaaacgat cgacgaaacc agaatttggc aattcaatct
     3781 tattgattac ttgaatccag tattccaatg cttctttgtc tgctacacgc aatgctaagt
     3841 gatggatatt tccaaatcct tcgattgctt ttggcaagtc tgtccgatgt tcaataatga
     3901 tgcttgcacc atttccccct tcaccgattt caaataagta gaaatctcct gaatggtctg
     3961 tttctttgaa tcctaagatt ttttcaagaa tcaagcggat atgctctaat tgactgacac
     4021 ggacaaagac aggtccaagt cctgtgatcg caaactctgt cggtacattg ctgtttttcc
     4081 aaggaatgcc agctgctaca ccttgattgt tttcgtcaga gatcaattga taatactgat
     4141 tatcgaaatc ttcaaattcg atatattttt tgccgaaacg ttcattgatt gctgaatgag
     4201 taacgtcata tttttcaaaa cgttccaacc aaaagtctaa tgctgcgtca cttggcacac
     4261 ggaaagaagc acgagagatc gtatctgttc ctttttttcc ttttggctga tttggaaaat
     4321 caaagaaagt catatctgtt cctggcgcac cagtatcgtc tgtaaagtaa agatggtaag
     4381 tttcgatgtc atcttggtta actgtttttt tgattaagcg cattcctaaa atatctgtaa
     4441 aaaagcggta gatttttgta gcgctagatg tcattgctgt gacgtggtga attcctctga
     4501 tttgtgtatc catgataaat ttcctcctgt taacttacaa aaagtaagta gttgatttag
     4561 acatagtata gagggtgcat ctctattttg caattaattt gtcttctaaa gtatcaggaa
     4621 ggaatcaaga atggaaaaga ggagggacgg atcaataaaa taaaaagact tacgactagc
     4681 tgtatcgatt tcaaaaaaac tagctttaaa aagctaactt tagaatcatt acgggtggtc
     4741 ataagtcttt ttatgctgag ttattttttc atttttgagc taatgcttag gatagaatag
     4801 aatgttgatt tcacgatctc ttcttgttac ttgaaactgc ttaccactgt cacgatctct
     4861 tggtaaacgg ctttttcaca acctctttgg ttaagttgaa cgcacatcca gcacagaata
     4921 gttccgaaca tcaaatcggt ttcggctgga agaatattca atcggctgtc catctttgag
     4981 atagacgact tgctgaactt ccagtacagg atcgttttct gcacagttca aatattgctg
     5041 atcatattca tcacttttat ctgcagaaat agcacgataa gcccctgcaa aatggacatt
     5101 caattcttga tgaagatgat catagataga ggctaacaaa tgttcttttt ttaaacccgg
     5161 cacaagatgg actggcataa aggtatgctc taaaacatat ggctcgccat ctaagatcct
     5221 taaccggtga atattgtaga caggttgctc ggcatcgatc atcaatcgtt cttggatata
     5281 ttgattaggg aattcaacat caaaatgaat gatttgactc ttcaaagaac gatgtctgcg
     5341 tttcatttgg agactcaaac cttcatactc gttagcgggc gatgtgtctt tttgcataaa
     5401 tggatgattc aagattttcg ttcctgatcc tcgctgcgaa tagacaagtc cttccattgc
     5461 taagatattg atggcttttt tgattgtcat ccggctcgca ccaaattctt ttaccaagtc
     5521 gacttgatta ggcaaaaaac tatcgagagg atactctttt gaacggatac gttctcttaa
     5581 aatatttgcg atttcttcgt attttggcac gttattcacc tcttctagag tataacgaaa
     5641 gattatgctt ccgacaactc gaagtagcat ctggaacatt gtttattcga aaaaagaggt
     5701 catgacaagt ttttgtcaca accccttaat gatctattaa gcaatatcta aatctggttg
     5761 tttatctagt actttcagga atgggtacca gataaaggca acgatgacaa agtcgatgac
     5821 ttgcagcata ccaccaagcc atgaatttgt tgctaagaca ccgcttgcaa tgattggcac
     5881 agtccatgga acagagacgc cagttggtgc agggacaagt ccagcagcca ttaccaaata
     5941 attgaacgtc gttacgatta gaggtgccac aacccaagga ataaggattg ttgcattcaa
     6001 tacgatcggt agaccgaaga tcgctggttc atttacattg aaaataccag gtgctaaagc
     6061 taatcgtcca acatcacgat actgtttctt tttaagaaca aaggccatca ataaaacgac
     6121 agctaaagtc attccagagc caccaatacc aacagtgaag gtttccatga atggttttgt
     6181 gatgatgtgt ggtaattctt ttccatgttg ataagcttct aagttatcaa gcatcagtgt
     6241 attccaaatc gggtccatta cagagttgac gatgatttgt ccgtgaagtc cgaagaacca
     6301 taagaattgg acaaagaaca aagcaatcaa tgttgcaggt aaactacttc ccaaaccagt
     6361 taatggtttt tggatcactt cataaacgac gtcatgtaag ttagcattga aaataccagt
     6421 catcacagca ttgattacta agaaaatagt tagtgtcact acagcaggga tcaaagcggc
     6481 aaatgatttt gttactgcag gcggaactcc atcaggcatt ttgatctgcc agccgcgttt
     6541 cgtgattctg cagtagattt ctccagccaa gaaagcagcg atcattccaa tgaacattcc
     6601 ttttgcgcca agacgatcaa gtgaaagcac accagtcaca tcttcaccgc cagcggtttt
     6661 cattgcaaaa ggcgtaagaa tcaagaagct ggcaaaagac acggcaccac cgaaaatacc
     6721 ttcaacgtca taagattttg ataaataata gccgatacca aaagtaacaa aaaccgacat
     6781 gatgctcatt gttgcatttt gcccattacc gaataaattc gataaagttc cctttgttgc
     6841 gtcactgaaa aaaggcaagt tattgataac gacaacgatc gaaccgaaca tcgttaaagg
     6901 gaaggaaagc atgaaagcat cccgcagcac tgtaaggtaa cgattttgcc ctaataaatt
     6961 agctaagggc atgattttct cagaaagctt gtccataaaa ccgttcattt ttattcacct
     7021 caaatttatt tgcaatcgat tacatacaaa gtataacgcc aaaaatttta aatgtctagt
     7081 cattttcata aaaagtattg atttattttt tagggttcgt tatgattacg gtatcaagaa
     7141 aaaagagagg aagtaaaaaa atgaaaacct acacattccc agaaaatttt tggtggggtt
     7201 ctgctgctag cggaccgcaa acagaaggaa gagtaagtga tgatggtaaa ggagaaaata
     7261 tttgggatca ttggtatgaa ttagagcctg aaaaattctt cgatcaagta ggacctgaaa
     7321 aaacttcgca agtttacaca aaatacaaag aagatgttca gttaatgaaa gaaactggcc
     7381 ataacacatt tcgtacatct atccaatgga gtcatttgat tccagaaggg acaggtgaaa
     7441 tcaatcaaaa agctgtttct ttttatcgag attattttac tgaattgctg gataatggta
     7501 ttgaaccttt tgtgaacctt taccatttcg atatgccact accactgcaa gaaaaaggcg
     7561 gatggttatc aagagaaacg gtcgacgctt atgtttctta tgcagcagcg tgctttgaac
     7621 tgtttggaga tctggtcaaa aaatggttta ctcataatga accaatcgta cctgtagaag
     7681 gaggctactt gtatcaattc cactatccaa atcatatcaa tatgaaagaa gcggtccaag
     7741 taggctatca tgagaatcta gcaagcgcaa aggtaatcaa agcctaccat gaaggcggac
     7801 atgatggtga gatcggaatc atcttgaatc tgacaccaag ctatccgaga gatgaaacga
     7861 acccagaaga tgtaaaagcg gcgaagatcg ctgacgcatt cttcaaccga tcattccttg
     7921 accctgcagt gaaaggagag tttccacaag agttgatcga aattgtcaaa gaattggcta
     7981 taatgccaga gatccatgaa ggagacctag aactcatccg tgaaaacacg attgacctgc
     8041 taggaatcaa ttactatcag cctcgtcgaa tcaaagcaaa agaaactcca atcaatcacg
     8101 aacatagccc catgccagat gattattttg ataattacga catgcccaat aaaaaaatga
     8161 atccatatcg tggatgggaa atttacgaaa aaggaatcta tgatatttta acgaatacaa
     8221 gagaaaacta tggtaatatc aaatgctata tttctgaaaa tgggatgggg gtcgaaggag
     8281 aagaacgatt tgttaacagc gaaggaatta ttgaagatga ttaccggatc gagtttgtta
     8341 cggatcattt gaaatacgtc catcaagcaa tccaagaagg aaccaattgt gtgggttacc
     8401 acatgtggac atgtatggac aactggtctt ggacaaatgc ttataagaat cgctatggct
     8461 ttatcgctgt tgatttggca caagacggta aacggacgat caaaaaatca ggtcgctggt
     8521 ttaaaacggt ctctgaaaaa aacggatttg atgcctgata ttttttgata aaacgttcac
     8581 aaaatgtttg ttctaacact gtaatcgtgc tacactaaca gtgaaggagg cgtttacaat
     8641 ggtagatact tatcgtaata ttttagtagc aattgatggt tctgaaaagg cagaaaaagc
     8701 atttcttgag gcaatcacga ttgccaaacg aaatcaggca acgttgcaca tcctgtatgt
     8761 caatgaagta acaggcaatt actttggtga ttttgcattt gttacaacaa gccttcagga
     8821 agaattggat gaggttgcgg aaaaccagat gaaagaacat cgaaacttgg caattgaaaa
     8881 aggcctgaca gatatcgaga catatgttct ttacggttat ccaaagacac tgattgctaa
     8941 tttccatgaa tcgaaagaac caatcgatct gattgtcatg ggggcgacag gtctgaatgc
     9001 ggtagaacgt gcactagtag gttccactac ttcctatgta gtcaaccacg catcatgtaa
     9061 cgtcatggtt gtaaaataaa taaattaagg gaacagaaag caaaaaagca taacgcttct
     9121 tttgctttct gttcctttta tttttttgta aaaaattact ttacctgatg aagtaatcat
     9181 gctattctaa ttacaacgac agatggagta atatggagga aagaaaatga tttcaagtga
     9241 tggaatacgc ggatacaatg atgcgattat tttatcgatc cttaacaaaa acgattctta
     9301 tggatatgaa atttctaaaa cgattcgtga gaggacaaat gattcctatg tgatcaaaga
     9361 gacaacactt tactccgttt ttgcccgttt agaaaagaat caactgattg tttcgtatcc
     9421 tggagaagtg actcatggaa aaaagcggac atattataaa atcactgaaa tagggcgtaa
     9481 tcttttagaa gaaaaaaagc aagagtggct gacgacgaaa gacgtagtcg atcaattttt
     9541 ggagggaaat taaatggata caatccgtaa ttatttagac agtcttttta tcggagtacc
     9601 tcaaagtacc gagatagata agctgaaaac tgatttgttg gcaaatatgg aagaccatta
     9661 tcatgaattg atgggagaag gaaaaaatga acaggaggcc atcggtacag taatttcgac
     9721 atttggttca atcgatgaat tattagaaga actagatgtc gaaaaaaaac atcaagctga
     9781 cgagacggaa acaaacacag cttctattta tttaagcgaa gcagaaaact actggaaaga
     9841 atacagagcg gcaagtctcc aagtggcatc aggtgttcta ttcattagct tatcttttgc
     9901 aagttttctt ttcttttgtt cagcaggata tgtgttcatg ggtatttctt gtctgatttt
     9961 cggtatagca ttagctgtcg gtttttttat tgcttctggt atgaaaatca cacgtttaaa
    10021 tcactttttg caccatcgga aaatacctga aaaagtatta gcagaagcaa aagaaaaaga
    10081 agaagagtat cagcgaagtt ttggcttctc actgattgca ggaattggat tatgtatttt
    10141 ttcacttttc ccacttttgg cttctttaat gtggtatatg gatggtagta tcggtgcctc
    10201 tatatttttt gttacggtag gaacgggtgt cttcttgatc atttatggca gtctagtccg
    10261 tcattcttat cgtcaattca ctcaaagcgc ttattactgg tgaatgtatt cagatttgta
    10321 aaaatattct atttatccgg cgtagaaaaa aagactgtga cacgcttttg tcacagtctt
    10381 ttttatatat aataatttaa aaattcatca tctaaatccg tagaattttc tagattgctt
    10441 acccatgtaa aatcgttata gacagatttc agttgacttc tgcgccattg tacagggata
    10501 aaaagacgca tgctatcttc attgaatccg actaataatt tctttccgtc agtaatgatg
    10561 ggacgttgta acaaagtaaa atgcgagacg atcagatcga caagctctga ggtcgtacat
    10621 tggtcgattt ggtctttcaa atttttataa tcaatcgagc gtttagctaa tagatcgtca
    10681 aatccgtttt ctgttaatga caataaataa aatatctctt tccttgttaa aggctgttta
    10741 ggtgtgaaaa ttcgttctct gtaaggcatt tgatggtctt tcagccagtt tgccatcaga
    10801 tggtaactat gtgtgcgaga agaatagatc gtaagcataa aaaaactcct taaatagtcc
    10861 attaatttgt tagatctgtt gagataaata ataggtaagg agctgtgcat aagcattgat
    10921 caaaacaacc caaacatcat tagaaataac tttctaaagt cttaaacttg cgacgagaag
    10981 caactagact aatagaaaaa atgtcttagc catttggctt cctgtttgtt tttttgctta
    11041 tgctgcagct cctcgggaaa gggttctaac aatttgaaga aggttgatga ttgatctagt
    11101 ttaaattgtg tgaaatttga aatctggtgt ttttactaga tgaatcacct aacaactatg
    11161 attataactt atagaacttc tgttttgcat tcggttttgt tatagttgtt ataaagtttt
    11221 attttattac agaacatttt taattaataa agaacagtta gaagttaaaa ttgctgattc
    11281 acatagagtt tatgacttct tggaaattct ttttcaatca gttttttcat ctgtttatga
    11341 aattcttttt tttcagtaaa cataaaggtt tgggtatcgt aaccttcttc atgtaggaaa
    11401 tagattattc ctttttctgt gttttgcgta taagctttta tactcctgtc ttttttgaaa
    11461 gaacagatcg tatagccatc tatttggtct ggtagtcgtt tgattttctt caaaatgact
    11521 tttttatcct caagtttcat ttttttcacc tgactttatt tttttcatat ggaaatcata
    11581 gcgcctttgg ttatatgaaa acaagaagga tactgaaata tatataaatc aaatagtggt
    11641 tatttattat tagaatagcg aatacaaata aacgaccact attttctgat ttattgcaaa
    11701 tgttttttca aataaatttg attaccaaga aaaggtagtg gtatatttac tgagggatac
    11761 tttgaaaaac atatgataga aacagtaaca gtattatgaa aaatcttttt ataaaaatgg
    11821 aggaatcgat ttgatggaag atcagtatgt acaagcaatg acgatcgcag gatcagatag
    11881 cgatggaagc gcagggatgc aagcagatat gcatacattc tttacaagaa atgtttacgg
    11941 tgtttctgtc atgaccgcat gtgttgcagg taattcttac ggaatcggag caagtgtgac
    12001 attgccaaca gattttatcg acaaagaatt tgaactgatt gcgaaggact ttcaaatacg
    12061 tgcagctaaa acaggtatgc tagcagattc aaagttgatt gagacagttg taaaaaatta
    12121 ccaaaaatat gattttggac cattagtcgt ggatcccgta atcgtaacga aacatggaaa
    12181 tcttttacta gaagaatctg ctttgcaaag cttgaaagaa aagcttgtcc ctttggccga
    12241 agtactgaca cctaattttt atgaagcaga aaagctgact ggacggacat tagcagctga
    12301 agaagatttt gtgcaagcag caaaagaact gcaagatatg ggtgcaaaaa acgttatgat
    12361 caaaggacat catgctaaaa atgcgcagca agaaacagtc aatgactacg tattgttcga
    12421 atcaggaaaa tcattttggt taaatgcacc attttatcct accgaccgga tcaacggaac
    12481 tggcgattcg ctatctgcat gtattgcagc tgagttagcg aaaggaaaaa cagttgaaca
    12541 agcgatccga ttggcaaaag actatgtaaa ccgtgcaatt cgtgaagaaa taaatgtagg
    12601 gcacaaatat ggccccatca atcattgggc agctggtgaa ttagagtaaa agaaagaagt
    12661 tgtgaaaaag ttgccctgca tcaagtaata agaacagcca agtaaaaaca gcttcttatg
    12721 tttttaactt ggttggactt attaccgcag atgcaagctt ttgaacaccg tttaagaaag
    12781 aggtcgtgag cctgccgtcc agctccgagt cacaaggaac aagttcaaaa aacagcttct
    12841 catgtttgtt gaatattgtg acttgtgacc gaggagttgg caggagaaca ccgtttgttc
    12901 ggaagaaggg actgtgacaa gatttttgtc acagtccctt taatcttagt atatttttct
    12961 ctacttgaat aaaaaaatta taggattgga gaaaataatc gagaaatttg ttgcttgaat
    13021 aatagccagt tagacatttc cttgactgtt tcagttgtca tggatgaaca atgtgtctca
    13081 tcttctttga actgagtagc aagttcttct aaaaactcag gatcgtaaat gacagcactt
    13141 gtttcaaaat tcaatcggta gctacgaata tcttgatttg ctgaacctac catgcagatt
    13201 tcatcatcca ttatcaatgt ttttgcatgg aggaagccgt tctcatagac aaggatttgt
    13261 acattttcct tgatcagctg ccgagcataa tattgtgttg ctcgataaat aaaaggatga
    13321 tccggtttgt tgggaatcat gattttcaca tctacaccag aggcagttgc gatttttaaa
    13381 gcagcaatga cactttcatc aggaacaagg taaggtgtct gtatccaaac acgtttttta
    13441 gcagaagtaa tcaatttgat aaatgaaagc ttgatttgtt ccctttcgtt attcggtccg
    13501 cttgaaacaa gctggatgga tgtatcagca agcttagatt catctcgatc tgctttttta
    13561 aagaaataat tcaaatgata gccgaccttt ttttcttcag gtaccgagac gttccagtct
    13621 gttaagaagc gaagctggag caaagaagaa gcggcaccga aaatccgtat atgcgtatcg
    13681 cgccaatagc cgaatttttt tgttgtattt acatattgat tggcaatatt gaaaccaccg
    13741 gtataactaa tctttccatc gatcacaacg atttttcggt gatcatggta attcaatcgg
    13801 aaacgaagta atgccctttg tgaggtaaca aatgtatgga catgtccacc atttttgatt
    13861 agacgattga aatcttttgc ttttgtgcca tgagagccaa atgcatcata taatattcga
    13921 acttccacgc cttctgcggc tttttcttct aaaacatgta agacttgctg gccgatatta
    13981 tctgtcacaa atgcgtaata ttcgatatgg atcgaatgtt tggctttttt tagatcttga
    14041 agcagtgaat ccaatttctc ttgtccgtct gtgagaagag tgacagaatt cattcttgtc
    14101 agcggcatac gatttaatga agagaagaag tcaacaaatt gctgtttgtc tttatcgccc
    14161 atgtcaggat cgtaatgttc aatggtatct cctctaaaag actgaaagtt ttctaattct
    14221 ttcaagtcac tttgtcggag atagaatttt ttcttatccg ttaatccacg tccgaaaaat
    14281 aaatataata caaagcccac cccaggaagg gcaaacaata ctaagagcca tgcccaaatg
    14341 gctgctacat ctcggggttt gatcaaaata gccaccaaag caataagtgc atttaataga
    14401 taaagggcgg ttataatact agataccaca aaaatgttcc tccttacata caataacatt
    14461 agtatagcat gatagaagaa agaagcctac caaggtgaat atacttttca ctcctttcat
    14521 gaaaatgtag gtaaatcggg ctaaagtagt tgctttttgt aggttaataa ggtaggatat
    14581 tagtacagtt gaatatctcc ttaggggagt aaccggcaac gtttgttgcg ataatatcaa
    14641 cagtaagtta accaaatggt tttctggtat tgtatgaaat ggtgagacct aagacaaatg
    14701 cgtatttgtc ttaggtctct tttttttcag acaggactag ggccaagatc aaaaaatggg
    14761 ggatgaaatt tggaaaacaa ggaacaagca caacaagcgg tctataaaga aacgatcgac
    14821 tcgttgatgc agcaaacgca gagctcaacc gatggattga gcaccacgca agcgaaggaa
    14881 aaattagaaa gagatggctt gaaccagcta aaagaaaagc cgaagaagcc aacttggaaa
    14941 ttgttcttag aaactttcaa agatgcaatg gttatcgtat tgctgattgt cgcactgatt
    15001 cagatggtca tgggtgacta catcgaattc ttagttattt ttgcagtatt gatgttgaat
    15061 tctataatca gtgttgtcca aacaaaaaaa gcagaaggtt ctttagaagc gttgaaaaac
    15121 ctttcagcgc ccgatgctcg agtgattcgt gatggtaagg aaaaaacgat tccggcaaac
    15181 gaacttgtgg taggagatat cgtgttgtta gacgcaggcg attatgtacc tgctgatgga
    15241 cgtttactag atgcgggatc attaaaagta gatgaaggta tgctgacagg agagtcgact
    15301 tctgcagaaa aagaagtaac ggatatcaca agtacggtac caatcggaga tcgtacaaat
    15361 atggtattca gtggaacgat cgtaacttac ggacgcggta aattcttagt gacttcaact
    15421 gggaataata cggagatcgg acaagttgct ggccttttgg aatcaacaac tgagcaagtc
    15481 actccgttac aacgaggtct ggataaattc agtaaaaaac taagtttggc tattttggca
    15541 ttgtctttat tgattttagg tatccaactg tttcgtattt atcttggaga aggtacagga
    15601 gatatgactg cagatatcgt cagcgcagtg atgtttgccg tagccgtagc cgtagctgct
    15661 attctagaag cattacagtc tatcgtaaca atcgtgttat ctttgggaac gaataaaatg
    15721 gcaaaacgtc atgccattat tcggaagctt ccagcagttg aaacacttgg ttcgacaagt
    15781 atcatctgta cagataagac tggtacattg acacaaaaca aaatgacagt tgttgactac
    15841 tttttaggta atggcgatac tggggatttc acaaatgacc cttcaaaatg gacagctgac
    15901 gaacgtcgct tgatcgaaat cagtgtttta gcgaatgatg catcgatcag tgaagacggt
    15961 actaaattgg gcgaccctac ggaagtagcg tttatcgact ttagtgaaaa attaaaccag
    16021 ccttatcagg aaatccgaaa caactaccca agacaagcag aacttccttt tgactcagat
    16081 cgaaaattaa tgtctactgg acacacaatt gataacaaaa attacttgtt tgttaaaggc
    16141 ggaccagata tcgtcttcca acgcagtaaa aaagtattgc taaatggtga agtcgttccg
    16201 atgacggatg aattgatgaa aaaattccaa gagcaaaatg aagctttttc aacacgcgca
    16261 ttacgtgtac tagcttttgc ttaccgtcca cttgataatt ttgatttatc atttgaagat
    16321 gaagacgatt tgatccttgt tggtttgctt gctatgatcg atcctccacg tgctgaagtg
    16381 actcaggcgg taacagaagc aagaagtgca ggaatcaaaa caatcatgat tactggtgac
    16441 cacaaaacaa cagctgttgc tatcgcaaaa caaatcggga tttttgaaga aggaaacctg
    16501 gctttgaccg ggacggaact agatgaattg acagaagatc aactaaacga agttttagaa
    16561 aaagtcactg tttatgcacg tgtttcacct gagaataaaa ttcgtatcgt tcgtgcttgg
    16621 caaaataaag gtcatatctc agctatgaca ggtgatggtg taaatgacgc accagcattg
    16681 aaacaagcag acatcggaat tgctatggga acgggtacag atgtggcaaa agatgcagca
    16741 gcgatggtat tgacggatga taactttgct tctattgtca gcgcagtaga agtaggacgt
    16801 aatgtgtttg ataatatcaa gaaagctatt tcttatctat ttgcaggaaa tttaggtgcg
    16861 atcattgcga tcatctttgc cttagttgct gactggtcca atccatttac agcattacaa
    16921 ctgttgttca tcaatttagt caatgattca ctgccagcaa ttgcattagg tacagaaaaa
    16981 gctgaacctg ctacgatgaa ccgcccgcca agagatccaa attcaggaat ctttacggac
    17041 aaaacattga tttctgtaac gtatcgtggt gtgctgattg ggattgctgt tatctttgct
    17101 caatggcttg gcatgcagca ttcacctgaa ttcggtgtag ccatgtcatt ttcaacattg
    17161 atttggtgtc ggacattgca aacattccca gcacgttcaa acacacaaac agctatccaa
    17221 gcagggttct tctctaacag aagtgtctta ctagctgtag ttgtatgtag cgcgctttac
    17281 tgcttaacaa tgatcccagg actgaaagaa gtcttctcta tcccatcagc atttggattg
    17341 acagaagtct ttacatgtat gggaatcgca cttgtgacaa ttgttttgat ggaaatcact
    17401 aaattgatca ttgtacgagt acaaggaaat aaataaaacg aatcaacgag gttgtgagcc
    17461 tgccgtttaa ttctgagtca caaggtgcaa tttcaacaaa cagcttctca tgtttgttga
    17521 atattgtgac ttgtgaccga agagttggca ggagaacacc gtttaaggaa gaagttgtaa
    17581 aatcagcatt ttgagctaat actgagggtc atctgattgg acactgttta ttcggaaaga
    17641 gggactttga cacgactttg gtcacagtcc ctttttttat ttatgataga cggaaagcca
    17701 atcattttat tattcatcaa aagagataga atagataaaa gaggagaatg atttattccg
    17761 aaaagtgaaa acatataaca aaaaattaga ggaaatcaaa tgaatgaaaa agaatgggat
    17821 gaatttgctg aagaatatta tgaaatccag caagaatcgc aagtaactat tgctgaagat
    17881 gtaaaaaatt atctgaaaac ggagaaagtc ctgcctgctg aaacagcagc agacgttgct
    17941 ggaggatctg gcagatttct ttccttagca aaagaaatta atcgctatga tttgatcgat
    18001 ttttcttcag gaatgctaga aaatgcaaaa aaagaagcag aaaaaaatga gttgccaaat
    18061 gtttccttta tcaaacagtc gttagaagaa tttatccaat caaatgagac atatgaaatg
    18121 gtttttacag cagcaaatcc agcattggta catcttattc aattagaaaa attgatgaaa
    18181 aagtcaagca aatggtgcgt gataatcaga gtagtggaat caatcgatga tgttttttat
    18241 cctatcgaaa agcaactagg aatgatagaa gaagatccta atacatcgcc agttgtaatg
    18301 gatcaatttg aaacatactt aattgatgaa ggattcaaag tgaagaaaaa agattttact
    18361 tattttacac aggaatcaat tactgaagaa ttgatgaagc tatactatga cgcgtacgca
    18421 aaagatcctg ttgtgaccag gtacattcgc aaactattca gtgaaaaacg agaaatcctt
    18481 agtacgacta agctgaccta tagactgctc ctttggtccg cagataaaaa aagaaccttt
    18541 cacgactcgt gaagggttct ttttatgatt ttattatatt ttgtagtaac gaatatcatt
    18601 ttcgatcttt gtaatcgaaa aaggtacatc tgaagtatat tctgcacatt ctccgtgttc
    18661 aggaagcgtc tcactgaaaa tcgtttcata ttcgtcaaca gtgatccgtg ttcgagaatc
    18721 tagcatctct tgatgagatt gtgcgaagag atattcttga tagttttctt ccagataacc
    18781 tgtaaaaaat tcacttactg caccagaacc gtagctgaat agaccgatgc gatctcctgg
    18841 ctgtagtgat ttcgaatttt ccagtagaga agttagcccc aggtataatg aaccagtgta
    18901 aagattaccg attcgtcggc tgtaacggat gctttcttca tagcgagcca taagacgttc
    18961 ctgattttct tcgtctgttt ggtctaatac gctttgcaat gccttttttc ccatcttagt
    19021 atacggaata tggaaagcaa tcgcctgata atcttcgagt cctcgacccg acaattcttt
    19081 atgtcgattc caaacttttt ggaatgattc gatatacgta gaattagata aaggaccatc
    19141 aacaacagga aattcgctat aatctggacg ccagaaatca tagatatctt ctgtcagaaa
    19201 tacgctgtcg tcttcaatcg ataaaatacg cgggttttga gtgatcatca tcgcaacagc
    19261 accgacacct tgcgtcactt caccaccgct tgccaagctg taacgagcaa tatcacttgc
    19321 tatgactagt acttttcgtt ctggatgatt tttgacatat tctttcgcca tgtgcaaagc
    19381 tgcggtgcca ccgtagcaag cctcttttac ttcaaaagaa cgagcaaaag attggatttt
    19441 cagtaaatgg tggataatta ccgcactcgc ttttgaatga tcaatcccgg attctgttcc
    19501 gacgatgacc atgtcgatta gctcacggtc tttttctgtt acgattttgc tggcagcatt
    19561 tgctcctagt gtaatgatgt cttcatttgc acgattgact gccatttggt cttgaccaat
    19621 ccctatatgg tattttgcag gatcatcccc acggctttct gccaactctg tcatatctaa
    19681 atataaatta ggaataaaaa aggaaagacg atcaatccct attttcattt caacacctct
    19741 ttacttatga taaaaaactt actttactaa ggtatcataa aaagattaaa agaaatataa
    19801 aaaagagaat atttaaggat tgttaaaatt taatcttaga aaaaaataac tggaacaaga
    19861 gctatttgtt tttacagcaa agaatggtat atttttgtag gaggtggctt acttgaaaga
    19921 agtcgttatg atagatgctg caagaacgcc gataggaaag tatcgcggaa gtttaagtcc
    19981 atttactgca gttgaattag gcacacttgt gactaaagga ttattagata aaacaaaact
    20041 gaaaaaagat aaaatcgatc aagtaatatt tggaaatgtc ctgcaagctg gtaatggtca
    20101 aaatgttgcc agacagattg ctttgaacag cggtctccct gtagatgtcc cagcaatgac
    20161 gatcaatgaa gtttgcggat ctggtatgaa agcagtgatc ttagcacgcc agctgatcca
    20221 attaggtgaa gcagaacttg tgatagccgg cggaacagag agtatgtctc aagcacctat
    20281 gctgaaacag tatcagtcag aaacaaatga atatggtgaa ccaatttcca gtatggtcaa
    20341 cgacggattg actgacgcat tttcaaatgc acatatggga ttaaccgcag agaatgttgc
    20401 aacacaattt tctgtgagca gagaagagca ggatcgctat gccttgtcgt cccagttgaa
    20461 agcagcacat gctgtcgaag ccggtgtatt ttctgaggag atcatcccag tcaagatttc
    20521 tgatgaagac gtgttatctg aggatgaagc agttcgtgga aatagtacat tggaaaaact
    20581 gggcacgtta cgtacagtat tctcagaaga aggaactgta acagcaggaa atgcttcccc
    20641 gttgaatgac ggtgcctctg tggtgatcct tgcatccaaa gaatacgcag aaaataataa
    20701 tctgccttat ttagcaacca tcaaagaagt agcggaggtc ggtattgacc caagtatcat
    20761 gggaatcgct ccaatcaaag ccattcaaaa attgacagat agatcaggaa tgaatttatc
    20821 aacaatcgat ctttttgaga tcaatgaagc atttgcagct tcttctatcg tagttagcca
    20881 agaactgcag ttagatgaag aaaaggtcaa tatatatgga ggagcaatcg cattaggcca
    20941 tccaattggt gcaagcggtg cacgtatctt gactacatta gcttacggat tgcttcgtga
    21001 acagaagaga tacggtattg cttcattatg tattggtgga ggtttaggct tggcagtctt
    21061 gttagaagcg aatatggagc aaacacataa ggatgtgcaa aaaaaaaagt tttatcagct
    21121 tacgccatct gaacggcgca gtcaattaat agaaaaaaat gtattgacac aagaaactgc
    21181 gttgattttt caggaacaaa cactttctga agagctctcc gatcacatga tcgaaaacca
    21241 agtgagtgaa gtggaaatcc caatggggat cgcgcagaat tttcaaatca atggcaagaa
    21301 aaaatggatt ccgatggcaa cagaggaacc atctgtcatt gcagctgcaa gtaatggtgc
    21361 aaaaatctgt ggaaatatct gcgcagaaac acctcagcgg ctgatgcgag ggcaaatcgt
    21421 tctatcagga aaatcggagt atcaagcagt gatcaatgca gttaatcatc gaaaagaaga
    21481 gctgattctt tgtgcaaatg aaagttatcc ttcaatcgtg aaacgcgggg gcggtgttca
    21541 agatatctct actcgggaat tcatggggag tttccatgca tacttatcta ttgatttttt
    21601 agtggatgta aaagatgcaa tgggcgctaa catgatcaac tcgattcttg agagtgtggc
    21661 aaacaagtta cgggagtggt tccctgaaga agagattcta ttcagtattt taagtaattt
    21721 tgctacagaa tcattggctt ctgcctgttg tgaaatccca ttcgaacgct tagggagaaa
    21781 caaagaaatc ggtgaacaaa ttgccaaaaa aatccaacag gcaggggaat atgcgaagct
    21841 tgacccttac cgtgcagcaa cgcacaacaa agggatcatg aatggtatag aagctgtagt
    21901 ggcagctaca ggaaatgata cacgtgcggt tagcgcttcg atccacgcct acgcggcaag
    21961 aaatggatta taccaaggat taacagactg gcagatcaaa ggggataaac tagttggaaa
    22021 actaacggtg cctttggctg ttgccacagt aggcggagct tccaatatcc tgccaaaagc
    22081 aaaagcatct ttagctatgt tagatattga ttcagccaag gaactagcac aagtaattgc
    22141 tgcagtaggg ttagctcaaa acctggctgc tttgcgtgca ttagttacag aaggaatcca
    22201 aaaaggccac atgggacttc aagctcgttc attagcgatc tcaattgggg ctattggtga
    22261 ggaaatcgag caagttgcga aaaaattacg tgaagcagaa aagatgaacc agcagacagc
    22321 tatacaaata ttggaaaaaa tccgggaaaa ataaaaaagc aatatcttta gaagaataaa
    22381 gcaagattta cagttatttt atttactgca gatcttgctt ttt
//
LOCUS       DADQDV010000049        22301 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.049, whole genome shotgun sequence.
ACCESSION   DADQDV010000049 DADQDV010000000
VERSION     DADQDV010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22301
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.049"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            5..403
                     /locus_tag="J8S10_001920"
     CDS             5..403
                     /locus_tag="J8S10_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HAZ9630503.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
     gene            387..1082
                     /locus_tag="J8S10_001921"
     CDS             387..1082
                     /locus_tag="J8S10_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HAZ9630504.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
     gene            complement(1676..2563)
                     /locus_tag="J8S10_001922"
     CDS             complement(1676..2563)
                     /locus_tag="J8S10_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rotamase"
                     /protein_id="HAZ9630505.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            2748..3587
                     /locus_tag="J8S10_001923"
     CDS             2748..3587
                     /locus_tag="J8S10_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAZ9630506.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            3783..4757
                     /gene="sgrA"
                     /locus_tag="J8S10_001924"
     CDS             3783..4757
                     /gene="sgrA"
                     /locus_tag="J8S10_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HAZ9630507.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            5055..5411
                     /locus_tag="J8S10_001925"
     CDS             5055..5411
                     /locus_tag="J8S10_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630508.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            5414..6571
                     /locus_tag="J8S10_001926"
     CDS             5414..6571
                     /locus_tag="J8S10_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630509.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(6597..7037)
                     /locus_tag="J8S10_001927"
     CDS             complement(6597..7037)
                     /locus_tag="J8S10_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HAZ9630510.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            7197..7703
                     /locus_tag="J8S10_001928"
     CDS             7197..7703
                     /locus_tag="J8S10_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAZ9630511.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            7871..9784
                     /locus_tag="J8S10_001929"
     CDS             7871..9784
                     /locus_tag="J8S10_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HAZ9630512.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            9789..10790
                     /locus_tag="J8S10_001930"
     CDS             9789..10790
                     /locus_tag="J8S10_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAZ9630513.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(10992..11198)
                     /locus_tag="J8S10_001931"
     CDS             complement(10992..11198)
                     /locus_tag="J8S10_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HAZ9630514.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(11844..12692)
                     /locus_tag="J8S10_001932"
     CDS             complement(11844..12692)
                     /locus_tag="J8S10_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAZ9630515.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            12856..13758
                     /gene="gnd"
                     /locus_tag="J8S10_001933"
     CDS             12856..13758
                     /gene="gnd"
                     /locus_tag="J8S10_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HAZ9630516.1"
                     /translation="MEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDI
                     PAYQEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSI
                     RRAEEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLY
                     AGASGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWL
                     MEIMEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEED
                     SFSAKVVSALRNGFGGHEIVEKGE"
     gene            13760..14761
                     /locus_tag="J8S10_001934"
     CDS             13760..14761
                     /locus_tag="J8S10_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HAZ9630517.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            14758..15042
                     /locus_tag="J8S10_001935"
     CDS             14758..15042
                     /locus_tag="J8S10_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAZ9630518.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            15075..15872
                     /locus_tag="J8S10_001936"
     CDS             15075..15872
                     /locus_tag="J8S10_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAZ9630519.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNVAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            15886..16719
                     /locus_tag="J8S10_001937"
     CDS             15886..16719
                     /locus_tag="J8S10_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAZ9630520.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            16737..17594
                     /locus_tag="J8S10_001938"
     CDS             16737..17594
                     /locus_tag="J8S10_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAZ9630521.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLKQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            17616..18125
                     /locus_tag="J8S10_001939"
     CDS             17616..18125
                     /locus_tag="J8S10_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAZ9630522.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            18162..18563
                     /locus_tag="J8S10_001940"
     CDS             18162..18563
                     /locus_tag="J8S10_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630523.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            18675..19028
                     /locus_tag="J8S10_001941"
     CDS             18675..19028
                     /locus_tag="J8S10_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630524.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            19062..19505
                     /locus_tag="J8S10_001942"
     CDS             19062..19505
                     /locus_tag="J8S10_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAZ9630525.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            19522..20607
                     /gene="uxuA"
                     /locus_tag="J8S10_001943"
     CDS             19522..20607
                     /gene="uxuA"
                     /locus_tag="J8S10_001943"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HAZ9630526.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            20600..21313
                     /locus_tag="J8S10_001944"
     CDS             20600..21313
                     /locus_tag="J8S10_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAZ9630527.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
     gene            22065..22265
                     /locus_tag="J8S10_001945"
     CDS             22065..22265
                     /locus_tag="J8S10_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAZ9630528.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
BASE COUNT         7682 a         3427 c         4620 g         6572 t
ORIGIN      
        1 agagatgacg atctttgaaa cggttgtaac agatgttggt atagaagcag aagtattcag
       61 gaaagaaaaa ataatgattt tatttggaga tgaagcaccg gaaacattaa cagattattg
      121 ttataagatt gaattgaatc aggtaagaaa agaaataact tgtgatatga agctctgttt
      181 tgataaacaa atgtatgtaa tcacagcagt aggagatgtt gtccaaacta atttgaatga
      241 attaggacat atcacgataa aatttgatgg atctcatgag ccggaacttc caggaacaat
      301 gtatgtagaa gataaggaaa tgccgcattt aagaaagggg acaatcatta aaatcgatca
      361 agaggatcag aatgggggaa agctatatgg aaatcatgct tgatacagca aatacaaaaa
      421 gtatttattc ttgtcaacag tttttgaatt taacaggcgt aacaacaaat cctacaattc
      481 tgaaaaaaga aggagcgtca aacttcttct cgcatatgaa agaaatcaaa aaaataatcg
      541 gacagattcc tatccatatt cagacaatag gaagaacgga agaagaaatg atagaggatg
      601 ctcgagttat catagaagaa ctgggaaaag atacgtttat caaggtgccg gtgaatcaag
      661 caggccttca agcgatcaaa aagttgaaaa aagaaggtta tttgattacc ggtacagcta
      721 tttacacaga attacaaggg tatttagcta ttaataatgg agcagattat attgcacctt
      781 attataacag gatgcaaaat caaggcattg atgctatgaa agtgattgat tcgttgcgga
      841 ctgagatcga acgtacgcaa agaccaacaa aaatattagc agctagtttc aaaaattgtg
      901 aacaagtcac tacagccatt cgatctggag ctcatgcgat aacgttaggt aaagagctac
      961 tagatcaagt attagagatg ccctcgattg ataaagcagt gaggggcttc caagaagatt
     1021 gggtgcaaac tttccaagca gaaacgattg gtgaactaaa aaaggtcgct gattacttct
     1081 gaatcaattt ctccataaaa taaacgatag ccttctcgaa aactcgagga ggctatctga
     1141 cgattcaata ttcattaatt taaagtttgg gtgactatta ctaactatta cttatttctc
     1201 atttaaacga tgtattccct aacctctaat acatccttgt aactctgaag ttacgccagt
     1261 tttgaataaa tttcataaaa acaaatgaaa agtgtcgcat aaaaatatct ttcgtgtttc
     1321 tctagtataa cagaataaga agaacaagtc cagaagggat atttttagtc ttttttaaaa
     1381 taacttttca gtcgagtttg agtttatgat agttgttttt gaagcgatac ggcaagtgaa
     1441 aaaataggga agcatgaaag aatctactta atggcgcatt gattcatgtg atagaaataa
     1501 aaaacttttt taaattatat cctcatgatt gtaacaaatc cagtgatttg ttttggtaca
     1561 aataaaaaaa ggccccgatg aagttgtggc aaaagtggtt tgcctcaaaa ataagaagga
     1621 atttccaaaa atcacttctc aaattttgcc acatccccaa ttgggtcaaa tttgtttatt
     1681 tgaatatatt ttttacataa ggatctttaa tagttacatt gtcttttttc atcactttac
     1741 ggattgtttt atccatgaat tccgtatcaa gagtttttgc ttcggtagca attttttcta
     1801 gctcagattt gtatttgtct ttattagaac ctttatcctg tttttttacc atttttacta
     1861 gataatagct ttgctgataa gtcgttggat ctgttacagg aatgatatca gaaacttccc
     1921 cgttttttag tttaaatgct gcttttttta cttcagtagg aatctctgga ttggttgaat
     1981 caaaattcat ttttccatca gtttccttta atgttttatt ttttccataa gcttgaacaa
     2041 gcttggagaa attttctcct tcatttgctt ctttttttgc tttatctgct tcttctttag
     2101 tcgaaaatag aatgatctgt gtactaactt ctggatagaa ttctttccaa gcagtgtcta
     2161 gatctttatc tgttaatttt acattggctt tcaaaccgta ttggaaagcc agcatctgtt
     2221 taaagagttt cttatatgtc tcttctgttt ggccaactgc ttttaattgt tccttgtagt
     2281 ttggaccgag ttttttgatt tgttcattat attcttttgt tacttccttt gaagaaatct
     2341 cttttccgta tacatcatca aatgctttga agacaatcat tttttttaat agtgtttgat
     2401 tatttgattt aacttttggg ttatcataaa aatcctgaac tgtaagtgtt ccacctttaa
     2461 acgttgcaat cgtttcattg gacttgctac aacctgagaa tagtaaaatt gcacatgctg
     2521 aaaggcacat aattagtagt tgttttttca aaaaatttcc catcctttcc ttattaaaaa
     2581 cagtctaaca gaagaattag ggagacagtc tttcattttc gtaaggttgc tgtagatatt
     2641 cttagttcgt aaaaatctat tctctctatg atggagaaca tttacatagt tttcacgaga
     2701 caagaaagaa aagggttgtt aaacttaata taaaggaggg atgaaagatg atcaggatta
     2761 ttcggttgat tggatctgtt ttaatagtct tagttggttt tgttttagga attcttgtca
     2821 ataatgcact tgcggatatg tttattggaa atagtgaatg gattggagca attgccggta
     2881 cggtcggaca tttagctgtt tttttactag ctttatttct tgctagtaag gtcgaaggaa
     2941 aaagaataga agattatggt gtttctgttc gaggaaaaga ctgggggtat ttagcgggag
     3001 gtctcgttgt tggaattgga gtgtttctgc ttattactag tccattatat ttgacggggg
     3061 cgtatcggtt agattcagga aacgcaaaca ttgtgccgct gataacgagt tttattttat
     3121 ttattgcagt gggggcatca gaagagcttt tattccgtgg cttttttcag catcagatgc
     3181 ttagatttgg tccgttaata gcaatgattg gatctgctgc attatttgct cttttgcacg
     3241 gattgaatcc taacatgaca tttctggcag ttttcaatat ctttttagca ggttgctttt
     3301 tcagcgcact tatctacagt acaggaagtt tatttacggc tattggtgct catattactt
     3361 ggaattggac acaaggagct attttgggta taccagtcag cggaacgcaa gaacaaggtt
     3421 ttttctccac tctgatccaa tcgcaaaata caataattac tgggggaaac tttggggctg
     3481 aagcatctat atcaactaca ttattcttgt tagtcttgat tgttggtttg ttactctatg
     3541 catataaaac aaagcggatg aagaaataca ctgctgttta tcaataaaag atgaagaaag
     3601 caaggctgat atcggtcttg cttttttaag tctgtcattg attaaacgaa aaagtaaaca
     3661 aattcaagcg aatacacgac atcttttgtt agattttcac aactgactgt cgtgttctca
     3721 tcattttcat tttatataat tcctttatca aatagaaggt aattatatgg agagtgatag
     3781 aaatgaagaa aacagcgacc gtattatttg ttattcttgg gctgagtata attgcagcaa
     3841 tgattggaat cagtacttct gcaaatgaac gggcaaatga gaatctttca tttactgtga
     3901 aaactgatcg gattgtttat gacatgacac aacaagtcat tactattcca gtcaaaccaa
     3961 acaaaagcgt gaatgctagt gatgtacatg ctgttctaac atatggttgg gatggtaatg
     4021 gaagttcaga aaaagttatt ggggaagttt atttaaaaga cgtacaatgg accgctggta
     4081 ttgagtatac aataatgatt tctgcagaac tatcgattga tgagatcaag agtaaagata
     4141 aagttgattt gattgttttt tatgatggac agatgacgat cacggagaat ttgaaaccaa
     4201 gcagttggac agttgttgga ccgccaagca gtacggatag cacaagtagt gaaagcagta
     4261 cagaaaacac gagcggtgaa agcagtacag agagtacgag cagtgaaagt agcacagaaa
     4321 acacgagcag cgaaagcagt acggagagta cgagtagtga aagtagcaca ggaagcacga
     4381 gcagcgaaag cagtacggag agtacgagta gtgaaagtag cacaggaagc atgagtagtg
     4441 agagtagcac aggaagcacg agcagcgaaa gcagcacagg aaaagtaaat aatgaacttg
     4501 atttggtacc tatcatacca actaaggaac aaaagagaaa tgcagggagc aacctaaaaa
     4561 gtgtgctaaa acagcctgat tttgtttctc gtggaattga tcatcaagaa aaagcgaaag
     4621 aaacagataa tagaaaaagc gatttaccag aaactggtag tagaaccttg aacaagctaa
     4681 ttacatggat gggtgtgtta ctcattttga ttgtaggagc aagctatttt cgttctctct
     4741 tccatcgagt gaaataaaga ataaaagcaa cagatctaaa attgaataaa acgatagatt
     4801 tttgagtgaa tatttcattc gagagtgctg tattgcctgg cgaagttgta gctttgccag
     4861 atctattttt gtttactaac atatttgaga aacaggaaat aacaggaaca caaatggaaa
     4921 ataagagcaa gaataattga caatgcacac tgcgcatggt agtatctctg aaaaatcagt
     4981 aacgaatcta tttgtacgtt attcatgtag ctgtcggaat aagtctaaat aatagataaa
     5041 aaggagtatg tactttgttt gaagaattta ttgatatcaa tgaaaggcaa gtatatcaat
     5101 ttttgaacta ttgttatgaa agagacgaga aattatatgt ggtgaaggat atcgctttag
     5161 atctaaacta caccctggct aagatgaatt cggtgattca acaagcagaa tcgttttgcg
     5221 aaaggtatcc agaatataaa ttatcttttc tttcagaaaa caagatgata aaagtcgagt
     5281 tttcttctca gtttttactg agtaaagttt attctatact tttagaggga acgattggtt
     5341 atattttact ggattcactt tacaaaggta cttatcaatc cttagaaaat cttagtcaaa
     5401 aaattatata agtttgcgta cgattcaaag aaaattaaga gaacttaata ctattttgaa
     5461 aaactatcat ttatcttgca gcttgaaaaa aggtaatccg atagaaggag aagaataccg
     5521 tatccgatac ttttttcact tgatgtattg gcagtcattc gacgaaaatc attctgatat
     5581 attatcaagt ataaaaaata aacgtcaact attagaaaaa tttgcgaaac atgcgccata
     5641 tacgcgtagt atagatagaa agaaatggat cagcctacta agaatttcgt tgcaacgaat
     5701 gaaacaaggc cactcgatta cgtatgtccc agaagagatg aacaaatttg tgcatccatt
     5761 gataacaaaa gaagagttta cgcattacat actagagcct ttttttgaag caaacttctg
     5821 gtcgatgaat cacatcactc caacagagca agcttacctt tattttatgt ttggtgtaat
     5881 gaacacctat ttggaagaag atttgttgga tactccagat aaagtacaag aaagttgggg
     5941 ctggattgaa tcgtctattg tagaaaattt tgaaaaaaac ttcaagattt gttttacaac
     6001 ttcagaaaaa aattatctat atgtcaattt ggcaatgatc catttgtatt caagggtttt
     6061 tgggacaaaa aagaaggtgg atgcttttgg aaaatcagca gaagacagag attttcagca
     6121 tatatttcca gtgatgtatc caatcatgca acagtttttt agtggggtag ctcgcagaat
     6181 tccagagctt aatacttatt atgaaaagaa cagacggttg atttttcaat actgtatgtt
     6241 agtcagggat atttttataa aacacgaaca acctgtcata ttctatattc aatcaaagta
     6301 tggtaaaaca caggaattat gggcaaagaa aaggatatta tctatgactg aacgcccaat
     6361 aaaatatagt gcatccgctg atcagttacc tgatattgtc attagcgatt atcctatcga
     6421 caaaaaggca tatgatcaaa cgaatacaca gatattttac tggaatggac aacctacaaa
     6481 aaatgattgg gcgcgtctga aagctgaaat cataaaaatc aggaatgaga aaaatagatc
     6541 catattggaa aaattggatt tcgttaatta agaaaagcag attgtttatg ccaaaattaa
     6601 gacattgcaa aaagattatt ttctttaaaa tcgacaagat gaccagaaag caagagttcg
     6661 ttgagctctt gctttctttt agttttagaa aggaacatcc tgattttatc ttcgctaaat
     6721 ccagtcaaaa gttttgcaga ttggtcgtag ataatcggtt ttttcaataa agaaggggat
     6781 gtacgaatct caatatatag ttcactcaaa ctgagttcat ctattctgtg aacaagattt
     6841 ttataactaa tagaatgagt agagagcatt tcggtcacgc cgttgtttgt caattttagt
     6901 aagtggataa attcattttt ggttagtggt tgacgaatta agttctgttc gataaacggt
     6961 atatcatgga cgataagcca acgttttgcg cgtcttgaag acgagcagcc agaacctgta
     7021 tacaatttaa tcatcataca ttcctccaat agctaagtat ttatgaaata ataacatgaa
     7081 gaaatagtcg aaaagtgcca tttagaggtg taaaataaga aaatgttgtc acgtataatg
     7141 gaactagcta gataagaaat actattaaat caagaaaaaa gaaagaaggc acaagtatgt
     7201 caaacacagc cgacgcaata gtagtgatcg atttacaaaa aggggtatgt tttgattctt
     7261 cgccgataca cgaattagaa acagtgacag cattagtgaa taaaagaatc aaaacatacg
     7321 aaacgattgg gaaaccagtt attttcgttc aacacgaaga tgctcaatta gtgccacaaa
     7381 caaaaccatg ggagctattg tcggaattat ctattcctga gcacagttat tttgtgagaa
     7441 aaacccatgc gaattcattt tataagacta atttgagtgt tttattaact gaattggact
     7501 gtcattcgat cgaattatgt ggggcacaag cagagtattg tatagatacg actgtgaagt
     7561 ttgctcatgg attaggatac cagcttatga tgtgtagagg agcaacgaca acttatgata
     7621 atccttttat gaaagcaaag gaaacaatcg ctttttacga gaaaatttgg gataaacgat
     7681 ttctgacatt tttggagcaa taagttgttt cttcgtttaa aaaaagcaga atggatactg
     7741 gtttatccat tctgctttat tacgtaaaat gagaaaataa tcctgttcta tttttatggg
     7801 ataaaccatt tattttttgt ataaaaaatg tttgcgttta catataattc tcctagaaac
     7861 ataaaaagga gtgaatagct tgagaacaaa acaagtatta aagggagcgt tggtcatctt
     7921 atttgctgta agtacaagcg tcccgcaatg gacagtatat ggagagagca tttcttccga
     7981 atcggaatct cgggaggtag aaaccacaga aactactgat gctggaaatg aaacgaaatc
     8041 gagtacttca caaacagaaa caaatactga aacaacggtt gagacatctg ttactagcac
     8101 agatcaagaa acgaccgcta ccacagataa ccaacaaaca gaagaagcaa cagctacaaa
     8161 aatgtcaaac gacgaatcct cttctgctaa agtaagtgac aaagagaatg ggacagaaaa
     8221 tgatgatatc ggtaaaggtg aaaatttcaa tggtaaagaa tatttgaatt acttcggtaa
     8281 acagatgaca gaaatactta atggaccaac agaagacatc aagtcaaaat taatagagtt
     8341 attagtcact gagcttgctg ttaatgatta tggtgtagat aaagagatta tcaaacatct
     8401 gattgctact tatctattgt acgatatcgc ttttgcaaaa aacagtgtgt tgatgtcgat
     8461 gcttggaggt acagatgatg ggacaacgcc tacagaaaac acaggcttct atccaaatac
     8521 aaaacaactt catcaaactg tactaaacaa acaagatggc aaaatgatgg atgtatatgc
     8581 atattatgtc gatcaaggtt cagataaaac agtcatgatc catggcggat ttcgagggaa
     8641 ttggaataac gggatcgtta cagaagaata caatgatttt tataaggccg ggtataattt
     8701 attatttgtt gattccagag cgactggtaa tagcggaggc gattatgtga cctatggaca
     8761 atatgagtca gatgacgtcc tttactggat aaatcaagaa gttcgagagc ggccatctca
     8821 aaagatttta ctttatggtg gttcgatggg agcagctacg atgatgtctg tattagcgaa
     8881 agatattcct gtcaatgtca aaggaattat tgaaaattgc ggatttgcat caattgatga
     8941 acaactacgt tttacgtaca gccagacagt agcccccgca ctaccggatg ccataaaaaa
     9001 tcagttagac atcattgggg atcaagagca tgaagattta tttatgggcc ttttgaaaca
     9061 atactatttt gatcaggaga tgcatttgga tacaaaagct gctctaccta cgattggaat
     9121 gtcagattca ttgcctaaat tgattatcca tggaacagca gatgatgtag tacctgtgtc
     9181 taacgcgcaa aaattatatg agttatcagg agggtataaa gatcttttat tagtagaagg
     9241 agcagggcat ggaaaggcac aggaagttga ccatgctgcc tacacgaaac atgtaacgga
     9301 ctttttgaaa gtagtgttcc atgatcagat aaacgtaaag tatgtggatg aaaacaataa
     9361 aagtctactc aaagaccagg acgaaatcca gctttacgga gcttatggag aaaattatat
     9421 gacagagcaa aagacattcg aaggatacga attagcaaat gttgaaggac cgactgaagg
     9481 gatttttaat gagacgatac caactattat tttctattac aaaaaaatcc cagtagctcc
     9541 accaaaaaag caagatccga cagagaatgc agacaataag ggaaagaatg aacctcgaga
     9601 ggatcaatca agtgatgata cgcaaccgat tcagatgaca gtgaaagtac aaaaaaagac
     9661 agatgcaaaa aaaagaatgt tgccgaaaac tggagaaaag aaacattcgc ttctcattta
     9721 ttcaggtgga tttttatctg ttagcacgat tatcacatgg atttggcgaa gaaagagagg
     9781 gtaaatgaat gaaatggttc aagcgaatag tgattgcagt accagttatc atcgtagtta
     9841 ttttagtcac tgtatttttg attaatcaaa tcacaccaaa gccgattagc ttgcttgtta
     9901 gaaaacaatt tgacacaagt gaaaaagaac aagtatatgc ccgaccagat gatttccagc
     9961 aaaaaatcga acaaatcgat ataaaaaaag aaatatccta tccttcaaag tacaaaaata
    10021 ataatatgga tatctacaca ccgaaagtgg aaaagaaaaa attaccgatt cttttctgga
    10081 tgcatggagg cgcatatgta ggaggggata aaaatgattg tcgtgattat ttggaatatc
    10141 tatgttcaga cacgcagcaa atcatcgtaa atatagatta tgaacgatca ccggaagcaa
    10201 aacatcctac accagttatc caattgaacg aagccattca agcagctaaa aaagagataa
    10261 aagatcaagc agattggtcg aatatttcga ttggtggaaa ttcggcaggt gcacaaatta
    10321 gtggagaata tttgttagca cttcaaaatg aagaaattaa aaaagctgat catcttgatc
    10381 cgactttgga gaacaagcag attacgaagt ttatttcttt gtctggtctg ttggatcctt
    10441 ctgcacttac tcaagtaagt gataaaatct ctagctttct ttatgaaaaa tgtggatggg
    10501 cttactttga taataaggac tttgaacaat cagagaaggt caaaagttta gccttggtca
    10561 gacatgcgga tcgttggacg caaaacacat tcttaacgga tggaaataca aatacgttta
    10621 cgaaacaaat ggaagaagta acttctgtat ttgagaaagc gggggtgaaa gtcacaaaag
    10681 tagattatgc ggagaaaaat gctgttttga accatgaata tcagtttgat ttcagcaata
    10741 aacaagcgca agaaacatat caaaagttag taatgttttt caaggagtaa agtcttatga
    10801 tgcaaaagag gttgtaatct gtcacttagc tccaagtcac aaggagcaat ttcaataaac
    10861 aagcttttca tggtttatga atattgtaac ttgtgactga ggagttagag atggcaaggg
    10921 gcacctttta ttcgaaattt gggaatatca cacgattatt gtcacgatct cttttacgta
    10981 aattttataa gtcagatttg ttgttttgat cgtttaaaaa aagcaacaaa tccgaagcct
    11041 gcggaggcaa gaagggacaa aaagccgagt ggtaagcaaa agaatgctgg ttccactaat
    11101 attccgttgt tattgatata aggctgggaa caaagatgaa tagcaaataa aatcaatgca
    11161 ctagcgaaaa aaagcaaaga aatatggata gctttcataa gcagcacctc cttttttata
    11221 attgtatgat aaatagatta agaatctata aatgtgacaa gtttgttagg atgtgaataa
    11281 aatgatcatc tagcgaactt gaaacaaaga tggctaatga taagcaatta atgattcagc
    11341 aatcagatag gtacaaagtt taccatcata cgtctagacc aataatagaa aatatgggaa
    11401 tataatagaa aagatttagg atacccccaa aagaatttcc ccaaaaattc gatgtatcct
    11461 aaactttttt attttacata acaatcatat caactgtgaa ataaaattac aaatgataac
    11521 ctaaaatgag gccaaaagcc agtgttatca aggaaatact taattcacca aaattttttt
    11581 taatttttta gaaaataaga aacaaaaata ataaaaaaaa gaaaagataa attttttact
    11641 actgtatact aactttgtta tcgcatctaa caagtaactc gaataatacc aatacaacct
    11701 tctccaaaga tgcgatgaca tacgttctaa cccaccgact attgatgttc tgtaccaccc
    11761 ttgcagaacc aaaaaagcca ctaccaaata tttggtagtg gctttttttg ttttatggat
    11821 ttttcgcttt ttctgttatg gtgctattct ttgatttcag aaatagtatg tcgaacttta
    11881 gcgatagaac gacgtgattc tttttcgttg taaaacatca aaatcacata tagagagtcc
    11941 aaaatgctta gttgagaaat acgggaagct aaagcttcag atcggaattc tgtttcttca
    12001 gaaatagaaa taaaaacgac atcgccaagt ttagcaaggg aagaattagc ttggctagta
    12061 ataacgattg tttttgctcc agtttttctt acggtttcag caatatggat tgtttctttt
    12121 gattgccctg tgtgagaaat caaaacagca cagtcttttt ccgtcaataa agaagcttcc
    12181 atcaattgaa tatggtaatc cgtgctgtga gaagttgcga taggggaacg caaaaattta
    12241 tgataagcgt cagttgctac aatctctgaa ccgccaacac cgaaaaaata gacacgttta
    12301 gattcattga taatagtagc cgcttttttt agatcctttt gttgtaacaa cttttttgtg
    12361 tcatttaaag ttgaaatact agactcgaac accttttgcg ccatagtgag ctcagtatct
    12421 gttttctgaa tattttcgtg gatagaaata gcagatagat cattttcttg gatcaacatg
    12481 gccattttaa aatctttaaa tccattataa ccaagttttt ttgtaaattg aaaaaaagta
    12541 gagtcagcaa tgcccagttc acttgctaaa ttgctaatag gactatgact tactttgctt
    12601 ggattttcta aaatataatc ggcgatagcc tgttcttttg ggctgaagtc gttgtacatt
    12661 gttttgattt gtagtcttat ggagacgctc atgagaattc ctcattttca taataagatt
    12721 atcatttttt ccgttctcat taatgttaaa gatacaagga gagtaggaaa aaatcaaaca
    12781 aaaaatattt ttgtaaaatc tatttacaaa aaaatttttt tgtataatga gggtataaga
    12841 aatggaggcg ctatcatgga aattggtgta attggtttgg gaaaaatggg attgaattta
    12901 gctttaaact taaaagagca ccatcacaaa gtacaaggac tcgacatttc aagtacagct
    12961 gttagtcagg caagagaaaa tgacattcct gcttatcaag agatctctga atttctagct
    13021 acttttgagc agaaaaaaat catctggtta atgcttcctg ctggagagat aaccgaaaac
    13081 atgttaagaa aactttttcc aaaactcgga ccaggagaca ttattattga aggcggaaac
    13141 tcttattata aagattcaat ccgtcgagca gaagagtttc agaaaaatga aatcggttac
    13201 ttggattgtg ggacttctgg aggaatcgaa ggagcacgac atcaagcctg cttaatgatt
    13261 ggaggagata aagaaacttt tctatccgtg gaacaattat tcaaagatgt agcaattgaa
    13321 agaggatatc tgtatgctgg tgcatccgga agcggacact tcttgaaaat gatccataat
    13381 ggaatcgaat atggaatgat gcaagcaatc ggtgaaggat tccaacttgt acaaaaaagt
    13441 gagtatgctt ttgacttgga acaagtcgca cgtgtttgga atcatggttc ggtgattcgc
    13501 ggctggctga tggaaatcat ggaagatcag ttaaacgaac atcccaattt aagtaattat
    13561 cggggaatcg tttctgcatc aggtgaagca aaatggacgg ttgaaacagc gctagaaatg
    13621 gctgttccag ttccagtaat tgcaactagt ttgttcatga ggaatctttc acaggaagaa
    13681 gatagttttt cagcaaaagt agtttcagca ctaagaaatg ggtttggcgg acatgaaata
    13741 gttgaaaagg gtgagtaaaa tgccagatta tcatatagca atcgttaatt ccagcagttt
    13801 cggaagagtc tttccacacc acttggaaag attaaagtca gttggagacg ttcatttctt
    13861 tactgttgat caagagattc caggaaaaga actagcggag ttacttaaag gattcaatat
    13921 cattattgca agtgttacgc cattttttcg acgagatttt tttgaaaaca aagatgaact
    13981 gctattgatt tcccgacatg gtattggtta caacaatatt gatttaaaag cagcaaaaga
    14041 acaccagaca atcgtatcta tcatacctgc tttagttgaa cgaaatgctg tagcagaaaa
    14101 taatataact aatttgttgt ccatgcttcg acgcacgaca caagcacaag caagagtcaa
    14161 ggacgatcga tgggaagatc gggcggagtt cgtcggtagg acgctgttta acaaaacagt
    14221 tggtgtgatt ggtgcaggaa ataccggaag cggagtaatc gaaattttgc gtaacggttt
    14281 tcgctgtgat gttctagctt atgatcctta caaatcagat ttatacatcg aaagctttgg
    14341 tgcaaaaaaa gtagaacttc aagaattact ggaacaatca gatatcattt gtttatgtgc
    14401 gaatttgaca gaagagaact atcacatgat ttctgataaa gaagtcgatc agatgaaaga
    14461 aaatgtttat ctatctaata gtgcaagagg cgctctagtt gatgaagaag cgatgattaa
    14521 tggtctgaaa agcggaaaga tcgcaggata tgccacagat gttttagaag aagaaccggg
    14581 acgtcaagat catccgtatt tagcgtttga acaagtagtg attacgccac atatatcggc
    14641 ctacacaagg gaatgtttag aagcaatggg tgaaaaatgt gtcagagatg tcgaacagat
    14701 cagtcagcac cttcttcctg aacgttctgt ccagacaaag agcaactata taaaaggatg
    14761 atgaagaaaa tggtgaacgg tttaaaagtg aaaacaggcc ctcaatttta tttatatgaa
    14821 gaaggtggta tttcaaaagt ttctgatctc ttgaaatcat acggcgcgaa aagagtactg
    14881 gtcacccacg gaacggtatc atgggaaaag gcgctaccta aattagtatt tttgaatgac
    14941 gaaacgattc aattttttta tcatcgttat tctggagaat gtagttatgc tgaagccaga
    15001 cgaatagcta caatcatcaa aaaaatgaaa tcgatttcgt agttggcgtt ggcggaggaa
    15061 aactgaccga tctagtgggt tatagtgcca atcttgcaag aatcgatttc ggagtcatcc
    15121 ctactttagc tagtaattgt gctccatgga cacctcttgc tgtcatgtat aaggagaatg
    15181 gacaagcaga agggaaaaca gaacactttt acagacaagc tgcttttttt ataacagatc
    15241 cccaattagt gattgattcc cctgttccat atttcattgc cgggttagca gatacactag
    15301 caaaatggta tgaatctgag ctcatcttag aacaagattt tttgcaagat gaatcatttt
    15361 tgaagctagc acaagatact gcgaagatct gcaaagaaga gattttgaat cattctgcta
    15421 aagcaatcca agatatggca caaagaaaac tgacatcgga gttcaaacag ctttcagaga
    15481 ttatctttgc tgttgctggt ttagttggag gattaggaga taaatacgca agaaatgtgg
    15541 cagcacatgc tatgcatgac gctatcagta aatatattcc ggaaagccat cgttttctac
    15601 atggagaaaa agtagcgtat gggattttct atcaactggc actagaaggt cgctgggaaa
    15661 aaatagacga gttatatcct ttgtatcggg aattagaact gccggtttct ctagaacaaa
    15721 tgggattatt tccgaaagat aaacagataa tagataaaat ggctgaattt attgattcga
    15781 aagagaaagt gcatttgatt cctatagagg taacacagaa atcactgata cagtcaatga
    15841 tggaactgga aggttatatc agaaagatct gaaggaggag gacacatgga aacattaagt
    15901 gtagtacaaa gtttgttgat tgctttatgg gtagccgcgg ttatgtcccg ctggttaggt
    15961 ggaggagcca cgttgacctt acgtttttct cctttgatga ctggattagt cgtcgggttg
    16021 atcatggggg aagttgcaca agcgatgatt gttacagccg ctttgcaaat gatttatatg
    16081 ggggtttttt ctccaggagg atcaatgcca gctgaaccat ctattgcagc agctatcgca
    16141 gtaccagtcg cattattagg ggatctgtcg ccagaagcag cgattgccgt tgcggtgcca
    16201 gtcggattgc tcggaagtta cttgtatcag tttcgttttt tcatcaatac ttttttaggt
    16261 aaatatacag acaaagctgt agaagatttg aatacaaaag ctatggcccg atcaattatt
    16321 ctttatccaa cggttgcctc atttttatta ttcgttccgc ttgttttcat tgctttatat
    16381 ttaggggcgc cattgatcgc tgatgtaatc aaagctttag agggaacagt cgttatccac
    16441 attcttgaag tagtaggtgg agggttagcg gcaatcggta tcgcgacaac tgtatacgtt
    16501 atcggtcgaa aagattatct ggtctttttc ttccttgctt attttatgag tgttgttttg
    16561 aaatctttag atattacgat ggttacttat gccatttttg ggattattat cgctttgatc
    16621 tttgtccagt cgcaaaaagg gaaacaagta cagcctgcca caagcaataa caattcagca
    16681 tcttttgatg acgaagatga ctatgatgac ggattttaat ttaggaggaa tgggaaatgg
    16741 ctgaaataat ggataatcaa acaggtgctc ctgaagaaat cacgaaaaaa gatgtaacaa
    16801 aagcctatct gagatggcat tttgcaaacg aaattcctca ctcttttgaa cgttacttgg
    16861 cgccatcact actatacgga atgatgccaa tcttgaaaaa actttataaa gatgaagact
    16921 ctttaaaagc agcatataaa cggcagttac tgttcttcaa cactcaatta agctggggtg
    16981 gcggtgtgat tactggccta atgtcttcta tggaacagca aagagcagaa gaagagtatg
    17041 aagaaaaaga gatcttgatg caggatgact tgatgtataa cacgaaagcg ggattgatgg
    17101 gggcactagc aggaatcgga gatgcaatcg attcaggaac cgtccaatat atttttatcg
    17161 caatcgcggt accttgggca caacagggaa gtcctttagg cgcacttttt ccttttatct
    17221 gctttgggtt gtatcaggtt ttactagggg tatttttcgc aagacaagct ttcactatgg
    17281 gccgtaatgc tacaggccta aagcaaaaca ctggtgttca gacagcgatt gaaatgctat
    17341 cagttttagg gttgtttatg atgggggtgc ttgcgggaaa ctatgtaaaa gtagaatctt
    17401 cattgaaatt tgcgatatcc ggacgtgagt ttgttatcca ggaaattctt gatcaaatcg
    17461 tgccagggat attaccttta gctgtcgtaa tgggtgtgta cttgttctat acgaaaaaag
    17521 gattgaaagt cacacaagca ttattatggc tgactggaat attaattgtg ctagcaggaa
    17581 tcggtatttt ataaaaagaa gggaacgtga ataagatggg tgtagtcaat ttagcgcgtg
    17641 tggatgagcg tttgatccat gggcaagtaa tggtaacgtt atctcaaaaa agtggagtga
    17701 attccatttt tgttgtagac gaagttgtag caaaagataa atttatgaga gatctttaca
    17761 aaaatgcagg aagccgtaca ggacaaaaaa caattgtcat tacaccagag aaagctaaat
    17821 tctattggga tgaatatcaa tttaaagaat acaattgtat tttgatcgca aaaacagtcc
    17881 aaacgattta cgacttagta aaacacggaa tccccatgga agaattgaat attggaggga
    17941 ttgctcaaaa aaatcctgat acagatcttt tagtgacgaa atctgtttat ttaaataaat
    18001 cagatgctga aaaattgaaa gaaatgaatg aacaatatgg cgtaaagaat atttattttc
    18061 aagccactcc atctgcacct aaaacaggat taaaagatgt attgaacaag tttgatttgt
    18121 cataaacaaa tgcttagaaa aaagataaag agggcgaaaa aatgaagaag aacgagctgt
    18181 ttcgtgattg ggaatttcgt tatcgctata tttaccgtaa gcgccgtaca aaaaagagta
    18241 aacagcgttt tctttcagca ttagtatcag atatttacag tatgagaaca gatgtgacag
    18301 tcattgctta cgatacgcta gcctaccgat caaaaaatat ttatgttgga gatatcgaaa
    18361 aagcagagaa agttatctgt acttattacg atacacccgt tcatgcatta ggaagttatt
    18421 tcatgtttga ttggaaagac caaaggaaaa aaacaatcta ctctatatta ttgtccttca
    18481 ttttgttgtt cagtttaggt tggtggggaa tgatgatata taacaaaaat cctcatcacg
    18541 tattcgatct gctatccgta taaacaggta tcactgtact agcatttggg agctactttt
    18601 tcttattggg aaaagcagct cgcggatggc ctagcagaca aacttttatt cgaaatactt
    18661 catccatatt aacgatgcta gaaatgatcc gtacgattga tgatccgagt gtagcgtatg
    18721 cgtttgttga tgaaggctgt tatggagaaa agggcttaga cagcgtgaga tcgggtatga
    18781 aaaaagaggc tattcttttt tatctagact ctgttggggc agatacaccg ctacagtttt
    18841 cgggaaatta tttttcaaat aaagaacagt ggctgaaaca agttgataag ttgaaagaaa
    18901 aaaacgtcaa ttatattttt agtgcaagaa aaaagcaagc gcagttcttc tatttgacca
    18961 aaacagattt acgagggaaa acatttaatt ggcaaaatgc caatcagatt attgctcttt
    19021 ttcgataagt aaaaagtgca aaacaaggag tgagaagact aatgttggaa atcatgatcg
    19081 ttacacatgg taagttgagc gaaggactga aagatgcggc ggaagtaatt gtcgggacat
    19141 cgagccatat tgaaacaatg tgcttagagt ctggggagga catccaaaca ttcggagaga
    19201 aggtcaaaga aaaattaact atgatcaaca cagcagaacc catgctagta tttgttgatc
    19261 taattagcgc aagtccgtac aatcaagcgc tcttggcagt caatgaactg actgaagaaa
    19321 agaaagcagc cacttatgtc atagggggcg tgaatctgcc aatgttgtta gaagcaatca
    19381 atcatcagat gcttcacaca ccgatagaag aagcggtgga acaaattgtc aaacaaggaa
    19441 aagataattt aactgtttgg catgcttcag cggaagaaaa aaaattagat gaggacgatt
    19501 tttagaagga aggctgaaaa gatgaagtgg ggatttagat ggtatggtga aaaaggggat
    19561 tcgatcccat taaaatatgt tcgccaaata ccgggaataa atgggataat tggaactttg
    19621 ctgactaaaa tgcctggaga tgtttgggag atttcagaaa ttgaggagtt gaaagcatct
    19681 gttgagagcc aaggactgga actgcttgga attgaaagtg tagcgatcca cgatgcaatc
    19741 aaggcaggga cagatgaacg agattactat attgataact atatacgaac aatcaaaaac
    19801 ttgtctcgat gtggggttcg attgatttgt tatagcttca aaccaatttt tggatgggcg
    19861 aaaactgatt tgtttaatga aaacaacgat ggaagctatt ctcttttata cgatcagaaa
    19921 atcgtcgatc agatggagcc aggagaaatg tatcaattga tacacagcca gtcaaaggga
    19981 ttcaaattgc cgggttggga agaagaacgg ttgaaaaaat tcgctcagct ggaaaaactg
    20041 tatgaaggaa tgaccgaaga agaattattt gaaaatctga cttatttttt agaaaaagtg
    20101 attccagtgt gcgaaaaagc agatgtaaaa atggctatcc atccagatga tccgccatgg
    20161 gaactttttg gttttcctag agtgacgaaa aatcttggcg acttgaagaa aattctaaat
    20221 gcagtagatt ctccatataa tggactaacg ctgtgcacag gatctttagg ggcaaatccg
    20281 gaaaacgatt tagttgaaat catccatgag gtaggttcgc gcatccattt tgtccacttc
    20341 agaaacgtgg agtttttagg agaaagaaag ttcaaagaaa cggcacatcc ctctacagaa
    20401 ggctcccttg atatgtatca tattatgaaa gcgttggtgc aagaagggtt cgacggtcct
    20461 atacgccctg atcatggtag aaccgtgtgg ggtgaagtgg ctatgcctgg atatggcctg
    20521 tatgatcgtg caatgggact cacttacatg caaggtctat atgaggcgat aagtaaggaa
    20581 aaaccactgg gagagcatta tgaataaaat caagctcttc atctttgata tggatggcct
    20641 tttattagaa actggacgtt tagcttatcg tgcttatgta aaatcagcac aaaagtatga
    20701 ttatgaaatg cgtaaggaag tctattattt actaactggc caaacagaaa tggcgataag
    20761 agaacaaatg ggcattttgt acggagaaga tgttccatat atcaaatggc gagaagcaat
    20821 caatcaatat aaagaaaaaa tcgtgaaaga agataagaga gtatatacga aaaaaggagc
    20881 agaagaaatt ttatcttttg caaaagaaag aggaatccat acaatcgtgg cttcgtctaa
    20941 tacacgggta aaagtagaaa tgtatttaaa aatggaaaat ctatatgcct tgtttgatca
    21001 aatcatttca ggggatgatg taaaaaaagg aaagccggaa ccagagatct ttttgaaagc
    21061 ttgttcaaaa atgaatattc ctccaagtga agcacttgta tttgaagact cgattgcagg
    21121 gatcgaagca gcaaggcgag cgggcatttt gtcttttctc atcaaagatc atttgatagg
    21181 gttgcccgat cataatggga agcataagtt gaaagtagat gtaagtttat atgaatccaa
    21241 taaagcagac tatgaatttt atgacctgca tcaagcaaaa cgatttttag aaagtaaagg
    21301 gttgtatctc taataaagag gactattttc tagtcctctt tatttattgt cctgcacgac
    21361 tgagggaaca gatgaaaaag aagtaatttt ttattttgaa gtatctacct tatttgtagt
    21421 gaacaattta gaacaaacac aaaacgcatc tactgttatc taccagtaga tgcgtttaaa
    21481 gagaagaacg agaatcgtcc atatgagggt ttccactcct tatgcagatt tttttaattc
    21541 ttgcactgct tgttcgatcg taacacctgt cgctacatga ttggtatttt ctttgtcaaa
    21601 aacgacaaat agattcaaat ctgtatccaa ggttactcga tattgtatat ctttgttata
    21661 gaatgtcata gccattctcc tttctttaaa tacttgctga aaggcaacga acgcgttgat
    21721 aacgaaattc catttataag tataccacca attgaaaggt tttcatagtt aagaaatttt
    21781 aaagtcaaaa gttgcagata aaagcaaata aacaagaaaa caaaaagtga atcaatcgcg
    21841 gttattcaac tttttcttcg attcgaagac aatagaagac aatgaatttt atatttcatt
    21901 gcattatcct tgtgttatta gaaaaagcat gatatattaa atgagtaatc tattttgaaa
    21961 cgtaatttga gcgatatatc tacatagata aaactccttt tgcctatcaa atatttattg
    22021 caacgaaaaa acgtacattg atacgtatca ggaggaattt atttatgaat aacggtacag
    22081 taaaatggtt caacgcagac aaaggttttg gctttatcac tggtgaagat ggaaatgatg
    22141 tatttgcaca tttttcagct atccaaggtg acggcttcaa aactttagaa gaaggccaag
    22201 cagtgtctta cgatgttgaa gatggtcaac gtggccctca agcaacaaac attgttaaag
    22261 cttaataaaa attgactttt aaccgtcttt tcgaaagaaa a
//
LOCUS       DADQDV010000050        22216 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.050, whole genome shotgun sequence.
ACCESSION   DADQDV010000050 DADQDV010000000
VERSION     DADQDV010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22216)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22216)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22216
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.050"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(103..621)
                     /locus_tag="J8S10_001946"
     CDS             complement(103..621)
                     /locus_tag="J8S10_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HAZ9630529.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(623..1240)
                     /locus_tag="J8S10_001947"
     CDS             complement(623..1240)
                     /locus_tag="J8S10_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HAZ9630530.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(1237..2091)
                     /locus_tag="J8S10_001948"
     CDS             complement(1237..2091)
                     /locus_tag="J8S10_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAZ9630531.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(2088..2999)
                     /locus_tag="J8S10_001949"
     CDS             complement(2088..2999)
                     /locus_tag="J8S10_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAZ9630532.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(3040..4374)
                     /locus_tag="J8S10_001950"
     CDS             complement(3040..4374)
                     /locus_tag="J8S10_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAZ9630533.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            4582..5412
                     /locus_tag="J8S10_001951"
     CDS             4582..5412
                     /locus_tag="J8S10_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HAZ9630534.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(5656..5905)
                     /locus_tag="J8S10_001952"
                     /pseudo
     CDS             complement(5656..5905)
                     /locus_tag="J8S10_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6096..6290)
                     /locus_tag="J8S10_001953"
     CDS             complement(6096..6290)
                     /locus_tag="J8S10_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630535.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(6795..6980)
                     /locus_tag="J8S10_001954"
     CDS             complement(6795..6980)
                     /locus_tag="J8S10_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630536.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(7830..8171)
                     /locus_tag="J8S10_001955"
     CDS             complement(7830..8171)
                     /locus_tag="J8S10_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAZ9630537.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(8171..8401)
                     /locus_tag="J8S10_001956"
     CDS             complement(8171..8401)
                     /locus_tag="J8S10_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016178973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAZ9630538.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            8688..9026
                     /locus_tag="J8S10_001957"
     CDS             8688..9026
                     /locus_tag="J8S10_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630539.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(9231..9470)
                     /locus_tag="J8S10_001958"
     CDS             complement(9231..9470)
                     /locus_tag="J8S10_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase"
                     /protein_id="HAZ9630540.1"
                     /translation="MFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRM
                     PLVLTEEQIEPWVTDISFARKIITQQMPELVMEKV"
     gene            complement(9446..9793)
                     /locus_tag="J8S10_001959"
     CDS             complement(9446..9793)
                     /locus_tag="J8S10_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF159 family protein"
                     /protein_id="HAZ9630541.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGM
                     KKKTNLCFQIRKK"
     gene            complement(10525..11106)
                     /locus_tag="J8S10_001960"
     CDS             complement(10525..11106)
                     /locus_tag="J8S10_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAZ9630542.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(11289..11915)
                     /locus_tag="J8S10_001961"
     CDS             complement(11289..11915)
                     /locus_tag="J8S10_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAZ9630543.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(11937..13268)
                     /locus_tag="J8S10_001962"
     CDS             complement(11937..13268)
                     /locus_tag="J8S10_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HAZ9630544.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(13423..13824)
                     /locus_tag="J8S10_001963"
     CDS             complement(13423..13824)
                     /locus_tag="J8S10_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HAZ9630545.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(13910..14116)
                     /locus_tag="J8S10_001964"
     CDS             complement(13910..14116)
                     /locus_tag="J8S10_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630546.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(14211..15713)
                     /locus_tag="J8S10_001965"
     CDS             complement(14211..15713)
                     /locus_tag="J8S10_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HAZ9630547.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(15731..16186)
                     /gene="argR"
                     /locus_tag="J8S10_001966"
     CDS             complement(15731..16186)
                     /gene="argR"
                     /locus_tag="J8S10_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HAZ9630548.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(16284..16901)
                     /locus_tag="J8S10_001967"
     CDS             complement(16284..16901)
                     /locus_tag="J8S10_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630549.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            17122..18495
                     /locus_tag="J8S10_001968"
     CDS             17122..18495
                     /locus_tag="J8S10_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAZ9630550.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLFLSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            18570..19682
                     /locus_tag="J8S10_001969"
     CDS             18570..19682
                     /locus_tag="J8S10_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HAZ9630551.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(19754..21391)
                     /locus_tag="J8S10_001970"
     CDS             complement(19754..21391)
                     /locus_tag="J8S10_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HAZ9630552.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(21559..22167)
                     /locus_tag="J8S10_001971"
     CDS             complement(21559..22167)
                     /locus_tag="J8S10_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAZ9630553.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
BASE COUNT         6475 a         4531 c         3873 g         7337 t
ORIGIN      
        1 aagttattaa gacaaatgaa taaacaacta cgctttcctc gaaacaaaaa aataaagcac
       61 aaatgcgcat ttacgcactc atgctttatt cgtacaatta attcagataa cggcagcgca
      121 taggatgcca ataacacttc ctaaaatagc tcctcctaaa atgtcagtag gataatgtaa
      181 aagtaaaaaa atcctcgaat aagcgatcaa acaagcaaat aaaaaggcta atattcctgc
      241 aactggactt aattcgaaca acgcagctac tgataaaaag gctagcgctg tatgtcctga
      301 aggaaaagaa gaagtcttcg gtttacttgt gtaaaggaca agccgacgat ttttttcata
      361 aggtcttttc cgtcttgtcg tttttttgat aaaaagcaaa ccaacaaaaa aatagatcaa
      421 actgccgata agaatggcta gaccatattc tctagtatca ggtatcaaga ctaaaacagc
      481 agcaaggagc aaccaaataa aaccaccatt agagatatta ctgataaatt tcaaaaaatt
      541 gatttttcga ctatccgttt tccgttgctt ggcgaacttg ttgataatac tatcatcgat
      601 tttagcaatc aaacgcaaca tgttattcct cctttttaag aaccttttct tgcgtacgat
      661 ggataaaaag caggacttga aaataaaaca agaaactgaa acctaataaa gcaaaataga
      721 ttggtcctgc aaaccagaat gcgacaagaa ggatcaacgt gcctgccaaa tagaaaagcg
      781 cgcttttgaa atcattaaaa aacaagaaaa atgcagtaat ccaagaagct tctttttgtt
      841 ccagttgaag caagattttg taactaaaga gaagcgcgct taatagaagc aaaaacaacg
      901 tagtatacat caatgtatag ccaattcccc caccccaata gcggaaaatc tgataatcga
      961 tcaatagaag aagaaaataa acacttgcta aactatcttg ctttccataa agagagaagt
     1021 tctcacgaaa ctttttccag aatagtgaac cgagcttttt ctcttcattt tttttgtaat
     1081 gataaatcat atacagaact gttcgacttg cagttcctaa tgtgaaaaca ggcaagacgc
     1141 acaggaacca tagtagctgt aaatggataa gacgtggaat ccattcaatg atttctaaga
     1201 aataatcatt ggctttttta ccaatcgatc gattcatcat ccttttgaac ctcctgtcaa
     1261 atccatccct tcaatgaaat aacgttgtgc aaaaaagaac agcaaaatcg tcgggatcaa
     1321 gacaagtgtt gctcctgcca tcagataatt ccattgtgtc gttgcttggt tctgaaaaac
     1381 ttgcaagcca atctgtaacg tgtatttttc ttgatcttgg atatataaca gaggacctaa
     1441 gaaatcattc caagctgcgt tgaaggaatt gatcgcaatg gtaatcaagg caggtttcgt
     1501 caatggaagc atcaaatgac tccaaatata caaatgattc gctccgtcga tttcagcagc
     1561 ttcgatcaat tcattattga tcgataagta aaattgacgc atcagaaata tattgaacgc
     1621 attgccgaag aacgatggaa cgatcagggg caaataagta cctacccagc cgatcttgga
     1681 gaataataca tattgaggga tcatcgttac aaaccccggg atcatcatcg tagaaagaac
     1741 caaagcaaac atcagctttt tcccaggaaa atcaagcttc gcaaatccat aagcaataaa
     1801 agaatttgaa aggacattac cgatcactac tagcacagtg atgaataatg tatttcttgc
     1861 atagcgccaa aaaggaaagg cggcaatcgt atccagatag ttttcccata cgattttttc
     1921 tgggaaaaag gtcggaggat aacgaacgat ttcttccatt ggtttcaatg aagtaaacac
     1981 catccaaagc aatggaatga tcaaaatgat tcctattact gtcatgagga cataacttag
     2041 tatttttttt gtttgccgat tcacactggt ctttttgaaa taatccatca tttgccgtca
     2101 cctccagaat aatagaccca cttaggtgca agcttcaaat tgacaaacgt cagaaccaac
     2161 acgatcagaa acaggatcat tgacatagcc atcgcataac ccatatcaaa agctacgaac
     2221 gccttgttcc acatatgcag attataaaaa agcaaagaat ttgcaggtcc gcctgttcca
     2281 tttttcgtca tgacataagc ttcttgaaaa atttggaaag aaccgatcgt agaggtgatc
     2341 acatcgtaaa aaataatagg agtgattaat ggcaaagtaa tacttttgaa ctttccccaa
     2401 acgcctgctc catcgatttc tgctgattca tataaagatc taggaacatt ttgtaatgta
     2461 gctaagtaaa gtagcattgc tcctccagaa ctccatattt tcatcaaaat caacgcaggt
     2521 ttcgtccatt gtggatcaaa cagccaagct ggtccaggga tatggaacca gcccagaaat
     2581 gtgttgatca atcctgcaga tggagaaagc agctgcatcc ataagatgta gactgctact
     2641 cctgataaga ctgccggtaa atagaaagct gtacggaata cactgattcc tttgattttt
     2701 tgattgagta ctgtggctaa aaacacactg aaaatcgtcg tcagcggtac attgaagatg
     2761 acgaaataaa cggtgttgta taacgatttc caaaataaat catcgtgaac gaacattctt
     2821 ttgaaatttg ctagaccaat gaaattcatc ttggatgtca aattataatc ggtgaaacta
     2881 ccaataactg aaaaaagcat aggccctagc ataaatacca agaacccgat aataaaaggc
     2941 gagataaata aataggccca tcttgcttct tttttctttc ggatagataa acgcttcaaa
     3001 ttttcttgcc tcctctgtac ctagacagtc aaaaatggat tattgatttt gcttgactaa
     3061 gttttctact gctttttgtg catctgccaa tccttctttt ggtgattttg ttcctaaaag
     3121 aatctggtca atctgttcat tcactaatgt cgtgtaatcc ggagcatcta aaggaactgg
     3181 tgtgatcacc gtatttttaa agttttcgtc cgccatttga tagatcattt ttcctttatc
     3241 cgttaggttg tcattattca ctaaattctc attggctgtc ttgctcgcca tgatatcaaa
     3301 acttttttcg ccgaattttt cttgtacttc tggagaagaa agatatttga tgaattcata
     3361 agaggcctca ggatcttttg ctccgtatgg tacttccaag acgaatccgc caccccacga
     3421 ccaatggcct gaaccttctt ctttttctgg gagctgcatc acgccaaaat caaaatcatc
     3481 cggtgcattt tccatcaaac tagagtaata attgatattt tgggcacgca tggctactaa
     3541 tccggaaata aatggatcag atacaccaga cccaaattcg gcttctaatt tattgatcgt
     3601 atttttccca taataatctt gccagtcttg gatccactcc aaggcttcca ctttattttt
     3661 agtatcaatc ttgacttttt catctttgtc aaaccaacta gtcccgttat ctgcgtttag
     3721 cgcccataca tcagccccta aattccataa tggataaaaa ccgatgcgtg taaattcttt
     3781 tccttctttt ttatctagtt tacgtgctgt ttcttctaat tcatcccaag ttgtcggtag
     3841 atcttgttca ctgattccag cttctttaaa taacttttta ttataaaaaa tgacttgtgt
     3901 atctgtattg aatgggatcg cataaggatc accttcatat tctactgtat cccaaagctg
     3961 cggataaaaa tccttagaag tgtctttttc tacatatttg gagagattag ttgcttgctg
     4021 tgcttctgct ctttgggcaa cggaatttat gtcctgtaca ataacatcgg gtgcatttcc
     4081 agctgttatt gcagataaag atttagtcca gatgtcaccc catggctgat acttataatt
     4141 tacatggatc tcgttttgtg attgattgaa atcctcaatg atttcttcga tagcttcttt
     4201 tcgtgcaccg gatccccaaa aggaccagaa atcaatattt tttcttccat cacttgtttt
     4261 ttcagaagaa tttgctgcac ttgaactggc atcgcttgca ttacttgatc cgcatcctcc
     4321 taataaaaac aatgctgaac ttgccagcaa ccctgtaaac aataattttt tcatatttta
     4381 cctccaaatt ttaatgtaac cgatgccggt tttaatataa cgatatcatt ttgttctgaa
     4441 aataacaatt tataaggtat gattctaaaa aaattattaa tgataccaat actttatata
     4501 attcgcgagc gctttctttg aattttttaa tctttcgtag cagaatgaga atgtattaaa
     4561 aatagattag gaggaatttt gatgtttaga caccagaaag aattgcagtt tgaagcaaaa
     4621 ccagatcgtc cgaatccatt aatcgcgaaa tatctgcagg agctgatcgg cggccaatat
     4681 ggcgagatga gtgtagctat gcagtacctg ttccaaggct ggagctgccg aggagaagaa
     4741 aaatataaag atatgctgat ggacattgca acagaagaaa tcggccacgt ggaaatgttg
     4801 gcgacaatgg ttgctcgttt attagagggt gcgcctgttg aagatcaaga agcagcgatg
     4861 caaaaagatc caacaatcgg tgccattatc tctggaatga atccacagca cgcgatcgta
     4921 gctggcttag gacctcgtcc tgctgacagc gtgggcaatc catggagcgg tgcctatatc
     4981 attgcgagtg gcaacttgtt agcagacttt agagctaatt taaatgccga atcacaagga
     5041 agacttcaag tagcacgtat ttacgaaatg atcgatgatc gtggcgtaaa agatatgctg
     5101 tctgttctcc ttgcaagaga tagctatcat caaaatctat gggaatgtgc agtgaaagaa
     5161 ttagaagaaa aagaaggttc aatcttagtc ccaagtactt tcccgcgtga caaagaacga
     5221 aaagacattg cttatgactt ctataacttc tcagagggag accaaagtag tgaaggttct
     5281 tgggctagtg gcaaagcact ggatggcgaa ggcgaatatc aatggttgaa agaacctaag
     5341 atcgaaggcg ctgcaccaaa attagaacca gtaacaccaa aaatgtatgg gacacctcca
     5401 ttcaagaaat aaatatctac ccgtagaaac acccgttttt tgttccacac gctttgtgag
     5461 caaaactgac taaagtcatt aatcataacc acccttcaaa agggtggttt tctctagagc
     5521 tataagctca aatcaccggc cagcgcctaa agacgctggc tttcatattt tatgttcaag
     5581 ccatattgcc tttgccagtt ttgcccacct cttaaaaggt ttatgtacta ctccttagcc
     5641 cttaaaagga tcgtcttact ctcgtacact cagcttatct aacgcactat catgtttttc
     5701 ttgttcttga atgtactttt tgatggtcgc ttcattttgt cctacttttg tcacatagta
     5761 tccttccacc caaaagtgtc gatacccaaa tttatatttt agatttgcac aatctcttga
     5821 tgatctcctg aatattggct cgatattgat tataaattat ttttcttcta tactttggtg
     5881 tgaatacaat gtggtattta cacatctact ttgtacgggc taaactattt ccctttattg
     5941 ctccacccgc atagcaagtg gttttgtatt tcaatcgctc ggcgcgctca attaggtcta
     6001 aagacaataa atctaaaaac ccgctgcttc actgacagaa acaacgggtt ttcagaaaaa
     6061 aatgaaatga aaaagatctc ttacggcaat ctattttatt tttttgattt tttataaatg
     6121 gaaaatgctt caagaagtcc aagaaataaa gccgtataaa aacaagaacc tatgaaatct
     6181 ttatttatta gatattcaac agaaatcccg ataacactag ccaacaatat atttatcaga
     6241 agtgtaaaat aaggatgctt tttatagaat agaactagtg ttgttttcat agactctcct
     6301 ttcttcatat ttccaattaa tcacaaattc acggcattac tagaaaaatt aaaggggcgc
     6361 agaagtggaa aaatactctt cgactttccc tacaaaccag gccatcttgt gtttaataac
     6421 tataccaaat ctaaggtacc tctaaatcta aattccattt gtggcggtga cctccaattt
     6481 ttaactcttc tatctcccat ccagtataca taaccttgat acttcgacca cttatatatc
     6541 gaacacacaa atacctatcc attgcaggag tactacctaa cttagttgct acttgcatct
     6601 aaataacagc tgaaaagata ggacttactc ttagtaaagt atctgaacta ttaattttta
     6661 aactatcatt tttatcctca actacatgca catctgttgc aacttcactt tctgtctcat
     6721 ccagataaat gattaaggaa tcgggaattg caatatcttc agctgacgct ggaatagttg
     6781 agctaaatta gtcatcatat ctttattata aaataaccaa cagcaaaaaa tacaatgaaa
     6841 aacaaacttg gaactaatgt atcattaata aatgttgaaa aattcagcaa ctcattactg
     6901 tatgatttta gcagcccaac caacatatac cctataaaag ctaataagat ggttaggaat
     6961 cctttagaat ttttactcat tcatagacac ttccttaaat aacttttatt atagaaggta
     7021 ttgtaaataa taatattgac aaaaagtgac tcaaaataaa aaaaacctta cattatactg
     7081 gaatgaactg tattgatagt gtacctaaaa gctctactga cataagatcg tgtaatcggt
     7141 aaagtaattt tattaattat acgggatgta atcaattaga gaataaacta atcataaaag
     7201 gtacttttac attcataatt gtcgctttga gattctactt tggttcacta tctgacccaa
     7261 ttgcacattt tcgatcatta caagtattgg tgtcgttaga acaactaaat aaaaactagc
     7321 ggtagatttt tcagaatcta tgctaatttc tgtatggatg ttccagtgat ggcaaatttc
     7381 tcttttcatt gtttttcttg tcgcatgata tgcctttttg tgttattcag ttaaactata
     7441 gaaattcttt cctagacaga tcttgatccc aaattttacg tttttgagca tcgatatagt
     7501 ttaaaatgac attactcata tctaaagagt ttagattttt taggactaaa actgtcagtt
     7561 gttctttttc ttctttctgt taaagtattg tcgcgacttt tcgtatacgt taagatatgt
     7621 cgtgaaaaaa caagttttgt gacacaaaaa aacgaatgac ttgaggaaat cacctcaatc
     7681 attcgtttaa aatgctatat attctttagt ttaagatacg gaaattaatg ccatcgacca
     7741 cactagtaga atgaacgaca tttacttggc ctttttttaa tttcgttatg tttagcatat
     7801 aaaaatatta tagagtttac ttacaatgct taaaacatat actgtataat ctgatcaatt
     7861 ttagccatgt cttgcaatgg taagttttct atttttttga gttttcgttc cttaaaatca
     7921 agagatttta attgtgtaat aattacttgt ccttttatat ctagctcttc aggtaatgag
     7981 taacgtgtcg gtaaattctt tatagtggaa gtaattggac atatgaccga aaacattgtt
     8041 ttacggttaa attcataacg agagacgact agtcctggtc gtcttttttg aatttctttt
     8101 cctacggagg gatcaaaatc aatccataca atatcacctt ttttaggaat ataaattctt
     8161 tcttctgaca ctataaaatt tctctccctt caggagttaa atcttcccat tcgtctttct
     8221 cataatactc ggcctcttcc ccaccactaa atggatcttc aatttttgga actaacgtaa
     8281 ttgttccatc atcagaatac acaacgatat attcttggtt ttctgaaggt ttctttccgt
     8341 tatcagaagg taaagttacc actacagaac ttccttgtaa tctagatttt gtaacaagca
     8401 ttatcatcac tcccttaata aaagtatact atataacact aagtaacgca aaattcccct
     8461 ttgtaaacta tctagaaaat tgttttgttt aaagtatatc ttattggata taaatagaaa
     8521 taaattgtag ccagttcatt ttttctttaa ctaaaaaaat aatccaagaa acattgaacc
     8581 tatggatcca aaagctaccc aaatactata gctaaccccc cgctaccttc aattttgcag
     8641 ataaaacgct ttgggagaaa atttcaaaga caacaggcca tcctatcatg cccgattata
     8701 aacaaaaagc tggctattcc ttttgctctg acaaatttca attgggaaag ttcacgaaac
     8761 tagcaggtga agaagtttca actgttcgga tcaaagaatg cccgcttcaa atagaaacat
     8821 tggttcaacg aatttcaact agacaagact ttgctattgt agaacgtgag atcgtagcta
     8881 tttttgtaga agaagggatt ttacatgatc caactcatat caatgtggat aaatggcaac
     8941 ctcttatcta taaattcaga gaatatacaa ctgccaacca gtcgttaact ttgaatttta
     9001 gattccaaga attcaaagag tcataatgat aaacatcgtt aggtataaat aaaaaagact
     9061 cgcagcacga gtaaaaaaca aatagaagct atacattaga aaggtcgact gtgaccctat
     9121 agatgcagta tatgcagctt atgagcattt cttctgttct ctttgttttt gggatctgtg
     9181 ctgaagtctt tttcgttttt tgccgctctt tctttgaaaa atcgattatg ttataccttc
     9241 tccattacta attcaggcat ctgctgagta atgatttttc gcgcaaaaga aatatctgtt
     9301 acccaaggtt cgatttgttc ttcagtcaag acaagcggca ttcggtcatg gattggtgcg
     9361 actgtgcggt taggttcagt agtcattatg attgattctg ccattttttc atcctgatgg
     9421 ctacgataaa aaccgccaat atacactatt ttttccttat ttgaaaacat aaatttgtct
     9481 ttttcttcat tccactcatt gggaaaacac aacgattttg caaaaatggt tgatgaaagg
     9541 tctttttttc ttctactgtc tctgcacggg cattaatcat caattgtcct tttttaaatc
     9601 cggtaaatcc ccacttcatg atttccggag tgaggatgtt ttcttcctct tttcttaacg
     9661 tcacaacaag atttgacgga aaaacttctc cagctgctaa ttctgctgcc tgcttcggtt
     9721 gtttcgtctg ggcttctcga taataattct gaaggagctc tgactctaga tcaaaaaaat
     9781 aacgaccaca catcctaatc cctcccaatc tttttttcta tcatacactg caacaagaag
     9841 ttcgcaccaa caaaacgctt tcaatttttg tagaactaaa aaagttgtga caagtgacaa
     9901 actctccagt gaatggtatt ctcctgccaa ctcctcggtc acaagtcaca atattcaaca
     9961 aacatgagaa gctgcttttt gaaattgttc cttgtgactc ggagtgaaac ggcaggctta
    10021 cgacctctgg gtaaacggtg ttcaaaagcc agtttctcgg tattaagcca aatttatgca
    10081 aaaatgtaga aagctatttt cacaaaattt ttcttaatac tcgaaactaa gcgacttttt
    10141 cacaacctct tccttaaacg gtgttcaaaa gcttgcatct gcggtaataa gcccaaccaa
    10201 acgaaaaata tgagcagcta tttttatttg gctgttctta ttacttgatg cagggcagct
    10261 ttttcacaac ctctccacta aacggtgttc aatcagctaa ccttcggtat tagctcaaaa
    10321 aacggcaaaa tatgaggaac tattttgccg tttgtttctc taatactcag gtcaaagcgc
    10381 tgatttcaca acctctaata cacggtgttc cagaagtagc ttcttcgaaa aataagccga
    10441 aatttcacaa aaatttgaga agcaattttc gtaaattcct tcttatttct tgaagctgac
    10501 cacttctgtc acaacctcta attattaaag aaccttttgc gaagttaaca atctttcttt
    10561 gatcaattga aaattctgcc taagtagtga tagatcctgt gtgactttca acaataagat
    10621 acttccctgg atttcagcaa tcaacgcttt ggcttgacgg tctgcttctt catcggacag
    10681 tttttcttca gaaagtgcca ggatattttg tttcgtatac ttgacccatt gattgactaa
    10741 ttctagtagc aacagacggt attcttcatc cactgtactc aactcaataa tcaaattacc
    10801 tacaggacag ccatgataag tgatctgtgt ctcatgatca gcgaaaatcc agtccaacat
    10861 ttcttctaat gcttcttctg gctgttttcc agcatttaag atgtcttcga acaattctgt
    10921 ctgccatacg tccatatgcg catggatcac cgctagacaa acttcttttt ttgaagaaaa
    10981 gtaataataa aattgacctt ttcctgtatc agaagctgct agaatatctc ggattgacgt
    11041 ttcatgatag ccttttttat aaataagatc tttggtcgct tccaagatct tttcctttgt
    11101 tttcaatgat attctccttt ttcatttctc atagtcctat attatacagt aaattcatca
    11161 ttttttcttc ttaatcgttt aaaaaagact gtgccaaatt atctgacaca gccctcacta
    11221 taaaactgtt ctcatatagc tagatgttca ttgattcaag aactgcgagg acaaaagcaa
    11281 ttcctatctt atgatagttg ctctaatact tcctctgttg tcatcacttg atctgcaata
    11341 aagccaaagt tcgtcaacgc tgcatccatt gcttcttggc caggagcacc aattgcatct
    11401 gtcgctacca caacattgaa tccactctct accaattcac gcatatggga atcgctacac
    11461 aagtttccgt tcattccacc aagaattact gtgtcgattc cattttttct caattggagc
    11521 gccaaatcat tgctttctgg tccaaagatt ttatgaggag agctgatgat cgtattttca
    11581 tccaaataag gtttcaattc ttcgataaaa tcggctcctg aaccttcttc cactgattca
    11641 tattgacttt ttctagcaaa catctgctgc tcaagcatca tatgttctcc tgcaccgcca
    11701 aattgccatt tatggtcatg tgggtaaaaa taatgaggag aaataaagag tttgtatcct
    11761 ttttcttttg cttgttttac catttcaatc atattttcga tcgtattgta tttttctaag
    11821 atatcttttg tcaaaccaaa gccaccgcct gctggtttca agaactcgac ttgcgggtca
    11881 gtgagaacta ctgctgtatt tttattattg aacatggtgg attctccatt cgttatttat
    11941 tttaatacat catttagagc ttcactcatt gtcggatgag aatagatttg atctctcaat
    12001 aacgtataag gaagttttcc attcatagct agcgaaatca agttgatgac ttcatgagaa
    12061 tcttccgcat agatacttgc ccctagaatc aagtcagttt cagggtcgac taaaactttg
    12121 aatacacctt taggatcttc taatacttgt gctttaggga caccgcttgt catatacttg
    12181 aataatttgt aattgacgcc ttgtgctttg gcttgttttt ctgttaaacc tacattggat
    12241 aaagtcggag tgataaatac actgtaaggc acagctttcc ggttattcgt tgttcgttta
    12301 ttctcgccct tcaactgatc cataatgatt cgataatcat ctagagagat ataagtgaac
    12361 tgcaatccgc ctttgacgtc tccaatcgcc caaatgttgt ctgcatctgt acgaaggtat
    12421 tcatccacag cgattgctcc gcgatctgtt agtttaacat ctgtattttc taatccaagt
    12481 gatgctgtac ttggttttct tccagttgca gccaaaactt ttgacgcttg gattgttact
    12541 tcttggccat cttctgtaaa ggtgacggca gctgttgatt cttggtctgc tacttgatct
    12601 acagatacac ctagatggaa ttcgattccc gcatttgtca tgtcttctaa aatcatttgc
    12661 gcgatatctt catcttcacg tggaagaaat tcagaatggg catcaagaac gacaacttta
    12721 gatccgtatt cattgaacat tgatgcaaat tccaagccaa tatatccagc cccgatgatc
    12781 actaattttt ccggtaattg ttcctgatcc atcgcttgcg tagaatcaat caagtagcga
    12841 cttgtattca atcctttgat tggtaaaatg attggttcag aaccagtatt gatgaaaatc
    12901 cgttcgcctt caacaatcac tttttcacca ttattcgtca cttcgatttg atggttagaa
    12961 agaaaacgtg ctgtaccgtc catcactgtc ccagttgcct catcgctgat catatgataa
    13021 tttttggcgc gaagcatgcc cgtcaatttt tctttccgag caacagcctc tgtaaagtcg
    13081 attcctcttt ctccattgaa aatcaatgat ttagaaggaa tacagccgat gttgatacat
    13141 gttccgccat acatacgtgt tgacttttca acgactaaaa ccgattcacc ttttgaagct
    13201 aacgccttcg ctaaagtctt accgcccttt ccaaaaccga tcacaatatt ttgatatttt
    13261 tccatcattt ttccctcgct tcttttttac ctaccgattg gtacaaaaat atgataaccg
    13321 ataattgtct attctccaaa tcatctgctt tatttgtcaa aaaaaaccag acaaaaagcg
    13381 gtcctttcac gtttttagtc tggttcgatt tcctttattc ttctaaacaa tcgttacttc
    13441 tacatcgata tttcctctag ttgctttgga gtaagggcag aattcatgcg catcttctgc
    13501 aattttttgg gcttcttctt cgctgatgcc atcgatatgc acttctaata ctacaccgat
    13561 ctgatagccg ccatcatcta aattataaag agagacacgt gcttttactg tggactctgc
    13621 tgtcattcct gcttctttga tcatatgttg taccgcccca ttgaaacaag aagcataacc
    13681 tgctgcaaat aattgttctg gatttgttcc ttctgcatgg attcctggag gagtgatttt
    13741 catatgcatc gagccatttg gtgcctcgac ttctccattg cgcccgccat ggttgatcat
    13801 tgctgtttcg tatgcttttt tcattgtact gctcctttcg attgaccatt tgctacttgg
    13861 ctataattat agtgtatgac aagtaaggcg ctttctacaa aaattctgct tattcgaata
    13921 ccagaatgcc gtcttctact atttttccaa aaaacaaaaa aatactactc gtgaacaaca
    13981 gcgtcatatt tgttccaaaa taaatagcaa tcttttctac ataatctttt atatgattga
    14041 ttttaagata catatatacc agaaagttga ccccataaac caatactgtt aaaaaaataa
    14101 ccatattcgt taccattttt tcctcctttt gctggtctcc ctaccagcac tcgatttaac
    14161 cataccactt tttttgccgt ccaagcaact agcctttcaa aaagactggt ttattctgct
    14221 gttaatgatt caagatcaga aaaatgtccg aataattttg ctaattttac taacgccaac
    14281 ttgttctttc cgaattcatc attttctatc tgtaatacta gtaacggctc atgtaagctt
    14341 aaacggatca aaaaccagcc gtttccgtat ggctcttcta gatcatatcg aataccttct
    14401 tcattttccg ggtcgaagtt catccctttt tcttcttcca acagtcgctt catttcttct
    14461 aatatcttgt ttccttgttc gcgtggttca tcgctgaaca attttaatcg gatttcttgt
    14521 acttctacgg gctgtttcaa ctctttgatt tgttcatcta atgtgatacc ttttcttttt
    14581 aattctggca aaagcatcag gatctttgcg atgacatatg caccatcatc cagaaaatag
    14641 ttttccttga atgcagcgtg tccgcttgtt tcgatggcta gctgtgtatc tttcccaaga
    14701 cggttaagtt ctaatgcttt attgattaca tttcgatagc cggaaatata acgaacttgg
    14761 atgcctcctt tttcttcaat gaatctttgt agatgagaag aagtagggga attcgtcacg
    14821 attcttgttc ctggatgctc ttttaatacg attgtactta atactgcgat caaattattt
    14881 cgattgatca ctgttccaga agcactgaca actgcagaac gatccacatc tgtatcgaaa
    14941 atgatcccaa gatctgcttc atttgctaaa acagcctgct tgatactttc catcgcttct
    15001 ttattatcag gatttgggat atgattagga aatcggccat ctggttccaa aaattgggaa
    15061 cctgttgaat ccgcacctaa gctattcaat actttttcag caaagaatcc accagcacca
    15121 tttccggcat caacaatgat tttccaacca tttagtggtt tgctttctag tgttccaatc
    15181 ccctttttaa tttttgtgac taaatcttgc gcataaggtg tcaaaaggtc tgctttttct
    15241 acgcttccag tttgttcgct ttttattttt tgctgctgtg ataggataaa agcaatatct
    15301 tctttttctg ctcctccttc tgaggtaaag aattttattc cattataata atagggaaga
    15361 tggctagcag tcagcataac cgcagcatcg cacgagaact gttcaaattg agtggacata
    15421 aacatagcag gcgtagtagc taattcgaaa tcgatgacat gtatcccttg ttctttcaga
    15481 ctttggatca acgcctcttt cagtgctggt ccgcttatcc tactgtcatg accaatccca
    15541 atcgtccatt ttttatttgg atcggttgat ttcttctttt tctttatcca gtttgctagt
    15601 ccccagccga tcttttttac catgtctgtc gtcaagttta cttcatatcc ttcaactggt
    15661 aatgcgattc ctcgaatatc cgatccattt tgcagcgctt tcatatcttt catataaaag
    15721 tcctcctcat ttattccctc attttttcca gcttttctgc aaatcgctgt gcttcttctt
    15781 ctgagcggca aataataatg aatgtatcta caccggccat cgttccgaca acttcagggt
    15841 aagccacttc atctagccaa ttcgttacca catcggcacc atttcgttca gtcaatacga
    15901 taaccatgaa ctgaacagac tggatacgca aaacctcgcg tctaattgct gtacgcaaac
    15961 gttcttcatt taaagaaaca gatggctggt taaataatgt atagcgtact attttgtttt
    16021 cattttgact ttttactaac ttcatttctc gaatgtctcg agaaatcgtt gcttgagtca
    16081 catcggcgcc tgcttcatgc agccgcgcaa gcagctcttc ctgtgtccca ataggttgtt
    16141 ctgtaatgat ctggcggatc agtgcttgtc gctgtttctt tttcatatta gacacctctc
    16201 aatgttgatt atagcaaaag ataagtaata tttcttcata ttttggtatt ttttactttt
    16261 attttttgtt ttcattcagg ttgctaacct ttttctattt taacacgcaa aatcgtcttc
    16321 attttttcag gtgctgattt tcttggatcg ctgatgtaaa tctctttgtg ttctttagaa
    16381 gctctttcat agccttcttt tgcgatgaat gcttctaatt tctcaaacgt tgctggttct
    16441 tcggcatagg gcccgacgtg taagatttgg gcacaaagac cttcttccat ctttttgaat
    16501 actacttgtt ctttcaagtc ttccggaagt ttgctagaac gctgaatggc ttcttgtgct
    16561 atcgcttctg taacaaagtc aggctgtcgg atcatcaatt gataagaaaa atgttctttt
    16621 ttcatcactg gttcatgcaa atacttttct tgcagtcccc attgtccttc cagtggatag
    16681 acagtataca tctgataatc aggaatcagc caattttttt taggcgacat gcgtattgca
    16741 tagctgactg catatagaca ggctactctt cgtttaaagt cttcctgatt cgggtcgccg
    16801 atccctctga tgctaaagaa tgatttttta ggaacctcta gtatttgcgg gctttttttc
    16861 atactatagc tcttgtcttt acgccattca attttttcca tttttcttcc tccgcgaaat
    16921 tccatttagt tatttattat catacctctt tttgagtgac ttggctaatc gtgttgacac
    16981 tatttttcag tttgtgctag aataagtgaa gtaaataaat cgtacagata acacgtttcg
    17041 gcgtgtcgag agagaggcgg tttctatttt tataatagaa atcactctct ttttttacga
    17101 aattttttag aggtgatgta aatgacaaaa caaaaacagc tgcttttagt acctgcagta
    17161 attgcaacag ggatgatgtc ttttgcgggc gtattgatcg agacggccat gaatgtaact
    17221 ttcccaactc ttatcagaca gtttgattta acgactgcac aagtccaatg ggtaacaacg
    17281 atttatcttt tgatgatttc gatcattgtt ccgctgtcta cttatttgaa tcgcaatttt
    17341 agtctcaaaa aactcttttt agcttcaaat ctgcttttct tggcaggtat aatgatcgat
    17401 ttcttctctc ctaccttcat ggtcctattg tttggtcgat tgctccaagg tgcagcgaca
    17461 ggtatcgctc ttccgttgat gttccatatt atcttgacat ttgcccccct caatcgacga
    17521 ggcgcgatga tgggtgtcgg tactttgaca acggccattg ctccagcaat tggccccact
    17581 tatggaggca ttatgacttc acattttaca tggaatcata tcttcctgtt tcttgtgccc
    17641 gttttgtttc tttctttgat tatcggctgg tttgctattc ccgagatggc agtacaaaaa
    17701 agtggttatt tggattggat aagcgtttta ggaatttgtc ttttgtttag tggaagtcta
    17761 acatttttga gtacgttggg aacagtttcc agctggattg ctttaatcat cggcggtatt
    17821 ggctggttcc ttttttacta tcgaagtaaa aaagtggagc atccactgat ccgactgtct
    17881 attctttcaa ataaaacatt ccgcttgttt ttgattggct tcttagttta tcagttttta
    17941 ttacttggtg tatcttttgt cttgccgaat ttccttcaga tcgttcaagg aagtagtcct
    18001 tttgtcgctg gattagcgat gcttcccggc gcagcggttg gtgctttgct ttctcctttt
    18061 tccgggaaaa tgctggatca atatggtccg aagaagccaa tttttgctgg gctgattctt
    18121 tctttgattg gttggctagc attattccta ctcataggac acgcttcagt gggtgtattg
    18181 attgcttgtc atgtgtttta tatgatcggt atcggattat cttacagcaa tatgatgacc
    18241 accggaatga atgcactgaa tgaagaacta caaggagacg ggaacgcaat gttcaatacc
    18301 ttgcagcagt tttctggcgc tgtggctact tcattagtag cggtcattat caattacgtc
    18361 cagcatcata cttcccataa ctatgaagtg tctactacat taggatcaaa agcagcatta
    18421 ggcgtcttgt tgctgttgct tctcgtaagc tttgctcgat tcgcctatta tctgttcttt
    18481 gctaaaaaag cgtagattcc atatacggca ggtgttgcat ctgccgtttt tttgtgtgaa
    18541 aatggttgtt tgtaaaagga ggctttttta tggaaaaaat tgccattatc ggtggcggga
    18601 tcattggtat gaccctagcc agttacttag atacatcaaa attcaatgtt gctttatttg
    18661 atgaagggac aggacaggca actaaagcta gcgctgggat tatctcccct tggttgtcga
    18721 aacgcagaaa caaacaatgg tatcgtctgg ctaaagacgg cgctgctttt ttccctaaac
    18781 ttataaaaga tttccaactt gatcaaacga tttacgcaca atcagggaca cttttgcttc
    18841 gacctgaaaa agatttagct gaattggctg ttcttgccga gaaacgaaaa gaagaagcgc
    18901 cagaaattgg aaacatcgaa tggctttcac ctgaacagac atctcaagca cttccgttat
    18961 tgaaaccagc agtttcactg cgtatcagtg gtggtggtcg tctggatgga aaagcatatt
    19021 tagaacatct tggtcagcgt ttagcacaaa aacaaatgga gcagatccag gcaaaagtca
    19081 ctttgcataa gaagagcgat tcttggctca tcaagggacc gtttggagaa tacacagctg
    19141 atcgtgtaat tttgacacct ggcccggcac ttaagccttt attacaagaa ttaggctatg
    19201 ctgcagatat acgtccgcaa aaagggcagc tcttagcatt tcagacatct tataagatga
    19261 gtcaagactg gcctgttgct atgcttgacg gagaagctga tttcattcct ttcatggatg
    19321 gaaagatcct tttaggtgct acccatgaaa acgatcaagg ctgggatttg gctcctacta
    19381 gcgaagctta taagggattg actaagagta cagaacagtt cttgactgat ccagatcaga
    19441 taaaaaactg gccatacgag ttccgtgtag gtacccgtgc ttatacgtca gatttttccc
    19501 catttttcgg cgtactgcca gatgatccaa gcttactggc tgctagcggt ctaggctctt
    19561 ctggcttgac cacaggtcct tatatcggct atctattagc caacttctta aatactggtc
    19621 attggcctac ggaagattat caaaaggaca tctccaccta tattacgaaa aatccatcat
    19681 agaaaaacag ctttttcaag taaggatccc gagcgatatt gcgcatggat tacttcttga
    19741 aaaagctgtt attttagttc aatttctgaa tcaaattctc caaactttct tttgcttcat
    19801 ctggcaagag atcttttcct atctgagctt caatgaatcg taaacgaata tcaagtcgtt
    19861 gtttcaccag atttttatag gacgtatcct caaaagaaac aggaaaatct ggtataggta
    19921 aatagtggat gtcttcaaat ggaccaaacg acttgaattc tgccgtttgt tgcacgattc
    19981 tttcaacgat tgacaatgtc gtttcaggtt tgattttttt atcatcgaaa tatccagtat
    20041 tcaggacata gcaggctgtt tgctgtttca aaaacaactc tcgaaaagct tgatagtctt
    20101 ccctaagagg atagacacgg aaaggattag caaatggttc aatgactagc tcatctagct
    20161 gtctttttgt agtgatattt tccgcgtctg atcgttttgt tgctaatgtt gcaccaaaag
    20221 acgctgctaa aactgggtca ttgatcttga taattggcgg aagcgaatca tctttcatga
    20281 tccaaaaaac agcatcgatc ttttcgctaa gatgatcgac tcggtcgggt gtcgcataac
    20341 gtgatttgac tgtccgccca tttccgtttc gtatatctcc tgttactagg actttttctc
    20401 ctttacttgt acatgtcacg cccacattct gacaagtaag gaaagaagaa atggccggat
    20461 catcagacgg atagtcttgt gttttatcaa agtaagaagg ttccaaggca gtagcaaaac
    20521 cattttttcg agaaataacg aaagcatcgt catgcaagat cgaaacagag tgaccttccg
    20581 tatgttttgc taaggtaatc gttgattttc cagaaccgga caacccaaat acagccatcg
    20641 tataggtctg gtcattacta gcatattgtt tcatcccacc gtggcaggca ataaagccat
    20701 tgcgatttcc caatgcccaa gcaagcgtca aagtcgcttt ttttaattct ccaaagtaac
    20761 gtaatcctag cacagccgct gtattatgga gagcatcaaa caaaatgagt ccatttggaa
    20821 atgtttcatg tgtccattcg ggatcacaaa agatataaag atctccctca tcaaaggaaa
    20881 cagacttttg ataagtctct aagatcttcg aattcgctgg ctgaaaattc agcaaataag
    20941 aatacaaatt gttctcaaat ccttctggaa tcagcaaatg actttgcaca gaaaattctt
    21001 cagataggcc aacgattact tttgtatggt aaaactggcg cttgcgactt tgatacacag
    21061 cttctcttaa aattttctcg tatttgcttt gttccttgtc taagtcctca aagatccgcc
    21121 gagcacttgc tgttcttccc acaatgcttc catcattgaa tactagtgtc ctaacatcag
    21181 ctggtaaatc tagttcttca gcatgtgaga ttgttaaatc tgtgatgatc gttcctggac
    21241 tcccttttgc tagttgataa gctgtcttcc tatcaaaaac ttcatgaaca ttattaccgt
    21301 aaaatgtcgt ttctacaatc gatcgaatac tggataacag tggatttcca cttgtgattt
    21361 cgtttaattc gagactctct tttgtactca tggctcctcc tcattcccta aacaaaaaaa
    21421 cgttttcttt attatacatt attcgagttt ttatttgtac tgctgcgctg tgggaagcaa
    21481 acgagttatt tttcacacaa aaaaaccgag aacttgaata aacaagtttc tcggtttcat
    21541 cattttcctt ttatcggctt agtaccagcc gtttgctaac cagaatgttt tagcagcatc
    21601 ccatgaacca taacgagatg ttacatattg ttctgctaca cgttcttgat tggcagctga
    21661 atagtcgccg tttaagtatg aagcatctaa ttgataacgg ccgatgtaac gtccgttagt
    21721 agctgtgtat gaaccgcctg attctttttg tgcgatccat tcttttgcag agcttgaagt
    21781 tggcgctgtt gcagcagctg gggcagcagg agctacttca actgtttcaa caggtgcaac
    21841 gtatgtatgt tcttgcgttg ctgtttcagt tgtagatgct gtattttctg ttgttttgtt
    21901 ttctgttgtt gctgaagaat catttgaagt tgggattgtt aattgttcac caacataaat
    21961 gcggttgatg tttgcgatcg aatttttttc agcaattgca tcgatcattg agttgtctcc
    22021 tgcaaatttt tgtgagatct tagataatga atcacctgat tttactgtat aaacttcatc
    22081 agcgtgagca tttgtagttc ctacaaacat tgcagtagca ccagcagcaa aagttgtacc
    22141 taaaacaatt ttcttaaatg aattcatatt aaactccttt ttttctccgt tttttattct
    22201 ttcgacgcta ttaact
//
LOCUS       DADQDV010000051        22210 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.051, whole genome shotgun sequence.
ACCESSION   DADQDV010000051 DADQDV010000000
VERSION     DADQDV010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22210)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22210)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22210
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.051"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            99..284
                     /locus_tag="J8S10_001972"
     CDS             99..284
                     /locus_tag="J8S10_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HAZ9630554.1"
                     /translation="MPKTAREIVKILKSNGFKKTGQTGSHAKFYNSKTKRTVVVPIHN
                     GDVPLGTEANIWKQAGL"
     gene            351..746
                     /locus_tag="J8S10_001973"
     CDS             351..746
                     /locus_tag="J8S10_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin HicB"
                     /protein_id="HAZ9630555.1"
                     /translation="MKTKNIFYPAIFEKEGEAYNIVFPDLPEISTFGNSLEEAYLNAK
                     DALGLALYSVPDAEFPKPSAVEELTLKANQVVVIIQLNIKLFRRSLNTKTIRKNVSVP
                     EWLVLLGKEKNINFSQLLQKALEEELLEK"
     gene            736..1113
                     /locus_tag="J8S10_001974"
     CDS             736..1113
                     /locus_tag="J8S10_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630556.1"
                     /translation="MKSKKETEPMKATHLNYFSRTLINNLLKDTTGISVSTKHFANDL
                     IIFEDNNLRIEMFIEQATPNSIPEFCYTHTEKMKHAKSVKDVEALSESLTNALNLVKK
                     AKLLFEFQTDYHNELLAQSEILD"
     gene            1114..1509
                     /locus_tag="J8S10_001975"
     CDS             1114..1509
                     /locus_tag="J8S10_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630557.1"
                     /translation="MKQEKRKMKQTQTETVNDTLADQLAGYYKLFEMGKAQRLIHYLW
                     KYKILFLFWESTLTFSVLFYKSDFYNQHLVLGSFLLIYTILMLNLYTYITLEEHLVIS
                     DAGIERNIKRVSFKITLNKPTDKKLSEAF"
     gene            complement(1816..2214)
                     /locus_tag="J8S10_001976"
     CDS             complement(1816..2214)
                     /locus_tag="J8S10_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin HicB"
                     /protein_id="HAZ9630558.1"
                     /translation="MKYFFCAVFEWKGNEYAVKFPDFPDLYTHGETLEDAFEMAQEVL
                     EGYLVLLELQEKEIPSPTPVQELNARIKRSENVNLFVVKANTKVAKARNKQNYDRKSV
                     TVEHYLNVLAAEENINLSKALNDLLREKLI"
     gene            complement(2406..3173)
                     /locus_tag="J8S10_001977"
     CDS             complement(2406..3173)
                     /locus_tag="J8S10_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HAZ9630559.1"
                     /translation="MKKDELTKYNEEFLATIDMKMDLKSYELYQLLFSYISPTKLKKT
                     GVVDLPVKAIINYMDVDQNLETELKTIVNTLQRQAVYEISNLDKKYKTYTTVSAIDRI
                     HWDLEEHSVSFSFSEDVIPLIVSIKKKYPFFVFEDLASFQKKYSIVLYKYLAMYYKKY
                     LIAKNKGDFEKAEIYKNPLIEIVKIREITKTENEYKTISNFDRRVLRESVEEINEKSM
                     LNIDFAKVRKGRNYNFAVQFNISSEFDEKTYREKKLG"
     gene            complement(3208..4431)
                     /locus_tag="J8S10_001978"
     CDS             complement(3208..4431)
                     /locus_tag="J8S10_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HAZ9630560.1"
                     /translation="MESYQFQVFKLVPSLERRGNRMKITEKNVNPKFETTESNLKKFD
                     LTVTLSNQLVDSIVEMDAMPQKIYLYAIGHLDPKNPPFNNTVKVSKKALFALMSSSSS
                     SSKHSRLKQVIEKLHQQSVIKIQRTKPNGKTEYKVISPLEITEFNDFSDAVSIKFSSS
                     IMPLLTNLENHFTQYTFDQVVNLTSKYAISFFQLFTKDFNLYEANRDNLTWSTKSLDR
                     LKNPVFSIADLRKKFSIEKKYKAFRDFERRVIKEPIAQLNKYTDFKIDYELIKKGHTY
                     TNIKFLLTRTMSVPVPYKQEQRDPAYLKGAEDKTEKMNQSYLKAMNSKYTKLLIKNFL
                     ISSADLCDLKLMSRLQNKVYPLYDRLSKDRGFESVVNHLSYVATHKEDYTIKNTVKYL
                     EKSITSYLPYVNLYD"
     gene            5412..6215
                     /locus_tag="J8S10_001979"
     CDS             5412..6215
                     /locus_tag="J8S10_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HAZ9630561.1"
                     /translation="MSQEVTEKIIDSDVDLVSEQTNAIVRYNNGLNTTALRGFKPVEM
                     DVFWAILSKMKRQGTAEVTFDFNLFRYLVKYDRREKDSFYSVLKDLSDKLGNLTYRFE
                     DSDVYEQLWLFQKFRIDKQKETVTIKANEEFEFILNSIGKNFTRFELDNFTKLRSSYT
                     KELYRHLMQYRNKEWRNGYWVVKVEDFRRALSIPSSYRMTNIDKRILEQAKEEFLAPD
                     ENGIQVFETFDYEKIYAKKGRRVDRLRFTFSEPESNLPTISMHNWLEED"
     gene            6800..7255
                     /locus_tag="J8S10_001980"
     CDS             6800..7255
                     /locus_tag="J8S10_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630562.1"
                     /translation="MNAINWHEFVNYMESLLDDLKSFSIADAVKHGLPVSTTMKLRGL
                     KIPDEIIKLRTKTIIETAKVVDNMNHELKGKKTTYEKDFERFLKSVIGKYLGKKSFSE
                     LRDEEIVPTPMVSKIRKNKAEGNYYLGTIAKIIDYLENKEQKKGTKKGR"
     gene            7374..8432
                     /locus_tag="J8S10_001981"
     CDS             7374..8432
                     /locus_tag="J8S10_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliS"
                     /protein_id="HAZ9630563.1"
                     /translation="MEKNVNSTSTKDQYSIIGGLLGDKDKRTRHGLRIMLATFLGVLF
                     LLTGLGSYIYQLGNYNYYLVNNTTPIGSSLEFARSGAEITISDVWTDQNRDVTVVKLG
                     YSQNARKLLSTQGKNYNLYMATKEKDRPKKLEMSYGMLSTDGDAFLFLKGKLDERAYQ
                     VFIANQVSLISGDDTADDDTKVNVNEADSVTKALSQYSMNDVNNEGVISFGKKAKPVN
                     TPDNINFRINPYSDSTNVYQGSFLTKDGDIDYSKVVAVTSKNNVVSKLEDQLNASNTN
                     IKKIEATKAEYLERLQQNPDDKDSQESIRQLDSRMETEIKAINDTQKLIDQYKNADFN
                     KDSFGDMKTTFKYLTLTD"
     gene            8474..10423
                     /locus_tag="J8S10_001982"
     CDS             8474..10423
                     /locus_tag="J8S10_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HAZ9630564.1"
                     /translation="MENSTEFFKNIQTEFNHALTPMKPPKHKLVGRDDELHELSLILN
                     RPETPQAILLGEAGTGKTALASEWAERQRQDGKKVQVYKLSIGQLRVGGDDVLQTRLE
                     TLIPRLKEYERILKSEDKENEFVLFIDEFHKVVSSFGSGNKIGGDSLKEPLANESLQL
                     ITATTRKEYENYIKRDDALGRRLQPLELNELKSDVVVDILRQWLNTSSVKDDPQASFK
                     LSQRIPDELLQEIVQANKLYREDLSEPAKSIAVMEDLIAKDRVDGNAYNRESLLQIFG
                     KYNIQLDSDFDMEKLQEELKSIKGQPLAVYTITMLFKRMKLGFDRFKGRKQPKATALF
                     TGSTGVGKTAMAKAVARGLYGDENKVLLVNMPDYKTKDDAMRFRRLIGTHVRHDPSAI
                     IVCDEYEKAGVETLDAFLSILDEGRISFTERGWDDREVHDTVSLSNTILFATTNAGAE
                     MFDSLNRYSSLSRVTNKENSNEYSTELKREYRKVASGIKQALIGEGLKPEVINRFGRI
                     VPFWALSEQTLLEIAYNEMLKSAELVRKHLNIDLRLPPRKERVYGQNFYADDLSMHLV
                     FDMASQEDSKSGGARNILHLVESEFEEAITEAIITYPNAKIFDVKLSEAGAFEGKGDS
                     NAEIIAKPSVAESKENKIVFSIGGA"
     gene            10426..14067
                     /locus_tag="J8S10_001983"
     CDS             10426..14067
                     /locus_tag="J8S10_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630565.1"
                     /translation="MKFKKYLLQNLRIKRWVVRGLVIGGVLAVTLGAPFGMNDPTPDN
                     QDSKQETVINKNVAYAESKPAEQGMWTLYARILMGDKEVNDSAAKTGQMNLLGQGGIS
                     ADFPYSDISKQGNSIAGGNAGTQLASTLATYSYYGYIETVSGNAIASQASSILGSIGR
                     TIGSFIGSISLILSNIAESINELLGKFFMSMNIFSLMGWGEGGSDVSNPVSKALTSLL
                     NNLGLNNELFKAIASLSMLFFTAILGYQGMKLLSKDGVNSKGLSPVLEKWIVRIFVLF
                     IFLPVAGSLLGVYINGIQSAKKDGDIPTNVVSDYIINTRLWASTQNLAPSSDTGGDVP
                     DGKPTSEIKFVDTDYEPSKKSAMIRAINTSSYARQNNDLDSNSVGMALLKEWSSNDTF
                     NINTYAGDVNVAENDAYMGRAPAVWTGYNLGDGKEGSAIKKPTNLNGYIWSANQNVTD
                     DNRKPDGKGTAHNFDATQPWGVANNATFSTQSVALLLQSALDTSGAKFYAYNIAPSGI
                     QGSAKNMSTVKTEWRTASLVGHGAMGKFGSWLAMNAESIVLAVLYLACAWAMFNVNIV
                     KAFKREFIRIWEVVLTGSLASGAGVMAISLGVVTTSLIGLQLPIFLITFIRAFGDTAV
                     GFIPNTLVGDGVANIVRSAMILGVGYLLVFKKGEKVNNLINMLIGLPLEVAFGFDERA
                     KLLFGNRNDAVRVVDGVSKAIKKSQGAKNPYYDGGNSSVKDMVAGGLGAVGAQKMAER
                     LNNMGDSNADAKSIADKVIPETPEGMSFNGGGVGSTINNTSFKDLVRQDQLRNNSQQY
                     IDHLGRMVDENGNFVDENGEILKDSKYGKDAKGNFIDEKGRLVDEDGNLIDTNGKPLE
                     DSEDGNIGMDSEGRLIDEKGRLVDEDGNLVDENGRRLLNGDFGHDSNGRLVDEKGRLV
                     DEDGNLVDEFGNKLGKHSDGYNVNGDLVDEDGNIIETRDALVADRNRELEQQRHTPIA
                     VAIPENEEDEITLDQTHQELRNEMSGEDVSDRVHRELGDGASGESQSRELNSNFDNSA
                     IRNDTVLKDRESLTKETDKEQSDVKKKFIPTPNVNQTDKYETNIGSGMSKDNQSIREP
                     ELTNKNNRTNNSKSTSDNSGKSNQSTKKTSTAKSAVEYLSKTGKNVYTSADKALAKAP
                     KGSLAGITYEAKNEAIKIGKGTAKVAKATATGASKTGKVVKKSTMSVKDYIVKYGNQK
                     STENKSEDE"
     gene            14467..14805
                     /locus_tag="J8S10_001984"
     CDS             14467..14805
                     /locus_tag="J8S10_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630566.1"
                     /translation="MFDSIKNLVSGMTPDMKTLVQVVLYFLAFVFSLKPGFTAMKFFG
                     DAKWGDGLKYVGAIIAIFIIPVITTVMLYTMGTKTGNDLNQKANIISALIPVVGIYLV
                     SKFPKNELLG"
     gene            14915..15136
                     /locus_tag="J8S10_001985"
     CDS             14915..15136
                     /locus_tag="J8S10_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630567.1"
                     /translation="MVFDREKMLAHANEVLMSSLKGTELAKIMNMNVNQFYDYRNGSK
                     KIEKARLETLIKFEKAYVYMLDKQKRTID"
     gene            15156..17312
                     /locus_tag="J8S10_001986"
     CDS             15156..17312
                     /locus_tag="J8S10_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630568.1"
                     /translation="MAKFKDITESINYVAETVPVVALSLKPQLLEVYKKEEKEAKAKK
                     AKAKVWKEFDALLTKDLPKKNYMVIEDVQKLNSEGVIDEDDAILDSEKYVVLLKSSLN
                     YVADLPEKFKEKLLAGVRFMDSSGQLLVIPDDPNVFESEVEEATDFYSAVEQLEVATN
                     GLERIAETFNSSEEVEFEAVAENVPDEKEALFVDDNKPTEAENQEVSIEETQIQTETY
                     QQPKIDEKPESQSDKENYVYEAEKITSESDVPKNLDADFLEKNFEQIIADKFQPVVLD
                     EINDPVDLNEEMLSIPELKPLLFLAKESMNARISIANNKINSELNKTKEQLILKGKQM
                     LADELLRIEEATSLNGQNQFTNTLSVAKESYEAEASKIDDLVMEKSNIIRKDYDMAKQ
                     AYLDAELKKLEQRYDAEHLPEVKQQEDEYRKATEESLDQQYQEAIESIKNDALKQSQE
                     AKEVVVERIINSLKPEIEKSLTDVQEKTLEIVEKTKSENEAEFHDTKEKTTDVVVKYF
                     ANKEEVEKQVANNTKELETKLVEQQKTIEEYKDRMKEVKDLAEGYKLNSEKLAEQSEA
                     LREDLSRSRSDLAQMAEKTKSLAVATENQSSSKRDFTSKKMATIISVAAMACGTILGS
                     SYFISHNNQQAQAQTQTSISRVENSIGTNTNSASTNSSYEATPTTEFKVGKDVVISID
                     GKTTKAEVISIDGEKAVVKTPDGNQYKIQAHLSDNN"
     gene            17324..17557
                     /locus_tag="J8S10_001987"
     CDS             17324..17557
                     /locus_tag="J8S10_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAZ9630569.1"
                     /translation="MREEKIVYPVIQNNQENMTSSQHLQEAQLVYQVNELPQTNETMS
                     KSISLIGLLIVAIVITVGVYRKLNVKGSISDGR"
     gene            17547..18413
                     /locus_tag="J8S10_001988"
     CDS             17547..18413
                     /locus_tag="J8S10_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630570.1"
                     /translation="MADNSNYGFKHNLHQKPSETIVRVEWLEKHVNSTYSVTAKRLIV
                     SAIVVAVVVLGSIVYLVSDTIKLKFIFVPTLLMIIGFLILISQYMFIDPSSGSLISGS
                     IRLFKSVVNSARVSMGKKKPFRGTEILKVKQDGTIVYRDGSVALMFNLDGATSLTAFP
                     EEVMAQESKSIQYQNTRDRSLAEIKITSSQPQNTERQTRNMKIQKRNARSNKAVFDII
                     DQQERFVSEYIDGVKTTVIQYLILKSQSKMVLDEGVERLENYTSRGLYYSVTQLSAKQ
                     TKEILSDIYALK"
     gene            18428..20398
                     /locus_tag="J8S10_001989"
     CDS             18428..20398
                     /locus_tag="J8S10_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630571.1"
                     /translation="MEIMGRSQLLNFKKKRKTKKEQKTRNSKVVNNTFVSDLTSLVGY
                     QFTPSYIRTGKRWGTIVKLVNTYGMNRNYGFGWMVKAIPEVRVEGVKAYLIEADKPVS
                     QKDQQEIMHENVGGSTNSYENNLEGKNSDAEISKTVMRIMDLNTASLLDSMANKIIDW
                     KLEILLVSDSPNKISEQLIKLQRLYDEKMYGLKLMSYGGDQRDLFDRLLSEPIGNVYE
                     YTSMSSDFAGNDHAIRKGLDDANGWAIGTMSTSYASGVAFMALDDSFTSKVLVASHKN
                     ATIKGYDEKISASSLWGQLIANNAMANHKRTFHIVLNKFDYFGDPTGRTFVAKPSLNS
                     VIEKVNLAEEGLNSLELFGNQKDIGDLYRRNLDKLTQIFYLLAGRTLDSATRVLLKKE
                     LGNFYISQKLWDINYEERSKLLVNSSDTMPVLGDFISYLTNAETKAKKSGTEKEVDRI
                     IVLKDTLRTALDSFSRMFNQRTTLKEIGKSDKLQFYYNLGDLRAETNVMEAQFLNTFD
                     FITSQAKKDDIVMIHGFDKLSIETVGLIKKRLTMLEEDGIRLAFLFDTIGSGEDNEYK
                     EDIETADIFNTDGKIYQSFESDFNYTIIGKMTSGELMKYEKKVAPARKGEDDQKLSVD
                     LRQYLTTGRSNKFQIRRPVDLTNNFVIGEFIL"
     gene            20565..20792
                     /locus_tag="J8S10_001990"
     CDS             20565..20792
                     /locus_tag="J8S10_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630572.1"
                     /translation="MKPNIKILDRIFLGRDTEVILIQHEEGFEVSIGIQKLQKPHYCN
                     QLYKNFTDEEKARVFFNEVKGMREQYEVVEA"
     gene            20789..21283
                     /locus_tag="J8S10_001991"
     CDS             20789..21283
                     /locus_tag="J8S10_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630573.1"
                     /translation="MNKLPEKNRVFRLKGDLSQFKIDENGQFFVWMRHEHCWCNPFVL
                     KKENEIRTKIANGEWDYLFRWEDESFIANDMDHAFVSFLDNTWGTWYDCYLEKLGFQN
                     IDIDAIECLKEVDQKYEEEPYYLLQQKLANNSVFQVEIWENEDGTYEGLAQEIPFSDR
                     KSSI"
     gene            21458..21793
                     /locus_tag="J8S10_001992"
     CDS             21458..21793
                     /locus_tag="J8S10_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630574.1"
                     /translation="MKQYLNEWKAIEGSLVTQRIKELPDCLEKDHLFQIREMLKKEQF
                     DPDQFLVVEYPTIGVYCCNHINDGKYFIIQEYGGQLTPFYTTWEMSEEGINNFPCESI
                     EDSISHTEC"
BASE COUNT         8053 a         3229 c         4189 g         6739 t
ORIGIN      
        1 gaaaaaatta actagcacca cgggttaaaa catcctcttt ttctattgat tccatacaca
       61 acaatgtgta taatagattt tgtaaaggga gggtagctat gcctaagaca gcaagagaaa
      121 ttgtaaaaat tctcaaatct aacggcttca aaaagactgg acaaactggc agtcatgcaa
      181 aattttataa ttccaagact aaaagaacgg tcgttgttcc gatccacaat ggtgatgtac
      241 cactaggaac agaagctaat atctggaagc aagcagggct ttaacagcct tgccttccta
      301 tttggtatta ggcatactat cctctcttac actagaaaag gagcgaggaa atgaagacaa
      361 aaaatatttt ttatccggca atcttcgaga aagaaggaga agcttataac atcgttttcc
      421 ctgacttacc ggaaatatct acctttggaa atagtcttga agaagcatat ttaaacgcta
      481 aggatgcttt aggattagcg ctatatagtg taccagatgc agaatttcct aaaccatcag
      541 cagtggaaga attaactttg aaagccaacc aagtggtagt aatcatccaa ctaaacatta
      601 aacttttccg aagaagctta aatacaaaaa caattagaaa aaatgttagt gttccggaat
      661 ggttagttct tttagggaag gagaaaaaca taaacttctc tcaactactt caaaaagcac
      721 tagaagaaga gttgcttgaa aagtaaaaag gagaccgaac ctatgaaagc tacacactta
      781 aactatttct ctcgaacgtt aatcaataat ctattaaaag atacaactgg cattagcgtt
      841 agtaccaaac actttgccaa tgatctaatt atttttgagg ataataactt gcgaattgag
      901 atgtttattg aacaggcaac ccctaactca atacctgaat tctgctatac gcacactgaa
      961 aaaatgaaac atgcaaaatc agttaaagat gttgaagcat taagtgaatc actaacgaac
     1021 gctttaaacc tcgttaagaa ggcaaaattg ttatttgaat ttcaaaccga ctaccacaat
     1081 gagttgcttg ctcaatctga aattttagat taattgaaac aggagaagag aaagatgaaa
     1141 caaacacaaa cagaaaccgt taacgatacg cttgctgatc aattagcagg ttattataaa
     1201 ttatttgaga tgggtaaagc acagcgcttg atccactatc tttggaaata caaaattttg
     1261 tttctttttt gggaatcaac actaacattc tcagttcttt tttataagtc agatttttat
     1321 aatcaacact tagttttagg gagttttttg cttatctaca ccattttgat gcttaattta
     1381 tatacctaca tcacacttga agaacactta gtaattagcg atgcagggat cgagagaaac
     1441 atcaaaaggg tatccttcaa gatcacgtta aacaagccta ccgataaaaa gctctcagaa
     1501 gcgttctgag agcttttgac attttcttgt ataattttat cctaacacat tacaaagcac
     1561 ctaattcgag cttatatcaa gcaaatttgc tatttattac tcaatacata tctaaaaatt
     1621 acttgatgga aaattagata catggtaagc atgaaaagaa aatcaatttg agcagatgca
     1681 gtacaataca tagcaattta aaagctctca gaaggcttct gagagctttt aatatattct
     1741 ttgataattt gtctttctta aatccatacg tcctaaaaca agctgttttt gcttaatatg
     1801 atcatctgag agacatcaaa tcaacttttc tctcaacaaa tcattcaaag ctttcgacag
     1861 attaatattc tcttcagccg ctaaaacatt taaatagtgt tccacagtca ctgattttcg
     1921 atcataattt tgcttgtttc gagctttagc aactttcgta ttagctttta cgacaaataa
     1981 attaacattc tcagatcgct tgattcttgc atttaactct tgaacaggcg taggcgatgg
     2041 aatttctttt tcttgcaact ctaaaagcac caagtatcct tccaatactt cttgcgccat
     2101 ctcaaaagca tcttctaaag tttcaccatg tgtatataag tctggaaaat ctgggaattt
     2161 aactgcatat tcatttcctt tccattcgaa tactgcacaa aaaaagtatt tcatcgcatt
     2221 gcacctctct aattaaaaaa taatttttgc ttttttgttt caaaaaaaag aatcgcctac
     2281 caaaaaaatt gataggcgat cacaagctaa ttaacctcta aaggagatta ataccttgct
     2341 cccaaggcac tatatatctt agcatacgtc tgaagcatct tcaaacgagt aagatatatt
     2401 ttgcattaac ctaatttttt ttctctataa gttttttcat caaactcact agaaatatta
     2461 aactggacag caaaattgta atttctgcct tttctaactt tagcaaaatc aatattcagc
     2521 attgattttt cattaatttc ctcaactgat tcccttaaaa cacgtctatc aaaattcgat
     2581 attgttttat actcattttc tgttttcgta atctcacgaa ttttaactat ttcaatcagg
     2641 ggattcttat atatttcagc tttctcaaaa tctcctttat ttttggcgat aagatatttt
     2701 ttataataca tcgccaaata tttgtataac acgatgctat attttttttg aaaagatgct
     2761 aagtcttcaa aaacaaagaa cggatacttc tttttgattg agacaattaa gggaattaca
     2821 tcttctgaaa aactgaaaga tacactatgc tcttctaaat cccaatgaat ccgatcaata
     2881 gcagatacag tagtatacgt cttatatttt ttgtctagat tcgaaatttc ataaactgct
     2941 tgtctttgca aagtgttaac tatggttttt agttccgttt caagattttg atcaacatcc
     3001 atgtaattaa taatcgcttt aacaggtaaa tctactacgc ctgttttctt tagctttgtg
     3061 ggtgagatat aactgaacag caattgataa agttcatacg actttaaatc cattttcatg
     3121 tcaattgttg ctaagaactc ctcattgtac tttgtcagtt catctttttt caaaagtttt
     3181 tccttccttc acgcattttt tcagttgtta atcataaagg ttcacataag gcaaataact
     3241 cgtaattgat ttttcgagat atttaacagt attttttatt gtgtaatcct ccttatgagt
     3301 agcaacgtaa gataggtgat tgacaactga ttcaaatcct ctatctttgg ataaacgatc
     3361 ataaagcgga taaactttat tctgaagtcg gctcataagt ttaagatcgc ataagtcggc
     3421 agaactgatc aaaaagtttt tgattagtaa tttagtgtat ttgctattca tagctttcaa
     3481 gtacgattga ttcattttct ctgttttatc ttctgcgcct tttaaataag cagggtctct
     3541 ttgttcttgc ttataaggta ccggaactga catggtacgt gtaagcaaga actttatgtt
     3601 tgtataagta tgacccttct tgataagctc atagtcaatt ttaaaatcag tgtatttatt
     3661 cagttgggca atcggttctt taattacacg tctttcaaag tctcgaaaag ctttatattt
     3721 tttctcaata ctaaatttct ttcgtaaatc tgcaatggag aaaacaggat tttttaatct
     3781 atcaagtgat tttgtactcc atgttaagtt atctctattt gcttcataca gattaaaatc
     3841 tttagtgaat aattgaaaaa aactgatcgc atacttgctt gtcaagttaa ctacttgatc
     3901 aaatgtatat tgcgtaaaat gattttctaa gttcgttaat aaaggcataa ttgaactact
     3961 aaatttaata gatactgcat cagaaaaatc attgaattca gtaatttcta gcggtgagat
     4021 gactttgtat tcagtcttac cgttaggttt agttctttga attttaatga cagattgctg
     4081 atgcaatttt tcaataactt gttttaatct tgaatgtttt gaagaagatg aactagaaga
     4141 catcaacgca aataaagcct ttttagatac tttgacggta ttattaaaag gcggattttt
     4201 agggtcaaga tgtcctatag cgtaaagata aattttttgt ggcatagcat ccatttcaac
     4261 aatgctatct acaagttgat tcgataaagt aacagttaaa tcaaactttt ttagattgct
     4321 ttcggtagtt tcaaatttcg ggtttacatt cttttctgtt attttcatac gattgcctct
     4381 tctttctaag cttggtacga gcttaaaaac ttggaactgg tacgattcca ttgaataagt
     4441 atagacctgt tttcgatacg ttacaataag aaatgtatcg taaatttata acataactca
     4501 atgtcagtaa aacacatttt attttttcca atcaaatttc attgaaaata cagcagaaat
     4561 cgctatttta gaacattttc aaaataaaaa tccttttcaa taaaatacga aattataaaa
     4621 attaccaaaa ttaaaaaaca aatatttttc tagtttttag aaataaattc acatactttt
     4681 tctttttttg gatatattcg gaataccaca tcgctttttg tccacgtttg catcgctttt
     4741 tgtccacatt cacatcgctt tttgtccatg ttcgcatcgc tttatgtcca ccctaaaatc
     4801 tatttaagat tgatataaag cctttttgga ggttgctaaa gttttaaaga ttaaaatata
     4861 tattataaat ataaataaaa ggggaagctg aagcttcctc cttttccttt ttttcaatta
     4921 ttcaaagtta cacaagcaaa ataaactcct agatagtgtt agtttttttt aagatttttt
     4981 atttttaaga ttttgaaata agagaggagt aatcctcctt tattaaatat ctgttaatat
     5041 atctgttaaa tatctgttaa tatatctgtt aggggaggct taatctcttg ggagagtaag
     5101 tattaaaggg gtataaaggt aacacttttg gacagtaaag gtaacaaaag tggacagtaa
     5161 gggtaacagt tttggacagc aaaggtaaca aaagtggaca tttgaggtat cacactagga
     5221 taagacgtta ccttcggttt tcttgatttg gaaggcgaaa aaatagaaaa ttagattagt
     5281 aacaaatctt tgttgactgt tacctttagt tgtgatttaa tttaggtaac aagcagaaaa
     5341 aattgtttcc tttaattagt accagattaa catgattaaa ggagcgcaaa aagaagattg
     5401 gagagtaatc aatgtctcaa gaagttaccg aaaagattat tgatagtgat gtagatttag
     5461 tatcagaaca aacaaatgca attgtgcgtt ataacaatgg tctgaataca acagctttgc
     5521 gaggatttaa gcctgttgaa atggatgtgt tttgggctat tttatcaaaa atgaaacgtc
     5581 aaggaacagc agaagtaact tttgatttca acctctttcg ttatttggtc aaatacgaca
     5641 gaagagaaaa ggacagtttt tattctgtgt taaaagattt gagtgacaaa ctaggtaatt
     5701 taacctaccg ttttgaagat tcagacgtct atgaacagct gtggcttttt caaaaattcc
     5761 ggatagataa acagaaggaa acagttacaa ttaaggcaaa tgaggaattt gaatttatct
     5821 taaactcaat tggcaaaaac tttactcgtt ttgaacttga taattttaca aaactaagaa
     5881 gtagctacac aaaagaattg tatcgtcatc tcatgcaata cagaaataaa gagtggcgaa
     5941 atggttattg ggtagtcaaa gttgaagatt ttagaagagc attaagtata ccttcaagtt
     6001 atagaatgac aaatattgat aaaagaatac tagagcaggc gaaagaagaa tttttagctc
     6061 ctgatgaaaa cggaatacag gtatttgaaa cttttgatta tgaaaaaatc tatgcaaaga
     6121 aaggaagaag agttgatcgg ctcagattca cttttagtga gccagaatca aacttgccaa
     6181 ccatttcaat gcataattgg ttagaagaag attgagaaga agcaggttgt aattttaata
     6241 caacctgctt ctttaaaaaa gtatgggtaa cacttttgga caataaatgc aagaagtttt
     6301 tttgtaagca agtttcagtc taaataatat ttgaaagaat ggctaatcta tacaaatttt
     6361 aacaactatg ggtaacactt ttggacaagt caagaaaaaa aacaattttt cttaatttgt
     6421 tgatcgacta aaggtaacac ttttggacaa cacagaataa aaagtccggt gatatcagtt
     6481 ttggtaggaa acatcttaat atctttgtga gattgaaggt aacatttttg gacaagtcaa
     6541 ctatttgtta aaagttaata tagagtaatt agataagttt tttcttttcg tctgataaat
     6601 ggataatatt agttatttta ttgctaatta gtctttcatg atgactgaaa tagctaaaat
     6661 aaatatctcg ttggataatt gctgatactt taagggatat ctaaatttgc tgattgattt
     6721 atttatgtta ttatgatatt ataataacat aaatgtgtta cgcccgaacc tcattttaaa
     6781 aaaatgaagg ggtgagacaa tgaatgctat taattggcat gaatttgtta actatatgga
     6841 gagcttacta gatgatctaa aaagttttag tattgctgat gcagtaaagc atgggttacc
     6901 agttagtaca acgatgaaat tacgaggatt gaaaattcca gatgaaatta ttaagctgag
     6961 aactaaaaca attattgaaa ccgcaaaagt cgttgacaat atgaaccatg aactaaaagg
     7021 caagaaaaca acttacgaga aagattttga acgtttttta aaatctgtta ttggaaaata
     7081 tctaggtaaa aaatctttca gtgaattgag agatgaagag attgtaccta ctccaatggt
     7141 tagcaaaatc cgaaaaaaca aagccgaggg gaattactat cttggtacaa tagcaaaaat
     7201 cattgattat ttggaaaata aagagcaaaa gaaaggaacg aagaaaggaa gataattttt
     7261 gtgttaaata ttaatgggga agaatatacc gaaatgattc aaaatcccga acctagaatt
     7321 accgaaaaaa cgtctgattg tttgctcttt tatgaaaggg ggcagacaaa ctaatggaaa
     7381 aaaacgtcaa ttcaacatct accaaagatc aatacagtat tattggaggg ttgcttggtg
     7441 ataaggataa gagaacacgt cacggattac gcattatgct tgcaactttt ctaggagtgc
     7501 tttttttatt aacaggcttg ggtagctaca tttatcaatt aggaaactat aattattatc
     7561 tcgtgaacaa tacaacacct ataggctctt cattggagtt tgctcgatca ggagcagaga
     7621 tcactatttc agatgtgtgg acagatcaaa acagagatgt aacagtagta aaactcggtt
     7681 actcgcaaaa cgctagaaag ttgttatcta cgcaaggaaa aaactacaac ttatatatgg
     7741 caacgaaaga aaaagatcgt cctaaaaagc ttgaaatgag ctatgggatg ttaagtactg
     7801 atggggatgc tttcttattc ctaaaaggta aattagatga aagagcttat caagttttta
     7861 ttgcaaacca agtatcacta atttctggtg atgatacagc tgacgatgat accaaagtca
     7921 atgtgaatga agcagattca gttacaaaag cactttctca atattctatg aatgatgtta
     7981 ataatgaagg agtaatttct tttgggaaaa aagcaaaacc tgttaatact cctgataata
     8041 tcaatttcag aataaatcca tattcagatt caactaatgt ctatcaagga agctttctta
     8101 ccaaagatgg cgatattgat tattcaaaag ttgtagcagt tacaagtaag aataatgttg
     8161 taagtaagtt agaagatcag ttaaatgctt caaatactaa catcaagaaa attgaagcta
     8221 caaaagctga gtatctggaa cgtttacaac aaaatcctga cgataaagat tcgcaagaaa
     8281 gtattcgtca actagacagt cgaatggaga ccgaaattaa agcaatcaat gatacacaaa
     8341 aattgattga tcaatacaaa aatgctgact ttaacaaaga ttcttttgga gacatgaaga
     8401 cgacatttaa gtacctaact ctgactgact agaagtaaat tattcttatt ttagaggaag
     8461 tgaacacaaa cagatggaaa atagtaccga gttttttaag aatattcaaa ctgaatttaa
     8521 tcatgctctc acaccaatga aaccaccgaa acataagtta gtgggacgtg atgacgaact
     8581 ccatgagttg tcactgatct tgaatagacc ggaaacaccg caagctatct tgttaggtga
     8641 agccggaaca ggtaaaacag cacttgcaag tgaatgggct gaaagacagc gacaagatgg
     8701 aaagaaagta caagtataca aattatcaat cggacaattg cgtgttgggg gagatgatgt
     8761 cctccaaaca cgtttagaaa cattaattcc aagattgaaa gaatatgagc gaattttaaa
     8821 atctgaggac aaagaaaatg aatttgtcct cttcattgac gagtttcata aagttgttag
     8881 ctcttttggt agtggcaata aaattggggg tgattcgcta aaagaaccgt tagcaaatga
     8941 atcacttcaa ttgattaccg ctactacaag aaaagaatat gaaaactata tcaaaagaga
     9001 tgatgcctta gggagacggt tacaaccgtt agaattgaat gaactaaaaa gcgatgttgt
     9061 cgtcgatatt ttgagacaat ggctaaatac atcctctgtt aaagatgatc ctcaggcttc
     9121 ttttaaatta tcgcaaagga ttcctgatga attacttcaa gaaatcgtac aagcaaacaa
     9181 gctttatcgt gaggatttgt ccgaaccggc taaatcaatt gccgtaatgg aggatttgat
     9241 tgcaaaagat cgagtagacg gaaatgctta taatcgagaa agtctattgc aaatatttgg
     9301 taagtataat attcagctag attctgattt tgatatggaa aaacttcaag aggaattaaa
     9361 gtccataaaa gggcaaccgt tagcagttta tactataaca atgttgttta aacgtatgaa
     9421 gcttggattt gatcgtttta aaggtcgaaa gcaaccaaaa gcaactgctc tgtttacagg
     9481 atcaacaggg gtcggtaaaa ctgcaatggc taaagccgtg gcaagaggac tttatggcga
     9541 tgaaaataaa gttctcttag ttaatatgcc ggactacaaa acaaaagatg atgcaatgcg
     9601 ttttagacga ctcataggta ctcatgtaag gcatgatcct tctgcgatta ttgtgtgtga
     9661 tgaatatgag aaagctggtg tagaaacact cgatgccttt ttatcaattt tagatgaagg
     9721 taggataagt tttactgaaa gaggatggga tgatcgagaa gttcacgaca ctgtttcatt
     9781 gtcaaataca attttatttg cgacaacaaa tgcaggtgcg gagatgttcg attcgttaaa
     9841 cagatatagc tcactatctc gtgttacaaa caaggaaaat tctaatgaat atagcactga
     9901 actaaaaaga gaataccgaa aagtcgcatc agggatcaaa caagccttga ttggtgaagg
     9961 tctaaagcct gaagttatta accgatttgg acgaatagtt ccattttggg ctttatccga
    10021 acaaactctt ctggaaattg cttataatga aatgttgaag agtgctgaat tagtacgaaa
    10081 acatttaaat atagatttac gtcttccacc taggaaagaa agagtatatg gtcaaaattt
    10141 ttatgcagac gatctctcca tgcacttagt ttttgacatg gcttcacaag aggattctaa
    10201 atcagggggt gcaaggaata tcttgcattt agttgaatct gagtttgaag aagcgattac
    10261 tgaagcaata attacttatc caaacgcaaa aatattcgat gttaagttga gtgaagccgg
    10321 agcgtttgaa ggaaaaggtg attctaatgc tgaaattatt gcaaagcctt ccgttgctga
    10381 aagtaaagaa aacaagattg tattttcgat tggaggggcg tagctatgaa attcaagaaa
    10441 tatttactac aaaaccttag aataaaacga tgggtcgtaa gaggtctagt tattggagga
    10501 gtattagcag ttactttagg cgctcctttt ggaatgaatg atccaactcc tgacaatcaa
    10561 gatagcaaac aagaaacagt tataaataag aacgttgcat atgcggaaag taaaccggca
    10621 gaacaaggaa tgtggacact atatgctcgt atcctaatgg gagataaaga agttaatgat
    10681 agtgccgcta aaactggaca aatgaatttg ttaggacaag gtggtatcag tgccgatttc
    10741 ccttattctg acatttctaa acaaggtaat tcgattgcag ggggtaatgc aggtactcaa
    10801 ctagcatcta ctttagcaac ttatagttac tacggatata ttgaaacagt ctcaggaaat
    10861 gctattgcca gtcaagcatc atccattcta ggaagtattg gtaggacgat tggtagtttt
    10921 atcggatcaa ttagtttaat cctttctaat attgctgaat ccataaatga actccttgga
    10981 aaatttttca tgagtatgaa tatattttct cttatggggt ggggagaagg tggatcggat
    11041 gtatctaatc cggtatctaa agcattaact agcttgctta acaatttggg attaaataat
    11101 gaattattta aagcgatagc aagcttatct atgctctttt tcacagcaat actaggttat
    11161 caaggaatga aattattgtc gaaagatggt gttaactcga agggattatc accagtactt
    11221 gaaaaatgga ttgttcgtat ttttgtattg tttatattct taccagtggc aggatcgcta
    11281 ttgggagttt atatcaacgg catccagtca gcaaaaaaag atggagatat accaacaaat
    11341 gttgtttctg actacatcat taacacaaga ctttgggctt ctactcaaaa tcttgctcca
    11401 tcatctgata ctggtggtga tgtacctgac ggaaagccta catccgaaat caagttcgtt
    11461 gatacagatt atgaaccatc taaaaaatct gcaatgataa gagcgatcaa tactagcagt
    11521 tatgccagac aaaataatga tctagattct aattcagtcg gtatggctct attaaaagaa
    11581 tggtcatcga atgatacttt caatattaat acttatgccg gtgatgttaa tgtcgccgaa
    11641 aatgatgctt atatgggaag agcgcctgct gtttggacag gctataattt aggggatgga
    11701 aaagaaggaa gtgcaattaa gaaaccaacc aatttaaatg gatatatttg gtcagcaaat
    11761 caaaatgtga cagacgacaa tcgcaagcct gatggaaaag gaacagcgca taactttgat
    11821 gctactcaac cttggggcgt tgctaacaat gcaactttta gcacacagtc ggtagcttta
    11881 ttgctccaat cggcacttga tacatcggga gctaagtttt atgcgtataa tatcgctcct
    11941 tcaggaattc aaggcagtgc taagaatatg tcaacagtaa aaacagaatg gcgtacagca
    12001 tccttagttg gtcatggagc tatgggtaag tttggctcgt ggctagcgat gaacgctgaa
    12061 tcaatcgttt tagcagttct ttacttagca tgtgcttggg cgatgttcaa tgtgaatatc
    12121 gtgaaagcat ttaaacgtga atttattcgg atttgggaag tagttctaac aggatcactt
    12181 gcatcaggag caggtgtgat ggcaatttca ttaggtgttg ttacaacatc tctgatcgga
    12241 ctacaattac ctatctttct gattactttt attcgtgcat ttggtgatac tgctgtggga
    12301 ttcattccta atacattagt tggcgatggc gtagcaaata ttgttcgatc tgctatgatt
    12361 ttaggtgtag gatatctttt agtctttaaa aaaggcgaaa aagtaaataa tttgattaat
    12421 atgcttattg gcttaccact tgaagtagcg tttgggtttg atgaacgtgc taagttatta
    12481 tttggtaata gaaatgatgc tgtgcgagtt gtggacggcg tttctaaagc aatcaagaaa
    12541 agccaaggag ctaaaaatcc ctattatgat ggtggcaaca gctcagtaaa agatatggtt
    12601 gcaggaggtc ttggagcagt tggagcgcaa aaaatggctg aacgtttgaa caatatggga
    12661 gatagcaatg ctgatgctaa gtccattgct gataaagtaa ttcctgaaac accagaagga
    12721 atgtcattca acggtggcgg agttggttcc acaatcaata atacctcttt caaagattta
    12781 gttcgtcaag atcaactacg taataactcc caacaatata ttgatcattt aggacgtatg
    12841 gttgatgaaa acggaaactt tgtcgatgaa aatggtgaaa tattaaaaga tagtaaatac
    12901 ggtaaagatg ctaaaggcaa ctttattgac gaaaaagggc gtttggtcga tgaagatgga
    12961 aaccttatag atactaatgg taaaccattg gaagatagtg aagatggtaa tattggtatg
    13021 gatagcgaag gacgtttaat tgatgaaaaa ggtcgcttag tcgatgaaga tggaaatctt
    13081 gttgacgaaa atggacgcag gttgctaaat ggtgattttg gtcatgatag taacggacgt
    13141 ttagttgacg aaaaaggtcg tttagttgat gaagatggaa atcttgttga tgagtttggt
    13201 aataaacttg gtaaacacag cgatggatat aatgtgaatg gagatttagt cgatgaggat
    13261 gggaatatca ttgagacgag agatgcgctt gtggcagatc gaaatagaga actcgaacaa
    13321 caacggcata cgccaattgc tgttgcaatt cctgagaatg aagaagacga gattacttta
    13381 gatcaaactc atcaagaact gaggaatgaa atgagtggtg aggacgtgtc agacagagtg
    13441 catcgggaat taggagatgg agcatctggt gaaagtcagt caagagagct taacagcaac
    13501 tttgataata gtgctattcg gaatgacaca gtacttaaag acagagaatc gctaacaaaa
    13561 gaaacggata aagaacaatc agatgtgaag aaaaagttca ttcctactcc taatgttaat
    13621 caaacagata aatatgaaac aaatattgga tcaggaatgt cgaaagacaa tcaatcaatt
    13681 agagaacctg aactgacaaa taaaaataat agaacaaata attctaaatc tacttcagat
    13741 aattcaggga aatctaatca atcaaccaag aaaacatcaa cagctaaatc agccgttgaa
    13801 tatctatcaa aaactggtaa aaatgtttac acctcagcag ataaagcttt agcaaaagct
    13861 ccaaaaggta gtctagcagg gataacctat gaagctaaaa acgaagctat taaaataggt
    13921 aaaggaacgg ctaaggttgc caaggctact gctacaggag catccaaaac tggtaaagta
    13981 gtgaagaaat ctaccatgtc agtcaaggac tatattgtaa aatacggtaa tcaaaaatca
    14041 actgaaaata agtctgaaga cgagtaaaaa gaaggagcat tgatttgctc cttcttttta
    14101 ctttgatttc taactgaaga tgtcaaggaa aatttctatt tatgcaaaaa aattatttta
    14161 aattgtctat aaatgaatta aatatttact gttcaaagtt gtataattaa aaagggctta
    14221 tgctggtaaa gaacagaatt attatctaaa caaaaacttg ataaaccagc atttttagcc
    14281 aataaaaaaa gtgaaataat ttaatggaaa atctctttta atcatcgaaa atttatgtta
    14341 ttatgataac ataaagatgt aaatatcgag acgtcttttt cttagttaga tcattgacaa
    14401 gtgaacaaat aagatttgtc gatgatataa ttaacttatt aaaaatatta aaaaggaggt
    14461 ttttatatgt tcgattctat taaaaatttg gttagcggaa tgacgcctga tatgaaaact
    14521 ttagtacaag ttgttttgta tttcttggca ttcgtttttt cgttgaaacc aggattcact
    14581 gcaatgaaat tttttggtga tgcaaaatgg ggagatggat taaaatatgt tggggcgatt
    14641 attgcaatct ttattattcc tgtaattaca accgttatgc tttacacaat gggtactaaa
    14701 acaggtaatg atttgaacca aaaagctaat atcatatcag cacttattcc agttgttggt
    14761 atctatctag tttcaaaatt tccaaaaaat gaactgttag gttaaaagtg aattgaacaa
    14821 atttggataa tatgccgatt tgttcaattt actttttacc aaaaaactac gctccaagcg
    14881 tagtttagaa gtgagggaag aaagtaaatg taagatggtt tttgatagag aaaaaatgtt
    14941 agctcacgcc aacgaagtat taatgagcag tctgaaaggt accgaactgg caaagataat
    15001 gaatatgaat gttaaccagt tctatgatta tcgaaatggg agtaaaaaga ttgaaaaagc
    15061 cagacttgaa acgcttatta aattcgaaaa agcatatgta tatatgctag ataaacagaa
    15121 aagaactatt gactgaaaaa aggagtttta caataatggc aaaattcaaa gatattaccg
    15181 aatctattaa ttatgtggca gaaacagttc ctgtagttgc actctctttg aagccacaat
    15241 tactcgaagt gtacaaaaaa gaagaaaaag aagcgaaggc aaaaaaagct aaagcaaagg
    15301 tatggaaaga attcgatgcg ttgctgacca aagatttacc aaagaaaaat tatatggtaa
    15361 ttgaagatgt acaaaagctc aacagtgagg gagttataga tgaggatgat gctattctcg
    15421 attctgagaa gtatgtcgtt ctattgaagt caagtttgaa ttatgtagct gatctaccag
    15481 aaaaatttaa agagaagcta ttagcaggtg tccgttttat ggatagtagt ggtcaattat
    15541 tagttattcc ggatgatcct aatgtgtttg aatcagaagt tgaagaagct acagacttct
    15601 atagcgcagt agagcaatta gaagtagcta ctaatggatt agaacgaatt gctgagacct
    15661 tcaactcttc tgaagaagtt gaatttgaag ccgtagcaga aaatgtacca gatgaaaaag
    15721 aagctctttt tgtggatgat aacaaaccaa ccgaagcaga aaaccaagaa gtaagcatag
    15781 aagaaacaca aatacaaaca gaaacctacc aacaaccaaa aattgatgaa aaacccgaat
    15841 cccaaagtga caaagaaaat tatgtttatg aagctgaaaa aatcacatct gaaagtgatg
    15901 taccgaaaaa cttagatgct gattttttag aaaaaaattt tgaacagatc attgctgaca
    15961 aatttcaacc tgtagtttta gatgagatta atgaccctgt cgatttaaac gaggagatgc
    16021 tatccatacc tgagttgaaa ccattgctgt ttttagctaa agagagtatg aacgctcgca
    16081 tctctattgc taataataaa atcaacagtg aattaaataa gacgaaggag caattgatcc
    16141 tcaaaggaaa gcaaatgtta gctgatgagc ttttgcggat agaggaagca acctcattaa
    16201 atggtcaaaa tcagtttaca aatacactat cggttgctaa agagagctac gaagcagaag
    16261 catctaaaat tgatgattta gtgatggaaa aatccaatat cattcgtaaa gattatgata
    16321 tggcgaaaca ggcttatttg gatgctgaac taaagaaact agagcaacgg tatgatgctg
    16381 agcatttacc agaagttaaa caacaagaag atgaatatag aaaagcaact gaagaaagtc
    16441 ttgatcaaca gtaccaagaa gcaattgaat ctattaaaaa cgatgcattg aaacaaagcc
    16501 aagaagcaaa agaagttgtg gtggaacgaa ttatcaattc attgaaacca gaaattgaaa
    16561 aatcattaac agacgtgcaa gaaaaaactt tagagattgt cgaaaaaaca aagtcagaaa
    16621 atgaagctga gttccatgat acaaaagaga aaacaacaga tgtggttgtc aaatattttg
    16681 cgaacaaaga agaagttgaa aagcaggtag ctaacaacac gaaagaatta gaaacaaaac
    16741 ttgtagagca acaaaaaact atcgaagaat ataaagatcg aatgaaagag gtcaaagatt
    16801 tagcagaggg ttataaatta aatagcgaaa agttggcaga acaaagtgaa gctttaagag
    16861 aagacttatc tcgttcccga agtgatctag ctcaaatggc agaaaaaacg aaatcattag
    16921 cagttgctac agaaaatcaa tcaagttcaa aacgtgattt tacaagtaaa aagatggcta
    16981 ctatcatttc tgtcgctgca atggcttgcg gaacgatctt gggatcgtcc tactttatta
    17041 gtcataataa tcaacaagca caggctcaaa ctcaaacatc tatttcgaga gtggaaaatt
    17101 cgattgggac aaatacgaac tctgcttcaa caaatagtag ctatgaagca acaccaacta
    17161 cagagttcaa agttgggaaa gatgttgtca tcagtattga tgggaaaaca actaaggctg
    17221 aagtgatttc tattgatgga gaaaaagcag ttgtgaaaac tccagacgga aatcagtaca
    17281 aaattcaagc tcacttatct gataataact aaggagggct attatgcgag aagaaaaaat
    17341 agtttatcca gtaattcaaa acaatcaaga aaacatgacc tcttctcagc acttacagga
    17401 agcacagctc gtgtatcagg taaatgaact accacaaacg aacgagacaa tgagcaagtc
    17461 aatatcttta attggcttgc ttattgttgc aatagtgata actgtaggtg tttaccgtaa
    17521 gttgaacgtg aaaggaagta tttctgatgg cagataactc aaactatgga tttaaacata
    17581 acttacatca aaaaccttct gaaacaattg tcagagttga atggcttgaa aagcatgtca
    17641 atagcaccta ttctgttaca gcaaaaagat taattgtatc agctatagtt gttgcagtcg
    17701 ttgttcttgg atcaattgtt tacttagttt ctgatacgat taaactgaaa tttatttttg
    17761 ttccaacgtt attaatgata attggatttc ttattctaat tagccagtat atgtttattg
    17821 atccatctag tggttcattg atttctggtt ctattagact gttcaaatca gtagttaatt
    17881 cagcaagagt atctatgggg aaaaagaaac catttcgagg cacagagatt ttaaaagtga
    17941 aacaagatgg aacaatcgta tatcgagatg ggagtgtagc attaatgttc aatctagatg
    18001 gggctacatc actaaccgct tttccagaag aagttatggc tcaggaatcg aaatcaatac
    18061 aatatcaaaa taccagagat cgttccttag ctgaaatcaa aatcacttca tctcaacctc
    18121 agaatacgga aagacaaact cgaaatatga aaatacaaaa acgaaatgca aggagtaaca
    18181 aagcagtctt tgacataata gatcagcaag aacgatttgt atcagaatat attgatggtg
    18241 tgaaaacaac agtaatccaa tatcttatct tgaaatctca atctaagatg gtattggatg
    18301 aaggtgtgga acgtttagaa aactatacga gtagaggact ttattatagt gtcactcagt
    18361 tgtcagctaa acaaacaaaa gaaatattat ctgatattta tgcactgaaa tagaggtgag
    18421 agattaaatg gaaattatgg gtagatcaca actattaaat ttcaaaaaaa agagaaaaac
    18481 taaaaaagaa caaaaaacta gaaattcaaa ggtagtgaat aatacctttg ttagtgattt
    18541 aacatcttta gttggttatc aatttacacc atcttacatt aggacaggta agcggtgggg
    18601 aacaattgtg aaattagtga atacttatgg aatgaataga aattatggat ttggttggat
    18661 ggttaaagct attcctgaag tgagagtaga aggggtaaaa gcctatctaa ttgaagcaga
    18721 taagccagtg tcacaaaaag atcaacaaga aataatgcac gagaatgttg ggggatcaac
    18781 gaatagttat gaaaataatt tagaaggaaa aaattcagat gctgaaatta gcaaaactgt
    18841 tatgcggatt atggatttga atacagcatc tttactagac agcatggcaa ataaaattat
    18901 tgattggaag ctagaaatcc tattagtatc cgattctcct aataaaatca gcgaacagct
    18961 aattaaactc caacggttgt atgatgaaaa aatgtatgga ttaaagctta tgtcatatgg
    19021 aggagatcaa cgtgatctgt ttgatagact tttaagtgaa ccaatcggga atgtctatga
    19081 gtatacgtct atgagttcgg attttgcagg aaatgatcat gcaattcgca aaggtttaga
    19141 tgatgcgaat ggatgggcta tcggcactat gtctactagc tacgcaagtg gtgtagcttt
    19201 tatggcactg gatgattctt ttacaagtaa agttttagtg gcatcacaca aaaacgctac
    19261 aattaaaggc tatgatgaaa aaatctcagc atcatcactt tgggggcaat tgattgctaa
    19321 taatgcaatg gcaaatcata aacgaacttt tcatattgtc ttaaataaat ttgattactt
    19381 tggtgatcca actggtagaa catttgttgc caaaccttcg ttaaacagtg taatagaaaa
    19441 ggttaatttg gctgaagaag gtcttaactc tttggagctt tttggtaatc aaaaggacat
    19501 tggtgattta tatagacgga atctcgataa actaactcag attttttatt tgttagcagg
    19561 cagaacatta gattctgcaa ctagagtttt attgaaaaaa gaattaggta acttttatat
    19621 aagtcagaaa ctttgggata ttaattatga agaacgttca aaacttttgg tgaacagtag
    19681 tgatacaatg ccagttcttg gggattttat tagctatttg actaatgctg aaacaaaagc
    19741 caaaaaatct ggtactgaaa aagaagtcga tcgtattatt gtattaaaag acacattgag
    19801 aacagcatta gacagcttct ctaggatgtt taatcaaaga acgacactga aagaaatcgg
    19861 taaaagtgac aaattacagt tttactataa cttaggtgat ctaagagcag aaaccaatgt
    19921 tatggaagct caatttttaa atacctttga tttcatcaca tcacaagcaa aaaaagatga
    19981 tattgttatg attcacggct tcgataagtt atctattgaa accgttgggc taattaaaaa
    20041 aagattaaca atgcttgaag aagatggaat tcgtcttgcc tttctatttg atacaatcgg
    20101 ttcaggagaa gacaatgaat acaaagaaga tattgaaaca gctgatatat tcaatacaga
    20161 tggaaaaatt taccaaagtt ttgaaagtga ttttaattac actatcattg gaaagatgac
    20221 cagtggagag ttaatgaagt atgaaaaaaa agttgctcct gctagaaaag gagaagatga
    20281 tcaaaaactt tctgttgatt tgagacagta tttgacaaca ggaagaagta ataaatttca
    20341 gatcaggaga ccagtggatc tgactaataa ttttgttatt ggagagttta ttctttaagt
    20401 tttatctttg attttgagtg tataaggaaa ggataagaaa aaacatgtat atttgagact
    20461 aaaaacagtc ttagagaaca tggtacgttt tgtgaaaaga gaactataga aatttcataa
    20521 agtgaaacct tattgagtga aataattata gtggaggtta aataatgaaa ccaaacataa
    20581 aaattttaga tcgaatattt ctaggtagag acacagaagt aatcctaatt caacatgaag
    20641 aaggatttga agttagtata ggtattcaga aacttcaaaa acctcattat tgtaatcagt
    20701 tgtataaaaa ctttactgat gaagaaaaag cgagagtttt ttttaatgaa gtcaaaggta
    20761 tgagagaaca gtatgaggtg gttgaagcat gaataagtta ccagaaaaga accgtgtatt
    20821 tagattgaaa ggtgatctca gtcaatttaa aatagatgag aatggacaat tttttgtttg
    20881 gatgcgacat gagcattgtt ggtgtaatcc ttttgtgtta aaaaaagaaa atgaaatcag
    20941 aactaaaatt gcaaatggtg agtgggatta cctcttcaga tgggaagatg aatcttttat
    21001 agcaaatgat atggatcatg catttgtctc atttctggat aatacatggg gtacttggta
    21061 cgattgttac ctagaaaaat tgggctttca aaatattgat attgatgcta ttgaatgtct
    21121 taaagaagtc gatcaaaagt atgaagaaga accctattat ctcttgcaac aaaaattagc
    21181 caataattca gtgtttcagg tagaaatttg ggaaaatgaa gatggaactt atgaggggct
    21241 agcgcaagaa atacccttct cagataggaa gagttcgatt tgaaaagagt atatcagcaa
    21301 tttttatgaa gtgaaagcaa gcttacaata tagtaatgga aaattgtggt tagctggaag
    21361 gtatattcca gctaaccaaa tcttacgttt tctgggagag tggcgtttta aaacaatttc
    21421 ctaggaaaaa tagttaacat aaaaggaatg aattgttatg aaacaatatt taaatgaatg
    21481 gaaagcgata gaggggtcat tagtaacgca aagaataaag gaattacctg attgcttaga
    21541 gaaggatcat ttgtttcaaa tacgagaaat gttgaaaaaa gaacagtttg atccagacca
    21601 atttttagta gtcgagtatc caactattgg agtgtactgt tgtaaccata tcaatgatgg
    21661 aaaatatttt attattcagg agtatggagg acagttaact cctttctata ctacatggga
    21721 aatgagtgaa gaaggaatca ataattttcc atgtgaaagc atcgaagatt caatttcaca
    21781 caccgaatgt taattgatta taactataaa aaaggattga acattatgtt caatcctttt
    21841 ttcaatgaaa tgttttccgc catttcattg tttggtgcga tttctatttt attatatcaa
    21901 aataaagaga gattctaaag aaagaagagg gaaatatata aatcaagcga cagtatattt
    21961 attattaaat gctattgtga gaatataact aattagttta atttgaaagt aaatatacgc
    22021 tataaaagtg catcttgtgt tataaaaaat tattttattt tgtgaacata atttaacaat
    22081 tctttctcgg aattgatttc ttttcttaaa tagtcttcag acttattaat aatattatct
    22141 attatgtcta gatacatatc acttttcgat tcagctaatt catacagttt ttttaattct
    22201 ttatccttta
//
LOCUS       DADQDV010000052        21972 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.052, whole genome shotgun sequence.
ACCESSION   DADQDV010000052 DADQDV010000000
VERSION     DADQDV010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 21972)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21972)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21972
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.052"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(369..995)
                     /locus_tag="J8S10_001993"
     CDS             complement(369..995)
                     /locus_tag="J8S10_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630575.1"
                     /translation="MDKAEFTNFYWKYYLHLENEFINTTDFVMLDENNFKTFSIEYQK
                     LLLAIGSECEIIFKELCGFDSSSNKSITDFKAVIKSSELMCLDNGVRVMNSLTLTSLK
                     PFGDGWPEDTPDWWKIYNRVKHGRSSNYKEANLENVLYALASLYLLEEYLHKKVILEG
                     EVDFISPESNLFTLSWERKHSSMQKVTFEKVDSNYVAPLIDFKEQEEI"
     gene            complement(1290..1625)
                     /locus_tag="J8S10_001994"
     CDS             complement(1290..1625)
                     /locus_tag="J8S10_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HAZ9630576.1"
                     /translation="MPIIKNVNELTERVKFKKTKRVKDEDGQMVDSEETVFECWANVR
                     SQMLKDVLASVGTILEGTLTFIIRYDQDYELTNDMKVAWKNKSYKIISINEGTAFKDY
                     TTIIAKQIS"
     gene            complement(1612..1896)
                     /locus_tag="J8S10_001995"
     CDS             complement(1612..1896)
                     /locus_tag="J8S10_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HAZ9630577.1"
                     /translation="MVILDSIKKSMRIDHTIDDDFIQQLIDTAGEYIKSAIDSSATDK
                     DMDNYQQFDLAVSLLTQHWYLNRQEASSERIPVTVQALVQQMRGAYYANH"
     gene            complement(1952..3475)
                     /locus_tag="J8S10_001996"
     CDS             complement(1952..3475)
                     /locus_tag="J8S10_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HAZ9630578.1"
                     /translation="MNNEEEKEKRLTEEAELTADSPKVEKENEKQPTDGKTISGYALK
                     FGQPSKDLGGFVEVITPEALKEVDLSNVFLLYGHDYSKPLASVKAGTLKLNVDDTGLH
                     FEAELTDTTYSNDVYENISKGVVDSMSFGFVLGLDSFDKKEDGTIERSIDKIKALNEI
                     SVVTVPAYDSSNVQVNKRSYESFMSNNQAKQTNNSLESTSKAQKESNNMEKTLIDNEK
                     TELRGYEEYIRSQGEVRDGVTTVNAAAVVPEEVIGEVFDLKRSNYNLAQYATVKTVSN
                     GQGKYPVATNQQAVLATKAELAEIGDIDAEMFTSVDYKVETRAGKIALSNEVVEDSAV
                     NIVQEVKDQLAKLVENTDNKHIMDLLKTFTKKTAATLDDLKQLYNVALDPALNKMVIL
                     NQSGYYHLDTLKDSDGRYILQPDVTAPSGKSLFGMPVVLIADTLFANPKAGTFPMIMG
                     DIAQSIFVARRNQVTTQWEKFDYYSQGLAVIVRNDYKKIDQNASVYIEFTPVVTPKV"
     gene            complement(3468..4643)
                     /locus_tag="J8S10_001997"
     CDS             complement(3468..4643)
                     /locus_tag="J8S10_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAZ9630579.1"
                     /translation="MAFFKARQNTTGDPFLQHVVSIQSDDYTTSFTSVRALRNSDVFA
                     AVRIIASDIASSPIQLVKNNMPQADNELVKLLNEKPNSEMDGWHLKFALAVNMLLNGN
                     SFAEIKRNGEKVEEIHLLPNSSVTVTQLDNGTLSYQIGDKKRRVKSSDILHFKYFTQD
                     GLTGLPPLYALRDELKIQQAGNRTLHNFFTRGVSGSGILKVHKSDLDGSAKNAIREKF
                     EEANGSSSGDNALRTIILDETMDYKTLEINTDVLKLINSNDWNTKQIAKAFGVPIERL
                     GVENEHSSTVQSNLQYIQSTLIHYFNVFVSELDTKLETNIRFNSDQLLETDPETKVKN
                     VLDQVKGSLLTINEGRSKMGLPPMDGGDRLLASLNFTYLDTLEKYQLKEQEGVTPVE"
     gene            complement(4647..4832)
                     /locus_tag="J8S10_001998"
     CDS             complement(4647..4832)
                     /locus_tag="J8S10_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630580.1"
                     /translation="MNFIQVKNFLSNYIHTVLLLLGLVCVLVAITLLTNVYYGLLALG
                     IVLIGVAVMLNTEQKGG"
     gene            complement(4798..6492)
                     /locus_tag="J8S10_001999"
     CDS             complement(4798..6492)
                     /locus_tag="J8S10_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HAZ9630581.1"
                     /translation="MNDYIEKVLSGKLIAPKKIIQACERHISDLERSKSDSFPYVFDE
                     EQATKAIKFIELLPSTDGKAIKMLGFQKFILGSLYGWRTKEGNYRRFNRAFTSMSRKN
                     GKTYIASGMAANALIMEQEPAEARQVLFVSNALKQAKLGYDMLSNSLRNVVKSSKFLR
                     PQLKIMNSKIQHLPSNSFAMALASETSTLDGFAPTTAILDEWHEAKTRKTYNVIKSGM
                     TQQKNGLLCVISTAGLDLNVPMYEEYLLLDRVLKGEEQADRYFIAIWELDDPEEIHDQ
                     EKWIKANPIFESEEIKKVMIPTIQDDVNLALKQNNLNSVLVKNFNLWRQASEDSYMIA
                     EDWQATEVEPQDITGKPVYIGVDLSKTDDLTSVSWIVPLDNGELYCDSHSFVATKYGL
                     QDKEKRDGLPYRELEKAGECSITQLESGIVDYDQVFQFIQDLIQENDLECMGICYDPY
                     NANSLISKAEKANYPMLEVRQGTITLNVPTRTFREQVYEGNVIHNKNTILTHAVNNAI
                     LKTDNNGIQINKSKNSNKIDPIAALINAYVFAMDYFTTTEGAKADNEFYTSEEFSF"
     gene            complement(6489..6962)
                     /locus_tag="J8S10_002000"
     CDS             complement(6489..6962)
                     /locus_tag="J8S10_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HAZ9630582.1"
                     /translation="MGHPKILHDTKGNISSEEKAIRVDAREELFKQQPLINITPPDWM
                     AASARSEWNRIVPTLKKDYPLSEADYGSLVAYCLAFARMKTAEAEIRKSGTFITCENG
                     VKKANPAVRVQSQAMSDLKKQATSLGMTLESRSKLALNKVKNDEPEDPFKELMNS"
     gene            complement(7031..7186)
                     /locus_tag="J8S10_002001"
     CDS             complement(7031..7186)
                     /locus_tag="J8S10_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HAZ9630583.1"
                     /translation="MKVGDLLKNTIVITDKTGKQRTIELPHFGQVTIQMQNGKIIYID
                     KLDKEKF"
     gene            complement(7320..7700)
                     /locus_tag="J8S10_002002"
     CDS             complement(7320..7700)
                     /locus_tag="J8S10_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HAZ9630584.1"
                     /translation="MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGK
                     YFQFYQSRTWRKASYLYRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNF
                     RSLCHAHHNSKTANERQRREKSTL"
     gene            complement(7704..7919)
                     /locus_tag="J8S10_002003"
     CDS             complement(7704..7919)
                     /locus_tag="J8S10_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630585.1"
                     /translation="MHMESIRYFDGEKHIEYSNTQEDVDFISFEEDKITKVNFKDGTC
                     LKIVSPYIEYKSKWEQDDSDERDRFGW"
     gene            complement(7922..8329)
                     /locus_tag="J8S10_002004"
     CDS             complement(7922..8329)
                     /locus_tag="J8S10_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3206 domain-containing protein"
                     /protein_id="HAZ9630586.1"
                     /translation="MLNIISTNKAPNFQYTDEMDRFLMNTLAFSVGLVTEDYSTFDPE
                     VLKIMEEEPDWLQESVAWCQSLVVGSLVDSGNYDDTGELMDEFNCLLNLYDRARQREL
                     TSNEDNLFLNIHDKFLALLLTDDELITNLLEVE"
     gene            complement(8595..10070)
                     /locus_tag="J8S10_002005"
     CDS             complement(8595..10070)
                     /locus_tag="J8S10_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HAZ9630587.1"
                     /translation="MAHKHKLDSILDFPEASEREDNIIELKTWMSRLRCNKDDQIKSN
                     SVVNAELILTNDSNLAGTIAYNEFSGYIHLLKDSPWINRTAGEWEDSFEDALTAYIEE
                     NYNVVFDDNKIHKAVVNVARKNVFNPVKERIEKVKWDQQPRLETLFIDLLGVDDNLYT
                     REVTKRWIVGSVARIYKPGIKFEIVPVLDGPQGIGKSTVPALLYTDDFFTDSLDSLGE
                     KKDDYMQLQGNVIIELGELSSMNKTKIEQIKNFISAKIDKIRPPYGRNVIAWARQCVF
                     IGTSNDGQYLKDDTGNRRFYPLPCKNKPKMNPFKTKDEYFLQVLAEAKVLFDKGQRIY
                     FSPDEDKEVLEIAKDYQEDAKMENPIKEAITKYLEMEIPYKWEEAPAWARRSYYQNYP
                     DSKCNEKNLQHFYNGATMQQEFYLVDSVLTADILEAVFDKQAKDLLNGRSDAETKKIA
                     LIISSIPGWERKQLPKRNKRRGFYNKSNAYENKNRAGKYKK"
     gene            complement(10060..10908)
                     /locus_tag="J8S10_002006"
     CDS             complement(10060..10908)
                     /locus_tag="J8S10_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication protein"
                     /protein_id="HAZ9630588.1"
                     /translation="MANNYQAATELQKSGWSIYPLSPGTKIPIKGSSGWNDATNDSNQ
                     INEWWTEDATRNIGLMLEDHQMVVVDLDQHSETRNGVENYKKLASMYDPFPSTYTEIT
                     PGKGIHFFFKIPDGVIIQQETGAFADIFGRDDKGKSLSGIDIITKGVPIAPTMIISRS
                     VGRAYEPIENVSLNNIAPAPDWLVNLLLKKPQEIKTQYRPVAKTGTAKKLDMIVQGAG
                     EGSRNDHLTKLCGWLLWHGVDNQTLAELIYTANAYNEPPLKDKEVNQIIRSMIKKDLR
                     GKAHGS"
     gene            complement(10945..11307)
                     /locus_tag="J8S10_002007"
     CDS             complement(10945..11307)
                     /locus_tag="J8S10_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630589.1"
                     /translation="MYKTKLLNQLDSLELEEINQGIAELENNIGKTYFGNSFNEKLTV
                     LYVLKKHAEHKIICREINELKNQILTAWLNITDMQEARVKTFNTWVKYQNQLKGAEFV
                     RDGLKYELEQLKLMEVSE"
     gene            complement(11607..12231)
                     /locus_tag="J8S10_002008"
                     /pseudo
     CDS             complement(11607..12231)
                     /locus_tag="J8S10_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350005.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
     gene            complement(12228..12539)
                     /locus_tag="J8S10_002009"
     CDS             complement(12228..12539)
                     /locus_tag="J8S10_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630590.1"
                     /translation="MESTQNKAIEKVLSTILTEDTAAELANLEGKALEETFECLYEQM
                     DYQKLLPQEPTVSGVLRGLNDLVQAEFKERLSIEEYQEILYQQVELLASLLGLELEDV
                     E"
     gene            complement(12583..12876)
                     /locus_tag="J8S10_002010"
     CDS             complement(12583..12876)
                     /locus_tag="J8S10_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630591.1"
                     /translation="MELKIDKLTLDDPAFKIIDDRVVQQVEQTQGTLLSLLEKKYQFP
                     KYMNKAQAAKYMNVSYNTMMQKYVPNGLKLIIVDGVVRISQDECDRFMEEYQK"
     gene            13070..13717
                     /locus_tag="J8S10_002011"
     CDS             13070..13717
                     /locus_tag="J8S10_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAZ9630592.1"
                     /translation="MNGGENVARKKYPEAVETGQRIRLARIEKGLSMEQLGGKLSPPA
                     SKGAVSNWENGYNLPNNTRLKQLSKVLDVSTTYLLNGSYTLRDMHMMPEIKRNVLEKQ
                     LKKTIEKNNSIIDSNLSNAINNIEEDNLTVSQKIYLTNAIKYLKTGSRIEFPDGSTPI
                     AYLAALLNTLLRYDSLINDSEKNTDEKKEYQEFYENDLLKEFTALVTELNKHYSK"
     gene            13778..14923
                     /locus_tag="J8S10_002012"
     CDS             13778..14923
                     /locus_tag="J8S10_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAZ9630593.1"
                     /translation="MATFKQYETKKGKFWLYEAYLGMNKMTGKPDKVRRRGYKTKKEA
                     QLALSRLQVDYDKNGIKKANNETFKEVYDLWLETYKTTVREATFMKTEIKFRKWILPK
                     YGNLRVNEVTVKKAQQIVNSWAETTDQYKVLHSTSKRIFSYAINLGIIETNPLDNVLM
                     PKRTTTKHKEKVKVYSKEQLITLFDYLNSKPETYRNDFDKTLLRFLFYSGVRISEALA
                     LNWSDIDFQENTVTINKTLSQSKNGYKISDPKTDCSAGVLPLDERTISILKKWQINQR
                     KYMLTLGVTDPTMIFCGIYKELITHHAIYARLITICEKAMVPFLGVHVARHTHASMLL
                     DAGATMVEVQTRLRHTKISQTIDCYGHLAKETKEKTVEKLVQHLNID"
     gene            complement(15004..15309)
                     /locus_tag="J8S10_002013"
     CDS             complement(15004..15309)
                     /locus_tag="J8S10_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HAZ9630594.1"
                     /translation="MTEHNHSHDHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(15334..15765)
                     /gene="ruvX"
                     /locus_tag="J8S10_002014"
     CDS             complement(15334..15765)
                     /gene="ruvX"
                     /locus_tag="J8S10_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HAZ9630595.1"
                     /translation="MRVMGLDVGSKTVGVAISDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            complement(15762..16028)
                     /locus_tag="J8S10_002015"
     CDS             complement(15762..16028)
                     /locus_tag="J8S10_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HAZ9630596.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPSYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            complement(16283..17008)
                     /locus_tag="J8S10_002016"
     CDS             complement(16283..17008)
                     /locus_tag="J8S10_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HAZ9630597.1"
                     /translation="MSKKTTKAIVGIVAAVIAGAFGVSTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            complement(17369..17439)
                     /locus_tag="J8S10_002017"
     tRNA            complement(17369..17439)
                     /locus_tag="J8S10_002017"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(17405..17407),aa:Gly,seq:ccc)
     gene            17556..18308
                     /locus_tag="J8S10_002018"
     CDS             17556..18308
                     /locus_tag="J8S10_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HAZ9630598.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            18324..18803
                     /locus_tag="J8S10_002019"
     CDS             18324..18803
                     /locus_tag="J8S10_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter"
                     /protein_id="HAZ9630599.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(19054..20634)
                     /locus_tag="J8S10_002020"
     CDS             complement(19054..20634)
                     /locus_tag="J8S10_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HAZ9630600.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(20627..21370)
                     /locus_tag="J8S10_002021"
     CDS             complement(20627..21370)
                     /locus_tag="J8S10_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9630601.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            complement(21546..21935)
                     /locus_tag="J8S10_002022"
     CDS             complement(21546..21935)
                     /locus_tag="J8S10_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator"
                     /protein_id="HAZ9630602.1"
                     /translation="MKEKENYPVQHATKKRWTTVRYGNSDHYIHYDEILYLMSMPGYK
                     NKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENITSISRVNEIVTFAN
                     GEQLEMGKRSIDKLKNFMQEKIENESF"
BASE COUNT         6418 a         4447 c         3578 g         7529 t
ORIGIN      
        1 ggaagagact gtgaagtcaa cgttttgacc tgattattag agaaacaaat ggcaaaatag
       61 ttcttcatat ttcgccgttt ttcgagcgaa tgccgagggg cagctgattg aacatcgttt
      121 atttggaaaa agggattgtg acaagacgtt tgtcacaatc ccttttttta tatcttatta
      181 attcattctt ttgttctatt cttcttcttc cgccatgaat gagaaaccca tatcaaagaa
      241 ctataaaggt tatcaaaaca gcgtttatga ctaaatgaat tagagttatc tatcactatt
      301 tttcaagcga tttaaaccaa atggcataca atatggcata caaaaacttc aataagccgt
      361 gggggttttt aaatttcttc ttgttcttta aaatcaatga gtggagctac ataatttgaa
      421 tccacttttt caaacgtcac tttttgcatc gacgaatgtt ttctttccca agataacgta
      481 aatagatttg actctggact tataaagtct acttcacctt ctagtattac tttcttatgc
      541 aaatattcct ctaataaata tagacttgct aaagcataca acacattttc caaatttgct
      601 tccttataat ttgaagaacg accatgtttt actctgttat atattttcca ccaatctggt
      661 gtatcttcag gccacccatc tccaaaaggt tttagtgaag tcaatgttaa agaattcata
      721 accctaacac cattatccaa acacattaat tcgctagatt taataacagc tttaaaatca
      781 gttatgcttt tattgctact gctatcaaat ccgcaaagtt ctttgaaaat aatctcacac
      841 tccgaaccaa tcgctagtag tagtttttga tattcaatag agaatgtttt gaaattattc
      901 tcatcgagca tcacaaaatc tgtggtatta ataaactcat tttctaaatg tagataatac
      961 ttccaataaa aatttgtaaa ctctgctttg tccattaaat cacctctttt gaattataac
     1021 aaaaaaaaca cgtccacaac agacgtgttc tttgatttct acacaatcag cttgccaaaa
     1081 ccatccaatc agtcctagca tgcctgtatt aaaattgaac gttcatcatc tatcatcttt
     1141 cttagtccag catgtttgca accacaccta caattttcag tccaacaata gatttcgact
     1201 agctaagtct tgcaaaattc aggcagctaa cccttcattt actaccttaa ttatactaaa
     1261 tacccacaac gtttacaagt gtaatcattc taagaaatct gtttagctat gatcgttgta
     1321 taatctttaa acgccgttcc ttcattgatt gaaataattt tataactctt gtttttccaa
     1381 gctactttca tatcgtttgt tagttcataa tcttgatcgt atcgaataat aaacgtcaac
     1441 gttccttcaa gaatggtacc tacactagca agcacgtctt ttagcatttg tgaacgcaca
     1501 ttagcccaac attcaaatac agtttcttca ctatccacca tctgcccatc ttcatctttt
     1561 acccgttttg tctttttaaa cttgactctc tcagtcaatt catttacatt cttaatgatt
     1621 ggcataataa gcacctctca tttgttgtac taatgcttgt accgttactg gtatccgttc
     1681 gctgctggct tcttgacggt tcaaatacca atgttgagta agtaatgaca ccgccaaatc
     1741 aaattgctga taattatcca tatctttatc cgttgcgcta ctatcaatag cactttttat
     1801 atattcgcct gctgtatcaa tcaattgttg aataaagtca tcatcaatag tgtgatcgat
     1861 ccgcatactt ttttttatgc tatccaaaat taccatttta tctctcctaa tgaaaaaaag
     1921 gcagtgggat aaaccgccgc ccaatatttt tctatacttt tggtgttaca actggcgtaa
     1981 actcaatata cactgaagca ttttgatcaa ttttcttata atcgttgcga acgatcactg
     2041 caagtccttg tgagtagtaa tcgaattttt cccattgagt cgttacttga tttctacgag
     2101 caacaaagat agattgtgca atatccccca taatcatagg gaatgttcca gctttaggat
     2161 tggcaaacaa tgtatctgca atcaatacta ctggcatacc gaataatgat ttaccactag
     2221 gtgctgtcac atcgggttgt aaaatgtaac gtccatctga atctttcaat gtatctaggt
     2281 ggtaatatcc gctttggttt agaattacca ttttatttaa tgctgggtct aatgccacat
     2341 tgtatagttg tttcaaatcg tccaacgtag cagccgtttt cttagtgaat gtttttaata
     2401 aatccatgat atgcttattg tcagtgtttt ctaccaattt cgctaactga tctttgacct
     2461 cttgtacaat attcactgct gaatcttcca caacctcatt tgataaggca atcttaccag
     2521 cacgagtttc tactttataa tcaactgaag taaacatttc agcgtcaata tcaccaattt
     2581 cagcaagttc agcttttgtt gctaacactg cttgttggtt agttgctact ggatatttac
     2641 cttgtccatt tgatactgtt tttactgttg catattgagc taagttataa tttgaacgtt
     2701 tcaaatcaaa gacttcaccg attacttctt cgggaacaac tgccgctgca tttacagtag
     2761 tgactccatc acgcacttcg ccttgtgaac ggatatattc ttcataccca cgcaattctg
     2821 ttttttcgtt atcgattaaa gttttttcca tgttattact ctccttttgt gctttagaag
     2881 tggattctaa gctattgttt gtttgttttg cttggttgtt actcataaac gattcgtaag
     2941 aacgcttatt tacttggaca tttgatgaat cataagcggg aacggtcacg acactaattt
     3001 cattaagtgc tttgatttta tctattgatc gttcaattgt gccatcttct tttttgtcga
     3061 atgaatctaa tccaagcacg aacccaaagg acatagaatc aacaacccct tttgagatat
     3121 tctcatacac atcatttgaa taggtcgtgt cggttagctc tgcttcaaaa tgtaatcctg
     3181 tatcatcgac attcaatttc aacgtacctg ctttgacact agctagtggc tttgaataat
     3241 cgtgtccata taataagaac acatttgata aatccacctc ttttaatgct tcgggtgtaa
     3301 tcacttctac aaagccgcct aaatcttttg acggttgccc gaatttcaac gcatagcctg
     3361 aaatagtttt gccgtctgtt ggttgttttt cattttcttt ctctactttg ggagaatcgg
     3421 ctgttagctc agcttcttct gtcagccgtt tttccttttc ttcttcatta ttcaactggt
     3481 gtaactcctt cctgttcttt taattgatat ttctccaacg tatctaaata cgtaaagttc
     3541 aaacttgcta gtaaacgatc gccaccatcc atggggggta gccccatttt cgaccgcccc
     3601 tcattaatcg tgagaagtga ccctttgacc tgatccaata cattttttac ttttgtttca
     3661 ggatcagtct ctagtaactg atcggaatta aagcggatat tggtttcaag tttcgtatct
     3721 aattcactca caaacacatt aaagtaatga atcagcgtac tttggatata ctggagatta
     3781 ctttgaacgg tgctagaatg ttcattttca acgcctaaac gctcaatcgg tacaccaaac
     3841 gccttggcaa tttgttttgt gttccaatca ttggaattga taagcttcaa aacatcggtg
     3901 tttatttcta atgttttgta gtccattgtt tcatcaagaa tgatcgttct aagagcatta
     3961 tctccactac ttgaaccgtt ggcttcttca aacttttcac gaattgcgtt ctttgctgat
     4021 ccgtctaaat ctgacttatg aaccttcaaa atacctgacc cactgacacc acgagtaaag
     4081 aaattgtgca atgtgcggtt gccagcttgt tgaattttca gttcatcacg taacgcataa
     4141 agtggtggta atcctgttaa accatcttgg gtgaaatatt tgaagtgcaa aatatcgcta
     4201 gacttcacac gtcttttttt atcaccaatc tgataagaca acgtaccatt atctaattga
     4261 gtaaccgtta cacttgagtt aggtaataag tgaatttctt ctaccttttc accgttgcgt
     4321 ttaatctctg caaagctatt accgtttagc aacatattga ccgccaaagc aaactttaaa
     4381 tgccaaccat ccatttctga attaggtttc tcgtttagta acttcaccag ttcattatca
     4441 gcttgtggca tattgttttt gaccaattga atcggacttg aagcaatatc actagcaata
     4501 attcgaacgg ctgcaaacac atcactattt cttaatgcac gaacgcttgt aaagctggtg
     4561 gtgtaatcat ccgattggat tgataccaca tgttgtagga aaggatctcc cgttgtattt
     4621 tgtctcgctt taaaaaatgc catcttttaa cctcccttct gttctgtatt tagcatgacc
     4681 gctaccccaa taagcactat gcccagcgct aacaagccat agtagacatt tgttagtaag
     4741 gtgatagcaa ccaacacaca caccaatcca agaagtaaaa gaacggtatg aatgtaatta
     4801 gaaagaaaat tcttcacttg tataaaattc attgtctgct ttcgctcctt ccgttgtggt
     4861 gaagtaatcc attgcaaaca cataggcatt gattaatgca gctattggat caattttgtt
     4921 actgttcttt gatttattaa tctgaatgcc gttgttatcc gtttttaaaa tagcgttgtt
     4981 cactgcatgg gtgagaatcg tatttttatt gtgaataacg ttgccttcat aaacttgttc
     5041 tctaaaagtt cgggtcggaa cgtttagagt aatcgttcct tgtcttactt ctaacattgg
     5101 gtagttggct ttttcagctt tactgataag cgaattagcg ttatacgggt cataacaaat
     5161 ccccatacat tccaaatcat tttcttgaat caaatcttga ataaactgaa atacttggtc
     5221 atagtccacg attccacttt ctaattgagt aatggaacac tcaccagctt tttctagttc
     5281 tcgataaggc aaaccgtcgc gcttttcttt gtcttgaagc ccatatttgg tggctacaaa
     5341 gctatgtgaa tcacaataaa gttcgccgtt atctagcggt acgatccatg aaacgctagt
     5401 taaatcatct gttttagata aatccactcc gatataaacg ggcttgcctg taatatcttg
     5461 tggttctact tcggttgcct gccagtcttc agcaatcata tagctgtcct cactcgcttg
     5521 tctccataaa ttgaagtttt tcaccaatac agaattaagg ttattttgtt tcaaagcaag
     5581 gttcacatca tcttgaatgg ttggaatcat tacttttttg atttcttcac tttcaaaaat
     5641 cggattggct ttgatccatt tctcttgatc gtgaatttct tcgggatcgt ccaattccca
     5701 tatcgctata aagtacctgt cggcttgttc ttcgcctttt agcacacgat ctaacaataa
     5761 gtattcctcg tacataggaa cgtttaaatc aagcccagcg gtactaataa cacacaataa
     5821 gccgttcttt tgttgggtca ttcctgactt aatgacgttg tacgttttac gagtttttgc
     5881 ttcgtgccac tcgtcaagaa ttgcggttgt tggtgcaaac ccatctagcg tgctggtttc
     5941 actagccagt gccatagcga acgaattaga gggcaagtgc tgaatcttag agttcataat
     6001 tttcagttgt ggtcttaaaa acttactaga cttgaccacg tttctaagtg aattagacag
     6061 catatcatag cccaatttag cttgtttcaa agcgttactt acaaacaata cttgccttgc
     6121 ttctgctggt tcttgttcca taatcaacgc attggcagcc atgccacttg cgatatacgt
     6181 tttcccattc ttacggctca tactggtaaa cgctcgattg aatcgcctgt aattcccttc
     6241 tttagtacgc cagccataaa gactgcctag aatgaatttt tgaaatccta acatcttgat
     6301 tgctttaccg tccgtagatg gtagcaactc aatgaattta atcgctttgg tggcttgttc
     6361 ttcatcgaac acataaggga agctatctga cttagaacgc tccaaatcgc ttatatgacg
     6421 ctcacacgct tggataattt tcttgggtgc aatcagctta cctgatagga ctttctcaat
     6481 gtaatcattc atgaattcat caactctttg aacgggtctt cgggttcatc atttttaacc
     6541 ttgttcaaag ctagttttga tcgtgattct aaggtcatac ctagtgaggt ggcttgtttt
     6601 ttcaaatcac tcatagcttg tgattgaacc cgaaccgctg gattggcttt ctttactccg
     6661 ttttcgcatg tgataaacgt acctgatttt cttatctcgg cttcggctgt tttcattcga
     6721 gcaaaggcta aacaataggc taccaatgaa ccataatctg cttcactcaa tggataatct
     6781 ttttttaatg ttggtacgat acgattccat tcacttctag cgctcgctgc catccagtca
     6841 gggggcgtga tatttattaa tggttgctgc ttgaacaatt cttctctagc gtccacacgg
     6901 attgcttttt cttcacttga tatattgcct tttgtatcgt gtaatatttt agggtgtccc
     6961 atgttgtcct cctttcagac aaaagaaaaa ggaacgtaag caattaagct cacattcctt
     7021 cgtttttcga tcagaatttt tctttatcta atttatctat ataaatgatt tttccgttct
     7081 gcatttgaat ggtcacttga ccaaaatgag gtaactcaat ggtgcgctgt ttccctgttt
     7141 tatcagtaat aacaattgta tttttcaata aatctcctac tttcattata tactttttca
     7201 cttgtgatta caagtgtaat cgttatttgt aattaccctt atgccttttc acaacggtta
     7261 tttgtaccaa aatgagtagg catcgattgt cagtaagttt cacactatgc ccccttaact
     7321 caaagggtac tcttttctcg tctttgtctt tcattggctg tcttggaatt atggtgtgca
     7381 tggcataaag aacgaaaatt agtttcatct aaccgtctat tccaatcatc ttttagttca
     7441 attttgtgat ctacaacatc agctttcctt atcaagcctt cttctaggca atcctcacat
     7501 actggatgat ttaaccgata caagtatgaa gcctttcgcc atgttctact ttgatagaat
     7561 tgaaaatatt taccttcgct ttgctttctt tcttcacgct taattgccgt ttgctttgct
     7621 ttatgcttcc cacaatactt ctgcctataa tcaatcaatg ttttacatcc agcatgatta
     7681 cattgttttt taactgccat agattaccaa ccaaagcgat ctcgttcgtc agaatcatct
     7741 tgttcccatt ttgatttgta ttcaatataa ggcgaaacta tcttcaagca cgttccgtct
     7801 ttaaaattaa ctttagtgat tttatcttcc tcaaaactaa taaagtctac atcttcttga
     7861 gtgtttgaat actcaatgtg tttctcacca tcgaagtatc taatactttc catatgcata
     7921 attattctac ctccaataaa ttagttatca attcatcatc tgttagtagc aaagccaaga
     7981 acttatcatg gatgtttaaa aacaaattat cctcattcga tgtaagctct cgttgtctcg
     8041 ctcgatcata taggttaagc agacaattaa attcatccat tagctcacct gtatcatcat
     8101 agttgccact atctaccaat gatcccacta ctagcgattg acaccacgct actgactcct
     8161 gcagccaatc aggttcttct tccattatct ttaatacttc tggatcaaat gtggaataat
     8221 cttctgttac caatcccaca ctaaatgcca gcgtgttcat tagaaaccga tccatttcat
     8281 ctgtatattg aaagttcggt gctttgtttg ttgaaataat attgagcatt tactttcctc
     8341 cttgattcgt aacacgtggt aacacctacg taacaggtac ccgttaccac tcaatcccaa
     8401 cggggacaag ggttctagcg ttttggtaac aggtaacggg taaaatccag taacattatt
     8461 ccccagcata ttagctaact atttcaaaag ttttaaggaa ataaggtgtt accccgttac
     8521 caaattgctg tatcccttgg ggcagtaagg gtaaactagt aacgggctag gtgttactga
     8581 cccgttacta cccgttactt tttgtacttt ccagctcgat ttttattttc ataggcattt
     8641 gacttattgt aaaatcctcg tcgtttattt ctttttggca gttgcttccg ttcccaacca
     8701 ggaatactgc taataatcaa ggcaatcttt ttagtttctg catctgatcg accattcaat
     8761 aaatcctttg cttgtttatc aaaaacagct tccaaaatat cagcggtgag tacgctatca
     8821 actaaataaa actcttgttg catagtagct ccattataga aatgctgtaa atttttctca
     8881 ttacatttac tgtcaggata gttctgataa taagaacgtc tcgcccacgc tggagcttct
     8941 tcccatttat acgggatttc catttccaaa tatttagtga ttgcttcttt aattggattc
     9001 tccatcttgg catcctcttg atagtctttt gcaatttcta agacttcttt atcttcatcg
     9061 ggactaaaat agattcgttg tcctttatca aaaagcacct ttgcttcagc taacacttga
     9121 agaaaatatt catcctttgt tttaaacgga ttcatctttg gcttattctt acaaggcaaa
     9181 ggataaaaac ggcggtttcc tgtatcatct ttcaaatact gcccatcatt cgacgttcca
     9241 ataaatacac attgccttgc ccaagctatg acattccgac cataaggagg tctaatttta
     9301 tcgatcttgg cactgatgaa gttttttatc tgttcaattt tagttttgtt cattgaagat
     9361 aattctccaa gttcaataat tacattgcct tgaagctgca tataatcatc tttcttttca
     9421 cctagcgaat ctaatgaatc ggtgaaaaaa tcatccgtgt aaagtaatgc tggaacggta
     9481 ctcttaccaa tcccttgcgg tccatccaaa actggaacga tctcaaactt tattcctggt
     9541 ttatagatac gtgcgactga tccgactatc caacgttttg ttacttctcg tgtgtaaagg
     9601 ttgtcgtcta cccctaaaag gtcaataaac agtgtttcca gtctaggctg ttgatcccat
     9661 ttaacttttt cgatacgttc ttttactggg ttgaaaacat tctttctagc cacatttact
     9721 actgctttgt gtattttgtt gtcatcaaaa actacattgt agttttcttc aatatatgcc
     9781 gttaaggcat cctcaaaact gtcttcccat tctccagcgg tacgattgat ccaaggagaa
     9841 tcttttaata ggtgaatgta tccgctaaat tcgttataag caattgttcc agctaaattg
     9901 ctatcattgg ttaaaatcaa ttctgcattc acaacactgt tacttttaat ctgatcgtct
     9961 ttattgcatc ttaatcgtga catccaggtt ttcaattcaa tgatattgtc ttcacgctcg
    10021 ctggcttcgg gaaagtctaa aatactatct aatttatgct tatgagccat gagctttccc
    10081 cctcaaatct tttttaatca tcgatcgaat aatttgattc acttctttat cttttagcgg
    10141 tggttcattg tacgcatttg ctgtataaat caattctgct aaagtttgat tatctacacc
    10201 gtgccatagt aaccaaccgc ataacttagt taaatgatcg tttctactac cttcgccagc
    10261 gccttgaaca atcatatcta atttttttgc tgtccctgtt tttgctacgg gtcggtattg
    10321 agtctttatt tcttgcggtt tttttagcag taggttcact agccaatcgg gagctggtgc
    10381 aatattattt agagatacgt tttcaatagg ttcatatgct ctcccaacac ttcttgaaat
    10441 aatcatagtt ggcgctattg gaactccttt agtgataata tcaatcccgc ttaaactttt
    10501 acctttatca tcacgcccga agatatcagc aaatgcacct gtttcttgtt ggataattac
    10561 accatcagga attttaaaga agaaatggat tcctttacct ggtgtgattt ccgtataagt
    10621 agaaggaaat ggatcataca ttgaagcaag ttttttataa ttctcaacgc cgtttcgtgt
    10681 ttcagaatgt tgatctaggt caactaccac catttgatga tcttcaagca ttaacccaat
    10741 atttctagtt gcatcttccg tccaccattc attaatttga ttagaatcgt tagttgcatc
    10801 attccaacca ctagagcctt ttattggaat tttagttcca ggagataagg gataaattga
    10861 ccatcccgac ttttgtaatt ccgttgctgc ttgataatta tttgccaata aacctctcct
    10921 cctttttcaa aatactggta taaatcattc agacacctcc atgagcttca actgctcaag
    10981 ttcgtatttc aacccatccc gaacaaattc agcacctttt aattgattct gatactttac
    11041 ccatgtatta aatgttttca cccttgcttc ttgcatatca gtaatgttta accatgcggt
    11101 taaaatctga ttttttagct cgttgatttc tcgacaaatt attttgtgtt ctgcatgttt
    11161 tttgagtaca tacaaaactg ttagtttttc attgaatgaa tttccaaagt aggttttccc
    11221 gatattattt tctagttcag cgatcccttg attaatttcc tctaattcaa ggctatcgag
    11281 ttggtttaat agttttgttt tgtacatcta cttatgccct ccagttctta attgatagtc
    11341 gtactcgtca taagcagtga agagatataa cgctaatcct gcaaagatag ctatttttgc
    11401 aattaatggt aataagccga aaattccgcc gattaaaatg cttcctataa ttaagtttcg
    11461 tttcataatg gttccctccg attttttaat atggtataat cggaacaaag aatatcgggt
    11521 tttatcccaa ttaagttgcc tttatcctgt ccgccaagac tgttatggat aaggcttttt
    11581 ctttgttctc gatcatgtta atgctcctaa gttgtctgca attcagcaga acgattataa
    11641 attttctcac tcactgaaaa ctgcaaccca tatttttctt taacagtcat taattctact
    11701 gtctcatcta aaataggttc acgatcaacc aacatttcag gagtcatatc tttctttttt
    11761 accattttgg aatgaccata aatagttgat acagctttat tggctatcac attcgcttta
    11821 atgtagtcta ctggttttgg ttcagtaata gcgtggctta atttagtcat tgcttctttt
    11881 tggtgttctt tgtctagcat gcggaatact tgaaagcctt caagtcctgt ggactggcgt
    11941 agttctttga tgatgtcgaa aatccagtct tgaaatgcct cggcttcttt tttacggctt
    12001 ttgaatgcca tgcggtaaat attttttttc gttgatgatg tttacatctt gtgttctgcc
    12061 caatgaatcg atgaccttac tagtagtaac cccatcttta ggcaaagagt gaatggctct
    12121 agtaacctgt ttaagaccta acgcttccgc aacatctttc gccactgccc accattcatc
    12181 attaatatcg acaaatctta taatgtgtcc gttccaaatt tcagttttca ttcaacgtcc
    12241 tccagttcaa gccctagcaa gctcgctaac aactcaactt gctgatacaa aatttcttga
    12301 tactcttcaa tagaaagtcg ttctttaaac tctgcttgta ctaaatcgtt caagccacgc
    12361 aatactccgc ttaccgttgg ttcttgtggt agcaattttt gatagtccat ttgttcgtac
    12421 aaacattcaa acgtttcttc tagcgctttg ccttccaagt ttgctaattc tgccgctgtg
    12481 tcttctgtaa gaattgttga taatactttt tcgattgctt tattttgtgt cgattccatt
    12541 attatttcct cctattaatc cctttgcccc cacggcttgc gtttattttt ggtattcttc
    12601 cataaagcga tcacattcat cttgtgaaat tcttacgact ccatcaacta taatcaactt
    12661 taaaccgtta ggaacatatt tctgcatcat agtattgtat gaaacgttca tatacttagc
    12721 agcttgtgcc ttgttcatat attttggaaa ctggtacttt ttttctaata atgaaagtaa
    12781 cgttccttga gtttgctcta cttgttgaac aactcgatcg tcaataattt taaaagctgg
    12841 atcatcaagc gtgagtttgt caatttttaa ttccatattt atcccccctc gttagcatac
    12901 atttctatac aaagatttta aaaaaatgca agaggctctt gaatacattt ctatacctct
    12961 tataaactca atataccatc ataccttttc atttgcaaga attttaacat acttttttga
    13021 acttttatgt ttcacacata tttaaatcgt gatatagtag agaaaatata tgaatggtgg
    13081 tgaaaatgtg gctagaaaaa aataccccga agcagtggag acaggacaaa gaattagact
    13141 ggctagaatt gaaaagggac tctcaatgga acaacttgga ggtaaattat ccccaccggc
    13201 cagtaaaggt gccgttagta attgggaaaa tggctataat cttcccaata acaccaggct
    13261 taaacaactt tcaaaggtat tagatgtatc cactacctat ctattaaacg gatcttatac
    13321 attaagagat atgcatatga tgcccgaaat taagcgaaat gtgcttgaaa agcaattgaa
    13381 aaaaactatt gaaaaaaata actctataat tgattctaat ctttctaatg ctatcaataa
    13441 catcgaagaa gataacctga ctgtctcaca gaagatttat ttaacaaacg caataaaata
    13501 tcttaaaaca ggatctcgaa ttgaatttcc tgacgggagt accccaattg cttatctcgc
    13561 agctcttcta aatacgcttt tacgatatga ctcattaatt aatgattcag aaaaaaatac
    13621 agatgagaaa aaagagtatc aagaatttta tgaaaatgat cttctaaaag agttcacagc
    13681 tcttgttact gagctaaata aacactattc aaaataataa taaactgcct cctccaaccg
    13741 cccccacggc ttgctacact atggagggaa aactattatg gcaacattca agcaatatga
    13801 aactaaaaaa ggtaaatttt ggctctatga agcctatctt ggaatgaaca aaatgactgg
    13861 caaacctgat aaggttcgta gacgaggtta caaaacaaaa aaagaagccc agcttgcctt
    13921 gtcacgcttg caagtggact acgataaaaa cggtattaaa aaagcgaaca acgaaacgtt
    13981 taaagaagtt tatgacttgt ggctagaaac atataaaacc actgtccgag aagccacctt
    14041 catgaaaact gaaatcaagt ttagaaagtg gattcttcca aaatatggaa atcttcgtgt
    14101 gaatgaagtc acggtaaaaa aagcccaaca aattgtaaat agctgggctg aaactactga
    14161 ccaatacaag gtacttcatt caacttctaa gcgtattttt agctacgcta tcaatcttgg
    14221 gattattgag actaatccac tagacaacgt attaatgcct aaaagaacca ccactaagca
    14281 taaagaaaag gtcaaagttt acagtaaaga acaactgatc accttgtttg attacctaaa
    14341 cagcaaacct gaaacttatc gaaacgactt tgataaaacg ttactacgct ttctctttta
    14401 tagcggggtt aggatcagtg aagcccttgc attgaattgg tcagacattg attttcaaga
    14461 aaatacggtc accatcaata aaacactaag ccaatccaaa aatggctata aaatcagtga
    14521 tcctaaaact gattgtagtg ctggggttct tccactagat gaaagaacaa tttctatatt
    14581 aaaaaaatgg cagattaatc agcggaaata tatgctgaca cttggtgtaa ctgatccgac
    14641 tatgattttt tgtggtatct ataaagaact aatcacacac cacgctattt atgcaagatt
    14701 gattactatt tgtgaaaaag ctatggttcc atttctcggt gtgcatgtag caagacacac
    14761 tcatgcttca atgctcttgg acgctggagc tactatggta gaagttcaaa ctagattacg
    14821 gcatacaaaa attagtcaga cgatcgattg ttacggtcac ttggcaaaag aaacgaaaga
    14881 aaagactgtt gaaaaattag tacaacactt aaatattgac tagatggcat acaatatggc
    14941 atacagtaaa aaataaaaaa aggagaaacc ctatcatatc aaggtttctc ctagctttat
    15001 agtctattct tcttcttccg ccatgaatgt attgaatact tcttcaatca tgtcccattc
    15061 tgcgtctgtt tcgatttgtt ctaactcgcc ttctgttcca tcttcgtttt cgatgtatgc
    15121 ataagcttgt aattctacat cttcatcttc tgaaacacca gcaggatata aaagaacata
    15181 gttacgtcca aattcttctt gtccgtcaac tgttagtagg atttcatata atgtttcatt
    15241 tccttggtca tccaccaatg tgatgtgttc gtgtccttca tggtcgtggg aatggttatg
    15301 ttctgtcata agattacctc ttttctttta ttattaaaat aattgcttac ctgagccgtc
    15361 taaataattt tgtaagatca tcacagctgc taatttatcg atgacttttt ttcgtttggc
    15421 tcttgaagta tttgcctgct ctactagcat acgttctgcc tgaacagtgg ttaatcgttc
    15481 atcttgataa tcaactggca aggagaatag ttctttgatc ttttctccgt atgacatgga
    15541 agcttctgcc cttggtccga tggaattgtt catattttta ggtaatccaa ctacaaaccg
    15601 gtctacttca tattgtgcta ctaattcctt caaccgatca aagccaaact cttcttctgc
    15661 ttcattgatc cgaatgatct ctactccttg agctgtccag ccaaaggggt cactgatagc
    15721 aacacctact gtcttagaac cgacatccaa gcccattact ctcataaatt cactccatga
    15781 tttgagaggt agtccttgac aattacttcc atgatctcat cgcgttcgtg acggcgaatc
    15841 aaatttcgag catcacgata acgaggaatg taggacgggt ctccagaaag caagtagccg
    15901 acaatctgat tgattggatt gtagcctttt tcttccaaag cccgataaac aatcgctaat
    15961 gtttcgctca cttctttttt gcgactatcg tcaaaaccaa aacgtacggt ttcatctgta
    16021 aaacccatga ttctacacct ctttcccgca aggtaattcc agcttacctt ctacaacctt
    16081 attttactcg aagaaaggga aaactacaaa caaatattcc aaacttccga ataaattaag
    16141 aaacactatt tgtatgtttt tttccttttt tctgtagctt tatcaaaagt actcttttca
    16201 taaagtatac gctatatttc tttgaatgta tgtttttaca caattttttc ataatattca
    16261 taaaaaattc gaatagctgc tactaatttt ttgtttttgt tgcttgtcct gtctcataat
    16321 tgatcgtgta gccatcttga acattgtaga taaagacatt gaattcaatt tttttgtctt
    16381 caatgctttc tgcttccaat tgcactcccc tggctaccag ttcattcccc tcaaaatgag
    16441 gagtgacacg gtagcgtaca tgatgatttg tttctttgat atatgccgca atatcatttt
    16501 cgtgagcaag catgtatgga gcattcaacg aacgtgtccc tgtcatcaag tttttaatgt
    16561 tgttattttg accagtcagc tggaaaccaa ttaaatggct gcgattatat aaccattgcc
    16621 cgtcacttaa tttcttttgt ttccaacctg tcgggtcaat atacaaaggc tctctctttt
    16681 cagtagggaa caaatctttt ccaagcatag cattggcttg tcctactctg ttcaatttat
    16741 caatatttga atagctttcc catgttcctt tggaaaggct aagatcctct tttgtaaatt
    16801 ccggctgatt cccattgatt tctatttctt gatgttttcc atcatattct ggcacatccg
    16861 ctacttgaga agcttgtggt gtggaatcaa aaatagttgt aatctgctga aagatatctg
    16921 aatctttttg tgtggtggaa acaccgaatg cccctgcaat cacagcagcg acgatcccca
    16981 cgatcgcctt ggttgttttt ttgctcattt ctttactcct ttactaacag ctccctaaat
    17041 cttaacatat gttcccctat aaataaatac tagaaagaaa tagaaacagc aaaaaataaa
    17101 acctgtttta agatggctta aaaatacaaa aaagagacgg attcctcgtc tctaatcagt
    17161 caccactcta tctgtaaggt atttattatt attcaaaaat tttcttcata ctcaagacaa
    17221 tacactgatt tcacaaccgc ttggtaaacg gtgcgcaaaa gcttgcatct gcggtaataa
    17281 gtccatccaa gttaaaaaca taagaagttg tttttgcttg gctgttctta ttacttgttg
    17341 cagagcagct ttttcacaac ctattttaag cgggtgacgg gaatcgaacc cgcgacatca
    17401 gcttgggaag ctgggatttt accactaaac tacacccgca atacaaaaac agtatacgcc
    17461 tcttttattc cttcctcaag tttttttatt ctttacgctt ctggtatgtt ttgtagtaaa
    17521 ataaaactaa tcaatcaatt attggagaag atgctatgac gggaaaagaa ttagatctgt
    17581 tgctggacac ttgtttactc gctgggaaaa tcatgatgga aagcaatgcg gagatgtatc
    17641 gggtagaaga tacgatgagt cgaattgctt tagcttctgg aaatttccgt ttggtcagct
    17701 atgtcactca aaccggtctc tttattggtc ttgatcgtac ctcgaccatc cgaatggaac
    17761 aaattaccaa ccgttcgatt aatttagaaa aagtagtaaa agtaaatgat ctttcacgta
    17821 aatatgttgc ttcagagcta acattagaag aactttactg cgaactgcaa gcaatcgacc
    17881 gagaccgttc tttctttcct gtctggttgc aaatcgttag cgcggcagtg atcagtggaa
    17941 caattatggt gttatttggc ggaaagatga ccgatttacc tgtgacttta gtcattggag
    18001 gattgggata cgcagcttat ctatatagtt tgaaattttt tagaatcaaa tttttatcgg
    18061 aatttttatc ttctttattg attggcatag ccgctatcta cagcgtacgt tttggcttag
    18121 gaagcaatca ggatctaatc attatcggat gtgtgatgcc tttagttcct ggagttcaaa
    18181 ttacgaacgc tatccgtgat ttgctagctg gacattatgt ctcaggagtt tctcgcggaa
    18241 cagaagcgat gatgactgct acgatgatcg gttttgcgat tgcttttatt ttccagcttt
    18301 tttattagga aaggaacaca agtatgggga cgatatttat tcagttttct tttagttttt
    18361 tagcgactgc ggcatttgcc gttattacaa atgtacctag gcgttcattg atttgttgtg
    18421 gtctttctgg tgcttttggc tggatgatct actggatctg tgttcaaata ggcggatctg
    18481 ctgcttttgg ttcattgctt ggttctttag gagtagcatt catcagcgat cttttctcta
    18541 aacgtttgaa aatgcccgta acgattttca atattcccgg gatggttcct ctagtccctg
    18601 gtggtttagc ttatcaagcg gttcgaaatc tcgttactga atcctatcga gaagcggctc
    18661 attatgcggt ccaagcaatt atgattgctg gagcaatcgc tttaggtctt gtattatcag
    18721 aagtctttaa ccataacatc cgtaatttca aagtaaagcg tgacgcaatc atgatgaaac
    18781 gaaaaaaacg gctttttaaa taaacgaagt gtaacaaaga aaaggttgtg aaagagacgt
    18841 tcagccttga gcgatgacaa aatatctcac aaacattgcg acaagtaacc gcaggagcaa
    18901 taagaagtaa ttatgagtat taaaaaaagt tttgtaaaaa tagcttctca catttttaca
    18961 taaaattgac ttaatactga gaaactgact tttgaacacc ctctatctgt aaaaaagggg
    19021 ctgcgacatg atttttgtca cggcccctct tctttattca aattttttcc aaaacgttcg
    19081 ttgataataa acgatccata gagcggaaag tattagaact aaaccgatca caggaatatt
    19141 cactaaccaa aatggataaa acaaagccaa cattccgtat aagacgataa gaataatact
    19201 gatgatcaat gaacccatca tagttgcgac taaacccaaa cttcctgaac ctctgttaaa
    19261 taattggtta atattggtcc agttcagcag cagcaaccga taatctctag cgaaataacg
    19321 tagtgacaat aagtagcagc cgaataaaga accaaatagc aagctaggga taaaaaacaa
    19381 aggcagctga aaagacagtc cgcttaataa tgcgatccca ccagttaaaa aactctgcaa
    19441 tatccatccg aatctgaact tttcttttaa atattggttc atagagattg gcaaagaacg
    19501 gataaacaga aaattttctt gatccaaaga aataagattg ctgataaaag aagtctgatt
    19561 aactgttaag aaagccaatg cgatccctac caggaaaaca acaccgatta acttattatc
    19621 taaatcagtt aattttattt cgcctcctag ggcaaaagca agaataaaaa tgattggagt
    19681 taacaaggaa gaagaaagaa cttgcataat caaattaggt tcttttacta attgagcatt
    19741 gtaactaaat aaaagctgat gcacattttg gttcttttta tgggttcttt ttattttgaa
    19801 ctcactgttt gaatcagtca gttgctctgt aagctttggt actatcagct gttttacagc
    19861 aaggaaaaat cccagagccg tgatagctag tattccccaa cccaataaac cttgttgaga
    19921 aagtggctga ctggcagcat catagaatgg caataatatc gaaatcggat gccgatctgt
    19981 taactcattt tcaatagtcc ccgtttgatg attcatccac atgattccag caaatgcgat
    20041 cagcatcgag ctgccaagca agatactaga aactgttttt ctatgttttt taaacactgc
    20101 tgttcgagcc aaaccaaaaa caatcaaact agccagacaa aaaagaataa tcaaaaatag
    20161 agaaaacaaa aggattgaga taatgatagt aagcaaaatc cctagatcag ctcgccatcc
    20221 ggttaaaata aacatgacta gaagcggaaa aacaaaagga atgatggtca aagcaactac
    20281 caaaatcttt gctgaaaaaa cctgttcttg tccaaaaggc agaggcaaaa atacttgcag
    20341 gtcatttcct tcaaaaaaga tattataaat gactgatata ctttgagtta aacctaacat
    20401 accaaaaagt gccacgtaat aagtaaagaa acctggcaat ttaacaaagt tcatagcaaa
    20461 catagcaaat ccgtaaatca gtaaaaaaat cagccctgaa aaaagatttt gagacaaaag
    20521 atagatagtt aatcgctttc ccttttttcc tttctctctt gctttattcg tgagctgtgg
    20581 attaacatat aaaagattaa ctcgaattaa ttctaataat tgtcgcttat acatacggtc
    20641 catctcctgt cgcttgcctt ccagccattt tcaaataaat cttttctagc gtttcatcag
    20701 gtgagccatt caataattca ctaactgccc cctgataaat caattcacct ttcttcaaaa
    20761 tagccagttt atcgcataac tgttgtgcgg tatccaatac atgtgtagaa aaaatgactg
    20821 tttttccttt tgcggcatga gccttcatca tttctttcaa atcaaatgct gcttgaggat
    20881 caagtccttg caaaggttca tccaataccc aaatatctgg atctggcagc aacgtgccga
    20941 tcaaaatcgt tttttgacgc attccatgtg aaaaacttgc gattgtttca ttttgatgac
    21001 tatacatatc aaaaagcgct gtcaattctg ctaaacgctt ttcttttttt tgtgtgtcta
    21061 attcataggc agctgaaatc aagtcccaat attctccagc cgtcaattgt aaaaaaatat
    21121 ctggggaatc aggcacataa ccgatttttt gtttgatact caatcgattt tccgtcaatt
    21181 tcattccatc tactaaaatc gttcccgatg atggttcaat aatactaact aaacttttaa
    21241 tcgtagttga ttttccggca ccattatgtc ctaaaaatcc aaaaatttcc ccttgtctta
    21301 tcgagagaga caagtctttt aatgcttgtt ttttcccgta acttttactt acattgatga
    21361 attcaatcat ttctgtactc cttttgtttg ttattacttt ttattgtacc cttcgttatt
    21421 ggtggagtaa atgtcaaaaa gagtgcataa caaaaaagga tagaaacgac taggctgcta
    21481 cttgggttgt tctcttctac aggaaaacac tcttctaaca ggtaagatat gagtctttgt
    21541 tttctttaaa atgattcatt ttctatcttt tcttgcataa aattctttag tttatcaata
    21601 cttctctttc ccatctctag ttgttctcca tttgcaaatg ttactatttc gtttactctg
    21661 ctaatagatg taatgttttc agtattaatg atataagctt ttaaatcttt acataaatac
    21721 tcatattcga gtgatttttt atatttttta attgtgccgt ttacgagaat ctcttcatct
    21781 ttcaatacta ggcctatttt atttttataa cctggcatgc tcattagata aaggatttca
    21841 tcgtaatgga tatagtgatc gctattacca taacggacag ttgtccacct ttttttcgta
    21901 gcatgttgaa caggatagtt ttctttttct ttcaataagt aactttggat gcttttttta
    21961 tttttttcat aa
//
LOCUS       DADQDV010000053        21316 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.053, whole genome shotgun sequence.
ACCESSION   DADQDV010000053 DADQDV010000000
VERSION     DADQDV010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 21316)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21316)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21316
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.053"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..506)
                     /locus_tag="J8S10_002023"
     CDS             complement(<1..506)
                     /locus_tag="J8S10_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAZ9630603.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSS
                     SYCEHCRSVRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQVILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSM"
     gene            779..3250
                     /locus_tag="J8S10_002024"
     CDS             779..3250
                     /locus_tag="J8S10_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAZ9630604.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(3353..5089)
                     /locus_tag="J8S10_002025"
     CDS             complement(3353..5089)
                     /locus_tag="J8S10_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HAZ9630605.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSGFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(5086..5790)
                     /locus_tag="J8S10_002026"
     CDS             complement(5086..5790)
                     /locus_tag="J8S10_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAZ9630606.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            5921..6424
                     /locus_tag="J8S10_002027"
     CDS             5921..6424
                     /locus_tag="J8S10_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HAZ9630607.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            6384..6722
                     /locus_tag="J8S10_002028"
     CDS             6384..6722
                     /locus_tag="J8S10_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HAZ9630608.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            6743..8161
                     /gene="ffh"
                     /locus_tag="J8S10_002029"
     CDS             6743..8161
                     /gene="ffh"
                     /locus_tag="J8S10_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HAZ9630609.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            8273..8851
                     /locus_tag="J8S10_002030"
     CDS             8273..8851
                     /locus_tag="J8S10_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HAZ9630610.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            8855..9376
                     /locus_tag="J8S10_002031"
     CDS             8855..9376
                     /locus_tag="J8S10_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAZ9630611.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(9455..10009)
                     /locus_tag="J8S10_002032"
     CDS             complement(9455..10009)
                     /locus_tag="J8S10_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAZ9630612.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            10262..10537
                     /gene="rpsP"
                     /locus_tag="J8S10_002033"
     CDS             10262..10537
                     /gene="rpsP"
                     /locus_tag="J8S10_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HAZ9630613.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            10549..10800
                     /locus_tag="J8S10_002034"
     CDS             10549..10800
                     /locus_tag="J8S10_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HAZ9630614.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            10925..11716
                     /locus_tag="J8S10_002035"
     CDS             10925..11716
                     /locus_tag="J8S10_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630615.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            11886..12407
                     /gene="rimM"
                     /locus_tag="J8S10_002036"
     CDS             11886..12407
                     /gene="rimM"
                     /locus_tag="J8S10_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HAZ9630616.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            12397..13158
                     /gene="trmD"
                     /locus_tag="J8S10_002037"
     CDS             12397..13158
                     /gene="trmD"
                     /locus_tag="J8S10_002037"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HAZ9630617.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            13294..13641
                     /gene="rplS"
                     /locus_tag="J8S10_002038"
     CDS             13294..13641
                     /gene="rplS"
                     /locus_tag="J8S10_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HAZ9630618.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            14014..14676
                     /locus_tag="J8S10_002039"
     CDS             14014..14676
                     /locus_tag="J8S10_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630619.1"
                     /translation="MKQNDGRIIWKNQSELKLILTINEFIEKHGITSSRQYQKKLSEN
                     PNSAPSMWFINKKYGSWENLLISIGRENTGYGKWARMSEQELLEIVEAFIKCEKITSQ
                     RMYEQKSVGKNIPSLSTIKKMLGDIRPLFKEKNDGSRFTDFELLLELKNEIIRLKLQD
                     DLSMTKFRKLVQSPKLPSVDTIMKRTNKNWEELMAEIGFDYRRIKIYKQRNNLSKTKK
                     TK"
     gene            14755..17982
                     /gene="fss3"
                     /locus_tag="J8S10_002040"
     CDS             14755..17982
                     /gene="fss3"
                     /locus_tag="J8S10_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HAZ9630620.1"
                     /translation="MKKPRFKNWRLLATLSLLCQTIGGSLGPTIAFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGVKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSEKAKLVSVLWKEAGTDVDTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     ESKINQAIADYQKKPSFHNSTVKTVLGQSTTVTDTNGLNLSEFDEVVENIANIDYRVN
                     GNQLVITPNANSKESGELTLKKSANTGTPVAYKMAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKETGNVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGAKVTIT
                     EKSVPAPYTIDTTPITATIKSGETISVTSKNTREKGQIILNKMGVETGTDLWNDKYSL
                     AGNTFAIRKDSPTGEIVQEMTTDEKGHAETPKEIANALELGTYYVTETKASNGFVNTF
                     KPVKVELNYVNQTVALVTSNVKGQNQEITGETTLTKEDKDTGNETQGKAEFKGAEYTL
                     FTAKDGQAVKWSEAFKPELVKGTKASDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYTLDETKYPVSIKKVDDNEKNAVITRDVTAKEQVIRFGFDFFKFAGSAAGTAETGF
                     NDLTFKVSPLEGTSEITGAEDEAITAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKADYTKSEYIFTITEKGQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLGTWKDGGKELTDLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     EATKAAQEKDEKAKPVVIAETTATLANKEKTGTWKILHKLTAEQVLDKTIVLFNYVYE
                     NKKPYEAGDDPVAKDASLNNQAQTVNCTVERHVSIQTKAHLEDGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDNTTKEIWKSGKIDYEVNDKEFTKTVLAEKVDT
                     SKYPEGTSFTFKEINYGKDGNINGKHNEDLKEKTQTLTPKKVPTTPSAPEQPEIPTVP
                     SDSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            18096..18410
                     /locus_tag="J8S10_002041"
     CDS             18096..18410
                     /locus_tag="J8S10_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAZ9630621.1"
                     /translation="MELKFVVPDMAETFGKIRYAGEGEVLTEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            18423..18797
                     /locus_tag="J8S10_002042"
     CDS             18423..18797
                     /locus_tag="J8S10_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAZ9630622.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIMDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPDQGNSTNQNEGKK"
     gene            18807..19151
                     /locus_tag="J8S10_002043"
     CDS             18807..19151
                     /locus_tag="J8S10_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HAZ9630623.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLTKALTYDEKMFLIMHQGLL
                     EVGNDVEEDFDVLNWLGEEESFFMVIEVNESLCREAETVLEEIGVEMPDAIEVFLKQL
                     VETKQLPIAVND"
     gene            19222..20574
                     /locus_tag="J8S10_002044"
     CDS             19222..20574
                     /locus_tag="J8S10_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HAZ9630624.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQELRQFDI
                     SKLSLSTIEIVRSIKDLIYLLGSLVLSGSTMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTKETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDIIANRIGIDEVVAESGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFVLDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMTRSKAMKEMPNYKTGENYAFLGLPPNFLIFDEYVVYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVDKKFFMKRIKGRGYVDTGGSVISEFYTPLVPKGYDFLREISDIGGLNVNTEG
                     "
     gene            20634..>21316
                     /locus_tag="J8S10_002045"
     CDS             20634..>21316
                     /locus_tag="J8S10_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HAZ9630625.1"
                     /translation="MTFLDLFAGIGGFCLGMEQAGHQCIGFCEIDDFARQSYKAIHDT
                     SKEVEMHDITSVSDEFIQSLGPVDILCGGFPCQAFSIAGKRQGFSDTRGTLFFEIARF
                     AAILQPKFLFLENVRGLLNHEGGATFETILRTLDGLGYDVEWQVLNSKAYVPQNRERI
                     FLIGHSRDACTEQVFPIIGSSPTSDQNIRNLLNINPSNRGMGGQVYGSDDVAPTLTGD
                     EGIKIALPV"
BASE COUNT         7089 a         3822 c         4497 g         5908 t
ORIGIN      
        1 ttcattgatt tgaactcatc catacacaac accgtcggaa ggaagttcat acgtggctgg
       61 taatgcttcg ttgcttcacg caagatccgt gtcaccgtcc catccgagac gaagtacttc
      121 ttagcgatta gtttacgtga ttgattttcg tacagttcca tgagaatcac ctgcttcagt
      181 tcctttgtta gttgatgatg ttcatcaact aagtccgttt tcgcagaaaa ggtccttcca
      241 caatcatggc agagaaaacg ggtacgtttt aattctaaaa tagttaactt ttctttgact
      301 ttcaacatct gagtgcgtgt cgtataggaa ccgttgcgga taatacgaac cgatcgacag
      361 tgttcacaat aggaagaaga gtcatccaat tttcctttaa taaactgcgc ttgaacgcct
      421 ttatattctt tttcaatcag ccattcttca tcaaaaaata aatgtttatc tgttaatccg
      481 agtaattttc tagtatgatt atccattgag agactccttt ggtaggatga cgttttggtc
      541 gactaaattt taccaaaagt gagtctcttt ttgagttgaa acgaagaaaa agtgttagta
      601 gaaaatcgcc ttcgattttc caccaacaca aaatattata gaaccctttt tttttgctat
      661 atgacaggaa tgaaaggtgt ttgcaagctt aatgtgagga acactttcca tatctgttct
      721 atactggata ggagaagttt ggaaatatcc agaaaacgaa atcaatcgag gtagccacat
      781 gaagaataaa tggataaatc gaagtaaaaa aaagaaagta acacaaagat catcagataa
      841 agtcatccgt ctttttccat cgtataaaga aggattaacg gcagatcaag tcaaggaacg
      901 aatagaaaaa ggtgcagcaa ataattcagt cgatcccaca ttcaaaacaa atcagcaaat
      961 cgtattggaa aacatattta cgtatttcaa tttgatcttt cttatcttag ccattttgct
     1021 ttgtttagta gaatcctata agaacttgac ttttttacca gttatcatag ccaatacagg
     1081 aatcgccatt tttcaggaaa ttcgatccaa aaagatcttg gacgaactaa atgttttaaa
     1141 tacagcaaaa gtcaatgtca tacgagacgg gatagaacaa acaatagata tagaagacct
     1201 tgtaatagat gacattgtta ttttagagac tggatatcaa attccagcag atgcagaggt
     1261 cgtggaaggg aaactgcaag ttaatgaggc tttattgaca ggcgaagcag atgaaataac
     1321 caaagaaata ggtgatccat taatgtccgg cagtttcatt gtttccggaa aagcttacgc
     1381 ccgattagac aaagttggag cagattcgta tatttcccag ctgacagtca aagccaagac
     1441 aatgggagaa ggagaacagt cggagatgat tgcttctctt aatcaattga tcaaatggat
     1501 tgggatcatc attattccta tcggtatcct gcttttttct caaagttact tttttaatgg
     1561 aaacacgatc aaagaaagtg tcgttgcaat ggaagcagca ttgatcggta tgatacctga
     1621 aggactgtac ttgctgacga cgattgcatt agcattaagt gcgactaaac tagcaaagca
     1681 aagagttctt ttacacaata tgaaaagcat tgagacattg gcaagggtaa atgtcctttg
     1741 tgtagataaa acaggaacga tcacagaaaa taaaatgtct gttcaaaaaa tgatcgtctc
     1801 taaaaaacaa gaaataatca gtcagtcaga tcaattggaa gcatgcattg ctgactatgc
     1861 aaaagcgatg gcaggagaca atgcaacaat ggaagctgtt aaagcatatt ttacaaaaac
     1921 cactgatcaa tcctatcacc atgttattcc tttttcttct gtccaaaaat tcagcagtgt
     1981 agcgttggca gacaaggtgt atgttttagg agcgcccgaa atggttttgc gcgatcaatt
     2041 gccggaatat gcggaagagt ttgtttcttt cgctgaaaaa ggctatcgcg tgttggtctt
     2101 tggtgtgtac gatgggattc ttgaagaacc agtattgaca gaagcagtca caccattagg
     2161 ctatattctg attgctaatc ctatcagaaa agaagcaaga gccacatttg attacttcaa
     2221 aaaacagcaa gtagccatca aagtgatttc tggagataat ccgctcaccg tatccaatgt
     2281 agctgtccaa gcagggattt cacatgctga tcagtacgtt gatgcatcta aattatcaga
     2341 agaagaatat gaagcagctg tcgaaaaata tacagttttt ggacgcgtca agccagaaca
     2401 aaagaaaatc ttcgttcaat tgataaagcg taacaataca gtagctatga caggtgatgg
     2461 cgtgaatgat attctagcca tgaaagaagc agactgcagt atagcgatgg cttccggaaa
     2521 tgaagccgcc atgcaggcct cacaagtggt cttacttgat tctgactttt cacgcatgcc
     2581 agaagttgtt gcagaaggac ggcgcgttgt gaacaatatt gagcgatcag ccagcttgtt
     2641 tttagtgaag aatattttct cctttttgct ctcactgttt tcagtgatct ttgctctgac
     2701 ctatccttta gaaccatcac aaatcacatt gattagtttg tttactatcg gacttccatc
     2761 tttcttgctt gctctagaag aaaacaaaaa gcgaatcaga gggaaattca tcatgaatgt
     2821 gatggaaaaa gctgtgccag gtggactaac agatatgatc gtagtcggtg cgttggtgat
     2881 ctgcggggtg actttgaatc taaataaaac agatgtttct acagcatcta ccatgctttt
     2941 gattgcagta gggttcctcg ttctctataa aatctgttca ccgctgaata aattcagaag
     3001 tcagatcatt cttttctgtg ctagcggtaa ctttttttcg gtcatctttt tgcataagct
     3061 gttttcaatc accggtatct cagctgtatc acttttgctg ttgagcattc tatttttctc
     3121 ggcagattcg atttttaggc atttgaccac attggtagaa tatttgtttg aacgtaaaaa
     3181 tgaaaaagag caaaagccgt ttagtcgcgt agctaaaaaa tttctatcga tatttaaacg
     3241 agaaaattga cgaaaagtat ctcaaaaaag agtaaaaaag aacaaccact cgtgtatctt
     3301 tcgaagcagg atgagtcatc caactttaaa acgcacgagc agttgctctt ttttacattt
     3361 tcggaatggt aacggtgaaa gtcgaacctg ttccaagatg actgtctaca gtaatcgtac
     3421 cattaaggag ttgcacgtag tcttttacaa tcgctaaccc taatccggtc ccgcctgaat
     3481 gtcggcttcg cgccttgtct acgcggtaaa aacgctcaaa gatccgttcc tgatcctcaa
     3541 tgtcgatacc tataccaaag tcttggacag aaaacgatag atcatctgtt gcctgatagc
     3601 ggataataat ctcgctgtcg ctttttgaat attggacagc attttcaatt agatttttga
     3661 taattggata aaggatatct gttttagtag taaatggttc gttctttcca atcaatcgaa
     3721 tcgtcaaccg tttcttttcg atgattggct gataattttg aacgatttgc tggaaataag
     3781 gttctgtata aattgtctgg atctcgtaag aattctcgcc atcttttgac agctggatga
     3841 tttcccgaat cagtttatct aaccggatcg catctttttg catgatctca agaaaagaag
     3901 tcagagtttg cgggtcatct tttgcaccat ccagtaaagt ctcggtaaaa ccaatcagtg
     3961 aagtcacagg agtttttaat tcgtgagaga cgttgccaac gaaatccttt tgtagctttt
     4021 ctaaacgtcg cactttcgtt aagtcatacg ccacccctag aatctgtccg gtaccttctg
     4081 aattagtaaa gtagcgcaaa ctcaagtcta atgtctgccg accttctgta agggtgatct
     4141 cctgatggat cagcggatgc tcaggagtca cttgatgaat cagctgaatg agttttggct
     4201 cttgaatgac ttctgtgtac cgctgttcag gttgatagct taccacgttt aaatgtagct
     4261 gcatctttgg attaagcagt agtaaacgag aatcagcatc atcaatcagg aatacgccaa
     4321 tcatcagttc gttcagtaac gtatataatt gctcttctgt ggtagtacac gcccgataca
     4381 tcttactcat ttgttcgctc aacgcattaa tcgtctgata caattcttcc cattgatcgg
     4441 gtgtttgcat gattacttcc gcctgattag gattttgcac catttttttt agtacgggca
     4501 gcacggtttt caatggctgg tttttttgat agatcagata atagatcatt cctgcaagaa
     4561 caaggaagaa agacagaaag aagaaaaaga cccaacggcg aaaactctca gttctcggta
     4621 aaaaaccgct tgtcggttct gcgatacgta aaatggcttc taactggcca ctttttttga
     4681 ctggtaatgc gacatataaa agatcctcat tcaaagtagt acttttgcgc aaagcgctac
     4741 ctaggttccc accattcaat acggctttga tttcgggacg ggagtttcgc tgttcattca
     4801 atgtttcatt gtttgtgtca aataagatct ttccagtagc atccattaaa gtaatccgtt
     4861 cgttcgactg atggacgaat tcttccaaag cagttttgtt ttgcgctgct tggaggtttt
     4921 cgacatctaa ttgccggatc agcagttgtg ctttttttgt caggtagctt tcttgctgtt
     4981 ccacgatctg ctgttgaaaa taatgggaaa tcaattgcca gccaccaaaa aacaaactaa
     5041 ctaaaagaat aagaaagaag agacgttcat aaattttttt ccatttcatc gtttgggttc
     5101 ctgaaactta tagccaaatc ctctaatagt caccaagtac tttgggtgtt ttggatctcg
     5161 ctcgattttt tctcgcaaat gactaacgtg tacatctacg attcggcttt gtcctgcgaa
     5221 gtcaaaattc caaatgcggt ctagcaatgt gtctcggtcg atcacacggt cttttcgttt
     5281 catgaaataa acaagtaatt caaattcttt cggtgttagt tcaatcagat ggtcgtctac
     5341 ggtcacttga taattggtca aatcagcagt gatttgtcca atcgatagat attcaggctc
     5401 agcttcatct tttgattgct tacgaggttc aattcgtctg aatattgctt tcatacgggc
     5461 taatacttcg cgaggactaa atggtttggt caaatagtcg tcagcaccta tttctaggcc
     5521 aatgatccga tccacttggt catctttagc cgtcagcatc aaaatcggtg tttcattttt
     5581 ttcttgacgc agccgctgag tgatctccat gccatccatc gttggaagca tcacatctaa
     5641 aatgatgaaa tcaaatgatt gttctaatgc taattctaat ccttcgcctc catctgtggc
     5701 actggttacc ttgtagcctt ctttttccaa attgaacgtc aagagcgtta caatagaagg
     5761 ttcatcatca acaactagta tttttttcat tcaaatctcc tttaaatagg tttcattctg
     5821 tttatatttt agcatagaat cagtacaaag ggctatttta caaaagaaat aaatggtata
     5881 ataggaaggc actttgctga atagaaagga agagcagtca atgattggaa tcagtgcatg
     5941 tttaggcggt ctggcctgtc gctatgatgg acagaaaaaa gaagtaccag aattgatgga
     6001 actagttgaa actggagaag ctgtcatggt ctgtccagaa gtgatcggcg gattaccaat
     6061 tcctagagat cccgctgaaa tcattggtgg aaatggattc gatgtgtgga aagatcaagc
     6121 aaaagtatgg acgacaagcg gcgaagatgt aacggaagcg tacaaaaatg gcgcgatcaa
     6181 agcctatcaa aaattgcagg aaaaacacat tgatctagtc atcatgaagg aaaaaagccc
     6241 ttcatgcgga acccattcga tttatgacgg aagtttttcc ggaataaaaa aaaatggtgc
     6301 cggagtggct actgcttatt ttattcagca aaaaatgact gtgctctctg atgaagaatg
     6361 gctgaaaact agaggtgagc agaatggaaa tcgaaaagac caatcgaatg aacgcgctct
     6421 ttgaatttta ttcgacctta ttgacagaaa aacaaatgaa ctacatggaa ttatattatg
     6481 cagatgattt ttcattaggt gagatcgcgg aagaatacga agtaagccga caagcagtat
     6541 atgacaatat caagcggaca agcaagatct tggaggatta tgaaaaaaaa ctccatcttt
     6601 tttctaatta tattgttcga gaacaggtat tggaaaatat gactgcatat attacagata
     6661 agtacccgga agataaaaaa ctacttgaat atgtacagca aattcaagca atcgaagaat
     6721 aaataaaagg aatgaagaaa atatggcatt tgaaagctta actgaacgtc tccagcaggc
     6781 gatgggaaaa ataagaaaaa aaggaaaagt atcagaagct gacgtaaaag aaatgatgcg
     6841 ggaaatccgc cttgccttac tagaagccga tgttaacttg caagtagtca aagattttac
     6901 taagcgcgta cgcgaacgtg cggtaggggc agaagtgctg gaaagtttat cacctgcaca
     6961 acaaatcgta aaaatcgttg atgaagaatt gacgatcaca cttggttctg aaacagcaga
     7021 gttaaataaa tcaccaaaaa taccaactgt tatcatgatg gctggtcttc aaggggcagg
     7081 taaaacgacc tttactggta aattagccaa ttatttaaag aaaaatgaaa atgctcgtcc
     7141 gctcctaatc gcaggggacg tatatcgacc agctgcgatc gaccaattga aagtattagg
     7201 tcaacagcta gacgttcctg tatttgatat gggaactgaa gtcagcccgg tagagatcgt
     7261 ccgtcaaggg atggagttag caaaagaaaa gaaaaacgac tatgtattga tcgatacggc
     7321 aggacgtctg catatcgatg aaacattgat ggatgagttg aaacaaatca aagaattgac
     7381 gcaaccaaat gagattttgc ttgttgtcga tgccatgact ggtcaagatg ccgtcaacgt
     7441 agctgatagc ttcaaccagc aattaggtat tacaggggtc gtcatcacta aacttgatgg
     7501 ggatactcga ggcggggcag cactatcgat ccgctcagtg acaggcgcac caatcaaatt
     7561 catcggttct ggtgaaaaat tgactgactt agaagtattc cacccagatc gtatggctag
     7621 ccgtatcctt ggtatggggg atatgctgac attgattgaa aaagcgcagc aagactacga
     7681 cgagaaaaaa gcggaagaac ttgcacagaa aatgcgggaa aattcattcg atttcaatga
     7741 ctttattgaa cagcttgatc aagtgatggg tatgggccca ctggaagatc taatcaaaat
     7801 gatcccagga atgaatcaag tccctggaat cgaaaacgtc aaggtagatc caaaagatgt
     7861 tgaacgcaaa aaagcgatgg tttattctat gacgccagca gaaagagcaa atcctgatct
     7921 gttgaaccca agccgtcgtc gccgaattgc tgccggttct ggaaacagtg ttgttgaagt
     7981 gaatcgaatg atcaaacaat tcaaggaatc aagaaaaatg atgcagcaaa tgtccaaagg
     8041 ggatatgaac atcccaggta tggaccaaat gtttggttca ggcgtcaaag gaaaactagg
     8101 caaaatggcg atgaatcgaa tgatcaagaa aaataagaag aaaaagaaaa aacggaaata
     8161 agatgaaaaa aacagcttcg gtacagactg aaaatgtcta ctgccggagc ttttctatca
     8221 gcaattttta ttctttacta atacaattac tctaaacgaa gaggtggcac agatgagatg
     8281 tccgtggagt gaacaaacag aaagtatgcg gcaatatcat gatactgtct ggggtgttcc
     8341 tgaatatgat gaccaaaagc tgttccgaaa attgatgctt gatattaatc aagccggatt
     8401 gagctggcag acgattttaa ataaaagtga agcattcgat gaagcatatg atcgattcga
     8461 tatcaaaaaa gtcgcaaatt atggagaaac aaaaatcagt gaactaatgg aaaacaaagg
     8521 aattattcgt aaccgaagaa aaatcgaagc agccgtccaa aacgccaaag cagtcttgaa
     8581 aattcaagaa gaaatcggca gtttttcaga gtatctttgg tcgttttcta atggaaaaat
     8641 cgttgattct tcttatcatt cacaagaaga agtcccaaca acaagtcctc tttcagatga
     8701 attagcaaaa gatctaaaga aaagaggatt taaatttatc ggaagcacaa caatctatgc
     8761 ttttttagaa gctgtcggga tcatcaatga tcaccttgac agttgtttcc gcaaagaaga
     8821 ggtcgtacgt atcggcagaa agggcgaata aagcatgcga aaaatcatat tttatggtgc
     8881 tataagttta gatggctatt tggcaacgaa aacggatgat cttcaatggc tttttgacac
     8941 tccaacaggt aagcaaacta cttatgaagc tttttatgaa acaatcgata cgaccatcat
     9001 gggcagaaaa acttatcagg aagcaaaaaa atatttggag accgaagcaa tttatccaga
     9061 gaaaaagaat ttcgtttttt ccacccacgc acaattacaa ttgccagatg ctgaggtcgt
     9121 aaacgaagat cctgttgctt ttctaaaaaa tctacaaatg acagaaggaa aagatatctg
     9181 ggttgtgggt ggcggtcgat tgatcaaacc gctattggaa catcaaatga ttgatgaatg
     9241 gtatatccag attacccctg tattattagg ggacgggatt cctttattcc aaaaaggaac
     9301 atatgaagcg cgttttgaaa tgctagacac gacacgattc ggtgaattta tcgaattgca
     9361 ttatgtacga aagtagaagt aaataaaata aaaaaggcaa ctatatgcag aaatgtcctg
     9421 tacatagttg ccttttttat taccgttatg ctttttactc tgttaatttg ttagaaaaat
     9481 ctagatacgc atctaaaatc gtttggaaga aacttaatgt tccttcaacg atattaccat
     9541 tttcatcaat tagattcgca acgtttccga tatatgcttc cggttgctgc aaggttggca
     9601 cattcaaaaa gacaagtgat tggcgtagat ggtggtttgc gccaaagccg ccgatcccac
     9661 ctggtgatgc agtaacgact aaacctggtt tatgatccca aacactgtgt ccataaggtc
     9721 ttgagcctac atctaaagca tttttcaata ctgctggcac agaacggttg tattcaggag
     9781 taacgaaaac gacaccgtct agtcccctca cttcctcacg aaaacgagtc cattcagcag
     9841 gagcctgttc tggagtttcg agatcctcat tgtaaaatgg cagatcatcg atttttacaa
     9901 atacactttc gtacccttca ggaagcaatt tcgcaaaagc ttctgctact tttttgttgt
     9961 aagaatcttt tcttaaacta ccaataaaaa atccaatttt ttttgtcata cgatttttcc
    10021 tccttcaaac tatctataat aatcttacaa aagataagta actggagcaa ataaaaacac
    10081 ttactgacaa aagctacata gaagatagat tacttatttt taacaaaaaa gaagtctaaa
    10141 atcttctatt ttctaaaaaa aatcgaattt aatcaagctg taaagaaaaa aagctttaca
    10201 gggtaaaaaa aaactgttac actacatctt gtgaataaaa caatggaggt ggaaataaat
    10261 aatggcagtt aaaatccgtt taaaacgtat gggttctaaa aagagtccgt tttaccgtat
    10321 cgtcgtagct gattcacgtt ctcctcgtga tggacgtttc atcgaaactg taggtactta
    10381 caatcctttg aaagaccctg cagaagtagt tttaaaagaa gacttagttc ttgactggtt
    10441 atcaaaaggt gcacaacctt ctgacactgt acgtaacatc ctttcaaaag aaggcgttat
    10501 gcaaaaacac cacgaagcta aattctcaaa gaaataaggt gaccggatat gaaagattta
    10561 agcgacttag tcttaacaat cgttcgtccg ctagtcactt atcctgatca agtcaagtta
    10621 gacgtcgtag agtcgaaaga cttttacgag tacaatctaa cagtggctcc tgaagatatt
    10681 ggccgtatca ttggaaaaca agggcgtgtt gctaaagcaa tccgcacaat cgtttacggt
    10741 gttcggatca atgcaccgaa aaaagtgcgt ttgaatatca tcgatgataa ggaaaagtaa
    10801 ataaacgtgc tgtactcgaa ttttcgagtg cagctttttt gtttttttta ttaattgaag
    10861 aaatgattat ttggcaaaac aagcaagaaa gcgtatcctt ataggaggag ggagtgaaca
    10921 gccaatgaga aagaaaatgt tatttattcc atttgctcta ttgttaagcg cttgtagttc
    10981 ggttactcaa gaatcagaca atacacatct atcaagcagt atatctgaaa ctgttaccag
    11041 tccagaaaaa agtagtacca aaacggcttc caccactgaa caaacaatgg ctacctcaaa
    11101 taatgagaaa aagactgctt tagaccagtt gaaagaacaa cagccaaatg ttcccatgcc
    11161 tctagatgta ccagtctctt caggctatct caatatcgca gcgacacata caaagcaagg
    11221 ttattctatt ttatattaca gaacagatcg tcccctcggg ttgaatgctg acgaattgaa
    11281 tcaagaaacg cctattgcaa cctatctata tcaatatggg tttgcttcta gtcaagaaac
    11341 aatccaagtt ttgcagccat ttgagatcga cacaaatggt cagcaagtgg acttaggttc
    11401 tcgaatcaca gggtatcagc aaggtgcagc aggttcaagt tttcttgaat ggcaagaagg
    11461 aaactggcgt attcgaatcc gtgggaataa tatagaaggc caagatccct tactattagc
    11521 taaagaaatc gtagcttatt tggaagaaaa cagtctacca gcacctgaac aatttggtaa
    11581 aattactgtt gatatgggtg atacgacgaa tcgagccgta gaagtaagct ggcaagaacc
    11641 gaaaaatgcc tatacgatca ctcatcaaga tcctatgtct gcgttgaaga tggcagtttc
    11701 tatgaagagg ttgtgaaatc agcgcgctga tctgagccca tcatttaact ccaagtcaca
    11761 ggaagtaatc aaaaatagca cgccgcattt ttgcataatt ttggcttaat accttaaaag
    11821 aaaactagaa ttgcctcttc acacatgcta aaataaaaca gacaaaaaag aaatggggat
    11881 ataagttgac tgaatacttg aatgtaggaa aaatcgtaaa cacacaaggt atcaaaggcg
    11941 aagtccgtgt tatctcaaca acggatttcc cagaagaacg ttacaaaaaa ggaacggtgc
    12001 taacactatt ccaagacgga aaagcacctg tggaattaac agtcaaaagt catcgcaaac
    12061 ataaaaattt tgacttattg agttttgaag gacatccttc tatcaatgat gtggaaaaat
    12121 atcgggatgg catattaaaa gtgtcaaaag acaactctgt agatctagct gaaaatgaat
    12181 tctattacca tgagatcatc ggtctgcatg tattagaaga tggaactgag ttaggtaaag
    12241 taaaagaaat cttgtcacca ggtgccaatg atgtttgggt cgttcaacgt ccgaaaaaag
    12301 ctgatatatt gcttccatat atcgcttctg tcgtcaaaga agtcgattta gaagctggag
    12361 tggtccgtgt agaaattcca gaaggactga ttgacgatga agattgatgt attgacttta
    12421 tttccaagaa tgtttgaagg tcctatgggg gaatccatca tcggtaaggc tgtagataaa
    12481 ggattattag atatcaatat ctctaacttc cgcgattatt cagataacaa acatcagaca
    12541 gtagatgatt atccatacgg cggtggagca ggtatgctgc tcaaagtcca gcccatctat
    12601 gataacatcc aagccattga aaaagctgca ccggatgtca aaaaaagagt aattcttctt
    12661 gacccagctg gtaaacgatt cgatcagaaa atggcagaag aattttcaca agaagaacac
    12721 ttagtattca tttgtggtca ttatgaggga tatgatgaac gtatccgcac attagtgaca
    12781 gatgaagttt ccttaggaga ttatgtcctt actgggggag aattaggtgc gatggtcatg
    12841 atcgatgcaa cagttcggct tttgccagat gtgttaggga atcagacttc agctcaaacg
    12901 gattcttatt caaccggttt attggaacat ccccaatata ctcgcccggc agaatataaa
    12961 gggatgaaag taccagaagt attgacaaat ggaaatcata aattgattga agaatggcaa
    13021 ttaaaagaat cactaagaag gacctatcaa cgtcggcctg atcttttgga aacacttgaa
    13081 tggacacctc aaatgacgaa atttttagaa gaaatcaaga aagaagaaca agaaaaaaca
    13141 gcagatgaag ccaagtgact ttttctaaaa tcttctttac agtaggttga taatatgtta
    13201 gtattttatg gtgagtgcaa aagcacttaa ctattacgat attccgctgt gagaaaagct
    13261 cataagaata tttggaataa ggagaagaaa accatgaatc cattaatcga agaattaaca
    13321 aaagaacaat tacgttctga catcccagcg ttccgccctg gtgacactgt gcgtgttcac
    13381 gcaaaagttg ttgaaggtac tcgtgaacgt atccagttat ttgaaggtgt tgttatcaaa
    13441 cgccgcggtg ctggaatcag cgaaacttat acagtacgta aagtttctaa cggagtgggc
    13501 gttgaacgta cattcccatt gcatacacca cgtgttgcaa aaatcgaagt agttcgctac
    13561 ggtaaagtac gtcgtgcaaa attgtactac ctacgtgcat tacacggaaa agctgctcgt
    13621 atcaaagaaa tcagaagata aacacggaaa acttccttgg aaatctgaaa tttgtgaaaa
    13681 gtccttgtat atcaagggct ttttcttttt tctctatcac agttttaagc catttttggc
    13741 tgttttggac catttttcaa tcatattccc ttaaaaattg tcctagattg tccgacattg
    13801 actatcagtg tcgtcaaaat agggcaaaat ttagtagtca gcttgacgac aaatataata
    13861 cgaaaaatac caaaacattt accgaattta gcaacttttg aacccaagtt tctcaaaggg
    13921 tcagctatta gcaaaaaaga caaaacatgt acttttctac taaaaagttg atgtgatagg
    13981 cttctatcta aataactatt aggagttttt atcgtgaagc aaaatgatgg acgtatcatt
    14041 tggaaaaatc aaagtgagtt aaaactgatt ttaacaatta atgaattcat cgaaaaacac
    14101 ggaattacat ctagccgtca ataccagaaa aagctatcag aaaatccaaa ttctgcacca
    14161 agtatgtggt tcattaacaa aaaatatgga tcatgggaga atttattgat tagtatagga
    14221 cgagaaaata ctgggtatgg aaaatgggct agaatgtcag aacaagaatt attggaaata
    14281 gtagaagcct ttattaagtg cgagaagata acctctcaac gaatgtacga acaaaaatca
    14341 gtagggaaga atattccttc acttagtacc attaaaaaga tgttaggaga tatacgtcca
    14401 ctttttaaag aaaaaaatga tggatctcga tttactgatt tcgaactgct gttagaacta
    14461 aaaaatgaaa taatccgatt aaaactacag gatgatttat caatgacaaa gtttcgaaaa
    14521 ctagttcaat ccccaaaact accatcagtt gatacaatta tgaaaagaac gaacaaaaat
    14581 tgggaggaat tgatggcaga gattggattt gattatcgaa gaatcaaaat ttataagcag
    14641 agaaacaacc tatccaagac aaagaaaact aaatagtatc actctaaatc agacgttcaa
    14701 aattaaaatt tggacgtctt ttttattacc caaaaacgaa aggagattta ttttatgaaa
    14761 aagccaagat ttaagaattg gcgtttgctc gcaacactga gtctattatg ccaaacaatt
    14821 ggtggatcgc ttggcccaac gattgccttt gctgatgaaa ttactcatcc acaaacggta
    14881 actgtggaat tggatttggc tcaccagtat gctgtcgaag gtacatttag cgatggtcgt
    14941 cccatgtcag aagttaccgt tccgcactat gcagtttaca atggtgtgaa gcaagatatt
    15001 ttctgtattg agccaggggt gccgatttac aatgagttca ctcctggtta tgagaaaaat
    15061 ccattgcctg atatgtcgga gaaagcgaaa ttagtttccg ttttatggaa ggaagctggt
    15121 acggatgtgg atacacatat tgtggcccag aagatgattt ggcaagaagt taatggctac
    15181 acgcttcact caattaaacg ttctgatggt agtgcagtaa atatcgcagc cattgagtca
    15241 aaaatcaatc aagccattgc ggattatcaa aagaaaccaa gcttccataa ctccacagtg
    15301 aaaaccgtgt taggtcaatc gactactgtg acagatacga acggcttgaa tttatcggag
    15361 tttgatgaag ttgtcgagaa tatcgcaaat attgattatc gtgtgaacgg caatcaacta
    15421 gtgattactc caaatgccaa ttcaaaagag agtggtgaat taaccctaaa gaagtcagct
    15481 aatacaggaa caccggtagc ttataaaatg gctggtcaac aaactttgat ggcgggggca
    15541 attgataagc ccaataccta cacaatcaaa attgatgtgg aaactgaggg ttctttgaag
    15601 attaaaaaag tcgataaaga aacaggaaat gttgtaccgg gaaccgtttt ccatttagac
    15661 tttggaaaaa cattacctgc aaaagacgtg accaccgata aagaaggcat tgcgacattg
    15721 gatgagattc ctcatggcgc gaaagtaacc attactgaaa aatcagtgcc agctccttat
    15781 acgattgaca ctacaccaat caccgcaacc attaaatctg gtgagactat ttctgtgact
    15841 tcaaaaaata ctcgcgaaaa aggtcaaatc attttgaata aaatgggggt ggaaacagga
    15901 actgatcttt ggaacgacaa atactcatta gccggaaata cgtttgccat tcgcaaagac
    15961 agtccaaccg gtgaaattgt ccaagaaatg accacggatg aaaaaggtca tgcggaaaca
    16021 ccaaaagaga ttgccaatgc gttggaattg ggaacctatt atgtgaccga aaccaaagct
    16081 agtaatggct ttgtgaatac ctttaaacca gtaaaagtcg aattgaacta tgtcaatcaa
    16141 accgtggctc ttgttaccag taacgtaaaa gggcaaaacc aagaaatcac tggtgaaacc
    16201 actttgacaa aagaagacaa agataccggt aatgaaactc aaggtaaagc tgagtttaaa
    16261 ggagctgaat atactctctt tactgcaaaa gatggtcaag cggtcaaatg gagtgaggct
    16321 tttaaaccag agttagtgaa gggaacgaaa gcttctgatg aaacggtgac tttgacttta
    16381 gatgaaaaga atcaagttgc tgttaaacac ttagcgatta atgagtatta ctggcaagaa
    16441 accaaagcac ctgaaggata taccttggat gaaacaaagt accctgtttc catcaaaaag
    16501 gtggatgata acgaaaaaaa tgccgtgatt acccgagatg ttacggcaaa agaacaagtc
    16561 attcgctttg gctttgattt ctttaaattt gctggatcag ctgctgggac tgccgaaact
    16621 ggcttcaatg atctgacctt taaagtatcg ccattggaag gaaccagtga gattacaggt
    16681 gccgaagatg aagcaattac agcttataac gagcaactag gttttgatgg ctatggcaag
    16741 tttgaaaatc ttccttatgg ggattattta cttgaagaag tagaggctcc agaaggattt
    16801 caaaaaatta cgccattaga aatccgttct acttttaaag aaaataaagc ggattacact
    16861 aagagtgaat acatttttac gattaccgaa aaaggacaaa aacaaccaat taaaacggtg
    16921 accgttcctt acgagaaact gacgaataaa gcattttctg ttagcttgaa tcgtttgatg
    16981 ctctatgatt tacctgaaga agaagatagc ttaacttctc ttgggacttg gaaagacgga
    17041 ggcaaagaat tgacagacct tgattctacc gagctagttg ataaattgag ctataacttg
    17101 catgaaatca aagaagactg gtatgtggta gcgcaagcca ttgatgtgga agcgacaaaa
    17161 gctgcccaag aaaaagatga aaaagccaaa ccagtggtaa ttgccgaaac aaccgcaacg
    17221 ttggcgaata aagagaaaac aggaacttgg aaaattttgc ataaattaac cgcagaacaa
    17281 gttttggata aaaccatcgt cttattcaac tatgtgtatg aaaacaagaa accctatgaa
    17341 gcaggtgatg atccagtagc gaaagatgct agcttgaaca atcaagccca aactgtcaat
    17401 tgtacggtgg aacgccatgt ttccatccaa acaaaagccc acctagaaga tggttcgcaa
    17461 acctttactc atggggatgt ggtggatatg ttcgatgatg tgtcgattac ccatgatgta
    17521 ctggatggct caaaagaagc ttttgaaaca attctgtatg cattacttcc ggataatacg
    17581 accaaagaaa tttggaaatc tggcaaaatt gattatgaag tgaatgacaa agaattcact
    17641 aaaaccgtac ttgcggaaaa agtggacaca agtaaatatc cagaaggtac aagttttacc
    17701 ttcaaagaaa ttaactatgg caaagacgga aacatcaatg ggaaacacaa tgaggatcta
    17761 aaagaaaaaa ctcaaacttt aacacctaaa aaagttccga caacaccaag tgcaccagaa
    17821 caaccggaaa taccaactgt tccaagtgac tctcaagaat ctagtcctac agtaaagaca
    17881 ttcccacaaa caggggagaa aaattctaat gttctgctgt ttattgggtt taccttgatc
    17941 tttgcgactg ctgggtatta tttctggaat cgccgaaact aaggtgatgt gatgaaacaa
    18001 ctaaatagga aaaaccaacg tgcgcgaccg cctcctaaaa aaagtggtcg cgctattttt
    18061 gtatccaaaa ctaaaaatga aaagaggaaa agaagatgga attgaaattt gttgtgccag
    18121 atatggccga aacctttgga aagataaggt atgccggcga aggcgaagtt ttaactgaag
    18181 gatatgggcg gaatactaca gtaattggtc gtagttatca tttgtattcc agtaagcaac
    18241 gagccgatga tattgaagtg gtggtagctg cggaagccgg cgaaaaggat tttgatcaag
    18301 atcaaccact aaaagccgtg aatccccatt tggttgccaa aggctatgag attgagaatc
    18361 gtgggtttac cgactacgtg ttgtatgtcg atgatttagt gaaagcatag gaggaaaaga
    18421 agatgagatt aacagaaggt attgttgtag attcaggact aacgtttggg aaattacgat
    18481 tttccgcatt acgccgagaa gtacggaagc aaaatgagga tggaacggtt agtaacgagg
    18541 taaaagaacg gacttataat ttgaaatcct ctgcgcaagg tcgaatgatc caagttagta
    18601 tcccagcaaa tgtaccctta cgcgagtttg cctatgacgc agaggtagag ttggtcaatc
    18661 caatcatgga tacggtcgcc aattatgttt tccgagaagg aactactgtc aattggttca
    18721 ttaaggccga tgatttagtc ttgaaacgac aaccagatca gggaaattct acaaaccaaa
    18781 atgaaggaaa gaaataggtg aagcgtatgg aaattaatgt tgaacatatt ttagattgtc
    18841 tcgatcaata tggaaaaggt gagctaacgg aggaacaact cactaaagca ttaacctatg
    18901 atgaaaaaat gtttctgatt atgcatcaag ggttactgga agtaggtaac gatgtcgaag
    18961 aagattttga tgtactgaat tggttagggg aagaagagtc cttctttatg gttatcgaag
    19021 taaatgaaag tctatgtcga gaagccgaaa ccgtattgga agaaattggt gtggaaatgc
    19081 cggatgccat tgaagttttt ttaaagcaac tagtggaaac gaaacaactc cctatagcag
    19141 taaatgacta gcataactgc ttgaaattgg atcaatgaaa tcctatgaag cttttttcga
    19201 ttggaggtgg aaaccataaa aatgtacaaa gggcatcgta tacgggcagg agatcagcac
    19261 ttggtttatc actttgttct tggctggcta ctcgctctgt tcatcggttg gatgagcgtc
    19321 ttttattttc aagagcttag acaatttgat atttctaagc tatcactttc tactatagaa
    19381 atcgttcgtt ctataaaaga tttaatctat ttgctaggaa gtctcgttct ttcaggaagc
    19441 acgatgttgc tttatataca cttttttcag gatcattggc gcagtttgtg gcatcgacaa
    19501 aagctagccc ggatgattct agaaaatcat tggtacgaag taaaacaaac tcagagtgaa
    19561 ggatttttca aagacctcaa tagtagtcga accaaagaga caatcagtta cttccccaaa
    19621 atctattacc gtatgaagga tggtttactt tctattcgcg ttcaaatttc actgggaaaa
    19681 tatcaagatc agcttttaaa gctggaaaag aagttagaaa gtggtctata ttgtgaacta
    19741 gtagaaaagg aactcaaaga ctcctatgtg gagtacactt tactgtatga tataattgcc
    19801 aatcgaattg ggatagacga agtagtggca gaaagtgggg ctttgcgatt gatgaaaaat
    19861 caagtatggg cttatgattc tttacctcat atgttaatcg ctggcggcac aggtggtggg
    19921 aagacttact ttttactcac tatcatcgag gctttattaa aatctgatgc cgagcttttt
    19981 gttcttgatc ccaaaaatgc ggacttagcc gatttaggta cggtaatgcc tcatgtctat
    20041 tcccaaaagg aggaaatttc tgcttgtgtg gaagatttct atgagcgcat gatgactcgt
    20101 agcaaggcaa tgaaagaaat gcccaactac aaaacaggag agaattatgc gtttcttgga
    20161 cttccaccaa actttttaat ctttgatgaa tacgtggttt atatggaaat gttaacgacg
    20221 aaggaaagtg cggtgatttt gaataagctc aaacaaatcg tgatgttagg tcgtcaatct
    20281 ggtttctttc tgattctagc ttgtcaaaga ccggatgcga aatatttagg agacgggatt
    20341 cgcgatcaat ttaatttccg ggtggctttg ggtcgtatga gtgaactggg atattccatg
    20401 atgtttggcg aggttgataa aaaattcttt atgaagcgta tcaaaggtcg aggctatgta
    20461 gatacgggag ggagtgtgat tagtgagttt tatacgccac ttgtaccaaa aggatatgat
    20521 ttcttaaggg aaattagcga cattggtgga ttaaacgtta atacggaagg ataaaataat
    20581 agtatgtagc ctaggagtgt caagaatcct gggctttttt tacgaggtga tttatgacat
    20641 ttttagattt attcgctggg attggtggct tttgcttagg tatggaacaa gcgggtcacc
    20701 agtgtatcgg cttttgtgaa attgatgatt ttgctcgcca gagttataag gcaatccatg
    20761 atacaagtaa ggaggtggaa atgcatgaca tcacaagtgt atcagacgag tttattcaat
    20821 ctctcggacc agtggatatc ctttgcggtg gatttccgtg ccaagctttt tcaattgcgg
    20881 gaaagcggca aggattttcc gatactcgag gtactttatt ctttgaaatc gctcggttcg
    20941 ccgctattct ccaacctaag tttttattcc ttgagaacgt ccggggatta ctcaatcacg
    21001 aaggaggggc tacgttcgag acgatcctcc gaacgctgga tggattgggg tatgatgtgg
    21061 aatggcaagt gcttaactca aaggcctacg ttccccaaaa ccgtgagcgg atcttcctta
    21121 tcggacattc tcgagacgca tgtaccgaac aagtatttcc tatcattgga tcgtctccaa
    21181 catctgatca aaacatcaga aacttattaa atatcaaccc ttccaatcga ggaatggggg
    21241 gacaagtcta tgggtcagat gacgtagcgc ctaccttgac cggtgatgaa ggaatcaaaa
    21301 tcgcattgcc ggtaga
//
LOCUS       DADQDV010000054        20185 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.055, whole genome shotgun sequence.
ACCESSION   DADQDV010000054 DADQDV010000000
VERSION     DADQDV010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 20185)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20185)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20185
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.055"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            212..1018
                     /gene="proB"
                     /locus_tag="J8S10_002046"
     CDS             212..1018
                     /gene="proB"
                     /locus_tag="J8S10_002046"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HAZ9630626.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            1015..2262
                     /locus_tag="J8S10_002047"
     CDS             1015..2262
                     /locus_tag="J8S10_002047"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HAZ9630627.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVTGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            2338..2682
                     /locus_tag="J8S10_002048"
     CDS             2338..2682
                     /locus_tag="J8S10_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630628.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(2799..3125)
                     /locus_tag="J8S10_002049"
     CDS             complement(2799..3125)
                     /locus_tag="J8S10_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630629.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(3498..4700)
                     /locus_tag="J8S10_002050"
     CDS             complement(3498..4700)
                     /locus_tag="J8S10_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAZ9630630.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            4817..5332
                     /locus_tag="J8S10_002051"
     CDS             4817..5332
                     /locus_tag="J8S10_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAZ9630631.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(5531..5977)
                     /locus_tag="J8S10_002052"
     CDS             complement(5531..5977)
                     /locus_tag="J8S10_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HAZ9630632.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(6024..7502)
                     /gene="msr"
                     /locus_tag="J8S10_002053"
     CDS             complement(6024..7502)
                     /gene="msr"
                     /locus_tag="J8S10_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Msr family ABC-F type ribosomal protection
                     protein"
                     /protein_id="HAZ9630633.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(7856..8485)
                     /locus_tag="J8S10_002054"
     CDS             complement(7856..8485)
                     /locus_tag="J8S10_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAZ9630634.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVTRDHGYETNPI
                     GGVEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            complement(8469..8933)
                     /locus_tag="J8S10_002055"
     CDS             complement(8469..8933)
                     /locus_tag="J8S10_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAZ9630635.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(9420..10688)
                     /locus_tag="J8S10_002056"
     CDS             complement(9420..10688)
                     /locus_tag="J8S10_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosaminidase"
                     /protein_id="HAZ9630636.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(10919..11656)
                     /locus_tag="J8S10_002057"
     CDS             complement(10919..11656)
                     /locus_tag="J8S10_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAZ9630637.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(11723..12292)
                     /locus_tag="J8S10_002058"
     CDS             complement(11723..12292)
                     /locus_tag="J8S10_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HAZ9630638.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLLVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            12420..13292
                     /locus_tag="J8S10_002059"
     CDS             12420..13292
                     /locus_tag="J8S10_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAZ9630639.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            13634..14506
                     /locus_tag="J8S10_002060"
     CDS             13634..14506
                     /locus_tag="J8S10_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAZ9630640.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            14503..16461
                     /locus_tag="J8S10_002061"
     CDS             14503..16461
                     /locus_tag="J8S10_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAZ9630641.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(16712..17563)
                     /locus_tag="J8S10_002062"
     CDS             complement(16712..17563)
                     /locus_tag="J8S10_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAZ9630642.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            17686..18153
                     /locus_tag="J8S10_002063"
     CDS             17686..18153
                     /locus_tag="J8S10_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HAZ9630643.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(18416..18898)
                     /locus_tag="J8S10_002064"
     CDS             complement(18416..18898)
                     /locus_tag="J8S10_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAZ9630644.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(18998..19861)
                     /locus_tag="J8S10_002065"
     CDS             complement(18998..19861)
                     /locus_tag="J8S10_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAZ9630645.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
BASE COUNT         6070 a         4156 c         3662 g         6297 t
ORIGIN      
        1 aaactactcc tattctaaca tatccgaggc tgtaaaagac tttctttaca aattcttcaa
       61 gaaattctgc tatcttaaag taaaccatta attcgttctt tttccaaacg actacaagtt
      121 gtacaaaaaa actatttttt acatgacttt actcgtcaaa acaagtagaa tagaacgaaa
      181 ttaatgagtg gatatttgat tgaggtgtca catgcgtaaa gaaattaaaa atgcaaaacg
      241 aattattgtc aaagtaggaa caagtacatt gatttatccc aatggaaata tcaatcttgc
      301 ggcaatcgat cagttagctt ttgtcctttc tgatcttaga aatcggggaa aggaagtgat
      361 cttagtctca tcaggagctg taggcgttgg tatgcataaa ttacatttgt cagaacgtcc
      421 gactttgatt cctgaacagc aagctgcggc ggctgttggt caagccgaac tgatgaatat
      481 ctataatcaa agattcagtg tatataatca acagacggca cagatcctcg tgacaagaga
      541 cgtggtagat tatcctgaaa gtcgtaaaaa tgtgaggaat acattggaac agcttttgat
      601 tatggacacg atccctatcg tgaacgaaaa cgatactgta gcagtggatg aattagatca
      661 tctgacaaaa tttggcgata atgatcagct gtcagccatc atggcaaaac ttgtcgcggc
      721 agaccttttg atcgtccttt ctgatatcga cgggttttat tcagataatc cgactacaaa
      781 tcccgaggct cagatgtatc gctatatcga taaaatcgat gaaaagattc tggcacaagc
      841 aggtggtgct ggtagcacat ttggaacagg cggtatgcag agtaaattaa aagccgcttc
      901 taggatattt gaagcaaaca gcgcaatgat tttagcaaat ggaaaaaatc cggcaattat
      961 ttttgatatt cttgcaggaa aagaagtagg tactttattt aaggaggact tgaaatgact
     1021 gacttgatgc aattaggaca acaggcaaaa gatagcgcgc aacaactagc acttatgcct
     1081 acaaaccgca aaaatgagct acttgttcaa atggcacaaa ccatcaaaaa gaatcaacaa
     1141 gcgatcattg aagcaaatca taaagactta gaaaaagcag tcgaaaacaa tatcagtgaa
     1201 acgatgcaag accgcttgca gctgacacct gagcgaatca atgccatggc tacagagatc
     1261 gaaaaaattg cttcgttaga cgatcctatt ggaaaagtag atgagatgtg gacgaacacc
     1321 gacggattga gaatcggcaa aaagcgcgtg ccactaggcg tgaccggcat catttacgaa
     1381 tctcgtccaa atgtcacgac agatgcagct agtctagcat tcaaatcagg gaatgccgtt
     1441 atccttcgcg gtggcaaaga agcattcttc tcgaatcaat tattagtcca attattgcag
     1501 caagtactgg tcagtgctgg cgaatctcct tatgccatcc agtttgtcga tgatacttct
     1561 catgaaactg caggacagtt gatgcgattg acagaatact tagatgtgct gattcctcga
     1621 ggcggagcaa aattaatcca acgagtcaaa gaacaggcaa cggtacctat cattgaaaca
     1681 ggtacaggaa ataatcacgt atatatcgat aaagaagcac agttatctat ggcagtgaac
     1741 atcatcgtca atgcaaaagc ttcccgtcca tctgtctgta acgcggcaga aacattgctg
     1801 atccattctg agatcgcacc ttttttcttg ccagctattg aaaaagaact ggtagaacac
     1861 ggggtctctt tacgtgcgga tgctcgtgcg ttagaatatc tagagacggc tgctttagca
     1921 gaagacacag attgggatac tgaatatcta gattatatcc ttgctgtcaa agtggtcgat
     1981 tctttggatg aagcaattgc acatatcaat cggcataata ctaaacattc agaaacgatc
     2041 gtgacagata gttatgcggc tagtcaacgt ttcttaaatg aagtggacgc ggcggctgtc
     2101 tatgtcaatg cctccactcg ttttacagac ggatcggtat ttggttttgg tgcagagatt
     2161 ggtatctcta ctcaaaagtt gcatgcccgt ggtccaatgg ggttaaatga attaacttcc
     2221 acaaaatata tcatttatgg cgatggacaa atccgcgaat aatgtttcgt gtgaaacatt
     2281 attcccgcct tttgcctttt ttctgtaaag gttctatcca actagaaagg tgtcaatatg
     2341 tttgaaattt taatgatttt ttttatttac cttatttctc tgaatatcgc tgcttttctg
     2401 ggagtcggta ttttatccct tttctttcaa ttcaaaaaac gaagcatagg gagtcaacgg
     2461 gaaaaatggt cgcagtattt tgacaaaatc gggcaaaaag ggctggttac acgcttgcac
     2521 attagttaca tggttgcatt atgcttatta gcgacaatca attactattc ttttttcgat
     2581 cattcaatcg cttatacgat tacgctactg attgctggga tttttcactt atcttataaa
     2641 tatcagctga ataaaaacca cttgaatcgg actttccgct aaaaaatatc cgtacgataa
     2701 gtagagtgcc ttgaagatcg gcaaaaaact gccggacttt ttagaggctg tgacaaagat
     2761 tttgtcacag cctctttttc catataaacg gcgttcgcct accagctgcc tggtaaatct
     2821 gtttcctctt cgttaagaag cgaaaatccg tcaaatgttt cgccatcata ataacgaagc
     2881 agctcatcca tggacaagtt catcgttttt tctttttctt cttccgctga ttcagccagt
     2941 agctgttccc gatacacctg atacatacca gctatttttt gctgcatcgc ttttctagtt
     3001 tcaccttccg cattgattat tggcaattct ttgatatagc cacgataaat caaccgatca
     3061 tctgaaaatt caatgggtaa ttcaacgagt gtcaacccga cttcctgaaa atattcttcc
     3121 agcatctatt atccccccat tctttttctt aaatgaattt tagcttacct actgaaaatt
     3181 ttccagtttc attattttga gaaaaaaagg gaatgtgaca aaaatcgtgt cacatcccct
     3241 ttttccgaat aaatggtgtt cttctgccaa ctcctcaatc ataagtcaca atattcaaca
     3301 aacatgagaa actgtttttt gaaattgttc cttgtgattc agagttaaac gacagtctca
     3361 caacctcttg gtaaacggcg ttcaaaagct tgcatctgcg gtaataagcc caaccaaacg
     3421 aaaaatatga gaagctattt ttgtttggct gttcttatga cttgatgcag gacagctttt
     3481 tcacaacctc tgatttctta ttcttcttca tttgtagcaa aataattacg gtgataaatg
     3541 atacaacata cactgataag aacaatggca cctgcaaaat aaaacgcata gctttcacca
     3601 atatgttcac caatcacacc tgcaataaat ggtgctaaag ctccaccgaa aaagcggaca
     3661 aaactatagc tggacgaagc aacgtttcgt tgcagacctg gtatttccat agcaatcgtc
     3721 gtcaacagtg tattgataat tccttggaaa aatcctgcta acacaatgct gatcggtaca
     3781 aggactggca tagaagttcc agctcctaat aacagcaaac aaataatgaa taagacaaat
     3841 gctgctaaaa ttgtccgata agtcgtaaac ttccgctcaa gagccggtgc aacgaaaatc
     3901 gaagcaatag ccagaagcac accccagcca aaaaatacaa aaccgacttc taattcagaa
     3961 tagccaatca ataaaaatgg cgcatacgca agtaaagtaa agaatccgaa attatataac
     4021 aatgcgatta gtccaactga acgaagttta tgattgctta acgctttgac accttcccaa
     4081 aggcctactt ttctctttgg tttctcagtt tcaggtaaaa gtaccgctag ggctataaaa
     4141 ccgcaaaaca tcaaaaatgc taccccaaaa aatggataac gccatgaacc actgcccaag
     4201 accccaccga ctagagggcc aacagccatt ccgcagccaa gtgctgcttc atacatcatg
     4261 attgcttttt ctgtgttacc aactaaaata ctgacgatcg ttgctaaagc agtagagaca
     4321 aataaagcat tcccgacacc ccagccggca cgtaacccaa tcagcattcc gatattccca
     4381 gataatccgc caagaccagc gaatacaacg atgataaaca atcctgtcat caatgttttt
     4441 ttcaaaccga tccgactaga taagaaacct gtaaatagca tcaccacacc agtgactaac
     4501 atgtaactag taaataacag ggtcgtttca gctggcgtag cgtttaactg tgcagcaatc
     4561 gtttttaaga ttgggtctac tagacccact cccataaaag cgatcataca ggtagctgct
     4621 acaactagcg ctgaactttt cccctttgtt tcttcatttg tttgttcttg tatatctatt
     4681 tgattctcca atatttccat ccctttctct ctattagcat catacatgat ttattttaca
     4741 tgtaaatatg cacatgtaaa acgtggaaac tttactgtga tataataaag aaaataagac
     4801 gagaggtagg atttttatga atactttagc ctatatatta ttatgcgtgc ttttatccaa
     4861 accacgttct gggtatgaat tgaagcagct gatcacaatt ttttgggaag cccatcacag
     4921 tcagatctat acaacgcttg ccaagttaga ccagcagggt tatgtgaccg ttttggacaa
     4981 agacgagcac tctcaaaaaa agatctacca cttgactgat gaaggacgtg ctcttgtaga
     5041 ggaatggatc aaagaggaaa ctcccgctcc tacgcaaaaa gatgaatttc tagcaaaaat
     5101 ctatgctttt tcgacgctcg ataaaacaac agctactgga ctgctattca ctagagaaca
     5161 acagctgaac aaaatcatgc aaaaaaatca aaaaaaattg aatgacctct cgctagacaa
     5221 gaaacaagaa tttggacgtt atgttgtgat ccagcgcaga attatgcttt gtcagcagga
     5281 actccaatgg tgtcagcaag taagagaaca aatgcagcag ttttttgagt aagggataaa
     5341 cagaaccttt ctagaaatat ctattgaaga gcaaattatc ttcaataaaa gagcaataca
     5401 gttggaaaag aaaaagcgat ccgaacgaca ggccaaaacc tatcgttcgg atcactattt
     5461 ttctagaact gcattcaaga gactatgaca aaaagcatgc caaggccttt tttcaaataa
     5521 cagtgttcca tcattcatta ctttgaattg cttttagcac acttcttgaa agcgggccaa
     5581 cgatgatcaa ctgcaacggt aaagcggcaa tcacattcat tttccaagca ttcatataag
     5641 cagagaataa ttgatcaggt attccttgtt ccatgatcac accgaataaa gacatacatg
     5701 tcaccattcc taaaaccatc aagcatgaaa tagttaagat catttggacc ttgctttctg
     5761 gatttactgg tagtttaaag gcaatttttt tcgccagcac accgatgatg aagacatcca
     5821 aaatgaaagc caccacgaat ccaggcacta gaccaatcaa caaacttgat aaatgaagat
     5881 cttgatgcag ccataaatta tacgcgctca tccccaagac catcaaaaaa cacatcattg
     5941 ttgtaaaaat tattccttct tttttatttg taggcaatct gtaccactcc tttaaatttg
     6001 tcacgaaaat catcgtagca catttaaaaa tttctcgtaa gtactttttt tattttctgc
     6061 ccttttattt cataaacttc atcagccgta cgctcgacaa agtaagaatc atgagaagta
     6121 aacaaaatcg ttcccggata tatttgcatt agcttctcta aagcttcgat cgttgccata
     6181 tcaataaaat tagtcggttc atctaacagc aacacattac ttggcttagt aaaaagcaaa
     6241 gcaatcgtca gacgggtcgc ttctccccca cttaatgtac ataacggttt cgtcaaagtt
     6301 tcctgagcaa accctaagtg attcagcaaa ctacggacaa gcgattctga aaactctgtt
     6361 tgtctcatga caaaacgaat gatggattct tcagatgtca tttgataacc cttttgctga
     6421 tatacttgaa agcttacttt cggagagaga aggattcctt ctccttgttt gcggatatgt
     6481 tctaataagg ttgtcttacc tgaaccattt tcaccgacaa tcgcgatttt tttacctaaa
     6541 gaaaactgaa aatcaccatt taccagtaat gttctcccac ttctttccaa ttggacattt
     6601 tgtcccatga tgggatagcg gctgtggagt tcaagagatt ttggtactgg aaaacggatt
     6661 tgtttcatct gctgcggctt ggttgtttct cctatttttt ggagtcttct ctctaatgtt
     6721 ttcgcattct tttggatggc tttttgtaca ctgtcttttt gtttagagga agacaaccga
     6781 tccggtctga tttgttgctt tttcttttta ctggacactt tttccaactt ttccgcttgt
     6841 tttttctttt cttggatcga tttttccaat cgttttttct ctttcatgat cgactctgct
     6901 tctcgtagct gagtcttttt ctccaattcc ttttgagtga gataggcact ataattcccc
     6961 gaaaactctc ggatttctcc gtcttttact tcccagattt tcgatgctag ctcatctaga
     7021 aaatagcgat catgactaac aaaaaccagc gtaccataat aataacgaag ctcttcaatc
     7081 agtcgatcaa tactttttct atctagatgg gttgttggct cgtctagaag catcccttgt
     7141 tcataagaag aaagaagacg tatcaactcg atctttcgtt cttcccctcc gctccatttc
     7201 cgctctgaag tttcttccag tcttaactgg aaatgactgg ctaattccaa atttaggtcc
     7261 tttgcttcag cgagataggt taattgaggc aggtagttga aggtgatctc tgtttggatt
     7321 ttcccatgat cgggaaaaag ttcaccggct attagtttga gcaaagtcga tttaccgaca
     7381 ccattttctc ctatgatccc tatacgatct tgctgataga cacgaagaga atcaatagat
     7441 agttctagct ggttgccaaa gctgacttgt agatttgtta tatttactgc taaattttcc
     7501 atatgtttta cactcctatt tcatgtaaaa caacaattat cgatactaaa aaagagcaga
     7561 aaaatctgtt tgcaaaaaaa ctgcatcaca tcttttccta ctctgaacga aataactatg
     7621 actaaatcac caaatctgtc atagctttca cctattctac tgtcgttcga aaaaatggac
     7681 atactccatc catgaaattg ttgtttatac atgtcttttg aatttattta gttgttattc
     7741 aaaagttcga aacgtaattt catcgatgca gtcatttttc cgacctcctt ttttattagg
     7801 ttaccacaca cgattcaaaa aaagcaatag ctactgaata gtaactgaaa accttttatt
     7861 cgaacgtagt gatcttttct ggtgctaaac gaacagactc gtaaccttct tctaccgctt
     7921 ttcctattga taaaataata actggaacat aacggtcttt atccaaacca aatgcctctg
     7981 ccaactgatc tgcttcgact ccaccaattg gatttgtttc atagccatga tcacgcgtaa
     8041 ctaacatgaa ttgcatagcc gctaagctag aatcgacttt gactacatcg ttcatttctt
     8101 ctcttgaaaa actcttgtaa taaggaatga tcgcagctaa ttgttgatct ctgacttctt
     8161 ttggcatctt ccctgattcg taagcttggt tatagatttc ttcgccatat tcgtaacatt
     8221 gcatatcgcc aaaaatcatg accattgcag aagaagtatc attttgtctc gtattgaaac
     8281 ggatcaaagg acgcaagatt tcttttgctt cctcgctttc agcgaccaca aagcgccatg
     8341 gttgcatatt gacagaagaa ggtgcagtcg tcgcttcttt gatcatttcc agcatttctt
     8401 cgtgtgggat tttgtatgtt tcatcatata cgcgaacgga tcttctacca gtcataattg
     8461 ttgaaaaatc atttttttgt tccattatta ttaacctctt tcgtttctgt tgttatattg
     8521 caaagttggg tattcaattt atctaaaagt gttagaaatt gtttcatttc tacatcgctg
     8581 aaagccgggg atagcacgga acctgtatct ttatggtcca tttcacaatg ctcgattttc
     8641 ttctgggctt tttctgttag cgctacatac acttcccggt tgttctgagg atttctctga
     8701 cgcgaaacat agccatttgc ttccaatacc ttcagatgac gagtaactgc tccttgatca
     8761 atctgcaact tttcttgcaa actgctttgt agcaatggat tttcttcttt cagtctcatc
     8821 atgatctcgt atctagtaag acttataccg atattttctt caaagatctg gacgattttt
     8881 tgatcggcta atttgatttg atataaaagg tgactaatct cttctaaaga cataatttcc
     8941 tcctttctaa taattgactc gtcaacgatt gacttgtcaa taatagaata aaaaaagaaa
     9001 aaagtcaaag aatcagctgt gtaataaaaa aaacgctctc aatagaaaag tatagagaaa
     9061 agaaattttt tgtagaatga acggaaaaaa tgataaagaa agcacaacgc taaaaccaag
     9121 attattgatt cttatcaaac tatagaagat agctcttctg cagtagaaaa ttttacaccg
     9181 ccaaaaattt ccgaaatcgc cttttgcaag aatcccgtcg aatattagaa attggatcag
     9241 tatgcttaaa cagtaataaa aaagttatga caagatgttg tcacaacctt ttttgagtaa
     9301 acggtgttca aaaacttgca tctgcggtaa taagttcaac caaacaaaaa acatgaaaat
     9361 ctgtttttgt ttggctgttc ttactacttg atgcagggca gctttttcac tacctctttt
     9421 taataaccat aaaatcctat tccttcatat ctccagccca tcggtgttag ccaatctctt
     9481 tccttagcac tcaaggtata gtgatgggta ccagtttttt catttggatt aaatagtcga
     9541 taaattggct tggaaccacc agaataaaaa cttagacctt cataacgcca accgattttt
     9601 gttaaagagt tgatctcaga ttgtgccatt gtgtaatgat ggtctccact gtaaggattg
     9661 tataaacggt agacaggttg tccgctgttt ggtgcttgcc aagcaatccc ttcatattcc
     9721 cagcctacag ttggcagata atttttttct ccggcattca atgtatataa atgttctcct
     9781 gtatgacggt tatacagacg atacatcgga gaagttgaag ttggtgctgt atcatactgt
     9841 gtcagattat aggtttcgat tacattgttc aatgtagaac cataattagg cgcagtggca
     9901 taacgacctg ttagccaagc cgtagcatct ttgtaagagt tcgtattgct tttccatgca
     9961 ccggaatagt agtaaacgcc tggctgaaaa gaagtcgtct tcaataccgt tacgttatct
    10021 tgcaatgatt ctttgtacga aggatatttt ctaaaagcgg cattcaccgt aatccattgc
    10081 ccattcacat attccgaagt aggcatcgta acagattggc cattatagct tcctttaatc
    10141 ccaaatagat tgtaattagg ggcagaagcc aaagtactgt tcccccagcc actttcaacg
    10201 atggcttgag caatcatgac tgatgcatat aagtcattgg cacttgccaa actttgtgca
    10261 gttgaggcaa tactatcaat gaacgcttgt tgagaattag cagatgagcg agcataaaaa
    10321 gcatagccag tatagttttc gaattcagac aaatctgctt gatgggtatg tgtcaatgtt
    10381 tgcccatctg tcaattggtt cgtgatttct tctgcattct ctggattgtt ctgagcttct
    10441 gctgatgtac tgtcttcggt ttgtgtttgt tctgttgttt cagttgttgg ttcttcggtt
    10501 gaaattgtat tttctgagac agtagctgac tgcaaagtac tctctgtatc gttttcaatt
    10561 cctgtttctg aagaactcga tgtctgagtt gcgacagttt ctgtcgattc ttcagctagc
    10621 actgttgtgt tggcaactgc tagatttcct aaaagaataa cgctaaataa taaattcttt
    10681 gctttcatct tttttctcct ttgaattatg aaacttttcc taaataacag tgtaactaaa
    10741 aaagtaaaag caagtcaatg tccatattta aataacattt gtttcttttt gataaatttg
    10801 ctttttctac ataaaaagac gtaaatgaag aatattcttc tccattcacg ccttaaattg
    10861 atggtcgttt gaataactat ttaacaagta attctctttg gatattatcc gttatggatt
    10921 atacttcctg tgtcgtcgga cggataatca tgttactgac agacatccgg tctggcgttt
    10981 ctatcgcaaa tgctacagca gaagctatat cttcggaggt caatccccat tctttttgcg
    11041 cttcatgaag ttcaagagca gcctttttgt cgctgatggt ttgatataat tcagtttgaa
    11101 cagctcctgg agagatgatc gtagatttga tgttattttg ccgttgctct tgacgtaatc
    11161 cttccatgat tgcacggaca gcaaattttg ttccgcaata aacggcggaa tcaggataaa
    11221 caacatgtcc cgccacagaa tcagttgaaa tgatatgccc agatttttgt ttttccatga
    11281 ttggaagtac ggcggaaatt ccatttaaca cacccatgat gttgatatca agcatatttt
    11341 gccattcatc acggtgacct tcaactaatg gagcggttgg catgattcct gcattattgt
    11401 acaatacatc gattcgaccg aacttttcca tcgctaaatc gataactgct tggacttgtg
    11461 caaaatctct tacatctgct gtttgaatat atagctcagc ttctggtaaa gattctttta
    11521 ttgcttttag gcgatcttct cggcgtgcag ctataactag tttagcccct ttttctgcta
    11581 atagcttcgt tgttgcttca ccgattccgc ttgaagcgcc catgatgaca atcacttttt
    11641 ctgataaatc attcattcta ttctcctcct gttttgaaaa atctcttgct tatactcact
    11701 atctcttatt tcatcttact gttcaaataa tccgttcgac aggtttgacg attttggcag
    11761 ggattcctgc aacgatggta ttgtctggga catctttcgt aacagttgca ttcgctgcaa
    11821 caatggcatt ctcgccaatc gttacgcctg gcagaatagt tgctcctgct ccgatccaag
    11881 catttttctt gatgtggatt ggctttacta acaagcctct tcgttctttt ggatcggtta
    11941 gatggttcac cgtgatgagg ttgacacgag gaccaatcaa tactgaatct tctaaacaga
    12001 tgccacctaa gtcaacgaac atcacttgac gattgataaa gacatttttc cctatactaa
    12061 tatgtttgcc gaaatctgta taaaaaggca gcagaacagt caccgtatca tctactttgt
    12121 cactaatgat attttctagc cgtttgcgga tatctgctgg ttcatggtac ccagtattca
    12181 gcgctgctaa aggctcttcg ttttcagctt ggatctgatg gatcacttca aagagcggat
    12241 ccgttactcg aatctcttta ttgacgattt gtttttcgat gaggcttgtc attttgctcc
    12301 ctccttttat ccttacttta taacggacgg cttatcatgt ctaatactta taaaacatac
    12361 ttaactattc cttttaacta tacttagtgg tatgcttttt taaaaacagg agggaaaaaa
    12421 tggatattcg tatactgacg tattttttag cagtagctag agaaaaaaat atcagccgag
    12481 cagcaaaatc tctgcatatc acgcaaccta ctctctcaaa acaactgaaa gatttagaag
    12541 aagaacttgg tgtgacactt ttcactcggg gctcccgaga gatacagttg acggattctg
    12601 gtcgatatct ttattcaaaa ggaaaagaaa tcttgtcgtt ggtagaaaaa acggcgaaca
    12661 atttaacaaa tgacgcaatc atctctggag aaatctacat tggcggaggc gaaactaaag
    12721 caatctcttt catttctgat agccttcatt cgttgatcaa ggcgcatcct gatatccagt
    12781 ttcatttata tagcgggaat gcagatgata tcatagacaa actggatagc ggattacttg
    12841 attttggact cgtaatcgaa ccgacaaaca aacaaaaata ccagtcattt cgactgccag
    12901 cccaagatcg ttggggactt ttgatacatc gaaatcatcc tttagcaaag caaaccgtca
    12961 tccatccgca ggaactgaaa actgttcctt tgatcatttc ccggcaaacg tcagtggaca
    13021 gtcaactagc tgaatggcta ggtttcagca tagatcagtt atcgatcgtc ggaacatata
    13081 acttattgta caatgcttct ttgatggtcg ataacgggac ttttggtgca ttagctctag
    13141 atgggatcat caatacttat gggacggaaa aaatattcat cccactcgat ccgccattac
    13201 aagcttcact gaatctcatt tggaaaaaag accagcctct ttctcctgct gctcgtaaat
    13261 ttttagatgt cctaacggag aaatacagtt aagtagagtt tttttccttc gctttcagct
    13321 ttttaacaac gaataagata agcaaaagat ccaacgatta aataacataa gtttcttaat
    13381 ttatttcttc cttttatttc tgataattcc agtaaattac tataattata aaaaaagaat
    13441 tgacaaaaca taactgtcta tataaaattg attacgttaa caataattcg tttcatgtga
    13501 ctagatcata ctaggcatga aaaatctctg aggaacatgg tttccctagg aggtttttcg
    13561 tgtctatttt tgtttggccg caatcaactg gtctagcaaa cgtgaaaacc aaatcttcaa
    13621 aaagggtgcg cgcatgaaaa tcaaaaagat ctttaatcaa aatgcagtat tggtagatga
    13681 cggtggacag gaaaaagtag ctattggaaa agggattgga tttgacagaa aaagaaatga
    13741 tttgattttt gatcgtgatg tcgaacggat atttgtcatg gaaccagaag gtcaaatcaa
    13801 gttgcaaaat ttacttaatc agattgatga acgcttttta tttgcagcag aaacgatcat
    13861 tgatcatgcg gaaactgttt tgatggaaaa gttgaatgaa catgtattga tcgctttgac
    13921 cgaccacatt gctttttctg cggagaacat taataacggt atcgtcatcc gcaacaaact
    13981 tttaagagaa atcgaagtgc tttacagtga tgaattcagt attgctcaat gggcagtaga
    14041 gtatctgaca aaagagcttg ggattccata tacttatgac gaagcaggat atatcgcaat
    14101 ccatattcac agcggacgaa gcggtcggaa caataaccat cgcagtatcc gtgaagtgac
    14161 gattgtatct gacatcatcc atttagtgga atcagaattg gaaacagata tccattcaga
    14221 accattttca ctgaattatt caagactggt gaatcattta cgactgcttc tacaacgaac
    14281 ccatgcgcaa caatatgctg ttttagacac ggaaatcgta gaaatggtca aacgaaaata
    14341 cccagaaagc tataagattt ctaaaaaaat ccgtgtgttg ctgaccaaag aataccagct
    14401 cgcgatcacg aaagaagaac tgggttactt ggccatccat atcgagcgtt taagaagcgc
    14461 aatcgtacaa acaaatgtta acaatcatga ggaggaaaaa aattgaaagc atatctacaa
    14521 cgaatgggac gttcccttca acttccagtt gcggtcttac ctgctgctgc tttactagta
    14581 gggatcggaa actggtgggc atcttatagt aacgacattg tcgctcattt tttacaagct
    14641 ggcggtaacg cagttttagg tcaattacct ttgctgtttg ccgttgggtt agcactaggg
    14701 atgtcagtgg acaaatcagg tgctgctgcc ttggcaggtt tggtcgcatt tgaagttcca
    14761 gtaaatgttt taaaaactga ttcagtagct actttattga atatcaaacc agaatcagtt
    14821 gatccatctt ttgctcagat cagtaacgta tttattggta ttattgccgg attgattgcg
    14881 gcagctcttt ataatcgttt ccacgaagca aaattaccga tggctttatc tttctttagc
    14941 ggcaagcgtc tagtgccaat cttggctgcc tttgtcatgt tgctgatcag tgcagtgcta
    15001 ctgctcgtat ggcctccggt ttactctgct ttagtttctt ttgctaaatt cattttgagt
    15061 ttaggctggg gtggtgcagg tctttatggc ttcttcaacc gtttactgat ccctacagga
    15121 ttgcatcaag caatgaactc cgtgttctgg tttgacgtag caggaatcaa tgatattggt
    15181 aaatttttgg cttctgaagg aacaaaaggc gtaacaggaa tgtatcaagc tggatttttc
    15241 ccaatcatga tgttcgggct tccagcagga gcatatgcta tttacagaaa tgcacgtcca
    15301 gaaaacaaag caaaaacagc ttccttgatg ctagcagcag cttttgcttc attctttact
    15361 ggtgtgacag aaccacttga attttcattt atgttcgttg cttggccatt atatgtcttg
    15421 catgcaattt tcactgggat ttctttagca gtgagtgcat tcttccattg gacagcagga
    15481 tttgccttta gtgccggatt tgtcgattac ttcctatctt tgaaaaatcc gattgcgaat
    15541 cagccattga tgttgatcgt ccaaggatta gtaacagcag tgatttacta ctttggcttt
    15601 aactttgcta tcaaaaaatt ccatctgatg actcctggcc gcgaggaagc agatctttca
    15661 gatgacgata ctgcaacgac taattcagac aataaatatg cggcacaagc aagcaaaatc
    15721 tacgctgcat taggcggagc cgacaatgta acttcgatcg ataactgtac tacacgcctt
    15781 cgtttgcaag tcaaagatac aggcctgatc gatcaaaata aaatcaaagc cactggcgta
    15841 cctggtatga agatcatcga cggaaaaaat gcgcaagtca tcgtaggtac agaagtacaa
    15901 ttcgttgcag atgagatggc aaaactacat ggtggtgctg cagcacgacc tgcacaaaca
    15961 aacaccgtgg ttaaaacaga aacatttgcc ggtgaaacga tcgaacaaga tatttacgct
    16021 atcgcaaatg ggaaactgat tccaatcact gaagtttcag atgatgtatt cgcggaaaaa
    16081 atgatgggtg acggctatgc tgtattacca gaaaatggag aaatcttctc tccaatcgct
    16141 ggtacgatca caaacatttt cccaacgaaa catgctgtcg gaatccaaac agatgctggt
    16201 atcgaagtct tgcttcatat gggcatcaac actgttgact taaaaggcga accattcact
    16261 ttatatgtag aagaaggtca aaaagtcgca agaggtcaat tgattgcttt agttgatctt
    16321 gccgctattc aatctgcagg caaaaacacg gatatggtcg ttgtattcac aaatggcgac
    16381 aaagtccaaa gcttagaaat cgaacccgca cgtgatgtaa aagcaaatga taaaatcggc
    16441 tctgtttcca acaaagcctg agccatcgtc ttccccagac ttttttatcg ataaacaaac
    16501 aggagctgag acaaaaatct tgtctcagct cctttttccg aataaaaacg gcgttctcct
    16561 gccaactccg cggtaataag tccagctaaa cgaaacatat gaagagctat tttttatttg
    16621 actcttctta ttacttgatg cagaacagct ttttcacaaa atttttcttc atactcaaaa
    16681 ctaatcggct ttttcacaac ctctttatac attattcctg atccaatatt tcttttaatg
    16741 ctgcttcaag agaagttaat ggttttccca atactttttc taaatcatca gaggaaatag
    16801 ctaactgatc ctttttaata tcatgttgga tcgctaaaaa catgtcagct gcttcttgag
    16861 ggaatccggc ttcttttaga ttttcgacaa acgctgcatc acttgcttca ataatttcta
    16921 actctttacc tgtcgcacgc tctaatgcct tggctaattc ttcatagtca gttagattgc
    16981 cggataattc taagatttct ggagagtcac tttctactag tacttttgct gcagcttctg
    17041 catattcacg tttcaatgcc caacctgttt ttccatttcc tgcagcataa acgaattgac
    17101 cagtttttaa agcctgccca atgataggta attcattctc tacataccaa ttattccgta
    17161 aaaatgtatg ggaaatacct gaatccttaa tcattttttc agtgaattgg tgatctggcg
    17221 ctaatacact gatcgagtga tcggcatctg caaaacttgt ataagcgata taagataccc
    17281 cagctgcttg tgctgccttc actacattct tatgttcggc ttgacgattt cctggaacgc
    17341 cagagacaaa aagcaatcga tctattcctt tcaacgcttc tttcattgag tctaaatcat
    17401 cataatcacc aatacgtata ttaaatccag cttctttcag tgcttctcct ttttcttcac
    17461 tacgtactag tacatagatt tcattttgtg gaaccatctt ttttaagaat tccagcgcat
    17521 aaccaccaaa acctccagtt gctcctgtta ctaaataatg catatttgcc actccctatt
    17581 ctttttattt gttaagattt acagctgtac atttataaat tacaccttta tcataaagag
    17641 tgtggtaaga taagtcaagc aaaaaaaatg aaaggatgac aactgatgaa gtattctctg
    17701 caatttagtg atgcaatcca tgtacttgcc tatattgaaa tgtttcaaga tacccgatca
    17761 ctttctagtg agatgattgc cagtagtatc gaaacaaatg cagcaaatgt acgtaaaatc
    17821 atgagtcagc tcaaaaaatc cggtttgatc tttacaaaaa ccggaaaacc gcagccttcc
    17881 cttgccaaaa gtccagatca gatttcttta ctagatgtct atcgcagcat cgaaggtaat
    17941 acacagctta tccaagtcga tccaaaaaca aatccaaatt gcgtcgttgg tgcgaatatc
    18001 caagaagctt tagaagaaag ctacgctcgg ctgcagaaaa aggcagaaga agaaatggct
    18061 aagatcacac ttgatagtct gatacataaa atagccgttt tggaaaaaga aaaaagacca
    18121 gaaaacacag gcctcgtaga gagattttta taattctctc tactgtgcct gcatttttct
    18181 gatcggaatc gtctacataa attcttttat tctccggggg acaaaagcct tgtcatgccc
    18241 ctttttcctc tctaatgctc aggtcaaagc gctgaagtca tgacgtcttg ataaacggtg
    18301 ttcaagtagc tgaccctcgg cattagttct gaaaaatgca aaatatggaa agctatttcc
    18361 catttttcct ctctaatgct caggtcaaag cgctactttc acgacctcta tattatcatg
    18421 gtttattgac taccggtatc cagatttctc ccatatattt cccgttggta actcccattt
    18481 cgactacagc atttggaccc ccaacatagg cgtaatcttc tacttctctt aaaacatgcc
    18541 caaaggccgt attcgtcaaa tcatttctta attcttcagg cgattctgct aaagcgctta
    18601 caacaagata cgttcctttt gggaatggga tgattcgcgt agtgtttgga acatcctgac
    18661 tcgtttgaac accgacatag tacatcattt tcccgttata gggttcgttg actgtaaaga
    18721 aataatgatt ttcagcagct tgtttcaatg catctattgt tccattaccg ataacttttt
    18781 gctcaaatgc ttgtttctct gcagccaaac cgacaaaatc cgtattgcta ctcttcaatt
    18841 ccacaccaat acccgtcacc gtaaaatctg gtttttcttc gatcctatac tttgccattt
    18901 ctcccaccct ttctattata ttaagttcat cttacataaa attaaaggga aatgacacga
    18961 ttacgctctt ttttctaggg atatttttat tttttaacta tttttttgct ttcactgcaa
    19021 tccaaatctc actgtaaaca ttactgaaat cctctcccca ttttgtaaaa gagatctcgg
    19081 gagcttcgac taacccataa tctgaagaag gaagccattc tgcatagatt ttcccccaag
    19141 tatcttgtaa agtttgggga aatggccctt tattaggaaa aatggcccaa gtgtgttctt
    19201 ctatagcaag catttctaaa tcagcgtacg gattttcttt tgtcgtagca aagccaatca
    19261 tgtgcatcaa actgcccttt tcttccaagc ggtctccatc aaatccataa gaaacgttga
    19321 ttacttgatt tggatataaa tctcctaact tatgcatctc ttccctttga gtctccgtga
    19381 tcgtctgcgc taacttttgt atttcttgat tgactccttc aaatttgaca ggaacttttt
    19441 tcgccacacc tgccacataa aactgttctt tcttttcgat acgaaattcc atcgattttc
    19501 ctcctctgac atcaataaaa aatgtcaagc gtggaaaaga tttttgtatg ccgtatctgc
    19561 tgatttctga aggcagatat cctgaccaat cacgaaaagc tcttgaaaaa ccttcgactg
    19621 tttcatatcc atatctaaac gccgtttctg tcactcttga tccatctaga agatcgcgat
    19681 tagccaaagc caatctacgg tttttgatat agtccattag cgacatccct gcaataaacg
    19741 taaagatgcg ttttaattga tattcagaga ttcctgtatt ttcggctatt attttatagg
    19801 aaagtccttc tgtcaaatgt tcttcgatgt aatcgatcaa ttggttcaga tctttaagca
    19861 tatttatctt cctccttgat tgccttttta tcatattatc aaagaaagtc aattacttga
    19921 tgaatcagga accaatttag tcagatgtag aaaatgttgt atggatctaa agaaaattct
    19981 caagcagcgt ttcgtaacgg ataattggta ttatctgcct atctatgttt tacctttaga
    20041 aaaataaatt ttggggaaga cagattctaa gtaaacaaag cggtaaaaat atcttttatt
    20101 cccttagtta atccgcttac tacctactgt acaaagcaaa ttgttgttca aactgctgat
    20161 cagaacgctg cttggatttt tcttt
//
LOCUS       DADQDV010000055        20108 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.056, whole genome shotgun sequence.
ACCESSION   DADQDV010000055 DADQDV010000000
VERSION     DADQDV010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 20108)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20108)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20108
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.056"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..210)
                     /locus_tag="J8S10_002066"
     CDS             complement(<1..210)
                     /locus_tag="J8S10_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAZ9630646.1"
                     /translation="MDTITPTNFKENIGKVLQEVVHSNSEIEITRDSKNGLNDGVIMI
                     SKRKWELLQEELYLQRTGTWAYVSDL"
     gene            complement(309..623)
                     /locus_tag="J8S10_002067"
     CDS             complement(309..623)
                     /locus_tag="J8S10_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630647.1"
                     /translation="MAEENKVVPFETLVINKEEFEQLFLDFFIQYDMIYDFSSSLDLF
                     ELEAEIIENSREKNGKIIISVEKFNELFSQTFEIDPDYYQPQEVFREFRNKIIGFSQT
                     TK"
     gene            complement(691..1185)
                     /locus_tag="J8S10_002068"
     CDS             complement(691..1185)
                     /locus_tag="J8S10_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630648.1"
                     /translation="MFKVYFPFQWLVKGILLVLLGLILFGSYLTIKARHFPEEKPIKI
                     VTKDLKIGETYQADGVELTFKNIEVTEKRNEFAQHDRVLQVTYTLINDTENPIRPQQW
                     SIENKDGEELYEYDMILDNPEYIESGKEETVNYYYELPIERQDYQIVVRRENGYIVGL
                     PFTL"
     gene            complement(1178..1492)
                     /locus_tag="J8S10_002069"
     CDS             complement(1178..1492)
                     /locus_tag="J8S10_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630649.1"
                     /translation="MNYPYFKVSASEETKEIFNNFYNQNKGIFGSKANMFRVMVSNLP
                     VLASPSNNKFNDPESIKFEQKISELESMISNEVIEKLDDIDQKLSYSLKNKYKTEEKK
                     DV"
     gene            complement(1708..3099)
                     /locus_tag="J8S10_002070"
     CDS             complement(1708..3099)
                     /locus_tag="J8S10_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HAZ9630650.1"
                     /translation="MGATITSKGRKKNLSSLLQYAANPSKKEKCVAVSGINCSDDSEE
                     ALQEMNLVRTKMNKSKDIAQAFHVIHSFDKSTSKELSIDKMHEIAVEFAEKAFPNSQI
                     IVASHNDKDHFHSHLVINNINMETCKRLRIDPKDLELMRKINDQVLNEHGLESVNNEY
                     YENLEKRTNLYSNDPSKMKYGKINYQEFVQNAIEATLEKCEVNSFEDFSDHLAKEYNI
                     EVYQFSKTNNKLGYVLYKQGVNFYERRGELITLGRDKQSRKEKSQYVERTFSARKLGK
                     RYSFESVSEQLEKNLEESHIKNFFNMEREQVMSLISGVNYKTGELNVPFVELDSIAQK
                     QFSDREGDEKFIKYDDFLREVDKHFVNTMSLEDDQEYTIKLHTDVNPQTLRSAKSKTI
                     SIKKTDQKELFLPAKGFENCSHTPSAKQIHYQISRIMNDDVKMYRAKKDYEFTQQMIE
                     NQQKRQQNFEMEF"
     gene            complement(3084..3695)
                     /gene="mobC"
                     /locus_tag="J8S10_002071"
     CDS             complement(3084..3695)
                     /gene="mobC"
                     /locus_tag="J8S10_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HAZ9630651.1"
                     /translation="MDDKQKMYEKNRKHSEALNFRVDKKTYLELTLIAKQRGISRADV
                     CRERLKGLKYEPPLLAEDDRVVLTKQLNQIGNNLNQAVKALNIIAKYFREESEDKKEK
                     SLHFSFDASRYNIFKDELANSIAKKLMISYPDDIFLESNRSAPSFFKLSEVEKEYFEY
                     WIEKQTRPGTKEEYSQKVDRNLIHSIQIIASLKDEVKQLWELL"
     gene            complement(3699..3896)
                     /locus_tag="J8S10_002072"
     CDS             complement(3699..3896)
                     /locus_tag="J8S10_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630652.1"
                     /translation="MQLILKISTHDFLELDELCESVKNATNEKITVTNYIELMIQEEL
                     KMKNEIESNFKCCSLEKNVRG"
     gene            complement(3887..6565)
                     /locus_tag="J8S10_002073"
     CDS             complement(3887..6565)
                     /locus_tag="J8S10_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630653.1"
                     /translation="MKIIEKKIANKKINWLVVNFLVLIAMIIFTSNIAHASIFNWFDD
                     TKSQTEFLNNSLYRPYLKKYNGDFLSQFGIWLGWAVVKGMFTVTDSIQNMIPDVLDLF
                     NFIESTGLNNVYQSAVNTIVIGLMILSLMFVGYKMITGKGTVDLKSVGMNVVMSIALI
                     LLMPTMISSGIQFAKTFYKDSTTITNSDDGVAWSLIKQGVTDLAYINKTDQYSSIDKT
                     EDRNNLTRKNFQQTDLTQVLTDKVIDKLEKENPIADNLRYELVENSNNEFVATKFSDN
                     FLSTFSDSLKSGYYRYQANLWGISIGLTALAIAYVFSAFVIITAILELAFKRVLGVLV
                     FATDIETGQRSKVVLSDILQCYLTVGFQGFGLSMFAMFINFLNSGQGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSNGFNRAKGSGE
                     GEDRKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERATKPFKSMRDI
                     ANDTKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSVPTRLSDRKDGAKVEN
                     ADRIMSSSERMREAMKNNAESNNNPASAIQQKVQQDIEERKNAMHGQAKSAEELINQK
                     RHEAKYTPEAMNREEIMLRKRVEGRTGANIDGKEALTKERIQEAKNSNTGLEKLVKEN
                     PQNSTSSHGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNAQGTKTIDVRENLQSS
                     STSQPKTVDVRENVQNSTSSQGFKSVDVRENVQGSSASQPKTVDVRENVQSSTSSQGF
                     KTVDVRENIQKDSGEMKEKTQKINIVEDRKSAKKFDSNHETVIIDSEIRENDKGSKSR
                     RRFTYEDNELFRDTLNDPNPLFDNLLRNKRGGLSCN"
     gene            complement(6552..6770)
                     /locus_tag="J8S10_002074"
     CDS             complement(6552..6770)
                     /locus_tag="J8S10_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630654.1"
                     /translation="MIKNRLIDQVWCLDQNTDSLELIETICFNTIVLDLRAENDNCVT
                     HVIINQKMAQKLSESLRKWAKGGNDENN"
     gene            complement(6846..7898)
                     /locus_tag="J8S10_002075"
     CDS             complement(6846..7898)
                     /locus_tag="J8S10_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HAZ9630655.1"
                     /translation="MNEKEVESLVEKQGYSNSDIYAELYYQYPIFLNVNEKYKKMKLS
                     SKLVYMLLKDRNRLSLKNNLYDENQKIFLIFEIKNLVEISGMSKNTILSALDELQKVK
                     LLVKRKNGFNKSKMQMFPNFYYLLKPVLCKDDVYKINKITHQENRQKNLIVQNLNYGT
                     NQYSVDSSKFELCDTSMKTRDKNNFADSSKNELELYKSYKDSKDIKESHNDDLLESLS
                     TKNNKLDEELIETFIEENLLKQIWGESIVNCLKLASNSDYRQFDNWYKKFKYAIRSAE
                     KEQKIQLKIIYEICNNKYFVDHVREQLSMTLRDLIRRAKTDHRIKQKDDYIFASLKNK
                     ALELIELQISEGIDKQ"
     gene            complement(8051..8377)
                     /locus_tag="J8S10_002076"
     CDS             complement(8051..8377)
                     /locus_tag="J8S10_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630656.1"
                     /translation="MASWLIEEIENERRKIMDAGITVMLDKQQTNQLKNYVFEMTKEA
                     IDQARIDTGLERPFLKGKEMAKYLNVSYTTFLKFKRMGLPVILLEKMELFSKEECKKW
                     ILSHQI"
     gene            complement(8389..8589)
                     /locus_tag="J8S10_002077"
     CDS             complement(8389..8589)
                     /locus_tag="J8S10_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAZ9630657.1"
                     /translation="MITLNDQFIRSLRRHRADLILTKNDAAKLIGINRKTYVKIENGS
                     KESIRASTYQKLVNWLLNDLKI"
     gene            8664..9314
                     /locus_tag="J8S10_002078"
     CDS             8664..9314
                     /locus_tag="J8S10_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAZ9630658.1"
                     /translation="MSIKVLLNLWFSCYNSLEFTIGGVTLNRIKFYIDSSKKTIKQIS
                     TETGINYTTLTNYYRGERNPRNTETWNILADYFHVPVSYLMGLDETNSIEQPNLDRIK
                     TARLEKKDKIVKNIASLDSDYFTELSNLYFSMTSLLEVKLQEDDSDFLFLKSILEDSF
                     EYTILFAKQKKFINKALNLNIDERKELESELFGNLTQVQVNNLKREITARLISKLQ"
     gene            9369..10535
                     /locus_tag="J8S10_002079"
     CDS             9369..10535
                     /locus_tag="J8S10_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAZ9630659.1"
                     /translation="MSIQKYTTKSGARYSVRLYVRKDENGKQEYYVKKGFKTEKEAKL
                     HEARKKVEIEDTGYHKPSNDLFITVYEEWLPSYRNRVQETTYQRTKDLFRLHILPKFG
                     NKSISKITPVHCQNAVNEWALKFKNIKQLKSYSSQIFEYAIFAELLHRNPMANTNLPK
                     REKKENENYFSLEELKAFWDILNKEEPLKHILIFQLLITTGIRKGELAALHWSDIYFE
                     EQLMYVRKSYATIRNEEKNARRKTVRIQKNTKNISSERILPIDAQTIEMLKIWKKEQA
                     RELLQFGINTNTKNQLIFTYVNADGDINQPLHADYSNNILKRLEKKYKFKHVTIHGFR
                     HTHATLLLEGGASIKETQDRLGHKNAETTLNTYSHVTEKAQRNALEKFIAYTGL"
     gene            10952..14179
                     /gene="fss3"
                     /locus_tag="J8S10_002080"
     CDS             10952..14179
                     /gene="fss3"
                     /locus_tag="J8S10_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HAZ9630660.1"
                     /translation="MYKKQKKKLCVLTILSLAVQSIVGAIAPTIAFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGVKQDIFCVEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIADYQKKPSFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENTANIDYRVN
                     GNQLIISPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTVKIDVE
                     MEGSLKIKKVDKESGDIIPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTATIKAGETISVTSKNTREKGQIILDKTGIETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDEKGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELNYVNQTVALVTSNVKGQNQEITGETTLTKEDKDTGHETQGKAEFKRAEYTL
                     FTVKDGKAVKWTENFKPELLKGTKASDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYTLDETKYPVSIKKVDDSEKNAVITRDVAAKEQVIRFGFDFFKFAGSTTGTAETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDYTKSDYIFTITEKGQKQPIKTVTVPYGNLTNENFSVSLNR
                     LMLYDLPEEEDSLTSLATWKEGDKELTTLDSTELVDKLSYNLHEIKEDWYIVAQAIDV
                     DATKAAQEKDKKAKPVAIAETTATLANKEKTGTWEILHKLTVEQVLDKTIVLFNYVYE
                     SKEAYEAGDEPVAKDASLNNQAQTVNCMVERHVSIQTKAHLEEGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALFPDGTSKEIWKSGKIDYEVNDKEFTKTVLAEKVDT
                     SKYPEGTSFTFKEINYDKDGNINGKHNEDLKEKSQTLTPKKVPTTPSTPEQSEMPTVP
                     SGSQESSPTVKAFPQTGEKTSNVLLFIGFSLIFATAGYYFWNRRN"
     gene            14291..14605
                     /locus_tag="J8S10_002081"
     CDS             14291..14605
                     /locus_tag="J8S10_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAZ9630661.1"
                     /translation="MELKFVVPDMVETFGKLTYGGEGEVLSEGYGRNTTIVGRSYHLF
                     SNKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLIAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            14618..14992
                     /locus_tag="J8S10_002082"
     CDS             14618..14992
                     /locus_tag="J8S10_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAZ9630662.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQLNQGKPTNQNEGKK"
     gene            15002..15346
                     /locus_tag="J8S10_002083"
     CDS             15002..15346
                     /locus_tag="J8S10_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HAZ9630663.1"
                     /translation="MEINVEHILDCLDQFGKGELTEEQLTNALTYDEKMFLIMHQGLL
                     EVGNDAKEDFDVLDWLGEEESFFMVVEVNESLCRQAESVLEEIDVEMPDAIERFLKQL
                     VETKQLPVVVND"
     gene            15415..16431
                     /locus_tag="J8S10_002084"
     CDS             15415..16431
                     /locus_tag="J8S10_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HAZ9630664.1"
                     /translation="MYKGHRIRAGDQHLIYHFVLGWLIFLFIGWMSVFYLQELRQFDI
                     SKVSFSTSEIGWSMKDVICLLGSLALSGSMMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQGEGFFKDLNSSWTKESISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LENKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIEEIVAENGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIQALLKSDAELFILDPKNADLADLGTIMPHVYSQK
                     EEISECVEDFYERMIARSRSMKEMPNYKTGENYAYLGLPPNFLIFDEYVAYMGANRFP
                     TSIE"
     gene            17025..18899
                     /gene="ltrA"
                     /locus_tag="J8S10_002085"
     CDS             17025..18899
                     /gene="ltrA"
                     /locus_tag="J8S10_002085"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HAZ9630665.1"
                     /translation="MNVETDEVQGSGKNVGKSVMEVPRLNTKIRYWEYYDLQETFDQL
                     FTQSRNGKKFYQLYELIISENNILLAYRTIKANKGSSTPGTDSFTIDNYKEMNQAEFI
                     HLILSHLENYKPKSIKRVMIPKPNGEKRPLGIPCMIDRMIQQMFKQILEPICEAKFYE
                     HSYGFRPLRSAKHALGRIMYLINISKMHYAVDIDIKGFFDNVNHRLLIKQLWNIGICD
                     KQVLAILSKSLKSPIQGEGIPSKGTIQGGIISPLLSNVVLNDLDHWVSKQWHTFETKY
                     PYTKGYNKFRALRDTNLKQGYIVRYADDFKIMTNDYPTALKWFHAVKLYLKDRLKLDI
                     SNEKSKIVNLRKCKSEFLGFAICVKQKGKKWVCNSRISNKKKDQIKEEIKQRIKDIQK
                     SPTAQNALLFNALVLGVHNYFRYATHINLDLNRMNYVLSFTTYNRLSNCSTRCYPNKA
                     SPTYKKFYSTTMKTYKVAGVYLYPLCDVSTKTIYGFNTEDTPFTPFGRQRLEHKSLQS
                     LVFQELRKLMESKIPNRTVEYLDSRISRYSMKSGKCEITKQFLPAKAVHCHHYLPKSL
                     GGDDKFDNLRIIHKDIHLLIHTTNKMIIDHYVHELKLVPEQIAKINLYRKMCNLQNIQ
                     "
     gene            19025..19381
                     /locus_tag="J8S10_002086"
     CDS             19025..19381
                     /locus_tag="J8S10_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HAZ9630666.1"
                     /translation="MILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRV
                     ALGRMSELGYSMMFGEVDKNFFMKRIKGRGYVDTGGSVISEFYTPLVPKGYDFLREIS
                     NIVGLTVHTERENNSV"
     gene            19426..>20108
                     /locus_tag="J8S10_002087"
     CDS             19426..>20108
                     /locus_tag="J8S10_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HAZ9630667.1"
                     /translation="MTFLDLFAGIGGFRLGMEQAGHQCIGFCEIDEFARRSYKAIHDT
                     RKEVEMHDITSVSDEFVRSLGPVDILCGGFPCQAFSIAGKRQGFSDTRGTLFFEIARF
                     ATLLQPKFLFLENVRGLLNHEGGATFETILRTLDGLGYDVEWQVLNSKAYVPQSRERI
                     FLIGHSRDACTEQVFPIIGSSSTSDQNIRNLVNINPSNRGMGGQVYGSDDVAPTLTGD
                     EGIKIALPV"
BASE COUNT         6463 a         3579 c         3492 g         6574 t
ORIGIN      
        1 taaatcagat acataagccc atgtacccgt tcgttgtaaa taaagttctt cttgtaacaa
       61 ctcccatttt ctcttagaaa tcataatgac gccatcgttc aatccatttt tagaatccct
      121 agtaatttct atttcagaat ttgaatgaac tacttcttgc aacactttac ctatattttc
      181 tttgaagttt gttggagtaa tagtatccaa aatgaatacc tctcttctct atacctctat
      241 tatgaagtgc ccataaaata aagcaagcgt tgaggaataa ttctatcaac acttgcttta
      301 ttaagctttc attttgtagt ttgactaaaa ccaataatct tatttctaaa ctctcgaaaa
      361 acttcttgtg gttgataata gtctggatct atttcaaatg tttgtgagaa taattcattg
      421 aatttttcta ctgaaataat gattttacca ttcttctctc gactgttttc tattatttct
      481 gcttctaatt caaataaatc tagtgacgaa ctaaaatcat aaatcatgtc atattgaata
      541 aaaaaatcaa gaaaaagttg ctcaaactct tccttattta tcactaatgt ttcaaacgga
      601 acaactttat tttcctcagc cattctccca gttccatttt caaaaatcac aaaactgata
      661 ttaccttaaa aactactaac aaaataaaac ttataaagta aatggcaacc caactatgta
      721 accattctct ctacgtacta cgatttggta gtcctgcctt tcaatcggta attcataata
      781 gtaatttact gtttcttctt tgccactttc aatatactct ggattatcca atatcatatc
      841 atactcataa agttcttcac catccttatt ttcaatcgac cattgttgtg gacgtatcgg
      901 attttctgta tcatttataa gtgtataggt cacttgtaat acacgatcat gttgtgcaaa
      961 ttcatttctt ttttcggtca cttcaatatt tttaaatgtt agttcaaccc catctgcctg
     1021 ataagtttca cctattttta aatcttttgt tacaattttt attggctttt cttctggaaa
     1081 atgtctggct ttaattgtta gataacttcc aaaaagaatc aatcctagta gcactaaaag
     1141 aattccttta acgagccact gaaacgggaa gtaaacttta aacatctttt ttctcctccg
     1201 ttttgtattt gttttttaga gaatacgata acttttgatc aatgtcatcc agcttttcaa
     1261 ttacttcatt acttatcatt gattctagtt ctgaaatttt ttgttcaaat ttaatgcttt
     1321 caggatcatt aaatttatta tttgatggac tagctaacac tggtaaattt gaaaccataa
     1381 cacgaaacat atttgccttt gaaccaaaaa ttcctttgtt ttggttgtaa aaattgttga
     1441 atatttcttt agtttcttct gaagccgaga ctttaaaata tggatagttc atttttttct
     1501 tccacctttc tttttttggg agggagtctg tagggagctt gctccctcag agatttaccc
     1561 gccatctgac ttgccagaaa gtagcctagc gtgagcgggg cggattgact ggcaagtaga
     1621 tgggtagctg gcgtatgtcc taaaaactgc ttctttccaa gcaactcttc ataggcaaaa
     1681 aactggaaag tccactaaca agcccattca gaattccatt tcaaaatttt gttgcctttt
     1741 ttgctgattt tcaatcattt gttgtgtgaa ttcataatcc tttttagcac gatacatttt
     1801 tacatcgtca ttcattatgc gactgatttg atagtgaatc tgtttagcag aaggtgtatg
     1861 agaacaattt tcaaaaccct ttgccggtag aaataactct ttctgatcag tctttttaat
     1921 agaaattgtt ttacttttcg cactacgtaa agtttgagga ttcacatccg tatgaagttt
     1981 aatcgtgtat tcttgatcat cttctaaaga cattgtattt acaaaatgct tgtctacctc
     2041 tcgcaagaag tcatcatatt taatgaattt ttcatcgcct tcacggtcgc taaattgctt
     2101 ttgtgcgatg gaatctaatt ccacaaacgg tacatttaac tcaccagttt tgtaatttac
     2161 tccactaatt agcgacataa cttgctctct ttccatatta aaaaaatttt ttatatgtga
     2221 ttcttctaaa ttcttttcaa gttgttcaga aacagattca aatgaatatc ttttccctaa
     2281 ctttcttgca ctaaaagtac gttcgacata ctgacttttt tcttttctag attgtttatc
     2341 tcttcctaaa gtaattaact cacctctacg ctcatagaaa tttacacctt gtttgtaaag
     2401 aacatagcca agtttgttat ttgtttttga aaattgataa acttcaatgt tatattcttt
     2461 tgccaaatga tccgaaaaat cttcaaaaga attcacttcg catttttcca acgttgcttc
     2521 gatcgcattt tgcacaaact cttgataatt aatttttcca tatttcatct tagaaggatc
     2581 gtttgaataa agattggttc tcttttctaa gttttcatag tactcattat tcactgattc
     2641 aagaccatgt tcattgagga cttgatcgtt aatttttcgc attagttcta aatctttagg
     2701 gtcaatacgc aaccttttac atgtttccat gttaatatta ttaatgacaa gatgactatg
     2761 aaaatgatct ttatcattgt gacttgcaac aatgatttgc gaatttggaa aagctttctc
     2821 tgcaaattcg acagctattt cgtgcatttt atcaatactt aactctttag aagtactctt
     2881 atcaaacgaa tgaataacat gaaacgcttg tgctatatct ttagatttat tcatcttggt
     2941 acgtactaaa ttcatttctt gcagtgcttc ctcactatca tcactacaat ttattcctga
     3001 gactgcaaca catttttctt tttttgaagg attagctgca tattgtaata gcgaggataa
     3061 atttttcttg cgtcctttcg atgttatagt agctcccaaa gttgtttcac ctcatctttt
     3121 aaacttgcaa taatctgaat tgagtgaatt aaattccgat caactttttg ggaatactct
     3181 tctttcgtac ccggtctagt ttgcttttct atccaatatt cgaaatattc tttttctact
     3241 tctgataatt taaaaaaaga gggggcactc cgattggact ccaaaaaaat gtcatctgga
     3301 taactaatca tcaacttttt tgctatgcta ttcgcaagtt catctttaaa aatgttgtaa
     3361 cggctagcat caaaactaaa atgtaggctc ttttcttttt tatcttcaga ttcttctcta
     3421 aaatatttag caatgatatt taatgccttt accgcttgat tcaaattgtt accaatttga
     3481 tttaactgtt tggttaaaac taccctatca tcttcagcta acaacggcgg ttcatatttg
     3541 agtcccttta accgctcacg gcaaacgtct gctctagaaa ttcccctttg ttttgcaatc
     3601 aatgtcagtt caagataagt ctttttatcg acacgaaaat ttaaggcctc actatgtttg
     3661 cgattttttt cgtacatttt ttgtttatca tccattgatt atcccctcac atttttttct
     3721 agagagcaac atttgaaatt gctctctatt tcatttttca tctttaattc ttcttgaatc
     3781 atcagttcaa tataattagt gaccgtgatt ttttcatttg ttgcgttctt tactgattca
     3841 cataattcgt caagttctaa gaaatcatgc gtactaatct ttagaattaa ttgcatgaca
     3901 atccccccct tttatttctt aataaattat cgaaaagtgg attaggatca ttaagtgtat
     3961 ctctgaataa ctcattgtct tcataagtga atcttcgtct tgattttgat cccttatcat
     4021 tttcacggat ttcactatca ataatcactg tttcatgatt tgaatcaaat tttttcgctg
     4081 actttctgtc ttcaacgata ttgatttttt gtgttttttc tttcatttct ccactatctt
     4141 tttgaatgtt ctcccgaaca tctactgttt tgaatccttg actacttgta gaactttgta
     4201 cattttctcg gacatctact gtttttggtt gacttgcact gctaccttgc acattctctc
     4261 ggacatccac tgatttaaac ccttgactac ttgtagaatt ttgtacattt tctcgaacat
     4321 ctactgtttt tggttgactt gtactgctac tttgcagatt ttctcgaaca tcaattgtct
     4381 tagtaccttg agcatttgaa gaactttgta aattctctct tacatcaaca ttccgtccaa
     4441 catgaccatt cagtgaacct tgaatatttt ctcggacatc tactgatcgg ccaccatgac
     4501 tacttgtaga attttgtgga ttttctttga ctaatttttc taatcctgta tttgaatttt
     4561 tagcttcttg aattctttct ttggtcaacg cttcttttcc gtcaatatta gcgcctgtcc
     4621 gcccttctac acgtttcctt aacattattt cctcgcgatt cattgcttca ggcgtgtatt
     4681 tcgcttcatg acgcttctga ttaattaatt cttcagcaga cttagcttga ccgtgcatag
     4741 catttttacg ttcttcaata tcttgttgga ctttttgctg aattgcgctt gcaggattat
     4801 tattcgattc agcattattt ttcattgctt cacgcatacg ttcagaacta gacataattc
     4861 tatcggcatt ttcaacttta gcaccatctt ttctatctga aagacgtgtt ggcacggaat
     4921 cagcatattt tccagtttca tcttctttat ttttagctaa cataggtttg ctatttttat
     4981 taatagcgga cactgtacca tcatctaaac cttctttaaa cttattcttg gtatcattag
     5041 ctatatcacg catactctta aatggttttg ttgctctttc actagccatt gtagctccat
     5101 ctgaagctaa accggataat ccacgttcat gggcatatcc caaagctctt ccagttttgc
     5161 cagctttttt tgatagagtt tcgccgaaat tcttttctgg ttttcgatct tctccttctc
     5221 cgcttccttt agcacgatta aatccatttg atccttttct aaacagcatt gcgcccattc
     5281 caaaagcaga agcaagttgc ccatagcctt ctttgagtcc aatatcaaca ccaaagtatc
     5341 tcatgactgt tccactgcct ttgattaaaa caaaaacggc acagatataa gcaattgttt
     5401 ttataaaaat atttgttgag ataccttgtc ctgagttcag aaaattgata aacatagcaa
     5461 acattgataa cccaaatcct tgaaacccaa cagttaagta acattgtaga atatctgata
     5521 gaacaacttt tgaacgctgt cctgtctcaa tatctgttgc aaaaacaaga acacctaaca
     5581 cacgtttaaa tgcaagttct agtattgctg taatgatcac aaacgcgctg aacacatagg
     5641 cgattgctaa cgctgtcaac ccaattgaaa tcccccatag atttgcttgg tatcggtaat
     5701 agcctgattt caagctatca gaaaatgttg ataagaagtt gtcagaaaac tttgtagcaa
     5761 caaattcatt attagaattt tcaactaatt cataacgaag attgtccgca attggatttt
     5821 ctttttccaa tttatcaatc actttatccg ttaacacttg tgtgagatcc gtctgttgaa
     5881 aattttttcg tgttaaatta tttcgatcct ccgttttatc aatgcttgag tactgatctg
     5941 ttttattaat atatgctaaa tctgttactc cttgttttat caatgaccaa gcgactccgt
     6001 catctgaatt tgtaatcgta gtagagtcct tataaaatgt tttagcaaat tgaataccac
     6061 tagaaatcat ggttggcatt aaaagtatta atgctataga catcactacg ttcattccaa
     6121 ccgattttaa atccactgtt ccttttccag taatcatttt gtaaccaaca aacatcaatg
     6181 aaaggatcat taatccaatg acaattgtat ttacggctga ttgataaaca ttatttagcc
     6241 ctgtactttc aatgaaattg aacaaatcca gcacatctgg aatcatattt tgaatcgaat
     6301 ctgtcacagt aaacatgcct tttaccacag cccatccgag ccaaatcccg aactgactaa
     6361 ggaaatctcc attgtacttt tttaggtaag gtctataaag agaattattc aaaaactctg
     6421 tttgactttt tgtgtcatca aaccaattga aaatactcgc atgagcaata ttacttgtaa
     6481 aaataatcat agctatcaga acaagaaaat taacaaccaa ccaatttatt tttttattgg
     6541 caatcttttt ttcaattatt ttcatcgtta cctcccttag cccattttct gaggctctca
     6601 gagagcttct gagccatttt ttgattaatt atgacatgag ttacacaatt atcattttca
     6661 gctcttaaat cgagaactat agtgttgaag caaatagtct cgattaattc gagactatct
     6721 gtattttgat ctagacacca aacttgatct attaaacgat ttttaatcaa aataacccct
     6781 cctatattca aagttctcaa atgaagtgga gatacccctc catttcattt gactcaattc
     6841 tattcttatt gcttatctat tccttcgctg atttgcaatt caattagttc taacgcttta
     6901 ttttttagag aagcaaagat ataatcgtct ttttgtttga tacgatgatc tgtttttgct
     6961 cttcgtatca agtcacgtaa agtcattgat agctgttctc taacatgatc tacaaaatac
     7021 ttgttattac aaatttcata gataattttc agttgaattt tttgttcttt ttcagcagat
     7081 ctaatcgcat atttgaattt tttgtaccag ttgtcgaatt gacgataatc actattgcta
     7141 gccagtttta agcaattcac aatactttct ccccatattt gtttaagaag attttcttca
     7201 ataaatgttt cgatcaattc ttcatctaat ttattatttt tagttgaaag tgattcaaga
     7261 agatcatcat tatgtgattc tttaatatct ttactatctt tataagactt atataattct
     7321 agttcatttt ttgaactatc agcaaaattg tttttgtctc ttgttttcat tgatgtgtcg
     7381 catagttcaa attttgaact atcaacagaa tattgatttg ttccatagtt caaattttga
     7441 actatcaagt ttttttgtct attttcttga tgggttatct tattaatttt ataaacatca
     7501 tctttgcaca gaacaggctt taacaaataa taaaaatttg ggaacatttg cattttactt
     7561 ttattgaagc cattttttct tttcacaaga agtttaactt tttgaagttc atctagtgct
     7621 gataagattg tattttttga cattcccgaa atttctacga gatttttgat ttcaaatatc
     7681 aaaaaaattt tttgattctc atcatacaag ttatttttca atgaaagtct atttctatct
     7741 tttagtaaca tataaactaa cttagaactt agtttcattt tcttatattt ttcatttacg
     7801 tttaaaaaaa taggatattg atagtataat tctgcatata tatcagaatt agaatagcct
     7861 tgcttttcaa ctaagctttc aacttctttt tcattcattg tcacacctgc ttctgatttt
     7921 atttgctata atagattcaa ataaagtttt ctcagaactt tattattgag tgttcccccg
     7981 atctgcaaac tgacgggaac actcttttta attttttcta cttcatcaaa tttaaaaaac
     8041 gaggtgtttt ttaaatttga tgactcaata tccatttttt gcattcttct tttgaaaaca
     8101 actccatttt ttctaataaa ataactggca atcccattct tttaaatttc aaaaaagttg
     8161 tatatgatac attcaaatat ttagccatct cttttccttt tagaaatggt ctttctaatc
     8221 cggtatcaat tcttgcttga tcaatagcct cttttgtcat ttcaaaaaca taatttttca
     8281 attgattcgt ttgttgttta tctaacatta ctgtaattcc tgcatccatt atttttctcc
     8341 tctcattttc tatttcttca atcagccaac tcgccaagtt gtatttattt agattttcaa
     8401 atcattaagt aaccaattta ccaacttttg ataagtagat gctctaatac tttctttgct
     8461 cccattttcg attttgacat atgttttccg atttatacct atcaattttg ctgcatcgtt
     8521 tttagtaagt ataagatcgg ctctatgtct tcttaagctt ctaatgaatt gatcattaag
     8581 agttatcatt cagcgcctcc tttcaaatta ttcactttgt ggtttttatc ttaataagca
     8641 cattttaaac cacaaaacga gtaatatcaa ttaaagtatt actcaatttg tggttttcat
     8701 gctataatag tttggaattt actatagggg gcgttacttt gaatagaata aaattttata
     8761 ttgattccag taaaaagacc attaaacaaa ttagtacaga aactggtatt aactatacaa
     8821 ctcttacgaa ctattaccgt ggtgagcgaa atcctagaaa tactgaaaca tggaatatcc
     8881 ttgctgatta tttccatgtt cctgtaagtt atttgatggg attagacgaa acaaattcca
     8941 tagaacaacc taatcttgat agaataaaaa ctgctcgttt agaaaaaaag gacaaaatag
     9001 tcaagaatat tgccagtctt gactcagatt attttactga attatctaat ctatactttt
     9061 ccatgacttc tttacttgaa gtcaaacttc aagaagatga ctccgacttt ctttttttaa
     9121 aaagtattct agaggactcc tttgaataca cgattctatt tgccaaacaa aagaagttta
     9181 ttaataaagc tttaaactta aatatcgatg aaagaaaaga gttagaatct gagttatttg
     9241 gcaacttaac ccaagtacag gttaacaatc taaaaagaga gataacagct cgattaatat
     9301 caaaacttca ataaaactaa ttattcaatc agccaactcg ccaagttatc agattggaga
     9361 gattagttat gtcaatacaa aagtacacaa caaaaagcgg tgcacgatat agtgtccgct
     9421 tgtatgttcg taaagatgaa aatggaaagc aagaatacta tgtaaaaaaa gggtttaaaa
     9481 ctgaaaaaga agccaagtta cacgaagcaa gaaaaaaggt cgagattgaa gataccggct
     9541 atcataagcc ttctaatgac ttgtttataa cagtgtatga agaatggttg ccttcttata
     9601 ggaatcgtgt acaagaaacg acatatcaac gtacaaaaga ccttttccgc ttgcatatac
     9661 taccaaaatt cgggaataag tccatttcta agattactcc tgttcactgt cagaatgcag
     9721 tcaatgaatg ggctttaaaa ttcaagaata tcaaacagct taagtcttac agctctcaaa
     9781 tatttgagta tgccattttt gcagagctat tacaccgaaa tcctatggca aatacaaatc
     9841 taccaaagcg ggaaaagaaa gaaaatgaaa attacttttc attagaagaa ctaaaagctt
     9901 tttgggatat tctcaataaa gaagagcctt taaaacatat tttaatcttc cagcttttga
     9961 ttactactgg tatacgtaaa ggagagctag ctgctcttca ttggtctgac atttattttg
    10021 aagaacagct aatgtatgtt agaaagagct atgcaactat tcgaaatgaa gagaagaatg
    10081 caagaagaaa aactgtcagg attcaaaaaa atacaaaaaa tatatcttcc gaacgaatat
    10141 taccaattga tgcacaaact attgaaatgt taaaaatctg gaaaaaagaa caagctcgag
    10201 agcttttgca gtttggcata aatacaaata caaaaaatca acttatcttt acctatgtaa
    10261 atgcagacgg tgacattaat caacctttgc atgcggacta ttcaaataat atattgaaac
    10321 gtttagagaa gaaatataaa tttaagcacg ttactattca tggattccgg cacactcacg
    10381 ctactcttct actagaaggt ggagcaagta tcaaagaaac acaagatcga ttgggtcata
    10441 aaaatgctga aactaccctt aacacttatt ctcatgttac tgaaaaagct caacgaaatg
    10501 cgttagaaaa attcattgct tacactggtt tataatattg tcattacctt tctcattacc
    10561 agaacgaaaa aaagacacct tctcgcaatg agaaagtgtc tgaaatcgtt ggtataacaa
    10621 cgattaacgt tttgaaaact gtgaagcttt acgtgctttc ttaagacctg gttttttctt
    10681 cgtatcattg aataagtttg aaaagccttg atttataaag gtttttccgt aaatatattt
    10741 tgttatattt gattaaattt gaaatgtttg tgttctaaaa tgtgttctaa tttaaaggca
    10801 gtatatttcg tattttatat taaattttta ggctcattca ttctcaaatc cattctattt
    10861 agtcaataaa tattttaaaa agactttata aacaaagatg ttcaagcgag catcttattt
    10921 ttttgtgcct aatttgaaag gagaacattt catgtataaa aaacaaaaaa agaaattatg
    10981 tgtattaact attttgagtt tggctgttca atcaattgta ggagcaattg ctcctacgat
    11041 tgcttttgct gatgaaatta cccatccaca aacggtaacc gtagaactag atttagcaca
    11101 tcaatatgct gttgaaggaa cttttagtga tggtcgtcca atgtcagaag tcactgttcc
    11161 gcattatgca gtgtacaacg gcgttaaaca agatattttc tgtgttgaac caggagtccc
    11221 gatttacaat gagttcactc ctggatatga gaagaacccg ttaccagata tgtccgataa
    11281 agccaaatta gtttccgttt tatggaaaaa agtaggtaca gatgcagata ctcatattgt
    11341 ggcacagaag atgatctggc aagaagttaa tgggtatacc cttcactcaa taaaacgatc
    11401 agatggtagt gccgtaaata tcgcagccat tgaggcaaaa atcaatcaag ccattgccga
    11461 ttatcagaag aaaccaagct tccataatag tacggctaaa acagtattag ggcaatcgac
    11521 tactgtgacg gatacgaata atctgaattt gtcagagttc gatgaggttg tggaaaatac
    11581 cgcaaacatt gattatcgtg tgaatggcaa tcagttgata atcagcccaa atgccaattc
    11641 aaaagaaagt ggtgtgttga cgcttaagaa atctgctggt accggaacac ctgtcgccta
    11701 taaaaaggct ggccaacaga ctttaatggc cggggcgatc gataagccga acacttatac
    11761 ggtcaaaatt gatgtggaaa tggagggttc tttgaagatt aaaaaagttg ataaagaatc
    11821 gggtgatatt ataccaggaa cggttttcca tttagacttt ggaaaaactt tacccgcaaa
    11881 agacgtgacc accgataaag aaggcattgc gaccttagat gagattcctc atggtacaaa
    11941 ggtaaccatt actgaaaaat cggtgccggc gccttatacg attgatacca cacccatgac
    12001 tgccacaatt aaagcaggtg aaaccatttc agtgacttca aaaaatacgc gagaaaaagg
    12061 tcaaattatt ctggataaaa ccggaattga aacagggagt gatctttgga acgataatta
    12121 ctctttagcg ggcaatacgt ttgccattcg caaggatagc ccaactggtg aaatcgtcca
    12181 agaaatgacc acggatgaaa aaggtcatgc agaaacacca aaagagattg ccaatgcgtt
    12241 ggaattggga acctactatg tgactgaaac caaggctagt catggctttg tgaatacttt
    12301 caaaccagta aaagtcgaat tgaattatgt caatcaaaca gtggctcttg ttaccagtaa
    12361 cgtaaaaggg caaaaccaag aaattactgg tgaaaccact ttgacaaaag aagacaaaga
    12421 taccggtcat gaaactcaag ggaaagctga gtttaaaaga gctgaataca ccttgtttac
    12481 tgttaaggat ggaaaagcgg tcaaatggac cgagaacttt aaaccagaat tgttgaaggg
    12541 aacgaaagct tctgatgaaa ccgtaacttt gactttagat gaaaagaatc aagttgccgt
    12601 taaacactta gcgattaatg agtattactg gcaagaaacc aaagcgcctg aaggatatac
    12661 cttggatgaa acaaagtatc ctgtatccat caaaaaggtg gatgatagcg aaaaaaatgc
    12721 tgtgattact cgagatgttg cggcaaaaga acaagtgatt cgctttggct ttgatttctt
    12781 taaatttgct ggatcaacta ctggcactgc cgaaactggc ttcaatgatc taacctttaa
    12841 agtgtcgcca ttggaaggaa ccaatgaaat caccggtgcc gaagatgaag cgaccacagc
    12901 ttataacgag caattagggt ttgatggtta tggcaagttt gaaaatcttc cttatgggga
    12961 ttatttactt gaagaagtag aagccccaga aggttttcaa aagattacgc cattagaaat
    13021 ccgttctact tttaaagaaa ataaagagga ttataccaag agtgattata tctttactat
    13081 taccgaaaaa gggcaaaagc aaccgattaa aacggtaacg gtcccttatg ggaatctaac
    13141 caatgagaat ttctcagtca gtttgaaccg tttgatgctt tatgatttgc ctgaggaaga
    13201 agatagctta acttctcttg cgacttggaa agaaggagat aaagaattga ctactcttga
    13261 ttctaccgag ctagtcgata aattgagcta taatctacat gaaatcaaag aagactggta
    13321 tatcgtagct caagccatcg atgtagatgc tacaaaagct gcccaagaaa aagataaaaa
    13381 agccaaaccg gtggcgattg cggaaacaac cgcaacttta gcgaataaag agaaaacagg
    13441 aacttgggag attctgcata aattaactgt cgaacaagtt ttagacaaga ccattgtctt
    13501 attcaactat gtgtatgaaa gcaaagaagc ctatgaagct ggtgatgagc cggtagcgaa
    13561 ggatgctagc ttgaacaatc aagcgcaaac tgttaattgt atggtggaac gtcatgtttc
    13621 catccaaacc aaagcgcact tagaagaagg ttctcagacc tttactcatg gtgacgtggt
    13681 agatatgttt gatgatgtat ccattaccca tgatgtacta gatggctcaa aagaagcttt
    13741 tgaaacaatt ctgtacgctt tatttccaga tggtacaagt aaagaaattt ggaaatctgg
    13801 caagattgat tacgaagtga atgacaaaga atttaccaaa accgtacttg cggaaaaagt
    13861 ggatacaagt aaatatccag aaggtacaag ttttaccttc aaagaaatta actatgacaa
    13921 agatgggaat atcaatggaa aacacaatga agatttgaaa gaaaaatctc aaactttaac
    13981 gcccaaaaaa gttccgacaa caccaagtac accagaacaa tctgaaatgc caactgttcc
    14041 aagtggctct caagaatcta gtcctacagt gaaggcattc cctcaaaccg gggagaaaac
    14101 ttccaatgtg ctactgttca ttggctttag cttgatcttt gcgacggctg gctattattt
    14161 ttggaatcgt cggaactaag gtgataagat gaaacatgta aatagtagaa aacaatacgc
    14221 gcgaccgcct cctaaaaaag tggtcgcgct atttttgtat tcaaaactaa caatgaaaag
    14281 aggaaaaaat atggaattga aatttgttgt accagatatg gtcgagacgt tcggaaaact
    14341 aacatacggt ggtgaaggtg aagttctatc ggaagggtat ggtcgaaata ctacaattgt
    14401 tggtcgaagt taccatctgt tttcaaataa acaacgggcc gatgatattg aagtggtggt
    14461 agctgcggaa gccggcgaaa aggattttga ccaagatcaa ccactaaaag ctgtaaatcc
    14521 ccacttaatt gccaaaggct atgaaattga gaatcgtggg tttaccgatt acgtgttgta
    14581 tgttgatgat ttagtgaaag cataggagga aaagaagatg agattaacag aaggtattgt
    14641 cgtagattca ggattaacct ttggcaagtt gcgtttttcc gcattacgtc gagaagtacg
    14701 caagcaaaat gaggacggaa cggttagtaa cgaggtaaaa gaacggacct ataatttgaa
    14761 atcctccgcg caaggtcgaa tgatccaagt cagtattcca gcaaatgtac ccttacgcga
    14821 gtttgcttat gatgcagagg tagagctggt caatccaatc gtggatacgg tcgccaatta
    14881 tgtttttcgg gaaggaacca ccgttaattg gtttatcaag gcagatgatt tagtcttgaa
    14941 acgacaactg aatcaaggaa aacctacgaa ccaaaatgaa ggaaagaaat aggtgaagaa
    15001 tatggaaatt aatgttgaac atattttaga ttgtctcgat caatttggca aaggtgagct
    15061 aacggaggaa caactcacta acgcattaac ctatgatgaa aaaatgtttc tgattatgca
    15121 tcaagggtta ctggaagtag gtaacgatgc caaagaagac tttgatgtac tggattggtt
    15181 aggggaagaa gagtctttct ttatggttgt cgaggtaaat gaaagtttat gtcggcaggc
    15241 agaatctgtt ttggaagaaa tcgatgtgga gatgccggat gccatcgaaa gatttttaaa
    15301 acaattagtg gaaacgaaac aacttcccgt agtagtaaat gactagcata actttttgaa
    15361 attgcccaat gaaatcctat tgggcttttt cgactggagg tggaaaccat caaaatgtac
    15421 aaaggacatc gcatacgcgc aggagatcaa cacttgattt atcactttgt tcttggctgg
    15481 ctaatctttt tgttcattgg ttggatgagc gtcttttatt tacaagaact tagacaattt
    15541 gatatttcta aggtatcatt ttccactagt gaaattggct ggtctatgaa ggatgtaatc
    15601 tgcttgctag gaagtctcgc tctttcagga agcatgatgt tactttatat acactttttt
    15661 caggatcatt ggcgaagtct ttggcatcga caaaagttag ctcggatgat tctagaaaac
    15721 cattggtatg aagtaaagca gactcaaggt gaaggttttt tcaaagattt gaatagtagt
    15781 tggaccaaag agagtatcag ttacttcccc aaaatttatt atcgaatgaa agatggctta
    15841 ctttctattc gcgttcaaat ttcactggga aaatatcagg atcagctatt gaagttggaa
    15901 aataagttag aaagcggact gtattgtgag ttagtagaaa aagaactcaa agactcctat
    15961 gtggaataca ccttgttata cgatatgatt gccaatcgaa ttgggataga agaaatagtg
    16021 gcagaaaatg gggcgttgcg attgatgaaa aatcaagtat gggcgtatga ttccttgccg
    16081 catatgttaa ttgctggcgg cacaggtggt gggaagacct atttcttact caccattatt
    16141 caagcactat tgaagtcaga tgcagaattg tttatcctcg atcccaaaaa tgcggacctc
    16201 gccgatttag gtacgataat gcctcacgta tactcccaaa aagaagaaat ttctgaatgt
    16261 gtggaagatt tttacgaacg catgatagct cgtagtaggt caatgaaaga aatgcccaac
    16321 tacaaaacag gagagaatta tgcgtatctc ggacttccgc ccaacttttt aatctttgat
    16381 gaatacgtgg cttatatggg tgcgaatcgt tttcctacaa gcatcgaata gatgtgaaat
    16441 ggaagcctat tgagattatc aatagtgaca actaatgttt tgagagatgg aatgaaagcc
    16501 ttcaagttga gctgaaacat ccccgctaat actcctacat gctctaatca atgaagtaga
    16561 ttggttttgg tatgaagcta ggtgaagtcg tctgaaatct gcctaagtgc ttgagcataa
    16621 ggctgactat agggcgggcg gctgaaaaag ataactatgg taagaatgtc tgaaaatgac
    16681 tgacgaatct gcgaatgtac gggtctaaaa ggctgatctt attgaaagat aggaacatac
    16741 ggacgtatgg tgagataccg acaagtaagg ttccatgata tgaaaatcgg gatagctaac
    16801 gaagaagcta taatttcaca ggctcatagt agatacctaa ggttatacat gatagctaaa
    16861 aacattggaa cgatgtaagc agaaaactat caattaaatg actacttcta gataggtgca
    16921 tataagtaat aacgaaattg ctttgtttct gtgaaagtaa gggcacagta ccgatgaagc
    16981 gtctaacaaa tgtggaggga tagccctaag tctatttaat aacaatgaat gttgaaacag
    17041 atgaagttca aggatctggt aagaacgtgg gaaaatccgt tatggaggtg ccacgcttga
    17101 acacaaaaat acgttactgg gaatattatg atctacaaga aacattcgat cagctattta
    17161 ctcaaagtag aaacgggaaa aagttttatc aattatatga gttaatcatt tctgaaaata
    17221 atattctttt agcataccgt actatcaagg caaacaaggg gtcttcgaca ccaggaacgg
    17281 attccttcac aattgataac tataaggaaa tgaaccaagc agagtttatc catcttattc
    17341 tcagtcattt agaaaattac aaaccaaaat ccataaagcg agtaatgata cctaaaccca
    17401 atggtgagaa acgcccatta ggaattccat gcatgattga tcgaatgatc caacagatgt
    17461 tcaagcagat actggagcca atatgtgaag ctaagtttta tgaacatagc tacggtttca
    17521 gaccattgag aagtgcaaag catgctctag gtcgcattat gtatctcata aacatcagta
    17581 aaatgcacta tgcagtagac attgatatca aaggtttctt tgataatgta aaccaccgtt
    17641 tactgataaa acaattatgg aatataggaa tttgtgacaa acaagtctta gctattcttt
    17701 caaaatctct gaaatcaccc attcaaggag aaggtatccc gagcaaagga acgatccaag
    17761 gaggtatcat ttctccacta ttatctaatg ttgttctaaa cgacttagac cattgggtct
    17821 caaagcagtg gcataccttt gaaacaaagt atccctatac taaaggttac aataaatttc
    17881 gtgctctaag agatacaaat ctaaagcaag gctatattgt caggtacgca gatgacttta
    17941 aaatcatgac taatgattat ccgacagcat taaaatggtt ccacgctgtc aagctttacc
    18001 taaaagacag acttaaatta gatatttcca atgagaagtc taaaatcgtc aatttgcgta
    18061 aatgtaagtc ggaattttta ggattcgcta tttgcgtgaa acaaaaaggg aaaaaatggg
    18121 tttgtaattc acgtatttct aacaaaaaaa aggatcagat taaagaagag attaaacaaa
    18181 gaatcaaaga tattcaaaag agtcctacag cacaaaatgc tctcctgttt aatgctctcg
    18241 tgctcggtgt tcataattat ttcaggtatg ccactcatat taatttagat ttgaatagga
    18301 tgaactacgt tctttcattc actacttaca accgattatc aaattgtagt acaagatgtt
    18361 accccaacaa agcttcccca acttacaaaa agttttactc aacaacgatg aaaacgtata
    18421 aagtagctgg agtctatttg taccctcttt gcgacgtatc tacaaaaaca atttacggat
    18481 ttaatacgga ggatacaccg tttactccgt ttggtcgtca aagattggag cacaaaagcc
    18541 tacagtctct tgtgttccaa gaattaagaa aattgatgga atcgaaaata ccgaatagaa
    18601 cggttgagta tttagatagt agaatatctc gttactcaat gaaatcaggc aagtgtgaga
    18661 ttacaaaaca atttttgcca gcaaaagccg ttcactgtca tcactatttg ccaaaaagtc
    18721 ttggtggaga cgacaaattc gataacttga gaattattca taaggatatc catcttctga
    18781 tccatacaac aaataaaatg ataatcgatc actacgtgca tgaactgaaa ctggtgccag
    18841 agcaaatagc aaaaatcaac ctttatcgaa agatgtgtaa tctgcaaaac attcaataga
    18901 aaataaatag atggaacgcc gtatgaggtg aaagtctcac gtacggtgtg gagcggggga
    18961 aaagatggag attatatcaa attcttacct atcgctatag atgttaacga caaaagaaag
    19021 tgcggtgatt ttgaataagc ttaaacaaat cgtgatgtta ggccgtcaat ctggtttctt
    19081 tctgattcta gcttgtcaaa ggccggatgc gaaatatcta ggagatggga ttcgcgatca
    19141 gtttaacttc cgtgtggctt tgggtcgtat gagtgagctt gggtattcca tgatgtttgg
    19201 agaagtcgat aaaaattttt ttatgaaacg catcaaagga cgaggttatg tagatacagg
    19261 gggcagtgtg attagtgagt tttatacgcc acttgtacca aaagggtatg atttcttaag
    19321 ggaaattagc aacattgttg gattaaccgt tcatacggaa agagaaaata atagtgtgta
    19381 gcctaggaat atcaataatc ctgggctttt ttattgaggt gatttatgac atttttagat
    19441 ttattcgccg ggattggtgg ctttcgctta ggtatggaac aagccggtca ccagtgtatc
    19501 ggtttttgtg aaattgatga atttgctcgg aggagttata aagcaatcca tgatacaagg
    19561 aaggaggtgg aaatgcatga catcacaagt gtatcagacg aatttgttcg atccctcgga
    19621 ccagtggaca tcctttgcgg cggctttccg tgccaagctt tttcaattgc gggaaagcgg
    19681 caaggatttt ccgatactcg aggtacttta ttctttgaaa tcgctcggtt cgccactctt
    19741 ctccaaccta agtttctatt ccttgagaac gtccggggat tgctcaatca cgaaggaggg
    19801 gctacgttcg agacgatcct ccgaacgttg gatggattgg ggtatgatgt ggaatggcaa
    19861 gtgcttaact caaaggccta cgttccccaa agccgtgagc ggatcttcct tatcggacat
    19921 tctcgagatg catgtaccga acaagtattt cctatcattg gatcgtcttc aacatctgat
    19981 caaaacatca gaaacttggt aaatatcaac ccttccaatc gaggaatggg gggacaagtc
    20041 tatgggtcag atgacgtagc gcctaccttg accggtgatg aaggaatcaa aatcgcattg
    20101 ccggtaaa
//
LOCUS       DADQDV010000056        19999 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.057, whole genome shotgun sequence.
ACCESSION   DADQDV010000056 DADQDV010000000
VERSION     DADQDV010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 19999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19999
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.057"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..1835)
                     /locus_tag="J8S10_002088"
     CDS             complement(<1..1835)
                     /locus_tag="J8S10_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630668.1"
                     /translation="MTQEFIYAYKKMPDDLSVNGASLVDWEDLPEINRVLNGQYRFYG
                     NYSRSGQYRSYLKKGNFIKAKVPDGSWQYFEIYNVKKNLTSVSVTARHIGFMANKNFI
                     VKSFTDNGNGSQIMTNLKNSLAFDQKFNYLSNVGTTHQFTARQVAPVEAIIGSNNGNQ
                     NLTGVTSAELDMDNYDLKLVKQIGSDNGFRIDFGINLEAIEEEIDEESIVNSLYLVGG
                     VPDNDYDEDKEPIEYGYLEIDGVTNENRRIAKRENGDCKTVDELIKWGKTLFDNDRIH
                     EPKATHTVSMVALEHTLEYGDMYQELASLHFGDVAHVRAKELDIEIKERMVEYTYFPT
                     LGKYKDIVLGNDLSLYTSAVNTQAQELKKKIDNRTETLVQNVLNATAWITGNSGGHVV
                     FRPEKAPSEILIMDTPNVANAKRVWRWNLNGLGYSDNGVNGPFGIAITSKGEIVADFI
                     KVGTINAEVFETSFNAYGDVLKLVKGTLQIWNENKKIMELTKKGMEFWNRKESIGTIG
                     TTDSAGNPFPNAVTPTPLEENSLVIRTNGDGKYILISPTAEKGFVLLGNGKAYYFGDL
                     DIQGKLTVRGKEVIPGQNGGPSGGGETPGGYPDELKTDAEKRAWR"
     gene            complement(1832..2536)
                     /locus_tag="J8S10_002089"
     CDS             complement(1832..2536)
                     /locus_tag="J8S10_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAZ9630669.1"
                     /translation="MNPDEPNFIWKNRNAVIDMNCIIEAELPDIMPNKRYETYTIQGR
                     SGELTETFDDYEPFDLEIEGITIPHSKLREVKRWLTGKSQLITHNDPDKYLEAICSMD
                     KEVPFENEWGFFYTFDVTFRCQPLKRKIGEAPKIFHSSVMDIFDHGDEIAHPYLEIES
                     NGGDITIAVGDKSLTILNTLAATIVVDTQLGKAIQEGLNLFTRGDWPVLQPEWNQVKI
                     SGKFKEVRFWNRSVYL"
     gene            complement(2548..4857)
                     /locus_tag="J8S10_002090"
     CDS             complement(2548..4857)
                     /locus_tag="J8S10_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HAZ9630670.1"
                     /translation="MAGKESDVVLNFKTNGEVSYSKTIKEINKEMNLAAAEYKNQVSA
                     MDKDATQTEKLRAAKQKLEKQLGLAEQRSQMLREEYEKSVKETGEYSAESEKLYKQLL
                     NSETGENKLRTALEQTNDALKEQGDVSVDTAKKLQKIEETGEKVKGVGEKMSVGVTAP
                     IVAAGAAGLAAFGEVDEALDTIITKTGATGDQADRLSQSFKNVGSNTHLPLQTVGEAI
                     GEVNTQFGFMDKKLEDSTNYLLQYAEINDTDVSQSAISARQAIDAYGLEYDDLNSVLD
                     VTTKTSQNTGQSVDDLMQKAIDGAPQIKQLGLSFGEGVTLLGQFEQSGVDSSAALSSL
                     SKATVAYAKDGKSLSQGLEELQDKVKNAGSETEAINAAAEVFGTKGGPRMADAIRRGT
                     LNLEDLAKTAGESGGAVGDTFDATLDPIDQADQAMNNAKLAMADVGEAVQVSLLPFFE
                     KATSLLQEFSKWWGSLDQDTKNWIITIAGIAAAVGPVLIVLGSLMGSVTKIVGEVKSF
                     IGVWQGLAGLFGMSGGWFALAVIAIGALVTGLIWAYNNVKWFHDGVNSFFKGVSDVAV
                     EIFNFLSGYFGGFFDGVIANFNNFYNAGKRIFSGFLDFITGVFTGNWSKAWQGLVDIF
                     GGIFDGIVAVGKAPINAMIGLINGFIGGLNNIKIPKWVPGVGGKSFSISKLPYLAQGG
                     HLINGQAIVGEAGPELLTAKNGKTTVTPLSDEEKRKGISGRVSGGSIEQHIHIGKVDA
                     NNPSELDRMNRKFAKANKQAIRDLGGVPI"
     gene            complement(5052..5516)
                     /locus_tag="J8S10_002091"
     CDS             complement(5052..5516)
                     /locus_tag="J8S10_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630671.1"
                     /translation="MARLSDYGIHVEDLKNSAVVIIQGAEFPISFTMQTMEFIADVYG
                     GDYSQFESDMNAMLSKKEGQISSANLSPSDLKIMRALIYAMLRTGGLEEDPETIFKFL
                     GMSGEVLSAYSTCMEIFASQTFQVEDLKKSKKPQDFQKAQAKRKKNKKNRKR"
     gene            complement(5516..6142)
                     /locus_tag="J8S10_002092"
     CDS             complement(5516..6142)
                     /locus_tag="J8S10_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAZ9630672.1"
                     /translation="MGKQDTFYFEGLDDILIAMMATPDSVGTAPTYSEVLRLPIATKI
                     GVKGNGTALEKWASSKMFRRVSRETKHELALDHVGIPIEVMDEIKGLVAKSGVTFSKN
                     TAREFPYFAFGFIGNIENGGKKAVWYPNTQLSNVIDEEYATAEEETKIDDVTANLVSI
                     GLKYNNVMYASFDSNRDGASLELFNKFIAQPVYDEEQWKTLAKVGGAG"
     gene            complement(6149..6514)
                     /locus_tag="J8S10_002093"
     CDS             complement(6149..6514)
                     /locus_tag="J8S10_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HAZ9630673.1"
                     /translation="MPSNKNGFSEISDYLGNLSKVDPKKLSLESLEEAANFYLKQLLP
                     NIPKSLLKKKHMRDQIKVVVENDQVKVQFEETAFYWRFAENGTTNQRAQHFASGTYEQ
                     NKEKIEEIMTRKILDLWEG"
     gene            complement(6504..6842)
                     /locus_tag="J8S10_002094"
     CDS             complement(6504..6842)
                     /locus_tag="J8S10_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630674.1"
                     /translation="MSISFDELKTALKSTKLAVFRDKARLGTMYPYIVYSNVSNSKKM
                     ASGKVYKKLPYYQVSFFTLGTEQDLVVIEQALQNAGIPYSDFTGIQGDENDDTVTNYY
                     TYVRCVENAK"
     gene            complement(6832..7158)
                     /locus_tag="J8S10_002095"
     CDS             complement(6832..7158)
                     /locus_tag="J8S10_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HAZ9630675.1"
                     /translation="MPKRQTNNLRWKAELLDIKTGTDGNDRPTTIYEFKRLIFYEELG
                     VTSQEKYLSQQAKTDVVRRIKVRWDKSITEKLSALKIDSVTYNITRIYTNPDAREMEL
                     SLAYVD"
     gene            complement(7139..7417)
                     /locus_tag="J8S10_002096"
     CDS             complement(7139..7417)
                     /locus_tag="J8S10_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HAZ9630676.1"
                     /translation="MEEQTKELSLEEKFKSHIHFEEGMDDSLLSFYLNMAKDYVKTAT
                     GGQQEYLILMVAGIAYEYRVSEDELDKAMNAMTPFIVQGAIQNAEETD"
     gene            complement(7419..8783)
                     /locus_tag="J8S10_002097"
     CDS             complement(7419..8783)
                     /locus_tag="J8S10_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HAZ9630677.1"
                     /translation="MDKELLKKMKARREQRLTELREKVESGELREADLEAVKEEIDSV
                     IDELNGIKDELGADSGTDETDDNTDDQSNSTDSDESRSGEDNDQEEDSDSEDSSENRS
                     GMITQQQRDGLLGSIKNGLEARAKMTKKQKDQQLRKAFANFVAGNISEAEARALGIEA
                     GNGSVTVPEVIASEVITYAQEENLLRKYGTVVRTSGDVKYPILVKKADANVNKKERST
                     DIAETAIQFDEILLNPAEFDALATVTKKLLKMSGVPVEDIVVEELKKAYVRKEINYMF
                     NGDDAGNENPGALAKKAVAFKKPLDLTASGAGQKLYDALIEFKNTPVTEVMKKGRFII
                     NRAALTAIEKMKTDDGFPLLRPFTQAEGGIGYQLVGYPVDWTDAADKKGEPDTPVLYF
                     GDFSAFKIQEVIGALEIQKLVEKFSGKNQIGFQIYNLLDGQLVYSPFEPAVYRYEITK
                     PVGG"
     gene            complement(8796..9371)
                     /locus_tag="J8S10_002098"
     CDS             complement(8796..9371)
                     /locus_tag="J8S10_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HAZ9630678.1"
                     /translation="MEMKKKEIRTIDITNLSTRSDEETHTRTISGYAAVFNSQTLLWD
                     DLSEVIVPGAFSKAISNSDVRCLFNHDWSNVLGRTKSGTLRLEEDERGLKFEVDLPDT
                     TVARDLVKSMERGDINQCSFGFVPTEETWDYNSEPMLRTIHEVELYEVSIVPLPAYED
                     TEAALRSRDELEKNVEERKKLIKKINQALEA"
     gene            complement(9337..10524)
                     /locus_tag="J8S10_002099"
     CDS             complement(9337..10524)
                     /locus_tag="J8S10_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAZ9630679.1"
                     /translation="MEKRGYIEDIFGHYTRYGQRYVTDSSIMESSDVYELVQDISNQV
                     ALATPIVIGPDGNEVKDHHLLNILKSPNDYLTGFEFTKLETNTLLINGETFPLTDRDQ
                     LHLAYGVTTKINERLQEEFEMNGQKIPGQMIRHIKNIGTDSLKGAGIIDLARNTLEGV
                     LSAEKVLTDKYTKGGLLAFMLKLDAHINPNNSAQTKIVKAILDQLEGTQNESDHSVKM
                     IPLGKGYSIETLKSPVDDAAILNYLGVYKKDLGKFLGINVDTYQSLMKTDIEKAMMYL
                     HNKAIKPILKNKSEHYTALFFMPNSGYRVEWKINILDFVPYSTKTNIGYNIVRTGITS
                     PDNVAEMLGFPKQNTPETQAIYISNDLSRIGQKNATDDSLPTNDQDLKGGDGNEEEGN
                     SHD"
     gene            complement(10588..12315)
                     /locus_tag="J8S10_002100"
     CDS             complement(10588..12315)
                     /locus_tag="J8S10_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HAZ9630680.1"
                     /translation="MIEPGVNYADLFAKEVRKKPKKYPKTVRLAIDRWYQWKKRKDIW
                     FDVDRANEMMDWVESFIVHTKGEMVGKPFLLEPWEKFIYSWIYGWVKENEKGQIVRVT
                     REAYVQIPKKNGKTLIAVGSLGYAMYGEGALSVDCYACASDFAQAQYAAKPFAVTILN
                     NPILLEGTKIFRGPKGTVSSITYDYIHEDMAYSNKFIVQTKNIDNIEGSNPYFVLNDE
                     LHKQEKMEQYDNFKSAQISLPQPLMFNISTAGKGSSSVGMRVYREAKEVLKRDDNDSN
                     FVLIYEPNKNYDWTDRKVWEMCNPNWGISVDLSALESAFKTAQRSAHSKAEFLTKHLD
                     VFVNGADNFFEQDQVEPCLVTTQELGDLSGEPCYIGLDLSRTRDLTCVSLNFPTWDED
                     GKAVLKVKQLYFIPNEDLEFREKEDNVPYSDLAEQGFVEFCDGKMIDQDQILQYIEDC
                     MNLYDIQQVNYDPAMSDKLVEKLENLGLECVEVAQYPKVLNAPFDDVERLFYEKRIQF
                     DNPLFLYCTLNVVAITNINGQKAPSKRQSKKKIDGFVAFLCGHKETMNQMTDIDSDEL
                     DDYLSSIYR"
     gene            complement(12312..12764)
                     /locus_tag="J8S10_002101"
     CDS             complement(12312..12764)
                     /locus_tag="J8S10_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HAZ9630681.1"
                     /translation="MTTKAQRKAIIDEKVSAEKARILEIMNLSDLYTITLDPLIESYL
                     DIFEIYQHKYLLWKEKGFPETQKFTNKSGATNQSKHPLAQQVETWADKKMKALDLLGL
                     TNKAKTGRLIAGGSTARKDEEITRPEVKPVDELAAHRNKWRKKAGAEK"
     gene            complement(12876..13256)
                     /locus_tag="J8S10_002102"
     CDS             complement(12876..13256)
                     /locus_tag="J8S10_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HAZ9630682.1"
                     /translation="MKYCQFDGCTNKIAKGIYCTEHKRSSRSRKKKQQAKSVYHHENK
                     PFYRTQAWKDMRQFIYEREGGHCQRCGQFIFGKRAHVHHIVPIKDNELLKLDPNNLML
                     LCSKCHPIVENETEDKKVFPSYFN"
     gene            complement(13253..13639)
                     /locus_tag="J8S10_002103"
     CDS             complement(13253..13639)
                     /locus_tag="J8S10_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630683.1"
                     /translation="MAMIKIRTSISGTEYWDSEKKRTVVVPKDQEPNFEVKEEKGILS
                     DGKSFVAVNGELIAHSSEILDSDGNTAANFDGDEATNDQSTEDTDELDNMTAKELRAY
                     AKKHGIDIPGAIRAKGDIINLIREVE"
     gene            complement(13641..13919)
                     /locus_tag="J8S10_002104"
     CDS             complement(13641..13919)
                     /locus_tag="J8S10_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630684.1"
                     /translation="MNDFHEAVLSIEVESSLAKVYKKAIEAENSPYRENWNGNHAHVQ
                     VENDDYRTGMNTLVISLLSHTLPNLQETIEWYERMGAKVIRTNYKGEN"
     gene            13967..14695
                     /locus_tag="J8S10_002105"
     CDS             13967..14695
                     /locus_tag="J8S10_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HAZ9630685.1"
                     /translation="MRGVLMLQEVNIKYRDRQNTETIYLPNSCPHCGNIMTPYVYFGV
                     SSYSAFDNDRIFGVLVQCINDECNKFYSLQFINTFNEDEGYSENILIKDYYRPPIKID
                     LPENIEKVSPTFVDIYTQATQAKSEQLEQIAGVGYRKALEFLIKDYAISKNSEDEDKI
                     KKMLLGKTIENYLNDFPKLQRLAKAATWIGNDETHYVRRHTNKDVHDMDAFIKSAAQF
                     IAADYDADLADQFINGNNFMPTTN"
     gene            complement(14841..15317)
                     /locus_tag="J8S10_002106"
     CDS             complement(14841..15317)
                     /locus_tag="J8S10_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HAZ9630686.1"
                     /translation="MRFHWLKDYQELDEQILYLKWNLNKSKLELNRWVCGDLANVRIE
                     KNSRTSSLEENIQKIENELELLIEQKEEMLLLIDSFSGIDNQIVKMKYVDQMSLEDIA
                     ESVGYSSSYVRQRHAEIRKTLNFLDEYEHRQADRLKKENEIDFYNSEKYKEQLSLF"
     gene            complement(15277..15624)
                     /locus_tag="J8S10_002107"
     CDS             complement(15277..15624)
                     /locus_tag="J8S10_002107"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630687.1"
                     /translation="MNVIDLPVHFRGTNYFYASNLIQKKMSKDERKILANFYLVLKIE
                     QNVFSERRIVWEKQNQRLRRKNDVWNKRQSRMERLRKNKKATPFEIAAQYYSTIRGGV
                     CEISLVKRLPRTR"
     gene            complement(15611..15796)
                     /locus_tag="J8S10_002108"
     CDS             complement(15611..15796)
                     /locus_tag="J8S10_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630688.1"
                     /translation="MKVYILAITEGTWMFPVGSGKIYKSKTAAYKAFEKYKKENGGGT
                     NAKILVADNWHEEGERN"
     gene            complement(15797..16069)
                     /locus_tag="J8S10_002109"
     CDS             complement(15797..16069)
                     /locus_tag="J8S10_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3850 domain-containing protein"
                     /protein_id="HAZ9630689.1"
                     /translation="MIHELKILPEYFEAVTSGRKQFEIRKNDRDFKVGDQLILREYKK
                     YIKHELPGLTRPTFSYTGDSYKAEITYITDYMQKSGYVVLGIKGVN"
     gene            complement(16066..16269)
                     /locus_tag="J8S10_002110"
     CDS             complement(16066..16269)
                     /locus_tag="J8S10_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630690.1"
                     /translation="MVKVREQFKIVSDEGNVYKIKIVNINEYREADHKYLVDLYMNDK
                     YLGEGFCGDSLFDDERILKEETE"
     gene            16394..16606
                     /locus_tag="J8S10_002111"
     CDS             16394..16606
                     /locus_tag="J8S10_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630691.1"
                     /translation="MNINNLVKLVEQRFKESGLEQLKKDNSPELFSNFTEDDIPTLKQ
                     LKYYSDYWTQTRENELNLEKLIIKKK"
     gene            complement(16639..16833)
                     /locus_tag="J8S10_002112"
     CDS             complement(16639..16833)
                     /locus_tag="J8S10_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630692.1"
                     /translation="MMIQLAGIQTGKIYFSGESKSEANQWLLKTYTNNKKLRKKYPDL
                     LLKDDQIMPEPMILTRKEGS"
     gene            complement(16846..17028)
                     /locus_tag="J8S10_002113"
     CDS             complement(16846..17028)
                     /locus_tag="J8S10_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630693.1"
                     /translation="MRATDPVIILEEAKFIWTHEEIEQARLLFSQGVKPSKVAEIMGQ
                     KILDVGLLLLHLAEKI"
     gene            complement(17655..18020)
                     /locus_tag="J8S10_002114"
     CDS             complement(17655..18020)
                     /locus_tag="J8S10_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630694.1"
                     /translation="MIDAKQVQKQKDGMLMFEAYVLPFLNQFEVLECSASGEELEYVV
                     IRETKENVQKLNEFLCTINCWDMIAPGFLCPAMGEFLEYCRLEDAGTLDLAYLVYNYL
                     NINTDHLWFGTAERKWVVR"
     gene            complement(18060..18362)
                     /locus_tag="J8S10_002115"
     CDS             complement(18060..18362)
                     /locus_tag="J8S10_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630695.1"
                     /translation="MDELIAKVEQWAKDKGLDQADFSKQMLKTVEEIGEVAASLARKD
                     EHGLRDGIGDVVVTLIILAMQNDMDLYECLDFAYDEIKGRTGKMVNGVFVKSSDLK"
     gene            complement(18362..18661)
                     /locus_tag="J8S10_002116"
     CDS             complement(18362..18661)
                     /locus_tag="J8S10_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630696.1"
                     /translation="MDKKAAMQRIIELTYSEDWQEDKKIVAEVQKLGKSMWTEKPKRR
                     TPRKIAIWHGDRILVTGTAKQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
     gene            complement(18824..19093)
                     /locus_tag="J8S10_002117"
     CDS             complement(18824..19093)
                     /locus_tag="J8S10_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630697.1"
                     /translation="MKIDYLELINEIANYKKGEELDVLRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDGTQLRNLAYTKLLFIDCVKGLQKHLNELEQV"
     gene            complement(19105..19854)
                     /locus_tag="J8S10_002118"
     CDS             complement(19105..19854)
                     /locus_tag="J8S10_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAZ9630698.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIRELPPSKKSKAKPVRHKYGEYKNVLLSDEQME
                     KLKTEFPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKEKSEPKNASSGYKRTGR
                     REKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            complement(19851..>19999)
                     /locus_tag="J8S10_002119"
     CDS             complement(19851..>19999)
                     /locus_tag="J8S10_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630699.1"
                     /translation="EYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQKTIKKLNI
                     GGEK"
BASE COUNT         5547 a         4235 c         3101 g         7116 t
ORIGIN      
        1 attctccaag ctctcttttc tgcatctgtt tttaattcat caggataccc accaggtgtt
       61 tctcctccgc cagatggacc gccattttgt cctggtatca cttctttacc tctaacagta
      121 agttttccct gaatatctaa atcaccgaaa taatatgctt ttccgtttcc taataacaca
      181 aatccttttt ctgcagttgg agaaattaaa atgtattttc catcgccatt tgtacgtatt
      241 accaaagaat tttcctcaag aggtgtaggt gttacagcat ttggaaatgg atttcctgct
      301 gaatctgttg ttccgatcgt tccaatggat tcttttctat tccagaattc catacctttt
      361 ttggttagct ccatgatttt tttgttttca ttccaaattt gaagcgtgcc ttttacaagt
      421 tttaacacat caccataagc attaaaggaa gtttcgaata cttctgcatt tattgttcct
      481 actttgatga agtcagcaac aatttctcct tttgatgtga tagcaatacc gaacgggcca
      541 tttactccgt tgtctgaata acctaagcca tttaaattcc aacgccacac tcgctttgca
      601 ttcgccacat ttggagtatc catgataaga atctctgatg gagctttttc tggacgaaaa
      661 acgacatgcc caccagaatt accagtgatc catgccgtcg cattcaacac attttgaact
      721 aacgtttctg ttcgattgtc gattttcttt ttcaattctt gtgcttgagt atttactgcc
      781 gaagtgtaca gtgataaatc attacctaaa acaatatcct tatatttccc aagcgttggg
      841 aaataagtgt attcgaccat acgctctttt atctcgatat ctagctcttt cgccctaaca
      901 tgagcgacat caccaaagtg taaagacgct agctcttgat acatgtcacc gtattcgagt
      961 gtgtgttcca acgccaccat actgactgta tgagtagctt ttggctcatg gatacgatca
     1021 ttgtcaaata aggttttgcc ccatttgatc aattcatcaa ctgttttaca atctccgttt
     1081 tcacgtttgg caatacgtcg attctcgttg gttactccat caatttctaa ataaccatat
     1141 tcgataggtt ctttgtcttc atcataatcg ttatcaggaa caccgccaac caaatacaaa
     1201 ctattgacaa ttgattcttc atcaatttct tcttcgattg cttctaaatt gatgccaaaa
     1261 tcaatccgaa aaccattatc tgatccaatc tgttttacca gtttcaaatc atagttatcc
     1321 atatcaagtt ccgcgctagt cacgccagtc aaattttgat taccgttatt tgaaccaatg
     1381 attgcttcaa ctggcgcgac ttgtcttgct gtaaattggt gcgttgtccc tacattcgaa
     1441 agatagttaa atttttgatc aaatgccaaa ctgtttttaa gattggtcat gatctgagac
     1501 ccattgccgt tatccgtaaa cgacttgaca ataaagttct tattggccat aaaaccaata
     1561 tgccgagctg ttacagaaac ggaggtcaaa ttctttttga cattataaat ttcaaaatat
     1621 tgccatgatc catctggtac cttcgctttt ataaaatttc ctttttttaa ataagagcga
     1681 tactgtccgc ttcttgaata gttaccataa aaacgatatt ggccattcag cacacgattg
     1741 atttctggca aatcttccca atcaactaac gacgctccgt tcacgctcaa atcatctggc
     1801 atttttttat aagcataaat aaattcttgc gtcacagata cacactccta ttccaaaacc
     1861 gcacttcttt aaattttccg gatattttta cctgattcca ttcaggctgc aatactggcc
     1921 aatcaccacg cgtaaataaa ttcaaacctt cttgtattgc ttttccaagc tgagtatcaa
     1981 ccacgattgt tgcagctaac gtattaagta ttgttaggct tttatcaccg acagcgatcg
     2041 ttatatctcc tccgttcgat tctatttcca gatagggatg tgcaatttcg tcaccatgat
     2101 caaaaatatc cataacacta gaatgaaaaa ttttaggtgc ttcaccgatt tttcttttga
     2161 gtggctgaca acgaaaagta acatcgaatg tataaaagaa gccccactcg ttttcgaaag
     2221 ggacttcttt atccatgctg cagatagcct ctagatactt gtctggatca ttatgtgtga
     2281 ttaattggct tttaccagtg agccatcgtt tgacttctct cagtttcgaa tgtggaatag
     2341 tgatcccttc tatttccaaa tcaaaaggtt catagtcatc aaacgtctcc gtcaattctc
     2401 cgcttcggcc ctgaatcgtg taagtttcgt atcgcttgtt cggcataata tctggaagct
     2461 ctgcctcaat gatgcaattc atatcaatta ctgcattccg atttttccaa ataaaatttg
     2521 gttcatctgg attcataaat tgtcgactca aataggaaca cctcccaaat cacgaatagc
     2581 ctgtttgttt gctttagcaa atttacgatt catacgatct aactcagatg gattgtttgc
     2641 atcgactttg ccaatgtgta tatgctgttc aatgctacct ccagaaactc ttccactgat
     2701 ccctttgcgt ttttcttcgt ctgataatgg agtaactgtg gttttaccat tcttggcagt
     2761 cagtaactca ggtccagctt caccaacaat cgcttgtcca ttgattagat gaccgccttg
     2821 tgctaaataa ggcagttttg aaatagaaaa tgattttcca cctacaccag gaacccattt
     2881 tggtatcttt atattattca atccaccaat aaatccattg atcaatccaa tcatggcatt
     2941 aataggagct ttccctacag caacaatacc atcgaaaata cctccaaaaa tatcaactag
     3001 accttgccat gcttttgacc aattccctgt aaatactcca gtgataaaat ctagaaaacc
     3061 actgaaaatt cgttttccag cattataaaa attattgaaa tttgctataa caccatcgaa
     3121 aaatccacca aaataaccac ttaaaaaatt aaatatttca acagctacat ctgaaacacc
     3181 tttgaagaaa gaattcactc catcatgaaa ccatttaacg ttattatatg cccaaattag
     3241 tccagtaact aatgcgccaa tagctataac tgctaatgca aaccagcctc ccgacattcc
     3301 aaataaacca gcaagtcctt gccaaactcc tataaaactt ttaacttccc caacgatttt
     3361 tgtaacagat cccataagtg aaccaagaac gattagtact ggtccaactg ctgccgctat
     3421 accagcaatt gttatgatcc aattctttgt atcttgatct agagaccccc accatttaga
     3481 gaattcctgt aataaggaag ttgctttttc aaaaaaaggc aaaaggctta cttggactgc
     3541 ttcacctacg tcagccattg ctaattttgc attgttcata gcttgatcgg cttgatcaat
     3601 tgggtcgaga gtagcatcga atgtgtctcc tacagctccc ccactttctc cagcagtttt
     3661 tgctaaatct tccaggttca aagtacctct acgaattgca tcggccattc taggaccgcc
     3721 tttagtcccg aatacttctg ctgctgcatt gatggcttct gtttcagaac ctgcattttt
     3781 taccttgtct tgtagttctt ctagtccttg acttaaagat tttccgtctt tcgcataagc
     3841 cactgttgct ttagataaac tacttaaagc tgcgcttgaa tcaacaccag attgctcaaa
     3901 ttgtccaagt aaagtgaccc cttcaccaaa gctcaaccct aattgtttaa tttgtggtgc
     3961 gccatcaatt gctttttgca tcaagtcgtc tacagattga ccagtattct gcgatgtttt
     4021 cgttgttaca tcaaggacag aattcaaatc atcatattct agtccataag catcaatagc
     4081 ttgtcgagca gatattgctg attgcgaaac atctgtatca ttgatttcag cgtactgtag
     4141 gagataattg gttgaatctt ccagtttttt atccatgaat ccaaattgtg tatttacctc
     4201 accaatagct tccccaaccg tttgtaaagg taaatgagta tttgaaccaa cgtttttgaa
     4261 agactgtgaa agtctatcag cttgatcacc tgttgctccg gtttttgtaa tgatggtatc
     4321 aagtgcctcg tcaacttcac caaatgctgc aagtcctgct gctcctgccg ctacaatagg
     4381 cgcggttact ccaacagaca ttttttcacc aacgcctttt actttctcac ctgtttcttc
     4441 gattttctgg agtttttttg ctgtatcaac agaaacgtca ccttgttctt taagtgcatc
     4501 gttcgtctgt tctaatgctg tacgaagttt attttctccg gtttcagaat tgagtaattg
     4561 tttataaagt ttttctgatt cagcagaata ttcaccggtt tctttgacag atttttcata
     4621 ttcctctctc agcatttgag atcgttgttc agccaatcct aattgttttt ctaatttttg
     4681 tttagccgct cgcaattttt ctgtttgagt tgcatccttg tccatcgcag acacttggtt
     4741 tttgtactcg gcagcggcta agttcatttc tttgttgatt tctttgattg ttttcgaata
     4801 actgacttcg ccattcgttt taaaattaag aacgacatca gattctttac cagccattta
     4861 tcttagcgct cctttctacc accaaggcga tttatccata gttacagatt gaggtggttc
     4921 aaaatcggtg ttttgttgta accactgtaa ataagatttg agccacaagt taggtgtaga
     4981 ctttaaaaag aaactctcac tccaattcaa tagagtgaga gcaacgtaaa tataaaaact
     5041 ccaaggagtt cctatctctt ccgattcttt ttgtttttct ttctttttgc ttgcgctttt
     5101 tgaaagtctt gtggcttctt ggattttttt aggtcttcca cctgaaatgt ctggctagca
     5161 aaaatttcca tacaggtact ataagcagac aacacctctc cactcattcc caaaaatttg
     5221 aaaatagttt ctggatcttc ctctaaacca ccagtacgca gcatggcata aatcaaggca
     5281 cgcatgattt ttagatcact aggcgataag ttagcagaag aaatttgtcc ttctttttta
     5341 gatagcatgg cgttcatatc agattcaaat tgcgaataat ctccaccata cacatctgct
     5401 ataaattcca tcgtttgcat agtaaatgaa atagggaatt ctgcgccttg aataattaca
     5461 acagcagaat tttttaagtc ttcaacgtga attccataat cagataaccg agccattaac
     5521 ccgcacctcc aactttagcc aatgttttcc actgttcttc atcgtataca ggttgagcaa
     5581 tgaatttatt aaataattct agagaagctc cgtctctatt tgaatcaaaa cttgcataca
     5641 tcacattatt gtatttcagt ccgatggaaa ccagatttgc agttacatcg tcaatttttg
     5701 tttcttcctc tgcagtggca tactcttcgt caatcacatt ggatagttgt gtattaggat
     5761 accaaactgc ttttttaccg ccattttcaa tatttccaat aaatccaaag gcgaagtacg
     5821 gaaattctcg tgcggtattt ttgctaaacg ttactccgct tttagcaact aatcctttga
     5881 tttcatccat cacttctatc ggaataccca cgtgatccaa cgcaagttca tgttttgttt
     5941 ctcgcgacac acgacgaaac attttgctgg atgcccattt ttctaatgct gttccattcc
     6001 ctttgacacc gatttttgtg gcaattggca atcgtaaaac ttcactataa gtcggtgcag
     6061 ttccaacaga atctggcgtt gccatcatcg caattaaaat gtcgtccaat ccttcaaaat
     6121 aaaaagtatc ttgttttccc aattaaaatc acccttccca taaatcaagt atttttctag
     6181 tcataatttc ttcaattttt tctttgtttt gttcatacgt accacttgca aaatgttggg
     6241 cacgttgatt tgttgtgcca ttttcggcaa agcgccagta aaaggccgtc tcttcaaatt
     6301 gaactttcac ttgatcgttt tcaactacta cttttatttg atcgcgcata tgtttctttt
     6361 ttaagagcga cttaggaata ttaggaagca actgctttag ataaaagtta gctgcttctt
     6421 ctaaagattc caacgataat tttttcggat caacttttga aaggtttcct aaataatccg
     6481 atatttcaga aaaaccattc ttattacttg gcattttcca cacacctcac atatgtgtaa
     6541 tagttggtta cggtatcgtc gttctcatca ccttgtatac ctgtaaaatc tgaatatgga
     6601 atgccagcat tttgcagcgc ttgttcaata acaactaaat cctgttctgt tccaagtgta
     6661 aaaaaagaga cttggtaata aggtaatttt ttatagactt taccggatgc catttttttg
     6721 ctgttactca catttgagta cacaatgtat ggatacatcg tccctaatct ggctttgtct
     6781 ctgaacactg ctaactttgt tgatttcagc gctgttttca attcatcaaa gctaatcgac
     6841 ataagctaaa ctcaactcca tttctcttgc atcgggattc gtataaatgc gagtaatgtt
     6901 atacgttaca gaatcaattt tgagcgcact taatttctct gtgatggatt tatcccatct
     6961 gactttaatt cgtctgacaa cgtctgtctt ggcttgctgt gataaatatt tttcttgaga
     7021 agtcacaccg agttcttcat agaatattag acgcttaaat tcgtaaattg tagttggacg
     7081 atcgtttccg tctgttcctg ttttgatgtc tagcaattcg gctttccatc tgagattatt
     7141 agtctgtctc ttcggcattt tgaatcgctc cttgcacgat aaatggcgtc atggcattca
     7201 tagctttgtc gagttcatcc tctgaaactc tatattcata ggcaatgccg gcaaccatca
     7261 aaataagata ttcttgttgg ccaccagttg ctgttttgac ataatctttt gccatattta
     7321 aataaaaaga gagcaaagaa tcatccatgc cctcttcaaa atgaatatgt gatttgaatt
     7381 tttcctctaa agacaattct ttagtttgct cttccatctt aaccaccaac tggttttgta
     7441 atttcgtagc gatatactgc cggttcaaat ggagaataaa ccaattgacc atctagcaag
     7501 ttgtaaattt ggaatccaat ttgattttta ccagagaatt tttcaacaag tttttgaatt
     7561 tccaaggcac caataacttc ttgaatttta aatgcagaaa aatcgccaaa atataaaact
     7621 ggcgtgtctg gttcaccctt tttatctgct gcatctgtcc aatccacagg atagccaact
     7681 aattggtaac caattccacc ttctgcttgt gtgaatggcc gcaacaaagg aaatccatca
     7741 tctgttttca ttttttcaat ggcagtcaaa gcagctcgat taataataaa gcgtcccttt
     7801 ttcatcactt ctgtcactgg tgtattttta aattcgatta atgcatcata taatttttgc
     7861 ccagcacctg aagcagttag atctaaaggt tttttaaatg ctacagcctt tttggctaat
     7921 gcaccaggat tttcatttcc agcgtcatca ccattgaaca tataattgat ttctttacgc
     7981 acataagctt ttttcaattc ttccacaaca atatcttcaa ctggaacacc agacattttt
     8041 aataattttt tagttactgt tgccaaagca tcgaattcgg caggattaag caaaatttca
     8101 tcaaactgaa tagctgtttc agcaatatca gttgaacgct ctttcttgtt tacattcgca
     8161 tctgctttct tcacaagaat tggatatttg acatctcctg atgttcgcac cactgttccg
     8221 tatttacgaa gtaaattttc ttcttgagca taagtaataa cttcagatgc aattacttct
     8281 gggacagtaa ctgaaccgtt gccagcttca atccctaaag ctcgagcttc tgcttcagaa
     8341 atatttccag ctacaaaatt agcaaatgct tttcgtagtt gttgatcttt ttgtttcttg
     8401 gtcatttttg cacgtgcctc caatccgttc ttaattgatc caagtaatcc atctcgttgc
     8461 tgttgagtaa tcattccaga acgattttct gaactatctt cactgtctga atcttcttct
     8521 tgatcgttgt cttcaccaga acggctttcg tctgaatccg tactattcga ttgatcatct
     8581 gtattgtcgt ctgtttcatc agttccagaa tctgcgccta attcgtcttt aattccgttc
     8641 aattcatcaa taacactgtc aatttcttct ttcacggctt ctaaatctgc ttcgcgtaat
     8701 tctcctgatt caactttttc acgtaattca gtcaatcgtt gctcacgacg tgccttcatt
     8761 tttttcaata attctttatc catgtatttt tcctcctacg cttctagcgc ttgattaatt
     8821 tttttgatta atttttttct ttcttcgacg tttttttcta attcatcacg acttcttaat
     8881 gcagcttctg tatcttcgta tgctggcaaa ggcacaatag aaacctcgta taattccact
     8941 tcatggattg ttcgaagcat tggttcagaa ttgtagtccc acgtttcttc agtcggcaca
     9001 aaaccaaaac tacattggtt gatgtctcct cgttccatag atttaactaa gtcccttgct
     9061 accgttgtgt ccggtaaatc aacttcgaat ttcaaaccac gttcatcttc ttcaaggcga
     9121 agggttccgc ttttagtacg tcctagcaca ttggaccaat cgtgattgaa caaacaacga
     9181 acatccgaat tactaattgc ctttgagaat gcaccaggaa caatcacttc gcttaagtca
     9241 tcccataaaa gtgtttgact gttgaataca gcagcgtagc cgctaatggt cctcgtatga
     9301 gtttcttcat cggaacgtgt tgaaagattg gtgatgtcaa tcgtgcgaat ttccttcttc
     9361 ttcatttcca tcacctcctt tcaagtcttg atcattcgtt ggtaaggaat catctgttgc
     9421 atttttctgg ccaatcctag ataagtcatt tgaaatatag atagcttgtg tttctggagt
     9481 attctgttta ggaaaaccaa gcatttctgc cacgttatct ggacttgtaa tcccggtacg
     9541 aacgatgttg tagccaatat ttgtttttgt tgagtaagga acaaaatcca aaatattaat
     9601 tttccattcc actctatagc cagaattagg cataaaaaaa agagcggtgt aatgttcgct
     9661 cttgtttttc aatattggtt tgattgcttt gttgtgcaga tacatcatcg ctttttcaat
     9721 atctgtcttc atcagcgatt gatacgtatc aacattgatt cctagaaatt ttcctaagtc
     9781 ttttttgtaa acacctaaat aattcaaaat tgccgcgtca tcaacaggac tttttaatgt
     9841 ctcgatggaa tatccttttc ccaaaggaat catcttaaca gaatgatcac tctcattttg
     9901 cgttccttcc agttgatcca atatagcttt gacaattttt gtttgggcgc tattatttgg
     9961 attgatgtgg gcgtctagtt taagcatgaa cgcaagtaaa ccgcctttag tatatttgtc
    10021 cgtcaaaact ttttcagcgc tcagaacgcc ttctagagtg tttcttgcaa gatcaattat
    10081 tccagcacct tttaatgaat cagttccgat gttcttaatg tgtcgaatca tttgaccagg
    10141 tattttttga ccattcattt caaattcttc ttgaagtcgt tcattgattt tagttgttac
    10201 accgtacgcc aaatgaagct gatccctatc cgttaatggg aatgtctcac cattgatcaa
    10261 taaagtattt gtttccaatt tggtaaattc gaatcctgtc aaataatcat tgggactctt
    10321 caaaatattt agtaagtgat gatctttgac ttcgttgccg tcgggaccaa taacaattgg
    10381 tgtggccaat gccacctgat tagatatgtc ttgaactaat tcataaacat cagaagattc
    10441 catgatagat gaatccgtca catatctttg accataacgt gtgtagtgtc caaaaatatc
    10501 ctcgatatat ccacgttttt ccataaaaga atagactgca ttcgataacc gatcacgtaa
    10561 tttcaatttt tttcaccgcc tttctattta tctatagatg gaacttaggt aatcatctaa
    10621 ctcatctgaa tcaatatctg tcatttgatt catcgtttcc ttatgaccac acaaaaacgc
    10681 cacgaaccca tcaatctttt tctttgattg acgtttactt ggcgcttttt gtccattgat
    10741 gttagtaatt gctacaacgt tcaaagtgca ataaaggaat aatggattat caaattgaat
    10801 tcgtttctca taaaacaacc gttcgacatc gtcaaaagga gcattcaata ctttaggata
    10861 ttgagcaact tcaacgcatt ccaatcctaa gttttctaat ttctcaacaa gtttgtcact
    10921 catcgctgga tcataattca cttgctgaat atcatataaa ttcatgcagt cctctatgta
    10981 ctgcaaaatc tgatcttgat caatcatttt tccgtcgcaa aattcaacga aaccttgttc
    11041 agccaaatca ctgtaaggaa cattatcttc tttttctcga aactctaaat cttcattcgg
    11101 aataaaataa agttgcttta ctttaagaac cgctttacca tcttcatccc atgttgggaa
    11161 gtttaaagat acacaggtca aatctcgtgt acgtgataaa tctaaaccga tataacatgg
    11221 ttcgccactt aaatcaccaa gttcttgtgt ggtaactaaa catggctcta cttgatcctg
    11281 ttcaaagaaa ttatccgcgc cgttcacaaa tacatccaag tgtttcgtta gaaattcagc
    11341 tttggaatga gctgaccgtt gcgctgtttt aaatgccgat tctaaagcag ataaatcgac
    11401 tgatattccc cagttaggat tgcacatttc ccagactttt ctatccgtcc aatcataatt
    11461 tttatttggc tcatagatta gaacaaagtt tgaatcatta tcatcacgtt tcaacacttc
    11521 ttttgcttcg cgatatacac gcattccaac agacgacgaa cctttcccag cagttgagat
    11581 attaaacatc aatggctgtg gtaaagatat ctgagcagac ttaaaattgt catactgttc
    11641 cattttctcc tgtttatgca attcatcgtt caatacaaaa tatggattgg atccctcgat
    11701 attatcaata ttcttggttt gaacaataaa tttatttgag taagccatat cttcatgaat
    11761 atagtcataa gtaatactag aaacagttcc ctttggcccc ctaaatattt tagttccttc
    11821 aagtaggatt ggattgttta agattgtaac tgcaaaaggt ttggcagcat attgcgcttg
    11881 agcaaaatca gatgcgcaag catagcaatc aactgataac gccccttctc cgtacattgc
    11941 atatcctaat gaaccgacag caatcaatgt tttaccattc ttttttggaa tctggacata
    12001 agcctcacga gtaacgcgta caatttggcc tttttcattt tctttaaccc aaccataaat
    12061 ccaagaataa ataaattttt cccagggttc taaaagaaac ggttttccca ccatttctcc
    12121 ttttgtgtga acaataaatg attctaccca atccatcatt tcattcgcgc gatctacatc
    12181 aaaccaaata tcttttcttt ttttccactg ataccagcga tctattgcta aacgaacggt
    12241 cttaggatac ttcttaggtt tctttcttac ttcttttgca aataaatcag cataatttac
    12301 accaggttca atcatttttc agcacctgcc ttcttacgcc atttatttct gtgcgctgct
    12361 agttcatcta ctggctttac ttctgggcgt gtaatttctt catcttttct tgcggtcgat
    12421 cctccagcaa ttagtctacc agtttttgct ttgtttgtta atcctaataa atctagagct
    12481 ttcatcttct tatctgccca agtttctact tgttgtgcca atggatgttt tgattgatta
    12541 gtagctcctg atttattcgt gaatttttgc gtctccggaa atcctttttc cttccacaat
    12601 aaatatttgt gttggtaaat ttcaaaaata tccaagtatg attcgattaa tggatcaaga
    12661 gtgatggtgt acaaatcaga caaattcatt atttctaaga tacgagcttt ttcagcactt
    12721 actttttcat caataatcgc tttacgttgc gctttagtcg tcatttttgt atacaccccc
    12781 ctttgttttt tgaaaaattt gacctaacga tgcgcgtgac tccccgctac cctatctccc
    12841 cacgcgaaaa aattttgaaa atgaataggg gggcttcaat tgaaatacga aggaaaaact
    12901 tttttgtctt ccgtttcgtt ttcaacaatt ggatgacatt ttgaacataa tagcatgaga
    12961 ttgtttggat caagcttaag cagttcgttg tctttgattg gtacaatgtg atggacgtgt
    13021 gctctctttc caaatatgaa ctgaccacac cgctgacaat gaccaccttc tctttcataa
    13081 ataaattgac gcatatcttt ccatgcttgc gttcgataga atggtttgtt ctcatgatga
    13141 taaacagact ttgcttgctg cttcttcttg cgtgatctgc ttgatctctt gtgttcagta
    13201 cagtagatac cctttgctat tttgttcgtg catccgtcaa actgacagta tttcattcta
    13261 cttcacgaat aagatttatg atatcgcctt ttgcacggat agcaccagga atatcaatac
    13321 catgtttctt agcatatgca cgcaattctt ttgcagtcat attgtccagt tcatccgtat
    13381 cttcagtgga ctgatcatta gtagcttcgt ctccatcaaa attagcagca gtgtttccat
    13441 cgctatcaag aatttcactg ctatgagcta tgagttcgcc attgacagca acaaatgatt
    13501 tgccatcact caaaattcct ttttcttctt ttacttcaaa atttggttct tgatctttcg
    13561 gaacaactac tgtccttttc ttttctgaat cccaatactc tgttccacta atggatgttc
    13621 taattttgat cattgccatt ttaattctct cctttgtaat ttgtacggat tacttttgcg
    13681 cccattcgct cataccattc aatcgtttcc tgcagattgg gtagagtgtg tgacaataaa
    13741 gaaataacta acgtattcat tccagttctg taatcatcat tctccacttg cacatgtgca
    13801 tgattaccat tccaattttc tctgtacgga ctattctctg cttcaattgc tttcttataa
    13861 actttagcca aacttgattc tacttcaata ctaagtaccg cttcatgaaa atcattcatt
    13921 tgtttactct cctatcagat attttgtggt atgatttata aaaaagatgc gaggtgtttt
    13981 aatgcttcaa gaagttaata ttaagtatcg tgatcgtcaa aatacagaga caatttattt
    14041 gccaaatagt tgtccgcatt gcggaaatat aatgactccg tatgtgtatt ttggggtttc
    14101 atcatatagt gcgttcgata atgatagaat ctttggcgta ttagtacagt gtataaatga
    14161 tgagtgcaac aaattttata gtttacaatt tataaatacg tttaatgaag atgaaggata
    14221 ttctgaaaat attttaatta aagattatta ccgtccgccg attaaaatag atttaccaga
    14281 aaatattgaa aaagtttctc ctacatttgt tgatatttat actcaagcca cacaagctaa
    14341 atctgagcaa ttggaacaaa ttgctggagt tggttataga aaagctctag aatttctaat
    14401 taaagattat gcaatatcta aaaattcaga ggatgaagat aaaataaaaa aaatgttatt
    14461 aggtaaaaca attgaaaatt atttgaatga ttttcctaaa ctccaaagat tagccaaagc
    14521 tgctacttgg attggtaatg atgaaacgca ctatgttcgt agacatacta ataaagatgt
    14581 tcatgatatg gatgcattta ttaaatcagc agcgcaattt atcgcggctg attatgatgc
    14641 tgatttagct gatcaattta taaatggaaa taactttatg ccaactacta attaaaagaa
    14701 taaaagagcc acagatacca attaataaaa cggttgggat atcttggctc tttcatattt
    14761 ttttgacact aatagaatat catgctgcta acaatgttta catagctaca atgaccgaac
    14821 atttagtgaa cagtgtaatt ttagaataaa gagagttgtt ctttgtactt ctcgctattg
    14881 taaaaatcaa tttcgttttc ttttttcaat cggtcagctt gtctgtgttc atactcatct
    14941 aaaaagttca atgtctttct aatttctgca tgtcgctgtc tgacatacga tgagctatac
    15001 ccaacagatt cagcaatatc ttctaagctc atttgatcaa catatttcat cttaacaatt
    15061 tgattatcga taccagaaaa gctatctatc agcaataaca tttcttcttt ttgctcgatc
    15121 aacaattcca attcattttc tatcttttgg atattctctt ctaaagaaga agttctcgaa
    15181 ttcttttcga tgcggacgtt tgctaaatca ccacagaccc atcgattcaa ttcaagctta
    15241 cttttattaa gattccactt taagtaaaga atctgctcat ctagttcttg gtaatctttt
    15301 aaccaatgaa atctcacaaa cgccacccct tatggtagaa tagtattgcg ctgctatctc
    15361 gaaaggggta gcttttttat tttttcttag ccgttccatt ctggattgcc ttttgttcca
    15421 aacgtcgttt tttcttctta atctttgatt ttgtttttcc catacaattc tcctttccga
    15481 aaacacattt tgttcgattt ttaatactaa ataaaagttg gccagaattt ttcgttcgtc
    15541 tttactcatc tttttttgaa taagattact agcataaaaa tagttagtac cacgaaaatg
    15601 aacaggtaaa tcaattacgt tcaccttctt catgccagtt atcagccact agaatctttg
    15661 cgttagtgcc gccaccgttt tcttttttgt atttttcaaa tgctttataa gcagctgttt
    15721 ttgatttata gatttttccg gaaccgactg ggaacatcca tgtgccctct gtgatagcta
    15781 agatgtatac tttcatttaa ttcacccctt taatccccaa cactacatat ccggacttct
    15841 gcatgtaatc agtaatataa gtgatctctg ctttgtatga gtcaccagtg taactaaatg
    15901 ttggtctcgt tagtccaggt aattcatgtt taatgtattt tttatattca cgtagtatta
    15961 actgatcacc aactttgaag tcacgatcat tcttgcggat ctcgaattgt ttgcgtccgc
    16021 tcgtcactgc ttcaaaatat tctggtagta tttttagttc gtggatcatt ctgtttcctc
    16081 cttcaaaatt cgctcatcat caaaaagtga atctccacaa aatccttctc ccaaatattt
    16141 atcgttcatg tataagtcaa ccaaatattt gtgatctgct tctcgatatt cattaatatt
    16201 aacgatcttt attttgtaaa cattaccttc gtcgctcact atcttgaatt gttctctgac
    16261 tttcaccacc gttcctcctc tttttgaaaa aattttagtg tttttgtaag accccctaaa
    16321 tcagcttttt tatttgatat aatacttgta tcgattaatc aaatcgaaat taaatttaaa
    16381 aaggtgattt atcatgaata tcaacaattt agtaaaactc gttgaacaac gttttaaaga
    16441 atcaggatta gaacaattaa aaaaagataa ttctccagaa ttattttcta attttaccga
    16501 agacgacatt cctactctta aacaattaaa atattattct gattattgga cgcaaactcg
    16561 tgagaatgaa ttaaatttag aaaaactcat tattaaaaag aaatagcaac tccagcccac
    16621 acggctggtt ttttagtttc aacttccctc cttacgggtc aaaatcatcg gttccggcat
    16681 aatctgatca tcctttagca acaaatcagg atattttttc cttagcttct tattgttcgt
    16741 gtaagttttc aatagccatt ggttggcttc gcttttgctt tctccagaaa aataaatttt
    16801 ccctgtttgg atgcctgcaa gttgaatcat cattttcacc tcaaatcaaa ttttttctgc
    16861 tagatggagc aaaagcaatc cgacatcaag aatcttttga cccattattt cagctacttt
    16921 gctcggctta actccttgag aaaagagcaa gcgtgcttgc tctatctctt cgtgagtcca
    16981 aataaatttg gcttcctcaa ggataattac tggatcagtt gctctcattg ttcctctgga
    17041 aaaatgatgt cattcttatg cttggaccag gtatctgcat atggaacaaa gtattgtcta
    17101 gctaattcga tttgatcaat taaagcagtt tctgataatt catggtctgc agcaatttca
    17161 ttcatactat cgccttcatc taaacagata agaccgttga cgttatcgat ttttacattt
    17221 gtgactgctt gactttctcc acgctcataa tattctacag ttgatactga tacatcagct
    17281 tcggagttta attgcagaat ctgttactgc cgggataatt taatattctt ttcataattc
    17341 accttttttc ctactgacat cgaatatttt tcatgttatg attagccgtg aaaggagagc
    17401 tatattatgt gtttacacat gatgtcctta gctcattcgg ttctttggaa gcttttttgg
    17461 aaataactct caggttcttg acgcaaatct catttattct ttgaaacaaa aaacttccat
    17521 tttccgagag ctttggatca cttcaaaaga gatttgcatt tatatttctg tgaccttgag
    17581 tcgcgtaaag aaccttacag caatggcggc aattccactt tcaggaaacc gccttttttc
    17641 attgatattg gtggttagcg gactacccat tttctttcgg cagtgccaaa ccacaaatga
    17701 tctgtgttga tgtttaggta gttgtatacc agataagcta aatccaaagt gcctgcatct
    17761 tcaagacgac aatattccaa aaattctccc atagctggac ataaaaatcc tggagctatc
    17821 atatcccaac agttaatagt gcaaagaaat tcgtttagct tctgaacgtt ttctttggtt
    17881 tcacgaatta caacatactc caattcttct ccgctggcag agcattccaa aacttcaaat
    17941 tgattaagaa atggtagaac atatgcttca aacatcaaca ttccatcttt ctgtttttgc
    18001 acttgttttg catcaatcat gtctatcctc ctattcagtt atttcttcca ttaatggaat
    18061 tatttcaggt cactggactt aacgaaaaca ccattgacca tctttccagt ccgacctttg
    18121 atttcgtcat aagcaaaatc caagcactcg tataaatcca tatcattttg cattgccaag
    18181 atgatcaagg ttactactac atcgccaatt ccgtctctta aaccatgttc atcttttcta
    18241 gctagagaag cggcaacttc cccgatttct tcgaccgttt ttaacatttg cttgctgaaa
    18301 tccgcttgat ccaatccctt atcttttgcc cactgctcta ctttcgcgat tagttcgtcc
    18361 attatttctc ctccacatac ctaaactgtc ttccttttga atcaatccat aagctcctag
    18421 ctctatccca aataatattt ttgctcagac cagtaatttc agataactgt ttagcggtac
    18481 ccgttactag aattcgatca ccatgccaga ttgcaatctt tctcggcgtt ctccgtttgg
    18541 gcttttcagt ccacattgat ttaccgagct tttggacttc tgcaactatt tttttatctt
    18601 cctgccaatc ttctgaataa gtcaattcga taattcgctg cattgccgct ttcttatcca
    18661 tcccgacatt ctcctttcag taatttgagt acttgatcaa gtgcgctctc acgtccgcca
    18721 tgaaatgtgt tgagccactt gtcttcgtac gacacacttt gtcttaaagc ttcttgatgc
    18781 attaattcga tctgtgctgt aaatgtcttt aggtccatct tgtttacacc tgctcaagtt
    18841 cattaagatg tttttgcaag cctttaacac aatcaatgaa tagtaatttg gtatatgcta
    18901 aatttcttaa ttgcgttcca tcgatataga gtgcgaaata gtatctgagt ttactccaac
    18961 tcgaacgatc attcttaatt ccttcaattc cagcttcttc gagttgatca tatacgtctc
    19021 tcaggacgtc taattcctcg ccctttttat aattcgctat ttcattaatt agttctagat
    19081 aatcgatctt catttttcca cctcttagaa tggtgctttt gattgtctat tagctcgttc
    19141 tagcgctttt ttcttgagat aggcttcttg gtcgattgcc cattcaggaa gcttctctcg
    19201 tcttcctgtg cgcttgtatc cactgcttgc gttcttaggt tcactttttt ctttccttgc
    19261 ccaacttcga atagttgcca aatagttttt ataagtctta ccagatgatt cacaatactc
    19321 tgacagtcgt tcgattcgct cttggtaatc attagggaat tctgttttga gtttctccat
    19381 ctgctcatct gacaaaagaa catttttata ctctccgtat ttatgacgga cgggcttagc
    19441 cttcgatttt ttcgaaggcg gtaactctct tatatattct tttgtattat taaatgtatt
    19501 attaatagat gtattattat ctttgacttt ttcgtcaata ggggtattgc gtttttcgtc
    19561 aatagggtat tgattaattc gtaggtacct attgattatt tgattggtac cctctttgta
    19621 aatgatttcc cgattcaagt atccaaactt aatcaaatca cttacccatc gcgatatggt
    19681 ctctttattc acaccatata aatctgcaaa gtactcattg cctgcccaac aaaagcctct
    19741 ttcattacac aaggccgtta tctctccgta taacaactta gtatttggtt taagtctttt
    19801 gtcgtacctt acgttggctg gtataatcgc ataataactt cgatgttctg tcatttttcc
    19861 cctccaatat ttaacttttt gattgttttc tggtttaatt tgatcccttt gatttgatat
    19921 ttatttttga aattaatcac acctattttg tgcttctctg tgtgatggat tctgcagagt
    19981 gctgcaaatg tgtactctg
//
LOCUS       DADQDV010000057        18504 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.058, whole genome shotgun sequence.
ACCESSION   DADQDV010000057 DADQDV010000000
VERSION     DADQDV010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 18504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18504
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.058"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            99..746
                     /locus_tag="J8S10_002120"
     CDS             99..746
                     /locus_tag="J8S10_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HAZ9630700.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     gene            1139..3784
                     /locus_tag="J8S10_002121"
     CDS             1139..3784
                     /locus_tag="J8S10_002121"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HAZ9630701.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            4094..5407
                     /locus_tag="J8S10_002122"
     CDS             4094..5407
                     /locus_tag="J8S10_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HAZ9630702.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            5397..6050
                     /locus_tag="J8S10_002123"
     CDS             5397..6050
                     /locus_tag="J8S10_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAZ9630703.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            6105..6797
                     /locus_tag="J8S10_002124"
     CDS             6105..6797
                     /locus_tag="J8S10_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
                     /protein_id="HAZ9630704.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            6947..7147
                     /locus_tag="J8S10_002125"
     CDS             6947..7147
                     /locus_tag="J8S10_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAZ9630705.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(7401..9080)
                     /locus_tag="J8S10_002126"
     CDS             complement(7401..9080)
                     /locus_tag="J8S10_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HAZ9630706.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(9082..9294)
                     /locus_tag="J8S10_002127"
     CDS             complement(9082..9294)
                     /locus_tag="J8S10_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HAZ9630707.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            9687..11417
                     /gene="efrA"
                     /locus_tag="J8S10_002128"
     CDS             9687..11417
                     /gene="efrA"
                     /locus_tag="J8S10_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HAZ9630708.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            11414..13174
                     /gene="efrB"
                     /locus_tag="J8S10_002129"
     CDS             11414..13174
                     /gene="efrB"
                     /locus_tag="J8S10_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HAZ9630709.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            13269..13466
                     /locus_tag="J8S10_002130"
     CDS             13269..13466
                     /locus_tag="J8S10_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630710.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            13619..14104
                     /locus_tag="J8S10_002131"
     CDS             13619..14104
                     /locus_tag="J8S10_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HAZ9630711.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(14208..14801)
                     /gene="clpP"
                     /locus_tag="J8S10_002132"
     CDS             complement(14208..14801)
                     /gene="clpP"
                     /locus_tag="J8S10_002132"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HAZ9630712.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            14981..15508
                     /locus_tag="J8S10_002133"
     CDS             14981..15508
                     /locus_tag="J8S10_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP domain-containing protein"
                     /protein_id="HAZ9630713.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            15599..16336
                     /locus_tag="J8S10_002134"
     CDS             15599..16336
                     /locus_tag="J8S10_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HAZ9630714.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            16340..17257
                     /gene="miaA"
                     /locus_tag="J8S10_002135"
     CDS             16340..17257
                     /gene="miaA"
                     /locus_tag="J8S10_002135"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HAZ9630715.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            17259..18488
                     /gene="hflX"
                     /locus_tag="J8S10_002136"
     CDS             17259..18488
                     /gene="hflX"
                     /locus_tag="J8S10_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HAZ9630716.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
BASE COUNT         5984 a         3200 c         4022 g         5298 t
ORIGIN      
        1 atttgtctca cacccttttc cttcctactt gtaaccttgc tcccgtgtta gaaacatgtt
       61 acactaaata tgtgaaatta ttaacaagga gcgtcgttat gcgagaaaaa acagatacac
      121 tgccaaaagc aactgcgaaa agattacctt tatatttacg ctacttgaag atgctggatg
      181 actcaggtat aagtagaatc aaatcaaatg agttcagcga aatcacccaa attccttctg
      241 caacgatccg cagagacttc tcgcaattag gcgagctagg cagaagcgga tatggctatg
      301 atgtcccttt tcttatcgat gtattcaata atatccttaa tactaaagaa gaaaaacgaa
      361 tcgcattagt aggatatgga aatcttggca aagcattgaa acacaacaat tttagaagaa
      421 atgaaaatct aaatatcgtg tgcgtctttg ataatgatcc agcactgatc aatcgagtaa
      481 ttgatggaga aatgatctat ccgattgatc gtttcgcgga gatagccaaa gcaaaaaatg
      541 tgacagtagc aatctctacg gtaccaagta aatattcaca atctgctatt gatgaaattg
      601 tcaaaggaaa tgtaaccgct atacttaatt ttgcgcctga cagagtaact gtcccagctt
      661 atgtcaatgt tcaatacatt gatttgacaa ccgagttgca gacgcttatt tactttgatg
      721 agaattactc agaagttttt tcttaggaaa atttgagtag gcttattgat cttgcgagaa
      781 ctcgtcgtaa ttctttcaaa aattttttag tactaaatga agtggttttt tcacgaccac
      841 ttgttgacta aaaaaaaaaa ccattgtaga atgaagcata acgctgaaca agaggagtaa
      901 ctggcacatt cattcttaga gagagaacta tctgctgaaa ggttctcaat gacaaccagt
      961 gaaggtagct tgggagtttc tgtcttgaat ggagtagaga tagacgagtc gtgatcgtta
     1021 actcacttga gaggcaataa tgattgatta ttgcaattta ggtggtaccg cgtaaatcat
     1081 acgtcctaga atacgaaagt attttaggac gttttttagt ttaaaggagg aaaacagcat
     1141 gacggaagaa aataacctat caacaaaata taatccgcaa gaagttgaag ctggacgtta
     1201 tcagcattgg ttagaacaag atttgtttaa accgagcgga gataaaaaag caaaacctta
     1261 ttcaatcgta atcccgcccc caaatgttac tggaaaactt catttagggc atgcttggga
     1321 tacgaccttg caagatatgc tgattcgtca aaagagaatg caaggatatg atactttatg
     1381 gctgcctggt atggaccatg caggaatcgc gacacaagca aaagtagaag cgaagcttag
     1441 agagcaaggg atttctcgtt atgatctagg tcgtgaaaag ttcatcgatc aagtgtggga
     1501 atggaaagaa gagtatgcga gccacatccg cgaacagtgg gctaaaatgg gcttatcttt
     1561 agattacagt agggaacgtt ttacattaga tgatggatta tctgaagcag tacgtaaagt
     1621 ttttgttacc ttatacgaaa aaggtttgat ttatcgtggt gaatatatca tcaactggga
     1681 tcctcaagca cgaacagctc tatctgatat cgaagttatt cataaagata tcgaaggcgc
     1741 cttttatcat atgagctatg aactagcaga tggatcaggc gtagtagaaa ttgcgacaac
     1801 ccgtccagaa acgatgttgg gagatacggc gattgctgtt catccagaag acgagcgtta
     1861 tcaagcgctc atcggcaaaa aagtgattct acctttagtc aataaacaaa tcccaatcat
     1921 tgcagatgaa tatgtagata tggaattcgg gacaggtgta gtaaaaatca ctccagcaca
     1981 tgatccaaac gactttgagg taggtaatcg tcatgatctt ccacgcgtaa atgttatgga
     2041 tgatgatggt acgatgaatg aactagcagg aaaatatgct ggaatggaac gttttgctgc
     2101 tcgtaaagca atcgtgcaag atctgaaaga aatcggtcga ttgattaaaa tcgatacgat
     2161 gatccacagt gtgggtcatt ccgagcggac aggtgtcgtt gttgaacctc ggctgtctac
     2221 tcaatggttt gtaaaaatgg cgccgttagc gaaaaaagcc attgataacc aagaaacaga
     2281 tcaagcagtg gaattcttcc ctccaagatt caatcaaacg tttttacgtt ggatggaaaa
     2341 tgtccatgat tgggtaatct cacgacaatt atggtgggga catcaaattc ctgcatggta
     2401 tcacaaagaa acaggtgaaa tgtatgtagg gatggaagca ccagcggata gtgaaaactg
     2461 ggtacaagat cctgatgttt tagacacttg gtttagttca gctttgtggc ctttctcaac
     2521 aatgggctgg ccagatacgg aaagcgaaga ttataagcga tacttcccta ctagcacttt
     2581 agtaaccggt tatgacatca ttttcttctg ggtaagcaga atgattttcc aaagcttgga
     2641 atttactggc gaacgtccat ttgagaatgt cttgattcat ggattgattc gtgacgaaca
     2701 agggcggaag atgagtaaat cattaggtaa tggaatcgat ccgatggaag taatcgaaaa
     2761 gtatggagca gatgctctcc gctggttctt atcgaatggt tctgcaccag gacaagatgt
     2821 ccgcttcagc tatgaaaaaa tggatgcttc ttggaacttt atcaacaaaa tctggaatgc
     2881 ttcacgtttc gttatcatga atatcgaagg aatgaccgta gaagagatcg atttatctgg
     2941 agaaaaatca gtggctgacc ggtggatcct tactcgtttg aatgaaacga tcgaacgagt
     3001 aactgagcta tttgatcgtt ttgaatttgg tgaagcaggt cgacaactgt ataactttat
     3061 ctgggatgat ttttgtgact ggtacatcga aatgagtaaa gaagtacttt atggagatga
     3121 tgctgtttca aaacaaacca cccgtagcat cttagtccat acacttgatc agatcctacg
     3181 tttattgcat ccaatcatgc cattcgttac agaagaaata tgggaacata ttcctcatca
     3241 gggaaattct ctagtagtgg cagaatatcc tgttgtacgt ccagagtttg atgatgaaac
     3301 agcttctaaa gggatggaag tattgaaaga attgattcga gccgttcgaa atattcgttc
     3361 agaagtgaat acaccattgt ctaaaccaat tacgttgcta attaaaacaa acgatgctaa
     3421 aatcgatcaa tttttagttg aaaatacaag ctatatcgaa cgcttctgta atcccgaaga
     3481 gttgacgata tcaagtgaga tcactgcgcc agatctagcg atgtcagctg ttctgacagg
     3541 tgcagaaatc ttcttgccgt tagcaggatt gatcaatatt gaagaagaaa tcaaacgatt
     3601 agaaaaagaa ctggaaaagt ggacaagcga agtaaaacgt gtccaaggaa aactttctaa
     3661 tgaacgtttt gtttctaacg cgccggaaga agtagtagag gcagagcgtg caaaagaaaa
     3721 agattattta gagaagcaaa cggctgtcaa agaacgaatc gaaagtttgc gtactattca
     3781 ataagaatag aaaaagagag tgtgaaatca gctagctatt actaaaagct agctgattga
     3841 acatcgttac aggaaagagt ttgagcctca ctcttagctt cgattcataa ggagatgtga
     3901 cataaatttt gtcgcatctc ttttttagtc tactcttatt atgtaggaga aggagggagg
     3961 tggatcatgt atcaagagtc aataaagtag ttgataaaat cgttcctctc tctgtttctt
     4021 ttctctttgt catactttta tttttcttat gtgttctatt tgttataata aaagagaaat
     4081 gggggaattg ttgatgacga ttgaagaagc aatagaatgg atccatagtc gattaccatt
     4141 tggttcacgt cctggccttg accgagtcga agctttatta gaagtggtag ggcatccaga
     4201 gagaaaagta aaaacgatcc atatcgctgg aacaaacgga aaaggttcta ctgtagctta
     4261 tttgagaagc ctattagaag aggctgggct gacagtaggt acatttactt caccttatat
     4321 cgaaacgttc aatgaacgga tcgcaatcaa tggcaaaagc attccagaca atgatttgat
     4381 ccagcttgta aaaaaatatc agccactgat caaacaactt gatcaatttg aagcagtagc
     4441 tggtattact gaattcgaga cattaacagc aatggcattt gattattttt tgatgaagaa
     4501 agtggacgta gcgattatcg aagttggctt aggcggctta ttggattcta ccaatgtagc
     4561 tgtaccaatg ctgacgggaa taacaacgat tggacttgat cataccgaaa tacttggaga
     4621 tacaattgaa gaaatcgctg cacaaaaagc tggaatcatc aaacaaggcg ttccagtagt
     4681 aacaggaaat attgccccag aagcttttac tgtcatccaa caaacagcta aagcaaaaaa
     4741 tgcaccgctt tatgtatacg gggaaaatta taaaataaac tatctgcatc ctgatgagat
     4801 gtggggagaa gtatttgaat tttttaatga aataggaaag atccctcaat taaccactcc
     4861 gcttttaggg caacatcaag ctgaaaatgc aggagtagcc atcgaattgt attttgttta
     4921 ctgtcaattg gaaaagctgc ctttccgaga aaaagatgtt ttgaagggat tgaagaaatc
     4981 tcgatggcca ggaagaatgg agcgtttgag taacgagcca ttagttgttt tagatggtgc
     5041 ccataatacg catgcaatga accggcttgt tgagaatttg aaaaaagaat tcaaaggata
     5101 tcaaatcaac attttgtttt ccgccttacg aactaaaaat gttagagaaa tgctagaacg
     5161 attgcagcaa gtaccaaatg tccatattta tttgacgacc tttgaacatc caaaagccat
     5221 cgaattaagt gaagtatcag atttagcaag tgagagagta tcaatcgttt cattgtggca
     5281 attcggatta gcagatatat tggaaaagat gacaaatgaa gacgtattag ttgtgaccgg
     5341 ttcactttat ttcatttcag aagttcgcca tttattaata caattaggag gagatcatga
     5401 agtataatgc agtgattttt gacatggatg gtttgctgtt cgacacagag ttagtgtatt
     5461 acgaagccac acaagtagta gcagacaaga tgggttttcc ttatgataaa gacctgtatt
     5521 taaaattctt aggtgtttca gatgaagaag tatgggcgaa ttatcatatg attttctcgg
     5581 aatttggcaa aacaagtgta caaagattca tagatgattc ataccaggaa acgcttgaac
     5641 gtttttcgca aggagcggta caaatgaagc ccggtgtgtt ggaactcctc tcttttttag
     5701 aagaacatca gattcccaaa gttgtcgctt ccagtaacca acgagcagtc attgaacttt
     5761 tattgaagaa gaacaatctg tttgaacgat ttgagacgat tgtttctgca gaaaatgttc
     5821 aacgagcaaa accagaccca gaaattttct tgttagctaa tcagaagcta ggtacagcga
     5881 agaaagaaac attgatttta gaagattcac aaaatggtat tttagcagct tctgcggctg
     5941 agatcccggt agtcatggta ccagatctgc ttccaccatc ccaagaattg atcaaaaaaa
     6001 cagctggggt tgtttcttct ttacatgaaa tccctgcatt gttaaaataa aaatccatct
     6061 cttttcgtat cttattttag ataagataga aaggagatgt ttttttggga aaacgattga
     6121 tcaaagaagt acctactagc tctttaccaa gggaacgtat ggaaatttat ggcgcggaag
     6181 ctttatcgga tcaggagctt ttggcaatct tactgcgtac cggtcaacac ccttatagtg
     6241 tgatgtcgat tgctggaaat ctgttaaaaa cgtttggagg actggcctct ttacgacagg
     6301 ctactttgca tgagttagaa gagattcgag ggataggacg cgtgaaagca atcgaaatca
     6361 aagccttgat cgaattaggt cgacgaattc agacggatca tgaaagagcg gctccaccgg
     6421 ttcgtaccag ctacgaattg gcccagcaat tgattctgga aatgaaagat cacaaacaag
     6481 aacatttggt ttgtatttat ttggacacga agaatcaagt gatcttaaaa aaaacagtgt
     6541 tcatcggttc gctgaatcag tcagtcgctc atcctagaga aattttccat tatgctgtac
     6601 gttattgtgc agcaaggatc gttttagcgc ataatcatcc ttctggtaat gttattccat
     6661 cgcagcagga tatgaatttt accaaaagga tacaaaagtg tggagaaatg atggggatca
     6721 ctgtactgga ccacttgatc atcggacgca aacgatattt tagtttgaga gaagaaggaa
     6781 tgatggaaga gaagtaagtt gctttcttgc aaaaaaaatg aagcaagtgt acaattatat
     6841 tgtaattttg tttgggaata gaagttgaaa catctgttgc acctctatcg tacacgagca
     6901 atgttacaat ttaaattagt gcttttggca cgaggaggat attattatgg aaaacggaac
     6961 agtaaaatgg ttcaacgctg aaaaaggatt tggatttatc tcacgtgaag atggaagcga
     7021 cgtattcgtt cacttctcag ctatccaagg tgacggattc aaaacattag aagaaggtca
     7081 agcagtgact ttcgacgttg aagaatcaga ccgcggccca caagctgcaa acgttgtaaa
     7141 agcttaattt tatctgtaaa tcaaattgat ggtagacatc aatttttacg agagaacaaa
     7201 gcgagtaaca aaaatacctg ccacaagaga caatttctct tgtggcaggt atttttttgt
     7261 atgaaaaagt aaataaattt aagaggctat gaaagagcca ccttgtatca aggaataaga
     7321 acaaacaaaa atggcttctc atgtttttca tttgttttct cttatattca ggacaaggtg
     7381 ctgatttcat aacctcttat ttattcttca tctggtgtca ttaccattgg caaaatcatt
     7441 ggatgtcttt ctgtacgttc gaataagaaa ggctgaagcg cgccagtcat cgcttctttc
     7501 aatttatatt ctgaacagtc aggtccattc aaacattctc ttaaagcgtg gaataagatt
     7561 cgctgagctt cattgatcat ttctcctgat tctcgcatgt agacaaatcc acgagagaga
     7621 atatctggac cagccaagat ttcttttttc ttgatatcca ctgtcgcgac agctaataca
     7681 agaccttctt ctgaaagcag gtgacggtca cgtaaaacga cattaccaat atcaccgatc
     7741 ccgctaccat cgatatacac atctccagcc acaaaatgcc cagcaggacg cgcagaatcg
     7801 ctagttaacg ctaaaacatc gccattttcc atgatgaagc agttttctgc aggaacacct
     7861 acatcttgtg ctagagaagc atgtactttc aacatgcgga attctccgtg gacaggaata
     7921 aaatattttg gcttcatcaa acgaagcatt aatttttgtt cttcttgtcc accgtgaccg
     7981 gaagtatgga tgttattgat ttttccgtga atcacttctg caccagcttc agacagcaaa
     8041 ttgatcaaat gattgacact tgttgtatta ccaggaatag gtgaacttga aaagatcact
     8101 gtatcgtctg gctggatttg gatttgacgg tgagtaccat tcgcgatgcg gctcaacgcg
     8161 gccatcgctt ctccttgaga acctgtacat aggatcatcg tttcattggc aggcaagcga
     8221 ttgatttcgt gtgcatctac aaatgtgccg tctggaactt tgatatatcc taaacgttga
     8281 ccgttgacga tggcattttc catgcttcgt ccgaaaacag cgattttacg accagttgcc
     8341 acagcggcat ctgctgcttg ctgcaaacgg aagatgttag aagcaaagct ggcaaaaatg
     8401 atacgtcctt cgatttttga aaagatcttc aaaatagaat gcccaatcgt tttttctgat
     8461 ttagtaaatg ttggaatctc agcatttgta ctatcagata aaaggcacaa gactccttct
     8521 tccccgatac gagccatttt atgcaagttt gctggttcgc caacaggagt gaaatcgaat
     8581 ttgaagtctc cagtcgctac gatatttcca gaaggtgttt tcaccacgat ccctaatgca
     8641 tctgggatac tatgggtcgt tctgaaaaag ctgacagaag tctttctaaa acggatgatc
     8701 gtatcttcat tgatctcatg gagctctgca tctcgaagca agccatgctc atctaatttg
     8761 tttgtgatca acgctaatgc gagaggacca gcatagatag gaatatttgc ttgtttcagc
     8821 aagtagggta ttccgccgat gtggtcttcg tgcccgtgag taatcaccaa ggcttttact
     8881 ttgtgtaagt tttgtatgat gtagctgtag tcgggaatga catagtcaat tccaagtaaa
     8941 tcgtcttccg ggaatttgat cccggcatca atcaaaatga tttcatcttg gaattgtacc
     9001 ccatacgtat ttttcccgat ttcacctaat ccaccaatag caaagacgcc tgtctcgtta
     9061 tttttgatgg aaagtttcat attaaaactc cactaatgag aaatcagcat tttctttttc
     9121 gtactctaga tgacttcctt ctagaagttg aacgaattca atattgtatg gggtattttc
     9181 ttccacacgt tggcgagcgt ctacatcgct ttttgcctca atgtaaagag attttgtttc
     9241 ttcccgttta gggttgcgta cttttgtttc ttgataataa actttataga tcattgtttt
     9301 gtctccttta tctgcgtaaa gcagtgattt agctagttga tttttttaga caacacaaaa
     9361 cgaggggaca agccacctgg tttttcatat gctttgacta gaatactgga ttcgagtcaa
     9421 agagacaagc ctcgtttttg cttatctgtt cggatatttt ttcaaccgta ccttctgtat
     9481 aaaaaatata caacaattaa ttgttattct agcataaaac agcaaataag tatagaaatc
     9541 aactagattg aaagaaaaaa tcaatgttta tcatcccgct ataatcataa tgactttttt
     9601 atgagagaag tgttctatta ataggctcgt tgtgctatca tttttagtaa tgaaaatgta
     9661 acaaaagatt aaaaggagat gagaaagtga aactaatgtg gcattatacc atgcgttata
     9721 agaaattctt gtttttcaat ttcatatgcg tatttggttt tattttgatt gaattaggac
     9781 ttcctacgat tttagcacgt atgatcgatg taggaatccg caatgatgat tttgattatg
     9841 tgaagcaaca agggatattt atgatcgtta ttactgtaat cggtattatt ttgaatatct
     9901 tgttaggtta ttttggttcg aggattacga ctaatatcgt agcagatatt cgagatgatt
     9961 tgttcgaaaa gatccaaagt tattcgcatc aggaatacga aaatctaggc gtatcttcat
    10021 tgatcactcg tacaacaaac gatgcttatc agatcatgtt gttcctgcaa aatattttac
    10081 gtatcggttt tatggcacca atgatgttca ttgtcagttt gtacatggtc atgcgtacaa
    10141 gtgtgacact cagtttgtat gtagtaggtg cattaccttt actattattg gcagtcgtag
    10201 cgattgctaa ggtgtctgaa ccgttatcta aaaagcaaca aaaaaactta gataaaatca
    10261 acagtatctt gcgggaaaat ctttcaggat tgcgtgtgat tcgtgcattc gtcaatgaaa
    10321 agtttgaaga aaaacgtttt gctgtagtca atgagaatta tgcttctagt tcaaaaagct
    10381 tattccgttt gatggctgtt gcacaaccgg gtttttattt cttatttaat atcgtaatgg
    10441 tattgatcat ctggagcggg gcagtgcaaa tcgatgcagg cgagcttcgt gtaggagatt
    10501 tgattgcgtt tatcgagtat atattccatg ccttgttctc attcatgtta tttgctagtg
    10561 tgttcatgat gtatccaaga gcagctgttt cagctggacg tatccaagaa gccctagatg
    10621 ccaaaccttc gattgtagaa gatccaaatg gtatatctga tacaaaaact aaagggtata
    10681 tcgaatttca aaatgtaaca tttgcttatc caggccattc gcaagagcca gtgatacgaa
    10741 atgtcagttt tacagcctct ccaggagaga ccgttgcttt tattggaagt accggtagcg
    10801 gaaaatctac gttgatccaa ttgatccctc gcttttatga tgtgagtgaa ggaaagatct
    10861 tgatcgatgg agtagacgtg agagattatc ggctaagcaa gttgcgagat aagattgggt
    10921 ttattccgca aaaagcgctg ctatttactg gaacgattgc agataatttg cgatacggga
    10981 aagaagatgc tacgcaagaa gaaatggaac gtgcagctga gattgctcaa gcttcagaat
    11041 tcatttctcg aaaaccagat ggatttaatg aacatttatc agaaggtggt tccaattttt
    11101 caggtggaca aaaacaacga ttggcaatag ccagagccat catacgccgt ccggaaatct
    11161 atatttttga tgacagcttt tctgcattag attatcaaac ggatgcgaag ttacgtgctc
    11221 gtctgaaaaa agaaacgaca gaatctactg tattgatcgt agcacaacgt gtgggaacga
    11281 tcatgcatgc agataagatc atcgtattaa atgaaggaga agtcgtcggt atggggacgc
    11341 atcgggagtt gttggaaaaa tgcccgattt attatgatat tgccgcttct caattatcaa
    11401 aggaggaatt agcatgaaaa aaaccttttc ttccttaaaa cgtttagctc gatatatcag
    11461 accgtatcgt gagacttttc ttttagtgat cctatttaca gttctgacag tggctttcaa
    11521 cgtggctttg ccatatgtta caggacttcc tactacagaa atcagccgta atattgccaa
    11581 tggcgaatca atcaattttt cttatatatt caaatgtctc atttggatca cagttgttgg
    11641 aatagggtat tgtatttcgc aattactttc tggtgttttg atgacaaatg tcgttcaaag
    11701 tgccatgcat gatttgagaa gagacataga agaaaaaatc aatcgtcttc cggtttcata
    11761 tttcgataaa aaccagcaag gaaatatttt gtctcgtgtg acgaatgatg tagatgcagt
    11821 cagcggtgct ttacaacaag cttttattgg tatcgtaaat gcgatattgg gaattacgtt
    11881 ggctgcagca atgatgtttt atatccagcc gatgatggcg ctgatctcta tgatcatgat
    11941 tccaacatcg atctggatct caaaacgagt gatcaatgct tcgcagaaat attttcaaag
    12001 catgcagaat tctcttggtg agctaaacgg ctacgtccaa gaaaatatga caggttttag
    12061 tgtattgaaa gtatatggac gcgaaaaaga aacattggaa ggattcaaaa aagttaatca
    12121 cagcttgaaa tactttgggt ttcgtgcagc attcatttct ggcttgatga tgcctctagt
    12181 tcaattaact gcctatgcta cttatattgg tatggctgtt ctaggaagct tttatgttat
    12241 tactggggcg atcgttgtcg gtcaactaca agcattcatc caatatattt ggcaaatcag
    12301 tcagccaatg gggaacgtga cacaattgtc ttcagttttg caaagtgcat cagcggcaac
    12361 gaaacgtgta ttcgagattt tagatgagcc agaagaaaaa gaaaacaaag tagatgcttc
    12421 actgccagaa acgattttag gagatgtgac attcgatcat gtcgattttg catatgatcc
    12481 gaagaaacca ttaatccaag atttgaattt tgaagtgaaa gctggtcaaa ccgtagctgt
    12541 ggtcggtccg accggtgccg gcaagacgac attgatcaat ctattgatgc gtttttatga
    12601 cgtagacaaa ggagcaataa ggattgatgg aatcgacacc aaatcaatga gtcgcagtga
    12661 tgtgcgttcg ctatttggta tggtcttgca agatgcatgg ctttatcaag gaacgattgc
    12721 agataatatc cgcttcggaa agcttgatgc gacagattat gaagtagttg atgctgcgaa
    12781 aacagcaaac gtagatcatt ttatccgaac gatgccagat ggatatgata tggccatcaa
    12841 ttctgaggga gacaatgtgt ctttaggaca aaaacagttg ctgacgattg cccgagcagt
    12901 ggtctccgat cctaaaatct tgattttaga tgaagcaaca agttcagtag acacccgttt
    12961 agaagcgttg attcaaaaag caatggatcg cgtgatggag ggacggacaa gtttcgtcat
    13021 cgctcaccgt ttatcgacaa tccgtgatgc agatctgatt ctagtgatgg atcaaggtca
    13081 gatcattgaa aaaggaacgc atgagagttt attggcacaa ggtggatttt atgaaaaact
    13141 gtataacagc caatttgctg aggaagcaga ataagtcata taagaataaa acagtttaaa
    13201 acttattttt tgttctctat tcttgataat ggtaaagtaa agttatcaag aaaagtgagg
    13261 acacggagat ggaacagttt ttaaatgaaa aaattactga agccaaaaga gaagttgatc
    13321 gtttaacgca cgtctgtcag acgaagcctt ttgattcagc tgattttttt gaaaatgagt
    13381 ttcaaatcga acgcttggca gcacaaatag aagtgtacga attaatttta aaaaaagtaa
    13441 tagaagaaaa tatagatgta caataaaaac aggtaaaacg tcagttacca gatactgtaa
    13501 atagacatct ggcctgagca ggttttacct gttttttttc ttatgaaata aatatatgct
    13561 atgatacctt tattcaatag gattagtttc tacaaaaaat gaaaggagaa aaataaatat
    13621 ggaacggttt atagcatcaa atgccacagt gattggtgat gtgacattgt cagaagatgt
    13681 gacgatctgg tatcaagctg ttttacgcgg ggacagtaat tggataaaaa taggacaaag
    13741 aacgaatatc caagatggta caatcatcca tgtcgatcat gatgcacctg tagatattgc
    13801 ggagaatgtg acggtaggac atcagtgcat gctacatggc tgtacaatcg aaaaaggggc
    13861 gctgatcggg atggggacca cgatattgaa tcatgcggtt attggtgaga atagtttgat
    13921 tggtgctgga tcattagtaa cagaaggaaa agttattcct cctaatgtct tggcttttgg
    13981 tcgcccagct aaagtgatcc gtcctttgac aaaagaagaa atacaaaaaa acaaagaaaa
    14041 catccagcat tatgtcgaga taggtcggat gcatgcgcaa ggaaaattca aggagcaaag
    14101 ataggcagta gcatccataa aataaaaaag gatggtcagt ttgagttgac catccttttt
    14161 tatttggttt agataagaga gcttaaaaaa gcttcctttg aaacagatta atttaatgaa
    14221 gaactgtttt ccatgacttc atcgatcaat ccatatgctt ttgcttgttc agctgtcata
    14281 tagttgtcac gatctgtatc tttttcaatc acttcaagcg gttgtccagt gcgttcagct
    14341 aaaattttgt ttaagcgttc gcgtgtttgc aaaatatggc gtgccgcaat ttcgatttca
    14401 gttgcttgcc cttgagcgcc gccaagaggt tgatggatca tgatctcagc atttggtaaa
    14461 gcaaatcgtt taccttttgt accagctgtc agcaagaagc ttcccattga agcagccata
    14521 cccataacaa ttgtttggac atctgctttg acaaagttca ttgtgtcgta aatagccata
    14581 cctgctgtaa ctgaaccacc aggagaattg atataaagat agatatcttt ttcagaatct
    14641 tgagcgtcta agaaaagcaa ttgggcgatg atcgaattag caagatcatc tgttacttgg
    14701 ccgcttaaca tgatgatacg gtctttcaat aaacgtgagt agatatcgta agctctttca
    14761 cctcgtgaag attgttcaat gactgtagga attaaattca taatagagtt cctccttgat
    14821 ttcgtttaga aatagtgtac cataatttag tttctaatac ctaaaatgta gtatacattt
    14881 ttggtcaaaa aaggtcaaat aaaaaactta ggcaaattag tcgcataaac ccgctttatg
    14941 gtatgataag cagagaaaca aaacaaggag gaacaacaga ttgatagttg gtattactgg
    15001 ccttatcgga gtgctgacag gtgctgtagt tgtctatatc ggcatgatac tgcaaatgcg
    15061 tcacttggaa aataaagaac agcgtagacg tgaattggaa ttgaaagtca aagaaatcga
    15121 gacgctgaat caattaaata aaaagatcaa cgagatcttg caaaaacgga caacgctgat
    15181 ggaagaatat gtcagctttg atgcatttga tgattgttat atcacgattg acgattttgc
    15241 gtatctccaa tcattttcag cgcaaaatag tttttatctg ccaaattata ttttagacga
    15301 gctatttaag aatatctccc atcgaaaagt gattttatct ccagatgaaa caatgaagat
    15361 tggtggatat gcttataaag gcggacgcgt gattttagag aattttacgg atagtctgac
    15421 tgaaatgatc aatgaaaaaa aagctcagtt gaagactatg acgcgccagc cgattggttt
    15481 cttctcgaaa gatgatgttt ggagctgata ttttgaagca ttgccgttgc acatgagagc
    15541 gtggtaatgc tttctttttt tcttaatgat acaatagaac tgaacggagt gaagaaagat
    15601 gttacaaatc tatgcccatc gcggaagcag cggcacccac ccagaaaata cgcttcctgc
    15661 atttgcagaa gctgtacgag taggtgcaga tggtatcgaa ctagatgtcc atctaagcaa
    15721 agatggttat ttgatcgtta tgcacgacga agaagtggac cggacgacta acggtaaagg
    15781 gctgattcga gaaaaaacat tggaagaact caaaaaattg aatgcagggg gcaaattcag
    15841 caaagaattt ccagcagcta aagttcctga attgagagaa gtgttaggac tgctcctcca
    15901 aaaaaattac cgagggatgc taatgattga aattaaaact gatcagtatg aatatcccgg
    15961 tatcgaagaa aaattagccg aaacattaaa aagtagagat tggccttttc aacatgcata
    16021 ttgcagcttt catttggatt ctttggaaaa aatcgcatta ctggaaccgg agatacagct
    16081 ggacttattg atgagtactt ctgataaaaa gatccaacta gcagcagaaa ccccttatat
    16141 agaaggagta catccaaaaa atacttggtt gttcgaacat ccagtccagg cagctgattt
    16201 tccaaaagca attcgtgcat ggacgattaa cgatgaagaa gaaatggcca aatgtcaaga
    16261 actcaaaata gatggaataa taactgattt tccggagaaa gctcttcggt ggaaacaatc
    16321 aacgaaaagt aggtaaaata tggaaaaagt attagtgatc gtcggtccga cagcagtcgg
    16381 taaaacagcg ctaagtgtgg aactcgcaca actatttgga ggagagatca tcagtggtga
    16441 ttcattgcaa atctataaaa atctggatat cggtacagca aaaatcaaag aagaagagat
    16501 gaataatgtt ccgcatcatt tgattgatgt gatcgaacct actcaacgtt actcagccgc
    16561 tgattttcag cattcaggtc gacaattgat taccgagatt gcgaaccgag ggcacctacc
    16621 tatcatagct ggtggtacgg gtctctatat ccaatccctt ctatatgatt atcagttagg
    16681 agcgacagaa gaagcgaatc ctgagattag aaaaaagtat gaaacgttag ctgaaacaat
    16741 tggttcccaa gcattatgga atcagttgaa agaaaaagac ccggcagctg ctgagaaaat
    16801 ccactggaac aatcaacgca aagtgataag agctctggaa gttttagaga cgacaggaca
    16861 tagtatcacg gcacctaaag aagagccaaa gcaattgtat gattacctca tgattggatt
    16921 agatacgaag cgtagtattc tttatgaacg aatcaatcaa agagtcgatt tgatgctagc
    16981 agaaggttta gtagcagaag cgcgtaaggt gtatgagctt ggagaagtcc aggccagtca
    17041 aggtattgga tataaagaat ttttccctta ttttgaaggg aaagaaacat tggaagaagc
    17101 aacagaacaa gtcaaactac attcgagaag atacgcgaaa cgtcagttga cgtggtttcg
    17161 taaccgtttg gatgcacagt ggtttgatct tataagtgag ccaaatcaaa aaagtcagat
    17221 tgagcaaaca atcaaaaaat ggctggaggc ggaataaaat ggaagaaaaa gtgatcatcg
    17281 taggggtaga aaccgaagca aaccagcgtt acttttcaga gtcaatggaa gagctagttc
    17341 agctgacgaa taccgcatca ggagaagtcg tattcacaat tacacaaaag agaccacaag
    17401 tggatcggca aacgattatc ggtaaaggga aattacaaga attagttcaa caagcggatg
    17461 cgcatgaagc ggatttgatc atctttaatc atgagctaac tccgagacag agccaactga
    17521 ttaccgatgc tgttggtctt ccggtaattg atcgcgtgca gcttatctta gatatttttg
    17581 cgatgcgtgc tcgttcgaaa gaagggaagc tgcaggttga acttgctcag ttagaatacc
    17641 tgctgcctcg tttagtaggg caagggaaaa cattatctcg tcttggcggt gggatcggaa
    17701 caagagggcc aggtgaaaca aagttagaaa cagaccgccg acatatacgg aataaaattt
    17761 ttgctgttaa gaaagaattg aaagaagtag aagctcatcg agagcgcaat cgccaaaaaa
    17821 gaaaaaatag cgagattttt cagattggac ttattggcta cacgaatgcc gggaagtcaa
    17881 ctatcttgaa tctattgaca caagcggata cttattcgaa agatcaattg tttgcaacgt
    17941 tagatccatt gactaagaga tggcgttttg ctgaaggatt tgagattact gtaacggata
    18001 ccgtcgggtt catccaagac ctgcctacgc aactgatcga tgctttccat tctacattag
    18061 aagaaagtca aaatatggat cttttgctac atgtagtcga tgctagttct ccagatcgta
    18121 ttttacagga gcagactgtc ttaaaattga tggatgaact gaatatgaaa gaaatgccga
    18181 tactgactgt ttacaataag gcagaccaga tcgacccagc gatgttcacg cctacgctat
    18241 tcccaaatgt attgatttct actcagacga aagaaggtaa gatggcgttg atcgaagcaa
    18301 tcaaacgtca gctgatggaa ctaatgaccc cttatacact ttctgtgcca agcaacgaag
    18361 gacagaaatt aagcgagttg agaagacaaa caatggtttt ggacgaagcg tacatggaag
    18421 aaacaaacga atatgaagtt aaagggtttg caaaaaccaa ttcaaaatgg ttaagaaaaa
    18481 accaataaaa ttttattttt ttaa
//
LOCUS       DADQDV010000058        18175 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.059, whole genome shotgun sequence.
ACCESSION   DADQDV010000058 DADQDV010000000
VERSION     DADQDV010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 18175)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18175)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18175
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.059"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            206..394
                     /locus_tag="J8S10_002137"
     CDS             206..394
                     /locus_tag="J8S10_002137"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630717.1"
                     /translation="MYFDILIELYDGDIEKTSLFTDTDKLKTYLYNILDKEDAEFLLE
                     NGKVVIDDYTLYLDSAIY"
     gene            468..701
                     /locus_tag="J8S10_002138"
     CDS             468..701
                     /locus_tag="J8S10_002138"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630718.1"
                     /translation="MFNKALIAEKGEVSLLRPFNVWDMNYHIIDTENNKHYRIDIDDV
                     GDEEYCLLSFEELKELDMDLISEYSWKTTKITD"
     gene            775..1065
                     /locus_tag="J8S10_002139"
     CDS             775..1065
                     /locus_tag="J8S10_002139"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630719.1"
                     /translation="MINNLSLILEGLNQLTKEDNDSLASIKSEITQGGNQVILYIDYV
                     TKEFVLTHDKYNYVYLDSHCINIAITKSMKSVEHYAEQLKHDGYKQITDKWE"
     gene            1071..1382
                     /locus_tag="J8S10_002140"
     CDS             1071..1382
                     /locus_tag="J8S10_002140"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630720.1"
                     /translation="MIARTFKEHRELIEWLRFYCKRNHSDNEKIEIIEGTLQDFDVPE
                     INITELFLTHSTLLPESSQFNILEKYCQAMNLVTSYVKVGSRYQLALQIPKGYLKEKE
                     L"
     gene            1379..1552
                     /locus_tag="J8S10_002141"
     CDS             1379..1552
                     /locus_tag="J8S10_002141"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630721.1"
                     /translation="MRKDFVYINTPDPKADKKALARITNAKEPKQNYRRLQLLCYLLF
                     IIVIELLLVALLK"
     gene            complement(1555..2586)
                     /locus_tag="J8S10_002142"
     CDS             complement(1555..2586)
                     /locus_tag="J8S10_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015991957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage DNA encapsidation protein"
                     /protein_id="HAZ9630722.1"
                     /translation="MTNSLGVKLKEKNLYYSPNNALGFNCLMLFVIGARGIGKTYGYK
                     KFVVNRFIKHGEQFIYLRRFKTELKKIPQFFKTMAKEFPEHKLEVKGKEFYCDDKLMG
                     WAVPLSTWGIEKSNEYPDVRTILFDEFLIEKSKITYLPNEAEALLNMMETVFRDRTNT
                     RCILLSNATSVVNPYFLYFNLQPDLNKRFNLYQDRGILIELCDSKDFAEVKKQTPFGR
                     LIRGTDYEDFSINNEFVNDSDTFIEKRSKNSSFLCAIAFEGKIFGYWIDAETGCVYVS
                     YDYQPNTNHFYAMTTKDHEENRLLMKNWRNNYYLSTVAKAFKNSYLRFDNIVIKNLHY
                     DLFNRMKIW"
     gene            complement(2598..3473)
                     /locus_tag="J8S10_002143"
     CDS             complement(2598..3473)
                     /locus_tag="J8S10_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25"
                     /protein_id="HAZ9630723.1"
                     /translation="MNGIDISSHQTGIDLSKVPCDFVNIKATGGTGYVNPDCDRAFQQ
                     ALALGKKIGVYHFAHEKGLEGTPEQEGAFFLKNIQGYIGKAILILDFEGSNQKDSAWA
                     KAFLDYVYNQTGIKPWFYTYTANLNTTDFSSIAKGDYGLWIAEYGRNLPQGYSQPAPP
                     KTNNFPIVACFQYTSSGRLSGYNGNLDLNVFYGDQKTWDLYVGKKSDQIVAPENKIFD
                     ATSDEFIFTLTKGSTSVFYFDGNTIFELSDPTQLDHIRGTYNHVHGKEIPSMVWTPEQ
                     FDIYLKMYDKKPVYK"
     gene            complement(3473..3865)
                     /locus_tag="J8S10_002144"
     CDS             complement(3473..3865)
                     /locus_tag="J8S10_002144"
                     /inference="COORDINATES: protein motif:HMM:NF016961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630724.1"
                     /translation="MIEYITTWLADDNHMIYGLILWLMVAMIIDFVLGFTIAKFDKEI
                     DFSSFKAKAGIIVKVAEMILVVYFIPVAVKFGAVGITMYVTMLVGLILSEIYSILGHI
                     STIDDNNNWTDYVKKFLDGTINRKDDIK"
     gene            complement(3883..4524)
                     /locus_tag="J8S10_002145"
     CDS             complement(3883..4524)
                     /locus_tag="J8S10_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M23 family metallopeptidase"
                     /protein_id="HAZ9630725.1"
                     /translation="MCHWERPGKLHIEERLDLAQAYSKHIDGSGGGGVKRCYGTPIKN
                     TNLDPSSFMSGQLFGTHAGNGRPNNFHDGLDFGSIDHPGNEMIACCDGTVTHVGTMGA
                     LRAYFVINDGTYNIVYQEFSYNQSNIKVKVGDRVKNGQVCAIRDADHLHLGFTKKDFM
                     TALGSSFVDDGTWEDPLKFLGQCFGDGDNDDNNKGKDDLIYLWLSDSLNGWKF"
     gene            complement(4932..6266)
                     /locus_tag="J8S10_002146"
     CDS             complement(4932..6266)
                     /locus_tag="J8S10_002146"
                     /inference="COORDINATES: protein motif:HMM:NF024120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630726.1"
                     /translation="MEKRIDIQMNKMKEENQKNYVLHPETNPKQVVFDEPLHENENQE
                     SFNKFVDKRKMTTTIDVSAYGVVADGVTDCTPILNKLLEEKSEMGITFYFPPCERDSY
                     YRFANTIELKRDVPVVTFLGSGETTLKFETMTAFNVNIESFNIDGFALWLPQGAQSGK
                     GIFFNDTRNYNRFDFDLFVRNCTLNEGTYVVVARGRGVTFQNCLFSNISQAIIKTAFP
                     DVNSMWQGNDINTRGTGFRGFFVKHNRIHFCTAIIIDNEDDYQNVINFCEISSNTIEG
                     GVSYYRGYAHNLHVQNNNHFLAYGNRNALFEFQDVDQAYIDVDVYSRNSQVEGMNSTA
                     ISRLVVVYGHYRNLRITGKLYRCQGHVITLYGGGVNFYCDLMAQEAPLTDGYRFIQTA
                     DKRVNYDGFIVRGLSNSTKVNTPMIYKAPQTVFYNRKIDHVLTGPNASNVYN"
     gene            complement(6277..6699)
                     /locus_tag="J8S10_002147"
     CDS             complement(6277..6699)
                     /locus_tag="J8S10_002147"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630727.1"
                     /translation="MANKNIQMKDSNENNLYPSVRAENLLDLTRRAELTMTNCELYTA
                     SDKTNAISYLGAIGMIEGMVKFTESLTNPVITTLPEGFRPLRTKRIGCMGKYFTPNPT
                     NTKEIIYVTIMTDGRVSVNENVGKIEYLSLDNCVFPLK"
     gene            complement(6711..7115)
                     /locus_tag="J8S10_002148"
     CDS             complement(6711..7115)
                     /locus_tag="J8S10_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003809099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630728.1"
                     /translation="MADKNIQMKDKDQNRLMPVTIAKNVLIDDSNLELVNAEIKGNAS
                     EAKTLAQQAKTTADGLSTEIATATSTANQALTKGGTAQQTAEQAKTTANSASSVATTA
                     KNTADSAKQTATDLAVRVSSLENTTIQYSVLP"
     gene            complement(7235..7531)
                     /locus_tag="J8S10_002149"
     CDS             complement(7235..7531)
                     /locus_tag="J8S10_002149"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630729.1"
                     /translation="MADIRTQLTSEDGTDNLFPVSKAVNIMTNSGTNVEGELGTLKQN
                     NETMNTSVQNAVVTANQAKDAVSELNVNVGKLTNRITTLESTVANLDGIRYVEV"
     gene            complement(7531..8082)
                     /locus_tag="J8S10_002150"
     CDS             complement(7531..8082)
                     /locus_tag="J8S10_002150"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630730.1"
                     /translation="MIDFNHDKRFDGLPSVFKERFSKYPHTEYRYELLLDEEVSALIA
                     YLNEVGALVNDMSGYLNYFIEHFVEKLEEITTDTLKKWLSDGTLENLINDTVFANYIK
                     EIKRLQILVAETRANSVNILLAKNKPDVADDRTFWYKIQRDDTDYGDDPIDTMRIVAI
                     NKVSGWNTATGDIYLNIKGTEAV"
     gene            complement(8088..8924)
                     /locus_tag="J8S10_002151"
     CDS             complement(8088..8924)
                     /locus_tag="J8S10_002151"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630731.1"
                     /translation="MLLKRYIESFTYYQPELSRKERIEVGRKQLFDFDYPFYDETKRA
                     EFETKFINHFYLREIGSETMGSFKFNLDEYLNLNMPYWNKMFLSNLEEFPIFDDMDYT
                     IDEKQKLLNEIDTNIKANRDESKNQTKQVDQTDNRNKNTRDTGTTDSFSRNTYTDTPQ
                     KDLRIASNGNGTGVINYATNITEDLSKETTSSTGVETNNDKTNQNTRSNASEKETKNT
                     DINKDQNQTKDTITRYKGKKGNTDYADLLEKYRRSVLRIEKMIFREMNKEGLFLLVYG
                     GR"
     gene            complement(8914..9894)
                     /locus_tag="J8S10_002152"
     CDS             complement(8914..9894)
                     /locus_tag="J8S10_002152"
                     /inference="COORDINATES: protein motif:HMM:NF017190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630732.1"
                     /translation="MSRRKGAGLARNNRYTAKSRPYPNEPYSSDVEEISYYEHYRRQL
                     TLLTFQLFEWENLPKSIDPRYLEIALHTNGYLGFFKDPTLGFMVCAGAEDGQIDHYHN
                     PIFFTANEAMYHKRYPVLRYDDDDDKSKCIMLYNNDLKVPTLPSLHRFALDMADINQI
                     SRVNRRAQKTPVIIQTDEKKYFSLLQAYNQIDENNQAVFVDKDMEFDQAFNVWQTNAP
                     YVVDKLRSELNEVWNEVLTFLGINNANVDKTARVQTSEVLSNNEQIESSGNILLKSRK
                     EFCDRVNRVFGDELDGKIDVKFRTDAVRQLQLAAGQSKKDQMSGGLPSAT"
     gene            complement(9909..11723)
                     /locus_tag="J8S10_002153"
     CDS             complement(9909..11723)
                     /locus_tag="J8S10_002153"
                     /inference="COORDINATES: protein motif:HMM:NF028148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630733.1"
                     /translation="MARRYTHVKLLANVPFDNTYAHTRWCKTQQEQESYFNSFPVLNE
                     NTDCSYQRDTQLGGVFRVDKHKDALYACNYLIFKNEETYPSKWQYAFVTDIEYKNDNT
                     SFVTFEIDVLQTYRFDIGIRESFIAKEHPQLYYSNGVPFINTIEESLDYGREYTTTNV
                     TTFHPNDGVNFLVILTSEAMPVGDKEDKSGGSIVGGPSPYSYYLLPLNSSGEVYKPNG
                     AGNANFGEYMAFLTTKEPFLNKIVGMYITSYTGIPFIVDHANKTVRYNAGGSYKITLP
                     TYASDPTGTMKTFAFFCVKEARTFVPKRIDLVGNVYNYFREAFPFNVKESKLFMYPYC
                     LLEITDTKGHVMTIRPEYLTGGKLSVYVKGSLGISNKVMIEPIDYDVTNSSIITNLSD
                     KMLIDNDPNDVGVKSDYAAAFMQGNKNSLIAQEQNIRNTFRHGMGNSAMSTGGAIFSA
                     LASANPFVGLTNIMGAGQQVNNYVAEKENGLNLLAGKVADIENIPDNVTQLGSNLSFT
                     MGNFQNYYQLRFKQIKYEYATRLDRYFSMYGTKSNRVATPNLQTRKAWNFIKLKEPNI
                     VGTMSNDVLTRVKQIFSAGVTLWHTNDILNYNQDNGDV"
     gene            complement(11735..13063)
                     /locus_tag="J8S10_002154"
     CDS             complement(11735..13063)
                     /locus_tag="J8S10_002154"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Other names: p8; Derived by automated computational
                     analysis using gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head protein"
                     /protein_id="HAZ9630734.1"
                     /translation="MADKITEQDVLNATNVETPVQLMTAIYNSSSSLFQANVPMPNAD
                     NIQAVGAGITRLDVVKNEFISTLVDRIGKVVIQYKSWRNPLKMFKKGNMPLGRTIEEI
                     FVDIAQEHKFNPDESVTGVFKQEIPDVKTLFHEINREGYYKQTIQEAWLEKAFTSWDN
                     FNSFVAGVMNALYTGDEVSEFEYTKLLISNYQEKELFKEIEIGEITESNAKEFIRKIK
                     STSNKLEFMSSAYNAQGVKTSTPKSDQYVIIDADTDATVDVDVLAAAFNMSKTDFVGH
                     KIVIDEFPKKQGEESSNIVAVIVDSEWFMIYDKLYKTTSLYNPEGLYWNYWLHHHQLY
                     SSSQFGNAVAFVKTATKPVTKVAFASATDTVVKGATKDIALTFTPAEATNHQGEVVSS
                     APTLVKATVKETSGKATAVTVEGLEVGQSLVTFTAIGGQQATVLVTVTSD"
     gene            complement(13076..13366)
                     /locus_tag="J8S10_002155"
     CDS             complement(13076..13366)
                     /locus_tag="J8S10_002155"
                     /inference="COORDINATES: protein motif:HMM:NF022859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630735.1"
                     /translation="MEIKEHEAILNGILESVTDGEARSKIVEHLEALREDYGATTEAL
                     TTANSTLDKLKKDNEALVISNSKLFRERANVEQPENNEPETDQNITLDDLGI"
     gene            complement(13634..13804)
                     /locus_tag="J8S10_002156"
     CDS             complement(13634..13804)
                     /locus_tag="J8S10_002156"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630736.1"
                     /translation="MDLYKAIFIVRDEGTIDGYATEHFVDISLHDFEEIYGKETREIE
                     AITLVKTGNFKK"
     gene            complement(13817..15541)
                     /locus_tag="J8S10_002157"
     CDS             complement(13817..15541)
                     /locus_tag="J8S10_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015968361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630737.1"
                     /translation="MMIKKYTGDFETTTDLNDCRVWSWGVCDIDNVDNITFGLEIDSF
                     FEWCKMQGSTDIYFHNEKFDGEFMLSWLFKNGFKWCKEAKEDRTFSTLISNMGQWYAL
                     EICWEVNYTTTKSGKTKKEKSRTIIYDSLKKYPFPVKQIAEAFNFPIKKGEIDYTKER
                     PIGYKPTKDEWEYLKNDIQIMAMALKIQFDQGLTRMTRGSDALGDYQDWVKTTYGKSR
                     FKQWFPILSLGFDKDLRKAYKGGFTWVNKVFQGKEIGDGIVFDVNSLYPSQMYVRPLP
                     YGTPLFYEGEYKPNNDYPLYIQNIKVRFRLKEGYIPTIQVKQSSLFIQNEYLDSSVNK
                     LGVDELIDLTLTNVDLELFFEHYDILEIHYTYGYMFKASCDMFKGWIDKWIEVKNTTE
                     GARKANAKGMLNSLYGKFGTNPDITGKVPYMGEDGIVRLTLGEEELRDPVYVPLASFV
                     TAWGRYTTITTAQKCFDRIIYCDTDSIHLVGTEVPEAIDHLVDPKKLGYWGHESTFQR
                     AKFIRQKTYVEEIDGELNVKCAGMPDRIKELVTFDNFEVGFSSYGKLLPKRTQGGVVL
                     VDTMFTIK"
     gene            complement(15535..16380)
                     /locus_tag="J8S10_002158"
     CDS             complement(15535..16380)
                     /locus_tag="J8S10_002158"
                     /inference="COORDINATES: protein motif:HMM:NF017271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630738.1"
                     /translation="MTVRISKNDRAKLEKIYGKSNKARKKYNRLRQKGVEERQLPTVP
                     TSKKSLIDYVKSTNMSRSDFNKLLDELVDFAQPYNENYIFEINKRNVAISRAQIKEAQ
                     IKTEQAQKAKEEHYKELNQLQIKKPTENTIVTPTILTELGADLPFQAIPDFNIDSFTS
                     PEGVQSYLENIGKQDEQYFDERDQLYYDNFRQAMFTIFNSDADDIVRLLDSMGLDLFM
                     KTYVTNFLDMNLDYIYDEAEVQQKKEQVYSKIAKVIESETGGEVPSYNPTKNITINSE
                     TGEEL"
     gene            complement(16464..16835)
                     /locus_tag="J8S10_002159"
     CDS             complement(16464..16835)
                     /locus_tag="J8S10_002159"
                     /inference="COORDINATES: protein motif:HMM:NF037548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630739.1"
                     /translation="MEIVKSTFDSQTPEGMLQVFNATNGASIPLRNAIGEVLELKDIL
                     VYSDEVSGFGGAEPSQAELVAFFTEDGKTYAGVSAVATKSAKNLIDMMSANPDIKPKI
                     SFVEGKSNGGQKFVNLQVVSL"
     gene            complement(16874..17140)
                     /locus_tag="J8S10_002160"
     CDS             complement(16874..17140)
                     /locus_tag="J8S10_002160"
                     /inference="COORDINATES: protein motif:HMM:NF037583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630740.1"
                     /translation="MSRKLMQRNVTSTKVEFSEVIVQDGAPTIVPCESVVLTGKLSEE
                     KALSAIKRKNPDKNVVVTNVSHETALYTMPVDKFIELADKSTQA"
     gene            complement(17262..17534)
                     /locus_tag="J8S10_002161"
     CDS             complement(17262..17534)
                     /locus_tag="J8S10_002161"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630741.1"
                     /translation="MKYSLEQIDEIRSTILRIKLKRDELEELLDELNDIAKDPEERYV
                     LSFYYTREERLFEIPSVRLIDYYNTKIINLKSEIISLEKRLQKLVK"
     gene            complement(17534..17815)
                     /locus_tag="J8S10_002162"
     CDS             complement(17534..17815)
                     /locus_tag="J8S10_002162"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630742.1"
                     /translation="MKTSYKQLDELISLKNRMKHNKTHLKYITECIDEVKKSSGDPYR
                     IKVSYDNHYLTLVSITKEQVINNLEKEKLKLTTAILEIQDEIIEILEEK"
     gene            complement(17812..18102)
                     /locus_tag="J8S10_002163"
     CDS             complement(17812..18102)
                     /locus_tag="J8S10_002163"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630743.1"
                     /translation="MKLTDATNYMSELSSNLETIDNLIKDLNSSYNMNDQVRVYLEKD
                     DVTLDYWAKSKSFNVSFEKEIIISALKDQRKVLYTELIKTKEFISELLEEKQ"
BASE COUNT         5347 a         3412 c         2828 g         6588 t
ORIGIN      
        1 gaaaggatca taaaaacaat caaataaatc attaaataaa tgaattaaat gattgacata
       61 tatgtaaatg catgatatac tatagatgta ataaagaaag gatcataaaa acaatcaaat
      121 aaatcattaa ataaatgaat taaatgattg acatatatgt agatacatga tataatatag
      181 atgtaataaa gaaaggatga tcaaaatgta ttttgatatt ttaattgaat tatacgacgg
      241 cgacatagaa aaaacaagct tattcacgga tacagataaa ttaaaaactt acctttataa
      301 tattttagac aaggaggacg ccgaattttt attagaaaac ggaaaggtag ttattgatga
      361 ttacacgttg tatcttgata gcgcaatata ttaatttaat acaatgctac caatcacatt
      421 ttgattggtg gtatcaatat caaattaata taaaaggagt gtttcatatg tttaacaaag
      481 cattaatagc tgaaaaagga gaggtatctc tacttcgccc ttttaatgtc tgggatatga
      541 attatcatat catagatacc gaaaacaata agcattatcg tatagatatc gatgatgtag
      601 gcgatgagga atattgtttg ttatcttttg aagagttaaa ggaattagat atggatctta
      661 tttccgaata ttcatggaaa actacaaaaa taactgatta atttaataca atgctaccaa
      721 tcacattttg attggtggta tcaatatcaa attaatataa aaggagtgtt ttacatgatt
      781 aacaatttat cattaatttt agagggttta aatcaactaa ctaaagagga caacgatagt
      841 ttagcgtcta tcaagtcaga aataacacaa ggaggaaacc aagtaatttt atacattgat
      901 tacgttacaa aagagttcgt gttaacacat gataaatata actatgttta tcttgatagt
      961 cattgcatta atatcgcaat aacgaaatca atgaaaagcg ttgaacacta tgcggaacaa
     1021 ttgaaacatg acggatataa acaaattacg gataaatggg agtgattaaa atgattgcac
     1081 gaacattcaa agaacatcgc gaacttattg aatggttacg tttctactgc aaacgtaacc
     1141 attcagacaa tgaaaaaata gagatcatag agggtacttt acaagatttc gacgttccgg
     1201 aaataaatat caccgagctt tttttaactc attcgacact attgcccgaa tcaagtcaat
     1261 ttaacatact tgaaaagtat tgtcaggcaa tgaacctagt aacttcatac gtaaaagttg
     1321 gttctcgcta tcagttagcg ttacaaatac caaaaggata tttaaaggag aaagaactat
     1381 gagaaaagat ttcgtctaca ttaacacacc tgatccaaaa gcagacaaaa aggcgttagc
     1441 aagaatcacc aacgccaaag aaccaaaaca aaactatcga agattacaat tactatgtta
     1501 tctactattc atcattgtaa tagagttatt attggtagcc ttactaaaat agggctacca
     1561 tattttcata cgattaaaca aatcataatg taagttctta ataacaatat tatcaaacct
     1621 taaataacta ttcttaaagg ctttcgccac tgttgaaaga taataattat tccgccaatt
     1681 tttcatcaac aatctgtttt cctcatggtc ttttgtagtc attgcataaa aatggtttgt
     1741 atttggttga taatcataac tcacatatac acaacccgtt tccgcgtcta tccaataacc
     1801 aaatattttc ccttcaaaag caattgcaca caagaaactg ctattcttac ttctcttttc
     1861 aataaatgta tcactatcat taacaaattc attgttgata ctaaaatctt cataatctgt
     1921 accacgtatt aaccttccga aaggtgtttg tttctttact tctgcaaagt cttttgaatc
     1981 acacaattca atcaaaattc ctcgatcctg atatagatta aaacgcttat tcaaatctgg
     2041 ctgtagattg aaatacaaga aataagggtt gactacactc gttgcattac tcaacagaat
     2101 acatctagta tttgtgcggt cacgaaaaac agtttccatc atatttaaca aggcttctgc
     2161 ttcatttggt aagtaggtaa tttttgattt ctcgatcaaa aactcatcaa acaaaattgt
     2221 acgaacatct ggatattcat tagatttttc aataccccat gtactaagcg gaacggccca
     2281 acccattaat ttatcatcgc aataaaactc tttcccttta acttcaagtt tatgttcggg
     2341 aaattctttc gccattgtct tgaaaaactg aggaatcttt ttaagttctg ttttgaatct
     2401 tcttaaataa ataaattgtt cgccatgttt tataaaacga ttaacaacaa attttttata
     2461 tccatacgtt ttacctatac cacgtgcgcc tattacaaac aacattaggc aattgaaacc
     2521 taaagcattg ttaggactat agtataagtt tttctcttta agtttaacgc ctaagctatt
     2581 tgtcatacta tacactccta tttatacact ggtttcttat catacatttt taaataaata
     2641 tcaaactgtt caggcgtcca caccattgat ggaatttctt ttccatgtac atgattgtac
     2701 gttccacgaa tatgatcgag ttgcgttgga tcagacaatt caaagatcgt gtttccatca
     2761 aaataaaaca cgcttgtact accctttgtc aatgtgaaaa tgaactcatc acttgtagca
     2821 tcaaatattt tattttcagg agcaacaatt tggtctgatt ttttaccaac atacaaatcc
     2881 catgtttttt gatctccata aaatacattt aaatcaaggt ttccattata gcccgataaa
     2941 cgaccgctac tcgtatattg aaagcaagca acaattggaa aattatttgt tttaggtggc
     3001 gctggttgag agtagccttg tggtaaattc ctaccatatt ccgcaatcca caaaccataa
     3061 tcgccttttg caatactaga aaaatcagtt gtattgaggt ttgctgtata cgtgtaaaac
     3121 catggtttaa tacctgtttg attgtacaca taatcaagaa acgctttcgc ccatgctgaa
     3181 tctttttggt ttgaaccttc aaagtcaaga attagaattg ctttaccaat gtaaccttga
     3241 atattcttta agaaaaatgc tccttcttgt tctggtgtac cttctaagcc tttctcatgt
     3301 gcaaagtggt acacaccaat ctttttacct aaagccaaag cttgttgaaa tgctcgatca
     3361 caatcaggat tgacatagcc tgtaccacct gttgctttaa tatttacaaa gtcacatgga
     3421 acttttgaaa gatcaatccc tgtttgatga ctagaaatat caataccatt catcatttaa
     3481 tatcgtcctt tctgttgatt gttccgtcta aaaacttctt aacataatca gtccaattgt
     3541 tattatcgtc tatagttgaa atgtgtccta gtatactata aatttctgat aaaattaaac
     3601 caaccaacat tgttacatac attgtaatac ctactgcacc gaattttact gctacaggaa
     3661 taaagtaaac cactaaaatc atttctgcca ccttaacaat aattcctgct ttagctttaa
     3721 aactactaaa gtcgatttcc ttgtcaaatt tggcaattgt aaaacctaac acaaaatcaa
     3781 taatcatcgc aaccattagc cacaaaatta aaccgtaaat catatggtta tcatctgcta
     3841 accatgttgt aatatattct atcataccat tttttctcct tattaaaatt tccagccatt
     3901 taatgaatca gatagccaca aataaataag atcatcttta cctttattgt tgtcgtcatt
     3961 atctccatcg ccaaaacatt ggcctaaaaa ttttagaggg tcttcccacg ttccatcatc
     4021 aacaaaagat gagcctaacg ctgtcataaa gtcttttttt gtgaacccta agtgtaaatg
     4081 atctgcgtca cgtatagcac acacttgacc attcttaact ctatcgccaa cttttacttt
     4141 tatatttgac tgattataac taaactcttg ataaacgata ttgtaagtac catcatttat
     4201 cacgaaatac gctcttaatg cgcccattgt tccaacatgt gttactgtgc catcgcaaca
     4261 agcaatcatt tcattaccag gatgatcgat tgaaccaaag tccaaaccat catggaaatt
     4321 gtttggtctg ccatttcctg cgtgtgtacc aaaaagctgt ccactcatga aactactagg
     4381 atcgagattt gtgttcttga tcggtgttcc atagcaacgt tttacgccac cgccaccgct
     4441 accatcaata tgtttactat aagcttgtgc aagatcaagt ctttcttcaa tatgaagctt
     4501 gcctggtctt tcccaatgac acataaaatt gattgtagca acatcaatat ttgtggattg
     4561 cttaaatgcc gagagggtct gaggattagt atatcctgga taagaaatag gtgtattatc
     4621 catccattga cctgttttat ctccttgagc gatgatctct gcttgaccct ccaacgtttc
     4681 agcttgagca ttagacaatc cacaaatttg agcttggcga taaagattgc ttttaggcgt
     4741 ccattgacct aagccataac caccgccacc gtattcattg gcgttcgggt tcaatccagc
     4801 cgattcccaa tggagattag cgacaactcc tacttgtgaa tttttattat agccatgttt
     4861 accaagtatt ttagcaattg tttgtcctct agctatttgt tcatttgtaa gagttgccat
     4921 ctcatatccc cctagttata tacgttactt gcatttggtc ctgttagtac atgatcaatt
     4981 ttacgattat agaaaacagt ctgaggtgct ttatagatca tcggggtatt tacttttgtt
     5041 gaattagaca atccacgaac aataaaccca tcataattaa cacgcttatc tgctgtttga
     5101 ataaagcggt aaccatctgt caaaggtgct tcttgtgcca ttagatcaca atagaaatta
     5161 acgccaccgc catataaagt gataacatgt ccttgacaac gatataactt tcctgtaatc
     5221 cttaagtttc ggtaatgtcc gtaaacaaca actaaacgtg aaatagctgt actattcatt
     5281 ccttcaactt gagagttacg agaataaaca tctacatcaa tataagcttg atccacatct
     5341 tgaaattcaa acaaggcgtt tctatttcca tatgctagaa aatggttgtt gttttgaaca
     5401 tgcaagttat gtgcatatcc tcgataataa cttacgccac cttcgatcgt attactagaa
     5461 atttcacaga aattaattac attctgataa tcatcttcgt tatcaataat gatcgctgta
     5521 caaaagtgaa tacgattgtg tttcacaaaa aatcctctaa atcctgtgcc tctagtatta
     5581 atatcgttcc cttgccacat actgtttaca tcgggaaaag ctgttttgat gattgcttga
     5641 gagatattag agaatagaca attttgaaag gtaacccctc tacctctagc aacaacaaca
     5701 tatgttcctt catttaaagt acagttgcga acaaacaaat caaagtcaaa acggttgtaa
     5761 tttcgagtat cattaaagaa aattccttta ccactttgag cgccttgtgg caaccataat
     5821 gcaaaaccat caatgttgaa actttcgatg tttacattaa atgccgtcat tgtttcaaac
     5881 tttaatgttg tttctcctga tcctaagaaa gtcactactg gaacatcacg ctttaattca
     5941 atcgtgttag caaagcgata atatgaatca cgttcacaag gtggaaaata aaaagtgata
     6001 cccatttcgc ttttttcttc aagtagttta tttaaaatag gtgtgcaatc ggtcacgccg
     6061 tcagcaacaa ccccataagc acttacatcg attgtagttg tcatttttct tttgtcaaca
     6121 aatttgttga aactctcctg attttcattc tcatgtaatg gttcgtcaaa aacaacttgt
     6181 ttcgggttcg tttcagggtg caatacgtaa ttcttttgat tttcttcttt catcttgttc
     6241 atttgaatat caatacgttt ttccatatga acctccttat tttagaggga aaacacaatt
     6301 atctaaggat agatactcga ttttacctac attctcattt acacttactc ttccgtctgt
     6361 cataatcgta acataaatga tttctttcgt gttagttgga tttggtgtaa aatatttacc
     6421 catgcaacca atacgttttg tcctcaatgg tctaaagcct tctggtaacg ttgtaatcac
     6481 agggtttgtc aaactttcag taaactttac cataccttcg atcataccaa ttgctccgag
     6541 ataagagatt gcatttgttt tatcactagc tgtatatagt tcacaatttg tcatggtcaa
     6601 ttcagcacga cgagtcaaat ctaacaagtt ttctgctcga acacttggat ataaattatt
     6661 ctcattgcta tccttcattt gaatattttt atttgccatt atttttcctc ctatggtaat
     6721 acactatatt gtattgttgt gttctctaaa ctgcttactc gaacagcaag atcagttgca
     6781 gtttgttttg ctgaatcagc tgtgttttta gctgtcgttg caactgaact ggcactgttc
     6841 gctgttgttt tcgcttgttc tgcggtttgt tgtgctgtac cacccttcgt caacgcttga
     6901 tttgcggttg atgttgctgt tgcaatctct gttgacaaac catcagcagt tgttttagct
     6961 tgttgtgcaa gggttttagc ttcactagcg ttacctttta tttcagcatt aactaattca
     7021 agattagagt cgtctattag aacattttta gcaatggtta caggcattaa acgattttga
     7081 tctttatcct tcatttgaat atttttatct gccatgtttt tcctcctatg ataaaacagt
     7141 atattgtatt gttgtgttct ctaaactgct tactcgaaca gcaagatcag ttgcagtttt
     7201 ttgcggtgaa tcacctgtgt ttttagctgc catattacac ctctacataa cgaataccat
     7261 caagattagc cactgtactc tctaatgttg ttattcgatt ggttagtttg ccaacattta
     7321 catttaattc acttacagca tcctttgctt gattggcagt aactactgca ttttgaactg
     7381 acgtattcat tgtttcgtta ttttgtttga gtgtacctaa ttctccttct acattcgtgc
     7441 cgctattagt cataatatta acggcttttg aaactggaaa taaattgtct gttccatctt
     7501 cacttgttag ttgtgttcta atgtctgcca ttatacagcc tccgttcctt taatgttaag
     7561 ataaatatct cctgtagcgg tattccatcc actaacttta ttgattgcaa cgattctcat
     7621 agtgtcaata ggatcatctc cataatcggt atcatcgcgt tgaatcttat accaaaatgt
     7681 tcgatcatca gcaacatcgg gtttattttt tgccaaaaga atattcacac tgttagcacg
     7741 tgtttcagca accaagattt gtaatctttt gatttctttg atataatttg caaaaacagt
     7801 gtcgttgatt aaattttcta acgtaccatc agacaaccat tttttgagtg tgtcagttgt
     7861 gatctcctct aacttctcaa caaaatgttc gataaagtaa tttaaataac cactcatatc
     7921 attaactaaa gcgccaacct cattcagata ggcaattaaa gccgatactt cttcatctaa
     7981 tagtaattcg tatctgtatt ccgtatgagg gtatttgcta aaccgttctt tgaatactga
     8041 gggtaaaccg tcaaaccgct tgtcgtggtt aaaatctatc attgttacta cctccctcca
     8101 taaacaagga gaaataagcc ttccttgttc atttctctaa agatcatttt ctcaattctc
     8161 aaaacacttc tacgatattt ttcgagtaag tcagcataat cagtgtttcc ttttttacct
     8221 ttatatcgtg taatcgtatc tttggtttga ttttgatctt tattaatatc tgtattcttt
     8281 gtttcttttt cagaagcatt gcttcgtgta ttttggtttg ttttatcgtt gtttgtttca
     8341 acgccggtgg agcttgttgt ttctttactc aaatcttctg taatatttgt tgcataattg
     8401 attacacctg taccatttcc attgctggca attctcaaat ctttttgagg agtgtctgta
     8461 tacgtgtttc ttgagaaaga atcggttgtt cctgtgtcac gggtattttt gtttctgttg
     8521 tctgtttgat cgacttgttt cgtttgattt tttgactcat cccgattcgc tttgatgttt
     8581 gtatcaatct catttaacaa tttctgtttc tcatcaatgg tatagtccat gtcatcaaaa
     8641 atcggaaact cttcaagatt tgataggaac atcttattcc aatagggcat atttagattt
     8701 aaatactcgt caagattaaa cttaaatgat cccatcgttt ctgatcctat ctctctcaag
     8761 taaaagtgat tgataaattt tgtttcaaat tctgctcgtt ttgtttcgtc ataaaatgga
     8821 taatcaaaat caaacagttg ttttctgcca acttcaatac gttcttttcg agataattca
     8881 ggttggtaat aagtgaaact ttcaatataa cgtttaagta gcactaggca accctccact
     8941 catctgatct tttttcgatt gacctgccgc tagttgtaat tgtcgcaccg cgtccgttct
     9001 aaacttcacg tcaatctttc cgtcaagttc atcgccaaag acacgattta cacgatcaca
     9061 aaactctttt cttgatttta acaagatgtt tcctgagctt tcaatctgtt cgttgttaga
     9121 taagacttct gatgtttgta cacgtgcagt cttatctacg ttggcattgt tgatacctag
     9181 aaaagttaag acttcattcc atacttcgtt caattctgat cttagtttat ccactacata
     9241 tggtgcattt gtttgccaca cattaaaagc ttggtcaaac tccatatctt tatccacaaa
     9301 aacagcctga ttattttcgt caatttggtt ataagcttgt agcaatgaga agtatttctt
     9361 ttcatcagtt tgaataatta caggtgtttt ttgcgctctt cgattcactc gtgatatctg
     9421 gtttatgtct gccatatcca aagcaaaccg atgaagactc ggtagtgtag gaactttcaa
     9481 gtcattgtta tacaacatga tacattttga tttatcatca tcatcatcat atcttaaaac
     9541 aggatatctc ttgtgataca ttgcttcatt ggctgtaaag aaaataggat tgtgataatg
     9601 atcgatttga ccatcttctg ctcctgcaca aaccatgaag cctagtgtag ggtctttaaa
     9661 gaaaccgaga tacccatttg tgtgtaatgc aatttctaaa tatcgagggt caattgattt
     9721 cggtaaattt tcccattcaa acaactgaaa cgtaaggagc gtgagttgtc tacgataatg
     9781 ttcatagtag ctgatttctt ctacatcact tgaatagggt tcgtttggat aaggtctgct
     9841 ttttgctgta taacggttat ttctagcaag tcctgcacct tttcgtctac tcatcttatt
     9901 cctccttcct acacatctcc gttgtcttgg ttataattta aaatatcgtt tgtatgccaa
     9961 agggtaactc ctgcactaaa aatttgtttc actcttgtta aaacatcgtt actcattgta
    10021 cctacaatat ttggttcttt taatttaatg aaattccatg cttttcttgt ttgtaagttt
    10081 ggtgtagcta ctcgattgct ctttgtgcca tacattgaga agtaacgatc caatcttgta
    10141 gcgtactcat atttaatttg tttgaatcgc aattgataat aattttgaaa gtttcccatt
    10201 gtgaaagata agtttgatcc tagctgtgtg acattatctg ggatattttc gatatctgct
    10261 actttacctg ccaaaagatt taatccattt tctttttcag caacatagtt gtttacttgt
    10321 tgtccagccc ccataatgtt agtcaaacca acaaatggat tggcgctggc taatgcggaa
    10381 aagatcgccc ctcctgtact cattgcactg tttcccatac catgcctaaa ggtgtttcgt
    10441 atgttttgtt cttgagcaat caaggagttt ttgttccctt gcatgaatgc agcagcatag
    10501 tcagatttaa ctcctacatc attaggatca ttatcgatta acatcttgtc acttaaatta
    10561 gtaataatgc ttgagttagt tacatcataa tcaattggtt caatcatgac tttattagaa
    10621 atgcctaacg aaccttttac atatacactc aatttaccac ctgtaagata ttcgggtctg
    10681 atagtcataa catgtccttt agtatctgta atttctagta aacaataggg atacataaat
    10741 agttttgatt ccttaacatt aaatggaaaa gcttctctaa agtagttata cacgttccct
    10801 accagatcaa ttcttttagg aacaaatgtt cttgcctctt tcacacaaaa gaaagcgaat
    10861 gttttcattg ttcctgttgg atcactggca taggttggga gtgtaatctt atacgaacct
    10921 cctgcattat accttactgt tttgttagca tgatccacaa taaatggtat acctgtatat
    10981 gacgttatat acatcccgac tatcttattt aaaaaaggtt ctttcgttgt aagaaacgcc
    11041 atgtactctc caaagttagc attacctgca ccatttggtt tgtatacctc gccacttgaa
    11101 ttgagaggaa gtaaataata ggaataaggt gacggccctc cgacaattga tcctcctgat
    11161 ttatcttcct tatctcctac tggcattgct tcacttgtta gaataacaag aaaattgact
    11221 ccatcgttag gatgaaaagt tgttacattt gttgttgtgt attctctacc gtaatcaagc
    11281 gactcttcaa tcgtattaat gaatggtact ccattcgaat aataaagttg tggatgttct
    11341 ttcgcaatga aactttctcg tatgccaata tcgaaacgat aagtttgtaa aacatcaatt
    11401 tcaaaagtaa cgaaacttgt gttgtcgttc ttatattcaa tatctgtaac aaaggcatac
    11461 tgccatttac taggataagt ttcttcgttt ttaaagatga gatagttaca agcatataaa
    11521 gcgtctttgt gtttatctac tctaaaaact ccaccgagtt gtgtatctct ttgataagaa
    11581 caatcagtat tctcgttcag aacaggaaac gaattaaaat acgattcctg ttcctgttga
    11641 gttttacacc atcttgtgtg tgcataggtg ttatcaaaag gcacgttagc caacaatttt
    11701 acatgtgtat accgtcttgc cataattgtc ctccttaatc agaagtaacc gtaacaagaa
    11761 ccgttgcttg ttgacctccg atagctgtga atgttactaa tgattgaccg acttctaacc
    11821 cttctacggt tacggctgtc gctttgcctg atgtttcttt gactgttgct ttaaccaatg
    11881 ttggtgctga tgaaacaact tctccttggt gatttgtagc ttcagctggt gtaaatgtaa
    11941 gtgcaatatc tttagttgct cctttaacaa cagtatctgt tgcacttgcg aaagcaactt
    12001 ttgtaactgg tttagttgct gttttgacaa aagcaacggc attcccgaat tgggaactag
    12061 aatataattg gtggtggtgt aaccagtaat tccaatataa gccttctgga ttgtatagac
    12121 ttgttgtttt gtacaatttg tcatagatca taaaccattc actatctaca ataactgcca
    12181 caatatttga cgattcttcg ccttgttttt taggaaactc atcaataacg attttgtgtc
    12241 ctacaaagtc agttttactc atattgaatg ctgctgctaa aacatcaacg tcaactgttg
    12301 cgtcagtgtc agcgtcaata ataacgtatt ggtcagattt tggtgtagat gttttaacgc
    12361 cttgagcgtt gtaagcagaa ctcatgaatt ccaatttgtt agatgttgat ttgatcttac
    12421 gaataaattc ttttgcattt gattcagtaa tttcaccaat ttcgatctct ttgaataact
    12481 ctttttcttg gtagtttgaa attaacaatt tcgtgtattc aaattcactt acttcatcgc
    12541 ctgtgtataa agcgttcatt acaccagcaa caaaactatt gaaattatcc catgaagtaa
    12601 atgctttttc taaccatgct tcttgaatcg tttgtttgta gtaaccttca cgattaattt
    12661 cgtggaacaa tgtttttaca tcgggaattt cttgtttaaa tacacctgta acagattcgt
    12721 caggattgaa cttatgttcc tgtgcaatgt caacaaaaat ttcttcgatc gttcgaccta
    12781 aaggcatgtt tcctttttta aacattttca aagggtttcg ccatgatttg tattgaataa
    12841 ctactttacc aatacgatca actaaagttg aaataaattc attttttact acatctaaac
    12901 gtgtgatccc agcgccaacc gcttgaatgt tatctgcatt tggcataggt acgttcgctt
    12961 gaaaaagaga tgatgaacta ttataaatag ccgtcatcaa ttgtacaggt gtttctacat
    13021 ttgtggcgtt aagaacatct tgttctgtaa ttttatctgc catgtttttt cctccttaaa
    13081 ttcctagatc atctagtgta atattctggt ctgtttctgg ttcgttattt tctggttgtt
    13141 ctacgttcgc tcgttctcgg aacaattttg agtttgaaat aaccaacgct tcgttatctt
    13201 tctttagctt atcaagtgtg ctattcgctg ttgtcaaagc ttctgttgtt gctccgtaat
    13261 cttctcgcaa tgcttcaaga tgttctacaa tctttgatct tgcttccccg tctgtgacac
    13321 tttcaagaat accatttaaa atggcttcat gttctttaat ttccataatc tccacctcct
    13381 tttgattcta ttataccata aaaactgttt cacgtgaaac ataaatctgt gaaacacaaa
    13441 aaaagagtag ccgcatttaa gggctactcc taaaaggttt ttgcgattgg ttaacggtca
    13501 aaacgtttat gtgtccataa cttaacggga gcgcacgatc tctcacgtgt acattcgccc
    13561 aatctcgcca aatttgactc ttgttaacta tcacaagaat attttaccat actttgcaaa
    13621 ggatgtaaat aatttatttt ttgaaatttc ctgtttttac taatgttatt gcttcaattt
    13681 cacgtgtttc ttttccgtag atttcttcaa agtcatgcaa agaaatatct acaaagtgtt
    13741 cggtagcgta accgtcaatc gttccttcat cacgtacaat aaaaattgct ttatataggt
    13801 ccattattag tcctccttat ttgattgtaa acattgtgtc tactaatacc acgccacctt
    13861 gtgttctttt cggcagcaac tttccatagc ttgaaaaacc aacttcaaaa ttgtcaaaag
    13921 ttacaagctc ttttattcga tctggcatac cagcgcactt tacatttaat tcgccatcaa
    13981 tttcttctac gtatgttttc tggcgaatga attttgctcg ttgaaatgta ctttcatgcc
    14041 cccaataacc aagtttttta ggatcaacca agtgatcgat tgcttctgga acttctgttc
    14101 ctactagatg aatgctatct gtatcacaat aaataatgcg atcaaaacat ttttgagcgg
    14161 ttgtaatggt agtatatcta ccccaagccg tcacaaaact agcaagcgga acataaacag
    14221 gatctcttaa ttcttcttct cctagtgtca atcgaacaat gccgtcctcg cccatgtaag
    14281 gcacttttcc tgtaatgtca gggtttgttc cgaactttcc atacaagcta tttaacatac
    14341 ctttagcatt cgcttttcta gctccttcag tggtgttctt tacttcgatc catttatcga
    14401 tccagccttt gaacatatca caagaagctt tgaacatata accatacgtg taatgtatct
    14461 ctaaaatgtc gtaatgttca aagaacaact caagatcaac gtttgtaagt gtaagatcaa
    14521 ttaattcatc gactccaagt ttgtttacgc tcgaatcaag atattcgttt tgaataaata
    14581 atgagctttg cttaacttga atggttggaa tataaccctc ctttaaacga aaccttactt
    14641 tgatattttg aatgtaaagt ggatagtcgt tgttcggttt gtattctccc tcatagaata
    14701 gaggtgttcc atatggtaaa ggtcttacat acatttgaga gggatacaaa gagttaacat
    14761 caaagacaat gccatcgcct atttctttcc cttgaaaaac tttgtttacc caagtgaagc
    14821 cgcctttgta tgctttacgt aagtctttat caaaccctaa agacaaaata ggaaaccatt
    14881 gtttaaatct tgatttacca tatgtggtct ttacccaatc ttggtaatcg cctaaagcgt
    14941 cacttcctct agtcattcga gttagtcctt gatcgaattg aatttttaat gccattgcca
    15001 taatctgaat gtcgttcttt aaatactccc actcatcttt tgtcggtttg taaccaatag
    15061 gtctttcttt tgtataatct atttcgcctt tttttatagg aaaattaaaa gcttctgcaa
    15121 tttgtttgac tggaaaagga tattttttaa ggctatcata aattattgtt cgagatttct
    15181 cttttttcgt tttacctgat tttgttgttg tgtaattaac ttcccaacaa atttccaaag
    15241 cataccattg acccatattt gagatgagtg tggagaatgt tcgatcttct tttgcttctt
    15301 tacaccattt gaaaccgttt ttgaataacc atgaaagcat aaactctccg tcaaattttt
    15361 cgttgtggaa ataaatgtct gtgctgcctt gcattttgca ccactcaaaa aaagaatcga
    15421 tttctaagcc gaacgttata ttgtcaacat tgtctatatc gcatacgccc cacgaccata
    15481 cacgacaatc gttgagatca gttgttgttt caaagtcgcc tgtatatttc ttaatcataa
    15541 ttcttctcct gtttctgaat taattgtgat gttcttcgtg gggttatatg aggggacttc
    15601 tccacctgtt tcagattcga tcacttttgc aatcttactg taaacttgtt cttttttctg
    15661 ttgtacttct gcttcatcat aaatgtagtc aaggttcatg tctaagaagt tagtaacata
    15721 ggttttcata aataggtcaa gccccattga atcaagtaaa cgaacaatgt cgtcagcatc
    15781 tgaattgaaa atagtaaaca ttgcttgcct gaaattgtca taataaagct gatctctctc
    15841 gtcaaaatat tgttcgtctt gttttcctat attttctaaa taagactgaa ctccttctgg
    15901 agaagtaaaa gaatcaatat taaaatctgg tattgcttga aaaggtaagt ccgcacctaa
    15961 ctctgttaaa atcgttggtg tgacaattgt gttttctgtt ggtttcttaa tctgaagctg
    16021 gttaagctct ttgtagtgtt cttcttttgc tttttgagct tgctctgttt taatttgagc
    16081 ttctttgatt tgcgctcttg agatagcaac atttcgcttg ttgatctcaa aaatgtaatt
    16141 ctcgttgtaa ggttgtgcaa agtctaccaa ctcatctaat aatttgttga aatcactacg
    16201 actcatattt gttgatttta cgtagtcaat aaggcttttc tttgatgttg gaacagttgg
    16261 tagttgtctt tcctcaactc ctttttgtct taaacgattg tactttttac gagctttgtt
    16321 agattttcca taaattttct ctaacttcgc tctatcgttc tttgatattc ttactgtcaa
    16381 ttctacacac ctcaatgtag aatcataata aaaaccacct agcgagattc gctaagtggt
    16441 ttactagatt cctgtatttt atgctacagt gaaaccactt gtagatttac aaatttttgt
    16501 ccaccgtttg attttccttc tacaaaagaa atttttggtt tgatgtcagg gttagcactc
    16561 atcatatcaa ttagattttt agctgatttt gttgctactg ctgatacacc tgcataagtt
    16621 ttaccatctt ctgtgaagaa agcgactagc tctgcttgtg atggttcggc tccaccaaag
    16681 ccagaaactt cgtctgagta aactagaatg tctttcaatt ctaaaacttc tccgattgcg
    16741 ttacgtaacg gaattgaagc tccgtttgtg gcattgaata cttgtaacat tccttctggt
    16801 gtttggctgt caaatgtgct ttttacgatt tccatgattc taatctcctc tgttttcttt
    16861 tagttttgtt ttattaggct tgtgttgatt tgtctgctaa ctcgataaat ttatcgactg
    16921 gcattgtgta aagcgctgtt tcatgtgaaa catttgttac tactacgttt ttatcagggt
    16981 ttttacgttt gatcgctgat aaagcttttt cttctgaaag ttttcctgtt agtacaactg
    17041 attcgcatgg tacaattgta ggtgctccat cttgtacgat aacttctgaa aattccactt
    17101 tagttgatgt cacgtttcgt tgcattagtt ttcgactcat tcttttccct ccttttgtaa
    17161 tttgataaga atgattgagg tgtgaagtaa ggtattttcc gttcccttac taccctttta
    17221 gtataacatg atgtgttata tttgtaaagg tttttgtgta attattttac tagtttttgt
    17281 aatctttttt cgagtgatat gatttccgat ttcagattta tgatctttgt gttgtaataa
    17341 tctattaatc ttactgacgg aatttcaaac agacgttctt ctcttgtgta ataaaacgat
    17401 aaaacatatc tttcttccgg atctttagca atatcgttta attcgtccaa cagttcctcc
    17461 agttcatccc tttttaattt aattctgaga attgttgatc taatctcatc tatttgttct
    17521 agtgagtatt tcattatttc tcctccaaaa tttctataat ttcatcttgt atttctaaaa
    17581 tcgctgttgt taattttaac ttttcttttt ctaaattatt tattacttgt tcttttgtga
    17641 tagaaacaag tgtaagataa tgattgtcgt acgaaacttt aatacggtat ggatcgcccg
    17701 atgatttttt aacttcatct atacattcgg taatgtattt aagatgtgtt ttattgtgtt
    17761 tcatacgatt ttttaatgaa attagttcat ctaattgttt ataacttgtt ttcattgttt
    17821 ttcctccaat agttctgaga taaattcttt cgtctttatt aattctgtgt ataatacttt
    17881 tctttgatct tttaaagctg aaattatgat ttctttttca aacgaaacat taaaagattt
    17941 tgattttgcc caataatcga gagtgacatc atctttttcc aagtaaacac gaacttgatc
    18001 attcatattg tatgaagaat taagatcttt aattaaatta tcaattgttt ctaagtttga
    18061 tgatagttct gacatataat ttgtagcatc tgtaagtttc attttattca ccccccttta
    18121 ccttacaaat atagtttacc atataatcac atatttgtaa aggatataat agata
//
LOCUS       DADQDV010000059        17918 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.061, whole genome shotgun sequence.
ACCESSION   DADQDV010000059 DADQDV010000000
VERSION     DADQDV010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17918)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17918)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17918
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.061"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(14..1140)
                     /locus_tag="J8S10_002164"
     CDS             complement(join(14..912,912..1140))
                     /locus_tag="J8S10_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAZ9630744.1"
                     /translation="MTRYEENFKQMIVELNQTGRSVRGLAKEYGLSEATIYKWKNLYL
                     PDQSTGLTGKEVAELRKENARLNEELEILKKAGSHILSENLNSLVQFIEKWCKDYTVS
                     LLCRLLEIPRSVYYFYKNKPLTATEIRNNKLKKKISTIFFTNKQRYGATKIHQVLLKE
                     GISVSLKHVQKLMKQLNLRSIVVKKYRPQRSNKPIISKENLLNQDFSTETICEKWAAD
                     ITYIPTKKNGWCYLSSIMDLHTKKIISYTFSKRMTVDCVIQTLNKAKIHYHIPEGMIL
                     HTDLGSQYTAREVEQWLKTNKIRHSYSRKGTPYDNAGIESFHASLKKEEVYTTSYSDF
                     EEANRALFSYIEGFYNRNRIHSSIHYLTPQEFEELAKEKMA"
     gene            complement(1198..1635)
                     /locus_tag="J8S10_002165"
     CDS             complement(1198..1635)
                     /locus_tag="J8S10_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAZ9630745.1"
                     /translation="MYVEKLYEMILIVKYRVEVLFMVTRIFILDDSLVFEKMLVEILE
                     ESRILLSPWKFEIVQGLNVIQFVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLRE
                     KNEKCKIVYLTSHPNKAITVINRKITPSGYLIKEFTYGVSIKS"
     gene            complement(1820..2656)
                     /locus_tag="J8S10_002166"
     CDS             complement(1820..2656)
                     /locus_tag="J8S10_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HAZ9630746.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            complement(2667..3596)
                     /locus_tag="J8S10_002167"
     CDS             complement(2667..3596)
                     /locus_tag="J8S10_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HAZ9630747.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            3788..4141
                     /locus_tag="J8S10_002168"
     CDS             3788..4141
                     /locus_tag="J8S10_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HAZ9630748.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            complement(4215..4871)
                     /locus_tag="J8S10_002169"
     CDS             complement(4215..4871)
                     /locus_tag="J8S10_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HAZ9630749.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            5097..7031
                     /locus_tag="J8S10_002170"
     CDS             5097..7031
                     /locus_tag="J8S10_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAZ9630750.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            complement(7117..8340)
                     /locus_tag="J8S10_002171"
     CDS             complement(7117..8340)
                     /locus_tag="J8S10_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronyl hydrolase"
                     /protein_id="HAZ9630751.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(8334..10232)
                     /locus_tag="J8S10_002172"
     CDS             complement(8334..10232)
                     /locus_tag="J8S10_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HAZ9630752.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            complement(10226..11344)
                     /locus_tag="J8S10_002173"
     CDS             complement(10226..11344)
                     /locus_tag="J8S10_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 88"
                     /protein_id="HAZ9630753.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            complement(11427..12260)
                     /locus_tag="J8S10_002174"
     CDS             complement(11427..12260)
                     /locus_tag="J8S10_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAZ9630754.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            complement(12253..13170)
                     /locus_tag="J8S10_002175"
     CDS             complement(12253..13170)
                     /locus_tag="J8S10_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAZ9630755.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            complement(13397..14521)
                     /locus_tag="J8S10_002176"
     CDS             complement(13397..14521)
                     /locus_tag="J8S10_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAZ9630756.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            14704..15612
                     /locus_tag="J8S10_002177"
     CDS             14704..15612
                     /locus_tag="J8S10_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAZ9630757.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            15753..17366
                     /locus_tag="J8S10_002178"
     CDS             15753..17366
                     /locus_tag="J8S10_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-disulfide reductase"
                     /protein_id="HAZ9630758.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
BASE COUNT         5632 a         3472 c         2960 g         5854 t
ORIGIN      
        1 ttagtagaga cggttaagcc attttttctt ttgctaattc ttcaaattcc tgtggggtta
       61 gatagtgaat cgagctatgg attcgatttc ggttataaaa tccttcaatg tagctaaata
      121 gcgctcgatt tgcttcttca aaatctgagt agctagtcgt gtagacttct tcttttttca
      181 atgaggcatg gaaagattcg attccagcat tatcataagg tgttcctttt ctactataag
      241 aatgccttat tttgttggtt ttaagccatt gttccacttc tcttgctgtg tattggctgc
      301 ccaagtcagt gtgtagaatc attccttctg gaatgtgata atgtattttt gctttattca
      361 atgtttgaat gacacaatcc acagtcattc gttttgaaaa tgtataacta ataatttttt
      421 tcgtgtgtaa atccatgatt gaagataagt aacaccaacc atttttctta gtaggaatgt
      481 acgtaatgtc agctgcccat ttctcacaga tcgtttcagt agaaaagtcc tgatttaaga
      541 gattctcttt tgaaatgatc ggtttattag acctttgagg tctatatttt ttaactacaa
      601 tcgaccttaa atttaattgt ttcattagct tttggacatg tttaagagat actgaaatcc
      661 cttcttttaa taaaacttga tggatctttg tggcaccata gcgttgttta ttcgtaaaaa
      721 aaattgttga aatcttcttt ttcaacttat tatttctgat ttctgtagct gtcaacggtt
      781 tattcttata aaaataatag acacttctag ggatttctaa taaccgacat aacaaagaaa
      841 cagtgtaatc cttacaccat ttttcaataa attgaacaag cgaatttagg ttttccgaga
      901 gaatatggct gcggcttttt ttaagatttc aagttcctca tttaaacgag cattttcttt
      961 tctcagttca gctacttctt ttccagtcag tcctgtggac tgatcaggta aatataaatt
     1021 cttccatttg taaatcgttg cttcagataa gccatattct ttcgctaacc ctcgaacaga
     1081 acgtccagtt tgattcagtt caacaatcat ttgtttaaaa ttttcttcat atcgggtcat
     1141 aaaaattcat cctctcgtag ataagtttaa tttattcttg tctctacgaa aagctgtcta
     1201 agatttgata ctaacaccat aagtgaattc ttttatcaaa taaccactag gcgtaatctt
     1261 tcgattaata acagttattg ctttattcgg atgagacgtt agataaacaa ttttacactt
     1321 ttcattcttt tctctaagca tttcgcctag ttcgataccg ctataatagg cgttcaaatc
     1381 gatgtctagg aaaaaaatat ctgaggaata gatttcatta tttttaatga attcaacaaa
     1441 ttgtataacg ttcaatccct gaacgatctc aaatttccaa ggacttaata aaattctgga
     1501 ttcttccaaa atttctacta gcattttttc aaaaaccaaa ctatcatcca aaataaatat
     1561 acgcgttacc ataaaaagta cctccactcg atattttact atcaaaatca tttcatacaa
     1621 cttttcaaca tacatgttag gaataaattg taattctctt cacaatcttt tccaacacct
     1681 ttgaaaccga tatcaaatac tttcaggatg ctgcttctaa aataaatatc aaacaaatga
     1741 atacatcatg caaaaaaagc cagacaaccg acgtccttgc gtgtcagctg tctgagctat
     1801 gtttatttat tttgttcttt taaaaagaac gatacacata ctgatttttc ggagcagaga
     1861 ctttctcagc gtttgtaaca actacagatg ggatttcacg cttgaatggt tgataatagt
     1921 ctgattggat ggttccttct attttatacc attcatcatt tttaaccgtt actccttccg
     1981 gcatatgcgt caacaaacca aagactcctg aatctgccac acaatggata atgccgaatc
     2041 ggaacaagaa gatatctgta ttgctatcgt tcggtgtttg gtaaacaaat ccttcatagc
     2101 tgattttttt gccaatgaat tcgctagggt aattataaat tagctccata acttctaaat
     2161 agttttcatc tgtgatcttg atagtttgct tatccccata cttttctttc aactcattca
     2221 tttggtctaa gtagtctgat ttgttgaaat aaatactggt atccggcttt aagtattgtg
     2281 tctgcatctc cggatcccct actgattctt tacttactgg gaaattaaat cctttggctt
     2341 ctacgatcgt agtgtcgaga ctaactgttg gaaacaacgt ccccacgatt actggcaaag
     2401 ctagcagtac ataagcgatt ccacgttgat aaggttttga caacccatgg tcatgatcgt
     2461 gctcgtgtgc cttttcttct gcttttccgt ttttgaccca caaatacagc tgaactaaag
     2521 ccaaaagagc agataaaatc attgaaagaa tagctaagta gcgataatgg acattgatat
     2581 attgatcgag tttgccagaa acttgcaagt acatcatcaa ttcgaaatac ccagataaaa
     2641 tcaaaaaccg cagcatattt tccctcctaa ataaataatg tgaatccaat aacgctaagg
     2701 gcaatcagtc cgatcagcga taaaataaag cgtcctgtaa aatatcgttt catcatcagt
     2761 agatttttga tatcgaccat tgggccaaag accaaaaagg cagctacagg tgctgtgccg
     2821 aacagactta acaaagaaga tcctataaac gcatctgctt ctgagcaaag agacatcgta
     2881 aaggccaata acagcatgat gataatggct aaaatctttg ttgagccgag cgttagcata
     2941 attctagttg gtaaataagt ctgcatcgca gctgcgatta atccgccaat gatcaaataa
     3001 cgacctgtat caaaaaattc gtcgattgaa tgtgtcaaca catgcccagt ttgatggatc
     3061 agctgatttt ttggttcatt cttctcactt tgttcttctt catggacatg atgatggtga
     3121 ttttctgcta ctttagacgt gattttttct ttcaatacag cgtctttttg aaaataggca
     3181 agccagacac caatcacaag ggcaacaaaa aagctgccta tcacccgcca gcttgccatc
     3241 tgccaagaat tgccaaatgc gataaaagtg gaaaaaatca cgattggatt gatgatcgga
     3301 gcagtcagca taaaagcaaa cgctgtgtga actggtacgc cttttttaac aaattgatga
     3361 acgatcggta cgatgccgca ttcacatgaa ggaaagaaaa atcctaagat cgaaccagta
     3421 aaaatagaga agatacgatt ttcaggaagc catctcttca cacgttctgg ggtcaaaaat
     3481 acttgtaagg cgcctgagat aagacagcct aataatacga aaggtaatgc ttcaataacg
     3541 atcgataaga aaatcgtact catctgcaaa accgaatttg gaataaaaga aaacatgagt
     3601 ttcctccttt ttatttctag ttcattcgct ttgcaaatat acgcttttat tcaaaaaaaa
     3661 caagttgctc tgtaaatttt tacacaactc ttatttttta ccaaagcact tcaattgact
     3721 ttttctgtta ttcccattaa attaaggtct catacatatc acttctatca taaaagggag
     3781 aataaaaatg aaacaaacca ctaacttgac tgaagttcaa gacatactgc aacagtcatc
     3841 cgttgccgtc atttatcttt cgatgcctaa ttgcagtgtt tgtcacgctg ttcgtccacg
     3901 actagaggaa cttctcacac attatgatat tccggcactt catttggatg catttgaaac
     3961 accagaagta gctagtaaat ttgaagtgct gactgcgcca gttgtcctga tttttcatca
     4021 aggaaaagaa gtctttcggc aagcacggtt catcgacttt aaaaaaatcc gttatctact
     4081 agatgaactg acagcagaag atgattccct ttcttatgaa gaaatcttcc gaacaaaata
     4141 atcgttgtcc aaacagaaaa aagcgattga acaagtgaaa gttttgcctt catttgttca
     4201 atcgcttttt atttttattc tgctgtattt tcggaatgcg catttgcgtc agaatgcaag
     4261 aaatagatca aggtttgcaa ttcattcgtc aaatcaacat tttggatcaa tacatctgac
     4321 ggagcattca atcgagcagc ggtaaagttc aagattcctt tgattcctgc ttccgttaac
     4381 tgattgacta cttcttgtgc tctttcagcg ggtatcgtta aaattgctac ttcgatttgt
     4441 tggatcttga tttgttctga catatcttcc attggataaa cggggatacc gtctacgatg
     4501 cgcccaacga tttcctcatt cacatcaaaa gcacaactga tacgtatgct attactttga
     4561 tggaatttgt attttagtaa agcacttccc aagttcccta caccgatcag cgcaacattt
     4621 gtcaattgat cgtcgtttaa tgtctttgca aaaaagtgca taagatcttc tacatcataa
     4681 ccatacccac gttttcctaa ttcgccaaaa taagaaaaat ctcgacggat cgttgcacta
     4741 tctacttgaa cggcttcact taattcagtt gaagacactt ttttctttcc agcattattt
     4801 aaaatcctta aatagcgata atacaaaggc agtcttttag ctgtcgcctt tggaataata
     4861 tgatctttca cgaaatgacc tccacgtatt gtctaattac atctttgatt tctccatcat
     4921 agcagtattt ataggaaaaa atcaattcca ttgctcagat attgtgaaat tttattcttt
     4981 attcatttat ttatcatttc tgcaaatctc gcagtataat ggaatttatg gtagactact
     5041 aattgaaaaa tagtttttta tttgaggaga attcacaaag tagaaaagag gattccatga
     5101 tattattaca agccaatcag attgctcgcc attttggtgc agaagtctta tttgaaaaca
     5161 tacatttaga aatcagtaca ggcgctcgtg tcgctttagt tggcagaaat ggcgctggaa
     5221 aatcgacttt attaaagatc attgctggaa ttgaagcacc tgatgaagga aagatcgcta
     5281 aaaataaaac agcgactctc ggatacctcg ctcaggacac aggacttgat tccaatgaaa
     5341 cagtttggaa cgagatgctg aaagcttttg aacaagttag acaaatggaa gagcggatgc
     5401 gcgagctaga gattttcatt agcgaaggta cgccagacac acctgcttat agttcttatt
     5461 taaaagaata cgaccggctg caacacgatt tttcagatcg aaacggctat ggttatgaaa
     5521 atgaaattcg ttccgtattg catgggttta aattcgattc ttcattttat gatcagaaaa
     5581 tcgatacttt atcaggcgga cagcgcacac gtttagcttt agctcgcatg cttttgcaac
     5641 accctgacat tttgattcta gatgaaccaa cgaaccattt agatatcgag acactttcct
     5701 ggcttgagaa ttatctgcaa agctatactg gtgcattatt gattgtttcc catgaccgtt
     5761 attttttaga taaagtagtc aatgaagtct atgaattaag cagaagaaaa atgcgccatt
     5821 acaaaggtaa ctattcgaaa tatctagatt tgaaagcaga acagttagca agtgaatgga
     5881 aggcttatga aaagcagcaa acagaaatcc ataaattaga agacttcgtt gctcggaacc
     5941 ttgttcgcgc ctctaccaca aaacgagcgc aaagccgcag aaagacatta gaaaaaatgg
     6001 accggctgga tcgtcctcaa ggggatgaaa aacaagcaaa ctttctattc agtatagaaa
     6061 agccttctgg aaatgtagtc ttgcaaatcg aagatgccgc tatcggatat gataatgtca
     6121 ccttatctga accaatcaat ctagatatcc gtcgtcaaga agcgattgct ctagtaggtc
     6181 cgaatggtat cgggaaatcg acgttgctga aatcaatcat tcaccagatc ccttttatcc
     6241 gtggaaaaga aacgctaggg acaaatgtca ccatcggcta ttacgatcaa ggtcaagctg
     6301 atctgcatac aaacaagacg atcctagcag aattgtggga tgagcatcct accactccag
     6361 aaaaagagat ccgaagtgct ttaggtgctt tcttattttc tggcgaagat gtagaaaaac
     6421 caatccctct gctaagtggc ggtgaaaaag cacgggttgc tttagccaag ttagcgatga
     6481 acaaagaaaa ttttttgatt ttggatgaac caacaaacca tttagatatt gacaacaaag
     6541 aagtattaga aaatgcattg atcgattatg acggcacact gctttttgtt tcccatgacc
     6601 gatatttcat caatcggatc gcgacaaaag tcgtcgaact ctctgaaaat ggcagcaaag
     6661 tctatctagg agactatgat tattatttag agaaaaagca ggaagaagaa gaaatcgccg
     6721 aattgttggc acaagatgag ccagaatctg ctcctgctcc cacgaacaaa tctgattatt
     6781 accaaagcaa agaacagcaa aagcttatcc gtagccttca acgaaaaatt actcaggttg
     6841 aagaagaaat ggcgcggatc gatgaatgga tcgatcagtt ggaacaagaa atggtcgcgc
     6901 cagaaaacct ggaagatcac gtaaaactca atgagctgaa ccaagattta gaagctgcta
     6961 gacaagatca agaaacaaaa ttgacggaat gggaagaact aagcttggaa ttagaagaat
     7021 atgaaaatta acgaaaaaac caaaacagaa accattcatg ctgttttggt ttttcttttt
     7081 ttattttatc aaacaaaaat tccatattta cctttttcac caataagaag accaattact
     7141 agtcattctc actaaagctt ctaaataata gtaatcaccc caaatacaag gtgtatttac
     7201 cccattattt ttgggcttat tataaacaga ctgtgttaaa aagccatctt cttcttccgt
     7261 tgtagcatat ctttctttca attgtcgcat aattttccaa acagcagact ggtataagtt
     7321 cttttctgtt ttgtctaata gacctgattc tattaattct aataatccac aaaccatgat
     7381 caccatacta gatgtatctt tttcttctct gctagaatca tcaaagatca aatcccaata
     7441 acaaatggta tcttctggca accgattcat aaaataattg gctaatattt tgcttaaatc
     7501 aaaatatttt tgttctttca aataacgata acttaatgca aaaccgtaaa tcccccatgc
     7561 ttggcctcta gcccaacagg aattatcact ataaccttga tgcgtacttc catatcttgg
     7621 ttttccatct ttgacatcca tataaaatgt atgataagtt gaaccatctt ctcttactaa
     7681 ataatctgct gcattttgaa tatgagcctg agcagctttt ttatattttt gatttccagt
     7741 ttcttcactc gcccaataca ataatggaag attcatgcaa caatccatga tcattctacc
     7801 ttgttgtgaa ggatcactag gatctcccca agcttgtata actcctgcct tctcccaaaa
     7861 acgctgaagt aatgtttctg cagcatcaat tgaagcttcc ttcatttttc gatttcccgt
     7921 tattttataa tctgctacgg ttgataaaga atacaaaaaa ccaagatcgt gatgattagt
     7981 gataatttga cagtcaatcc tgtggataaa atctatatct gctttttcag ctgtttgttg
     8041 aaataaagga tcacccgtct tctcaaataa caaccaatta attcctgtcc aaaatccttc
     8101 tgtccaacca atattgtctc ttaatggata acgtcctttt ataggacact cgcttgggaa
     8161 ttgatactga ctgttactga tacgtttgat taacctctcc gtgtgtctgc gacaacgctc
     8221 gatctcatta ttccattctt tttccattaa ttctttataa cattcattta tccatttttc
     8281 tggatgtatt atctcttcaa acatcacttt atcaagcatt tccccaccag cctttagcat
     8341 aattttagtc tttttttatt gtttttattt tggatagtta gcccggttgt cccatcaaaa
     8401 tcaattttgg gacgattgtt ccatacttct aaactataat cccgatcttg atgagcaacc
     8461 actcctgttc cgagccaatg ggttcctttt ccaaatgtac cctctaatcc aggaataaaa
     8521 gtgttttccc atgtcatcaa gtttgtattg ggcaaaccca taatagctgt ggattttcgt
     8581 ttaatagtat cgtcacttaa acagataata cctgaaaagc cagcttcact caccctatag
     8641 ttttccttgt cttcttctat gattattcct tctttctcag gagaacattc aatagcaaac
     8701 cctgtctcat atagaacata ttctgtatct aattctactt tgtgtacgcg aatctgccag
     8761 ccttcaaaag gaataagcca agttctgatt tttgcctgta aagtaggttc ccatgtagag
     8821 gcaagtacct ctttcttaca tacaatgtct cgtacattat ttcgaacgat gaactgtcca
     8881 taggttttga tgctctcatt cttaaaactg gtcgtgatat atgtgtccgc tcgctgaatc
     8941 cctagcattg aatccattgc catttctgct ttcaattgat tcgctcgcgg tatcgaaaaa
     9001 ccaaattgac tagaataagc aaattttaaa tatttttcat tggtcaatgt atggaaattt
     9061 ggccctaatt gtcccgcatt caaaaaaaat gtatgtccat tatcatgttg tatgagcaaa
     9121 ttggcttctg aaagaagttt agttccttca cgaataggca taggcatttc tttagccgtc
     9181 caatactcat ggtcttcagg tagcgccaac aataaaaaaa tcttattcag ccataatgga
     9241 gataacgtac tattataggg ttcagtcaat gtcaattgag ggtaggtata accaatattc
     9301 aggatacctt tttcatcaaa tatttctttt tgcatccacc atcttatatt ccgattgact
     9361 aaccccttga tttcacctaa tttaaaaggc aaaagatcgg cccacaacat agctgaccaa
     9421 aagcttgaaa ctgcaaaacg ataaatcatg cttcgaccaa aaggcacatt tgcaccatct
     9481 tccgcaaaaa aatgaatata gtctctagaa aaatcaatag ctcggttctt atatatctgg
     9541 ctaatgggct tttctggttc tagtacgcta taaatcaaac cataataatg aaatgcaaaa
     9601 ggattataat aatcttggcg acctcttgaa ctgtctcgat accagccatt ttgaagataa
     9661 caattttcta tattatcaaa tgcttctttc agtgctgatt ctttaactgg ataaccaaat
     9721 ttttggataa ttgttccgac aattatctta aaaaattgcc aattaccatc tgcacattca
     9781 tattcaaaaa tttgcgagaa ccaatgaata atctggcttt tttctcctgt atctaatttt
     9841 ttccataata attgttcatg atgatataac gctaataaca ttgcgggcat ttctaccata
     9901 cgctggtctc tttcatgtat ttctccccaa taatcgggat gggaaggatc tgttccagct
     9961 tttattcctg atagaattaa tttcaaccat cgttcatcta attggtcaat tgcgggcccc
    10021 gctccccata aaacccgaga gaatccttcc attcctgcaa ttttatttcc atatcctacc
    10081 ccttgatgta tataatcaat ttgtgcgcca cttgctcgat aaaacggctg gagtggttga
    10141 tttatctttt taaataagtc aaagtaatcc tgtctggtcc ttaatagtgg tactggatgt
    10201 ttcattgtat tttctcctct ttttactacc aaatagctaa ttccgactgt tctaatcgaa
    10261 gtaagccttc aataaaaaaa taatcagaat agatcagtgg cacattataa gtcagttctc
    10321 tatggtatgc ttctgctccg cctccaatga tcccatcttc atccatattc caatttgcat
    10381 agtgcttttc tgtcttttgg agtatattga tagcagcttc atgatacatt tttgatcgta
    10441 cagaggaaac atatcctgct aattccagaa gaccgcatgc agcgcatact ccagcactgg
    10501 tatcaatatt cgaatctttt acagcaaaat caatgagagg aatataacca gttttttcga
    10561 ttttctgaat aaaatttact gctatctttt ctgctatagc tagatagtac ggattttttg
    10621 tgtaacgata acttaacgcg aatccatata aagcccatgc atttcctctg ctccaacaag
    10681 aattctcatt gtatccttgc ccgccaagta accgaatata tttccctgat tctgcatcaa
    10741 attctgcgat atgcccggtt gatccatctt tcctcactag atacttagct gttgtatctg
    10801 catgctgccg agcaatttta gagaacctcg gatcaccagt ttccctcgaa gcccaataca
    10861 gtaatggtaa attcatcata ctatcaataa tcatccaacc aggtttatgg tcattccatg
    10921 ctactaaata gttccctgaa atattatagc gtccagcaag taccgtagct gcatgtaacc
    10981 ctagttgtcg actatgtttg ttttgagact gttgataatg tgcaatagcc gatggtaaga
    11041 ataaaaaacc tacatcatga tgaacgtctg aaaaatggta cagggcagat tctaataatt
    11101 gttcttgttg tattgctgcc tctttgaact tttctcgttt tgtcttgtga aagagctgcc
    11161 ataaaatacc actccaaaaa ccattggtcc accagtcgat tcctctgtcc tttattacgt
    11221 ctgtatattt tccgttgtaa gaaatatatg gaattttatt ccccattctg tctaattccg
    11281 catctatctt ttcagaagct acattcaaaa tttttcttga ccattccttc gtctgttcat
    11341 tcatggatat cccgccattc ttttaatttt tatgaatgtg gagttgctcc tagaacgaac
    11401 tagatggtta acattcgtta ttttttttac ttatttgcag ctccaatgtc attctcctta
    11461 aatttagact gcgcccacac ataaatcaag accattggga tcactgaagt tgctaaaatt
    11521 agcataattg cgccataatt aattggctca cctgtactag aaaccgtcat atttttgata
    11581 attaagggaa ccgtatattt atctttatct gaaagcatga ctaatggaaa tagatattga
    11641 ttccaacttc ccataaagat aagtaaacca ctagtaataa tcgtaggtga taaaatcggt
    11701 acagcgattt tcgtaaaaat cacccactca ttggcaccat cgattctggc agcctccatc
    11761 agtgctgtag gaaattgact gctatattgt cgcatcataa acactgaagt tgtactggca
    11821 atcgaaggga tgatcacacc tgcataagta ttcgataatc ctaaacgact cataatgtaa
    11881 aataaaggaa tcaatgtggt aaaaaaaggc accatcctag atagcataac tgtattgaac
    11941 aacagtttat tccccataaa acgatacttt gctaatgcat aacccgccat tgtagaactg
    12001 gctgtagcta aaactgtact gattacagca ataacaatcg aattccaaat aatcaaggga
    12061 taattatatc tcgccatgat ggcttgccag ttttttaata gcatatcccc aaacttgaaa
    12121 ttgattccgc cacttaaaat ttcttgatta ctttgcgttg aagctacaat catatataaa
    12181 tatggcatca aaaatattaa ggcaccaaac acaataatga cgtacgtaaa aattctgctt
    12241 tgtatctttt gtttagtcat ttttatcacc tccgaattta aattgaatag ccgataatat
    12301 aacagataca aacaccatcg tccaggcaat agcagaggct tttccaaaat caaccatttc
    12361 aaaacttgtt ttatataaat tgactcctac gaccaaagct gaattttctg gtccattgga
    12421 agtcccaaag aatatatttg ggatattgaa attacccaag ccattgatag tggctaaaac
    12481 tgtggccatt aaaatgattg gctttagcat ggggatcgtt aataaaaaga attgccgaaa
    12541 tttcgatgct ccatctattt cagcactttc gtatatctct ttagaaatcc cttgaagacc
    12601 agctaaaaat aaaatagtgt tatatcctac actaagccaa atcatcgtga tgatcattga
    12661 tattcgtatc caaaaaggat ttgttaacca ctgtacaccg ttaattccta gcgcattcaa
    12721 aaatccattg aataacccag tcggattgaa aaaagtcatg aatacggaag ctacagccac
    12781 cgttgatgta atggttggaa tataatagac agttctaaaa aatccttttc cttttaactg
    12841 tgctgaattc aataaaacag caaagtaaat agctaatagc atcgttattg gaattgatcc
    12901 tgccatgata atcaaaacat tcgtgtaaga tttaataaac aatggatctc ggaagatagc
    12961 tagataattg tcaaatccaa caaattcaaa tgagtagcca attttcataa aactaaaagc
    13021 aaacgagata atgatgggaa tcaaaatcgt cacaataaag aaaataacaa aaggtgtgac
    13081 caatccataa gcactttttt tatgagacgt atctgttgct tttttcttgc tgttctttat
    13141 tgtcttgctt ggtaacgaag attgcatcat cgttaagtcc tcctaatatt ttttaatcac
    13201 cagttaattt tacgccgtac ttatgagcaa aattttctgc ttcttttaga tatgaatttt
    13261 caaaatcacc tgtttgccaa tagttatatg cagcggtagt caaataagac gtagcatctg
    13321 aataagtggc tggtaaaaca gtatttgatg tattttcatt gattttattc aatagttcat
    13381 agtatttttg tcctccttag tagtcaaact ttttctcagc tgcttctgtt tgataggcca
    13441 atgagttaga tgtagccacg cccagctcca gtgcgttggc taagcattct tcatctgtca
    13501 gcataaatgt aagaaattgt tgtgccactt gtggattttt tgcatcttta gggacataaa
    13561 aacttgatcc tcctgatact gcaccttttc ctggattttc ttttgaaaaa ggaatcagtg
    13621 gagccatgcg ccatttgtca gatgcatcag gaaaattcaa agacatattc gtagcatacc
    13681 agccgccagc aacaaacatt gcagattctt gaaatgcttt ctcagcatct tgtgcaccgt
    13741 agaaatgtac aatatctgag tcgatcattt ctttgattaa ctttgcagca tgtttcgctt
    13801 ctttagtatt cagacggata tttccttctt catcaagcaa agattgattc tgctgggcta
    13861 gcatgttgat aaacaattct tggtccccag attctggcaa ggcaattcca aaactaccag
    13921 ttttttcttt taatgctttt gccacctgga tatattcttc ccaagaactg atttcttcaa
    13981 aatctacacc tatttcagca aatttttttg gttgataata acaaagtgct ggggtaaaat
    14041 cactagccca aggaataatc gtttcattac tcgtttgttg acgcaaaata ttcaattttt
    14101 gatcataaaa ctgatcgcca tatttgtcat aaaatccata ttcatcagca ctataaaaag
    14161 catcttgaaa tttttccagc acacctgctg ctgaagtgtc tgccatggag ataatatccg
    14221 gcatatcttc gtgtgttacc aattttgggg tgatcatttg tactgttgct gttcccgaag
    14281 ctacattcac aatttttaag tcaatatttg ctccagtttt gcggttatag atttttgcag
    14341 cattttcaac atagtttgtc agtttgccgt ttgcgacata tacttctaat gtagtggctt
    14401 tttttatcat tggatctgcg atgtttgctg ttacttcttc gttagttttt ccacatgcac
    14461 ttaagctgaa taatagggta atgtttagca aagctatcac caatttgtat ctttttttca
    14521 tgtctatccc ttctttcttt tcaagttctt atataaaacg ctttcactta tgtatattaa
    14581 cggaattagt aacacaaata tttatataaa aaaatatttt acttgtcgtt ttggcttttc
    14641 atttttgtta taatagtcat taattataaa tagaaagctt tttatataaa aagagaaagg
    14701 aaagtggttc ttttgttaac aaacaaccaa tcctccaatc ttgtcaaaaa aacactaacc
    14761 tattccatag atacccatct tcatttatct gctgctccct attttcgact actaataaat
    14821 gaaagcgcta atttatatgc tgaatttgca cataaatcta tagaactaga taatccttcc
    14881 cttttattca ttgataaaca gcaagaagtc caaatctttt ctactcaaaa ggaaacacaa
    14941 acttttatca ttatccagtt ttattttgat gagcaattat tagcacatat tacgggacaa
    15001 tctttttcta tagatcaaga aataacatct atcattactt ttctgaaaaa tgaacagttc
    15061 aaaattgatt atctaaaaca tagtaagcca gctatttcct atgatcagga aatcaattct
    15121 tttttcatac tatgccaaca gatgagcatt catttgcttt ccttattagt tacttattgt
    15181 ctgcaaaaaa ttcaattgtc ttccttacca aggcattatc aacaggaact tgctttattg
    15241 acaatacctt caaatgagaa agtcattcct aaaaaaaagc atattcttta ttcagatgaa
    15301 ttagttgatc caatcatacg atatttagaa gaacatcttt cagaaaattt tttgcttgaa
    15361 caattagccc aaattttttt tatcagtcca gccagcttaa aaaaacattt tagaaaagtg
    15421 aatggaaaaa gtgttattag ctattttaaa gaactaaaaa tggaaaaagc aaaacgtctc
    15481 gtgctagaaa atgaattaac ctatacagaa attgcagata tattaggatt tcattcgatc
    15541 catcattttt cttcagcttt taaaaaatat acagggttat ccccttcaaa gtattatcta
    15601 tccttaaaat agaaaaaaat ttttaggttt tatccacaaa ttatttctct atattttctg
    15661 tctattcaaa ataaacaata attttccggc acaattattt gctgtttttt accataacat
    15721 agtacgatca acgtagaaaa ggagatgttt ttatgaaagt tgttgtcatt ggcggtgtag
    15781 ctggcggtcc ttcatttgcc actcgtttcc gtcgattgaa tgaagcgcac gaaatcatta
    15841 tctatgaacg cggagaaaat atttcttatg caagttgtgc tttgccttat tatttaggag
    15901 gtgtgatcac tgaccgtgac tcgctgatcg aacgtacacc agaaatattg aaaacaaaaa
    15961 acaacatcga tgtctttact aaacacgaag taacagcaat cgatccttct actaagcgat
    16021 taacagttaa agacctatcc acaaatgaag aaataaaaac agattacgat aagttgatca
    16081 tctcttctgg tgctagacca gattatccgg atattcccgg agtttttgaa gcagaaaacg
    16141 gctttgtcct ccgtagtgtg acggatgcgg atcgaatcaa atcgttcctt gaagaaaaaa
    16201 atccacaaca tgtcgtcatt cttggtgcag gtgttatggg tctggaatta gctgagaatt
    16261 tcaagcatcg cggcttagac gtgactttaa tcgatcaatt gccacaagtc gctttccctt
    16321 atgatccaga aattgctaat ttagtttatg acaaattgct gaaagaagga ttagccgttc
    16381 atttagaaac aagagttact gagatccgtg ataaaggtcg agaaatagta ttatcagatg
    16441 gctccgtcct ttctgctgat atgctaattt ttgctgttgg tgtttctccg aagaatgaag
    16501 tggtgaaagc aaccggcata caattatcag atacaggtca gatcattgtt gatgaccagt
    16561 tacaaaccaa tctgccggac atctatgcga ttggcgatat tatcgaaacg actagtgtag
    16621 tgactggtca gccgatccaa agtatgcttt ccagtgcggc caatcgtcaa ggacatatgc
    16681 tggcagatat tttaaatggt acgcctatgc gctatcgcgg atatattggt gcaggtgtcg
    16741 caaaaatctt tgatcataca gcaagttatg cgggaatgac agaacatgaa ttaaaagcat
    16801 caggcataac aaattataaa actgttttta tcactccctt tgaccatgcc tatttctatc
    16861 cagaagctac aagattaaat ctaaagctga tttttgatgc agatagcggt cgtattttag
    16921 gtggacaagc atttggagaa aaaggtgtcg ataaacggat gggagaactt tctgtagcaa
    16981 tcaccggaaa cttgacagtc tttgatttgc ctgatttgga gttgccttac tctccaccgt
    17041 attctactac ccgtgacccg ttgaatatag ctggttatgt cgcaatcaat caaatgacga
    17101 atatcgtaga aacgatcaaa gcaagtgata tacccgaaaa cgatttgaaa gaagcgttct
    17161 ttttagatat acgtgaacct aataaagcac cttctggcag tatctcggca acaaaaaata
    17221 ttccaatgaa tgagttacga gatcgaatca atgaaatccc aaaagataaa aaagtttaca
    17281 ttactttcag aagaggattg aatacttata cttctgcccg aatcttggca ggtttgggta
    17341 tcaaagcgat tttgattgaa gaataaaaaa acgaccgcgg tgggtagccg cggtctagga
    17401 gttattttta cttgaggagt aaaaatgaaa aagtatatag ggttgttggt tggtatgtat
    17461 atagaataga agataaatgt gaagaaattg tgcattattt cttcacattt attaggttat
    17521 agtttaagaa agtttaaaca ttgcgcaatt taattatttt agctgtttct tttcataaaa
    17581 aaacatgttg tgactctgag acaaatcata gtccatagtg atgtctctag agtaactacg
    17641 cctaatatta cgaggcatca tattaatcta tcagcactag tacctaaact agcatccctt
    17701 tcgaatattt tttcttatat aataaagttt gctttcactc ctctaatctc accaaatcga
    17761 ctggcttgcg ttgtgtgata ctaggaactg attggtttag aacgactttt ctattgtaat
    17821 catatttttc gccatcctcg ttgtcttcta atccttcaat gaatgatccc taatgtgtgt
    17881 attaaataat ttaatttttt tgttcctatt tatttaac
//
LOCUS       DADQDV010000060        17375 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.062, whole genome shotgun sequence.
ACCESSION   DADQDV010000060 DADQDV010000000
VERSION     DADQDV010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17375)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17375)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17375
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.062"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(72..617)
                     /locus_tag="J8S10_002179"
     CDS             complement(72..617)
                     /locus_tag="J8S10_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAZ9630759.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDSVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(629..1321)
                     /locus_tag="J8S10_002180"
     CDS             complement(629..1321)
                     /locus_tag="J8S10_002180"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HAZ9630760.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(1340..1624)
                     /locus_tag="J8S10_002181"
     CDS             complement(1340..1624)
                     /locus_tag="J8S10_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630761.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(1637..2200)
                     /locus_tag="J8S10_002182"
     CDS             complement(1637..2200)
                     /locus_tag="J8S10_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HAZ9630762.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            2428..3090
                     /locus_tag="J8S10_002183"
     CDS             2428..3090
                     /locus_tag="J8S10_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     protein"
                     /protein_id="HAZ9630763.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            3214..4410
                     /locus_tag="J8S10_002184"
     CDS             3214..4410
                     /locus_tag="J8S10_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HAZ9630764.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(4511..5887)
                     /locus_tag="J8S10_002185"
     CDS             complement(4511..5887)
                     /locus_tag="J8S10_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAZ9630765.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGTILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(5924..6790)
                     /locus_tag="J8S10_002186"
     CDS             complement(5924..6790)
                     /locus_tag="J8S10_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
                     /protein_id="HAZ9630766.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(6879..7904)
                     /locus_tag="J8S10_002187"
     CDS             complement(6879..7904)
                     /locus_tag="J8S10_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAZ9630767.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(7922..8596)
                     /locus_tag="J8S10_002188"
     CDS             complement(7922..8596)
                     /locus_tag="J8S10_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAZ9630768.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(8780..9673)
                     /locus_tag="J8S10_002189"
     CDS             complement(8780..9673)
                     /locus_tag="J8S10_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAZ9630769.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(9747..11444)
                     /locus_tag="J8S10_002190"
     CDS             complement(9747..11444)
                     /locus_tag="J8S10_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAZ9630770.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(11437..12750)
                     /locus_tag="J8S10_002191"
     CDS             complement(11437..12750)
                     /locus_tag="J8S10_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAZ9630771.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(12750..16787)
                     /locus_tag="J8S10_002192"
     CDS             complement(12750..16787)
                     /locus_tag="J8S10_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HAZ9630772.1"
                     /translation="MVVDERIDNQELQENETDTEDSAEIQRSEENEMEKLDEPIVPSG
                     QALQRIQRQLFNGILERLGPTATQDPYEYIYPSGEVENEQHRYPKFTTNDYTKVLGNW
                     TQSNERYQGDKGSPYDGENLIDDSDYTNGGANWRNYDYATNNGSTAGEEDRNVPAQTV
                     QLWGNERNFENSYLDYNGAYIKKWVEPVLPSSTASDLHPEDATTLYNVYLDVIGGEKK
                     EISPIDIVFVLDKSASMSELTAGTNSQTKNAALIEAVNEMSKDLLSDPSLDIRIGMVN
                     FYHNSTAINNHEQISSDIFPLTNDINRLTGSENTALNRTPIGGTPLTLGLKNGYETLY
                     KDNGGENRNPEKILIVVGDGTPTFSYAPIQSSYRTSTNGAWSNWTVMEDKIAEDNDVL
                     FRNFEEFSGNTSNAGFTHPVTYASDFNRPEDEVNVHYRYGEVKEGDNKATHWVGDGSS
                     NNNTNGSPTSQEKSSAINTVAYHHWLKNKYQENPPSIFSIGLGIDGNVSGRQRLDAIG
                     RNVLKNIADLEEDGVTPRYYNANNKNDIVTALEDISSTFKRTIQQATLYDETGFNVSP
                     FGAGRSADIQFYHLDPGENGMKYQEPEIWDEERHGQAPPEVVATPTTYVGRENQAYKF
                     SPISLGEGEMVRIKYQVKLDAGAQDGNFCTVNNMAYIQNLEDYENDITTGRMYFPSSS
                     IRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQNPESGEAEPIETSKTTTDGIAIFETK
                     MPILGDETGAVSDIFWIREIAGPPRYQLVDETYQFQIKKYAANEDEMLGHYELVDEYT
                     SGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNIEGTEYDELYVKLEMRNEFKPIHMNIN
                     KLIEGSNMPINGAEFELYETDGNGLEIGYPVAKGLSGVNEVEEEKGRLTFYSVDEDGK
                     YVIVDGEKVIHPIGEPDSFVYKDSEETTNYAEYKIIESQNPEGFKEPDENDTWILRLY
                     DNAIGTIQLKQTGEENWQYLTYTTDEEDRLWVAFTAYNTFDYREIRVRKLDHEGHTLD
                     GAGFDIRKVGDSSFPLYRAYTGNPLEPEESKRLPGIGYFYSRAVGVEKYVDLNYDQPL
                     HLSIGEYEVSESVAPNGYRLSDQVFQFALNEEGKFIIEDTVIEDETAPLPEGYEIIDG
                     VLQVTLEDELAPIDLELLKIDSMNSRRLEGAEFSIEKQNSAGEYEIIEGGLAPDPNDS
                     SLFNASDLLEGVYRIKEVKSPDSYRKLPGYFILEISYREEPDIENDRVVPGKEAGTLK
                     VEISYYPNEEAETPDLQQELEYELLETNRIRLQLSVGNDPENPLPATGGSGRLFYILL
                     AAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(16800..17258)
                     /locus_tag="J8S10_002193"
     CDS             complement(16800..17258)
                     /locus_tag="J8S10_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAZ9630773.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
BASE COUNT         4865 a         3901 c         3017 g         5592 t
ORIGIN      
        1 acaaagtcgt ttgttttatg ctcttctttt attattttgt gctttttatt ttatcaaatc
       61 actttgtttt tttataaaat ttctgcgcct agtgtggact caaaatgtct caatgcccat
      121 tcatgtccaa cgggatcgaa acttgccacg gaatctttga aaatatggag tttgtatcct
      181 agattatacg catcgactgc tgtatgcaac acacagatat ctgtacatac gccggtcaaa
      241 taaatatctg tgatctggcg ttctcgcaaa cggatgtcta gatctgttcc actaaaagcg
      301 gaataatgcc gtttgtctat ccaataaaca ttttcctctt gctcatagtc ttggtataaa
      361 ctttttaaag agccgtacaa ttcccgtcca cccgttccta tcacattatg cggaggaaat
      421 aagcggttct ccggatgaaa ggaatctttt ggatcatgcg catcaatggc aaaaacgaca
      481 aaatcctttt gatcaataaa cttctttgta tgagcagtca gctttttttc aattacttgt
      541 cctgctgtcc cagtagtcag ctttccatcc tctgcaacaa aatcatatgt gtagtcaatc
      601 gagatcaatg cgttcatctt agtcctcctt atacgagatg tttgacaaat tcgatcacca
      661 tttctgctga tcgtttgcct gcgtcttcga taaattcgtc aaagctttgt gtcgccgagt
      721 gatctgctgt gtcgctcatt gcacgtacga tcaaaaatgg gatattgaac tgacgagctg
      781 tttgtccaac agcggctcct tccatttcgc aagctaatgc ttcagggaaa ttcgttaaga
      841 tttctttgat tttatctggc gagtcgacaa atgtatcacc tgtaacgatc aatccttctt
      901 ttgcgttcaa attcgttgct tttgctgctt taaccatttc actgcgcaaa tatgtgcttg
      961 cttcataata tagaggcatt cctggtaatt gtcctgggtt gtagccaaat cctgttgcat
     1021 ctgcatcaaa ataagctact ttgtctgata taacgatgtc acctacttgt aagccttcac
     1081 cgattccgcc agctgaacct gtattgatca ccatgttcac gccgtattgt tggatcaaca
     1141 gacttgtggt aatagatgct aagacttttc ctataccgga acgtacgacg atcacttcgt
     1201 ggttacctaa tgaacctgaa ataaataaag cgcctgcgcg ttcccatgat aatggttcgc
     1261 ttaggttctc tctcaaaatt tttacttctt cttccattgc gccgataata ccgattttca
     1321 tctttttaat tccttctttc tatataaatg cgattgctaa aaaaaccaca cataacatta
     1381 ggataacaat aataagagat ttcatcaaaa aagagttcca tttggtcgtc ttttcccgtt
     1441 cgctgatcct tgttttcgtg attggtttat tctttttgct ttctttacga taaaagctgg
     1501 caatcttttt ttcttcttgc tgataagctg tttctgcttt tcgctgtttt tttaatgact
     1561 cgcttgcttg tgcttgttgt cgcttgcgaa gttcgcttcg cgtaataagc ggtcctttgg
     1621 ccataagccg atccctctac tttcctttgg tcaatagttc ccagtattga atcgcataaa
     1681 tcgtctttgc atcacaaatc aactgatctt tcatcgcttg ttgcgcctct tcaagagtta
     1741 gatgatacaa ctccagtact tcgtcttcat cttgtgctaa aggattctcg accttctcta
     1801 ccccttgtgc atgataaata tgaaggactt catttgcaaa acctggtgaa agatacatcg
     1861 aagtaagatg gctcagcgac ttcgcacgat agccagtttc ttcttctaat tctctagctg
     1921 ctgtcatttc gggattttgt ccttctcctg gatcgatttt tccagctgga atctccaaaa
     1981 tcactttttc taaaggtttt cgaaattgtt tgacaagaag cagacgatct tgttcgtcaa
     2041 aagcaatgat cccgacaccg ccaggatgaa ataccagttc tctcttcgaa gttcctccat
     2101 ctggcaaacg aacttcgtct acagcaacat caataatttt tccgctatag atttctttgc
     2161 gactgattgt tttttcttca aattgctcat tgttcagcat atcttctcct gctttctttg
     2221 taatcataac tgcttttttt tcatttttca atttttctca aaaactcctt attagtttac
     2281 catagataaa ccttagattt tctctaaata tagaaaatcc ttctttagtc cgatactctt
     2341 tctagtagtc cgtatgctaa aataagtatg taatcgaata acgaaaagaa ttcaatactc
     2401 aacgataaat gacatggagg gtttattatg ataaaacgaa attggccgtg gcttctagca
     2461 ttggtcttgc tatttctctt tgtccgaaac aatagttttt cttttgttct aggactttta
     2521 ttgataggtg tagttttagt tttgtgggga ctctttggtt cgcgcaggaa aaagggaaaa
     2581 caagaagaaa ttcctgcact gactgacgaa cttgaaactc actatgaaaa aagcggtatg
     2641 acagcgaatg aaatttcatt ttttcgacaa acaatgaatc aaacaaaaaa tgagatcaat
     2701 caattgcaaa tgaatatgca gcagacagcc aaacttaaag caatcgatct ccgccatgat
     2761 ccagtcaaag cagcgaaagc tttattcaaa gaattggtga aagaaccaaa ccgactgcat
     2821 gaagcaagtc agtttcttta tacgcatctg ccgaatctag ttgatttgac aaataagtat
     2881 aatgagatca atgaccatga gatcaaaaac aaacagacct atgaaaaact agaagaaagc
     2941 gcgcagatca tcgaccagct gtcagcttta atcgcacaag attatcaaaa attcgttgct
     3001 gaggatctag atgatatcga cgtagagata tctgttgcga aacagagctt aaagcgtgat
     3061 aataaatatg aaccagaaca aaaggattaa ctcttttgtt cataaaagaa gactcggaac
     3121 attcagatga tgtctggctg tttcgagtac tttttctaaa gtagagacat tcatgtaaga
     3181 atcgagaaca gattcaacaa ggaggaattt tttatggatc ataaaccgac tgaaacaaaa
     3241 gatgttacac cagttaacga tacacttgaa gatttattga acaacccgtt ttcaactcca
     3301 acagatacgc tgaccacttc acaacaagcg gagattgatc agctccaaga gcaacagaca
     3361 gctgctcgtt taattgacaa actaccggcg gaacgccaag aacaagctaa acagctagca
     3421 gcaaaaatcg atgctaatga tgcacagtct gtcatcagct acggatcggc tgcccaagca
     3481 aaattaagtg aattctcaca atcgatgttg aatcatgtgc aagcacaaga tattggtcct
     3541 gtaggagatt ccttaactga actgatgtat cgtctccaag aagccaatcc tgacgaactg
     3601 cgtgccggag aagggaacat cttccagcgt gtcttcggga aggtcaaaca atcgatctat
     3661 gaagtgacag caaaatatca aaagattggt gcacaaattg acaagatttc agtgaaatta
     3721 gataaagaaa aagacggtct gctaaaagat aatctgatgt tagaacagct ttaccagaaa
     3781 aacaaagact actttgatgc actgaatatt tatatcgctg ctggagaatt gaaaatggaa
     3841 gaacttcaaa caacgatcat tccagaagcg atgaaaagag cagaagaaac tggcgatcag
     3901 atggatgttc agattgccaa tgattacacg caattcctag atcgtctgga taaacgtacg
     3961 catgatcttc gcttagctag acagatcacg atccagcaag caccacaaat ccgtttgatc
     4021 caaaacacaa atcaggcctt ggctgaaaag atccaagcat ctatcgctac agccattccg
     4081 ctgtggaaaa accaagtcgt gatcgcattg accttgcttc gtcaaaaaga tgcagtaact
     4141 gctcaacgcc aagtctctga aacaacaaac gacttattga agaaaaattc agaaatgctg
     4201 aaaatctcag ccatcgaaac agcgaaagaa aatgaacgtg gaatcgtgga tatcgagacc
     4261 cttcaaacca ctcaaaatga tttgatcgaa acaatccaag agacattgcg tatccaaaaa
     4321 gaaggaaaag aaaaacgtcg tcatgcagaa gtagagcttg gacacatgga agaagatctg
     4381 aaacaaaaac tgttggattt aacccaatag atcacctttc gcttgttact aaaacaaacg
     4441 cccaacaaca gtttattaca actgttgatg ggcgtttttc ttatctttct tctaacttct
     4501 ccattggagt ctatttctca ttcatcttgc tgtgtccata gccatagcca aaataaatga
     4561 tcagtccaat aaccattacg ataccgaaca cgatccatgt cacagtttgc agacgaagca
     4621 tcaatacaat acaagtcaaa atggagacga ttggcaatag cggaacgaat ggcactttga
     4681 attctccagc ttttggtttg ccaaacattt ttctcaactt cagtaagcct agactaacaa
     4741 gcatcaaata ggcgagcgcc atgatattcg ttagttccgc taatacattc aatgggaaaa
     4801 atccggcaaa gaatacagct gccacaccag cggcataagt cgcttttttc ggtgtacgat
     4861 gcttttgatc gatttctgtc ataaacttag gaagtaagcc atccttgctg acagcaaaca
     4921 gtaaacgagc aagtgaatac atcatcgaga tcgttaccgt cagtagcgtt aaaattgccc
     4981 ctacagcgat caccgcgccc actgttccat gtcctacata cctcattgca aaagccactg
     5041 ggtcattgac tcctagttca gtatacggaa cgattcctgt caagatcagc gtcacgatga
     5101 tgtaaaggac agtagcaatc agtatcgtac caatgattcc tcttggcaca tctttttgcg
     5161 ggtttttgac ttcctcggct gccattgcaa cggcatcaaa tcccaagaaa gcaaaaaaca
     5221 caagagctgc accatctagc acaccggaaa aaccaaaagg catgaatggc tgccagttat
     5281 caggtttaac gaaaaatatt cctacaatga taaacaacgc gatgatacca aatttgacat
     5341 ataccatggc attattcaaa cgtaatgctt tcttggcttc aagcgacacg atgtaagtga
     5401 cgaatatcac tacgagcacc gcaatcaagt caatgtatgt accattttcc ggattgtacc
     5461 cgccagttaa tgcttgtgga agttcggccc ctaaactttt caaaaaacct tgcatatagc
     5521 cagaccatcc ggaagcaaca gaggaaaccg ctagtaaaaa ttccccgatc aacaaccacc
     5581 ctgtcagcca ggcagcaaat tcaccaaata caacatacag ataggcatat ggcccaccaa
     5641 tcactggcac tcgcgaagca aattctgcga aacttagtcc agacaaaatg acaacgattg
     5701 cagctaagac aaatgaaagt gacagtgctg gaccagcatt ttgattggcc gcaacccctg
     5761 tcaccacaaa tattcccgta ccgatgatcg caccaattcc aagcatgatc aaatcagacg
     5821 tttttagttc ttttttcatc tcactcgtat gattgagatt gatctctttc ttacgaaaca
     5881 aatccattga agttcctccc cattttaggt tggaaaacag cgattaaact gttttcatat
     5941 accctaaaag gataccacct aaaatgacta aaaggcaacc aacaataaca taaatgagct
     6001 cttttttcgt ttttctttcg ccaaggatga aaatcccacc taaagtagag ataatgatcc
     6061 ccatttgtga aagtgagaag ccaacagcta aaccaagtga tttgactgtt agaagcatgc
     6121 agatgtttcc taagccccat aataatccac agatcatgtt tttccacaca aactgatcga
     6181 ctttaacttt acggaaagca aagaagcttg cgcctaagat cattccgata ctttgaggta
     6241 agataattga catcgcatcc aaattcgccc agttgacgat gatggtatat acaccataac
     6301 caatcgtaga gaagatcaat gctctaaaac ccttaccaaa atcaagcatt ttattatctg
     6361 tatctatttt tccttcgtca tcttgtcggg cagtcaaata cgcaccgctt acaagaagag
     6421 ctaaagcaat aataccgtat acataatctt tcgtttgtgt ccattcatgg aagaaaacgg
     6481 ctcccgcaat cgtattcaaa attaattgaa aaccagtaga caatggtagc cctacagaaa
     6541 cacccatgta cttcattcca tggaactgtc cattttgtcc aacactccaa gctaagccgg
     6601 ataaaaatcc gatcaagaaa atccaagggg tgattacagg actaacaacg aaaaagacaa
     6661 ctaaagaaaa cagaaatgca ccgatcgtca ttcctagtgt ttgttgattg gcatcgccac
     6721 caattttacc acttactaaa ccaatactac cccatgccaa catagggact aatgctatta
     6781 aaatttccat aaccaatctc cttttatttc acatgataag aaacttatca gcgaaaacgt
     6841 taacaacaca agcacttttt ttcgtttcta acgattttct aacgtttttc attataaaaa
     6901 tttaagattg ggaaaaataa agtcattgtt gtcccttttc cttcagttga ttcagccgtc
     6961 aaatggatac ctaatttttc ggccagattt tttgctaaat aaagtcctaa tcctgttgaa
     7021 tgtgttttgc taagtcgacc atttctccca gtaaatccct tatcaaagat ccgtttcaag
     7081 tcttccgctg ggataccgat ccctgaatct ttaactgaaa ggctgactcc ttgcgcttcc
     7141 ttttctatgc tcacaatgat gtttccgtga tccggcgtat atttgatggc attactaagc
     7201 aattggttga agataaaagc gatccattta gcatcggtca aaacagtatg atcctcacca
     7261 acgatctcgt agcgaatatt tttttggata aaataatttg cctgactgcg tatcacaggc
     7321 tgaatgattc cttttagtcc atattcttgg atgaggtagt cccgcgagaa actgtcgagt
     7381 cttgcataat acaaaacttg ttctacgtat tcatcgattt ttgataattc attttctagt
     7441 aatgtatact tttgatcgtc aatatcgaac tcgatcgaac gaactagcaa tttagaagcg
     7501 gaaagtggca ctttgatttc atggacccat gagtcaatat aatctttttg gtcttgttga
     7561 ttactgattg ctgattgcat tacttcttgg tgttcacgga tcagctgatt gatatattct
     7621 tctaccagtt tttcttcttc tgtcctccca ccactcaaat aattttgcaa aggggaagtt
     7681 ttttgtatgt cggctaattt tccccaccat cttctcttgc tcaagtaacc acccagcaga
     7741 taaaaaatca gaaagacgcc ctcaatcaaa gctaaataag caattgtgct caaatcaact
     7801 ttgatgtttg gcgccagcca catcacaaag atcgtcaatg caataaaaaa cagccatccc
     7861 aagatcaatg tccactgatc tttcaaatat ttaaaaaaat tcatcttaac cgctcatcct
     7921 ttcagggaac gatatatccc tgtcctactt ttgtttcgat atatccttgg atacctgcct
     7981 gttcgatttt tcggcgtaac cgattgatgt tgactgtcaa tgtattgtca tctacaaatc
     8041 gttcgtcatc ccacagtgct cgcagcaatt tttcccgact taagatcttt ccattgtgct
     8101 tcatcaaaat aaataataga cgatattcat ttttgctcaa atcaatgatc tctccgttga
     8161 tttccatact tccgttgtca acattcaacg taatgccatt gtggctcatc atttcactag
     8221 ataattctgt gtagttgtaa gaacggcgaa gtaatgcatt gatttttgca atcagtacat
     8281 cgatttggaa atgttttgtc acaaaatcat ctgcccccat gttcatagcc atgatcatat
     8341 ccatattcgt attcctgctg gagataaaaa tgatcggtac tttcgatact tcacgtattt
     8401 tttgacacca ataatagcca tccaaaacgg gaagattaat atctagtaat acaagctgtg
     8461 gttcttctct ttcaaagtct gagaacactt gattgaaatc ggtcgttcca aaggtttcaa
     8521 attgccattt ctcaagttcc tccatgatca attgtcgaat gatctcttcg tcttcgacta
     8581 ccatgatttt tgccataaaa aatccctcca tctttcttct tgctactaca atatcaaaga
     8641 agcccttgtg aaacaagttg gcttacctgg aaaatgtcat tttagcaaac gttaaaaaaa
     8701 actggaaata tgcgatttaa tcgcgtttgt ctcttccaag cagcttaaat ttattatgtt
     8761 attcttaata attggtctat tatctgttat ttttctttcg ttgtttttgt cttttaaatt
     8821 ttcgataaca ccaataaccg aaaagcgtta gcactagcaa tatacctaga aggagtataa
     8881 gtaatcgata aagatggtat ttttttgtct gttctatctt tgaagagact tcttctgtaa
     8941 agggaactcg tcttcctgtc actagtaatc ggtgagtgtt cacggtgtaa ggtgtacaag
     9001 tgataagtgt gactagatcc tgcttttctc taattgctaa tgtatttgtt tttgttggaa
     9061 ggacaacaat tttctcaacg acttcataag cgagcatccg accatacact tcaagataga
     9121 atcggtcatc ttgctccatt tcttcaagat ccgtaaagag ttttttctca gcaataccgc
     9181 tatgggcggt aatcacggaa tgtgtactct ctcctccagt tggaaaagag gtgccttgca
     9241 ggactgtcgc tcctctatct aacaaaagat cattcgtttc atcaaataaa ggcaagctaa
     9301 cattgatttt cggaatatag atggctccga tcatatgttg ttcgtaatat tcttttcctg
     9361 gattttggac atttctaacc gcttgctcaa aaggatcttt gacttgtccc attcctggga
     9421 ttactgatgt atgagcaagc gtctgatttt tcttttcatg cactgctaat tgttgctcat
     9481 gtttttcttc tttatcgcgt tcaagctgct tttgataatt ctcgatcctt ctttgatcca
     9541 aataattgct gagagcatct gctaaaaatg gatatgtaaa aactgcagct ccggcaagaa
     9601 acatcactgc cataaataat tgtaataaaa gactgatttg ggtttgaggt ctattaccta
     9661 ttttcttttt cattttcttc accttcttat ttaaaaaaac tgcagcaacc tttataaaac
     9721 cgattgctgc agcttatttt tgttgcttat acttcagact tcattttaga tttacggtac
     9781 cagctgtacg ctccaatcat caaacttatt ccgattagta agaatgccaa gagcccgttc
     9841 ccaccagtag caggaagtga cccgcgtttc atattcggta ctctttctgg ccctggattt
     9901 tctactccta cgatctgaat ttcttcatta tagcttccat aagagatgat aaattcagta
     9961 aaggctgcct cacctgttgg aagtacataa ccttctggcg ccatggtctc tttcatttga
    10021 taggttccat aatctaaccc ttgaacctca aagtatccat ttccatctgc gacaaattct
    10081 gttgcttgtc cgcttgttgc ccactcaatt ctatctgctc ctgattcata aacagctaaa
    10141 ggcgactccc ctttataaaa tattgcgtat tcagaacggt cttcattcca caattcgaat
    10201 cttgcatctt taagcaattc actgcttgat gcatcatatt tttcaaactt tcttccacct
    10261 gttgtgactt tctctggcgg ctctactcct tcttcataat caaattcatc atttcgtccg
    10321 atttcaataa ccgctgtgtt gttatggaaa tcatccgctt ctagttctgt ggaaaccttc
    10381 aaattatacg tgatcgttaa atctcctcca cgtgcatctg ctaatctacc taaagtatct
    10441 actttggcta ctccattttc ttctgtcaaa atcgtcacga caaacccgtt gcttactact
    10501 tctactatat aatcttgtcc ttttgttaaa atcgtctcgc cggctcgcac ttctatttcc
    10561 tgatcataat aagttagacc aactgtaggc gtatctgtga ttttgtaatt tttgataaca
    10621 gcgcttccgt tttcaaggac agaatcgatg aaataaggaa taggtgctgt gatcgtgtaa
    10681 gaagccgttt ttcctctttc tagatcaata taagaaatcg tttcttgttc tccagcttca
    10741 ttaataatcg ttacttgtct aaggtcgctt tcctctacat tcatctgttt atctgcttct
    10801 ctgatttcgt ttttcggata caaatgcaca tctgtattgt atgtgtcttt ccatgtagaa
    10861 ccatcccaca cgccatccac catatcaggc atcatcactg gcatcataac aaccattgga
    10921 gacgcgattc tggaaatatg agctggcgaa taagtttcta agaaaagata gactttatct
    10981 ctagaagaag gtgcttcttc cgtcacttgg acggtagaga ataccgcttc tccagcttca
    11041 ttcgttgttt gtttgtcaat acttgtcagt cgatatttta aaaaccaact ttctgtgtgc
    11101 cgtttttgaa tccattcaat cgcttcggca gaattaagac cgtcttctcg ttccggtgtt
    11161 aaaggattat ctcgaatcaa atcgtaatat acttccgtta cgtcaaacaa atcaaaatcg
    11221 actcctggaa tattttcttc accaaaatcc gtagaaacca atccgctatt cggtcgttct
    11281 tccggaacag atgagaaacc ttttttgtgt aatgtaatcg tcacttcact tggtttttgt
    11341 gcgacttctt cggctttgac tagttttccg ttcccgaaaa tccctattcc cgcagtaacg
    11401 agtaacagta cactcattcc cgtgacaatc atttttttat tcattttttt ctccccgttc
    11461 tttttttatt aataaaacag cacctaacaa taaaagaatt cctagtaaag aaatcaacgt
    11521 tcttgcttca ttcgtttgcg ggaatacgga ccattttcct gattgacctg gattgcttgg
    11581 accactcggc tctttcggtt tgtccgttgt ttcttttacg gtctcgttat aaacacgtgg
    11641 tgttgcggat tcataggcag agactggaac tttcccggat tctaattcag ccatctcctg
    11701 tccgttaact actacatatt gtggttggcc ttttgcatcc acccaaaatt cagggatgat
    11761 gacctcgatt ctcttacttg cttcatccat ctcgtaacct tccacacctt ttaattcttc
    11821 aaaataatag gtgccagaag gcaagaaacg ttgtcctgtc gtaacaaggc cctctttatc
    11881 cgaaatgaat ttgcttacat ttttgtcatt caaaggatca ttgtctgctg gtttgatcca
    11941 ttgatttttc aagtcattag caggagccat atctaaataa tatttccccc cttctatcat
    12001 ctgatataga gcaaaaacag caccttctaa tggttttcct ttttcagttg ttcctctttg
    12061 acgtccatac ttgaagaagt atggatctct tagataaccg acatttttag gatagatatg
    12121 aatctcttgc agttcctcgg ttgattctgt cgggtgataa attggcaaaa tagcagcaat
    12181 tgggatagct gtctgatcga tatcaacatc caatccaact tctggatcaa tcgattcttc
    12241 gaaaatcaaa taaactgcat cccgatcttg gtttttctta ggtgctttga tacgtgcaat
    12301 cccgtctcct aatccgccaa ccgtatcttt cccagttgtt accgaagtcc ctatttggac
    12361 aagcctttct tctgtgatta gctgacggat attgtttctg ttcgtttcag cgatttgctg
    12421 gacgaattct ttaggagtca tgttttcagc agcttttttt tcatgataat aatcggtcat
    12481 gtcgtaaatg gcaaatgtcg ctccatttag tggcaccgtc tgtgaaatga tatctgctgt
    12541 ttcccctgct tcctcagaga tagccaagcc atcattttca tggtattcaa attgatcgtt
    12601 ataatcgata tctcgaatca tccgtttatg caacacgaat tccacgacat cttcccctga
    12661 ttcttctgcc gacatcgcat gtggaagaag gactgctgca agcggtagta aaacaagtaa
    12721 ttgaagcatc aaacacaaca gctttttcat taccttgctc cctccttttt agattgtctg
    12781 acaaacaaac cataggctgc tcctgcaagc gccatgaaga atgcagcaag caggatatag
    12841 aataatcgtc cggatcctcc tgtagcaggc aacggatttt caggatcgtt cccgacacta
    12901 agctgtaatc tgattcgatt tgtctccaaa agttcatatt ctaactcttg ctgtagatca
    12961 ggcgtctctg cttcttcgtt tggataatac gaaatctcaa cttttagtgt acccgcttct
    13021 tttcctggaa ctacccgatc attttctatg tcaggttctt ctcgataact aatttctaaa
    13081 ataaagtaac ctggaagttt tctatagctg tcaggtgact tcacttcctt gatccgatag
    13141 accccttcca acaagtctga agcattgaat agggaagaat cgtttggatc tggtgccaag
    13201 cctccctcga tgatttcata ctctcctgca ctattttgtt tctcaattga aaattctgcg
    13261 ccttcaagac gtcggctatt catactgtca attttcaaaa gttccaaatc gattggcgct
    13321 agttcatctt ctaaggttac ttgtagtaca ccatcgatga tttcatagcc ttccggcaag
    13381 ggagcagttt cgtcttcgat gaccgtatct tcaatgataa acttaccttc ttcattcagt
    13441 gcaaactgga acacttgatc agatagccga tacccatttg gtgcgacaga ttccgagacc
    13501 tcatattcac caatagacag atgcagaggt tggtcgtaat ttaaatcgac atacttttct
    13561 actcctacgg cacgagaata gaagtatccg atcccaggca aacgtttcga ttcttctggt
    13621 tctaacggat taccagtgta tgctcgatac agcgggaagg aagaatcccc cactttcctg
    13681 atatcgaaac ctgcaccatc taatgtatgg ccttcatggt ctaattttct aactcggatc
    13741 tcccgataat caaacgtatt gtaagcagtg aatgctaccc ataaacgatc ctcttcatct
    13801 gttgtatacg tgagatattg ccaattttct tcacctgttt gcttgagttg gatagtccct
    13861 atagcattat cgtaaagtcg caagatccat gtgtcatttt catcaggttc tttgaaacct
    13921 tctgggttct ggctctcaat gattttgtat tctgcatagt tggtagtttc ttcactatcc
    13981 ttataaacaa atgaatctgg ctctccgatt ggatgaataa ctttctcacc atccacgatt
    14041 acatatttcc cgtcttcatc tactgaatag aacgtgagtc tccctttctc ttcctctact
    14101 tcgttcacac cagaaagccc tttcgctact ggatatccga tttccagtcc gttaccatct
    14161 gtttcataaa gttcaaactc tgcgccattg attggcatat tactgccttc aattagttta
    14221 ttgatattca tgtggattgg cttgaattca tttcgcattt ccagtttgac atacaactca
    14281 tcatactctg tgccttctat gttaggctct tgtacaacag aaagcttgtg atattctcct
    14341 tcataatagg aattcggatc tttaccttcc ggtccgccga ctctcgaacc agatgtatat
    14401 tcatctacaa gctcgtagtg acctaacatc tcatcttcgt tggctgcata ttttttgatt
    14461 tggaattgat acgtctcatc tactaactga taacgtggtg gtccagcgat ctctctgatc
    14521 caaaatatgt cgctgactgc tccagtttca tctcctaaaa tcggcatctt cgtttcaaag
    14581 atcgctattc cgtccgtggt agttttactt gtttcgattg gttcggcttc cccactctct
    14641 ggattttggt catataatgc aaattcgact ccagccaacg gctcgccatt ttgacccttc
    14701 ttgctgactt ggaaattacg gcctttatgt tcgtaacgaa tggaagaaga tgggaaatac
    14761 atccgtccag tagtgatatc attctcataa tcctccaggt tctgaatata ggccatattg
    14821 ttcactgtgc aaaaatttcc gtcttgagct cccgcatcaa gttttacttg gtacttgatc
    14881 ctgaccattt ccccttcacc taaagaaatc ggagaaaatt tataagcttg gttttcccgt
    14941 ccgacatacg ttgtcggagt cgccactact tctggtgggg cttgtccatg acgttcttca
    15001 tcccatattt ctggctcttg gtacttcatg ccgttttctc ctggatctag atggtaaaac
    15061 tgaatatctg ccgatctgcc agctccaaat ggtgagacat taaaaccagt ttcatcataa
    15121 agtgtggctt gctggatcgt tctcttgaag gtagaagaga tatcctccaa ggctgtaaca
    15181 atgtcattct tgttgttcgc attgtaatat cgcggtgtta cgccatcttc ttctaaatca
    15241 gcaatatttt tcaatacatt tcgtccaata gcatctagtc gttgtctccc gctaacgttt
    15301 ccatcgattc ctaaaccaat ggagaagata cttggcgggt tctcttgata cttgtttttc
    15361 agccaatgat gataagcaac tgtgttgatc gcagatgact tttcttgcga agtaggactg
    15421 ccattcgtat tgttattaga agaaccatca ccaacccagt gagtcgcttt attatctcct
    15481 tcttttacct ctccataacg atagtgtaca tttacttcat cttctggacg gttaaagtca
    15541 gatgcatagg taactggatg agtaaaccct gcattagaag tattcccaga aaactcctca
    15601 aaatttctga acaaaacgtc attatcttca gcaatcttat cttccatcac agtccagttg
    15661 ctccaagctc cattagtgct cgtacgataa cttgactgaa tcggtgcata actgaaggtc
    15721 ggtgtcccat ctcccacaac gattaggatt ttttctggat ttctattttc tccgccattg
    15781 tctttataca atgtttcata gccattttta agccctagtg taagcggagt tcctccgatt
    15841 ggtgtacgat ttaatgctgt attctcactt cccgtcaaac gattgatatc atttgtcaat
    15901 ggaaagatgt ccgaactgat ttgctcatgg ttattgatag ctgtactatt atggtaaaaa
    15961 ttcaccatac cgattcgaat atccagactc gggtcagaga gcagatcttt actcatttcg
    16021 tttactgcct caatcaacgc agcattttta gtttgactat tggtcccagc ggttaattca
    16081 ctcatactcg ctgacttatc tagaacaaaa acgatatcga ttggactgat ttcctttttc
    16141 tcgcccccga tgacatctag atagacattg taaagggttg ttgcatcttc aggatgtaga
    16201 tcagatgctg tgctgcttgg cagaacaggt tctacccatt ttttgatgta cgccccgtta
    16261 taatccaagt aactgttttc aaaattccgt tcatttcccc aaagctgaac ggtttgagct
    16321 ggaacgtttc tatcttcttc gcctgcagtt gatccattat tagtagcata gtcgtaattt
    16381 cgccagttcg ctcccccgtt tgtataatca ctatcatcga tcaagttctc tccgtcatat
    16441 ggcgagcctt tgtctccttg atagcgttca ttgctttgtg tccaatttcc taacactttt
    16501 gtatagtcat tcgttgtaaa cttcgggtag cgatgctgtt cgttttcaac ttctccgcta
    16561 ggatagatat attcataggg gtcttgcgta gctgttggcc caagacgctc caaaataccg
    16621 ttgaataact ggcgttgaat gcgctggagt gcttgaccgc tgggtacgat tggttcgtcc
    16681 agcttttcca tctcattttc ttcgctacgt tgaatttcag cggaatcttc tgtatcagtt
    16741 tcattttctt gtaattcttg gttatctatt ctttcatcaa ccaccacttg aagaggtagt
    16801 tacccttcgt tcacatcggg gatcttttct gtttcaaaaa tcaatgtgcc ggtttctgct
    16861 tcttttgaat aaacttttcc gacataccat tcttgaccat cgatcgtctc gacttttagg
    16921 tcttctccat cttcatcata ggaggataga cctgttccac gaacgttttt tacggtacca
    16981 atcccggcgg ctgccgcatc gattgctaaa cgtattctac cttcattggc actttccttt
    17041 ttttcaaaag ccagatgcca ttcaagggtt tcttcttttt caatatactt cccttcaatt
    17101 tttgcatagt cctcatctaa gaatacctca tcctcctttg tttctgttga ctcagcagct
    17161 acatccaggg tcgtcatatg atagactgac tggaaatatg gtccaaatag caaactgaca
    17221 gttactaact gcaaaagctt caattttaac cctttcacat ccttatactc ctttcaaaaa
    17281 tatttgtctt ctttcacaac aatcaacaaa acaatgccca tctaattata atttaattta
    17341 attttaattt taaatcaaat gatatccttt ttagt
//
LOCUS       DADQDV010000061        17006 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.063, whole genome shotgun sequence.
ACCESSION   DADQDV010000061 DADQDV010000000
VERSION     DADQDV010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17006)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17006)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17006
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.063"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..125)
                     /locus_tag="J8S10_002194"
     CDS             complement(<1..125)
                     /locus_tag="J8S10_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HAZ9630774.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVFS"
     gene            complement(229..540)
                     /locus_tag="J8S10_002195"
     CDS             complement(229..540)
                     /locus_tag="J8S10_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HAZ9630775.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPSPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            complement(542..739)
                     /locus_tag="J8S10_002196"
     CDS             complement(542..739)
                     /locus_tag="J8S10_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterocin"
                     /protein_id="HAZ9630776.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(1133..2860)
                     /locus_tag="J8S10_002197"
     CDS             complement(1133..2860)
                     /locus_tag="J8S10_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAZ9630777.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2853..4046)
                     /locus_tag="J8S10_002198"
     CDS             complement(2853..4046)
                     /locus_tag="J8S10_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HAZ9630778.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(4233..4877)
                     /locus_tag="J8S10_002199"
     CDS             complement(4233..4877)
                     /locus_tag="J8S10_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAZ9630779.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4971..5105)
                     /locus_tag="J8S10_002200"
     CDS             complement(4971..5105)
                     /locus_tag="J8S10_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HAZ9630780.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(5107..7239)
                     /gene="feoB"
                     /locus_tag="J8S10_002201"
     CDS             complement(5107..7239)
                     /gene="feoB"
                     /locus_tag="J8S10_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HAZ9630781.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(7236..7709)
                     /locus_tag="J8S10_002202"
     CDS             complement(7236..7709)
                     /locus_tag="J8S10_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HAZ9630782.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            8110..8334
                     /gene="nrdH"
                     /locus_tag="J8S10_002203"
     CDS             8110..8334
                     /gene="nrdH"
                     /locus_tag="J8S10_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HAZ9630783.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            8493..10652
                     /gene="nrdE"
                     /locus_tag="J8S10_002204"
     CDS             8493..10652
                     /gene="nrdE"
                     /locus_tag="J8S10_002204"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HAZ9630784.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10702..11667
                     /gene="nrdF"
                     /locus_tag="J8S10_002205"
     CDS             10702..11667
                     /gene="nrdF"
                     /locus_tag="J8S10_002205"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HAZ9630785.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11756..12895)
                     /locus_tag="J8S10_002206"
     CDS             complement(11756..12895)
                     /locus_tag="J8S10_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAZ9630786.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(13204..13917)
                     /locus_tag="J8S10_002207"
     CDS             complement(13204..13917)
                     /locus_tag="J8S10_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HAZ9630787.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(14171..14872)
                     /gene="nagB"
                     /locus_tag="J8S10_002208"
     CDS             complement(14171..14872)
                     /gene="nagB"
                     /locus_tag="J8S10_002208"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HAZ9630788.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            15106..16638
                     /locus_tag="J8S10_002209"
     CDS             15106..16638
                     /locus_tag="J8S10_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAZ9630789.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(16829..>17006)
                     /locus_tag="J8S10_002210"
     CDS             complement(16829..>17006)
                     /locus_tag="J8S10_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAZ9630790.1"
                     /translation="VFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQ
                     TVVFKGKRNLENKK"
BASE COUNT         5278 a         3495 c         2910 g         5323 t
ORIGIN      
        1 gaaaaaacac attccactaa atttgatgcc ggttttcctt gaggttttgt tccagcacct
       61 cctttaattt ttttaagctc ttgatctgaa cattgtttag catttagtct atttttttct
      121 tccattacga ttccccctac aaactataaa tacttttatg tcactgattc aatataccta
      181 tttttctaat caaaaaattt tgagacatat ttaatattat aagtatcatt aaaattgaga
      241 tttatctcca taatctgctc gatataaacc atttattcca gcagttcttc caatttcact
      301 caaatttctt attaattcct cttgatattc agtgaatctt attttattag tataagcagt
      361 aaaatataga taattcacca atctatttat taaaggactg ggatctaatt catatttttg
      421 tttttctaat tttaaatata ccttttgtaa aacctcaaga atatcagaat atttaggatc
      481 tttacttata gatatatcat tatataattc atgaacaatt tgcttagcat tttttttcat
      541 tttagcactt ccctggaatt gctccaccta aaaaaccacc tatagacatt cctgcaatac
      601 aagtagttgc cttggcccaa tcgaccgtac atttattttt agtgcaatac actccatttc
      661 cataatattt tccactatga gtggtacccc catagataag ttgtgtctct ttaatagaca
      721 aaatttttaa atgtttcata atctaatcac ccctaaatta atgtttttag actattattc
      781 taacattcat taaatttcaa aaaacaattc cttcttgaaa cgtagcaaaa taattcctga
      841 ataagaattt aatcactttt aagtatataa actatgtata ttctttaata ttttttgaga
      901 atgcacttcg tacataataa actttaatca cattagtctt tcatacctac gatcgatctc
      961 tttgactcgc acccataaat tcataatagt ttgtcggcgt ctttgaacgt ttcgaagatg
     1021 agctacgcat tctctttttt tatagacaaa aaagatagag acgaacatgg agcttccaaa
     1081 tttggatatt tgatccaatt ttggaagctc catttatttc gtgtctgtct ttttattttt
     1141 tccagctttc gactaattct tggttctctt tgatccagtc ttttgctgct tgctgtggat
     1201 cttttccatt gttgatttcc aacataactt tttccatatc tttttctgac caatggaaat
     1261 tgtctaatac tttgtaagct tctggctggt cttctttcaa tccttttcga accatcgtat
     1321 ggatctgctc ttcgcttccc attccgtttt caggatcttc taagtatttc agatcatatt
     1381 tggcaaacat ccaatgaggt gtccatcctg taactacaat tggttcgtgt tttttgatcg
     1441 cttgacctag tgcaacggtc attgctcctg aagaagatgt ctctactttc cagtctttca
     1501 agttgtcata tttttggatc gtgttttcag cagccgtaac tacaccagct cctggctcga
     1561 ttcctatgat tttcttacct gcctgatcgg ttaactcatc gatcgaattt acatccatgt
     1621 aggctggcac tgctaaacca acttttgctc ctgtcaaatt ggcacctagg tcttcgactt
     1681 gatctttata ttgtgcatat tgtgaaccat gagttttagg tagccaagct gaaaccatgg
     1741 catctgactc gccatttgaa acagatttcc acatgattga attatctaat ggcgtcatcg
     1801 ttacatcata gcccatttgt ttcaatactt caccgactac atttgttgaa gcaacttctg
     1861 tatcccattc aacataagat aagttgatac gttttgtttc tttggcagat gaaaaactcc
     1921 ctataccaat cgcacctaag atcactacta ctacagcacc aatgatcagt ccttgacgtt
     1981 ttttactttt ctgtgttgtt gctcctgcag cttttttatt gtttggctgg ttcaaatgct
     2041 gtgtaaaacg gtcaatgatg attgctaaga taactaatgc aaccccgttg acaaatccat
     2101 tcccgacttg tgctctttgc aatgctgata atacgccgcg tcctaagccg ggtgcaccga
     2161 tcatagaggc aataacgacc attgaaagtg acagcattgt tgtttgattg atccctgcca
     2221 tgatcgtact tttagctaaa ggcaattcta gtttgaatag tttttgacga cttgtgctcc
     2281 cgaatgaatc agaagcttct actaattctt taggaacttg tcgaatccct aaattcgtaa
     2341 aacgaacggt tggtggcaga gcaaagatga ctgaggcaaa tacccctgga accatcccga
     2401 taccgaaaaa tgcaactgct ggaatcaaat aaacgaatcc tggcattgtc tgcataaagt
     2461 caaggatcgg tttgataata ctttgggctt tactgctttt tgccatcaag atccctaatg
     2521 gtaccccaat gatgatcgag atcacactag ataaaagaac aagtgtgaca gtattcatca
     2581 aatcattcca tagaccttgg ttataaataa accatagacc gattaatgtg aacaacgtaa
     2641 gtcctggacg tttcttagaa ataaagaaag ctgctaccgt caataacaag ataaacaaag
     2701 gagctggaat cactaacagt aaatttgtaa tccccgacat cactgcctgt ccaatcgttt
     2761 gtaaaaatga aaataggcca gaaaaagttg tcgtaaacca ttctgtgata ttttctaccc
     2821 agtttgccac tggtaattga tagttcaata gattattcat gttcactcac ctcgcttgtt
     2881 tctgctaatg cttcaatcac actacctcgg atgacgacac cttttaattt tccatcctct
     2941 acaactgcaa gtggagtcgg tgagtcataa ataatattga aaatatcact taccaccatg
     3001 tctttcccaa tcaccgtcac attttcatct aggaagtcga tcaatggacg tttttgcttc
     3061 ctagcttcta acgcttgatc tgcagtgatg atccctttca ggtgtctctt tctgtcaaca
     3121 gccatcagca tgctgacttc ttcattacgc atccttgtca atgcaacgtt tggtccatca
     3181 gattcgatat tcgtcgtcaa tgcaggtacc atgatgtttt gagccgtaag cactttggaa
     3241 cgatcgactt cttccacaaa ttcacgtaca taatcatttg ctggattggt caatatttct
     3301 tcacctgttc cgatctgcat gatttcgccg tctttcatca aggcgattct gtccccaatc
     3361 cgtaaagctt cattcaaatc atgggtaatg aaaataatcg ttttttgaac attggcttgc
     3421 aggtccagta attcgtcttg catttctcgc cggatcagcg gatcaagagc cgagaacgct
     3481 tcgtccatca gcaagatctc aggatcattt gctaaagctc tggctaggcc aacccgttgt
     3541 tgcatcccac cagataactg actaggatat tggtctttaa atgaaagcaa actagaattt
     3601 tctaatgctt tttctgcttt ttcttgtcgt tcttctttag gtacaccacg gacttctaac
     3661 ccgtattctg tattttccaa gatcgttcga tgtggaaaca gaccgaagtt ttggaaaacc
     3721 atattgattt tatgacgacg gacttctcgc aattcttctt tgcttaactt cgatacatct
     3781 tctccatcaa tatagatact gcccgaagtt ggctcaatca gacgattcaa tagacggatc
     3841 aatgtggatt tcccactccc ggaaagcccc atgatcacga agatttctcc ttcttttacg
     3901 tcaaaattca cgtcatacac accaaccgtt gcaccggttt tctttaaaat ctccgttttc
     3961 ggctggtgat cattcatcat atctaaagcg gcttgtgtct ttttaccaaa tatctttgtt
     4021 aaatgtttta cttctacttt taccaaacaa attctccttt tttatgtaaa ttcatttttc
     4081 tttctgaaaa aagtgaccac actatgttaa catcatgtag tcactttgtc aaaaatgaaa
     4141 gaaatttgct tgtccaaact gaaaaaaact tggctaaatc tttgtaaata aaaggtttag
     4201 ccaagttaat atttttttaa tatttcacac aatcattctg caagctgatg ctccgggtaa
     4261 aaaaagtttg tcatacgctg tagtgtatat tcatttccaa taaaatgaac gatgtcccct
     4321 gccgtaaatt tagcataggg gccaggtgaa acaagcagtt cttcattatg agaaattgcg
     4381 ataactgtgg cgccagtcgc ctgccagata ttcaactcgc taattgaacg gtccagatgc
     4441 attgcttttt ctgataaaga taattcaaac ggaagtaaag gattcatctt atgtattcgc
     4501 ttcgtttgat tgaccagctg atccaataat tgagaaaaat gattcagctc atcttgttgc
     4561 ttctccacac ttgccatgat ttctgctttt gtatcttgga tggattgtac atcttgatat
     4621 tgcaatagga aatcttttgc tttttccttc gaagcaacaa atgccccact tccatgccgt
     4681 acttccatga ttccaagatc taccagcaca ttgatagcct tgcgggtagt ctcaggagaa
     4741 gcattgtacg tactggcaag tgttgagcgg gcatggatct tctcacccac tttatatcgg
     4801 ttttcaacga tacgttcggc taaatcaaca gcaatctgct ggtagcgcgg gcggacgatt
     4861 tttttctttc cagacatttt ctttcctctt tcttttttta ctttccctca tcttactatg
     4921 ctctagcaaa ataagcaaaa aaggggagaa tagcctcttg caacgactga tcatcgcttg
     4981 atctgttcct tttttactgg gcaagctgtt tgacagtcat cacaattctt accggatttt
     5041 aaacgagtat agacaattgc gcctgcactt ccaaagatta acacacttaa taagaatgtc
     5101 gccatcctat tcctctcctt ctaatgacaa tatagtataa aactggttct tggattttgg
     5161 ctgacggaac aaaacataaa cgagtcctat catcagtaaa atagcaagat acgtccctaa
     5221 cgctacctgt ccaccctcca ataagtgtcc caactgataa atcacaaaac taactaaata
     5281 agctaaaccg cattgatagc ctatggcgat ccaagtccat ttcttggcat tcatttcccg
     5341 atggatagcc ccaattgccg caaaacaagg cgcacaaagt aaattgaagg ctaacaatga
     5401 ataagctgct gcgggagtat atgtgtgttg tagcacttgc cagatttctc tgccattttc
     5461 ggatacttcc gcatgaccaa acaaaatacc aaatgtgcca ataatatttt ctttagcgac
     5521 caatcctgta atcgctgcga ctgttccttg ccagtttccc caaccaagcg gctgaaaaac
     5581 aactgccagg attcgcccga aaaaggctaa gatactttgg tcttcagaaa caggttgagc
     5641 ataaaaatta taagaagagc tgaaccagat cacgatacta gaaacaaaga taatcgttcc
     5701 tgctttttta acaaaagact tgctgcggtc ataggtttgt cttaggaccg ctgaccattg
     5761 aggaaaatga tatgcgggca attccatgat aaaaggagct gtatctccag caaacaaacg
     5821 tgtttttttc aagctgattc cagagaaaat aattgcagtc ataccaagaa aataggcaga
     5881 aggagctacc caagattgat gaggaaaaaa ggcccctgct actaaggcaa taatcggcaa
     5941 ctttgcagaa caaggcatga aggttgtgac catgatcgtc aaacgacgat cttgctcgtt
     6001 ttcaatcgtg cgactggcca tgacgcctgg cactccacat cctgtagcaa tcagcatagg
     6061 aatgaaggat tttcctgaaa gaccgaattt cctgaaaagt cgatccatga caaaagcgat
     6121 cctcgccata tatccgcagt cttccagaaa gctcaagcat aaaaacaata taatcaattg
     6181 cggtagaaat cctaacactg ctcccacgcc tgcgatgatg ccgttcaaga tcagctcctg
     6241 catccatccc gctacttgcc attcagctaa caatctgcca acatgttctg gtaaccatgt
     6301 accaaacaat gtgtcattga tccaatctgt ccccattgtt cctactgttt gaatagccag
     6361 ataatagatc agccacatca caaatgcgaa gatcggcaag gctaaccaac gattcgttgc
     6421 aatctgatcg attttgtcac tcatcgataa ttggaaagaa tcatttgaca caacacagag
     6481 tgtacatagt tgggtaataa attcataacg ttcattgacc agaatcgtct cactatcgtc
     6541 gtccaatagt ttctctgtta actggatcag ttgctcgatc tctttttgct gagaaactgc
     6601 tatctcgtaa tcctctctta ccttctgatc tcgttcaaaa tatttcattg cataccagcg
     6661 tttcttgccg ctttgttctc ctagtacatc ttcaatttca tgtaaagctg cttctaaacg
     6721 tggatcatat gtacagggaa caggaataga aggccgcttt tttgcagact cctgaatctt
     6781 ttcgattagt ttttcgattc cttgcttttt caatacgctg attggtaaaa ctggtacacc
     6841 aagaccatag gaaagctttt ctagattgat tttttttcct tcttttttga tgacatccat
     6901 catattcaga ccaatgatca taggaatgtc taaatccaat aactgcgtag ttaaataaag
     6961 atttcgttct aaattggtag catcaataat gttgatgatc agttcaggct gttcctgaac
     7021 caaataatct cttgcaatca cttcttctgg tgtataagga gacaaagaat agatgccggg
     7081 taggtcctga atatgaatgt tcggattttt tttcaacgat ccttcttttt tttctactgt
     7141 tacgcccggc caattcccta catattgatt cgaaccagtc aagagattga acaagctagt
     7201 tttcccgctg tttggatttc cgactaacgc gatattcatt ctttttcctc cctttgtatc
     7261 aagattagtt cggcctctga ctttcgtaac gtcagttcat accctcgcac tgtcagttcg
     7321 attggatctc ccagaggggc tagttttcgg ataactattt ttacatttcg cgtcaatccc
     7381 atatccatta accgtcgctt cactgcgcct tgtccgtgga ttgctacgac gatcccagtc
     7441 tctcctgctt ttaattgatc aagagaagtc cagctttcag aggaagcagt ctttttattg
     7501 acaaagattt gacctagtat ttcccgactt actgccactc gatgactttt taccagtaaa
     7561 atggcattgt tgcctgataa attgacgacg acgattttac ttccggcaac gatcccgata
     7621 ttttgcaaat ggcgttttgt tttttcttct gtttcgattc gttcgacttg ataaacgaaa
     7681 ttctgctttg cctgcgctaa ggtctgcata ttgattcctc tcttgtgaaa taaatcatgt
     7741 attaaaatca ttcattatat gttctaattt tcttacgtgt tacgcaaata aatgagaatc
     7801 attctcacat agaatactct cggtaattga gaatgtcaat tatacttgtg atattatgag
     7861 cgaatcttta gtattgatag ataaaaatga gaaaaaaata tttcttcata gttttccaca
     7921 attttttctc tattaaattt gctattttcc cacacgatac ttgttttcag ctcttttttc
     7981 aaaaacacaa aacttagtat tccacagttt ccacaacaca atatgtagtg tttgttgttt
     8041 gactttttta ctaagagttt tatactatct attatagata ataagaatgt gttagaggag
     8101 gcactcacca tgaacgtaaa aatcttttct aaaaataatt gtatgcaatg taagatggtc
     8161 aaacggtttt taacagaaaa tcaaattgct tttgaagaag tcaatatcga tgaacagcct
     8221 gaagcagtag actggttgaa agcacaagga ttccaaagtg ttcctgtcat tacttctgat
     8281 gcagaaacag ttatcggatt ccgtcctgat cagttgcgta aacttgccag ctaacatgac
     8341 taaaagaatc aaaacgtgat acatggattt gaagggcttg agacagcacc agtttttgtc
     8401 gcaaacttcc aaatcctttt ttaaagctta aaaacaatgc aatgatttgc aatcaagcat
     8461 catcaaatac gaaatgaagg ttgggcgtac gtatgagtct taaaaattta caagatgtca
     8521 gttatttcaa gctgaataat gaaatcaatc ggccagtcaa tggtcaaatc cctttgaata
     8581 aggataaaga agctttagtt gccttttttg aggaaaatgt caaaccaaat acgatgactt
     8641 ttccatctat tatggaaaaa atcaattact tgatcgatca agaatatata gaagcagaat
     8701 tcattcaatt gtattcacca tcatttattg aaaagctata tcaatttttg gacgagcaac
     8761 atttttcttt caaatctttt atggctgctt acaaatttta ttctcaatat gcgttgaaaa
     8821 ccaacgacgg ttccgcttat ctggaaactt atgaagatcg agtagccttc aatgcgcttt
     8881 actttgcgaa cggggatgaa gaattagcac ttgctcttgc agacgaaatg atccatcaac
     8941 gatatcagcc agctacacct tctttcttga atgctggacg taaacgtcgg ggcgaattgg
     9001 tgtcttgttt cttgactcaa gtcactgacg atatgaactc tatcgggcgc tcaatcaact
     9061 ctgctttgca attgtcccgt attggtggcg gcgtagggat tactttatca aatcttcgtg
     9121 aagccggcgc tcctatcaaa ggatatgagg gtgctgcaag tggtgtcgtt ccagtcatga
     9181 aattattcga agatagtttc agctattcta atcaattagg tcagcgtcaa ggagctggcg
     9241 tggtttattt gaacgttttc catccagaca ttattgcttt cctttcagca aaaaaagaaa
     9301 atgcagatga aaagattcgc gtaaaaactc tttctcttgg cgtgatcgta cctgataaat
     9361 tttatgaatt gacacgtaaa aacgaagata tgtatttatt tagtccatat agtgtcgaaa
     9421 aagaatatgg tgtcccattc tcttatgtaa atattacagc tgagtatgat catctagttg
     9481 caaatccaaa cattcgcaaa caaaaaatca aagcgcgtga tcttgaaaat gaaatctcaa
     9541 aattacaaca agaatctggc tatccttacg taatcaatat tgatacagcg aaccgcgaga
     9601 atccaatcga tggcaagatc atcatgagta atttatgttc agagatttta caagttcaaa
     9661 cgccttctgt gattaacggc aaacaggaat atgaagtatt aggaacagat atctcatgta
     9721 acttaggctc gacaaatatc gtgaatttga tgcaaagccc taactttggt caatctgtgc
     9781 gtacgatgac tcgtgcattg acatttatta cagatgcatc tgatatcgat gtcgtaccac
     9841 cgatccaaaa cggaaataag ctgaatcata cgattggatt aggtgccatg ggcttacaca
     9901 cttatcttgc aaaagaacaa atggaatatg gctcagagga ttcattagac tttacaaata
     9961 tttacttcat gctgttgaat tattggacac ttgttgaaag caacaatatc gctcgtgaaa
    10021 gaaaacaagt tttccataat tttgaaaaat cagcttatgc tgacggcact tatttcgaaa
    10081 aatacgtaac tggagaattc cagccaaaat cagaaaaagt caaagcattg tttgaaggca
    10141 tttttatccc aactgctgaa gattggaatg ctttgaaaca agcagtaatg aaagatggac
    10201 tgtatcatca aaatcgcttg gcagtagcac caaatggctc aatttcatat atcaacgata
    10261 cgagtgcaag tattcatcct atcactcgca tgatcgaaga acgccaagag aagaaaatcg
    10321 gtaaaattta ttacccagcg ccttatctat ccaatgagac gattccgtat tacacttctg
    10381 cttatgatat ggacatgcgt aaagtaatcg atgtttatgc aacggcacaa caacacgtcg
    10441 atcaaggcat gagtttgact ttattcatgc gttctgaaat cccagaaggc atttatgaat
    10501 ggaagacaac aacgaagcaa acgacacgtg atttgaatat tttaagacat tacgctttcc
    10561 acaaaggaat caaatccatt tattacgtac gtacctttac tgatgatgca gaagaaatcg
    10621 gaagcaatca atgtgaaagc tgcgtgatct aatatcatag atagattcgc ttattcatat
    10681 tttaattaaa ggagcattct catgtcagaa acatattatg aagcaataaa ctggaatgaa
    10741 attgaagata tcattgataa atccacttgg gagaagctga cagagcaatt ttggctagat
    10801 acacgtatcc cactttcaaa tgacctagat gattggcgta cattgtctca attggaaaaa
    10861 gatacagtag gacatgtatt tggcggtttg acactgctag atactgtcca atctgaaagt
    10921 ggcatggatc agttgcgtaa agatgtccgc actccccatg aagaagccgt tttgaacaat
    10981 attcaattca tggaatccgt tcatgccaaa agttattctt ctatttttag tacactgaat
    11041 acgaaaaaag aaatcgaaga aatttttgac tggacaaata cgaatcctta tctgcaaaaa
    11101 aaagctgagc gtatcaatga aatctacaaa cacggtacac cgctagaaaa gaaaattgcc
    11161 agcgtctttt tagaaacatt cttgttctat tcaggttttt atactcctct ttattattta
    11221 ggaaacaaca aattggctaa cgtagcagag atcatcaaac taatcatccg agatgaatct
    11281 gtacatggaa cctacatcgg ttacaaattc caattaggat tcaacgagtt acctgaagca
    11341 gaacaagaaa cgttaaaaga ctggatgtac aatcttcttt atgagcttta cgaaaacgaa
    11401 gaacgttata cagaagaatt atacgatcca atcggctgga cagaagaagt caagacattc
    11461 ctacgctata atgccaacaa agcattgatg aacctaggga tggatccact ctttccagat
    11521 actgccaatg atgtcaaccc aatcgtaatg aacgggattt caacaggcac aagcaaccat
    11581 gacttcttct cacaagtcgg aaacggctat ttgttaggtc atgtagaagc gatgaaagac
    11641 gacgattatt tgattggatt ggaataagga tttattttaa ttcaaaaatt tttcgaaaaa
    11701 taaaaagagt ttagcgtaca gatattttaa atgtacactg aactcttttt tatgcttatt
    11761 cacttgtttc ttccagcact tttggactgt ctaacttttc cgaaacatgt tccattcttc
    11821 tcaataaata gattttccgg atatttaata ttatcgtctt aatcactgca tagacaggta
    11881 tgcaaatcag catgcctaat attcctgcga cacttcctgc tccaatcaat accaagatga
    11941 tcgtcaaagg atggatattc attgatttcc caaataacaa cggcttgatc aaatttccat
    12001 ctaattgttg gatcactaaa atcgacaacg ccatatacaa agcttgaaat ggagagataa
    12061 acaaaccgac aatgattgct ggtaccgctc caataaaagg gccgacatac gggataatat
    12121 tcgtgattcc gcaaatgacc gcaagcaaca agctataagg ctgatcgaat attctcattg
    12181 ccaaaaagct cattacacca ataatcaaag catctaagat cgtactgctg atataggcag
    12241 ataatgtttc gtttaattct tttaccgttt ggcgtaactc tttacgaatc gctttcggaa
    12301 agaagtgaga caacgcatca ataaatttgt gcccatcctt gaacataaat agcaaaataa
    12361 atggaacggt aaataacaaa ataaaaaatt gcatcataaa tgaaatgatt tttgagacac
    12421 ttgcagataa actgactaat atgatattga acaaattact aagagataaa tttgctgatg
    12481 ctaattgttc ttccaaattg aaatttttaa actcttcccg ctgcgccaat tcatttaacc
    12541 atttgcttgt ttcatctgca tacattggca agctctgggt caattgaatt gtctgttcca
    12601 ttaactgagg cactacattc atgacagtta aaacaactaa aatgattacg accaaaaacg
    12661 tcaataaaaa accgaacact ctcgggatcc gatgcttttc gagaaaaaca acgattggat
    12721 cgaacatata atagataaaa ccagcaacaa gcaatggtaa aaaaattgcc gaaagcattt
    12781 tcaatattgg actaaaaata ttcggcattt gtaaaataaa gtacacgccg atgatcgtga
    12841 gtactagctc cactgtccag aaaaataatt ttgattgttt aaaacgtgat tgcatacatc
    12901 tcctccaagg tcctttgata cttctattct atcatttaac aaagagttac gcgctgagat
    12961 tttcatttgc ttaaaaaaaa caaaaaaaat aaacatattt taatgagtag acgagtactt
    13021 aaacaaaaac acggtttgga gtagtgacaa aaattatact gcagtccctt tttccaaata
    13081 aacggtgttc aaaagcttgc atcttcgtaa taagcccagc caaacgaaaa atataaggaa
    13141 ctatttttat ttggctgggc ttattacttg atgtaggaca tctattttac aacctcagat
    13201 catttattgc gcaatactga ctaaatgcaa ctttgtgata tttttgtgta cggacaactc
    13261 ctcgatcaca tcggcataag tgagcccttt tggaagatca atcgtataga tatttttgta
    13321 cactcggtag tcatcaacga attttacgtc aaaattcaca tcttcgatta cgatattttt
    13381 ctcttcaaaa taatcggtaa gaaaatcttt ggtttctttt ctatggataa attggatttc
    13441 taacttttta gtcgtaggta catggatcac gcgtttcact actgtgagtg caatagcaat
    13501 cccgataaaa ctgatgatcg caatggaata gtaacccatg ccgatggcga tccctaatcc
    13561 agcaattgcc cataaagaag cggcagtcgt aagtcccgtc accgattgtt tcgtgacgat
    13621 gatcgttccc gcgcctaaga aaccgacacc actcaccact tgagcaatca gccttgcttc
    13681 atctgaacga atcgttccag caagctgtgg atactctaaa gcatctctta atgcaccact
    13741 agcgatctca acttggatca atgcaatgat acatgctccc atacaaacta aaatatgcgt
    13801 acgcatacct gctggacgat ttttatattg tcgttcaaaa ccgattgctc cgccaaatag
    13861 catagcgatc cctaaacgta aaataatctc tggaattgtc aataccatat cattcatcta
    13921 aacaccctcc agtccaatat atcatgtctg aaaggagcag acaaaaaaag tgcaattttt
    13981 acctcttacg aaaaaaggac tgtgacaaaa tttttgtcat agtccttttt atgaataaac
    14041 ggtgttcaat cagctgaccc tcggtattac tcaacaaacg gcaaaatatg gggagctatt
    14101 tttcctttgt cttctctaat actcaggtca aaacgctgat ttcacaacct ctttagccta
    14161 ctattgaaaa ttacaactta cttgctgctt cttcatcgat gatcacaaca acattgtcgt
    14221 gattttgcaa tacacttgct ggcaaatgat tcgttacagg tccttcaatc atccctttga
    14281 ttgcatcagc tttgctttcg ccaaatgcca tcaagacgat ttctttactt ttcataattg
    14341 aaccgattcc cattgaaaca gcttttgttg gtacatcttc tgctttatcg aagaatcgtt
    14401 tgtttgcatt gattgttgat tctgttaagt caactactga agtcgttccg tcaaatgaag
    14461 caccaggttc attgaaaccg atatgtccat tttgcccgat tcctaagatt tggatatcga
    14521 ttggatgtgc atcgatgatt tgatcatact ttttgcatgc tgcttccaga tcttctgctt
    14581 ttccatctgg tacaaacgtt tctttgaatg gttttttatc aaataattgg acatccatga
    14641 aatgacggta gctttgttca tctgaaccgc ctagtccaac gtactcatct aagtttacag
    14701 aagtcatttc actgaaatcc aaatcgcttg aagtcatttc tttatataaa gtaactggtg
    14761 tgcttcctgt tgccaatcct aatacttttg cacctttgtt cataccttct ttgatgattt
    14821 caaatgcttt ttttccgcct tcttcagcgt tttttacacg aatgatttcc atagtgattg
    14881 ctcctttata ttttggtata gcccaattat agcattcttt ttttcttttt acaataatta
    14941 gtatagacca aattgcattt ttttcatttt cttgacaata aataggaatc cgtgttaggt
    15001 ttcataagat ggttcaatca aacaatccat gttgcatgaa aaccaagcaa gtgattcact
    15061 gtggacgctt tatgtctgca gtttttttat gaaaaaggag ttattatgag tatactgaca
    15121 ttaaacaaca ttacccagca atttggcgac aaaatcctct atgaaggtgt cgatctgcaa
    15181 ttaaatgctg gcgaacatct tgggctgatt ggacaaaacg gagccggtaa aagtacattg
    15241 attaaaatca tcactggtga gatcttacca gatgacggac agatccattg gcaaaaaaat
    15301 attcacaaag gttacctcga tcaatatgtg gaagtcgatg aaacattaac aatcgaagaa
    15361 tttctaaaaa ctgcgtacgc aaaagaatac gaaaaggaag aaaaaattgc ttttctttac
    15421 caaacatata gcgagacctt cgatgattcc ttgctggaaa aagctgggaa actccaaacg
    15481 gaattagacc aaggagtgtt ttatcaaatc gacaccttag ttgctgagat gagcagcggg
    15541 ttggggatcg atgtcttagg tttagattca ctgttgaaaa atctaagtgg tggacaacgt
    15601 tcaaaggtga ttttagcaaa actactttta gaaaacccag atgttctgat cttagatgaa
    15661 ccaaccaatc acttagatga tcagcatatc caatggctga cgcagtttct tcaggatttt
    15721 gacggtgcgt atatcgtgat ttcccatgac caagaatttc ttgatcagat caccacccat
    15781 atcgcagaca tcgagtttgg aaagattact aagtatactg gccatctaaa acaagcattg
    15841 aaacaaaagg aacaaaatcg cgaaagctat ttgcgccaat atcatgctca acaaaaacaa
    15901 atcgaaaaga ccgaagctta tattcgaaaa tacaaagccg gttcccgatc aacgatggca
    15961 aaaagccgac aaaaacaatt agataaaatc gaacggctga cgcctccagc ttcagcaagt
    16021 aaagctgtct ttgattttcc attctcgcct attgtcacga cattagcagt ggaaacaact
    16081 gatttagtca tcggatatga tcgaccgcta cttgcaccca tcaatttgac catccgcttt
    16141 ggtgaaaata ttgccattcg aggcttcaac gggattggaa aatctacttt attaaaaaca
    16201 ctgatcggtg agattgaaaa aataagtggc gatttccact tcccagataa cacaaaaatc
    16261 aattactttt cacaagatct gtactgggaa aatccattag aaacaccact acaatattta
    16321 agcagtcaat ttccaaaagc gactatcaaa gaattacgtc gccaactagc taaagcaggg
    16381 ttagttaatc aattagcaag tgaacctctc actacattaa gtggtgggga acaaactaag
    16441 gtgaaacttg cacagttgac aatgaaccaa ggtaatttac tgattctcga tgaaccgacg
    16501 aaccatatcg atcaagaaac gaaagaaagc ttacaagacg ggatacagaa atttccagga
    16561 acagtaatca tcgtctctca tgaacaagaa ttttatcaag atcttgtgca acgagtcatt
    16621 gagattgaac caaaataaac gtttgattga atagttgaaa aaaaggagct gtgacaaaag
    16681 ttttgtcaca actccttctt ctgaataaat ggtggccaat tagctgacct tcggtattag
    16741 ctcaaaaaac ggcaaaatat gaggagctat ttttatttgg ctattcttat tacttgatgc
    16801 agaacagctt ttcacaacct cttttcgtct attttttatt ttcgagattt ctctttcctt
    16861 taaaaacaac tgtttgaaag aagaacgcac atccttgaaa aacaagcccg ctaaccgtta
    16921 cacctaacca gccatactgc tgccacattg tcgtccctag caatgaacca gccgcacctc
    16981 caataaagta cataaacata aataca
//
LOCUS       DADQDV010000062        16511 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.064, whole genome shotgun sequence.
ACCESSION   DADQDV010000062 DADQDV010000000
VERSION     DADQDV010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16511)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16511)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16511
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.064"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..546
                     /locus_tag="J8S10_002211"
     CDS             <1..546
                     /locus_tag="J8S10_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HAZ9630791.1"
                     /translation="IHRRFYTSICHQKITTDTTEFKYHEVDAKGIIRQKKLYLDPFMD
                     MFNSEILSYRISEKPNALAVMEGLEEAIQTTNDCPYRRTFHSDQGWAYQMKAYRNKLK
                     EYKIFQSMSRKGNCLDNSLMENFFGLLKQEIFHGKVYNCFEELKSAIDSYIYYYNNER
                     IKQKLNWQSLVQFRKTTVTVV"
     gene            735..1403
                     /locus_tag="J8S10_002212"
     CDS             735..1403
                     /locus_tag="J8S10_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HAZ9630792.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
     gene            complement(1603..1833)
                     /locus_tag="J8S10_002213"
     CDS             complement(1603..1833)
                     /locus_tag="J8S10_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630793.1"
                     /translation="MTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGE
                     AYEDYFMIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(1960..3342)
                     /locus_tag="J8S10_002214"
     CDS             complement(1960..3342)
                     /locus_tag="J8S10_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HAZ9630794.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            complement(3498..4685)
                     /locus_tag="J8S10_002215"
     CDS             complement(3498..4685)
                     /locus_tag="J8S10_002215"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HAZ9630795.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            complement(4692..5723)
                     /locus_tag="J8S10_002216"
     CDS             complement(4692..5723)
                     /locus_tag="J8S10_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HAZ9630796.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            complement(5769..7193)
                     /locus_tag="J8S10_002217"
     CDS             complement(5769..7193)
                     /locus_tag="J8S10_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAZ9630797.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANAATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMED"
     gene            7368..8273
                     /locus_tag="J8S10_002218"
     CDS             7368..8273
                     /locus_tag="J8S10_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAZ9630798.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            8364..9041
                     /locus_tag="J8S10_002219"
     CDS             8364..9041
                     /locus_tag="J8S10_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAZ9630799.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            9322..10218
                     /locus_tag="J8S10_002220"
     CDS             9322..10218
                     /locus_tag="J8S10_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAZ9630800.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(10273..11643)
                     /locus_tag="J8S10_002221"
     CDS             complement(10273..11643)
                     /locus_tag="J8S10_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAZ9630801.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            11881..12627
                     /locus_tag="J8S10_002222"
     CDS             11881..12627
                     /locus_tag="J8S10_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HAZ9630802.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            12624..13463
                     /locus_tag="J8S10_002223"
     CDS             12624..13463
                     /locus_tag="J8S10_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HAZ9630803.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            13464..14414
                     /locus_tag="J8S10_002224"
     CDS             13464..14414
                     /locus_tag="J8S10_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HAZ9630804.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            14555..15307
                     /locus_tag="J8S10_002225"
     CDS             14555..15307
                     /locus_tag="J8S10_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630805.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            15326..16477
                     /gene="queG"
                     /locus_tag="J8S10_002226"
     CDS             15326..16477
                     /gene="queG"
                     /locus_tag="J8S10_002226"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HAZ9630806.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
BASE COUNT         5371 a         3087 c         3319 g         4734 t
ORIGIN      
        1 atccatcgtc gtttctacac cagtatctgc catcagaaaa tcacgacgga tacaactgaa
       61 tttaaatacc atgaagtgga tgccaaaggc attatccgtc aaaagaaatt gtatctagat
      121 ccttttatgg atatgttcaa tagtgagatt ttatcctatc gtatctctga aaagcccaat
      181 gcattagcgg taatggaagg tttggaggaa gctatccaga ccactaacga ttgtccctat
      241 cgtcgtacgt ttcactcaga tcaaggttgg gcgtatcaaa tgaaagctta tagaaacaaa
      301 ttgaaggagt acaaaatctt tcaaagcatg tctcggaaag ggaactgctt agataattca
      361 cttatggaga atttttttgg cttattaaaa caagagattt ttcacgggaa agtttataac
      421 tgtttcgagg aattaaaatc agccatcgat agctatatct attactacaa taatgaacgg
      481 ataaaacaga aattaaactg gcaaagtctc gtccaatttc gtaaaacaac cgtaacggtt
      541 gtgtaaaaat atcattttag agcataaaaa aaaggagtgg atttctccac tccaaaaaag
      601 tctaactttt gggggtcact acagtgtcac agtccttttt ttagtaaaag gatacatttc
      661 ttccttgtat attccatgcg tgttcgtgag aaagcatata taatttaatt aacagatagt
      721 tagggggaga aaaaatgatt ttttcaatta caatgaaact ggtgttcggg ttgatcggtt
      781 tattattagt ggtacgtttg cttgggaaga aatccatgtc agaaatcaca ccgtttgatt
      841 tagtctatac gcttgtttta ggtgggatct tagaagaatc aacctatgat gacaatgtcc
      901 atgtagggca tgtcctattt gccattgcgc tttgggcagt aatgatttat ggtatcgaac
      961 gtatcgtcca aaaaaatgaa aaggtcaatc gttgggtcaa aggcgagcca tctgttctaa
     1021 tcaaagacgg cgtcatcaac atgacagagt tgacaaataa ccatatcgag atggagcagt
     1081 tgcgagcaat cttaagacag caagaatgct tttttcttga aaatgccaaa catgttatcc
     1141 tagagaatgc cggtcaaatg agtgtattga aaaaatcaga tgaagacaaa gctttatcga
     1201 tcctgcttgt agatgaaggg caaattcagc ataaagtgct tcagtccaat caattgactg
     1261 aagcatggct tatggagaac ttgaagaaag aaggctatgc agatgtaaaa cagctgattt
     1321 atgttgaatg gtcagaagaa aaagggctct acatactaaa taaagaagac gtcatgcatg
     1381 aatcttaccg aatagatgga tagatagaca gaggttgtga aatcagcgcc ttggcttgtt
     1441 actcaaaact aagcgacttt ttcacaacct ctgatatcta atatacgttg ttccagaagt
     1501 tgcttcttcg aaaaataagc caaaattcca caaaaattta agaagcaatt ttcgaaaaat
     1561 cctttcttat tttttgaagt tgatcacttc tgtcacaacc tctcatgtca caaaccattt
     1621 ttttgtttcc tttaactcaa tataccgtac gtcttcccac aatatcggct gatggtcaat
     1681 cataaagtaa tcttcatagg cttcaccaat gaagtgccct tcgacctcat ccaagagtct
     1741 tccaaattca tcttttaaat tgagctgaat gattactgct ttacgagata aaaaggcttc
     1801 tgtcagtata ctatcgattt cttgcaatgt catttgttgt ttaggaagag gctgtttgcg
     1861 tgcttcttct tcattttttt gataccgttg actagttctt ccatcgcaaa agcagtcccc
     1921 cattttaatc caaatggccg atctcgatac tcgttatagt caatgaattt ttttgctgtc
     1981 cgtctcatct tttccacctt ctaatccact cataccacct gcatgcccgc caacgagaga
     2041 actacgtgcg atggcgcgtc ctccttgcaa gagactatgc gcatggatga ttgattgaaa
     2101 gccgtatttt tttctaatcg tatcgacaac aaaatcaact ttcgcttcat ttatctgctt
     2161 ttcaggatct tcaaaaaggt taagctgtaa acctgtcgcg tatacgaggt cggaacagtt
     2221 cacgcctaca cgccgaatat cctggtagtg gtaatgctgg tggaaaatgg tcaataaagc
     2281 atctgcaaga tctctgctag catttgtcgc ttcgattttc atttgctggt gaaacccggt
     2341 cttgccattt ggatcaagat agcctaaaga gtatcctacc cataagctga ctacttgtgt
     2401 ttttgctgca gatcgtctca agcgagtgcc gacttggtcg gccatttctt tgataacgat
     2461 ctcgatttct tctcgtcttg tataatctct atctaggatt tgactatttc cgatactttt
     2521 tgattttggt gtatattctt gtcccaaaaa acttcgatcg atgccccaag catgggcata
     2581 aagctgagta ccgatgaccc ctagcttgct tttcaagtga taataatccg cgtgagctaa
     2641 atcataaaca gaatgtatac ccatttgttt cagacgtttt gctgttcgtt tgccgattcc
     2701 ccaaaagtca gtgatatctg agattttcca taacttttct ggtacatctt cataacgcca
     2761 ttcagcaaac atttgctttc cgtcttttga gccattgtct aaggctagtt tagcaagtag
     2821 cgggttatcg ccaattccta tagtcgtgta gattccggtc tgctcaaaca catctttatg
     2881 gatcagttta gccatgtcgt acgcatttgt tttaccaaag agtgccatgc tatttgttac
     2941 atcaaggaag ctttcatcga cggaatagac atgatggttc gcttcgtctg catatttttt
     3001 atagatagaa ttgatttctc tgttcttttc catataatag gccatccttg gggcaacaat
     3061 atataaatca cttggatagg ggaagggaag atctctggca cggctgatat tggtgatgcc
     3121 gtaagctttt tttgctgcag gactggaagc caagattaat ccgctacccc gtgtttctgt
     3181 cgaatcggac ggataggaca tgactactaa tttagttgta aggggatcaa gatccttttc
     3241 aacgcactct acggaggcgt aaaaagattt gcagtcaata cataaaatat ctcttgaagg
     3301 ttctttttca taaacaaata ccggattttg attcgcccac ataacaatca cctcttcaac
     3361 acaattagaa cacacgttct ctttccgtgt caataaaaaa cagcaatttt caaatacgag
     3421 caaaaggctc acatttggaa attgctgaga ggttattttt atctatttgt ttttagctga
     3481 gatcgttgat ttttttatca aacatgaaca gcttctggat cgatctttgt tgtcccattt
     3541 ccaatgtgtg caacataaaa ttccggagca tagccgacaa ctttcatgta ttcatcatag
     3601 acattgtttt tgaaggcagg tatattttct tctttgacaa gagcaatcgc acagccacca
     3661 aatccagctc ctgtcattcg tgcacctaag acaccttctt gtttttgagc agcatctact
     3721 agtgtatcta attcgatccc agttacttca taatcatagc gaagagagtg gtgagaatca
     3781 tttaacagtt gaccaaatgc ttctaagttc ccagcttcta attcagcttt tgccttcaaa
     3841 gtccgctgat tttcagaaac ggcatggcga gctctgcgta tcaatgtatc atcgccgatt
     3901 tggtcaatag ttgattcaaa ttcttcttca tctaagtctc ctaaagaaga gataggcaaa
     3961 gttttttgca aacgtgccaa ggcttcttcg cattcgctac ggcgttcatt gtattttgaa
     4021 tctgccaatt cccgccgctt attcgtattc atgatgacga ttgcataacc atctagtttc
     4081 actggaacca tttcgtattt cagcgtattt gtatctaata agattgcatg atctagctca
     4141 ccgaagccga tggcaaactg atccatgata cctgaattga caccgatgaa ttcattttct
     4201 acttttttac ctgtttggac tagttccaag cgatctgttt ttaaatcaaa cagatcttct
     4261 aatacaacac ctactaataa ttctaatgaa gcgctactgg aaagtcctgc accattaggg
     4321 attgttcctt ccactaataa ctcaaaccca tgatcgattg agtgtccagc ttcttttaat
     4381 ttaaggacca ttccttttac gtaatttgcc cagtttgctt ttttatcata ttctagctca
     4441 tctaaagtaa aactaatgac accgatatcg tcaaagtttg tggaataaac taatatttta
     4501 ttatcgtctc gaggtgctgc tacaccttgc gttccataag tgatggaagc ggggaagaca
     4561 tggcctccat tgtaatctgt gtgttcacca atcaaattga tgcgtcctgg tgagaagtat
     4621 tgtgtagttt ttttaggtcc gaatgtttcg gcaaattttg tgtttaagct tcttttgatt
     4681 tccatgatga gttattcctt tcttgttttg attttgaatt ctgttactgt ttcaaatact
     4741 gatccggctt ttaaatgaat cgaaccaaat gctgagaagc gctctgcacc tggagctgtt
     4801 tgagtctcaa atgtgatgcc accgtgatgt gccagttttc ggttgcgcat ttctggtgtt
     4861 tctgtgccga aatttgcagt gaaaataacc acactagaag catctgtagc aatatctact
     4921 tggattcttt tatcggggct agtcaagcga gcggcttctt tacccaagcc ggtttctttt
     4981 aagaaaaatg gatgatcgat tccgtcaaca agattttttt gatccaaatc actagcaaaa
     5041 acggacgcta attttttagg tatttgaaaa tcgaaagcac ttcctgcagc attttctttt
     5101 acccctatag gaatactatc tgttcgcaaa ggagcataag cttcgctatt gagccaaagc
     5161 tcatgttgat cgattgactg agaagcatct cccgtcaagt tgaagtaaac atgatttgtc
     5221 ggattgaata aagtatcttg gtcactggtg ccgcgagagg tcactcgcca gatattatct
     5281 tttgtcaaag tatagcggat ttccacatcc attgtacctg gaaaaccatg ttctccgtcg
     5341 ggacttgtag tagtaaaaat gacagaagct tcattttcgc cattcaaaat gacataagac
     5401 cattttttta attcaaatcc aggagcacca ccatgcagat tatgtccagt ttttggatct
     5461 gtggctaatt ggtaagtttt tccattgaga gaaaagcggc cattttcgat tctccctgcg
     5521 gtgcgaccga tagaagcacc gatatacgga tctttttcga tatattcttc agcggtgtca
     5581 aatcccaaaa ctaattctcg atcatttgat tttaaactga cgattctagc acctaaatca
     5641 gagatagaaa gtgctagctt gtttttgttc tccaaggtta tcaagtgata accttggcca
     5701 aaatcttttt ctgtaatctt cattttcaag atcctttctt aatgggaagg aactactgca
     5761 tcgtgaagtt aatcttccat tgtatcagct ggagccaatt tgttttccaa tttctcaacg
     5821 atttgtgcat gttttttctc tgtcaatgta atcttccaag caaaaataat agcggagaaa
     5881 atcatcaaag cagcaggagc atagaatgca taagctttga aagtcgttac gccatgagca
     5941 gtgatatcag cagcagtagc attaccagtc atcccagaag cgatagcgac aaaccctacg
     6001 atcccgttag acaaagcacc agcgatttta tctagtaaag ggcgaattga tagagtaaca
     6061 gcttcgttac ggataccatt tttccattga ccatattcaa cagagtctgt gatcgtcatc
     6121 aaagcggata agaaaatcaa ttgttgaggg aagtagaaca atactagccc gatgataacg
     6181 attggcaaac ttgaacctgc gatcgtaaag aaaaagtaag aagaaatcat cattgcgatc
     6241 cctccaaggt aaacgtagcg acgagagatg acgcgtgtaa gcattgggaa tagtggaaca
     6301 gctactaaac caagtaaggc agcaactaga ccaacgatcc aaaattcagt tggttggcca
     6361 agtacatatt tgaagaagta gaataatacg gcagttgttg ctgcattggc aatcgcataa
     6421 gcgatataag caagggcaag ccacatcaac tgatcatttt gagcaactgc tttgaacaca
     6481 tctttgatcc cagctttttc attttgctga cggatcgcag tatcgacttc ttttgtgccc
     6541 aaggcagtga taatcgcagt accgcctgaa ataacagcag caatcacacc gaaccagaac
     6601 cagcctgaag cgccttcaat atgtttatga gtaacaagat aggtaaagaa agtaacgata
     6661 gggacaacga ctagagtagt accatttgca cctagagaag agccgaaacg agcaaacgta
     6721 gcaaattttt cacgttcctt tgtttccgta ctcaaagctg gaatcattga ccaaaaagcg
     6781 atatccttaa atgaataaaa actatccaat aagatgaaaa cgattgcaaa taatatgata
     6841 aataaagtcg tattatgagt agctaagcca aagaaattgg taaagattgc taccaagagt
     6901 acggaactaa caacgccgcc gataactaac catggtttga atttaccgta ttttgtacga
     6961 gtattatcga tgatgccacc aatcaaagga tcaaaaataa tttcaactaa gcggatacct
     7021 acaactaagc ttgtaactgt agcaatcatt tttgcattcg ttgccttatc tgttcctgcg
     7081 aacatctggc ttgtcacgaa taccataaaa taagtgctta atgtaacata gaatgtgtcg
     7141 tgtccaaaag cgcctaaagc gtaggacaca cgttggatca ttttgctttt cataatctgt
     7201 attcctctcc tgttcaatat ataatactaa gtaaaccggt tacaacgaat aacaaagatc
     7261 ttttaatgac ttaaacttaa caagaaatcg cttccttttt aatatatttc tgtgactttt
     7321 atttaacttt ttgttgcatt atactaaagg agtaaggagg gatagacgtg gagcaatcga
     7381 tttttttaaa aaaggaacat caacaagtag aaaaagaatt gtattttgat ttttgtggtt
     7441 tctctaaaac gatgccgttt cattcttttg gtcctgctat tcgcaatgat tacatcctgc
     7501 atgtcgtgat ggaaggcaaa ggatcttatc atgtgaaaaa tcaacaattc caattgaaaa
     7561 aaggtgatct gttcttgatt cgtccaggag actcgacgtt ttacttatca gatggagaag
     7621 atccgtggat gtattgctgg ctttcatttg gtgggagtgc tgcagaagaa atcattcggc
     7681 agtcgctttt cagagaagac caatacacga tggtctcttc tgacatacaa aaatatatcg
     7741 acattatttt agaatgcatg aaagatacgg aagaaacctt ggaaaatgaa ttacagttaa
     7801 cagcattaac ctaccgtttt ttatcagtcc ttttaaaaga tggcggaaag gtcagcggtg
     7861 gtgtacaaaa ggttcattcc tctttagctg ttgaaacagt caaatacatc gaggcacatt
     7921 atgctgaaaa attgtctgtt gaggaaatcg cccagcattt agcggtcaat cggagccatt
     7981 tgtcgcgagt attcaaaaat catatgggta ccagtatcaa ggaatatttg atcggggtac
     8041 ggatcaatcg aggggcgttt cttctttctc tgacggatga atccgtggaa agtattgcct
     8101 atcaagtagg gttcaatagt ctagtcgtat ttagccgaat gttcaaaaag agtaccggag
     8161 aaacggctac gaactatcgt aaacgtatga aaaacgaaaa ttttaagaat attgctttgg
     8221 ataccttgaa aaaacagttg gaaaaacaaa ccgcagtttc ttggacaacc tgattagtct
     8281 ggttaaaatg acaagcatcg gcaaaagaaa cttgtggcgg ttatgctaca ctgtaaagcg
     8341 aagactaaaa aggaggaaaa gggatgcgta cacttatcat cattagccat ccaacgatcg
     8401 aagaatcttt aaatcagcaa tttttcaaag aagcttctgc tggtttacca gctacttggc
     8461 atcatttgga atcaagttat ccagacggaa aaatagatat agagactgaa ctacagctct
     8521 tggcccagca tgatcggatc attttccagt ttccgtttta ctggtatagt tctcctgctc
     8581 atttaaaaat ttggcaagat aatgtcttgg aacgagcagc acatgtatta aaagggaaag
     8641 aactaggaat cgtattgaca acaggtgtgg cggaaaaaga ataccaagct ggaggaaaag
     8701 aagaatatac gatttccgaa tttttgaggc cgtatcagcg aatcgcaaat aaattccata
     8761 tgacctatct tccgccattc gttttagcac aatttatgta tttatcccag gaaaaacgtt
     8821 gggagaagct aattgcttat cagcagtatc tctcattgga aggcaaacca tcgctgactc
     8881 agcggattga ctggtttatt caaagagtac aggaaaatca gaaaatgcag gaagaagaat
     8941 ctgaaaaaca agcatatatc gtagaagcac tgactgaggc aaaagagcag atcgaagact
     9001 tgacctttac actgcaagaa atgaaaggaa cttcattatg acaaatgatt ggctgatcca
     9061 acaattagat gaattaagcg aaaaatcaga atatcaagac cgtgcgctct tatatgaaat
     9121 aaagaaactg atggctgaga tagacgaacg aacaatgcag ctgcaaggag aaatcgacgg
     9181 acaatcttgg aatcatctca actggtgaaa ttttcttata aataacaaag ataaaaatgt
     9241 gcacagcgac aattatttgc tacaataaga atatgaagcg tttgataacg ctattataca
     9301 taaaaattgg tggtgaaaaa aatgtatgat gaaaatgagt ggggagaaaa tgttcggatg
     9361 acccgaagaa gacagcaaaa acaggcagct cgtaagcgga tgatcatgat tggggcagca
     9421 gttgccgtgt ttttgatcat agcaggagga gttgcgggtc tatattttca tggaaaaaat
     9481 tcgtcagaag cgaaaagtac gaccataacg gaaacaacga caaagaaaac agagacgaaa
     9541 caaacaagtg agtcatcaac taaaacaaaa gagacacaaa cttctgaaga aaaaacagca
     9601 aatggtttgc cagagcaact tcaagcaatc gtaaatgatt attcgaaaaa gatcgaagaa
     9661 aagacgcctg cattgattga agaataccag acagaaattc agggaaatca agagggaata
     9721 gctggtttat cagcagttgc taaccaaaaa gcacgtgagc ttcaagcaat ctccgacgaa
     9781 gggatcagaa aattacgtgc agcgtatcag gcagcagaaa ataaagacgg tgtagactta
     9841 gatactttga tcaatcaatt atcggctaat tatacgaatc atgtcgctaa gatttccgat
     9901 atttatttgc agactagcgc ctctcttcaa gcagagtcaa caagcacaca agacacaaca
     9961 tcttctgatt ctgagacagc agagtcggta gaagcttctg aaatgcaagc tcgaacaaca
    10021 caagacacaa cagattcctc tgaaactaat accaacagcg cgacttcaca ggctgcgaca
    10081 accgtagttt tggaaggaga aggtccaaat caaatagccg aacgaactgg cgtaccagta
    10141 gaaacgatct tgtcgctgaa tgggatgagc atggagaatt atttcctgac tcccggtgag
    10201 acgctaaaat tgaattgata aaagcaataa aaaagaacga agcttccact aaggtgaagc
    10261 ttcgttcttt ttttattttc cggttctttt ttcgcgtaca aagtaatgga tcgtcatgta
    10321 aagcaagaaa acgagtccaa taatcaatga gattctcgtt tcaggattga taaacatgaa
    10381 aatcaatacg atagctaaaa aagcaagtgt cacataattc gtataaggag atagtggcat
    10441 tttaaaagga tgatcatgca ttttatctgc gtgcttcttt ttgaagcgaa tctcgctgat
    10501 caaaatcact acccaaggaa ccataccagg caaaatactt gagctgtata cgaaaacgaa
    10561 aatattttct gactggttga tgaacattgg tagaagataa tttaagatca gaccaattaa
    10621 gattccacct gagattgcta cgacaggata aaaaggcgca ccgtgacgag atagtttcag
    10681 aaatttttta gacatctttc catttatggc aagtgtatag accatacgac ttgcgctgaa
    10741 aatccctgaa ttgcaacctg ataatgccgc tgtaatcacg acaaaattaa tcagtcctgc
    10801 agcaaatgta atgccgactt tagaaaaagt ttgtacaaaa ggtgaaccaa tctcactcaa
    10861 ttgattccac ggatagatac tcacaatgat aaaaatagca ccaatataaa aaatcaagat
    10921 tcgaccgata gtggactgga cagcttcaat gatcgtcttt ttaggattct ctgcttcacc
    10981 agcagtcatt ccgatcagtt cgattccttg ataggaagca acaacgatcg ataatgcaaa
    11041 gaaaaatcct ttgacgcctc cagtgaagaa tccaccattt ttccaaagat ttgaaatccc
    11101 tactgcctga ccatgattac caaatccaaa taagattacc ccaagacctg caatgatcat
    11161 caaaatgatc gttatgactt tgatgatcga aaaccaaaat tctaattcgc caaacgcctt
    11221 gacagaaata agatttgcca gcataagaaa caagacgaca atgattccgg gaataattgc
    11281 cggcaaatca ggccaccaat aattcatata agatcctaca gcaatcactt cacttattcc
    11341 tacgacaata tattgaaaaa tattactcca agcggtcaag tagccagcca caggatggat
    11401 gtactcgctc gcgtaatttg caaaagaacc agtcgaagga tcaacgtaaa gcatttcgcc
    11461 taaagcacgc ataatcaaat acaaaaagaa tcctgcaatc gcataggctc ccatcactga
    11521 gggccctgtc caacgtatgg ttgaggaggc acccataaac agaccgacac cgatcgttcc
    11581 acctagtgcg atcatttgga tatgacgggc actaagactt cgagttaact tttcttcttc
    11641 catacaaaaa ctcctttcgt tgttgagtca acaagaaaaa ataatcaaac gtttcaacac
    11701 atgtttttca ttattaggtt agccttattg aactcttgat gtgattctac agaaaatttt
    11761 cataaaatgc gaggaaaatt cgaaaaaaac tttttcatca ttctacttga aaatgctttc
    11821 cattttagtt aaactatatt taaataaaaa gttaggtaaa cctaaaaagg agtgtaagat
    11881 ttggaacgta cggccattgt aattcaagac ctttcagccg cttatcaagg gaaaactgtt
    11941 ttgaaaacta tcaacttgac gataaatcca caaaaaatta ccggtattat cggaccaaac
    12001 ggtgcaggaa aatcaacatt tatgaaatct ttgctagagt tgataccagc tactactggt
    12061 aaagtcacct tttctggaca gtcggtaaac tcagtccgta aaaaaatagc ctacgtggaa
    12121 cagcgaagtg aattggatct ttcctttcca attgatgtat taggcgttgt acttttagga
    12181 acatatccat ctttacgaat tggacaaaga cctgggaaaa aagaaaaaga acgtgcaaga
    12241 caagctttga aaaaagtagg gatggaagaa tatgccaaaa gacagatcag cgaactatcg
    12301 ggtggacagc ttcagagagt ttttattgca agagctctag cccaaggagc agaatggatc
    12361 tttttagatg aaccattcgt agggattgat gcgttaagtg aacgaaagat ctttgacatc
    12421 ttgcaggaat tgaagaattc aggaaaaacg attttgatcg tccatcatga tcttcataaa
    12481 gtagaagaat atttcgatga ggttattctt ttaaataaac agctgatcgc ttccggtcca
    12541 gtacaagaag tctttacatc gaagaacctt caattggcct atggtgagat catcagacat
    12601 ttagtaaaag gaggagagaa aaaatgatcc aatcctttat tgatggatta atgaattatc
    12661 aattcctgca atacgctttg gtcacttcca tgcttgtagg acttgcttct ggagtcatcg
    12721 gttcttttat tattttacga gggatgtctt tgatgggaga cgctatctct cacgcagttc
    12781 ttccaggtgt agccatttct tatatgtttg gttttagtta catctttgga gccactgctt
    12841 ttgggatgct aacagcagca gtgattggtt tcgtgactca gcggagccga ttgaaaaatg
    12901 atacagcgat tggaattgtc tttagctcct tttttgcatt agggattatc ttgatttcat
    12961 atgcccagag tgcgacagat ttgtatcata ttttatttgg gaatgtctta gctgttaggg
    13021 aaagcgattt gttgctgaca gcactcgtta gtggaatcgt cttgatattt gtctttttct
    13081 tttataaaga attgaagatc acatcattcg atccgacaat ggcaaaagct tatgggctga
    13141 acacatcgct gatccattat cttttgatgt tctttttgac attagtggct gtagtcagtt
    13201 tacagacagt aggaacaatc ttggtgattg ccatgttgat cacaccagcc gccacggctt
    13261 acttgctaac gaaccattta ctgaaaatga tcattacagc tgcaggaatc ggtatgctaa
    13321 gtgcagttgt cggtgtgttt ttcagttata gttacaattg gccatcagga gctacgatcg
    13381 tgttagcatg taccgcattt tttatccttg cttttttatt ttctccaaca aaaggaattt
    13441 tatttcagaa aggaagcaga tagatgaaaa caaaaaaatc actcttttta atcttggcag
    13501 ttagtttctt ggtattagcc ggttgcggaa agcaggcttc tgaccaagcg gatgaaggaa
    13561 gtaaagaaaa gttgtcagtc gtggctacca attcgatctt ggcggacatg gcaaaagagg
    13621 tcggaacaga tcaaatagat atccacagta tcgtaccagt cggaacagat ccgcatgaat
    13681 atgaagtact accagaagac atcaaaaagg caagcgatgc agatgttatt ttatacaacg
    13741 gtttgaatct tgaaacaggt aacagctggt tcgataactt gatggaaacg gctaaaaaag
    13801 aagaaggaaa agattatttt gcagttagca aaaatgtaga acctctttat ttaactagcg
    13861 gtgaagaaca tacaaaagca gatccccatg cttggctaga cctatctaac ggaataaaat
    13921 atgtggagga aatcgcacgt atattctctg aaaaagatgc agaaaatgcg acactctata
    13981 aaaaaaatgc agaagcatat gtggaaaaac taaaagaatt agatacacaa gcgaaggaaa
    14041 gttttgcttc tatcgaagag aacaaaaaat tattagtaac aagtgaaggg gcattcaagt
    14101 atttttcacg agcatatgat ttgccagcag cttatatatg ggagatcaat acagaaagtc
    14161 aaggtacgcc tgatcaaatg aaagcgatca ttgatcagat aagagcaaaa gaagtaccgg
    14221 ttttattcgt ggaaaccagt gtagactcaa gaagcatgga acgggtagca aaagaaacgg
    14281 gtttgaaaat ctatgataaa ctgttcactg attccatagc aaaagaagga gaacaaggag
    14341 attcttacta tcagatgatg aaatggaata ttgaaacgat ccatgaaggt ttgtcacaaa
    14401 caaaagaaag ctgaaaagtg caaggtctag cttgaggagc agaccttgca ttttttataa
    14461 gagatatgaa aaaaaattat gctgtttttc gtcgtacaga tacctttttt gaagaaattc
    14521 cgttatagtt agagtaagga aggaaggtgt ggctatgaat tttacacgta aagataaata
    14581 tacgattaaa gaagaagtct ttcgattgat cagccagcag gaaaataccg acaaggatca
    14641 agaccttcaa tttcttgaag cagaattagc taaattattc atagcaaatc aaaatgagac
    14701 aacagaacca gatgaagagc tgtacatagg caaatggttg tttgatgaat ttcagccttt
    14761 agatgaaaat accggtatcg gttattttgt gttcctttct ccagtcggct tcacacctgg
    14821 cgtattagtt aaacaaaacg acgaaataac cgtcaaagca tggcctgcat tattttcagt
    14881 catcaaagca gaaggagtaa tcaaaaagat ccagtcggcc tattataaaa gtcaatttat
    14941 tgccaacagc aaattaatga atatgtttta taatcgtcta gtagaaattg ctaggcctgg
    15001 gaaaatcccg caaacattca cgtacacaca gcaaaaaaat ctctatgaag aagtattgta
    15061 ttcccgcgat ctgtctgagt tttcgccatg ggaagaggta aggctccatg aactgttaag
    15121 tacaaaacca gtttcattga atttttttaa tgcattagat aacaaaagaa aattaatttc
    15181 aacaaattat tgggaagtat ttgctgcaag aaaaaaatgg atggaagaaa agaagattgc
    15241 cgatcagcag atccagtttg tccagctgaa aaaagaaaaa ctatattatg ggttatacag
    15301 ccgttaacag caagcgagga agaccatgac attaaaagaa gaaatcatac aagaaagcaa
    15361 acgattagga attgacaaaa tcgggttcac cacggcggaa ccttttgatt cattaaaaga
    15421 atcgttggaa gaacaaaaag cagctggcca tacttctggc tttgaacatc caaatatcga
    15481 tgagcgtctt tatccagaaa tgacatttga tcagccgaaa tcgatcattt ccattgcact
    15541 tgcgtatcct actaggatcc atgaagaagt gcctagggat gaaaaacgcg ggcagtttgc
    15601 tcgtgcttct tgggggatcg attaccatga tatactcaga gaccgtttga accgattgat
    15661 cgaattcatc caaacaagag cagaaaaatg gcaaaaagaa gaggaatggc gtctagctcc
    15721 gcaagtagat actggagaac tgatcgatgt cgctgtagca cagcgagctg gtttaggatt
    15781 tattggacga aacggattgt tgatcactga agagttcggt tcatttgtct atcttggtga
    15841 gatcgttact aatattgtat ttgagcctga taaaccagga gaatttggtt gcggtgactg
    15901 tatgcgctgc gtgactgctt gtccgacaaa agcattgctt ggtgacggaa gaatgaatgc
    15961 ccagcgatgt ttgtcttatc aaactcagac aaaagggatg atgccggaag aatatcgtaa
    16021 aaaaatgcga aatgtcattt atggatgtga tatctgccag ttagtctgcc cttacaatca
    16081 aggaaaagat tttcattttc atgaagagat ggaaccaaaa gtagacgaaa tatatccaaa
    16141 attaaagcca atgctttcga tgtctaataa agacttcaaa cagcaatttg ggcatttagc
    16201 tggttcatgg cgtgggaaga aacctttgca gagaaacgca ttgattgctt tagctaatct
    16261 aggtgatcga acggcattgc ctgagatttc agaatgttta acagatgtcc gccctgtcat
    16321 cagaggaaca gcagcttggg ctattggacg tctaggaaca aaagaaccgg aaaaatggct
    16381 tgatgtatta gatgaaatat tagctaaaga aacagaagaa gtcgttataa acgaattgga
    16441 acatgcccag aaattattgc ggagaaagtt aaaataaaaa aatagttaac attattcaaa
    16501 gtttttgtcc a
//
LOCUS       DADQDV010000063        15914 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.065, whole genome shotgun sequence.
ACCESSION   DADQDV010000063 DADQDV010000000
VERSION     DADQDV010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15914)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15914)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15914
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.065"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            264..587
                     /locus_tag="J8S10_002227"
     CDS             264..587
                     /locus_tag="J8S10_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HAZ9630807.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            769..2139
                     /locus_tag="J8S10_002228"
     CDS             769..2139
                     /locus_tag="J8S10_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HAZ9630808.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(2269..3570)
                     /locus_tag="J8S10_002229"
     CDS             complement(2269..3570)
                     /locus_tag="J8S10_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HAZ9630809.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYHYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKIE"
     gene            complement(3800..5791)
                     /locus_tag="J8S10_002230"
     CDS             complement(3800..5791)
                     /locus_tag="J8S10_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter Kup"
                     /protein_id="HAZ9630810.1"
                     /translation="MATTHNTKKISMAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGL
                     SGINPDFVIGSVSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLII
                     PAMIGGAALLADGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFM
                     VQRFGTDIVGKAFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKL
                     GLFILGNIFLATTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQN
                     PEAQQIKNLNPFFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPR
                     LKIMYPGNSIGQMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALL
                     YFYLIQNGHSRWLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWE
                     QGNIIRESSTEDVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSI
                     LDKRPKRARVYWFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQ
                     VIHDLMKQGRLPKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAI
                     KKIATSPETWFGLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(5935..6201)
                     /locus_tag="J8S10_002231"
     CDS             complement(5935..6201)
                     /locus_tag="J8S10_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAZ9630811.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(6711..8837)
                     /gene="pnp"
                     /locus_tag="J8S10_002232"
     CDS             complement(6711..8837)
                     /gene="pnp"
                     /locus_tag="J8S10_002232"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HAZ9630812.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(9025..9294)
                     /gene="rpsO"
                     /locus_tag="J8S10_002233"
     CDS             complement(9025..9294)
                     /gene="rpsO"
                     /locus_tag="J8S10_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HAZ9630813.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            9545..10108
                     /locus_tag="J8S10_002234"
     CDS             9545..10108
                     /locus_tag="J8S10_002234"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HAZ9630814.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(10361..10882)
                     /locus_tag="J8S10_002235"
     CDS             complement(10361..10882)
                     /locus_tag="J8S10_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HAZ9630815.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(10885..11727)
                     /locus_tag="J8S10_002236"
     CDS             complement(10885..11727)
                     /locus_tag="J8S10_002236"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HAZ9630816.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(11720..12445)
                     /locus_tag="J8S10_002237"
     CDS             complement(11720..12445)
                     /locus_tag="J8S10_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HAZ9630817.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            12621..12917
                     /locus_tag="J8S10_002238"
     CDS             12621..12917
                     /locus_tag="J8S10_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630818.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            13485..15077
                     /locus_tag="J8S10_002239"
     CDS             13485..15077
                     /locus_tag="J8S10_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750719.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAZ9630819.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            15090..15830
                     /locus_tag="J8S10_002240"
     CDS             15090..15830
                     /locus_tag="J8S10_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAZ9630820.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
BASE COUNT         4556 a         3261 c         3052 g         5045 t
ORIGIN      
        1 atttctaatc gtttattttc atatggggct tccacttttg taaatggctt tacaaacgaa
       61 aaatcctaat ttaccaagct tttcctcgca tacttttatc gtacctttat aaaaatttat
      121 actttgaaaa aaagtattca attattgttg catttttcct gattctttat tagaatgaac
      181 cctcgttgaa gtaagtattt ctagtttatc ctaggattaa ttataaaaat aaaacattcg
      241 ttgattcgaa ggaggttaaa cagatgtttg aaagttttga tagcagccgc aaccgttacg
      301 cttcagttgg tgtcgtatca agtttgccag atgaattgat tgacagtata tggtttatta
      361 ttgacctaga tcttaaggga gtcattccat tagaaaatat attaaccttt gatttgatcg
      421 aaaatcgtgg aaaagtgacg atgcattttt ctcaagcagg aagcaatgtg gaaatggata
      481 ttgatttgcc gtttgcctat tcgaaccaat ttcctgctca agtatacgcc tatgatgacg
      541 gtacgagaga aacgatcctt ttaccaagtg agattagaca atattaaggt gatagataaa
      601 cgtggatgtc ccttatttta cagaccaggc caagttgttg attctttgac tcaattcttg
      661 gcttcttttt atggagtttc ataaattatc attgatttct aattggtatt ctcaggataa
      721 acgctatata ctactaacta aattttaaag atataaggag tttaaaagat gcgcgattta
      781 acaaaaggaa gccccgctaa actgattttg atgttcactg ttcctttact gatcggaaat
      841 gtttttcagc agttctacaa tatgatcgat atgatcatcg tgggtcagac gctaggtaaa
      901 aatgcgctgg cagcggttgg tgcaactgga agcctgacat ttttgatcat tggctttgcc
      961 caaggtttaa cagctggttt agccattatt accgcacaac gttacggtgc aaaagattat
     1021 cggggtctga agaaaagttt tgctgctagt gttgtcatta gtcttgtcgt cactgtgatt
     1081 ttaactgtcc taagtctcct gtttattcgt ccgatgcttc aattgatgca aactcctcct
     1141 gaaatacttg atcaagcaca aacatttatt tcaattattt tattagggat ctttgcatca
     1201 gtcagtttca atttgctttc taatgtcatt cgcgcacttg gtgacagccg cacaccacta
     1261 ttctttctga tcattgcggt catcatcaac gtcgtacttg atttgatctt tattatctat
     1321 tttggcatgg gtgtggaagg tgcagctatt gctacagtaa tcgcacaagt ttcttccagc
     1381 gtactgtgtc tagtgtatat caagaaaaaa atgcctttgt tacagttacg caaaaaagat
     1441 ttcaaatttg aaaaagaaga gtttgctgta cacctaaatg ctgctttgcc aatggcgttt
     1501 caatcttcga tcatcgctgt tggtgctatc gtgttacaag cagcactaaa tagtctaggg
     1561 acagatgtcg tagctgctca agccgctgct ggtcgtatcg accaatttgc aaatcagccg
     1621 atgatgtcat ttggtattgc aatggcaact ttcactgcac aaaactatgg tgcgaaagaa
     1681 tatggccgaa tcttgcaagg ggtacgtcaa actttactga tgagtgtcgg atttagtctc
     1741 ttagcaggtg ctatcgtcat tttcttcggt catttctttg ttcaattgtt tgttagccca
     1801 tcagaaacac gtgtatttga attagcacaa acctacttca atatcaatgg gtctctttac
     1861 tggatcttag cagtcctgtt cattttacgc tacacacttc aagggcttgg acaaagcaag
     1921 atccctacga tcgccggtat gatggaattg cttatgcgtt cttttgcagc tatcgttctt
     1981 acaggaatgt ggggataccc aggagcagca gcagcttctc ctttagcttg gatcggttct
     2041 gttgccgtgt tgctttactc ttatatgcgt tcgatgaaac aattgaaaca catgggtgaa
     2101 gaggaacatt tcacattaga acatgcagaa gcaagatagc cttgattaaa agaaatcgtt
     2161 gcggctaaaa atgaaaactt ttattgaaaa tatcttcttc gtttaccgaa aacaggtttt
     2221 ttagataaca aaaaggctgt gacaaaaaat gtcacagcct tttttctttt attctatttt
     2281 tctttccgtg gactctactt tgaaataatc gatatgtgca tgctggtatt ctaataccgt
     2341 gaaacggaat gatgcaatct caatgattgt tcctgctttt atttctttat atcggctaga
     2401 agcaaagccc gcaagtgtag taaaattcgt ttcttcaaac tctggaatct ctacatgaaa
     2461 ataacgctgg aaatcatcta atgttagttt gccggagatg atataagagc catctgactg
     2521 ttccgctatc aatgcttcgt ccaaatctgt ctcatctcgg atttccccga cgatttcttc
     2581 taaaatatct tcaatcgtca ctaagccgct tgtccctccg tattcatctt ttaagatagc
     2641 aatatgcttt cccttttttc gcatgatcgt caataatttt tttataggga tcgtttcagt
     2701 tgttacgatc ggctcttcaa tcaactgttc tactgtcagc tggtcatctt tataagattg
     2761 cttgatcaaa tctggcaagg tgacataacc taaaacattg tcttttgatt ctaagataac
     2821 cggatagcga gtatgtcctt gttcaatcga agcttttatc gcttctttga cggtttctga
     2881 agcttcgaat acttgcatgg acgtacggtc tacttgtata tcttttgcca aggtatcatc
     2941 aaattcaaac acgttttcca aataatgata ttcttctttg gtcaactctc ctttttcata
     3001 agaattcaat gcgactaatg tcagctcttc ttgagacaat gtctcttctc cttcagatac
     3061 gagacgcaca cctaatagct tccctagccc tgcagctgaa tgattcaata cccaaataaa
     3121 aggaaacatt actttataaa aataatgaag tggtttaact acgaacaaga cgaccttctc
     3181 cgtattgacg atactatagc tcttaggaag cagttcgcca ataaccacat cgatatacgt
     3241 aactaaaata aatcccagcg ccacagagat tgtactgcta atagccgaac taaaaggtag
     3301 tttaccgatc actggttcta gtaaagccgc gacagatcct tcaccgaccc acccgatgat
     3361 caaaccggtt agcgtaattc ctaattgact agctgataaa tagttatcta aatggtgtgt
     3421 aacatgaaga gctagcttgg cgttctttac attttccttt tctagttgtt ccaatcttga
     3481 tcgtctgatt ttcactaaag caaattcact tgctacaaaa aatgaagtaa ttgcaatcat
     3541 caaaaataaa ataatgaaat tgataaccat attctcccgc ctttctcttt ttctattgta
     3601 ccctttttct acaaaaagat tgaaaataat gcgtattcat atttaggaat aaaaaaggag
     3661 atgcggcatt tttcagccac atctccttat cacttcaaaa tcattgcgtt acttgttgct
     3721 aaacagcttt ttcatgacct ctgataaacg gtgttcaagt agctgacatt cgacattagt
     3781 tcaggtcaaa gcgctacttt cacaaccgct ctttcaacca tgttttccga gtatttccaa
     3841 tgataagcgg aacagtttca tgttttactt cgctgtactc tagcccaaac catgtttctg
     3901 gcgaggtagc gatttttttg attgccagtt ttgcctgcat gatttgacgt tgccattttc
     3961 ctagagttgt cacattggaa actacttcat caatcaggac aaattggaaa tcgccaactt
     4021 ctcgccctgg tgtcagagag tatctttgtg gctgttttgg caaacggcct tgtttcatca
     4081 aatcatggat gacttggcga acatatacgt tgatttcctg ttggaccctg aaacctaaga
     4141 acagattcac ttggacaata aaatcagtgt ccatcatatc tacttgatat tctttcgtat
     4201 atggctcatc cgtcacttcc acatgaacaa accaatagac tcgtgctctt ttaggccgtt
     4261 tatctaaaat cgaatagatg aactgtcggc caactttatc ttcagccata tcaggaacca
     4321 agaagaccac atttgtctga tagattggta aagaagtatc atcacgtaat tctctaagct
     4381 gcgggatata atctctcaaa gacacatcct cggttgacga ttcgcgaata atgttccctt
     4441 gttcccaaat aaacatcacg actaagatga tcaaaccaat cagaacggct acaaaaccgc
     4501 ctcggaagaa tttgacaaca cttgagataa agaaaacgac ttctatcgca ccgaagaaaa
     4561 aggtaactaa atatgcaagc caacgagaat gcccattttg gataagataa aagtaaagca
     4621 gtgctgttgt catcaacatc gtcacagtga tcgatagacc gtaagcagct tccatatgat
     4681 gagacgttcg gaatgtgaca accactagag aacaggcgat ccataaaatc agattgactg
     4741 ctgggatata catttgcccg atactgttcc caggatacat gatctttaac cgaggcagca
     4801 gtttcaactt gattgcttct gaaactagcg taaacgaacc tgtaatcaat gcttgcgaag
     4861 caatgactgc agcgactgtt gcaaaagcaa cgccgatcac gatccaactt tgaggcatca
     4921 tttggaagaa tggattcagg ttcttgattt gctgtgcttc agggttttga taaacattca
     4981 acaaccacgc agcctgccca aaataattga taaccaaaca aattttgacg taaggccagc
     5041 tcagacgaat atttcgtttg ccgacatgtc caagatcgga ataaagcgcc tctgcacctg
     5101 tcgtagccag gaaaatattt ccaagaatga acaagcctaa tttgttatct gcactaaaaa
     5161 gcagctggat agcataataa ggattcagtg cacggataac tgtccagtct tgactgaagt
     5221 tcattaatcc cattacgcct aaaaaagtaa accaagcgaa catgattggt ccgaatgctt
     5281 ttccgacaat atctgtacca aagcgttgga ccatgaataa aacaaaaata ataactaaag
     5341 tgataatgac gatcacgttc tggttattac cgaaccggtc aaaaaactgc ggaattcctc
     5401 gcaagccttc aatcgcagtc gttaccgtca cagcaggggt caatacccca tctgctagta
     5461 aggcagctcc tccgatcatt gcaggaatga tcaaatattt cccacctttt cggacaagtg
     5521 tgtagagtga gaaaattcca ccttcaccat ggttatctgc attcaatgca atcacgacat
     5581 atttgattgt tgtcagtaga gtcaatgtcc aaaaaatcaa tgagactgat ccgataacaa
     5641 aatcaggatt gattcctgac aatccgccat tatcttcaac aatcgatttc ataacgtaaa
     5701 gcggacttgt cccgatgtct ccgtagacga ctcccatcgc tacaagcagg ccagccattg
     5761 atatcttttt ggtattgtgc gttgttgcca cgtttttccc tcatttcttg ttatatggat
     5821 atcctttagg taagcttgaa tgatagatga tattcttatc catgacaccc gctttcctaa
     5881 attgcttcta attatccaag taacacactg aagtgtcaac ttatttgaat aaaattattc
     5941 tttctttgga cgttctctga tacgtcttgc cacaaatgaa taaagagcaa ggcaaaaaat
     6001 tgcacccaat aatgctggta tcaaataaaa accgccgagt tccggtccca gtggtcctag
     6061 taaaaattcg ccgagccaac tacctaaaaa accgataatg atatttccag atacgcctcc
     6121 cgggacttcc tttcctaaaa ttgcgccagc tatcaaacct aatataccgc cgataaataa
     6181 cgaccataaa aaattcagca tctcctttcc ctcctttatc catatttctc acttttattt
     6241 tacgctttat tcagaaggac tccaaaaata tgcgccaaga aactccagaa aaaaagaagt
     6301 tgtaacaaaa gtgttcagct tatttccgta gaagctgctt ctggaacacc gtgaatcaga
     6361 ggttgtgaaa tcagcggttt gacctgagta ttagagaaac aaacggaaaa atagttcctc
     6421 atattttgcc gttttttgag ctaatatcga gggacagctg attgaacatc gtttattgga
     6481 gaggttgtaa aaaagctgtt ctgcatcaag taataagaac agccaagtaa aaacagctcc
     6541 taatgttttt aacttggctg gacttattac cgcagatgca agcttttgaa caccgtttat
     6601 tcgaaaaaaa aggactgtga cacggctttt gtcacagtcc ccttttttcg aataattatt
     6661 gtccccctgt caccttcacg atcacaagta cattattcct atgaattaaa ttatttttct
     6721 tcatttttcg ttgaaccatc ttcgttcaac attgcttttc ttgacagatt tacgcgtcct
     6781 tgtttatcga tttcagttac tttcacaagg atctcatcac ctagtttaac aacatcttcg
     6841 actttattga cacgatcgtt tgctaattgg gaaatatgga caagtccatc ttttcctttg
     6901 atcaagttga cgaatgcacc gaatttttcg atacggacaa ctttccctag ataaacttca
     6961 ccaactttga cttctttggt caaatcttcg atgatcttga tagctttttt gatcatttct
     7021 gcatcagctg aagcaatact tacttttcca tcttgatcga tatcgatttt cacaccagtt
     7081 tcatcgatga ttccgttgat cgtatcgccg cctttaccga taacatcttt gattttagca
     7141 ggttcgatct ggatcatttc gatttttggt gcatattggc ttaattcttc acgtggagca
     7201 gcaatcgttg aagtcaattc ttctaagatt tccatacgtg cttgttttgc ttgagttaat
     7261 gcttcagtta ggatttgttc tgtgattcct tgaatcttga tatccatctg taaagcagtg
     7321 ataccatctt ttgtaccggc aactttaaag tccatatcgc caagatgatc ttccagccct
     7381 tggatatcag ttaggatcgt atagttttca ccatcagaaa caagtcccat cgcaataccg
     7441 gcgactggcg ctttgattgg tacacctgca tccatcaatg ctaatgtgcc agcacagata
     7501 cttgcttggg aagaagaacc atttgattcc aatacttctg ctactaaacg gatcgtataa
     7561 ggaaattctt cttctgaagg gattacttgt gctaacgcac gttcacctaa tgcgccatgt
     7621 ccgatttccc gacgccctgg agagcctgca cgtcctgtag aaccaacaga aaattgaggg
     7681 aaattgtagt ggtggatgaa tcgtttgctg acttccaccc ctaaaccatc aatgatttgg
     7741 tgctctccta gaggtgcgag tgtacaagct gataaagctt gtgtttgtcc tcgtgtgaac
     7801 aaacctgatc catgtacacg tggcaataag ctgacctctg atgacaatgg acggatttca
     7861 tccaatttac gcccgtcagg acggatctta tcgatggtga tcaattcacg tacgacatct
     7921 ttttcaagat cttctgtgat ttgtttaact tctttcaaca agtgatcttc atcttcatga
     7981 cctgcaaatt tctcagcata agcttcgcgg atatcgatct tcacctgctc gatattatct
     8041 tcgcgagcaa gtttttcttc agtcattact gctgctttca ttgtagcgta agaagcatca
     8101 aagatttctt ttttcaatac ttcatcaact tgcagtaaag tcacttccat tttttctttc
     8161 cctactgctt gaacgatttc ttcttggaaa gcaactaact ctttgatagc gtcaaaacca
     8221 aacagcaatg caccaagcat gtcttcttct gaaacttctt tcgcgccgct ttcaaccata
     8281 ttgatggctt gtttcgttcc ggcaacagtc aattcgatat ctgtttgttc tgcttgttct
     8341 actgttggat tcaagacgta ctcgccattt acacgaccaa cttctacgcc tgcgattggg
     8401 ccgtcaaatg ggatatctga gattgatagt gctaaagaag aacctagcat tgctgccata
     8461 gctggcgagc agtctgtttc tacactcatc acgatgttcg ttacttggac ttcattacgg
     8521 aagccttctg caaacatcgg gcgaattgga cggtcgatca aacgggcagt caatgttgct
     8581 tccgtacttg gacggccttc tcgtttgatg aaacctccag ggattttccc tgctgcatac
     8641 attttttctt cataattgat cgttaatggg aaaaagtctg tatcttttgc ttctttagag
     8701 gccacagctg cacttaagac tactgtatct ccataacgga ctaaaacggc tccgtttgct
     8761 tgttttgcta gctgaccgac ttcgatttgt aagggacggc cgccccatgt cgttttgaat
     8821 acttgttttt ctgacataac ttctcctttt ccttctcgtg aaagcaagac gctactaaac
     8881 aaatgaaaac tgccgaaagc cgtcttttga gcagctttca tttggttagt aggagtccat
     8941 ctagcttgat cacggaattt tacttaattg atatacgagt aaaaaaagtg agattcatgt
     9001 gaatcccact ctttttgact aaaattaacg acgcaagcct aaacgtttga tcaattcgcg
     9061 gtaacgttga acgtcagttt tacgtaagta agctaacaag ttacggcggt gaccaacttt
     9121 tttcattagg ccgcggtatg aatgatggtc ttttttgtgc acgcgtgcat gttcattcaa
     9181 gtggttgatt tcttcagtta atacagcgat ttgtacttct ggagaaccag tatccccttc
     9241 atggcgagcg tattcgttga tgatttcatt cttgcgttct tttgaaattg ccatttcttt
     9301 cacctctttc gattattccc ctgcgactga gtaaaacgtt ggtgattcgc ttaaccaagt
     9361 ggcaggtcat gtgcctagag cacacagcta tactttacct gaaaccgggt tgaaaatcaa
     9421 gtagttaatc attaagaaaa ggtagttttc aaacaatctt actactactt ttccattttt
     9481 gtggtaaact ataatgcgaa aatagacttg aaacacagtc ttttaagaaa ggggtacata
     9541 ttccatgatt acaatggatg atatcattcg tgaaggaaat ccgaccttac gcgaagttgc
     9601 aaaagaagtt tctcttccat taagcgaaga agatatctct ttaggaaaag agatgcttga
     9661 gttcttaaaa aacagccaag atccaatcaa agctgaagaa ctacacttac gaggcggtgt
     9721 tggcttagct gctcctcaat tagatatttc taaaagaatc attgctgttc acgtaccaag
     9781 tcctgaccca gaggcagatg gaccttctct aagtactgtt atgtataatc ctaaaatttt
     9841 gagccattct gttcaagatg cttgtttagg ggaaggtgaa ggctgtttat ctgttgatcg
     9901 agaagtacca ggatatgttg ttcgccatgc caaaatcact gtgtcttatt atgatatgaa
     9961 tggtgaaaaa cacaagattc gtttgaagaa ttatgaatcg atcgtcgttc aacatgaaat
    10021 cgaccatatc aacggtgtga tgttctatga ccacatcaac gatcaaaatc catttgcact
    10081 aaaagaaggc gtattggtga tcgagtagag aattggcagg ttccttcgat actatgctac
    10141 aagaaagctt tataaaaaag gggagtgctc aaaagctgca cttccctttt ttatgtttct
    10201 ccactaatcg aaatttagat agacatctag aaatcgcaat tccaaaaaat tctgtgtatt
    10261 ggatacgcat cttttcttat tttttcttat ttcttccata tgggtgttta tctcagagat
    10321 gatagaatag tttctaggat aaaaagtagc agctacgatg ttatccttcg tagaggattc
    10381 ctgcttcagc tagtttttgt ttgatgtttt tcagcatatg cttttctggg tagcggatcg
    10441 tatgcagatg gatgccgcct gttaattcgg ataacaaagt agcattactt ttttgataac
    10501 gtctcataaa ggaatcgata tcttgtggcg ttttgatgtg caaagttcct gctaactcac
    10561 cgtaaagggg atgttccaca attacatcaa tgatttcacc accattttca acgattagtc
    10621 tcagttcttc ttctgtttga tcttttccat gctggacagc gattttactg atgtgcccag
    10681 tattggtttc ttctgtttcg aggatataac ctcttgctgt tgccacgata cttttacctg
    10741 cagctcgtag taaagcaata tcgcctacaa tgatctgacg gctgactcca aaagttttcg
    10801 caaacttgct agcactcact ggtttttctg tatttgccaa ggtttgcatg atttgttttc
    10861 gccgtgtctc tccttcgatc acacttattc ctccttcatt ttgttttggt attcgcgcga
    10921 gtgtttcatc aaatcaacat acgtgtctgt tattgtttcc ttatatccct tatttttcag
    10981 cagactaaca actttatcca atacttgctg ctctcttttt gcatcataaa ctgcttggtt
    11041 ttcttctttt ttcacttgtc ctattttagt taccgtatcc attctttttt ctaataaagc
    11101 aaccaactct cgatcgatca tatcgatctt atgacgtaat gtttcaagag actcttctgt
    11161 tagttcttcc tctactgtct tgatgatacg agcaggattt cctgcaatca ctacattgtc
    11221 gggaaaagat ttggtcacaa ccgaacctgc gccgactact acgttgtccc ctagagtgac
    11281 acccggcgtg acgataactc ctccgcctaa ccaaacatta ttaccgattt taatgggttt
    11341 tgcgtactcc agaccgctgt tacgtttcac tggatgtagt ggatgcgtcg ccgtgtaaag
    11401 ctggacattc ggagcgaaca tgcagttatc accgatttca atcgtgctga catctaaaaa
    11461 tgtacaattg aaatttgcat aaaaattctc cccaacaaat atattatatc cgtaatcaaa
    11521 attgataact ggctccatat agattttttt ccctgtacgg ccaaaagtct ctttcaacaa
    11581 ttgggatcgc agttccgctg attctgcttg gttgatgatt tggctttgac ttcttgcaaa
    11641 catacggtcg gcaaccagct caggatcatt ggcaaaataa agctcgcctg caatcatttt
    11701 ttctttttcg gttttgaatt cagtcataat ctgctcctaa ttcttgtatt tttttgaaaa
    11761 caaccgctcc gtcttcttga ataaacgtat aaggctccgc taaataaaca ggcgtttgat
    11821 tgattactaa gattttggct gacggctggc gaaactgtac cagatcacaa aacggatgaa
    11881 cttgaaaact cgttccaaca atgacgatca gctctgcttg gctgacggca taagccgcct
    11941 gctccatgac tccatcttga aacccttcac catataacac gatgtctggg cgtatttgtc
    12001 ctccgcatgc ttgatgtttg tcgctgtgaa gatattcttt ccagtctacc gtttgttgac
    12061 attttcgaca atgacattga tacagactcc catgaaaatt gacgagttgc gggcttttag
    12121 cctttgcgtg caaaccgtcg atgttttggg aaacaaccca aacatttttt tctttcgcta
    12181 gatgtgctat ttccaaatga atgatattgg gttttgcttc aggatgataa atctttttga
    12241 caaattgata gaatttatcc ggttcattca ccattgcttg atgactcagc aagtattccg
    12301 gctgctccat cccgtggtag attcctgaca aagatcgata gtctggcact ccagaaggtg
    12361 tggatacccc tgcaccggtc aaaaatgtaa tttgctgata agctaatatc tcttttgctg
    12421 cttcgtctac tgttaattgt ttcatgtttt gtcacctcac tttccattat agcccatact
    12481 cgaacaaatt tattgttgaa aagtcagaaa aatgggaata aaaaagtgtt atgggcattt
    12541 gagcaattta tcacaatgtt cactgacaaa agaatgaaaa cgtgttacaa tactgctgta
    12601 taaaagtgag gtgaatcgat atgttaccat tctttattta ttggggcgtt attctggctt
    12661 gtatcgcctg gttagcgtta agcgtttatt tctctgtttt ttatcttgta cgcaaagaaa
    12721 atggaaatct ttgggctttt gctttattca acgtgattgc cgcaattgtt ttagccatta
    12781 cattagccgt atatcgaaca tggggctggg gaatcaccca atactcaagt ttgatttatc
    12841 taatattagc catttatggc gtcgttgttc ttttgcaagc gatcctagga cgtgagccaa
    12901 agaaagcggc agcttaaatg atcgagatgg aactggacac aggaaatttt ctgttctagt
    12961 tcttttttta ttgtattaca tacatttttg tgtataatta tactatcgtt tgcaatggat
    13021 agatgattca cattttgatt gttttttcgg taaaagtaaa gatttctata tttatcagta
    13081 ttttttcaaa aaccagcagt tatagattga caaagcctct cgagtatcgt aaactttttt
    13141 tgtataaata actgaatacg agatgcctca atcaatgagg tagaggtcgc gagaatcatt
    13201 aaccctgtgg agtgaagcaa acatggagaa gcaggaatag ggaggatcgc cgaaatgtgc
    13261 acttttttgc ttggagtgta tgttgggacg caagttaaga gcttgcggac tgtcttagca
    13321 gtgatgctaa gttgcgctat gttttgtgag aggtttatca ccttatggaa ttttagcggc
    13381 ctttttatat ctataaatcg gtcgcttttt attttttcag ataaagcttt accgcatttc
    13441 atctagaccg ctcgtgtatc atataatcag aaagggagaa aaaaatgaaa aaaaatatgg
    13501 tttcagttgc cgtactattt gcttttgtct tctcactatt cagtgtggga tctctggcaa
    13561 atgcagatga aaaaacaccg agcgatgagt ttcgcgtagg tatggaggct gggtatgcac
    13621 ccttcaactg gtctcaacaa acagatgaga ataatgcctt gccaattcaa ggccaaaata
    13681 gttacgccgg cggttatgat gttcaaatcg ctaaaaaagt agcagatggt ttagggaaaa
    13741 aattagtcat cgtccaaacg aaatgggatg gtctggctcc tgcccttcaa tcaggcaaga
    13801 tcgacgcgat catcgccgga atgagcccta ctgctgaacg acgaaaagaa attgatttta
    13861 ccgatcctta ttacgaatca caattagtag tagtagttca aaaagatagc aaatatgcaa
    13921 aagcaaaaag tttagcagat ctttctggag caaagatcac tgctcagtta aatacattcc
    13981 actatactgt gatcgatcag ataccagatg tgcagaaaca acaagcaatg gataatttct
    14041 cagcaatgag aacagcttta gcttctggaa tgatcgatgg ttatgtcagc gaacgtccgg
    14101 aaggtgtaac ggcaactagt gtgaacaaag acttggaaat gcttgaattc agcggtgcag
    14161 atggcttcca gacaaacccg gaagatgttc agatttctgt tggtatgcgt aaaggcgacc
    14221 cggatatcca aaaagtaaac cagattcttt ctggcatctc taacgatgaa cgaaccaaaa
    14281 ttatggacca agcagtcaaa gatcagcctg ctgcaactga tagtgaagaa aaacctggca
    14341 tcatttctga tttcactacg atttggaaac aatacggcaa tatgttctta cgaggtgctg
    14401 gacttacctt gttcatcgca ttgatcggga cagttgtcgg tactacactt ggattactga
    14461 ttggtgtctt ccgttcggta cctgaatcag gaaatgcact gactcgcttc ttccaaaaaa
    14521 tcggaaatgc acttctttct atctatgtcg aagtattccg cggaacaccg atgatggtac
    14581 aagcaatggt catcttctac ggtctggcac tcgcttttgg catttcattg aaccgaacga
    14641 ttgccgcttt gtttattgtc tctctcaata ctggagctta catgacagag atcgttcgtg
    14701 gggggatttt tgcagtagat gaagggcagt tcgaagctgc gcaagccatt ggtatgaccc
    14761 atggccaaac gatgagaaaa gttgttattc cacaagtttt acggaatatc ttgccagcaa
    14821 caggaaatga gtttgttatc aatatcaaag atacagcagt tttaagtgta atcggcgtag
    14881 ctgatttgtt cttccaagga aactctgctt ccggtgcgaa tttccaattc ttccaaacat
    14941 ttacgatcgt cgggatcatc tacttagtca tgacctttac gatcaccaga atcctgcggg
    15001 cggtagaaaa gaaaatcgat ggtccttcag cttataccaa gcttgaagaa atcgacaatt
    15061 caaatttgca ggaataagga ggaagaatca tgaatgaaaa aattattgaa atcaaacatc
    15121 taagaaaaag cttcggtgaa aatgaagtat tgaaagatat cagcgtaaca gtcaataaag
    15181 gtgaagttgt gacgatcatc ggttcttccg gttctggtaa atctactttc ttgcgctgta
    15241 tcaatttact ggaaaaacca acaggcggcg agatcattta taatggagaa aatgtattag
    15301 ctcctaaata taatttacct aaatatcgaa cgaatctagg tatggttttc caatccttca
    15361 acctgttcaa caatatgaat gtcttggaaa actgtatgtc tggtcaaaca actgtcctga
    15421 aacgagataa agaaactgcc aaaaaagtag caatcgaaaa tctggaaaaa gttggtatgg
    15481 atcgttatat cgaagccaaa ccagcacaat tatctggtgg acagaaacag cgtgtcgcaa
    15541 ttgctcgggc attatcaatg aatccagatg tattgctatt cgacgaacct acttcggcgt
    15601 tagaccctga aatggttggc gaagtgctta atacgatcaa agacttagca catactggct
    15661 tgacaatgct tatcgtgacg catgagatgg aatttgcaaa agatgtatct gaccgtgtca
    15721 tttttatgga taaaggtgtg attgcagaag aaggtacacc agaagatatc tttgtccatc
    15781 cgaaagaaga acgtacaaaa gaattccttt cacgtatttt aaatgcttag gatcaatagc
    15841 tgattgggac aaagagctgc ggtgtttacc gcagttcttt tttatgaatt actcataaaa
    15901 ggtaaatttc tgaa
//
LOCUS       DADQDV010000064        15466 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.066, whole genome shotgun sequence.
ACCESSION   DADQDV010000064 DADQDV010000000
VERSION     DADQDV010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15466
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.066"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..2569)
                     /locus_tag="J8S10_002241"
     CDS             complement(<1..2569)
                     /locus_tag="J8S10_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630821.1"
                     /translation="MNQYVKKLIASILFVFPLLMVTSVFADVEKTSESTQSENQSFDK
                     TTFSEESITSETTESQSEAPTSNTRQEENKTSETSEVAEQTSDSSEEVQVRVVSADGY
                     SEAATTEELTQLLADESVAKIRLTQPLTLDRELEIKRDIVIDFGGLAHNFGTHHIYIN
                     ETPQSIEFQNFKGTAAHPGGLIPNIDGNAIIIAYMSDFWGNRYHFTGEIKFTGTLDLY
                     DGSKLGLIYAPRATVTLDGVSGVLDVQPVKEGMNAAPGKAYFCRSYQLNVINGSQLYG
                     PYLGKFYGFLDSGDETGSGKTAPGLHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVT
                     FKVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSRVAVSNDGKITINTATTGGFRLQG
                     DSSQIHVSSGGQISVKMAGDGDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSA
                     VRFENGTQKLTVTNGGSLKVRNAGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFT
                     VTGEKSNIDIRADSGATVDTTGDIDLNFMAGEKTYLVMVGKTGEDKTGIISGDVLNVD
                     LESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKAGVTFDNFEKDP
                     DYFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRV
                     PTNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSPVEITALTQGQTDE
                     NEGTGYNPWGEGEQGGLFEVQVPNEERLTTGDQVQIVAAKKVRGGQEVTELDSAKTTV
                     DVIPPEPAKLSTTLINAASRSITGTGEAGALVSLKKNQAVLSETTIDDTGKFVLSIPE
                     "
     gene            complement(2791..3675)
                     /locus_tag="J8S10_002242"
     CDS             complement(2791..3675)
                     /locus_tag="J8S10_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HAZ9630822.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPEAINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSILLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            complement(3770..4207)
                     /locus_tag="J8S10_002243"
     CDS             complement(3770..4207)
                     /locus_tag="J8S10_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630823.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWVFYLVKK"
     gene            complement(4424..5335)
                     /locus_tag="J8S10_002244"
     CDS             complement(4424..5335)
                     /locus_tag="J8S10_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAZ9630824.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            complement(5712..6350)
                     /locus_tag="J8S10_002245"
     CDS             complement(5712..6350)
                     /locus_tag="J8S10_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9630825.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDFVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFNQETKHLTGREKRLIKRNALSFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKEQVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            complement(6354..7124)
                     /locus_tag="J8S10_002246"
     CDS             complement(6354..7124)
                     /locus_tag="J8S10_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HAZ9630826.1"
                     /translation="MIDVSGRLIQITEKETHPVILIPERYRHTDLKNDLAQITEYYQE
                     ISEKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSTYWERNILSGEIYPPLK
                     IKIGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLSRSFHYLIQIFLLTFFS
                     FFLLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNLIKWGTTSVIFLFLIER
                     EPKYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            complement(7542..7958)
                     /locus_tag="J8S10_002247"
     CDS             complement(7542..7958)
                     /locus_tag="J8S10_002247"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630827.1"
                     /translation="MMTREKEAYERFILLFVERFNQAFHTDYATNIFEDFENSYSYSV
                     ISSTDVYNYRVYLTIGLILLFLLLSSFFLLMNKEISLLLNNGFSLHQVLWCLLGKKKI
                     IITFIIAGIIGGFIFMYYKEQFLYLFQMYVFLFSGI"
     gene            complement(8009..8390)
                     /locus_tag="J8S10_002248"
                     /pseudo
     CDS             complement(8009..8390)
                     /locus_tag="J8S10_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339091.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            8516..9181
                     /locus_tag="J8S10_002249"
     CDS             8516..9181
                     /locus_tag="J8S10_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAZ9630828.1"
                     /translation="MNIGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHQTLGLPIDFPSIESATESIEPTLPDEPLVIKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETVDRFNPFLKPQIGYTTLPVGYVENSIEHWVCNDIFVHGTW
                     LSFHAGEVEKGKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILIQDYDDALKRSPQEP
                     DRH"
     gene            complement(9578..11611)
                     /gene="brxL"
                     /locus_tag="J8S10_002250"
     CDS             complement(9578..11611)
                     /gene="brxL"
                     /locus_tag="J8S10_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002397592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease Lon-related BREX system protein BrxL"
                     /protein_id="HAZ9630829.1"
                     /translation="MEQQEILKLSEFFPGKIVRKDLTKKIKEGANVPVYVLEYLLGMY
                     ASSLDETLVEKGVENVKNILARNYVRPDEAEKVKAKIRELGGYTVIDKVTVHLNEKKD
                     CYEAEFSNLGLKNVQISEEYPKKFDRLLGGGIWCIVSMEYWYDENDRWNSPFIAKKVD
                     PIQMPGLDIEAYKMARKEFTTNEWIDLLLRSIGMEPTQFNKRVKWLHLARLIPLIENN
                     FNLCELGPRGTGKSHVYKEISPNSILVSGGQTTVANLFYNMASRTMGLVGMWDCVAFD
                     EVAGIKFKDNDGVQIMKDYMASGSFARGKEEKNASASMAFVGNINQSVDVILKTSNLF
                     EPFPEVMGTDSAFLDRMHCYLPGWEIPKYRPDFFTNDYGFITDYFSEVMRELRKVSFG
                     DSFDKYFKLGSQLNQRDTIAVRRIVSGMMKLLYPDGRFEKSDVEEILRFALEMRRRVK
                     EQLKKIGGMEFYDVNFSYIDLEEEREEYVSVPEQGGGTLIPEGLGKPGHLYTVSYGKT
                     GQLGTYKLETQMTSGNGKFERTGINSDAGAREAMDSAYRYLRANYGSVSQSISLTTKD
                     FVVHVQDMNGIGMTKTLSLSTIIALCSVSLNKPVLPSLVILGDITIGGSMIKVDNLAN
                     CLQVAKDAGAKKVLVPMISAADIGTVPPELMGTFNLIFYQTPEDAVFKALGVE"
     gene            complement(11729..14251)
                     /gene="pglZ"
                     /locus_tag="J8S10_002251"
     CDS             complement(11729..14251)
                     /gene="pglZ"
                     /locus_tag="J8S10_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BREX-1 system phosphatase PglZ type A"
                     /protein_id="HAZ9630830.1"
                     /translation="MTDINTQQIEEKLNQRFPNYGCRKIIFWFDSNQDFLEEIDSLVI
                     QNAKIYRLEKDAQFKTKRLLEYEDPETNYLIYAPFPRWDDKDEDNHLLSVLNYSEEFS
                     ADRLAIIMNELAIPLRFHQTVKQYRNFFNAKDRMRSFGEFSTHMTINKSETIELMIMA
                     VLLKSKSIRLNDLLRVVLKSFTESRENPLRELDKYQLTAKFWEFIQMKFGFTDSQPTL
                     EKLTMCLYLNYFYYQIDQEMPKKFKGFEILHLKANIITFMDQFMNDTRYMESFEQLSK
                     KVYQAIDGDGLLDSIEIDDLIEADVFSEIHAKILMFYAERLKASDTTTKIAGQTIFDS
                     LKQREKMHFASDYIYEYQLLKHAYYLVDKNRLCLPMNMDNLLTQYEKEMYWVDTHYRK
                     FIWNSDHIEEKQKYGQLYRLVEANYSKFLDQSGQIWNQTFEFKNRPSIRKFYNQAVMK
                     RSVKTVVIISDAFRYELGMNLERKLVREKKYSTNMASFLSVLPSVTEFGKAALLPNNQ
                     LTYNEGTEVLIDGKKTNGLSNRNAILQQRDANAVALNYDDVVKMNKAEVREVFNGKSV
                     IYIYHDQVDRTGDHSNENRVFEACDLAISEISRLINRLHNDGSIYRFIVTADHGFIYK
                     RSHVEEVDKIENPSRNEKDRVERRFILSEEEYEIIGTKNYSLGDSLGNDDTRNICVPI
                     TSSIFKKAGGGQSYVHGGSSIQEMLVPVLEITVAKGSNAKEPVAIELMTSNRRITGLS
                     TTLEFYQKNAISDVYDPASFWLYFEDEYGERISNEEIYVADSKTEDANQRFTKFVFEF
                     VNRRYTVEDTYYLVIKNQKNDLTERIKFIIDNPFAESFDFDI"
     gene            complement(14367..15311)
                     /locus_tag="J8S10_002252"
     CDS             complement(14367..15311)
                     /locus_tag="J8S10_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002397590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630831.1"
                     /translation="MFKKDLSEAFNCLSRQLVNQFNTLKSNEEELNDIFINHYSLEKE
                     LTKEVQDEYISARLPDKAREIKDFISYSIGCIFGRYSLDEDGLIFAGGEWDPSRYQKF
                     KPDTDNVLLITDDEYFKDSQIDIVNRFIDFVEITFGKETLEENLQFIADTLGGKGTSR
                     EIIRRYFVQDFYKDHLKTYSNRPIYWQLDSGKQNGFKALMYLHRYTPDQLGKVRTEYL
                     HELQKAYDNRIELRQQQISTSDNPKERNAMTKEIVKIQKQLKEVREYDEKLGHLALKR
                     IELDLDDGVIVNYDKLQRDPKTGEKFQIFAKGVKEPKK"
BASE COUNT         4744 a         3107 c         2339 g         5276 t
ORIGIN      
        1 tttctgggat agaaagaaca aatttacctg tatcatcaat agttgtttcg gacaaaacag
       61 cttgattttt tttcaatgaa accaaagctc ctgcttcgcc tgtacctgtg attgagcgag
      121 aagctgcatt gatcaatgtg gtacttaatt tagcaggctc aggaggaatc acatcgactg
      181 tcgttttggc agagtccagt tctgtcactt cttggccgcc tcttactttt ttagcagcaa
      241 ctatttgcac ttgatccccc gttgttagtc tttcttcgtt gggtacttga acctcaaaca
      301 aaccgccttg ttcgccttct ccccacggat tatatcctgt cccttcattt tcatctgttt
      361 gtccttgtgt gagagcagta atttctacag gtgatttcgt cgtatctgca taagtaatac
      421 gtaaagtcac ttctacttcg cctgtccaag catctcttgg ctttgcctcg acaccttcgg
      481 gaacaacgac atgcccatag atttttttat ctgcattcgt tggtactctt aaggattcaa
      541 tcatcggaag ctggttattg gcactgattc gattataatt tttcattccg gcacctgtct
      601 gagcaaattc atttgttaaa cctgcactag ggcttgatac aaaattacct aagtcggttc
      661 cattgatcga taagtctgtc atatcagaaa aataatccgg atctttttca aagttatcga
      721 acgttactcc tgcctttcgc cataaagcaa tttctgaatg agcgatcttc aaagaagaat
      781 cgccatttcc ttgaaatacc cagccaccta tgccattagt ctcgcttccg atccgtttgt
      841 tttggaaatc gaaataggta ggagattcta agtctacatt caacacatcc ccactgatga
      901 tgccagtctt atcttcccca gttttcccga ccatgactaa ataagttttt tcgccagcca
      961 taaagttcaa atcaatatct ccagttgtat ctacggtagc tccggaatct gcgcgtatat
     1021 cgatatttga tttttctcca gtaaccgtaa aatcagctga ccctggactt tctagaaaac
     1081 cagaagcgtc ataaaattgg atcgcttggt ttccttgatt gagtctgttc acataagatt
     1141 tgccatcccc tgcatttctt accttcaatg agcctccatt agttactgtt agtttttgcg
     1201 taccgttctc aaaacgaact gcgctagaac gaccactttg cttatcaata tcgatgactg
     1261 atccggctcc ttctacgatc aaagaaagtc ctttccctac aaaacgcatc ccattgtttc
     1321 caggttggtc gccatctcca gccattttga ccgagatttg tccaccactt gatacatgga
     1381 tttgactaga atctccttgc aggcgaaatc cgccagtagt cgctgtattg attgtgattt
     1441 tcccatcatt cgacacagcg actcttgatc ctgagcctct catttggata attccgcgat
     1501 tgttgtcgtt ggtaatattg atctttgtat ttaccgaaaa ttcacttcct gagccactga
     1561 ctttaaatgt gacattcccg ggtagcgtat cgacagcctc tccttcatcg ctgacgccat
     1621 ctgcccgatc atagtcaaga gagacctttg aaccactcaa gatatggagt cctggtgctg
     1681 tttttccact gcccgtctca tcacctgaat ctagaaaacc atagaatttt cctagatatg
     1741 gtccataaag ctgactacca ttgattacat ttagctgata gcttctacaa aaataagctt
     1801 tacccggagc ggcattcatc ccttctttca ctggttggac atccaataca ccggaaacac
     1861 catctaatgt gacagttgca cgaggggcgt aaatcaggcc taatttagaa ccatcatata
     1921 agtcaagtgt cccggtaaat tttatttctc ccgtaaaatg atatctgttt ccccaaaaat
     1981 cggacatata agcaatgata atggcatttc catcgatatt tggtatcaac ccacctggat
     2041 gagctgccgt tcctttaaaa ttctgaaact cgatcgactg aggtgtctca ttgatataga
     2101 tgtgatgtgt gccgaaatta tgagcaagtc cgccaaaatc gataacgata tctcgcttga
     2161 tctccaattc cctgtctaaa gtcaaaggct gagttaaacg aatcttagct actgattcgt
     2221 ctgcgagaag ctgcgtcagt tcttctgttg tggcagcttc gctgtaccca tccgctgaaa
     2281 caactctaac ctgtacctct tcactgctat cagacgtttg ttcagctact tctgaggtct
     2341 cacttgtctt attttcttct tgccttgtat tagaagtagg cgcctcactt tgggattctg
     2401 tagtttcaga agtaattgat tcttctgaaa aagtagtctt gtcaaaactt tgattctctg
     2461 attgcgttga ttcgcttgtt ttctctacat cggcaaaaac ggatgtcacc atcaagagag
     2521 ggaagacaaa caaaatcgac gcaatcagct tttttacata ttgattcatt ctccaccatc
     2581 ctctctgacg ttttgacaat tttattttaa cgttttaatt tatttgtaat tgtactttca
     2641 tatttaaaat atgtattttt atggcaaatt tttctgttag gtgaaaattt cttttttgta
     2701 caaaaaaagg ctgtgacaaa agtcttgtca cagtccctta ttccgaacaa ccgatgtcct
     2761 cctgacaact cttcggtcac aacctccatt ttaacaataa acctgtaaat gtgagggtaa
     2821 cactttgatt gtcacaggta atttatcccc ttcatctcca tcaacattcg tcgtcaattc
     2881 ttcctcatca gctaatgaca caactaattg ctcacaagta agataggcta gatttttcgt
     2941 agattcatct actcctttta ataggtctgg caatgtttta agcgtatcga tcaaagaaga
     3001 atcttttaaa taaaccaaat ggagcttacc atcatccact tttgcatttg gaagtaatgt
     3061 ttcaaaaccg cctactgagt tagttagtcc tatcagcaag atactgctct caatttcttc
     3121 cttctttcca tcaacttcta cgtgaaacga gtaggattgt gtggaagcta actgtttgat
     3181 tcctgacatg aaataagcta gttttccaaa tttcgtcttc ttctccgcat ctacatcatt
     3241 gattgcttca gggatagagc caattgcgac gacattcata aaatagtcgt catttatttt
     3301 tccaatatcc aatggcttga ctgattcaat cgaaaaatga ttgatcgctt cctcaggttc
     3361 tagcggtatc cctaatgctc gagccaagtc attcaccgta cccaatggga aaaatccgaa
     3421 atttggccga tgttcttgtt cagcgattcc actgattcct tcgttgactg ttccatctcc
     3481 gcccatgaca aacacactat gatacccttc cgtagccgct tcgcgagtaa agttttttgc
     3541 atcccctgct ttttttgtat gcaagacgac cacttcatca aacaccgatt ccaattttgc
     3601 tatcgctaat tgctcaaatt cctttgcttg ttcaccgcct gaactggggt ttaccactaa
     3661 taaaactttt ttcatcactt tctttccctt ctgattgatt tctttaatat aacgatagca
     3721 taaagaaaaa aattaggctg tgatgaagta ctgttcatga aacattcatt tattttttga
     3781 caagataaaa tacccatact atgaaactga ggaaaattaa aacaatgata taggaaataa
     3841 aagaaaatga taggcattgt atacctaata aagtaaaaat cttaggtggc agataaaaac
     3901 acaaaaatag caagagaatg taatagcgtt tcttccactt tttgttatca gaccttatag
     3961 cgatcagagg aataccaaat gcataactga aaaactcttg atgtactgtt aatatgtcac
     4021 gaccttgaat aataaatgca acaatccccg ctataattag tgtgcctaat accaaaacgg
     4081 aaaattgatg aatatatttt atatacaaat gatccattgt acttcctgcc tttttatttg
     4141 tgagaaaaac aaatccgtat acgtgaataa cttctagaaa taaaagaaat ttgcaaaacc
     4201 actccattta tctacttcta cgtgcatttt ttaatatcgt tttctttatt taagattata
     4261 cagaaaaata tctagggtgg ctggattcta agtaaaaaaa atttttaaaa taaaaagaac
     4321 taaatcaagt aataattaaa ctactgttga tttagttcta ataaaaagat ttagatgaac
     4381 agttttattg atttaaatag ttcatatttt ttatttatac cgcttattta ctacttgctg
     4441 tactagaatc tgaagtgaat gtactcaaaa cattttcaaa gtctttgtct ttgattttta
     4501 cattagcgtc tttcaatact tcgccaatta ctttattctg gaaggtactg tcacttaatt
     4561 ttgtgtctgt tgcaatttct ttcaattctt ttttgtattt atccatgtcg ttgcctttgt
     4621 tttggttttt caccatttta accacataat attccgtagt ataagttgaa gcattggtag
     4681 aagtgatcac atcagaaact tgaccatctt tcaacttaaa ggctgcttct ttgacttctg
     4741 ccggaaccgt tgtagtagtg gaatcaaatt tcacttttcc gccatcttct tttgtcgtag
     4801 tatcagttga cttgtctttg gctaatttag agaaatcgtc tcccttatca gcagctttct
     4861 tcacatcttt tgcatcatct tcacttgcta cttggataat ttgagcttcc acttctggat
     4921 ggaaagattc ccaagccgtt tttaaatctt catcggtcaa tttgatatgt ttctttagac
     4981 cttcttgaaa ggctagactt tgtttgatac tgtctttgaa tgtttgttct gtgtaacctg
     5041 cagatttcaa ttgtgaatca aatgaatcac ccaattgttt ctttgtttga tcatattggg
     5101 aatcgatttc tttggttgat acgtcatctc catatttatc ttcaaatact tgataaacga
     5161 tcaactgttg cacagcggaa tctgctcctt gcattttttt caagctatcc attacttctt
     5221 gttcgctgat tgtaccgcct ttataactaa cggctgtttt ttcaccggca ttcgtacagc
     5281 ctgacaataa gccagtgcct agtacgatgg caagtgctaa aaatcttttt ttcatttatc
     5341 aattctccta cttttcgttt tttgcgaatt gctaaaaaca aaggtgttca agatgaaaat
     5401 catcaagaac acctttacta atctgctcga tacgtcctga atagatataa ggctacacaa
     5461 tccagaaagt tcgctcagca gaataaatgt caagtagcac atcacacctt aatatactac
     5521 ttcttttgtt accgtttttc aagtctatct tgcgttccgt atttaacgta actaattctt
     5581 agaacaaatg ttatcgattt tgtttttctt cttccgctgt tgggatattc aaatcagaca
     5641 cttttatgtt cgattttcca gacatttttt tgttgttttt attagaaaaa gtttgttttt
     5701 tcatttgttt tctaaagcat gatcttcttg tttcctattt tggtcagata tggatcatgc
     5761 gtgaccacga taactaacgt accttgggaa gcctgttgcg ataagatttc aacgacttgc
     5821 tccttatttc gtttatctaa tgatccagtt ggttcatcgg ctaaaatgat tttgctattc
     5881 ttcaataaga ctctcgcaca ggcgattctt tgcttctcac caccagataa tgtgtagata
     5941 ggcgtactta gcttcttgtt tatatttact tttttcaatg cctcatactt tgctgttcgc
     6001 ttatctgaaa catttaaatt cgaaaacttc aatccaatat ctaaattaaa atcgattgtt
     6061 tcatattcaa tcaacccaaa atcttgaaaa agaaaagaga gggcatttct ttttatcaag
     6121 cgcttctctc ttccagttaa atgttttgtt tcttgattaa ataaataaaa ttgccctgaa
     6181 ctgaattgat cattcaatcc taatatattc aataaagtac ttttccctgc tccgctctct
     6241 ccaactacag tcacaaaatc cccagcatcc gcagtgaaac gatccaaatg aagaatcgtt
     6301 ttgtttcgaa tgattttttt cgcacctttt atcactatca acggctccaa ttgttaacct
     6361 ccattcatca gcaataactg acttttcttt tctgtagaca aaataaaaac aactgaaaga
     6421 ataaaatcaa tgaagctaaa gaaaaaaata ttaaaaagat atttaggctc tctttctata
     6481 agaaaaagga agattacact tgtcgttccc catttgatga ggttcatcat gaagaaatct
     6541 ttatacgttt caaagagcga ataaccactt gaacgaaaga tagcgatttt ccgacaattg
     6601 tagacaaaat atatgcataa catgacatag ctcaacaaga agaaagaaaa gaaagtgagt
     6661 aaaaatatct gtatcaagta atgaaatgat ctgcttaaca ctttgacagc tatctcttca
     6721 gtctgagtat acggaaatga taactgcaag ttatcacgta actgactttc ttcaatcagc
     6781 tcaaataacc tttctttcga caaagagcct atcttgatct ttaacggtgg atagatttct
     6841 ccgctgagaa tatttctttc ccaatacgta ctgtttttca atgtcagtat ttcaacaacc
     6901 ggataatgtt cgatccaggg gatagaagga ataaatgtat aaatgggttg attgtttttt
     6961 ataaatagaa atttcggttc tttttcactg atttcttgat aatattctgt tatttgcgcc
     7021 aggtcatttt ttaaatctgt atgtctatat cgttcaggga tcaatataac agggtgcgtt
     7081 tctttttcgg ttatttggat caaccttcca gagacatcaa tcaaaggaaa tttcttaaga
     7141 taattcagat ttatttttat ccctctgcca aactgttcat tttcttcatt caagtaatct
     7201 gatacattga ctaatatact tccgttttta ttcaaagttt catataattc ctgatcggct
     7261 gctgatgcaa aacgattgga ataaataaaa tccacgtggt ttttcccgat ggttactgga
     7321 taaaatacat gatagtcctc accagcgatt tcttttggtg tttcatggga aacagctaac
     7381 tgtgaagaag aaaaaacgat agttgctaat tcgacattgg caacggtcaa aagaagagaa
     7441 aacaacaatc caaatgtaaa aagaatgtat tggatatagt tgaacgcttc tcttaacgaa
     7501 gcgatttttt caactaataa aagagaaatc aaagagatac cctatattcc gctgaacaag
     7561 aaaacgtaca tctggaacaa ataaagaaat tgctccttat aatacataaa aataaaacca
     7621 ccaatgattc ctgcaattat gaatgtaata atgattttct ttttccccaa taaacaccac
     7681 aatacttgat gtaatgaaaa gccattattc aacaataaac tgatttcttt attcatcaat
     7741 aagaaaaagg atgataacaa aaggaataaa agaatcaatc caatagttaa atacactcga
     7801 taattatata cgtctgtact tgaaataacc gaatacgaat agctattttc aaagtcttca
     7861 aaaatattag tggcataatc agtgtgaaat gcttgattga atcgttccac aaatagtaaa
     7921 atgaaccgtt cataggcttc tttttctctc gtcatcaaga aaaattcacc ttcaaaatct
     7981 tttattttga tcgattcttc aatggacgtt acgcgaaagg aggtattaga atagggtacc
     8041 ttctcgtgag aagatttgac atccccttga taatacaatg tcatttcaag ctttggctgt
     8101 atcttgaagt tccaagatgt atctacttca ttggattcat ttactgtttt tttcatataa
     8161 gaaagctcag tttctgatga gacattttca aataccatga ttagctgctc atattcttct
     8221 tgcccaataa aatgttgtgg caatcgaatc ggagtataag tatctgtttg atggaaaaat
     8281 tcatttgtcc gatagagtac ctgtttattt ataataacca aggcaaaacc actcatgata
     8341 ccggtcacta tgattgtgag taaaactgtg aacttttttt tgattatcac cactctccct
     8401 tacttaaatg attctttgat aaaatcatac cgtttttcat caaaaaaacg tatctatcaa
     8461 atgtataggt catgtagaat aaatctatat actgtagaat cgaaaggaga agaagatgaa
     8521 catcggagaa aaaatacgaa cttaccgcag aaattgtaag cttacgcaaa aagaattagg
     8581 cgaaaaaatc ggtgtttccg ataaaacaat ctctagttgg gaaaattctc gtacaatgcc
     8641 agaccttgaa atgctgtcac ttttacatca gactttaggt ctgccgattg attttccttc
     8701 tattgaatca gctaccgaat caatagaacc aacattgccg gatgaacctc ttgttatcaa
     8761 gaaatcttat tcatcaaaac aacccttctc actcaaaaag acactatctt tctttctgct
     8821 cgtcttttgt ttggtctatc tttttcttat caattatcaa tataaaaatg aaacggttga
     8881 tcgattcaat ccttttttga aaccacaaat cggctatacc acactccctg taggatacgt
     8941 ggaaaattcc atcgaacatt gggtatgtaa tgatatcttt gttcatggta catggctgtc
     9001 ttttcacgct ggagaggtag aaaaaggtaa gaatcatgct gtaatcaaac acaaaggaaa
     9061 acacgtcatg aacgttcgcc tgctcacttg ggaagccatt ccctcagatt accaagaaat
     9121 cctcatccaa gactatgacg atgccttaaa aagaagccct caggagccag ataggcatta
     9181 agtaggagat gaacgtagag atagaaaaaa tcaatgcaca tgatcttatc aaaaaaaaac
     9241 aggggtacaa attaattgaa aaagctttga gatgaaagtt cctaaataaa aaagttcaga
     9301 atgataggta aaaaaatgac taactattct agtattaggc tatttgtatt attcttctgt
     9361 tatttttata tcaaaaaatc cagaaataac taaatatagg tatttctggc ttatagtata
     9421 atatttacgc cacagccccc aatgattctt tttggaatca tgatcaagga cggacataca
     9481 caaaaatatt ttgcccattc gatccgaata gattaacgac taatctagta agtaatatag
     9541 attggtacgt agtcaaacca gcaaatggaa aagttgtcta ttccacccca agggctttaa
     9601 agacagcatc ttccggcgtt tgataaaaaa tcaaattaaa ggtacccatt aattctgggg
     9661 gtacagttcc aatatcagca gcgcttatca taggtacaag tacttttttc gctccggcat
     9721 cttttgctac ttgtaaacag ttagctaaat tatctacctt aatcatagaa ccaccaattg
     9781 taatatcccc taaaataact aaacttggta atacaggttt atttaaggaa actgagcata
     9841 aagctattat agttgataac gataatgttt ttgtcatacc aatgccattc atatcttgaa
     9901 catgaacgac aaaatctttt gtcgtcaaac taatagactg actaacactt ccataattag
     9961 ctcttaaata tcggtatgcc gaatccatcg cttctcttgc tccagcatct gaattgatcc
    10021 cagtacgttc aaactttcca tttcccgaag tcatttgcgt ttccaattta taggtaccta
    10081 attgcccagt tttgccataa gataccgtgt acaaatgccc tggcttccct aacccttctg
    10141 gaatcaaagt tcctccacct tgttcaggaa cagaaacata ctcttctcgc tcttcttcta
    10201 aatcaatgta tgaaaaattg acatcataaa attccattcc accaattttc tttaattgtt
    10261 cttttacacg acgacgcatt tcaagagcaa atcttagtat ttcttcgaca tcactttttt
    10321 caaatctacc atcaggatac aacagtttca tcatcccaga tacaatccga cgaactgcaa
    10381 tcgtatcccg ctgatttaat tgagaaccaa gtttgaaata tttatcaaaa ctatcgccaa
    10441 aactaacttt tcgaagctca cgcatgactt cagaaaaata atctgtaatg aagccatagt
    10501 catttgtaaa aaaatctggt cgatatttag gaatttccca acctggtaaa taacaatgca
    10561 tccgatccaa aaaggctgaa tccgtcccca taacctccgg aaatggctca aataaattcg
    10621 aagttttcaa tattacatca acgctttgat taatatttcc tacaaaagcc attgatgctg
    10681 aagcattctt ttcttctttg cctctagcaa aagatcctga agccatgtaa tctttcatga
    10741 tttgaacgcc atcattatcc ttaaatttaa tcccagcaac ttcgtcaaaa gcaacacagt
    10801 cccacatacc tacaagtccc attgtacgac tagccatatt atagaaaagg tttgctactg
    10861 ttgtttgtcc acctgaaaca aggattgagt ttggtgaaat ttctttatat acatgcgatt
    10921 tacctgtacc acgtggtcct agttcacaga gattaaaatt attttcaatt aatggaataa
    10981 gtcttgctaa atgaagccat tttacccttt tattaaattg tgtaggttcc ataccaatgg
    11041 accgtagaag taagtcaatc cattcatttg tagtaaactc cttgcgagcc atcttgtaag
    11101 cctcaatgtc taaaccaggc atttggattg gatcaacctt ttttgcaata aaagggctat
    11161 tccaacgatc attctcatca taccaatatt ccatcgaaac aatacaccag atccccccac
    11221 ctaataatcg atcaaatttt ttcggatact cttcactaat ttgaacattt tttaatccca
    11281 ggttagagaa ttctgcttca taacaatctt tcttttcatt taaatgtaca gttactttat
    11341 caataactgt ataaccaccc aattcacgaa tttttgcttt tactttttct gcttcatcag
    11401 gacgcacata gtttcgagca agaatatttt taacattttc cacacctttt tcaaccaatg
    11461 tttcatccaa tgacgaagca tacataccaa gtaaatattc caatacataa acaggtacat
    11521 tcgcaccttc tttaattttc tttgttaaat cttttctgac aatctttccg ggaaagaatt
    11581 cagataactt taaaatttcc tgttgttcca ctagaattcc tccatgtgtt cagtcattat
    11641 aatagcaatt aaagtatatc atacttaacc agtaggcttg ataatacaaa agaaaaagta
    11701 tccacaaaaa attgtggata cctcgttttt atatatcaaa atcaaatgat tctgcaaaag
    11761 gattatctat aatgaatttt attcgctcgg tcaaatcatt tttttgattt tttatcacta
    11821 aataataagt atcttcaact gtatatcgac gatttacaaa ttcaaaaaca aatttagtaa
    11881 accgctgatt tgcatcttct gtttttgaat ccgcaacata gatttcttca tttgagatac
    11941 gttcaccata ttcatcttca aaataaagcc agaaagatgc ggggtcataa acatcactaa
    12001 ttgcattttt ttgatagaat tctaacgtgg ttgataatcc tgtaattctg cggttgctag
    12061 tcattaattc aattgctact ggttcctttg cattgctacc tttggctacc gtaatttcta
    12121 gaacagggac tagcatttct tgaatagatg accctccatg aacgtagctt tgtcccccgc
    12181 cagctttctt aaaaatactt gaagtaatcg ggacacaaat gtttctagtg tcatcatttc
    12241 ctaaagaatc tcccaaagag taatttttcg taccaattat ttcgtattct tcttcactaa
    12301 gaataaaacg acgttctaca cgatcttttt catttctaga tggattttca atcttatcta
    12361 cttcttcaac gtggcttctt ttataaataa atccatgatc agccgtaact ataaaacgat
    12421 agatactgcc atcattatgc aagcgattaa taagtcggga aatttcgctt atcgctaaat
    12481 cacaggcctc aaaaactcga ttttcattcg agtgatcacc tgttctatcc acttgatcgt
    12541 gataaatata aatgactgat ttgccattaa atacttctcg tacctcagcc ttattcatct
    12601 taaccacatc atcataattt aaagctacag catttgcatc tcgttgctgg agaatcgcat
    12661 ttcgattgga taaaccattc gtttttttcc catcaatcag tacttctgtt ccttcattgt
    12721 aagttagttg attgtttggt aataaggcgg ctttaccgaa ttcagtaact gaaggtaata
    12781 cagaaagaaa gctagccatg tttgttgaat acttcttttc tctaactaac ttacgttcta
    12841 aattcatccc taactcatat cgaaaagcat ctgaaataat aactacagtt ttaacagagc
    12901 gtttcattac agcttgatta taaaattttc gaatggatgg acgattctta aattcaaaag
    12961 tttgattcca aatttgtcct gattgatcaa gaaacttcga ataatttgct tcaactaatc
    13021 gatacaattg gccatatttt tgcttttctt ctatatgatc actattccaa ataaatttcc
    13081 gataatgcgt atcaacccaa tacatttcct tctcatattg agttagcaaa ttatccatgt
    13141 tcatcggcaa gcacaatctg tttttatcca caagataata agcatgtttc aataattgat
    13201 actcataaat ataatccgat gcgaaatgca ttttttcgcg ctgctttaaa ctatcaaaaa
    13261 ttgtttgtcc tgcaattttc gttgtagtgt cagaagcctt taatcgttct gcataaaaca
    13321 ttaatatttt tgcatgaatc tcagaaaata cgtctgcttc aattagatca tcaatttcta
    13381 tactgtctaa taatccatca ccatcaatag cctgatatac ttttttagat agctgttcaa
    13441 agctttccat gtaacgtgta tcattcataa actgatccat gaaagtaata atgtttgctt
    13501 tcaaatgtag tatttcaaat cctttgaact tcttcggcat ctcttgatca atttgataat
    13561 aaaaatagtt caaataaaga cacatcgtca gcttttccaa tgttggctgg ctatccgtaa
    13621 agccaaattt catttgaata aattcccaaa atttagctgt taactgatac ttatcaagtt
    13681 cccttaaagg attctcccta ctttctgtaa agctttttag aactacacgc agtaaatcat
    13741 ttaatcgaat acttttcgat ttcaacaaaa cagccattat cattaattca atcgtttctg
    13801 atttattaat tgtcatatgc gtactaaatt caccaaaact tctcatgcga tcctttgcat
    13861 taaagaaatt acgatactgt ttaactgtct gatgaaatct aagtggaata gccaattcat
    13921 tcatgataat cgctaagcgg tctgcactaa attcctctga ataattcaat acactcaaca
    13981 aatgattatc ttcatcttta tcatcccaac gaggaaatgg cgcatagatt aaatagttag
    14041 tttcgggatc ttcatattcc aataaacgct tagttttaaa ttgtgcgtcc ttttctaatc
    14101 gatagatttt tgcattttga atgaccaatg agtcaatttc ttcaagaaaa tcctgatttg
    14161 aatcaaacca aaaaatgatt ttcctacatc cataattagg aaaacgttga tttaattttt
    14221 cttcaatttg ttgcgtattt atatctgtca tcaatctcac ctaatcgttc tctttctata
    14281 ccccttatat tgacataatt tggataattt cgcacgcaat ttaagaataa aaaagaaagt
    14341 tgttagaaaa caactttctt agataactat ttttttggtt ctttgacccc ttttgcaaaa
    14401 atttggaatt tctcgccggt tttaggatca cgctgcaact tatcataatt gacaattaca
    14461 ccatcatcta agtctaattc aattcgtttt aatgctaagt gacccaactt ctcgtcatac
    14521 tcacgaactt cttttaattg cttctgaatc tttacaattt cttttgtcat tgcatttctt
    14581 tcttttgggt tatcacttgt tgaaatttgt tgctgacgca attcgattcg attgtcatac
    14641 gctttttgta gttcgtgtag gtattcagta cgtacttttc ctaattgatc tggtgtatag
    14701 cgatgcaagt acattaacgc tttaaagcca ttttgttttc ctgagtccaa ttgccaataa
    14761 attggtcgat tggagtatgt ttttaaatgg tctttgtaaa aatcttgtac gaagtaacga
    14821 cgaataattt ctcgacttgt ccctttgcca cctaaagtgt cagcgataaa ctggagattt
    14881 tcttcaaggg tttctttacc aaaagtaatc tcaacgaaat caatgaaacg attgacaatg
    14941 tcaatttggc tatccttgaa atactcatca tcggtgatga gtaaaacatt atcagtatca
    15001 ggtttaaatt tttgatagcg ggaaggatcc cattcgccgc cagcgaagat gagaccatct
    15061 tcgtctaggg agtaacgacc gaagatacaa cctattgaat aagaaataaa atccttaatt
    15121 tccctcgcct tatcaggtaa ccttgcagag atatattcat cttgaacctc ttttgttaat
    15181 tctttttcaa gagaataatg attaatgaat atgtcgttca gttcctcttc attcgatttt
    15241 agagtattaa attgattaac caactgccta cttagacagt taaatgcctc tgagagatct
    15301 tttttaaaca tataacttaa caaaatgttt cttctaaact cgtatgacgt ttcaagagca
    15361 ttatagtctt ttctagctat atcgatattt tcatccactt tttctcttat tttttttaat
    15421 tttctctcag atgtaacttt aagaaaaggt agttttccca ttggtc
//
LOCUS       DADQDV010000065        15420 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.067, whole genome shotgun sequence.
ACCESSION   DADQDV010000065 DADQDV010000000
VERSION     DADQDV010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15420)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15420)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15420
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.067"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            287..694
                     /locus_tag="J8S10_002253"
     CDS             287..694
                     /locus_tag="J8S10_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630832.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            708..1109
                     /locus_tag="J8S10_002254"
     CDS             708..1109
                     /locus_tag="J8S10_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630833.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            1111..1482
                     /locus_tag="J8S10_002255"
     CDS             1111..1482
                     /locus_tag="J8S10_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630834.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
     gene            complement(1518..1823)
                     /locus_tag="J8S10_002256"
     CDS             complement(1518..1823)
                     /locus_tag="J8S10_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630835.1"
                     /translation="MTIELEEHLLWFKYDPSEKFVKDLYKVWDTEVVFLAIETSLLVN
                     LHYSNKNYFKIPAVKTRMKKGVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(2350..2422)
                     /locus_tag="J8S10_002257"
     tRNA            complement(2350..2422)
                     /locus_tag="J8S10_002257"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2387..2389),aa:Lys,seq:ctt)
     gene            2803..3372
                     /locus_tag="J8S10_002258"
     CDS             2803..3372
                     /locus_tag="J8S10_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HAZ9630836.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            3359..4219
                     /locus_tag="J8S10_002259"
     CDS             3359..4219
                     /locus_tag="J8S10_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAZ9630837.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            4409..5113
                     /locus_tag="J8S10_002260"
     CDS             4409..5113
                     /locus_tag="J8S10_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAZ9630838.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            5118..6953
                     /gene="walK"
                     /locus_tag="J8S10_002261"
     CDS             5118..6953
                     /gene="walK"
                     /locus_tag="J8S10_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HAZ9630839.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            6950..8266
                     /locus_tag="J8S10_002262"
     CDS             6950..8266
                     /locus_tag="J8S10_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630840.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            8267..9136
                     /locus_tag="J8S10_002263"
     CDS             8267..9136
                     /locus_tag="J8S10_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630841.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            9191..10000
                     /locus_tag="J8S10_002264"
     CDS             9191..10000
                     /locus_tag="J8S10_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAZ9630842.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(10103..10732)
                     /locus_tag="J8S10_002265"
     CDS             complement(10103..10732)
                     /locus_tag="J8S10_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HAZ9630843.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            10902..12194
                     /locus_tag="J8S10_002266"
     CDS             10902..12194
                     /locus_tag="J8S10_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAZ9630844.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQQLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(12270..12932)
                     /locus_tag="J8S10_002267"
     CDS             complement(12270..12932)
                     /locus_tag="J8S10_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAZ9630845.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            13157..13441
                     /locus_tag="J8S10_002268"
     CDS             13157..13441
                     /locus_tag="J8S10_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HAZ9630846.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            13492..15117
                     /gene="groL"
                     /locus_tag="J8S10_002269"
     CDS             13492..15117
                     /gene="groL"
                     /locus_tag="J8S10_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HAZ9630847.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         5225 a         2572 c         3218 g         4405 t
ORIGIN      
        1 tgaggggaag tacatatagt tgttgatata gttgctaata ttgttagcta atttgttagt
       61 aaaactgtat acgaatttag atagtaaaaa aacagtttgt tccttatata gaggcacttt
      121 tactactgat taaatgtcag atatgcttac aaatatactt ataaatatgc ttacaaaatt
      181 agctaatatt tccgttgaca aagctttgtt actattgtta aactaaattg actagcaaaa
      241 gtgaaacata aatttattaa ataaatgtaa aaattaggag aaatcaatgt cttatagagt
      301 acaattaata atttcagaag atgtagaaag tcagcaattt ggcactaatg ttattaataa
      361 agtaattaat ccagctcttt ctattaatgc gcctttaatt cctactgctt tatcattttc
      421 tgtaacagct gtggtgtctg agatagagga tacagaaaag ataaaaatag tagaaattga
      481 agttttaaac aagaatgaaa aacaaatttt ttctacgggt gaagtatcgg taagcttgcc
      541 tcctcaagtt aacgatataa actttaatat aaacgccaga aatgtcttgg ttgaagaagc
      601 aggagagcat tatgctgttg ttaaatttaa tggaactgag attggaaggc aaatctttga
      661 tatcaaggtc aacaaaccag tggaaaaaaa ttaaggagac gatacggatg cttgatatag
      721 taccatcaaa tacacatcgg agtggtagct taataaattt tgctgcgatt tttgcttgcg
      781 catcggtaat tctagcatct ccagttgttg tggatgcaag ttctactccg aaaactaaaa
      841 atgataatca acttgtaatt actacaaaaa atgagattaa cacaatttca agtaatgatg
      901 gcaaaatttt tgatgtgata aatacggttt taaaaagaaa agctgaaatc aatataaaat
      961 atgatgaaga tttaaacttg tatttctttg ttatcaaaac aacatctgaa ttgttttcct
     1021 cagattacga tgttttggat actctcgata atgtattatc tgactataaa tatatgggga
     1081 aatctgtagt agcaactttg ggggaataaa atgtttgact ttaatgaata tttatctatt
     1141 tccaaacaaa ttgaatcaga tgataaatat aattctaaag aatcttatag aagaactgct
     1201 gtttcaagag catactacag tgcttttaaa aaatctgatg agtatttgaa agaaaattat
     1261 gatattattt ataatggaag tagcggaaaa ggaagccacc aaaccgtttg gaatttgttt
     1321 tcaacagtta aggaattgaa taccttagga atacataata gtgggtatag aatgttagag
     1381 aaaagaaaat gtgctgacta tattcctaat gaaaccatta cgaaaacaga tatggcgctg
     1441 atgaatcgag aagcagaaaa aataataaac aaactcacct aatgaatttc aagcgagttt
     1501 gtttgttatt tttttattta atctttgtat ctttctggat caacgaaagt atactttata
     1561 tagtcataac gccgatgatc gctacgtgcg tccggcacgt cagtcacgat atcaaacaaa
     1621 aagtatacac ccttcttcat tctcgttttc acagcaggaa ttttaaagta gttcttatta
     1681 gaataatgga gattgactag caggctagtt tcaattgcta aaaagactac ttcagtatcc
     1741 cagactttat ataaatcttt gacaaatttt tctgatggat cgtatttaaa ccaaagcaga
     1801 tgttcctcta gctcgattgt catgtttttc acctcaacga aagtatacga actaatgttt
     1861 gttttgtaaa ggataaaaat agggtagcaa ccggtaccca aactagtacc catttatcaa
     1921 aaacgacgaa atttatgtaa atagaaaaat aagaataaac attgatgtat caacatttat
     1981 atatctttag aacaaatgaa aagggtggtt ctcataagaa aaacatgttc gcacttctag
     2041 gcaaaccagg atttgaagac cttgctaaag aattgaacga acgcctgtaa aataaggatt
     2101 tgtcgctaga tttaaaaaat cagtgataga aacatgtttg ctttaaaatg aaactagtga
     2161 tagttttagt gatagtgaac ttaaaaaaag cactcaattt gagtgctttt ttattgttat
     2221 taaaaattaa aaaactaaaa tacatacccg aatttcatac ccgaaatata aaaaatgtca
     2281 tcacgtacat ctttttcgaa actaccgaag tagccaaaga tgtactgatg acgtgggttt
     2341 ggcacccaat gggccgtgag gggctcgaac ccgcgacccg ctgattaaga gtcagctgct
     2401 ctaccaactg agctaacggc ccgtacaaaa agtacttaat aatagtagca ctaagaattt
     2461 taaaatgcaa gactacattt aaagaaaatc agaaaaatct ttacttcctt ataggaaatc
     2521 attcatagat tattcacatt tgctcgctat tatataagca taccaacaaa caaagttctt
     2581 gcaagagaac aaaccctaac acttttttca ttttttactc ctttcccgcc gtctccccgg
     2641 cgggtctcct gttcttaacg ataaaagaca agaaggctta gccttcttgt tttttgtttt
     2701 catggaatcc cgctaatcaa atcacctagt taaagcaact agattgaatg tttatcataa
     2761 gtctgatatc atgtttatga aatgaaaaaa ggagcggtta tgatggaaaa aatgcgtcag
     2821 caattaatgg agtgggggaa ggaactagaa acattccgtc tgcctcactg ggaagaactc
     2881 cctgacttag aactttatat ggaccaagtc agaacgttag ttgatcgtta tctttcacct
     2941 gtgatacaag gagaaaagca tccattgctt acctcttcta tggtaaacaa ttacgttaaa
     3001 ctaggtttga taccagcacc agttaaaaaa agatataaca aagaacacgt agcattttta
     3061 cttgcaatca ctacgttgaa acaagtattg actattcctg aaatcaaaga agggatattg
     3121 ttccaaggaa aaacagtagg aattcgtgaa gcctataatc tattttgcga tgaacaagaa
     3181 gcagctgtgt ggatggtcag ccaattagca caaggtaaat ctcatccgca aaaattcgac
     3241 caggcaaccc ctgtagaata tattgctgta agagcggcaa ctttatcgtt tgcaatgaaa
     3301 cttcttgcgg aaaaaacgat tgttctagaa accgaatatt taaaagagga gaaaacaaat
     3361 gaaaaacaat aaaatcgcaa ttttagtaga ttcaggtacg gatgtgccag aagaattgat
     3421 aaaaaaatac gagatgtata tgatcccatt gaaaattatt tataaagatc aggtatatac
     3481 agataaaatt gacattacct ctgaagagat ctatcaacgt ttgccagagg aaatccctgg
     3541 tacatctttg ccggatggtg agtcgatcac agaaatcttt gagcaaatca aaaaagacgg
     3601 ttatgaaaag gtacttgcgg taacaatttc cagtggattg agcgggacat ataatgtggt
     3661 tcgtttaatt gcacaacagc aagaagaatt ggaagcatat gtactagata cgaaaaatat
     3721 tggtattggt gcaggttttt ctgcgatcca agcagcaaaa tggctggaag aaggagtaga
     3781 atgggatcaa ctgatcagta atctgaatga gttagtcgaa agaacaaaag ttttctttaa
     3841 tgttgcgaca ttggaatatc ttcaaaaagg tggacggatc ggtttagttg cttctattgt
     3901 aggaaccgct ttaaagctta acccaatcat ctcatgtaat gaagaaggga tttattacac
     3961 agtaggaaaa gctaggggac gtaaaaaaag tttggataaa acggttgctt acgtcaaaga
     4021 aaaaatcggt aatgcaaagg tcttcaactt agctgttgcc catggggatg cgaaagaaga
     4081 agcaattgaa atggaagcga gacttaaaag agagttccca caagcaaacc aaatctactt
     4141 tggccagatt tctccggcat tagtagtcca cactggtccg ggattattgg gtgtcggtgt
     4201 acaagtttta gaaggataaa tcaaaaaaag gaaacactga ggtgaaaatc agtgttttcc
     4261 ttttttattg aagttagaac aaaaaataat aaagtatttt gcactttcat tttaattttc
     4321 tcttttgttt tataggcaaa gatgaaacaa aagcagaaat acggtataat gagaaggtat
     4381 gacaataata tataagaggt ggctctttat gaaaaaagtt ttagttgtcg atgatgagaa
     4441 gccgatttcg gatatcgtca aattcaattt agccaaagaa ggctatgatg tttatactgc
     4501 atatgatggg gaagaagcct tggaaaaagt tgctgaggta gaacctgatt tgattttact
     4561 tgatttgatg ctacctaaaa tggacggctt agaagttgct cgtgaggtac gcaaaactta
     4621 tgatatgccg atcattatgg taacagccaa agattctgaa attgataaag tcctaggctt
     4681 agagttaggc gccgatgatt acgtgaccaa gccattttcc aaccgagaat tagttgcacg
     4741 tgtcaaagca aatcttcgtc gcggtgccac ggctgcgaag gaaccagaag aggcagcacc
     4801 tgcggaattg acgattggtg atttgacgat ccatccagaa gcttacatgg tgacgaaacg
     4861 aggagaaaca atcgagttaa cacatcgtga attcgaacta ctcttttact tggcgaagca
     4921 ccttggacaa gtgatgacaa gagaacattt attacaaacg gtttggggtt atgattattt
     4981 tggagatgta cgaacagtgg atgtaactgt acgtcgtttg cgtgaaaaga tcgaagataa
     5041 tccaagccat ccaaattatt tagtgacacg tcgtggtgtc ggttactatt tgcgtaaccc
     5101 agaacaggag taattggatg aaaagaaaag tccgcttttt tcgatcagtc aattttaaga
     5161 tcgctattac ctttattctg attttattga tctcgatcga aattattggt gcctacttta
     5221 tacgtggttt agaacgttcc acgatcaata catttattaa agatatgaat caaacggtgg
     5281 aatcattagc aacaacaatc agcccggaat tgaatcgaaa agataatgca gatgatgaag
     5341 aggtaaatgc gaatatcaaa agatttattg aaaacagtgc gactagcgat atcatcgaaa
     5401 tacgggtcgt tgacgaaaaa gggatcatcc gaggaacaac cgatgtcaat gaacaaagcg
     5461 ctgtgggaaa gaaaaatgat tatgttgata tcaatgattt cacgactaaa cgttatgttg
     5521 ctttagataa cgacgataaa cgggtgaata tcaatgttca accgatcctg tccccgaccg
     5581 gcgatgccgt tatcggggct ctttacgtca aaagtaatat cgaacaaaaa tattcggaaa
     5641 tcaataacac agcagtcatt ttctttactg cctcactaat tgcggcattt atttcaatga
     5701 tcgtatctgt tttagttgct cgttcgatta cacagccgat cggtgaaatg agagaacaag
     5761 ccattcgaat cgctagagga gactacagtc ggaaagtcaa agtgcatgga caagatgaac
     5821 ttggacagct ggctgatacc ttcaatcagt tagctgaacg tattgaagaa gctcaagata
     5881 caatggaagc tgaacgcaat cgtttggata gcgtgctatc ccatatgaca gacggcgtca
     5941 ttgcgacaga tcgcaggggt aaagtcatta cgatcaatga tatggctgtt tccttgctag
     6001 atatcaaaaa cgaggaagca atcggacaat cgattttgac acttttagat atcgaagaag
     6061 aatatacgtt gcggaaatta ttagaagatc caaacgaaat ggtacttgac cgttcaacca
     6121 gtacattgga aagtgatcag atgatcttgc gagtagactt ttctatgatc cgtcgcgaat
     6181 caggttttat cagcggatta gtagctgtct tgcatgatgt gacagaacaa gaaaaaacag
     6241 aacgggaacg tcgtgaattc gtctctaatg tttcccatga acttcgtaca ccgttgacaa
     6301 gtatgcgtag ttatatcgaa gcattgagcg aaggtgcgtg gaaagacgag gaagtagcac
     6361 caaatttttt gaaggtaacg ctagatgaaa cagaccgaat gattcgaatg atcaatgacc
     6421 tcttaaatct atctcgcatg gatacaggta atacccagct tcaattagaa tatgtcaatt
     6481 tcaacgagtt agtgaatttt gttcttgacc ggtttgatat gatggtggga aatcaggaaa
     6541 aaaattataa gatccgtcgt gaatttacgc aaagagatct ttgggtcgaa gtagatacag
     6601 ataaaatcat ccaagtagtc gataatatca tgaataacgc gatcaagtat tcaccagatg
     6661 ggggaacgat tacttgtcgc ttattagaaa cgcataataa cgtggtttta agtatcaccg
     6721 atcaaggatt ggggattcct aaaaaagatc tgaaccgagt gttcgagcgg ttctatcgag
     6781 tagataaagc acgtgcaaga gcacaaggtg ggacaggact tggattagct atttctagag
     6841 aagtgattaa ggcgcatcga ggcgctattt gggcagagag caaggaagga aaagggtcga
     6901 ctttttatat ctcgctgcca tatgaacctt atgaggagga atggtgggaa tgagaatctc
     6961 tgaaaaagtc gttcgtatag gactcatttt gatggttgcg ttaagcatat acttctctta
     7021 tgcaatctgg ctgagcccag caggaaaaag ttcaatcaac gtagatgaga caaacactca
     7081 aatgatcgag tctcaaagca atcgaaaaac ttccgaagtc tttcttccgc ttcatgttac
     7141 atggcaccat tcgggaatga tccaagaaac caacagtgaa aatctcgtgt accgattgca
     7201 attgatcatc gataaagcaa gatttggaaa gctttctgaa gtagtttcag gagacaaatc
     7261 acagtttgaa caggtgaaaa atctgaactc tggttttgag ttggcctata atgcgccttt
     7321 tttgctaaga gaatacaagg aagcatttga tttagattta gatgtgtcga acttggcaaa
     7381 agaaagcgaa aatatgtatt ttactagaat acaattcgat caaggaaata aaaaaatccg
     7441 atttttgaat tattcgaacc atctcgtata tgaagcaaat atttcgttga attggacaga
     7501 tatcaataaa gaattaacag caaaagacac aaaatggaca gaaatgacaa cagaaccatc
     7561 gacgatcgac acgcaatatg ctacgaaaca ttcgatcaaa ctgaaaaagt atagttatat
     7621 cctgtcacag caaccctata cactttttag aaatgctttt ttccagaaac cagatagcgt
     7681 gaaaaataat gatgaaagca atgaattgat tttttacggt gggaatgaaa caatgtctat
     7741 ccattcggaa acgcaagtag ttgattttcg tggagagctg ccagagaaaa aagaaaatgc
     7801 tagtgtattt tctgaaagtt tcccctatat tagcaaatta ggcagttctt tagggaacct
     7861 cagatatttt gaccgcagtg acaatacgat cgattatcgg atattcgtgg aaggcttccc
     7921 ggtttttggg acagacagca gaggacagat tggtgtggaa gttggcggtg aaacgaatgg
     7981 ttctgtgcaa gtgaatatcc aaaccagttt gaatacgatt caagtgccga taccttcaga
     8041 cgaagaagta gaacttgcaa gtacgaatga aatcatccag cagttaaaag ctaagggagc
     8101 agatagcaac aagattggtt cagtgatcgt tggctataca tggcaaaatg tcaaagaaac
     8161 gaatcgtgtc gttgatctct tacctgaatg gtatgtgaaa tataaagata actggtattc
     8221 agctaacgac cttctggaaa aattacctgg attggaggcg aattaattgg atttcaaaaa
     8281 aatcgaatgg atatttttcg tcgctttttt agggttgaat gtgtttttat tcagcagtta
     8341 tcatgacgcg gtataccaag aaaacaatgt cattcgctct aatcagactg aatcaatcca
     8401 acaacgtctg gctagcgacg atatcactta cacggggaag atttcgtctg agaacaagca
     8461 aggctattat cttagcgcgg agcagaccaa tcttagcact tcattagcga attatcgcaa
     8521 ggctggtaaa agcggcttgc tggcaagtgg tgtgttttta gacggtgatg ttttgacgaa
     8581 atctttatcc agttcagatg ctgaaaagaa cgtgatcgat ccagataaaa ttagtagttc
     8641 cttggaagat tttttatcta acaaagacaa tattttattc ggtaatgatt atgtgtacac
     8701 gaaaaacttt tctcatttag aagaagaacc actagaaatc caagcaagcc aagagtatga
     8761 aggcatccca ttcaatgatg atacagcaaa aatcgttctt tctttagaaa aaaacgataa
     8821 tgattatagc atcacgaaat acatgcagac gcatttatct gatatcgagc agctgcgcga
     8881 aaagacggaa ctgtatacgg aagaggaagc aatcaataca ttgtacatca ataacaaaat
     8941 accaagagga tcaaaaattt tatggcgtca gctagcttat tcctgtattc tgaaagtccg
     9001 ggaaaaaaat gtgtatgttc ctgtttggca tgtagcgatc gaaacaagcg ataaagtggt
     9061 ccaaattgag agtgtcaacg ctttcagcaa tacgatcgtg acaaacaata ctgtaccaaa
     9121 agtggaagat caataaaaaa gcgagtataa tgaaaaaagt ttacaaagta agaagggaag
     9181 taggagtcaa atggctgaag aaaaaccagc ttttaaaatc agtatcctag caagtggaag
     9241 ttcgggtaat tcactttata tcgaaagtga aaaaaaacgg cttttggtcg atgcaggact
     9301 tagcggtaaa aaaatcactt ccttgatggc tcaaattgat cggacaccgg accaattaga
     9361 tggaatactt gtgacgcatg aacatcgaga tcatatacat ggcgtgggtg tcttggctcg
     9421 taagtatcat ttggatgttt ttgccaatca gcagacttgg gaagcgatgg aaccactgat
     9481 tggaaatgta ccagtggaac aaaaacatct atttgagatg gggaaagtca gaacattcgg
     9541 cgatatcgat attgagagtt tcggcgtctc ccatgacgca gcggctccgc aattttatcg
     9601 tttccataaa gaaaatcggt cattcgtcat gttgacggac accggatatt gcagtgatta
     9661 tatgcgaggt gtcattgaaa atgccgatgg ttatttgatg gaaagtaatc atgatcttga
     9721 gatgttacgc atgggacctt atccgtggaa tttaaaacag cgtattttag gagatagagg
     9781 acatctttcc aacgaagacg gtgcacttgt catgactgat gtgatcggta atcggaccaa
     9841 acgaatctat cttggccatc ttagcaagga aaacaatatg aaagaacttg ctcatttaac
     9901 aatggaaaat gttttgaaag aaaaagattt tggcgttgga catgattttg aaatctatga
     9961 tacagatcca gatgaagcaa ctgagctatt ttcgatttaa acagttcaat caataaaaat
    10021 ataaaaagca gaagataaaa tcaatcaggg ttggttttat cttctatttt tattttttta
    10081 gcatattaaa aaaataaccg tattatcgac tgactacact gatgtgctgc ttttcatgtt
    10141 tctcatccag tatctcatct actaatgcaa tcgcgtaatc tgccatgctg atcgtactgt
    10201 cgccagcagc gtttctttgt aaataatcat cacttaacaa ataagtacct gtacgtttgc
    10261 catgtggatc aaataaagaa gctggactga tataagtcca atgtagattt ttagattgtt
    10321 tcaattttaa caatccttcg tacatattga aagctgttgg atagaagggt gcatttttag
    10381 gtacttggtc aatcatacga gtcgtctttt ctgtatctaa gaataacgaa gaggcacccc
    10441 caacgacaat taagcgtgta tcggttcctt caagcatctc aatcaaatgg gacaaagaag
    10501 tttgatgcat ttcttctttt cctttgggag cgttgaaagc atcaacgaca acatcaaaag
    10561 atgcaagatc agtagttgtc aactcaaata aatccttttg tataaacgga acatctgatg
    10621 gcaatttttc tggatgacgc acgattgccg tcacgtctaa atctctggac aatgcttcgt
    10681 ctaaaataaa tgaacctgca tggccagtag ctccaatgag tgcaattttc ataaaaaacc
    10741 tcctttttta ttcctgtcca ttgtaagcag ttgctgaata ttcgtcaaag aatccgattt
    10801 ttgaaaagct cagtgcgcat tcctttcatg gttcgtgatc attgggtata gttaaattaa
    10861 gaaaactgat tgataaaaat agaagttgaa ggagataaga aatgaaagag tggttagatc
    10921 gtgccttttt accaatgata acatctgttg tgaatcttag acccttaact gctttgcgta
    10981 atggaatgac ttacacgatc ccaataatta ttgttggctc gctgtttttc ttatttgctc
    11041 attttcctgt ggattacatc gctcagtgga tagacaaaac aggattttct atgtatttta
    11101 cacaagtata ccaggctaca tttgatgtga tagccttttg gatcgttttt gccattgcat
    11161 acgcttatgc aaaagaagaa gacatcgatc gcttaccagt cggcataaca gccttgtctg
    11221 cttatctact gcttattcag ccactaaata ctcagataga tactgtctgg acaggtgctg
    11281 aagggatact aggagcagtt acaactgggc tcatcatcgg atggggctat gcacgtttag
    11341 taagacttgc gaaagggtgg aagcaaagag agaagatacc tgaaaatgtt tggcagtctt
    11401 ttacttcatt gattccaatc attgttatag tcacttttac gcttatcggt tcagcggttt
    11461 ttcaacagtt gttcagaatg actgttgttc aaggagtatg gacatatgtc cagcttccca
    11521 ttcaatcgtt catagacacg ttgtttggtg tgcttttatt aggttttttt gttccgtttt
    11581 tatggttatt tggtcttcat ggatctgcga tggtcaatgg gttggttagt cccgtcttgc
    11641 aagcgaattc attagcgaat gcagaaatct tagcctcagg acaagagttg acggtggcaa
    11701 atggcggaca tatcgttact cagcaatttc tcgatcagtt catgacggtt acgggtgctg
    11761 gattgacgtt aggggctgta ttttttatga cggtttttgc gaaatcgaag aaatacagag
    11821 aattaggaaa tcttgctctt ttaccagcct ttttcaacat caatgaatca attatttttt
    11881 ccacaccgat cgtgatgaac ccgatgatgg ctgttccttt tattttcgca ccggtcgttt
    11941 caggattgat tacctattcc gctttatatt ttggattcgt tcctttattt acagcagtcc
    12001 aagtcccttg gacaacaccg ccgatcctct cgggtttctt agtaggcgga gtgcctgcag
    12061 cgattttaca aggtatcgtg ttgtcaatta gttttttcat ttatttccca tttttgaaaa
    12121 aaatagattc tgcaaactgc aaaaaggaaa gacagacaaa aaatgatgga gcagcagaaa
    12181 agatgaacga ctaaaaaaca aaaatactcc tgtcgcttta gattgggaaa atcaccaatc
    12241 taggatgaca ggagtattta tagtcatgtt tatactagcc ctttttggac agctaattga
    12301 acaagaacaa ctaatgtgtt cattcctacg tgtgtgatca tcgatgtcca gatccgacca
    12361 gttgctttgt actctaggct gaagaagaaa cctaggaaaa agtagattag cagatgacca
    12421 tcattatgag caaacgcaaa cagcaaagag ctgatcactg ctccgaccca aaaatttgaa
    12481 tatcgactga tgatccccag tatactgcgg cggaatacga actcttccat gatgggtcca
    12541 gcaacagttg tcgccaaaat aaaagcgggt gcttccatga tcatctggat gatattttgt
    12601 gtattctcgg aaggggttgc tttgccaaac aatacagatt ctaacatgac agcgatgctt
    12661 tgcagaatca atgcgacaaa gattccaacc aatccataaa taacaatctt tggagcagaa
    12721 gcttttttta ccgctgattc gatcgctaag ggttcacgtt gcttaaaata aaaaatagct
    12781 aggacaacgg cgcctagtat atacatgact gcagttgctg tgatcaattc agacgtagat
    12841 tttacaagtc ctatcgaagc taggatcaag ggtgagataa aaattagacc atagcaaaaa
    12901 atgctgagga agctatattt ttttaaagac atgtaattcc tccttttaag ggataacaag
    12961 catgcaaggc aagcttatat cgattgattt caattatatc ataatttcaa taagcagctg
    13021 tcagaataaa atttcttttc tttgatttaa aagcttgcaa aaaagaggga gaatgagtat
    13081 tattaaaaat gtaggttagc actcgaaggt taagagtgct aacagattaa aaaaagagtt
    13141 atcggaggga tttatcgtgt taaaaccatt aggtgatcgc gtcattatcg aagtcgcaaa
    13201 agaagaagaa aaaactgtcg gaggaatcgt tttagcttct gctgctaaag agaaacccca
    13261 aactgggaca gttgttgcag tcggtgaagg ccgtttgtta gaaaacggtg aaaaagttcc
    13321 tgccgctgta aaagcaggcg accaagttat gttcgaaaaa tacgccggta cagaagtaaa
    13381 atacgaagga aaagaatatc tgatcgtcgc aggaaaagat atcatggcga ttgttgagta
    13441 aatttggaag ataaaaaaat aatcaaaaat aatcaatgag gtgaatcaat catggcaaaa
    13501 gaattgaaat ttgcagaaga cgcacgcgca gctatgttac gcggggtaga taaattagca
    13561 gatacagtga aagtaacatt aggacctaaa ggccgaaatg tcgtactaga aaaatcttac
    13621 ggctctccat tgatcacaaa tgatggtgtg acgatcgcaa aagaaatcga attagaagat
    13681 cattttgaaa acatgggtgc aaaacttgta tcagaagtag catcaaaaac aaatgatatt
    13741 gcaggagacg gtacaacgac agcaactgtt ctgacacaag caatcgttcg cgaaggttta
    13801 aaaaacgtaa ctgcaggtgc taatcctcta ggcattcgtc gcgggatcga attggcaaca
    13861 aaagcagcag tcgaagaatt gcataatatc tcaactgttg ttgattcaaa agaagccatt
    13921 gcacaagtag cagctgtttc ttcgggttct gataaagttg gacatttgat tgctgatgca
    13981 atggaaaaag ttggaaacga cggtgtcatc acaatcgaag aatcaaaagg gatcgaaaca
    14041 gaactagatg ttgtagaagg tatgcagttt gatcgtggtt acttatcaca atatatggta
    14101 acagataacg acaaaatgga agctgttcta gaaaacccat atatcttgat cacagacaaa
    14161 aaaatctcta acatccaaga tattctgcca ttgttagaac aaatcttgca acaatcacgt
    14221 ccattgttga ttattgctga cgatgtagat ggtgaagcat tgccaactct tgtattgaac
    14281 aaaatccgtg gaacattcaa cgtagtagct gtaaaagctc ctggtttcgg cgatcgtcgt
    14341 aaagcaatgc ttgaagatat cgctattttg acaggtggta cagtaattac tgacgatcta
    14401 ggtttagaat tgaaagatgt aacaatcgaa aacttaggaa atgcttctaa agttgttgta
    14461 gataaagaca atacaacgat cgtagaaggt tctggagaaa aagaagcaat cgaagctcgt
    14521 gtgcaattga tcaaaaacca aattgctgaa acaacttctg attttgaccg cgaaaaatta
    14581 caagaacgct tagctaaatt agcaggtggt gtagctgttg ttaaagttgg tgcagctact
    14641 gaaacagaat tgaaagaatt aaaattacgc attgaagatg cattgaatgc tacacgtgcc
    14701 gcagtagaag aaggaatggt ctcaggtggt ggtacagctc tagtgaacgt tatcagcaaa
    14761 gtttctgctg tagaagcaga aggagacgtg gcaacaggta tcaagatcgt tgttcgtgct
    14821 ttagaagaac caattcgtca aatcgctgaa aacgctggtt atgaaggatc agtgattgtt
    14881 gataaattga agaacgtgga actaggcact ggtttcaatg ctgctactgg agaatgggta
    14941 aacatggttg aagcaggtat cgtagaccca actaaagtaa cacgttctgc cttgcaaaat
    15001 gccgcttccg tttctgcctt gttattaacg acagaagcag tcgttgcaga taaaccagaa
    15061 ccagcagcgc cagcagctcc tgcaatggat ccatcaatga tgggcggtat gatgtaagaa
    15121 aaagcaactt gcttatctac aactgatcat tagtgaaaga cagataaaaa gaggctggaa
    15181 cagaagcgtt taactccaag aaataagaag aaattcacgg aaattgcttt tcaaattttt
    15241 gtgaatttca gcttatttcc gaaggagttg cttctgcttc cgctgtttat acgtgtttag
    15301 agcgtgagac aaaagtgttc tttacttttg tcccacgctc ttttttgtgt gtaattataa
    15361 tgaaaatagt tatttttaat agttataata ttttatctat taaaagtaaa tatccattca
//
LOCUS       DADQDV010000066        15229 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.068, whole genome shotgun sequence.
ACCESSION   DADQDV010000066 DADQDV010000000
VERSION     DADQDV010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15229
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.068"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            278..787
                     /locus_tag="J8S10_002270"
     CDS             278..787
                     /locus_tag="J8S10_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAZ9630848.1"
                     /translation="MVQGIERGVYVVDKIQFNQVIEEFIKVNNLMTHIQKRPIRITND
                     LKLSTSMIHLIDVIGNYPETSITELADRLGVTKGAVSQQIPTLEKMNLISISQKKGNK
                     KTKLVSLTKYGRKVYESHNYLHEELYSSINEALESFSPDQISTIKQILEKVSYTINEY
                     QVSLTRKED"
     gene            880..2042
                     /locus_tag="J8S10_002271"
     CDS             join(880..1156,1156..2042)
                     /locus_tag="J8S10_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAZ9630849.1"
                     /translation="MSRRQRRTYSKEFKQQVVDLYLAGKPRAEIIRDYELTTSAFDKW
                     VKQAQTTGSFQEKDNLIPEQVELIALRKKNKQLEMENDILKQAALILGPKRQVIDTNK
                     HKYSISAMCKVLNISCQTYYYQAKPVEDESELEELVQEEFIRNRKAYGTRKLKQCLAN
                     LGLQVSQRRIGRMMKQRGLRSTYTLAHFKFHSSTCNEAKTANILDGTFLQEKSLEAIV
                     TDLTYVRVGKKWQYICLILDLFNREIIGYSCGEKKDATLVKEAFAKIPYSLNNVQLFH
                     TDRGKEFDNQTIDEILWAFNITRSLSKKGCPYDNAVAESTYKSVKVEFVHQYRFETLA
                     NLRLELFDYVHWWNTIRLHGTLGYETPISFRQQRLAQRILDNELGCDTGGEAP"
     gene            2322..3302
                     /locus_tag="J8S10_002272"
     CDS             2322..3302
                     /locus_tag="J8S10_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAZ9630850.1"
                     /translation="MKKIGIREVAKEANVSPTTVSRVLNDRGYLSEETKRKVFDAMKK
                     LEYYPNELARALFKNETYTVGLIFPTITNPFHAELIQDIEFELSSRGYKVLLCNSLNN
                     PTKEKEYLTMLRKNQVDGIIVGTHNKDIADYDIPGLPIVAIDRSLGENTVTVSCDNYR
                     GGELATQLLVNHGCQNILCIRGDSKIKLPANSRTLAYKDVLNKFMLEPLVLEVPFVKE
                     INEKNEIIKTYLETHPNIDGVFAGDDLLASLAINNLGSSGKRVPKEVKVIGFDGAQQT
                     LIYNPELSTIQQPIDQISKVAVKKLLNMIKGEKETDELSLPVKLIKKNTA"
     gene            3424..4842
                     /locus_tag="J8S10_002273"
     CDS             3424..4842
                     /locus_tag="J8S10_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-fructofuranosidase"
                     /protein_id="HAZ9630851.1"
                     /translation="MEKLLIKSNNHQLYYQPKDVWVGDVMPYGKEGKFFIYHQRDTRN
                     PVPFGEPFGWALATTKDFVHFEDFGESLLRGDDNERDQFIYAGSVFEANGKVHAFYTG
                     YNREFLAQGKTSQVLLHAESDDFVHWEKSETALELEPQEGYDIRNWRDPFVVWDDEKE
                     EYLLILGARKGQDKHLQTGRLVEFTSKDLTNWEFKGDFWAPGLYTMFEMPELFKIGDW
                     WYLVYSEYSDGNKILYRMSQSLEGPWIKPKDEAFDGRAYYAGRTAYDGKRRVLFGWVP
                     TKDQENDKNNYLWGGTLVPHEVYQKEDFSLGVKPIDEVWNAFINLHDIADVEIETADT
                     REEVTLVKNSGTLFNLETTISFDENLSDFSLRLYKNLETDESYEYRFNLDEGRLTFDK
                     NPCYPWFQYMDKGLIRPISLKPNQSYKLKVIVDDNIMTLYIDGIALNARVHGCFGQAI
                     TITATNGSMTAINTKFSNEIKK"
     gene            4913..6382
                     /locus_tag="J8S10_002274"
     CDS             4913..6382
                     /locus_tag="J8S10_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAZ9630852.1"
                     /translation="MDYKKIAEDVLENVGGKENISSATHCITRLRLILKDKSKANMEM
                     LEEIEGAKGVLFNSGQLQVIFGTGIIEKVYKEFVELTGAKEVSVSEMKDEGVNNSGNR
                     LQRAFKVFSDIFIPIIPAFIGAAMVLGIRSLITTPGMFGMDGSFADHNVFLNDLSKFL
                     GIIATTFDYLPVLVMYSATKRFGGNPILGLLVGFVMIHPGLANRNDFVMGTIKPDYWH
                     LFGLSIPAVAFQGGVFPAILTSWFLAKVEKITNKYSPQVLAYILVPTVTIVLANFALF
                     LVFGPLGNFIGNVLGGIIDFLYMKMGAFGAFVFAGALQPLVVTGTQHAIQGIEANLVA
                     TTGFNYIQPIWSVSIIAQGGGCIGMYLLFKKKSKDRDIAISSFIPTLVGITEPAIFAV
                     NLKYSIVPFVCSFIGAGFGGAFMKIFDVKAIGQGLTVLPGLTIANPVLPYIFGNLIAF
                     ILPIIFILAYDKYKVFIPEAKHRKFAEKTDSKKLPVQVK"
     gene            6392..6859
                     /locus_tag="J8S10_002275"
     CDS             6392..6859
                     /locus_tag="J8S10_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HAZ9630853.1"
                     /translation="MLNFFRKNEISVVAPATGVFEKLEKLSDPVFSKGMMGQGFAIDA
                     KNETIVSPIDGFVSSIFPTKHALGIKTKSGIEILVHVGIDTVELNGEGFDIKVQEGQK
                     VKAGDILMTINFVVFEKNHKTKDVIVVFPDYQDEIFIPKLEEVKQGQELFVLG"
     gene            6895..7767
                     /locus_tag="J8S10_002276"
     CDS             6895..7767
                     /locus_tag="J8S10_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAZ9630854.1"
                     /translation="MVFGAIEAGGTKFVCAIGDKDLNIFEKVSFPTTTPKETMNLVLD
                     FFNHHKDDLEGIGVGSFGPIDIHCESKTYGFIKSTPKLAWQDFDFIGSLKKQLNIPTA
                     WTTDVNASCYGEYVSGNGRGLSSVVYYTVGTGIGGGAIQNGNFIEGFSHPEMGHMLVK
                     RHNKDNFSGTCPFHGDCLEGLAAGPAIERRSGKKGQEVTENDVTWEIEAYYIAQCAYN
                     TTLMLSPDVIIFGGGVMKQKHLKKKVQDKFIELINGYVAIPDVDNYIMTPKLLDNSGI
                     VGCLALARDVKEKS"
     gene            7848..10382
                     /locus_tag="J8S10_002277"
     CDS             7848..10382
                     /locus_tag="J8S10_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAZ9630855.1"
                     /translation="MKKKMKDEVLEYIKNNLKYYDFSAQDIAMKFCIKRNVASHYLNQ
                     LFSDGKLLKNDSVRPVMFKYNQQKPKDCFSKFIGADISLKSTIDKCKATVMYPPNGLP
                     LIIKGNSGVGKSFLASLIYQYALDRKVIHNDAKFVVVNCADYANNPELLSAVLFGYKK
                     GAFTGAEKDTAGMLSSANGGYLFLDEVHNLSAENQEKLFLLMDSQKYRKLGESVQWEY
                     ANVRLILATTEDKNTSLLATFRRRIPAEITLPDYNNRSTSEKIQLLFEFLKDEAITID
                     SKIFCSIELFTDLLSKTFEGNVGELRNEIKLLCAEGYLGNKRKSSIYLGDKLDSGFWI
                     DPEISIDLKKMFLKSLSEIDLIELFQNHISIEESMSQLRDRILKECAGSSEYNYLESD
                     EFIALRNYVVNKISPIIDSTGLCLLDEFLADISLFIMFIDVIEETSRNFLLSKFRKFR
                     MKNDKQKLLANEIWSSLEVEESKQELLLKWILFLVKKFYVKIPETHCLIVMHGKITAS
                     AIARETNKLLNTYVYEAFDMPIEGETSDLINLINNFCKSIDTTNGLILLVDMGSLEQM
                     YEKIESNVIGDLVILNNVSTALAIECGIQVCQKKPISHFYQMDFDSFQVKVQYYKGLS
                     QKKNVIVSCLSGEGISEKVKDILKRYLDNQVEILIFDFNALKKIAKEKDTMIFKNTIC
                     VLSTTEFYIQGIDCLNLENLINGNQTLEKLNKYMDSDSCEFCLNELVKLFTIEGASTK
                     LRFLDSKKVFNEIEKVLYLYEKYYDVKIPSFLRINLFLHLSGMIERIMIGDGITNEHL
                     KEGAQLFDTFLNVSKDFFSEIKDIYCIEIPKGEYELIYTIFEQTIF"
     gene            10538..11311
                     /locus_tag="J8S10_002278"
     CDS             10538..11311
                     /locus_tag="J8S10_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAZ9630856.1"
                     /translation="MAFWQTFLVVLYGFFINWDKEGPKIGTSQPVVAGFLTGLIMGDI
                     QTGLYIGGTLQLMTLGITSFGGASVPDYQTAALIGTYLAISTNQDASIGITLAIPVAM
                     LIVQLDVLKWSTNIFFQQKAEKFAQKEDYQKLEWMQYLASINTSFVSGIPVLLTVILG
                     PTLVGSAINYIPEWVTGGLKVAGGLLPAVGIGMLLKYLPTKDYFAYLLVGFVLAVYFQ
                     IPILGISLLGAAIALIVYKNRSNNTQVAPAATGGFDEDE"
     gene            11304..12095
                     /locus_tag="J8S10_002279"
     CDS             11304..12095
                     /locus_tag="J8S10_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAZ9630857.1"
                     /translation="MNKKLTKIDKQVIFRWILNGATSLNYEKMEGLGYAYSMLPFIKD
                     TYKDDPEGMKQSVLAHLQFFNTTPYTAPYIIGMNVGIEKEEKNKSLEAVSALKTGLMG
                     PLAGIGDSVFVVIPWTIFGAIAANMALEGSFVGIILWILASILLRITAYPLYLAGKES
                     GASLLTQIETKLKSITDAVSILGLMVVGALIATVVKVNVGFEFKQGDLTMTGNEIFDQ
                     VMPGLLPACVVAIVYYLLGRKVKPVYVILLILVVSIALRALNILK"
     gene            12105..12596
                     /locus_tag="J8S10_002280"
     CDS             12105..12596
                     /locus_tag="J8S10_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAZ9630858.1"
                     /translation="MDEKMKGIIHVRIDDRMIHGQVATQWTNQLSANRIMVINNEVAN
                     DDVKKAVVRLAAPPNVRTSIITREVAVKNILSGKYEGQKVLIVAVSPIDVKFLIDNGL
                     PITSVNVGNLSRRNGTERIRPTINITEEEREAFKELISDGVEVTVIQTPRDSKEFLKD
                     FIY"
     gene            12614..13024
                     /locus_tag="J8S10_002281"
     CDS             12614..13024
                     /locus_tag="J8S10_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAZ9630859.1"
                     /translation="MEFIITSHGNIAIGFVDTLKMFFGDNLNCHVVTLGDAGIEEFRE
                     NIEKIVSQVKNQEVMVFADLIGGTPFNEFAKRSEVFQNGFQLLGGMNLGILIEAVNLR
                     LQGKKSDDIIENLRNMNTIACLADMQRHTNEEDE"
     gene            13028..14428
                     /locus_tag="J8S10_002282"
     CDS             13028..14428
                     /locus_tag="J8S10_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-fructofuranosidase"
                     /protein_id="HAZ9630860.1"
                     /translation="MQKIFYKPKDFWFGDCMPFYKDGTFYLFHQRDTRNPKPLTDPFG
                     WSLVTTTDFVKFEEYGEVIHRGGNDDIDQYIYAGSIVQGINEYLALYTGHNRKAKLDG
                     KTSEVLMIASSKDLIHWKKDGEAAKLVPQEGYDKNDWRDPFAIFDQDHGKYVLILGAR
                     KPASKKKPTGRLVYFESEDLKDWNFKGDYWANNEFNMIEMPDIFEIDGTWYLLFSEYC
                     EDKKTKYRVGAGLFSDWKSPVDEAFDGKAYYAARTVGTNETGRFLTGWVATKEGENDQ
                     NNWDWGGALVPHQIIQKTDKTLGVKLPEKIIENFKEITPFSSFKLEKEFGKKERVIVP
                     KIEDYFLFETTLTITSLTKEFALKLFVDSDTQEGYEFRISLINNQLTFGKTPNYPWPQ
                     MFDKGLQRPLFLEIGKEYELKLIVDDTIAVLYIDNVALSTRMYDKVGTALSMTVTEGA
                     IKVDKLDYSINYECGF"
     gene            14451..14825
                     /locus_tag="J8S10_002283"
     CDS             14451..14825
                     /locus_tag="J8S10_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HAZ9630861.1"
                     /translation="MKLNGLQHIGIPTKDFGASKIFYESLGFSLINEEMNVGSKVGFF
                     ELNGTIIEIWEDKTTECRGAIDHLALDTDDIDEVFNSIQDLGYELLDKNIMELPFWEN
                     GIRYFNFYGPNHEIIEISQMKK"
BASE COUNT         5287 a         2134 c         3045 g         4763 t
ORIGIN      
        1 ttttttattt gtctcgctta attatacaaa cggcgtgata aaaaacgaga aatgaattat
       61 aggtttagac ctttatcatt tctcgtttta ttttattgta tcaaggctct atcataagtg
      121 gtaaaatcta cttttaaatc acatgtaatc attgataagt ccagtgtttt agcggataat
      181 cagcttttta tttatttttt cttataaatt tgataaatag aaattagtat agccctaaac
      241 aaattatttg tgttttattg tttagggcta tactatattg gtacaaggaa tagaaagagg
      301 tgtttatgtg gttgataaaa ttcagtttaa tcaagttata gaagaattca tcaaagtaaa
      361 taatttaatg acccatattc aaaaacgacc aatcagaata actaatgatc taaaactcag
      421 tacgagtatg attcatttga ttgatgtgat tggaaattat cctgaaacta gtattacgga
      481 attagctgat cgattaggcg ttaccaaagg agctgtatcc caacagattc ccactttaga
      541 gaaaatgaat cttataagca tttctcaaaa aaaaggaaat aagaaaacta aacttgtatc
      601 gttaacaaaa tatggtcgaa aggtgtacga atcacataat tatttacatg aagagcttta
      661 tagctcaata aatgaagcgt tagaatcatt ctcaccagac caaatttcaa ccattaaaca
      721 gattctagaa aaagtatctt atacaatcaa tgaatatcaa gtaagtctga caagaaagga
      781 agattgacat gaaaaaaatg atttttgaat cggctacact agactagaca gaaaaaataa
      841 ggtgtgtaaa ataaatgaaa acacactgga ggaattttta tgtcaagacg tcaacgtaga
      901 acctattcaa aagaattcaa acaacaagtc gtcgatcttt atctcgcagg aaagccccga
      961 gctgaaatca ttcgagatta tgagctgact acctcggcct ttgataagtg ggtcaagcaa
     1021 gcgcaaacta ctggctcgtt tcaggaaaaa gataacttga tccctgaaca agtagaacta
     1081 attgcattac gaaagaaaaa taaacagctt gaaatggaga atgacatttt aaagcaagcg
     1141 gcgctgatat tgggacgaaa agacaagtaa ttgataccaa taagcacaaa tactcaatat
     1201 cagcgatgtg taaagtgtta aacatctctt gccaaaccta ttattatcaa gccaaaccag
     1261 ttgaagatga atcagaactg gaagaactcg ttcaagaaga atttattcgc aatcgaaaag
     1321 cttatggtac caggaagctg aagcagtgct tggccaatct aggtcttcaa gtgagtcaac
     1381 gcagaatcgg ccgtatgatg aaacagcgtg gcttgcgttc aacatacaca ttggctcatt
     1441 tcaaattcca ttcttctact tgtaacgaag ccaagaccgc caatattcta gacggaacct
     1501 tcctacagga aaagtcatta gaagcgattg taaccgacct tacctatgtt cgtgttggga
     1561 agaaatggca gtatatctgc ctgattcttg atttgtttaa tcgagaaatc atcggctatt
     1621 catgcgggga gaagaaagat gcgacgttag tcaaggaagc ttttgcaaag attccgtact
     1681 cgttgaataa tgtacaactt tttcacacgg atcgtggaaa agaattcgat aaccagacga
     1741 ttgacgaaat tttatgggcc tttaatatca cgcgttcctt aagcaaaaaa ggctgcccct
     1801 atgataacgc cgttgcagaa tccacctata aatctgtcaa agtagaattc gttcatcaat
     1861 accgctttga gacattggct aatttgcgat tagagctatt tgattacgtc cattggtgga
     1921 ataccatccg gctgcacggc acgttaggct atgagacacc gatcagtttt cgacagcaga
     1981 gattggcgca gcgaatcctt gataatgagc tcggatgtga taccggtggc gaggcacctt
     2041 aattatttga atgagcttct gccttagaga atcagattcg aggaggctcg ttgtcaaggg
     2101 cagtcggaac accagcagca agcttacgca ataccttata atttttgtca aaaaaagtgt
     2161 tgccattcca catatatctt taaacagcta ttgccagata aaaataaatg atattatata
     2221 tataaatact tatccgaaaa ggggaatgag agagtcaagg ttcttggaat gtcgaatagt
     2281 cgagtaggta gattttctat ctacaacctt gttgtttaaa aatgaaaaaa attggaatta
     2341 gagaagttgc gaaagaggca aatgtttctc ctacgactgt gtcgagggta ttgaatgatc
     2401 gtggatattt gagtgaggaa acaaaaagaa aagtttttga tgccatgaaa aaattagaat
     2461 actatcctaa tgaactggcg agagcacttt ttaaaaacga aacatatacc gtaggtttga
     2521 tttttcctac aattactaat ccatttcacg ctgagttaat tcaagatatc gagttcgagc
     2581 tttccagcag gggatataaa gtgttgctgt gcaatagctt aaacaatcca acaaaagaaa
     2641 aagagtactt gacgatgttg agaaagaatc aggttgatgg aattatagta ggaacgcaca
     2701 ataaagatat tgcggattat gatattccag ggctacctat tgtagcgatt gatagaagtc
     2761 ttggtgaaaa tacagttaca gtatcttgtg ataattacag gggtggggaa ttagctactc
     2821 aactacttgt aaatcatggc tgtcagaata tactgtgtat tcggggagat agtaagataa
     2881 agctacccgc gaatagtagg actttagcat ataaagatgt tttgaataaa ttcatgctgg
     2941 aaccgttagt cctagaagta ccatttgtaa aagaaatcaa tgaaaaaaat gaaataatta
     3001 agacatatct ggaaactcat ccaaatattg acggggtttt tgcaggagat gatttattgg
     3061 cttctttggc gattaacaac ttaggaagtt cgggcaaaag agttccaaaa gaggttaaag
     3121 tgattggatt tgatggagct caacaaacat tgatttataa tccagaatta tcaactattc
     3181 aacagcctat agatcaaata tctaaagtag cagtaaaaaa attattgaat atgattaagg
     3241 gcgaaaagga gacggatgaa ctttcacttc cagtaaagct cataaaaaaa aatacagcat
     3301 aagttaaatc ggcgaaaaat tccttcgtcg atttaaaaat atttttatga aacgggttga
     3361 catatgaaac gggttgacat atattagttg tgaagataaa aaccttttca ctggaggaag
     3421 aaaatggaga aattattaat taaaagcaat aatcatcaac tttactacca acctaaggat
     3481 gtttgggtcg gagatgttat gccttacggg aaagaaggaa aattctttat ttatcatcaa
     3541 cgtgatacta gaaatccagt tccttttgga gaaccgtttg gctgggcttt agcaactacg
     3601 aaagattttg ttcattttga agactttggg gaatctcttt taagagggga tgacaatgag
     3661 agagaccagt ttatctacgc tggttctgta tttgaggcaa atggaaaggt tcacgcattt
     3721 tatacagggt ataatcgtga attcttagcg cagggaaaga catctcaagt gttgcttcat
     3781 gctgagagtg atgattttgt tcattgggaa aaatcagaaa cagcattgga gttagaacca
     3841 caagaagggt atgatattcg aaactggaga gatccatttg tcgtttggga tgatgaaaaa
     3901 gaagaatatt tgctaatttt aggggcgcga aagggtcagg ataaacatct acaaaccgga
     3961 cgtttagtgg aatttacatc aaaagattta actaattggg aattcaaagg tgatttttgg
     4021 gctccgggat tgtataccat gtttgaaatg ccagaacttt tcaagattgg tgactggtgg
     4081 tatcttgtct attcagaata ctcagatgga aataaaatac tctatcgaat gagtcaaagt
     4141 ttggaaggtc cttggattaa gcctaaagat gaagcttttg atggacgggc ttattatgca
     4201 ggtagaacag cttatgatgg aaaacgtcga gtcctatttg gatgggtacc aacaaaagat
     4261 caagaaaatg ataaaaacaa ttatttatgg ggaggtactt tggttcctca tgaagtctat
     4321 caaaaagagg atttttcact tggggtaaaa cccatagacg aagtgtggaa tgcattcata
     4381 aatttacatg atattgccga tgtagagata gaaacagcag acacaagaga agaagtaacg
     4441 cttgtcaaaa atagtggaac tttgtttaat ttagaaacaa caatttcatt tgatgagaat
     4501 cttagtgact tttcactgag attatataaa aaccttgaga cagatgaatc ttacgaatat
     4561 cgcttcaatt tagatgaggg gcgtcttaca tttgataaaa acccttgtta cccttggttt
     4621 caatatatgg ataaaggact tattagacct atatctttaa agcctaacca atcttataaa
     4681 ctaaaagtga ttgttgatga caatataatg acactttata ttgatggaat cgctcttaac
     4741 gctcgtgtac atggttgttt tggtcaagca attactatta cagcaacaaa tggatcaatg
     4801 actgcaataa ataccaagtt ttcaaatgaa ataaagaaat aataaacgtc aatcatgtgg
     4861 caggtctgaa aatcaaacat gacctgtcac atttaaaagg gaggataaat gaatggacta
     4921 caaaaaaatt gccgaagatg tattggaaaa cgttggagga aaagagaata tctcaagcgc
     4981 tacacactgc attactcgtt tacgtttaat tcttaaagac aaaagcaaag cgaatatgga
     5041 aatgcttgag gaaatagaag gtgcaaaagg tgttcttttc aatagtggac agttacaagt
     5101 aattttcgga acaggtataa ttgaaaaggt ttacaaagag ttcgttgaat tgacaggagc
     5161 taaggaagta tccgtttctg aaatgaaaga cgaaggagtc aataattcag gaaatagact
     5221 tcaacgagct tttaaagttt tctcggatat ctttattccg atcattccag cttttattgg
     5281 ggcagcaatg gttttaggaa ttcgttcgtt gattaccact cctggaatgt ttggaatgga
     5341 tggctcattc gctgatcaca atgtattcct aaatgattta tccaaatttc tgggtattat
     5401 tgcaaccaca tttgattatt taccagtttt agttatgtat tctgcaacaa aacgttttgg
     5461 cggaaaccct attttaggat tacttgtagg atttgttatg attcatccag gactagccaa
     5521 tcggaatgat ttcgtcatgg gaactataaa gcctgattat tggcatttat ttggattaag
     5581 cattccagca gttgcgtttc aagggggtgt ttttccagca attttgactt cttggttttt
     5641 agcaaaagtt gagaaaatta caaataaata ttctcctcaa gtacttgctt acattttagt
     5701 cccaactgtg acaattgttc ttgccaactt tgcactattt ttagtgtttg gtccattggg
     5761 gaattttatc ggtaatgttt taggtggaat cattgatttc ctatatatga agatgggtgc
     5821 ctttggtgct tttgtttttg caggcgcgtt acaaccatta gttgtaacag gaacacaaca
     5881 tgctattcaa ggtattgagg caaacttagt cgcaacaact ggattcaatt atatccaacc
     5941 tatttggtca gtttcaatta ttgcccaagg tggcggttgt attggtatgt atttactctt
     6001 taagaaaaaa tctaaagata gagatattgc gatttcaagc tttattccaa cactggtagg
     6061 tattactgaa ccggctatct ttgctgttaa tttgaaatat tcaatcgttc cttttgtttg
     6121 ctcgtttatt ggtgctggtt ttggtggagc atttatgaaa atttttgatg taaaagccat
     6181 tggacaagga ttgactgtat tgccaggtct gactattgct aatccagttc ttccttatat
     6241 atttggtaat ctcatagcat tcattttacc aatcattttt attctcgctt atgataaata
     6301 taaagtgttt atccctgaag ctaaacaccg taaatttgca gaaaaaactg actcaaaaaa
     6361 attgccagtt caagtaaagt gagatgagag catgttaaat ttttttagaa aaaatgaaat
     6421 aagcgttgta gcacctgcaa ccggtgtttt tgaaaaactg gagaaattaa gtgatccagt
     6481 cttttcaaaa ggaatgatgg gacaaggatt tgcaattgat gcaaaaaacg aaacgattgt
     6541 atctccaatc gatggttttg tttcaagtat ttttcctaca aaacatgcct taggaataaa
     6601 aacaaaatca ggaattgaga tacttgttca tgtaggaata gatacagttg agctaaatgg
     6661 tgagggattt gatattaaag ttcaagaagg acaaaaagtt aaggctgggg atattcttat
     6721 gaccattaat tttgtagttt ttgaaaagaa tcacaagact aaagatgtca ttgttgtttt
     6781 tccagactac caagacgaaa ttttcattcc gaaacttgaa gaagtaaaac aaggacaaga
     6841 attgtttgtt cttggctaat gataagtaat taataataga atcgaggaaa atgtatggtt
     6901 tttggggcta ttgaagctgg tggaacaaaa tttgtttgtg ccattggaga taaagatttg
     6961 aacatatttg aaaaagtcag ctttcccacg actacaccca aagaaacaat gaatttagtt
     7021 ttagattttt ttaatcatca taaagatgat ttagaaggta tcggagtggg atcgttcggt
     7081 cctattgata ttcattgtga atctaaaacg tatggcttca ttaaatcaac gccaaaactt
     7141 gcttggcagg attttgattt tattggaagt ttaaaaaagc aacttaatat tccaactgct
     7201 tggacgactg atgtaaatgc ctcttgctat ggtgaatatg tttctggaaa tggcagaggc
     7261 ctttcaagtg ttgtttacta taccgtagga acgggcatag gaggtggcgc tatccaaaac
     7321 ggaaacttca ttgaaggttt tagtcatcca gaaatgggac atatgcttgt aaaacgacac
     7381 aataaagaca acttttctgg gacatgtcca ttccacggag actgtttaga gggcttagct
     7441 gctggtccgg caatcgaaag aagatcaggg aaaaagggac aagaagtgac tgaaaatgac
     7501 gttacttggg aaatagaagc ttattacatt gctcagtgtg catataatac aacattgatg
     7561 ttatcacctg atgtcattat atttggtggc ggagtaatga aacaaaaaca cttaaaaaag
     7621 aaagtacaag ataagtttat tgagttgatc aacggatatg tcgctattcc cgatgttgac
     7681 aattatatta tgacaccaaa attgttagat aattctggta ttgtaggttg tttagcttta
     7741 gcaagagacg ttaaagaaaa atcttaattt ggaaaaaaga tcgtctcgac tatttgtttg
     7801 gttgatgcga tctttttttc aattagtaat tgaagggacg cctaaaagtg aaaaaaaaaa
     7861 tgaaagatga agtattagag tatatcaaaa ataatttaaa gtattacgat ttttctgctc
     7921 aagatattgc aatgaaattt tgtattaaaa gaaatgtcgc ttcccactat ttgaatcagt
     7981 tattttcaga tggaaaatta ctaaagaatg attctgttag accagtaatg ttcaagtata
     8041 atcaacaaaa gccaaaagac tgcttttcta agtttattgg agcagacata tctttgaaat
     8101 ccactataga taaatgcaaa gctactgtaa tgtatccccc taatggcctc ccattaataa
     8161 taaaaggaaa cagtggcgtt ggaaaaagtt ttttagcaag tttgatctat cagtatgctc
     8221 ttgatagaaa agtaattcat aatgacgcaa aatttgttgt tgtgaattgt gcagattatg
     8281 caaataatcc agagctattg tcagcagttt tatttggata taaaaaagga gcctttactg
     8341 gggctgaaaa agatactgca gggatgctat cttctgctaa tggaggatac ctttttttag
     8401 atgaggttca caatctaagt gcagaaaacc aagagaaatt gtttcttctt atggattctc
     8461 aaaagtatcg taaacttggt gaaagtgtgc aatgggagta tgcaaatgtt cgccttatct
     8521 tagccacaac agaagataaa aatacctctt tgttagcaac ttttagaaga cgcatcccag
     8581 ctgaaatcac tctgccagat tacaataata gaagtacatc tgaaaaaatt caattattat
     8641 ttgaatttct taaagatgaa gcaattacga ttgattcaaa aatattttgt tcgattgaac
     8701 tttttactga tcttttatcg aaaacatttg aaggaaatgt tggagaattg aggaatgaaa
     8761 tcaagcttct ttgtgcagaa ggttatttag gaaataagag aaagtcttca atttatttag
     8821 gggacaaact agacagcggt ttttggatag atccagaaat tagtatagat ttaaaaaaaa
     8881 tgtttcttaa atcactttct gaaattgatt tgattgaact ttttcaaaat cacatttcaa
     8941 ttgaagaaag catgagtcaa ttaagagata gaatacttaa agagtgtgca ggttcttctg
     9001 agtataatta tttagaaagt gacgaattta tagcattaag aaactatgtt gttaataaaa
     9061 tatcaccaat tattgattcg acaggtctat gtttattaga tgaattcttg gcggatatca
     9121 gtctatttat aatgtttatt gatgtaattg aagaaacatc aagaaatttt ttgctgtcta
     9181 agttcagaaa atttcgtatg aaaaatgata aacaaaaatt attggcaaat gagatttgga
     9241 gtagtttaga agtcgaagaa agtaaacaag aacttttgtt gaaatggata ctttttcttg
     9301 taaagaagtt ctatgtgaaa ataccagaaa cccattgtct gatagttatg cacggtaaaa
     9361 taacagcttc tgcgatcgca agggaaacaa ataagttgct gaatacatat gtttatgagg
     9421 ctttcgatat gccaattgaa ggtgagacta gtgacttaat taacctaatc aacaattttt
     9481 gtaaaagtat agatacgacg aatggactca ttctgctagt tgatatggga tcattggaac
     9541 aaatgtatga aaaaattgaa tccaatgtaa taggtgattt ggtaatttta aacaatgttt
     9601 ctacagcttt agcgattgaa tgtgggattc aagtttgcca aaaaaagcca attagtcatt
     9661 tttaccagat ggattttgat tcgtttcaag ttaaagttca gtattataaa ggattatcac
     9721 aaaagaaaaa tgtaatagta tcttgtctct ctggtgaggg gatttctgaa aaagttaagg
     9781 atattttaaa acggtatctc gataatcaag tggagatttt gatttttgat tttaacgcat
     9841 taaagaaaat agcaaaggaa aaagatacta tgatttttaa gaatacaatt tgtgttcttt
     9901 caaccactga attttacatt caaggaatcg attgtttaaa tttagaaaat ctaattaatg
     9961 ggaatcaaac cttagaaaaa ttaaataagt atatggactc ggatagctgt gagttctgct
    10021 taaatgaatt agttaaactc tttactattg aaggcgctag tactaagctt cgctttttag
    10081 attccaaaaa agtattcaat gagatagaaa aagtactata tttgtatgaa aaatattacg
    10141 atgtcaaaat cccaagtttt ctgagaatta atctatttct acatctttct ggaatgattg
    10201 aacgaattat gattggtgat ggaataacaa atgaacattt gaaagaggga gcgcaactat
    10261 ttgatacttt tttaaatgta tcaaaagatt ttttttcaga aatcaaagat atttactgta
    10321 ttgaaatacc caaaggagag tatgagttaa tctatacaat ttttgagcag actattttct
    10381 aaatagcata ctagcgtcta aaaaaatgaa agggtgtcca aagtatattt agacgctcat
    10441 ttaattaata tttactgtat tttcccgctt tattggataa tgttagttgg cacagtaatt
    10501 gcttatataa aagtataaga agaaaggaga gaacaaaatg gcgttttggc aaacattttt
    10561 agttgtgttg tatggatttt tcattaactg ggataaggaa gggcccaaaa tcggaacctc
    10621 ccaacctgtc gttgcaggtt tcttgaccgg acttattatg ggagatattc aaactggact
    10681 ttatatcggt gggactttgc aattaatgac actaggtatt actagttttg gtggtgcatc
    10741 agtaccggat tatcaaacag cagcattgat cggtacttat ttagcaatct caactaacca
    10801 ggatgcttct ataggaataa ctttagcaat accggtagca atgttaattg tacaactaga
    10861 tgttctaaag tggtcaacaa acattttttt tcaacaaaag gcagaaaaat tcgcacaaaa
    10921 agaagattat caaaaattag agtggatgca atatttggca tcaattaata caagctttgt
    10981 atctggaatt cctgttttgt taactgtgat attaggccca acgttagtgg gaagtgcaat
    11041 caattatatt cctgaatggg ttaccggtgg tttaaaggta gcagggggac tattacctgc
    11101 tgttgggata ggaatgctac ttaaatattt acctacaaaa gattactttg cctatttgtt
    11161 agttggtttc gttttggcag tttatttcca aataccaatt ttagggattt cgttacttgg
    11221 cgctgcaatc gcactaatcg tatataaaaa tagatcaaat aatactcaag tagcaccagc
    11281 tgcaacagga ggttttgacg aagatgaata agaaactgac aaaaatcgac aaacaagtaa
    11341 ttttccggtg gattctcaat ggtgcaactt cattaaatta tgaaaaaatg gaagggttgg
    11401 gttatgcgta ttctatgctt ccttttatca aggacacata taaagatgat cctgaaggaa
    11461 tgaaacaatc cgttttagct cacttacaat tttttaacac tacgccgtat acagcgcctt
    11521 acattattgg tatgaatgtt ggaattgaaa aagaagaaaa aaataagtct ttggaagcag
    11581 taagtgctct gaaaacaggt ctaatgggtc ctttagcggg aattggagat agtgtatttg
    11641 tagttattcc atggactatt tttggagcaa ttgcagctaa tatggcattg gaaggtagtt
    11701 ttgttggaat tattttgtgg atactggcat caattttatt aaggattact gcttatcctt
    11761 tataccttgc tgggaaagaa tcgggtgcga gcctactaac tcaaattgaa acaaaattaa
    11821 agtctattac tgatgcagta tcaattttag ggttaatggt ggtcggtgca ctcattgcca
    11881 cagttgtaaa agtgaatgtt ggctttgaat ttaaacaagg cgacttaaca atgaccggaa
    11941 atgaaatctt tgatcaagtt atgcctggtt tattacctgc atgtgtagta gcaattgtgt
    12001 attatttgtt aggacgaaag gttaaaccag tttatgtaat tctattaatc ttagtagttt
    12061 ctattgcgtt aagagcgtta aatattttga agtaggtgtt gaatatggat gaaaaaatga
    12121 aaggtattat acatgttcgt attgatgatc gaatgattca tggacaagta gcaacacaat
    12181 ggacaaatca attgagtgct aacagaatta tggttattaa taatgaagta gccaatgatg
    12241 acgtaaaaaa agctgtagtt cgcctcgctg caccacctaa tgttagaact tcaataatta
    12301 caagggaagt agcagttaaa aatattcttt ctggtaaata tgaaggacaa aaagttctta
    12361 ttgttgcagt ttctccaatc gatgttaaat ttttgattga taacggttta ccaataacaa
    12421 gtgtaaacgt aggaaattta tcaagaagga atggaacaga acgcatccgt ccgacgataa
    12481 atattactga agaagagaga gaggctttta aagaactaat tagtgatgga gttgaagtga
    12541 cagtgataca aactcctaga gattcaaaag aatttttaaa ggattttatt tattaagaac
    12601 agaggatgag tggatggagt ttataattac atctcatgga aatattgcca ttggatttgt
    12661 agatacatta aaaatgtttt ttggcgataa tttaaattgt catgtggtaa cacttggaga
    12721 tgcaggcatt gaagaattcc gtgaaaacat tgaaaaaata gtttctcaag taaaaaatca
    12781 agaagttatg gtatttgctg acttgattgg tggaacacct ttcaacgaat ttgctaaaag
    12841 aagtgaagta tttcaaaatg ggtttcaact tcttggtggc atgaatttag gaattttgat
    12901 tgaggctgtc aatttgagat tacaaggaaa aaaaagcgat gatatcatcg aaaatctaag
    12961 aaatatgaat acaattgcgt gtcttgcaga tatgcaaaga catactaacg aagaggatga
    13021 gtgataaatg caaaaaattt tttacaagcc taaagatttt tggtttgggg attgcatgcc
    13081 tttttataaa gatggaactt tttatctatt tcatcaacga gatacgagaa atcctaaacc
    13141 tttaactgat ccttttgggt ggtcactagt tacaaccact gattttgtga aatttgaaga
    13201 atacggggaa gtaattcatc gtggtggcaa cgatgacatt gatcaataca tttacgctgg
    13261 aagtattgtc caaggaatca atgagtattt agctttgtat actggacata atcgcaaagc
    13321 taagttggat ggaaaaactt cagaagtgtt aatgattgca agttctaaag atttaattca
    13381 ttggaaaaag gatggcgaag cagcaaaact tgttcctcaa gaaggatatg ataagaatga
    13441 ttggcgcgat ccttttgcaa tttttgatca agatcatgga aaatacgttt tgatactagg
    13501 agctagaaaa ccagcaagta agaaaaagcc gacggggaga ttggtctatt ttgaatccga
    13561 agatttaaaa gattggaatt tcaaaggaga ctactgggct aataatgaat ttaacatgat
    13621 tgaaatgcct gatatatttg aaattgatgg aacgtggtat ttactttttt cagagtattg
    13681 tgaagataaa aagactaaat atcgagtcgg agcaggatta ttttcagatt ggaaatcacc
    13741 agtagacgaa gctttcgacg gaaaagccta ttatgcagca agaacagtcg gaactaatga
    13801 aactggccgt tttctaactg gctgggtggc aacaaaagaa ggggagaacg atcaaaataa
    13861 ctgggattgg ggcggtgcac ttgttccaca tcaaattatt caaaagacag acaaaactct
    13921 tggtgttaaa ctgcctgaaa aaataattga gaattttaaa gaaatcactc cattttcaag
    13981 ttttaagtta gagaaagaat ttggaaaaaa agaaagagta attgttccta aaatcgaaga
    14041 ttattttcta tttgaaacaa ctttgactat tacatcgtta acaaaggagt ttgctttaaa
    14101 attatttgta gatagtgata ctcaagaagg atacgaattt cgtatttcat tgattaataa
    14161 tcagcttact ttcggaaaaa ctccgaacta tccttggcct caaatgtttg ataaggggct
    14221 gcaacgacca ctatttttgg aaataggcaa agaatatgaa ctaaagttaa ttgttgatga
    14281 tacgatagct gttttatata ttgataatgt tgctttaagt actagaatgt atgataaagt
    14341 cggaacagca ttaagtatga ctgttacgga gggagcaatc aaggtagata aactagacta
    14401 ttcaataaat tatgaatgtg gattttaaaa caattgaagg gatgatgtaa gtgaaattaa
    14461 atggtttaca acatattgga attccaacaa aagattttgg agcttcaaaa atcttttatg
    14521 aatccttagg gtttagtctg attaatgaag aaatgaatgt gggaagtaaa gtcggctttt
    14581 tcgagttgaa tggaacgata atagaaatat gggaagataa aactactgag tgtagaggag
    14641 ccattgatca tctagcatta gatacggatg acatagatga ggtattcaat tcaattcaag
    14701 atttaggata tgaattatta gataaaaata ttatggaatt accgttctgg gaaaatggaa
    14761 tccgttactt taatttctac ggaccaaatc atgagattat agagataagc caaatgaaga
    14821 aataaataga taacgaagtg ctctaagttg gtatgaacga aaagtacttc attttttggt
    14881 atcagcattt caatagttta atgagaattt actatttcaa attaattcaa agtgacagta
    14941 ttttttactt atttggtttc aaattttgta atccttccta tttattggaa tacactccac
    15001 attttgtata caagtcatat catgttttag caaagctctt accaagcaaa gttataatga
    15061 tgttttccaa agtttgatct ttcgatggag gctaacacat attttttgca ggacagccaa
    15121 aattagatgt atagaataga gtctgtgagg cgtatagaca gtttattgtc tgtatgcctt
    15181 tttttatttt gaaaaatttt tagtattttt cgaaaaatgc tcactccta
//
LOCUS       DADQDV010000067        15216 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.069, whole genome shotgun sequence.
ACCESSION   DADQDV010000067 DADQDV010000000
VERSION     DADQDV010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15216)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15216)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15216
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.069"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            133..636
                     /locus_tag="J8S10_002284"
     CDS             133..636
                     /locus_tag="J8S10_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HAZ9630862.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKEQIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCNLAEELEGTPIGEAASEIQHAFFNSFEEMVEH
                     VDDIVYYPDCDDMSDVAHYLIVEAGDFGEVPEQLKPYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPE"
     gene            763..1800
                     /locus_tag="J8S10_002285"
     CDS             763..1800
                     /locus_tag="J8S10_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630863.1"
                     /translation="MANIQTSFIDFHNSIRLDVEDNTLLKDYKDQVIDGLKDYLPDDV
                     KFETFLQGSYSVYTGIKSCDEKIDFDIDIAVAFEIDHTVYEDPREPKLWVKEALVEIF
                     PNAQVNLKVPCVTATFTGKKTKKNVHVDVAVYAKEDENYFLAKAKEFSAPENRCWEEA
                     DPKVLKEKINSHVADSDDRKQFRRCIRYLKRWKDNNFNQEYKPTGIGLTINVMDTFLV
                     NKSTDFLTRKVQYNDMECMKQIVSSLKDSFVYEYSETDGWHYRLHAYLPVKPNSDTYS
                     KMTVNQMSDFKNKLSKLYDDLIFAIDTEDEYEATKRLNNQFGEDFLIISEEEVTEKNL
                     RNAFVTDYPSA"
     gene            1815..3512
                     /locus_tag="J8S10_002286"
     CDS             1815..3512
                     /locus_tag="J8S10_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine biosynthesis protein ThiF"
                     /protein_id="HAZ9630864.1"
                     /translation="MDYTDILKEKLTDVVRLFDGNYYGDFSFATIGKLRLKIEIPKHF
                     PLVLPRIYIHNFDHLGLYLPHVEKDGLVCFSSDINYLVDEENSELVLLQCVNKTIKTI
                     EEGLKGLNKNDFRKEFVAFWDKQENQISLFYLCEPALFIKSVDTIMYGKSLVALDKEN
                     ELQLNAASRLFNGEKEDTHELDAYYVPIRNKNNIMPPKNNKAWSKKDILQIVKKNVTG
                     ANKRFFLKLEKRKNRHNVLLILDIPIEEKSNNVIIGFLFTKQSGSIKDYKGTPRTVLV
                     QRHDELYLVNRTSGENYGLGANIAIVGVGSVGSKIAENLGPLGVRKMTLIDNDCFQAE
                     NLYRNSLGADSLKNARSQNNFFKVDLMQEELEKKIPYLCVEVESMNVLDLISMQPGFF
                     KEYDYVFVCIGDTMASLALNNYFSKSSQKVFYSWLEPYGIGGHTLFINYSLNQKGCFN
                     CLYTDSNSKNRCSNRASLVKEGQIFERTLASCRSKFIPYNAIASTECAINAIKLFHKV
                     NQNNMTNSTLFSWIGDGSTFENLGYQYSDRNTFLNGVNKFEERFFSKYCKVCGELDD"
     gene            3505..3966
                     /locus_tag="J8S10_002287"
     CDS             3505..3966
                     /locus_tag="J8S10_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630865.1"
                     /translation="MIKFSCDRIVIEVRDEVLKIFEQYRQGKDDLPEAGGVLHGKRLK
                     NGSIIITDITTPQIGDIQKRLLFKKNREIHQQLSNEKWIESNKFSIALGEWHTHPEAV
                     PTPSNVDKKSWRLNVSKQHDDRVYVFIIVGFSDLRMWLLSKKSDIRQAIKL"
     gene            3979..4839
                     /locus_tag="J8S10_002288"
     CDS             3979..4839
                     /locus_tag="J8S10_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630866.1"
                     /translation="MKSQKNIWWWGFLVGKVMIPALLLISLPMITFFFTNKKMSKEAV
                     IFFFGDQKATFIETLVTSLQLNLNYIFSIIIVISLLNFFKKRNSGKVFNSNGNVYYNY
                     FYFVFWVAATLLGYDKIQIAGIPIHMQYKLVLSGIFSEVLPDIYDDHYDSDGTCKVSI
                     EKENFDDIDGYDSVNLLIIDTYDIKMSELSMENQTYPTIIVRGNSIDGVRKVNRSLIL
                     EIKKTMDEIQKSDFKKVFVASTSNPKNSINIINSSFRFFGRSRRFKLYVLQKDYASNG
                     KYSKKYRIFI"
     gene            4877..5266
                     /locus_tag="J8S10_002289"
     CDS             4877..5266
                     /locus_tag="J8S10_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAZ9630867.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLMFV
                     IVFAHVPPLSMIEGAFLKYLGIPIAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            5253..7700
                     /locus_tag="J8S10_002290"
     CDS             5253..7700
                     /locus_tag="J8S10_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAZ9630868.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELVPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLKEVAKQRIDLQTDALVSMI
                     GDSQIDYRFFIGFKLISTDEEVNLKNLRKSFFSGLQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVKRVTPSDLTYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPTRCLIEEKPRYLRMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAKSVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HKEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALASAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPENQGLLDPYVIMKKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSDQRGLLQVIVELRKEDSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDKEDESNQKCMRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            7705..9813
                     /locus_tag="J8S10_002291"
     CDS             7705..9813
                     /locus_tag="J8S10_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAZ9630869.1"
                     /translation="MKKKLFRIFGIVLISLVTLIILLSLVGTVAEATGLVDDTVGAGN
                     LYSQYSLGNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEVGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMNMFNLQSNDSQSMGRRVMRKPQMLMNRTLR
                     QLNRNVGRTLAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEIPSDLNKEK
                     PIPNNKKQSRMNLAGRKVGKVLDTQALVKDKTKQVKDGVRNTPTNLKYNFHKGIEKTK
                     KAPEEFKRGLVQEKANRGELREKQQQRRDEKIAEKRKVLNEIGNPHGKRRENVPIKAK
                     VQSQKDRAPKRIVRANSNPEIKRKFASQEIISKGINQSSSKKNSFQQVKRRSTLSKRT
                     NRKVQKSLNPHPKPRSGEKK"
     gene            9810..10814
                     /locus_tag="J8S10_002292"
     CDS             9810..10814
                     /locus_tag="J8S10_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase P60"
                     /protein_id="HAZ9630870.1"
                     /translation="MNVKKLSAISLTFLTISFMGILMCVGLLFGEDSEGSSSSGAPPG
                     GSSVSEEVLKHRAMVEKYAKESDITEYVPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNFGGGYLDYVAKNGKKHSFALA
                     ESFSKEKSCGQKIDYPNPIANKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGSRPETGFDCSGLTQWCYAKVGLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTESYWQQHLIGAGRYK
                     "
     gene            10833..11744
                     /locus_tag="J8S10_002293"
     CDS             10833..11744
                     /locus_tag="J8S10_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAZ9630871.1"
                     /translation="MKIKIERNQKEKSLKKKKERVVSVGKHRKMVLALWLLLSCSLTF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGIENFTKDFSKEYFSWKNNKEAIEKRMNNL
                     EQYLTEEGFALSQDMVRADIPTNSEVQSVKVLDVEKSSEEFVVSFLVEQKITEGKKAQ
                     SISSAYRVTIFEDENRNYIVTSLPTMIAKPDRAKYKTKQVENDSKIDAKTTEEIAEFL
                     ETFFKLYPSASEKELEYYVENDAMRPINIDLKFSKLEDPVYLQNGKKILVSTKIKYLD
                     NVSKTTSYFQYKLILQKNGNWKIIDVK"
     gene            11931..12218
                     /locus_tag="J8S10_002294"
                     /pseudo
     CDS             11931..12218
                     /locus_tag="J8S10_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(12406..12621)
                     /locus_tag="J8S10_002295"
     CDS             complement(12406..12621)
                     /locus_tag="J8S10_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630872.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(12880..13047)
                     /locus_tag="J8S10_002296"
     CDS             complement(12880..13047)
                     /locus_tag="J8S10_002296"
                     /inference="COORDINATES: protein motif:HMM:NF018933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAZ9630873.1"
                     /translation="MGSECGHTDGKKSFTIREWTCPICRTHHDRNVNVSINILIKGYV
                     YKHCLRKHQEP"
     gene            complement(13392..14831)
                     /locus_tag="J8S10_002297"
                     /pseudo
     CDS             complement(13392..14831)
                     /locus_tag="J8S10_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172772.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
BASE COUNT         5053 a         2492 c         3089 g         4582 t
ORIGIN      
        1 gagttttcca aactgattgg cttcttggtg attgctttga ttgcggtagg tctggtcttt
       61 aatgcttctg gtgtgaagga tgtcctactc aatttgttta accgaattgt cggtgcctga
      121 gggggaatca caatggaaca gatgcgtgtt tatattgcga accttggaaa atacaatgaa
      181 ggtgagttgg tgggggcatg gtttacccca cctgtcgatt ttgatgaagt gaaagaacag
      241 attggattaa atgacgaata tgaagagtac gcgattcatg attatgaact gccttttgag
      301 attgatgagt atacgccaat tgaagagatt aatcggttgt gtaacttagc ggaggaacta
      361 gaaggaacgc caattggtga agctgcttct gagattcaac acgctttctt caattctttc
      421 gaggaaatgg tagagcatgt ggatgatatt gtctattatc cagattgcga tgatatgagt
      481 gatgtggcgc attacttgat tgtagaagct ggtgattttg gcgaagttcc agaacaattg
      541 aagccgtata ttgattttga tgcttgcggt cgagatttgg agattggagg aaattatttg
      601 gttactagtc gtggagtttt tgagtatcca gaatgaatca aacactatat atagtgtttg
      661 attagtatat gtaagcaaaa aaacacaata tatagagtgc aaactgaagg gtaatgtgat
      721 ataatatttg ccgaagaaat atttttgaaa tgaggtaata ttatggcaaa tattcaaaca
      781 agttttattg atttccataa ttcaattaga ttggacgtag aagacaatac gctacttaag
      841 gactataaag accaagtaat tgatggatta aaagattact tacctgatga tgtgaagttt
      901 gaaacttttt tacagggaag ctattctgtt tataccggaa taaaaagctg tgatgaaaaa
      961 attgattttg acatcgatat tgcagttgct ttcgaaattg atcatactgt ttatgaagat
     1021 ccaagggagc ctaaactgtg ggtaaaagag gcgctagttg aaatttttcc taatgctcaa
     1081 gttaatttaa aagtaccttg tgtaactgct acatttactg gaaaaaagac aaaaaaaaat
     1141 gtgcacgttg atgttgcggt ttatgctaaa gaagatgaaa attatttctt agcaaaagca
     1201 aaagaattca gtgctcccga aaaccgatgc tgggaggaag cggatcccaa agtattaaaa
     1261 gagaaaatta atagtcatgt agcagattca gatgatcgaa aacaatttcg aagatgtatt
     1321 cgctatttaa aaagatggaa agataacaat tttaaccaag aatataaacc aacaggaatt
     1381 ggacttacaa ttaatgtgat ggatacgttc ctagttaata agtccactga ttttttaact
     1441 agaaaagttc agtataatga tatggaatgt atgaagcaga ttgtttcttc gctgaaagat
     1501 tcatttgtgt atgagtacag tgaaacagat ggttggcatt atcgtctaca tgcatatctt
     1561 ccagtgaagc ctaacagtga cacctattca aaaatgacag tgaatcagat gagtgatttt
     1621 aaaaacaaac tttctaaatt atatgatgat ttgattttcg ctatcgatac tgaagatgag
     1681 tatgaagcta caaaacgatt aaataatcaa tttggggagg attttttaat tatttcagaa
     1741 gaagaagtta cagaaaaaaa cttaagaaat gcatttgtta cagactatcc gagtgcttag
     1801 gttggtgtta aagattggat tatactgata ttttaaaaga aaagctaaca gatgttgtgc
     1861 gtttattcga tggtaattac tatggggatt tttcatttgc tacaattgga aagttgcgtt
     1921 taaaaattga aataccaaaa cattttccat tggtacttcc taggatttac attcataatt
     1981 ttgatcattt aggactttac ctaccacatg tagaaaaaga tgggttggta tgtttttctt
     2041 cagatataaa ttatttagta gatgaagaaa attcagaatt ggttttattg cagtgtgtta
     2101 ataaaactat aaaaacaatt gaggaaggtt tgaaagggtt aaataaaaat gattttcgaa
     2161 aagagtttgt tgctttttgg gacaaacaag agaatcaaat ttcgttattc tacctttgtg
     2221 aaccagcgtt gtttatcaag tcagttgata caataatgta cggtaagtct ttggttgctt
     2281 tggataaaga gaacgaatta caattaaatg cagcgagtag attgtttaat ggagagaaag
     2341 aagatactca tgaattagat gcatactatg ttccaattag aaacaagaat aatattatgc
     2401 ccccgaagaa taataaagca tggtcaaaga aggatatttt acaaatagta aaaaaaaatg
     2461 taacaggtgc aaataaaaga ttttttttaa aacttgaaaa aagaaagaat agacataatg
     2521 ttttacttat tctagatatc ccaattgaag aaaagtcaaa taatgtcata attggatttc
     2581 tttttacaaa acaatctgga tctataaaag attataaggg tacgcctagg actgtattag
     2641 ttcagcgtca tgatgaatta tatttggtga atagaacgag cggagaaaac tatggattgg
     2701 gtgctaatat agctattgtt ggggtagggt cagttggcag taaaattgct gaaaatcttg
     2761 gtccattagg tgtgagaaag atgacactca tagacaatga ttgttttcaa gctgaaaatt
     2821 tgtatcgaaa ttcacttggt gcagatagtt taaaaaatgc ccgatctcag aataattttt
     2881 ttaaagttga tttaatgcag gaggagctcg aaaaaaaaat cccatacctt tgtgttgaag
     2941 tggagtcaat gaacgtttta gacttaatta gtatgcaacc tggttttttc aaggaatatg
     3001 actatgtttt tgtttgcata ggagatacaa tggcaagcct ggctttaaat aattattttt
     3061 ccaaaagtag tcaaaaagtt ttctattctt ggctggagcc atatggcatt gggggacaca
     3121 ctctatttat aaattattct ctaaatcaaa aaggttgttt caattgtctt tatacagatt
     3181 caaactctaa aaataggtgt tcaaatagag cttctctggt aaaagaagga caaatttttg
     3241 aaaggacttt agcgagttgc cgctcaaaat ttataccata taatgctatt gcctcgacgg
     3301 aatgtgcaat taatgcaata aaacttttcc ataaagtcaa tcaaaataat atgaccaata
     3361 gtactctttt ttcatggata ggagatggga gtacttttga gaatttagga tatcaatata
     3421 gcgacagaaa tacttttctt aatggagtca ataagtttga agaaagattc ttttctaaat
     3481 attgcaaagt atgtggggag ttagatgatt aaattttcgt gtgaccgtat tgtcattgaa
     3541 gtaagggatg aagttcttaa gatatttgaa caatatcggc agggaaagga tgacttgcct
     3601 gaagctggag gagttcttca tggaaaaaga cttaagaatg ggagcataat aattaccgat
     3661 ataacaacac ctcaaatagg agatatacaa aaaagattac tctttaaaaa aaaccgagaa
     3721 attcatcaac agctttctaa tgagaaatgg atagaatcaa ataagttttc tattgcattg
     3781 ggagaatggc atactcatcc tgaagctgta ccaactccat caaatgttga taagaaaagc
     3841 tggagactga acgtgagcaa gcaacatgat gatagagttt atgtttttat tatcgttgga
     3901 ttttctgatt tgagaatgtg gttactgtca aaaaaatcag atattaggca ggctataaaa
     3961 ctataaagga gtgattaggt gaaatcacaa aagaatattt ggtggtgggg gtttttagta
     4021 ggaaaggtaa tgataccagc ccttctctta atttctctac cgatgattac ttttttcttt
     4081 accaataaaa aaatgagtaa agaagccgtg atttttttct ttggagacca aaaagctacc
     4141 tttattgaaa cgttagtaac atctcttcag cttaatttga attacatttt ttcaattatt
     4201 attgttatat cgttattgaa tttttttaaa aaaagaaatt caggaaaggt gtttaactct
     4261 aatggaaatg tgtactacaa ctatttttat tttgtatttt gggtagcagc aactttactt
     4321 ggttatgata aaattcagat tgcaggaatt cctatacaca tgcaatataa gttggttttg
     4381 agtggaattt tttctgaggt gttgccagat atatacgatg atcattacga cagtgatgga
     4441 acatgtaaag taagcattga aaaagaaaat ttcgatgaca tcgatggata tgactctgtg
     4501 aacttactga ttattgatac ttacgatata aaaatgagtg aattatctat ggaaaatcaa
     4561 acatatccta cgataattgt tagagggaat tcaatagatg gagttcgtaa agttaataga
     4621 tctttaatct tggaaataaa aaaaacaatg gatgaaattc aaaaaagtga ctttaaaaaa
     4681 gtatttgttg cttcaacatc taatccaaaa aatagtatca atattattaa ttcatcgttt
     4741 agatttttcg gtcgatcacg taggtttaaa ctttatgttc ttcaaaagga ttatgcaagc
     4801 aatggaaagt atagtaagaa atatagaatt tttatttaag aaggaatttt tccttctttt
     4861 tattttggag gaaactatga aaaaaataaa aagctacacc agtatttggg cagttgaaaa
     4921 agtcatttat gcgattaatg actttcagct gccttttcct gtgaccttta accagatggc
     4981 ttggtttgtt ttatccttga tgtttgtcat tgtatttgcc catgtgcctc cgctatccat
     5041 gatagagggg gcttttttaa aatacttggg cattccgata gcggtcactt ggttcatgtc
     5101 gcaaaagacc tttgacggta agaaaccatt gggattttta cgatccttta tcagctatca
     5161 cttacggttt aaggtcactt ttgcaggaaa gaaagttaaa gaacagaaga aacgatggga
     5221 cgaaccaatc accttggtaa ggagtgtgaa ttatgtaccc gattaagtat attgaaaata
     5281 atcttgtctt taaccaagaa ggcgagtgtt ttgcttacta tgaattagtg ccttacaatt
     5341 actccttttt gtcacctgaa cagaagtatc aagtacatga taactttcgc caattaattg
     5401 cgcaaaatcg tgaaggtaag atccatgcct tacaaattgc cacagaaagt agtattcgtg
     5461 ccacacaaga acgttcgaaa aaggaaatta ccggtagact caaagaagta gcaaagcaac
     5521 gaattgattt acagacagat gcattagtat ccatgattgg cgatagtcag attgattatc
     5581 gcttctttat tggctttaaa ctgatttcga cagatgaaga ggtcaatcta aagaatctca
     5641 ggaaatcttt cttttctgga cttcaagaat ttgtctatgg agtgaatcat catttgatgg
     5701 gtgattttgt ttccttatcc aatgaagaaa ttcgtcgcta taccaagctt gaaaaactaa
     5761 tggaaagtaa attggctcga agatttaaag tcaaacgagt aacgccgagt gacttgacgt
     5821 atttaattga acatatctat ggtgaaaaag gcacaccgtt tgaagaatat gaattccagc
     5881 taccaaagaa aaagctgaaa tcagaaacgc tggtgaaacg ttacgactta ttacgtccca
     5941 ctcgttgttt gattgaagaa aagcctcggt acttacggat ggaacatgaa aatcatgagt
     6001 cttatgtagc gtacttaaca attaatacca ttgtagggga aatggagttt ccttcctcgg
     6061 aacttttcta ttaccagcaa caacaattta cgtttccgat tgatacttca atgaatgtgg
     6121 aaattgtgac gaataaaaag gccctagcta ccgttcgtaa taagaaaaag gaattaaaag
     6181 atttagacaa ccatgcctat caatctgata atgaaacgaa ctccaatgta ttagatgctt
     6241 tggattccgt ggatgaattg gaaaccacct tggatcagtc gaaagaatcc atgtataaac
     6301 taagctatgt ggttcgagtg agtgctaaat cagtggatga attaaaacgc cgctgtgatg
     6361 aagtgctcga tttttatgac gataccaatg taaaactagt ccggcccttt ggcgatatga
     6421 tgggtctaca caaagaattc ttaccctcaa gtaagcgata catgaatgac tatattcaat
     6481 atgttacgtc tgactttttg gcgggacttg gttttggggc tactcaaatg ctaggagaat
     6541 tagaaggcat ttactttggc tataacgtag atacggggcg caatgtttac ctgaaaccgg
     6601 cattggcatc acaaggggtc aaaggctcag taaccaatgc tttggcatct gctttccttg
     6661 gttcgttagg tggggggaaa tcttttagca acaatctctt agtctattat gccgtccttt
     6721 ttggtgggca agctgtgatt gtcgatccaa aaggagaaag aggcggttgg aaagaaacgt
     6781 tgccagaaat tgcggatgaa attaatattc ttaacttgac cagtaagcca gaaaatcaag
     6841 gcttacttga tccctatgtg attatgaaga aaaagaaaga ctcagaaagt ttggcgattg
     6901 atatcctgac ctttttaaca gggatttcca gtcgggatgg ggagaagttc cctgtgttac
     6961 gcaaagccat tcgaacggtt acccaaagtg atcagcgagg attattacaa gtaatcgttg
     7021 aattgcgtaa agaggactca ccagtcgcgg aaaatatcgc ggatcacatc gagtccttta
     7081 ccgattatga ttttgcccat ttgcttttct cagatggttc gattacccag tcgattagtt
     7141 tagataagca gttaaatatc attcaagtag cggatttggt tttaccagat gcagaaacca
     7201 cttttgaaga atataccacc atggaattgc tgagtgtttc catgctaatt gttatttcca
     7261 cttttgcctt ggactttatc catagcaacc gagaaatttt caagattgtg gacctggatg
     7321 aggcttggag ttttcttcaa gtagctcaag gaaaaacgtt atcgaataaa ttagtgcgtg
     7381 ctggtcgggc catgaatgcc ggtgtttact tcgtcacgca aaacagtgat gacttgttgg
     7441 atgaacgttt gaagaataat attgggctaa agtttgcatt tcgcagtacc gatattcatg
     7501 aaatcaagaa aaccttggaa ttctttggat tagataaaga agatgaaagt aatcaaaaat
     7561 gcatgcgaga tttggaaaat gggcaatgct tgatgcagga tttgtatggt cgagtaggtg
     7621 tggtccaagt tcatccagtc tttgaagaac ttttccatgc ttttgatacc cgtccgccag
     7681 ttcaagagag aatggagtga ggagatgaaa aagaaacttt ttcgtatctt tggaattgtt
     7741 ttaatcagtt tggtcactct gataatactt ttgagcttag ttggaacggt agctgaggca
     7801 acaggtctgg ttgatgatac agttggagcc ggaaatcttt attcccaata ttcacttggt
     7861 aactatcagt tggatttctt tgtggatagt tcgtgggatt ggctgccttg gaattggggt
     7921 gatggcctag ggaagagcgt aatgtatgga ctttatgcca ttactaattt tatttggaca
     7981 gttagtctct acttatcaaa tgccacgggc tacgtggttc aagaagccta taagctggat
     8041 ttcatttcag atacggctga aagtattggg aagaatatcc aaaccttagc cggcattacc
     8101 gaaaatggac tccagacctc gggcttttac tttgggtttc tattattgat gattttagct
     8161 ctaggagttt atgtggcgta tacaggatta ttaaaacgag aaactaccaa agcagtccgg
     8221 gctgtcatta attttgtgat gatttttcta ctttcgggtt cgttcattgc gtatgcgccc
     8281 acctatatca caaaaatcaa tgattttagc tcagatgtca gcgaagcggc tcttagcctt
     8341 ggaaccgaga ttgtcgtgcc gaattcagaa agccaaggaa aggacagtgt ggatttaatc
     8401 cgagatagct tgttttccat tcaagtccaa caaccgtggt tactcttgca atttgatgat
     8461 tccaatatag aagaagttgg cgaagatcgt gttaacaaaa tcctgtctgt aagtccagat
     8521 gaaaataaag gcaaggatcg ggaagaagcg gtcaaagcgg agattgaaga taatgacaat
     8581 gcgaatctca gtattaccaa gaccatgaac cgcttaggga ccgtggtctt tttggtgttg
     8641 ttcaatattg gcatatcctt ctttgtcttt ctcctaacag ggattatgtt gttctcgcaa
     8701 attctcttta ttatctttgc gatgtttttg ccgattagtt tcttattgtc catgttgccg
     8761 acttatgaga gtttgggcaa gaaggcgatt attcgcttgt tcaatacgat tatgatgcga
     8821 gcaggagtta ctttggtgat tacgactgca tttagcatct ccacgatgtt tttcaatatt
     8881 tcggcaacct atccattttt catggttgct tttctgcaaa ttgtgacctt tgccggtatc
     8941 tatttcaaat tgggcgacat tatgaatatg ttcaatctcc agagtaatga tagccaatca
     9001 atgggaagac gggtcatgcg aaaaccgcaa atgttaatga atcgaacatt gcggcaactc
     9061 aatcgaaatg tgggacggac tttggctttt ggtggtggtg cagcagttgg aaataagttg
     9121 gcaaaggaac aatcaaaatc caaatttaag ccatccggtt cttctctacg aaagaattca
     9181 cgattaccga acgatcacga gataccatct gacttgaata aggaaaagcc aattccaaat
     9241 aataagaaac aatcccgaat gaatttggcc gggagaaaag tcggcaaggt tctggatacc
     9301 caagctttgg tgaaagataa gaccaaacaa gtaaaggatg gagtacggaa tacgccaacc
     9361 aacttgaaat acaacttcca taaaggaatt gaaaaaacga aaaaagcacc ggaagagttt
     9421 aagcgaggac tggtccaaga aaaagcaaat cgaggagagt tgcgagaaaa acaacaacaa
     9481 cgtagagacg aaaaaatagc tgaaaagcgc aaagtattga acgaaatagg gaatcctcat
     9541 gggaaaagaa gggaaaatgt tccgataaaa gcaaaggtcc aatctcaaaa ggatagagca
     9601 ccaaagcgga ttgtgagagc aaattcgaat cccgaaatca aacgaaaatt cgctagccaa
     9661 gaaatcattt caaaaggaat aaaccaatcc tcaagtaaga aaaattcttt tcaacaagtg
     9721 aaacggcggt ctactctgtc caaacgaacc aatcgaaaag tacaaaaaag tttgaaccct
     9781 catcccaaac caaggtcagg tgagaaaaaa tgaacgtaaa gaaattaagt gccatttcgt
     9841 taactttcct aacaatctct tttatgggta tcttgatgtg tgtgggctta ttgtttggtg
     9901 aagacagtga aggaagtagt agttcaggtg ctcctcctgg ggggagtagt gtctcagaag
     9961 aggttttgaa acaccgtgca atggtggaaa aatatgccaa agaatcggat ataacagagt
    10021 atgttccgat tcttttagcg attattcaag tggaatctgg tggcacaatg gaagatgtga
    10081 tgcaaagttc tgagtcagcc ggtttaccac cgaattcatt aagtaccgag gcatccatca
    10141 aacaaggatg tctctatttt gcgtctttgg ttaagcgttc caaagaatta ggttgtgatc
    10201 aagatagtat cattcaggcc tataactttg gcggtggtta tttggactat gtggcaaaaa
    10261 acgggaagaa gcatagtttt gctttagctg aatctttttc aaaggaaaaa tcttgcggtc
    10321 aaaaaatcga ttaccctaat cccatcgcga ataaggaaaa tggtggatgg cgctataact
    10381 atggcaatat gttttattgc ttattggtga agcaatacct aactacaaca cagtttgacg
    10441 ataaaacagt ccaagggatt tttgacgagg cgtttaagta tgaaggaacg gcttatgtat
    10501 ttggtgggtc aagacccgaa acaggatttg attgtagtgg cttgactcaa tggtgttatg
    10561 ccaaagttgg tctgaaactt cctcgggtgg ctcaagatca gtatgatgcc atgacccata
    10621 ttgacctaaa agatgccaaa ccaggggatt tggttttctt tcattcgact tatgatgccg
    10681 gtacttatgt gacccatgtc ggtatttatg caggggagaa tcgcatgttt catgcaggag
    10741 atccagtagg ctggacgaat ctaacagaaa gctattggca gcagcatctt atcggtgctg
    10801 gacggtacaa ataagagaaa agaggaaaaa gaatgaagat aaaaattgaa cggaatcaaa
    10861 aggaaaagag cctaaaaaag aaaaaagaac gagtcgtatc cgtgggtaag catcgaaaaa
    10921 tggtgcttgc cctttggctt ttattatctt gtagtcttac ttttggcgtt tataaaaatt
    10981 tcaccgccat tgatcaacat acaactcatg aaaaagtggt tattaaagag aaagtagtga
    11041 atacttctgg tattgaaaac tttacgaagg atttttcgaa agaatatttt tcgtggaaaa
    11101 ataacaaaga agcaattgaa aagagaatga acaacctcga acagtacctt acagaagaag
    11161 gtttcgcttt aagtcaagat atggttcgag cagatattcc cactaattcc gaagttcagt
    11221 cagtaaaagt cttagatgtt gaaaagagct cggaggaatt tgtcgtttca tttttagtgg
    11281 agcaaaagat tacagaggga aaaaaggcac aatcgatttc ttctgcatac cgagtgacga
    11341 tctttgaaga tgaaaacagg aattatatag taacgagttt gccaactatg attgcaaaac
    11401 ctgatagggc aaaatacaag acaaaacaag tagaaaatga ttcgaaaatt gatgccaaaa
    11461 ctacagaaga aatcgctgag tttttggaaa cgttctttaa attatatcca tcagcttctg
    11521 aaaaagaatt ggagtattat gttgaaaatg atgcgatgcg accaatcaat attgacttaa
    11581 agttttcgaa gttagaggat ccagtttacc tacaaaacgg aaaaaaaatt ctagtgagta
    11641 caaagataaa ataccttgat aatgtatcaa aaaccactag ctactttcag tacaaattaa
    11701 tattacaaaa aaatggaaac tggaaaatca ttgatgttaa ataataatga ctcaatctaa
    11761 atttatgaga agttataagt agtttaactt atttcaggca gaagtcgccc atcctctata
    11821 ggtgggtgat gaatgccgtt cggtaactcg aaaaccgaca attaagacat agtgcctttt
    11881 tattttaatc catgtcataa tcagtctata taagaaatgg ttgatatacc atggaattag
    11941 atacaaataa tcattcatta tttcttcttt gttaccacct tattttagta gtgaaacatt
    12001 gtaaacatct cattgatgat gtaatgttag cttatgcaaa aaactatctt tgaaagaata
    12061 tcagaatcac atcacattac cttagttgag tgaaatcgtg ataaagacta ctttcatatt
    12121 atgctcaaag cacaacctaa aaccgaatta acaaaattca gcaatgccta agctcatgtc
    12181 tgataaaatg agactttcta agggtcaaaa atttcctttg aatacgatca ttagcttaga
    12241 taaaagtaaa aaccttagaa ctacggggat agcttggtta ataagagata tcgctgttaa
    12301 taaagacata agcttgcaag tatgctctat tcccaagaat ctcccacttc aagcactaag
    12361 gatcgttaaa ttcagctaag tggcaagtag ttcactagac gataattatc tccatatttc
    12421 aatctcagct tttccatttt tcatagcaaa ttccgttatt tttatagcat ctaaaagatt
    12481 cagcttttcc actgatcttt caccactttt cagctttttt attgtgctta aattgatacc
    12541 agtacctttt gatattgaat tggaagtaaa atcattaagg gtttttttta ttaaattcat
    12601 atccgcaatt ccagcgttca taagaatgaa gattctcctc tcatagacta ctttgaaaat
    12661 ggtactacag tggctgttta tatatttcag taggttactg tagtggtcat tttattataa
    12721 ttagaaaagg aacctaaatc aaaaatgcta aagaaaattt tcatagtatt aaacctatca
    12781 tgactaaagc cacggaattc ttgataaaag agtatacttg caagcctatg tctttactaa
    12841 cagcgatatc tcttattaac caatctatcc ccgttgttcc taaggttctt gatgttttct
    12901 aaggcaatgc ttgtatacat agcccttgat caaaatattg atactaacgt tgacgtttcg
    12961 atcatgatgt gtacggcaaa taggacaagt ccattctcga attgtgaatg acttcttacc
    13021 atctgtgtgt ccacattctg aaccaatttg actagacgga aatcatttat ctatcttgat
    13081 gatttttttg acagaagtat cgaaaatctt tacataatct gggtgttgca ttcttatgca
    13141 gatgagagcg ttagctccgt attcataacc agttgcctct aaaacgtagt ccatcggtgg
    13201 atacctagct tgcggttgcc agtggctttc gcagtcttct tgtaatcaaa tcgagcatct
    13261 aattgagtac tagtattttg aagataatac ttgagttttt cggttttcag aagttcactt
    13321 catcttccat catccatgga aatcccactc acccatacgc aggcctccaa aaattcttca
    13381 acaatggttt ttcagacatt tttctgaata cctccttgtt ttttgatacg ccagatagtc
    13441 aggaaaaagg caacaaaaca caaaacaaag ctgcctaaaa aggtaatctt cattccatat
    13501 aaaaagacat ccggccgatc tgcgatatag ttagttactc gttggcccat cttagcagac
    13561 atcgcttgat ataagaccgt cgtagaaagc gaaatcccga tgaccatccc caaatttcgg
    13621 gcaaaggaat tcatggagcc tgccagtccc aaattttcga tagtgacaga actcataacc
    13681 atcgtattat ttggggactg gaacaaggca ttgccggcac ccatgatggc agtagcgaca
    13741 atgtacagcc acaaaggaga gtccactgac aaaaacatat acatgacttg ggttaccgac
    13801 aataaaccca agcctactaa tacaaaaatc tccgggccaa cccggtcggt caggtatccg
    13861 cttaaaggcg ccccgacgac catcatcaag ggaaagacca tcatcaacag tccggcatag
    13921 ctaggactca acccgcgagc attttgcaga taaaaaggaa tcactacatt aacaaagaag
    13981 ttggaagaaa aaatcaacaa ggctgtaatc aagctcatgg taaaaatctt gttcttaaaa
    14041 ataccgaaag aaatcaatgg agaggctgct ttcttttcaa cttttaaaaa gctgacaaag
    14101 gcaatcactg aaattacgaa cagtacaagg gggactggat ggaaaaagcc actttcttgc
    14161 cccaaaaaga ttgttccaaa aaggctgata atcgtagccg caatggcagc aaagccccct
    14221 ccatcgattg tatggccgct catggtgata tcttttggta agaatttttc agcaatcaac
    14281 atcgttacga ttcccaccgg tacattgatc caaaaaatgt acgcccaaga aaattgggac
    14341 aaaatcaagc cgccaagacc tggtccagca atcgagccta atgaaacaag cgcaccgatt
    14401 gctcccaatg cccgaccacg ttcatgtatg ggaaagactt ccgtgatgat tccggcattt
    14461 gtagccatag tcatactagc accaatggct tgtaccaccc gtgcgaacaa ttaaatacct
    14521 agcgaatgat tgaacccaca caacagcgag cccaagacaa agatcagcgt accaatccga
    14581 aatactttga ttttcccaca gctatcgcca attttaccaa acagcaacaa acaagaacag
    14641 acaatcatca gataaacgga cactacccat tccgcttgat tcattggtat gcccatatca
    14701 tctgagatgg taggtagtgc aatattgaca atactgccat ccaatgtgga catgaaggta
    14761 aacatagata tagcaatcaa aatccaccag cgattttttt ggacttttgc atcttcttga
    14821 taactatgca taataggatt tcctttctaa tgatcgtgta gctaagaaca atataaccta
    14881 tgtctactgc ccaacaactt ctcgcgactc tagccatagg aagcttgagt aatttcgatt
    14941 tgttattctc atgtaaccat gtaagtttga gatgctttat ttgaacttac tctatagtaa
    15001 ctagtgataa ttcgctttac tttcttctag caatttctaa aagtcgactt cattgttctt
    15061 cagattaata gtgtgagcta tctcgtgaga cgtaagaaaa tttccattct actttttccc
    15121 aattttttca tatttatggt gttgcaccta tttgttttcc aatttgcttt tcaaatacat
    15181 tgctatgata ttcaattcca taggattata ctaaat
//
LOCUS       DADQDV010000068        15145 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.070, whole genome shotgun sequence.
ACCESSION   DADQDV010000068 DADQDV010000000
VERSION     DADQDV010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15145)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15145)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15145
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.070"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..345
                     /locus_tag="J8S10_002298"
     CDS             <1..345
                     /locus_tag="J8S10_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630874.1"
                     /translation="SNIKTSTKLICKLFKLDKISNIDDVKSKILTRKVSEPVKLTAQD
                     KKNGIVLYGDDAKYNYNWDTSSEAEVLSIPTTDTSGEKVTFKINFITAISKLEYGKQK
                     KRDNNDQYLPKK"
     gene            426..1046
                     /locus_tag="J8S10_002299"
     CDS             426..1046
                     /locus_tag="J8S10_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630875.1"
                     /translation="MNINRVIKLIGAKNINKVRSEFIFPEDFFNWFFYQFSECKRLLG
                     ENYYLKGIGGFMGNVADEQNIIKGISEQTSELTVTKAFISNGESLKNVTARIRKENEV
                     DIVFGIDHECNSVIYVTQSANLILFENGCKDDFMVVYLYDILIPKLRSLYMSSESIFV
                     SEQKGSFSKKIGIEVIESIMCHNHITLEELEILIGQKNNNTKIQVS"
     gene            1747..2031
                     /locus_tag="J8S10_002300"
     CDS             1747..2031
                     /locus_tag="J8S10_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAZ9630876.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWQTTQPRLRDSLIFLEIQLENLHFLYTFLAAFFIPVNYTSLINKKEG"
     gene            2034..2951
                     /locus_tag="J8S10_002301"
     CDS             2034..2951
                     /locus_tag="J8S10_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAZ9630877.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            2944..3726
                     /locus_tag="J8S10_002302"
     CDS             2944..3726
                     /locus_tag="J8S10_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAZ9630878.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMIAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LILATLSVPVALTFITRSTSVSLLLSFLYIMGTAFVPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            3727..4407
                     /locus_tag="J8S10_002303"
     CDS             3727..4407
                     /locus_tag="J8S10_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAZ9630879.1"
                     /translation="MFLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            4400..5296
                     /locus_tag="J8S10_002304"
     CDS             4400..5296
                     /locus_tag="J8S10_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAZ9630880.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWVDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDSFIRLTVANPIKPGAQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            5491..7140
                     /locus_tag="J8S10_002305"
     CDS             5491..7140
                     /locus_tag="J8S10_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HAZ9630881.1"
                     /translation="MGQREFIVLIIIAVVILLVVLDIFSRLKVKETVRSNWGKIPYQP
                     RFDKEESLKDAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDYQLEKLIAFYQENPQLRERIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGVGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKMTTPLQKELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAVLNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLNYPKSIVEQAQKESLLFDEQRQWYPFD"
     gene            7734..8669
                     /locus_tag="J8S10_002306"
     CDS             7734..8669
                     /locus_tag="J8S10_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9630882.1"
                     /translation="MANALEINNLKKIYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDKDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYDTKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            8662..9432
                     /locus_tag="J8S10_002307"
     CDS             8662..9432
                     /locus_tag="J8S10_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9630883.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            9848..10831
                     /locus_tag="J8S10_002308"
     CDS             9848..10831
                     /locus_tag="J8S10_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HAZ9630884.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKDPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILETFEKEHPTLFSEQ"
     gene            11278..12315
                     /locus_tag="J8S10_002309"
     CDS             11278..12315
                     /locus_tag="J8S10_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HAZ9630885.1"
                     /translation="MSEKELMKVVGFYEGLPIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGSGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHML
                     GKVVVSGPFNG"
     gene            complement(12404..12727)
                     /locus_tag="J8S10_002310"
     CDS             complement(12404..12727)
                     /locus_tag="J8S10_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HAZ9630886.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRVLPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLAGILSLS
                     LIRLL"
     gene            complement(12714..13421)
                     /locus_tag="J8S10_002311"
     CDS             complement(12714..13421)
                     /locus_tag="J8S10_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HAZ9630887.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLVYAGSAQFITVSMLASHSPLLSIVFSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVIVV
                     VTLIGCGLGVWIKHAFF"
     gene            13507..13848
                     /locus_tag="J8S10_002312"
     CDS             13507..13848
                     /locus_tag="J8S10_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
                     /protein_id="HAZ9630888.1"
                     /translation="MVGLKRKELAGRRFTRIVSVGGGAKNLAWLQIQADIFDATVYCL
                     SVEEGPALGATMIAALGLGWFDTPESCCQNFIQYTDAVEPLLQNVEKYHKIYQQCRKI
                     YPATKEICHDL"
     gene            complement(14019..14867)
                     /locus_tag="J8S10_002313"
     CDS             complement(14019..14867)
                     /locus_tag="J8S10_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630889.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPHFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKLKKR"
BASE COUNT         4856 a         2580 c         3200 g         4509 t
ORIGIN      
        1 tcaaatataa aaactagtac gaaattaatt tgtaaattat ttaagcttga taaaataagc
       61 aatatcgatg atgtaaagtc caagatatta acaagaaaag taagcgaacc agtaaagcta
      121 acggcacaag ataaaaaaaa tggaattgtt ctttatggtg atgatgcaaa gtataactat
      181 aattgggata cctcctcaga agctgaggta ttaagtattc ctactaccga tacttcaggg
      241 gaaaaagtca cctttaaaat aaattttata acggcaattt ctaagttgga gtatgggaag
      301 caaaaaaaga gagataacaa tgatcaatat ctacctaaaa aataacgaat taatgatgca
      361 tatgttaaag ttgttttttt gaattaaaca actcaattta ttcagttata tgttcatcgc
      421 agcaagtgaa cattaatcga gttataaaat taataggagc taaaaatata aataaagttc
      481 gatcagaatt tatttttcca gaagattttt ttaactggtt tttttatcaa ttcagtgaat
      541 gcaagcgact cttaggtgag aattattact taaaaggaat cggcggattt atggggaatg
      601 tggctgatga acaaaatatt ataaaaggaa tatctgaaca aacatcagag cttacagtaa
      661 ctaaagcatt tataagtaat ggtgaaagtt tgaaaaatgt aactgcgcga attagaaaag
      721 aaaatgaagt agacattgtt tttggaattg accatgaatg taattcagtg atatatgtaa
      781 cacaatcagc aaatttaatt ctttttgaga atggttgcaa ggacgatttt atggtggtct
      841 atttgtacga tatactaatt ccaaaacttc gttccttata tatgtcttct gaaagtattt
      901 ttgtgagtga acaaaaggga tctttctcga aaaaaatagg tattgaagta attgaatcga
      961 ttatgtgtca taatcatatt acgctagaag aattagaaat tttgataggg caaaaaaata
     1021 ataacacgaa aatacaagtt tcttagaaat cattttttat tgagatatct agataaatga
     1081 tttattcttc aatcaaccaa ctcgccaagc tgaggtaatg ttttgaggta atgataacat
     1141 acaacttttt ataccctagt aaaactctat aaacaaagac ttattaattt cgcatgaaat
     1201 acattcctgt aaaatgcaat aaaatagagt tttgtttaac caggtcttaa gaaagcccgt
     1261 aaagcttcac agttctcaaa acgttaattg cgattatcgt tcgagttcac gagttacgag
     1321 aatcgtactg ggcgaagcaa tgctgagcgc agttacctta atcctaactt ttctggcact
     1381 ttccacaatt tggaaagtgc cttttttgtg tttttagcta tgttaatagg taggattctt
     1441 ggtctataat atcattcgat ctataaacaa acgggaaaaa gataaagtat catcaaacaa
     1501 tattatttat ccgcttctga ggttgtgaca gaagtggtca gcttcaagaa ataagaagga
     1561 atttacaaaa attgcttctc atgtttgata aatattgtga cttgtgaccg aggagttggc
     1621 aggagaacac cgtttattcg gaagaaggga ttgtgaaaag tcttttgtca taacctctta
     1681 tttggtagct aattgtaaat cccaaacggc atgtattatt tttcataagt ccgtttttaa
     1741 ggattaatgt tttcttttgc tttttatatg gtctggcttc agcgagaagt tccaacgcat
     1801 atacaaggac gtctgatgtc aacgataaca acgattacca tggtggccag tccacttgga
     1861 ttagcactgt ttggtgcgct ctttgattgg cagacaactc aaccacgtct gcgagacagt
     1921 ctgatttttc ttgaaattca attggaaaat ttacactttc tttatacatt tctggctgct
     1981 ttctttatac ccgtcaacta tacttcactt atcaataaga aagaaggata agtatggatt
     2041 ttggaaatga aacggtcttg aaagcaactg gtataaccaa aaaatacggt gctgccaaag
     2101 cattagataa agtatcgatc gaaatcaaac gtggaatgat ctatggtttg attggggaga
     2161 atggagcggg taagtctacc tttatgagaa ctattatggg tttgatctcg attgatgaag
     2221 gttcgatcga attatttgga acgacggatt tgcaggcagc aagacgacgt atgggtcaat
     2281 cgattgaaac ccctgctctt tatccagaat taactgcaag agataaccta cgtatccaag
     2341 cagcgaacgg cggtgtgtcg gatagagaaa tcgaagacct gctgaaaatg atgcgattgg
     2401 aaaatacagg gaaaaagaaa gcaaagaatt tctctttagg tatgcgccag cgtttagcta
     2461 ttgcaaatgc actgatcacg aatccagaat ttttgatttt ggatgaaccg acgaatggga
     2521 tggatccagc agggatggca gaaatgcgag aaatcatcca acgtttggta aaagaacggg
     2581 gcatcaccgt cttgctttct agccacttgc tagatgaatt gtcacagatc gccactcact
     2641 acggtatttt gcatgaagga cacttgatca aagaattatc gaaagaagaa ttggcacaag
     2701 aatctcgtca atttataaaa attgacactt cggcgacgga acaagcagta acggttctcg
     2761 actctcttgg ttatagggat tattttgtcc aatctagccg tgttatccag ctttttgaag
     2821 gaattgacca agtagcagcc atcaatcaag cattggtaga ggcaaaagtt cctgtggatg
     2881 gtatccacct agttgggcaa aaactggaag attatttctt acaattaact ggaggcaatc
     2941 cacatgttta atctattaac tgctgaaaaa ataaaagtat ggaagagccg taaaatgtgg
     3001 gtctcactag gactgatggt cgtacttccg cttttttatt cttggaacga atggtatatg
     3061 catacaaaat acggcaatga attaaaccaa gcaacggata cagtcatcaa cggtgcaaca
     3121 gggattttaa tggtggaaaa aatggctgca tggattcttc tggctttcgc agcatttgcg
     3181 tgcttttata ttggggaaga atttcaaaac ggtacgattc gcaatacgtt atctttagga
     3241 cggaatcgaa tgacttatta tgtgtcgaaa cttctcgtta cgcttttgat cacaacactt
     3301 ggcgtggttt tgattacggg gctagccatg attgcttaca cacttgcttt cggatttggt
     3361 gaagttgagg gaatcaaaaa ctatggaaat tatgttctaa aagtatttcc tgtattgctt
     3421 ctgctgatat tagcgacatt atctgttcca gtggctttga cattcatcac tagaagtacc
     3481 agtgtcagtt tgcttctttc ttttctttat atcatgggaa cggccttcgt tcccggtgtt
     3541 ttcgcaaaaa tcaaaggctt ggaatttcta acggagtggt ttacggaaac gtggctcatg
     3601 tatacggact ttgcgcaaca agcaacttat tcgcaagcac cgaaaatgat tctggtcagt
     3661 ctagtaacaa tcgtggtatc atcagctcta ggaatgttta ttttccaaaa atctgacatt
     3721 aagtaggtgt tcctgctgga aactattttg attatcgaag acgatgaagc tgttcattct
     3781 ttactggagg aggttcttga acagagatac aaacttcttg atgcttattc aggtacggaa
     3841 ggaaaattat tgttaagcac atatcctgtc gatttgatcc ttctagatct catgcttcca
     3901 gggctttcag gtgaagcatt gttagcagaa atccgacaga catcgaatgt tccgatcatc
     3961 gttctttcag caaaaagcga tcaaagagat aaagtttcct tgttggcagc aggagcggat
     4021 gactatgtga cgaaaccatt tgatatcgaa gaactgttgt tacgaatcgg catccaactt
     4081 cgtcatcaga cttctgtcca agtaaaagat ctgtcgcaac gcatctatta caaggaaatc
     4141 ttactggaca aagagtcgag ggatgtaaat gtgaatggtg tggctgtcca tttgacagga
     4201 agagaattcg atctgctgaa gcttttttta gaacatccga aaaaagtatt ttcgcgagca
     4261 aatctttatg aaacagtttg gcaagaacca tattttgata gtgagaaaac agtgaatatg
     4321 catatttcca atcttcgagg gaaactagca aaggcacatg ctgtgtatat tcatacggtg
     4381 tggggagtgg ggtttagatt tgattaagtg gctgttgctt ctcgttgtta tctttatggg
     4441 aagttttatt ttcttcctgc aaagggaaat caagagatta actaagaaaa tcgccactct
     4501 ttctgaacga caagaatatg gtggtcgtct ttcagtcgaa tttcgagaaa agaatctaat
     4561 ggacctagta gatgcactga atacatgggt ggatgaaaat gaacaaaaag gacaagcatt
     4621 tcaagaaatg gaagaaaaca tcagactatc gatcgtcggc ctttctcatg atctcagaac
     4681 tcctttgact gctattaacg gttatgtaca attactggaa caggtagagg atacggagaa
     4741 acgggagaag tatttaacga tcatcaaaca atctgttgca agattactca gtatgacgga
     4801 tcagttttat gatcttgctc gaatagagac gaagcaaaaa gaaatggatc tccatacgct
     4861 ttctttttct aaagaggtgg aagaagtatt tttctctttt tatgaacaat tttctgagaa
     4921 aaatatcgag gtagcgttcg ctgaacactc gataaataca actgtattag cagatccgct
     4981 catgttgctg cgagtgctgc aaaatatcat acagaattta ttgcgttatg cagatggaca
     5041 agcaaaggtg acattttcaa aagaggattc attcattcga ttaacagtgg ccaatcctat
     5101 caaaccagga gcgcaaacct ctgttgaaaa agtcttccag cgtttttata ccgaaaatac
     5161 cagccgcaca aatacggaat ctagcggaat cgggctttac ctgtcaaaaa aattggtgga
     5221 aggaatggga ggagagatga ccgctagatt agacgggggc atcttctcca tctccgtcaa
     5281 gttgcggagg gtttaattgg ctctaattta cctgaagtga atgacaaaaa attgtatctc
     5341 gttttaaaga catcttcttt tttggaaggt gtttttattt tggtgtgatt gatacgaatt
     5401 aggtaacgaa gacagttatt tttgtacccc cttttcaaat agcgcaacag tgctatacta
     5461 aaactaacaa atcaaggaac ggagagggat atgggccaaa gagaatttat cgttttaatt
     5521 attattgcag ttgttatttt attagttgtt ttagacattt tttcacgttt gaaagtaaag
     5581 gaaacagttc gtagtaattg gggaaaaatt ccttatcaac cgagatttga taaagaagaa
     5641 agtttgaagg atgcgtggct cacggagaaa aaattccgtt catgggatag tgaaatcgac
     5701 gatcttactt ggtatgactt ggatatgttc gaagtatttg aagggatcaa cagtacctat
     5761 tctagtgtag gttcagaagc gttgtatcag cgtttacgta gctttgattt tggagaagat
     5821 tatcagttag aaaaactaat tgctttttat caggaaaatc ctcaactgag agaaagaatc
     5881 caatatcaat tcgctcgttt aggaaaaaaa gatcataatt ttgcaaaaca atatctagcg
     5941 gatggaaaaa gtaaaaagat tggacgcgta ggtttattta tttttcttgg cttgcttccg
     6001 ctggtgggtg taggtttgct tcttttaggg caagtactag gaatctatct agcaatcggt
     6061 ggcttagtat tcaatacggt ctattatcta gtgaagaaac aaacactaga aacagagctg
     6121 aatagcatga gttatttggt ttcaacgatt tcagccgcca atcagttagc aaaaatgacg
     6181 acaccacttc aaaaagagct gaaacagcaa actaaaccat taagagacat ccctaaatta
     6241 ggtttttcat ttcgaatgaa gagcgggagt gaagcagaat tgatttttga atatgtcaac
     6301 atcatgttca tgctgccatt tatctcctat catttcgttc tcactaaatt agaaaagcat
     6361 tcaactgaag ccatcaagct gtgggaattg ctgggagaat tggaagttgc agcagccgtt
     6421 ttgaattatc gcacctatat gccgatcact tgccgaccag agtttactga gggcggtgtg
     6481 acagcgaaag atatctatca tccattgtta aaagaagcgg tagttaatcc agtcaactgg
     6541 cagaagaata cattagtcac gggttccaat gcatcaggaa aatctacgta tgtcaaaagt
     6601 atagccatca gctgtattct agcacagacg atccaaacag cgattgcaga acagtttacc
     6661 ctgcaacctg gacatgtgtt gacttccatg gcaatcgaag atgatttatt tgaaggcgac
     6721 agttattttg tttcagaaat caaatcgatc aaacgtttgc tggaccaagt ggcttccaaa
     6781 gaacgctgct actgcttcgt agatgagatt ttaaaaggaa caaatacgat cgaacggatt
     6841 gcttcttccg cttcagtcgt tcggtggctt gcggagtatc catctttagc atttgtcgcc
     6901 acacatgata tcgaattgac agagatttta aagaattatt gtgagaatgt ccactttgaa
     6961 gaacaagtaa cagaaggaaa aggaatcagt tttgatttca aattaaaaga aggaccttca
     7021 aggacccgaa atgcgattgc cttgctgaaa gttttgaatt atcctaaatc catagttgaa
     7081 caggcccaaa aagaaagttt gttgttcgat gaacagcgtc agtggtatcc gtttgattaa
     7141 ctttatcaaa cgaagcatga tgcgtgggtc caaaaagacg attatcaaaa gaagtacatt
     7201 gatgccaaaa aagtggcaga attcaatggg aacgagtctg ctgtccagat gatcttggaa
     7261 gatttagcaa aagacgatac aaaataaacc acgctgtctt ccttctagca gcttttatcg
     7321 aaaaaactta gcatcagcga cgagacgcac gttccatggc aaagttctcc gtaaaacaaa
     7381 cagcgaaaac agaaattgaa aataactatt tccattttat ttatttcggt taaaataaaa
     7441 gaaaaaagct ttcgataaaa ggacggagga aagcttaaca tgaataaaaa agacaagaac
     7501 ctcagttata aggatcttct atatgtcatc gtagtagttg ctgtcggtac ttttatgatt
     7561 ttaaaagttc cagagttgtt tagatagtta ttctatcgaa gatgatcatg aactagaaaa
     7621 cacatctcct ctttgttagc aggtgtgttt ttgtgtggaa gccaagttgt tttttcatct
     7681 gctgtattcc atgatacaat taagaatcat gtctataagg agataggaaa taaatggcaa
     7741 atgcgcttga aataaataat ttgaaaaaga tctatggaag tggggtcgaa gcattgcggg
     7801 gaatcgatct ttcggtgaaa gaaggagatt tctatgcgct attagggcca aatggagctg
     7861 ggaagtctac aacgatcggg attattactt ctttagtcaa taaaacatct ggaaaagtga
     7921 atgtcttcgg ttatgatctg gacaaggatc tagttcgagc aaagcaacag attggattgg
     7981 ttccacaaga gttcaatttt aacccttttg aaacggtcca gcaaatcgtc gtgaatcaag
     8041 caggctacta cggtgtctct cgcaaagaag cgatgaaacg cagcgaaaaa tatttgaagc
     8101 agtccaatct ttgggaaaag agaaatgtcc gtgcacgtat gctttccggg ggaatgaagc
     8161 gaagactgat gattgctagg gcattgatgc atgaaccacg tttgctgatc ttggatgaac
     8221 caacagcagg agttgacatc gagttgagac gcgagatgtg ggagtttcta cgagaattga
     8281 acgaaaatgg tacaacgatc attttgacga cgcattatct agaagaagct gaaatgcttt
     8341 gtcgcaacat cggaatcatc caatcgggtg aactgatcga gaatacaagt atgaaagagc
     8401 ttctgtcaaa actgcaattt gaaacattta tctttgattt agcgccatat gataccaaac
     8461 ctgtgattga aggatatgct tgtacatttg aagatgagca gacaatcgct gtcgaagttg
     8521 aacgaaatca aggggtgaac ggaatcttcg atcagcttac aagacaagga atcaaagttc
     8581 tttctatgag gaataagtcg aatcgtttag aagaactgtt cttgaaaatc acagaagaaa
     8641 ataatcatac ggaggagaaa aatgtttaat ctttatttta ctgcattaaa aagtttagct
     8701 atcaaggaaa cgaaccgcta tttgcgtata tgggtccaaa cactggttcc gccagtgatc
     8761 acgacatcct tgtattttgt tattttcgga aaaatgatcg gtgggcggat cggtgacatg
     8821 ggtggttttt catatatgga attcatcgtt cctggtttga ttatgatgtc tgctatcact
     8881 agttcgtatg ccaatgtttc ttcgtccttc ttctctcaaa aatttcagaa aaatatcgaa
     8941 gaaatcttgg tagcacctgt tcctacgcat gtgattattt ggggctttgt gattggtggt
     9001 gtgggtcgca gtattctcgt cggctctctc gtaacgatca tttccttgtt ctttgtacca
     9061 cttcatgtgt attcatggtt catggtcatc attacattat tgatgacggc aatcttgttt
     9121 tcattagcag gactgctcaa cgggattttt gctcagtctt atgatgatgt atcgatcgtg
     9181 cctacatttg tcttgcagcc gttaacttat ctaggtggcg ttttctatgc catctctatg
     9241 ttaccgccct tttggcaagc tgtttcaaaa gtcaatccga tcgtttatat gatctccggt
     9301 ttccgttacg gattccttgg aacgatcgat gtgccagtag caacatcgat gatcgtactt
     9361 gtgttattca tcgttgtttt gtacgccgtt acttggtatt tgatcaataa aggaagagga
     9421 ttgagaagtt agaaaagagg ttgtgaaatc agcgttttga cctgagtatt agagaaacaa
     9481 acgggaaaat agttcctcat attttgttgt tttttgagcg aataccgagg gtcagctgat
     9541 tgaacaccgt ttagtggaga ggttgtgaaa aagctgttct gcatcaagta ataagaacag
     9601 ccaaacaaaa atagctcctc ctatttttcg tttggttgga cttattaccg cagatgcaag
     9661 cttttgaaca ccatttattc cggaaaatgg actgtgataa gatttttgtc acagtctttt
     9721 ttttgctcaa tcagaaacat cttttaagct gttcactttg cttctttttt tgtttcctag
     9781 tataatgaca atgtttttga gaaagattgc gacttcactg cttgatagaa tggagagtaa
     9841 caaataaatg actactaatt tttggaaaga gctgccaaag cctttttttg ttttagcacc
     9901 aatggaagat gtaacagatg ttgtatttcg ccatgtcgta aagcatgcag cagcaccgga
     9961 tgtcttcttt actgagttta caaactcaga cagtttctgt catccagatg gaaaagacag
    10021 tgtacgagga agattaacat ttacagaaga tgaacagccg atggttgccc atatttgggg
    10081 agacaagcca gaatttttta gagaaatgag cattgctatg gcagaaatgg gcttccaagg
    10141 aatcgatatc aacatgggct gcccagtccc taatgtagca gaacgtggaa aaggcagtgg
    10201 cttgatcctt cgtccagaag tagcggcaca attgattgaa gcagctaaag ctggcggttt
    10261 gcctgtcagc gtcaagacgc gtatcggcta tacggaaatg tctgagatgg aagaatggat
    10321 cagtcaccta cttcatcaag atatagccaa tctttctgtc catttgcgta cgcgtaaaga
    10381 gatgagtaaa gtagatgcac attgggaagt cattcctaaa atcattgctt tacgtgacca
    10441 aatcgctcca caaacactaa tcacgatcaa tggagatatc cccgatcgcc agacaggaga
    10501 agaattggcc gagaaatatg gcgttgatgg catcatgatt ggccgaggga ttttcaagaa
    10561 tccttatgca tttgaaaaag acccgaggga acatacagaa aaagaactga tcggactact
    10621 tcgtctgcaa ctagatctgc aagatcatta ttcagaaatc atcccgcgtt ccatcacagg
    10681 actacatcgt ttctttaaaa tctatatcaa aggatttcca ggagcaaatg acttgcgagt
    10741 tcagttgatg aatacgaaat ctactgatga agtacgagag atcttagaga cctttgaaaa
    10801 agaacatcca acgcttttca gtgaacaatg atttcttgct tgaacaccgt gaattagagg
    10861 tcgtgaaaaa gctgtcctgt atcaagtaat aagaacagcc aaacaaaaat agctcttcat
    10921 attttgtcgt tttttgagct aataccgagg gtcagttgat tgaacaccgt ttatatcaga
    10981 ggttgtgagc ctgccgttta actctgagtc acaaggagca atttcaaaaa acagcttctc
    11041 atgtttgatg aatattttga cttgtgaccg aagagttggt aggagaacac cgtttataag
    11101 aggttgtgac aaaagtcttg tcgcaacctc ttttttaacc aaaaaagtgc aaatagttta
    11161 ctttaagtaa gagaataatt atgatgaata aaaaaggtgg aacaaatagc atactatata
    11221 tattgaaatg aacactgtat ggatgctcca acttgatgaa gctaaggagg aattcgtatg
    11281 tcagaaaagg aattaatgaa ggtagtcggt ttttatgaag ggttgccgat cgatgatcca
    11341 aaaagcttta ttgatgaaaa agaacagata cctgtaccca gttcacggga tcttctggta
    11401 aaagtcaacg cagtatctgt taatcctgtc gatacgaaac ttcgccaaga taacgggata
    11461 agaaatgctt tacgtatctt aggttttgat ggagtcggga aagttgttgc tgtaggtgac
    11521 gaagtgcaaa aattttctgt cggcgatcgc gttttttacg caggtacaac aacaagagca
    11581 ggaagcaatc aagaatacca actagttgac gaacgtattg tcgctcttgc accaaaaaat
    11641 ctttcagatg aagaagctgc agccttgccg ttgacctcat tgaccgctta tgaattgtta
    11701 tttgaaaaat ttggtctaac tccagaagaa aatgccaatc gcgggaaaaa aatcttagtg
    11761 atcaacggat ccgggggcgt cggttcgatt ttgaatcaac tagcgcattg ggctggccta
    11821 gaagtctacg cgactgcaag tccgaagaat tttgaatggc tgaaaaaaac aggtgtagac
    11881 tatccaatcg attatcatca cgacttaagt aaaagttttc gtgaattagg aatcgatcaa
    11941 gtagagtatg tcgctgtatt attcgatatt acccgctact ttgatcaaat caagcacctt
    12001 gtccgaccat ttggacatgt gggaacgatc gtagggatca aagagccgtt agatataggt
    12061 gtttggaaaa accaatctat cagcttcgac tgggagtata tgttcgctaa aacagactat
    12121 aactatgaaa tcgaaacgca aggagaagct ttagcgcaca ttgctgcttt agcaaatgaa
    12181 gggattatcc gcagtacatt gagcaaggtc tattcagatg ggatgaatgc gaagaacttg
    12241 aaacaagcaa ccaaagacgt agaaacagga catatgttag gaaaagtcgt tgttagtggt
    12301 ccgttcaacg gataagcaag aatacgccga tttttttctt atttgacttt gataaaaaca
    12361 agagcgcatg acagtaattt gccataagct cttgtttttt tatttataat aagcgaatca
    12421 acgaaaggga aagaattcct gccaagacga tcaccaataa gctttttgaa agaatagcag
    12481 ctaaaagtgt aggaactgaa gccaaagcat tttcgagatt gatctgcggc agatgtccga
    12541 tattttgggt aaatagactg ctgaaccata aagcagacat aatgacgatc gggacaaaac
    12601 ttaaatactc aagcaacggt tgcggtaaat cgaatttttt cagtaagaca aatggtagga
    12661 ccctagaaag ccaagttgct aaagtacaac ctaaaatagt cagcaatgta aactcaaaag
    12721 aaggcatgtt tgatccacac ccccaatccg cacccaatca gtgttacaac tacaatcact
    12781 aagttgcttg ggataaaaat cagtccgaca tataccagaa tcaaagtgag accaatcagg
    12841 atcaactgta atcgtttaga ggtgtttcta tcagaaatga cttgaagata aagtaacccg
    12901 ataaacatag cgacgatggc gaaatccaaa ccaaactttt tcggatcagt aataaaattc
    12961 cctaaaagtg cgccaacaag agaagaaccc acccacgtca aataagaaat ccaattagct
    13021 gtattcatcc aacgaaagtt taacttttgt ccagtatagt tcaatttatt cattcccagt
    13081 gcgaaacttt catctgtcag caatgtgcca atcagcagat tttgaagcag ccgatttttc
    13141 ttgaaataag gagcaatcgt catactcatc agaatcattc gggaattgac tagaaaggtc
    13201 gagaaaacga tggaaagcaa tgggctgtga ctagcaagca tgctgactgt gataaattgg
    13261 gcagaaccag catagaccag cagggacatc aacgtgacga ctagtggatg aaatccggca
    13321 gctttcccaa cgataccaaa tgcaagtcca ataccgatat aaccgaaaac ggtaggtaac
    13381 gtgtctttga tcgcagtttt tatatctaac ttttcatcca ataacaaaac tcctttagca
    13441 cgacataaat tttcataatt gtcgttaaac ttgtgaatat tctaaatttt taatgagcat
    13501 ttgtcaatgg tgggattgaa acgtaaagaa ctagcgggtc gcagatttac acgtattgtt
    13561 tcggtgggag gaggcgcgaa aaatcttgca tggctacaaa tccaagctga tattttcgat
    13621 gcaacggtct attgtttaag tgtggaggaa ggacctgcat taggcgcaac aatgattgct
    13681 gcactagggt tagggtggtt cgacacacct gaaagttgtt gtcagaattt tatccaatat
    13741 acagatgcag tggaacctct cttacaaaat gtagaaaagt atcataaaat ctatcaacaa
    13801 tgccggaaaa tctatccagc aacgaaggaa atttgtcatg acttataaaa caaaacgcgt
    13861 acctaatagt caaatgacta atattgggta cgcgttaagt cttctttact tcatcctttg
    13921 catgattcgt gtttttaaag caaggtctgc tgtatttctt gtggatttag gatggttgtt
    13981 atcgtttact tgctattttt cattgaaatc gtctttcttt accgtttctt tagtttttta
    14041 tctatttttt tcttttggtt agaaaattct ttttcccgaa agtcttcttt caggattttt
    14101 atagagtagc gttttgaata agaggcgtca gtatgatcga cttggcagac gaaccaagag
    14161 aacatttgcc ttttttctgc atgaggtgct tctgctaata attctttcca taaataataa
    14221 cagtcctcta tcagaagaag ggttcgttca tcctcaggct cccaatagaa tgtttcgaga
    14281 gtagcaatca cttcattgat caattcgaat gcgggaagat aggcattttg ctgaataagc
    14341 gattcaactg cttcttggat gaactttcgc atctccatga tgaacttcgc tgttttcctg
    14401 tttttgtttt tcttgataat atgatcgtat ttatggatga tagttgttaa tttatctgaa
    14461 taatttattg catgaaatgg catcttaact ttgaagcgtt cgataaagtg cggatgttct
    14521 ataagaatct ctgttaaaag ctcccgtaca agagaggaac tagcggagga aacaagggac
    14581 gagagttcgg aaagtgagta gttggatttt tttattggac gttcttcgta agcgaataag
    14641 acagcagcca tgtgtttgca tttttttcct tctatggcat atagacaatc acaagtcatg
    14701 ttggtctttt catcccaagt gatcactacc ttataatctt ccgtgccaga aactgttgcg
    14761 gacaagtact tgcttgtata gttcaaatga cggacaaaac cgtgcagatg atagctgtaa
    14821 ccgcgttcca aaacgttttc aggaaaatac tcaagccaat tattcatcta gttctccttt
    14881 catgaaacac ttatttatat ttagtataaa gaaacgttta agaaaaaagt agctgatttt
    14941 acatatttga taatcacttt tgctcgaatt gtcaaaaatt cattctcctt ttcttttctt
    15001 agagaatgtg agaaaaagta aaagaatagc gtgttttaaa gatggaactt tttttgtttt
    15061 ttatttatct gacaaaaatg aagtgatttt gttagaaata aataattgtt ccaattgata
    15121 aaagaggtat gatgtatcgc aaaga
//
LOCUS       DADQDV010000069        14994 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.071, whole genome shotgun sequence.
ACCESSION   DADQDV010000069 DADQDV010000000
VERSION     DADQDV010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14994
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.071"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..608
                     /locus_tag="J8S10_002314"
     CDS             <1..608
                     /locus_tag="J8S10_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630890.1"
                     /translation="ENQLFAGDVLEIVLNDQAGEAAAKGVQNKPSTNDEIGNHNPSDT
                     PVVYHDAPPFAPATKIVVEGGLSFLAPSKLDCGQIKATGLTQEAFGQMDIQEKLWIYD
                     QRETKSPWILTIKLSQPFTTDAGFSMQDVLYFKKAEEYQLVNEEELEIVRGQNSTNVQ
                     TDYSEYLNNGRAFKLVLTKENQIAGNYSAEMTWTLADAPTE"
     gene            628..1656
                     /locus_tag="J8S10_002315"
     CDS             628..1656
                     /locus_tag="J8S10_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HAZ9630891.1"
                     /translation="MNRIWNKSHRNNCSLLLILLLGFILWQTPVHASEFNFAVDFELP
                     ANQIDKNKTYINVRMEPGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESK
                     SKFDETLSYDMKNLAKTVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKEN
                     VSNKSTVGVVNQFSQVKAILIRNSEKESSPNLKLKKTYADQSDGRNVIKANLQNPNAS
                     YMFGLTTSVEIYKKETKEPYLSIKKEKIDVAPNTNFDLLVPLEGKKLAPGHYQAVVKG
                     AWKEKRWNLHTDFEITDDAADQLNEKDIDLKNQPETFDWRWLILVGVILIGLFAGLFI
                     LKERRKKK"
     gene            1653..2411
                     /locus_tag="J8S10_002316"
     CDS             1653..2411
                     /locus_tag="J8S10_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HAZ9630892.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPNEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QNGTDSTGTATQVQNFVQVTDKSGIYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGTPSTISGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEGKA"
     gene            complement(2497..3237)
                     /locus_tag="J8S10_002317"
     CDS             complement(2497..3237)
                     /locus_tag="J8S10_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAZ9630893.1"
                     /translation="MKKYFIIEDNQFHSEWIIKELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            3298..4551
                     /locus_tag="J8S10_002318"
     CDS             3298..4551
                     /locus_tag="J8S10_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAZ9630894.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGFIALMVVTLL
                     FPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGLRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            4852..5100
                     /locus_tag="J8S10_002319"
                     /pseudo
     CDS             4852..5100
                     /locus_tag="J8S10_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877177.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            5222..5548
                     /locus_tag="J8S10_002320"
     CDS             5222..5548
                     /locus_tag="J8S10_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HAZ9630895.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLQLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEF"
     gene            5616..6329
                     /locus_tag="J8S10_002321"
     CDS             5616..6329
                     /locus_tag="J8S10_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HAZ9630896.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYLVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PIFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEEKEIVTLITCGDMDAVTRLVVQGELESVTP
                     IKDATDDMRSAFNLETKTF"
     gene            6639..7491
                     /locus_tag="J8S10_002322"
                     /pseudo
     CDS             6639..7491
                     /locus_tag="J8S10_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
     gene            7612..9477
                     /locus_tag="J8S10_002323"
     CDS             7612..9477
                     /locus_tag="J8S10_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAZ9630897.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            9525..10934
                     /locus_tag="J8S10_002324"
     CDS             9525..10934
                     /locus_tag="J8S10_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HAZ9630898.1"
                     /translation="MEQLLPNQLEGAYDRDGKGLSVADAMPGGKQRFAIIGSEEFDWT
                     IDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPNGDEGTPNEAGL
                     EFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYERFAQTVLERYS
                     SKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVASSKAVKIGHEL
                     RSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGEYPAYTARTHKK
                     YGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSEGNLLGGVKNPF
                     LEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDGTIIDDYRIDYL
                     RRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGNGTLNRS
                     KKKSFDWYKEVIASNGVNL"
     gene            11042..11743
                     /locus_tag="J8S10_002325"
     CDS             11042..11743
                     /locus_tag="J8S10_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAZ9630899.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            11902..12381
                     /locus_tag="J8S10_002326"
                     /pseudo
     CDS             11902..12381
                     /locus_tag="J8S10_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015510350.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            13229..13804
                     /locus_tag="J8S10_002327"
     CDS             13229..13804
                     /locus_tag="J8S10_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HAZ9630900.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            13804..14244
                     /locus_tag="J8S10_002328"
     CDS             13804..14244
                     /locus_tag="J8S10_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HAZ9630901.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            14260..14961
                     /locus_tag="J8S10_002329"
     CDS             14260..14961
                     /locus_tag="J8S10_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAZ9630902.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
BASE COUNT         5066 a         2485 c         3161 g         4282 t
ORIGIN      
        1 cagaaaatca actttttgca ggagatgtat tagaaattgt attaaacgac caagcaggag
       61 aagctgctgc taagggtgtg cagaacaagc caagtaccaa cgatgaaatt gggaatcaca
      121 atccaagtga tacgccagtt gtttatcatg atgccccgcc ttttgcacct gctacgaaga
      181 ttgtagtaga aggtggtctc tcatttcttg ccccttccaa actcgattgt ggtcagatca
      241 aagcaactgg gttgacgcaa gaagcatttg gccaaatgga tatacaggaa aaattatgga
      301 tttatgatca gcgagaaaca aaaagtccat ggatcttaac gataaaatta tctcagcctt
      361 tcacaaccga tgcaggattt tctatgcagg atgtcctata tttcaagaaa gctgaggagt
      421 atcaattagt gaatgaagaa gaactggaaa ttgtcagagg acaaaattca acgaatgtgc
      481 aaacagatta ttcagaatat ttaaataatg gtcgggcgtt taaacttgtc ttaaccaaag
      541 aaaatcagat agctggtaat tactcagcag agatgacatg gacattagca gatgcgccga
      601 cagaataaag atcaaggaga atgattgatg aatcgaatat ggaataaaag tcatcgaaac
      661 aactgctctt tacttctgat ccttctcctt ggattcatcc tttggcagac acctgtccat
      721 gcctccgaat tcaattttgc ggtagatttt gaattaccgg ctaatcagat tgataagaac
      781 aaaacatata taaatgtaag gatggagcct gggaaaacac aggaaatccc ctacacggtc
      841 tttaaccgaa cagataaatc agtaacagtt gagacattga tccactccgc tacgacgaat
      901 tcaaacggtg tgatcgaata tggagaatca aaaagtaaat ttgatgaaac attaagttat
      961 gatatgaaaa acttagcaaa aacagtggga gaaataactg tccctcctca aagtgcggtc
     1021 actgagacac tttcactgaa agctccagaa aaagagctgg ctggtgtggt cgcaggagga
     1081 atcacgtttc aagaaaaaaa agagaacgtt tctaacaaaa gtacagttgg tgtcgtcaat
     1141 cagttttctc aagtgaaagc aatcttgatt cgaaatagcg aaaaagagtc ttccccaaat
     1201 ttgaaattaa aaaaaactta tgcggatcaa agcgatggaa gaaatgtgat taaggcgaat
     1261 cttcaaaatc caaatgcttc ttatatgttc ggcttgacta catcggttga aatctacaaa
     1321 aaagaaacaa aagagcctta tctttcaata aaaaaagaaa aaatagatgt agcacccaat
     1381 acaaattttg atttacttgt cccattagaa ggaaaaaaat tagctccggg acattatcaa
     1441 gcggttgtga agggtgcttg gaaagaaaaa cgctggaatc tccataccga ttttgaaata
     1501 actgatgatg cagcggacca attgaatgaa aaggatattg atttaaaaaa tcagccagaa
     1561 acatttgact ggcgatggct gatacttgtt ggagtcattc ttattggctt atttgctgga
     1621 ttatttattt taaaagaaag aaggaaaaag aaatgaaaaa aacaattgca ttaagtaccg
     1681 ttctagctgg aagtctatta ttatgtacac aaagtgtttt tgctgagaat aagagctcag
     1741 ccactacaga aggaacgatt tctgtaacaa aaccagatgc cgcaaatcct gaagacgttg
     1801 ttccagttcc tcctgttgat ccaaatgatc ccgatacgcc gtttacacct aacgaaccaa
     1861 atcagggaac atccggatta ctgacgattg accaagctcc agatcttgat tttggaacaa
     1921 tcaagttagg tacagcaaaa acagtatatg ctgcattaca aaacggaacg gacagtacag
     1981 ggacagcaac acaagtacag aatttcgtac aagtaacgga taaaagcgga atttatgccg
     2041 gttggaaact atcagtcaaa cgaacagaat ttattggtac aacatctgat acgaataaac
     2101 taactggttc aaaggtgaaa ttcaaaaacg ccgtgattcg aaatagcgca actaatagca
     2161 gtggaacgcc atctactatt tctggtactg gcgctgaagg aattgagatc ccagcagatc
     2221 aggcagtaga tctagtaact gcaggagcaa atgaagggat tggcacatgg atttattcat
     2281 taggagagaa tgtggaacaa gggagacaat cagtggaatt atttgttcct gtatccaatt
     2341 atgccgtaga caactacgtt tcaacattca catggtcgtt aacagatgct cctacagaag
     2401 ggaaagcgta aaatcaaatc aatgacttca gggagtggag ccgattcaag gccaactccc
     2461 tgaaatctgc tatgcttacg tctcagctct tattcatcaa ctcgaagcag ttttttggaa
     2521 gtcatggaaa cgttcctttg tcttttcaaa gatctttcga ccaacgagta aggagtcacc
     2581 attgaaaaat tctaacacat aatgagcaga atcaattttc tgcaattgcg ataagttgat
     2641 acagtaagat tttaatagta aaaagtaagc atacttttcc aactctgtct tcaattgttt
     2701 taaagaagta ttcactaatt tatcttctgt agttgttttg accataactt ggtttttcaa
     2761 acctttgata ctttcaatat ataaaatttc ccgaggatac aggacgagac ttccaccttt
     2821 ttgatcaata aagattttat cgacatttac gatttgctgt tctttccaat tgatctgttc
     2881 tagcacttga cgaatttgtt cagataaatt cctgtctttt ctgatatatc caatcggaag
     2941 gattttccga ttgatgatct ctactgcaaa attcgtataa gcggtgaaaa aaacaatatt
     3001 actatgtgca ttttttttac gtatttgttc ggcgacatca atacctgtga gtgattgctt
     3061 caagtcgata tcgataaaga aaacatcgtg attatcaata gtacccaact ggatcaactg
     3121 attgatttga gagatagaag tgagctgcac gatattctcg atatgatgat tgaccaattc
     3181 tttgatgatc cattcgctgt gaaactggtt atcttctatg ataaaatact ttttcatatg
     3241 caggctccta ttaaaaaaat atgtgtacat tttgaaacaa aacaatggag gaataagatg
     3301 gtcgcaacag tgacacttta tttgaccttt actttgattt tagatttagg tatctattta
     3361 ttcttttcga aacaactgct agtaaaaaac agctttggtt ttatagcttt gatggtggtg
     3421 acacttttat ttcctatccc taaagtgagc tttccttacc tagttggctt attattgatg
     3481 tttctttttt attttactac gaaaaacctg tttatcagct gtttgatcag taatcttttt
     3541 tttgctatca ctggactcag cttttttctg gtttttgatc tgatggatta tttaggaaag
     3601 agacatcttg gaacagcaag tttttttgca ctacttatcg catttatttt ctatctatta
     3661 gtaaaaagta tagacaaaca gacgagattt ctcaacttgc tttttactta tccaactgaa
     3721 cactattttg gaggtatttg tattttatta agctggggcg tgatttactt ggtattggga
     3781 agtgttcact tccgctcatc taattatctg cttctatctc ttttgtcgat agtcatcagt
     3841 tttttttctt tgtttttttc cattatgttg atcagtttcc aagtaaaaga aagacaacat
     3901 caggaatcgc ttcaactgta tcaaataaat gaagaatatt accatcatct agaggaattc
     3961 aaacatgatt ataaaagtct actgttttca ttaaaaatta ctcttcagga aaataaaaaa
     4021 gaaacgttgg aatttttaga aatcttagaa gatcattctg cagctatttt tgaaaaaccg
     4081 caaatacaac agctaacaaa tattgtatcc ccagctgtca ggggtgtctt tttaaaattt
     4141 ctagaaaaag cagaatcgga gaaaatcccg atccaagtag ttattcctgt cgaagtgaaa
     4201 acaatcccga ttgatctggt tgtttttatt cgctgtttat ctatttttat ttctaacgca
     4261 ttcgatcatc gtgtagccga tcagagtccg attacgatca atctgctgga agaaaaagag
     4321 ggattacgtt ttagtatagc gaacaaggca aatccgacga atttgacgct atcggagatg
     4381 gtcaaaagag gaaaaacctc taaaaaaaat ggcgggttag gtctatacag tgcgaaaaaa
     4441 atgttggatg tttacgaaaa tgcagaacta aaaatcgaat tttcaaaaca gaatcactat
     4501 ttttttgtag aaatgtatct ggcatctaga aagagcaaat cagcctactg acttactgtc
     4561 aaaggataag cttgaggaaa gtctacacgg agatagagac aacaacacag catattcaaa
     4621 agaaacagaa gcgtgatgac cgttgtcacc cttctgtttc ttttgctatg tagttaaaca
     4681 aagtagttga cacttccgct acttagtatt agtacgaaag tatacttcat gatactaagt
     4741 agataagaag tgaaaagcgg aacccacgat cgtcaaaatg ctaactgctt tgcttacacc
     4801 agataaaggg aagagcaata tcgcttattt taggcgtgga gaagcaagaa aatccctacg
     4861 atcacacaaa aaatgctgac ccagcagtta agagagttag aacaagatgg cattgtccat
     4921 cgaaaagtct ataaccaagt cccgcctaaa gtagagtact cgctcaccga agaaggaaaa
     4981 tcattaagag agattctagt agcgatgtct gtttggggag aagaacgtat cgaaaaacaa
     5041 aaagcctcag gggaagaagt cacattactg catacacatg gtggctacct aaattactga
     5101 tttctatgac atttatttta aataaaagaa aacaggagtt tttttaaaag catcatctat
     5161 tttttatgta aaaaaatggt atgattaatc aagtaagaaa tgattggaag aaggcaagca
     5221 aatgaatagc atggaaaaag ttaaccagtt tagagatgaa cgtaattggc gacaatttca
     5281 taacgaaaaa gatttggcta tttctatttc tttggaagca tctgaattgt tagaactttt
     5341 tcaatggaaa acgccggaag aagtaaaaga aacacaatta gaacgaatca aagaagaact
     5401 ggcggatgta ttgatctatt catacatgat ggcagacaac cttcagctgg atctagatga
     5461 gatcattgaa gaaaaattga tcaaaaataa tttgaaatat cctgtagaaa aaagcgcagg
     5521 tgtacgaaaa aaatacacag agttttagaa atgtgtcatt cggctgttgg aaagagcaaa
     5581 agaaaaacag taaaatgagt ctggagggag agaaaatgaa aaaaaaagga aaagcaaaaa
     5641 gatggctagt caatatcctc ttgttcctct tgttattagt aggactagct ttgattttca
     5701 atgaacagat caaggattat cttgtcagag agacaggaga taaatatgct atagcgaatg
     5761 taacaaaaga agatctgaaa aagaataacg ataaagatgt cagttttgac tttgatgcgg
     5821 tagaaccaat gacgacagaa ggggtcatga ggtcgcagat gagaggaaca gatctaccag
     5881 tgattgctag tatcgcagtc ccttcagttt caatcaattt accgattttc aaaggcttgg
     5941 ataatacgtc actactttac ggagcaggaa cattatctcc agatcaagaa atgggaaaag
     6001 gaaattatgc cttagcaagc catcgtgcaa cgaaccctga attgttgttt acaccgctgg
     6061 aaaatttaga gatgggtgcc aagatctatt tgacagattt agaaaatgtg tatacataca
     6121 aaacattttt taaagaaaaa gttgctccta cagataccca attactgaat gaagtcgagg
     6181 aaaaagaaat tgtcacacta attacttgtg gcgacatgga cgccgtcacg cgactagttg
     6241 tacaaggaga actggaaagt gttacaccga taaaagatgc gacagatgat atgagatctg
     6301 ctttcaatct agagacaaaa acattttagg atactgggac ataagtcgtt acagattaaa
     6361 aacagccaaa ggatatgaat cgataaggaa aaaccaattt gctgaaaaaa agaggaacgc
     6421 aaagaggtgc atctctgatt tggttgtttt ctagatagac ttgtgttcca gtttttttat
     6481 tttttatatg aaaaggcttg cataaataaa aattcgatgg tatgatgatt ttgaataaga
     6541 aatggattgt tactgtacgg caggcaaaac cagaattcag ctaagaaaca gtaggcgaat
     6601 tctaggtttt tttatttttc ttgagagggc gaagcaaaat gaaaattgat aaaattttga
     6661 ataacaatgt cgtcatttcg aaaaatggat tcggggaaga agtcgtttgt atgggaaaag
     6721 gactagcttt tcaaaaaaaa gattggggac gagatttcgc cagaagcggt ccaaaaagaa
     6781 tttattttaa gagattcttt tgctaaaaac caattccagc agctgatggc tgatattccg
     6841 gcagaggaga tcgaatgggt caaacaagta gtcgaactgg ctgaagataa actaaaagtt
     6901 gaattttcgc ctaatattta tctgacattg accgatcatc ttcattatgc gatcacacga
     6961 gcaaaagaaa atatccaact gcctaatcca ttattatttg aaacaaaaaa attttatccg
     7021 aaagaatatc aagcagcgaa agaggctctt ttgttcgtga aacaaaagac gggtgtggaa
     7081 ctttctgagg atgaagccgg ttttattgcc tttcattttg tgaatagcca acaaggaaac
     7141 gaagacatgc aagtgacgat gaccgctacc acaatggtaa gagatatact gagtatcatc
     7201 agtaaattct tcggcatcgt gttcgatgaa gaatctttga attatcagcg tatcattact
     7261 catctgcagt tttttgccca gcgttatctc aaaggggaag gatctgacga gcaagatgaa
     7321 tttctctacg cattagttca aggaaagtat ccaaaagcgt ttcattgtgt cgaacggatc
     7381 aatgagtatc ttcgacaaac gcaaaaacag gaaatgggga tcgcagagca gatttattta
     7441 acgattcata ttcaaagagt agtaagtgag aaaaaaagca tccaatcata aggattgtta
     7501 ctgtatggca ggcaaaacct ggattgaaaa aataggttca cgaatgtttg tgactgtttt
     7561 tttcaatctg ggtttttatt ttttaaataa aaaagaaaga aggaaaaaac aatggataat
     7621 caagcagttg gtcgtcgtgt atgggaagcg gtaggaggac aaaagaatgt caaaagttta
     7681 gtacattgtg ctacgcggtt gcgattcaga ttaaaagatg aatctttagc agatacgcaa
     7741 aagttaaaag aagacccgga cgtgatccaa gtcgtacaaa gtggcggtca gtatcaagta
     7801 gtgattggca gtaatgtagc agatgtttat caatcgatcg tggatgagga aggtcttgca
     7861 gtttcggagg atggaaaaga agagtccaaa aatattttga atcgtctgat cgatattatc
     7921 tctagtatat ttacaccttt tctaggggcg atggcagccg ccggggtatt gaaaggattc
     7981 ttatcattgg caacggtgat gggctggctg acagctgata gcggtactta tcaaatattg
     8041 tttgctgcag cagatggtgt ctttaccttc ttacctgtca tgcttgcttt tacagcagct
     8101 aaaaagttca aagccaacca gtttttagca gtagcaattg ctatggcact tgtgtatcca
     8161 gctatcacag cagttgctgg tgcgggagaa gctatcagtt tctttgggat cccagtgatt
     8221 ctttcaccat ctggttatac ttcttctgtc ataccaatca ttctagccgt atgggttcaa
     8281 agtaaattag agccattcgt aaaaaaagtg attccgcaat ttctgcaaat gattttagtt
     8341 ccgcttgtcg ttttagtagt gatggttcca ttaacatttc ttgctttagg accaatcggg
     8401 acggttgccg gtaatgcttt aggcggtctc ttcaactcga tttatggatt tagtccaatc
     8461 gtagcaggtc taatcatggg aagtttatgg caagtattcg tgatgttcgg catgcattgg
     8521 ggattcgtac cgatcatgtt tttgaatatc gaacaatatg ggtttgatgt attgatgcca
     8581 atgcttcttc cagccatctt ggcacaaggt ggggctgctt tagctgtagc attgcgaaca
     8641 aaagatacga aacttcgagc attagggatt tcttctacag tgacttcgtt atttggaatc
     8701 actgaaccaa ctgtgtatgg tgtgacatta cctttgaaga aaccattcat tgccgcttgt
     8761 atttctggag gtattggtgg agctattatc ggattttccg gagtaaaagc tttctccagc
     8821 agtttggtca gcttattgac gattccgact ttcattaata cggtggatgg tgtagagtca
     8881 aatgtgacag tagcagtaat agctacagga attgcttttg ttcttgcatt cgtaggtaca
     8941 ttgattttag gatttgacga acaaacacaa gacaatcaat tagaaaacaa acatgcgaat
     9001 gcaggagaac cgattacttc agcacggcat accttaaaaa gtcctttaac gggtaaagta
     9061 ctgccattga gtgaagtacc agaccaagtt ttttcttctg gcgtgatggg aaaaggtatc
     9121 gctattgatc cagaagtagg agaactagtt gcacctgcag acggagagat cacgactatt
     9181 tttccaactg gacatgctgt agggatcaca acgactgacg gagcggagat tttgattcat
     9241 atcgggatgg atacagtaga attaaatggg aatggctttg agatcttagt caaacaaggg
     9301 gatctcgtca aagcaggaga tttattgatt cgttttgaca tcgaagcaat tagagcagct
     9361 ggctatagcg taatcactcc agttgtcatt acgaatactg atgcatttgc cgatatactt
     9421 gaattagacc aaaaagagat tattgcaaac gaagatgttc tggcaattgt aaaataagga
     9481 ggaaatcagg atgcaatcac gtttttcaga aaaattttta tggggtggag caactgctgc
     9541 caaatcaatt agaaggggct tatgatcgag acggaaaagg actatccgtt gcagatgcta
     9601 tgcctggagg taagcagcgc tttgcgatta tcggcagtga agaatttgac tggacgattg
     9661 atcaagaaaa atatatttac ccgaatcatc gaggaatcga tcattacgat cgtttcaaag
     9721 aagatcttgc cttgtttgcg gaaatgggat tcaaatgtta tcgtttttcg attgcctgga
     9781 cacgaatttt tccaaatgga gacgaaggta ctcctaacga agcgggatta gaattttatg
     9841 atcagctgat tgatgagtgc ttaaaatatg atattgaacc tgtgatcacg atttctcatt
     9901 acgaaatgcc tcttcatttg gcaaaagaat acggtggctg gaaaaatcga aaactgatcg
     9961 acttctatga acgatttgct cagacagtat tagagagata cagcagtaaa gtcaaatatt
    10021 ggatgacttt caatgaaatc aattcggcct ttcactttcc agctttaagt caaggattag
    10081 taaaaagcaa tggagcagga gagtaccaaa atattttcca agcatggcat aatcaattcg
    10141 ttgcaagtag caaagccgta aaaatcggcc acgaattgcg ttcggatatc caaatcggct
    10201 gcatgattat ctatgcaaca acttacagca tcgatgccaa tccagtcaat caggcagcaa
    10261 caatgatcca aaaccaagaa ttcaattttt tctgcacgga tgtccaagta cgtggagaat
    10321 accctgcata cacagcgcgt acccataaaa aatatggagt cgatccggaa aaattagagc
    10381 aaacggaaaa agacttccag ttgctaaaag aatatccagt ggactacatc ggatttagtt
    10441 attatatgtc tacggcaatc aatgagactg atccacaagc agcaacttca gaagggaact
    10501 tgctgggagg agtaaaaaat ccgtttcttg aggcaagtga atggggctgg cagatcgatc
    10561 cagaagggct gagaatcgca ttgaatgaat tatacaatcg ttaccagaaa ccattattca
    10621 ttgttgaaaa cggtcttgga gccattgatc atatggaaga ggatggcacg attattgatg
    10681 attatcggat cgattattta cgtcgtcata tcgaagcgat ggctaatgca gtagcagacg
    10741 gtgtagattt gatgggctat acgccttggg gatgtatcga tcttgtcagt gcatcaacag
    10801 gagaaatgag taaacgttac ggctttatct atgtggatct agacgatgaa ggaaatggga
    10861 cactgaatcg atcaaagaaa aaatcttttg attggtataa agaagtaatt gcctcaaatg
    10921 gcgtaaactt gtaattaaag cagctgaatg aaaaagaaca cacttctcac atgtgatttg
    10981 tgttcttttt ttatttttta tgtgctattc ttttagtaat agtaaagcaa agggtgacgt
    11041 tatgaaaagg acacgtgtac tatacttgga agtcgcagat aaaattaaag aagatatttt
    11101 ctcaggaaaa tatccagtcg gttcgatgtt gccgacagaa agtgaattag aagaactgtt
    11161 tcaagtcagc aaaatcactg tccgaaaggc aatcgaactg ctggcatcag atgaatatgt
    11221 cgcaaagaaa agtggtcgtg ggacgacggt tctaagcaat cgtccttaca atcgattatc
    11281 caaagcggca agctttacgc aaatcttgga gaactcccga tatgaagtcc ggaaagaaac
    11341 gctggatttg caattggtcc atataaagaa ggaagatcct ttgttttcct ttttcggtga
    11401 gcaagctgtt tgttttaagc gcttatatta tttgaacaat cagccttata tttattttgt
    11461 tcattatctt ccacaagaaa tgatgcaatt cagcagagaa gaatttggca aagaatcttt
    11521 gtatcgtttg ctgacgaaaa aaggatatac tattgactca ttttctgatg atttctcggc
    11581 agtattttta acagaagaag aacaaggaat tctgaaaaca gacgcacaga tcggcatcaa
    11641 acggatacgg aaatcgtcta cgcaaattgg ggaaatgatt gaatattcgg aggcggtcta
    11701 ccatacggag ctgcatcctt accatattga ttatgaaaca taaataaaaa aagaggttgt
    11761 gaaaaagctg ccctgcatca agtaataaga acagccaaac aaaaatagct tctcatattt
    11821 ttcgtttggt taggcttatt accgcagata cacggctgtt tctggattac catttattct
    11881 ggataagggg gtgtggcacg attttcagaa ggaatctatg aaccaatcac tgtattgatt
    11941 ttagcttcga tggtaacccc attcggcttg acgatcgctt atttcttagg gaaaatcatt
    12001 cgtaaaaata tactcaatcg tcaagaaatc gatacattga agaccgcttt tcctatgggg
    12061 atctgtcaga tcacagaggg atgtttccct atcgtattga acgacttggc acgcaatgtc
    12121 atagcaacgg gagtcggtgg gacagtaggt ggcggattaa gcatgttttg gggcgcagat
    12181 agccgtattc cggcatcggg aatgtttgca gtcgctacga tgaccagacc atgggcattc
    12241 attggtgcat tgttagctgg ttcttttgtc acaggaataa ccattttatt attgaaaaaa
    12301 ccagtagatc cgaatgcaga aatcatccaa gaagaaaaag aggaagaaga catatcttgg
    12361 gatgatttga caattagtta ggagaggcag aatggattac aagaaaaaag tacaatagat
    12421 gtaccttgag acaggaatgg tatgaaagaa tcagagttag aaagaatcga atatacagat
    12481 tttggtttag gagcgatcga aactgtccag agcatcggca ccctccttga aatgacgatg
    12541 aaggaaaaat gagaaccttt cgttgtcgaa agggtctggt ataccttatg tcgaaggaaa
    12601 ggaaacaaaa aaactttcct gtactattcc aaaaaggaaa gaaagttatt atacagtaaa
    12661 aaaagaaatt attcttcatg ctagagatca gtacacgttc gagcccaata tcaaacacta
    12721 gttccaggca ggcgcaacag gtgcggttat cactgaattt tcttccagca gtgacgattc
    12781 aagtgatatt tttacaaatc cagctattta tcgttaacaa aaagattttt aggagaagct
    12841 gatgaacaaa aatgatcaaa ttttgatcgt ttagttcgtc ggctttttta tttagagaaa
    12901 catcatttat cagtgaaaca taacacgaga acaaaatgat tttttcgtta ataaaagaaa
    12961 caagtatttg ttgtttaaaa taatacacgt tattggcata taggacgaaa tcccagtatc
    13021 ttctataagt aagtcatttc atatcgatga aaacacgtta tttatttttg ttttatctat
    13081 aaaatggctg aaaaatgatt tttttctaaa tactatatat agtggcgtct atcctatata
    13141 ccactaaaaa actacaaaat ctagtctttt attttaaaaa aacacgtgta gaatgaagat
    13201 agacttttga gttagggagt gtttttttat gaaacttact gttttttgcg gttcccgttt
    13261 tggtaataaa gaaagttaca aatttattgc gcaaacgtta ggaaaataca tggcacaaga
    13321 agaaatcgaa ctggtttacg gtggttcata ctccgggatt atgggagtga ttagtaaaac
    13381 agtactggaa aataacggaa aagtcacagg tatctatccg aatgggcttt ttgaaactga
    13441 attgcctgga aaagatgtta ctacatttat tcctacagaa acgatcgatg aaagaaaggt
    13501 attattattt gaaaagggag atgctgtcct cgttttccct ggaggtctag gtacattgga
    13561 ggaattctca caacttcttt cttggatagc aatcggtctg acgcccgaca agccaatcgg
    13621 aatattgaat attggcggtt attacagcgg cttgcaacaa ttattagaaa cttttgcaaa
    13681 agaggatttt atggataaaa aatggttgga tcaagtaatc ttttccaaca atccattgga
    13741 actggtcaat gaattacgag cagtatctat taaaaatcag ttattattga aggaggcaaa
    13801 ataatgagtc aaatatattt agcaggacca tttttttcag aggagcaaat cgatcgagta
    13861 agtcgtatcg aaaaagcgtt ggaggaaaac aaaacagtca caagtttcta ctctccacgt
    13921 catcaccaag aaagcaatta tgaactattc agcgctggat gggcgcagga agtatacgaa
    13981 aaagatatgg aagaactgac aaatgcagaa tttgttgttg ctatccttga ctttgagcat
    14041 caaacaatcg atccaggaac ggcttacgaa ttaggtgtgg caactatgtt gaaaaaaccg
    14101 atgatcattg tacaagaaga gacggtacct acgaacttga tgattacaca aagtctccat
    14161 acgtatttaa aatcagacca agctgtacgt gaatatgatt ttgaaacatt gcctgttgaa
    14221 acttacgtag gcgagtactt atagaagagg aagggttgta tgtcagtgat tttgatttca
    14281 ggaacgattg gtgcaggtaa gagcagtttg acggatatgc ttgcaaaaga gattgattct
    14341 aaaccatttt atgaaaatgt cgaagataac gaagtattgc cgctctttta ttcaaatcct
    14401 gagcagtacg cttttttatt gcaaatcttc tttttgaaca agcgattttt agcaatgaaa
    14461 aatgctttag tgaacgatga caatgtgcta gaccgatcca tctatgaaga tagcctgttg
    14521 ttccatctaa acgctgattt aggtcgggta acggatatcg aagtacagca gtacgatagc
    14581 ttattagata cgatgctaaa cgagttagat gatgttgctc caaaaaaacg gcctgatttg
    14641 atggtccata tcaaagtttc tttggacacg atgctagaac gtatcaaaaa acgtgggcgt
    14701 gactatgaac agctagaaag cgatgagacg ttatatacct attatgaaac gttgaacacc
    14761 cgctataatc aatggtatga agattttgat gtatgtccta aaatacaagt ggatggggat
    14821 aaattcgatt ttgtagaaaa tccagaagat gcaaaaaagg tgatccgtca gatccaagaa
    14881 aaattagctg aattggaagg aaagcctgct ggaaaatatt ttacggataa ccagcatgca
    14941 aaaggtcaag aattaggcta aaaataaaaa accaaacgac gggaaagaaa aatt
//
LOCUS       DADQDV010000070        14960 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.072, whole genome shotgun sequence.
ACCESSION   DADQDV010000070 DADQDV010000000
VERSION     DADQDV010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14960)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14960)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14960
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.072"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            4..2376
                     /locus_tag="J8S10_002330"
     CDS             4..2376
                     /locus_tag="J8S10_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630903.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQKMTNGQ
                     PMNDKRNGRSWFNQQERIENKVQSLREEIKQQEEYVEKLERQEELKEMGYNKYGGLDM
                     TIDNIPRIKEEIERFEKGESAFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     RPTDSMKEKENDHFYRVEFNENDPEKGLKSYGGEIVTFELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQSVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTLETPENKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2437..3897
                     /locus_tag="J8S10_002331"
     CDS             2437..3897
                     /locus_tag="J8S10_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HAZ9630904.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDPKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKYERQNF
                     LVRDDRLDHAVAFLWKDPQTKETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQIKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKII
                     YEEVAKEEKVTPEAIMAIHKTENNLQLTNQLVSAHKVNAFFGQQLSVNDSIEAINLKD
                     ICREVAKELKVCERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFVPE
                     VKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            3908..6112
                     /gene="topB"
                     /locus_tag="J8S10_002332"
     CDS             3908..6112
                     /gene="topB"
                     /locus_tag="J8S10_002332"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAZ9630905.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFPGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQVGADQGKTFKRLWINSLEKEAIYQGFQQLRDAKETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FKKEPYFEGKSEVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGMIRQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLRAEEISTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTEATYES
                     LTPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIGKVPIDLGWKKLFGK
                     ESDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGVLLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSIDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNSRTSQPVKGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNFKKRTRRTTK"
     gene            6352..6945
                     /locus_tag="J8S10_002333"
     CDS             6352..6945
                     /locus_tag="J8S10_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection protein"
                     /protein_id="HAZ9630906.1"
                     /translation="MQEKLKELLAIRDGNLSMKEARKLGIAATTVQRLVNQGKLIKVD
                     RGYYVEDGHGIDDLFWLQQRFSRGIFSHETTLDIYQLSTNMPKFIHLTFPHGYNVDRS
                     ITKEQQLQFHFVKKEVYELGKVEGTSFQGNPITMYDKERTLCDIWNPRYEIEYEMKLE
                     ALKEYMEDPLRDPSKLRDYMTKLHVEKEMKYHMQSLY"
     gene            6958..7857
                     /locus_tag="J8S10_002334"
     CDS             6958..7857
                     /locus_tag="J8S10_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HAZ9630907.1"
                     /translation="MTPTQFAAKTRNLAKRTGLNAQLVQRHFMMDRLIEQISESKYKN
                     DFILKGGFLLGSKYGIDRRTTIDIDTTFRNSKLTEEKLKSIFNDLTRKPTKEGIVFSI
                     QGMKETREADFYPGFQIKLVANLEKVRVPFKMDVTTGDSIYPEVDTHYHQLMFEDKKV
                     EIPAYPTAQIIAEKLSATFSFGTDNSRAKDYYDLFTIPKLENIDTKELYKSVRNTFTK
                     RGDTKPLSFYYEREMDKIIGNDYLEKQWEKYRSVNTFANSISFTDTVNEIDHLMKSVI
                     KIENQERKRQFKRSQQMNQEMER"
     gene            7860..8357
                     /gene="ssb"
                     /locus_tag="J8S10_002335"
     CDS             7860..8357
                     /gene="ssb"
                     /locus_tag="J8S10_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAZ9630908.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMVTLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSSTSPSTTTFEQRDTATPNNNGLNALQNPFGNPFGGQSIDISD
                     DDLPF"
     gene            8723..8983
                     /locus_tag="J8S10_002336"
     CDS             8723..8983
                     /locus_tag="J8S10_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630909.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
     gene            9428..9634
                     /locus_tag="J8S10_002337"
     CDS             9428..9634
                     /locus_tag="J8S10_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HAZ9630910.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGQRAKCIKSYRLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            9682..9885
                     /locus_tag="J8S10_002338"
     CDS             9682..9885
                     /locus_tag="J8S10_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630911.1"
                     /translation="MVDKEVISEKVAEALLIPRYWTIETPLVEDAPTMLFEDLVKIAG
                     YELHYQENMETYENEYWLTKLEN"
     gene            9901..10338
                     /locus_tag="J8S10_002339"
     CDS             9901..10338
                     /locus_tag="J8S10_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630912.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKERLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNAKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYGKFVETKKAKTVSSEWLDYFENINKYGAYYTMKKEDNENE"
     gene            10331..11038
                     /locus_tag="J8S10_002340"
     CDS             10331..11038
                     /locus_tag="J8S10_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630913.1"
                     /translation="MNKVIYQLTTEDVSHFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYLESETSQTKVTVSNNYLDVYKHRPETVKKGTELLRLETEKYIMNVYLERS
                     ELVENFVSCTICRKHYYSESEYYSIFESMELMEEEMEELNSKNATIDDYYLVFTRFLT
                     CGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKRQ"
     gene            11418..11597
                     /locus_tag="J8S10_002341"
     CDS             11418..11597
                     /locus_tag="J8S10_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630914.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDIPALKK"
     gene            11922..12185
                     /locus_tag="J8S10_002342"
     CDS             11922..12185
                     /locus_tag="J8S10_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HAZ9630915.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
     gene            12179..12529
                     /locus_tag="J8S10_002343"
     CDS             12179..12529
                     /locus_tag="J8S10_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAZ9630916.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
     gene            complement(12553..13167)
                     /locus_tag="J8S10_002344"
     CDS             complement(12553..13167)
                     /locus_tag="J8S10_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAZ9630917.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLKKGVAIAKIAKDYNVTRQTVYRIKKDSMVNHE"
     gene            13481..13903
                     /locus_tag="J8S10_002345"
     CDS             13481..13903
                     /locus_tag="J8S10_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630918.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            13913..14116
                     /locus_tag="J8S10_002346"
     CDS             13913..14116
                     /locus_tag="J8S10_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630919.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            14327..14911
                     /locus_tag="J8S10_002347"
     CDS             14327..14911
                     /locus_tag="J8S10_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAZ9630920.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
BASE COUNT         5512 a         2429 c         3034 g         3985 t
ORIGIN      
        1 aacatggcag aagaaaaaga accactagac aatagtcgtt tgggaaaatc caaaagaaaa
       61 ctagtacgat tgcaaaatga attaaacgaa caaattgaaa agatgtttga acaccaaaaa
      121 atgacgaacg gtcaaccaat gaacgacaag aggaatggcc gttcatggtt taaccagcaa
      181 gaacgaatcg aaaataaagt ccaaagtctg agagaagaga tcaagcaaca agaagaatac
      241 gtggaaaagc ttgaaagaca agaagagcta aaggaaatgg gctataacaa gtacggcgga
      301 ctggatatga cgatcgataa tattccaaga atcaaagaag aaatcgaacg ctttgaaaaa
      361 ggtgaatcgg ctttttcagc cgccacgatc cgaaaatacc aacggaagtt ggaaacatta
      421 gaacagctga aagaaaaatc agaaaaagga aaagaaaata tcctccctga agtacaagcg
      481 atcattgaca gcggacgagt gacgcaatgg aaaaaaaatc caaccattta ttttttgaaa
      541 ggctatcgaa aagttgcttt agaactgaat gaaaacgggg gatttgagga atcaaaaaaa
      601 taccaagcca cgtcggaaga ggaaaaagca gctgttcgtg aattacttga agaggctaga
      661 ccaactgatt ctatgaagga gaaagaaaac gatcatttct atcgagtaga attcaacgaa
      721 aatgatccag aaaaaggatt gaaaagttat ggtggggaga tcgtaacatt cgaattgatc
      781 gatcaactca aaacattgga taaccaatac gccgcagaag caggttatta taaattctat
      841 tttgaggaag tgaagaacgg agaagtagtc gatcagatcc gaatggatct aggggatggc
      901 gtcaacagta atcaaccaat ctatttagag ttagcaaaat tgtgcgaaca agtacctgag
      961 aaggaacaaa aacaatcggt caaaaatgaa cctgtttcga aagaacaaat gcagtcgaaa
     1021 gaaacaaaaa caaaacaaaa gggctatcaa aaacgaacgg cagaagagat taaacaagaa
     1081 gttaaatccc tttcgcaaca ggcactggat gcggtgaaaa agcataccca ttctcctgaa
     1141 gacgtcaaag aacttttgaa ctttatgtct cgttttccag aacgatcctt tagaaatcaa
     1201 ttattgattg aggaacaatt tccaggtgca acggcttgtt taggtcgtgc cgcgttgaaa
     1261 aaagaaggaa tctatatcaa aaaaggggaa caagggaaca agatctttgt cagaaaaacg
     1321 gtcaaagggt tttatgagaa aggacgtggc tttgttcgag aaacagaagc tacaccagaa
     1381 gataaaaaac gaatcgaaag tggtcaaatc gaagtgatca aaaaacctta ctatacgatt
     1441 gaaaaagtgt ttgatatcac acaaacacag ttaaaacctg aagactatcc gaaaatcttt
     1501 ccgaaccgtg tctttgattt tcaattggat aaaaaaggac agtcagaact tcaagctggg
     1561 attcaagcgg tagccaacaa tattggaata caaattcgag atatgacaga aagtgaagtc
     1621 tatcaaagag aattaggaca agcacgtggg gcgtatgttc gtaacgaatt tactggcgaa
     1681 gaagaaatcg tcatgaatac tcgaaatact cctacgcagc atttagctac aagtattcat
     1741 gaattagccc atgcaagaat gcacaaattt tcagaattag ataccgcaac taaagaattg
     1801 caggcagaaa tgacttctta tattgtgtgc aaacattttg gaatggacac gtcggagaaa
     1861 gctattcctt atattgcagc atggacgaag aatggtcaga cgttggatga taaggaagct
     1921 gcggaacgtg ggaaaatcat gaatgatgtc agccgtgtcg caaatgaatt cattcaaacc
     1981 atttctaatg aaatcaatca atacagagaa agagaaccag agatccaacc agcagaagtg
     2041 aagcaggagc ataaaaatac tttagaaacg ccagagaata agaatattgt gcccgttggt
     2101 tcactttgga tcgacaagaa agacgggaaa gtaatggaag aagatacggg tcgaacgtta
     2161 catttgaagg atgcggcgtt tattgaagat ccgcagcata atcaagtaat tttaaaagga
     2221 aaaagttatg gaaaagagat ccaaacggcg ttaccttcag aagaatttgc gctaggaaat
     2281 ccattccgat tttcacttga gacagtgtca gaagtggcaa aacgaaaaaa tgaaatctat
     2341 tatgaacaac aattgtcaca aaaagaacgt gtataaaaca agtaaaaaag actatctgaa
     2401 aaacggatag tcttttttct tttgggaggt tttaaaatga ccgagaaaaa aatgagtctt
     2461 attgatcgat gtaaacagat cgatatagtg gattttgctc gaaacaatgg aatggctgta
     2521 gtcaataaag gacgagatta tcgcttagaa gaccatgatt catttgtttt tgatcgaaga
     2581 aaacaacgtt tttattggaa cagtcaaaat attagtggcg acattattga attagctaaa
     2641 ctttttttca tagacaaaga gatccaagac cctaagcaac aatttaaagc agccactgat
     2701 tttattctaa agaatgaaga caaaacagaa cgagtggaaa atcttcattt tgaaacagaa
     2761 aagtacaaag atcaccccgt tgattatcaa ccactcacag aaaaaggaag gaattatctg
     2821 aaggaagaac gaaaactacc agagtggctg attgattatg cagaaaaaga agggttgatt
     2881 gccgaactaa agccaaaata tgaacggcaa aatttcttag ttcgagacga tcgtttagat
     2941 catgcggtcg cctttttatg gaaagatcca cagacaaaag agacagtagg ggcgagttat
     3001 caaggaacgt tcattgatta tgaacgtttt ggtgagagag gcacatataa gcatatagat
     3061 aaaaattcga cagcgaatca tggctttaac ctaaagatcg gtgaccctaa gcagataaaa
     3121 ttttttgaga gtagtattga tttacttagc tatgctgcac tgaatcgtga tcagttaaac
     3181 gatacgtggt tagtctctat ggaagggtta aaacaccatg tgatcagtca ttattttggt
     3241 gaggcagtat ctgaattgag aaagaaacaa gcctttcctc aatccatcga gatttgtgtg
     3301 gataatgacc gtgcaggaca tattttctac gaaaaagaac aattaatggg cgcagtcgat
     3361 ccatttacga atcagaaagt acgttgtgaa cgaggaatcg ctaatgattg gcaagtgcca
     3421 aaagaataca aaatcattta tgaagaagtc gcaaaagaag aaaaggtcac accagaagct
     3481 attatggcca tacacaagac agaaaacaat ctgcaattaa cgaaccaact ggtttccgct
     3541 cacaaagtaa atgcgttttt tggccagcag ctttctgtta acgattcaat agaagccatt
     3601 aatttgaaag atatttgtag agaagtcgca aaagaattaa aagtttgtga acgcgtggat
     3661 ggtacgtacg attttgatcg tttttatcaa gaaaaagggg atattaatgc gcagattctt
     3721 ttctcttata aagcagaaca atactacaaa ggctataaaa atcatgaaca tgaatttgta
     3781 cctgaagtaa aaaaggactg gaacgatcaa ttgaagcatg agatccagca acaagaaatc
     3841 agaaagcaaa aacgtgccat gttgtttcaa caaggcagac aacaagaaag ggagtgaaat
     3901 cgtcatgatg aaaaccgtta ttttagcaga aaagccgtca caagcgaaag cttatgccga
     3961 tagcttctct aaagccactc gaaaagacgg gtattttgaa atccaagatc gattgtttcc
     4021 tggtgaaact gtgatcacgt atggttttgg tcatttagtc gaattagatt cgcccgatat
     4081 gtacgatgaa aattggaaac aatggtcatt agaacatttg cctattttcc ctacacatta
     4141 tcactatcat gttcctaaag ataagaaaaa gcaattcaag gtggtgaaac agcaacttca
     4201 atcggccgac accattatta ttgcgacaga tagcgatcgt gaaggggaac tgatcgcttg
     4261 gacgatcatt caacaagtag gcgccgatca aggaaaaacc tttaaaagac tttggatcaa
     4321 ctccttagaa aaagaagcca tttatcaggg attccagcag ttacgagacg caaaagagac
     4381 ctatccaaaa tttgaagaag cacaagcacg tcagatcgcc gattggttaa ttgggatgaa
     4441 cggtagccca ctgtatagtt tactcttgca gcaaaaaggc ataccaggaa gcttttcctt
     4501 aggcagagtc caaaccccaa cgctttacat gatttatcaa ttgcaggaaa agattagaaa
     4561 tttcaagaaa gaaccttatt ttgaaggaaa atccgaagta atcgctcaaa atggcgcatt
     4621 tgatgcgaag cttgatccga atgaaaccca agcgacgcaa gaagcatttg aagattattt
     4681 aaaagaaaag ggggttcaat tgggaaaaca gccaggcatg attcgccaag ttgaaaccga
     4741 gaaaaaaagc gcggcaagtc cacgtctttt ttctctatcc agccttcagt ctaaaatgaa
     4801 tcagctcatg aaagctagtg ccaaagacac tttggaagcc atgcaaggct tgtatgaagg
     4861 gaaatatcta agctatccgc gaacggatac cccttacatt acggaagggg aatatgcgta
     4921 tctgttggat cacttagacg aatacaagca ttttttgagg gctgaagaaa tttcgactcc
     4981 tattcataca ccgaatagta ggtacgtgaa caacaagaaa gtccaggaac attacgcaat
     5041 cattcctaca aaaacagtta tgacagaagc gacgtatgaa agtctgacac ctttacaaca
     5101 agcgatttac gagcaagttt taaaaacgac agtggcgatg tttgcggaaa aatataccta
     5161 tgaagaaaca acgatcttga cgcaagtcca gcagcttcag ttaaaggcaa tcggaaaagt
     5221 accgatagat ctaggttgga agaagttatt tggcaaagag agcgacggaa aagagaagga
     5281 agaagagccg ctacttccta aagtgacaaa aggagaaatg gtgacggtag atctacaagt
     5341 ccttgaaaaa gaaaccaagc caccacaacc ttataccgaa ggtacgttga tcactgcgat
     5401 gaaaacagct gggaaaaccg tggatagtga agaagcgcaa tccatattga aagaagtgga
     5461 aggaatcggt acagaagcga cacgggcgaa tattattgaa accttgaaac aaaaggaata
     5521 tatcaaggta gagaaaaata agcttgtggt gacgaataaa ggggttttgc tttgccaagc
     5581 tgtggaaaaa gagccgctgc ttacgagtgc cgaaatgacc gccaaatggg aaagctactt
     5641 gttaaagatt ggagaacgaa aaggaacaca aaccactttt ctagccaata tccaaaagtt
     5701 tgtctctcac ttattggaag tcgtcccagg acaaatccaa tccattgatt ttggatcgac
     5761 gttacaagaa gtgaaagcag ccagtgaaaa gcaagaagcc gcgcgtcatt taggaatttg
     5821 tccaaaatgc caggaacaag aagtcttact ctatcaaaag gtggcagctt gtacgtctga
     5881 agcctgtgat tttaaattat ggacaacgat tgccaaaaag aaactcacag cgacacagct
     5941 gaaggagatt attcaaaata gccgaacaag ccaaccagtg aaagggttaa aaggtcagaa
     6001 gggttcgttt gaagcaacga ttgttttaaa agaagacttc actacaggct ttgaattttc
     6061 tgaaaagaaa aaaacgaact tcaagaaaag aacacgacgc acgacaaaat aatggagggt
     6121 taatcttatg cgtaatacaa cacacaaaca acaagaaatc gaaaatcaaa aagccaaaat
     6181 tcgttcagaa caagagaaat tacgtgccag taaaagaaga cttcagcaat taaagaacca
     6241 gcaacggatt caaaaagaaa tcgaattaga tcgatagaca ttaaccttgt tacaaataca
     6301 ctatcatgat atatttaatg tagtgtattt gtaacaaaag gggggaagta aatgcaagag
     6361 aaactgaaag aattgttggc tattcgcgat ggaaatttat ctatgaagga agccagaaaa
     6421 ttaggaatcg cagcaaccac tgtacaaaga ttggtgaatc aaggaaaatt gatcaaagtt
     6481 gatcgtggtt attatgtaga ggatggtcat ggaatagatg atttattttg gcttcagcaa
     6541 cgtttttcca ggggaatctt ctctcatgaa acgactttag atatttacca gctttctacg
     6601 aatatgccga aattcattca cttaactttt ccccatggat ataacgttga tcgttcaatt
     6661 acaaaagagc agcagttaca atttcatttc gtgaagaaag aagtttatga actaggaaaa
     6721 gtagagggaa cttcctttca aggaaatcct attactatgt atgataaaga gcgtacactt
     6781 tgtgatattt ggaatccgag atatgaaatt gaatatgaaa tgaaattaga agcattaaaa
     6841 gagtacatgg aagacccatt gagagatcca agtaaattaa gagattacat gacaaaacta
     6901 catgtagaaa aagaaatgaa ataccacatg caaagcttat attgatggag gaaaaagatg
     6961 acaccgacac aatttgcagc aaaaacaaga aatttagcaa agaggacagg attaaatgca
     7021 cagttagtac aacggcattt tatgatggat cgtttaattg aacaaatttc tgaatctaag
     7081 tataaaaatg atttcatttt gaaaggtggc tttttattag gatcaaaata tggaatcgat
     7141 agaaggacga caattgatat cgacacgaca tttagaaata gcaaattaac tgaagaaaaa
     7201 ttgaagagta tttttaatga tttaactagg aaacccacga aagaaggtat tgttttctct
     7261 attcaaggaa tgaaggaaac aagagaagcc gatttttatc ctggatttca aattaaattg
     7321 gtggctaatt tagagaaagt acgtgtgcca tttaaaatgg acgtgacaac aggagattct
     7381 atttatcctg aagtagatac acactatcac caattaatgt ttgaagataa aaaggtggag
     7441 attccagctt atccaacagc acaaattatt gcagaaaagc taagtgctac gttcagcttt
     7501 ggcacagata attcgagagc aaaagattac tacgacttat ttaccattcc gaaactagaa
     7561 aatatcgata cgaaagagtt atacaaaagt gttcgaaata catttacaaa acgtggggat
     7621 acaaaaccgt tgtcctttta ttatgaaaga gaaatggata agatcatagg aaatgactat
     7681 ttggaaaagc agtgggaaaa atatcgctca gttaacacgt ttgcgaattc catttcattt
     7741 acagatacag tcaacgaaat tgatcaccta atgaaaagtg tgatcaaaat tgaaaatcaa
     7801 gaaagaaaac ggcagtttaa aagatcacaa caaatgaatc aagaaatgga gagataaaga
     7861 tgatcaataa tgtaacttta gtaggacgct taaccaaaga tccagattta cgttataccg
     7921 cgagtggtac tgcagtagcg acttttaccc tagctgtcaa ccgaaatttc acgaatcaaa
     7981 acggcaatcg agaagctgat tttattaact gtgtgatttg gcgcaaacca gcagaaacaa
     8041 tggtgacatt agctaaaaaa ggtagcttga ttggtgtagt tgggcggatt caaacgcgga
     8101 cttatgacaa ccagcaagga caacgtgtgt atgtgacaga agttgtggcc gataatttcc
     8161 aactattaga aagcaaagca gcgacagaaa gccgtgcgca cgctgatcaa tcgtccacca
     8221 gtccaagcac caccactttt gaacaacggg atacagcgac gcctaataac aatggattga
     8281 acgctttaca gaatccattt gggaatccat ttggtggaca atcaatcgat attagcgatg
     8341 atgatctacc gttctaagta gcattttcta ttggttgcat ttgctacggt ttatgttata
     8401 atttagtcaa caaaaagaat tttcaatcta taaccaaaaa ccactagctg gcgggctagt
     8461 ggttttcttt tacgtttcta ttataagaat taacgggtag gcttactgtc tttcttggca
     8521 aatttacaat caagccattt gcagatatag tgcgcggcta cttctgccat gattgcaaaa
     8581 acaaaatcaa aaagaatttt caaacctata acctcctccc cttgccagat taggccgggg
     8641 tagcagacag caagactatt atagcataat tgaaatatcc aaatgattgg atttttgcta
     8701 taattttagc gaggtgattg tgatgaacaa atatgttggt ttgcttgata aaatccgagt
     8761 aataaaaacg caaccgttat tggttcgctt tactttacaa acgattcatg aatcgattaa
     8821 ttgtgtagtt gcagatattg aaattatcga taaattgcta attatggatg atggaaaata
     8881 caatattgcc gtcacaggtc acttcaataa acgaaatcag ctagttattg ctagcatgta
     8941 tgttagaaat cccgatcatt ttacgcgatc gatgggcata taaaaaaaga agagttgcaa
     9001 tcctaatgta ggactgcagc tctttttgtt ttacatagaa acaagaaaaa tgaaaaggcc
     9061 tttttaggaa ggcgcgagcg ccttctcaat tgaaaaacct ctctcactcc aaccgccacc
     9121 gccgttcgag aagaaaggaa gtgaacgttg cacgttcact aagataaagg gtcttgcaaa
     9181 gcaagacaaa atagaaaaaa cttcctctca ccaaaaggtt cgttcctgtt cgttatctct
     9241 ttattgattt gccagaccgg caacaagttg ccttttatca ccaaaaagcg acaaggacaa
     9301 gggtaaatgg cacgctgcgc gcccttgtcc ttgtcgcttt tcgttgattc attctggcca
     9361 acaaatcaat aaagaaagaa ctaacgaaag gaagtaaaac ctttcctaag aggaggcaga
     9421 atcaatcatg cgaaagaaat ttgattattg gggtgttccc ttcagcgaat tattcccaaa
     9481 ctatcatgca ccacatactg tcgaatgcga ttgtggacaa agagcgaaat gtatcaaaag
     9541 ctatcgtttg tatcaatgtc caacatgcgg aaaaaaatac accttgtctt atggcgatta
     9601 tattttgatt gatgagaaag gaaagaaacg ctgatgaaaa cataacataa attattgact
     9661 gtaaaagaag tcgttcaaat tttggtggac aaagaagtca tttctgaaaa agtagcagaa
     9721 gctttactta ttccgcggta ctggacgata gaaacccctt tagtagagga tgcaccgact
     9781 atgctatttg aagacctagt gaagattgca ggatatgaac tgcattatca agaaaacatg
     9841 gaaacttatg aaaacgaata ttggttaacc aaattagaga actaaaaagg agaaaaaaat
     9901 atggctcaaa attactatga cgaatttgtc aaattacctt tggataaaat ggcacaaaaa
     9961 atggaggata tgacattcct ataccatgag acacgtgttc caaaaaaaca ttataaggaa
    10021 agattgtcgg tagctgtgga agaaatgatt gaatcaggtg tcgaaatgaa tctcattgcg
    10081 acgtactatc gaacactgga agaactgaaa aaacaaaatg caaaatggtt tttccaagcc
    10141 ttactatgct tggaagtagg tgtcaaacca agcactatta aaccttctga atatcaagct
    10201 ttagaactaa cgtatgggaa atttgtcgaa acgaaaaaag ccaagactgt ttcaagtgaa
    10261 tggttagatt attttgaaaa tatcaataag tatggcgcct attacaccat gaaaaaggag
    10321 gacaacgaaa atgaataagg tgatttatca actaacaacg gaagatgtgt cacacttttt
    10381 aacaaacaaa gaacatttga atgaagtaat cagacggatt caaaaagact ttagttgtat
    10441 ggaagaaatg aagtacttta ttcaaagagt cgaagaacaa ttgtatttgg aaagtgaaac
    10501 gagtcaaacg aaggtcacag tcagcaataa ttatttagac gtgtataaac atcgtcctga
    10561 aacggtaaaa aaaggaacgg agcttctacg actagaaaca gaaaaataca tcatgaatgt
    10621 ttacctagaa aggagtgaac tggtcgaaaa ctttgtcagc tgcacgattt gcaggaaaca
    10681 ctattactca gaatcagaat attattcaat ttttgagagc atggaattaa tggaagaaga
    10741 aatggaagag ctaaacagca aaaatgcgac gatagacgat tattatcttg tatttactag
    10801 atttttgacg tgtggaacgg aatctatcgt gttaatggga atggattatg aactcgctgt
    10861 acccgaagca tttttgaggg aatatgtaga agaagtagat aacccaggcg acgactggta
    10921 cacgacttta actgattttt tagataccta cacttacgac gatacagaag aaatccaaaa
    10981 tgaacttgac cgtaaacgaa tgccatatca acgatttgaa aggaaaaaaa ggcaataatc
    11041 atttataccg aaaagtgaga atgtgtgaaa taagaacaaa aaccttgaaa ttaagggaat
    11101 ggttcttatt tcgcaccaat cgctccaacc gcccccgccg cttaggtggt gcgaaataag
    11161 cgggcaaagc ccgataacct aagagaaaga aggagatcca tatgaataaa atcattcctc
    11221 tgttgttcgt actgtgtatt ggcgagatac ttatgcgtca tggtgcagct gtacatttaa
    11281 acttcgtagt attcttagga atactagtat tttgtttgat tttttggcgc tttgtgttag
    11341 cccttgtgag tctactattc aagttgattg cagccatatt tttcataggg ttatttcgat
    11401 gaaaggagag agtactaatg ccaattgcaa taggaaataa acggttaccc gtgacattag
    11461 atgaaaagag acaaaaagaa ttgcagcaac taaagcagaa gtacggaaaa agtgaatcta
    11521 agattatgtg tattgcgtta gatctattga tcgcgcaaga aaaagcagga tttgatatac
    11581 cagcactaaa aaagtgacgt cacttttcat ttgaagaaac aaaagtgata gcacttaatt
    11641 gttcctacta tttagaatat tttctatgtc ctttttattc cattttgtat caataactat
    11701 gaaatcttta aagtatccag atcaattttt ttcttacctg attctaaaga ttttgttttc
    11761 ttaaacatat tatgatttcc tttcgactat tttcatataa atgttaacat agtttatgga
    11821 ttcatggaat gttaatctaa tttaatagaa aaggataatt aagtatatac gttttttctt
    11881 atgtatgtta tactatgtat atacagaaag aggtgtctac tatggaaatg ttacctataa
    11941 aaaaatgggg aaatagtaat ggccttagat tgccaaagta tattatggaa tatcttggaa
    12001 ttcatacaga agacaaagtg aagataatac aagaagaagt aaacggtcag aagcggctaa
    12061 ttatcgaagc ggctaatata gaaaatgaat taacaattga acagttattt gaaaattaca
    12121 ctgatgaaag aaatcatgtg acgattcaaa atttaggtga agcagtaggt aatgaaaaat
    12181 ggtgagaaaa cctagacaag gcgatattct attattgaat acagcacctc gatctggaca
    12241 cgaacagaca ggtaaaagac cttatattgt tttaagtcat gatattattg cggattatag
    12301 taacgttgtt acagttgctc caatttctag tacaactaga aactatccgc tatatgtaaa
    12361 tataaactca gaatatgaaa tgaagacaac aggaaaagta ttattagatc aactaacgac
    12421 aattgattat gaagccagag agtgtatttt tttggaaaaa gcgcatgata gtttagttga
    12481 ggagttattg atgaaagtta gaacagtttt tcaaaaagta agcaaataaa atagaaacag
    12541 cagcatgatc aactattcgt gattgaccat gctgtctttt tttattctat atacggtttg
    12601 tctcgtaaca ttgtagtctt ttgcaatctt agcgatcgca acaccttttt ttagatcctc
    12661 aacgatgttt ttataaacaa gacgacgttg gggatctttt gcattggcac tgtatagctt
    12721 aggacgtcct ttataaacac cgttcgcttt tgcaatctta atgccttgtg cctgacgtcg
    12781 tttagattcg gtacgttctt gttcagcgat catggccaaa atttgaatga tcaaatcttt
    12841 aatgaattta tccaggagag gattgccaat tgcttcggcc atgatcggta gacttgtgat
    12901 gatcagctgc acatttttct tcttcaagta attgactgaa gcgatgatct cgtcgtaatt
    12961 tcttccaagt cgatcaatag cttccacaat aaaaatatct tgatctcgga cgaaatccag
    13021 tgcttcttga aaaacaggtc gatgagtaat cgttgcgcca gattgtttct caatgaaaat
    13081 tctctctgca ccgaattttt tcatttcttc aatctgccgt tgttcatttt gatcgatgga
    13141 tgagacacgt atgtatgcaa ctctcaaaat ttttacctac tttctgcaac tatttaaaaa
    13201 acaccctaat catacacgag aaaaccagat ttttcaatgt cgcggtcgtg tctagttagg
    13261 gtatacctta tatagacaaa aactaatgat ggaggaaata gtatgtgtca cttttctttt
    13321 taaatggcaa tattttttgt aaataaatgt caatcaagaa aatttaaacg attatgacat
    13381 taaaaatata ttttatgaat tttctagtat ataacttgat ttatctgtta agatttatta
    13441 agaaaacgtt ttcttatttt tgatttcgag gtgatagaca atgaaaaata agtttatttt
    13501 atctttaggt attttaacta ttggaattag tgtaactgga actacaattc ctacatttgc
    13561 tgatagtaca aatgaaccaa ctactgtagt agataataac caagaattaa ctcctttaga
    13621 taggaacgga atagccattg gtaacccaac taacgactta actgttactg aaaattattt
    13681 aatagtttct ccattacttg ctcgagcagc ttctaaaacg atacgagtga caggaacgat
    13741 gatttttgat aaagttggtt ggccttctag acctcctcaa tcacggaatt ggaaagaaaa
    13801 aagaaatggt tattggtact atggaaaatt gtatttacaa agttataaat cagctggaaa
    13861 caattggatt gcgacttatt caggaacctt aactagaaag tagggatttt ttatgccaga
    13921 atttgtgaac acaccaaatt tttatcaaga tagcgatatt ctaagtaaaa ttaatttacc
    13981 gaaagaagaa tcagctttac aagttcagcg aactttacag gagacacaaa aaattcaaaa
    14041 atcaatttct aatctagaag attctgaaga aaaaagaaaa aaaagagacc aaaaaacata
    14101 tcaaaaagaa aaataatgat tttaaaaaaa gagtgtctag tcgacattct ttttttctaa
    14161 ttgaaagtgt tcataaaatc acccatttct ggacactttc tttttttgct ttatttttca
    14221 aaaaaacaat tcatttcatg ttcataaacc cataacaata tctatgttca gttaaactat
    14281 atggataaag ttatgttaca ataaaattaa tgaaggagtg atttttttga aaataggata
    14341 cgcccgggta tctactggtt tacaaaattt ggatttacaa gaagacagcc taaataaatt
    14401 tggttgtgaa aaaattttta ctgatcatat gagtggggca aaaagtaatc gaccaggatt
    14461 agaaatggcc attgattttg ttcgctctgg cgatacactt gtcgtttggc gcttagatcg
    14521 tttaggtaga aatatggaag atttgatttc aatcgtcaat cgactgaatg agcgtggtgt
    14581 gagttttcat agtattcaag aaaatattac gatggacaaa tcaagttcta caggacagct
    14641 catgtttcat ttgtttgcgg catttgcaga atttgagcgt aatttgatcc tggaacgatc
    14701 cgcagcagga cgagcagctg ctcgtgcaag aggacggttt ggtggtcgtc ctgaaaaatt
    14761 gtctgaacaa gatttggaat tactgaagac tttagtggat agcggtacac ctattaagac
    14821 tattgcggaa cggtggaacg tctcaagaac caccatttat cgttatttgg caaaaatgga
    14881 ggagaaaaat ggaaagacaa attctcatta gtttttgtca tttaatgctg aaaatttttg
    14941 ccatttatct agaaaagtga
//
LOCUS       DADQDV010000071        14808 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.073, whole genome shotgun sequence.
ACCESSION   DADQDV010000071 DADQDV010000000
VERSION     DADQDV010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14808)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14808)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14808
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.073"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            69..1808
                     /gene="yfcC"
                     /locus_tag="J8S10_002348"
     CDS             69..1808
                     /gene="yfcC"
                     /locus_tag="J8S10_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HAZ9630921.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPEGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            1965..3149
                     /gene="iadA"
                     /locus_tag="J8S10_002349"
     CDS             1965..3149
                     /gene="iadA"
                     /locus_tag="J8S10_002349"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HAZ9630922.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            3260..3463
                     /locus_tag="J8S10_002350"
     CDS             3260..3463
                     /locus_tag="J8S10_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HAZ9630923.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(3564..4226)
                     /locus_tag="J8S10_002351"
     CDS             complement(3564..4226)
                     /locus_tag="J8S10_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9630924.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(4239..5741)
                     /locus_tag="J8S10_002352"
     CDS             complement(4239..5741)
                     /locus_tag="J8S10_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9630925.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            6289..7968
                     /locus_tag="J8S10_002353"
     CDS             6289..7968
                     /locus_tag="J8S10_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HAZ9630926.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            8095..8574
                     /locus_tag="J8S10_002354"
     CDS             8095..8574
                     /locus_tag="J8S10_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HAZ9630927.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            8793..9473
                     /locus_tag="J8S10_002355"
     CDS             8793..9473
                     /locus_tag="J8S10_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HAZ9630928.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            9481..10812
                     /locus_tag="J8S10_002356"
     CDS             9481..10812
                     /locus_tag="J8S10_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAZ9630929.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            10827..11789
                     /locus_tag="J8S10_002357"
     CDS             10827..11789
                     /locus_tag="J8S10_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HAZ9630930.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            11900..12238
                     /locus_tag="J8S10_002358"
     CDS             11900..12238
                     /locus_tag="J8S10_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HAZ9630931.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            12317..13024
                     /locus_tag="J8S10_002359"
     CDS             12317..13024
                     /locus_tag="J8S10_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HAZ9630932.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(13127..14608)
                     /locus_tag="J8S10_002360"
     CDS             complement(13127..14608)
                     /locus_tag="J8S10_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAZ9630933.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLIKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
BASE COUNT         4690 a         2548 c         3175 g         4395 t
ORIGIN      
        1 gtataattca tttgattatc cattttttat tcatcaaaat tactgaaaaa agaaaggaag
       61 aaataaattt gaagaaaaca aattcttcag gaaaaccgaa acgcgacttc actaaattat
      121 cgacacccca tacgtatgtc attatttttg gtgtagtcat ctttgcatgg atactgactt
      181 ttgtcgttcc agaaggaaag ttcagcacgc aagatattga atacaaagat gcaaatggcg
      241 aaacaagtac tcgtactgtt ttacgtcaag attccttccg ttatgcttac gagctggata
      301 agtcgtatgt gtttgatcaa ttagaagaac tgcaagatca tccagcagaa cgtgaaaaac
      361 tggatgttcc ggaaaaagga ttggaaaaag tcattgctga cggagaaaaa aatcttacgc
      421 aggaaaaact agatgaaatc tccttgacag atgatgtgct ttacgatcag tacggcgaaa
      481 atatctatga tacttctaaa aaattgcata aaacagccaa aatatgggga acagatgatt
      541 ttggcggctt tggtttctta aattttgttt ttgaaggact agtatctgga gataagtatg
      601 gatctgctgt agggatcgct gcattgatcc ttgttgttgg aggtgctttt ggtattatta
      661 tgcgtaccgg agcgatcgac gcaggtatct atgcgtttat cagtaaaact aagggactgg
      721 agcgtttagc tttaccgcta ttattctttg ctttttcatt cggtggcgct acattcggga
      781 tggcagaaga ggtaattcca ttctcaatgg tgatggttcc atttgtcatt gcgttaggat
      841 atgactcgat cgtagcagta accgtgactt atgtcgcatc tcaagtcgga aatgcgacct
      901 cttggatgag cccgtttagc gtagcggtgg ctcaagggat tgctggaatc cccgtgttgt
      961 ctggtgcgac attccgattg attatgtggg tagttgttac tgcattagcc gctggttata
     1021 tgatgatata tgcagaaaaa atccgtaaaa aaccagaaag ttcgttgact tacaaatcag
     1081 atgattattt ccgttctcat atcaaaaaga catctgatga aaataaaaaa ttcatgcttg
     1141 ggcataaatt gatcttatta gagatgttag ttgtccttgt ctggatcgtt tggggcgtga
     1201 ctcaaaaagg ctattacatt ccagaaatcg cttctcaatt ctttgtgatg ggattagttg
     1261 ctggaatcat tgctgttctt ttcaaattag atggaatgaa agtcaatgac atcgcttctt
     1321 ctttccaatc tggtgcagct gatttagctg gtacagcaat cgtagtaggt atggccaaag
     1381 ggattcttct tgtcttggga ggatctgatg catctgttcc ttcagctttg aatacgattt
     1441 tgcatgggat cgggacggcg ttgaccggtg ttccagctgt cattggtgct tgggcgatgt
     1501 acatcttcca aagtttgttc aacttggttg ttacatcaaa ttcaggacaa gcagctttga
     1561 ctatgccaat catggctcca ctggcagatt tagtaggtgt atccagacaa gtagcagttc
     1621 ttgcttatca gcttggttca ggttttatgg acgcttttac acccgtatca gccagcttga
     1681 ttggtgtgct aggtgttgca cggatcgaat gggcaaaatg ggcaagattc caaatcaaga
     1741 tgcaaggatt cctgtttgtt ttaggaacta ttttcatcat gattgccatt gcaataggtc
     1801 tgcagtagta ctggagacct gtaaataaaa aagtaatcca aacagtagat aaggactcca
     1861 agaaccgtca ttttacggta aaatcaaagg agtaaagatc ctatcgtttg gattattttt
     1921 taagatccta tcatcagtta tacttaaaga aagaggaaaa atgtatgaaa atcattcgac
     1981 aaattgaagt gtttgcacca gattacttag gaaaaatgga tgtactgatt gccggtggga
     2041 agattttggc tgtagaagaa cagctagaag gcggctacga aggagtggaa gtagaagaac
     2101 tttcaggtga gggaaaagta ctaaccccgg gtttcattga ctgtcatttc catattttag
     2161 gtggaggagg agaaggcggt tatcaaaatc gaacgccaga agtcacattg agccaattga
     2221 ctacagctgg tgtaacgaca gttgtcggtt gtttgggaac agacggagaa ggtagagata
     2281 tgactgcgtt gatcagcaaa gcgaaaggtc tggaagcaga aggaatctcc acttatgtat
     2341 acgaaggttc gtaccgattg ccggtaaaaa cagtaacaga ttctatcatc aaagactttt
     2401 tgacaattga taaaattatc ggaatcggag aaatcgcagt atccgatcac cgttcttctc
     2461 agccaagttt tgaagagttc gctcgtgcag tagcagatgc tcgtgtagga ggcatgttat
     2521 ccggaaaagc tgggatcatc aatgtccact taggcggagg aaaaagaaag ctagagctat
     2581 tgacacgaat cgtagaagaa acagaaattc cgatcacaca atttttgcct actcatgcaa
     2641 atcgcacacc agaattattt gaagcttgcg tggcatttgc caaacgtggt ggcacgattg
     2701 acttcactgc tagcgaagat cctgattttt gggagaagac agatggtgaa gttcgcttca
     2761 gcaaagcact gaaacgattg atcgaggaag atgtttcttt agataatttc acgatgacct
     2821 cagatggaca aggaagcttg ccttattttg atgaaaacaa tcatttccta gggttaggag
     2881 taggaagtgc caaggcattg ctagtaggga tcaaagaagc tgtgcaaaaa gaaagtatcc
     2941 ctttggaaat cgccttacga gctataacca gtaatccagc acgtatattg aaattggata
     3001 aaaaaggaaa aatcgaaatt ggtgctgatg cagatctgtg tatcttggat aaagaaacgc
     3061 ttgatattga tacagttatc gctaaaggag aaataatggt ccaagaaaaa gaagtcaaag
     3121 tatgggggac tttcgaaaaa agtttttaat caacagctct aactatcttt tttagaaaac
     3181 gagcgttctg tttgtctgta tctgttgttg atgttaccct gaaggtagat caataaacaa
     3241 actaagagga ggaagcacaa tggcagattt aaaaggacgt tctaaagata tgaaagataa
     3301 agtagtcggt gaaggaaaag aagcatacgg caaagcaaca gacgacaaga gcaaagaaac
     3361 agaagggaaa gcacaatcac taggtgctga catcaaagaa aaagctcgaa atttaggcga
     3421 cgaagtcaaa gacaagtttt ctcgaaaaga cgaaaaaaaa taaaaaccac ttattactaa
     3481 ttgaatcaag caaataaaaa atccgaacca tatctgcgag acagatatgg ttcggatttt
     3541 ttatttgatc attatcctgt tttttaaact tcgatttttt gaaatttttt attttttagt
     3601 tcaaagactt catcacagct ttttgctact tcaatctcat gagtcacgat gataatacag
     3661 cgattttgtt catgggcgat ttcttggaaa agtttgacga tatcttgtga agttgtttca
     3721 tctagatttc cagtaggctc atccgctacg attagttgat gttcacagca gatagcacga
     3781 acgatagcga ctcgctgctg ctgacctccc gaaagtttgg tcacctgttt ttttgctaat
     3841 atttcatcaa ttcctacacg agccagtcga tctaaagcaa cttgtcgata attctcttgc
     3901 ttggtcttag tgatttccat tgctgctatg acgttgtcta gagccgataa ataaggaagc
     3961 aagttgtaag cttggaaaat aatcgagaca tcatttttac gataacttct taacccgatt
     4021 ttgttcagtg aacgatcttg atagtatacc tttccttctt ttggtgcatc tagtccagaa
     4081 ataagcgaaa gaaaagtcgt ttttccagaa ccacttgctc ctaaaatagc gtacattttt
     4141 ccagcttcga aattcagttc tacatcttta taaagcgcat cttgcggatc ttgataccaa
     4201 aatcccaatt gttctgtccg taacatcaaa ttcctccttt agtttaatag gatttttctt
     4261 gggtttaatc ttaatatccc tatagaagct aaaaagacag aaaacagact gattccaaat
     4321 gctactccgg ctaatagtcc caattgtgca ggtttgacat tgatttccaa ttcgctgact
     4381 tgatcagaaa cagcaaatgg attattcgtg gttccttgtt gaccatcgcg ttgaccgcct
     4441 tgttcttgtc tgttacctgg catttgtcca ccgccaggag cttgctggtt ttgtgtcgtg
     4501 gtttctgtct gttggtcaag tagctgctgt cccacggcat tcgcgacgac gtttccgcta
     4561 agcgaagcaa ctcctaatgc aagaatcata caaatagcca cttcggtaaa caattggaga
     4621 atgattttac ttctggattc tcctaaagat agcaagacgc ctaactcatg ccgacgctcc
     4681 cgaatggtaa tcataatgat cagagtaagt atgataatac cggctacagc cactagtaaa
     4741 acaacatttt tagaaaaact tgccacgttg tttaaaggtt ccaacattga ctgatacatg
     4801 gaatcatttg attgtaagct aaatgtatct gtgtcgatca gcttctcagc ttctttgaga
     4861 aactcatcca ttttatctgg atcagataga gtgtaaatag cagaatctat cgtgttatcg
     4921 tcagatgtcc catttagttc atttgcaaaa gtgtaagaag tgtaaagtgt attcgacgga
     4981 ttcatgaagt tgaatttcat acccatactg ccgcttgttt cgctggattc ataaattcct
     5041 ttgatcgtca tttcataagt ggtatcttca tcttcagtac tcgtgattgt gaaagtatct
     5101 ccgactgcca ggtcatttgt ttctgctaga gtagaatcaa tgactacatt gtttgtgcct
     5161 ttgtcgctgt catctattcc ttcaccatcc gtgatttttg ctgttccatc agaaaaatta
     5221 ctattttgtg cagttgctga cacaccactg atttgaaagt ctgcttgagt catttgcgga
     5281 ttcccgccca ttcctccagc aggttcaccg cctgcatcag tagtttctga actgtcttca
     5341 cttgaatcag aactagtgat ggcagttatt ccatcttttg ccatagctga ggcggaactt
     5401 tcaaaggaat aactctttac attatctaat tcagctattt tttccgcgtc cgttaaggaa
     5461 actggtgtaa gagaaaaact gcctggatct ggacgttctt cagtggtaga accgcttgaa
     5521 gaagtttgtt cctgtttttt aaatgaagct tctcgattgg cacttaaagt cactgttgct
     5581 ccaacttctt tttgtgcttg attcgctgct tcttctgcag cgcttcgaat cgtgaggcca
     5641 gctagcacaa aaataagaat ggctgtgaac acggcaaaca ataacaatga acgtccccat
     5701 tttacttttg tacttttcca tgcacgtttc ataaaattca tattttgcat ccctcctagt
     5761 agatgcattt gataatagac aacctatctt aaagctagct taaatcttat gctgtttgca
     5821 caccatcaac atgaggttct gtatatataa aaagtcacta tagttattgc aaaaaatgtg
     5881 gtaaaatgaa aaaagtatgt ttcaaaccga cgaagaagaa atgaaagagg aatagcaaaa
     5941 gaaatcctag atgctacaga gggattttta cgtgcatagt tgttctaaca attgctgata
     6001 ctagcgattt agtttatttg ttgtataata atggggaaca gctgaatact tatataagta
     6061 ttctggctat agcgtttcgc aaaagatcca ttttgttaat gaagtatatc caaaataaaa
     6121 tgcccatcca actgtcagaa cgcggatgtg ctggtaattt tcctgctgat tctccataag
     6181 ttgagaaata gtgattttgc atatgcttca ttggaatggc tcatatattt agataaagaa
     6241 gaaaatcgac atctttaaac ttggatgtca taagaagagg tgaagtttgt gagtaccatt
     6301 aaaattatcc cattaggcgg cgttcgtgaa aatggaaaaa acatgtatgt cgcagaagtg
     6361 ggcgaggata tttttatttt agattgtggg ctaaaatatc ctgaaaatga gttgttgggg
     6421 atcgacgtcg taatccctga ttttacgtat ttagaagaaa acattgatcg tgtagctggt
     6481 gtctttttaa cacatggaca tgcagatgcg atcggggcac ttccttactt gttgtcaaaa
     6541 atttctgtac cagtattcgg gacagagttg acgatcgagt tagcaaaatt gaatgtcagt
     6601 cgtaatgaag cagccaaagg atttaaggat ttccatgtgg tagatgagca tacagaaata
     6661 gactttggtg aaacagtagt gagctttttc cgtaccactc atacgatacc agattcagtg
     6721 gggatcaatc tgaaaacaaa agaaggtagt atcgtttata cgggagattt taaatttgac
     6781 caaacggcta tcccaatgta tcaaacagat tatgcacgat tggcggaaat cggcaaagaa
     6841 ggagtcttag ccttactaag tgaatcggca aatgcagaaa atcctcagcc tgtagcttct
     6901 gaagcccaaa tagcagatga agtatttgat acgatcaaat attgggaagg gcgtatcatc
     6961 gtcgcttgtg tagcaagtaa tttgcaacga gtgcaacaag tattggatgc agcagaaaaa
     7021 gcacaacgaa aagttgtctt gactggtcaa gatttcgaac gaattattcg cacagcgatg
     7081 cgtttagaaa aacttcaatt accaagtgaa gatctgcttg ttacgttgaa agacatgaaa
     7141 aactatgatc cagaagaact gatcatttta gaaactggcc gaatgggtga acccatcaag
     7201 tctctgcaaa aaatggcaaa cggtacacac cgtaatgtca agattgaaga aggagatttg
     7261 gtttatatca ctactacgcc aagcatcgcg atggaaacca tcgtggcgaa aacggaagat
     7321 atcatttatc gagctggtgg aacagtgaag ttgatctctg agaatatgcg cgtttctggc
     7381 catgccaatc ctaatgactt gcaattaatg atcaatttga tgaaaccaac atattttgtg
     7441 ccagttcaag gagagtatcg tgaattagct gctcatgcag atttggctca tgcagtaggg
     7501 atgccataca aaaatatcta tattactgga cgcggagacg tgctggaata taagaacaag
     7561 cgtatgagtg ttgcaggaac tacaagtgca gaaaatgtaa tgattgatgg attaggcata
     7621 ggtgatatcg gaaacattgt tttacgtgat cgaaaaatct tgtcagaaga cgggattttc
     7681 gtagcggttg tcactatcag tcggcgagaa aagaaaatca tttcaaaacc tcaaattact
     7741 tcacggggat tcgtttacgt aaaagctagc cgtgatctga tgaaagaaag cagcaatatg
     7801 attgaaacaa tcgttgagaa acatttagaa agcaatgatt ttgagtggag caaattaaag
     7861 caagacatcc gagatcaatt aggccgttac ttatttgaac aaacaaaacg ccgcccagtg
     7921 atcttgccag tcattatgga agctactcaa cgtcgaaata aaaaataaac aaaaagagta
     7981 agatgaacct ctctatagag tgctcgtctt gctctttttt tgcgaaaaac aaataatttt
     8041 tgaatacagc atccctcgct ttataataaa cgatagaata aagggagtga atcaatgatg
     8101 agtcaaacaa aagtcgaacg ttatttagaa gaacaaaaga tcagctatca accacttgat
     8161 tttagtcatg tggtagaaga atctttcaca gaagaactac aaaaaagagg gattgatcca
     8221 gctttgatat gtaaaactct cgtagtgaaa ggaaacaaaa ctggggtgat catcgcattg
     8281 attcctttga acgatcactt agattacaaa aaaacgagac aagtgacgaa agatcgtaaa
     8341 gttggttttc ctggaatgga ttttgtatta atgcatacag gatatcccca cggagcaaac
     8401 acccctattg gaataaaact cgcacatcct gattattgtt ttttagcaga cagttcttta
     8461 aaagaaaaag aagaagtaat tgtgtcaagc ggtgaaatcg ggagaagcct tcggataaaa
     8521 gtagccgatt tagaaaagat cgtccatcct atttacgctg atttaattag ttaagggacg
     8581 agaagagaag ctaagcagag cagagacctc aaacttgaga ttatatctgc ttggtacttg
     8641 gtgcatcctg tattatctgt tacaattgct ttgtacatac tgtactatca atccaatgaa
     8701 aatatattta gcagctatat tttttcattg atgtgcaagt gatgaaatcg tttttaataa
     8761 aaaagataca gagaaaacgc gaggtgtaaa atatgaaaat tacgtatcat ggacattcct
     8821 gtttaacaat tgaaatggaa aatggccaac gcgtgatgat tgacccgttt attacaggaa
     8881 atccattgac agacttaact gcagaagaag taaagacaga ttggttgctg attactcatg
     8941 gtcatagtga ccacatagga gatatgattc ctattgcaaa agaaaatcaa gccacaatta
     9001 tcagtattgt tgagattgct gattatgcga acagcagagg agtagattca ttcggtatga
     9061 atatcggtgg aaaacatgcg tttccattcg gcgtggtaaa attcgtacat gcacagcata
     9121 gttcaagcta tgaagtagac ggtatcgttc agtatatggg cgagcctagc ggaattatta
     9181 ttcaagcaga aggaaaaacg atttatcatg caggggatac tgcttatttc agtgatctag
     9241 gattgcttgc agaagaattc gatattgatg tcgctttctt gccgattggc gataactata
     9301 cgatggggcc agaagatgca gcaaaggctg cgcaaacaat tcgtgccaag aaagtagttc
     9361 caatccatta caatactttc cctgtcattg aacaagatcc cgaatctttt gtagagttac
     9421 tggaagatag tgaaggaaaa ataatgagcg tctcggaaac gctggaagtg taggcagaaa
     9481 atggcgacaa aacatgattt gattttagaa tatattgaaa gtttacctgt tggcaatcga
     9541 atttctgtaa gaagcatcgc aaaagaattg aatgtcagtg aaggaacagc gtaccgtgca
     9601 atcaaagatg cagaaaatgt cggactagtt tcaacaattc aacgagtagg gaccatccgt
     9661 atcgaacgca aattaaaaaa acatattgaa cgtttgacat ttggcgaggt cgtcaggatc
     9721 attgaagggg acgttttagg cggggcggca ggattagaca aggtcttgaa taaattcgtc
     9781 atcggcgcga tgactaaaca tgccatggaa cgctatatta cgccaggatc actaatgatc
     9841 gtcggcaacc gggcggaagt ccaaaaatta gcattggaag atggcgccgc agtattgatc
     9901 acaggaggat tcaatacgac tgctgagatt gcaaagctag ctgatgatct tgaaatgccg
     9961 atcttacgca cctcttatga tacatttaca gtcgcaacca tgatcaaccg agcgttaagc
    10021 gaccaattga tcaaaaaaga tatcatgctt gtcagtgata tctatatgcc agctgaaaag
    10081 actcattatt tgcagcagac agatacgatt tctgattatc agcgtttgtc agaagaaacg
    10141 cagcattcgc gttttccagt cgtcaaccgc catcatcgtt tgatggggat tgttacggca
    10201 aaagatgttt tagggaaatc gccaaaccag atcatcgatc gggtgatgac gaaagaacca
    10261 atcagtgtaa agaaaacaat gagtattgcc tctgttagcc atcaaatgat ctgggatggg
    10321 ctagaagtca tgccggtcgt ttccgatgac ttgacattgg aaggcttgat tacccggcaa
    10381 gatgtaatga aagcgatgca gcttgtccag cgacaaccgc agattgcaga tacgatttcg
    10441 gatcagatat ctggaaatat ccatacgatt gatactgacc gtgaaggaaa tcgtttggaa
    10501 aaccctaagt tcaaattcgt agtagcacca caaatggtca atggcgttgg aaccatttct
    10561 tttggcgtac ttagcgaaat catttctgat gtcgcacaaa aaacaatggt gatgaaccaa
    10621 aaacgaaata tcttgattga acaagtgaac ctacattatt tgcggctgat ccaattggaa
    10681 agcgaattag acattcgtcc acgtgtattg gaaatcggca gacgttccgc taaactggat
    10741 atcgaagtgt ttattgaaaa caccatcgtt tccaaagcaa tcgttgtttg tcaagtaatg
    10801 gaacgttctt agaaagcagg agtgaaatga cagtacagca agaaatagta gatacaataa
    10861 aaaaatacga taaaatcatt atccacaggc atttgcgccc tgatcctgat gcattaggat
    10921 cacaagtagg attagccgaa ctattacggg aaagtttccc agaaaaagaa atacgtcaag
    10981 taggtgaaac gattgaaggg cttcgctttt tagcagaaat gcaagaagtt gaagatgtct
    11041 tctaccaagg agcgctagtc atcgtgactg atacagctaa ttcacccaga atcagtgatc
    11101 aaagatatca gttggcagaa aaactgatca aaatcgacca tcatcccaat gatgaccctt
    11161 atggagatct tgtgtgggta aatacaaaag caagtagctg tagtgagatg attgcagaat
    11221 ttgctttgat gtttcctgaa tctttaaaga tgaacgttaa ggctgcacgg ttactttatg
    11281 caggaatcgt cggagataca gggcgctttt tgtatccctc cacgacgtcc cgtacattag
    11341 agattgcttc gatattgaga aattatccat ttgatgcaag tgctttgaac agagagattg
    11401 aacaaatgcc gatgaaagtc gctaaacttt ccggttatct ttatcaaaat atccaggtgg
    11461 atgaaaatgg tgcaggaaga ataatccttc cgcaagaaat tcttgataaa tatggaatcg
    11521 atgattcaga gacagcttcg atcgtttcac ttcctggagt gattgacgaa gtgctggctt
    11581 gggggatttt tgttcagcag ccttcagggt attaccgcgt acgtttacgt tctaaggggc
    11641 cgatcatcaa tgaattggct aaacgccatc atggaggagg ccatccatta gcaagtggtg
    11701 cgaatgcaaa agatttagca gaagtagagg aaatctataa agagatccaa gatatatgcc
    11761 aatcgtataa gagcagaaaa acagaatgat acttcgttcg aaaacgtgcc ttttgtagta
    11821 aaaatcacaa atgtatcttt tcaagatctt ctttttccgt tacaatagtg ctcactaaag
    11881 attttaaagg agaaagaaga tgacattacc aaattgccca gaatgtggct cagagtacac
    11941 atatgaagat cgaggcttgt tgatttgccc agaatgcggg aacgaatgga acaaagaaga
    12001 acaagaaact gtcatagaag acggattagt ggtattagat gcaaatggaa accgtctgtt
    12061 agagggcgat agcgtgacag tgattaaaga cttgaaagta aaaggtgcgt caggtgccat
    12121 taaacaagga acaaaagtca agaacatccg tttagtagaa ggcgatcata atatcgattg
    12181 caaggtagaa ggatttggac cgatgaaact gaaatcggaa tttgtgaaaa agaattaaag
    12241 aatattcaag gtcttttcac attcttttcc tactactaat gataaaataa agtaaacgaa
    12301 aaggagtgaa acgaaaatgt atggttatgg aatgtatggt tttttagatc cgacatttct
    12361 tttggtcatt cttggattag ttatttccgg aattgcgtca gcgtacgtca atagtacttt
    12421 ccgaaaatac gatcaagtga gaagcaaaaa caatgtgact ggtacacaag cagcacaata
    12481 tatattacaa agtcaacaga taaataatgt cggtgttcaa caaattgccg gagatctcac
    12541 agataactac aattcaggta ataagatgtt gagtttgtct caagcaactg cacagtctac
    12601 ttcagttgct gcgataggtg tagcagctca tgaatgcgga catgcggtac aagatgcttc
    12661 gggttatgtc ccattgaaga ttcgtgcagc acttgttcca gcagctaact ttggttcgat
    12721 gatttcgttc cccttgatta tggtaggtgt attgcttagc tggaactcta cgttaatcaa
    12781 tatcgggatt ttcgcttttt ctttagcatt acttttccaa ttggtgacat taccagtcga
    12841 atttaacgcg tctcggcgag caatccaaat tttgagtgaa ggcggactac tgacggaaga
    12901 agaagtaccg atggcaagac acgtattatt tgcagcagca ctgacttatg ttgcagcagc
    12961 gctttcgaca ttcctgcagc tgttgcgctt gatcttattg ttcggcggca accgaagaga
    13021 ttaaaataaa gaagttgtga aatcagcgct ttgatctgag ctaataccga gagttagctg
    13081 attgaatacc atttatttgg aataagagga tgtgacaaga attttgtcac atcctctttg
    13141 ttttgttctc ataacctttt ttcatataca gttcatgaac cgcttttatt aacttgccaa
    13201 ataacactgt attgtgcgtt gtatccagat agaaagtctc cgtttcatct gaaattttct
    13261 catgctgatc tgtaatgatc aaatcagcat gttctgaata tgcggtaatt ttaacagcat
    13321 ctttgcgaaa taactgctgc aaatggcttt gaagatgata atttcctgta aactgtttgg
    13381 ttatctgcaa atggatgagt aactgctctt tcgtttctgt ttgtagtaag tgttggatca
    13441 attgactaag gtattgactg atttggtttc tttccccatt ttttgaaaaa attgtatcga
    13501 ttttttctct taatttcttt tcctgtataa aagaactaga atgattggac gtggcttctg
    13561 gaaagcaaag tgtagaaaaa ctactgctgg attcacccaa cagttcgaaa aaaacaactg
    13621 ccaacacaag aaaataaaaa taaattggta ttttattttc taaatggttg agaggaaact
    13681 gttgagttaa gtaagtcatc aattgaccga cttgtcgaca aataaggttt ttgcttgtgg
    13741 aaaataaaaa accaatctcc tgtttttgtc gaaaagagat ttgatttgga aaaaaacaat
    13801 agaaaaaata attaaagtag gctctctctg tttctgtctc ttcacaaggg cgactcactg
    13861 aaaaagaagt aaagtattct gaataatcat gtgtatgctg caataagtcc atcaattcag
    13921 tgatttcaga agaagttttt ggaaaatatg cctgttgttt gtttcgtaat atgaataaag
    13981 ttaacagcaa gtagatattt ttttcttgtt ttgaaatttt ttctatttgc tcatctgtac
    14041 tgttcatttt tagtgcattt aattcaagtg aggaaaatgg ccaatcgtta cctccaaatg
    14101 tatctgaaag aaaaaagtaa agatagagac ggatagataa ctcatttcct tcaagagtac
    14161 agcaattttt tacagatagg atccgtaaat ggaattttat taaggaatga ttgagctgtt
    14221 ttgtcagttt ttcgagatag gagggcgata tataaagttg ttcaagtaaa tatttttttg
    14281 gtacagcagt ttgtggataa ttgattagta acatcaaata gttaaaacga ttggattctt
    14341 ttaggtagca taattttaac ttagaaaaaa cagctaactt tttagtttga tcggtttctt
    14401 tggtttggat ctctccttta tgattagaat aaataaattc atcaatcaat aaaaattgct
    14461 tgagtgatac atttattttt cggatcagtt ctttgattgt ccgttttgga atatgtaagt
    14521 cattggataa ttcttgtaaa gaacaattat ttttttgaat gaccatttgt agaacaagta
    14581 actctttttt tcttgcttca attagcataa atacctcctt tttattctgt ttttgtatat
    14641 agttagacaa aaactgtgag tggaaagtca tttcagtctg tgttattctc acagagtgtc
    14701 gccttctttt ttatataacg ttatttaatt tttttgttac cttgtttatt ctattgttta
    14761 tttcctaggg tattttgtca agatattctt gtttttaagg cggaaaaa
//
LOCUS       DADQDV010000072        13951 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.075, whole genome shotgun sequence.
ACCESSION   DADQDV010000072 DADQDV010000000
VERSION     DADQDV010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13951)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13951)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13951
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.075"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            168..362
                     /locus_tag="J8S10_002361"
     CDS             168..362
                     /locus_tag="J8S10_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630934.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            631..930
                     /locus_tag="J8S10_002362"
     CDS             631..930
                     /locus_tag="J8S10_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630935.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(1027..1461)
                     /locus_tag="J8S10_002363"
     CDS             complement(1027..1461)
                     /locus_tag="J8S10_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAZ9630936.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1693..2403)
                     /locus_tag="J8S10_002364"
     CDS             complement(1693..2403)
                     /locus_tag="J8S10_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HAZ9630937.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2393..3253)
                     /locus_tag="J8S10_002365"
     CDS             complement(2393..3253)
                     /locus_tag="J8S10_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HAZ9630938.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3258..3896)
                     /locus_tag="J8S10_002366"
     CDS             complement(3258..3896)
                     /locus_tag="J8S10_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HAZ9630939.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3911..4210)
                     /locus_tag="J8S10_002367"
     CDS             complement(3911..4210)
                     /locus_tag="J8S10_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAZ9630940.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(4253..5737)
                     /locus_tag="J8S10_002368"
     CDS             complement(4253..5737)
                     /locus_tag="J8S10_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HAZ9630941.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQALIFMGLILGCYWTVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5757..6218)
                     /locus_tag="J8S10_002369"
     CDS             complement(5757..6218)
                     /locus_tag="J8S10_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAZ9630942.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6236..7303)
                     /gene="ulaG"
                     /locus_tag="J8S10_002370"
     CDS             complement(6236..7303)
                     /gene="ulaG"
                     /locus_tag="J8S10_002370"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HAZ9630943.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7521..8291
                     /locus_tag="J8S10_002371"
     CDS             7521..8291
                     /locus_tag="J8S10_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAZ9630944.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8564..9391)
                     /locus_tag="J8S10_002372"
     CDS             complement(8564..9391)
                     /locus_tag="J8S10_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAZ9630945.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9959..11194
                     /locus_tag="J8S10_002373"
     CDS             9959..11194
                     /locus_tag="J8S10_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HAZ9630946.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(12193..12453)
                     /locus_tag="J8S10_002374"
     CDS             complement(12193..12453)
                     /locus_tag="J8S10_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HAZ9630947.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(12480..13781)
                     /locus_tag="J8S10_002375"
     CDS             complement(12480..13781)
                     /locus_tag="J8S10_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAZ9630948.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
BASE COUNT         4502 a         2843 c         2186 g         4420 t
ORIGIN      
        1 taagaacaat agccttttat tatatatatt attcaaatta gttatatcga gtgaaaaaaa
       61 ctttcaaatt gattcttttt atttatcata aagatataga tacataatca ttttcactta
      121 catatatttg aatattaact aaaaacagca agaaagaaga ggatcaaatg tattatgtag
      181 aagtaaaaac aaaaggcgtc aaaaacaaac aatatgtgaa aggtatcagt aacgaatatc
      241 ctttacttgg ttcatggaaa gaagctgctc ctttttccaa accatgtgcc ataaaaataa
      301 agaacgagct agaaaaagaa ctgacttgtg gtaaagctgt tgtagatatc atcgaaaagt
      361 aaatccaatg tatagaaagg aagatcacac atgaaaagcg acgtacaaat tgctaagatt
      421 atagaattag aagaagaaga cgcagtgttg acaattgaaa aaaaataaat gtttgtatac
      481 catatgatta tttcaatatg tatcctggaa ttggagatct cgtagagcta tatcaagatg
      541 aatcaaatat acttgtcatt catcatgaaa tatagagact tataaaattg tttattttta
      601 taatgtatca gtatagaaag gaaataaaac atggattata ctgttgaatt tgacagtgaa
      661 ctacttaagc aatttccaca agaagaacat ttcatgtata aagaagcaat ttcccacaaa
      721 gtgacagagt atttggagca taattttttt cgtataaagc cagtgcgtac tcgttcggca
      781 aaaggaatat acgagatgaa agtcaaaatt aataaaaaaa attatcgcat agcatttgct
      841 ttaaaaaaaa atcatgtgtt cattttttat attagttcga atttgcaaaa aattgtattt
      901 gataaagagg tgagtaaaaa aataaaatag ctgagcattg gaggatagat tgagtgatac
      961 taagtctatc ctcttgtttt tctaaagaac taagctagaa ttttttcttt tgtacgttat
     1021 tatatgttat ttgtcattac caaaaagcac cttttttctt ctagtatcta tgacataaga
     1081 aataccaccc atttccttta cttgaacaaa tcctactgat tcataaaatt tttttgtttt
     1141 ctcagtatca tctgtcaata attcgatttg gactggtcca taactagtga tcttctccaa
     1201 agcttcattc aaaagcactt tgcctattcc ttggcgctga tacctcggat gaatgaggat
     1261 atcttgaata aatgcgatcg tcgcaaaatc agtgatccaa cgaacgattc cgataatctt
     1321 cccttcccca ttacgcttta tcagagattc agattgttca aatgctctag ctaaccttgc
     1381 agtgtctttt gtgtaattcg tccaaccaac gctcttatat aattcagaaa tctcatcgat
     1441 cataagggaa tcaatattca tttttttctt cctttcttat acaattctcc ctctaataat
     1501 acagttcttt gactatttaa tctatcacat ataactctcc tgtaaagatt ctctcgattc
     1561 cttaaaattc ctctttcctt ttagaatgca tactttttga taaataaaaa ggttgtgata
     1621 aattttcttc acaacctctg tttctctcta tcaagtgtta tcttttaatt ttctaccctt
     1681 accctagcat ctctattgcc cgtagtatgc atactttcca tgtttgcgaa aataatgttt
     1741 atctagtaaa tattgcggga tttcacatat attggggttg atcagctcgt tttctttggc
     1801 catcagacaa atttcatcta agatcaaact gttttctact gctttcatag gtgaatcccc
     1861 ccatgtgaac ggtccatgtc catagacaag tactccaggg acttcgtttg gatctaattt
     1921 tctttcctta aacgtctcga caatcacatt ccctgtatga acttcgtaag cttctcttac
     1981 ttcttctttc gttaattggc gtgtacaagg aaccttacca taaaaagcat cagcatgagt
     2041 cgtgccataa gctggcaaat cgcgtcctgc ttgcgcccac atgacggagt gcgtggaatg
     2101 agtatgagta atagcagtta tatcttcaaa agtttgatac aaaacaacat gtgtggggag
     2161 atctgaagat ggttttaagc tatcttcttc tattatattt cccgacaaat ctgttaccac
     2221 catttgatct gcttgcatgc attcatatct gacaccgctt ggcttaatga cgatgactcc
     2281 tagctcacgg tccacttcac tcacattgcc ccaagtcaat ttgactaatc cgtatcgcgg
     2341 caatgccaga tttgcttcaa ggacacgttg cttcattgct gcaatttttt cttcacaaga
     2401 catcatagcc agcctccttc aatttagaac ttaagtagtc ttttgcctgc tggatttctc
     2461 ttcgaaagtc ttggcttttt tcactccaca tttcaatcag aaatgttcca tcataatcta
     2521 gacgtttcaa atgtcttaat aatccaagaa aatcaacaca accgctacca aaaggaacat
     2581 cacgaaactg gcctgaatat tcttttgtta cagggtaagt atcttttaag tggatagcag
     2641 tgatataatc gatccctttc tcaagttctc gagccggatt attttccggc catgcggaca
     2701 aattgcctag gtctggatat acttgtagaa aaggtgaatg aatctgttct ttgatttcta
     2761 aaaattttga aatggagttc ataaatggat catccatgat ttccacggaa agaatgatgc
     2821 catatttaga agcttccttt acgctttctt ttattccttc gataaagtct tctctggaat
     2881 tcattgattt ctcttcataa taaacatcgt atccagctat ttggattact ttgacgctta
     2941 gattatgcgc caaatggatt gcttttttca ttagttgttt cgctgctttt ttcttttctg
     3001 gatcagcaga accaaacgga aatcgccgat gcgcacttaa acaaatcgaa tggatacgta
     3061 caccggagct gaacatctct tctctcagct cagctatctt ttcttcagac caatctaatc
     3121 gtgctaaccg ctcatccgtc tcatcaatcg acatctcgat aaaatcgaag tccatttctt
     3181 ttacaaggga aaaacgttct ttccatgaaa tatctttggg taacgctttt tcataaatcc
     3241 caatttgagc catttcctta cccccagata cgaatgatct catctttgaa gttttgtgcg
     3301 gccttcatcg gatcatttgc tgctgtaata ccacgaccag tgataaaggt atacacatcg
     3361 atcccttcaa ataagtgtaa tgtgtgtgga tttaatccac cagttacaga aacattaaag
     3421 cctagttcaa tcagtttttt gatcttcgat aaatcttttt caccccaagt ttcaccagat
     3481 aacagcgcat cacggctttg atggtagatt acctgccgga taccgatgtt atgccaatcc
     3541 atggcttgtt caaaagtcca attgccgtag agttctactt gcaattcacc tatttctttt
     3601 tgtgctgcct ccatagttgg aatcgttgca caacaaatga ctgtcatcca gtctgctcct
     3661 gcttttgcaa cattactcgc cactgttcct ccagcgtctg cacatttcgt atcagcgact
     3721 agttttttat ctgggaacat actgcgaata cagcgaatcg ctttttgtcc ttcctgtaag
     3781 caaagaattg tgcccacttc aataatatct actacatcac caactttcat aacatctcct
     3841 aatgcatgtt ctaagtcatt gtgatctaac gcaatttgca aattcggcct gctcatctta
     3901 gttccttcct ttacttgttt ttttggtacc actttgtttc agcaaatttt tcactgattt
     3961 ctttgactga catcacattt ttgataccga taactgtaac tccttttttc tctgcctgag
     4021 taaacatatt caaaaaattg actggcgtaa aaactacatc gtattggcca gctgaacttt
     4081 ttccctctga aatggcacaa tgatggattt tggtaattgg tacgtttagt tctttcattg
     4141 ctttttccac acttctcatc atcatcaagc ttgttcctga tccatttgca cacgatacta
     4201 aaattctcat cttaatccct ccattatgag tgttgtctaa tcagattttc ttttatactc
     4261 tctgcttttc tgcatatgtg tcatagtctt ctacaatcaa aaaataacca tcaggatttt
     4321 tccgatattg taactgcgga atagccaata aaccaatgac aactacggca attccagcat
     4381 aacctaggac tttcatgatt actgtaaaca atggccaagc tgttgcccag tcgaacatcc
     4441 cgatataacc accgtatgtt gacatcccaa tccatgtagc gaataatgct gaaccgccta
     4501 cttgtatgat tcctgaaaga aacgggaaca ggcaagcggc tttgaatcca cctcggttat
     4561 tggcataaac tgctataacg gcattatcaa agaacaacgg aatgaaaccg gctatgacga
     4621 tcgttggtga tttcaataaa atcagtaaac caatcatcaa aaactgtccc aaagcaccaa
     4681 acaagaaccc aatcgttacc gcatttggcg aaccaaagcc aaaagtagca gctacgtcaa
     4741 ttcctggaac agctcctggt aaaatcgtgt ttgagattcc ttggaaagat tgagttagtt
     4801 catcgacgaa tgtccgaaca cctaattgca agatcgccag atataccgca aaatttaaag
     4861 aagtcgtcat aatgtagaat aagaaactct gcccttcttg catgaattgc gcttgaatca
     4921 aataatcttt gcctagtaca atcagaatga tcccaaagaa aaatagcatg agtaacgaag
     4981 tagcaaccat attctcattg aaaatcgaca agaatcctgg taatttgata tcttcaattt
     5041 ttttgtcttg cttgattgat ctatttttct tttcatcccg ctttttcatc cactcagcta
     5101 attttgcaaa tataaagatt ccgaacattt gctgatgtgc cactgcaaat ccggcacctt
     5161 ctgtcaattc ctgcgtgatt cctactgtta agttagaagc tactgtccaa taacaaccta
     5221 aaatcagtcc cataaaaatc aatgcttgta tcctacctag atcaggaaag caaaacagta
     5281 aaatccaaaa agcggtagct gcttgttgaa cctgaacgtt tccggtagtg aaaacggaac
     5341 gcagtttcgt atatttctga aaacggacta ataagatatt taaaacaaat gcaatcagta
     5401 ataaaatcat cacatctcca aaggtacggc caaatgtctc cattaatcca gcatccacag
     5461 cattttgtcc aaaataagga tctgtaacca tggcatccaa attgaaccgt tcctttagtc
     5521 caaccaagat tggccgaaaa ttattgacca aaccaccaga gccaacagtc aaaataaagt
     5581 aaccgaccgt tgcctttaag aatccagcga tgcattcatg aagcgggcgt ttcagcaaaa
     5641 tatagcctaa taacacgata aaaccaatca ggtatgctgg ctgcgtcaag atatttgttg
     5701 caaaatacgt ccaaatgctt aacaaaaatt cccccatctt ttttctcctc tatcaattaa
     5761 ttatattctg ccatcacaac ttggtaatca tcgatggagt tcgtagagat gagacgctca
     5821 accaatccat ctgtcattaa taattcggat aatttttgga tattttctag atgttcttct
     5881 ggatcttttg ctgcgagtgt aaaaaacaaa ctagccgttt tctcctcatt ctccccttca
     5941 ctttcaaaac ggattggctg tttcaacttg gtaaatgaaa tagctgttcc aaaaacacca
     6001 tcactttttt ctgaagaatg cggcattgct acttgaggtg cgatcacaat ataaggaccg
     6061 tatttttcta cacaatggat gatctcctcc acatacgttt catcaataat ttccttatcg
     6121 atcaatacaa gacagctttc ggcgatagct tcacgccaat ccgtgatttc tttatctggg
     6181 taatgaatca attgatggtc aaaaaagtat ttcagcaaga aactcccctt ctttcttata
     6241 aaaacgacgg aaacggtgta tcattttcaa tcgagaagac atcttcaaat cctcgataaa
     6301 aattaaactc aagatcatct ttgtttgtcg gatagatgaa tttcccgcct acttgccaga
     6361 tataaggttt aaatccatac ttcaggcgat cctttttgaa tttccaaatt tcagtgatct
     6421 cttttggatc agccataaaa ttagaccaaa tatcgtagtg gacaggaatc actacttttg
     6481 cattcaatga ctccgccatg cgcagcatat caacagaagt aactttgtct gttatccctc
     6541 gtgggttttc accataggcc cctaaacaga catcgatttt gtgttcatta ccatgtttgg
     6601 caaataaatt ggagtaatgt gaatctcctg catgataaag attccctcct gatgtttcga
     6661 ataaatagtt tactgcaatt tgatccatct cctgaggcat ttttcctttt aatacctctt
     6721 ctggatcttc acaagtgacc aacgctgtcc gatcaaacgc ttctaaagct actacattga
     6781 tgtctttgat tttgactgca tcacctggct ttactgtaat cgttttttct tcaggaattc
     6841 cccatttttg ccacgtgcga accacttctt ttggcccaat gaatgttgct tcaggacaat
     6901 tttgatgaac tgctgcggct gtatggatat ctagatgatc ggaatggata tgtgtaacga
     6961 ttaaagcgtc tacatttttt atcgcaaaag gatcgattac gaaaggctga gtacgtaaat
     7021 taggctgcat attttgaacg ccactcatac gcatcatctg atggcctttt ttcatcatgc
     7081 cattcccatg actacgtttt cccgtcccac accatagatc acataaaata ttcgttcctt
     7141 catgactttt cagccaaatt cccgtacagc ccagccacca catagcaaaa gttccaggat
     7201 ccactacttc tgtttcgatt tcttcattca agtatgtgcc ccactcagga aatgtttcta
     7261 ctaaccactt ttcttttgtt acttcattga cagttttact catttgcttg ctccccccat
     7321 atcgttgttc caacttacaa gtaaatatta atgtgtatca gcatccatga aaaccctttt
     7381 atatgaccgt ttgtttttta tatgattttc tttcagtaat caatgattgt ttcagtataa
     7441 taaagacaga tatgaatgtt taaatgaaca actagtcaaa taaatccatg gatcaagatg
     7501 tccctcagga ggcaaaagtc atgaaaaact cacttgtcaa tattgaaaaa cgtcaaaaag
     7561 aaattttgga actgcttcag cagactgaac aactatcaac tttcgaatta gctgaatccc
     7621 ttgatgtatc tattagtacg atacgaagag atttaaattt attagaagaa aaaaacgaga
     7681 tcatacgcaa ttacggttat tgttcttata attacaaaaa ccagactgat tttgatcaat
     7741 ctggtcctga aaggattaaa caagcgattg ccagagaagc tagtaaatac attaacgatt
     7801 atgatacgct gtttatcaat tctagctcga ctgcgttgaa aacactggat tttcttcaat
     7861 ctaaccattt gacagtcatt acaaacaacg tgaaaatcaa ttactctccg cacaaagata
     7921 attgtagtta tattttaact ggtggagaga tgcgctttcc aaaagaagca ctagtgggcg
     7981 acatcgcatt aaatacgatt tcttcagtca atgcagacat ttgtatcatt ggctgtagcg
     8041 gagtcgatgt agtacatggg gtcacaacaa agatattaaa tgaatcaacg atcaacgaaa
     8101 tgatggtcaa caagacaatc aaatgtaaga ttttagtcgc tgatcatcga aaaatcggac
     8161 tgacatcaaa gttcaagatt gctgatattt cagtctttga ttatttgatc actgataaat
     8221 tttgttctga aaaagtatta gaggagatca gaaatacggg gataaaaacc attcaagtag
     8281 attcatttta agaaccagga cgtaaatatg taaataggat tatcaaaaaa atgaataaca
     8341 aatttatcga taaatgaaaa acacgctacg ctcaaattga taaaggaatc ccaagatgta
     8401 tccatccaat cgataccatc ataatctatt gcttctttta taaccgttat atgttgccta
     8461 aataggaatc aaacaatatc gaaaaaagga ggtatgacaa aagtcacacc tccttttttc
     8521 gaataaacgg tattcaaatc agaacactga tttcacaacc actttatttc aggtcgtttt
     8581 caatcacctt taccgcgtaa tcatttccgt tgaaacgcgc tatttttttt gcgtccatat
     8641 atctttctaa ataatcatct tctcctaatt gcttatggca agaagcaatt tcataaagca
     8701 agtattccaa tgcataagtc gatttatgtt tcttattata ctcaataccc ttctcacata
     8761 attggattgc tttatcataa tcctcgattt tacggtaata ggtggcgata tcataatata
     8821 caatgcagac catcagatta tcaaaatcag tctcactcaa tattttaagt gtacgctcca
     8881 cataaacttt cgcaaaatct aattctcctt ttgacaagta gatcattgcc acgtttgcag
     8941 ctgcttgtaa gtgatggata tctgtttcgg tcgtttgttc caacacttga ttaaaataaa
     9001 ataatgctgc atctggtttt ttcgcataaa gatgatcaag cagtccttga taaaataaaa
     9061 tttgatttaa aagatcagaa ttacttactt tttcctgatc gatcgtttgt aaaattttat
     9121 aagattcttg gtattttgat acagaattca atgattgaat ctcatttatt tttttcctga
     9181 ttttgtcttc ttctgtttct actaatatat cggagatctc gacattcagc tttttgcaaa
     9241 gcgcacttaa gatattgatg cctggcgaca tattcttgtt ttcgatattg ctgacagttg
     9301 cttgttcaca aatgccttct gctaattgta cttgtgttaa cccctttttc tttcggtatt
     9361 cttttagtaa tgctccatct actttaatca aaacaatttc cttcccttta aaaaattatt
     9421 tctcctttat atcatacaca aaaaaaagtt ctaaacaacc aaaaatgttt agaacagaat
     9481 aaaaatttta attttaaaat aatattcaaa ttaaacaact ggcgtatctg ctccttgatt
     9541 tctttttgtg ttatctgaat aattatcgtt tacagttata acacatagtg aaaattgtca
     9601 tggcgagaaa gtctaagaat atttttaaac ataactattt ctttcttacg tgtgtataat
     9661 gacgacagca cacctatcaa ttaatataat tattttattt ttttatgttc tcatgtttat
     9721 ttttaatgac acaacttctc gtatttatct ggcacaacat ataaatcgat caaaaaattg
     9781 ttgcgtgttt ttttgaaaat tggagtttca acttgattac aaaatttaaa tttagaagtt
     9841 gtgaaaacag cgagagacag tttaatattc aaaatataca taggctactc gaacgctgtg
     9901 ttttttagta tactagtaag aaacgaaggg atagactcat tccaataagg aggatttcat
     9961 gaagacaatt ctttttgctc ctgcagtatt caatttagct gagacaacac gaatgattga
    10021 ggttgccaaa gctatgaaag accgttatta ctgtgtattc tttggctttt ctaaaacttt
    10081 tgctcctttg atcacagaaa gtggctttga gtatcattta ctagcgccga tccttacgaa
    10141 aaaacaagaa gaacaaatca taaaatttga ccagttgcgt acacttaaaa acccttttac
    10201 caaagaaatg gttgcctctc gtatcactag tgaacagagt ctgattgcta agtttgagcc
    10261 tcgactgatt gtgacaggtt cgaatgtgac aattttttta tcggcccgca ataaaaagat
    10321 tcctttagta tatgttaaac cctatgcttt gagtgaacct ttttttcaat cagagcatgc
    10381 gctgatgccc cacgagttac gtttcttcgg ccctttaagc aatccccttt ggcactggac
    10441 aaaaaagcgt atagtaaata cccgatggat ccccaatgcc ttcaaacacg ctgcacaaaa
    10501 agaaatgctt cctttaccaa aaacaagttt acaaatgatg gatgctgatc taaatctcat
    10561 cacaacgcct aaactatttt tggaagaaga acagctgccg gaaaattatc gaatcgttgg
    10621 tccaattttt gctaagctca gtacttcctt gcctgaagaa gtgctaactt ttatacagcg
    10681 aaagcaacaa gaaagaaaac gtattatcta tttcgcaatg ggtagttcag gcaatccgcg
    10741 tatgttacgc aaaattttgt tcttcttaca aaaacaaccg gatctagcgg ttattgcacc
    10801 tattgactat ctgcttgatg acattcaatc tgactcagaa gatcttttaa taacagaata
    10861 tctgtctagt catcttttgc atgaattcat tgatttttct tttatccacg gcggggaagg
    10921 gaccgtccaa actgcctgtg aatccggcaa accgtttatc ggtgtgggga tgcaatttga
    10981 gcaaagctgt aatattgact attgtgtaaa atacggaaac gcaatcgccc tcacaaaacc
    11041 agtgactgaa agaaaactgc agattgctct gcgcgaagtt tcttcaccca agattcgtca
    11101 gcaggcacgc acgctgcaag ccgtttttcc aataaatggt ccacaacaag caattcaaga
    11161 aatcgaaacc ttcctgagca accacccaat atagtttcaa gtagaaaaag cttttttaat
    11221 agagactcat cagtaatttc gctattcgag acccagacag tgaaaataca aaaaaagtaa
    11281 atagtggatt gaaaagttag agttacttaa attacggtgt ctaaaaaaca caaaatcatc
    11341 cttaaaataa aagatctgac gctatccaaa tgagcatagg tagcgtctgc catttattct
    11401 tagtcaaatt ctttgacacc tttctctggt tggatcatct caacgtttct tcaaaagaaa
    11461 gaccataata attaggcaaa tacattttct taaaatgtgt catatagatc tagaagcatc
    11521 gctttgtaga gatttgtgcc gctagtcccc tcaacaatta ctaaatcaaa tgtaggattt
    11581 accactttat ctttgataat caacctccct cttctgttga gacaatgatc tcgcaatccg
    11641 atgcatactc ctatataaac tgccagcaat ccccacatat tgagtagatc atgtcagaat
    11701 gttctatgtc gtcagcaacg atacactaaa agtcacgttc accatgactg attgctattc
    11761 ccagcacaat tatttctata cacgtttcat gatttgaata aacactcaca tcatacatat
    11821 taccattcat acaccatact gcagccccta ctatatggtt gtaagctccc aaatctatat
    11881 ttgacttgat cactttggta gtagatctac taattctaaa tccattgctg ataaaatttc
    11941 cattttttcc tccttctttc tgccaaaaca gttaaaacaa taataatctt tatgtaaaaa
    12001 agggctgtga caaaagcctt gtcacagtcc catattccga ataaacggtg gtcaaaagct
    12061 tgcatctgcg gtaataagtt caaccaaacg aaaaataagc caacatttca caaaaattta
    12121 agaagcaatt ttcgtaaatt tcttcttatt tcttgaagct aaccacttct gttacaacca
    12181 cttttagaac atttaaagct tcgatgtgac aaaccatcta tgctgctcga tcataaaatt
    12241 gatagcaaaa attccacaaa gtacatatgt cccccatgaa aacaaaacat tcatatgcgg
    12301 tacaatgatc tttggaagaa tcacgatcaa aaatgatgcc agtgcccaaa tccatcgatt
    12361 gatttgaata tgatatgtag ctagcatatt caatataagg tgactagccg ttaataaaaa
    12421 gataaaaaca aaaaataaaa tcagccaata cattgtttcc caccttctaa aaaccaaact
    12481 tagacagtct ggacttcgtt ttctccacga ctttgttcat ctgacagcat ctttttatca
    12541 taagctttta caaatggata atagataata aatgctatca atgtgttgat catgatcaag
    12601 ataacaacac gccagtcatt tcctgctgaa agataaccgc cgattggagc tggtaatgtc
    12661 catgttggca aaacagtaaa tctattgacc atttctaatt tgactgcaaa ataactgata
    12721 atagtcaaaa ctaaaggaac taagttgaac gggatgaaca tgtaaggatt caacatcata
    12781 ggagctccaa aaattatggg ctcattgata ttgaagatac caggaataat agaaaaacga
    12841 ccaacctctt tcaagaattt tgatttacag aagaatataa acaaaacaga taccacgatc
    12901 gttgctcctg caccaccaat tgttaccgtc cattgataaa actgttcagg agcgatatag
    12961 ggtaattggg tggcagctgt accatctgcc aatgcctttg cattctcatc caacatgatc
    13021 agccacattg gacgaacaac agcccctaca atactcatgc catggatacc aaatgaccac
    13081 aacaaatgga tcaaaaacat tggtagtaaa acaccaagca aattattccc taaaatattg
    13141 gttaaaggct cgaataacga taataaggca gcgtttacat caaagcccgc gacgcttcga
    13201 atcagccaag taattgttaa aatgactgca cctggaatca atgcctcaaa actacgggca
    13261 acagcaggtg gcacttgttc tggcattttg atagtaatat ttcgattttt aaagaaacga
    13321 tatacttcca ctgcaaaaat catagataag atccccgcaa acatcccaga tgctcccaaa
    13381 gaactcatag gtaagaccca gccaagaggt gcctcttcag gagttaaaac gtttacagga
    13441 acttgtaaca taaagaacgt tcctaaagat aatataccac ctgtcacact atctaatcca
    13501 tatgatttag ctagatccga acccataaca aaagttgcat aaatagccat caatcccatc
    13561 gtcatcctaa agggtaaaac aatcgttgcc gaataagggg caataaattc attccatcca
    13621 ggaaacggta aattgataaa gaccataaaa aatgtcccaa tcaaaatcaa tgacaatgtt
    13681 gaaacaaccc cattacgaat tgctaataaa tgacgctgtg taccaatttt tgccattggt
    13741 gggacaagtt tctcttcgac ccatttcatc agcttttcca ctaaaaccac tccttttcaa
    13801 taaaatatga accattcatt gcatgacaac gcaaagaatg ttcataacta attatataat
    13861 taagaaattt tatttcaata tattctctta aataatcaaa tttattttta agaatcctga
    13921 aaataagttt tctaaatcat aggagcaaca a
//
LOCUS       DADQDV010000073        13917 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.076, whole genome shotgun sequence.
ACCESSION   DADQDV010000073 DADQDV010000000
VERSION     DADQDV010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13917)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13917)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13917
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.076"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            131..505
                     /locus_tag="J8S10_002376"
     CDS             131..505
                     /locus_tag="J8S10_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HAZ9630949.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(619..1248)
                     /locus_tag="J8S10_002377"
     CDS             complement(619..1248)
                     /locus_tag="J8S10_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAZ9630950.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1382..1454)
                     /locus_tag="J8S10_002378"
     tRNA            complement(1382..1454)
                     /locus_tag="J8S10_002378"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1419..1421),aa:Thr,seq:ggt)
     gene            1668..1741
                     /locus_tag="J8S10_002379"
     tRNA            1668..1741
                     /locus_tag="J8S10_002379"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1702..1704,aa:Asn,seq:gtt)
     gene            1696..1845
                     /locus_tag="J8S10_002380"
     CDS             1696..1845
                     /locus_tag="J8S10_002380"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630951.1"
                     /translation="MTVNHDVVGSSPTAGVNKAYAKKKKSNHLGFFFFYYYDESSFLF
                     LSRML"
     gene            2338..3666
                     /locus_tag="J8S10_002381"
     CDS             2338..3666
                     /locus_tag="J8S10_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HAZ9630952.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            3868..4701
                     /locus_tag="J8S10_002382"
     CDS             3868..4701
                     /locus_tag="J8S10_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HAZ9630953.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            4717..5454
                     /locus_tag="J8S10_002383"
     CDS             4717..5454
                     /locus_tag="J8S10_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HAZ9630954.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(5609..6577)
                     /locus_tag="J8S10_002384"
     CDS             complement(5609..6577)
                     /locus_tag="J8S10_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HAZ9630955.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            6809..7642
                     /locus_tag="J8S10_002385"
     CDS             6809..7642
                     /locus_tag="J8S10_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HAZ9630956.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            7676..8515
                     /locus_tag="J8S10_002386"
     CDS             7676..8515
                     /locus_tag="J8S10_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAZ9630957.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            8541..9101
                     /locus_tag="J8S10_002387"
     CDS             8541..9101
                     /locus_tag="J8S10_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAZ9630958.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            9300..11021
                     /locus_tag="J8S10_002388"
     CDS             9300..11021
                     /locus_tag="J8S10_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HAZ9630959.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            11186..12328
                     /locus_tag="J8S10_002389"
     CDS             11186..12328
                     /locus_tag="J8S10_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAZ9630960.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            12344..13555
                     /gene="thiI"
                     /locus_tag="J8S10_002390"
     CDS             12344..13555
                     /gene="thiI"
                     /locus_tag="J8S10_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HAZ9630961.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
BASE COUNT         4751 a         2298 c         2833 g         4035 t
ORIGIN      
        1 ctacactctg agatgtaaga aatatcataa gatatttctt acatcttttt gttttgagca
       61 ggactttaga taattttatt aatatatgct agcatgcttt tgtaagaaaa agaaagaggg
      121 cgtattagtt atgtatctta aaattacgga acaagcacaa gaaagattac aaaaatatat
      181 tgatgaaggc gcaacagtta tattggattt agatgatggc gttggggaat attctaaaat
      241 gggtgtttgc tctttagata ctagttttcg tttacttctt cttgataaag aacagagaaa
      301 aaatgattat aaactccaat tagatagtga tattggggat gtttatataa aagattattc
      361 aaaaatgtac atggatgaac atatgaccct ttctttagat ccacgtctag gtgtatttac
      421 tcttgaaagc ccaagtggtt ctttagacag tcatgttcaa ttagtagatc tacgaccaga
      481 aaaattctct ggaataaaac aataactttc tctctattgt ccataaaact agtctcaatc
      541 aagctgtatt gaaaaaacaa gacaacattc ttaccatggt aaataaaaag acgacacatt
      601 ttgtcgtctt tttttaaatt aactattttc gataaaagat cgcatagctt gtgccattat
      661 ttctggcttt tctctattca attcatgttt tccgttttta ataaagagta gccggccatt
      721 cgttgaaagt ttatataaac gttttgctgc tggtttattc gcatgatctt tggtaccgca
      781 taaaatcaat ttaggaagtc gtgatgtacg aagctgtttt ttgcagtcta atgtttcaag
      841 tgaacgaagt agggtaaggg tttgtttttt agatagacct aatttttcaa atatcttaga
      901 aggtacgcag taaaaataaa tattctggaa agtaagcaat aagcgattag gagactcaaa
      961 ttgtggagcg actaaaacaa ccttttttaa atatggagaa ggagttgcaa gatagtttaa
     1021 agcaataaca gcgcctaaag ataatccaca taaaataaaa ggttccttta tctgattcaa
     1081 ttgtacttcg atgtatttgg ttaagtcgtc taaagtagca gtgtctgtgc tgtttaaatg
     1141 attgaacaat gaaagacttt tgcaagaata actattgggt agataagaga ttacatcttt
     1201 ccatgattgt tcgtcttggc ctagaccatg caaaaaaaca attttcatat tgctctcctt
     1261 tttatagtta tcatatagac tttctttgta ctattaaaat ataaacattc atttcttacg
     1321 tcataaaata aaaaaacagc gcagacacat tgttaaacca acatgttgca ctgtttaagg
     1381 aagccacttg ccgggcttga accggcgacc tcttccttac catggaagcg ctctaccagc
     1441 tgagctaaag cggcattatc attaatacaa ataataggat aacgaatatt aatgtatttg
     1501 tcaacagaat tttttcgaaa aaatgtgttt ctctaatagg aaaacagatt ttagaaaaaa
     1561 taaaaataac aaaaaatgcg aacggtttct ttgataatat aataaaaaaa ttcaaaaaaa
     1621 gtattgcgtt atttagaaga aattgatatt atattcatgt acttgattcc ggcatagctc
     1681 agttggtagt agcgcatgac tgttaatcat gatgtcgtag gttcgagtcc tactgccgga
     1741 gtaaataaag cttatgcaaa gaaaaagaaa tccaatcact tgggtttctt tttcttttat
     1801 tattatgatg aatcaagctt tctgtttttg tcacgtatgt tgtaatcttt acgaaagagt
     1861 agagttggct actcataatc aaccatactt cccatcatcg ctaaatacga aataaatcag
     1921 cattcctaca ccaatcaaag cacaagctgc accaagaaaa gggatgacat tcccaaagtt
     1981 atctgtattc ataagtatgc caccacccac aaacaaaaag ccgccagcaa tcaggttttt
     2041 cattttattc atctcctttc ttacgttata gtatttcctt ctttcaatga gtattttgaa
     2101 agctatctta ttgtatgatg ttcttctagg cctcttcttt attatacagg ccattttcgt
     2161 tatctcatag aaatattcct ttttatctga aaactattgt ataccgtatg acatttttct
     2221 tcatgaagtt gtaagtatat tctcattcaa atgaaaattt catcatagaa gagattgtat
     2281 ttctaaattc ttaagagtaa aatacgaagt ataacttgga tttggaagga tgattggatg
     2341 aaagctatta cgcctgatat gacaacaaaa tttaacaaac agtttcaagc aaatatcaaa
     2401 cagcaggcat tgcagcgggc agttgtgaag aacggaatta ctgcttctgc tgaaaatgtt
     2461 tcagcacatg tggagaatac accggtattt tctatagatt tggctacggg gaaagtggct
     2521 aatcaaatgc aatcggggcg ttgctggatg tttgctgcac tgaacacatt ccgtcataag
     2581 atgctgaatc aattccattt aaaagagttt gaattatcac aaaattacac ttttttctgg
     2641 gataaatatg aaaaggcaaa ttatttctat gaaaacatca ttgcaacagg aaaagaggca
     2701 atcgatagcc ggaaagtagc tttcttactc gctactcctc aacaagatgg cggccaatgg
     2761 gatatgatcg tttcattatt ccaaaaatat ggcgttgtgc ctaaatcggt gatgccggaa
     2821 agtgcgaata gttcaaattc tcgagatttg aataactact tgaacaaatt actgcgtaaa
     2881 gatgcagtag tgttacggaa aatggttgct caaggagaaa cattagacgc tattgaagaa
     2941 aagaaagaag aaatgctaga aagcatttat aacttcttag ctatctcatt aggaacacct
     3001 ccaaaagaat tcgattttga gtaccgcgat gaagaaaaga actatcatct tgaccgagga
     3061 ctgacaccac aaatttttta tgataaatac atcggtgtaa aattagatga ttatgttagc
     3121 gtgatcaatg caccaacaaa agacaaacca ttcaatcgtt cttatacagt agagatgcta
     3181 ggaaatgtcg ttggcgggaa agaagtcaaa tatctgaatg ttgatatgga aactttcaaa
     3241 aaattagcga ttgctcagct tgaagaagga gaatctgttt ggtttggttg tgatgtaggt
     3301 caatcttcta ctagaactag tggcatcatg gccttagatg cttattcaat ggatgatcta
     3361 tttgatacgg attttacaat gactaaagct gaacgtttag attttggaga aagtctgatg
     3421 acccatgcga tggtattgac cggtgttgac ttagtagacg ggcaatcaac aaaatggaaa
     3481 gtcgaaaata gctggggcga aaaagttgga aagaatggct tctttgttat gagtgatgcc
     3541 tggatggacg aatatacgta ccaaatcgtt gtaagaaaag atttattgac gaaagagcaa
     3601 ttaaatgcgt tcaatgaaga accaattgtt ctatctccgt gggatccaat gggtgcttta
     3661 gcatagacga gtatttcaat gaagagtatg tagtaaagat aaaaagagct ggcttaagcc
     3721 agctcttttt atctttaaag tccattccct gttttttatg gtccctgtgc tataattcta
     3781 aataaaggat aaggattgga aataatcctt ttatcattaa aaatatgatg acgaagtaga
     3841 ataaaattgg gagtaggggg gaaagtcatg gatatccaaa ctgttttatc tgatctgaaa
     3901 ttaaatggta aagtgattcc agttgttggt ggcgatgtta atcagaccta tcgtataaaa
     3961 accgaacatc gtgcttattt tttaaaaatc catccgaatg taaaaaaagg attttttgaa
     4021 gcagaagtag acggattaaa agaactgtca gcattcgtac gtgtaccgga tacgtatatg
     4081 ctaggtgaaa caagtgaagg cgcttatttg ttaatggaat ggatcgagcc gggaaaaggg
     4141 gatcaacgag atcttgctgc agctttagct aatctccatc agcaaacagc gccacaattt
     4201 ggttttcgta aagataacta tttgggtaca cttgttcaga aaaattcttt tgaagaagat
     4261 tggtggactt ttttctttaa agatcggctt gaatcccaga tttctttggc agaagaaacg
     4321 aatcgatgga atgtacagcg tcaagaaaag tatctgcgat ttaaagaacg tgtattgaaa
     4381 tcggttgaac caaaaaagat cactccacgc ctcttgcacg gagacctgtg gagtggtaat
     4441 gtgttctttg accagcaagg gcatccagtt tttgtcgacc cagctgtttc ttatgggaat
     4501 cgggaacaag atattgcaat gagccagtta ttcggtggtt tccgaccgga atttttagat
     4561 gcttatcaaa ctatatttcc attagaaaag ggatggaaag accgactgcc gatttaccag
     4621 ttatattatc ttttggcaca tttgaatatg tttggagaaa gttacggttc ccaagtagat
     4681 caattactag aaaattttta agaggagggc gtgtttttgg caaaaaaata taccaaaaag
     4741 catgaagttt catattatga gtgtgacatc aaccaaacga tgacatttcc ttcgatgtta
     4801 ggagtagtta tcaaaacgtc tgaagatcaa agcgaccagt tgggaagagg cagtgaattc
     4861 gtcaatagct ttggacttac ttgggtcatc acgaattatt ccatggagat taatcgtctc
     4921 cctagagtcg gtgaagtaat ctcagtaacg actcaagcca tggagtacaa taagtttttc
     4981 tgttatcgga acttctggat ccatgatgaa gatgggaaag aattagtcaa aatagaatct
     5041 gttttcgtat tgatggattt tgtgaatcga aaaatgagca gtgttaatga agagatcatt
     5101 gctccttttg agagtgagaa gatcaagaaa atcaagcgtc aggaaaaaat tgaaaagatt
     5161 gattcgggct tcatgttgcc atatcgtgtt cgtttttatg atatcgatag taatcagcat
     5221 gttaataatg cgatgtattt taattggatc attgacgtat taggatatga ctttttgact
     5281 acgcatgttc cagaaaaagt aattattcga tttgataaag aagtagagta cgggaatgag
     5341 atcgaaagcc attttgaaca aatccctatc gaaaatggtg tcaaaacaaa acatgaaatc
     5401 cgaatgcaag aacagctgta ttgtgaagca aatattatat ggaaaaataa ataaaaaaga
     5461 ggttgtgaca gaagggggca acttcaagaa ataagaagaa atttacgaaa attgtttctc
     5521 aaatttttgt aaattttcga cttagttttc gaagaagcta tttttgtcac agcctctctt
     5581 tttaagttta gctattagat aatgatgttt agttttggat aaacgaaatc aattcttcac
     5641 ccgacaaacc atagtttaca gcaatcaata gttttaaacg tgctttttga ctattaatac
     5701 tgttacagaa aataatcccc attttttcta gttcttttcc cccgccttca taatcataaa
     5761 caggctctgc gattccattg aaacaacgag aaacaagtac tacagggatt ttttggacaa
     5821 gaagcttttc caaagcagct aaggcttgtg gagggagatt ccccgcacct aaagcttcga
     5881 ttaccaaacc gtctactttc gtatgggcga tggcttccaa taagtcccct tgcatcccag
     5941 catatgcttt aacgatcggg atagtcccat ctacagcgga aatgtccagt cgctttgttt
     6001 ctaaaagttc ctgcaagaat aaaattcgat tcttagttac taagccgatg ggacccaatg
     6061 taggtgttcg gaaagtagca acatttgtgg tatgggtctt tgtcacgtag cgtgcagaat
     6121 ggatctcatc gttcatgacc accaaaaccc ccttatctag cgcttcttca caacttgcga
     6181 cacgaatcgc actttcaaaa ttataaaggc cgtcacttcc aagttcatta cttgaacgca
     6241 ttgccccagt caaaacaatt ggtaatttgt tgccaatcgt tgtatcaaga aaaaaagcag
     6301 tttcttctaa tgtatctgta ccgtgtgtga tcaccactcc ggatatacct gatgcataag
     6361 cggacaagat acgttctttt aataccaaca tgtgagaagg catgatgtgt ggtgagggaa
     6421 gattgaagat atcttcaact aataattcta catgcttggg gattgtgatt tctgcatcta
     6481 ataatgggtt tgccacatca ggactaacac cgcccgtgag catgttttct ttcatggcga
     6541 tcgttccgcc ggtgtgtagt acaagtattt ttttcatttt acagacttcc ttacgaataa
     6601 ttttgcatag ccgttaaatc ttattgtata ctatataaaa gagttttgct atcagtgaag
     6661 aataacgaat agcctaactt atcataaaaa agctgacctt attaaaatgg aaaagactca
     6721 accttgacct cctaatacaa tggagtatct ggttgagttt cttttacaag aaagcagcca
     6781 aggaaatcaa tcacgaaggt ggccggaaat gatcagaatc ggattaacat cgtttaaaga
     6841 acatgacaaa ttaactggta aaaagaataa cactctttat gaatatgcag ggtttctacc
     6901 cttagtggaa ttagatactg cctattatgg aattccccga aagtcctcag ttgagaattg
     6961 gataagtgaa gtacctgaat catttcgctt tgtagtcaaa gtctatcaag gaatcagcgg
     7021 tcaaggagac tggaagcctt attatcagac cgaagaagag atgattgcgc attttttaga
     7081 tgttatgtcg ccaatggtag atgctggaaa gatgttttgc tttttagtcc aattcccctc
     7141 atcattcaaa tgtacgaaag aaaatgtcca gtacttgcgc aaacttagaa agtggtttga
     7201 gggttatcct gtttctatag aattgcggga ttattcttgg tacagcgatg aatttcttga
     7261 acgtacaaga aactttatgt ctagagccgc tttttcttta gccatcatcg atgagccaca
     7321 gttgctgaat acaacgattc cttttgatcc atttgtcacc aatccgaact ttgctctttt
     7381 tcgattccat ggtaggaatg cgcaaggatg gcaagcaaat gataaagagt ggcgtaaaaa
     7441 aagaacgtta tatcgttatt cagaaaaaga actgcaagaa ctagcacatg aagtcaaagt
     7501 agttgattct aagacaaaag aggtaggtgt gatttttaat aataattctg gtggtgatgc
     7561 ggctgaaaat gcattagcac tgcaaaaaat attaaatatc aagccagatg gactcaatcc
     7621 aacccaaatg gatctgtttt aagggcttat tttattcaag aaaggggcga agtctatgat
     7681 caaagctatt ttttttgata ttgacggaac attggtcacc aatcgttcaa aagcgttgga
     7741 atcaacaaaa caagcaattg aatatgctcg gaaaaacggc attttatgcg gtgtagcaac
     7801 ggggcgcagc ccagtaaaga tcaaagaaat cattgatgaa ttggaattag atatgtatgt
     7861 cgtgtataat ggtcaactgg tttttactgc agatcgcacg attatcgacc acccttttga
     7921 acaaaaagta ttggaacata ttgttgaatt tgcagatgag aaccatcgac aaatcgtttt
     7981 tggtgcgaga aatcggttag atggatcaac gacgatgcta ttaggacaat cgatttttat
     8041 caagcgacta gtcagctttt taccgcgtaa attcccggta cgtctgatga aaaaaatcct
     8101 ccaggttttt agccctcacc gacaaaagga tcgttatgaa acgttagaga tattaaaaga
     8161 accaatttat caatgtatat tgctcagtcc ggagtcagaa cagaaaaagt tagaacatcg
     8221 ctttcccgag tgtacgtttc agcgttcaaa tacgtatact gtagatatca tcccaaaagg
     8281 tggttcaaaa ttactaggca tccaagcttt cgcaaatgct gtcgaaattg aaatggaaga
     8341 aattatggca ttcggcgatc attacaatga tatcgagatg ctgaaaggtg taggaattgg
     8401 agtggccatg gggaatgctc agatcgaagt aaaacatgct gcagactttg tgactcaatc
     8461 aaatgaagaa gatgggatat acgaaggact gaaacacttc ggtctgattt attagtcaat
     8521 gaaagaagga aaaaatcagt atggaagcag agacaccttt tcaaaaagta gaaacattcc
     8581 acaaaacttt tgatccaaga agaccagaga tacccacggc ttttacagaa aatgaagctc
     8641 atacacgtgc tgcgttcaaa atagaagaac ttgttgaatt tgttgcagct acttcaccta
     8701 ataaagaaca actgcatgaa gctgttatgc tgctgcacga agcattagat aaagcagaag
     8761 aaaaaatact tggtaaaaca cagtggggaa gtgatccgct ggttgaacaa gtagatgcac
     8821 tgacagatat cctttacttt acttatggtt ctttttcatt actaggaata gtgcctgatc
     8881 gaatattcga aatcgtccat caggcaaata tggggaaatt atttccagat ggaaaacctc
     8941 attatgaccc tgtaacaaat aaagtgttga aacctgaaaa ctggcagatg gaatatgctc
     9001 cagaacctaa aatcgcggca gaaatccaac gtcagattca agaagcgatt gctaagaaga
     9061 aatccgctga tataggcatg tgcacaaatg aaaaagagtg atcagagttt cactattttt
     9121 gttatcttta tacgatggaa aaacaaaaga ttttcgttta agttagtgaa tgcatgaaaa
     9181 tagtatgcta taatctagaa tagatgtctt ttgcacgaga gacgtattat ttggatttat
     9241 gccaagcaga acgccatctg ttgcataaaa gatgcatact gaaaacggag gaaccataaa
     9301 tgggaaataa tgttatcatc ggaatcgtca ttgcaatcat tatagtcgcc attgtcgtct
     9361 ttttggttag ttacttgatg aagaaaaaaa accaagatcg attggatgcc ttagaaaaac
     9421 gcaaggaaga attatttgac ttgccagtga ttgaagaagt cgatgatgtt aaaaaaatgc
     9481 atctggttgg gcaaagccaa aatacctttc gtgaatggag tcaaaaatgg aatgacatat
     9541 ctacttcctc gttcgctgaa ctagaaagtc aaattttcga agtggaaaac ctcaatgaaa
     9601 gttttcggtt cttaaaagga aaaaaagcag ttgttgaagc agaagctaca atggaccaaa
     9661 tggagaaaca agtgacggaa atccgtgaag gtctaaagga attgcgggaa acggaagaac
     9721 gcaactcact agctgttcag caggcacttg acgtctatga agaactgaaa gaaaaagtca
     9781 gagaagacga gcatgaatac ggaccagctc tttttgaatt gcaaaaacag atcaaagtga
     9841 tcgaaaaaga atttacgcag tttgtgactt taaacacttc tggagaccct gttgaagccc
     9901 gcgaggtttt ggataaagca gaaaaacata cgtatgaagt ggaagctctg atgaaaaaaa
     9961 ttccaccgct gtatgaggag ctccatacca ctttccctga acaacttgaa gaaatcagtg
    10021 atacttacga gaaattgatg gaagaacaat atgtattccc agaagaagat cttgctgaag
    10081 atatcgcaaa agtaagtcga agaattgaaa attcattagc caatcttgaa aaaacagaag
    10141 ttgaaacggt cgaatttgaa aaccgtgaaa cagctgattt gattgattcg ttatatgata
    10201 tcttagaacg ggaaatggaa gctcagagat atgtaaaaac taaccaatca acgattgcag
    10261 agtatatcaa acatacaaca aagaataacc gtcaattatt gattgagctg gatcacacat
    10321 ctcaaagcta tacattgaac cacaatgaaa ttggccgtgt acgaggtttc caaaccgaag
    10381 tggaagaaat ggaacgtcaa aatgaacaga tgattccaca gatccgtcaa cacgaaattc
    10441 cttattcaga agtgcgcacg ttctataaaa cagtcttcaa agtcttagaa gatatcgaaa
    10501 agcaacaagt agagatcgac gactcattac atgaattgag aaaaggcgaa aaagaagcgc
    10561 aagaaaagat cgatacattc gaattcaaat tgcgcagttt gaaacgtttt gtagaaaaac
    10621 aacgtttgcc tggcttgccg aatgattacc tagaattctt ttttgttgct actgaccgta
    10681 ttgaagaact aagtgttgtc ttgaataaaa ttcgagtaaa catggaagag gtcaatcgtt
    10741 tagttgctct atgtgaagaa gatctagaat tattagataa gaagacacat gatttagtag
    10801 atgcagcagc attaacggag caaatgctcc aatatgcaaa tcgttatcgt catacacacg
    10861 aagaagtgag agaagcaatt gataaaagct actatttatt caataaagaa tatcactatc
    10921 aagaagcatt agacgaaatc ggtacagcat tagagcgagt agaacctggt gctttcaaac
    10981 gcatcgaaga tttttatttt aatcatccag acttagtata aagcaaaaaa gttagtaaac
    11041 cagcaagagc aagacggatt attgtcttgt tcttgtcttt ttttgtatat ttgaaaattg
    11101 aaacaagtga aaatttcacc tgctcttgaa agcaccttgg acaaccgtta taatagaaaa
    11161 gaatttcaaa aaagaggggt ttcttatgat atattttgat aacagtgcaa caaccccaat
    11221 ctttccgcaa agcttagatg catatgtaaa aaccagtcag cggattattg ggaatccatc
    11281 aagcttgcat gatttaggca atcaagctaa ccggttgttg cagcaagcaa gaaagcagat
    11341 cgctgatttg atccatgtag aaccagaaga aatctatttt acttcaggcg gaacagaagg
    11401 agataactgg gtattaaaag gaacgatgat cgaaaaaaga gaatatggga atcatatgat
    11461 catttcagga gtcgaacatc cggccgtcag cgagacagca gaacaattaa aagaattagg
    11521 aatcgaagta agtatcgccc cagtggataa acgcggattt gtacgtgtcg acgaattgaa
    11581 agaattaata agaaaagaga cagtattagt ctctgttatg gctgtgaata atgaagtagg
    11641 atcgattcag cccatccagg aaatcagtga tcttttggat gattttccta aaattcattt
    11701 ccatgtagat gctgttcagg cgattggaaa agtaccattc tcgcaatggt tgacagaaag
    11761 agttgatttt gcaacatttt cagctcataa attccatggc ccacggggaa ctggtttcat
    11821 ttattggaaa aagggtcgtc gtttagcacc attactgaca ggtggagggc aagaaagaaa
    11881 tcagcgaagt gggacagaaa atgttccagg tattgtggct atggttaaag ctttacgttt
    11941 atcattagag ataaaggaac aaaaacctga gcagacacaa cgcttaaaag tagctctaat
    12001 caatgcgttg aagacgtatg agaaagtgac gattttttca gaaggaactg actatgcacc
    12061 gcatatttta tgttttgctc taaaaggaat tcgcggcgaa gttctcgtcc atgccttaga
    12121 agaaaaacaa atatttgttt ctactactag tgcctgctcc tcacgtaaac atatggcaag
    12181 cagtacattg cacgcaatgc atgtaccaaa tgatctggct acatctgctg ttcgaatcag
    12241 cttagatgaa aacaattcgc ttgcagaagt cgagcaattt atgattattt tcaagcagct
    12301 ttataagaaa ttttctgcaa tcaattaaaa gaggagtgtt cttgtgaaat acagtgaaat
    12361 tatggtccgt tatggggaac tttcgacaaa aggaaagaat cgaaaaagct ttatcatgca
    12421 actagcacaa aatgtcagac aagctttgaa agactttcca gaaatcaaaa tccatgctga
    12481 tcgggaccgg atgcatcttt tattgaatgg cgcagacggg cagctagtta ttccaaaact
    12541 agcaaaaata tttgggatcc aaaatttctc tccaagtatt cgtgtagaaa aagatgtcga
    12601 agttttgaaa caagctgttc aagacatcat gaaagaaatt tatactggga aagaaacatt
    12661 taaaattatc gctaaaagaa gcgatcacca atttgaattg acaagtaatg aattgaatca
    12721 aacattaggt aatgctgttt ttgatatttt cccgcatatc caagttcaaa tgcgtcaacc
    12781 agatattcca ttacgtgtag agattcggcg tgatggcgct tatctatcgt atgaaacgat
    12841 caagggagct ggaggattgc ccgtaggaac aagcggaaaa ggaatgctta tgctttctgg
    12901 ggggattgat tctcctgtag cagggtactt tgccatgaag cggggagtgg aaattgaagc
    12961 tgttcatttt gctagtccgc cgtatacaag tgaacaagca ctgcaaaaag caaaagatct
    13021 aacagccaaa ctagcacctt atgtgggaac gatccatttt atcgaagtgc catttaccga
    13081 gattcaagaa gaaatcaaaa agtcagtgcc acaaggatat tggatgacaa ttactcgtcg
    13141 aatgatgttg cgtttgaccg atgaaattcg ccgtattcgt catggtttag tcattttgaa
    13201 tggtgaatca ttaggtcaag tggcttcaca aactttgcaa agtatggtgg ctatcaatga
    13261 agtaacgaat acgccaatca ttcggcctgt agcgacaatg gataaacttg aaatcattga
    13321 agtagcagaa cagatcgata catttaatct ttctatccag ccttttgaag attgctgtac
    13381 gatttttgct cctccacagc caaaaacacg ccctcaactg gaaaaggtcc atcaatatga
    13441 agagcgttta gcaatagatg aaatgatcca acgagcacta gctggcttga agatggaaga
    13501 gatacaagca gaatcgtcta atgaaaaaac tgaagaattt tcagaattgc tataagaggt
    13561 tatgaaaata gtgttttgac cagagtatta gagaaacaaa acgaaaaaat agctccatgt
    13621 attttaccgt ttttgaacta atgtcgaaga ttagctgatt gaataccatt tatcaagaag
    13681 ttatggaaaa gccggttctt ttttactaac tgaaaaataa aattttattt agagatcaag
    13741 ctacagttga taaatgatat aaaaaagaga atttcccatg aaatagcgag gttgtgacag
    13801 aagtgggcag cttcaagaaa taagaaggaa tttacgaaaa ttgcttttca aatttttgtg
    13861 aaatttcggc ttatttttcg aagaagttac ttctggaaca ccgtgtatca gaggttg
//
LOCUS       DADQDV010000074        13897 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.077, whole genome shotgun sequence.
ACCESSION   DADQDV010000074 DADQDV010000000
VERSION     DADQDV010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13897
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.077"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(161..2158)
                     /gene="tkt"
                     /locus_tag="J8S10_002391"
     CDS             complement(161..2158)
                     /gene="tkt"
                     /locus_tag="J8S10_002391"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HAZ9630962.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2260..2511)
                     /locus_tag="J8S10_002392"
     CDS             complement(2260..2511)
                     /locus_tag="J8S10_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HAZ9630963.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2658..3281
                     /gene="lexA"
                     /locus_tag="J8S10_002393"
     CDS             2658..3281
                     /gene="lexA"
                     /locus_tag="J8S10_002393"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HAZ9630964.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3461..3679
                     /locus_tag="J8S10_002394"
     CDS             3461..3679
                     /locus_tag="J8S10_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630965.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(3968..4480)
                     /locus_tag="J8S10_002395"
     CDS             complement(3968..4480)
                     /locus_tag="J8S10_002395"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HAZ9630966.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4494..6791)
                     /gene="recJ"
                     /locus_tag="J8S10_002396"
     CDS             complement(4494..6791)
                     /gene="recJ"
                     /locus_tag="J8S10_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HAZ9630967.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(6933..7367)
                     /locus_tag="J8S10_002397"
     CDS             complement(6933..7367)
                     /locus_tag="J8S10_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HAZ9630968.1"
                     /translation="MKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPLILV
                     IIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQREFRN
                     ERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7377..8165)
                     /locus_tag="J8S10_002398"
     CDS             complement(7377..8165)
                     /locus_tag="J8S10_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAZ9630969.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8162..9103)
                     /locus_tag="J8S10_002399"
     CDS             complement(8162..9103)
                     /locus_tag="J8S10_002399"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HAZ9630970.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9280..9867)
                     /locus_tag="J8S10_002400"
     CDS             complement(9280..9867)
                     /locus_tag="J8S10_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HAZ9630971.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10088..11401)
                     /gene="obgE"
                     /locus_tag="J8S10_002401"
     CDS             complement(10088..11401)
                     /gene="obgE"
                     /locus_tag="J8S10_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003126661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HAZ9630972.1"
                     /translation="MSMFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGG
                     DVILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAET
                     GALLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVL
                     ADVGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLE
                     RPQIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNAT
                     ADLLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTN
                     FDHDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11689..12699
                     /gene="gap"
                     /locus_tag="J8S10_002402"
     CDS             11689..12699
                     /gene="gap"
                     /locus_tag="J8S10_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HAZ9630973.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12784..13719)
                     /locus_tag="J8S10_002403"
     CDS             complement(12784..13719)
                     /locus_tag="J8S10_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAZ9630974.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
BASE COUNT         3848 a         3106 c         2452 g         4491 t
ORIGIN      
        1 tcaagaaaca caaactaatc cgaagaattc tttgttttgt catttaaatg taacatagcc
       61 gaaaacgaaa agtaatattg atttattctt ctaacacata aagaacagct gtctccaact
      121 tgcagacagc tgttcttatc agtcaaacaa ttgcttggat ctatgatagt tgattgtacg
      181 tattcacgac attttctact gtaaatccaa attcttctaa aattttagtg ccaggggcag
      241 atgcaccgaa atgatcgatt gtaatcgttg cgccctctgt tcctacgtag cgttcccatc
      301 caaatgatgc agcagcttcg atagccacac gtttcttcac tgatttagga agtacacttt
      361 ctttatattc agaagattgt ttttcaaaga ggtcaaagct tggcatagaa acaacagaaa
      421 catctttgcc tttttcagcc aattcttttt gagctttcac agccaaatca acttcagaac
      481 ctgttgcaat caaaatacct tctggtgttt ctccttgtga tggagaaaga acatacgcgc
      541 cttttttcac catttcatct gctacttctt ttgtagaagg caatactgga aggttttgac
      601 gactcaatac aaggatagta ggcgcatctg ttgtctccat cgctactttc caagcagcac
      661 gtgtttcatt tccgtctgcc ggacgaatca cttgaacacc aggcatgcag cgaacagatg
      721 ctagttgttc aatcggttcg tgcgttggtc cgtcttctcc gacagcaacc gagtcatgtg
      781 ttaagacgta aacaacagga gtatgttgga ttgctgctaa acgaactgct ggtcttagat
      841 aatcgacaaa gacaaagaat gttccaccgt agatacgagt tccgccatga agttggatac
      901 cattcatagc cgaagccatt gcaaattcgc ggacaccgaa ccagatgttg cgtccttcat
      961 aatgttcagg agtgaaatct ttatctgcag ccaccattgt attattggaa cctgacaagt
     1021 ccgctgaacc accccagaag cttggtatag ctttcgataa ttcttggatg acttctttac
     1081 ttgaaacacg gcttgcttga ctgcttccaa cttcataagt tggcaattct gcatcccagt
     1141 tttctggtag tttgccatca aaagcatctt caaattgttg tgctaattca ggataagctt
     1201 ttttataatt ggcaaacatt tcattccatg catcttcagc tttttgtcct tcttctatca
     1261 tcgtttgatg gaagcgggca gctacttctt ctggaacagt gaaatctgga tactcccaac
     1321 cataaacttc tttagccatc ttgatgccat cttcaccaag aggagcacca tgaacagcag
     1381 atgttccttc tttaggagca ccatagccga tgactgtttt tacttcgatc aatgttggtt
     1441 tgtctgtttc agcttttgct tcttcaatcg ctttagagat tgcttctagg tcatttccgt
     1501 ctttcactaa gatatgttgc cagccatatg cttcatagcg agcaccaacg ttttctgtga
     1561 aagcttttga agttggaccg tctagtgaaa tatcgtttga atcgtataaa acgatcaatt
     1621 tccctagttt catatgacct gccatcgaac ttgcttcttg agatacccct tccatcaagt
     1681 ctccgtcacc gcatattgca tacgtatagt gatccatcac attaaagttt tctttgttat
     1741 acgttgctgc aaggtgcgct tctgccattg ccataccgac agccattgca atcccttgtc
     1801 ctaatggccc tgtagtggct tctacaccat ctgtatgatg tacttcagga tgtcctggtg
     1861 ttttagaatc ccattgacgg aattgtttca aatcatcgat tgtcacttga tagccagcta
     1921 aatgaagcaa gctatacaac attgctgacc catgtcctgc cgaaagaacg aaacggtcgc
     1981 ggtcagccca gttttttgat gtcgttggat ttactttcag gtgttttgtc cataacgcat
     2041 atgccatagg tgctgcgccc atcggcaatc caggatgtcc tgagtttgct ttttggactg
     2101 cttcaatact taatgtacga attgtgttaa cgccaagttg gtcaattttg tcaaacaaaa
     2161 taacccctcc tattaattta ggtttttttt acctttattt cttacacttt cattctataa
     2221 gatgtcacac gaaaaagcaa tctttttcag tattttttac taaaagttgt catttcggtt
     2281 gtgtaagcct tttttctttt ggatttcttt taatttttcc ggggtcacgt cattgccctc
     2341 aggatcgacg actttcattc cttcgatatg atgacgcata ccggaacgaa aagcttccaa
     2401 atactctttg cgcaagttga tttgttcttg ttcttcggct tttgagagac cattttcctt
     2461 ctttttacgt gcaagttcat tgatccgctc tattttttca ggtgacagca tgctcagccc
     2521 tccttttact ctccttcata ttatataaaa actgaaaaaa aaacaactag ataaactaaa
     2581 taaaatacga acattcgttt gatttagcgc tttttatatg gtactattta tttatcaagt
     2641 gaaagaaggt gtaccttgtg gcccgacaaa ctgaatcaag acaaatcgaa gtcttacgat
     2701 atatccatga acaagtaacc caaaaaggat acccgccgac tgtccgtgaa atcggggaag
     2761 ctgttcagct ttcttctact tctactgttc acggtcatct tgcacggctt gaaaaaaaag
     2821 ggtttatcca aagagatccg acgaaacctc gtgcaatcga gttgacaaaa caaggtttag
     2881 aaaagattgg gattcgtcca acaactattc cagtacttgg cgtcgtaaca gctggagaac
     2941 ccattttagc agtagaggat gcttcagact tctttccaat ccctcctaat ctttcttccg
     3001 aagaaggcag tctctttatg ctgacaattc gtggagatag tatgatcaat gctgggatat
     3061 tggatggtga caacgtgatc gttcggaagc aagaaactgc tcaaaatggc gatattgtca
     3121 ttgcaatgac tgccgaggac gaagcgactt gcaaacgatt ctataaagaa aaaaactttt
     3181 tccgtctgca gcctgaaaac gacttgctcg aaccaatcat cttagatcaa gtatctatat
     3241 taggacgagt agtaggactt tatcgtagtc atatctatta attgctacta attaaaagaa
     3301 aactttttaa aaagagtttg agacgttggt ctcaaactct tttttcgccc gggttcttct
     3361 tctttcaaat ttttatcact tccctcttta caaaccgaac aaatattcgt atactaaata
     3421 tacgaacaat tgttcgcata aattaaagag gtgagaattc atgaaatcaa tgagacgtct
     3481 tggcttagta ttaactgttt tgtttttagg tattattatt ggtaatttcg gcatacgtcc
     3541 agctttactt gtgtttgttc cgttatttac tttgtggttc atgttgtggg atgaaaagaa
     3601 gtaccgtcaa tctgagcggc gcagaattca tgaagatcat ttctatcatg agccctacta
     3661 cagatccagg caatcataat aaggattgac tgctaattat tcaaaagaca agaagttaaa
     3721 cttttacggg ggtgtgacaa aaatcggtca catccttttt ttcgaataaa cggtgttcta
     3781 aagccagttt ttcggtatta agtcaaattg cggaaaaagt gattttttaa acttctactg
     3841 gtctttgctt gtttccattt ataaaaaaat agcgaccctc aaaagtcaga tagagaatct
     3901 gacttttgag ggtcgcttta aaatcgcttc tttaagaata acatcaagaa tagcttcttt
     3961 tttctgctta atattccatt aatgtaatga tgtcatatcc tttgattttg tcgcgtccat
     4021 ggagatccat caattcgatc aaaaatgcgc agcctacgac tacaccgcct aattgttcga
     4081 tcagttcgat cgtcgctttg attgttcctc cagtagctag caaatcgtca caaatcagca
     4141 cacgttgacc tggtttaatg gcatccttat gcaatgtcaa tgtatctgtt ccatattcta
     4201 atccataagt cacttcgatg gtttctcgag gtaacttccc ttttttgcgg actggggcaa
     4261 aaccgactcc taactcataa gcaacaggac atcctacgat gaatccacgg gcttctggcc
     4321 caactaccat atcaattcgt ttttcttttg cataatttac gatttgttta gtagcttccc
     4381 gataagcgtc accatctgcc atcagtgggg aaatatctcg aaacacaatt ccttttgacg
     4441 gatagtcggg aatactggca atataatctt ttaaatccac tctttgtttc ctcctaggtt
     4501 gttaaccatt tctttatggt aggaatatcg ctcaaaagca aaaattcctc aactttgatt
     4561 ttattgagcc gtcgctggta taatctgctc tcagtcaaag gatgactttc tgggctagcg
     4621 actttttgta aaacaccgtt ctctattgta acaaatttca attcaaaaaa cacctgtatc
     4681 ataaaaatta ataatttttc agggatacgc aaatattgag ctattgcttt tattttatga
     4741 cgtatatcaa ttcgttcttg agaatggatc aatttaaaca attttgcgta ctgttctctt
     4801 gtgcctaccc cattcaaata ggcctcatca ggtgaaatcc ccatcagata aacacgattg
     4861 aatgaataag accgaaaaac ttctttcaga tccgctaaat catctggaca atccataaca
     4921 actagagagt ttggttttct tttttcaatt attgccttta cagaatctag tccttcgaaa
     4981 acaatcgcag cttcctggat aatctcaggc acgaatttca acgtcgaaga atcaaatgct
     5041 aaataaaggc taccttccga cgttcggctc tgttcacgga aacgttttgc ccgccaatca
     5101 aatacttgca gaccacccac agaaaaatca gataccatca gctgcggttt cttacgcccg
     5161 ttccattcat tgatcgaaag ctttcctacc acatctacct gattattcag cagttcttct
     5221 tcttgagtac caaaaccaaa agcgaccgca tcaagctgac tcgatgcatc ggaaaggaca
     5281 aatttcagat gctgttggtt tgctccgatt cttttgatat tttctgcttg gacttgtcga
     5341 aataaaaact gaggcaaagg attatccgta ccaaatggcg ccaatagttt cagctcatca
     5401 attcgctcta ctgttacttc atttggcagc aatacttcat caattctcaa ctcaggccct
     5461 ctcatcaagt caatttgatg atcgactata tattggttca tcttctcctg tagtatagtg
     5521 acattttcac ttggcatcgt taaaccgact gctgcatgat gtcctccgaa gtaagtaaat
     5581 aaatctcgca tctggtcaag catttcaaaa agattcaagg cttcaatact acgtccagat
     5641 cctttagctg atccatcttc ttttaaagta aggacaagcg ttggtttacc cgtttcattc
     5701 attattttcc cagcaacaat gcccaaaacg ccttcatgcc atcctcggtt taccaataga
     5761 tggatatgat tctccttatt gaccatcgct aatgcttctt gtgttatctg ctctacgatt
     5821 gcttttcttt cttcattgat ctcattcaat ttttttgctt gaacggatgc ttcctcttca
     5881 tcaaacgtcg caagtaacga gacggcagga cgtggatcgc ccatccgacc gattgcattt
     5941 agtctgggag caatcgaaaa accgatcgtt gtttcgtctg cgtccctcat ttttacgccg
     6001 ctttcttcaa atagcgcctg aagtcctatc cgttctgaat gatgaatggc atcgattcct
     6061 aatgaaacaa ggattcgatt ctcatcagtc aatgaaacta aatcggcgat cgttcctatc
     6121 gctactaaat ccaaaaattc tgcaggcggt tcttccaata atgcagaagc tactttgaat
     6181 gctactccga ctcctgccaa atctggaaat ggatagtgcc ccgctggatg acgagggtga
     6241 acaatcgcat aagcgtctgg taaattctca ggtagttcgt gatgatctgt aatgatcacg
     6301 tctacaccag cttgctgagc gtatgctacc gcatcatttc ctgctacccc gttatcaaca
     6361 gtgatgatca actggattcc ttcttcgatc ttttcttggt ataccgattg gtttggtcca
     6421 tacccatgct caaatcgatt tggcaggaat acttctactt ctgcaccaag taattccagt
     6481 gtttctttca ttaccgttgc actggtgatc ccatctgcgt cataatcacc gtaaacgagg
     6541 attttttctc cactgattac agcttcttgg attcggctga ttgctttatc catatcgtgt
     6601 atcagatacg gatcatgtaa ttcttgttcc tttggatgta aaaatcggtt gatatccttt
     6661 tcctcatggt aacctctttg ccacagtaac ttaccgacaa atggagataa tttcagttca
     6721 cggatcattt ggagaaagga ttcagaaggc tctgtctcgc ttaacttcca atcaaaattt
     6781 gcttgtctca ctttctcact cctaacttag ttattatagc aaaggaaatc agcaaaaaaa
     6841 agcagaaaga aagaataaaa acagatcaga tccgctagac agatgttcag caggacctga
     6901 tcttttgtac gaccatttat gaaatatccc tattagtcaa aataattgaa gctttgtttg
     6961 ggcgattgag ttttttgttc ttccggcgct ttcaattgac tgatttgtgc ggttttcgct
     7021 tgtaactccg cctgataagc agcttccaac tccgcacgtt cgtttctaaa ctcgcgttgc
     7081 tgttcttctt ttgcttcttc aattttcttt tgaagttctg tttgatattc tgacatttcc
     7141 tgagtcagct gtttgatttg ctttttttgc tgccatagtg ttgccgaagc agtcaaaaat
     7201 acaatcagtg caccaatcag cgcagaaccg atgatcacta agatcaatgg cgcagaaaag
     7261 gaagtgaagc caaaacttac aggaacattt ttattgttca atacagcaaa aagaacaata
     7321 atcaaaacta aaacaaatcc aagaatcaca ttgctttgct ttttcaattc cttcacctac
     7381 tttttgttaa aaattccgct ggctaaataa tcaccaatcg ttggaaacag cgtataaaat
     7441 tttgatgcaa cttctaaaat aaacggttga ttgatttccc gttttggatg tctcatattg
     7501 cggacgatca tttttgccaa cttggcaggt tctaaaacga tttgtccgac tttttccaaa
     7561 tagcttccgc ttggatcagc cttatcgaag aaatttgtct cgattggacc tggattcact
     7621 gtcgtaacag ctacgccaag tggtttcaat tctaatcgca aagcgttgga gaagccaagg
     7681 actgcaaatt tcgtggcaga ataaaccgtt gattttgcag ttgccatttt tccagccata
     7741 gaggcgatat taatgatatg accttgtctt ctttctgcca tatcgatcgc aaatttttgt
     7801 gtcaaaacca tcattcctaa gatgttgact tcaaacatat cgtatgcttt tccaaggtcg
     7861 aatgtaagga agtcttcgaa aatcccaaaa cccgcattgt ttaccagaat atcgacgcgc
     7921 ccgacttctt ccatcacctt ttcatataat tcgtccacgc tttcaggatt gctgacgtct
     7981 accttgaaag cataagcctc tttgccgctc aagcgtctgc actcgtctct gacaccttct
     8041 acaaatgcca ttcttcgtgc gcaacttata acgattgctc cttgctttgc tgcttcataa
     8101 cagatttgtg cgcccagacc gcctgaacta cctgttacta aaacaacttt atcttctaaa
     8161 ttcatgcctc ttcctcctcg cgaaatggaa tctcaatgct atcaaaatct ttcataatcg
     8221 tcgtgttttc aaacacttct tgtgcttctt tttcaagctc taaagctgct tttcctaaat
     8281 atctcgcact gatatgagta agtagcagcc gttttgcctg cgcttctttt gcaacttcag
     8341 cagcttgatg agtcgtggaa tggaaatagt tgtgcgccat tcttgcttca tctttattaa
     8401 atgtgctttc atgtaccaga atatcgctat tttccgcaag cacaacggaa ttatgtgttt
     8461 ttctcgtatc gcctaaaata gtcacgattc gtcctttttt atctggacct acgaaatctt
     8521 ttccattgat cgtccgccca tcttctagtt ggatcgtttc accttgcttc agtttgccgt
     8581 acagtggtcc agctggaata cctaattctt ttagacgatc cacctgcaat tctcctttat
     8641 gatcatgttc aaccacacga taaccaaaac tgtcgatccc atgatttagt ttttttgtat
     8701 aaacagaaaa ttgctgatca gtaaaaatcg gggctgtttc atttagctca atgaatttca
     8761 gcggataact taaacgcgtt tgcgaaatac ctaaagagac ttttatgtat tcctctatcc
     8821 cttttggccc gtaaatctct aatggcgtat ccccaccttg aaatgaccgg ctgctgatga
     8881 gcccgggaag tccaaaaata tgatcgccgt gtaaatgtgt aatgaaaatt ttaccgattt
     8941 ttctcggacg aatagtcgtt cgcaaaatct gcatttgcgt gccttcgcca cagtcgaaca
     9001 accaaacttc attgcgctcg tctaaaagtt tcaatgctat acttgtcaca tttctatgtt
     9061 ttgcaggaac acctgcacct gttcctaaaa attgtaattc cataatctac ctgactttct
     9121 ttaagttcct ctttaatttt agggtaaaaa gaagggataa tcaaccgtaa gtcgagaatg
     9181 ggttcaaatt aaaaataacg ttctaaagcg atagcgtttt ctttgaaaat tactataaaa
     9241 acagcagcga acccgtttga gatcctctgc tgttttttat taatttgaag atccagaact
     9301 ttcattgtcg ttggaagttt gcggatgttt gtccttccaa gtcttttgtg cagcttcttt
     9361 cgcatgattt tcagcttctt tcgcatcatg cacatctttt tcgacatctt cataatccaa
     9421 gcgagtaatt tctccgccta attccatcat taccaattga ttcagtgggc gattgtcctc
     9481 ttcatcagca atcaagatca gtcctgtagc tccttcaccg attttatttc ctacaaagtc
     9541 gaacacggtc tgggcatctt ttatttcttt ggcatcttgt gtcgcaccga tcattcctcc
     9601 ggcaaaccat cctaataaaa tccctagcgg accacctaat acaccaacca acattccgat
     9661 taatccaccc gtagaagatt tgttattacc ggtaaagtcg ataaaatctt ctattttgaa
     9721 ttgatgtgtc ccattaggat catggctgac aactgccatc tgttctcctt taatcgaacg
     9781 aacagcatgt aactttttga tttctgaaaa tgcctgatat gcctggcttt ctacttgaaa
     9841 atttaaaatg attactcgtt tgctcattaa aaacgcccct ttcatacctt cttgttattt
     9901 attttacctt taattgaaaa ataagaaaag aaaagcactc tttttttcca ataaaatagg
     9961 gctgtgacaa aagtcgtatc acagctcctt tttccgaata aacggcgttc ttgaagctga
    10021 tcacttctgt cacaacctcc cttaaatctg aatctatatt ttttggtatt tgtttttatt
    10081 tgcttgccta ttcgacaaat tcaaattcaa actcaccgat acgtacaagg tcgccatctt
    10141 tcgcaccgcg tgcccgaaga gcttcatcca cacccatacc acgtaattga cgagcaaaac
    10201 gcatcactgt ttcatcatga tcgaaattcg tcatttggaa taatttttcg atcttctcac
    10261 cagataagat ccacgttgca tctgaatcac gatcgatttg gaactcagga ccttctggat
    10321 tgaatccata gtgtacagtt tcttcttcca gttcttcttc gtacaatggg aattctggcg
    10381 ttacttctaa caaatctgct gtagcattca ataacgcgtc caatccttgt cgagtcactc
    10441 cagaaattgg aaatactggg atgtcatcag caaattcatc ttctttttcc ttgttcagct
    10501 gttctttgaa tttcactaga ttttccggtg catccggcat atccattttg tttgccacga
    10561 tgatttgcgg acgctctagc aagcgtaagt tataagtaga taattctttg ttgatggcaa
    10621 gatagtcttc ataaggatct cgtccttcca tcccactcat atcgatcaca tgtaaaatta
    10681 ctcgtgttct ttcgatatga cgaaggaatt gtgtacccag cccaacacct tgcgaagctc
    10741 cttcaatcaa gcctggcaag tctgctgcgg caaaacttct gccatcactt gtagtaacca
    10801 ttcctagatt aggtacgagc gtcgtgaaat gataagcgcc gatttttgga cgagcagatg
    10861 aaataacgga tagtaaagtc gatttcccga cagatggaaa acctacaagt ccaacgtctg
    10921 ccaatacttt caattctagt tcgatttttc gctcttgtcc tggttcaccg ttttcagcaa
    10981 tttccggtgc aggattccga ggagaggcaa aacggatatt ccctcgtcca ccgcgtccac
    11041 cttttgccac aactagtgtt tgaccatttt caattaaatc tcctaaaaga gcaccagtct
    11101 ccgcatctcg gacagtggtt ccttgtggta ctttaacata ggtatcttct gaaccacgac
    11161 cgtgcatccc tttactcatc ccattttcac ctggctgcgc tttgaaatgg cgattgaacc
    11221 gaaaatccat caatgtacgt aacccttcat cgacgatcaa gatgacatcg ccgccacgac
    11281 caccgtctcc gccagccggt ccgccgtcag gaacgtattt ttcgcgacga aatgcaacca
    11341 ttccgtctcc gcccttgcca gctttcacat cgatcgttac ttgatctaaa aacatggaca
    11401 taattaagtc ctcctattat tcatttattt atttgactgc ctgaatttcc acaataaaca
    11461 aaagtcttac ttattttatc ggtgaaatct gattttgtct atcatttcag caaaaagatt
    11521 gtttaccttc ttcttttttt atcatttggt aaggtttcca accttttttc tgctaccaag
    11581 tataattttt tgacaaaata ttctttgcgt agcagaataa cagtgtatta attgtattaa
    11641 ttgaggatgc cgtttcacag cacccctaat aaaggaggaa cttttgatat gacagtaaaa
    11701 gtaggtatta acggatttgg gcgtattggc cgtctggctt tccgccgcat caaagaagtc
    11761 tcagatgata ttgaagtagt agcaatcaac gacttaacaa gtccaactat gttagcacaa
    11821 ttattgcaat ttgactctac tcatggtact tatcctggca cagttactgc aacagaagac
    11881 tcaatcgtag tggatggcga agcaactcgt gtttatgcag aacccgacgc aagcaaaatc
    11941 ccttgggcaa aagaaaacgg tgtagatatc gtactagaat gtactggttt ttatacatct
    12001 gaagaaaaag caaaagcgca tttagatgct ggtgtcaaac gagtagttat ttctgcccca
    12061 gctggtgcta tgaaaaccat cgtctataac gtcaatgatg atacattaga tgaaaacgac
    12121 aaaatcatct cagcaggttc atgtacaaca aactgtttag cacctatggc ttatttctta
    12181 aataatgaat ttgggatcga agttggtaca atgacaacag ttcatgccta cacttccaca
    12241 caaatgctct tagatggacc tgtaaaaggc ggtaatttgc gtgctgctcg ttcagctgct
    12301 gacaatacta tcccacattc tactggtgct gcgaaagcaa tcggcttagt tatccctgag
    12361 ctacaaggaa aattacaagg acacgcacaa cgtgttccag tcgttgatgg ttcattaact
    12421 gaattggttt cagtattgaa aacaaaagta actgctgatc aagtaaacga agcaatcaaa
    12481 aaacacacag ttgacaatcc ttcattcggg tatgatgacc gtcaaatcgt ttctagcgat
    12541 gtcattggaa caactcaagg ttcgatcttt gacccaacgc aaacagaagt aacaactgct
    12601 ggtgatttcc aacttgttaa aactgttgca tggtatgaca atgagtatgg atttacttgc
    12661 caaatgattc gcttactaga aaaattcgct aacttgtaat ttgatagatc aatcgataaa
    12721 agaagccttt gactggatcc agtcaaaggc ttctttcttt tcatccccta cttttaaact
    12781 cgttcaatga acatattggc ttaaaaattg ttggactact tgctgatatt tttcaggatc
    12841 tgtcttgtat gcttccgcat gctcggctcc ttttacaaca tacttttctt ttggtccctt
    12901 cgttgcacga tagaccttat ctaacatttc aaatggtaca aatgtatctt cgtctccatg
    12961 tataaagagc attgggcgct ggtttttctt caattgttcc actgcatttg cttcaccgaa
    13021 aaagtagcca gcacggactt ttgtcactag actcgttact tgcataagcg gaaatgctgg
    13081 aagactaaac atatcgtcta gctgataagc aagctcatca tgaacggaag aataaccgca
    13141 atcttcaatg attgctttca cattatctgg tagtttttct ccgctagtca tcataactgt
    13201 tgctgctccc atgctgacac cgtatagaac gatttcttgc gattttccat tgttttctag
    13261 cactttgttt atccactgta catagtcttt acgctctggc catccaaatc caatgtaatc
    13321 cccttcgctt tttccatgtc ctcttgcatc aggaacaagg acattgtaac ccatatcatg
    13381 aaacatcttt gcgtaattgg tcatcgtttc agcgtttccc atatagccat gagccacaag
    13441 agctgttttt tcacttttcg tttcagcagg aagataaatc gctgataatt tcagaccgtc
    13501 ttttgaagtg atggtccaat cgcttcggtt ttcttttgaa ctaaaccatt tatgtgcatc
    13561 cgtttctttg gatgtctgtg ttgtaccagg tgtatcttcg tctaaaaagt ctttctcaga
    13621 aggcacaaca gcataattat aaaaataatt ccctgcaaac actaacgcaa caatcagagc
    13681 taaagcgacg cctaaaagga ttttcatcca aagtttcata aatcatccat ctcatttctc
    13741 ttttttcata taaccttgaa ttagtataat caaagaatct ctactatgca atgttcattt
    13801 ttataacccg cgaattgtaa aattaagtta gaaaaataaa aaggcattta tggtacactc
    13861 aaattgtatt tccgacgaaa gaaaacaaag gagtgta
//
LOCUS       DADQDV010000075        13682 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.078, whole genome shotgun sequence.
ACCESSION   DADQDV010000075 DADQDV010000000
VERSION     DADQDV010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13682
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.078"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(301..993)
                     /locus_tag="J8S10_002404"
     CDS             complement(301..993)
                     /locus_tag="J8S10_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAZ9630975.1"
                     /translation="MQIELQHTHDKETFEKNYKVYVELARDSAMKYGIPLTLDTPYNQ
                     PGIKSHLWVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDDNPTTSEDKPVIDP
                     TRAGAANSTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELAR
                     VRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVYVMMRATNDPEGNTKGGAQDF
                     HDKRWYLNIPQR"
     gene            1078..1254
                     /locus_tag="J8S10_002405"
                     /pseudo
     CDS             1078..1254
                     /locus_tag="J8S10_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348541.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
     gene            complement(1430..1999)
                     /locus_tag="J8S10_002406"
     CDS             complement(1430..1999)
                     /locus_tag="J8S10_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAZ9630976.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(2073..2396)
                     /locus_tag="J8S10_002407"
     CDS             complement(2073..2396)
                     /locus_tag="J8S10_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630977.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(2550..3362)
                     /locus_tag="J8S10_002408"
     CDS             complement(2550..3362)
                     /locus_tag="J8S10_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630978.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            3716..4564
                     /locus_tag="J8S10_002409"
     CDS             3716..4564
                     /locus_tag="J8S10_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HAZ9630979.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPIPVR"
     gene            4709..5650
                     /locus_tag="J8S10_002410"
     CDS             4709..5650
                     /locus_tag="J8S10_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HAZ9630980.1"
                     /translation="MELDFIKQLSKETFGYLYIAATRLSQKKYAGYFFHSKKENFFFT
                     SPSFTNRLPSNLCRKKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFR
                     KSAKREISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNR
                     IDWKLSAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPE
                     LLILGNRAFHGKDPGHTYFASLEAGDEKAFFAHLKKYAKKQIVLFVPENSPEVSEAIE
                     TLSKDRTVYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5640..7811
                     /locus_tag="J8S10_002411"
                     /pseudo
     CDS             5640..7811
                     /locus_tag="J8S10_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
     gene            complement(7923..10094)
                     /gene="copB"
                     /locus_tag="J8S10_002412"
     CDS             complement(7923..10094)
                     /gene="copB"
                     /locus_tag="J8S10_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HAZ9630981.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIR"
     gene            complement(10114..12300)
                     /locus_tag="J8S10_002413"
     CDS             complement(10114..12300)
                     /locus_tag="J8S10_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HAZ9630982.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGLIAVADQIKLEVKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLCLNRHMKK"
     gene            complement(12300..12509)
                     /gene="copZ"
                     /locus_tag="J8S10_002414"
     CDS             complement(12300..12509)
                     /gene="copZ"
                     /locus_tag="J8S10_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HAZ9630983.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(12522..12962)
                     /locus_tag="J8S10_002415"
     CDS             complement(12522..12962)
                     /locus_tag="J8S10_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HAZ9630984.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYYPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(13036..13575)
                     /locus_tag="J8S10_002416"
     CDS             complement(13036..13575)
                     /locus_tag="J8S10_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAZ9630985.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQLFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
BASE COUNT         3862 a         2850 c         2420 g         4550 t
ORIGIN      
        1 aactaatcac atataaaaat aaaaaaacat ttgtatttta tcaaagtttt attatacttg
       61 tcaatttgtg tacatcctaa aatataagct atttgtttac ttctgtagaa tatatacttt
      121 gttgttagat aagttgcaca tgtttataga atctaaataa taaattttta tgtaccgccc
      181 ctcaaagtga actgaacccc aaaagttgaa ctatttaatg gactgtttcc gatattctac
      241 tggagatagt ccattaaata gttcaacttt tggggttcag ttcaaagagg gggggatttt
      301 ttatcgttgt ggaatattta aataccaacg cttgtcatga aaatcttgtg ctccaccctt
      361 agtatttcct tctggatcgt ttgtcgcacg catcatgacg tatactttct tattagggaa
      421 atcacgcata ttgaaagata catgatagcc aacatttcct aaagtattat aagcttgatt
      481 tacgtctggt ctataaatcc catcagctct tactctagct agttcttttc cagtattgta
      541 gtccataatg aaaatatact cgtatttata attagcaatg tgccatccag ctacatgcaa
      601 gtttgcgttt tcgatttctc cgaactgatc aatgtgggcg taatttgttc catctgtcag
      661 cgtagaattt gcagcacctg ctcgagttgg atcaattact ggtttatcct ccgaagtagt
      721 tggattatca tccgtaaaac catgagccaa atcataggct agtttttctt tacttacacc
      781 catttcagaa agataaccgt aaggatctgt atgatcgccc caaatatttt gtgttaccca
      841 taaatgcgat ttgattcctg gttggttata aggagtgtct aatgttaatg gaataccata
      901 tttcattgct gaatctcttg ccaattcaac gtatacttta tagttctttt caaaagtttc
      961 tttatcatgt gtatgttgta actcgatttg cacaggactt ttggctcacg aggttgtcct
     1021 actctacatc ttgctgatag atatgctgaa aggaaaacac caacattatg ttttgctttt
     1081 tcagctagaa cgagacaagc aggaatacct ttagaagata tcaaaggttt tttaggtcat
     1141 aaagatgttt ccactacaca agtctatgcc catatttctc ccgaagtgaa aaaaagatca
     1201 atgaatcaac tagaaaacta tatagaagag caaataaaaa agcactcaaa ttgagtgctt
     1261 ttttaagctc actatcacta aaactatcac taattttatt tataagcgaa catgtttcta
     1321 tcactgattt tttaaatcta gcgaaaaacc cttatcttaa aggcgttcgt tcaattcttt
     1381 ggcaaggtct tcaaagcctg gcttgcctag aagtgcgaac atggttttct tatagctcat
     1441 gtagaaaaat tttcttgatg atgattttat ccatcaattg agattgactg ttttgctctc
     1501 ctatgatttc agctatgatt gtccgatttt gcggttttct tcttaactgg tagttgattt
     1561 tcccagtttc catcaactcg ctaagcatat ccacgactcc gccaaatccg gtctttttcg
     1621 taataaaacc tagtgctacc attcgttcat ctagattttt tgctgtaatc gtcacaccag
     1681 taatgagcga gtgctgtaat gtttgggcca gctcttccat cccttcagca ttggatacga
     1741 cggaagctgt tttgttaata ggttcttcgt ttatttcttt tggttctttc ctctccactt
     1801 tcactgtttg acgaaggaca tctagttctt gcaagagcgt ttcgtattgt tcttgggtca
     1861 gcatcacgcc agctactttt tcacgattaa atatatatac gccagttccc gcgtctcgcg
     1921 cttgagcaaa tacatccatc ggcgatcgtt tcacttctgt gatcgaagat gtgggaactt
     1981 ctaatttctt taattccaat ggatttcctc ctttactaat cgctttttat tatagcacag
     2041 actgacttgt tttgatcttt tttccaaagg ttttatcggt ttttgcctaa ccagtaattg
     2101 atatcggtaa gaagtctttc gataccaaat gaaggatggt acagatacgt tttttgatct
     2161 tcgttatggt ctagtggaaa aaaatgatcg atgatcacta gatctgcata ccgaggcggc
     2221 ttatttcgag tacatacatg tatagagatc cgttttcgat gtcttagcgt tttgttcagt
     2281 accccagcaa gtcttcttgc ttcttggtgt tcatagcgaa aaaaaaagac gattttcact
     2341 tcaggagggt ggacatctaa ataccctcgt tcctggagtg ttttcagtaa aagcatcccc
     2401 cactctactg cggggtgtgc aagtgcttgt tggatcgcta gccgaaattg atatagttta
     2461 tctttggaat tgggaaattt ttctaatgtt tcctgataat aacgaacttc ttctatcagc
     2521 cggtcatgga taccaattac gtaacgaagt cattcttggt aaagtacttt tgtcagcttt
     2581 gatttgcttt cgctctcaaa ttcgctattc agccaaaaca gcgaatcaag cttttcagtc
     2641 acaatcgtca atttccgata gtcttgtgtc tcttctatcc gtttccaccg cttttcagta
     2701 atctggttac agctcaagcg caaaattgct agataatttt tttcttttat tggcaaaatc
     2761 tgctcctctc taaatagcaa ttcaggaaac aattcaaaga atagtgttcg actgtctcct
     2821 aaaatctcga tttctgccgg atcctttctt tgcttcaata attggatgaa catctcagaa
     2881 aaggactgct ctccatcatc tgcaaaaaaa tgcggaaaat ctttcaaaaa gcaaaacagc
     2941 agatatctta cttttctttc tgaaccaaag atctgtgctt ttttataaga aaaagaaagg
     3001 tggtactcgc caaaccactt tctcaatcgc tcttgcgtag aacgatcgta cttctgctcg
     3061 taaggttcat tcaatagcag atttttcagt aaacaaaacg ggggtgattg gatcagaaaa
     3121 acaaacaaga gataaggttc gctatatcct tgatcataaa ctaactgaac ggttttctta
     3181 tgaagaatca gctgaatggg acagtcgctt tccgccaaac gtttcagatg ccgatccact
     3241 gttttaacat cgattttcag ttcttcagct aaatcagctt ttcgccagat caaatctttc
     3301 attagattga ttagtgaaaa taaattctgt gcattttttg ataatagttt ttgccatctc
     3361 atcgatcatt tctcacctga tttctaaaca tattgtttga tcaaaatggg ttcactccta
     3421 aaaagataaa aaactccctt tctatttatt taaatacgca aatcttcctc attatttttt
     3481 attttactca atttaatcgt attctcattt caaaacgaat gtactttaaa aaaacataat
     3541 aagatcactt tgcttgtagg atgtattccc ttccattaca atgaaataaa tagcgatttt
     3601 atgagaaggt gatgtgaaaa tggaagaaaa aatagaagaa tccaaacaaa aaatcgatca
     3661 gttgatataa gaattagaaa aagcggtcat cggcaaacgt tcaactatcc aattgatgat
     3721 cgtggcccta ttagcaggtg gtcatgtctt attcgaagat attcccggtg taggtaaaac
     3781 gttactggtc aaagcactag caaaagctgt acagggaacc ttcagcagag tccaatgtac
     3841 tcctgatctg ctgcctagtg atattcttgg tttttccgta tacaattcac aatcaaaaga
     3901 gtttgaattt cgtccgggac cgatctttac cacgatcttg ttagcagatg agatcaatcg
     3961 tacgactcct cgtactcagt cagcactttt agaagcaatg gccgagaatc atgcaacgat
     4021 cgacaacaat acataccctc tagacaatca tttttttgtc ttagctacgc aaaatccaat
     4081 cgagtacgaa ggaacatatc ctttgccgga agcacagctc gatcgttttt tattccgact
     4141 acaaatcggt tatccttctt ttgatgacga acttttgcta cttttggata aattcgaaaa
     4201 agtgttggat aacttaaatg aagtattgaa cagttatgaa atagaagaaa taaaaacaaa
     4261 tgtggcgaat gtctttgtca gtcccgaagt ggcatcttat gccttgcagt tagtgtcagc
     4321 aacaagaagt catgctgcca tccagcttgg catcagtcca cgaggaagcc tttcctttat
     4381 tcaggcagca aaagcttatg ctttaatcca tgggagaaat tacgtcacgc ccaaagattt
     4441 gcaggattta gttccttacg tgttttccca tcgcctgatt ttttacgatc gttcattgaa
     4501 ggaagacgaa aagaaacaaa tcattcatac tcttgttgca caaattccta ttcctgtgag
     4561 gtagattgag gtagacaatg gaaaaaatca aagattattt cattaatttt gtgttatttc
     4621 tggtatattt catcattgtg ctttttgctc ttgtattcaa caattcttta ggctggttct
     4681 tgttggcctt ttttactctt tatgtatcat ggagcttgat ttcattaagc agctttctaa
     4741 agaaactttc ggttacttgt acattgcagc cactcgttta tcgcaaaaaa agtatgcagg
     4801 ttattttttc catagcaaaa aagagaactt tttctttacc tctccctcgt ttacaaatcg
     4861 gcttcccagc aatctttgca gaaaaaaaca agagattttg attcttacaa ataaaccgca
     4921 agaagtccaa ttgctttggc agccaaaaga aagaggatgc catgaaacat taactgtcat
     4981 ttttacagcc tatgatagtc taggactttt cagaaaaagt gcaaaaagag agatctcttt
     5041 tcctgtgact gttctgcctg ctttttgtaa gattcaagca gaaaaattac agagagttct
     5101 ggaaaaaaaa cagcagctga acgcgtacca aagaggtctt gattttcggg aacatcgcgc
     5161 ttatcgtcca ggtgattctt tcaaccgaat cgattggaaa ttgtctgctc atactcaaga
     5221 gtggttatac cgtgaatacg attatcaaga agaagaatgt tctcctcttt tttgcttttg
     5281 gggttcgccc agtccaaaat ttgaacctct gctagacttg tatttttctt tatggcattt
     5341 gagaaaagaa aagcagccgg aacttctgat attaggcaac cgcgcctttc atggcaaaga
     5401 ccccggtcat acctattttg cttctttgga agctggcgat gagaaagctt ttttcgcaca
     5461 cttgaaaaaa tatgcaaaaa aacaaatcgt cctctttgtt cctgagaatt ctcctgaagt
     5521 ctcagaagct attgaaacat tgtcaaaaga tcgaacggtt tatcttgttt atttcgtaga
     5581 aaaacaactc atggtccaag aaaaagacaa gatatgttca ttgccaggag gtgaatggat
     5641 tgacgattaa acgggaaaaa tggctgcgtg gcgtttactc ctttgtgata ctaagtgtag
     5701 gtgctccgat atttgtagta gctaatcaat tgcaaaacag ctaccttctt atcctaacta
     5761 ttggtgtcct atgccttatt gtctgctgta ttcctaaaaa atgggtacgt ttgctgcttt
     5821 ctttgccagt aatgataggt tgtttgtttt tatattttcc ttcgaagaca ttttccatat
     5881 tatggatctt acagtttttt tcgtcagtca cagaggaatt cttccatcta tcccaaggta
     5941 aactttatta tttgccagaa aagacagctt tttttctcat aatgttgctg atctatttat
     6001 ttattacatt gaccgtggat tacgactatt ggtacgcacc ctttctttct ttgatggctt
     6061 acttcatgat gcttaccgtt tttcggaaaa aagatttact gtacgaaatg attgcggtag
     6121 taactgtttt gttcgtgtat ctggcagcaa ggcaattttt ctccatccgg ttgttgtcgg
     6181 gaaacactcg attccagtca ttgactacag ttctgcttat ttgtttctta acttttagcg
     6241 ctatcttgcc tttatatctt ccgaaagtac accaatctct cgaggaaacg agtgaaccga
     6301 tccgagaata tcttaatgat gaagggcttt atgacacact ccatgagtat caattaaccg
     6361 gaagtgcaag aacaggcttc agtgagaatg atgaacagct tggtggacct ttatatgata
     6421 atggcgaagt tgtttttaca gcgaaccaaa aaggaaatgg ctattggaag atcgaaaata
     6481 aaaatcatta caccggttct ggatggatag aagatcagga cgcacccatc caaccaatcc
     6541 aagaattccc tgttgacatc acgagctacc aaaccgttat agaagacaaa gaaaacatta
     6601 cattgaccct aaaaaaacaa gttttcttac cttatcctta tggaaatact accttgactg
     6661 atttttcatt agctagtgga caaacgcttt actatttgcc tgaaagccag cgattcattc
     6721 ctgtcccgaa tgaatcgaca cgttctgcaa ctttacaaac agaaaggtta gtttttacga
     6781 gagaagaatt aaaaagcagt cagttaaaag ctgatgattt agaaaatcag cagacaaatc
     6841 ttcaattgcc aaaaagtttg cctaaacgta ttgaggactt ggcggtcgaa ttgaccaaaa
     6901 atgaagcaac tttaattcgt aaagtcgaag ctgtctaaca gtatttaaaa acaagcggaa
     6961 atttccgcta ttccaaaacg gataccgggc atactccaaa agaacacgat tatgtggatt
     7021 atttcctctt tgattcaaaa gtcggctatt gtgacaactt ttcaacttct atggtcgtcc
     7081 ttcttcgaac acttggtatc ccagctcgct ggacaaaagg ttttacaaat gggctcagaa
     7141 caggcacaga taatcaaggg aatgaggaat acagcattct caatagtcat gctcattctt
     7201 ggccagaggt atactttcct ggatttggct ggcttccatt tgaaccaacc ccttcatttg
     7261 ccaatccaat gggttcacaa ccagttgctg aaacaaccga aaccgtccag cctgctatcg
     7321 aacaaccaaa tgaaagcgaa aatatggcag aaactatttc cagtgagaga tctgaggtca
     7381 ttccatcaga agaaacaaca ctcacaccag cttataaaat cgtcttattc agccttggag
     7441 tgtgtttatc cgtcttgttg ttctttctat tgttattcag aaaatctctg cgctggacaa
     7501 gttatcttat ctatcttcat ttttttgctt ctactaatac gattgcatat caaaaacttc
     7561 ttaacccttt ggaaacattg gtaccgcgca aacccgcaga atctttgcag gaatatagcc
     7621 tgcgaataga acaagaattc aagctagatc tgcgtttcat tcgattaact actcaatatg
     7681 aagcagaaat atatggacga caagcagatc cggtaaaatt cgataaaaaa acctatttag
     7741 aaataacgca tataataaga aaaatggtat acaaaaaaat tctgacaaaa gggagccgct
     7801 tcaaaaaata agataaaatt tctggagaat ctacttctgg aatgccgaga accagctgat
     7861 tgagtatcga ttactcgaaa aaaaggttgt gacacgtttt ttgtcacaac cttttttcat
     7921 tattatctga ttttcaatgt caaagcattt agagctacaa ctaccgtact taacgacatc
     7981 aagacagcac caactgctgg acttaatatg ataccaattg gcgcaagaat tccggctgct
     8041 agcggaattg caagaatatt gtaacctgcc ccccaccaga ggttctggat cattttcttt
     8101 cgcgtttgct tggctagatc aagaaaatgc aaaatatctt ttggatcgct gtttgtcaat
     8161 acgacatccg cagaatcgat tgcgatatct gtccctgcac cgattgccat cccgattgaa
     8221 gcacgggcta aacttggcgc atcattgatc ccatcaccca ccatgattac ttttttccct
     8281 tggtcaaggt atttctggac aacagcttct ttatcatctg gtaataaacc gccataatat
     8341 tcttcgatcc ctaaataatc tgctactgct tgggcagcgt ttttattgtc accagtaagc
     8401 atgacaggag tgatttttct ttctttcaat gttcggataa attcttttgc ttctgttttt
     8461 actacgtcac ctaaagcaac gattgcagct agatgatttt ctaaaatcag gaagctgatg
     8521 gtatttcctt gttcttggta aggtttcaat aatgcttgtt ctacgtttaa tccgagacgc
     8581 tcaacttctt tttcattaac tattttcact tgttgttttt tgactgttgc ctctagcccg
     8641 actcctgaaa gattttttag attttcagct tgataaggct tgatttcatg ttctttcaaa
     8701 taattcataa tgccaacagc caatggatga ttggcattcg cttccaaggc tcctagatat
     8761 tgaaggattt catttttatt gaacgcatca tcaagtactt cgacacccgt tacagtaaat
     8821 tttccttctg ttagtgttcc tgttttgtcc agcatgatca catctagatc attggcttgc
     8881 tccagtgcat tgcggttttt caaaagtaat ccgtttttag ctgctattga tgtggaacga
     8941 gcaacaacta atgggatagc taaacctaga gcatgaggac aggcgatgat aaagactgtt
     9001 accatacgtt ctaatgcatt aggaagatct gtcaagaaca accaggcgat gaatgccagg
     9061 atacccacaa ttaatgcgac ataaaacagc cattttgcca ctttgtcaga taatgactct
     9121 agcttggatt tttctccttg tgcttttcgc accatttcca taaccttcgc tagataacca
     9181 ttttcaccag ttccagttac ttcgatttcg atcgttccat ccccattgat agaaccgcca
     9241 atcactttgt cattggcttg ttttttgatt cctcttgatt cgccagtcac agctgattcg
     9301 tcaacaattg tttcaccttt caagattaca ccatctgttg gcattttatc accagaccgg
     9361 acgatcaaac gatcaccttc gtttacttct ttcaatgaaa ctgtctcttc ttttccatct
     9421 ttcgtcaagc gtttcactga ttctggcagt aattctgcta gtttttgtaa agcattgctg
     9481 gcattcgaca cagcattcat ttcaatccag tgacctagta gcataataac gatcaaagta
     9541 gccaattccc agaagaaatc catgacgtgt gtatgtggat tgagcagatt tgcgataaac
     9601 gaatagacac tataaatata tgcaactgta atccccatcg cgatcagtgt catcatagca
     9661 ggactttttt gtttcaattc catcttagct ccacttaaaa atggctgacc gccatagata
     9721 aatagtatag ttgctaagat caatacgagc caatcagaac caggaaacgt tacttgaaat
     9781 ggaaattcca ttcccatcat tggtgaaaaa agaatgattg ggatagctag gataagcgat
     9841 agccaaaatt tttgtttgaa attccccatg tgcatggaat gatccatgcc gccgtgttcg
     9901 tgatccatgt gcatcgaatg gtccatttgt ttgctgtttg ctatatctcc atggttatgt
     9961 cccatgtgca tggaatgatc catctgacta tggtcatgtt tcatctccat ctgtttttca
    10021 tgagattctg tactttcttt gtttactact tcttttttat gctcatgttt tttctccata
    10081 tcgttcccat tcatttttac tccatccctt ctcttacttt ttcatgtgtc gatttaagca
    10141 cagggagttc aacaatacac tgacggaact aaacgccatc gctcctcctg caatgattgg
    10201 attcaaaaag cctagtgcgg caaaaggaat accaatcgta ttatagacaa aagcccagaa
    10261 aagattttgt ttgatttttc tcaatgtcaa cctagacaac tcgattgttt gtgcaatgga
    10321 tgccaaactg ctattcatca gcgtcacatc ggctgtttcc atcgcaatgt ccgttccact
    10381 tcccattgcc ataccgacat cagctaatgc taaggccggt gcatcattga ttccatcgcc
    10441 tgccataccg acttttttgc catctttctg aagtttttct acgtaggctg ctttatcctc
    10501 tggaagtact tcagcaaaga tatgctttgg atcaatacca acttgtttac caatcgtttc
    10561 ggctgccagt ttgttgtctc ctgtcagcat aaaaacatct aatcctttat tctggagctg
    10621 cttgattgct tgtttgactt ctagtttgat ttgatcagcc acggcaatca acccgatcac
    10681 ttgcttttca tcagctaaaa acatgactgt ttttccctgc tgttctaatt ctaacgcgtg
    10741 ttcttggtat tcatcaaatg ataggttcaa ttcaattaat cgtttacgtg tacccgcaaa
    10801 atagcgtact ccgttaatcg taccgctgat tccagcacct gggtgggctg taaaatcaat
    10861 catatcgtat gttgctgctt cttgcagttt tccgtattcc acgattgctt tacctagtgg
    10921 atgttcagaa gcttgttcta aagtataaaa aatagatagg acttctttag aaccgactag
    10981 atctgtaact ttgggctttc cttctgtaat cgttccagtt ttatccaaaa caatgctgtc
    11041 taagtgagca gctgcttcta atgcttctcc gcctttaatt aaaattccat ttcgtgcacc
    11101 aacacccgtt cctaccataa tagctgttgg agtcgctaaa cctaatgcac atggacacgc
    11161 aatgactaat acagagacac tatggatcaa tgcgagttgc caatcaccag tgatcaaacc
    11221 tgtagctatg agcgtgataa acgcgatgac taatacgatc ggaacaaaaa tccctgagat
    11281 ccgatctgcg attttttgga ttggggcttt gctcccttga gcatcttcca ccatttgaat
    11341 gatttgcgct aatactgtct gcttgccgac ttgtgtaact tccatgtgaa gtagaccatt
    11401 cgtattgatt gtcccgccaa agagcgtgtc atccggattc ttttctacag gaagattttc
    11461 accagtaagc atactttcat ctatcgcact gcttcctgaa ataattcgac catctgctgg
    11521 aatctgctca ccaggacgga tgactagttg atcaccaacg actacttctt caatcgctaa
    11581 cgtttcttct ttcccgtttc ttatcacttg ggcggttttt gtttgaagag acatcaattg
    11641 tttgattgca ttacctgttt tcgtttttgc tgtatgttcc aaatatttgc cgagcaaaat
    11701 cagcgtgatg atcatactgc tgctttcaaa ataaagatct tgggggtgtc cacggaaaaa
    11761 tccgttgtaa atgctcaatg caaaggcagc cgatgttcca attgctacca atacatccat
    11821 atttggtgct ttcgtcttga ttgcatggta cgcaccttta taaaaacgag caccgacata
    11881 aaattggaca ggagcagaca gcactaactg gacgattgga aaatgaaaaa agtgaacaat
    11941 cgccgcatgg cttcctaaca tcatagcaat cattgacaac atcaacggca aagtcaaaac
    12001 cgtactcaat ataagatcga atagcatttt tttcaaatac gcttgctttt cttctgcaat
    12061 tttttgtttg tgggcttcat cgtacaaaat tgcaccatag ccgatgtttt ctacgctttg
    12121 gattaatttt tcagtggtcg tcccttcata tttgacactt gctttttcag tggccaagtt
    12181 gactgtggca ttgaccacac caggttgtcc gttcagctct ttttcgatcc tagcagaaca
    12241 atttgcacaa gtcatacctg taatgacgaa cgtatccatt ttggtttctg ctgttgccat
    12301 caaatcacct ctgctttata acccaatcca ttgattgctt gacaaatctt ttcggattga
    12361 acttttgttt catcaaactt gaccgtaccg tttgcttttt tcaaatttac tttcactttt
    12421 tgcacgccgt caagtgcgct tactgtttct tctactcttg ctgcacaatg attgcagctc
    12481 ataccttcga ttgaaaattg ttgtttcatt ttttcttcct cctattgatg ttgtttacat
    12541 tcacattgac ctgggataca gttacattcg atcgtatcta ctggttgctt ttgttccagt
    12601 tgtttcaaaa tctcattgat atcttcttga gtcaaagtgg cttcttctac tagatccgca
    12661 atcgtctctc caatcctttt tgcacagata tgggaaaaaa gattttccgt cgcactgcga
    12721 actgtttcca tctccgagac agctggataa taaatgaatt tttttccttc ttgttctgtc
    12781 cagatcactt ctttttttac caaacgaccc agcaaagttt tgatcgttgc tggtttccaa
    12841 tccatcgaat cagctaagat ctgcgtgatt tcttgggctg tcgtctgtcc aagtgtccaa
    12901 ataacacgca tgatctccca ctctgaatca ctgatcttta ctggcgtttt gactttttcc
    12961 atttatttca cacctttcgt ttacaaatgt aatcattatc ttatgaatac agattacact
    13021 tgtaaacaaa aactgtcaat tatttttgct ctctattttc aatttagtta aaaattcttg
    13081 tttctctcgt cttgttttaa ggatgatcag tttatttctt gcattagcta cttggatcag
    13141 ctgctgtatt ttcggttcat tgttttcttc aaaatgccag ataaaagata aaaattctaa
    13201 gtattccctg tttagtttct ccgaaaatga ttcaggcata tctggccgag attttttgtt
    13261 tatctttctt tttagagaac gccaaactac tcggtagatg gcgagataac gcggcacttt
    13321 aagccaaatg atcttatctg cttctttaat cctttcctct aatgtagaag tataatttcc
    13381 ttcaacgatc catgacggat tagataccat aaacaattgc tgttcttgca aaaaccactt
    13441 ttttgcctga atactgtagt ctgttgtatg ccataaaagg tctagcggca gtagcggaaa
    13501 gtcggtgatt tctttgatct tccttgcgag ggtcgatttt cccgacccac tttgtccaat
    13561 cacgatgatc ttcattcttc tccctcactt ctctttggaa tttggttcga tcataccact
    13621 tataacgccg caaaaaaaca agggactgtg acaaaagtcg tgtcaaagtc ccttgtttcg
    13681 aa
//
LOCUS       DADQDV010000076        12982 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.079, whole genome shotgun sequence.
ACCESSION   DADQDV010000076 DADQDV010000000
VERSION     DADQDV010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12982)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12982)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12982
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.079"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(538..900)
                     /locus_tag="J8S10_002417"
     CDS             complement(538..900)
                     /locus_tag="J8S10_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630986.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
     gene            complement(974..1354)
                     /locus_tag="J8S10_002418"
     CDS             complement(974..1354)
                     /locus_tag="J8S10_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HAZ9630987.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            1436..2611
                     /locus_tag="J8S10_002419"
     CDS             1436..2611
                     /locus_tag="J8S10_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAZ9630988.1"
                     /translation="MIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADMDFLSPG
                     GVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVLTSLAAA
                     VQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDMEKKIEEN
                     NVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHTFTSMLT
                     IDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEINTFGLI
                     GTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLDFTAYIS
                     DDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYALETID"
     gene            complement(2688..3272)
                     /locus_tag="J8S10_002420"
     CDS             complement(2688..3272)
                     /locus_tag="J8S10_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAZ9630989.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            3473..4471
                     /locus_tag="J8S10_002421"
     CDS             3473..4471
                     /locus_tag="J8S10_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAZ9630990.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            4583..5092
                     /locus_tag="J8S10_002422"
     CDS             4583..5092
                     /locus_tag="J8S10_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HAZ9630991.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(5122..5781)
                     /locus_tag="J8S10_002423"
     CDS             complement(5122..5781)
                     /locus_tag="J8S10_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HAZ9630992.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(5783..6547)
                     /locus_tag="J8S10_002424"
     CDS             complement(5783..6547)
                     /locus_tag="J8S10_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HAZ9630993.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(6555..7232)
                     /locus_tag="J8S10_002425"
     CDS             complement(6555..7232)
                     /locus_tag="J8S10_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HAZ9630994.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(7269..8654)
                     /locus_tag="J8S10_002426"
     CDS             complement(7269..8654)
                     /locus_tag="J8S10_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HAZ9630995.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(8864..8948)
                     /gene="ffs"
                     /locus_tag="J8S10_002427"
     ncRNA           complement(8864..8948)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="J8S10_002427"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(8971..9486)
                     /gene="tadA"
                     /locus_tag="J8S10_002428"
     CDS             complement(8971..9486)
                     /gene="tadA"
                     /locus_tag="J8S10_002428"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HAZ9630996.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            9593..10450
                     /locus_tag="J8S10_002429"
     CDS             9593..10450
                     /locus_tag="J8S10_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fis family transcriptional regulator"
                     /protein_id="HAZ9630997.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(10531..10866)
                     /locus_tag="J8S10_002430"
     CDS             complement(10531..10866)
                     /locus_tag="J8S10_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9630998.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(10933..12303)
                     /locus_tag="J8S10_002431"
     CDS             complement(10933..12303)
                     /locus_tag="J8S10_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NOL1/NOP2/sun family putative RNA methylase"
                     /protein_id="HAZ9630999.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(12381..12917)
                     /locus_tag="J8S10_002432"
     CDS             complement(12381..12917)
                     /locus_tag="J8S10_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAZ9631000.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
BASE COUNT         3858 a         2622 c         2154 g         4348 t
ORIGIN      
        1 cccgattcgt ttttggctgc cgtagcaact tttatatcat atcagagaga caagtaattg
       61 tcaactcttt tttaaaagtt tttttgattt cgtttttcga aatctttcag caactcattt
      121 atcataactt atcgtttgtt atttgtcaag aacttttttg aagttttttt cgatagaatc
      181 aagcttcgca agtggttctt ttttaacgac tcagttatct tatcatgtcg ttagtaacat
      241 gtcaataact attttttaaa ttttttagaa atgtgatata acatccactt cagaatcaac
      301 gctgttaaat ttatcatgta tttcttcctt ggtcaactat aaattaagca ttactttgtg
      361 aaatgatttt tcgatcaatt attattattc gttatacaac cgttttcaac atattttgaa
      421 aataaaatgc actaaaaaac tatctttagc agaacatttc attgtatttt ttggaccaaa
      481 caataaaaaa agaagtttga aaaaaattca aacttctttg ttcgcttaat ctgtatttta
      541 gaagaaaggc actccctcta cttcgtaagt tccaagaaca gagcgcattt gacctggttc
      601 ttcccaaata tatccttcgc ctaattcttc tctttgattc ttttgttcag tttcaaagac
      661 aaacaacgga acattttcct ctttaatatg tgtatttgtc aattccatca aactaatctt
      721 gctaacatcg atatgaacta tttcttttaa gaaattaagt atattcgcta aaccagtctt
      781 tccttcagaa agttccgcta acgcaaattc caacttgtca tcaattgaat ggaccaaaaa
      841 ttttttagta ccatcctcca aatgcaacat aattgtacca gcaactcttt tgcttgccaa
      901 aatttccacc tcgatcaact tgttctatgg cttacataaa aattctagca cattttcaga
      961 aaaaatacac tttttatttc ttattttctt tccgttctag ttcagataat gcttcttcta
     1021 tccaaatagg taactgctcc gcaatagtgg taaatccgat cttacgattt ttattcgtga
     1081 aatacctttt tctgcgatat ggaacagctg gatttgtttt ttctaacgtt cttaaagata
     1141 aactgatttt tttggaatat tcatcaatgt cgatgatctg aactgttact ggctgtccga
     1201 cttttaacaa tgaatggata tttttcgtat aaccggattg tacttctgaa acatgaataa
     1261 gtccttgcgt ctcgttatca agagaaacga atgcgccata aggctgtatc cctgtcactt
     1321 ttccttcaat tatttgtcca attttataag tcatctactt ccctctcttc gcatttatca
     1381 ttatactgta aatagctcaa aaaaagaagc gacgaaaatg actggaggtc ttaagatgat
     1441 cgaatttgat aaacagattt caagaaaaga tacagaaagt gtaaaatggg acgcaattgc
     1501 tgagacatat caaatggatg acttacttcc tttgtgggta gcagatatgg acttcttgtc
     1561 tcccggtggg gtagctaaag cgtttagtga atacatcaaa catggaatct ttggttatgc
     1621 cactctgtct gataaactat atcaggctat cattcattgg gaacgccaac accatgctgt
     1681 ggagttgacg aaagaaaata tcgtttttac aagtggtgtg ttaaccagtt tagctgcagc
     1741 agtacaaact tttacaaaac caggcgattc tattttgatt catgacccag tttatcctcc
     1801 attttcctct attatagaaa caaatcaacg tcacatcgtt cgaagctctt tgctagaaaa
     1861 aaataatcat ttcatcatgg acttgtctga catggagaaa aaaatcgaag aaaacaatgt
     1921 aaaagcaatg attttatgca atcctcacaa tcctggaggg cgtgtttgga gcaaagaaga
     1981 attgaaacag ttaagcgaat tgtgtttaaa acatcaagtg attctgttta gtgacgagat
     2041 ccatcaagat ttaactttat tcgatcatac atttacttcc atgctaacga ttgatcctaa
     2101 tttagatgat ctactagttg cttttacttc cgcaaccaag actttcaatc tagctgcaat
     2161 caaaaattca atggtattta tcaaaaatcc agagatgaaa gctgattttg aaaaacattt
     2221 agtgatgaac caacagcacg aaatcaacac ttttggactg attggaaccc aagcggctta
     2281 tgagacgggt ggagaatggt taagccaact gattccttat ctagaaaaaa atgttcaaac
     2341 agttaatcag ttttttgaac agtatcttcc gaaagtgaga ataatgaacc ctgaaggaac
     2401 ttacttaatg tggttagatt ttaccgccta tatttcagac gaccaagaat tggagaacac
     2461 tcttgttcgg aaaggaaaag tcgtattaaa tcctggcatc acgtttggtc cttccggtca
     2521 tgggcatatg cgcttgaata ttgcttgtcc agaagaaact ttactggaag gacttaatcg
     2581 aatcaagtat gctttagaga caatcgatta aatcatttat tcaaaataaa aggacgagac
     2641 cttactaggt ttcgtccttt ttcataatta ctccgtacca taccaaacta ttctgaaatt
     2701 tcaattgttt caatcactac atcatgtaca ggtcggtctt gtggaccacg ttgtacattt
     2761 gcgatttcat ctactgtgtc catcccttct agtacatgtc caaagactgt atgtcggaaa
     2821 tctagccaag gagttccgcc acctttatac gcttcaatga tttctgatgg gaatccagca
     2881 ccttctagtt gtccaagcat attagctggc acatttgtgt tatttacaat aaagaattgg
     2941 cttccgtttg tgtttggacc tgaatttgcc atagataaag ctccgcgaag gttgaacagt
     3001 tcacgactga attcatcttc aaaactttcg ccataaatac tttcgccacc cattcctgtt
     3061 ccagttggat cgccgccttg gatcatgaaa tcaggaataa cgcggtgaaa aatcacgcca
     3121 tcataataac cttttttgga aagttcaatg aaattttgaa ccgtcttcgg tgctagttca
     3181 gggaataatt gaacagtaat gtcaccacgg tttgttttga taacagcttt tggtcctttt
     3241 tcacttttta aatctagttg tgggaatgcc atattgtttc ctcctaatat ttgcatactt
     3301 cataataata ataacataat acctaacctc tcgtaaaaat actagatttg ttttctttta
     3361 tttttcatca ctagatacat tctataactt accgtttcga tttcgaattc aaacattttt
     3421 gagaagcatt ctcaattaaa ttctgatata gtgtgaaaag ggaggaattt ttatggaaat
     3481 ctatgacatt acaatcatcg gtgcaggtcc tgtagggatg tttgccgctt tttacgcagg
     3541 aatgcgccaa gctaaaacaa aaatcattga cagtctacct caacttggtg gtcaattagc
     3601 aactttgtat cccgaaaaat atatttacga tattcctggg tatccagcaa taaaagcaag
     3661 tgaattaatc gatcaattag aaaaacaatt aactactttt aaccatacat tccatttaaa
     3721 agaagaagtt ctctcgctta ctcgtgaaga cgaagttatc gagattacta caaataaagg
     3781 catccattat tccaaagcag tcattttagc tttaggaaat ggttcattcc agccaagaaa
     3841 attgaattta gataatgctg aatcatttga aaaccacgga ttggattatt tcgtgaatga
     3901 tttgatgaag tatgctggaa aaaaagtcgc tattgctgga ggtggtgatt ctgctatcga
     3961 ttggacgttg atgttagagc ctattgcaag cgaagtttac ttgattcatc gtcgcccgga
     4021 atttcgtgcg cacgaacata gtgtatcacg cttgaaatct tcatctgtca acttgcttac
     4081 tccctatctc atcgatggat tatcaggcaa taatggggaa ctgacagata tccggttaaa
     4141 aaaagtgaaa agtgacgaga cgattgattt gatgattgat tctctgatcg tcaattatgg
     4201 attctcttct aatttagaac atctttcttc ttggggactt gatagtacca gaaatgccat
     4261 tactgtaaaa tcagatatgt ctacttctat tccaggcgtt tatgcagctg gtgacatctg
     4321 tacctatgaa ggaaaagtga aactgattgc tactgggctc ggtgaagcac ctactgcagt
     4381 gaacaacgct ttacactata ttaatccaaa ggaacgaact cagcctggtc acagcacaag
     4441 cttatacgat aaaaatcttc gtcctagttg attttttata tctctttgca tttcaagtta
     4501 aacccgaaag cagtttcttg catttttttc atgttccgtt aacatgaaat agagaaagaa
     4561 aaaataaagg gggagcaata atatggtcgt caaaactgag actttagaag aaaaggcaag
     4621 agaactattg aaggaacgtg gcgtaactgt agaagatatc gcacaacttg tcatgttttt
     4681 acaaaaagac tatatttctg atttgacttt ggcggattgt actgaaagtg tcaacagcgt
     4741 gctaacaaag cgtgaagtac ataacgccat tatcactgga atccaattag atatattagc
     4801 agaaaagaaa aaattgatga gtccgttgca acatattatc gaagatgacg aaggccttta
     4861 cggtatcgat gagatcctag ccttgtcaat cgtgaatgtt tacggtacga tcggctttac
     4921 gaattatggt tatatcgaca aggtgaaacc tggtatttta aaagaactaa acagccacga
     4981 tggcgttcat gtccatacct tcttagatga tatcgtcgga gcgatcgccg ctgctgctgc
     5041 cagtcgatta gcacacaaag aaccagaaaa aagaagtcgc cttactcaat aattcaacaa
     5101 aaaaagaaag aaaacgtcta tttagacgag ttctttcttt tttgtttgtt tcaagctatt
     5161 ttttcctaag aaaagaaaaa cagcaaaaaa taattctaat aatacaaaaa ataagataaa
     5221 gctatgcatg aaaaattctt ctggaagtac attgatgatt ggatcagtaa cgggatcgaa
     5281 taaccagtca tcgttgttga aaaacgtttc atgaaaaagg ataaaaaagc gatcaaatcc
     5341 tatcatcatg aaaaaaccga aaacaactgg cagtaacatg ccgatttgaa acggacgaat
     5401 caaccgccaa agccgatcat tcttttgcaa atatttgata aacaaaatac tcgggatcaa
     5461 agtgatgaaa aacacagcat aatccactaa aaacaaaatt ttcacttcat aaaagtgatg
     5521 ggctccgcta gcagaaactg ggaaatctgg caagctgagg atggttttga agggattatt
     5581 gagataattc attaggtgat caaaattttt cagtaacgtc tcttgatcta aagaagtata
     5641 atccaaaatt tgcaaatgtc cgatatcaaa tacgtatagt ggtcgaaagt tgatcgtcac
     5701 accaactgcc agactgatca gtgtcagaaa taggctgaac aatccagcat attccatcca
     5761 ctgccatctc gaatttttca tattagaagc tccattcatc cagtgattgt ttcacatagg
     5821 tagctgggat aggcaaccca ggtacatctt cttcttttgt aaaacctgat aaaacgagca
     5881 aagtatctat attattgcgt atcccagctt ggatatctgt ttcatagtta tctccaacca
     5941 tgattacttc ttctttttgc agccctaata cttcaacggc tttatccata atgatggctt
     6001 ctggttttcc gatgtagatc ggcggcgttt gggttgctgt ctctacaaaa gagatgactg
     6061 accctgctcc aggaagaagg ccgcgttcag taggtatatt cttatctggg ttcgttccaa
     6121 tgaaagtagc acctttttga atagcaagtg ttgctttaac tactttttca taggtcagat
     6181 aattatctaa gcctaccact acatagtcag gagcctcttc ttcccatgta aatccggcag
     6241 ctaaaatcaa gtcaatcaat cctgcttctc cgataacata gacttttttc ccttttccat
     6301 ctgctttcat aaaatcgatt gttgccaaag tagctgtgta gactgtctct ggagctacat
     6361 gaatgtcaaa ctcatctgct agacgattag ctactgtttc tggtgactta gtcgtgttat
     6421 tggtaacaaa caagaaaggt aattttcttt tttgcaattc ttccacaaat cgtttaccgg
     6481 ccggtatggg ttgtgtccca cgataaatcg ttccgtctaa atcaattaaa tatcctttat
     6541 agtccattca tccactactc ttcccttttt ctgatcgtaa atgctgtttt tgttttttct
     6601 acttgtttag gttgttcttg tttttttact ttttcagagg tttttgctga ctctgttttt
     6661 cgatttttaa taaccggttt tttgcgatta gatgcgactg gtcctttttt ctcatcgata
     6721 tacgcacgat tatggttttt tttctttttt cggcgctgag ttgtcttttc ttttttaccg
     6781 ccgattctct cgatgacaaa atacgcacaa ccaaaattgc aatattcgta aagatagtct
     6841 tccaaggaat cgattcgctg atctggatgc gcccgtcgat tatccgcttg gaaaaatcct
     6901 tttaggcgta gttgttcata accccaatct cctacgatat aatcatatcg ggctagtaca
     6961 tcactgtaac gttctccaag cttttctgca ttaaatcctt cacgataatc ggacacaagc
     7021 cgataatgtc tttcacctat caaaaaatta ctgtcatcta acagtgtcac tagctcgcct
     7081 ttgacttttt ctgctttagg ctcctcaacg atttcttcca aagcagctgt cagttcttcg
     7141 gtgactgttg tttcctgttc agctgatgat tttttcttag caatttctgt tttatgctca
     7201 acgttctgct gttcattttg ttttgcagac atgcgttcac cacctatctt ttttattata
     7261 ccttgttttt atttgattgg gtagtgagct ttcaagtaat ctcctaccac acttcggata
     7321 aattcaggga acaaaaattc attttttcca gcaatctcaa tcgttggaaa aaatggaaca
     7381 aacatcaaat gatctacggt agtaaaagta taatttttat tcagatcgat tggcttgttc
     7441 ttccaaaaga cttgatggtt aatagaatca tatgtgattc cattatagac catctgccca
     7501 aaaatcttac cgcgaaatcc cattcccttc ataggatagt tacgtaaaaa gttacgattt
     7561 ttttctattt ctaaaactaa gcggatcaga tcatttccac ccaatgtgac atttaacaag
     7621 tgcatcggat gcggcaacgc agtgtgaagc tgatcctgat tgacccgccc ttttggaatt
     7681 tcagttaaaa acagaccact gtttaatatt gctgcttccg tctttcctcg ttctttcacc
     7741 gcctcaaagg ctacttggat aaacgaatgc tcattgaaga tatctagact cagagaaaat
     7801 ggcaaatctg ctacttcttt ttcttttaat aattcatgcc cacgttctag ataactattt
     7861 atttcttgtt catcttctgt aaaagctgtc attgtttcgg tagggatggc tttggctgaa
     7921 tgcttaagga tttttttctc ttcatcgatg gttaaatgga cttcaccgac atactgcccg
     7981 tactttccag cggctgctat ttggacatca ttgattacgt gaccttctct gaataaatga
     8041 tgggtgtgcg atcctaaaat aacatcaatt gctggtattt cttttgcaat ttggaaatca
     8101 tcctgaatcc cgagatgact catcaaaact aaaacatcca cttgtgaacg taaatcttcg
     8161 actaattctg gcaaaatatc ataaggattc cgtatgtccc agccattcgg attataagta
     8221 agcggaaatg gagcagtaaa tgcaattagt ccgattttcg tctggtgttt cgttgtaatg
     8281 attttatatg gtttcgtcca tgccggtggc tggagcgtat ttttatcgaa taagttatcc
     8341 aggatgatat caaactcagc atgatcgtat aaatgattca actcttcttt ggaatttcct
     8401 acgccttcat tgtttcctat cgtcgctgca tcataaccaa cttcattcat cagcaagata
     8461 ttttcctgtc cattcgttgc ttctgacaat ggatgccaac gatccacaaa atcacctaga
     8521 tctactgcaa tcgttgtcgt tttttctttc ttttcgtttt ctcgtttacg ttgatccaaa
     8581 aaccttctga tccttggcca attttctaaa tgagaatgca gatcattcgt atgtaaaatc
     8641 actatttttt ccatgtaccc tctcgcctct ctttatcttt atcataccat aggcagcttt
     8701 ttcttccatt gaaacaagct ctatttcaga gtttttcctg ccttgaagca aattgtataa
     8761 gtacaatatt cgataaatca gtctggctaa aaaatcagga acattcattt ttacagtact
     8821 ataaaaataa aaaaaacaga cccgaaagtc tgttgtcgtt tcattataat cagacacatg
     8881 gcggaacctg cttagtgctg cttccttcca gacctgacac gcttcacaag cccaccattg
     8941 tcctagcctt tcggcaaaga atagtatacc ttatttttca ttcgttgacc agtctttttt
     9001 taatttcttt tttcgctggc ggagctttcg gaaaaagtca gtcaaaatca tcccacattc
     9061 gtcttctaaa atgccacctt ctacatatgc ttggtggtta aaccgctcgt cctccaaaag
     9121 attcatcaag gtaccggctg ttccgccttt tggatcatac gcgccgaaat aaacttctgc
     9181 tacacgagac aaaatcatcg cgccgctgca cataggacaa ggctctaagg taacaaaaag
     9241 tgcagcatct tccaagcgcc agcttcccac tttttcacag gcttccttga ttgcaagcat
     9301 ttctgcatgt gtagtagcat cttgcgtggt ttctctaagg ttatatcctc ttccaatcac
     9361 ttttccatcc aatacaacca ctgctccaat cggaacttca tgaagcattt ctgctttctt
     9421 tgcttctgcc aatgcaaggc gcatccattt ttctttttct actgcatcaa gatttgtatt
     9481 taccaattac ccttccctgc ctttgttttt tcttgtttta ctttagcata tgataaaaag
     9541 gctgtaacta actttttttt ctatggtaaa ataaatacaa gaggtgaaca agatgaaaat
     9601 ggataaatta cttgctcttt acccacaagc acagaaaaaa aactctccag catcagaagc
     9661 ggatatcctt tcttttgcaa ttgatgatgc ttttatctgg atcaaacaag attcattatc
     9721 tcaacaagaa accagccttt tgaaagcgtt attccctgta atcaacgatc aaaaaaaaca
     9781 cccatggtat cactatcttt ttaaagatgc ttcttgtgtt caagaaaaaa gctttcgttt
     9841 gatccagctt cacgtcgaat caaaaggaga attcttaaaa aaagaatggc aagatactat
     9901 tttggaatta tttcgctatt ctgctgattt ctttttttat acagacacag atgcgctctt
     9961 agtcgaacaa ataaaccgtg attatcttga tgctactgaa atcaacggta tttttctatc
    10021 tttagatgct gattttgata cgacaacgtc tgtattcgtt ggttctttcc attcacctgg
    10081 caccgacctc gtccctttgt ttgctgaaga aagaaaaatt tttttaacag agcaaaacaa
    10141 tctttatact cacagccgta ctttttctat gcaagatgtg gctttacatt actatacaaa
    10201 agatactgta aaagatagta agttgatcaa aagttacata gaactgatca aacaaaatga
    10261 aatggaagtg atcattcaag aattatggaa tgaattaggc aatgtcagct ctgctgcaaa
    10321 aacactgttt cttcatcgta atactctaaa atatcgaatc gaaaaatttc aagaacagtc
    10381 tggtttcaat ctaaaaaaag ccaacgattt actgttttgc tatcttttat tgcttcatga
    10441 acataattaa agatagatta aaggggttgt gacaataatt ttgtcacaac cccttatttc
    10501 gaatgaatag tgttcaaaag ctagtttctc ttacatcatt ttttcaacaa aatgcattag
    10561 ccggtctttt acatcttcgg ttgaatcttt gattgaatca ccataaacag agattttctt
    10621 ttttcctgat ttgatttttg ctaacattcc catcaaagaa tccaagtcac tatctgaaag
    10681 accatctacg atttctagta atttttcatt tccatcaaat ttgtcataga cgaatttttt
    10741 tactttcgtc cgagtagtca tatgatggat cttttccatt acttttcccg atacaacgac
    10801 tgctgtcgct acactggcag cggctgctac gcttaatccg attgttactt ttgttgatgt
    10861 tttcataagt atcagctcct ttttatctat ctccatcata gcatagacaa aaaaataaac
    10921 gaactaatcc actcagtgaa atctcaatcc tttagggaaa aagttcttta ctgttccttt
    10981 tacttgtttc ccaaatccga caggtatctt atctaatact agcaaaaccc atccttgatt
    11041 cccatcacgt tgaaatgttt ctcctgctgt gtaagattgc cattcctttt gagtgatcgg
    11101 caagcaaggt atattctcta tcttttttgt agcaagcgct aatgcatagc taggttcaaa
    11161 tcgattcttt ttgaaatctc ctaaatgcaa acctgtacgt acgactttta aaccatcgag
    11221 agaaggggct aactcaggaa cttcccaaag atggtcgttg aacactaaaa gtcttccagt
    11281 agcttcataa tgaaaatcat ttgaaaactc cgtccagagt ttttcctgct cttttgtcat
    11341 ttgcacttta cttttttttc gtgtcttctt ttctttatgc atctgatttt gtccatgaaa
    11401 agtcagcttt gcaacaaaat gtccttcacc ctgatcttta tgaggccata tacgtattgt
    11461 tttttccaaa ccagctacgc ttccccattc agaacgtcct gaactaacgg attgagtcaa
    11521 aggaatctcc tcaatcgtta ctggataatt ttctacaagc cagctaatga tctcttcatt
    11581 ttcttctggt gcaaacgtac aagtcgaata aatcagttgt cctttatttt ttagcatttt
    11641 tattgctgaa gacaaaatct cttgctgacg tttttgacag tatagcggag attcttctgt
    11701 ccactctttt attgcatttg gatcttttcg gaacattcct tctcctgaac aaggagcatc
    11761 aaccacgatc cgatcaaaaa agcccgaaaa atgagggaca agttctgcgg gtgcatgatt
    11821 tgtcactatt gcgttcgaaa ctccccatcg ttctatattt tctgataaaa tcttcgcacg
    11881 tttcggaaag atctcattcg tcactaataa ccctttcccc ttcatttgag cagctaattg
    11941 ggttgattta ccaccgggag ccgcacacaa atccaaaact ttttcaccgg gttttgctgc
    12001 agcagctgtt ccaacgatca ttgcacttgg ttcttggcta tattcatacc cagcttgatg
    12061 gaggaaagac tttccattga cagtgccaag aaatccctca ttgctgtagg gagcgggttg
    12121 taattcttcg ctatggtaag tttggaccat gtccaatcct gccggtttta gtggattcca
    12181 ccgaaatcct tttttcacgc ttccttgttc aagcgcagaa aaaaaatcgg atgcttcttc
    12241 gcctaaaaga agacgatatt ttttgataaa ttgctgtggt aacgttgtcg cttcctcctt
    12301 cattccaatg tttcgttaga cattttacaa tcttttttac gaaaaataaa ggtggctgat
    12361 ctactttttc atgttgctgc ctaaggtgac tgttccttta agatattttc caagtattca
    12421 tccgtcacct cgtttttatc ccaaacagcg ttcatcattt caagaaaatc ttgagaagaa
    12481 tcatctgagc gcaaacttcc caatgcatta agccatacca attcaagcga cttttcttct
    12541 ttgatcttcg tgtgaccttt gacatatgag aaaaatggcc gcttaaatag cgaatccatg
    12601 tctaaatcag attttgcaat gatttcacga atactttcat ggatagaaaa aaaatctttc
    12661 aataagtaga caatgcttaa aacatcatcg gaactgcatt cagctaagta gttttcaaaa
    12721 taaacagtga tttcttctaa tatcttctct tttaacccgc tgattgattt gaaatgtgta
    12781 taaatcgggt atgtagaaca accgcagaac tctgctaact ctcttgcagt aattgacttc
    12841 attccatatt cttccacgta taccatactt ttgaacagca aatattcttt actataattt
    12901 gttactctcc ccatcattct tacctccgtc tcttttcatc tacccataaa taaataacat
    12961 aaataattct aaaaatatta tt
//
LOCUS       DADQDV010000077        12740 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.080, whole genome shotgun sequence.
ACCESSION   DADQDV010000077 DADQDV010000000
VERSION     DADQDV010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12740)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12740)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12740
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.080"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            99..542
                     /locus_tag="J8S10_002433"
     CDS             99..542
                     /locus_tag="J8S10_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAZ9631001.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(548..1732)
                     /locus_tag="J8S10_002434"
     CDS             complement(548..1732)
                     /locus_tag="J8S10_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HAZ9631002.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            2000..2698
                     /locus_tag="J8S10_002435"
     CDS             2000..2698
                     /locus_tag="J8S10_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HAZ9631003.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            2705..3382
                     /gene="nth"
                     /locus_tag="J8S10_002436"
     CDS             2705..3382
                     /gene="nth"
                     /locus_tag="J8S10_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HAZ9631004.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(3508..4041)
                     /locus_tag="J8S10_002437"
     CDS             complement(3508..4041)
                     /locus_tag="J8S10_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631005.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(4338..6719)
                     /locus_tag="J8S10_002438"
     CDS             complement(4338..6719)
                     /locus_tag="J8S10_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HAZ9631006.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(6709..7356)
                     /gene="recU"
                     /locus_tag="J8S10_002439"
     CDS             complement(6709..7356)
                     /gene="recU"
                     /locus_tag="J8S10_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HAZ9631007.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            7420..7959
                     /locus_tag="J8S10_002440"
     CDS             7420..7959
                     /locus_tag="J8S10_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HAZ9631008.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            8049..8468
                     /gene="gpsB"
                     /locus_tag="J8S10_002441"
     CDS             8049..8468
                     /gene="gpsB"
                     /locus_tag="J8S10_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HAZ9631009.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            8490..8857
                     /gene="rnpB"
                     /locus_tag="J8S10_002442"
     ncRNA           8490..8857
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="J8S10_002442"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            9066..10232
                     /locus_tag="J8S10_002443"
     CDS             9066..10232
                     /locus_tag="J8S10_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HAZ9631010.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            10278..11774
                     /locus_tag="J8S10_002444"
     CDS             10278..11774
                     /locus_tag="J8S10_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HAZ9631011.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            11855..12538
                     /locus_tag="J8S10_002445"
     CDS             11855..12538
                     /locus_tag="J8S10_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAZ9631012.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
BASE COUNT         4273 a         2230 c         2630 g         3607 t
ORIGIN      
        1 tttcttggtt tcagattggg ttttcctaca aaatattttt atctttgttg aataggaaac
       61 aaaaaaacaa tataatgaaa gaaaaagaag gtgtagaaat ggataaaaga caactgctaa
      121 tagaagaata tctggattta gctaatgaga ttattcatcg taataaacca gaaatggaaa
      181 aagaatttgc aggatttact ctaaatgaac tagaagtgat tgaacatatc gggaaaatcc
      241 ctgatcctaa cgtgacaaaa ttagcgaatg ctagttacat gactagagga gccatcagta
      301 agctaacaaa aaaactgata gctagaggga tcataaacac ttatcaaagc gaagagaata
      361 aaaaagaaat ctattttcaa ttgacgccaa tcggacaaaa aataaggaat agacacgagc
      421 aactccatca aaaatgggta cagcgagatg ctactgtatt tgaaaatatg tcaaaagaag
      481 aatttgacac agtatttcgt tttatcggtc gatacagaga atttatacga agtagcaaat
      541 gaagctacta ttttttattg tagtgataat aggcaaaaat cataagcaaa aatccgaata
      601 ccgtcggaag aaatggtgct gcagcataaa gctgtcctgc gattagcggg ccgatgacgc
      661 gcgatagaga ttgtatactt tgggtaccgc ccattacaag accttgctgg ttatctgaga
      721 cagaattgga tagttggcca ttgaatacag gagtaaaaat agaatcaccg aaaccataac
      781 agataatccc aaataaaaac aaaatcggca gtagaagaat tccagataat gtgatgaata
      841 gataggcgag gatttcactg aacatcccta ttcttgtgat ctgctgttct gaaaattttt
      901 tgagcaatcg aggcataatg aacaattgcg agacagtatc caagattcca atcaaagaga
      961 agcttaaacc aaccaaccca gccttccact gaaaggcgtc aatcgaaaat tgagaaaaga
     1021 tagattgaag agagccagct gccaaccaaa cagcaaaacc tgctgtcaat aaaggaataa
     1081 cggatgaaat cttgaataat tgttgtaatt ggtgaaaagg tcttacatgg gagaaactta
     1141 aatctactga acgttttttt attggaaggc tttctagcat aaatgtgtag ccataaacgg
     1201 catttaagaa agtaaagagt gctccaataa atataggaac agaattcccc aactcagcta
     1261 atagaccccc tataatagga cccagcgttg ttcctatacc gactaaagca cccatccatc
     1321 caaaaacttt ggttctttca ttaggttccg tgatgtcggc aaagtaagca tataaggtgg
     1381 agatttctcc tgccgtcaat ccttcaatga tacgaccaag gaacaacatc catatcgaat
     1441 ttcctaaacc aaaaagcaaa tatccgatac ttgatcctaa taaactgata ataaggatcg
     1501 gatgacgccc aaaatgatca cttaagctac cgagaatggg ggcagataag aaggcagcta
     1561 gagcataaac agacatgagc aaagtgatat agaaagcttg ctgatgtatg gagtgagaat
     1621 aaggcagcgt taaaaacgga agtacaggac tgacgatagt aaatcctaat ccagtgaata
     1681 agacagagac gtatccaaaa actttagaat gtttatttgt gaaactgtac atgtaaaaac
     1741 tcctttatgc aataatgtta acttggaaac aaaaatagtg tatagtaatt ttgtttcctt
     1801 gtcaacattc taaggaacag cgaaatctac ttaatttatt tattccgaaa agtgaagata
     1861 cgcatcaaaa acatgaacaa acaaaaatca agtagacgac attgtaaatc tgaccgatca
     1921 gtgaagtaaa tagaaaagaa acctgttctt gcttcccatg ttttttttac gtatactgtg
     1981 attgagcgga ggagaaatca tgttgaattt agaaaattac ttaagcgctg gacaaacagt
     2041 catatctaat cttttactta aaaattatca taggatcggt ctacaatctg aagaattttt
     2101 atttgttcta cagttgcata tggcacagct tgaaggagat actttccctg atttgcagat
     2161 gattgctatg gatatgggaa tcaaacaaga tcagattttt caaatactgg atcgtctcgt
     2221 aacaaatgga tttatcaaga tagaaacgac gattgtcaac ggtaaaaaag cagatcgata
     2281 taatctttac cccatctatg atctattagg tgagtattta aaaacacaag aaaaaaaata
     2341 cgaagaaaaa acacaagaaa aagaaatcca gtcagtgtat caattatttg aacaagaatt
     2401 tggacgcccg ctttcttcga tcgagttcca gcggatcgga caatggctag aagaagacca
     2461 ttatcagccg gaaattttga agctagcact gcgggaagcc gtattaaatc aggcttatag
     2521 ttttaattac gttgaccgca ttttgctatc gtgggaaaga aaaaatctac gtacaaaaca
     2581 acaagtggaa gaagaccaaa aacgaagaaa acagcagctt cttcaaagag aagtagaaca
     2641 gtcagctcaa caagaagaat tgccgaaagt ctcactgaaa aattggttgg aggagtagcg
     2701 gaatatgtta agcaaacaaa aaacaatgga agctctagaa acgatgtatg gaatgtttcc
     2761 cgaagcacat ggagaactca agcacaataa tccatttgag ttattgattg cagtgatctt
     2821 aagtgcccag gcgacagatg tatcagtgaa taaagcaacg ccagatttgt ttgcctcttt
     2881 tccgacaccc gatgcgttag cagaagcttc aatcgatgaa atcattctta aaataaaaac
     2941 gattggtttg tatcgaaata aagcaaaaaa catcaaagcg tgtgcacagc agctgattga
     3001 acgtttcgat gggcaagtgc caacgtcaag agaagaattg atgtctcttc ctggtgtagg
     3061 cagaaagaca gcaaatgtcg tattggggga tgcattcggg ataccagcaa tcgcagtaga
     3121 tacccacgtg gaacgtgtct caaaacgcct gaggatctgc aaactagatg ctacggtcat
     3181 ggaagtagaa gaaacactga tgcggaaagt accacaagaa ttatgggtaa agacacatca
     3241 tacactgatt ttttttggta gatatcattg cacggcaaga aatcccaagt gcgaggtatg
     3301 tcctttgcta tcaatatgtc aagatgggaa aaatcggatg cgtctaaaag aaaaggcgct
     3361 aaaaaagaaa ccacgcctgt agacgtggtt tctttaattg caaataaatg tatgaattat
     3421 cttgttatta tggagaaaag ctgtttcgtt tatctttttt gcatgaaaaa gtaaatgtac
     3481 atactcagta gctaggatgg taacttatta caatttattg cgataaaaat aaaagttgtt
     3541 atttttattg ggaaaatacc cgatgtagaa aataatgcct tccaatatac ctataaaata
     3601 agtccagtat tccaaaggat tatataaata agtgacgtat ctatctaaag gtgtaataaa
     3661 aatgataagt gataataaaa aaataccatt tataactaaa cataaactaa tggatttggg
     3721 cggtttcagg ctcatcagaa aaatatagat tctggtgaac aacaaccata aaaaagtgag
     3781 aatcattgca tgagagcttc tttccataaa ttttccttta agagtagtgc ttaaaagtac
     3841 agaaaaaata ataaatgcaa ggataggagc aattaaagta aatttattta ataataaaca
     3901 aaatttttca gcttttttat tcttggaata acgaggtatt gttttcgata aaaaaagatg
     3961 gtgcagacaa attatgataa ttaagcatac tatcagataa ctcaaaatga agccttcttt
     4021 caaaaaatta ttcaaaacca tatattgtat tttttatttg ataataacaa tgggattatt
     4081 aagaagtggc actaaataaa agactagtgt gtatttagcc gatttaatta taaacaagta
     4141 aatggataaa gtatatgtaa tgataaaaga aaaatggatt ttctaatttt taagctaaat
     4201 gttagatcac acatgtatat gctggatagt cttataaaaa atcatgtaat acagcttggt
     4261 acatgatttt tatttgtagc tgttttttac atagacacaa aaaagaaacc acgcttgtag
     4321 acgtggtttc ttttttacta tctgtttcca gaagctgagg tgctgctgga tggtgtatgg
     4381 tcatttgcag catccgctcc gctagttgct ggctcactgg aagaagcagg aggagcagat
     4441 gaagacggtg tcgagctttc ttcggatgaa gaagaaggaa ccgttgttga agacgctggc
     4501 tcgcttgttt ctgctgtcgt gctttctttt gaggactcag cagttgattc gctttgacta
     4561 gtagagctag agctttgagt cgttgtctct gttgttgagc ttccaggagt ctggacatag
     4621 ctggaagatg gaatagttgt tgatggtgta attgcattcg atctagctgt atattgatct
     4681 ttgtagtaca gttcaccgcc cacacgaatt aatccgcttg gcatctccca gtctgtattt
     4741 gtcacgttag ctgaaacata ctgcataagc tcgcgataaa catcagaggc tacgtgtgac
     4801 gattctgaag tgacaggcgt cattttttta ttgtaacctg tccacacgga aatcgaataa
     4861 tttggcgtat agcccgcaaa taggatatct ggatacaccc cagaagaaat accaagtttt
     4921 gcatactcgt catctgtgta attggatgtt ccggtcttac cggcttgata taacccagcg
     4981 atttgcgcat tcgtaccagt tccttcagtg atcgtatctt ttaaaatgtc tgtgatcata
     5041 taagctgttt ctggagacat ggctgttttt ccatctggct cataagtttc ttctgttccg
     5101 tcttggaaga cgattttatt aacatattga ggtttgtaat aagtccctcc attggcgaaa
     5161 gccgcatagg ctgctgccat ttttaaggaa gaagctccgt attttgtccc atcttgttct
     5221 tccgtattac tagagatcgc attcgattga tggatcgtac tgtattcgat cccaagattt
     5281 tttaagaaag aagccacttt atctgaaccg acttcattga ataatttgac tgctggaaca
     5341 ttacgggata agtaaagtgc ttggcgtaaa gtaatggtgc ccatatattg attatcccag
     5401 tttcctacag gagtcgaagt cccttcatag ttatacggtg cgtcagtaat agtttttcca
     5461 gtagaatatt tcaaatattc aaaagctggt ccgtaatctg tgacaggttt catcgtagaa
     5521 ccaaaatcac gggaagtatt cactgctaag ttgttgccta aagttacgtc ttctgcgatg
     5581 tgacgtccgc caatctgggc ttttactttc ccggtattgg tgtcgataag ggtggaggca
     5641 acttgcatct cgtcgtctgg gtaagagaca tactgatccg tgttgacgat atcatatagt
     5701 ttcttttggg cgtccagatc caaattcgta taaatctcta aaccgtctgt gtagacattc
     5761 ttatctgttt tttcttgtac ttcattgatg acttctttga cataattatc gacgatctta
     5821 gtattgtcat cggattgagt tagttcttgc agaccatccg ttaccggtac attaacagct
     5881 tgatcatatt ctgtttgaga gattttttcg ttttgaagca tcgtatacaa aacagtatct
     5941 cgtcttttct tcgcctgatc tggataaaca taaggatcat aggcggaagg ggcttgaggc
     6001 atcccagcaa gcaatgctgt ttgcggtaaa gaaagttctg ataatttctt accaaagtac
     6061 atctcagaag ctgtctccat cccgtacaag ccgtttgaca tatacacttt atttacgtag
     6121 taggtcaaga tctcttgttt cgattttttt tgttccaatc ttacagccat ccacgcttct
     6181 tgggccttgc gtttcagagt ctgatcctcg gcactggtgg agaagaagga aagtttgatc
     6241 aattgctgtg tcaaagtact tccgccttgc agtccgccag aggtaaagtt agagagggca
     6301 gaaccgatga tccgaatagg gtcaaccccg atgtgtttat aaaaacggcg atcttctacc
     6361 gacacgatcg catcttctaa tgttttcggt aattcattcg cagaaatttt ttcacgcttt
     6421 tctgcgccta aatcttcgaa tagttcgcca tcttgtgtat atagtttgga agatacggta
     6481 gcgtctaatt ttttatccgt caattcgggc gcatcttttg cgtaatacca gaaaagtcct
     6541 acacctgcta aaaagaggat acagaaaaat gagagtattc ctaaaaggat cttgataaat
     6601 aatccttttt tatgtgttcc agaggacttt ccagaacctt tgccagaatt cttcttcaca
     6661 ctctttttag gagtaggctg tttctgtcgt ctagagcttc tagtttgttc atttgccatt
     6721 cttgctttct ccttcaatag ataatgttga taaatagaag tcaaccgcgt ccaaataagg
     6781 aatccgcgga gaaataccag ttttgatctc tattcctagt tcttcgatca aagataaagg
     6841 tagtgatttg cgtccttttt ccttttgggc gtcccagtaa gcaatcaaat gaacactatt
     6901 caaataaaaa cagcgcttca aagacgaaaa ccataacaag acaaagcaga ccccattttg
     6961 ttcgaggcat gctttcatat gttcgatttg atgggcatgg aagtttttaa agggaaaaga
     7021 tgttttgttc ttggtttctt ttgcttcaaa gtccaagtaa aagcctcgat agacgccatt
     7081 atagtctgta gttgaggctt gggtaaagta ggcttccttg atcacagcag cacttctctt
     7141 aggatagtct actttcacga tttggatagg ggtaggcttt ttatggataa ccgccaaccc
     7201 gcgggaaaga taatatttat tactttcatt gattgcttct tcaaagcgca tcccccgatt
     7261 gccgaattca gtgatctgat ttcttttttc ttgaattttt tcgacgggag aggcattctt
     7321 ataataaggt tggccatttg gatagcgcaa taccatcttt aatcacactc ctaggccaca
     7381 ttatagcaaa aaagcggata gaaagaaaag gaatctgaga tggataagtc aaaagtaatc
     7441 tatgtgtctg ggtatcgaag tttcgaactc ggtgttttta aagaaaatga tcctaaaatc
     7501 caagttgtta aaaatgtttt aaaaaaagaa ctccatcagt tagcagaaga agggctggaa
     7561 tgggtacttg tcagtgggaa tttgggcgtc gaactatggg ctgtgcaaat agtagcggaa
     7621 ttgaaagaag aatatccgga actatctctt ggtattttgt atcctttttc tgattttggt
     7681 aataactgga atgaagggaa ccaagaaaaa aaacaattag cagaacaatt agcagattat
     7741 gtcgaagctg ttagccatca accctaccaa tcacctagtc agctaaagaa tcacactcgt
     7801 tttatacttg agcatacagt gggctgtctg ctgatctatg atgaagaatt ccctggaaaa
     7861 acgaagtatt tttttgaaga tgcacagaat taccaagcag atcatcccta cgaaattcgg
     7921 ctgatcagta tggacgatct tcaaaatttt agtgaataat cgatattgtg tttgatttat
     7981 caactttttt cctatacaat gaaaaaggta gaaatgttat tacgtaaatg aaaactagag
     8041 gtgtaaatat ggcgaatttg gtttatagtc ctaaagacat tttacaacaa gaattcaaaa
     8101 caaaaatgcg cggctatgat cccgttgaag ttgatgaatt cttagacaat atcatcaaag
     8161 attatgaaac ttacagcaaa gaactccttg ctttacaaga agaaaacgat cgattgagtg
     8221 caaaagtagc tcaattatct aaaactcaag gagcagctca aacacgcgtg caacaaacag
     8281 aggcaccaaa gagcgcagca gtgaccaatt ttgatatctt aaaacgcttg tcaaatcttg
     8341 aacgtgaagt atttggtaaa aagcttgatc aacaagcaag tgcagtcaaa ccagcacaac
     8401 ctaatccaaa taactacaca aatgcagaca caagcttaga tgataatgaa aaaacacgtc
     8461 aattttaatt tttgattaat gaatttgcgg ttttcgggta atcgcggtct gacttgatca
     8521 ggctgaggaa agtccatgct cgcacaggct gtgatgcctg tagtgttcgt gcttagcgaa
     8581 accataagct aaggtactct ttggagtaac ggcaggaaaa caagctaagg cttcggctat
     8641 gcttaagtat ccttgaaagt gccacagtga cgaagcggct ggggaaaccc atccggtgga
     8701 acgcggtaaa cccctcgagc gagcaaccca aacaatggta ggggcgcttt ttgtctggaa
     8761 gaagaacagg acaaaaaggc agtataactg cagatagatg gttaccgctt tgttttttct
     8821 ccctggaaaa gcaaagtaca gaacatggct tatagaaaac cgcaaacatc agggaattag
     8881 gtcgtgacaa aagtaatgcg ttataagaaa caagaaaaac atttgaaagc tatttttcaa
     8941 tacttcagat gaatcgttct tattacaaaa caaacttttg tatcaccggt tattcggaat
     9001 ttgagtaaaa gtgtggggta ggactgatgt cccacctcct ttttttataa ataaggagat
     9061 tgtgtatgga aaaaaacagg aagttcaacc tcgtcgcaac tgcggcaagc gggctagaag
     9121 cactggttgg taaagaatta agagatcttg gaatcgaatg ccaagttgag aacggacgtg
     9181 cacgttttga aggaacaatg gaaacgatcg ctacagctaa tttatggtta cgtacagcag
     9241 atcgagtaaa aatcgtggtt ggggaattcg atgcgtatac gtttgatgaa ttgtttgaaa
     9301 acgtaaaagc attgccttgg gaagattttc ttccactaga tgcagctttt cctgtagctg
     9361 gaaaatcgat caagtcgaaa ctatatagca cacctgattg ccaagcgatc acaaaaaaag
     9421 caatcgttga acgtctccgt acctattatc accgtccagc ttctgtacca ctgacggaaa
     9481 ctggcgcaca ttttcagttg gaagtagctt tgctgaaaga ccatgtgatg gtaactctgg
     9541 atacgacagg accaagttta ttcaaacgtg gttatcgctt agaaaaaggt ggagcaccat
     9601 tgaaagaaaa catggcagca gcacttatta tgttgacaaa ttggcgaaaa gaccgtccat
     9661 tttatgatcc tgtatgtggt tcaggtacgc tttgtattga agcagcctta ataggccata
     9721 atatcgcacc aggattcaat cgtgagtttg cttgcgaatc ttgggattgg ttcagtcaag
     9781 aaatcatgga aaatgttcga tcagcagccg aagaaaaagc agattatgat attgaattag
     9841 atattactgg ttcagatatc aatggacgga tgattgaaat tgccaaagcc aatgcagaag
     9901 aaatcggatt aggctcttcg attaccttta agcaacaagc agtcaaagac ttcaaaacgg
     9961 ataaagaata cggggtcatc gtggctaatc cgccttacgg agaacgtcta ggagaagaag
    10021 aaactgttcg gaaattatat aaagaaatgg gcgatgtatt ccgtccatta aaaacatgga
    10081 gtaaatatat cttgactagc gacttagcgt ttgaggaatt ttacggacaa aaagcaacca
    10141 aaaaaagaaa attgtacaat ggtgcattgc gtacggatct attccagtat tggggaactc
    10201 gtccgcctag aaaaaaagag aaagacgaat aatcttacta attgattcat tcaattggat
    10261 gtttggagga atagggaatg aaagaaaaag agtttttaca agaagtaaaa gaaatcaatc
    10321 ttctacaaca agctttagga atcctcgatt gggatacaca aacaggtatg cctgaaaaag
    10381 ctagtgcata ccgaagtgaa gtagacagct atctttacag catttatttt tcaaaaaaaa
    10441 tcggtccaaa aatcaaagaa gccattcgct atttttctga acatccggaa gaattgtcgg
    10501 aagttggaac tgccgttttt gccaaagtaa aagaagagta tgatttggaa catcgcgtac
    10561 cggaagatct tatgagaaaa tatacagctg ccgtttcttc agcacacgga caatggcaaa
    10621 aagctagaga aacacaacaa ttttctgatt ttcaacacgc attgaatcaa aatattgaat
    10681 taacaaaaca gttgatacct tactggagaa aagatgaaaa gacgaattat gatgttttgc
    10741 tgaatcaata cgaacccggg atgactgtcg aaatccttga taaggtattt gatcagctta
    10801 aagaaggaat tctttcgatc cgccgtacgc tccaagaaaa agggactgaa cctgaaacag
    10861 actttttaaa tcggagaatg acgaaaaaac aacagaagag atttgtagtg aaagtaatcg
    10921 aacaacttgg ttatgatttt agtcgtggtc gtttagatga cactgtccac ccatttatga
    10981 ctggaattaa tccgaatgat gcacgaatca cgacacgatg gaacgaaaca gatttcaaaa
    11041 tggctgtttt tggagtgatc cacgaggctg gtcatggtat gtatgaacaa gacatcgatg
    11101 ataaatatgc gtatacaccg gtttatgaag gtacatcaat gggtatccat gaatcacaat
    11161 cgttgtttaa cgagatcatt attggaagta gtcgcagctt ctggaaaaag caatatcctt
    11221 tctttcaaga atgtgcagaa ggaacattcg atgatattcc ttttgacaaa ttttatcgtt
    11281 cattgaacca tacaaaatca agtttggttc gtatcgaggc agacagtttg acttaccctc
    11341 tccatatcat cattcgttat gaaatcgaaa aaatgatttt caatgaaggg gtagatgttg
    11401 ctgaactacc tgaaatatgg aatcaaaaat atgaagagta tctgggaata cgaccaacaa
    11461 atgatgtgga aggcatccta caagacgttc attggtcagg tgcaagcttt ggttattttc
    11521 cctcttatgc attagggtac atgtatgcgg cacaattact tcattctttg cagcaagaaa
    11581 tagatgtgga aaatgttcta gcgtcagacg attattctcc aatcaaaaac tggatgtcag
    11641 agcatatcca tcaatatggt gcatctagaa aaccaaatca attaatcatg gatgcaacac
    11701 atgaaccgct taatccgcaa tacctgatcg actatatgaa agacctgtat tttaatgtat
    11761 atcaggtaaa ataaaataca atttacaaag atagctgaaa ttcatctaat ctatagatgt
    11821 tttcagctat ttacttaaga aagaagtgga acgaatggat aaattacaag tgatcgctga
    11881 ttatagtatg gaccaattag cgcatgatca aacaggacat gggagcgatc ataccaaaag
    11941 agttgtcaag ttagctgaaa aaattttgga gacggaaccg caggcagacc gctttgtgac
    12001 gcttgcagca gcttacctac atgatacgat tgatgataaa gtcgttaaaa atgagaacga
    12061 ggcaaagcaa cagcttcgtg tattccttcg ctctttgcca atagtagagg aacagatctc
    12121 gatgattttt tccattatcg aaaatatgtc cttttctaaa aatctctctg aagcggccga
    12181 actatctctg gaaggtaaga tcgttcaaga cgctgatcgt atcgaagcat taggagcaat
    12241 cggcattttg cgtactgctt atttcggcgg tggacatggg cacccgattt ttgatcctga
    12301 actgtatccg caaacattca aggacaaaga aaattaccga aaaggcacga cagtgatcaa
    12361 tcatttttat gaaaaactgt tcttgctgtc tgataaaatg aatactgatt acggatatga
    12421 agaagccaaa cgaagagaaa ccttcatgcg tgaattctta gaagaatttt ttctggaatg
    12481 gtctattgac gatgaaaatt ttactccaga caattggatc aaaaataaca aaaaatgatg
    12541 gaggttgtga cagaagtggt cagctccaag atatttcgga tcattttccg taaaagttac
    12601 ttctggaaca ctgtttacca agaggtcgtg agcctgccgt tcagctccga gtcacaagga
    12661 acaatttcaa aaaatagctt ctcgtgtttg atgaatattg taacttgtga ttcggaattg
    12721 gcaggagaac accgtttatt
//
LOCUS       DADQDV010000078        12734 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.081, whole genome shotgun sequence.
ACCESSION   DADQDV010000078 DADQDV010000000
VERSION     DADQDV010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12734
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.081"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(86..265)
                     /gene="rpmF"
                     /locus_tag="J8S10_002446"
     CDS             complement(86..265)
                     /gene="rpmF"
                     /locus_tag="J8S10_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HAZ9631013.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(323..892)
                     /locus_tag="J8S10_002447"
     CDS             complement(323..892)
                     /locus_tag="J8S10_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HAZ9631014.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1078..1980
                     /locus_tag="J8S10_002448"
     CDS             1078..1980
                     /locus_tag="J8S10_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAZ9631015.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(2015..3799)
                     /gene="pyk"
                     /locus_tag="J8S10_002449"
     CDS             complement(2015..3799)
                     /gene="pyk"
                     /locus_tag="J8S10_002449"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HAZ9631016.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3873..4835)
                     /gene="pfkA"
                     /locus_tag="J8S10_002450"
     CDS             complement(3873..4835)
                     /gene="pfkA"
                     /locus_tag="J8S10_002450"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HAZ9631017.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(5003..8317)
                     /gene="dnaE"
                     /locus_tag="J8S10_002451"
     CDS             complement(5003..8317)
                     /gene="dnaE"
                     /locus_tag="J8S10_002451"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HAZ9631018.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            8548..8733
                     /locus_tag="J8S10_002452"
     CDS             8548..8733
                     /locus_tag="J8S10_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HAZ9631019.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8795..9991)
                     /locus_tag="J8S10_002453"
     CDS             complement(8795..9991)
                     /locus_tag="J8S10_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAZ9631020.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10161..11597)
                     /locus_tag="J8S10_002454"
     CDS             complement(10161..11597)
                     /locus_tag="J8S10_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HAZ9631021.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            11890..12699
                     /locus_tag="J8S10_002455"
     CDS             11890..12699
                     /locus_tag="J8S10_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAZ9631022.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
BASE COUNT         3802 a         2673 c         2249 g         4010 t
ORIGIN      
        1 tattttttat ttaccgacta caaaaaaata aacctcaagg ctccatggtt agccttgagg
       61 ttttacattt tctaattaaa atgtattaag cttcttttga cattacgtcc ttaccatcat
      121 agtaaccaca atttgcacat acgtgatggc tttttttcat ttcaccacag tttggacatt
      181 cgtttaaccc tttgattgtc aatttgtagt gtgtacgacg ttttgctttt ttagcttttg
      241 atgttcttct agctggtact gccattttgc tacacctcct tgtaaagtct tgtatctaaa
      301 ttagacacaa tatattccaa tcttacttgt tatcgtcgtc ttttgattta gaatcaaaaa
      361 gttcagatag ttttgcaaga cgaggatcaa ttttattctc ggcttcttcc atttttctgc
      421 gctggtattc ttcttcggaa acaacttccc aatcattgcc ttttggaagt tctgttgctg
      481 cttcctcttc ttttgtcaat acccgcattg gaatcgccaa taagatgttg tcttcaatcg
      541 actctgctaa attcaataat ggaccttcaa ttagcaaaat ctcatctgca gacatttgtt
      601 catctctact ttggaattgt tcttctgtca tgaatacttc gtctacagaa aaatccatgg
      661 gcagttcaac aggttctagt gaacgtgttg aaggaactgt caaagtcgtc tgcacagtgt
      721 aatgaacgat atagcctttc ttatcaactg agaccaaacc ttcgacttcc actggcgcaa
      781 catcaagtat taaattgtct cgcttcatga gagcggcttt caagtcgagc gtctcatgaa
      841 aagttaacgg tgtctcctgg tattttctca attccaataa agaccatttc atttttcatc
      901 actcctaagc aacaaaagca attatacagg gcaaaaagca tgttgtcaat gaaattttct
      961 tgacaccttg cagttcataa aaaaacagaa aaatctttat tagaaagcct ctgtttgcta
     1021 tcatcctcag aatcatttac aataatcatt attccattaa aggagcggat gatcttcatg
     1081 aacacgaaag atatcgaata ctatgtccaa atcgtcaaac aaaaaaattt tacgaaagtg
     1141 gctaattatt tccgtgtgag ccaacctact attacatatg cattacaacg tcttgaaaaa
     1201 gagtttgaca ccgtacttat tacaagagat cgatcgcatc acgaattaat cgtcacgcct
     1261 tctggaaagc agctgtttct ccatgcacaa accattctcc aagagatttc tactgcaaga
     1321 gctgaaatca ctcagttgca aaagaaaaag cttcgttttg gcatgcctcc tattatcggc
     1381 aatgaatact ttcctaaact gtcaagttac tttatcaagc atgaattgat gaatcaaatt
     1441 gagattaccg atggaggctc tcgggactta tacgggatga tccgacaagg gaggatcgat
     1501 ttagctgtat taggctcaac acagccaatc gtggatcaat atttagaaac agagttactt
     1561 ttggacaaac gtttcatgat cgtcgtgcca cctacacatc ctctttccaa gcaggatact
     1621 gtctctttca aagatatagc agatgaacag tttgtactat tgaacgaaca ttatgtccac
     1681 cccgcagcat tcactaagct ttctaaacaa acacatactc atccaaaagt tgtttatcaa
     1741 agcaatgact tgacgatttt aaagagtatg gtccgagaaa atgtgggtat cggttttttg
     1801 gcagagattg ctgtccatcc tgaagatcat ttagtttgcc tccctctttc agatgaagtt
     1861 cagcctcgct tcttgatttc attggcaaaa cgaacacagc agatcgtcac gcctcttcaa
     1921 gaacaagtag tccaagttat ccatgaattc gttacagcac aaaaaaacag ctcttcgtaa
     1981 aagaagagct gtttttattt tttattaagc taaattagat agctgttgtt tcgccacggt
     2041 aaacgatgcc gcgacgtgaa tcaacggtaa tcaattcacc ttctgtaatt gttgttgttg
     2101 cgcctttagc accaacgatt acaggaatat cttgtgcaat tcctacaact gcagcgtgag
     2161 aagtcaatcc gccttcttca acgataacag cagctgcttt ttcgattgca ggcatatatt
     2221 ctttgtcagt tgatggtaca actagaacca ttccgtcttt tgcttttttt acagcttctt
     2281 cagcagatga agcaataact gcatttgcaa cgacagattt ttgtccaacg ccttgagctt
     2341 ctaataattt agaaccaatc atttgaattt tcatcacgtt agttgttccg cgttcaccaa
     2401 ctggtacacc agcagtgatc aagattaaat cgccttctga tgcgaaacct aattcaacag
     2461 cttttttagc tgctagttca aacatttcat cagttgttga tggtttttca gcaactgttg
     2521 ggtaaacgcc ccagtttaac atcaaaccac gttttgtgcg ttcgtcaaaa gtaacagcca
     2581 agatatctgc atctggacga tattttgaaa tcatttttgc agtgtatcct gattcagttg
     2641 cagcaacgat tgttttcacg cctagatttt ttgcagcacg agctacagat aaaccgattg
     2701 tttcagttac atctgtttta tcgaattcgt tcaattggaa tgtacctaat tctgataatg
     2761 cattttcagc ttcttggtcg atacgtgcca ttgttgaaac agcttcaact gggtagtccc
     2821 cgtttgcaga ttcaccagat agcattgttg catctgtgcc atcaaataca gcgttagcaa
     2881 cgtcagaagc ttccgcacgt gttggacgtg ggttttcttg cattgattct aacatttgtg
     2941 tagcagtgat aactgggata ccagcagcat tacatttttt gataatgcgt ttttgaacca
     3001 ttggtactag ttcagctggg atttcaacac ccatatctcc gcgggcaatc ataacaccgt
     3061 cagaaacttt gatgatttcg tcaatgttgt cgataccttc ttgagattcg attttaggga
     3121 agatttgaac atgagtcatg tctttttctt ctaagatttc gcggatatct agaacgtctt
     3181 gtgctttacg tacaaaactt gcagcgataa agtcgatatc gttgtctaaa ccaaaacgaa
     3241 tatcgtcagc atcttttgga gtaatacctg gcaaactaat agaaacgcct ggtgcattta
     3301 cccctttacg tgatcctagc atacctgcat ttttaacttc tacgactaat tcacggtttg
     3361 cttcgtcttt ttcaatgatt tgcatatcga tcaaaccatc atcaaataaa atgtgtccgc
     3421 caacgtgaac atcgtcaaat aatcctgggt aagtaaccgc gattttttct tttgaaccta
     3481 catgttcagg atccatagag atgcgtgttt gatctcctac ttcaaatttg atgtatcctg
     3541 cacgaccaaa atcagcttct gttgtgcctt gaacagttgt acggatttca gctccttttg
     3601 tatctaaaag aataccgaca tcttttcctg tctttttaac tgcttcacgg accatagtca
     3661 tacgtgataa ttgttcttca tggtcaccat gagaaaaatt aaagcggaag acatttgccc
     3721 cagattcaat caattgagaa ataatttcta ctgagttact tgctggtcct aatgtactaa
     3781 cgattttggt ttttttcatt taaaaaactc tcccattcaa ttttgtttat ttaaagctgt
     3841 acacagctta aatagcttgg tttctttcac tcttaaaatg aaagtgaatt atttagatca
     3901 tatagtgata agtctggttt atgtttgttg ttttcaagtg tatcaatgat gtcagacgca
     3961 acgatttcgt tgtcatggat accgacacat aatccacctt ttccttcttg aagcaattcg
     4021 acagcgtaag caccgaattt acttgccaac acgcggtcgc gtgcgcttgg tgctccacca
     4081 cggacaacgt gtcccaagat agatacacgt gtatgatagt caccaaattc tgaaagtttc
     4141 tcagcgaatt catttccgcc cattacacct tcagccaaga tgatcaagca atgtttcttc
     4201 ccgcgatcgc ggccttcttg gattttttta gcaactgaag ccatatcaaa atcatgttct
     4261 gggatgatga tttcatccgc tccgccagcc acacctgacc ataaagcgat gtctcctgca
     4321 ttgcgtccca ttacttcgat aacgaatgta cgaacatgag aagtcgctgt gtcacgaata
     4381 cggtcaattg attctagtac tgtattgatt gctgtatcaa aaccgattgt gaaatcagtc
     4441 ccaggaatat cattatcgat tgttccagga atacctactg ctgggaaacc gcgttttgtc
     4501 aaagccattg cgccatgata agagccgtct cctccgataa ccactagacc ttcgattccg
     4561 aattttttca attgttcgat tccttttaat tgaccttctt cagttgcaaa ttctggataa
     4621 cgtgcagaat acaagaatgt accaccacgt tggatcttgt cacctacatc tgccacatca
     4681 agacgacgaa tatctccagc aactaaaccg gcaaaaccat aattgatccc gtatacttcc
     4741 agtccttcgt aaataccttt acgaacaacg gcacgaacag ctgcattcat tccaggtgcg
     4801 tctccgccac tggtcaaaat tccgatgcgt ttcataataa acattcacct cattaaaata
     4861 ctttatccta agtatgactt aggtttacaa ccatttttgc gttaaccacg actaacattc
     4921 taacattatt tttctcactt gtcttgattt acggataaaa aaatgaaaaa aaatgaaagc
     4981 aagtagtatt ttttaccgta agttatttga aaaccacatt atcttcgcca agcagataaa
     5041 taagttgccc ctttatactc ttgctgtcat ccacccaata agcatctgac agaactactt
     5101 ttcgttgcgt tttttcgtga tacataacta ctggtatata tcctgggtgt ttctgaaaaa
     5161 tcacttgtaa ttgtttcatt atctcgggat cttcccgttc ttctgtaata cgcaaatagc
     5221 aagtttgtga aggatactgg gcttctaact ggttaggatc agcaaagctt tctccaatta
     5281 gttgcagttc ctgattatat ttgctgattt cgctccgccc ttgaacaaag atcactcgat
     5341 caacggcaaa caaattacga tatttacgat aaagagttgg aaaaactgtg acagaaattt
     5401 ctccactact gtcggttcct tcaacaaagg ccatcagttc tccttttttt gtccgaattt
     5461 ctctaacttc cttgatcatc actaataaat tgactggttg attagggacg atatctgtaa
     5521 tcagctgaac ttgtttagct aaacgaagac gatcaaaccc ttctgcagga tgacctgaca
     5581 aataaatacc taagtactcc tcttccagct tcaagcgttc ttctagtgta tagtcagcga
     5641 cttcttcttc ttttaatgcc atgattccca gcaagtcaag acttccacca ctgtaaacga
     5701 tattttggat ttttccttcg agatcaagca tcaattgttt cctgttagga gataattcat
     5761 caaaaactcc tactgctgtc agtgattgca gtaactctaa tttcagccaa cgcttatcga
     5821 tccgtatgag gaattgatcc actgactgga acgggccatt ttgttttctt tcgtttaata
     5881 tatcttctac aaaatcacgc cgaatacctt ttatcgctgt cagtccgaat ctgatttctt
     5941 ccttattgac caactcaaaa ctggaattac tttgattaat ggacggcgag gaaagtttga
     6001 gtttattttt acgtgcttct gcaatatatt ctttcaattt tgatgtgtta tgccgaacag
     6061 aattcatcag gctggtaaag aaagcacctg gatgatgggc ttttagatac gccatttgga
     6121 atcccacgaa tgaataagca aatgcatgtg accgattgaa tccatagttt gcaaattttt
     6181 cgatatattc atatacggtc gctgctgttt tttccgaata tccctgttgt aatgctcctg
     6241 atacaaaatg cgacttttct tcatctaata cgtctttttt ctttttactc actgcccgtc
     6301 gcagaatatc tgactgccct aatgtaaatc cagccatagt cgaggcgatc tgcatgattt
     6361 gttcctgata gacgatcact ccatatgtgt ttttcaaaat cgggatcagt gaatcatctg
     6421 ggtagcgaat ggcttctttt cctttcttcc tggcaatgaa ggtatctata ttttgcatag
     6481 ggcctggtcg atacaatgca ttgactgcgg caatatcttc gatgttttct ggatctaatc
     6541 ttcgtaaaac gttccggata ccagcagatt caaattgaaa tactcctgag gtttcgcctc
     6601 gttgaaacaa gagcagcgtt tttgcatcat ttagcgggat ctcttttaat cggatctcat
     6661 acccttctac tcgcttaaca gctttcaaag taaaatcaat aatcgataag ttgcgtagtc
     6721 ctaaaaagtc cattttcaaa agaccgattg cttctacctc attcatcgta tactgggtca
     6781 gaaaagcttc atcagaaccg cgttggagcg gaactagttc aagtagattc ttatcgctga
     6841 taactacacc tgctgcgtga gtcgaaacat gtcttggcaa tccttctaaa atcactgcag
     6901 ttttgaataa aagttggttt ttttcgcttg cctgaactaa ttctactaat tgatgcgaag
     6961 ttttataagc ttgggtcaat gtgattttca attgattggg tattgctttt gaccagcggt
     7021 ttgcttcact ttgcgataaa ccaaacactc tagctgcatc tctaagaacc atttttgctg
     7081 ccattgtgcc aaatgttgcg atttgtgcca tatgatattg tccatacttt tctcgaacat
     7141 aattcaatac ttcttcacgt cgattgtcag gaatatccaa atcgatatct ggcatcgtaa
     7201 agcgttcggg gtttaaaaag cgttcgaaca gcaaatcata ttctaatgga tccacatctg
     7261 tgatttctaa cacataggct actaatgaac ccgcagcaga accacgacct gcaccggtaa
     7321 cgattttgtt tctatgagca aaagccatta catcccatac gatcaagaaa taatcatcga
     7381 atcccatttg atggatgaca gataactcgt agtccaaacg ttcttggtat tcctttgtat
     7441 agtcagtgat tcggcgttcc acttgcgaat agcataactc tcttaaatat tctccagctt
     7501 gttttccatt aggaactgga taatgcggaa gtaatttctg atggaactgg aattcaaatg
     7561 aaatcgattc agctaaacgc tgggcgccta ttacagcttg ggaaagaccc gctttttcga
     7621 atcgtttgat catttcttgt tctgaaagaa gatagacatt tgctgttagt ggtaaagatg
     7681 cagataaatt ttctaaaggt atttggcttc cctctttgat atgtttcatc acttcaagtg
     7741 caaaaagttc ttcttgttgt aaactagcga tgggatgtaa tgcacaaagc gaataatttt
     7801 cttttatcac atactgatac cattcaggca attgatcagg cgtgttttct gtcaagccga
     7861 tataaaaatt tctagtaaaa acattttcaa gtaaaaactg ccaatgaccg aaaaagttat
     7921 cctctttatt gaaagcctca gaaacagaat gatttgccgg aacaacaaac gctagatggt
     7981 cggtttctgt catttctgca agttccaatt tttcttggat catttttcgg ctggaaagtt
     8041 tcatcagctg ctgataacct atttcatctt ttgcgtacgc aagcaagcca taattttttt
     8101 cttcataagt ataactaaga tgtaatccaa tgattggctg tactccttct tctacacaaa
     8161 tacgatagaa ttcaggtgca ccgtataaga catctttatc cgttatggct aatgaagtgt
     8221 agccttgttt ttttgcttct tgtacatatt ctcgaatacg tatcgtactt tgtaaaagag
     8281 aataagaagt aattgtataa agttgtggga aaaacatctt gcattccgcc ttttttttcg
     8341 ttaaaattca ctagcgttaa aaggtttgat ccttttactt tcattaagat agcaggcgct
     8401 gaagttgatt attccacttc atttgcttgc ttgtaatctg taggaatgag ttctttcgca
     8461 agaactcaaa ttttattgag atttggtctc gtttctttac attcaaagaa aatctggtaa
     8521 aattaagata gaaaagaggt gttctttatg cgatatatcg ttacattatt ctgggctgtc
     8581 gttctaggtc aagtagtcgg ttatattggt gctgcattaa caagcggaac atatgatttt
     8641 actttgacaa caatcatttc attcattgcg ggtgtcatta tccttttgat tggtgcagtt
     8701 gcgccaagaa aagaaacctc tgcccattcg taaaaaaaca gccaagagct tgagatttct
     8761 caagctcttt tttattttct actcctcacc accattataa tctgctgcga agaactttac
     8821 gaaagttgaa taaagaaaga agaatatttg acagaacaaa caaacttgtc acaataaaaa
     8881 cagcactgta attataagca tgcgcgactg tcgatcctag catgggacct aaaacttgtc
     8941 caaagttgct aaacatctga ttgtagctat agattcggct gactccttct tgaggcgtaa
     9001 tcttactgat cagtgtattg acagaaggca tcaaagcgcc agttgaaaag cctaaaataa
     9061 agcgaagtat acctaattgg agcggtgtag tgacgaatgc cataggtaaa taacagcaaa
     9121 atgataaaat gagtcctcca attagaactt tttgattccc aatcttatcc cctagttttc
     9181 ctagtttcgg tgaagaaaag acagcggaaa caccagctat cgaaacaatc aagccgctga
     9241 caaaaaggat attttctgta cttccgctca attcacgaat atataaggtc aaaatagggc
     9301 tgatcgtagt gattcctatc tgtaaaatca aggtcgtaat gaagagaccg atcaaaatag
     9361 agagatgatc catttttgaa aaaatttctt tggtgcttat cagatctttt ttctcgattg
     9421 gatggaaatc ttctttgact aagaaaatgg tcaataccgt tgtgatcatc aacaaagccc
     9481 ctgtgatcaa gaatacattt tccataccaa accactgagc cagtgcaccg cccattgaag
     9541 gtccgatcag atttccagca atcgctccgg tagacaatgt tcctaacgcc catccgctct
     9601 tttctctagg tgcctgtgaa gcaatcatcg ctgtggcatt tggaatatat ccagacaaaa
     9661 tcccattcca aaaccgcatg atcaaaagcc aatacgcgtt tggtacaaaa gccaaagatc
     9721 ccattgttaa tgtcatccct gctgctgcac ggatcatcat gagttttcgg ccttttcgat
     9781 cagctagatt tccccagatt ggtgcaacca cggcagatgc aaaagcagtc acagagattg
     9841 ctagtcccga aaacaattcg atttgatctt ttggtgttcc tagttgctca acataaactg
     9901 gtatgaatgg cataactaaa ctaatacttg caccagtgaa aaaacagcca atccacgcaa
     9961 tcactaaatt ttttctccaa ttaatctcca tctatcatcc ctctttcgtc tcttttatca
    10021 tacctatttt cgaataaaca agcaacgatc tcgccagtaa aaagagaaaa atcccgcaaa
    10081 ggtcatttta tatgtaacgt tctttttatg taaaacaaaa agagatcaga acaaatactg
    10141 ttccaatccc ttctctttag ttaaattgtt gctagaatga tgaagttgat aatgaataaa
    10201 atatcaacga tccacaaagc aacagaaact tgattgtatt ttcctttgat tactttcaca
    10261 attgtataga aaataaatcc tgctgcaatc ccataggaaa tgctatagca caatcccata
    10321 aagatcgatg caaagaaggc cggtaaagct tcttccatat ctagccattt gatgtctgca
    10381 aaagaagcca tcatcattac tccaactaaa atcaatgctg gcgcagttgc ttgatttggt
    10441 acaatggcga tcagtggaga gaataaacta cttaatgcga atagcactgc cactactact
    10501 gaagtcaaac cagtacgtcc accggccccg atcccagctg cagattcgac ataagttgtt
    10561 gtattcgatg taccaaagat agcccccaca gaagtagcga tcgcatcggc aaatagtgct
    10621 ttatccattt ttgttttgaa cccacgacca tcttccaacg cgatctcgtc ttcttttgag
    10681 aaaatacctg tgcggcgtcc tgtaccgata aatgttccga tcgtatcgaa agtatcagat
    10741 aaactgaatg cgatgatcgt catcaatact tgaggaatct tggaagaatc actgaataaa
    10801 gattgcatgc cttcagaacc aaatgctgca ccgaaagttg ttcctaattc tttaaatgaa
    10861 ttacctaacg aattcgtttg ccaatcaatg gaacttaaat caacaacacc cataaaaata
    10921 ccaaggactg tggtcgctac gataccgata agaatagccc cacggacatt ttttacaact
    10981 aaaatggctg tcagtaccaa accaatcaca gccaataaga taggagcgtt gtcaaagttg
    11041 gctaacgcag ggacgattcc accatttatc gtaacatttg tcgcttttcc gccttcaacg
    11101 acagagctcg aaatagctga ctggtctgct gaaaaagata agaatcctgc atttttgatt
    11161 ccgacatacg caacgaaaat accgatcccg ccaccaatcg catgttgaag actttcggga
    11221 atcgcccgaa taatcatttt tcgaatattt gtgacagtaa taaaaatatt gattaatccg
    11281 caaataaaca ccattgccaa ggcttgttgc caagaataac caagcccaaa aacgaccgta
    11341 aaagtgaaaa atgcgttcaa tcccatacca ggtgcctgag catatggtac atttgcgaac
    11401 aatcccatta ccagcgtacc aataatcgat gcaatgattg tcgctagaaa tactgcttgg
    11461 aagggcatac ctgatgctga caaaatcgtc ggatttacga ataagatata actcatggca
    11521 aagaatgtcg ttactcccgc cattatttca gttgatacat ttgtattgtt tttctttaaa
    11581 ccgaaaaact tttccataaa aagttccact ccctgaattt ttttctgatg gaaaactata
    11641 ataataaaaa ataagtaaaa tagggcaaat ccatcgaaca atttcaaatt atatagacgt
    11701 ttcattcgct tttcaacgtt tttttaacaa aaaaagcaaa aataatactt aacgttcgtg
    11761 tttagcttat gtttagctat ttatatagcc ataactgtag tttttgttag gaatagctga
    11821 ttgctcttgt taattaccta aaatatgcta gactaaaaca aatgctagtt gaggaaggaa
    11881 ggacccttat tgaataaaaa attaattgcc atcgatctgg acggaactac cctcaatcaa
    11941 gattcgatga ttacatctaa aacaaaagag actctaaaaa aagcaatcaa tgccggtcat
    12001 catgtcagta ttgctacagg acgcccattc cgaatgagcc atcagtttta ccaacaatta
    12061 gaattaacaa caccgatggt taattttaac ggcgcattag tacacatccc taatcagcac
    12121 tgggatggtg aaagagaaac gttgatcaat cgtgaaatcg cttttgaaat cttatcgcaa
    12181 aaaaagcagc taaatttaga ttttatcgct gctgaaaatc gtgatacttt ttttattgac
    12241 agttttgatt tctttgatga aaaaattttt gcttcttctc gtccaggaga gaagaatttg
    12301 ctttctccta aaaatttgac gacaaatcct acatctttgc ttgtccgaac agacaaacgt
    12361 tttgcaggag ctgtatctgc tgaattaaca cgtcaatttg gcagttatgt cgatgttcgg
    12421 acatggggtg gacctactgc catcttagag attgtttcaa aaggaatcca aaaagcaaaa
    12481 ggcgtgcaag agattgctaa ctacctgtct atcgatcaaa aagacgtcat tgcctttggt
    12541 gacgagcata atgatttgga attgttggat tatgcaggtt ggggagtagc tatggctaac
    12601 ggtactgacc aactcaaagg cattgcaaat gatgtcactc ctttgagcaa tcaggaagac
    12661 ggtttagctg tttatctgga aaaactactt aaactataat agagaattag attccacaaa
    12721 aaagaggttg tgac
//
LOCUS       DADQDV010000079        12432 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.082, whole genome shotgun sequence.
ACCESSION   DADQDV010000079 DADQDV010000000
VERSION     DADQDV010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12432
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.082"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..190)
                     /locus_tag="J8S10_002456"
     CDS             complement(<1..190)
                     /locus_tag="J8S10_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631023.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGC"
     gene            complement(200..1015)
                     /locus_tag="J8S10_002457"
     CDS             complement(200..1015)
                     /locus_tag="J8S10_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAZ9631024.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            complement(1277..1720)
                     /locus_tag="J8S10_002458"
     CDS             complement(1277..1720)
                     /locus_tag="J8S10_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HAZ9631025.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            complement(1854..2192)
                     /locus_tag="J8S10_002459"
     CDS             complement(1854..2192)
                     /locus_tag="J8S10_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAZ9631026.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            complement(2180..2557)
                     /locus_tag="J8S10_002460"
     CDS             complement(2180..2557)
                     /locus_tag="J8S10_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAZ9631027.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKEIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            2781..3974
                     /locus_tag="J8S10_002461"
     CDS             2781..3974
                     /locus_tag="J8S10_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAZ9631028.1"
                     /translation="MTTYQRKVLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            complement(4140..4562)
                     /locus_tag="J8S10_002462"
     CDS             complement(4140..4562)
                     /locus_tag="J8S10_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAZ9631029.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            4957..5151
                     /locus_tag="J8S10_002463"
     CDS             4957..5151
                     /locus_tag="J8S10_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631030.1"
                     /translation="MVAGSLLSGCGATTSTTQSTSSDQASSSSTTISESTADSSKEQE
                     QIEKKKEEKQKAEKAALEKK"
     gene            5148..5594
                     /locus_tag="J8S10_002464"
     CDS             5148..5594
                     /locus_tag="J8S10_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631031.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQEAIAQQQAEQARQQSA
                     AEQASQQAQAAAPEQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLS"
     gene            complement(5804..6976)
                     /locus_tag="J8S10_002465"
     CDS             complement(5804..6976)
                     /locus_tag="J8S10_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAZ9631032.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(7182..7997)
                     /locus_tag="J8S10_002466"
     CDS             complement(7182..7997)
                     /locus_tag="J8S10_002466"
                     /inference="COORDINATES: protein motif:HMM:NF033902.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAZ9631033.1"
                     /translation="MTGFDENTGVALYDPAESALTFTTDTEGSISVNGLIDGNYTLVE
                     TKAPDGYQLTNPQKETTFIVKNGKLQQTTGIIHGADEANLGNPNGVVNRENTTTDNTI
                     TVENVQNYGDFHFIKQDVNTQEKLADAEFSILRAKDPTVKLMKKIANLASGEYPYAWS
                     DEVTGSDWEEVKLISDSEGKFSIEGLKQGAYCLQETKAPEGYALPKNEAAYTEFTVDD
                     DPTTSDETTIDNQPKGILPSTGGMGIIVFILVGTALVGGAVIYFKKRHQETEA"
     gene            complement(8147..8593)
                     /locus_tag="J8S10_002467"
     CDS             complement(8147..8593)
                     /locus_tag="J8S10_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HAZ9631034.1"
                     /translation="MKNIKTKIWTFLGTAIMLLPFVLGLGTAEVSAAVSPTPENVTVN
                     LHKLKFTSAPENQINNGTELTFPNSEPLNGVEFNVYDITATYYPSKDTAVPADATPFA
                     SVTTSGEGLANLTLPGKSDGKDAVYVFVETPKPGVETSPNIVLSLP"
     gene            complement(8590..9594)
                     /locus_tag="J8S10_002468"
     CDS             complement(8590..9594)
                     /locus_tag="J8S10_002468"
                     /inference="COORDINATES: protein
                     motif:HMM:NF037639.1,HMM:TIGR04226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HAZ9631035.1"
                     /translation="MTDSSNHKLTTIHLYPKSEQKIPAALTLTKTVENKQTDFADGDK
                     VPYLITVTIPENINEIGTYTIKDTADPQLWLEPETIDFLIGGDKIHTFHTQKIKHGFV
                     LSDSGKDLSSFAGKKLTIRYQMTLKENSEKTTFDNDVRLTTDNQTVETHLAIQTGGKQ
                     FVKVDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFTSSKDGTFSVHG
                     LSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEPKANPTNNGKTP
                     VQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKKQQKGNNRREIK
                     "
     gene            complement(9634..9963)
                     /locus_tag="J8S10_002469"
     CDS             complement(9634..9963)
                     /locus_tag="J8S10_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HAZ9631036.1"
                     /translation="MFESDKMPSISQNDGINIPDNFQGVKGLNGVTFAIYDVSDEFYK
                     LRSEGSSVEDAQRKLAQKSDSEKILAENVTKTVDEEEGIASFSASDKDEQGRDAVYRF
                     TEIKTSD"
     gene            complement(10089..12416)
                     /locus_tag="J8S10_002470"
     CDS             complement(10089..12416)
                     /locus_tag="J8S10_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAZ9631037.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSAIETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
BASE COUNT         3513 a         2430 c         2272 g         4217 t
ORIGIN      
        1 tgcaacctgg accaataaaa agtaaagaaa aaataaagga aaagacattc cttccatcta
       61 tcgacaaaag gaacgcagct gctatataca agatattgac acaccaaaaa caaaggctac
      121 ttgccaatga ttgatacaac caataaaaga attccatata aacatttttg tcaaaacgct
      181 gctctttcat aatcacctcc tattccttca ttcctgatga agcgatccct tctacaaaat
      241 atttttgcat cgctaaaaat ataaaagcaa caggaagaac agaaacaact gaggcagcca
      301 tgattaatgc gtactctgca tcaaatagcc caataaacat tttcaaccct aactggattg
      361 ttttattttc cgtagaagac aaataaatga atggccccat ataatcgttc catgtattaa
      421 cgaatgtgat gatcgtcaaa ctggcaatcg ccggttttgt aagaggtaaa atgatcttgc
      481 gatagattcc ccactctgat aagccatcga tccgcgcact ctcacataaa gaatctggga
      541 tactactgta gtattgcttc aacaagaaca caccaaaagc attgaacgct tgtaatagca
      601 ccaacgacca caacgtatat gttaaaccca cttttctcat cataatgaac tgcgggatca
      661 tataagactg ccaagggaca gcaatcgtgc cgatatatgc taaaaataaa atatcgcgcc
      721 ctttaaaatt tagtttagaa aacccgtaag cagcaaaact agaagtaaac aactgaatca
      781 acgtgatcac aacgcttaaa aaagctgtat tcttaaaaaa tgtcactaaa ggaatacgag
      841 accaaataac cagataattc tctaaatgcc aagttttagg gatccattga atcggaatcg
      901 tgaacacttc attatttgct ttgaatgaag cagaaaccat ccataaaaaa ggaatgatcg
      961 tcaataaagc taatacaatc agcagaatca tacccaacca ttgaataaag ggcatgtttt
     1021 ttgaacgaat ttttgctttt tttctttcat ttcgaacacc tccaaagtta taatcttcat
     1081 ttctttgtaa tgattacaat ccagaacaac ggttattata gctgattcat ttccgttctt
     1141 cttatgtttg taagcgctta tttaacaagt tatgtaaatc tctttatttt ttttgattta
     1201 aaaatgaaaa aatacaaaag caagactgtc atacgtctcg cttttgtatt gaaatttctt
     1261 cgattagaga tacttattac tgttcaaaag cttctttgaa acggtgaatc aattcattga
     1321 ctacaggtga taaaatccga ttctttttcc agactagcat gcagttcgtt tcaatcattg
     1381 ggtcaagcgg aacgaatgtc actcgctttg aaagatgact tacagcacct tctatgacta
     1441 aagcagcacc tacctgattc tcaattagcg caaatacatt gaaaatcaaa ttgtacgttc
     1501 ctgtgatcag caactgctcc ttttttatgc ctaaccagtc agcaaacatt cgctgtattt
     1561 ctggacgctt tgagatcaaa agaggtacat tcgcaaagtc ttcttttgtt atcacgtctt
     1621 tttttgctaa aacagaattt tctaaaatga gcaatcccca tttttccttt cttggtaaca
     1681 aaatcgtttc gtatttctct gtatctactg gatctagcaa aatcgctaaa tctaacaggc
     1741 ttttttctag tcactccgtg atatcatcac ttgttccgct gtggatatga aattgaacgc
     1801 tgggataatc acggatcaac ttttctagta atagtgccaa tgtattcgaa ttatcagctt
     1861 ccacacagcc gatcgtaaat cggccgctga ataattgttt ttttctgttc tcgaattctt
     1921 gagtggtttg attcgttaaa tctaaaattt cttctgctcg gcttttttag aaaataacct
     1981 gcttctgtca agatcatttt gcggttttcg cgtacaaaca gttctgttcc tagttcctct
     2041 tctaactcct tcagttgtcg gcttaaggtt ggttgtgtaa gatgtagaac ttctgcggct
     2101 tgagagattg ttccttcttc tgcaattgtc caaaaatatt ttagtaagcg taactccata
     2161 gcgatgctcc ttgatttttt tacttgatac attccatttt atttctagat aacacacgat
     2221 catatttctt gatttttcct tgtaaacgtt ccaaacactc ttgcatttca gcaatttctt
     2281 tcgtcaaaag ttcactttct tcaatcaaaa gcttacgccg ctcaaataca gttgcttctc
     2341 cttcgctaga taggcgaata tattcaatca aagactcgat cgataatccg gcatttcgca
     2401 tacagatcgt aaagtcgacc cattttaggt cttcttctgt ataatcacgg attccgcctt
     2461 ttgtccgatt aactggtgga atcaacccga ttcgttcata atagcgcaat gtatcggccg
     2521 aaatgccctt ttcttcactg acttgtttga tattcatctg atcactcttt ctcttaattt
     2581 cttgccactt tacttatgta ttttatttat tctacaactt taagtgtact ccaagtcaat
     2641 actcatttct attaaaacta agctggatta tctatatcgg ttgtttgtgt attatttcaa
     2701 ataaaaaagt cttgtttttt tattcttttt tggatatact tttaacaatt tagggaaatt
     2761 ttaggaaaag gggtataaaa atgacaacgt atcagcgaaa ggtattatta tcgacatcgg
     2821 cgggaattgc tttagagaat atggatatta tgtttttagc tttttcatta tcttcaatga
     2881 ttacttcttt tcatattagt ggtacgcaag cgggtttcat ttcaacgatc actaatttgg
     2941 ggatgctcat tggaggtatt ttttttggca tcatagctga taaatatgga cgtgtgaaag
     3001 tattttctca aacggtcctt ctgttttcga ttgcttcttt attgatgtat tttgcttcaa
     3061 acatctactt ggtttatctc tttcgcttta tcgcaggtgt aggagcggga ggagaatacg
     3121 gggcgtgtat gtccttgatt tccgaaagtt tttcaaaaaa acaaattgga cgagcttctt
     3181 cggttgctgg tattggtgcg caggtcggtg cggctttggc tgcgatttta gctgctgtga
     3241 tcattccaac gtttggttgg aagatgttgt atgtcgtagg tgtactgccg gtgttgatgg
     3301 tcttgttcat tcgtcgcggc ttgactgaac caaaggaatt caaatctgta caatctgccg
     3361 aaaagaaaac caaacttagc agactgtttg aatcaaaaca tcttgcttgg caaacatgtg
     3421 gccttagtat catggtaact gtccaaattg ccggctattt tgggttaatg aattggctgc
     3481 cttcaattat gcaaaatcga ttagggcttt cggtttctgg gtcttcattg tggatggtca
     3541 gtactatttt aggcatgtct ttggggatga tgacttttgg cataatcatg gataaattgg
     3601 ggcctaaact agccttttct ttgtttttaa tttgttcatc cttatctgtc tatctacttg
     3661 tgttagccca tagccagtgg agtttggtag cagccgctgt gatagtcggc tactttatca
     3721 atggcatgta tggtggatat ggcgcagtga ttagtagttt gtatccaaca gaaatccgcg
     3781 cgacggcgaa taatttcatt atgaaccttg gacgagctgt tggtggtttt tcttctatcg
     3841 tcatcggttt cttgatggat cattatagtt taactgccgt aatcttgttt ttgagcggta
     3901 tttacctagt cagtctgctg gtcttgacaa ctcttactgg tgttacagca ttaagggaaa
     3961 gcttgcagca ttgatagttg agtctgtaaa tgacaagaaa gaggtgtggc aaaagcttgc
     4021 atctgcggta ataagaccag ccaaatcaaa aacatgagac actgtttccg tttggctggt
     4081 cgtattactt gatgcagggc agctttttca actgctaatt tccttctatc tggcggcgac
     4141 tattctttga cgtccgtcat ttcaaagtac tttactaata acttagcata acgaaaaact
     4201 gtggatacac tcgtatattg agcgtctgca taatcttcca aatttttctc aggatgttga
     4261 tacatgaatt caatcaaatg ataattatat gattttctgt agaaatgaag ataaataatg
     4321 tagattggga agttctcctg cttttccata gaaaagcgcc gattattctc attcttcaaa
     4381 atgaccttat caggatattt ttggaacaat tcttctaaat ctgttagata attcaagata
     4441 gacttacttg ataccttcaa ttcgttttgt agttcttcta ttgaacacca acgttctgtt
     4501 tcaagcagta aatgaatcat tttaattttc ttttgagaaa cttttgttaa aaaagtctgc
     4561 atattttctc ctcctgtatc tactttacta tactacatac aagaaaaaaa acggatacaa
     4621 atatcatatt gtcacaccgt caatagtgca taaacctgtt attatttctc tttttttcct
     4681 aagtattcta ttgatatgaa tcatttaatc gtttattata taaatgtcaa taatctaata
     4741 ataaaataac gtacatattt tattattgca tacttaataa cagaactata gcaaaaaatc
     4801 ccgtgtatca acacgggatt agattaagtt tcctcaatca ctattcataa cacaattatt
     4861 ataacaagta agtaaacaat tgaaaaggac atttattgaa aacggttgtt ttttacttaa
     4921 ggaggaaatt tagcgaaaaa attagttgca ttgtttttgg tcgcaggaag tttgttgagt
     4981 gggtgtggtg ctactacgtc tactactcaa agcacaagtt cagatcaggc ttccagcagc
     5041 agtaccacga tctccgaaag tacggcagat tcatcgaaag aacaagaaca aattgaaaag
     5101 aaaaaagaag agaaacaaaa agcggaaaaa gctgcactag aaaaaaagtg acagaagcgg
     5161 aatctgcttt gtcacaagct gaagcaaatc ctacaaaaga aaactatgca actgcttcag
     5221 cagctatcca agcgctacct gaaaacaaac aagagttgac aagccgtctt gctgcaattg
     5281 attccacaat caaagcaaaa gaagcagaag aagaacggaa aaagcaagaa gaaattgcac
     5341 gacaacaagc agaacaagcg caacaagaag caatcgcaca gcaacaagca gaacaggcga
     5401 ggcaagaagc aatcgcacag caacaagcag aacaggcgcg acagcaatca gcagctgaac
     5461 aggcctctca gcaggcacaa gccgcagctc ctgagcaaaa taatgaacaa actgtctatg
     5521 tcacaccgac cggttcaaaa taccatacac ataaatgtgg aaatggtacg tatacccctg
     5581 ccactttaag ctaagctcaa gctcgtggtt taaccccttg ctccaaatgt tatggaaact
     5641 aattcaaaag ttatactata ataataaaat tcttctgaaa cataaaaaaa tagaagatgg
     5701 cgttccagat agtaaaccaa aaataacagt ttacacgtcc atttcgtcag cttctctctt
     5761 ttttcattta gtctgttccc tctgcttttt tggacatctt cattcattct ttctcaatca
     5821 aatagtacac ctctttttct tttcgcagtt tatatcttcc ttttttcaat ttcattgaaa
     5881 actgtttcga atgtttatgt tttacatgga ttttaagcag gagctcctca tgttgcaagc
     5941 gatagttcct gccttttaaa tcagaaaatc tcactagtcc gtattcatca gaagctttca
     6001 caaatggaac tttttctcta gtaatatagt gtttgccgtt gagcgttttt acagaaaaga
     6061 ccattccttc gattggtcgt ccgtttgtgt tctttacata aaaagataaa ggatagtttc
     6121 gcttagcgat ggccaaagaa tctaaataag cgatgagtag ccaaactaag ccgattgatc
     6181 caagtagtat accgataaac caaataaaaa atttccattt tttccattga tcaattcctt
     6241 ggatcgcttt ttttgcctct tttgcttgat aaggaatacg atgccccgtc acaagcagtc
     6301 gatgtgtatt gaccatataa ggagtacagg taagcaaagt cacgagatct ctgccttttt
     6361 ggatacccaa agaatctact tcatcaggta agaccacttg gattttttct acttgatacg
     6421 ccaatgtctt tccattgatc tggatgaaaa actggtctcc ttttttcaac ttaggcaaat
     6481 ctgtaaataa ttttgcttct gggagtccac gatgcccaga aagaacggca tgggtgtttt
     6541 tcccgccagt cggataagaa ctttcttcca ataatgacgt tcctttttgc aaaaatattt
     6601 ccgttgtctg atcgaatata ggtaagctga cattgatttt tgggatttcg atgactccaa
     6661 gcatatgttc cataaaaaag gcattactag gtaaatcttt taatgctttt gcatcaactg
     6721 cttggttgaa actgcctatc cctggtgata cgttttgctc tgccaactgt tggtttttct
     6781 ttgtcatttt ttcctgctgt ttttttattt cctctgaatt cttattcgat gcttgctttt
     6841 gataatggat gatcatttgc tgggcaagaa aatcattcag tgaatcttct acaaaaggat
     6901 aagaaaagat cccgatccca acgactaaaa tgattgccat gaagatgtcc agtattctta
     6961 ttctgctttt attcatcatg tccacctatt ttctaatatg tatatgaaga ggttgtgaaa
     7021 tcagcgcctt gacctgagta ttagcgaagc aaacggcaaa atagttcctc ctattttgcc
     7081 gtttgttgag cgaataccaa gagaccgacc acttgtcaca acctttctcc ccatttgaat
     7141 cactatcgtt tatttatcgt atgatttttg tttccaatag tttaagcttc tgtttcttga
     7201 tggcgttttt tgaaatagat cactgctcct ccaactaaag cagtacctac caagatgaat
     7261 acgatgatcc ccataccacc agttgaaggc aagattcctt taggttggtt atcgatcgtt
     7321 gtttcatcag aagttgttgg atcatcatct actgtaaatt cagtgtacgc agcttcattc
     7381 ttaggtaatg cgtagccttc tggtgctttt gtttcttgaa ggcagtatgc cccttgtttc
     7441 agcccttcga ttgaaaattt cccttctgaa tcagaaatca atttcacttc ttcccagtca
     7501 gaacctgtga cttcatctga ccaagcatat gggtattctc ctgaggcaag gtttgctatt
     7561 tttttcatta atttaacagt tggatctttt gctcttagaa tagaaaattc tgcatcggct
     7621 aatttttctt gcgtgttcac atcttgtttg atgaagtgga aatcaccgta gttttggaca
     7681 ttttctacag taatcgtgtt atccgtagtt gtattttccc gattgactac accgtttgga
     7741 ttcccaagat tggcttcatc tgcgccatgg atgataccgg ttgtttgttg caattttccg
     7801 ttttttacta taaaagtagt ttctttttgt ggattggtta attgataacc atctggtgct
     7861 tttgtttcaa ctaaagtata attgccgtct attaatccat tgacactgat ggatccttca
     7921 gtatcagttg tgaatgtcaa cgctgactca gcaggatcat agagagcgac accagtgttt
     7981 tcatcaaaac cggtcacgaa ttgattctct gaatttttga tctggaattg cgcccctgct
     8041 aacttatcta cccctgaaaa gttcccagct ttctggattt tgatattgct ttctttgatg
     8101 acatttttag catataggtg aatcgtgtct aaaggtttgt cagggtctag ggtaagctta
     8161 acacgatatt tggcgacgtt tcgacaccgg gctttggtgt ttctacaaag acgtatacag
     8221 catctttccc atcagattta cctggaagag tcaggttagc taatccttca ccagaagtcg
     8281 ttacacttgc gaagggtgta gcgtctgctg gaactgctgt gtctttactt ggatagtacg
     8341 tagcagtgat gtcatatacg ttgaattcaa cgccgttcaa cggttcgcta ttcggaaatg
     8401 tcaattccgt tccgttgttt atttgatttt ctggtgctga agtgaatttc aatttatgca
     8461 aattaaccgt aacattttct ggtgtaggtg atacggctgc agaaacctct gcagttccta
     8521 ggccgagaac gaaaggaagc agcatgatag cagttcctaa aaacgtccat atttttgttt
     8581 tgatgttttt cattttattt ccctcctatt gtttcctttt tgttgttttt tataaaacca
     8641 agctgtccct gttgaaagga ctagcaataa ccctaaaatt gagaaacctc caagcatctc
     8701 ttcgcttgtt tttggaaagc ttcctccatt tttttcattt gatggaccat ttgtctgcat
     8761 ctgaactggc gtttttccat tattcgtcgg atttgctttt ggttcgttga tgatttccaa
     8821 tggtatagga tgaagcggat cataactgcc tttttcaact tcaaagagaa tggttgattg
     8881 actcaatata tatcctttag gcggtttaat ctccactagt tcgtaacttc caaaagacaa
     8941 tccatggaca gaaaatgttc catctttact ggaagtaaaa atcgttgctc ttgaatcatc
     9001 tttggctacc caatgattta tcccgttttc ttgcgctaag tattggtcat tttttttgac
     9061 tagaaattga gcatctgcta gtttttgttt cgtttgccga tccactttga caaattgttt
     9121 gcctcctgtt tggatggcaa gatgtgtttc tactgtttga ttgtcagtcg tcaaacgtac
     9181 atcgttatca aatgtcgttt tttcactgtt ttctttcaat gtcatttggt aacggatcgt
     9241 taattttttt ccagcaaacg aactaagatc ttttccagaa tctgataaga caaaaccatg
     9301 ttttattttt tgtgtgtgaa atgtatgaat cttgtctcca ccaatcaaaa aatcgatcgt
     9361 ttctggttct agccataact gaggatcagc tgtatctttg atcgtatagg ttcctatctc
     9421 gttgatgttc tcaggaattg ttacggtgat gagataaggg actttatccc catctgcaaa
     9481 atctgtctgc ttattctcta ctgtttttgt taatgtgagt gcagcaggta ttttttgttc
     9541 gctctttgga tacaagtgga tggtcgtcaa tttatgatta gatgaatctg tcacaggaag
     9601 cacaacgaca aatggtgctg atttttcttt tacttaatct gaagtcttta tttccgtaaa
     9661 tcggtaaaca gcgtcacgac cttgctcatc tttgtccgat gcactaaaag aagcaatgcc
     9721 ctcttcctcg tctactgttt ttgtcacatt ttctgccagt attttttcac tatcactttt
     9781 ttgtgctagt tttctttgtg cgtcttccac actacttcct tctgaccgca gcttgtaaaa
     9841 ttcatccgag acatcatata tagcgaaagt aacgccgttc aaccctttta ctccttgaaa
     9901 gttatccggg atatttattc cgtcgttttg actgatactt ggcatcttat cgctttcgaa
     9961 cattcgatta tgcaaagtaa atgtaatagg tgattctcta gctgacacag tcggagaacc
    10021 tataaaaaag accagtagga taaaaaagag aacagcaaat atatccacac gtacattttt
    10081 tgtttttttc atcgctgttc acctgctttt ttcttacgat ggataaaata aaagaagcca
    10141 gaaaaaataa agatcagtcc taaaaagaca aagggcagta gacctatccc acctgtcgaa
    10201 ggaagcaaga gagtcggatt gatcgtcaac ttagcggtat ctgttgcgat aatcgtataa
    10261 ttattgttta cacttccttc gcctaaacta atcgttacta tttgtgatcc aatatctgtc
    10321 cggctgttaa ctgttagggt ataatccaat gattcgccta agacaacacc ggtaacgtgg
    10381 agatttccaa ccgaaatcga gtgactttgg gcatcataat taaaggcagc gtcatcgaca
    10441 gtaatcactg cgttagcttt atagatggta taagttcctg atgtgttggc tatatcagta
    10501 aatgacaact tgggatttgc tgctttgact ttgtctattc cgctattcgt tagtttaatt
    10561 gtatagctgc cagcattaac catatttttt gctgattgtg catctgctgt gtaatccata
    10621 ctgctaagtg ccacttgtac tggagtaagc gaactagtga caccctctgc tagcttgaca
    10681 tggattgacg ggacacctgc ttttccatca tatgtcttac tgccactgag ctctaccgca
    10741 ccgctgattt gcttaatcgt atagacatca gatgtctgca cgatagtaaa taaatagttt
    10801 gttctggcag ctagtttagc tagtccgctt tttgtcaatt gccaagacgt ataggttcca
    10861 atttcagtag gcgcagttac ttcaactccc ttttcattca tcgctttgaa atcagttgga
    10921 ttccatgtga tttgatcaat actgagatca ttgtttaaaa gggatgttga ttctgtttta
    10981 tcattaaagg catatttaac gatcggtaca acagaaagac catcatagta cttactgcca
    11041 tttgcattga ttgatactgt tgcatttgtc ttataatata ggatgacttc agaaatctgt
    11101 tttccatttg cgtcctttac gattacattt ccatttgtat ctaaactagc taaaacactc
    11161 attgctgatt ggttctttgt ttctatcgct gaaacagctg taaaggtata tccgttgata
    11221 gtaggcgtat tagtcgtcag gtcttgtgca gcacttccgt aagtaagatt cattatttta
    11281 gaaggagcaa tcatctgtcc aaaatagtct tgatacttaa tagtgattgg tgtttgtttg
    11341 cctgtatagg tcaccgtatc gacgttactt tctagggctg tgaaagaacc gtttgtttgt
    11401 gcaaaagaat agcccgttac tgctgttgga gtgataacca ctttgtcacc cacatggatt
    11461 ccagataatg tagtcccgta cgttccgatt tttgctgctc caccattgac tgtataagaa
    11521 aaagttcctg tccgattcgc attgacctga accgttgctg cttgataggt tggaaaattt
    11581 gaaacatttc ccttaccatc aacgatctgc ccatttttga tcgagtaccc cgtgaatgga
    11641 atatcatttg ctaactgtat accgattgaa aaagtactca tacctcctcc ggcaggaagc
    11701 cctccccatg ttgagggtgt aaaagaataa cttttatccg cattgggtgt aactgaatcg
    11761 atcgtatttc cagcggtagc cacccccata tagatacttt ttgggaatgt gatagtagta
    11821 ccatttactg tggagccaat aaacagatta tggatatctg gacggttatc aataaaagcg
    11881 attgctttgg ttacgccttg taacgcagtt ttatccgcac tcatcgatcc gttaaccgca
    11941 acaatgactc catctttggc atatatcact gtatatccat ctggtatggt atgtccgttg
    12001 aaattcgcag tggccgcaac agtactaaat gtctggcttc tacctgtttc tgaataagct
    12061 ttctcccctg ctgcttttgc tgctgtgatt tctttttctg tcggatcaat cagttgagtc
    12121 gaggatgtgg ttgaggttgt ctcgttgttg ctagactgat tggtgctttc tatggactgt
    12181 atttcagaat agggtggact atttgtctcc tctgtcgttt ggttagcaaa atttgacgtt
    12241 tctgtataaa cgtttacata aatacttgat aagctcccta agaaagtaaa aatcaagatg
    12301 atcgaaatca taatgggatg taagtatttt cttttagata cagctttgag tctagaaaca
    12361 aaatgttttt gacatatacg ttggatttta ttttgagttt tcttaatcat tttcatccct
    12421 cctctcaata aa
//
LOCUS       DADQDV010000080        12163 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.083, whole genome shotgun sequence.
ACCESSION   DADQDV010000080 DADQDV010000000
VERSION     DADQDV010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12163)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12163)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12163
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.083"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            158..730
                     /locus_tag="J8S10_002471"
     CDS             158..730
                     /locus_tag="J8S10_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003706982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HAZ9631038.1"
                     /translation="MTENKATQERTPQERLQEEQEHKEHVHHTKINAAAIADHLLGNM
                     HTLHVKLHQYHWYVKGANFFTLHEKFEELYNENEKWFDKLAERLITSGHKPASTTVEF
                     EKYSMLSEDAVNKYAKAEDMVENIIEDFRSTRDLTIRAIRLAQDEGDDALEDTLIAFK
                     NDLDKNIWMLQAFIGKEALEDDDALDEDED"
     gene            962..1579
                     /locus_tag="J8S10_002472"
     CDS             962..1579
                     /locus_tag="J8S10_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006845390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAZ9631039.1"
                     /translation="MNYIAEKAHTKQYQKGEFLFRSQEKEDTLYIINRGKIRIYRLAD
                     SGKEQLVRILNPGDFTGEWTLFNPDAVHEEYAEATRDTVVCMIQQKDVQDFLEQYPAI
                     SLKLLAEMSKRLESSERQTTQVAVESVITRLVLFLAENVEPEMGNSPTITLPMAKKDI
                     ASYLGTTPETISRKFGELEDEGLIQQLSGKRIKIQDLDDLLLYSE"
     gene            1807..2145
                     /locus_tag="J8S10_002473"
     CDS             1807..2145
                     /locus_tag="J8S10_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003102891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631040.1"
                     /translation="MHCFWVIVAITLSAAGAFFVVPFTKNTIGGEAKTSNVVEADRLA
                     MEKEEEVVKGAGVIGHGKVAYYEASDQGDKSVFTVWFPWSLAGILFSITMTRMTRKIE
                     EMEQIEWDSY"
     gene            2130..2984
                     /locus_tag="J8S10_002474"
     CDS             2130..2984
                     /locus_tag="J8S10_002474"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003125438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HAZ9631041.1"
                     /translation="MGFVLGVLNPHVVEIGSVVIHWYGVIIAAGILAALQLSTKEAKK
                     KGLEEDTIIDMALWAIPIGLLGARLYYVLFELGYYLQNPGQILAIWNGGIAIYGGLIA
                     GGGTLYWYAKKKGTSLALVLDILAPNVLLAQSIGRWGNFMNQEAHGGPVTRQFLENLY
                     LPEFIIEQMNMNGTYYHPTFLYESLWSLLGFVLIVTIRNRKQLLRQGEVALSYVLWYS
                     VGRFFIEGMRTDSLWIGEWIRVSQALSLALFIGAIVVWFIRRQDYPPISYYSDGNKGQ
                     KKTIKMVN"
     gene            3131..3364
                     /locus_tag="J8S10_002475"
     CDS             3131..3364
                     /locus_tag="J8S10_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HAZ9631042.1"
                     /translation="MEKAILQLETLSCPSCMQKIEGAVKSVNGIDKDSIKVLFNSSKV
                     KTNFDSAVTSIEEIQKAIENVGYPVLKAKVKAV"
     gene            3562..5466
                     /locus_tag="J8S10_002476"
     CDS             3562..5466
                     /locus_tag="J8S10_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HAZ9631043.1"
                     /translation="MQQYILSKKNVITVISGLLIVLGFFSHFVLENVGLSEWSLIIAS
                     VFGITPIAIQAFQAMKVKVISIDVLVSIAAIGALFIQNYEESAIVTFLFLFGHYLEQR
                     TLNQTRSAIKELTEMAPESALKQMDNGEFEEVEVDDIDEGDILLVKTGAKVPVDGIVL
                     TGEGHINEASITGEAIPVNKLADAEVFAGTILENGTIQIRADRVGEDTTFGKIIELVE
                     EAQDSKSEAERFIDRFSKYYTPAVLVLAIVVWAFSQNIELAITILVLGCPGALVIGVP
                     VSNVAGIGNGARNGVLLKGSEVIQDFSNVDTIVFDKTGTLTVGNPTVAATELYEKDPA
                     ETLGYLASVERESDHPLAKAVLNQIGETNFYPVEGTEVVKGGGIVSSVAGHRVAVGNV
                     ALMEKENVTLSKKVQKDVKRFEQQGNSLVLTAVDGELKVLMGIRDQVRPGVKANLQEL
                     KDLGVKNLVVLSGDNQGTVDVVAGELGLTEAHGYMLPEDKSAYIGKLQQRGQIVAFVG
                     DGVNDSPSLALADIGIAMGSGTDVAIETSDVVLMNSNFSNLPHALGLVKATANNMKQN
                     IVISIGVVLVLLTSVFFSEWMNMSIGMLVHEGSILVVIFNGMRLMKYKLKGRKEQKEV
                     SAPAEKVKIS"
     gene            5776..6138
                     /locus_tag="J8S10_002477"
     CDS             5776..6138
                     /locus_tag="J8S10_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAZ9631044.1"
                     /translation="MEKVCQVTIVHKEKVNVIKKKLDQKDFSNLLVLGKCFSDSSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVFLKLSENLSMKS"
     gene            6155..6766
                     /locus_tag="J8S10_002478"
     CDS             6155..6766
                     /locus_tag="J8S10_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HAZ9631045.1"
                     /translation="MLQSIFSAIAVYISTSIDYLFILLIIFSQSHTKKGIRHIFWGQY
                     LGTGILVAVSLFAAYVLNFIPQDWIIGLLGLIPIFLGIRVAFVGEEEEEEEEVVEKLE
                     SRGTNRLFWTVALITIASGGDNLGIYIPYFTSLAFSEIIIALIVFAISVAVLCYISYK
                     LAKISFVSETLEKYERIIVPIMFIALGIFIMIENGTIQTLLGF"
     gene            complement(6868..7776)
                     /locus_tag="J8S10_002479"
     CDS             complement(6868..7776)
                     /locus_tag="J8S10_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HAZ9631046.1"
                     /translation="MSKSDKDHNHSNQNQPKKNIKIAFFINLIFSISEFFFGFLFNSV
                     SIMSDAVHDLGDSISIGFAWFFQGYSEKKQDERFTFGYNRFSLLGALITGVVLISGSF
                     FMIYRSVPRLIDPQPVNYSGMFWLSLVAIALNGYAAWILSKGTSKNESMLNLHMLEDV
                     LGWIGVLIVSILMNFTEAYRLDPILSILIALYILYKTVPEFFTTMKILLNGSPENVNV
                     KSLADSIKNVPAVKDLSHFHIWSLDGEENALIITVLIDPSDIDKAREIKEEIAEVAHK
                     SSVENHITIEITTSKEELEKGYSHNT"
     gene            complement(7818..8132)
                     /locus_tag="J8S10_002480"
     CDS             complement(7818..8132)
                     /locus_tag="J8S10_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HAZ9631047.1"
                     /translation="MDIKTTSPIDKGSILSISKLFKVISDPTRLSVLFLLQKKECSVG
                     NIAISLDMEQSAISHQLKTLKDARLVKSRREGKSMLYSLDDLHVFSILEQVLTHVNEL
                     EK"
     gene            8431..10362
                     /locus_tag="J8S10_002481"
     CDS             8431..10362
                     /locus_tag="J8S10_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HAZ9631048.1"
                     /translation="METIQEQQSQEKHNHNHNHDHDHDHGKMPVVLYFVGLALAVIAL
                     FLNEDYQLVQNVLFSIATISAGYHVILLEGLGETIENSKAQKKFIPNSHILMGLAAIG
                     ASLMGNFWEGTLLILIFSGAHFLEDYAEGRSKREITKLLEMNPTTARLILPDGSTKNV
                     DVSELKVGDQLQVLNGDQVPIDGVILSGSTSIDESSITGESIPKEKSKGDGVFGSTIN
                     GTGTFTMKVTKENKDTVFSKILQLVNQNQDNQTKAASIIQKFEPKYVTVVLIAIPLFM
                     LLAPFLLDWTWSQSVYRGLVLLVAASPCALAAATVSATLSTTSNLAKKGVLSKGSSYL
                     SQLADIKAIAFDKTGTLTKGKPEVTNYYFADSVNEENMIDIVVALEKESNHPLADAIL
                     RKFEQKNKLTIEVENQIGKGLTGDYKGRNYRIGKPTSFDDVSDEYSRLNNEWASEGKT
                     VVYVAVDEEVIGLIALMDVPSEYAKETIEYFRKQGIHTTLITGDSEMTGKAVAKQLGI
                     DEVIANVMPEDKSRIIDEQKEKYGVTAMVGDGVNDAPALVNADVGIAMGDGTDVAVEV
                     SDLVLMQNNLSKLVQSHNISSKMNRVIWQNIIFSMAVVAFLIVVSFLGLTDIAISVII
                     HEGSTLVVILNGLRLLKAV"
     gene            10655..11206
                     /locus_tag="J8S10_002482"
     CDS             10655..11206
                     /locus_tag="J8S10_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAZ9631049.1"
                     /translation="MGYNVQPLRSQQEINDFLFCLRRNKNAERDVFLFLIGINSGLRM
                     SDIVKLKKKDVITSKNPRIVEQKTGKTRILYLSSLQDLIHGYTAPLDPEAYLFPSTKG
                     GHLEVNTVYQMFQKVAKLLGRDDIGTHTLRKTFGYHYYKKTKDVATLMEIFGHSSEKI
                     TKRYIGINEDEISETLLNFRLGF"
     gene            11519..12061
                     /locus_tag="J8S10_002483"
     CDS             11519..12061
                     /locus_tag="J8S10_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631050.1"
                     /translation="MSIKETTQITRQLNAIYKAAHLLQEHFVDKKVSFVGEVSTVAII
                     FSTTNFMHLCGIDYRRGTHLFFQDALDRKINLQDIQIKTDGTTFQKLQVIGSLDLLLG
                     KHISIVGRGVYSSLRYDAAIRTRKKILALSLKQNGLIYIPISLLNLSSKEIGPGQKVT
                     GIFSEDLTSGELKMIMEVID"
BASE COUNT         3952 a         2034 c         2555 g         3622 t
ORIGIN      
        1 aatttaatag agaagcctgg cgtctattaa gaaataattt tcttgatgag cgtcaatttt
       61 tttaacggaa atctatccta tactaaattc agtaaagaaa aaggaggaat caaagaaagc
      121 tattttaaac aaaccaaaat tataggagga ataaatcatg actgaaaata aagctactca
      181 agaaagaaca ccccaagaaa gattgcaaga agaacaagaa cacaaggaac atgttcatca
      241 tacgaaaatt aatgcagcgg ccattgcgga tcatctttta ggcaacatgc atacattaca
      301 tgtgaaactg caccaatatc actggtatgt aaaaggagcc aatttcttta cgttgcatga
      361 aaaatttgaa gagttgtata acgaaaatga aaaatggttc gacaaacttg cggagcgtct
      421 aattacttct gggcataaac ctgcttcgac aacggttgaa tttgaaaaat attcgatgct
      481 ttcggaagat gcagttaata aatacgctaa agcagaagac atggttgaaa atattatcga
      541 ggacttcaga agcactcgtg acctaactat tcgcgcgatt cgtttagctc aagacgaggg
      601 tgacgatgct ttagaagata cattgattgc ttttaaaaat gacttagaca agaacatttg
      661 gatgctgcaa gcgttcattg gtaaagaagc attagaagat gatgacgctc ttgatgagga
      721 tgaagattaa ggtaaaagta gaagctgatt tagggattgg aattctttcc agtccttttt
      781 ccattttctt gatgtgcatc aatttttttg tagtaagaga cttatataat aaaagcagcg
      841 aatataaaca aaataaataa agggggagaa tgaattgact aaacataccc atcatgaaat
      901 tggcgaccac gcagcctgta tccgcttggt tccaatattc aatcacttag aggatagcgc
      961 gatgaattac attgctgaaa aagcccacac gaaacagtat caaaaaggag agtttctgtt
     1021 tcgttcacaa gaaaaagagg atactttata tattatcaat cgtgggaaaa tccgtattta
     1081 tcgattggca gactctggca aagagcagct agtgcggatc ttgaaccctg gtgatttcac
     1141 cggagaatgg accttgttca acccggatgc agtacacgag gaatatgccg aagcaacccg
     1201 agataccgtt gtctgtatga ttcagcaaaa agatgtccaa gattttctgg aacaataccc
     1261 agctatttct ttaaaactat tggcggaaat gtctaaacgg ttagaaagtt cagaacgtca
     1321 aacgacacaa gtagccgtgg agagtgtcat tacccgttta gttttgtttt tggcagaaaa
     1381 tgtggaacct gaaatgggca actctcccac catcaccctg ccgatggcaa aaaaggacat
     1441 tgcttcctat ttaggaacga cacctgagac catcagtcgc aaatttggag aattggagga
     1501 cgaaggattg attcaacagc tgtctgggaa aaggatcaag attcaggatt tagatgattt
     1561 attgctttac agcgaataat cggacacact tttttctaca cgttggtgtt ctgtcgctct
     1621 tcattaacaa cgggacagaa ctcagtgctt ttgcttccat ctgtccgttt ttggcttttt
     1681 taagacagaa cgaccttcat tcattggaaa aataaaagca caaacatgat aaccctcaag
     1741 tttttttgtt ttatttttct ttaagatagg gttgtcgaac aaaacgtaaa aataagtagg
     1801 gtgaatgtgc attgtttttg ggtgatagtt gccatcacgt tgtcagcagc gggggcattc
     1861 tttgtcgtcc ctttcaccaa gaacacgatt ggcggcgaag caaaaacgtc taacgttgtt
     1921 gaggcagata ggttagctat ggaaaaagaa gaggaagttg taaaaggagc cggcgtaatc
     1981 ggacacggaa aagtggcgta ttacgaagcg agtgaccagg gagataaaag tgtattcact
     2041 gtttggtttc catggagctt agccggaatc ttgttcagca tcaccatgac tagaatgacg
     2101 cgaaaaattg aagaaatgga gcaaatagaa tgggattcgt attaggcgtt ttgaatcccc
     2161 atgtggtgga gattggttct gttgtgattc attggtatgg agtcattatt gcagcgggca
     2221 tattagcggc tctccagttg agcaccaagg aagcaaagaa aaaaggactg gaagaggata
     2281 ccattatcga tatggcctta tgggcaattc cgattggact cctcggcgct cggctttatt
     2341 atgtgttatt tgaacttggt tattatctgc aaaatccagg acaaatcctt gcgatttgga
     2401 atggcggcat tgcgatttat gggggattga ttgcaggagg gggtacgcta tattggtatg
     2461 caaagaaaaa aggtacttct ttggcactcg ttcttgatat tttagcgccc aatgtattgt
     2521 tagcccagtc cattggtcgt tggggcaatt ttatgaatca ggaagctcat ggtgggccgg
     2581 ttactcgtca attcttggaa aatctttatt tacctgaatt tatcattgaa caaatgaata
     2641 tgaatggtac ctactaccat ccgacttttt tatacgagtc attgtggagt ttgttgggct
     2701 ttgtcctcat cgtcactata cggaaccgaa aacagctttt gcgtcaagga gaagtcgctt
     2761 tgagttacgt tttgtggtac tcagtgggtc ggttcttcat tgaaggtatg cgaacggaca
     2821 gtttatggat tggcgagtgg atccgcgttt cgcaagcctt gtctctggcc ctgtttattg
     2881 gcgcgattgt agtatggttt atacgcagac aagattatcc accaatttct tattattctg
     2941 atggcaataa ggggcagaaa aagactatta agatggtgaa ttgagcaaaa agataaaaag
     3001 aagtgcaaaa cttgatatgc gtcaattttc gtttgctaaa agtgagctat actacagttg
     3061 taaagaggaa aaggcagtgt tcattaatct gctgccgata aaataaaaac acataaagga
     3121 gataggaatt atggaaaaag ctatattgca attagaaacg ttgtcttgtc caagttgtat
     3181 gcaaaaaatt gaaggtgccg tgaaatcagt taacggtatt gataaagaca gcattaaagt
     3241 attattcaac tccagcaaag tcaaaaccaa ttttgattca gctgtcactt cgattgaaga
     3301 gattcaaaaa gctatcgaaa acgtaggcta tccggttctt aaagcaaaag tcaaggccgt
     3361 ttaacagatt aaatgaacta ggcaattctg gaagaaaagc tatttttcca ggattgcttt
     3421 ttttgttgca atccgattcg aggtgcttag aaacgataaa agagaacttt ctaaacttga
     3481 tgtcagtcaa ttaattactt aggcaattat cttatactgt gtttatcaat aaaagagaaa
     3541 ttaaatttgg agggaaaaag catgcaacaa tatatattaa gcaagaaaaa tgttatcacc
     3601 gtcatcagtg gattgttaat cgtactcggt ttcttcagtc actttgtttt agaaaacgta
     3661 ggactttcag agtggtcttt gatcatcgcc tctgtctttg ggattacgcc aattgccatt
     3721 caagcgtttc aagcaatgaa agtcaaagtc atcagtattg atgtcttagt cagtattgca
     3781 gcgattggtg cgctttttat tcaaaattat gaagaatcgg ctattgtcac gttcttattc
     3841 ttattcggac actacttgga acaacgaaca ttgaaccaaa cgcgatctgc tatcaaagaa
     3901 ttgactgaaa tggcacccga aagcgccttg aaacaaatgg ataatggcga atttgaagaa
     3961 gtagaagtgg atgatataga tgaaggggat atcttgctcg ttaaaacggg tgcgaaagtt
     4021 ccagtagatg gcatagtcct tacgggtgaa gggcatatca atgaagctag cattacaggt
     4081 gaagctattc cggtcaacaa gctagctgat gcagaagttt ttgcaggaac cattttagaa
     4141 aacggaacga ttcaaatcag agctgaccga gttggtgagg acaccacatt tggaaaaatt
     4201 attgaactcg tggaagaagc acaagattct aaatccgaag cggaacggtt cattgatcgc
     4261 ttttctaaat actacacacc agctgtcttg gttctggcaa ttgttgtatg ggcgttcagt
     4321 caaaatattg agttagcaat caccatcttg gttctaggtt gcccaggcgc attagttatc
     4381 ggagtgcctg tctcaaacgt tgccggtatt gggaatggtg ctcgtaacgg tgttctttta
     4441 aaagggagtg aagtcattca agacttcagt aatgtggata caattgtatt tgataagaca
     4501 ggtactttaa ctgtcggaaa cccaaccgtt gcagcgactg aactgtatga aaaagatcct
     4561 gctgaaacgc ttggctatct ggccagtgtg gaacgggaat cagatcatcc attagcaaaa
     4621 gcggtcttaa atcaaattgg agaaacaaac ttttatcctg ttgaaggaac tgaagttgtg
     4681 aaaggcggcg gaatcgtttc aagtgtagct ggacatagag tggctgttgg gaatgtggcc
     4741 ttgatggaaa aagaaaatgt cactctcagc aaaaaagtgc aaaaagatgt caaacggttt
     4801 gaacaacaag ggaactctct cgttttgaca gcggtcgacg gtgaattaaa agtactgatg
     4861 ggcattcgcg atcaagtccg tccgggtgtg aaagctaatt tgcaggaatt aaaagacttg
     4921 ggcgtgaaaa atctagtcgt tctttcagga gataaccaag gaaccgttga tgtggtcgcc
     4981 ggcgaacttg gtttgaccga agctcacggc tacatgttgc cggaagacaa atcggcttat
     5041 atcggaaaac ttcaacaacg tggtcaaatt gtagcctttg ttggagatgg cgttaacgat
     5101 agtccgtcct tagctttagc agacattgga atcgcaatgg gaagcggaac ggacgtagcg
     5161 attgaaacat ccgatgtcgt tttaatgaac tcgaacttca gcaacttgcc tcacgcatta
     5221 ggattagtaa aagccaccgc aaataatatg aaacaaaata tcgtgatttc aattggagta
     5281 gtgttggtct tgttgaccag cgtcttcttc agcgaatgga tgaatatgtc tatcggaatg
     5341 ttggttcatg aaggtagtat cttggtggta attttcaatg gcatgagatt aatgaagtat
     5401 aagttgaaag gtcgaaaaga acaaaaagaa gtatcagcac ctgcagagaa agtaaaaata
     5461 tcttaagaat aaattagaag aggctgagac aatagtccat ccttgaaatg acaaaagcgg
     5521 aaactcagat ttttaaatct gggattttcc gcttttttga gttcttgaaa aaaaataaga
     5581 gtatagagta tgttctttat aaaattaatt ttcgtgtaaa tgattaaaaa atttaataat
     5641 aaaatttaaa ttcctattaa gttgtaacac atgaaattgc ttataatagt gtattgaaat
     5701 taaggtagat tgacaaacga gtgatcaaat agatatacta ccttcaaacg accgtttgaa
     5761 tgtgaggtga gatgaatgga aaaagtttgc caagtgacta tcgtacataa agaaaaagta
     5821 aatgtaataa aaaaaaaatt ggatcaaaaa gatttttcaa acttacttgt gttagggaaa
     5881 tgtttcagcg attcttctag gattaaaatt ttctatgctt tagaaaccta taaggaaatg
     5941 tgtgtctgtg atttagcaga aatacttact gctagtgtcg ctacaacgtc acaccattta
     6001 cgttttttaa aaaaacatgg aatggcaaaa tcacgtcaag atggaaaagt agtttattat
     6061 tctttagcga atgaagacat cctttccgct attcgtgttt ttttaaagtt atcagaaaat
     6121 ctatctatga aatcttagtt tggaggaagt tattttgtta caaagtattt tttcagctat
     6181 cgctgtttat atttctacca gtattgatta tttgtttatc ttgctgatta tcttttctca
     6241 aagccacaca aaaaaaggta ttcgtcacat tttttggggt caatatcttg gaacaggtat
     6301 tttggtagcc gtaagtttgt ttgctgctta tgtgctaaat tttattccgc aagattggat
     6361 cattggtctt ctcggtctaa ttccgatttt cttaggaatc agagtcgctt ttgttggcga
     6421 agaggaggaa gaagaagagg aagtcgttga aaaactcgaa tctagaggaa ctaatcgctt
     6481 attctggaca gttgccttaa taacgattgc ttctggaggc gataatttag gtatttatat
     6541 tccatacttt acctcgttag ctttttcaga aatcattatt gctttaatcg tattcgctat
     6601 ctctgttgcg gttctctgct atatcagtta caaattagcc aagatttctt ttgtttccga
     6661 aacgttagaa aaatacgaac gaatcattgt ccctataatg tttattgcgt taggaatttt
     6721 tattatgata gagaacggga cgatacaaac gctactaggt ttttaaaaat cataatcacg
     6781 aaagataaaa agagaggcag cgactaatca aaatcgctgc cttttttgct tttcaaataa
     6841 tgaagtattt tttagcgtag aactatctta cgtgttgtgg gagtatccct tttcaagctc
     6901 ttctttgctt gtagttattt ctattgtgat atgattctct acgcttgatt tgtgtgcgac
     6961 ttctgcaatt tcttctttta tttccctagc cttgtctatg tctgaagggt ctataagaac
     7021 cgtgatgata agggcgtttt cttccccgtc cagtgaccaa atgtgaaaat gtgagaggtc
     7081 ttttacagca ggaacatttt taatggagtc cgccaagctc tttacgttta cattttcagg
     7141 cgaaccattc aataaaattt tcattgtggt gaaaaattca ggaacggttt tgtagaggat
     7201 ataaagtgca atcaaaatcg ataagatagg atccagacga tatgcctcgg taaagttcat
     7261 tagaatactc acaatcaaga ctccaatcca ccctaatacg tcttccagca tatggaggtt
     7321 caacatgctc tcgtttttgg atgtgccttt gcttaaaatc cacgcagcat atccattcaa
     7381 tgcaatagct acgagagaaa gccagaacat gccactataa tttacgggtt gtgggtcaat
     7441 caaacgtggc acactacgat agatcataaa aaacgagcca ctaattagca caacgccagt
     7501 tatcagcgcg cccagtaaag aaaagcggtt atagccaaaa gtgaaccgtt catcttgttt
     7561 tttctctgaa taaccttgaa aaaaccaagc gaatccaatt gaaatagagt cccctaaatc
     7621 atgaactgcg tcggacataa tggacacact attgaaaaga aagccaaaga aaaattcgct
     7681 tatagagaaa ataagattta tgaagaaagc aattttaata ttctttttcg gttgattctg
     7741 attcgagtga ttatggtctt tatctgattt tgacatttaa aaacctccta agtttgtatg
     7801 ctacatacta attggtttta tttttctaat tcattaacat gagttaagac ttgttcgaga
     7861 atactaaaaa catgaaggtc atctaaactg taaagcatac tttttccttc tcttcttgat
     7921 ttcactaagc gtgcgtcttt caacgttttt aattgatgag aaatagcgga ctgttccatg
     7981 tccagagaaa tagcgatatt tccaacacta cactcttttt tctgtaaaag aaagagaacc
     8041 gacaatcgtg taggatcact aatcacctta aatagtttgc ttattgacag aatagatcct
     8101 ttatcgattg gagaagttgt ttttatatcc atagtgtttt tattcctttc atatgacctt
     8161 ccgttcatat ctatattacc atatgagcga aacaatgcta atcttttgtt tataaaagag
     8221 aagtggcgtt ctctttatct tgacaaaatg tatatagcga tataaaatga gtatacaaac
     8281 atatgattaa ttagtcatat gtaaggtgga ttcattacga tttacttttg gaataaacga
     8341 aaggagtcag aaatagcaga aatttatgtg attcaagaag taaatgatgg aaaacaaagg
     8401 aattataaat tatataggga ggcaatagaa gtggaaacta tccaagaaca acagtctcaa
     8461 gaaaagcata atcataatca caaccacgat cacgaccatg atcatgggaa aatgccagtc
     8521 gttttgtact ttgttggttt agcattagca gtgattgctc tatttttgaa tgaagattat
     8581 cagttggtac aaaatgtttt gttctcaatc gctacaatca gtgccgggta tcacgttatt
     8641 cttcttgaag gccttggaga aacaattgag aattcaaaag cacaaaaaaa gttcatacct
     8701 aattctcata ttttaatggg attagcggca attggagctt ctttgatggg gaatttttgg
     8761 gaaggaacat tattgattct tattttttct ggcgcacatt ttttggaaga ttatgcagaa
     8821 ggaagaagca aacgagaaat aacgaaatta ctcgaaatga atccaacgac tgcccggtta
     8881 atcctgcctg atggtagtac aaaaaatgtg gatgtcagtg aattaaaagt gggagatcaa
     8941 cttcaagtgt tgaatggcga tcaagtacct attgatggcg tcattttgtc tggatctaca
     9001 tccattgatg agtcgtctat tactggagaa agtatcccga aagagaaatc caaaggagat
     9061 ggcgtcttcg ggagtacaat caatggaaca ggtaccttca cgatgaaagt caccaaagaa
     9121 aacaaagata cagtattttc aaaaatttta caattagtga atcagaacca agataaccaa
     9181 acaaaagctg cgagtattat ccaaaaattt gaaccgaaat atgtcacagt tgttttaatt
     9241 gccattcctc tattcatgtt attggctcct tttctacttg attggacatg gtcacaaagt
     9301 gtctatagag gattggtcct tttagttgca gcttcaccgt gtgctttagc agcagctact
     9361 gtctcggcaa cgctatcgac gacttctaat ttagccaaaa aaggagtcct ttcaaaaggt
     9421 agttcttacc tgtctcaatt agccgatatt aaagcaattg catttgataa gacgggcacc
     9481 ttgaccaaag gaaaacctga agtaaccaat tattattttg ctgattccgt gaacgaagaa
     9541 aacatgattg atatcgtagt agctcttgaa aaagaatcca atcacccctt agcagatgct
     9601 attctaagaa agtttgagca aaaaaacaaa ctaactattg aagtagaaaa ccaaattggt
     9661 aaaggattga cgggagatta caaagggaga aattatcgta taggaaaacc gacttcgttt
     9721 gatgatgttt cagatgaata tagtcgttta aataatgaat gggcgtcaga aggtaagaca
     9781 gtcgtatacg tagcagtaga tgaagaggtt ataggcctta ttgcccttat ggacgttccg
     9841 agtgaatatg ctaaagaaac cattgaatat tttaggaaac aaggtataca caccacatta
     9901 attactggtg actcagaaat gacgggaaaa gcggttgcta aacaattagg aatagatgaa
     9961 gtgattgcga atgtcatgcc ggaagacaaa tccagaatta tagacgaaca aaaagaaaaa
    10021 tacggcgtga ccgccatggt tggagacggt gtaaatgatg ctcctgctct tgttaatgca
    10081 gatgtgggaa tcgctatggg agatgggact gatgtggcag tagaggtatc tgatttagtt
    10141 ttaatgcaaa acaatttatc taaattggta caatctcata atatttcttc gaaaatgaac
    10201 cgtgttattt ggcagaatat tattttttca atggccgttg ttgctttttt aattgtcgtt
    10261 agtttcttag gcttaacgga tattgcaatc agtgtcatta ttcatgaagg aagtactttg
    10321 gttgttattt tgaatggact tcgattgcta aaggcagtct aaagaatgat tgcacaactt
    10381 caaattaatc gagtaataga gataattaag gattacacta cattttttat ctctattact
    10441 tgtttatatt tatctagatg ttcaaagtca aaatgatata tcaaccatac tcttgtggcg
    10501 cgggttgaat ataagataca tgaaattgga taaaatcatg tatcaagaat cctatcctta
    10561 tagggttctt tttttttact ccccctaaac acacgatttc gtgttgtaat aactataatc
    10621 atgtattcga acagactaaa aaggagggat tgtcatgggc tataatgttc agccactacg
    10681 gtcgcaacag gagattaatg attttttatt ttgcctgcga cggaataaaa atgcggaacg
    10741 tgacgttttc ttgtttctaa ttggaattaa cagcggtctg cgcatgtccg acatcgttaa
    10801 actcaagaaa aaagacgtga ttacctcaaa aaacccgcgc atcgtggagc aaaagacagg
    10861 gaaaacacgc attttatact taagcagctt acaggacttg attcacggct ataccgcacc
    10921 cttagatccg gaggcttact tgtttcccag tactaagggc ggccatttag aagtcaatac
    10981 ggtctaccag atgtttcaaa aggtcgcgaa gctgttagga agggacgata tcggcaccca
    11041 caccctacga aaaacctttg gttaccacta ttacaagaaa accaaagacg tggccacctt
    11101 aatggaaatc tttggtcaca gcagcgagaa gattaccaaa cgctacatcg gaattaatga
    11161 agatgaaatc agtgaaacgt tattaaattt tcggttaggt ttttgattgt attatataat
    11221 agataagcac agtaagacgg ttataatcac ccacagtatt ggacaaatca accttttttt
    11281 ggtatattat atatacaaat gagagcaggc tcatagtcaa cttgatataa atccggaaca
    11341 taagggtccg gcgggtggcg agcaccaaaa ctaaactcga tacaaatccg gaacgtaagg
    11401 gtccggcggg tggcaagcac caaaactaaa cctgtacaaa aggctgctct tttgagcagc
    11461 tttttttatt gggaaaaagg agcattcttc gcacgcggca aaaaaagaat acaaacgcat
    11521 gtctataaaa gagacaaccc aaattaccag acagttaaac gcgatttata aggctgctca
    11581 tctcttacaa gaacattttg tagataaaaa agtatccttt gtcggagaag tctcaacggt
    11641 agcgattatt ttttcgacaa ctaattttat gcacctctgt ggcattgatt atcgcagagg
    11701 cacacacttg ttttttcaag atgccttaga caggaaaata aatttacagg atattcaaat
    11761 caaaacggat gggacgacct ttcagaaatt acaagtaata ggtagccttg atttattatt
    11821 ggggaagcat atttctattg ttggcagagg tgtttactct tctcttcgct atgatgcagc
    11881 tattcgaaca aggaaaaaaa tattggctct gtctttgaaa caaaacggat taatctatat
    11941 ccctatctct ttgttaaacc tatcatcaaa ggaaattgga cctggacaaa aagttactgg
    12001 catttttagc gaggatttaa catccgggga acttaaaatg attatggaag tcatcgatta
    12061 atcattaata gtgatatgcg acgtcatttt gaagtaatta ttctattttg ggttataaaa
    12121 taaagcattt taagacgatt tcaaatcatt catgtgggtt att
//
LOCUS       DADQDV010000081        12021 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.084, whole genome shotgun sequence.
ACCESSION   DADQDV010000081 DADQDV010000000
VERSION     DADQDV010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12021
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.084"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            560..1531
                     /locus_tag="J8S10_002484"
     CDS             560..1531
                     /locus_tag="J8S10_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HAZ9631051.1"
                     /translation="MEGTVLRIEQGSLHDGAGLRTVVYLKGCPLRCAWCSIPESQSKQ
                     IEKGFGQTMTAEEVMDEIEKDAVFYFHSDGGVTISGGEALVQADFAKEILQKSKYIGI
                     NTVLETSFCGAYNEIQKVAPYVDTLFVDVKMFTSKLHKQWTGLDNQQILKNIRRFLIE
                     YPNCEVRIRVPVVPGINMNLTELLTIACFVADLDRFVPLELLPYHCYGMHGYQALGLE
                     YPLADTPAPSPKEMFALADQLARTVPHLLVTALTKTFIYLLNPSFILWINERHSLAAA
                     SSRIELLLKSVSVFLRCFFEVNLSNEHWLNRYIFTVCRLSCDRCYDF"
     gene            complement(1609..1845)
                     /locus_tag="J8S10_002485"
     CDS             complement(1609..1845)
                     /locus_tag="J8S10_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAZ9631052.1"
                     /translation="MTTHLSARVIKEFVIQGGALDGSGDEAVSSYEGFFADEVHRGLY
                     HFNGALALGDHGPHTNGNQFFIVQNTKAQADLLM"
     gene            complement(1814..1945)
                     /locus_tag="J8S10_002486"
     CDS             complement(1814..1945)
                     /locus_tag="J8S10_002486"
                     /inference="COORDINATES: protein motif:HMM:NF012387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAZ9631053.1"
                     /translation="MLVTDAGEIRLRLFPDQAPLAVANWRSLAEQGVYDNTPFGSCH"
     gene            complement(2021..2404)
                     /locus_tag="J8S10_002487"
     CDS             complement(2021..2404)
                     /locus_tag="J8S10_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HAZ9631054.1"
                     /translation="MSNLWDYNQEAPIHYLIARHWDALKIEAVCRSLLAAVPKQQLEN
                     FLVADSLQREKVQAYFAAFKDQPLEYLHAQFHLFYQVAAPDDYNDLRGQLQLTFQADE
                     TAYTVLLGMARLGDQAKVEWRIFDI"
     gene            complement(2437..3222)
                     /locus_tag="J8S10_002488"
     CDS             complement(2437..3222)
                     /locus_tag="J8S10_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol phosphate phosphatase"
                     /protein_id="HAZ9631055.1"
                     /translation="MQYYDQHLHTYFSFDSEEKFENYLAYQPEFFVSTDHFDLNNPST
                     GKDDIPDYPAYINKLDSLKETYSTKFLRGIEIGVVPGQEERIVDYLAQHPYDLKLVSI
                     HQNGRFDYMDDVVLTKDPIQTTKEYFDQMLQVLTDFPEGDILTHFDYGLRRFTFTAEE
                     FAEHFEAQLLTIFKKVVERELAMELNAKSFLKYGNEDLYRYAVPLYQSVGGKLFTLGS
                     DAHVAEDYQLGFKKMSQLLADCQVEKLLVIQGKERRLTPLPIL"
     gene            3400..4500
                     /locus_tag="J8S10_002489"
     CDS             3400..4500
                     /locus_tag="J8S10_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAZ9631056.1"
                     /translation="MKMNEKIRNMTIGLFCAATVSILLTGCGSGEATKQSAAADDSLD
                     TIIEKAKEEGEIASLGMPDTWANWVGTWNDLEKEYGLSHVDTDMSSAEELAKFESEGK
                     NGTADIGDVGISFGPLAESKELTLPYKTNYWEEIPDWAKDDDGDWLLSYTGTISFITD
                     KENVKQAPTSWKELQEGDYQVSVGDVTIANQAQFAVLAAAIANGGDEKDIQPGLNYYK
                     KMAEKGRLSTVDASVANLEKGEIDVAVVWDFNGLNYRDQIDSERFEVTVPTDGSIISG
                     YTTLINKNAPHPNAAKLAREYILSDEGQINLAKGYARPIRKVELPKEVAEKLLPEDAY
                     EAAVPVEDNEAWNKTSVELPELWQAEVLTYAK"
     gene            4490..5314
                     /locus_tag="J8S10_002490"
     CDS             4490..5314
                     /locus_tag="J8S10_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphatase"
                     /protein_id="HAZ9631057.1"
                     /translation="MQSRLDKLIVVILDGCRYDTAVAQLGFMNHLVEHQQASLLKVKS
                     ELPSNSRPLYEVLMTGVPAYENGIYSNYHAQRSKEWSLFELVKEAGGKTGAAAYHWYS
                     ELYNQAPYNRLVDRIQHQEERLIQHGIFYSEDTYPDSHLFADAHYLVNQYQPDFLVVH
                     SMNIDDVGHKFTADSHEYAAAVNQADRLLAIYLPEWLQKGYQVVVTADHGMDAHGLHG
                     GSLAAHREVPFYLISNKRQKLKEQTVPQLLAAPLFCWLLGIAPSEKMQDIQELMRG"
     gene            5320..6126
                     /locus_tag="J8S10_002491"
     CDS             5320..6126
                     /locus_tag="J8S10_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010757330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAZ9631058.1"
                     /translation="MKKRLVLVPASFIFCAFLLLPLLFMVLCSLHSDLTNQWTLANYS
                     DIFSNKYYTQAFVNSVLIAVSSSVIGLIGTFILCLCLMNLSTKLQEKITFVSNLAANF
                     AGIPLAFSFIILLGNVGVLKMILPFLADFNLYSWWGLTITYTYFQIPLGVLFLYPSMK
                     EVKKEWLESAQLLGASSAYAWFKVALPFLRPSIASTFVILFANGMGTYETAYALTSSN
                     VNLLTIRIAALVSGDVFAKPNLGSALAVALGVLLVTAMLIIQKKGKVVQT"
     gene            6123..6953
                     /locus_tag="J8S10_002492"
     CDS             6123..6953
                     /locus_tag="J8S10_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9631059.1"
                     /translation="MKKLIKPILFCFVLYYLLPIIGTILYASSTKWSKSLLPSDFTLQ
                     WFQQLLTDREFIAAVGRSLLLAGVVLVTILLLMIPTIIWIHLYFPRLNRWLEKLLLLP
                     YALPGVILVTALLRTYAETGIPMFVVLVGALFITALPIVYLSLNNQMRLINLKELVDA
                     AETLGAPMSTIIIQVLFPNIRIGVTLVSLMIFSSVFGEYMLTNLLIGGRFQTVRIYML
                     RRMNENGHLASAVMVLYLLFMVGIALTTFMLTYRQKQQLSLKQTREEKQSKKKPLKEL
                     "
     gene            6960..7991
                     /locus_tag="J8S10_002493"
     CDS             6960..7991
                     /locus_tag="J8S10_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9631060.1"
                     /translation="MFLEIHDLNLFFDEKQILAIDEIQIEKGELVTLLGPSGCGKSTL
                     LRCITGLEQPKSGEIVLDNENIADKPTKDRNIGFVFQQYALFPTMTVFENVAFGLKVK
                     KLSPEVIQEKVFEMLSLVDMTEQADKNVQFLSGGQRQRVALARSLVTEPKVLLLDEPL
                     SALDARIRKQLQRDLRAIQQSLGMTMIFVTHDQEEAMRISDRIFVMEAGRVAQVSTSK
                     ELYQNPQSRFVAEFIGNYNRFEWYELNQYTHEFSAKGNRCIYYLRPELIQFEPVPQGV
                     KIPVLWKESFILGNIQRYVFQTLEGKEILVDRLNDREEKISDALYIQLKDILAIPVEI
                     DTQHFAQQS"
     gene            complement(8098..9371)
                     /locus_tag="J8S10_002494"
                     /pseudo
     CDS             complement(8098..9371)
                     /locus_tag="J8S10_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250512.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            9648..9857
                     /locus_tag="J8S10_002495"
     CDS             9648..9857
                     /locus_tag="J8S10_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631061.1"
                     /translation="MDVLREYSSLFTEAYLLEQFGYKIPFADYQQGVGTAAELSFYEG
                     ISQAVGRPVDAEHFEQRISSTGKSE"
     gene            9907..10623
                     /locus_tag="J8S10_002496"
     CDS             9907..10623
                     /locus_tag="J8S10_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HAZ9631062.1"
                     /translation="MIKEKIDSFVTIDDLQVGKPDPEGYLLCLKRLRVEQAVVVEDSP
                     VGAQAAPHMTVDVQALDADFFAFSGHKMCGPTGIGVLYGKRQLLEQMEPVEFGGEMID
                     FVNLYDSSWKELPWKFEAGTPNIAGAIDYLNEIGMENIHRYEQELVAYVLPKLQAIGG
                     ITIYGPQDPEHHTGVVAFNLDGIHPRDVATALDMEGVAVRSGHHCAQRFIDDFCLTNW
                     SFKQSMIMPFERLQCRGIFE"
     gene            complement(10525..11045)
                     /locus_tag="J8S10_002497"
                     /pseudo
     CDS             complement(10525..11045)
                     /locus_tag="J8S10_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            11333..11986
                     /locus_tag="J8S10_002498"
     CDS             11333..11986
                     /locus_tag="J8S10_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAZ9631063.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
BASE COUNT         3481 a         2207 c         2734 g         3599 t
ORIGIN      
        1 ataacgtgat tttttgctgt aatgacaagg ttttagctgt ttcagatacc atgtatccaa
       61 aaatagttta ttgagaaaat aggagagtat ttgatactaa ctagtaggaa aaaatgagat
      121 aaaaagtaaa tggaatcatt taaggtaatc tgaaataaaa aatatacagc cctgtggtac
      181 tttacctaca aggctgtata tattttttac tctcagcgtt tttgactccg tgtctgactc
      241 cgttttattg attttgaatg ttattcaatg accatttaac aggtcaaatt tgatgttttt
      301 gattccgtat gacgccgttt gatatctagt gatatagtga tttgagtcta catcgaataa
      361 gggaataaac caataaaaaa tgatttagaa tattaaaata acaaaaaaga ggactacctg
      421 tattagtcct cttttttgac cagattttga ccagtctatt ttacatccta gtatatttat
      481 atgagctaat tttatgatta aatggtaagt ttttccttgt gtgttttagt ttaaactagt
      541 gtgtaattca aaaatctata tggaaggaac agtattaaga atagaacagg gttctctaca
      601 tgatggtgct ggtttacgga ccgttgttta tttaaagggc tgcccattac gctgtgcctg
      661 gtgttcgatt cccgaatcac aaagcaagca gattgaaaaa ggatttggcc agaccatgac
      721 cgctgaagag gtaatggatg agattgagaa ggatgctgtt ttttactttc actcggatgg
      781 cggagtgacc attagcggag gcgaggcact ggttcaggcg gattttgcta aagaaatttt
      841 gcaaaaatcg aaatacattg gaatcaatac cgtactggaa accagctttt gtggtgctta
      901 taatgaaatc caaaaggtag ctccctatgt ggatacattg tttgtggatg taaaaatgtt
      961 taccagcaag ctccacaaac aatggaccgg cttagataac caacaaattt tgaagaatat
     1021 tcgtcgcttt ttaattgagt atcctaactg cgaagtgcga attcgagttc ctgtggttcc
     1081 aggtatcaat atgaacctga ccgagctgct gacgattgct tgttttgtgg cagatcttga
     1141 tcggttcgta ccgttagaat tactaccgta ccactgctat ggtatgcacg gttaccaagc
     1201 attgggactg gagtatccgt tggcagacac gccagcgcct tcacctaaag aaatgtttgc
     1261 attggcagat caactggctc gcacggttcc tcatttgctg gtcacagctt taaccaaaac
     1321 atttatttat ttattgaatc caagctttat cttatggata aatgaaagac actcactagc
     1381 tgcagccagc tcaagaatag agcttttgct gaagtcagtg agtgtctttt tacgatgttt
     1441 tttcgaagtt aatttgtcga atgaacactg gctcaatcgg tacatcttca ctgtttgtcg
     1501 gctgagctgc gatcgctgct acgatttcta acccttggta tacctgtcca aaaacagtat
     1561 aacgaccatc cagctccggt agtcctccaa gctccaagta tgcttgcttt acattagcag
     1621 gtcagcctgc gcctttgtgt tttgcacaat aaaaaactgg ttgccgttgg tgtgggggcc
     1681 gtggtcccct aaggccaagg cgccattaaa atgataaagt ccgcgatgca cttcatcagc
     1741 gaaaaagccc tcatagctgg aaacagcttc atcaccagaa ccatccaaag cgccaccttg
     1801 aataacaaat tccttaatga cacgagccga aaggtgtgtt gtcataaacg ccttgctcag
     1861 ctagggagcg ccagttggct acagccaggg gagcttggtc aggaaataag cggagacgaa
     1921 tttcaccagc atcggtgacc agcacacaaa cttcttcctg ctgcggtttt tctaattgaa
     1981 agagaggaag gtttgcaact gaaacgcctt gatcctgcca tcaaatatcg aaaatccgcc
     2041 actcgacctt cgcctgatca ccaaggcgag ccattcccaa taaaacggta taggcggttt
     2101 catccgcttg aaaggtcaat tgcagctgtc ctcgtaaatc gttgtagtca tctggggcgg
     2161 ctacttgata aaaaagatga aactgcgcat gcaaatattc caaaggctga tctttaaagg
     2221 ctgcaaaata agcctgaact ttttcccgct gcaagctgtc agccaccaaa aaattttcca
     2281 gttgttgttt tggaacggct gctaacaagg atcggcaaac cgcctcaatt ttcaacgcat
     2341 cccaatgtcg cgcaattaaa taatggatgg gtgcctcttg attgtagtcc cacaggttgc
     2401 tcattttttt caccactttc ttctattata taggaatcac aaaatcggca gcggcgtcag
     2461 gcggcgttct tttccttgaa tgactagcaa cttttctacc tgacagtctg ccaacagctg
     2521 actcattttt ttaaagccca gctgataatc ttcggcaaca tgagcatccg agcctaaggt
     2581 aaagagcttt ccgccgacac tttgatacaa aggaacggca taacggtaaa ggtcttcgtt
     2641 gccgtatttc aagaagctct tggcatttaa ctccatcgcc aattctcgtt caacaacctt
     2701 tttgaaaatc gttagcagct gagcctcaaa atgctccgcg aattcttccg ctgtgaaggt
     2761 gaagcggcgt aatccataat caaagtgagt caaaatatct ccttctggaa aatccgtcaa
     2821 gacctgcaac atctgatcaa aatattcctt ggtagtttga atgggatctt tggttaaaac
     2881 cacatcgtcc atataatcaa agcggccatt ttgatgaata cttaccagct ttaaatcata
     2941 aggatgctga gcgaggtaat ccacgatccg ctcttcttgt cctggaacaa cgccaatctc
     3001 gatacctcgc agaaatttgg tggaataggt ttcttttaaa gagtccagtt tgtttatata
     3061 ggctggataa tccggaatgt catcttttcc ggtagatgga ttgtttaaat caaagtgatc
     3121 cgtagaaacg aaaaactccg gctgataggc taaatagttt tcaaattttt cctctgaatc
     3181 aaaggaaaaa tacgtgtgga gatgctgatc ataatactgc atagggagcc tccttttttc
     3241 tactatcata ccgcaaaagc tttagaaggt taacgggaat tcgtcgaaat ttacaaacca
     3301 tatacaacct ttacattgtt catgaaacct tttcaagaaa ctgattctct cattacaaag
     3361 ctttgttaga atggaattat cgaaagggga gaagaatgaa tgaaaatgaa tgaaaaaatt
     3421 cgtaacatga ctatcggttt attttgtgca gcaacagtaa gtatcctgct gacaggctgc
     3481 ggctcaggtg aagcaacgaa gcaatcggct gcggcagacg actctttaga tacgattata
     3541 gaaaaagcca aggaagaagg agagattgcc agcttgggaa tgccggatac ttgggcaaat
     3601 tgggtaggca cttggaacga ccttgaaaaa gaatacggct taagtcacgt ggatacggat
     3661 atgtccagtg cagaagaatt ggctaagttt gaatcagaag gaaaaaatgg aaccgccgat
     3721 attggtgatg tcggtatcag cttcggtccg ttggctgaaa gcaaagagtt aaccttacct
     3781 tataagacca actattggga ggaaattccg gattgggcaa aggatgatga tggggattgg
     3841 ttgttaagct atacgggaac catttccttt atcaccgata aagagaatgt gaagcaagca
     3901 ccgactagct ggaaggagct gcaagagggt gactatcaag ttagcgtggg ggatgtgacg
     3961 attgccaacc aagcacaatt tgctgtattg gctgcggcga ttgccaacgg aggtgacgaa
     4021 aaggatattc agccaggtct gaattactac aaaaaaatgg cagaaaaagg ccgtttgtcc
     4081 accgttgatg ccagcgtagc aaatcttgaa aaaggtgaaa tcgatgtggc agttgtttgg
     4141 gacttcaatg gactaaatta tcgtgaccaa attgactccg agcgttttga ggtaactgtg
     4201 ccaacagacg gctccatcat tagcgggtat acaaccttaa tcaataaaaa tgcccctcat
     4261 cccaatgcgg caaagctagc acgggaatat attttatctg atgaagggca aatcaatttg
     4321 gcaaagggct atgcgcgacc tattcgcaag gtagagctgc ctaaagaagt agctgaaaaa
     4381 ttactgccgg aggatgctta tgaagcggcg gtgccagttg aagacaatga agcttggaac
     4441 aagacctctg tagagcttcc agagctttgg caggcggagg tactgaccta tgcaaagtag
     4501 acttgacaaa ctgattgtag ttatactaga cggctgtcgc tacgacacag ccgtcgccca
     4561 gcttgggttc atgaatcatt tagttgagca ccagcaagca agcttattga aggtaaaaag
     4621 tgagctgccc agcaattcac gtccgttata cgaagtactg atgaccggcg ttccagccta
     4681 tgaaaatggc atctatagta attaccatgc tcagcgatcc aaagagtggt cgctgtttga
     4741 attagttaag gaagctggcg gaaaaacagg agccgccgct taccactggt acagcgagtt
     4801 gtacaatcaa gccccctata atcgtttggt tgatcgcatc cagcatcagg aggagcgact
     4861 gattcagcat ggcatctttt atagtgagga cacttaccct gattcgcatt tatttgcgga
     4921 tgcccattat ttagtgaatc agtatcagcc agactttttg gtcgtacatt cgatgaatat
     4981 tgatgatgtc ggtcacaaat ttaccgccga ttctcatgaa tatgcagcag cggttaatca
     5041 ggcggacaga ttattggcta tttaccttcc tgaatggctg caaaaaggtt atcaagtcgt
     5101 ggtgactgcg gatcacggga tggatgcgca cggactgcat ggcggcagct tggctgcaca
     5161 tcgtgaagtt cctttttatt tgatttcaaa taaacgccaa aagctgaagg aacaaactgt
     5221 accacagctg ctggcggctc cattgttttg ctggttatta ggaattgcac cgtcagagaa
     5281 aatgcaggac attcaagaat tgatgagggg atgaaagaga tgaaaaaacg cttggttctg
     5341 gttcctgcct cctttatctt ctgtgcattt ttactgctgc cgctgctttt tatggttctg
     5401 tgcagcttgc acagtgattt aactaaccag tggacattgg ccaattacag tgatattttc
     5461 agcaacaaat attacacaca ggcctttgtt aacagcgtac tgattgctgt cagctccagt
     5521 gtgattgggt taatcgggac gtttatttta tgtttatgct taatgaatct atcgactaaa
     5581 ttgcaggaga aaatcacctt tgtttccaat ttggcagcta attttgctgg gattccgctg
     5641 gcattctctt ttattatttt gttggggaat gtaggtgtgc tgaaaatgat tttgccattt
     5701 ctagcggact tcaatttgta ttcttggtgg ggattgacca tcacgtatac ctatttccaa
     5761 attccgttag gggtcttgtt tttgtatccc agcatgaagg aagtgaaaaa ggaatggctg
     5821 gagtccgcac aattgctggg cgcttcatca gcgtatgctt ggttcaaggt ggctttgcct
     5881 tttttgcgac catcgattgc cagcaccttt gtcatcttat ttgctaatgg catggggacc
     5941 tatgaaacag cgtatgccct gaccagcagt aatgtaaatc ttttaacgat tcgaattgcg
     6001 gctttagtgt cgggagatgt gttcgccaag cctaatttag gcagtgcgtt ggcagtcgct
     6061 ttaggtgtcc tgctggtaac ggcaatgttg attattcaaa agaaaggcaa ggtggtgcag
     6121 acgtgaaaaa gttaataaaa ccgattttgt tctgctttgt cctgtattac ttgctgccga
     6181 ttattggaac gattttgtat gccagctcca ctaaatggtc aaaatcgctt ttacctagtg
     6241 attttacctt gcaatggttc caacagctgc tgacggacag ggaatttatt gctgcggtgg
     6301 gtcgctcact tttattagca ggtgtggtct tggtgacgat tctgttgttg atgattccca
     6361 ccattatttg gattcatttg tatttccctc gtttgaatcg ttggctggaa aagctgctcc
     6421 tgctgccgta tgctttacca ggagtgattt tggtaacggc tttgcttcga acgtatgctg
     6481 aaactggtat cccaatgttt gtagtgttgg taggtgcatt gtttattacg gcgttgccga
     6541 ttgtctatct tagtcttaac aaccagatgc gcttaattaa tctgaaggaa ttagtggatg
     6601 cagcagaaac cttgggcgcc ccgatgtcta cgattattat ccaggtgctg tttccaaaca
     6661 tccgtatcgg tgtgacccta gtttctctga tgattttttc ttcggttttt ggggagtaca
     6721 tgctgacgaa cctgttgatt ggcggtcgat ttcagacggt acgcatctat atgctgcggc
     6781 ggatgaacga aaacggccat ttggctagcg ctgtgatggt tttgtatttg ctgtttatgg
     6841 tgggaattgc tttaactacc tttatgctga cttatcgaca aaagcaacag ctgtccctta
     6901 agcagacgag ggaagagaag cagtcgaaaa agaagccctt aaaggagttg tgacggaaaa
     6961 tgtttttaga aatacatgat ctcaatctgt tttttgatga aaaacagatt ttagctattg
     7021 atgaaattca gattgaaaag ggtgagctgg ttactttact aggtcccagc gggtgcggaa
     7081 agtctacgtt gctgcgctgt atcacgggat tggaacaacc aaagagcggt gagattgtgc
     7141 tggacaatga gaatattgcc gataagccta cgaaggatcg caatatcggc tttgtttttc
     7201 aacagtatgc attgtttcca actatgactg tttttgaaaa tgtagccttt ggtttgaagg
     7261 taaagaagct gagtcctgag gtgattcagg aaaaggtttt tgagatgcta tcattggtgg
     7321 atatgacgga gcaggcagat aaaaatgtcc agtttctttc tggcggtcaa cgacaacggg
     7381 tggcactggc tcgctcattg gtcactgaac cgaaagtcct gctgctggat gagccattaa
     7441 gtgctttgga tgcccgaatt agaaaacagc tgcagcggga tttgcgcgct atccagcaat
     7501 cgctagggat gacgatgatt tttgtgactc atgaccaaga agaggcgatg cgaatcagtg
     7561 atcggatttt tgtgatggaa gctgggcggg tggctcaggt ttccacctcg aaggaattgt
     7621 atcagaatcc tcagagccga tttgttgcgg aatttatcgg caactataat cgtttcgaat
     7681 ggtatgagct gaatcagtat acccacgagt tttccgctaa gggcaatcgc tgcatttatt
     7741 atttaagacc ggagctgatt caatttgaac cggttcctca gggggttaag attccggttc
     7801 tatggaagga atcatttatt ttaggcaaca ttcaacggta tgtttttcaa acgctggagg
     7861 gcaaagaaat tttagtggat cggttgaacg atcgggaaga gaaaattagc gatgccttat
     7921 acattcagct gaaagatatt ctagcaatcc ctgtggaaat tgatactcag cattttgcac
     7981 aacaaagcta gtgtatagtc ggcaaacatt tctggctctt tgtcaaatag gactgataga
     8041 gtgatataag aacatctaag gtagaattga ttttctgctt tagatgtttt tttatgttta
     8101 ataagtgatc agatgattga ttaagaaaat tctggttctc atcctaaccc gtaagctatt
     8161 cgtttcaatg ctttgatgtg ggtatgcaga ttttctattt tgccatttga gtaaggcaac
     8221 tctaaggcta aacgaatgcc ggattcatag tttataaacg ctttttttat atgatgcagt
     8281 tctcttggaa ccgacttggg cattgttttt acaagctgaa agaagatgtc cgcttctttg
     8341 tcataaaaag cttgaagaat ttcttgatag taagcataag ctattcgtag ttcatcagaa
     8401 gtagaaagta gacgttctac gacttcactt tcggttaaat aggcccaacc aaaattacgc
     8461 cattttgtcc atttatcata aacaagcgtg tcctgtcgtt tgatcagaag tcgagataaa
     8521 gccttcactt gtcgatagtg tttggcttgt attggatcgt ttcggtcgaa gcttttcatg
     8581 actcatagtc aaatatcctt aaaactgcga atgaggtgct tgacgatgtg aaagcgatcc
     8641 acaacgagtt tggcatgagg aaagcactct tttatcagca aagcataaga ggcgttcata
     8701 tctgttacga gtatttttac gtttaaacgt gcacgtcgtt caaattgcat aaaataagaa
     8761 atgagatctt tcttcttacg tgaaggaaga atatccagta atttcccagt atcgccatcc
     8821 atacaagaaa aagaataggg accgacttga tttttcaatg aacgaaattc atctaccaat
     8881 gaacagcgag gcaaccaatt tattttcacg tttgtcatgg ggagcagaga agcgagtgtt
     8941 cgcgaaacgg ttgaccaaga aacgccgcaa tgtttagaaa tcgtcgtcat tgcttgtttt
     9001 tcagtcaatt cctccaatat tttataatgt acttgtttgg cgataaaaca gtttttttca
     9061 acaatgtagg tattcgccgt aaaataggtg tgacagccac gacagaggta ccgttgcttt
     9121 gccaaagcaa gataagtccg ttgattcgca cacttattga gaaggaccag cgattttttc
     9181 tttccgttct taacgatcag cccatgttga ttcacctgtt tacactgagg acagggctga
     9241 atcgttttaa tgagcgtggc agaaacaacg atactgttga ttgaatgtat ttttttcttc
     9301 tcgacatgag tgatttgaat gtttccatct ttgattccta gtaatagttt gataagatga
     9361 agatcaggca tacagaacgc tcctttgatt gtgttgtggt gattcaattc taacggagct
     9421 tctgtatgtt ttgttttttt atgctcaaaa ggactgatag aatgatttac tatcagtcct
     9481 agaaattata gcgccacatt tctttcacct ttgacttttc agacggcagt ttttatgctg
     9541 atactgtaga gagagcagga cacagctttt gcttgttttg ggtaaggggg aaagaagatg
     9601 accaaagcac ttatttttga ttttgatggg acgatgattg acagtgaatg gatgttttac
     9661 gagagtattc atcactattt actgaagcct atttactgga gcagttcggc tataaaattc
     9721 cttttgcaga ctatcaacaa ggtgttggga cggcagcaga actgtccttt tatgaaggga
     9781 taagtcaagc ggttgggaga ccagtggatg ctgaacattt tgagcagcgg atcagcagca
     9841 ctggaaaatc ggagtagtct caattctgaa ctgcgggagc tagactattt ttttgaagca
     9901 catccgatga ttaaggaaaa aattgattcc tttgtgacga tcgatgatct tcaggtcggc
     9961 aaaccagatc cagaaggtta tttgttgtgc ttgaaacggc tgagggttga acaggctgtt
    10021 gtagttgagg atagtccagt cggtgcccaa gcagcaccgc atatgacagt tgatgtacaa
    10081 gcgttggatg cagatttttt cgcctttagc gggcataaaa tgtgcgggcc gacaggaatc
    10141 ggtgtattat atggcaaacg tcaattgtta gaacaaatgg agccagtcga attcggcggt
    10201 gaaatgatag attttgtcaa tctttacgat agttcatgga aagagctgcc atggaaattt
    10261 gaagctggta ctccgaacat tgcaggagca atcgattact tgaatgagat tggtatggag
    10321 aatattcatc gttatgagca agaactggtt gcctacgttt tacctaaatt acaagcgatc
    10381 ggcggtatca ccatttacgg accgcaagat cctgaacatc atactggcgt ggttgctttt
    10441 aatttggatg gcatccatcc ccgtgatgtg gcgactgctc tggatatgga aggtgtcgct
    10501 gtacgttcag gacaccattg tgcacaacgg ttcatcgacg atttctgttt gactaattgg
    10561 tcgtttaaac agtcgatgat aatgccgttt gagcggctcc aatgtcgtgg aatctttgag
    10621 taagagtttc caatatcgct tgagccgacg gtacttcttc tgattttcag attacgtgat
    10681 tgattttcgt acagttctat gagaatcgcc tgtttcagtt cctttgttag ttgatgatgt
    10741 tcatcaacta agtccgtttt cgcagaaaag gtctgcccac aatcatagca tagaaaacgg
    10801 gtacgtttta attctaaaat agtcaacttt tctttgactt tcaacatctg agtacgtgtc
    10861 gtataggaac cgttgcggat aatacgaatc gatccacagt gttcacaatg ggaaggtgag
    10921 tcatccaatc tccctttaat aaactgcgct tgaacgcctt tatattcttt ttcaatcagc
    10981 cattcttcat caaaaaataa atgtttatct gttaatccga gtaattttct agtatgatta
    11041 tccatagagc gactcctttg gtagggtgat gttttggtcg actaaatttt accaaaagtg
    11101 agtctctttt tgagttgaaa cgaagaaaaa gtgttagtag aaaatcgcct tcgattttcc
    11161 aacaacacaa aatattatag aagccttttt tctaaaggat ttcaaggtgt ctgtttgcat
    11221 ttattaaaaa aaagaaaaag tattggcaac agaaggcgtc accaacacta gatattatag
    11281 agccataata tgctgtataa tatctagtgt ataggcttaa gtggaggtat atatgaaaat
    11341 attaactgtt gaagatgata atatgataag agagggaata agtgaatatc tttcagaatt
    11401 tggatatact gttattcaag ctaaagatgg aagagaagcc ttgtcaaaat ttaatagcga
    11461 tataaatttg gttatcttag acattcagat accttttata aatggtttag aagtgttgaa
    11521 agaaattaga aagaaaagca atttaccaat tctaatcttg actgcattta gtgatgaaga
    11581 atataaaatt gatgcattta ctaatttagt agacggatat gtagaaaagc cattttcatt
    11641 gccggtctta aaagctagaa tagattcttt aattaagaag aattatggac atttagagaa
    11701 gtttgaatat aaggatctat cggttaattt taatagctat acagctaaaa taaatggtga
    11761 agaaatagat gtaaatgcaa aagaactaga agtattaaaa tgtttattgg ataataatgg
    11821 acaagtgtta acaagaatgc aaattattga ttatgtatgg aaagatagcg aagaaactcc
    11881 ttatgatcga gtaatagatg tatatataaa agaacttaga aaaaaattac aattagactg
    11941 tataactact ataagaaatg taggatataa attggagaga aaatgaaaaa attaaagata
    12001 tttccaaaaa tgttcataca a
//
LOCUS       DADQDV010000082        11946 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.085, whole genome shotgun sequence.
ACCESSION   DADQDV010000082 DADQDV010000000
VERSION     DADQDV010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11946)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11946)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11946
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.085"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            27..2045
                     /locus_tag="J8S10_002499"
     CDS             27..2045
                     /locus_tag="J8S10_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAZ9631064.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     gene            2472..4886
                     /locus_tag="J8S10_002500"
     CDS             2472..4886
                     /locus_tag="J8S10_002500"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016183651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HAZ9631065.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            5234..6787
                     /locus_tag="J8S10_002501"
     CDS             5234..6787
                     /locus_tag="J8S10_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HAZ9631066.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(7168..8952)
                     /locus_tag="J8S10_002502"
     CDS             complement(7168..8952)
                     /locus_tag="J8S10_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9631067.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(8967..10688)
                     /locus_tag="J8S10_002503"
     CDS             complement(8967..10688)
                     /locus_tag="J8S10_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9631068.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            10788..11549
                     /locus_tag="J8S10_002504"
     CDS             10788..11549
                     /locus_tag="J8S10_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAZ9631069.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
BASE COUNT         3914 a         2162 c         2424 g         3446 t
ORIGIN      
        1 gataaattga agttggagga tagaagatgg aaaacattgc aagaaaagaa cggagacgtt
       61 tagaacagac caaacgtttt cgaaaagcaa aacgaggggc agcaatcgtg ggaactgcga
      121 tggtaggctg ttctgtcgct gccccattag tacagccggt tcctgttcaa gcggatgaaa
      181 cacctgttca gttcggcgca agaatcaata cagcggcatt tatcacagaa attgctactt
      241 atgctcaacc aatcgctcaa gccaacgatc tatatgcatc agtgatgatc gcacaagcag
      301 ttgtagaaag cggttggggc agtagtgcgt tatctcaagc accttattat aatctttttg
      361 ggataaaagg cagctatcaa ggacaaaccg tctacatgga tacgcttgaa tttttaaata
      421 atcaatgggt aaataaaaag gagcctttcc gacaatatcc ttcttttgct gaatctttca
      481 atgacaatgc ctatgtactt agaaatactt catttggcaa cggttattac tatgccggta
      541 cttggaagag caacacgaaa tcctatacag atgcgacagc ttgtttgaca gggcgttatg
      601 cgactgatcc tggttacgca ggcaaattaa ataatatcat cgcaacttac ggattgaccc
      661 aatatgatac accagctagc ggaaacgcag gcggtggagc gactacaggt ggcaataata
      721 ctggaagtgc aggtagtact ggcggttcaa gcaattctgg taatacaaac tcaggttcag
      781 caacttcgac cacttatact gtccaatctg gtgattctgt ttggggaatc tcaaataaat
      841 tcggtatcac aatggatcaa ttgatccaat ggaacaacat ccaaaacaat ttcatttatc
      901 caggacaaaa actgacaatc aaaggtagcc aggaaaatgg ctcttcgacg aataattccg
      961 gtaacaatac caactcttca ggaaatgctg gtacatcaaa cggaggacaa acaactggtg
     1021 cgaaatacac tgttcaatct ggtgattctg tttggaagat ctcaaatgat cacggaatta
     1081 cgatggctca attgattgaa tggaacaata tcaagaacaa tttcgtttat ccaggacaac
     1141 agctaatcgt atcaaatggc ggttcttcta atgctggagc aaatactggc tcaaatactg
     1201 ggaatacaag tggctctagt tcgtccagct caagttcttc taatacagct tcaggaacga
     1261 aatatacagt taaagccgga gactctgttt ggagcgtctc aaataaatac ggaattacga
     1321 tggctcagct aatccaatgg aacaatatcc aaaataactt tatctaccca ggacaacaac
     1381 tgactgtttc aaacagtgga tcaacaaaca gcacgtcagg taatacaggt tcgtcaacca
     1441 atacaaataa cagcagttca gttaatactg gcagcagttc gtctcaaggc acttataccg
     1501 tgaaagcagg tgaatctgtt tggagcgtgg caaataaaaa cggcatcacg atggatcagt
     1561 taatcgaatg gaataatatc aaaaacaact tcatttatcc aggacagcaa ttgatcgtta
     1621 aaggtggaac ttcggcaaat acaaatacag gttcaactac ttctgcagcg aaaccaaata
     1681 caccgaatac gtctgctacg acaagtacat catccactgg taatacgatg tataccgtga
     1741 aagcgggcga gtcagtttgg agcgtagcga acaaacatca tatcacgatg gatcagttaa
     1801 tcgaatggaa taatatcaaa aataatttca tctatccagg acagcaagtg attgtgaaga
     1861 aaggttcatc tcaatcaaca aaccaacaat cagttactgg ttcgaaaacc tatactgtga
     1921 aatctggaga atctgtttgg agtgttgctg acagtcatgg aattacaatg gctcaactaa
     1981 tcgaatggaa caatattaag aacaacttta tttatccagg tcaaacgttg attgtagcta
     2041 aataaaatag ctgttcgaag aaataacgat tgaattccac aaaaatattt gttactataa
     2101 ggctacttaa atatgacaac acttgaaaag gaagtagtaa aaagactgaa gtttcagaga
     2161 gcgcatggct ggtgagaatg tgcacggatg cttttgaact cgcctttgag ttgcccttgc
     2221 tgaatacccg agtaagcaag cggcggtgac ggccgttaca acgttcgagg ccttttcact
     2281 aaggtaaaat taggtggtac cgcgtagatt acgtcctata aaaagagcaa tctttttata
     2341 ggattttttt atttcttttg tgaagtttga gaaaacaaag caaaaggaaa taaaaataaa
     2401 cagattctgc cggttttttc gttatattta taatagaaac aagtgttttc aatagaacag
     2461 gaggacagca aatgagttac aatcataaag aaattgagaa aaaatggcaa aaatactggg
     2521 caaaaacgaa tactttcaac acccatgatg atcctgaaaa gccaaaattt tacgcactgg
     2581 atatgtttcc ctatccatcc ggtcaagggc tacatgtagg gcatcctgaa ggttatacgg
     2641 caacggatat cctttcacgt gtgaaaagaa gtcaaggata caacgtgctg catccaatgg
     2701 ggtgggatgc attcggtctg cctgctgaac aatatgcgct agatacagga aacgatccag
     2761 ctgagtttac ccaaaaaaat atcgaaacat tccgacgcca aatcaattct ttaggattta
     2821 gttatgactg gaatcgcgaa gtgaatacaa ctgatccgga gtattataaa tggacacaat
     2881 ggatctttac gaagctttat gaaaaaggtc tagcttatga agcagaagta gcggtaaact
     2941 gggtacctga attaggaaca gttatttcaa atgaagaagt gatcgatggg aaaagtgaac
     3001 gtggtggcta tgatgtagtc agaaaaccaa tgcgccaatg gatgctgaaa atcactgctt
     3061 atgctgatcg cttattggat gatctagaat tagttgattg gccagaaagc attaaagaaa
     3121 tgcaaagaaa ttggatcggt cgttcagtag gagcaaatat tgaatttaaa gtggctggta
     3181 cggataaatc ctataccgta tttacgacac gaccagatac tctattcggt gcaacttact
     3241 cggttcttgc acctgaacta gatcttgtta gagaaattac gacccctgaa caaaaagctg
     3301 ctgtagaagc ttatatcgaa gagacagcta aaaaatcaga tctaaagaga acggatcttg
     3361 caaaagaaaa aacaggagta tttactggtg cttatgcaat caatccagtt aatggcaagg
     3421 aaatcccaat ctggatcgcc gattatgtat tatcttcata cggcacagga gccatcatgg
     3481 ctgttccagc acatgatgaa cgtgactttg aattcgctca aactttcgga ctagaaattc
     3541 ttccagttat cgaaggtgga gatgttgaaa aagctgctta cacagaagat ggtacgcaca
     3601 tcaactctga atttctagac ggcatgaaca aacaagaagc aatcgataaa atgaatgaat
     3661 ggctagaaga aaatggcgta gggaaaaaag aagtcagcta tcgcttacgt gactggctat
     3721 tctcccgtca acgttactgg ggtgaaccaa tcccaatcat ccattgggag gacggaacag
     3781 tcacagctgt cccagaagaa gagctaccat tacggttgcc taagacaaaa aacatcaagc
     3841 caagcggtac tggagaatct ccattagcaa atatcgagga gtgggtcaat gtcgttgatc
     3901 ctgtaacagg taaaaaaggc cgtcgcgaaa cgaatacaat gccacaatgg gcaggaagct
     3961 catggtatta cctgcgttat atcgaccctc ataacaaaaa agaactagca gattatgaaa
     4021 agttgaagcg ttggctacca gttgacatct acattggtgg agcagaacat gcggtacttc
     4081 atttactata tgcacgattc tggcataaat tcttatacga tatcggtgtt gttcctacaa
     4141 aagaaccatt ccaaaaacta tacaatcaag gaatgatctt aggcgaaaac aacgaaaaaa
     4201 tgtcaaaatc tcgtggtaat gtagtcaatc ctgatgatgt ggtcgaaact tacggtgcag
     4261 atacactgcg catgtacgaa atgttcatgg ggccattaga tgcttcgatt gcttggagcg
     4321 aaaatggctt agaaggaagc cgtaaattct tggatcgtgt atggcgtttg atcgttgatg
     4381 agaacaataa aatgcgtgac cgtatcacta cattgaatga tggcaagctt gataaagtgt
     4441 atcatcaaac agtgaaaaaa gtgacagaag actatgaaaa tcttcatttc aatacagcaa
     4501 tctcccaatt gatggtcttt atcaatgaag cctataaagt ggacgctctg ccttatgaat
     4561 atatcgaagg atttgttcaa ctactcgcac cgattgctcc tcacatgggt gaagaactat
     4621 gggcaatcct tggaaatgat ggtggtattt cttacgcacc atggccaaca tacgatgaag
     4681 cagcacttgt tgaagacgaa gtagaagttg ttttccaagt aaacggtaaa gttcgtgcga
     4741 aaagcaatgt tccccgagac ttaggaaaag atgagctaga aaaagcagca ttagccaatg
     4801 aaatagtgca agaatatatt gaaggcaaaa cagtcagaaa agttattgcg gtaccaaaca
     4861 agttagtcaa tatcgttgct aattaattgg ctctttgtca ataaggactg atgagttgtg
     4921 caaaatcaaa tctgggccag aatgaacttc attctgtctc agattttttg ttatttcaaa
     4981 ttgattaatt gattgatcaa aaaggttttg attttcatgt tctcaaacac gttcaatgtc
     5041 tttttcttct gaatggtctt gtaagagatc tctgtaatca tcaaattttt gtctattaat
     5101 cttagtattt tttgatgtat aaactacctg aaattgagag tacataccaa attcataaat
     5161 tttttattag tgggactagt gattgtatgg attttgacgc ataatgaatg aagtatgaga
     5221 aaaggagaga caaatggatc aagaactatt tattatcgaa gtattatcag ctaaacaaaa
     5281 aattatcgag aaagcgaaaa aaagagcgaa aagaataatg ttcaagcttt taagcttagt
     5341 atttttctct ggtttgcttt ttttcggagc tgtatcgttc ctatatcgcc atatgagtgc
     5401 agtagtccgt tcagctgaag ggatgcaaaa attaaataat ttgtatcact tttcgtgggg
     5461 agttggcgga ataacaattg ttgtgcttat tgtttttctt ctacttattt ggctccgtta
     5521 ccatcaattg tcgcgtcatt tcgatcaatg gcttagtcaa agagcacaac agtttttaca
     5581 taataaacca acttctcaag atgatgacta tctttatttt gagaagactt cgacgagtca
     5641 agcttttcgg atacaaaaaa gtgattgcca gttattgctg agatcacttg atgatttacc
     5701 tatctactta ggcgaaagca aatcaaaatt cggaatgaac acattccata tttttttact
     5761 agaaaacgaa cccagatggg aaaaaagcca gtcttcgcct ggtggatacc tgacaactaa
     5821 gatgagtaca ttagtcactg gttttttcct cattctttta gctggaacaa tctattatgg
     5881 gagatacact cagccaaaaa tgtcttctca tataaatgct gcttctcaca tgacaatgaa
     5941 ctcaactaac gatacgcata tacaaaagac aaatgaaggg ttgttagctg atcctaagca
     6001 aaaggtaaat ttgacaacac aaaagataaa tgatctcaaa cttgatacag agacgcactc
     6061 tctctatatg acaacagata gtggtgctaa ttgggtattt gtgccgattg attcgcaatg
     6121 gttgcgtttt ggcgaataca ccctgacaac ggggctgatt cctgaaggtt attggatgga
     6181 caacacatat gatatttccg ccgatttctc atggtttatc tattcttctg gggatgatgt
     6241 acgtctgctg acttcaagag ataatggtaa aacatggcaa acgtctatta tcacccaatc
     6301 agttcagccg atacgttatc gaaaagcggt attttatggc aacgatggtc tatttatctg
     6361 tacatcagcc agtgggatgt ctgcagaaac tttgtacatt tacactacta tggatggcgg
     6421 aatcacttgg ataaaaagtg gaagtacaat gatcaatcag ccagtacaaa atgtcagctt
     6481 cgttacaact tctttaggtt ttgtttcgac acgtgaaagt ttgttttata caaacaacgg
     6541 aggacgctca ttcaaagaat cagttctgtc gattccggaa aactatcaga caggggggat
     6601 agatcttttt caatcaccaa atgaagttac tcaaataagc gcgaatacgt tagagacaaa
     6661 attttatttg ttgaaaaaag gaccaatcga tgcagggaaa atgtttgcct gcctcttccg
     6721 ttcaactgat aacggggaaa catggcaatt cgttcagcaa ctatcgcaag tagaacaagg
     6781 agattaaaga agagagattg tgagcctgac gttcagcacc gagtcacaag aaacaaattc
     6841 aaaaaacagc ttctcatatt tgttgaatag tgtaactcgt gattcggagt tgacaagagc
     6901 aacaagaagc gattttgaag tatagcttct cgtattttac aagatcgtgt cttattgccg
     6961 ataggttgtc tcttgaacac cgtttattcg taaaaaggga ttgtgacaag tcttttgtca
     7021 ctacttaccg aacgaaactg aaggagctat ccaaaaagta tcattagtat tattctttgt
     7081 gtttctagtg gcaccactag tacatttaaa aaagctatcg atcatggact aatcatacat
     7141 gatcgatagc tttttagata atgtttgtta cgctatctga aattgactat tataaagact
     7201 ggcataaagc gttggtgatt ggagtagttc agaatgtgtt cctttttcga cgatatcgcc
     7261 attcttcatt acaaggatca tgtctgcatt ttcaatcgtt gacaaacggt gtgcaatcac
     7321 aaaacttgtc ctatcttttg tcacagcttc cattgcttgc tgaatcaatg cttctgttcg
     7381 tgtatctacg ctagaagttg cttcatctaa aataacgaca ggaggattcg ctagaatgac
     7441 tcgagcaatt gtcaataatt gttgctgtcc ttgagataac gtgccgtttt cgctagaaat
     7501 gatcgtatca tatccgtctg gcagtgttcg aataaagtga tcacattgtg cgatttcagc
     7561 cgcttcgata atttgttctc ttgtggcatc cattttcccg taggcgatat tatcagctac
     7621 cgttccttca aacagccagg tattttgtaa aaccatccca aaagaacgac gtagttctcc
     7681 acgtgaaagc ttggtaatat caagaccgtc gaattcgatc tttcctttat tcagttcata
     7741 aaaacgcatc agcagattga ctaaagtcgt ttttcctgca ccagttggac caacgatcgc
     7801 taccgtttgt tttggcttta ctgaaaaatc gacttgattc atcaatattt tatctgatgt
     7861 gtaaccaaac tgtacatttt tgaaagctat ttttcctttc ggttgttcta aaagtcttgc
     7921 atctggaagg tctggaattt catctgtttc atctaatatc tcaaatatcc tatcgattgc
     7981 tgccattgcg gattggatcg agttgatcac ataagaagcg gtagaaattg gttcagaaat
     8041 ctgattgatg tactgaagat aagcttgtaa gaagccgatc gtcacaccac ctgatagaac
     8101 aagcatagca ccgaataccg cacttatgat gaaggcgagt tgattaatga aacgaatggc
     8161 cggatagata gcacagttca taaattgagc acgtttaaaa gcgttgtatt gctttttatt
     8221 tacttcgtgt atagcagctt ctgcatgagc ttgctgattg aatgttttga ccactagatt
     8281 accagctaag atttcttcca ttcgattatt taaaacaccc agttcatact gattctgttc
     8341 agaaatctgt ttgtttttgt tcgcaatctt agttgtaaca attgaactgc caacgatcag
     8401 caataagacg agcaaagtaa gcttgctttc gatataaaac agcatcagac cagcagcagc
     8461 tattgttacg acagaagtaa aaaattgatt gatacctgtc aataacactt gagaaagttg
     8521 attgagaccg gtagttgtcc gactaatgat gtcacctact tgatgattgt caaaaaacga
     8581 catcggtaat gttttgaatt tttttgtgat ttcttttcgc accctcaatg tgatcttttc
     8641 gcttaacgct gccattgtcc gttcctgaat aaatgaagtg atgctgctta agactgaaca
     8701 gccgatcagc aataagacag ggaacaacaa tgcttgtttg atatcactga aagaaagctg
     8761 tccaatacct gtttttctta tttctgataa gagatcatcg atcccgattc ccatgatcaa
     8821 gggcatggct acgactaata ggttcccgaa taaactgcat agaaacaatc cgtaaaaata
     8881 tttatgttca ggtttgatca ttttccaaaa acgtatcaaa gcacgcgtgt tcaacgtttt
     8941 tttcttttcc atcgtatccc ttctttctat attccttgtg attttgcaaa ctcctgataa
     9001 gtttggcaat tagacagtag ttcttcatga gtaccttgtc caacgatttt tccttcatct
     9061 aaaacaatga tgttatctgc ttgttggatt gtactgaggc gttgagcaac aatcacgaga
     9121 gttttctccg acatgtgttt atgaagggct gctcttaatg ctgcatctgt tttatagtct
     9181 aaagcggaga aactatcatc gaatacatag atctctgctg gtttgatcaa cgctcgagca
     9241 atacatatcc gctgtttctg gccccctgaa taattagaac cgccttgagc aacaaagctg
     9301 tccaatccgt caggaagggt gtccactagt tcttctaatt gagcgatctt gatcgcttta
     9361 gacaactctt ctgttgaggc atattcattt cccatctgca agttgcttaa aattgtcccg
     9421 ctgaataaga aagccttctg agggacataa ctgatgtggg agcggatctg ttcttgagtc
     9481 atttgagtaa gaggaatacc accaagggtt acttttccta tcgtagggtc actaagtctc
     9541 aagagaagtt tcgccaaact actttttcca gatccggtcc cgccaacgat cgctgttgtt
     9601 tttcctttag gtattgtgaa atcaatatct tctagaactg gatcagagat ttcagtatat
     9661 ttaaatgtga catgttcaaa agcagctgca tttgtctgat caaaggttgg ttcagctact
     9721 gttttgatcg tctcttcctc aatttcgatc tctgcttgca gtatttcttc tatccgtcgt
     9781 aatgaggcaa acgatttagg gataatgacc aataccatag ctgcgatcat caagtaagca
     9841 agtgtcagca tagagtattc gactacagca gtcacgacac cgatttgtaa tgctccttct
     9901 gctacaagat ttccgccaaa ccacaaaata gaagcataaa cgattcccat gagcaaaaaa
     9961 gcaattggag tgacccaagc aaatattcgg ttcactttga tcatttgatt agcatagtca
    10021 gcaaagctct tattcgttcg cttttcttca tatgattgat tatcaaaggc acggatcata
    10081 ttaatcccag taaagaattc tctcaatgtg atggtgatcc gatccatttt tggctggata
    10141 ctcaaagata aaggtgcccc tcgtttcatc agtcgataaa caatccatac ataaaaaaca
    10201 acagagatca atgtaaccca tgttagtaat agagaataac gaaacatcat gagaatggtg
    10261 aaaacgcaaa taaccggtgc tggtaagatc atttggcaaa ataaaacaat catttgctgg
    10321 acattatcga catcattcgt cattcttgtc aaaagagatc cagaactaaa acgactgata
    10381 tccttcattg acagctgttg gaatttacgg aaatatttct cccgcgtttg gaatccaaac
    10441 ctagcggaag ccaatgctga aaagtaacta gaggcaactg cagcgattgt tcctagaaac
    10501 gctacaagca gcatttcaac tccaattttt tttataactg aggcttcgcc acttgctata
    10561 cctgtgtcga tcagctttgc tactaatttt ggtacaccta atgtaccggc gatttctaaa
    10621 cagatcatca caaaggtaag gagagcgagt cctttgtttt tctgtaagaa tgtttttaag
    10681 atagacatat tattcctcct tttttcctga tacttttcga ttctatacct tcaagtaact
    10741 tgaaggtcaa tagaaaaaag aataaactga aaaagaggtg agaaaaaatg aaaaaaatgt
    10801 atacgattgg ccaagtatcg gaactatttg atttgccaaa atcaacgatc cgctattggg
    10861 atgaacaagg attaatccgt tcaagtagac aagaagagaa tgattatcga ttgtttgata
    10921 tcgatgatat ttttatgctt tatgatatcg ttttttatag aaaattagat ataccgatca
    10981 aacagatgaa gaatttatat ggaaaaacat tgacggagtt atatgagaca cttgatgaaa
    11041 cagaaagaag aatccataaa gaactggtgg tgatgaaaca aaaacaaaaa gagataaggg
    11101 agcaaaaaaa acagttgaaa ttgatgatcg atacaaacga ggaagaattt cctgtagaag
    11161 agatcccttt tgactgtatg atctcaacgg agtttgaaga tattgtggaa atcaaaaaat
    11221 ttctacctaa ctattcaagc tttgggatga tgagtatgcc agcttccagt tcacagacga
    11281 tgtatggatt ttttatcgac cctagtgaag tacatttatt tactcaagac gtgatttggg
    11341 agaaaaaaga tacggctgtt tatcgtcgat tcttattgaa atccgagatg aaccatgcgg
    11401 aacgtaataa tattttagaa atcagagaaa gaatgtatga aaaaggatgg aaaacaggag
    11461 aagtgatcgg ccagtatcta ttgacgaata cggatgaaaa caatatcaga actgaatatt
    11521 atcatgcatg gatagaaatg aaaaaatagg aaatatgtgt ttaagataac tcgaaaatga
    11581 tggttgtttt agttataaag aaaaattttc tggttcgatt acgggtttaa tgtgggggat
    11641 tattagtcgt ggatagatag aattttagtt ttttagagga aatatgtctt taaaaatgga
    11701 atggttgcaa ttcttagcga tatatacgat gtaattgtcc tcttaaaaaa gtatggaaaa
    11761 ataattgtat tgggtgttat gtataattca tggtgaactg agactaatga gaagaaaaat
    11821 tcatattgtt atgagtgaga ttgtatcaga tgagaatgat aaattaaata ggtgcataaa
    11881 agcattacac ttaaaataca ttgttgctta cattattaca atatgttaat aaggcaaaaa
    11941 taaata
//
LOCUS       DADQDV010000083        11787 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.086, whole genome shotgun sequence.
ACCESSION   DADQDV010000083 DADQDV010000000
VERSION     DADQDV010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11787
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.086"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            514..1077
                     /locus_tag="J8S10_002505"
     CDS             514..1077
                     /locus_tag="J8S10_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631070.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
     gene            complement(1138..1503)
                     /locus_tag="J8S10_002506"
     CDS             complement(1138..1503)
                     /locus_tag="J8S10_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631071.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(1579..1824)
                     /locus_tag="J8S10_002507"
     CDS             complement(1579..1824)
                     /locus_tag="J8S10_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAZ9631072.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            complement(1894..2148)
                     /locus_tag="J8S10_002508"
     CDS             complement(1894..2148)
                     /locus_tag="J8S10_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631073.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            complement(2312..2635)
                     /locus_tag="J8S10_002509"
     CDS             complement(2312..2635)
                     /locus_tag="J8S10_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631074.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            2822..2895
                     /locus_tag="J8S10_002510"
     tRNA            2822..2895
                     /locus_tag="J8S10_002510"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2856..2858,aa:Ile,seq:cat)
     gene            complement(3280..3777)
                     /locus_tag="J8S10_002511"
     CDS             complement(3280..3777)
                     /locus_tag="J8S10_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAZ9631075.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(3817..4626)
                     /locus_tag="J8S10_002512"
     CDS             complement(3817..4626)
                     /locus_tag="J8S10_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAZ9631076.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            4960..5817
                     /locus_tag="J8S10_002513"
     CDS             4960..5817
                     /locus_tag="J8S10_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HAZ9631077.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            5810..6712
                     /locus_tag="J8S10_002514"
     CDS             5810..6712
                     /locus_tag="J8S10_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HAZ9631078.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            6745..7095
                     /locus_tag="J8S10_002515"
     CDS             6745..7095
                     /locus_tag="J8S10_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HAZ9631079.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            7129..8067
                     /locus_tag="J8S10_002516"
     CDS             7129..8067
                     /locus_tag="J8S10_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HAZ9631080.1"
                     /translation="MRYYFVDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPD
                     DIFVGTEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLI
                     TCIDRKTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAAR
                     KTTENEELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQ
                     RQTEKMIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTG
                     GLPGKSSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            8145..9038
                     /locus_tag="J8S10_002517"
     CDS             8145..9038
                     /locus_tag="J8S10_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAZ9631081.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKVAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            9076..9639
                     /gene="amaP"
                     /locus_tag="J8S10_002518"
     CDS             9076..9639
                     /gene="amaP"
                     /locus_tag="J8S10_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HAZ9631082.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            9653..9841
                     /locus_tag="J8S10_002519"
     CDS             9653..9841
                     /locus_tag="J8S10_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HAZ9631083.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            9854..10756
                     /locus_tag="J8S10_002520"
     CDS             9854..10756
                     /locus_tag="J8S10_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAZ9631084.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            10788..11030
                     /locus_tag="J8S10_002521"
     CDS             10788..11030
                     /locus_tag="J8S10_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAZ9631085.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(11286..11657)
                     /locus_tag="J8S10_002522"
     CDS             complement(11286..11657)
                     /locus_tag="J8S10_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631086.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
BASE COUNT         4180 a         1985 c         2232 g         3390 t
ORIGIN      
        1 aaaaattcat tggtcgttga atgggctgaa tagtagtgta taaaacaatt ttgtggagcg
       61 tgaagctttt atggtagagg aaaatacgaa taaagtgatg ttgataaaaa gattcctatc
      121 ttgaatatga atcgagatgt cttgaaaatg aatgagtttg accaatcatt atcctatcga
      181 aatttacagt ttcgttcgat tggtctgtca attaatgaaa aagtaaaaaa gaatatgttc
      241 taggaagagg gcggcacatc taaattttta agtaacggac agttcaaata tcaagcattg
      301 aaagaggcta tcctactgtt tgaaggaata cgaatatata aaaacgacaa agaggaaaaa
      361 gtagttcatt aaatcccttc aagtgatgaa agaatgagat ctaataaaac ctgatctttc
      421 atctgttttt ttaataacgt aataattttt ttattttttg tgctttcgcc gttattgtag
      481 agtgatttag cattcttatt tttaaaaata actgtgttat atattaaaaa aggcataata
      541 gttataagct tttttaaaga atatttagaa attattaatt ttcgtctgaa aacaaaaaaa
      601 gaaagcgtta ttattttagt ctattttcag ggggggaacc ttatgataaa aaaactattt
      661 ttactatcaa tattaacgct agcaatggca ggttgttctg actctggctt agcaactgaa
      721 ctgatcacaa aatcaactga agccacgaca gaggagttaa aatgtggaaa cgatcacagt
      781 gactacagag gcttaaatcg acgatgcatg ggaatattag gcagaagcaa ttgtaagcat
      841 cgatgtagta atcgaagaag gtgtagaaga agcaacagaa aaatcaaaag aaagatcaaa
      901 agaagcaatc tgtgctgtgc atcgtataca gacgtcgaag atgcggtact tttaaaccac
      961 gtcaggagat gttcatttat gtctagggaa gttggcgatg aaccaaaact agagtacgct
     1021 tttagttttg cacgtgagga tgaagataac cctaaaactt acgacatttt agcttgatct
     1081 aagatggtta aagcttttta atgaagtaag aggagataga aggcttttct agttatatta
     1141 ggtaagataa attccttttt gctccaaatt tgctaaacat tctgctagat aaacttcatc
     1201 gtgttccgga taaatcggca cgttgcgctc tacagtaggt aaatcaaaaa atgcttcgca
     1261 tgatttgcca cgatacatag gatttttcca ctctggtgct gggctgtaac cacgtttttc
     1321 catttcatcc atgacaagct gatgatattg gaataatcta taaggagaat agtgaaaaac
     1381 ataatccaca gtagcatgtt tctttcccca gccatttcct cttaatgcac agcattcccg
     1441 atgttgtcct aaaagctgtt gacgaggaag ctttgaaatc aatttttcat gccataatcg
     1501 catagaaatg tctcctttat atatagattg ttaaccttag acgttaaatg aaaaaaccag
     1561 caccaaggct ggaaaaaatc acttcagttt gcttgctgtt tctgagcgac caattaggta
     1621 atcaacggaa atatcgtaaa agtcagcgat atagattaat tcaatgatgc ttggaatttc
     1681 ttctccttct tcgtacttac gatatttgaa taaaggaata cttaacgcgc tagaaacagc
     1741 tacttgagat aaagatcggc cagttcttaa gaaattcaga cgacaacgta aagtatccag
     1801 taaaatagct tcttcgatac tcatttaatc acctttcatt atagtagaat agttataatg
     1861 actatagaaa gctacacatg caatcaatag tactcaatgt tttttattta aacgtatcaa
     1921 ataaagaatg acgatcaata aagacaaaac cagtcctgat aattcttcta taaaaacact
     1981 atcgggttca aagtagttgt aattaaaaac tttccacata aagtagatag ccggaagagt
     2041 caaaatagct aaataaaacc gttctttgtt ccaattcata agataaacaa tacttgcgac
     2101 cagtgcgacc gcaggcaccc aaaacaaaac tctcaccaac gtaatcatgt aacggactcc
     2161 tcaacgattc atataataaa agataacatg ttattgcata catcacaaat gaaatgctag
     2221 gaaaataaaa gaagaataga tcaatgaaaa atgaaaaagc agaacagttt tctgctgata
     2281 agcaggaact gttccgctga atgtgtctta tctatcgaga aaaaatcaat ggattgatat
     2341 ctaagtaatt caatacatat aaaaagagga cgatcgcatt cactaaaaag gaaagaatga
     2401 tgatcccata gcgaatggaa acatatttaa caaatacttt tgtttgaata cgggcatatc
     2461 tttttccttt atagctgagc atcatgacaa gaagcaaaag ggtaatcaca ccttgaaaaa
     2521 tcattccaat aaacagaatt cctgaggttt gataatttaa ttggagaaaa taagctgctg
     2581 ccgcaactaa atcgaataaa atcgcaataa atggcaaaat aatcactcct aacattgaga
     2641 ataaataaaa gaataacatt ttttctaaaa taagcaaata aaaattaaag taacaaaata
     2701 gttatgacac aagtaaaaga aataagaata acaatattat tttacttata ttttgaaact
     2761 tgtgagagtt tgtcattcgt gctatagttg aaaagtaaca aaaataaatt ttatttatga
     2821 tgtaccttta gctcagttgg ttagagcaga cggctcataa ccgtccggtc gtaggttcga
     2881 gtcctacaag gtacataaga ggttgtgaaa aagctgccct gcatcaagta ataagaacag
     2941 ccaagtaaaa acagcttctt atgtttttac ttggctgttc ttattactgc agatgcaagc
     3001 ttttgaatac cgtttaagga agaggttgtg aaatcagcgt tttgacctga gtattagctt
     3061 aacaaacgga aaaatagttc ctcatatttt gccgtttgtt aagctaatac cgagggtcag
     3121 ctgattgaac accatttaag aaagaggtcg tgagcctgcc gtttcactct gtgtcataaa
     3181 aaagccaatc tactttgata gaaaaagcac gtaggactaa aacagttctg cgtgcttttt
     3241 ttattgtgtg ttaaatatcg taaatgaaga tagatatttt tatgattcga cgatagagac
     3301 gttgaaatct ttcaacagct ctaaagcgga ttctccgtgt tttctactgg agactaacat
     3361 tggatcaaca aaaaagtctg cttcaggaaa agcactctgc aggcctatca gattagagag
     3421 tacacacaag tttgtttcaa tcccgactac ttcgatctct ttttgttctt ctttgctttc
     3481 aaataaagtt tcctggattt cagctaaagt ttcaggtgga atcgtaaagt aatacttttt
     3541 aatcactcgt tcattttctt gtggagaaag aagagggatc aattgcaaat cttctcgttc
     3601 ttcttctttg tccttcagtt caactggtat atcccgtgtg aagagaatat attcattatt
     3661 ttggcgtgct ttagctaatc tttgagcaat acgttctgcc aattgatctg actctggaat
     3721 ataaaattcg ctgtttggat caagaatatg attttgcata tcaataataa ctaacatttt
     3781 ctttcctcct acattcatat cgtcatttta ttctttttaa tagaagtttt ttaaaatata
     3841 agcaacacca gcttcttcat tcgtcagtgt tacttggttt gcaatttctt ttacttgtcg
     3901 ctgtgcattc cccatcgcaa tactcaaccc gctgtaattc aacatagcaa tgtcgttttc
     3961 ttgatcgcca aaagccatga tgtcactcga ttcgattcca aggtaatccg ccagaaaaac
     4021 aagtgaatga gctttagtga tacctgtagg cgtgatttct aagaaatgcg gatcagagaa
     4081 tactgattgg ataccatctg cttgcagatc tctttgtagc ttctgtagtt tttcttcact
     4141 cttatctgtt aatgctaatt taagatagct aagagaagga tcttccaaca tatttaaaat
     4201 ttgatcaaaa gaatggttct gtaaattgaa atgttcataa taagggtcat ctttgactag
     4261 atttgattca tcgaatgtca gctgatcatc ttgggtttct cggctagcaa tgatggatat
     4321 tttcgcttct tgagcataga agaaggcttt tctcagtgta tcgctatcta tttttgaacg
     4381 tctgagaact ttcgccattt ttccatcctt catttcagca atcagtgaac cattggaaga
     4441 aatcaaatag ccaccgattc ctaattcgga aaaaatatct ttagcagaaa tgctgttcct
     4501 tccggtagcg acggttacga ttccgccatt ttcatcaaat ttccgaagtg cttggatatt
     4561 ttcttctggt atctttccat ttcgatcaag caaggtaccg tctaaatcaa tcgctgctag
     4621 tttcatttta tcttcctact ttctttttac atatctattt tcctgttacc ttaagattaa
     4681 atgagaattt aaaaaaatga aactaacttg ctttgtcatt atgaattttt tcaaaaaaca
     4741 ttcttaagaa aaaggtggct atatatagta gtttttggtc aatacctttg aataaaaagc
     4801 catgaaaaac gaatagttag cgcttaccga tgcgttttgt gataaaaaaa ttttaaaata
     4861 ttcaatgaaa acaaagcata tattttgctt taaaaccaaa tgaggaatat tctagatgta
     4921 gaacaggtta gaaaaagatt agaaaaagga gtgattttga tggagaagag atacggcgta
     4981 gttcctgtgg taactgcttc agacgaaaat tatgctcctt acttgagcgt gatgatcgca
     5041 actgcattag aaaattgcaa taaaacaaga cgcataaaat tttatgtgat tgacgatggt
     5101 ctatcagaat atagtaaaga aggattggaa gaaacggtaa ataaatattc aagtaatgca
     5161 agtatccaat tcctgacagt ggaaaaagat atctacgaag acttcctagt cagtgaccat
     5221 atcacaacta ccgcttactt aagaatttct ttaccaaact tattagctaa agaggattat
     5281 aagaaagtcc tttacttaga ttcagatgtg ttagtactag acgatatcgt aaaactatat
     5341 gatgagccgt taaatggaaa aacaatcggc gctattatcg atccaggcca agtgaaagct
     5401 ttggaaagat taggaatcga ttccgatgac ttgtacttca attcaggagt gatggtgatt
     5461 gacattgatc aatggaataa aaaagaaatt acagaaaaaa ctatccatta cctcagtgaa
     5521 aatggcgatc gaatcatcta tcacgaccaa gatgctttga atgctgtact ttatgaagat
     5581 tgggaacaac ttcatccaaa atggaacatg cagacttcgc tgatttttga acgtcatcca
     5641 gcaccaaatg aaaaatatga acgtcagtat aaagaaggaa atgaaaaacc ttcgatcgtt
     5701 cactttacag gacatgataa accttggaat acgttgaaag atcatccgta taccaattta
     5761 tacttaaaaa aattagcaca cagtactcta acgaaagtag gcgagatcaa tgaataaaaa
     5821 agaaatagca gtagtcgcaa gttgtaacac aaaattcgta ccacatttag ctgcattatt
     5881 tgtctcagta ttagataatt gcaacccgtc taaatttgtt cggttctatg tgattgacga
     5941 tgatatcgat tttgaaagta aacagctttt acgcttctca gtgaaaaacg cacgaatgaa
     6001 ctcagatgtg gaattcttga aaatcaataa agaattcttt acaaatgtgg taatcagcga
     6061 tcgtattcca gaaacagctt attatcgtat tgcgattccg gaattgttcc gcggcacaga
     6121 agttgaacgt atcttatata tggattgcga catgatcgct ttacaagata tctctaaatt
     6181 atggcgtctt gacttcggtg attcaatcgt agcagctgtt gaagacgctg ggttccatca
     6241 acgactggaa aaaatgaaaa tttcagctaa atcaatgcgt tatttcaact caggtttgat
     6301 gctgatcaat gtgaaaaaat ggttagatga aaatattacg caaaaagtat tagatttcat
     6361 cgaacataat ccagaaaaat tacgattcca tgaccaagat gcattaaatg ctatcttaca
     6421 tgaccgttgg ttaccacttc atccgcgttg gaatgcacaa ggctatatca tggcaaaagc
     6481 aaaaaaacat ccaacagcag caggtgaacg tgaatacgaa gaaactcgca acaatcctta
     6541 cattatccat ttttcaggac atgtgaaacc gtggagcaag gattttgaag ggccaacgaa
     6601 gaaatattac gaaaaatatg cagggatgac ggctttccgt tgtgtagcta aattccctaa
     6661 atatccaaaa tatgcaaaag ttcaaccaaa aacagatgta gttgttaaat aatagaagac
     6721 aacaactgaa gagggggagt aggaatggaa attacaatgt ctaaaaatgc agtagagacg
     6781 ttaattgaaa aggttgggga aaatacaaaa atcgcactcg cgcttatcaa tgattccgat
     6841 ccatttctaa gggacaaagg tgcttttgca aaaggcagct tttttcaaat cattcctttt
     6901 gtttcggaat ttggagaata tgcgactaaa atcgagcatc cattattgga catctataca
     6961 tctaaattag agcaaaatta tttcggtaaa cgattgaaca tggacttcaa caaacagctt
     7021 gacagctttt cattagaaaa tgaaatcgca gtactcgatt ataatatcaa attaaagaac
     7081 tgcttcttca gctaatagtt tcgagaaagt ccaaaaagga ggtatacatt gagatactac
     7141 tttgtggatg aagaaaagaa tgtaatagaa acagatgaaa aaaaatataa ttggctcgta
     7201 cttgatagtg caaagcccga agagattgag caagcaatcg aagaattcga gcttcctgat
     7261 gatattttcg taggaaccga atatccggaa gaagtttctc ggatggagcg cctttatgag
     7321 acgaaactag agcatccatt ttctttggta gtgattaatc tagatcagtc agataatcgt
     7381 atcgaaaaaa aattaacgcc aatatctttt gtactttccg ataatctctt gattacttgt
     7441 atcgatagaa aaaccgaatt tgtggatcgg ctgctgacaa agcatggaaa tcatttaaac
     7501 tcgtttgaaa agatcatcac gtatacatta ttagatattt acacccatta cgtgaaagaa
     7561 ctaagagaga tgaaaaagcg aattgacgct ttggataaag cagctcgtaa aacaacggaa
     7621 aatgaagaac tgtataaaca ggcagatctt gaaagagaca tcgtatatat cgatcatacc
     7681 ttaagagatc aacgggaaac aatggatcaa ttatggaatt ctgaaacttt catcaaacgt
     7741 ttagacgatg aacagctact ctatgatgtc catttgagac agcgacaaac agaaaaaatg
     7801 atcgagatct atcgagattt attagagagt attggtgatc tattcaacgg gatgatggac
     7861 aataatctaa atcatatcat gaaatatcta gattcagctg cattaatcat ttccgttccg
     7921 gcgttgttcg cagggatttg gggaatgaat acaggaggat taccgggtaa aagttctgct
     7981 ctaggcttta tactcgtagt ctttggctct ttgatagcag cagtagtttt aggttaccat
     8041 ttataccgga aagattatac aaattaaaga atctatttaa aacaggtatc aaacaaagaa
     8101 atttgttttg gcaatacaat ttaaaaacta ggaggaatac agcaatgaca gaaccaaaat
     8161 taatcgaccc gcgaaacttg taccatacgg agaaatttcc taaacaagat caggatacac
     8221 cagctttaca gcagaatatg attcctgttc ctgattgtgg agaagaatcc tatgaaggca
     8281 ataatcaact agaaaaccgc cgtgtactaa tcactggtgg agattcaggg atcggtcgtg
     8341 cagcagcgat tgcatttgct agagaagggg cagatatcgc tcttcaattc ttcccaggag
     8401 aagaaaaaga tgcagaggaa gtagcaaaat acgtgaaagt tgcaggacgt aagattgtct
     8461 tactaccttt tgatcttcgt gacgaacaag cacctaaaga aatcatagat aaagccgtga
     8521 gtgaacttgg cgggctagat acgatggtac taaacgcagg acagcaaatt tcttgtcagt
     8581 ctattgctga gttaccactt gagcaagtca aagacacatt tatgataaac atcatcgcta
     8641 tgtttgcttt agtgaaagaa gctgttccgc atatcccagc aggaggagca atcgtaacaa
     8701 caacttctgt tcaagcattc aatccaagcg aacatttatt agattacgca gcaacaaaag
     8761 cttcaatcgc taactttacg atcggtttag caaaacagct tgcacctaaa ggaatccgtg
     8821 taaatggtgt agcacctggt ccaatctgga caccattaca actagacgaa ggacaacctt
     8881 ctgattcgat ccctgaattt ggtcagcaaa gtttactaga acgtgcaggt cagccaggag
     8941 aattagcacc agtttatgtt ttcttagcat cgaataaagc aagttatgtt acagcccaaa
     9001 tttacggagt aactggtgga gaagcgatca acttataaga agttgatcgt ttcaccccta
     9061 tgaggaggtg cgaaaatgaa taaaggtgta aaaacgatcg gagtgatcgg aacattactt
     9121 ttgctatctg tgcttttgtt tgcgatacta ttaagtgcaa cctatccatt gccttttcag
     9181 ctagagaagt ttcgattctt ttccatcact aattcatacg tgcaacaata tgtattttgg
     9241 cttgccgttg catttgctat tttgacaatt atcacgttac ttgttttcct gttttatcca
     9301 aaaacaatcg gaaactttct actgaaacat ggtgatgggg agttgacgtt ggataaaaaa
     9361 gcaattgaag gaatggttcg ttctcacttg catgaagatg aattcatcca ttcaccaaaa
     9421 gtaaatgtca aagcaacgaa aaacaagatc gccgtcaatg taaaagggga gttgaaacga
     9481 acttcagcac tcattggtaa aacaggaaca ttgatgaaag aaatcgaaaa tgaagtacaa
     9541 cacatattgg gaacaaaaga gccagtgaaa gtatcggtga aatacacagg ctttgaagaa
     9601 ccagctaaac gaagcaatga ccgcaaacga gtagaatagg gggggaccaa aaatgaaaga
     9661 actattttcg acatacaagc tccctatcat ctttggggta cttggattga tattagccgt
     9721 tttatggatc accgtgggct ttttcaagac cttattgatc ttgatcatgg cagcgatcgg
     9781 cgtcgctatc ggtttttatc tgaaacaaac gaaaatctta gatcactatt ttaaatctta
     9841 ggaggaaaca tccatgaata acaataacaa aaataataac aataaaatga acaaccaaaa
     9901 accagtgtct gcacatccag acccaacgac accaaaccaa tcaaatggtg tgaacgatga
     9961 aaagaacaaa acagcaccag tatctgcaca tccagatcca gtagtcccta acgttcaaca
    10021 aggagtagaa gagaagaaac atgatgcaga aaagcatgca cctcatcatc caggaactcc
    10081 agaatctaaa gttccagaac aacatgatgc aatcgatcct tctaaacctg tggaagagca
    10141 aaaacatcct tctgaccatg cgaaagcaca agaaaaactt agttctgacc acacaaacgg
    10201 acaaggaaaa cttggttctg atcatacaaa taaccaagga aagcatgatt ctgaacagga
    10261 agattcaatg cgcggtgagc tgaattatga agataaagtt gtgcaaaaaa tcatcggaat
    10321 cgcaattgaa caagtagacg gtttattatc tgcaaacggt ggtttcttct ctaatgtggc
    10381 aggaaaactt gtgaatacag ataatgtaac ggctgggatc gaaacagaag tcggtaaaaa
    10441 acaagtagca gttgatatgg atgtcattgt ggaatatggc aaagatatcg aaaaaatctt
    10501 tgaagaaatg caagaagtaa tcggcaaaga agtaaaaaat atgacacatt tagaagtgat
    10561 cgaagtcaac gctaacgtag tggacatcaa aacaaaagaa gaatttgaaa aagatcaaga
    10621 aacggtgcaa gacaaagtaa ctgacgcagc gaaaaaaacc ggtgaatttg cttcgaatca
    10681 aacagataaa gtaaaatcag cagctggaag cggcgcacaa aaagtaaaag aaaatacaga
    10741 accacgggtt cagtaataag gaagtaaaac attaggagga acgaaacatg ggatttattt
    10801 ggtcacttat cgtcggagga attatcggag caattgcagg agcaatcacg aataaaggtt
    10861 cttcgatggg gattattgca aatgtcgtag caggtttagt tggatcagca cttggtcaag
    10921 cattattagg ttcttgggga ccaagtattg caggaatggc aatcgtgcca tcattgattg
    10981 gtgccatcat tttagtacta atcgtatcat tctttgctcg aaaactgtaa aaagactttt
    11041 aaaaagaggt cgtgaaaaag ctgttcttca tcaagtaata agaacagcca aacaaaaata
    11101 gcttctcata tttttcattt ggttgggcat attatcgaag atgcaagctt ttgaacactg
    11161 tttatacgga ataagaggct gtgacaagac ttttgtcaca gcctcttatt tatgcgggca
    11221 aattcccaat tagattttta aaagtttttc cttaaatgtg tctttattga tacagagaag
    11281 cttctttaat aaaacaatgc ctccctaaat tttcttgaga taggaaaggt gaacatacaa
    11341 aataatacga ccactttgaa aacccagatg atccacaaat ggatcgtatg atactgatga
    11401 agtaaaaagc aatggatcag aaactcaaag agattgaaaa agacaaggaa gaaataatat
    11461 ctctttttta ctcttgtctg ttttagccaa taatagctcg taaagtaatc tagacaaaca
    11521 aatagaagta aacaaagttt cgtaagagca gcaatcgtat catgttgctc tgctagacga
    11581 ttgacgagca ggaaaaatgt tggtaatgga atatagatca cgagtaatga aagaaaaaag
    11641 taaacaataa atggcatact attcctccta attgtgtgag ttcgccctca ttttaaaata
    11701 acgatatttg tttgtgaagc tttttcgtgt cgtaacaaat gttatctaat gtatttttaa
    11761 ataaataatc attattatca aaataat
//
LOCUS       DADQDV010000084        11316 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.087, whole genome shotgun sequence.
ACCESSION   DADQDV010000084 DADQDV010000000
VERSION     DADQDV010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11316)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11316)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11316
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.087"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            544..1107
                     /locus_tag="J8S10_002523"
     CDS             544..1107
                     /locus_tag="J8S10_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAZ9631087.1"
                     /translation="MSGYIYGYARVSTRSQELNRQLDLLNEQNCNEILTEKMTGTKAV
                     RPQLNRLKDKIRPGDTVIVESFSRLGRSTKDLIDLVTYFEEHHVKLVSLKENFDTSTP
                     HGRLMMTVFQAFSQFERDLIVERTKEGLKSARARGRKGGRPRVNQKDVDRAVKLYKSQ
                     VYSVKEITEMTGISKATLYRYLKDNRE"
     gene            complement(1386..1673)
                     /locus_tag="J8S10_002524"
     CDS             complement(1386..1673)
                     /locus_tag="J8S10_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAZ9631088.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQ
                     KTGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPILLCGTHENFYEQLKKIR"
     gene            complement(1663..1992)
                     /locus_tag="J8S10_002525"
     CDS             complement(1663..1992)
                     /locus_tag="J8S10_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007723369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAZ9631089.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEP
                     KKEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEE
                     LAAEIGL"
     gene            2297..2626
                     /locus_tag="J8S10_002526"
     CDS             2297..2626
                     /locus_tag="J8S10_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAZ9631090.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVF"
     gene            complement(2913..3398)
                     /gene="vanZ"
                     /locus_tag="J8S10_002527"
     CDS             complement(2913..3398)
                     /gene="vanZ"
                     /locus_tag="J8S10_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HAZ9631091.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(3551..4462)
                     /gene="vanY"
                     /locus_tag="J8S10_002528"
     CDS             complement(3551..4462)
                     /gene="vanY"
                     /locus_tag="J8S10_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-A/VanY-F/VanY-M family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HAZ9631092.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYELWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            complement(4890..5498)
                     /locus_tag="J8S10_002529"
     CDS             complement(4890..5498)
                     /locus_tag="J8S10_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HAZ9631093.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            complement(5504..6535)
                     /gene="vanA"
                     /locus_tag="J8S10_002530"
     CDS             complement(5504..6535)
                     /gene="vanA"
                     /locus_tag="J8S10_002530"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HAZ9631094.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALAVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            complement(6528..7496)
                     /locus_tag="J8S10_002531"
     CDS             complement(6528..7496)
                     /locus_tag="J8S10_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HAZ9631095.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            7828..9120
                     /locus_tag="J8S10_002532"
     CDS             7828..9120
                     /locus_tag="J8S10_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAZ9631096.1"
                     /translation="MSYTHLIKETLDILDLSVTFNENCLTKEKYKGQICHIYRGNLIY
                     TAQECIHCKHQIASDIVRWGTTTVRLLMNDVSEYRTYLELKKQRFKCKACQRTFVADT
                     SVAKKHCFISEKVRWSVVTRLKKNTSMTEIAAQKNLSVSSVYRIMKRFYRPLNPFRTP
                     LPKVLCFDEFKSVRGVSGAMSFIMMDGQTQRLLDIVENRQLPFLKRYFSHFSREIREA
                     VEWIVIDMYAPYVSLVKKLFPKAQLIIDRFHIVQHIGRTFRNHRIKETNQLLKSKEQK
                     HYQLGKQLKRYWKLLQKDERKLDYTRRLWRPGFKAHLTETDIVDRLLKGSPALRVGYQ
                     LYQDFLYAVKERDYVSFEELLTNNIMLPEGYQTTLRTFQKFLPQIKNALQQSYSNGPL
                     ECLNNHIKVLKRNAYGFRSFYNFKLRIMIRHGNALIFN"
     gene            complement(9218..10372)
                     /locus_tag="J8S10_002533"
     CDS             complement(9218..10372)
                     /locus_tag="J8S10_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HAZ9631097.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
     gene            complement(10350..11045)
                     /gene="vanR"
                     /locus_tag="J8S10_002534"
     CDS             complement(10350..11045)
                     /gene="vanR"
                     /locus_tag="J8S10_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HAZ9631098.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
BASE COUNT         3398 a         2288 c         1946 g         3684 t
ORIGIN      
        1 ttaaaacttt tttagcagat tttaaagttt cgtcaaaact aatatattct ggtagctgag
       61 cattcaaata gctttcagac ttcagaagaa aattacgagc atttttatag tccatctcta
      121 ataaagttat tcttttttta tccaatacat tcagctcaat tccttataat attctattcc
      181 ttagtatctc aacattattt actttataaa acgaataaat tttgtagttc taattcaaat
      241 attgcatgtt atatctaata tgggagcatt ttataatttt cattgtgata aactcgttat
      301 taactttagg atacactagt taggattaaa ttaggtatct agaaatttac ttaagatttt
      361 tttgtttatt tcgtatacac actcgtatca aaaacaatcg attatgagac aaaatgaaat
      421 gacctctttt attaaataaa agaggtcata ttttgtatca taacttgttg cattaactat
      481 gtatctataa ctccctttta tgatacaatc aagccagaat taaagtacga aaggaagaaa
      541 agcatgagtg gatacattta tggttatgcc cgagtgagta cacgttcaca agaactaaat
      601 cgtcaattag acttactcaa tgaacaaaat tgtaatgaaa tcctaactga gaaaatgacg
      661 ggaaccaaag cggttcgtcc ccaactaaat cgtttaaaag ataaaattcg tccgggagat
      721 acggtaattg tagaaagttt ttctcgattg ggtcgtagta caaaggattt gattgacctt
      781 gttacctatt ttgaagaaca ccatgttaag ctggtgagct tgaaagaaaa cttcgatacc
      841 agcacgcctc acggacgctt aatgatgact gtcttccaag catttagtca gttcgaacgt
      901 gatttaattg ttgaacgtac caaagaaggt ttgaaaagtg cacgtgcgag aggtcgtaaa
      961 ggtggccgtc cacgagtgaa ccagaaagat gttgatcgag cagtaaaatt gtataaaagt
     1021 caggtttata gcgtaaaaga aattacggaa atgactggta ttagcaaggc aacactctac
     1081 cgctacttaa aagacaatag ggaataatct attttaatct ttaggaatct ataatattta
     1141 tgggagaatt agagtgattt ttttattatt actaaaaaac aatataaaat aacgcatttt
     1201 aagccctctt tgtgcataag gatgaagctt ttaatttgaa agaggcttaa aatgcgtttt
     1261 aattttttct atttttcata aatatatagg ttagtggttt aaaattatag ggtattacaa
     1321 ctctcagctg ttaaaaatta tcttttaaag tgtcgtctat cctctcaagt tgaaacattg
     1381 ggttcttacc taatcttttt taattgttca taaaaatttt catgcgttcc acatagtaag
     1441 ataggtatca ctgcattatc tttaatttca tatgcaacgc gatatgtcgt acctgcatac
     1501 ttgaatccaa tagcccaaat tcctgataaa tcacccgttt tttgttctcc cgaatgagga
     1561 cgaactgcta tctcatcata aattatcgtt aaaaattgtt cttttaatgt tttctctttt
     1621 aattttttta gatactttat tacgtgttta gaaggtagaa tctcataagc caatttctgc
     1681 tgccaactcc tcttttgtca tcggtttaga atttgcaaca gtatcttcag caatagattt
     1741 aaatgcagaa gttaacgcat tttttctatt tctaaattct tttaagatct cttgtttgct
     1801 ataaccttct gaaagaatat cagccaaaat atcttcacta aaatcaaaaa attctttttt
     1861 aggctctaca aactcataaa ggataccatt ctctacaagc ttagcttcta cttcaacacc
     1921 attgggcaca tcgaattctt tagggaccgt taacataata gaatttcctt gttttcttgt
     1981 ttttgtaatc atattatttc ctccattatt ttacatttcg taattactta gtaattacat
     2041 tgtacgctat ttttagtaga aatacaaaat aataaaactc ctttagaaca attttcaaag
     2101 gagttttatt tgattaggaa attatgtaga ataataatat gtttttaact tggaatcaaa
     2161 aacgcacttg caagtaagtt tacttcaata catgaaattg cttataatag tgtattggaa
     2221 ttaaggtaga ttgacaaaag agtgatcaaa taggtatact tcattcaaat aatcgtttga
     2281 atgtgaggtg agatgaatga aaaaagtttg ccaagtgact gtcgtacata aagaaaaagt
     2341 aaatggaata aaaaataaat tggatcaaaa agatttttca aacttacttg tgttagggaa
     2401 atgtttcagc gatttttcta gaattaaaat tttctatgct ttagaaacct ataaggaaat
     2461 gtgcgtctgt gatttagcag aaatacttac tgctagtgtc gctacaacgt cacaccattt
     2521 acgtttttta aaaaaacatg gaatggcaaa atcacgtcaa gatggaaaag tagtttatta
     2581 ctctttagcg aatgaagaca tcctttccgc tattcgtgtt ttttaaagtt atcagaaaat
     2641 ctatctatga aatcttagtt tgggggtacc gtcaggaaaa tgcggattta caacgttaag
     2701 gaaatttatt aaagagacca attcctcagc actaaaattg ataattgggc tttctttgtt
     2761 actatagtgt taggtaagct ttttacttta tcaccggttt tcccctcact tcacacctac
     2821 gggcgagttt ccccacatcc cgttttccat ctaatccaat tcattcaata tctttatgtg
     2881 tatgaaagat cagattgctt gatttagaca tcttacacgt aatttattct taaatgggta
     2941 cggtaaacga gcaataatac gagcaaaagt atacctacaa aaataataac tctgtctaat
     3001 tttttttgat tcatatgctt attgcttaaa ccatataatt tcagtccaag aaagcctcca
     3061 acagtatttg taattacatc tgttatgtct gtcgctccaa tagcgaagat aaattgaatt
     3121 atttcaaaag taagacttaa aaccagtaca aaagcaaact taggtaaaaa tccgatttct
     3181 ttaaaattga cattcaaaag caagccaaat ggaataaaga ttataacatt atctatcatc
     3241 tctctgaaat tcccagtagc agtaaatgga gtcaagttaa gacttctttg atgataatta
     3301 aatactgata aaatattgta ttgtaatttg aataacacta accagattag tgtcactaaa
     3361 tataaagcta gcaatcctct agataatatt tttcccaata taatttcctc taattctttt
     3421 gtttaagttg tatcattagt atagcaatgt cctagttaac gtgggtttta aattaaaaag
     3481 ctaacgttac cccaaaagtg ctagtacaat aatgctgttc attaatttcg ttggtttcat
     3541 tccgccatcc ttacctcctt gaattagtat gtgttgatcc gggaaacact gtcacaatta
     3601 caccgtctat attgtttcct gatatctcat aacgaagatt agtcggcaca tgaatggtgg
     3661 tatttttagt aacaggataa taaaagatct catatttttc cccatttaca ctaacagaaa
     3721 tggttttttc ttcttttagg taatccatat attcctcgag aacgaaattc ttttctttca
     3781 taatcgcact atgtggtaaa ccaacatagc gaatatgcca tagttcatat tgaattcctg
     3841 ttaactctgt tttgtcctct ggataacgta aaatgaaccc gtatttccaa gcattttctt
     3901 ctatccactt tccttcaggg gctcgttcca ttttcgtcaa gcttgatcct acatctagtg
     3961 ataaacctga attatgctca ctataacctg ctggtaaggc atactcagcc cccatttctt
     4021 ggtaaagcac actttgctca tcaaagtctc gatagccact attaataata aaatgactaa
     4081 cgccaccctt tacagcatca ttgaccatct ctgaaaattt ttgtgctatt tcttttgaca
     4141 tataaatatt actatcaagc aacccgtatc catttattaa ttcgtcatgt ttagataaat
     4201 tcacgatatc tgacttcaca ctttcttggc gaacaggata tttactattg attaatagca
     4261 gatttccttg ataaacctgt tcttctgtaa ttgttttctc ttgggtattt tcagaagtcc
     4321 cactattttc taaatgttct ttgggatttt gatcataatt ttgaaattcg actttttcct
     4381 gagaaaacag tgcttcatta acgtagtcat aacctaagta tattaagaat aacaataaca
     4441 ataaaaaaaa caacttcttc attttcagtc tcctccttaa ctatatagtt ggaagtatga
     4501 aatatttcta gaatcttccc cttaaacggc acaatctcgt ttgagattgt gccgttttgc
     4561 cccgtaaatt acagtcaatt atttcgccct actggattta ctattatcac caatgtagat
     4621 gaattttcat aagtgatacc catgctgaat ttaacgaggc tgaactgcct gttgacaatg
     4681 ggcggtgtga aataccaccc ctctatgcga tcagtcttat tatcaggcta tcttgccgca
     4741 gcgcacgcag ataatgaccg caatatcgct ctgccttaca tcttcaatac tatctactat
     4801 atataaattc cctaagaacc agttacatac gtcgggtttc ctgccgaaag agttagctta
     4861 tatagtttgt ccgtgcaacg gttaaaagtt tatttaacgg ggaaatcaaa atagctattg
     4921 gggtatggtt cgtctcttaa tacatagtgc caccattcga ggctatatgc ttcaaaccca
     4981 ctgttttcca tgatggagcg caaacgtctg cgattttgcg cttcattgca tgatattcca
     5041 tttgccgcat gatgagagcg ttcatccata aaatcaaatc ggctccccat tggtacaagc
     5101 tcacccgtgt ctaatcgata aagcgtaaga tcaatggcac tgccgcggct atggcttgat
     5161 tttgaagcca cgtatccttt tgaaatcatc tcagttcggt caatattggg ataataactt
     5221 tcctttgtca ggttattttc cggctgtgca gcccattgca taaaacagtt tacagcacga
     5281 ttaggacggt aaccgtccca tagaagcaat ccgtaccctt gggtagcagc cagttctttt
     5341 gccttcaaaa gcgattcagc caactcgtat gtccctacaa tgcgatttac ttcataaccg
     5401 tcaaccggtt ttccggtgaa attatcccaa gtggcatatt tagcgtccca acgaacaccg
     5461 tgtactattt catctaaaaa agtaaatcct atttccatgc ttatcacccc tttaacgcta
     5521 atacgatcaa gcggtcaatc agttcgggaa gtgcaatacc tgcagcggcc atcatacggg
     5581 gataacgact gtatgacgtg aaaccgggca gagtattgac ttcgttcagt acaatgcggc
     5641 cgttatcttg taaaaacata tccacacggg ctagacctct acagccgagc gctttatata
     5701 ttttttttgc cgtttcctgt atccgtcctc gctcctctgc tgaaaggtct gcgggaacgg
     5761 ttataactgc gttttcagag cctttttccg gctcgacttc ctgatgaata cgaaagattc
     5821 cgtactgcag cctgatttgg tccacctcgc caacagctaa cgcggcactg tttcccaata
     5881 ccgcacaacc gacctcacag cccgaaacag cctgctcaat taagattttg ctgtcatatt
     5941 gtcttgccga ttcaattgcg tagtccaatt cgtccgcgct attgactttt ttcacaccga
     6001 aggatgagcc tgaacgcgcc ggcttaacaa aaacaggata ggtaaacgta gctgccaccg
     6061 gcctatcatc tttattaata acccaaaagg cgggagtagc tatcccagca tttttcgcaa
     6121 cgatgtatgt caacgatttg tccatacaaa ttgctgagct ttgaatatcg cagcctacaa
     6181 aagggatacc ggacaattca aacagacctt gtatggatcc atcttcacct gacttgccat
     6241 gcaaagctga aaatgctaca tcaacatggt tgatttcata ttcatggttc tttttaacaa
     6301 gtaatccgtg cattttttta tccggcgaga gtacagctga atagcaattg tcgttttccc
     6361 attccgcgca aggtttttcg cacattttcc atacaccaga tttcgtaatt ccaatgtata
     6421 acggctcgta tttttcttta ttaatgttag cggctatctc tattgcagat tttaccgata
     6481 cgtcatgctc ctctgagcaa cccccaaaca gtattgcaac ttttattcta ttcatgctcc
     6541 tgtctccttt caaaatccaa acagttttta atggtttttt caacggtatc acgcaacgct
     6601 tgctcggtat aataggccgt atgcggtgtg attatcacgt taggcattct ttgaagttta
     6661 agtaaaaatt gattatcaat tggtttttgg gtgcaatcag agtagaaaaa ctcttcctct
     6721 ccttccaata catccaatgc ggcaccgccc agtttcccgt tttctaatgc tttaaccaac
     6781 tcataggtat ctacaagtgg accgcgccca gtattgataa gaaatgctcc ttgcttcatt
     6841 ctctgtattt gttcgtggct gataatatag tgcgtatccg tattgagcgg cacatgaagc
     6901 gtaacgatat cgctattttg cagcaactca tcaaacggta catagtttac ctctatactt
     6961 cggctgcgac tataagccaa cactttacat ccaaatcctc gcagccgctc aataaccgct
     7021 ttgcctatct ggcccgttcc caccacacca actgtcatgt cgctgagtac cttgccacgg
     7081 tcgctgtcca acctgaaatc atgtttttcc acagagcgca caatcgattt tacgttgcgt
     7141 actgccataa gaattagcat catagtataa tcggcaacgc tatccggcga gtacgccaca
     7201 ttgtcgacag tgatgcccat tctcttagca gcagttgtat ctatatgatt gcagccgatg
     7261 cttcgggtag aaatatattt cacaccggct ctcttcagcg caagaagaat agaggcggaa
     7321 atctctgatt tatgtcccac actgatacat tgattgaaag gcgcggattt ggcgttggat
     7381 tccgacacgt tggcgttaat tatcgttgcc ataacgccaa agcgaggcga aagagcatgg
     7441 aatgcatctg cctcatcctg ctcacatcca taaacagtaa tgccgatgtt attcataatt
     7501 aagaccaacc ctttctgtga aaggcaccaa ataaaacggg gatgccaatg gtaatcttgt
     7561 caaatctttc tctgaagaac gaaaacggct cgttcttacg gtattaagtc taccgtgtaa
     7621 gaacgagccg tttcttaata ttaaattgtt aatttcctaa gaaaaagtaa agataacctt
     7681 gagattttcc taaaaaatta tggctctata ctttttgatg ttggtggatg acaccagcat
     7741 cttttttatt ttccaaaaca tatagaaaag acaccttgaa atcctttaga attaatttgg
     7801 cgaaccaacc caaaaggagg aatcaagatg tcttacactc accttatcaa agaaacatta
     7861 gatattctag acttatcagt tacttttaac gaaaattgtc tcacaaaaga aaaatacaaa
     7921 gggcaaatct gtcatattta tcgtggaaac ttgatttata cagcccaaga atgcatccac
     7981 tgtaaacacc agattgcttc agatattgtg cgttggggta caacaaccgt ccggttgtta
     8041 atgaacgatg tttctgaata ccgtacctac ctcgaattga aaaagcaacg cttcaaatgc
     8101 aaagcttgtc agcggacctt tgtcgcagat acttctgttg cgaaaaaaca ttgtttcatc
     8161 agtgagaaag tccgctggtc tgtcgtgact cgtctgaaaa aaaatacctc aatgacagag
     8221 atcgccgctc agaaaaatct atcggtctct tctgtttacc gtattatgaa gcgattttat
     8281 cgtccgttga atccttttcg gacaccgtta cctaaggtac tttgttttga tgaattcaaa
     8341 tcagttcggg gtgtttcagg tgctatgagt ttcatcatga tggatggaca aacacagcgc
     8401 ttattggaca ttgtcgagaa ccgacaactg ccttttttaa aacgttattt tagtcatttt
     8461 tcacgagaaa ttcgtgaagc ggtcgaatgg atcgtgattg atatgtacgc tccttatgta
     8521 tcgctcgtta aaaagctgtt tccaaaagca cagctgatta ttgaccggtt tcacatcgtc
     8581 caacatattg gtcgtacctt tcgcaatcat cgaatcaaag aaacgaacca actattaaaa
     8641 agcaaagaac aaaaacacta tcaattaggt aagcaattaa aaagatactg gaaacttctt
     8701 caaaaagatg aacgcaagct tgattatact cgacgccttt ggcgacctgg cttcaaagct
     8761 catttaacag agaccgatat tgtggatcgc ttactgaaag ggagccctgc tttgcgtgta
     8821 ggctatcagt tatatcaaga ctttctttac gctgtaaagg aacgagacta cgtatcgttt
     8881 gaagaactac ttaccaataa tatcatgctt cccgaaggct atcagacgac cttgagaacg
     8941 ttccagaaat ttctgccaca aatcaaaaat gctttacaac aaagttattc aaatggccca
     9001 cttgaatgtc tgaacaacca tatcaaagtg ttaaaacgaa atgcatatgg ctttcgtagc
     9061 ttttataatt tcaaattgcg catcatgatt cgtcatggca acgcattgat tttcaactaa
     9121 aaaagatcaa gaggaactga tccacttgat ctccaattat tctaagattt ctctttacca
     9181 acatcatttg acaaagagcc aaaattatat acatctctta ggacctcctt ttatcaacca
     9241 agtctggcat cgctggaagc tctaccctaa acgtcgtata gttatcattg ctttccgcgt
     9301 aaatctgccc tccatgctga acaataattt cttttgcaat cgccaatcca agtcccgcgc
     9361 cacccgtatc ggaagaacga gcattgtcca gcctatagaa cttttcaaat atggcagcta
     9421 gcttatcttt tgggatgctt ccagtgttct tgaattcgat tgacaccaca tccccggaga
     9481 ggcccgcggt aatgtcaatg atgctgttat cctcactgta tgcagcggcg tttttcaaaa
     9541 tgttgttaaa gactctcgcg agtttatcag ggtcgccgga cacggtcaga tcctcggggg
     9601 cgtgaataac cgcctgtttt ccatgtgcgg aaagctgagg ataaaattca tcggtcatct
     9661 gcaccagcat atagtatagg tctatgtgcg tttttgttag cgttatcgtt tgtaggttat
     9721 accgtgtaat ctcaaaaaac tcgtcgatta gctgttcgag tcgatacgct ttgtccaacg
     9781 tgatatgcac atactttgcc ttttgatcta ccggcatgtc tggagcctcg tcaagcaggc
     9841 tcaaataacc gataatggat gtaaggggcg ttttaatatc gtgcgccaag tacataacaa
     9901 cgtcattttt tctttgttcg gccagctttg catcctgctc tcgcttttcc agagtccgtt
     9961 ttaatgtgtt gagcttttgt tccataacat ccatttccgc agaaagctca atttgtttat
    10021 cttcgttctg aataagtaca tcaatgccgg tatttatctc gtcaaagtat tttgcgaatt
    10081 ttgaaagcat gacgcgacat agaataagaa tactaatgac aatcgccaca taaataaaga
    10141 tatctatatt gttccgtatg gaatattgat ataatttcat cgcgtccagg tgatttaagt
    10201 catatttgtt ttccaaaata cttaagatcc aatccccaag tttccctcgg atcattgaac
    10261 gaatatacaa cacgaataca attgctacca caacaattgc aacgatatac atgtaaagtt
    10321 ttcgttctag tttggaatag tcgttttttt tatttttcaa ttttataacc aaccccccat
    10381 accgttttta tatatttcgg attatcaatg gtgtcgttca ttttttcgcg caaatgccgg
    10441 atatgcacgg tgatggtgtt gttgctcttg ctgaaatatt cgtcgcccca tatctcatga
    10501 aatagcagct cggagctaac cacattcccc ttgttttcac agaggattcg cagtattgaa
    10561 aactcggtgg gagtaaggga taactgcttc tcgttcagat aacactcatg ggtgttaaca
    10621 ttaatgacaa ggccggagtg gacgataaca ttttcgttct gctcctttac tccactgaat
    10681 tttttgtatc ggcgcaactg ggcctttacc cgagcaatta actccagtgg gcgaaagggc
    10741 ttcgttatat aatcatccgc gccgattgtt aaccctgtaa ttttatctac ctctgtatct
    10801 ttcccggtca gcatgataat cggataggtg tgcttgtccc ttattttttg acagatagta
    10861 aggccgcttg tgccgggaag catgatgtcc aatatggcaa ggtcaatctc agacttgtct
    10921 atacattcca atgcttcttt ggcggtatag tatttgaaaa ccgtataatt ctcgtttttt
    10981 aagtataatt caaccaaatc ggcaatttca tgttcatcat ccacaataag tattttatcg
    11041 ctcatagtta tcaccctttc acataagttt gcccttaata atttatcaga ttatagggcc
    11101 gaatttataa gcatttacat aataaatgac taagaatttc ttaagatgat gattcttttt
    11161 ttatcaaagg gcttttcggc atcgctagga ggctgttaat attttatagt ttccttttct
    11221 tctttaaaaa tattgcccat tagcggaata cagaatggct aattattcac ttctgataat
    11281 ttcctgtata atgaagccct agatacatta gtaatt
//
LOCUS       DADQDV010000085        10645 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.088, whole genome shotgun sequence.
ACCESSION   DADQDV010000085 DADQDV010000000
VERSION     DADQDV010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10645)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10645)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10645
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.088"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            23..646
                     /locus_tag="J8S10_002535"
     CDS             23..646
                     /locus_tag="J8S10_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631099.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1096..2145
                     /locus_tag="J8S10_002536"
     CDS             1096..2145
                     /locus_tag="J8S10_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAZ9631100.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2142..3023
                     /locus_tag="J8S10_002537"
     CDS             2142..3023
                     /locus_tag="J8S10_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9631101.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3026..3796
                     /locus_tag="J8S10_002538"
     CDS             3026..3796
                     /locus_tag="J8S10_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAZ9631102.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4075..4929
                     /gene="aroE"
                     /locus_tag="J8S10_002539"
     CDS             4075..4929
                     /gene="aroE"
                     /locus_tag="J8S10_002539"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HAZ9631103.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5107..6270
                     /locus_tag="J8S10_002540"
     CDS             5107..6270
                     /locus_tag="J8S10_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HAZ9631104.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6387..6797
                     /locus_tag="J8S10_002541"
     CDS             6387..6797
                     /locus_tag="J8S10_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAZ9631105.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6971..9199
                     /gene="topB"
                     /locus_tag="J8S10_002542"
     CDS             6971..9199
                     /gene="topB"
                     /locus_tag="J8S10_002542"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAZ9631106.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9337..9654
                     /locus_tag="J8S10_002543"
     CDS             9337..9654
                     /locus_tag="J8S10_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631107.1"
                     /translation="MKKVHSFLNYLMGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAY
                     SPTLILSTLTAGAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQ
                     YFG"
     gene            9814..10050
                     /locus_tag="J8S10_002544"
     CDS             9814..10050
                     /locus_tag="J8S10_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAZ9631108.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            10047..10445
                     /locus_tag="J8S10_002545"
     CDS             10047..10445
                     /locus_tag="J8S10_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HAZ9631109.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
BASE COUNT         3715 a         1773 c         2253 g         2904 t
ORIGIN      
        1 aggagaaaaa gtagaaaaga aggtgtttgt tatttgggaa gtagttaaat cgagagtaca
       61 agaaatgaat gaacatttct cagtgtcatt cgcagaaaat ccaagtaagt attttcgacg
      121 tcttgttttt ctgctcatct tatcattgct gttaacagtt gcaatgtttt tattgccgga
      181 aaaaatccga gaagagcaag taaatagtct cgtttattcg tccataccaa ccagcaaatt
      241 gaaacctttt gattacagca aagctgatca gaaaatcaaa caaagccggg cgatatcggt
      301 gatgttcagc aaaccgaacg ggaaaaccta tcaggacatg cttgatgttt ttaatgatcc
      361 tgagcttatg gaagaattga atcgaccgat cttttattat ccgatcgttt atgatgtaca
      421 tgaactggaa caaaaatata acatacgaac ggatgaagtg acatttattt tctttgatgg
      481 aggaaaagaa gcaaatcgga taactgcggg taagggagga ataactgatt ttgataagga
      541 gttgatccct gaactgaatc gacttccgtt agccaatatc aaacaattag aagaagaatt
      601 ggatagaacg ggagtaactt cccaaaattc cgagattgct aattgagaca ttggcgcgat
      661 gaaacggtgg gtctatatag cgctattttt aattatcaga acaagtgatg tttgatcttc
      721 aaaataacaa ataaaaaatt aaaaaatata gttgacgaaa ttcaaaaatt cgattagact
      781 taaatcaatt cttaaggaaa gggtgacctg taatgaactt atcaaaacgt atttcagcag
      841 aaaacaaaaa aaattggcgc agctggcgta gataagttgt attaatggtg agactttccc
      901 atagatacaa ctttttagag tgcatttcta aagcttgtat ctatgctaga catgaacatt
      961 gactgccgca tagattagaa tctatgcggt tttttgtgta aagacaatga ccgctttggc
     1021 cattgtcttt ttttgtagac tggatacttg cctgattata ataaataaaa agattgactt
     1081 tgcaggagga aaaaaatgaa aaacaaacga ttaataacag ttgtagtaat tattttagtt
     1141 tatttagcag gtgcatttat ttatggaaaa gcctcaggcg aaaaagaaag tacttcgacg
     1201 aaccagacaa aaaaaacaac agttgttggg gtattgcaat acgtgagcca tccggcatta
     1261 gatgagattt atcgaggaat caaagatggt ctgaaagaag aaggattaaa agaaggagaa
     1321 aatcttgaga tcaaatttca aaatggacaa gccgatcaga gcaagctagc cacaatgagt
     1381 caacagctag tacaatctga tccagatgcc ttgattggaa tcgcaacacc tgccgctcaa
     1441 tcattagcaa acacgacttc atcgatccca gttgtgttag gtgctgtaac ggatcctgtg
     1501 ggggctggat tagtcgcttc tttagagaaa cctggtggta atgtaacagg tgtttctgat
     1561 cagccgcctg ttacttcaca aatcaagctt gcttctgatt tgttgccaaa tgcaaaaaaa
     1621 gtcggaatct tgtatgcttc ttcagaggat aattcaaaat accaagtagc acaagcagaa
     1681 gaagctgcaa aaaaagaagg gttagaatca gtaaaatatg cggtgccttc cactaatgag
     1741 attgcacaaa cggttcaagt gatgagccga caagtcgatt ttatctatgt tccattagat
     1801 aataccattg ccaatgcgat gcaaacagtg gtaaaagaag caaacaaagc aaatatcccc
     1861 gtcattccat ctgtggatac aatggtggaa caaggtggac tagcaacaat cgggatcaat
     1921 caatatcaat tagggcttca aagcggtaag atggcggcag aacttgcgag tggaaaagaa
     1981 aaaccggaaa cgacgcctgt ttatacattt gatcaagggg atacagtgat caatcaatct
     2041 caagctgatc gcttaggaat cattgttccc caatcgatga aggaaaaagc caaaatcatt
     2101 acagatgact cgcagcaaga aacatctaag gaggatgaca aatgatcgta tcagctattt
     2161 cacaaggcat gctttgggca atattaggat tagggatttt catgacttat cggatcttag
     2221 actttcctga tatgacgaca gaagggtcct tcccattagg tgctgctgtc tgtgtgacag
     2281 ctattactca tggggtagcg ccgattgtag ctacattatt aggcgtaggt gctggcatga
     2341 tagcaggact cgttacgggg ttactttata caaaaggaaa gataccggtt attttagcag
     2401 ggattttagt gatgtcagga ttgaactcag ttattttgtt tgtgatgcga acaccaaatc
     2461 tttctttatt gaatcatccg attctacaag acagcttcca tcgctttggg ttacctgatt
     2521 actttgacac agtccttctt ggcttcatct ctttgggcat cttgattgct gtactgctat
     2581 tcttcttcaa tacagatttg ggtcaaggct atattgcgac aggagacaac gaaacgatgg
     2641 ctcggtcgtt agggataaaa accgatcgta tgaaaatttt aggtttaact ttgtcgaacg
     2701 gtgtcattgc attatccggt gcgctgattg cccagaacga cggatatgca gatgtaaata
     2761 aagggattgg cgtaatcgtc atcggtcttg cttccatcat catcggtgaa gtgatcttcc
     2821 aagaattgac gctagcagaa agattgattg ctattgttgt cggcagtatc atttatcagc
     2881 tattgatttt agtagtaatc aaactagggt ttgacacgac ttatctgaag ttgttctccg
     2941 ctatcatctt agctatttgt ctgatgatcc cgcaattgaa gaaagcactg aacttaaaaa
     3001 cgggttttga gaaggaggca tagtaatgac tgatatattg acaatcaaaa atggcagaaa
     3061 agtcgtaaac aatggaatga atgaagagaa agtactattg gatgaaatta accttacaat
     3121 cagagaaggg gacttcatca ctgtccttgg cgggaatggt gctggaaaaa gcacactgtt
     3181 caatacgatc gctggtacgc ttcaactcag tcaaggatcg atctctttta aagatcagct
     3241 gatcacaaaa gattcagaag aaaaaagagc acgattcctt tctcgagttt tccaagaccc
     3301 caagatggga acggctcctc ggatgacagt agcagaaaat ttgctacttg cacaaaaaag
     3361 aggtcaaaaa cggaaattcc gtttacgtaa cttgaaaaat caaaaagaag attttttcag
     3421 actatgtcaa gaagtcggta atggcctaga gcaacacttg gatactccag cgggtgaatt
     3481 atctggtggt caacgccaag cattaagctt gctgatggcg acgatcacag ctcctgagtt
     3541 actattatta gatgaacata ctgcagcttt agatcctaaa acagctaaag cattaatgcg
     3601 attaacaaat cagcggatca atgaacaaaa attgacttgt ctcatgatca cgcatcgaat
     3661 ggaagacgcc ttgaaatacg gaaatcgtct gatcgtactc caaaaaggga aaatcgttca
     3721 agatatttct gaaaaagaaa agcaacattt gacaatgggc gaccttttgc agttctttga
     3781 agaagtagtg gattgatttc gacagaaaaa ttcctttcag tagaaggact tgaaaactca
     3841 ttgacatctt cctttgattc atcctatact taaaacaata aacaattaaa catatttggg
     3901 tgttttgtag gatcacgtag tcaatgattt taacaattaa atagaatatt ctttgctctg
     3961 acaagtaaac gatgagaaaa gaatttgcta ctttgccacc tagacgtttc gtactttttc
     4021 gtatcaaacg ctaagtggct ttttttattg aagtaagaac aaaggaggaa taagatgatt
     4081 tctggacaaa ccaaattagc tgggctcttt gctgatccgg cttctcacag tttatcccca
     4141 ttgatgcaca atactgcttt tgaagcaaac aacatcgatg cggtgtattt agctttccaa
     4201 gtaaatccaa tgaatttgaa gcaagcagtc gaaagtattc gaacttttga tatgttaggt
     4261 gtaaatcttt cgatgccgaa taaaacagcg gttattcctt atctggatga ggtaagccag
     4321 gaagcgcaat tgatcggagc agtgaatacg atcgtgcacg aaaagggtcg tttgattggc
     4381 tataataccg atggtgcggg cttcatgcaa tccgtgcaag aagctgggat ttcgatcaaa
     4441 aagaaaaaaa tgactctact gggagctgga ggtgcagcaa aggcagtcac tgttcaagct
     4501 gcgttagacg gcgctgagga aatcgtagtt tataaacgaa acaaccaaac attcgctcaa
     4561 gtaaaagaaa cattcgaaca actcagctat cgaacttctt gtaagataaa agttcgtgac
     4621 tttgccgata cgcatcaatt aagaaaagac ttgaaagaaa gctgtcttct agtcaatgca
     4681 acagatatcg ggatgggaaa gaaaatcaat cagtcaccgc tcttagatat aagcatgatg
     4741 catgagaatc tagcggtttt tgatttgatt tatgcaccta gagaaacacg tttattaaaa
     4801 gaagcaaaaa aagtaggagc aaaaggatac aatggacttg gcatgttgat ctaccaagga
     4861 gcaatcgcgt ttgaattatg gacaaaggaa aagatgccga tccatgtgat tgaaaagctg
     4921 tttgattaaa aaaggataat agataaagat cttttattct cgcataaacg gtctcaagaa
     4981 aagtaatcct ttatgtatcg aagcatttat ttcgttattt tttattaaat tatcaaaaaa
     5041 tgataggctt ttgtcgattg gttatcgtat cctttattta tcagtaagaa acgaggagga
     5101 accacaatga gtcggatgga tcgctataag gacatccata agaaggcgaa acctctgaag
     5161 cgggatacgg ggagtatttt tgctagaaga gaacgaaaac gaacgcgtat ggaaaatgag
     5221 gaagatgcta cccgtattta tgaaagagag cagcattcat ttgaacattt gaaccaatac
     5281 gagcaacaga tatacagaga tgcaccaaga gcagaagaac aacaaaaaaa taaaaaattt
     5341 ttcaatcggc aaaagaagaa caaaccgtta aaacctcgaa gaaagcgatc gtggaaaaaa
     5401 atcattctat cgattttgct tgttttgatc ctttattcag gtatctcatt ttttattggt
     5461 aaatatgtag ctgaacatga cacaagctta gaggcagcga cttcagaaac ctttcatggg
     5521 caaaaagcga cgaatggtgc gcataatatt ttgatccttg gaagtgatac acgcggagaa
     5581 gatgccgggc gagccgatac gatcatggtc ttacagttgg atggtccttc ccataagccg
     5641 aaactgattt cttttatgcg tgacagcttc gttacgatcc caggggtagg acaaaataag
     5701 atcaattcag cttatgcata cggaggagcc gatctagtgc gtcaaacttt agtagaaaat
     5761 tttggaatcg attgtcaata ctatgcgaaa gtcgatttca aatcgtttga aaaagtgatc
     5821 gatgccttat tcatgaacgg agtgaagatc gatgcagaaa aagatctgaa tctggatggt
     5881 gtagatatta aaaaaggggt ccagaagatg gatggacatg ttcttttgca gtacgcacgt
     5941 ttccgaatgg atgaacaagg agactttggc cgtgtcagac gccaacagca agtaatgaac
     6001 gctattttca gccaattgaa gaatccattg aatctgatcc gtgcacctta tgcagctggt
     6061 aaagctttag gatatacatc cacagatgtc actgcttggt tcttgacgaa aaacctcttt
     6121 tcgattgcac gaggagctgg tggcattgat cgaataagtg tgccagtaga cggttcgtgg
     6181 aattatgggc aaagtgatta tgctggcagt attcttgaaa ttgataatca aatgaatcaa
     6241 tctgctatta cagatttttt gaataaatga tcataaaaaa gatcaagaag aagctgcgca
     6301 aggcttttgt catgaatcaa tcaaacgatt cactcgtaaa aaacgctttc ttatggtaga
     6361 tttaaccaag agaggagctg tttacattgg atatctatct gaacttcaaa aatgagtcgc
     6421 gtgaagccat cgctttttat gaaaaagttt ttcagactga agcatcaggt atcaccacat
     6481 acggtgaaat gcctggaata gaacaaatga acttgccaga agaagcaaaa aatctaatca
     6541 cgaatgcacg gctgaacatt tatgatacat tagttatgtt tgcagatacg ccagaaggaa
     6601 ttggtcctga attagttgtg ggaaataatg tttctttagt catccagaca agaaatgaag
     6661 aagaaacgaa gcgcctattt gaaagcttag ctgagggtgg taagattgag atgccactgg
     6721 atgctgttcc gtgggctcag ttgtatggga tggtaactga tcgatttggc atcaactggc
     6781 agattaacca agagtgacag ctaaagatga atattttctg gaaacatcaa gcagcaaacg
     6841 gatcatcgtt tgtttgcttg atgtttttgt gtctatttcg actatacggt atcttttttt
     6901 tattgccaga tgcgaaaata tgttccataa tagagaagtc cgcaaaaaat taagtaacgg
     6961 aggtcagaag atgaagacgg tgatactagc tgaaaaacct tcacaagcaa aagcctatgc
     7021 cgaaaccttc caacagcaaa agcggcatga agggtattat gaaatcagcg atccattgtt
     7081 tgctggtgaa gtaaccatca cttatggttt tggacatttg gtagatatgg ttgctccagg
     7141 agcttatgaa gagcgttggg caaaatggtc tttagaaaat ttgcctattt tcccagaaac
     7201 cttccgttac gaagttccaa tggacaaacg tgcacaattt tcgatcgtaa aacgagaatt
     7261 gcagtcagcc gataccatca ttattgcaac agatggtgat cgagaaggtg aagccatcgc
     7321 gtggtcgatt attcgacaag caaacgcatt ttctaaggaa aagaactatt tacgtttatg
     7381 gatcaattct cttgaaaaag aagcaatcta tgaaggtttt aagaatctcc aacctggaaa
     7441 gaactatttt ccaaaatata aagaagcgca agcaaggcag aacgctgatt ggctgattgg
     7501 aatgaatgga agtccattat atagcttgct acttcaacga aaagggattg atggcagttt
     7561 ttctcttggt cgtgtacaaa caccgacact ctatatgatt tatcagctgc aagaagaaat
     7621 caaacacttc aaaaaagaaa cgtactttga aggagaaggt ttaattacga caaacaaagg
     7681 gcagttttct ggaaaaatcg taccaaaaaa agcatttaaa acccaagaag agttaacgaa
     7741 ggaaatagaa aaacttggag cgcatttagg taagcaaaac ggacggattc ttgaagttac
     7801 gaaaaaggaa aagaggttgc atagtccacg tttattttcg ctatctagtt tgcagacaaa
     7861 gatgaatcag ctaatgaaag caagtgccaa agctacactt gatgctgctc aaggattgta
     7921 cgaaagcaag tttctaagct atccaagaac ggattccttt tacattacag aaaatgagca
     7981 tcagtatctg gttaaacatc tgcaaaatta taaaaaattt ttaggaatag aagaagtaca
     8041 gacaactgag atcaaagcaa agaaacgata tgtcgatgcg aaaaaagttc aagaacatca
     8101 tgcaattatt ccgacaaaga cgattccgac tcctgcacgc tttgcgaagc tttccaaatt
     8161 acagcaagca atctatttgc aagttttgcg cactactgtg gctatgtttg ctgcagatta
     8221 tatctacgaa gagacgaccg taatgacggg cgtacagcaa ttaaagctaa aaagcatcgg
     8281 aaagatccca ttacagcaag gttggcagga aatcttacgc atcaagtcaa aaaagaaaga
     8341 agctcagact cttcctccta tcgtagaaaa tgaagaagca gaagtagaac tgaaaagtat
     8401 ggagaaagaa acacaacctc caaaacccta taccgaagga acgttgatca cagcaatgaa
     8461 aactgcggga aaaacgctgg ataatgatga agcgcaagaa attctcaaag aagtagaagg
     8521 aatagggaca gaagctacac gagccaatat cattgaaaat cttaagcaga agcattacat
     8581 cgaagtcaat aaaaacgaaa taactgttac gccaaaagga atcactcttt gtaaggcagt
     8641 agccaatgaa ccattactga cgagcgcaga aatgactgcg cgctgggaag ggtacttgag
     8701 aaaaattggt aaacaagagg ggacaccatc tgttttttta gagaatatca aaaaattcat
     8761 cctacattta ttggcagaag ttcctaatca aatcgacaag gtagactttt cagatgagat
     8821 tagcgggaca cgtcagataa aagcgatgga gaagaaaaac gatcaattag gaagatgtcc
     8881 aaaatgtaaa aagggaatag tcatgcttta tcctaaaatc gctacatgct tgaatccgga
     8941 atgcgacttc aaattgtggc caacagtagc taaaaagaag ctgactaaaa cgaatctcag
     9001 agatttgctt tcaaaaggaa agacaagtaa agttgtcaaa ggttttactg gtaaaaaagg
     9061 gaaattcgat gcagttttag tattaaaaga agatatgaca atcggttttt cttttccatg
     9121 gatcgaaaac agtggaacaa aagcagttga tggaaacaaa gaaacatcaa gaaaaaataa
     9181 tgaaaacgaa gtagagtaaa tgaaaacaat gaaatagcgg aatatttatt ccgaaaagtg
     9241 agaatataaa taccaataaa actaaaaaat atcagtgaat caagcaaaaa cgttggggta
     9301 ggctgatttt atatagatag caaggagttt ttttatttga aaaaagtgca ttcattttta
     9361 aattatctta tgggagcaat cacgattgtg gctgtgtacc aagcatttct aaagtatcct
     9421 gattacggga cgaagttgtt gtcattgacg cacaatcaaa cagcatattc accaacgttg
     9481 attttatcga ctttgactgc aggagctaaa agcgctactt atttttttca taaaacgaca
     9541 agcatgctaa agcgaaagaa acagcgaaaa caattgttgg tggtggtagc ggctatgatc
     9601 attatttatt ttctaccagt tattacacaa gtatttcatc aatattttgg ttaagaatac
     9661 gagagtttgt gacaaaagtc atgtcacaaa cttttttctt tgtcattttt tcgtaagaaa
     9721 aagcaaaata aaagtatata cattgattaa aagtatatac ttggatataa tgtacttact
     9781 atagaatgag aatggtatag agggtggcga aatatgaaaa aaatgaaaaa gtataaaatt
     9841 agaaaatctg gcaatagcga tgtaacaact atcccaccag aagtaaaaga attcatgggt
     9901 gtgcagacag gtgacgcaat cagttatgtt tttcaatctg atggttctgt acgaatgatc
     9961 aaagcacaag aagaacctga tattgattca ttagttgatt cgatcatgaa tcaatatgaa
    10021 gacgcgttaa aagatttggt tgatttatga ggtatctttc gactaaagaa attatcaaaa
    10081 tcaacgcgaa agttatttta cgtcactcgc caggcgaaat gatcggtgta aaagatgcaa
    10141 atgcattaga tatggccgtc aaacagcctt cacaagcagt attcaatcaa gaactctatc
    10201 ctgaaatcta tgaaaaagcg gcgattttag caattaattt agctaaaaaa catccttttc
    10261 ataatggcaa taaacgaact gctcttgttg ccatgttgtt gtttcttcaa ttgaataatt
    10321 gtccagttgc tttttctcgt caagaagctg ttgattttat cataatgatt accactagtt
    10381 cattggattt cgattcacta aagtccaaga taaccagtta tttacgacaa accgcaataa
    10441 aatgaacgaa ttaaaaactt tatttctcaa ttagatcagc atgtcattaa ggaatatgct
    10501 gattttttta tgtttaatca tacaaaatag ttttttcata aaaatatgga aaatatggat
    10561 taattttgaa ataattgatt taaaaggaat acaaaagagt gaatagtagg aaatagtggt
    10621 ttagaactag tgggctgatt tttta
//
LOCUS       DADQDV010000086        10323 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.089, whole genome shotgun sequence.
ACCESSION   DADQDV010000086 DADQDV010000000
VERSION     DADQDV010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10323)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10323)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10323
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.089"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(77..910)
                     /locus_tag="J8S10_002546"
     CDS             complement(77..910)
                     /locus_tag="J8S10_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HAZ9631110.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(1214..3379)
                     /locus_tag="J8S10_002547"
     CDS             complement(1214..3379)
                     /locus_tag="J8S10_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAZ9631111.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            3639..5933
                     /locus_tag="J8S10_002548"
     CDS             3639..5933
                     /locus_tag="J8S10_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HAZ9631112.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            5926..6591
                     /gene="pgmB"
                     /locus_tag="J8S10_002549"
     CDS             5926..6591
                     /gene="pgmB"
                     /locus_tag="J8S10_002549"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HAZ9631113.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            6584..7591
                     /locus_tag="J8S10_002550"
     CDS             6584..7591
                     /locus_tag="J8S10_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HAZ9631114.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            7613..8632
                     /locus_tag="J8S10_002551"
     CDS             7613..8632
                     /locus_tag="J8S10_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAZ9631115.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(8913..10280)
                     /gene="nhaC"
                     /locus_tag="J8S10_002552"
     CDS             complement(8913..10280)
                     /gene="nhaC"
                     /locus_tag="J8S10_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HAZ9631116.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
BASE COUNT         3203 a         2242 c         1909 g         2969 t
ORIGIN      
        1 aaaaaactct ccaaacggta taatcgtttg gagagtttta ttttaatcag tttttttatg
       61 ttatatgtta tattttttat tcgttcacat ctaattcgat ttccaccccg tagtgatcac
      121 tgatgattgg actatcgatc ccatcaaaaa tccgttgata ttttttaacc tgcattcctt
      181 cagggacgaa aataaaatct atacgcaatt tttctgtatt ttgttcccaa ccatctattt
      241 tcttttccac agtagctgct tttccttttt cattcgcgac aacatacgaa tcttgaagaa
      301 gaaggcaact ttctcttaca gtataataac cttgagagtc tactggatta ttgaaatcac
      361 ctaggaaaaa aagtggtacg cgagtttcca aaaagtagtt ttccaagttt ttccactcaa
      421 aataaaagcc acttttttta tctgtccacc aagaaaagtg gcagctcgag acaaaaatgt
      481 cctgatcatc tatctttgtt ttcccaatca agatcttgcg tgtctgataa tcttctttct
      541 tttgaaattg ggagacggta aggacctgac tttccaatgt ttttttcgta agcagtgcat
      601 ttccttcttc atatttatca taaccgatgt ggctcatttc ccaactccaa aaatactctt
      661 ttccgtgttc ctttaaaagc tgaactaaac ggtaggcaaa attatcttta cggataggta
      721 cttgattctt taccggacag aacttcatta gcttcgcagg ttctacttct tcagattcca
      781 gtaattggtt gatttcttgt aaagcaatca cttcataatc ttctaacagg atcttatctg
      841 ctaattcttg caattttttc tctggttctg gctcaagcca gctatgcgtg ttgagtgtca
      901 tgaatttcat tggttttctc cttgtcttca tttcgaaaca aaagggttgt gacaaaattt
      961 ttgtcacaac ctctccagca aatagtgttc tcctgctaac tcctcagtaa taagctcaat
     1021 ggaccaggag ctattttttg tttggctgtt tttatcactt ggtgcagggc agctttttca
     1081 cgacctctcc actaaacagt attcaaactg ctgcttctcg gtaataagcc caaccaaacg
     1141 aaaaatagga ggagctattt ttgtttggct gttcttatga cttgatgcag gacagctttt
     1201 tcacaacctc tccttacatt ttaatggagc cgatcacttt accagctgtc actgtaccta
     1261 attgcttgat cactacttct tctactttat cgtttgtaaa tacgatcatg atcgttggat
     1321 ctttttcttc gttttggatc acatcaagat ccatctcagc taatttcgtt cctgttccta
     1381 cttcttggcc ttctttgaca gcaatctcaa aagctggctg attcatttgg actgtatcga
     1441 ttcccatatg gatcaaaact tcgataccat ctttcgtttc cagcccaatt gcatgtttgc
     1501 tagggaaaat acttgtcact tttccagcga tcggcgcaac aacttctctt gatgttggaa
     1561 taacagcaaa gccgtcaccc atcatttttt gtgagaatac cggatctttt acttcagata
     1621 aaggaatcac ttctccagaa gctgcggaaa ctagttcttg ttctatacct aagtattgct
     1681 tactacctgc ttgtccattt cctgtagaaa ccatttctgg ctctggaatc tctgctcctg
     1741 attgcagcag atcttcgata tctgatttca agacatctgc ttttggtcca taaactgctt
     1801 ggactccatt gtctttgacg atcaatccca tcgcccctgc tcgtttccag gcttcttcag
     1861 tccctacttt ttctcgatca tttacactta cgcgtaaccg agtcatacaa gcatcgacat
     1921 ctttgatatt ttcttttcct cccagcaaat gaatgatctg gaccacttgc tgatctgctg
     1981 ttcctgttcc gctgttagat acaacggttt cttcactgtc attgtcgtaa tttccgttac
     2041 gtcccggtgt agcaaagttg aattttttga tcaagaaatt tgctaagaaa tacgtaacaa
     2101 caccaaaagc gatcacacac aacacgaagt tgataagatc tccacctaga cccgctttga
     2161 tagctaacgg tgtccgagtc agcaattcga tattcccaaa tgaatggacc cgcaatggca
     2221 agatatctgc catcgcaaat gcagcccctt ggatcactga ataaatgaca tataatggca
     2281 cagcagcaaa cataaacatg aactccaatg gttctgttac acctgttaga aagacagcca
     2341 acgctgctga aaaatacatt gatttatatc ttgctttctt atcaggatcg acattacgat
     2401 acatcgcaaa agccattccc atcaagatac ctgaagaacc aatcatttgt cctactttga
     2461 aacgagccgg cgtccagtta tgcaacacaa actcatattg cgacatatcc cctgcacctt
     2521 taagattcac taaatcagtg gcccaagcca accataacgg atcttgccca aatacttgtg
     2581 tccccgcctg tgcgcctgat aaaatctcat acgatccgcc aagctgtgta tagttgatag
     2641 gaatcgtcag catatgatgc aatccaaatg gcaatagtaa acgttctaat gttccaaata
     2701 aaaacggtgc tagaatcggt gcgctttctt gtgattctgc aatccataaa ccaaaattat
     2761 tgattccagc ctgtacgttt ggccacacca cagcaagaat caatgccacg attgttgacc
     2821 ataagataac aacaaacgga acaaagcgct ttccattgaa aaatgacaaa gcatccggca
     2881 attttctata attatagtac ttattataag ccattgcccc gacaaatcca gcgatgatcc
     2941 ctacgaatac tcccatattc aaagctggtg cttccaatac acttgtaaaa aatcctttaa
     3001 ccatgatctt cgtaccgaac agagtgtggg taaatgcatc ttcattcgca agcatgtcac
     3061 ttgtgacacc aaagatagcc ccagtgatcc gattgattaa aataaatgag atcccagctg
     3121 caaatgctcc gcctgctctt tcttttgccc aacttcctcc tattgctaaa gcaaataaaa
     3181 tatgaagatt accaataatt gcccaaccaa tattttcaat tactccgccc gttgtgacaa
     3241 gcggcgtcca atcaggattg atcaagggaa ttgatttccc tatactgatc atcaacccag
     3301 ctgccggcat aactgctacc acaaccatta aagcctttcc aaatttttgc caaaactcaa
     3361 aactaaatat ctttttcatt ccgtttagct cctttacgca atcggtttcg ttaaacgtat
     3421 tatagcgtgc gttttctttt ttgtaaatgc tttatttttt atttttctgt ctataccatt
     3481 ctataaaacc tataatacgt gtgttccctt ctataatttt ctcctaaaaa tttatttttt
     3541 taagcttttt tctatgaaat attttctttt gtctattgac ttgtgcaatc ggttgcgttt
     3601 attatgaacg tataaaacag ctcattagga ggagaaaaat gaaacagatc aaacgactat
     3661 ttgctattga tccatggaaa atcagcacga cacaattaga taaaaaaaat cttcgactgc
     3721 aagaatcttt aacaagtatt ggaaacggtt atatggggat gcgcgggaac tttgaagaaa
     3781 cttactcagg ggaccaccat caaggtactt atttggcggg tgtctggtat cccgataaga
     3841 cacgtgtcgg ctggtggaaa aatggttatc cagaatactt tggaaaagtg atcaacgcct
     3901 tgaactttat cgcgatagat atttcgatca acgatcagct gatcgacttg gcttctttgg
     3961 aaccagaaga cttttactgg gaattagata tgaaaaatgg tgtattatct cgtacattca
     4021 caatcactac ttctactaat aaagtacgca tttccttcga acgttttctg agcattgtca
     4081 aaaaagaatc agcttatatc tatttaacta tagaaatgct tgaaggtagc ggaacagtca
     4141 aactcgtatc aaaattggat ggaaatgttc aaaacgaaga cagcaactat gatgaacatt
     4201 tttggaatga gattgatcgt ggaactatag aagaaatcgg ctatttgacg actaaaacta
     4261 ttccaaacaa ctttgggatt gaacaattta ctgttactgc agcaatgcgc catttcgtta
     4321 atggaaaatc agtcatccct gactatcacg aagatacttt agcattacat ggttgcttgt
     4381 ctgcagaatt atctcaaggt gagacatggt cagtggaaaa agaaattatc gttcttacta
     4441 gtagagatat tccagaagcg cagcaagcag aaaaagctgt ctcagaatta acgaaccaga
     4501 caaacaatta tatccaagca aaagaagagc aaacagcggc ttgggcagaa cgatggaagc
     4561 ttgccgatgt ggtcatcgaa ggagacgaag aagcacaaca aggtattcga ttcaatttgt
     4621 tccaactatt ctctacttac tacggcgaag atgaacgatt gaatatcggc cccaaaggat
     4681 tcacaggaga aaaatacggc ggagccactt actgggatac agaagcgtat gctgtccctc
     4741 tttatcttgc tttagccaaa cctgaagtaa ctaagaatct gctgaaatat cggcataatc
     4801 aactgccgca agcaatccac aacgctcagc aacaaggatt aaaaggcgcg ctttatccta
     4861 tggtcacctt cactggtgtc gaatgccata acgagtggga aatcacattc gaggagattc
     4921 accgaaatgg cgcgattgcc tatgcaatct acaattatac gaattacacc ggcgatacgg
     4981 aatatttgaa aaatgaagga ctggaagttt tagcagaaat cgcacgcttc tgggcagacc
     5041 gtgtccattt ttcaaaacga gcaaataaat acatgatcca cggtgtgacc ggcccaaacg
     5101 aatatgagaa caatatcaat aacaattggt atacaaatac gatcgcagct tgggtcttgc
     5161 gttacacgcg agaaaattat ttaacttatc aaaaagaagc tgctatcact atcagcgaag
     5221 aagaactagc caaatggaaa gatatcgcag agaacatgta cttcccagtt gacgaagaat
     5281 taggaatctt tgtccagcat gacacattct tagataaaga tctcatgcct gtatccgata
     5341 ttcccacaag cgatcttcct ctgaatcagc attggtcttg ggacaaaatc cttagatctt
     5401 gcttcatcaa gcaggcagat gtactacagg ggatttattt cttcaatgat acttttacaa
     5461 aagaagaaaa gcaaaaaaac tttgatttct atgaaccaat gactgtccat gagtcttccc
     5521 tttcgccaag tatccattcg attttagcag cagaattagg aatggaaagc aaagctgtag
     5581 aaatgtacca gcgaacagct cgcttggatt tggataatta caataacgac acagaagacg
     5641 gcttgcacat cacttccatg actggtagct ggttgtcgat tgtccaagga tttgctcaaa
     5701 tgaaaactgc ccatgatcag ttgagattcg caccatttct gccaaaaact tggaaagctt
     5761 attctttcca tatcaattat cgcggacgtt tattgttcat ctcagtcaca gatgaacaag
     5821 ttactttcga gttattagaa ggttctcctc tagaaattta cgtctatgaa cagtcttatt
     5881 ctttagcgga tcgtctagaa ataacgctaa gaaaggagga agcaaatgtt taaaggggta
     5941 ttgtttgatt tagacggtgt cattaccgat actgctgaat tccattatcg tgcttggcga
     6001 aagcttggtc aggaaatcgg cattacgatc gaccacacat tcaacgaaca gctaaaaggc
     6061 gtcagccgag aagactcact ctctttgctt ttagcttatg gcggaaaaga acactctttt
     6121 tcaaaggaag aatttgcaga attagcgaaa agaaaaaacg attattattt agagatgatc
     6181 cagacgatcg aaccaaaaga tgtcttcccc ggggtcgtgc ctttactgga ttctttaaaa
     6241 gaagaaaaaa tcaagattgc tcttgcttct gcaagtaaaa acgggccatt cctacttgaa
     6301 aaaatgggtc ttacacctta ctttgatgct attgccgacc cggcagaagc aacaaacgga
     6361 aaacctgcgc cagatatctt cctccttgca gcaaaagctg tcggactaaa agcagaagaa
     6421 tgtatcggga tcgaagacgc gcaagccggt atccaagcca tcctctcaag tggcgctcaa
     6481 ccaattggcg tgggacgtgc tgaagacctt ggagaggaga tcccgcttgt ccctgatacg
     6541 acttttctta cgatcgatta cttgaaagaa aagtggcatg accatggata atccagagat
     6601 ctccgtcgta ccagttccag agactgaaat aaagaaaatc acattgaaga acgactactt
     6661 agaagtcgtt cttctcaatt acggtgcccg cctgcaccaa atcttcgcac cagacaaaga
     6721 aggaaaatca gaaaatgttt tattgtctta cgatcgtttc gaagatgttc taacagacaa
     6781 aagctttttt ggagcaactg tcggacctgt agccggaagg atccgggatg cttcttgggg
     6841 tgagcataga ttggagaaaa actgcggatc acaccatatc cacggtggca cgaaaggctg
     6901 gtctttccaa ttttgggaag tagaagtttt caaaactcca tcatcaatag gtgtggtctt
     6961 ttacttaaaa gatgaatttt ctacctatcc aggaccaatc actgctacga tcacttaccg
     7021 tttaacaaaa aacgaattag agatgacaac ctctgctagt agccttgttg aaaccatctg
     7081 caatccgacc aaccatgcct acttcaacct ttcaggaaat ggaacaagag acatctatga
     7141 acatcagtta acggtctttt tagatggtgt gcttgaatta gatcaagaaa aactgcctac
     7201 tggaaattgg acaaaaaaag aaaaactgcc aatcgacttt agaaaatccc caacactgca
     7261 agagatcctt gcatgttatc cagatggact agatgatgta tttcttttgc atcatcctag
     7321 gctttccaaa acttccttac aattattcga gaagcattct ggtcgccaaa tgactatagc
     7381 aacttctaat aaaagtatgg tattattttc tacgactgga ttcgaagctg atttctctgt
     7441 caatggaaaa cagatgcatt caaactacgg attagcaatc gaaccgcaag aaatccctga
     7501 tatcgttcat ttccccaaat ttggatcgat caacctccat cctggtcaag aacggatcag
     7561 tcagacgatt tatcggttct ctgcacaata acaagagaaa ggtgttttta tcatggctat
     7621 taccgtaaaa gatgtggcga aaaaagccgg tgttgccacc tcgaccgtct ctcgtgtcat
     7681 caacgatcat cctagtattt ccgagacaac aaagaagaaa gtccgaaaaa ttatggatga
     7741 actaggttat gttcctaaca tgactgcccg caatctagga aaacgcattt ccagtgccat
     7801 cggcgtaatc ttaccccctc ttgattcaaa agagcggatc ggtaacccat tttatcttga
     7861 gatcatggaa gcaatcaacg aagaagcgcg gaattatgat atgactacag caatcgctac
     7921 tgctaaaaat tttgaattgc tgttagagaa cgtccagcgt atgcatttac aaaaacaagt
     7981 agatggtttt attctagtgt attcagatag tcaagatact gtcattgatt atttatacca
     8041 aaaccacatc cctttcactt tgatcggaca gccttatcat catgagaacg aaatcgttta
     8101 tgtagataat gataaccagc ttctaggtaa acaagcaaca gaatttttga tccagaatgg
     8161 acataagaat atcctgtttg tgacaaacac gactcatgaa agtttgtatt tcgaacgata
     8221 tttcggttat caaaaagcaa tgatgatggc tggtcttcct gcgttatcca gtgtagtact
     8281 agagcatccg gaggattatc tgtcctttga gaaaacgttg aaagaaaacg aagccacagc
     8341 attggtggtc attgacgata tcttcgccct tcgcacgatg cagttggcgc aaatgtatgg
     8401 ctatgtcatt ccagagacac tctccgtcat tagcttcaac aactcgatct tctcaacatt
     8461 aacacaccct taccttacaa gtatcgatat cgatatctcc gaattaggac gtgtcgctat
     8521 gcaaaagctg cgcgaattga tccatgaaga attgagcagt ggcgtacgtt tggtcatccc
     8581 tcatcgcttg atcaaaagag agacagtcgt tcctttagaa aacccatact aaatagctga
     8641 ctcactaaat acgctgacca tttatcctat ggtcagcttt ttatgtaaaa gaagatacta
     8701 cttctaacac attgtttatc tgtaaaaaag agcgtgggac aaaagtaaag aacacttttg
     8761 tctcacgctc taaacacgta taaacggcgg aagcagaagc aactccttcg gaaataagct
     8821 gaaattcaca aaaatttaaa aagcaatttt cttgagtttc ttcttatttc ttggagttaa
     8881 acgcttctgt cccagcctct tttttccttc cttcaatttt ttacacgtcg acgattcaat
     8941 aaaaaaccgc ctaatattgt aaagacaggt gcaagaatcg agaaaaaggc gaatggcaag
     9001 taatgcaacg cgctaacttt catcgttccc ataatgaatg tgccgctgac tccccacggt
     9061 acgagagaat tgacggtcgc acctgaatcc gctagtgttc gtgtcaaata ggtttttgat
     9121 aagccaacgt catcaaaaga acgcttgaat gtttctcctg gaagaatgat ggacagatac
     9181 tgttctccaa cgatcagatt gattccgata cagctcaagg cagtaaaccc gactaaacga
     9241 gaaggtcggt ccatcttttc ttttaattct tgaacgatgg tatcaacgat cagatatttg
     9301 atcagtaacc cacctaatgc caatgcaagt aaaatcaaac tagcagaacc taacatactc
     9361 atgatcccgc ctcgagaaag cagttcatct agctttggat caggtgtatt tgcgacataa
     9421 ccattcatca agatgtctgc tgcttttccg accgtcaaac ttttctcatg gataaaagaa
     9481 agaacgagag cagctgtcga tcccgctagt aatgtaggga tagccggaat ttttttgatt
     9541 gcccccccaa ataaaataac tagtggaatc aatgtccaag gagagatcca aaagctcgct
     9601 ttcatgtttt ggatcatttc attgatacta gctagatcgg ctgaatgact gttatgtcct
     9661 aatatcgtat aaaaaatcaa cgaaaggacg aatgctggga aatccgtata acgcatacca
     9721 gcgatatgtt cgaatagatt aactcctcca atacccgctg ccaagttggt cgtatctgat
     9781 aaaggcgagc agttattccc taaaaaggca ccggaaacga ctgcgcctgt agtcattgca
     9841 tcattgaatc caagtaaatg accgatcccc aaaaaagcaa ttccaatcgt cgaaatcgtt
     9901 gtaaatgaac tgccgacagt cactccgaca attgcacaaa caagaaatgc tgtcggtaaa
     9961 aagaaacgca cagaaacaag tttaaatcca taaaccataa tcgtagggat ggttccagat
    10021 aaaatccatg aagcaactaa gacaccaatc aaaagaaaaa tcaggattgg aatgatccct
    10081 ggagtgattc ctttgatgat cccgtcatgg atctcatccc atgtgaactt tttaaatctg
    10141 ccataaaaca acaaacacat gaaagctgca aggatcggga tatgtggcga gagctggaat
    10201 ccgatgatca gtactcctag gagtgccaac aacacgatca atacagcgat actttctttt
    10261 aaagaaatat ttttattcat cgtcgatctc ctatttcaaa tgaaaaggcc ctgccatgaa
    10321 aaa
//
LOCUS       DADQDV010000087        10246 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.090, whole genome shotgun sequence.
ACCESSION   DADQDV010000087 DADQDV010000000
VERSION     DADQDV010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10246
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.090"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            314..1093
                     /locus_tag="J8S10_002553"
     CDS             314..1093
                     /locus_tag="J8S10_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631117.1"
                     /translation="MEKPFVKSLTAVAVGAGAIAICLFGYHINNQRQHQQRINYAESA
                     ITNQKDTLTSLSKEVDKLYSTKEKIFLNPEITEETITSLSNKLSSVKLSADDYDIKES
                     ELPKEAVAIQDEKKAIVTQLDSAESKLKIQTAVNDLFTKNVSNWQQAVDDVIIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADIQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTVLSQIEQIRNEKISAAYATKAQTVAEQMGYSNISY"
     gene            1139..2083
                     /locus_tag="J8S10_002554"
     CDS             1139..2083
                     /locus_tag="J8S10_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAZ9631118.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFPIGKITLNGDQALSYSRMRYEDPNGDYGRQGR
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMNFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            2099..2878
                     /locus_tag="J8S10_002555"
     CDS             2099..2878
                     /locus_tag="J8S10_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HAZ9631119.1"
                     /translation="MEETISLKEIFETLRKHLVIIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     EQIKDAISVNQAENSQMFSIQAISTNAVAAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLMTGLMLGMMVGVGLAFLLELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSAKELNAGIRKKGPAQTQPKATNDKTAPSRRSRSRV"
     gene            2890..3588
                     /locus_tag="J8S10_002556"
     CDS             2890..3588
                     /locus_tag="J8S10_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HAZ9631120.1"
                     /translation="MARTQKQKAAQTHAVSLVTLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVIYKTFKLNNAS
                     GLSTVLSSSGSVADEIQRTPVDNLSILPSGPKPPNPSELLSSPRMDQILAEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENTSRKESLTKAKELLDMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            3616..4380
                     /locus_tag="J8S10_002557"
     CDS             3616..4380
                     /locus_tag="J8S10_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HAZ9631121.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAERLFFELLELGKIPVIVHPERNAHFREDPNHLLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKTMVKHNLVQMAASDAHGVSKRTFYLKECYEQIAKEFG
                     KEKVVQMKQVAKDLINGDEINYPIYEEVKKKKFGLF"
     gene            4424..5875
                     /locus_tag="J8S10_002558"
     CDS             4424..5875
                     /locus_tag="J8S10_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HAZ9631122.1"
                     /translation="MYRKNSSGWSKHIDFILLDLFCVQLAFYISYVMRQGDWNPYVIP
                     IYRHMAIFIELENLTIIFLFEAYKNVLKRGYYKEAVASIKQSFMLLLVCSLYLITMQD
                     GNDYSRVSLFIMGVVYGLLTYIIRILWKGLLHHRMKNGEDVSLVIVTSQKIAKNVVRN
                     LKEKNYGMYKLSGVIVVDRDMYGTTIGGVPVVANADNAAEYLLQNWVDEVFINVDESV
                     PYPKELIARCSEMGLAVHMNLTKVSDSTRGKQFIGRVGDYTVITSSINVMTMRQAFIK
                     RTIDILAGIIGCIATGVIFIFVAPVIYIKSPGPIFFAQERIGQNGKTFKMYKFRSMYM
                     DAEERKAELMKENKMSNNLMFKMDFDPRIIGNKILPDGTKKTGIGQFIRSTSLDEFPQ
                     FYNVLMGKMSLVGFRPCLKSEYEKYDFHHRARIAMKPGITGMWQVSGRSDITDFEEVV
                     KLDAEYIRNWSMGLDFRILFRTVKTVLHRNGSM"
     gene            5907..7043
                     /locus_tag="J8S10_002559"
     CDS             5907..7043
                     /locus_tag="J8S10_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAZ9631123.1"
                     /translation="MARKKLKICMLGHKRIPSREGGIEIVVEELATRMVALGHEVTCY
                     NRSGHHVSGKEFDQHKNKEYKGVKLKTIFTLNIKGIAAMSSSVFGGIRAAFGKYDIVH
                     FHAEGPCAMLWLPKLFGKRCVATIHGLDHQREKWNKLASTYIMLGEKCAVKFADEIIV
                     LSESVQNYFEDIYGRKTRFIPNGVKKIEIKSAGLITEKYGLTKDSYILFLGRLVPEKG
                     IRYLIEAFKDVQTDKKLIIAGGSSDTDEFANELKELAKGDERIIFTGFVQGQELEELY
                     SNAYIYTLPSDLEGMPLSLLEAMSYGNCCIVSNISECTEVVEDKAMIFKKSDVSDLKI
                     RLEEACNQSEMVKVLKNQATEFICSKYNWDKIVQETLNLYRGNI"
     gene            7043..8149
                     /locus_tag="J8S10_002560"
     CDS             7043..8149
                     /locus_tag="J8S10_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HAZ9631124.1"
                     /translation="MIRILQCVNDMHRAGLETMLMNYYRNIDRTKIQFDFLTHRPYKS
                     DYDEEIISLGGKVYYAPRLYPQNYPKYFKWMEQFFKDHPEYEIVHSHIDAMSYLPLKA
                     AKKAGIPIRIAHSHNTSIDRDFKYLLKQYYRCKLTSVLTHEFSCGKVAGDFLFRNDKF
                     TLIPNAVDAKKFYYDESIRNDVRMKLGISSQTFVMGHIGRISYSKNHRFLIEIFKEFH
                     AIKNNSVLLIIGTGDMEEEIKNYAKKSGIDDDIKFLGNRNDIEKFYQAFDVLMLPSLF
                     EGVPLVGIEAQFADLPCFFSEKVPTEVAFSDKTNFISLNQSAKEWAREIANVDISHRD
                     SERSILIKADYNIQTAYKILESKYYELFELIQRG"
     gene            8155..9177
                     /locus_tag="J8S10_002561"
     CDS             8155..9177
                     /locus_tag="J8S10_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAZ9631125.1"
                     /translation="MTQKHSSIKRIIHRISEELNATRRIAKITSWKEAFATLQAKIDI
                     QVMNRNGYNESKKQKEHLLKKHEVMLKYYEKTFSDFLKTYDYSQNQIINQSKSPYSNC
                     IWVCWWQGLDQSPEIVKACVKSIKRNAGKHTVIILTEDNYRQYVDIPKWVEEKKNKGI
                     ITRTNYSDLLRLSLLAKHGGLWLDATFYCTKPIPDEYFDIDIWSIRRPDYAHASVASG
                     YFAGYSLACNQESRWMFAIIRDFFLNYWKNNDMMVDYLMIDYMIVLAQRINHEIAQTF
                     DKIPSNNPLCDELIKNLNNIYDEKVWNLLKKDTLLFKLTWKQSFKKQKDDKVTFYGML
                     VENKLL"
     gene            9199..>10246
                     /locus_tag="J8S10_002562"
     CDS             9199..>10246
                     /locus_tag="J8S10_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAZ9631126.1"
                     /translation="MKHKVSVIVPIYNVEKYLRKCVDSLLSQTLKEIEIVLVDDGSPD
                     ASGEIADEYQKKYSNVKTIHRENGGLGPARNTGIENATGEYVAFLDSDDWVESDMYEK
                     LYLVASKENADIVVSGHCDFANDKAMVKKQHPLSGNVYDTPNSIKNVRKNLFGHSPKD
                     QEVEAFPMSVCMSLYNKNLLDKYRLRFEKILSEDTIFNLNAYDVANKIAFTEYTDYCY
                     RKEEQESITKSLSPNKQTEFKEFLITLKAIASKEDLECQIRAKRMAIDYCRLYVGLVD
                     DANLGIKEKRKYIKKFIEDEGLIQCWKGYPTNTLPFQQKFFHKMLECKCYTILLLLSR
                     IRKIIKNMTRKKLFI"
BASE COUNT         3746 a         1442 c         2100 g         2958 t
ORIGIN      
        1 aactattatt aattcaatgt taattttttt gttattctat tttttgtgta acttttaaaa
       61 acacctatga aaattatgga aataaaaatg aaatcgatta atttttatct tattaatgtt
      121 ttatttactt ttaaatcgta aattgcccta gtcaagaaaa cagtttgtgg tatgattata
      181 tagggaaaac ttgtttacaa atatttctgt gaatatatta gtttaattat gtttttttaa
      241 ataaaaagct gtcattttta tgtaagtgaa ttatatctta atttatctat catcaatact
      301 taggagtgaa tctatggaaa agccattcgt caagtcattg actgctgtgg cggtaggtgc
      361 aggtgctatt gcgatctgtt tgtttggata ccatatcaat aatcagcggc aacatcagca
      421 acggatcaat tatgcagaat ctgccatcac caatcaaaaa gacaccttga cttctttatc
      481 aaaagaagta gacaagctgt atagtacaaa agaaaaaatt tttctaaacc ctgaaataac
      541 agaagaaaca atcacaagtt tgtcaaataa gctatcctct gtcaaacttt cagcagatga
      601 ttacgacatc aaagaatcag aattgcctaa agaagctgtt gcaatccaag atgagaagaa
      661 agcaatcgtg acacagttag atagtgcaga atcaaaactg aagatccaga cagctgtcaa
      721 cgatttattt actaaaaatg tatcaaactg gcagcaagct gtagacgatg tcatcatcaa
      781 agaaaaggtg acaagtgcag atgtcgctcg tgtacgtgaa aatatgagct tttttaaaga
      841 tagtccttgg aaaacggttg ttatgcaata tctaggattc gctgatattc agatcgcgca
      901 agtcacgcaa ctagatcagt tattcgatac gatgttaaag gatggtcaag tgactgccac
      961 cgctacttac gatcaatatt tgacggtgct cagtcaaata gagcagatcc ggaatgaaaa
     1021 aataagcgca gcatacgcaa caaaagcaca aactgttgct gagcaaatgg gctatagcaa
     1081 tataagctat tgacagttaa aacgttgatt caagcaaggt tagcaaacgg aggaaactat
     1141 ggcaagacga agaagaaaat caagagggaa aaaaatattt ctgattattt tagcagttct
     1201 tatcgtatta gtattagcaa ttgtaggagt aggagcaaaa ttatatctgg atctctcaca
     1261 ttctattgag aaaacttacg aatcagtgga acgaacccaa ggagaacgaa cgaaaccagt
     1321 tgatctggac aaacaagaat ctttctctgt tctattgatg gggattgata ctggagattt
     1381 aggtcgggtc gatcaaggaa gatcagatac gatgatggtt gccacagtca gtcctgaaga
     1441 caaacagaca acgatcgtca gcattcctcg tgatacgtat gtcgacatcg taggtcgtga
     1501 cacaaaagac aagatcaacc acgcttacgc attcggcgga gctgccatgg cgatggatac
     1561 cgtacaaaaa tatgtagaca tcccaatcga tcactatgtc tctatcaata tgaaagggct
     1621 aaaggaactc gttgatgcag ttggtggtat cgaagtcaat aatgacctca ctttctcaca
     1681 agatggctat gactttccaa tcggtaaaat tacattgaac ggggatcagg cattatctta
     1741 ttctcgtatg cgttatgaag acccaaatgg tgattacggt agacaagggc gccaaagaaa
     1801 gatcgtagaa ggcgtagcga aaaaagtatt gagtctaaac ggtgtcagca actatcaatc
     1861 cgttttgaat gctctagagt cgaatatgaa aacagacatg aactttgatg aaatgaaaaa
     1921 aattgcttta gattatcggg aggcatttgg tacgattaag caagatcagc tgcaaggaga
     1981 aggcttcatg caagataata tctcctatca aaaagtcagt gatcaagaac ttgatcgtgt
     2041 gaaaaaagaa ttaaaagatc aaatgaatct agagaataaa taggaaagtg gagaaaaaat
     2101 ggaagagaca atcagcttga aagaaatttt tgaaacatta cgcaaacact tggtaataat
     2161 catcatctca atgtttgctg gcttggccat ctcaggaatc gtaacatttt tcatcttgac
     2221 accaaaatac agttcacaag cacaattgat cgtgacactg ccacaatcag acactgcaaa
     2281 tgtcaatgat gtcaatacga acctgcaaat gatcaatacg tataaagata tgatcgtcag
     2341 tgatttagtg ctcaatgaag tcaaagatcg tttagaaaca gaagacaatg tgaaaatgac
     2401 tgctgaacaa atcaaagatg ccatctcagt taatcaggca gaaaattcac aaatgttctc
     2461 gattcaggca ataagtacga atgcagtggc tgctcaacag atcgctaaca caacttcaca
     2521 agttttccaa gagaacgcaa aagatgtgat gaatgttgat aaaatctcga tcatttcagg
     2581 tgcagttgcc aatacgacac ctgtttcgcc aaataataaa ttgaatttaa tgactggctt
     2641 aatgttagga atgatggtag gtgtaggtct ggcattctta ttggaattac tcgatcggac
     2701 agtgaaagat gaaaaatatg tgacagatac attaggattc ccaatcttag gaacagttcc
     2761 agaaatgtca gcgaaagaat tgaatgctgg tatccgtaaa aaaggaccag ctcagacaca
     2821 accaaaagct acaaacgata aaacagcgcc atcacgcaga agccgctcaa gagtctagga
     2881 ggaaagaaaa tggcacgaac acagaaacaa aaagcagccc aaactcatgc agtcagtttg
     2941 gtcacactca ccaatccctc ttcaccaatc gctgaacaat atcgtacgat tcggacgaat
     3001 atccagtttg cctccgcagc tggtcagcaa atcaaaacga ttgttgtgac ttcatcagga
     3061 cctggagaag ggaaatcgac cactgcagca aacattgccg ttgtttttgc caaatctggt
     3121 caacgggtgc tgctagtcga tgcagactta cgtaagcccg tcatctataa aacgttcaag
     3181 ttgaacaacg caagcggatt aagtactgtt cttagttcat caggaagtgt agcagatgag
     3241 atccaacgaa caccagtcga caatttgtcg attctgccaa gtggacctaa accaccaaat
     3301 ccatcagaac tactaagttc gccaagaatg gatcagattt tagcagaagc aagacaacta
     3361 tttgatgtag tgatcttcga catgccgcca gtcgttgccg taacagatgc acagatcatg
     3421 tcttcaaaaa cggatggcac cttattggtc gtacgggaaa atacgtcacg aaaagaatca
     3481 ttgactaaag caaaagaact gttagatatg gtacaagcac gagtcttagg tgtcgtatac
     3541 aacggagcag aacacagcaa agatgctggt tattactacg gaaattaagg aataagaaga
     3601 gaggagacaa gagaaatgat cgatctacat tgccatatcc taccaggaat cgatgacggg
     3661 gcagaaaact tagaagcaag tattgcaatg gctgaaaaag cgattcagca aggcattacg
     3721 catattttat gcacaccaca ccacaataat ggaaaataca gcaatgaaaa atcacaagtc
     3781 atttctctag tcgcttcgtt acaagccgaa ttagagaaaa gacagttgcc tttgacgtta
     3841 ttggaaggac aagaagtacg tattaccgga acgctcatcg aagacatcca ccgagatgaa
     3901 attttattta cagatttaga tgatacatat cttctgatcg aatttccgac actggaagtg
     3961 ccgttatatg cagaacggct tttttttgag ttgttagaac taggaaagat accagtgatc
     4021 gtccatccag aacgcaacgc gcattttcga gaagacccaa atcatttgct tccgttccta
     4081 gatatgggat gtttggccca acttactgcg ccaagttatg ttggtgtatt tggcaaagat
     4141 atccagaaaa cagccaaaac aatggtcaaa cataatctcg tgcagatggc tgcttctgat
     4201 gcacacgggg tctctaagcg caccttttac ttaaaagagt gctatgagca gattgccaag
     4261 gagtttggta aggaaaaagt agtacagatg aaacaagtcg caaaggatct gatcaacggg
     4321 gatgagatca attatccaat ctatgaagag gtaaaaaaga agaagtttgg tttattttag
     4381 ttctttattc gtagataaaa aggaaatgag gagagagtga gagatgtata gaaaaaactc
     4441 aagtggttgg tctaaacata ttgattttat tttattagac ttattttgtg tccagcttgc
     4501 tttttatata tcatatgtaa tgcgacaggg tgactggaat ccgtatgtga ttcctattta
     4561 tcgccacatg gcaattttta tagaacttga gaatcttacg attatatttt tatttgaggc
     4621 atataaaaat gttttaaaaa gaggatatta taaagaggct gtagcttcta taaagcaatc
     4681 ttttatgctg ttacttgtgt gcagtttata ccttattaca atgcaggatg gaaatgatta
     4741 ttccagagtt tctttattta taatgggggt ggtgtatgga ttattaacat atataattcg
     4801 tatactttgg aaagggttgt tgcatcaccg catgaaaaac ggtgaagatg tatcgttagt
     4861 tattgtaaca tctcaaaaga ttgcaaaaaa tgtagttcgt aatcttaaag agaagaatta
     4921 tggcatgtat aaacttagtg gtgtgattgt agtagacaga gatatgtatg gaactaccat
     4981 cggaggtgtc ccagtagttg caaatgctga taatgcagcg gaatatcttt tacagaattg
     5041 ggtagatgaa gtattcatca atgttgacga aagtgttcca tatcccaaag aattaatcgc
     5101 cagatgttcg gaaatgggac ttgctgtaca tatgaatctt acaaaagtgt ctgatagtac
     5161 acgtggaaaa caatttattg gccgagttgg tgattatact gttattacat ctagtattaa
     5221 tgttatgacg atgaggcaag catttataaa gagaacgatt gacattcttg ctggaattat
     5281 tggatgtatt gcaacaggtg ttatttttat cttcgtagca ccagttattt acatcaaatc
     5341 accagggccg attttctttg cacaagaacg tattggtcaa aatggtaaga catttaagat
     5401 gtataagttc cgtagtatgt atatggatgc agaagaacgc aaagcagagt tgatgaaaga
     5461 aaataagatg agtaataatc tcatgtttaa gatggatttt gacccaagaa tcattggcaa
     5521 taaaatactt cctgatggaa caaagaagac aggaattgga caatttattc gatctacatc
     5581 attggatgag tttccacaat tttataatgt cctaatggga aaaatgagcc tggtggggtt
     5641 tagaccttgc ttgaagtcag aatatgagaa gtatgatttt catcatcgtg cgagaattgc
     5701 gatgaaacct gggattactg gaatgtggca ggtgagtggt agaagtgata tcacagactt
     5761 cgaagaggtt gtaaaacttg atgcagaata tatcaggaat tggagtatgg gattagattt
     5821 tagaattttg tttaggacag tcaaaactgt gcttcataga aacggttcca tgtaagataa
     5881 agatactata gaaggagtaa aacgtgatgg caagaaaaaa attaaaaatc tgtatgctag
     5941 gtcataaaag aattccatca agagaaggtg gaattgagat agtggtagaa gaattggcaa
     6001 cgcgaatggt tgcacttggg catgaagtga cttgctataa tcgaagtggt catcatgtta
     6061 gcggaaagga atttgaccag cataaaaata aagaatataa aggtgtaaaa ttaaagacta
     6121 tttttacatt aaatataaaa ggaattgcag caatgagttc ttcagtattt ggtggaatta
     6181 gagcagcatt cggaaaatat gatattgttc attttcatgc agaaggacca tgtgctatgt
     6241 tgtggttgcc aaaacttttt gggaaaagat gtgttgcaac aattcatggt ctagatcatc
     6301 aaagagaaaa atggaacaag cttgctagta catacatcat gttaggggaa aagtgtgctg
     6361 taaaatttgc agatgaaata attgtactta gtgaaagcgt ccaaaattat tttgaagata
     6421 tatatggaag aaaaacaagg tttataccaa atggcgttaa aaaaattgaa ataaaatcag
     6481 caggattgat tacagaaaag tatggattaa caaaagattc ttatattttg tttttggggc
     6541 gattggttcc cgaaaaagga attcggtatc taattgaggc atttaaagat gttcagacag
     6601 ataaaaaact tataatagcc ggaggaagct ctgatacaga tgaatttgca aatgaactaa
     6661 aggaattagc aaaaggtgat gagcgaatta tatttactgg atttgtacaa ggacaggaat
     6721 tagaagaatt atatagtaat gcgtatatct atacacttcc aagtgattta gaaggaatgc
     6781 cattaagttt gttagaagca atgagttatg ggaactgttg tatagtttca aatatctcag
     6841 agtgtacgga agtagtagaa gacaaggcta tgatttttaa gaaatcggat gtaagtgatt
     6901 taaagataag attagaagag gcatgcaatc aatcggaaat ggttaaagtt ttgaagaatc
     6961 aagctactga gtttatttgt agtaaatata attgggataa aatcgtacaa gaaacattaa
     7021 atttgtatag gggaaatata taatgattcg aatattacag tgtgtgaatg atatgcatcg
     7081 tgcagggttg gagacgatgc taatgaacta ttataggaat atagatcgaa ctaaaattca
     7141 gtttgatttt ttgacacatc gtccatataa aagtgattat gatgaggaaa taataagtct
     7201 tggaggaaag gtctattatg caccgagact ttatccacaa aattatccta aatattttaa
     7261 atggatggaa caatttttta aggatcatcc agaatatgag attgttcatt ctcatattga
     7321 tgcgatgagt tatttacctt taaaagctgc aaaaaaagct gggattccga tacggatagc
     7381 acatagccat aatacatcga tagatagaga ttttaaatat cttttaaagc aatattatcg
     7441 atgtaagtta acgtctgttt tgacacatga attttcatgt ggaaaagtag caggtgattt
     7501 tttgtttcga aatgataaat tcactttgat tccaaatgca gtggatgcta aaaaatttta
     7561 ttatgatgaa agtattagaa atgatgtacg aatgaaatta ggaatttcaa gtcagacgtt
     7621 tgtaatggga catattggaa gaatttcata ttctaaaaat catcgttttt tgattgaaat
     7681 ttttaaagaa tttcacgcta ttaagaataa ttccgtatta ttaattattg gaactggtga
     7741 tatggaagaa gaaataaaaa attatgcaaa gaaaagtggc atagatgatg atattaaatt
     7801 tttaggaaat agaaatgata tagaaaaatt ttatcaagca tttgacgtat taatgttgcc
     7861 atcattattt gaaggggttc cgttagtggg tattgaagct caatttgcag atttaccgtg
     7921 tttcttttcg gagaaagttc ctacagaagt tgctttcagt gataagacca atttcataag
     7981 tttaaatcaa tcggcaaaag aatgggcgag agagattgca aatgtagata tctctcatcg
     8041 agattcagaa cgttcgattt taataaaggc agattataat attcaaacag catacaaaat
     8101 cttagaatca aaatattatg agttatttga attaatacaa agaggttaaa gaatatgaca
     8161 cagaaacatt caagtataaa aagaattata catcgcatat ccgaagaatt gaatgcaaca
     8221 agacgaattg caaagataac atcttggaag gaagcatttg ccacgttaca agctaaaatt
     8281 gatattcaag tcatgaatcg taatggatat aatgaaagta aaaaacagaa ggaacattta
     8341 ttaaaaaaac atgaggtaat gctgaagtat tatgaaaaga ctttttcaga ttttttgaaa
     8401 acatatgatt atagtcaaaa tcaaataatt aatcaatcaa aatcaccata ttctaactgc
     8461 atttgggttt gttggtggca gggattggat caatcgccgg aaattgtaaa agcttgtgta
     8521 aaatcaataa aacgaaatgc agggaaacat actgttataa ttttaacaga agataattat
     8581 agacaatatg ttgatatacc aaaatgggtg gaagaaaaga aaaacaaagg aatcattacg
     8641 agaacaaatt attctgattt attaagatta tctttgctag caaaacatgg aggtttgtgg
     8701 ttagacgcca cattttattg tacaaaacca ataccagatg agtattttga tatcgatatt
     8761 tggtctatta ggaggcctga ttatgctcac gcatccgtag catcaggata ttttgcgggt
     8821 tattcattag catgtaatca agagtctaga tggatgtttg ctataattag agactttttt
     8881 ttaaattatt ggaaaaataa tgatatgatg gtggattatt tgatgataga ttatatgatt
     8941 gttttagcac agagaataaa tcatgaaata gcacagacat ttgataaaat acctagtaac
     9001 aatccattat gtgacgaatt gattaaaaat ttaaataata tatatgatga aaaagtatgg
     9061 aacttattaa agaaagatac tttactgttt aagttgacat ggaaacaatc ttttaaaaag
     9121 caaaaagatg ataaagttac tttttatggg atgttggtag aaaacaaatt attataaata
     9181 ttagaggtat aaaaagttat gaaacacaag gtaagtgtga tagtaccaat ttacaatgtt
     9241 gaaaaatatt taagaaaatg tgtggatagt ttattgagtc agacattaaa agagatagaa
     9301 atcgtattag ttgatgatgg ttcgccagat gcttcggggg aaatagcaga tgagtatcaa
     9361 aaaaaatatt ctaatgtaaa aacaatacat agagaaaatg gggggttagg accggcaaga
     9421 aatacaggaa ttgagaatgc gacaggagaa tatgtggctt ttcttgattc agatgattgg
     9481 gtagaaagtg atatgtatga aaaattatac ttagttgcgt ccaaagaaaa tgctgatata
     9541 gtagttagtg gacattgtga ttttgcgaat gacaaagcta tggtgaaaaa gcaacatcct
     9601 ttgagtggga atgtatatga tacgcctaat agtattaaaa atgtacgaaa aaatttattt
     9661 ggacatagtc caaaagatca agaagtagag gccttcccga tgtcagtatg tatgtctttg
     9721 tataataaaa atctgctaga taaatataga ctaagatttg aaaaaatttt atctgaagat
     9781 acaattttta acttgaatgc atatgatgtc gcaaataaaa ttgcttttac agaatataca
     9841 gattattgtt atagaaaaga agaacaagag tctattacaa aaagtttatc tccaaataag
     9901 cagacggaat ttaaagaatt tttaataact ctaaaagcta tagcatcgaa agaagattta
     9961 gaatgtcaaa tcagagcaaa acgtatggca attgattatt gtaggcttta tgtgggctta
    10021 gttgatgatg caaatttggg aattaaagag aaaagaaagt atataaaaaa atttattgaa
    10081 gatgagggat taattcaatg ttggaaggga tatcctacaa atacgctacc atttcaacaa
    10141 aaattttttc ataaaatgct tgaatgtaag tgttatacaa tattgttgtt gttaagtaga
    10201 attagaaaga taattaaaaa tatgaccaga aaaaaattgt ttataa
//
LOCUS       DADQDV010000088         9886 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.091, whole genome shotgun sequence.
ACCESSION   DADQDV010000088 DADQDV010000000
VERSION     DADQDV010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9886)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9886)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9886
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.091"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(109..2229)
                     /locus_tag="J8S10_002563"
     CDS             complement(109..2229)
                     /locus_tag="J8S10_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAZ9631127.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLARGKNVIYIHLESFQQFLIDYKLTDENG
                     LQHEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYTSAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHNG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            2459..3637
                     /locus_tag="J8S10_002564"
     CDS             2459..3637
                     /locus_tag="J8S10_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HAZ9631128.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIIGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            3653..4411
                     /gene="aroD"
                     /locus_tag="J8S10_002565"
     CDS             3653..4411
                     /gene="aroD"
                     /locus_tag="J8S10_002565"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HAZ9631129.1"
                     /translation="MVRVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLVGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            4434..4919
                     /gene="ybaK"
                     /locus_tag="J8S10_002566"
     CDS             4434..4919
                     /gene="ybaK"
                     /locus_tag="J8S10_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HAZ9631130.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSRIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(4990..6243)
                     /locus_tag="J8S10_002567"
     CDS             complement(4990..6243)
                     /locus_tag="J8S10_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAZ9631131.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            6360..7709
                     /gene="gdhA"
                     /locus_tag="J8S10_002568"
     CDS             6360..7709
                     /gene="gdhA"
                     /locus_tag="J8S10_002568"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HAZ9631132.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNVQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            7821..9167
                     /locus_tag="J8S10_002569"
     CDS             7821..9167
                     /locus_tag="J8S10_002569"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HAZ9631133.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(9475..9861)
                     /locus_tag="J8S10_002570"
     CDS             complement(9475..9861)
                     /locus_tag="J8S10_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAZ9631134.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYPEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
BASE COUNT         3148 a         1800 c         2025 g         2913 t
ORIGIN      
        1 ctgagccaga atgaggttca ttctgaccca gatttgattt tgtacaaccc atcagtcctt
       61 attgacaaag agcctaattt tgtcgctgct ccttttaaat ttattttatc attcggaaga
      121 acttgtggtc gttccgtgaa gttcttggta cgtttgcgtt ttataaagat caacagttga
      181 ttgtccgttg tgttcactaa agacactagt tgacttgtca ccaagagatt tttcagcttc
      241 ttttaatttc tctaagccat tcttgtagtc ataatcactg gtatcaattg ggtctaatcc
      301 actattcgta tagaaccgaa gaagatcacc attattgatt tggtcagaaa cagctaactg
      361 tttatcaact ttttctttca gtgaatcaat ttcattctgt acttcctcag taggttcagt
      421 aatagcttca ccagtttcgt tactatagat cgtaccaccg tagtaagtat attttggtgt
      481 aacaaaatca ccatcacgga aagaaacaag ctgttcatga tctttcgaga atagatcttg
      541 tcctaactga atataatttt ttgtatctac acctagtaag tgaagtaatg taggcaaggc
      601 atcaacttgt ccgccgtaag tgtgattgat tccgccctgt gtttgtccag ggatatggat
      661 catataaggg acacgctgca tttgtgcatt gtcgtagttt gtccaagtag aacttgtttt
      721 tccaactaat tcagctagat ttttatttct tgaattcgag acaccgtaat ggtcaccgta
      781 aaggacgatg actgaattat catacaagcc gctttctttc aaataattga agaattcttg
      841 tacggcggta tctaaataat tggctgtcgc aaagtaaccg ttgatcgttt catcatttgt
      901 attggctaac gggaatcctg cttcgtcatt ggtgaatttt gaataaggat aatggttaga
      961 tacagcaatg aattttgaat aaaatggttg ttgcagacgt tccaagtatt gtacggattg
     1021 ttggaaaaat ggtttatcat gcaacccgta ttggaacgaa ttgtcatcat taacatcata
     1081 ataagaagaa tcaaagaaat aatcatatcc taaattcttg tatgtctcgt ttcgattcca
     1141 gaatgtacca gcgttcccat ggaataccgc actagtgtaa ccttgtgttt gacttaaaat
     1201 atcaggtgca gcttggaaag tattttttcc gcctaattgt gtgaacaagg agccttgatt
     1261 caagccaaac aatgaatttt ccatcagcgt ttccgcatcg cttgtttttc ctgcttttac
     1321 ttgatggaaa aagttgtcaa aactgaacgt gctgttgctg tggtaaagac tattgatgaa
     1381 aggtgtaact tcatgctgga gaccattctc atctgtcaat ttataatcga tcaggaattg
     1441 ctggaagctt tctaaatgga tataaatcac attttttcct ctagcgagcc cgaacaaatc
     1501 gtcatttggt gctgcataat gttcttttac ataattttct acttctttca tatcattggg
     1561 acttgcttct gcccgcactt ggtttgtctg gtaagtttga acaccgtcat aaaccatgaa
     1621 agcattcaag ccaagatatt tgaccaaata atcacgagag aatgttcgag tcagcaattc
     1681 tggacgatca gcttccgcca taaaaagatt tcctgagaaa atcataactg ctaatgtaga
     1741 gatcgcaaaa gccattcttg ctcggatcgg gcgagggtcc aacttgattt tttttgcaat
     1801 cagcagaaca gtcaagataa taaaatcgat ccaatagatc acatcatatg ggcgaaacag
     1861 tcgaatggca ctttctccca gaccactcgc tactttccca gcacctaaaa tcgtgttgat
     1921 cgtaatgaag tccgtgaatt ctcgataata agtgacattc gaaaaaacaa gcaatgtcaa
     1981 aagaaaataa atgaccatca tcgtgatata agcaactcta gggcgtctga tataaagagc
     2041 aattccaagt aataacaatg tagttgcaat agggttgata aacaagataa agtattgaat
     2101 gccactttcg attccgagat ggaaatcaac taaataggca aaaatcgttt tcaaccaaag
     2161 taaaacgact agtaaagaaa aaaatccgag cctcttattc aaaaaggcag gtgtttttat
     2221 acatttcaag ataatcttcc tttctgcact tcttaatcac agaagtgtcc tgaaaccatg
     2281 ttacacagct cacttattct catttatttt actagtatga caatatagtg tcaattgaaa
     2341 ccagaagttt atgctgtttc attaaggttt tctttaagct tcatgaaaaa atgagcagta
     2401 agacaagtcc tatgtttttt gttatacttg ggaagagaaa gctaaagcag gtgaaggaat
     2461 gaaagtaaaa gtaaaaaaaa gagcaagcaa tcgattgaaa aaaggatatc cactgatcca
     2521 aaaagaagac cttgctcatc cccaaaaaga aaccacgcaa tgggtggaat tagttgattc
     2581 gcaaaaccaa tttatcgcaa aaggatatct aggaaagcag aataagggaa tcggttgggt
     2641 attgagccag cagaacatcc catttgatca atcttttttt gaagaatttt ttgtgaagtc
     2701 aaaagaaaaa agaactttct ttttttcaga tgattctact accgcttttc gtatattcaa
     2761 tggagaagga gacgggatcg gcggtctgat tgttgattat tatgcaggtt atgctgtttt
     2821 ttcttggtat aacgaaacgt tatatgcaca tcgtgaatta ttgattcaag cttttcgtga
     2881 aatctacccg gaaatcatag gaggctatga gaaaattcga tttgaatcag taaatctgcc
     2941 tgagagccag ttcatttacg gaaaagaggc accggaaccc ttgatcgtaa aagaaaacgg
     3001 agtaaaattt gccgtttatt taaatgaagg attaatgact gggatctttt tagaccaaaa
     3061 agaagtacgg ggatcattag cagaaggttt cgcttctggg aaaacagttt tgaacatgtt
     3121 tagttatacc ggcgcctttt ctgttgctgc cgcaatggga ggggcaatcg aaacaacaag
     3181 tgtcgatcta gcaaaacgca gtttaaaaaa aacacaggaa cagtttgaag tgaatggttt
     3241 ggatgtcgat cagcaaaaaa tcattgttat ggacgtattc gagtatttca aatacgccaa
     3301 aagaaaacaa tttttatatg acatgattgt attggatcca ccaagttttg ccagaaataa
     3361 gaaaaaagtc tttcgcgtag caaaagatta tggggaactg gtcaaggata gtctggatat
     3421 tttagcagaa gacgggatac ttattgcgtc tacaaatgct gcgaatgtct cgatagaaca
     3481 attccaaaca atgattgaag aggaattcca tgccaaaaat gtttcttttg aacaacttgc
     3541 tttatatcgt ctgccaaaag atttccagac gacggatacc tttttagaag gcaattatct
     3601 gaaagtgttt gtttatcaaa ttaaaaataa ccattagaag gagcgatgca gaatggttcg
     3661 ggtaaaggga ttgaatatag gaagcggtag accaaagatt tgtgcgcctc ttatcggggc
     3721 cgtccgagag gaagtattac gtgaagcagt tcttgcacgt gaagcagggg ccgatttagt
     3781 cgaatggcga gtcgatcatt atcgtgaagt tttttctttt gatgaagtag cagaaacatt
     3841 ggttcttatc catgagatgc ttgatggact gccgttatta tttacgtttc gtaccttagc
     3901 tgaaggcgga gaacaagaca tatcgatccg tcagtatcgc gacctttatg aacatgtgat
     3961 acacacagga ttagtagata tggtcgatat cgagttgttc aaagtagaaa gtctaggaaa
     4021 aagactgata gaggaaatca agtctttaaa cattccttta attatcagta gtcatgattt
     4081 taaagaaaca ccagcagacc ctgtcttgct ttaccgattg aatgttatgg aacattttgg
     4141 agccgatatc ggaaaactgg cagtaactcc caataatgaa cgagatgttt tgcggttgat
     4201 ggagttgact agacgggcaa atgcttttgt ctccatgcct attattacga tgtccatggg
     4261 aaatcttggt aaaatttctc gtctggttgg cggaacgacg ggttccgtta tgacatttgg
     4321 ttccttaagc agcgattcta cttctgctcc aggacaatta ccggtcaaag cattgaagca
     4381 aattattcaa ttattaaatg aaccgttgta gaacaagttt gaggtgatat tttttggcaa
     4441 agaaaaaaat agtaaaaacg aatgcaatcc gtatggtcga acaaaaaaag attccctata
     4501 cagagcacga atatgagtgg gacgaaagcc acctaagtgc gtcatcggtc gctgaacagc
     4561 ttccagaaag ccaatctcgt atatttaaaa cactggttgc tgtgggcaat gtgacggggc
     4621 ctcttgttgc tgtgataccg ggagaagccg aattgaatct aaaaaaatta gcaaaagttt
     4681 cagggaataa aaaagtagaa atgctccatt taaaagattt ggaagcaacg accggataca
     4741 tacgtggtgg ctgctcgcct ataggtatga aaaaactatt tcctacttat ttagatcaaa
     4801 ttgcagaaag ctatgaacaa atcattgtct cggctggcag aagagggcta cagatggagt
     4861 tagcacctca agatatctgt gcattaacga gcggacaatt tgcagatata aaacaataaa
     4921 tcatacgtat aaaagaaaga aggaggccgg gatgttgttt gtccagtctc cttctttctt
     4981 ttttatacat tatgctcttt gcccggcatt cattcctgct acatgccctg tagcgaaagc
     5041 cgctgtgata ttaaagccgc cagtataacc attgacatcc agtaattctc ccgcaaaata
     5101 cagaccatca atgattttac tctccaatgt tttaggataa atttccttta gagaaacccc
     5161 tccgccagtt acaaatgatt tctcaatagg aaaagttttg ttgattgata gcttaaactc
     5221 tttgcatagt tgaacaaaat cttgaatttg tttttgagag gcttgttgtc ctgtcagatg
     5281 atccatttca agccgctcaa gaaagaaaac taacaatcgc tcaggcaata taccatgcca
     5341 agcattgacc aagttctttt tggttgcttt acttttttct gtcaatatat gaataagctc
     5401 ttgtttggtt tgtgtaggga aacaatccag agaaagtgtc actggttctc ccgttttctc
     5461 taattcttta ttgacaaaac ttgaacaacg cagtgcagcc ggaccagaaa taccgaaatg
     5521 ggtgaaaagt aaatccatcg tatgttcagt caatacacga ccttttttat ttaaaacgcg
     5581 taaagtgatg tcttgtaaag aaagcccttg aagtgttttc tcctgaatat acggttcatc
     5641 cgatatcaag ggggactctg tcgcataaag aggcgtcacc gtgtgaccca ctcgcttcac
     5701 gatcttgtac ccatctccag tagaaccagt agatggataa gtccgtccac cagttgttaa
     5761 gataatggca ggagcatgga actcttcgaa ttccgtgcgt ataccgtaaa ttttatgttc
     5821 tttgtggatc aatttctcta ctcgagtaga gaatagaagc gtcacatcta gttctttcag
     5881 acgattgagc aatgcttcga taatcgtttt tgatttattt gttacaggaa acatccgtcc
     5941 atgatcctct tcttttaaat gtacgccttg tgattcaaag aagttcatga tatcgaaatt
     6001 attccattgc gcaaacgtac tatataaaaa ctttccattt ccaggaatat gtgcaatcaa
     6061 atcatcaaca ggacgattgt tcgtaacatt gcaccgacca ccacctgtca tcagtagttt
     6121 ttttcctgct tttttgtttt tttcgatcaa gagtacgcgt gcgccttgtt cagctgcact
     6181 gatcgctgcc atcatcccgc ttgttccagc gccgactacg atcacatcat acagtttttc
     6241 cattccctca cctcaaggaa agtgtagcat atctgaagaa agaaaacaga aaaaaatgtt
     6301 ttgagccaaa agagaaaatg agctaaaatg agggaagata agcaaaggag cgtggaacga
     6361 tgacaaacgc aacagaatat gttcaagcaa ttcaagaaaa gctacatcaa aaggatcaag
     6421 ggcaagaaga atttttacaa gcaatcgatg aattcatgcc cacggttatg tcttttttgg
     6481 acactcatcc cgaatatatc gaaaagaata tcttagaact tttaacggaa ccagaaagag
     6541 ttattcaatt tcgagtgcct tggcaagatg atgaaggaaa ctggcgagta aatagagggt
     6601 accgtatcca atacaactca gctatcggcc cttataaagg tggattgcgc ttccatccta
     6661 gtgtcaatct aagtatcttg aaatttttgg cttttgaaca gattttcaag aatagtttaa
     6721 ccggtctgcc aatcggtgga ggaaaaggcg gaagtgactt cgatcctaaa ggaaaatctg
     6781 ataatgagat catgcgtttt tgtcaaagtt tcatgctgga attgtcaaaa catatcggcc
     6841 catcgattga tgttcctgcg ggagatatcg gtgtaggagc tagagaaatc ggctatttgt
     6901 tcggcgaata taaacgattg aaaaaatatg atactggtgt gttgacaggt aaacctttgg
     6961 atttttgggg aagtaagata cgtacggaag ctactggtta tggattagtg tattatgtca
     7021 aacatctatt gaacgaagaa aaagattcat ttaatcaaaa aacagttttt gtttccggaa
     7081 gcgggaatgt agccatttat gcaatcgaaa aagtgcaaga gctaggcggg aaagttgtta
     7141 catgttcaga ttctagcggg tacatctatg atccagaagg aatagatgtg aaactattga
     7201 aagaagtcaa agaaatcaat agacaacgtt tgacggaata cgcaaaccaa cgtccttctg
     7261 ctatttatca tgctggagaa tctgtttgga cattgaaaga aaaagcggat atcgctttgc
     7321 catgtgctac tcaaaatgaa atagacgaaa gcttggccga aatcttagta gaaaatggga
     7381 tcaaaatcgt agcagaaggc gctaatatgc catgtacagt aaaagctgtt tctgttcttc
     7441 atgaagcagg cgtgtggtat tgtccaggaa aagctgctaa tgctggagga gtagcagtat
     7501 ctgctttaga aatgagtcag aacgtccagc gattgacttg ggaaagagag caagtggatg
     7561 agcagctgga tcaaatcatg gaaacgattt accatacgtg tcgccaaaca gcagccgagt
     7621 acggcgacga aaaaaatctg cttcttggag caaatgttgc tggatttgaa aaagttgcca
     7681 aagcaatggc agcagaaggt ttagtttgaa aaatgaaact ttcttggaaa tattgtcagc
     7741 attttgttta tttgcttgaa aaataataaa aaaaaacgta aagtattacc tgtagagtaa
     7801 acctataagg aggagaacaa atggcacaca ttcattttga ctattcaaaa gtagcaccgt
     7861 ttgtcaacga acaagagtta gggtacatgc aaagccaagt aacagcagcc cacaacgaat
     7921 tacgggaagg tactggcgca ggaagcgact tccgcggctg gatcgattta ccaacgaact
     7981 atgacaaaga agaatttgca cgtatcaaag aagcagctaa aaaaatccaa tctgattctg
     8041 aagtattagt tgttatcggt atcggtggtt cttatttagg cgctcgtgca gcgatcgact
     8101 tcttgaatca cacattcttc aatttattag atagcaacac aagaaaagca ccacaaatct
     8161 tctttgccgg aaattcaatc agctcaacat atattgctga cttgatcgaa gtaatcggtg
     8221 atcgcgactt ttcagtaaac gttatttcaa aatctggaac aactactgaa ccagcgattg
     8281 cgttccgtgt attcaaagag cttcttgtta agaaatatgg acaagaagaa gcaaacaaac
     8341 gtatctacgc tacaacagat aaagcaaaag gtgcagttaa agtagaagca gatgcagaag
     8401 gttgggaaac tttcgtgatt cctgatgaca tcggcggacg tttctctgta ttaactgctg
     8461 ttggtttgtt accaatcgct gttagtggtg cagatatcga tgcattgatg caaggtgccg
     8521 ctgatgcaag caaagcatac tcaagcgaca aactagaaga aaacgaagct taccaatacg
     8581 cagcaatgcg caacattctt taccgtaaag gcaaagtaac tgagttgttg atcaactatg
     8641 aaccaggaat gcaatacttc tcagaatggt ggaaacaatt gtatggtgaa tctgaaggaa
     8701 aagaccaaaa aggcatctat ccttcaagcg caaacttctc aactgatttg cactctttag
     8761 gacaattcat ccaagaagga cgtcgcaata tttttgaaac agttgtgaag gttgaaaaac
     8821 ctcgtaaatc aatcacaatt cctgaacaag cagaagattt agacggtcta ggctacttgc
     8881 aaggaaaaga agtggacttc gtaaatacaa aagcatttga aggaacattg cttgctcata
     8941 cagacggtga cgtgcctaac ttgctagtca aaattccaga aatggatgct tatacattgg
     9001 gttatacaat gtacttcttt gaaattgctg taggtatttc aggttacttg aatggaatca
     9061 acccattcga ccaaccaggt gtagaagctt acaagaaaaa catgttcgca cttctaggca
     9121 aaccaggctt tgaagatctt gctaaagaat tgaacgaacg cctgtaagat aagggttttt
     9181 cgctagattt aaataatcag tgatagaaac atgttcgctt taaaatgaaa actggtaccc
     9241 atttaggtac tcaaacatac tgcatcgttt attcagaata aggggctgtg acaagacgtt
     9301 tgtcacagtc ccttgtttgt atagaaatcg attgattgcc ttgctcttta gtttgtttta
     9361 ggactttaag aacagtgagg ctgacttcga aggttaattc tgtttttttg ttttctagaa
     9421 tcagtaagca aaaaagcact cacttcgagt gcttttttgc gatatattct tagcttaaga
     9481 taggcctaat ttttctttta cagatgaggg taccttatcg ctggtaatta cttttttctc
     9541 tatgatccgc ttttcgcttg ctttcaactg caagatcgtt ccttcggggt aagcagaacc
     9601 attggcagag tcaccagaag taatgacatc gaaatctaac tgtctttttt caccgttttc
     9661 agcataagca tctacgttgt atttaaaacc tcttccaatt acttccccat tatctgcttt
     9721 gatatcagtt tctgcaggca ttggagcttt gactaccgca taataatctt tacctacata
     9781 agtagactga tagtagtccc aacctttcca tcctataaaa gcaatcaata tgataacgat
     9841 caaccctaaa atttttttca tgaaagatct ccttttttat ttttat
//
LOCUS       DADQDV010000089         9869 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.092, whole genome shotgun sequence.
ACCESSION   DADQDV010000089 DADQDV010000000
VERSION     DADQDV010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9869)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9869)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9869
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.092"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(18..263)
                     /locus_tag="J8S10_002571"
     CDS             complement(18..263)
                     /locus_tag="J8S10_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631135.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(377..955)
                     /locus_tag="J8S10_002572"
     CDS             complement(377..955)
                     /locus_tag="J8S10_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAZ9631136.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSIISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(1032..1562)
                     /locus_tag="J8S10_002573"
     CDS             complement(1032..1562)
                     /locus_tag="J8S10_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HAZ9631137.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(1566..2426)
                     /gene="rlmB"
                     /locus_tag="J8S10_002574"
     CDS             complement(1566..2426)
                     /gene="rlmB"
                     /locus_tag="J8S10_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HAZ9631138.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(2419..2814)
                     /locus_tag="J8S10_002575"
     CDS             complement(2419..2814)
                     /locus_tag="J8S10_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HAZ9631139.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(2811..4223)
                     /locus_tag="J8S10_002576"
     CDS             complement(2811..4223)
                     /locus_tag="J8S10_002576"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HAZ9631140.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(4220..4756)
                     /gene="cysE"
                     /locus_tag="J8S10_002577"
     CDS             complement(4220..4756)
                     /gene="cysE"
                     /locus_tag="J8S10_002577"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HAZ9631141.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     gene            complement(5078..6538)
                     /locus_tag="J8S10_002578"
     CDS             complement(5078..6538)
                     /locus_tag="J8S10_002578"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HAZ9631142.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(6708..7865)
                     /locus_tag="J8S10_002579"
     CDS             complement(6708..7865)
                     /locus_tag="J8S10_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HAZ9631143.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(7899..9269)
                     /gene="radA"
                     /locus_tag="J8S10_002580"
     CDS             complement(7899..9269)
                     /gene="radA"
                     /locus_tag="J8S10_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HAZ9631144.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKIAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(9332..9859)
                     /locus_tag="J8S10_002581"
     CDS             complement(9332..9859)
                     /locus_tag="J8S10_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HAZ9631145.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
BASE COUNT         2506 a         2213 c         1784 g         3366 t
ORIGIN      
        1 tcaggctcgt ttgcttttta aactgcttca gttaaaaatt cgatctcaac tgtccgagta
       61 agtacatctg aatagctgta agatactcgt tcaaaagaat tttcttcagg atccaaatca
      121 acaacgaata ctgaaggata ggtttctgtt aaaacgccgc ggcgttctgt ttgacgcttt
      181 cttcctgtct gagcaaccaa catgattggg ctgccgatac gaccttctaa atctttcttg
      241 attgaagcta aagttgttgg catacagttc acctctacta tcaactatac cacatatttt
      301 taaaattttc aagtttacca taaaaaaaaa gaaatgcaat aaaaataaat aagaagctca
      361 ttaagatttt tctaaattat tcctcattat aaaatttcaa gtgttttttt attttgagtt
      421 ttactctccc gtaagcgctc attacttgct tgtgatccat tgctaaacat tcagccatgt
      481 ctacaaaatc aacgccttgc atataataat gaaaaatttt agcttctatt tttgaaaact
      541 ggatttcgca attttcgatt gcttctttta ataaaagatg ctgaatcgct aaaggttctt
      601 gcaatgtgat ctctgctaaa aagtctggtc cttctgtctc tattttttgg tcgattgaga
      661 cttcatcttt ttgatcacga cgcttcagcg cgttctgctt cctcaacaga gaatagattt
      721 gattgcttat aatgctttta taataacttc caaagctaac acctttgctt ttttcgtaag
      781 ttctcaatgc ctgatataaa gcgatccttg cttcttgttc ccaatcctca gaaacataat
      841 ttcttaaata ataggtgttt ttcaaacgta gtaaaagtgg aaaatatttt tgatacaggg
      901 cagcaaatgc ttcttcgtca ccattacgtg cagcgcgcaa taactcctca gacataaaat
      961 aattcctcca taaattcgtt tatggaggaa tcttatcatc aatgattcat cgaactgatt
     1021 agaacgatat gttatttatt ttttctcatt aaatcgtcca atttttggga caattttttt
     1081 aactgctctt cattccatgg agaattacgt cggaaatcaa taaaatgcat atctttattt
     1141 tcttgggcta ttgttttttc cgtttttttt atcgtcttat ataattcata agcagaagtt
     1201 cgtaatgctc cttgggaaaa gatcatccac tgttctgcta aatcgcttgt cgccactgtc
     1261 acttgtgtca aacggtcatt cagctgacca gcgattctct cgatataact gtcagccgtt
     1321 tcgtcttctt tcgtaaaaac aacatccaac tggtatttct tataattttg ttggatgccc
     1381 ggaactagtt gggcatcgaa gacaacgatg acttccattc cttcatattt cgcataattt
     1441 gataaacgat gtaaaagagc ttctcttgca tccgccattt tgtcctgctt tttaagctgg
     1501 acaagttccg gccacgaacc aatcatgttg tagccgtcta caatcaacag ctgttttttc
     1561 atggtctact ccccctgacg ttgggaaaaa gcctgataca taagcaaacc agcagcaaca
     1621 ctggcattta agctctggac gtgcccggtc atcgggatcg tcagcaattc atccatttct
     1681 tttttcaatc ctggactcat tcctttgcct tcattaccaa tgactaaagc aattgatcct
     1741 ttggcattcc atttttggaa gtttgtgccg gtcatatctg tgccaaatac ccaaaatcct
     1801 gtttctttga gctgttgcac agcttgtacc aaattcgtca cgcgtgcaac agggacatgt
     1861 tcgactgccc cagtggaagt ctttgttacg ataggtgtga ttccaactgc tcggtgtttt
     1921 ggtatgatca caccatcgac gccacttgcg tctgctgtcc gtaaaatcga cccaaaattg
     1981 tgtggatctt cgatgctatc caaaatcaaa aagaaggggt cttctttttt ctcttttgtt
     2041 cgttcaatca gttggtcaag ggataaatat tcataaggtg taatcgcaag aacgactcct
     2101 tgatgcacgc cgtgatcgct caaagtttct aatttttgtt taggaaccca tttgactggc
     2161 acagcttgtt cacgtgcgat ttctttcagt tcttctactt tttctcctcg tgaatcttct
     2221 tgaagaaaga gtttattccc tcgcccttgt tgtagcgctt ctactgcggc atggtgccca
     2281 aagacgaaat tatcttctaa tgcttcttca ttttgatcag aaactgactg atttcgtcca
     2341 gtttgctttt tatttgaata tctattttgt tttttgtctt caaatccacg tttcgattga
     2401 tgtttgtttg ttctttcttt acccattttt ttcaccaact ttctgaatac accagcggat
     2461 caattcttcc atccgctcgg tttgttttgt caaatgcaga tagcccatga gcgcttcgaa
     2521 ccctgttgcg acccgatacg tcgtaacatc agcatttttt gcgctcgtat ggcttttagc
     2581 atttcttcct ctgcgataat aaagttcttc ttcttctgtc aaaagatgtt cttccagcat
     2641 ttgctgaatc aaaaaggctt gtgcattcgc agaaacataa ttcgttgccg cacgatgcag
     2701 cttattgggt tttgtttctc cttgatcaat caggtggtca cgaacataga tttcgtaaat
     2761 cgcatctcca acataagcca aggctaaacc gttcaattgt gtgtaatctc tcatgcttct
     2821 cttctccatc gggttccttg cggtgtatct tctaataaga tccctttttc tttcaacaaa
     2881 tcacgaattt cgtcgcttcg gacaaaatca cgattgcttc ttgcttgatt tcgttcttcg
     2941 atcaattgtt caatctcttc atctaataac tcttctgctg taaataaaat accgaagatc
     3001 gaaagccatt gcgagaataa agcttctcct tgtgccaaga cagcggcaga aactttcggc
     3061 tggtctagat aagtgttcag ccacttagca agctcataga ccactgtgat cccatttgct
     3121 gcattaaaat catcgtccat ttcttcgatg aatcgctgtt ctaaattttc taacaaagcg
     3181 attttatccg catcatctgc caaattctct gaggcagttt cttggcggaa tttcaaattg
     3241 tcaaacgtat tcttcagtcg ttgtaaattg gtggctgctt ctttcatcgt cgtttcactg
     3301 tagcggatcg gacgacggta ttgtgtggtc gccatgaaga aacgcaagac ttgtggatca
     3361 acgtttttga tcatttcatg tacagtgatg aaattcccta gagatttact cattttttca
     3421 tcgtcttcgc caatcgttac atagccattg tgcatccagt aattagcgaa ttttttccct
     3481 gttttcgctt cactttgtgc gatttcattt tcatgatgag gaaattctaa atcttgcccg
     3541 ccaccatgga tatcgatcgt ttctcctaaa tgttttgttg ccataacgga acattcaata
     3601 tgccaaccgg gacgtccttt gccccatggt gaatcccaag aaatctcgcc aggttttgct
     3661 tgtttccata aagcgaaatc taatgggtct tctttttgct gctgttcttc ccctgtacgc
     3721 tgacttgctc cgacttccag ttcatcgatg gattggtcac ttaatttccc ataattttca
     3781 aatttacggg tacggtaata cacatcacct gaagattcat aagcatagcc tttttcaacc
     3841 aacacttgaa taaatgctaa aatatctggc atatgatcca tgactcttgg atgcagtgta
     3901 gcaggctcga cattcaacgc tttcgtatct tcttcaaatg ctcggatgaa acgatcagca
     3961 acttctggtg ctgtaatacc taattcgttt gctgtacgga tgattttatc gtctacatcc
     4021 gtgaaattcg atacgaaatc gactttatag cctcgatatt caaaatagcg tcgaattgta
     4081 tcgaaagcaa tggtgctacg agcatttccg atatggatat aattatacac agtcggtccg
     4141 cagacataca taccgacatg tcccttttgt atagggatga attcttcttt ttttctggtc
     4201 aatgtattgt agatttttat cattctgatc tcctcacttt ttctcctttg attcgaacga
     4261 cttttgctgg tactcctacc gctgtagcgt cgtctggaac atctttcaac acaacggcac
     4321 ctgcaccgat tttggcgttt tttccgatcg ttaccggtcc taatatctgc gcattcgcag
     4381 agagcatggc tccttgttta acagttgggt gtcttttacc cgtttctttt cctgtgccgc
     4441 ctaatgttac gccatggaat aaaatcacat cgtcctcgat ttctgcggtt tcgccaatga
     4501 cgattcccat tccatggtcg atgaacacgc cagttccaat cgttgctcct ggatggatct
     4561 caacaccagt taggaaacgc cagaattgag cattgatctt cgccaataaa aagagccggt
     4621 gctgatataa aaaatgagag aaacgatgcc aaaacaaggc atgaaaacca gggtatgtca
     4681 aaacgatctc agctgtcgaa cgtgcagccg gatcgtttct ctttgctgca tcaatcgctc
     4741 gggtaaacca actcatgact ttccactcct ttcgtaagaa ttttatgtag gaaatcatct
     4801 tcttataaag aaaagaagcg ccttttaaat aagtttcctt atcaaaagac gctttccgcg
     4861 tggttccact tttcttcata atcaatgatt atctctgaca gctaacgcct gttatacgtt
     4921 cttggctact ttgtttccta taaaacagtt tttcctgttt tctgtgtttc gccaagacca
     4981 ctcccagagg catttcggca accattcatt gataccttgc accacccggt atctctcttg
     5041 taatgatcag ctgcttactt ttttctgttc atcgtgttta gttcagtact tgatttaaat
     5101 gtgctaatga tttttcacga ccaagcaatt cgatcgtttc aggcaattct ggaccatgca
     5161 tttgtcctga tacagctaca cggattggca tgaaaagatt ttttcctttt acgccagttt
     5221 ctttttgaac agctttgatg gcagctttga cagttggagc atctactact tccatttgtt
     5281 ctagctgtgc tttgaatgcg tggagaacag taggaactgt ttcaccagca agtacttctt
     5341 ttgctgcttc attcaataca ggatgttcat tgaaaaatag cgtagacaga tcaacgattt
     5401 ctgcagcata gctcatttga ggttgataca ggctaacgat cttcttcacc cattcgattg
     5461 tcttttcatc tgggttttct gctacacgtc catcagcgat tagataaggc agacacatgt
     5521 cagtaaatgc atctagatcc attgctttga tgtaatggtt gtttacccat tgcagttttt
     5581 tcgcatcgaa agctgcgggt gatttactta ggcgttttgg atcgaacatt ttgatcaatt
     5641 cttggtgttc gaagatttcg tcttcgccca caggtgacca gcccaataat gcaataaagt
     5701 tgaacattgc atctggtaga tagcctaatt cgcgatattg ttcgataaat tgcaagattg
     5761 attcgtcacg tttgcttagt tttttacctg tttcactgtt gatgatcaat gtcatatgtc
     5821 cgaaggttgg tggtgtccag ccaaatgctt catagatcat cagttgtttt ggtgtattgg
     5881 caatatggtc atctccacgt aaaacgtgag tgattttcat caaatgatca tcgaccgcaa
     5941 cagcaaaatt ataagttggc ataccatcgc gtttttgtat gacaaagtcg ccaccgatat
     6001 tatcggattc gaacgaaata gcgcctttca ccatatctgt aaatgcgtat tctgtattgc
     6061 gaggcacacg gaaacgtaca acagattcta gaccttgtgc ttctttttct gcttgttctt
     6121 caggtgtcaa gttcgcacat gttcctgcgt aatgaggcat ttctcctctt gcgcgttgtg
     6181 cttcccgttc tgcttctaat tcttcttctg tgcaatagca tttgtatgct cgattgctag
     6241 caagcagctg atcaatcagc ggttgataga tttctttacg ttcagattga cggtaagggc
     6301 cgtattctcc aggattttca ggagattcat cccaattcat tcccaaccaa gcaaggtttt
     6361 ccaactggct tttttcgcca tcttcgatat tacgtttttg gtcagtatcc tcaatacgaa
     6421 taataaagtc tccatcattg tggcgggcaa acaaataatt gaataatgca gttcttgcat
     6481 ttccaatatg caggtgccca gttggacttg gtgcatagcg tacgcgtact ttcgtcattt
     6541 tcttcctctt ctttcaaact agactttgac taacagcaaa aattccgtca gttacggctt
     6601 ctcaaatatc atttatttaa agccactcag cacaaatttt accttttcta aggtaaatag
     6661 taaagccaac tggttgaatt tccttaccag ttggctgaat ttctttttta ttttgattgt
     6721 ttagtctttt tctctgtctc ttttttattg tcgattcctc gtcctgcatg tgcaggttta
     6781 gcaaagatca tgcgtccagc agctgtttga agggcacttg ttacaacgac ttcgatacgt
     6841 tcattcatgt aatgctgtcc atcttctacg acaaccatcg tgccgtcatc aaggtaggct
     6901 actccttgtt ggcgttctgt cccggctttt actactagaa cattcatcgt ttcaccaggg
     6961 atgacgactg gttttacggc atttgccaac gcattgatat taagaacagg tacattttgg
     7021 aattcagaga ctttattcaa gttatagtca ttggttacaa tgacaccatc taaaagctta
     7081 gccaatttga tcaatttgct gtctacttca ctgatatctt caaagtctcc atcgtacatt
     7141 tcgacagata taccctcttc tttttgcaag gcatttagga tatctaatcc gcgacgacca
     7201 cgcacacgtt tcaaactatc ccctgagtcc gcgatgtatt gtagttcgta aagaacaaaa
     7261 ttagggatca tcaaggttcc ttctaagaat ccagtctttg taatatcata aatccgaccg
     7321 tcaatgatca cgcttgtatc caagatttta tatttatgga aattttctcc tgattttcgt
     7381 tctaacagtt gactctcaac ttgactagct gtttcttgct cgattttttt gcttcgtgaa
     7441 ccaaaaactt tcttccattc ttcgattcgt gtcgttccca ttctcaatcc cagatagcct
     7501 aagatgatca tcagtaaaat cggcaataca ctattgacga atggaatttc catattgtaa
     7561 agaggggtcg agatcacaac acctaaagtc aatccgatga tcgcaccgat cgcaccgaag
     7621 agaagataag tcaagctgac ctcacttagt ttttgttcta cttgtttgat aatagctgag
     7681 atatgtttgg ccaacagcaa agataataaa aagaaaataa gtgcgcctaa caggctgttg
     7741 gtaaatgtat tattcagcca tccgtttgac tgttgaccga ttgcctgcca agctgagggt
     7801 aaaaatgaaa tacccaagct tgcgccgaca atgatcatca gcaaagtaat gacacgtttt
     7861 tgcatcgttt ttcctccgtt tcgacaatca tttattagtt agcggaacac acgcttcaac
     7921 gtttcagcca aagttgctac tccaactatc tcgattcctt ttggcgcttc ccagttacct
     7981 aagttgtttt taggtaggta tacttttgtg aagccgagtt tttggacttc tttgactcgt
     8041 tgttcaatat gactgacacg tctgatttct ccagtcagtc caatttcacc gatgaaacat
     8101 tccgttggct gtgttccttt ttctttatag cttgaagcaa tactgacagc gatagctaaa
     8161 tcaatcgctg gttcatttaa ttttacccca cctgcagctt ttaagtaagc atcttgattc
     8221 tgaagaagca acccagctct tttttccagc actgccatga tcagagatac ccgattgaaa
     8281 tcaagacctg ttgttgttcg tttggcattt ccgaacatag taggtgtgac taatgcttgg
     8341 atctctacca aaattggacg tgtcccttcc attgccacaa cgatagcaga gccagttgca
     8401 ccgtctaggc gttcttctaa gaaaatctgt gaaggattag cgacttcttc caatccatgc
     8461 tcatgcattt caaaaatccc aatctcattc gttgagccaa atcggttttt tactgctcgc
     8521 aaaatccgaa aactatgatg ttgttcacct tcaaaatata acaccgtatc caccatatgt
     8581 tctaacattc ttgggccggc gatcgagcct tctttggtaa catgaccgac gataaaaatg
     8641 gctatcccat ttgttttagc gattttgagt agttctgcag tggtttctct tacttggctg
     8701 acacttcctg ccacacttgt gatgtctggc tgcgtcatcg tttggatgga atcaatgata
     8761 acataatcag gggagatatg ttcgatggca cgactgattt cgttcatatc tgtttcagcg
     8821 tatagataaa attctgtgtt gatacttccg aggcgttccg cgcgtaattt tatctgctct
     8881 gcgctttctt cgccggatac atataagact tttccgccta tggctgctaa ttgctgagaa
     8941 acttgtaaca gcaaagtgga tttcccgata cctggatcgc caccaatcaa gaccatagac
     9001 cctggcacca cacctccgcc taacacacgg ttcagttctt ctaattttgt tttgatccga
     9061 ggttcttttt tagggacgac gtctgcgatt tttgttggtt ttgctttttc tcctgtcaaa
     9121 cttgtccgag ttctgcggtc cgttgtatct tgttcgattt cttcgaccat cgtattccat
     9181 tttccgcaat ttgggcagcg tcccaagaac ttaggcgaca catacccgca attttggcaa
     9241 acaaattgta cttttgattt ttttgccatt gtaccgcctc cttttatcct aatcatgaga
     9301 cattaaatca agcttaagta tctttaacgt tttatttact ggaagaacca aatccgcctt
     9361 gacgttgagc agtcgtttga tcttgatctg cttttaaaaa cggcaaaaag atcccttggc
     9421 cgatacgctc gccttttttg atcactacat ccttgaaacc aaagttggtg aattggaaca
     9481 tgatatggcc ttcatttgcc tcattattgt aataatcact gtcaatcaca cctactccgt
     9541 ttgtcaacac taaaaaccgc ttcaacggat tgcttgaacg gttagcaagc tgcaaaaatt
     9601 catcttctcc catgtaagct ttgattccag taggcacgag ggttggtttc aattgttttt
     9661 cattttctga tacatctttt ttcaatccat ctgcgactgt ttccaacccc tttttccagc
     9721 ctgctttcca gatacttgga atcacgacct cttctgctgc ttcaaaatca tagccagcag
     9781 catgatgtgt agcgcgctgc ggtagattga tattttgatc tttatattta gaaataactt
     9841 caaatcctct ttttctcacc ggttttcct
//
LOCUS       DADQDV010000090         9466 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.093, whole genome shotgun sequence.
ACCESSION   DADQDV010000090 DADQDV010000000
VERSION     DADQDV010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9466
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.093"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            90..1349
                     /gene="lysA"
                     /locus_tag="J8S10_002582"
     CDS             90..1349
                     /gene="lysA"
                     /locus_tag="J8S10_002582"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HAZ9631146.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            1336..2136
                     /gene="dapF"
                     /locus_tag="J8S10_002583"
     CDS             1336..2136
                     /gene="dapF"
                     /locus_tag="J8S10_002583"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HAZ9631147.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            2139..3020
                     /locus_tag="J8S10_002584"
     CDS             2139..3020
                     /locus_tag="J8S10_002584"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HAZ9631148.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            3017..3733
                     /locus_tag="J8S10_002585"
     CDS             3017..3733
                     /locus_tag="J8S10_002585"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HAZ9631149.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            3739..4434
                     /gene="dapD"
                     /locus_tag="J8S10_002586"
     CDS             3739..4434
                     /gene="dapD"
                     /locus_tag="J8S10_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HAZ9631150.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            4450..5451
                     /locus_tag="J8S10_002587"
     CDS             4450..5451
                     /locus_tag="J8S10_002587"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HAZ9631151.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            5448..6809
                     /locus_tag="J8S10_002588"
     CDS             5448..6809
                     /locus_tag="J8S10_002588"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HAZ9631152.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            6769..7920
                     /locus_tag="J8S10_002589"
     CDS             6769..7920
                     /locus_tag="J8S10_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HAZ9631153.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            7895..9064
                     /locus_tag="J8S10_002590"
     CDS             7895..9064
                     /locus_tag="J8S10_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAZ9631154.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            9239..>9466
                     /locus_tag="J8S10_002591"
     CDS             9239..>9466
                     /locus_tag="J8S10_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAZ9631155.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVH"
BASE COUNT         3107 a         1652 c         2138 g         2569 t
ORIGIN      
        1 tttgtttaat attattccaa taaaattcaa atctttatca aatgaaattc caataaaaac
       61 ggaaaaaaag tgaaaagagg aatgaaaaaa tgacagaatt gataattggc ggagtcacag
      121 caagcacatt ggcagaaaag tataagacac ctctgtatgt gtatgatgaa gaaaagatga
      181 gacaaacgat gctgtcattc aagcgaggct ttgtatcgaa acgttttgat acaaaagtgc
      241 tttacgcctc taaagcattc caaacgattg agatgctgca tttagttcgt gaatatggat
      301 tcgggctaga tgttgtcagt ggtggggaaa tctataccgc tttgcaagct gattttccta
      361 gagatactat ctacttccat ggtaacaaca agacgccaga ggaactgatc tatgcacttg
      421 aaaatgattt gttgcatatt gttgccgata atttgatgga agttgaatta ttagcagaat
      481 taagccaacg ctatttaaaa aaaatctgta tcatgcttcg gttgaatgtc ggagtagaag
      541 cacatactca tgaatatatc gtcactgcgc atattgattc aaaattcggc atgagctatg
      601 aaagtaaaga gtgccaacaa gcccttcagt tgataaaaga aagcagctat ctagagttag
      661 aaggatttca tgctcatatc gggtcacaaa tttttgatgt tactgcttgg ttagctgaaa
      721 tcgacaaatt gacgaattac ttaaccgatt ttgaccaacc tctttccttg aatcttggcg
      781 gagggtttgg gattcgttat acacaaaatg atcagccgat cccagtcgaa gaggcactaa
      841 aaaaactgat tgaatatacg gaagaagctt tggaaaaacg aaaactgacc attcgtcaat
      901 tactgatcga accgggtaga agtattgttg gagaagctgg tacaacacta tacacgattg
      961 gtttcatcaa aaagacacca cataaaaaat attactttgt agatggcggg atgacagata
     1021 atatccgtcc agctctgtat caggcagaat acgattgtga tttagcagca aaactgtcgg
     1081 aagaaaaaac agagaaagtg acgattgcag gaaaaatgtg tgaatcaggc gatgtggtaa
     1141 ttaaagaagc ttatttgccg aaagcagaat cgggtgatct tttagctgtt tattccacgg
     1201 gagcttatgg atactcgatg agcagcaact acaatcgagc gacacgacca gcagttgttt
     1261 ttgtcaataa tggccaatca agactgattg ttcgcagaca agcattttct gatctactaa
     1321 ggggggaagt ttcctatgat ccttcataaa tataatggct gcggaaatga ttttatctta
     1381 ttagattacg cagaagacac agattatagt caattagccg cttctttatg cacaaaagaa
     1441 aaatatgata tagacggatt gatcgccgta aaaatcgatc cgttggaaat gatctattac
     1501 aacaaagatg gcagccgcgc gccgatgtgc ggaaatggca ttcgctgttt tgctcgatac
     1561 gtaaatgatc agaacatgat gaatgaacag gaattcaacg tagagacatt agcaggcaca
     1621 agaaaaatta cggtgttgga tccctcacct ttttattgca gcgtagatat gggagtgcca
     1681 gatgattctc cggaaaaaat caaagctaat caaacttatc caataaaaaa ccaggaaata
     1741 gagatcaatg gtgaaaaagt aacgatcact agtttatttt taggaacgat tcataccgtt
     1801 gtttttgttg aaaatgcgcg tgaggaagtc tggagaaaaa gaggtgaact gatctgtcat
     1861 catcctttgt tcaaagaaaa aaccaatgtc aactttgtag aagtagtcaa tgaacaagaa
     1921 ttgatcgtcc gtacctatga aagaggagta ggttggacac ttgcttgcgg tacaggttgc
     1981 tgtgcctctt atgtggttgc taaggaaact gggaaaattt cagcagatca ggtagttgtt
     2041 cacttggaac aaggagactt gatgatctct ggtgaggatg cgatacaaat ggctggccca
     2101 gcagttcatg aatggacaag aatattggag gaatgaagat gataaaaggt tcgatcgtgg
     2161 cgctgatcac gccgatgaat gaagagggat cagtagatta tgctggtttg gaaaaattga
     2221 tccaattcca tttagatgaa caaacagatg gattattagt tttaggtaca acaggagaat
     2281 cttctacgct cacacaatct gaggaggagc agatccttca actgacagta aagaaagtgg
     2341 ctggccgtgt gccggtgatt gcaggagctg gaacgaataa tacgaaagaa acgattgaaa
     2401 aagcgaagca ttttgcttct ttgggggcag acgcactttt ggtcatcacc ccttactaca
     2461 acaaaacaag tgatgcagga ctagctgctc attttacagc aattgcagaa gcctcaccga
     2521 ttccgcttat tttgtataat gttccttcta gaacaggcat gtcgattcca atccatgtat
     2581 tagtaaattt agcagaacat cctaatatca ttggtttgaa agaagcctca ggagatatgg
     2641 cttatgtgat ggatgccgct cggttgattg gagaagaatt cttcctttac agtggaaatg
     2701 atgatttgat cctaccagta atgagtgtag gaggaagcgg tgtaataagt gtatgggcga
     2761 atatccaacc taaaatagtc catgaattag taaaagatac gcaggacgga agatggcagc
     2821 aagcaaaaga aaagcaatta aatgcacttg aactgatcca tgccttgttc agtgagacca
     2881 atcctattcc tgtcaaagca gccatgtcat tattagactt accttccgga cctctacgcc
     2941 tgcctttagt ttctctttca aaagagaaaa agaaacaatt agctcagctt ttgttaaaag
     3001 aaaggacggt tgaaaaatga aaatcggact gattggcagt ggacagatgg gaaatagagt
     3061 cgaagaagtt gcacaagaaa gaggagatac ggtccttctt ttacggacgg cacctaaaga
     3121 agcaactacg cttgctttta cggaactgcc agaactgctt attgattttt ctcatccaga
     3181 taatttagag aaaatccttt cgtatagctt atcatatcaa cttccgttag tcattggcac
     3241 gacaggttat acacaatcac agttccaaga aataaaagaa catgccaaac atgtacctgt
     3301 gatgtatagt gctaattttt cgttcggcat catggtgatg aatcaactaa tcaagcaagc
     3361 agctgcaatg ttgcaaggct ggcagatcga actgattgaa aaacatcata gtcgtaaaaa
     3421 agatgcacca tctggtactg caaatatgct gcttcaaaca atccaagaag tgcaaaagct
     3481 gcagcccgta tacaactggc aagggaaaaa aagagaagaa aaccaaattg gtgtacacag
     3541 tattcgtgca ggttctttac ctggtgaaca tgatgtattg tttgctgcta ctgatgaaat
     3601 atttacgatc aaacatgaat ctttttctaa tcgaatcttt gctgcaggcg cagtagaagc
     3661 agcggactgg ttgaaagatc agtcaccagg ttattacaaa ttagaagatt tattaatgga
     3721 caaaggggtg taaaaaacgt ggaagctcaa gaaatcatcc gctacattca aacggcatct
     3781 aaaaagacgc ctgtgaaagt ctatctgaat gtaaccgagc caatcgaatt taaagaaagt
     3841 aaagtttttg gtgaaggaag cagcttcgtt gtttttggtg actatgagac gattgctccg
     3901 gttttagaag ctgaatcaga aaaaatcatt gaaatcgaaa tcgaaactgc tgcaagatac
     3961 agcgcagttc ctttgctaga tattaaaaaa attaatgctc gtatcgaacc aggtgctatt
     4021 atcagagatc aagtgtcaat cggcaacaat gccgtgatca tgatgggagc gattatcaat
     4081 attggtgcag taatcggtga aaacacgatg attgatatgg gtgctgtctt aggtggacga
     4141 gcgacagtgg gcaaaaactg ccatattggt gcaggagctg tcttagcagg tgtgatcgaa
     4201 ccagcatcgg ccaaaccggt tatcgtagaa gacggcgtac tggtaggtgc gaatgcagtg
     4261 attgttgaag gtgtccatat cggaaaagat gcagtcgtgg cagcaggagc agtggtttta
     4321 gaagatgtgg cagcagaaac tgttgtcggt ggaatacctg cacgtgtatt aaaaataagt
     4381 gatgatcaga caaaagaaaa tacagcattg attgctgcgt tacgcgaatt atagaggaga
     4441 tggagaaaaa tgcgcgaaat agatacctgt attgtggggg caaccggatt agtcggccaa
     4501 acgatgctca aagtgttaga agaatatgat tttccagtag gacgattgaa attattagct
     4561 tcaaaacgtt cagccggtaa agtttgtgta ttcaagaaaa agaaacacac tgtacaggaa
     4621 ttgacagaaa cttcatttga aggatatgat ttagcgctat tttctgcagg tgcttctgta
     4681 tccaaagagt ttgcgccaat cgcacgaagt cagggactat ttgtcataga taattcctca
     4741 gcatggcggg aagattcgga tattccatta atcgttccag aggtcaatct ggaagactat
     4801 acattgaatc ggctgattgc aaatccaaat tgttcaacca ttcaagcggt acttccgctt
     4861 aaagctttac aagaagcctt tggtatccag cgagtcaatt attcgaccta tcaagcagtt
     4921 tctggttccg ggcaaaaagg cattgaagat cttcatcgta cgcaaaatga cgaggaacca
     4981 gttttgtatc cttataatat tagccaaacg gtgattccgg aaatcgatca gcctttggaa
     5041 aatgggtata caaaagaaga acagaaaatg ataaatgaga cccgtaagat tctgcatcag
     5101 cctgctttgc cagtatcagc aacctgcgta cgtgtgccaa tcgaaaatgg acatggagtc
     5161 tctgtggcag ttcaactgca aaaagagttt acgacggaag aaattagaga gtgtctcagc
     5221 cagtttccag ggattcaatt agaagatgat ctagcagcac ataaatatcc gacgagcatt
     5281 cttgctagag gaacagatat ggtttatgtt gggaggatca gaaaagacac ttctttagag
     5341 aacggattgt tgttctatac gactgccgat aacatacgca aaggagccgc tgcgaatgcc
     5401 gtacagattg ctgcagcttt aatgcagaaa atagcggagg tggcaagatg agtaatacgc
     5461 tgaaagtagc gaaattcggc ggaacatcga tgtctcatga agagcaattc aaaaaagtcc
     5521 gtacaattgt tctttcagat cccaatcgcc aagtgatcgt tgtttctgct ttaggcaaac
     5581 gtacgtcaga tgatgacaaa gtaacagact tactttattt gatttatgct taccttcagc
     5641 atcatgttga ttggacaccc ctttggaaaa ggatttgtga tcgtttcatt caagtaagag
     5701 atgttcttgc cctgcagtta cctattgaag atgaactagc acgcatacag aaacaactgg
     5761 aagacgaaaa gataactgaa gattatttag taagtagagg tgaatatctg actgctcaac
     5821 tgatggctga gtatcttggt taccagttta ttgacgcaaa agacctgatt ttctttgact
     5881 atgatgggaa aatcgatcag gaaaaaacag cacaggaaat cacaaaagca tttaaaagat
     5941 atccgaaaat ggttgttcca gggttttacg gggcgaaccc tgcaggaaaa gaaaaattat
     6001 tgggccgtgg gggaagcgac attaccggcg cgatactggc gaagatgttg caagcggaaa
     6061 gttatgagaa ttggacggat gtttcaggaa tcatgatggc tgatccgcga atcatcgatc
     6121 atcctaaaat catcgaggaa atctctttta gagaactgag agagatggct tatatggggg
     6181 ctaacgttct tcatgaagca gctgttttcc cagttcaaga ggctgatatc cccatccaaa
     6241 taaaaaatac caatgatcct ttcgctcaag ggacaaaaat atcgaatcac gaaatagaaa
     6301 aggaaaatgg actgacagga atagctggac gcaaggattt tctttccatc actttattca
     6361 aacgtcatat gtccgatgaa atcgggttta tctggaaagc aatgagcatt tttgctaaac
     6421 atgagatatc aatcgaacat attccttcag ggatcgacaa tatcggagtg atcgtctcag
     6481 cagaagcgat tgccgataag ttatttctca tcacgaaaga attaaaagaa acacttggcg
     6541 tggaagaaat cgtcgtgatc gaagacttag ctttgatctc tgtcgttggg ggtccgcata
     6601 aagaattgat tggattatct gggaaagtgt tatcgatatt gaacaaatta gaaattcgca
     6661 catcgatctt atcacaagga gcacaggagt tgaatctgat catcggtgta ccgaataatc
     6721 aatatgaaac agtagtgaag ggtatctatg aagggatggt gaatacggat gctgaaagaa
     6781 tatcgaatgg cactccatca aattcctgaa atcgggtttc atgaattcaa gacaaaaaaa
     6841 tatttatatg aacaagtaaa aaacagcgag gccgttatcc atgaaatcgg cgaaacagga
     6901 ctactccttt attttgataa tcagcaagaa gaaacgattg cttttcgaac agatatcgat
     6961 gcactgccag tcaaagaaga aacgaatctc tcttttgctt ctaagcatga aggttatatg
     7021 catgcatgtg gtcatgacgg acatatggcg atgcttttag ggttgactga ctttataact
     7081 aaacacattg aggatcttat ttataatgta gtactgatct atcagccatc agaagaaatt
     7141 tccggtggcg cacaaagcgt tattcagtca ggattgttgg ataaatatga agtacaagca
     7201 atatttggct ttcatctatg gcctggacta gctaagggag aagttttctc tcgaccagga
     7261 cctttgatgg cacaaagcag tgaaacagac attatcatta aaggccagtc tgcacatatt
     7321 gcttctagtg aaaaaggaat cgatagtctg gaggcagctg tacgattttt gaagaatgtt
     7381 tatgattttg accggcaatt accggcagag tggaatcatc taatgaaatt tggccaaatc
     7441 caaggtggaa cgatccgaaa tgttttagct ggagaagtta ttgtatccgg aagtatccgt
     7501 tcttacagtt cagatatgca aaattatttg aagaggggat tagaccattt agcagaacag
     7561 tttcactcta cagctactat ttcttttcgc tataatgacg gctatccagc tgtaatcaac
     7621 catagaggct tatatgcagc actgttagat tcaaacaaac tacatgaatt agatgctcca
     7681 gttcttcaag ccgaagattt tggcatatat acgcaacaat atccatgtgt atttttcttt
     7741 ttaggtgtcg gtgatacccc tgctttacat gatccgacgt tcgattttga tatggatgtt
     7801 ttagaaaatg gtgtagaatg gtacaaaacg attcttttta cagaaaatct tcttgtaaaa
     7861 atcgatagca gttcaaaaga ggagcgagta aataatgatg aatttatcca atcgatttag
     7921 tcctaggctt tctagaatag aagtatcaaa aatacgacaa ttcgatcagc aaatatcgtc
     7981 gataccagat gtgatcaaac tcaccctggg agaaccggat tttccaactc ctgaacatgt
     8041 caagcaagca ggaatagcag cgattgaaga agacttttct cactataccg gaatgagagg
     8101 attagaggaa ctgcgggaag cggcttgtat atttcagcaa cagcgttatg gattaactta
     8161 tgatccgcaa acggaagttt tgacgacagt tggtgcaacg gaagcgattg cctctgcgtt
     8221 gttatctgtt ttggaagaag gagacaaggt tcttattcca gcgcctgctt attcaggata
     8281 tcagccatta gtggaactag ctggtgctga attgatcccg atagatactt ctgacacagg
     8341 gtttgtctgt cagccggaac aatttgaacg agcatttgaa caatatggat cagctgtcaa
     8401 agcagtcatt ttaaactatc ctaacaatcc tactgggacg acattgtctg caaaacaatt
     8461 gaaagcaatc gctgaggttt taaaaaaata tccggtattt gttataagtg atgaagtata
     8521 tgctgaattg acttatagtg gaacgcatat gtccatagct acttatcttc cagaacaaac
     8581 aatcgtgata agcgggttat ccaagtcaca tgcgatgact ggttggcgag tgggctttat
     8641 ttttgctcaa aaagccctta ttgacgaact aattaaagtc catcaatatc tggtgactgc
     8701 cgctacaacg atgtcgcaaa aagctgcggc tgaagcgcta ataaatgggg tgaaagatag
     8761 cgagaatatg aaagagcaat atcaaacacg aagagactat ctggtccagc aattggcgcc
     8821 tttaggattt gaagtgaccc agccaaacgg tgcattttac ttgttttgca aactcccagc
     8881 tgccattcaa actgactctt ggcagttttg tgtagaatta gcggaacagg caaaagttgc
     8941 gtgtatccca ggaattgcat ttggcccaga aggagaaggt tatatccgga tttcttatgc
     9001 tagcagcatg gaaaaattac atgaggcctg caaacggatc aaagactttt taacagaaca
     9061 gtgattcata gattttatca aaaaaacaat cgttaatttt gcggtatatt ctgcaaggag
     9121 acgattgttt tttaaattta gttcaaatga acgcgtttct tttgattcat aactaatgta
     9181 atgttaagtt taaattgttt agaatgattt taaaagaata ttcaaggagg tttcatcaat
     9241 ggaaaaaatc aaagttgtca ttgtaggtgc atctcatgga gggcatcaat cgatcttgga
     9301 actattgaca cgatacggtg aaaatgtaga tatcacgcta tttgaagcag gagactatat
     9361 ttccttcatg tcatgtggta tggagctgta tttagaagac aaggtaacag atgtaaatga
     9421 tgtacgtaat ttcagaccag aaaactttcc gcaatccaat gttcat
//
LOCUS       DADQDV010000091         9432 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.094, whole genome shotgun sequence.
ACCESSION   DADQDV010000091 DADQDV010000000
VERSION     DADQDV010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9432
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.094"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..680
                     /locus_tag="J8S10_002592"
     CDS             <1..680
                     /locus_tag="J8S10_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAZ9631156.1"
                     /translation="YFSRFSLATREAVQWIVIDMYAPYVSLVKKLFPNAQLIIDRFHI
                     VQHIGRTFLNHRVKETTARLKGTSHSQRGLGKKLKRYWKLLQKEEAKLNYEKRVWRAS
                     FKDYLTESEIVDRLLSACPNLRQGYQLYQDILYAVKKRDQSLFEDCLNREVSGLPETY
                     TTTLRTFKKFLPQIQNALHYSYSNGPLECLNNHIKVLKRNAYGFRSFYNFKLRIMIRH
                     GKTFLTK"
     gene            800..1000
                     /locus_tag="J8S10_002593"
     CDS             800..1000
                     /locus_tag="J8S10_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAZ9631157.1"
                     /translation="MIEEEQKNIWDRYYKADPSSKNTKIGESGLGLSIVKELVRLHHG
                     SIEVTSRKNEGTTFLIQFPKEK"
     gene            1076..1273
                     /locus_tag="J8S10_002594"
     CDS             1076..1273
                     /locus_tag="J8S10_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631158.1"
                     /translation="MVECLKNKKMEANFVKAVISGSIVFQEEYRDMEKDFSKKGIELI
                     DYPRSCPILDKEYPEILTTFF"
     gene            complement(1570..3117)
                     /locus_tag="J8S10_002595"
     CDS             complement(1570..3117)
                     /locus_tag="J8S10_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HAZ9631159.1"
                     /translation="MNITFLETSDMHGYVSPTDYSGRTDLALGTAKVSSKLKELRAKA
                     DGPVITIENGDFIQGSPLSYYLAKEYGSAKELTDLINQMSYDVQVLGNHEFNYGVDYL
                     EEAIKNYQAPILGANMVNKNDQPYFGNAYKIIEKVGVKIAILGLTTQYIPHWEKPETL
                     AGITFKSIVETAKEYVPLLRKQADLVIVSYHGGFEKDLLTGEDTEALTGENEGYELLQ
                     QVEGIDALFTGHQHRKIAETVHGVPVVQPGYRGEFIGEIRLTVEKKEGQVVVTDHQVA
                     LHSVEKSEPDPEILAAIVPVEEKLEKWLDQPLGKVNGNMRINDPMQARLEEHPYVEFI
                     NRVQLFASGSEISGTALFNNEGKGFGETITMRDVITNYIYPNTLAVIQINGADLRAAL
                     EQTANYLAVENNQIVFNPAFIQPKPQYYNYDMYEGIQYTIDMKQPVGQRITELRFKGH
                     PVLPQQMLEVVTNQYRAIGGGNYAMFGAEKIVREIQIDMTELIADYLNIHPRIEAKVN
                     HNFQVIL"
     gene            complement(3201..4004)
                     /locus_tag="J8S10_002596"
     CDS             complement(3201..4004)
                     /locus_tag="J8S10_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HAZ9631160.1"
                     /translation="MNILHISDIHFRREYEACEEGYKGMLATMQNPLIPLEQCIHHLL
                     QQTPLDLVIISGDLTEDGEIDDYRYLKTWLENALGETTILVTLGNHDIKEHFWVGWCD
                     EAASSAPYNQIVKYPEFTVISFDNSSYGYADGIVDDQQFQWLKKALEQEKDQPIFLVT
                     HHHLLSHQSSIPKWPGTERFLKLIAPYDIRCILNGHTHHTFTDEINGIPYFTVSSMSF
                     VGEDEGDGFVRFEERHGYNLYHLDQGRIVRQTTENFIPGNILKTLQMKD"
     gene            complement(4007..4789)
                     /gene="phnE"
                     /locus_tag="J8S10_002597"
     CDS             complement(4007..4789)
                     /gene="phnE"
                     /locus_tag="J8S10_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter, permease protein
                     PhnE"
                     /protein_id="HAZ9631161.1"
                     /translation="MMLREMNRRTLLSLVALVILVILSAATLDYSGLSTFSPSMGMDV
                     LRGLGQPDWQFLYDGSGEDLISLLLLTIGIACLGTMIATVLAIPITLISAVNLWQAHP
                     WVTKIGKLICNVLRAFPELVFAIIFVKVVGPGPFAGVMAIGVHQIGMLGKLFTEEMEA
                     MDERLVEEMHAVGANFWQTIFFVRIPYLMPIYCSLALNHFEIAVRSAATLGLVGAGGI
                     GAPLIFAIQTRSWSKVSIILIGVVVTVFILDQITGIIRKRLR"
     gene            complement(4786..5565)
                     /gene="phnE"
                     /locus_tag="J8S10_002598"
     CDS             complement(4786..5565)
                     /gene="phnE"
                     /locus_tag="J8S10_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter, permease protein
                     PhnE"
                     /protein_id="HAZ9631162.1"
                     /translation="MSLKETVHFKWYKHLLILLFLIVCFQGSAWITSADFSQVFQNSN
                     QMTVFLSRFIHPDFSYLPKLVEPMVKTLQMSLLGTVIGLILAIPVSFLATTVVTENRL
                     LSTIFRFLLGLVRTIPTLLLAALFVAVFGIGEATGVLTIAVFTFGMVSQLMFQAIETI
                     DFGPIEAAAAVGANKMQIAIWSIAPQVLSQFASYAFYAFEVNVRASTVLGYVGAGGIG
                     VILNSSLALLNYERVSIIILTILVTVAIVDKLSERVRRSLL"
     gene            complement(5537..6328)
                     /gene="phnC"
                     /locus_tag="J8S10_002599"
     CDS             complement(5537..6328)
                     /gene="phnC"
                     /locus_tag="J8S10_002599"
                     /EC_number="7.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter ATP-binding protein"
                     /protein_id="HAZ9631163.1"
                     /translation="MIIFDNVSKVYPNGVVGLKDIDLTIEDGEFVSIIGLSGAGKSTL
                     LRSINRLAETTKGDIRINGTSITKANKKELRQIRRQIGLISQSFNLVKRSTVQKNVLS
                     GRLGYYSTWKSILGLFTKEDYQQTKEALEKVGLSDKLQTRSDELSGGQQQRVSIARAL
                     VQQAPIILADEPVASLDPITTQKVMMDLKNINQTMDKTVIVNLHSVPLAREFSTRVLA
                     LKAAQVVFDGRPDDLTDERLEQIYGNAIFEEKAGEIDELERNRSL"
     gene            complement(6389..7318)
                     /locus_tag="J8S10_002600"
     CDS             complement(6389..7318)
                     /locus_tag="J8S10_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate/phosphite/phosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HAZ9631164.1"
                     /translation="MQFKQLAKGFIGVMLLTTLAACGSGNTSSSSEKESKEKLVVQFV
                     PTNNDGSMEAKAKPFAKYLSKKLDREVEVTLATDYSTIVEAMSSGQVDVGIMPPAAYV
                     QAKDAGAADAILTSQLGDYDQETGLPLKDKLTNTFKGEVLVRADSGLNKLTDLKGKNI
                     ATLSPNSASGYIYPVAELKDAGIDPTADTKMTTVNDIPSEITAVLNKQMDAAFVFEGA
                     RNVFASNFPDNDLFKDLKVLYLTKGDIPNDAIAVQPDMSKDLKAKIKETFLNMKDDKD
                     GKEAMALWGHQGYEEAADSAYDTIRDYTKKAAE"
     gene            7513..8196
                     /locus_tag="J8S10_002601"
     CDS             7513..8196
                     /locus_tag="J8S10_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="HAZ9631165.1"
                     /translation="MKKIHDTKQLTAYVEKHNLQDYMDSDILAMASLLFFEKEEHLIQ
                     TGKTSDYLYFLVDGTVMVYSYSSDTQNICIDYAKPATPLGEASSLWELSPKSSVKAVT
                     KCICISIPLNQYRTQLQKDVRFLQNICQLLSYRLNSGINLANSLTEPVETRLAKFILT
                     HHENERFSFRLTTCASILNVSYRHLLRTITNFREENIIEKKKNYYLIHDIEALEDLAE
                     NISSPVKAE"
     gene            8357..9400
                     /locus_tag="J8S10_002602"
     CDS             8357..9400
                     /locus_tag="J8S10_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HAZ9631166.1"
                     /translation="MKKILVSLLFLVSLVTLVGCSQSQGEKQSEKEKSKIALVLGFGG
                     VDDRSFNQAGWEGLEAWGKEKKLTAKKDFTYIETNNPEDNSTNIDQAIRNGFTTIISL
                     SYLQAEELENAAKDNPKLKFALVDGEITGKKNISSATFKDQESAYLAGLAAAYTTKSD
                     QVGFIGGMEGPVIQRFQSGFEAGVKAGATALNKEITVNVQYAASYDSLDKGKAIAASM
                     YKEGVDILYQAAGSTGAGVFQEAKARNENDYSRKVWVIGVDRDQADEGDYKMENGETG
                     NFTLTSTKKNVGAEVKEFAETSHNDKFPGGKHLTFGLKEEGVDLTKGQLSEEAYQAVS
                     DAKEKIISGDFRL"
BASE COUNT         2893 a         1933 c         1869 g         2737 t
ORIGIN      
        1 gctatttttc tcggttttca ttagcgactc gtgaagccgt tcaatggatt gttattgata
       61 tgtatgcgcc ttatgtttca ttggtgaaaa agcttttccc gaatgctcag ttgatcatcg
      121 accgtttcca catcgtccaa catattggca gaaccttctt gaatcatcga gtgaaagaaa
      181 ccacggcacg gcttaaagga acttcccact ctcaacgagg gttagggaaa aaattgaaac
      241 gctattggaa actcctacaa aaagaagaag caaagttaaa ctacgaaaaa agggtttggc
      301 gtgccagttt taaagattat ttgactgaaa gtgagattgt cgatcgactg ttatctgctt
      361 gtcccaacct gcgccaaggc tatcagttat accaagacat tctttatgcg gtaaagaaaa
      421 gagatcagtc attatttgag gactgtttaa acagagaagt cagcggtctt cctgaaacct
      481 atacaaccac tttacgaacg tttaaaaagt ttctgccaca gatccaaaat gcgcttcact
      541 acagctattc aaatggacca ttggaatgtt taaacaacca catcaaagta ttaaaacgca
      601 atgcgtacgg ctttcgcagc ttttacaatt tcaaactacg gatcatgatt cgtcatggca
      661 aaacattttt aaccaaataa acagaacaga aagagagttt cttctttctg ttctgtccaa
      721 attattctaa gatttctctt taccaacatc atttgacaaa gagcctgtat ttattactgt
      781 cgaggacaat ggcatcggca tgattgaaga ggaacaaaaa aacatttggg atcgctatta
      841 taaagccgat ccgtcaagta aaaatacaaa gataggcgag tcaggtcttg gattatcaat
      901 cgtgaaggaa ctagtgcgcc tgcaccacgg ttcaattgaa gtgaccagcc gaaaaaatga
      961 aggaacgacc ttcctgatac aatttccaaa agaaaaataa aattaccagt aaaaaaccgt
     1021 ggagagatag ctgctattga tttttgctat gtcttttctt tgagaggtat ccggtatggt
     1081 ggagtgtctg aaaaataaaa aaatggaggc caattttgtg aaagctgtta tttctggaag
     1141 tattgttttc caagaagaat atcgagatat ggaaaaagat ttcagtaaaa aaggcattga
     1201 attaattgat tatcctcgct catgtccgat cctagacaaa gagtatccag aaatcttgac
     1261 gacttttttt taaatatcgc agcagcggat ttattttttg tatttaatca agatcggaaa
     1321 ggggtattag gctatattgg tgccgcaact ttttcagaaa tgaagtattg tctgatgcaa
     1381 aatcttattc atggaaaaag gatcaaaata gtcttattta aggaaccatc agaggaaaat
     1441 tttttgtttt gatgaggtag atcgctggct aaagaatggc tggatggaaa tcagacagcc
     1501 taacaatttg gcataacaaa ggtgtgggca aaaaactgct cacacctttt tgaatttttt
     1561 atttatatac tacaaaatca cttgaaaatt atgattcact tttgcttcga tgcgtgggtg
     1621 aatattcaaa tagtcggcaa ttaattcggt catgtcgatt tggatttctc ggacaatttt
     1681 ctccgcacca aacatcgcat aatttcctcc gccgattgcc cgatattgat ttgtcaccac
     1741 ttccagcatt tgttgcggaa gaacggggtg acctttaaaa cgaagttcgg taatccgttg
     1801 tccaacaggc tgtttcatat caatagtgta ctgaatccct tcatacatgt cataattgta
     1861 gtactggggc ttaggctgaa taaaggctgg attgaatacg atttggttat tttctacagc
     1921 taaataattt gcggtctgct ccaacgccgc tctcaaatct gcaccattta tttgaatcac
     1981 tgccagagta ttcggataaa tatagttggt gatgacgtcc cgcatcgtga tcgtctcacc
     2041 aaagcctttt ccttcattat tgaataacgc agttccagaa atctctgagc cgctggcaaa
     2101 taattgtaca cgattaataa actctacata gggatgttcc tcaagacgag cctgcatcgg
     2161 atcattaata cgcatatttc cgttcacttt acctaagggt tgatccaacc atttctctag
     2221 tttttcttct accggtacga tcgctgcaag aatttctgga tcaggctctg atttttcaac
     2281 tgagtgtaaa gcaacctggt gatctgtaac aaccacttgc ccctcttttt tctcgacggt
     2341 aagacgaatt tcaccgatga actcgccacg atagcctggt tgaacaacgg gaactccatg
     2401 aaccgtttca gcaattttcc ggtgctgatg accggtgaaa agggcgtcaa tgccttcaac
     2461 ctgctgcaat agctcgtagc cttcattctc tccagttagc gcttctgtgt cctcaccggt
     2521 taacaagtct ttttcaaatc cgccgtggta actaacgatt accaagtctg cttgtttcct
     2581 taatagagga acatattctt ttgctgtttc gacgatactc ttaaacgtaa ttcctgctaa
     2641 ggtttctggc ttttcccagt gaggaatgta ttgtgtcgtt aatcccaaga tagcaatttt
     2701 tacacccacc ttttcgataa tcttataggc gtttccaaag tatggttggt catttttgtt
     2761 caccatattg gctcctaata taggcgcttg ataattctta atcgcttcct cgagataatc
     2821 cacaccatag ttaaactcat gatttcccaa cacttgaaca tcatagctca tttggttaat
     2881 caagtctgta agctctttgg ctgaaccata ttctttagca agataataac tcaaaggaga
     2941 cccttggatg aaatcaccat tttcgatcgt aattaccggt ccatctgctt ttgcccgtaa
     3001 ttccttcagt ttcgacgata ctttagccgt tcctaaggcc agatcggttc tgccggaata
     3061 gtctgttggt gaaacatagc catgcatatc acttgtctct aaaaacgtaa tgttcattct
     3121 gcgtgctcct ttagctgact caaaatagaa aaaccgaagc gtattcagct gttcggtctc
     3181 tttttttgat ttataatgcc ttaatccttc atttgaagtg tttttaaaat gttgcctgga
     3241 ataaagtttt ctgttgtctg gcgaacaatc cttccttgat cgagatgata aaggttatac
     3301 ccatgacgtt cttcaaagcg tacgaagcca tcgccttcat cttcaccaac aaaggacata
     3361 ctcgatacag taaaataggg gatcccatta atttcatcag taaatgtgtg atgggtatga
     3421 ccgtttagga tacagcgaat atcgtaaggt gcgattagct tcaagaaacg ttcggtacca
     3481 ggccattttg gtatactgct ttggtgagac agtagatgat gatgggtgac caagaaaatc
     3541 ggttggtctt tttcttgctc taaggctttt ttcagccatt gaaattgctg atcgtccact
     3601 ataccatctg cgtatccata gcttgaatta tcaaaggaaa tcactgtaaa ctcaggatat
     3661 ttgactatct ggttgtacgg ggcagaagag gcggcttcat cgcaccagcc tacccaaaaa
     3721 tgttctttga tatcgtgatt gcctagagta acaagaatcg tcgtttctcc tagcgcattt
     3781 tccagccaag tcttcaagta tcgataatcg tctatttcgc catcttcggt taaatctccg
     3841 ctgataatca caaggtccaa gggtgtttgc tgcaggagat gatgaatgca ttgctccaga
     3901 gggataaggg gattctgcat cgtagccagc attcccttat agccttcttc acaagcctca
     3961 tactctctgc gaaagtgtat atctgatata tgcaatatat tcattcttat ctcaatctct
     4021 ttcttataat tccggttatt tgatctaaaa taaacacggt tacgactacg ccaatcaaaa
     4081 taatactcac tttgctccaa gaccgagttt gaatcgcgaa tatcaatgga gcaccgattc
     4141 cgccagcgcc aactaagcct aaggtagccg cactacgaac cgctatttca aaatgattta
     4201 atgctaaaga acaataaatc ggcatcaaat aggggatgcg aacaaagaaa atcgtttgcc
     4261 aaaaatttgc tcctaccgca tgcatttctt caacaagtcg ctcatccatc gcttccattt
     4321 cttctgtaaa aagtttgcca agcattccga tctgatggac gccaatcgcc ataacaccag
     4381 caaaggggcc aggtccgacg actttcacaa aaataattgc aaaaactagt tcaggaaaag
     4441 ctcgtaaaac attacagata agcttgccaa tttttgttac ccatggatgt gcttgccaga
     4501 ggttaaccgc actgatcaag gtaatgggaa tcgctaatac cgtagcgatc attgtcccta
     4561 aacaggcgat tccaatggtt aataatagca aactaatcaa atcctcgccg ctgccatcat
     4621 atagaaactg ccaatcaggc tgacctaacc ctctcaaaac gtccattccc atggaaggag
     4681 agaaggtgct taatccagag taatccagag tagcggccga caaaataacg agaatcacta
     4741 aagcaactaa tgataaaagg gttcttctgt tcatttcacg aagcatcata acagggacct
     4801 cctgacacgt tcacttaatt tatcaacgat cgcgacagtt actaggatcg ttagaataat
     4861 gattgaaact cgttcataat tcaaaagcgc aagtgaggaa tttagaataa cgccaatacc
     4921 accagctccg acatatccaa ggacagtaga agcacgaaca ttcacctcaa acgcgtaaaa
     4981 agcatagctc gcaaactgac tcaaaacttg tggagcgatc gaccaaatag cgatttgcat
     5041 tttatttgct ccaacagccg cagcggcttc aatcgggcca aagtcaatgg tttcaattgc
     5101 ttgaaacatt aattgtgaca ccataccaaa agtaaagaca gcgatagtca acacgccagt
     5161 cgcttcacca attccaaaca cagcaacaaa aagcgcggct aaaagcaggg tagggatggt
     5221 ccgtactaaa cctaaaagaa aacgaaagat ggtagaaaga agacggtttt ctgtcactac
     5281 agtggtcgct aaaaaactaa cagggatcgc taaaattaag ccaatgaccg ttccaagcaa
     5341 agacatttga agtgttttca ccataggctc gactaattta ggtaaatagc taaagtctgg
     5401 atgaatgaag cgtgataaaa agacagtcat ttgattggag ttttgaaaaa cctgagaaaa
     5461 atcagctgac gtgatccagg cacttccttg aaaacaaaca attaagaaca gaagaataag
     5521 caggtgttta taccatttaa agtgaacggt ttctttcaag ctcatcgatt tcgcctgcct
     5581 tttcttcaaa gattgcattg ccataaattt gctctaagcg ttcatcggtt aagtcgtctg
     5641 gacgaccatc aaagacaacc tgagcagctt ttaacgcgag cacacgcgta gaaaactcac
     5701 gagccagagg gactgaatgc agattgacaa tgactgtttt atccatcgtt tgattgatat
     5761 tttttaggtc catcataacc ttttgagtcg tgattggatc taatgatgca acgggttcat
     5821 ccgctaaaat aatgggggct tgctgcacga gtgctcgcgc aatggatact cgctgttgtt
     5881 gcccaccact gagctcatca ctgcgtgtct gcaatttatc agacaaacca actttttcca
     5941 gtgcttcctt tgtctgctgg tagtcttcct tcgtaaaaag acctaaaata cttttccaag
     6001 tggagtaata gcccaaacgt ccagatagca catttttctg aaccgtacta cgctttacca
     6061 gattgaagct ttgcgagatt agaccaatct ggcggcgaat ctgtcgcagc tcttttttat
     6121 tcgcttttgt aatagaggtt ccattaatgc gaatatctcc tttggtggtt tctgccaagc
     6181 gattgatact gcgcagcaga gtgctctttc cagcaccact caaccctatg atggaaacaa
     6241 attctccatc ttcaattgtt aagtcaatat ccttcaagcc aacaacgcca ttgggataga
     6301 ccttcgaaac attgtcaaaa ataatcatta tccttctcca tttttttaag tgtaagcaaa
     6361 aaaaagcttg ctgacactta ctgatgtttt attctgctgc ttttttcgtg tagtctctga
     6421 tcgtgtcata ggcagaatca gcagcttctt catagccctg atgcccccac aaagccattg
     6481 cttctttgcc atctttatca tccttcatat ttaagaaggt ctctttaatt ttcgctttta
     6541 aatcttttga catgtcaggc tgtacagcga ttgcgtcatt cggaatatcg ccttttgtca
     6601 ggtacaggac ttttaaatcc ttaaataaat cattatctgg gaaattcgaa gcaaaaacat
     6661 ttcgcgcgcc ttcaaaaaca aacgccgcat ccatttgctt gttcaacact gcggtaatct
     6721 cactcggaat atcattcaca gtggtcatct ttgtatctgc agtaggatca atcccagcat
     6781 ctttcaattc agcgacagga tagatgtagc cgctagcaga gttaggactt aaggttgcga
     6841 tattttttcc ttttaaatca gttaacttat tcaatccgct atcggcacga accaatactt
     6901 ctcctttaaa ggtgttcgta agtttgtcct ttaatggcaa gccagtttct tgatcataat
     6961 cgccgagctg agaagtcagg attgcatctg cagctccagc atcctttgct tgaacatagg
     7021 ctgcaggcgg cataattccg acatcgactt gaccagaaga catcgcttcg acgatcgttg
     7081 aataatcagt agctaacgtc acttctacct cacgatctaa ctttttcgat aaatacttag
     7141 caaatggttt tgcttttgcc tccatactac catcattgtt tgttggaacg aattgaacaa
     7201 ctaatttttc tttgctctct ttttctgagc tgctacttgt attcccagaa ccgcaggccg
     7261 ccaaagtggt caataacatg actccgatga acccttttgc taactgtttg aactgcattt
     7321 ttctcctcct gttggatata atttctaata cgtctaaatc atagcaggga atcaaaatca
     7381 atgaagtgac gcacgtccta ttttacacaa cttttacata caatttacaa acaattataa
     7441 ataattattc gtattgagcc gaaaaacaat ctaagctata ataaagaaaa acttcttaga
     7501 ggtgacgatt tcatgaaaaa aatccatgat acgaagcaat taactgctta cgttgagaag
     7561 cacaacctgc aggattatat ggattcagat atattggcaa tggcttcttt actttttttt
     7621 gaaaaggaag agcacctcat tcaaacggga aaaacctcag attatttgta ttttttagtg
     7681 gatgggacgg taatggtgta ctcgtattct tctgatacac aaaatatttg catcgattac
     7741 gcaaagcccg ctacaccact cggcgaagcc tcttcattgt gggaattatc gccgaaaagc
     7801 agcgttaaag cagtgactaa gtgcatctgt atcagcattc cgctaaatca atatcgaaca
     7861 cagcttcaaa aagatgttcg ctttttgcag aatatttgcc agttactaag ttatcgttta
     7921 aattccggga taaatttggc gaactcactg acagaacctg ttgaaactcg tttagcaaag
     7981 tttattttga cccatcacga aaacgaacgt ttctcatttc ggttaaccac ctgcgcctca
     8041 atcttaaatg tcagttatcg acatctttta cgaacaatca cgaattttcg tgaggagaat
     8101 attatcgaaa agaaaaagaa ttattacttg attcatgata tcgaagcttt agaggactta
     8161 gctgagaata taagtagtcc agtaaaagca gaataacagc tataaaaaaa cagcagtcag
     8221 aagtgattgc tggttttttg atagtggaga aattgggaaa cggaaaatct tcgttgaaga
     8281 gtagtgttct atatattggt atgctatact tttaaaagtt caatgtgtca agacacataa
     8341 aaaggggaga aaaattttga agaaaatact tgtttcattg ttgtttttgg tgtcattagt
     8401 aacgttagtc ggctgtagtc agtctcaggg ggagaagcaa agtgaaaaag agaaaagtaa
     8461 aatcgctttg gttcttggat ttggcggggt tgatgaccgc tccttcaatc aagctggctg
     8521 ggaaggatta gaggcttggg gaaaagagaa aaagctgaca gcaaaaaaag attttacgta
     8581 tatagaaacg aacaatccag aggataacag taccaatatc gatcaggcaa tcagaaacgg
     8641 ctttaccacc attattagct tgagctactt gcaagcagag gaactggaaa atgctgctaa
     8701 agataatcca aagttgaaat ttgccttggt agatggtgag attactggga aaaagaatat
     8761 ctcatcagca acctttaaag atcaagaaag tgcgtattta gcaggactag ctgccgcata
     8821 tacgacaaaa agtgatcaag taggctttat tggtggaatg gaagggcccg tgatccaacg
     8881 tttccaaagc ggatttgaag ctggcgttaa ggcaggggcc acagcactga acaaggaaat
     8941 tactgttaac gtacaatatg ctgcatccta tgattcgcta gataaaggaa aagctattgc
     9001 tgcttctatg tacaaagagg gagtcgatat tctttatcag gcggcaggaa gtactggagc
     9061 tggggtgttc caagaagcaa aagcccgcaa tgaaaacgac tatagcagaa aagtatgggt
     9121 gattggtgta gatcgcgatc aagcggatga aggggattat aaaatggaga acggcgagac
     9181 agggaatttc acgttgactt ctacaaagaa aaatgtcggt gcagaagtca aagaatttgc
     9241 agaaacttct cataacgata aatttcctgg cggcaagcat ttgacctttg gtttgaaaga
     9301 agaaggggta gatctgacaa aaggacaatt atcagaggaa gcctatcagg cagtttcaga
     9361 cgcaaaagag aaaatcatca gtggtgattt cagactgtag acaaagtcca ttttatggat
     9421 gatgtctaca gt
//
LOCUS       DADQDV010000092         9417 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.095, whole genome shotgun sequence.
ACCESSION   DADQDV010000092 DADQDV010000000
VERSION     DADQDV010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9417
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.095"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..368)
                     /locus_tag="J8S10_002603"
     CDS             complement(<1..368)
                     /locus_tag="J8S10_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002606082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAZ9631167.1"
                     /translation="MINFSIKELNAFAVIGQEVELTNYQKKNIQISTQFWRKFNSSLK
                     KAYLSQSGNWVKYAFMERRNGKLYYFCSIPQRTITPEGFLYKEIPSYKYLVVEHIGAM
                     DKIYETYGKIYEEIIPSTSY"
     gene            complement(365..607)
                     /locus_tag="J8S10_002604"
     CDS             complement(365..607)
                     /locus_tag="J8S10_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HAZ9631168.1"
                     /translation="MENELLENLGRLHTTELGVIRIKKNLSLNVENVIEWCKEKISLS
                     NAEITRKGKNWYITIDNCIITVNAYSYTVITAHKVK"
     gene            complement(1153..1683)
                     /locus_tag="J8S10_002605"
     CDS             complement(1153..1683)
                     /locus_tag="J8S10_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAZ9631169.1"
                     /translation="MRKVVLFIAMSLDGYIADGNGGVAWLNGHGNDNENIDTYTEFTK
                     DIDTVLMGWNTSHQVVTELSPQEWVYNKFTTYVLTHKECNSSQQIHFTSENPVLLLER
                     LKQEAGKDIWICGGANLVQQLVSKNMIDKYYISVIPTLLGNGVRLLGNIDREIKLRLC
                     KTQTYNGITDLIYMRR"
     gene            complement(1865..2521)
                     /locus_tag="J8S10_002606"
     CDS             complement(1865..2521)
                     /locus_tag="J8S10_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005603505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HAZ9631170.1"
                     /translation="MNKEWSELNKTMQAQIKKKDTYKRGIDTLLTLRSQLIQTLVSFK
                     EELCREDFNSIPFINADGYHSKTIAYSIWHIFRIEDIVVHTVINEDEQVFFAGNYQER
                     INSPIITTGNELMKQQIADFSKQLNLEELYLYIFEVWESTEKMLERLSYDELKRKIPK
                     ERKGYLESLNVVNDNEKAIWLIDYWCNKDICGLIQMPFSRHWIMHTEACLRIKNKIHS
                     "
     gene            complement(2648..3121)
                     /gene="dfrF"
                     /locus_tag="J8S10_002607"
     CDS             complement(2648..3121)
                     /gene="dfrF"
                     /locus_tag="J8S10_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrF"
                     /protein_id="HAZ9631171.1"
                     /translation="MIGLIVARSKNNVIGKNGNIPWKIKGEQKQFRELTTGNVVIMGR
                     KSYEEIGHPLPNRMNIVVSTTTEYQGDNLVSVKSLEDALLLAKGRDVYISGGYGLFKE
                     ALQIVDKMYITEVDLNIEDGDTFFPEFDINDFEVLIGETLGEEVKYTRTFYVRKK"
     gene            complement(3540..3758)
                     /locus_tag="J8S10_002608"
                     /pseudo
     CDS             complement(3540..3758)
                     /locus_tag="J8S10_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173391.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(3789..5003)
                     /locus_tag="J8S10_002609"
     CDS             complement(3789..5003)
                     /locus_tag="J8S10_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HAZ9631172.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            complement(5344..5586)
                     /locus_tag="J8S10_002610"
     CDS             complement(5344..5586)
                     /locus_tag="J8S10_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAZ9631173.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            complement(5618..6175)
                     /locus_tag="J8S10_002611"
     CDS             complement(5618..6175)
                     /locus_tag="J8S10_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAZ9631174.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            complement(6188..6376)
                     /locus_tag="J8S10_002612"
     CDS             complement(6188..6376)
                     /locus_tag="J8S10_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HAZ9631175.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            complement(6389..6955)
                     /gene="amaP"
                     /locus_tag="J8S10_002613"
     CDS             complement(6389..6955)
                     /gene="amaP"
                     /locus_tag="J8S10_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HAZ9631176.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
     gene            8185..8658
                     /locus_tag="J8S10_002614"
     CDS             8185..8658
                     /locus_tag="J8S10_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HAZ9631177.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            8667..8894
                     /locus_tag="J8S10_002615"
     CDS             8667..8894
                     /locus_tag="J8S10_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAZ9631178.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
BASE COUNT         2879 a         1847 c         1368 g         3323 t
ORIGIN      
        1 atatacgatg tactaggaat aatttcttca taaatcttgc cataagtttc atatatttta
       61 tccatagcac caatatgctc cacaaccaaa tatttataag acggtatttc tttatacaga
      121 aagccctctg gggtaatggt tctttgggga atagaacaga aataataaag ttttccattt
      181 cttctttcca taaaagcata ttttacccaa tttcctgatt gtgaaagata cgcttttttc
      241 aaactactgt taaactttct ccaaaactgt gtactaatct gaatattctt tttttgataa
      301 ttagtcagtt ctacttcctg cccaataact gcaaatgcgt ttaattcctt tatagaaaaa
      361 tttatcattt taccttgtga gcagtgataa cggtataact gtacgcattt accgttataa
      421 tacaattatc aatcgttata taccagtttt ttccttttct tgtgatttcc gcattagaaa
      481 ggctaatttt ttctttgcac cattcaatta cattttctac attcaaagat aagttctttt
      541 taattctaat aacgccaagt tcagttgtgt gaagtcttcc taagttttcc agtaattcat
      601 tttccatatt ttgatacctc atttttcagc aaatttattt gtatgtttta taccccaatt
      661 ataacattct catatcagca ctacaataaa aataattaag caccaataat cttattgaac
      721 atctccaacc gtaaatcttt cacaccatca gtgataaaca ctgagctgac agcaattacg
      781 acaactacca taattgcctg cacttaaatt tctgcaaaag aaaacgacaa tcaatttctt
      841 attttttgaa atcaactgtc tttctcatat ttactattca attttcatag tgatataggt
      901 acaatttata tcactactgt aaaaatgggg ttttgcctta taaatacagc gttttccgct
      961 tgttagtgta tagtgtttct tgttttttgt gccccccttg ttagataacg ggggctttga
     1021 acggctcgca agctcgccga accgccgaag cgaaccgccc ccttgcaagc atggcggaaa
     1081 aatcttaagg attttcccgc caacgtggtc ggatcgctcc gtcggtttaa cagcttttct
     1141 gtttctctct agttatctac gcatataaat caaatcggtt attccgttat aagtctgtgt
     1201 tttacaaagc cttaacttta tttccctgtc tatgttgccc aaaagacgaa ccccatttcc
     1261 taacagagta ggaataacag aaatgtaata tttatcaatc atatttttgc ttaccaactg
     1321 ctgaacaaga tttgctccgc cacaaatcca aatatccttt cctgcttctt gttttagccg
     1381 ttccaataat aaaacaggat tttcacttgt aaaatgaatt tgttgggaag aattgcactc
     1441 tttatgtgtt aatacataag ttgtaaattt attatatacc cattcttgcg gagaaagttc
     1501 agtaacaacc tgatgagaag tattccaccc cattaagaca gtatctatat ctttggtaaa
     1561 ttctgtataa gtgtcgatgt tttcattgtc atttccatga ccatttagcc aagctactcc
     1621 accattaccg tccgcaatat atccgtcaag gctcatggca ataaataaaa ctacttttct
     1681 cattttttct cttttataaa tacaaacagg aatttatttc tcttttttac tcataaggga
     1741 acaactgatt gctacaaata aacccattaa aatccatgga aatgctgctc ttataaaatc
     1801 actaaccata ctttattcct ccttaaattc caatttcctt agttctacaa actgaaattt
     1861 ttgcctatga atgtatcttg ttctttatac gcaaacaggc ttctgtgtgc ataatccaat
     1921 gtcttgaaaa cggcatttga attagtccac aaatatcttt attacaccaa taatcaatca
     1981 gccaaattgc tttttcattg tcgtttacta cattcaacga ttctaagtat ccttttcttt
     2041 ctttcggtat ttttcttttc aattcatcat aagataaccg ttcaagcatt ttctcagtgc
     2101 tttcccatac ttcgaaaata tataaatata attcttccag attaagctgt tttgaaaagt
     2161 ctgcaatctg ctgtttcatg agttcatttc ctgttgtaat gataggtgaa ttgatacgct
     2221 cttgataatt gcctgcaaaa aatacttgtt catcttcatt tatcactgta tgcacaacta
     2281 tatcttcaat gcggaaaata tgccaaatag aataagcaat cgtcttacta tgataaccat
     2341 cagcgtttat gaaggggatt gagttaaaat cttctctgca taattcttct ttgaaagata
     2401 ctaaggtttg tattaactga cttcgtaaag taagtaaagt atcaataccc ctcttataag
     2461 tatctttctt ttttatttgt gcctgcattg ttttattaag ttcagaccat tccttattca
     2521 tattcaatcc tctctcaaat tctgatttta tcgccccata caaactggaa tttgtcttac
     2581 aacaatttat atatgcataa aaagcaatat atttatgaaa acaccctaaa tccaaaattt
     2641 actcaattca ttttttcctt acataaaatg ttctcgtata tttcacttcc tcaccaagtg
     2701 tttcccctat caaaacttca aaatcattga tatcaaattc tggaaagaat gtatctccat
     2761 cttcaatatt taaatctact tctgtgatat acattttatc tactatttgc aaagcttcct
     2821 taaatagtcc atatccacca gatatgtata catctcgtcc tttagccaat aataatgcat
     2881 cttctaatga tttaactgaa actaaattat ctccttgata ctctgttgtg gtggaaacaa
     2941 caatattcat tctattaggc aacggatgac cgatttcttc ataagacttt cgccccataa
     3001 taaccacatt acccgttgtt aactctctaa attgcttttg ttctcccttt attttccatg
     3061 gtatattacc attcttgcct ataacattat tctttgacct cgcaacaatc aaacctatca
     3121 tctatttcat cctccataat atgatgtcgt acctgtgatt ccatcaagtg caccacatct
     3181 taacaaactc aaaattatct cgaactaacc agctcgacaa attccttttt tgtcttcatc
     3241 tgcattatat catattgtta taagcattgc catttctttt ctgcttttga aaagttactt
     3301 atcagcctat gttttgtaaa gggtgatatt cagcatttct cacgcaacaa gcccttgaca
     3361 aaccatagac taataagttt taaggtaatc aagcagaaat gaaatagtct gctgtttcac
     3421 ggcaacaaaa aagagatacc aacacactta tgtagtatct cttagtctag tagcaatatt
     3481 cttttgtttg caagcaggta aacatgggct gtttcttaat atctttttgt ttgggaaaca
     3541 cctttttccc atcctttcac cgttgccatc tctgctgcgc acaatgccac agggataaac
     3601 catagcaaac cgcctaataa caagaaaaat actaagctga agcctgaggt cgcgaatgtg
     3661 ggatattcat ataatgaaac gaccattgag atggtcatag ccaaaaagcc aaagaacgtt
     3721 aatttttttg caggaatttt cgttttgctt tgttgcatga atcttcctct tttctatttg
     3781 aatttgtttc aattgagttt gttgccaaag aagaaaaagt ccaatccttc ttcttgttct
     3841 tcttttgtag tagtgatcgt tgtaaagtgc atcgccgatt ttaaaatcac tgttgtcagc
     3901 acataggcat acacggcagt aatgatgaca ccaatcactt gaatccctaa gaagtaccag
     3961 ctgcttggat tcgttagtaa atggctgtta gatgcaaaga tccctatcag aatcgtacct
     4021 gtgaatccgc ccatgccatg aacaccccac acatcaagtg catcatccca ttgtttcttt
     4081 ttacgaaaat caacagcagc atgacagacg atacccgcaa tgatcccaat cagcatggca
     4141 ctttttgctt ctacataacc ggcacaaggc gtaatggctg ccaatccagc aacggatcct
     4201 gttagtacgt cgacaaaatc aaagccattt ccttttactt ttgcaatgat cagccaagta
     4261 atcatcgcaa atgcaagagc gatgaatgtt gaaccaaatg cattgactgc ttgttcatct
     4321 gctcgaagtg caccaccgga attaaaaccg aaccagccaa accaaagcag tcctgtaccg
     4381 atagcagctg ccataagact gctatgctga cttctttctc ctaaaggaat ctttctttga
     4441 ccaagtgtga ggatacatgc taaagagccg aatccagctg tcgtgtggat gactgctcca
     4501 ccagcgaaat ctctaaatcc catctgatcc aaaaatccgc caccccatat ccagtggcaa
     4561 acagggaaat aaatcagcag attccaaaaa ataacaagta taatatagcc ttttaaattc
     4621 aatctccctg caaaagctcc tgtcatcaaa ggaacggtaa tcacgataaa catcagttgg
     4681 taaagaaaga acattaaaaa tggaatcgtt gcaccatgaa acatgttggg gaagcttgta
     4741 acatgtctca tcaaaaagaa atctgccggg tttccaataa caccgccgat atcccgtcca
     4801 aaggccaatc cgaatccacc aaatacccac ataatcgttg ttatcccaac ggagagaaaa
     4861 gattgagaca tgatcgttag tatattattc ttccgtgcta atccgccgta aaaaaaagct
     4921 agaccaggag tcatcaggca aaccattgct gtacataaaa tcatgaatgc tgtatctcct
     4981 gtattgatag gtaatgtatt catttttttc gcctcctttc tacgattacg agtataaaag
     5041 aaggtgtagt tgtttttttc ttctgttttt ttgaattaat acttgcattt ataaaagaca
     5101 gacaattaat aaaagcttga tgtgttgtgc tctttttcgt ttttcacaca aataaagaca
     5161 aaaaataaac ggtcttcttt ttatagaaaa ccgtttattt tcgtcttttt ttatttttaa
     5221 agatattttt tcataaggaa taaagaatac ttcatataaa atatataaaa aagaaccgca
     5281 gcgagtgtcg ctacggttct caaatttgtt cttcatttca acataagttt ttcttcaatt
     5341 tgcttataat ttacgtgcaa agaatgaaac gactaatact aaaatgattg caccgatcaa
     5401 tgatggaatg atagccattc ctgcaattgt tggtccccaa gttcctagta aagcttgtcc
     5461 aattgctgaa cctactaaac cagcaatgat gtttgcgatg atccccattg atgatccttt
     5521 attcgtgatt gctcctgcaa ttgctccaat gataccgccg acgattaatg cccaaataaa
     5581 tcccatttta aattcctcct aactgacttc ttacttctta ttgtacacgt ggttcgttat
     5641 tttctttgac tttttgtgca cctttgccta cagcagattt tgctttatct gtttggcgtg
     5701 aagcaaattg tcctgtggat tttgctgctt ctgttacttt gtcttgtact gtttcttgat
     5761 ctttttggta ttcttcttgt gttttgatgt ctgcaacatt cacattcact tcgataacat
     5821 ctaaatgtgt catattgttt acttcagtac tgatcaattc tttgatttgg ttgtaaatat
     5881 cttcgatgtc tttaccgtat tctacgatca catctagatc cacagctact tgtttcttac
     5941 ctacttctgt attgatacct gctgttacgt tatctgtgtt gactaatttt tcagccatat
     6001 ttgagaaaaa tccgccatct aatgtcaata gaccatctac atctttcaat gcataaccga
     6061 tgattttttg gatgactttg tcttcataag tcaattcacc attcatcatg cggttttctc
     6121 ctttttcatt tgccaaaact gatccatttg ttgtattcat gtttttgttt tccatctttg
     6181 tttcctccta tgatttaaaa aattgatcaa ctattcctga ctgtttcaaa taaaaaccga
     6241 ttcctgcgcc aattgctgtc atgattatga tcaacaatgt cttgaaaaat ccaatcgtta
     6301 accataaaac agctagcagt agtccaagac ccccaaagat aatagggagc ttgtatgctg
     6361 aaaatagttc tttcattatt tggccctcct attccactcg agagtgcttg tagtctcttg
     6421 tatcttcttg ttcttcataa ccgctgtatg tgactgccac tttgaccgtt tcttttgttc
     6481 cgagtacttt agttacttct tcttcgatat cttgcatcaa tacacctgtt ttccctacta
     6541 atgaagaagt tcgtttcaag tctccgttga catggatatg gattcgattt ttcgttgaac
     6601 gtatccgtac tttaggtgaa tgaatgaact cttcttcgtg taaatgggaa cgtaccaacc
     6661 cttcgatcgc ttttttgtcg attgttagtt tgccatcttc ccgtttcata acgaaagttc
     6721 ctcttgactt tggatagaaa agaacgacta gcaagatgat aatagcaaga acggcaaata
     6781 ctacagctgc ccagaaaata tattgttgca tgtagtaatt cgttaaagta aagaagcgaa
     6841 atcgttccaa ttgttcaggc ataatatacg gcgcattgat caacgcaatc gctagaaata
     6901 ctgaaagtag cagtaaactc atgataacac cgattatttt taacccctta ttcattttcc
     6961 acctcctata aacttatttt taccctgtaa ataactctac cgacaatcac agtatagata
     7021 gcgaacagtt agcatagcat cagtaaataa agcgctacca aacattgctg gatcataacg
     7081 gcgttttatt gccagtctga tactgaaata acaattgctt acttattctc tatttacttt
     7141 tgattgctgg ctatacttaa aggatattat tcaagattaa aaattgcaaa gattatgctc
     7201 agttattatt acaagattct atttatttat taaatttttt cggagaatta aaaaatacaa
     7261 taaataactt tagttacttt aatgcgttct tactttattt ttatattatc atttttctta
     7321 ttcacttctt tggtttatac tattcttata aataaaaacg aggtatgtcc tatgatgaaa
     7381 agattgtact attcattgat cataacgatt ggctatttga ttgtatcaaa tctaggaaat
     7441 atggtatttg gtatcagtaa agaattcagt tggactacta cattatggga atctctattc
     7501 tttttcatct tcgtattttt gttacaaaat tatcgaaaaa aataaacatg tgccatctat
     7561 ctgttggcac atgttttagg atttatggta ctttttattc ggcaatccat tttatttttc
     7621 tacttcttct taatacctct aacacttttg atttataaac taatccaatg catctacttg
     7681 cgcttattaa gctatttcag ctagatagta ccaccccatg cgtcaatgct tgattttcct
     7741 tttgtataac attgtataag caataaagga caaataagtg gtgattacac caaaccattg
     7801 aataagaaaa attctgatac gtaaataaac atgaacttga aaaaattaat gaatcggtta
     7861 gctactacgt agttgtcttt tttctcatac agttctgtta acttacactt ctcttcgcta
     7921 gataataaaa aatcctccaa ctgtattgtc caatataatc ccaggcatct aaactagcat
     7981 tatagaagag acacacatag aatctaaaat aactggtttt aaatgtttct tacaatcaaa
     8041 aaaagctgtt aaatgcactc cacaccttca tactctatca ttttttataa acgatatatt
     8101 tttattgttt ttcgataaaa aatagttgtt ttacaataat tattctgcta tattttagct
     8161 atcaaagata aaagagggat aaaaatgaaa tttaaaacat tgctattaaa atttgtcgtt
     8221 ttaggtataa gtgccgtatt tattttgttc ggcgtacttt tttatactca gatcgctaca
     8281 agcgaaaaag gattcaattt tgattggcag accacattat ttgtttctgt catttacttt
     8341 gcccttctcc tagggatcgt tattgcttat ttcttattga aactattgaa aaaaatcgaa
     8401 gataaccaag ctttttccac tcaaagctta aacatactaa aaaaaatcga acgaaccatt
     8461 ttgtttattg gtttcgcctt ttttggctta cttcctaaat ttatgaaagt agcggattta
     8521 gacgatgctc caggtttgat gttggtagga atcgctgtcg tattcattcc ttttgcagta
     8581 tacacattaa caagcgtgct ggaaaaactg cttgaacatg cgattttact taagacagat
     8641 catgatttga cagtgtgagg tgcgacatgg caattatcgt taatttagat gtagtattag
     8701 ctcaaaaaaa aatgagtgtg actgaattga gtgagaaagt gggcattacg atggcaaaca
     8761 tctctattct aaaaaatgga aaagcaaaag ccatccgttt ttccactctc gaaaaaatct
     8821 gccaagtttt ggagtgtcaa ccaggtgatt tgttgaccta taaaaatgac tcgaatacta
     8881 taccagaaga ataaaataaa gtagaacaaa cagtaaataa aaaataatct gaatgataga
     8941 tgtgtgagac ttttagaagt tatttacgtc tattattcag attttttatt tcgattgaat
     9001 accgttttat ctataaataa gatatgtact gactcataca aagggggcct tttcttctcc
     9061 atgtactatc acttttcctg atacaactgg tttcctgtta cgttgtagtt ggatctgctt
     9121 ttagtataat actttattca ttccaccaga ctgatagcag tttgagcagt ctaaataatc
     9181 atgtagtatt acaggccatt ctgtttcata ccttgaagtg cttaaaactt cagctaatgg
     9241 cccattgtgt taactcttac tccattcttt tttagtaagc tcccatatat actgtaaagc
     9301 cttctatata ttatgtcatg ttgcttttta acatttacta tgtagttttg ataaaatgat
     9361 ttgaataaca gtgatggaca attctttttt atttttaaca ttattttgat aataatg
//
LOCUS       DADQDV010000093         9312 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.096, whole genome shotgun sequence.
ACCESSION   DADQDV010000093 DADQDV010000000
VERSION     DADQDV010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9312
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.096"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..435
                     /locus_tag="J8S10_002616"
     CDS             <1..435
                     /locus_tag="J8S10_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HAZ9631179.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPVQAEQPVVQET
                     VQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQL
                     DSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            complement(759..842)
                     /locus_tag="J8S10_002617"
     tRNA            complement(759..842)
                     /locus_tag="J8S10_002617"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(806..808),aa:Leu,seq:cag)
     gene            1370..1870
                     /locus_tag="J8S10_002618"
     CDS             1370..1870
                     /locus_tag="J8S10_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAZ9631180.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            complement(2060..2404)
                     /locus_tag="J8S10_002619"
     CDS             complement(2060..2404)
                     /locus_tag="J8S10_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HAZ9631181.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(2558..3478)
                     /locus_tag="J8S10_002620"
     CDS             complement(2558..3478)
                     /locus_tag="J8S10_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAZ9631182.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            3665..4156
                     /locus_tag="J8S10_002621"
     CDS             3665..4156
                     /locus_tag="J8S10_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HAZ9631183.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            complement(4180..6555)
                     /locus_tag="J8S10_002622"
     CDS             complement(4180..6555)
                     /locus_tag="J8S10_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HAZ9631184.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            6881..7507
                     /locus_tag="J8S10_002623"
     CDS             6881..7507
                     /locus_tag="J8S10_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAZ9631185.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            7530..8234
                     /locus_tag="J8S10_002624"
     CDS             7530..8234
                     /locus_tag="J8S10_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAZ9631186.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            8426..9259
                     /locus_tag="J8S10_002625"
     CDS             8426..9259
                     /locus_tag="J8S10_002625"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HAZ9631187.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
BASE COUNT         2834 a         1793 c         1656 g         3029 t
ORIGIN      
        1 tactcaggac aacaattaac aatcccaaca gaaggctctg cacaagcagc tgctgaacct
       61 caagcagccg ttcaagaagc accagtccaa gctgaacctg ttcaagctga acaacctgtt
      121 gtacaagaaa cggttcaaac ggaaacacaa gcagcgcctg ttgctgaaac acaacctgct
      181 cctgctgtaa cagaaactgc tgctactcca gcaagtacaa gctctgcaaa agaatggatc
      241 gcacaaaaag aatcaagcgg ttcttacaca gcaacgaacg gacgttacat cggccgttac
      301 caattagatt cttcttactt aaatggtgac tactctgctg caaaccaaga aagagtagca
      361 gaacaatatg ttacttcacg ttatggttct tgggaagcgg cgaaagcatt ctgggaagca
      421 aacggttggt actaagattc attatttgaa cgtttaaaca cattcaaaat atagtaagag
      481 gtcatgcgat ttattctttc gcatgacctc tttttgagtt taagtttagt ctttattcct
      541 taactatcgt ttgccagtat ttcttgtatc agaatctata aatctactat ttgaatcaat
      601 ctattaggtt ttaaactgtc ccaccttcac acaaattttt tttgatttat ttgaatctgg
      661 ttccgttgtt taaaattttt cctatattct tttagataat atgttatttt ctttctcatc
      721 gctccaggtg taccttctct ttataaaaaa acaaattatg cggctaagaa gactcgaact
      781 tccacgaggt caccctcact agcgcctgaa gctagcgcgt ctgccaattc cgccatagcc
      841 gcatcacatc ttttagttta ggattacatg tgttttttgt caagaacata tttttgttct
      901 ttttcatttc tgtacgccct cccttatgcc atctacacaa ataattcatc cgagcaactc
      961 catcatctat tgagggttgg tgaaaaaatc tgttttatcc atatgatcga tttcaatgtt
     1021 aaacgaacga ctctgggatt agtaactatt ttattttttt cttcatttct tttttcctct
     1081 ttttctcgat tcagctatct tctttcattt ggatattgat tatttcttct gttgattact
     1141 atccttctgg aattctagac gctgaagtaa ttcacgtttt ctttcttcta gagatcataa
     1201 gtaacgaatg aacgaacttc aaataatttt tttattgtaa ttcatatttg tattgttcga
     1261 tgattcttaa tacgatatga cacaataaat aaaaataggc atggctattt acaacaatag
     1321 tgctatagta gaaaacaaat gaataaggtt acttaaagag gtgaatacga tgaaactgat
     1381 caaactatgg gaagcagatt taaagaaagc ttatcagcta caaactagct ttggaccaaa
     1441 tgagagtgga tttatcaaca atgcttatgg ctatacattt gctgaatttt tagattatgt
     1501 aaaaaaatgc gaaaaaacgt ctttaggaat cgatcttcct gagagttacg ttcccgcaac
     1561 cgtctttatt ttagaaagtg atgaacatga gtatgtagga atttttaatt tgcgccataa
     1621 actgaacgaa acattaagaa acggcgctgg ccatattggt tacggcatct cccctaatta
     1681 tcgtaaaaaa ggatatgcca cacaaggatt agcattagta ctacaagagg caaaaaaaat
     1741 cggcattgat gaggcacttt tgtctgtaaa taaaaaaaat cttggcagtc ttaaagcaca
     1801 acaaaaaaat ggggctgcga tttatcgtga agatgagaaa gaatactata cgaaaatcaa
     1861 actgatgtaa aaaagaagga ttccaaaagg aaagggattt gaatgtcctt tatcaataga
     1921 acacatttat ttaattaact tataatatag cagacaaaat tttataaaca aagaaacctt
     1981 ttatctcttt tcttctagaa aggataaaag gcttttttgt ttttcctatt tgcttctcat
     2041 agctagtcag ccaagatttc tatcgtatcc ccaacgcaat ccgtgcataa cggctcatct
     2101 tatctgtcgt ccatgctgga taccagacta gtttgacttc tgctttcgtt acttctggca
     2161 cttcttttaa tgcgtcatgg atagattctg ttaaaatatc tgctaatgga cagcccatag
     2221 ttgttagagt catcttaatg actgtttctc cattttcagg attgaattct atatcataaa
     2281 tcaagcctaa attgacgatg tcgattccta attcaggatc aatcaccatt tccaaggcag
     2341 caagaatacg ttctttgatt agttctattt cttgtccaga ccgttcttgg tttgcttcgc
     2401 tcatcgtacg acactcctta acacgatttt tatttatcat actctttttt tagctgcttg
     2461 taaatgagaa tttagaagta agattctcgt ttaaatttat aaaaatgttc ttattagatg
     2521 taatagatta aatttattct aaaataaacc tgattcctca ttttttttgt gaacgatttt
     2581 ttatttctgg caatacgcca gttgttcgat acattttttg ttcgttttca tttgcaaacc
     2641 ggccaaatac tgaatgagtt ggtaaaatat tgataaatgc atcgtcgtcg atttcatgaa
     2701 cgatctgatc aagatcatac atttcgtagc gggtgatgac catcatgatc atgttccctt
     2761 gtttttttga atagccaccg acagacggca gtaatgtcat tccacgtacc atccgttttg
     2821 ctagttcttc tgttacctct tctggcttga cggtaacgat cattgctgtt actttttgat
     2881 gactcgtgtg gatggcatca attacttgag tcattgcata aatggaaata atcgtataca
     2941 aggcactttc ccagttaaag aagaagcctg cgatgactac aatgatacca tttagaatca
     3001 gcatgtagtt tccgactgtt tttccagttg tttgtgaaag tacaagagag atgatatcca
     3061 tcccaccagt tgtaaagccc atttttaaag ataatcctac gccaagacct aataaaacac
     3121 cgcctactag ggcattcatc aaaatattat cagtgatctg tccgactgga agcagcatcg
     3181 tcatcaccga tacacataca acattcacaa aactaaggat cgttgctcgt tttcctactt
     3241 tgagaaaccc taatacaaac acagggatat tcaaaagaaa aataaatgtt cctgtgtcta
     3301 tcttgatatg aaaccattca tataaaagcg aggaaatgat ttgagcgatc ccattcatcc
     3361 ctgcagaaaa gacattggct ggaatcaaaa aataatttaa agcgaccgca gcggtcaatc
     3421 cggttatcaa aataaccact attttcttta atctttcatt tttatgatac gcagtcataa
     3481 ttttactcac aagcacctct cccctacttt ggtattccaa atgtaagaat aacagtttat
     3541 ctattaaaat aaaatacttc gaactcaaat gagaagaatt ttagcaaaca ggtaagaatc
     3601 tgccctaatc ctatgataag atagatgtat ggtaaatatt tatatgtata tcaggagggt
     3661 tcctatggca aaagatgcta gcttcgacat tgtatcagaa gtcaatacag aagaagtaaa
     3721 aaatgcgatt cagcaaacaa caaaagaatt gtccaatcgc tttgacttca aggattctac
     3781 agtagaaatc aaattagaga acagcaatct agttgtattg agcgatgatg atttcaaaat
     3841 cgaacagatc aaagatgtat tatttggtaa gctgatcaaa agaaatgtgc caatcaaaaa
     3901 tatccatttt tccgaatcag aacacgctct aggtggcaaa gctcgacaaa ctgccgattt
     3961 ggtcaacgga atcgatcgtg aaaacgcgaa gaaaatcact acagctatca aaaatgaaaa
     4021 actgaaagta aaagcacaaa tccaagaaga tcagattaga gtgacaggta agaaccgtga
     4081 tgatctacaa gctgtgattg ctttattacg taaacttgac ttaccaatcg agttgcaatt
     4141 cactaactat cgttaatcaa aaaacgaggc tgacgtctgt cattcctcgt ttttttgatt
     4201 tactgcttct tttgataacc aaaaacgctg tattccttct tccaattccc caacacttcg
     4261 tacttctctt gctgtttgcc aatgttgtgg gaataaacgt cgataagaaa aactagaaaa
     4321 tcgttgatct gccaatacaa cgattccttg atccgccatg ccacgaatca ctcgaccacc
     4381 agcttgcaag actttgttca ttccaggaag ctgataagcg taagcaaatc caaggtgttc
     4441 cttctcatca taatatgatt tgatcagttc ctgctcatga ttcatctgcg gcaaacctac
     4501 acctacgatc atactgccga tcaatcggtc ccctctcaaa tcgattcctt ctgaaaaaat
     4561 cccgccaagt acgcaaaatc caatcaatgt ttcagcggga tttgtttgaa attttgttaa
     4621 aaatcgttcg cgttcttcct cattcatgtc cgtttcttgg attagcacat tgctgtcggg
     4681 atattgctgt ctgaatgctt ccaccgcaag atctaaatat tgataagaag gaaagaaaac
     4741 gaaataattc ccgacctttc catcagcaaa agcatgaatc gtctctacta attttgccag
     4801 actgtgttcc ctttttcgat aagtcgtctc taggtaattt gcgatgaaaa cttgctggtt
     4861 tccttctggg aaaggactcg gcagtttgta agccagactt ttttgtcccc ccagtgtttc
     4921 ctgataataa gagagtggtg aaaaactagc agaaaaaaga atactgcttt ttcctttatc
     4981 caacgactgc tcaagaaaca agcttggatc aatacaaaac tcttttacta tcagatcgcg
     5041 atacgttttt tcgactgttg tttcgtagtg atcatcataa aattcactga ccttcaaaaa
     5101 atgaagcaaa tcaaaataat aaggaagcaa ttgttcttgt gatgggtgct caggaaattc
     5161 tgccagccat tctttaattt tttcgcttaa ttgataacct gcctttacta aagattcagc
     5221 cggtgctttt tgatgatgat aatcccaatg atcttctttt gctatttctc ggatcgaatc
     5281 aaattctttt aatagtttgt tgaaacggcg atgaagtttt ttgaattcct ttggtatagc
     5341 ttccttactt cgtttcgttt tttcataaga tagttctgcc gaatacatct ctcgggaacg
     5401 attcaccaaa ttatgtgctt cgtcaatcaa aaacagatag tcctcgtttt tttcatcttc
     5461 aaaaaaacgt cttaaataaa cagttggatc aaataaataa ttgtaatccc caatgattac
     5521 gtcacaccag atactgacat ctaatgatag ttcgaaagga caaagtgtat gctttcttgc
     5581 ataagtttcg atgacttcac gagtgatctg attctcatga ttcaaaagat cccataaacc
     5641 ttcattaatc cgattgtaat aaccattggc atatgggcac tgatctggat tacaggtcgt
     5701 ctcatctaaa aagcagatct tgtctttcgc cgtcaaagtg acacttttta cttcagctcc
     5761 tgtatctttt aatgctgtca tagcatcttc agctacttgt ctagttattg ttttagccgt
     5821 tagataaaag atcttttctc cctcttcttc ccctacagct ttcaaagcgg ggaataacgt
     5881 agagattgtt tttcctgttc cggtaggtgc ttctacaaac aatttctgtt tcgtacggat
     5941 cgttttataa gcagctaccg ctagttcacg ctgacctttc ctatactcat catgggggaa
     6001 tttcaaagcc atcaaagagg cattgcgtac agtgcgccag ttttcttgaa aaacaagcca
     6061 ttctttataa tcttcagtca gctttttaaa aaaagtttct aactgctctc ttgtctgatg
     6121 ttcaaccttt ctcgtgatca cttcttctgc cgtctggaag taagtcaatt gcagatttat
     6181 ttcttgtaaa tcatgttctt gactatagat ataggcatac acccttgctt gatgaaagaa
     6241 aagttccact tgttctggtt ctaaatcttc aaatcgtggt tcggaggttt tgatttcatc
     6301 tatataataa ataccgtctc ttttgaaaat accgtctgca cggccttcaa cgatcaggta
     6361 atattcatct aattgaactg ttgtttttaa aaagacttct ttttcatagt tttctcccgc
     6421 atctttttgg agcttgcggt ggattctcgc tccttctaat gcagtatggt tacttttttt
     6481 acgattgtcg atacttccac gtcgcaaaat aaattctact aagtgccgca cagatatttt
     6541 tgactgtttg atcatttcca ccacctcttt ctctctaaga ttacctgaaa aaacctagtt
     6601 tagcaaaaag agctctcttt ccaaacataa aaaaacaccc tgctgattag gcagggatat
     6661 aggatataga atttggattt ttggatgaat ctaatgtaac aaggacatat taaaatgcta
     6721 tgaaaactta ctttccttct ctttagaata tccaaatact tttcatatag tctgataatt
     6781 cagataagta aagagaaata agtacctgtt tttgtttcct agcaatgaat gcgttatact
     6841 aatggatgaa agaagttttg gctatcaagg aggaatgcac atgcatatcg aaagattaaa
     6901 aacaggaatg attgaagaaa actgttattt ggtctacaac gaagaagcac ttttgatcat
     6961 tgaccctgga gaagatgcgg aacgaatcaa acaagaaatc aaaaaaacaa accaacagcc
     7021 ggtagcgatt ttgcttaccc atactcacta cgatcatatc ggtgcagtgg aacctttacg
     7081 cgcgtattat caaatcccag tttatgtcag cccactagag caaaaatggc taggtgatcc
     7141 gattttgaat ctttctggac tcggtagaca tgatgatatt gctgatgtta ttgtctcgcc
     7201 tgcagaatat gaatttgaaa tgaaaactta tactttagga aacatgtctt ttcgcgtcgt
     7261 ccctacccca gggcattcta taggaagcgt cagctttatt tttgatgatt ttgtcgtttc
     7321 tggcgacgcc ctgtttagag gaagtatcgg tagaaccgat ctgtatacag ggaatttaga
     7381 acaattactt catagtattc ggacccagct gtttgtatta cctgatgaat ttgcagtcta
     7441 tccaggacat ggcgatgcaa cgacgattga acaggaaaaa aggacaaatc cttttttcaa
     7501 tcgttaaaac gacttaggag gagaataaaa tgacagaaac tacactttat atcgtacgac
     7561 acggaaaaac gatgttcaat acaattgaac gagtacaagg ctggtgtgat acacccctca
     7621 caaagcaagg acaagaaggc attcattatt taggtcgcgg gttaaaaaat gtcgactttt
     7681 catttgctta ttctagtgac agtggtcgtg caatcgaaac tgcccgtatt attctaggag
     7741 aacattctaa gggaaaagaa attccttatt ttattgaaaa aaggattaga gaatggtgtt
     7801 tcgggtctct tgaaggtgga tatgacatgg aaatgtgggg tgtgatccct cgtgtattga
     7861 attttaaaac atatgatgaa atgtttacca cagaagtttc ttttgaacaa attgctaatg
     7921 ctgtatacaa cttagatacc gctgggtggg cggaaactta tgaaacattg cgagaccgtg
     7981 tatggacagg atttgaagat atcgcccatc actgcgaaaa aaatggtggt ggaaatgttt
     8041 tagtcgtatc tcatggtttg acgatcgcct ttttgcttaa tctgatcgat cctaaacagc
     8101 ctgttcgtgc tgggctttta aatggcagcg taacaaaggt cacttatgca aacggtcgat
     8161 tttctatcca cggcatcaat gatacgtctt atatcgataa cgggaaaaca catagtcgcg
     8221 actcgtttct ataatgggga tattttaatt tttaccagag aatcataaaa ggcaaagtct
     8281 gaacgagggc tttgtcttct tttttctctt cgtgtactta tctgctttat ttctcaagtt
     8341 tttcttaata ttaaaaaaca gattgggttt ctcaaaaaat aacggtatac tataagatgt
     8401 atcttaattg ggaaggaagg aatttatgtt ttttgcaaat attatcaaag cagtgattct
     8461 cggtattatt gaaggaataa cggaatggct gcccatcagt agtactggtc atttgatcct
     8521 agcagatgaa ttcatcaaac tggatgccag ttcacaattt atgtcgatgt tcaatgtcgt
     8581 tatccaatta ggggcgatct tggctgtcgt cgttctttat tttcacaagt taaacccatt
     8641 ttctccaagt aaatcaacgg tagaaaaaaa agatacgtgg acactttggt ttaaagtgat
     8701 cgttgcttgc ataccagcca tcatcattgg tttgcctttg gatgattggt tagaagcaaa
     8761 tttccacaag ttcttaccag ttgccattgt tttgatcgtt tacggtattg cctttattat
     8821 tgtcgaaaaa cgcaacaaaa acaaaacacc tcgttggact tctctgaatg actttacgta
     8881 ccaagcagct cttcttgttg ggttattcca agtcttggca cttgttcccg gaacatcccg
     8941 ttctggcgca acgatcctag gatctatctt gattggtgct tcgcgttttg tcgctacaga
     9001 gttttcattt ttcttaggga ttcctgtcat gtttggcgca agcggcttga agatcgtcaa
     9061 atatttagct gaagggaatt cattcaaaat ggaagaaact gttgttcttc ttgtaggaac
     9121 attcgtatct tttgtggttt ccgtcttagc tatcaaattc ttactaagct atttgaagaa
     9181 aaacgacttt accgcttttg gctggtatcg tattatcctt ggtatcattt tgattggtta
     9241 ttggtttatt gcaatgtaga aaaaaccaga acacttctct tatttgagaa atgttctggt
     9301 tttttatttt ct
//
LOCUS       DADQDV010000094         8546 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.097, whole genome shotgun sequence.
ACCESSION   DADQDV010000094 DADQDV010000000
VERSION     DADQDV010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8546)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8546)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8546
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.097"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(132..1085)
                     /gene="menA"
                     /locus_tag="J8S10_002626"
     CDS             complement(132..1085)
                     /gene="menA"
                     /locus_tag="J8S10_002626"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HAZ9631188.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFALVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(1098..2201)
                     /locus_tag="J8S10_002627"
     CDS             complement(1098..2201)
                     /locus_tag="J8S10_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HAZ9631189.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            complement(2291..3226)
                     /locus_tag="J8S10_002628"
     CDS             complement(2291..3226)
                     /locus_tag="J8S10_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HAZ9631190.1"
                     /translation="MKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSESSTAQSST
                     AKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKYDNVNENG
                     ESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSSESFQNYA
                     QQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGKVTESNFD
                     YIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPANVEVVTGA
                     THSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            3528..5462
                     /locus_tag="J8S10_002629"
     CDS             3528..5462
                     /locus_tag="J8S10_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAZ9631191.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            5919..6335
                     /locus_tag="J8S10_002630"
     CDS             5919..6335
                     /locus_tag="J8S10_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HAZ9631192.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            6349..6915
                     /locus_tag="J8S10_002631"
     CDS             6349..6915
                     /locus_tag="J8S10_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HAZ9631193.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKQDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            6938..7924
                     /locus_tag="J8S10_002632"
     CDS             6938..7924
                     /locus_tag="J8S10_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HAZ9631194.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(8079..>8546)
                     /gene="scm"
                     /locus_tag="J8S10_002633"
     CDS             complement(8079..>8546)
                     /gene="scm"
                     /locus_tag="J8S10_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HAZ9631195.1"
                     /translation="TSASSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSSDSSTTTS
                     DSTDTSASSDSTDTSSTTSDSSDSSTSSDSTDTSSTTSDTRHASVSFSKTSSDNRTNF
                     NLTNKTSNDNGNKSKRALPKTGSQSNNWITLAGVILLVIGLRITFMSYKKSKR"
BASE COUNT         2519 a         1644 c         1735 g         2648 t
ORIGIN      
        1 tgataaacgg tgttcaaaag cttgcatctg cggtaataag cccaaccaaa cgaaaaatat
       61 aaggagctat ttttatttgg ctgttcttat tacttgatgc agggcagttt tttcacaacc
      121 tcttcatgct gttaaatggc ttgcataatg attgttagta atagccccaa tacataactg
      181 gcattgaata agaccatatt tttgatggaa tagctgaaac tgataggctg gggtaacgtt
      241 tgcttgaatt gatccaaatg cttcttcaca attggcaagg tcaagaaggt gaccaagatc
      301 ggccattcat agataccgct caacaacccc attaaaatca cgaaatagca agcatacatc
      361 aatagctgga ataagactgt tcccgcagga cgtccgatat aaaaaactag tgtatagcga
      421 tgattttcaa tatcacggtc aagatcccgc aaattattag ccaacatgat attggcaatc
      481 gtaaacacca agggtaagga agctaatacg attgctgcta tagcccaaag atttcctacc
      541 aaagcaaatt gtccagatga aaagttgact gtcagatcat agacatctga accgaatgta
      601 ttgacataaa cgaccatggc aaaaattcca aggcccatag tcaccccact gaaaatttcc
      661 cctaaaggca ttcgagataa aggaatcggt ccgaatgtat agaatactcc aataaaacaa
      721 cagataaatc ccatcaaaag taaaagccaa cccgtattga tcgttagaat aacgccgata
      781 acaaaaacaa atgcaatcat agctaaaatc atgtttcgaa tcaatacagg agatagattt
      841 ctgcggccaa tgacattttc ttcatactta tatacttcag aatgagcctt ttcataatcc
      901 atgtaattat tgatagcggt agtcgctaaa tcaaaaacta gcattccaat aaaaaataaa
      961 aaagtgttta gccaatgtat ctcatgaaaa aaagcgatag agaataatac ccctaccgca
     1021 aaaggaaata cactagccac ctttgttcgt atttcaacta cttctaaaaa gatttttagt
     1081 gtcatggttc gtactcctta ttttagttca gaacggtcac ccatcgtgta atgggagtcc
     1141 tccgataatt tgaaggtgtc tttgattgga tcggtcacat atactttatc gtcttttgtc
     1201 acgaagatcg cttccgtccc gttattcaat tcgctttcga cgtattccag tccttttttc
     1261 acacccattg aaaagactgc tgtagacaac ccgtcaccat caattgattt atctgttatg
     1321 atcgtgacac ttgcgatatc attgtcgaac ggataacccg tttttggatc aaacaaatga
     1381 tggtattttt tgccatctac ttctaaataa cgctcgtaaa ttccagaggt aactaatgtt
     1441 ttgttccgtt ctttaataga acctaaaaca gatccgcgag ccatgttcgg atcttggatg
     1501 ccgactgtcc agtcttggtt ttcgcctctt gggctgtggc ctaagacata gacattaccg
     1561 cccaagtcaa cgatggcagt ggtcactcct tgttttttca agactttcac tacttcgtcc
     1621 gtaatgtaac ctttggcgat tgcacctaaa tcgatgatca ttcctttttc ttttagataa
     1681 acagtttttt ctttgtcatt tagttcgatc ttatgataat ccactaattt caatgcctga
     1741 tcgatttctt cttgggaagg ttttctggcg tcatcaaaac cgattcgcca taattgtgtg
     1801 attgcaccaa tcgccatatc gaatccgcct tgagaatctt ggctatattc gtaggcccgc
     1861 ttgactaacg tgtagacgtc atcagaaact tttactggtt tgatcccagc ttgctcattc
     1921 acttcatcga tctcagaacc tttttgattg atcgtgattt tatcaccaag ttcttttact
     1981 cgatcgaagg caggtttcaa tgctgattct ttgccttcat catacacacg gatacgaacg
     2041 taagtcccta acaagaactg ttcatcagaa tatggatctt tcaatatctt ggtagctgct
     2101 gaactttcag tggttgtttt atttgctgag ttgctgcagc cagttagcac cataaaagag
     2161 atgcccagtg tgattaagga aaatagtagt tttttccgca tctttttcct ctcttcattt
     2221 tgaaaggtga gacgactgcc taatctggct atcgtcccac cctccaactt ttattagtat
     2281 gattatgtga ttatttttct gttacgatat tatctacttc gattgtttga gtgtcgcctt
     2341 tttcagctgc attcactaat tgttgtgcgt acatgatgaa tgaatgtgag ctgtgtgtag
     2401 cacctgtaac aacttctaca ttagcaggtg agccatcttc ttcgcccatt gctttgacga
     2461 attcgtcgtt cagagtaggg atgtaagttt ttggttctgt accgcttttt gctttcatat
     2521 tttcattata ttctgtatca tcttgttttg atttaccgtc tttgtcgata taatcaaagt
     2581 ttgattcagt tactttgccg ccagcaactg tcatttcgaa ttgcacacgg tagccgttag
     2641 agtagttctt ttcttcaagc ttgtaagtgc cgtctttcaa atcagcacca ttgtcgattt
     2701 cgattgtatc tgtgttacca gcttgagcag cttggatcaa ttgttgtgcg tagttttgga
     2761 agctttcaga tgagtgagta gctccagtta cgacttccac accgcttgcg ctttgtgctt
     2821 ttaagaattg gtcattcaac tcaggaatgt atttttctgg gtttgtgcca gattttgctt
     2881 ccatgttttt gttgtattct gcatcttttg tttttgattc gccgttttca ttgacgttat
     2941 catattttga ttcagtgatt ttgccgtctt ttacaaccat ttcaaagact gcacggtaac
     3001 catttgaata atttttttct tctaatttat atgtgccgtc ttgcaaatct ccgccagcta
     3061 caacttttgc agatgattct gttgtgcttt ttgcagtcga agattgtgct gtagatgatt
     3121 cagaagaaga gtttgagctt ccgttgtcat ctgcgccgca agcgcctaac actagagctg
     3181 aaaatgctaa tacggcaaat ccagttacaa aacgtttttt cttcatttta ataccccacc
     3241 attccatttc tagtccacaa tttttctttg tgattcatta tacattctaa tctttttagc
     3301 ctataagtca actatttttg ataaataacc catgtaatat ttcaaacgtt ttctttcagc
     3361 aaatttcgtg aaaaaacgct ttattttaaa atttgaaaaa aatccaaaag gagttagaca
     3421 aaagaacaga acatctatat aatatatgga gattgtgtaa taagtatcaa actaaaagaa
     3481 ttatcatata ttcattatat agatagtcta taaggagcgg atgatcaatg gcaaagcaaa
     3541 atattgtcgt tgtaggagca ggatatgccg gtgtttcagc tacaaaatac ttggcaaaga
     3601 aactgaaaaa agaagatgta gcaattactc tgatcgatcg tcattcgtac catactatga
     3661 tgaccgagtt gcatgaagta gctggcggac gtgtagaacc agaagcaatc caatacgatc
     3721 tgcagcattt gtttgctcgt caaaagaatg tacaacttgt cacagacact gtaatcggta
     3781 tcgataaaga acgaaaaatc gtcaagacca aattaggttc ctatcctttt gatcagctga
     3841 tccttggaat gggcggagag ccgaatgact ttggtacacc tggtgtcaaa gcacacggat
     3901 tcaccctttg gtcatttgaa gattctgtaa ggattcggga acatattgag aagacagtag
     3961 caaaagctgc attggaacca gatgatgaac tgcgtaaagc catgctgact ttcgttgtct
     4021 gtggttctgg atttaccggt attgaaatga ttggggaact gatcgactgg aaaaatcgcc
     4081 tagccaaaga ttataaatta gatccaaacg aaatcacact gatggtcgta gaggcaatgc
     4141 cgacgatctt gaatatgttg gatcgaaatg atgctgcaaa agctgaacgc tatttgcgta
     4201 agcacaacgt ggaattatta ttgaatgcac caatcgtaga agtggctgct gatcatatca
     4261 aattgaaaga cggacgcaac attccgactc acacactgat ttggacagct ggtgtcaaag
     4321 gaacttctga cgctgctgac tttggattag aatcagcacg cggacagcgg ttgatcgcca
     4381 atgaatatat gcaggcaaaa ggctacgaag ataaaaacat ctatatcatt ggtgatttag
     4441 tcttttatga agaattccca ggaacaccga caccgcagat cgttcaagct gctgaacaaa
     4501 caggacacac agccgcagcg aatatcgtgg cttcgatcaa aggcggagaa aagcataaat
     4561 ttaaaggaaa ctatcaagga tttatggttt ctattggtgc caaatggggg gtagctaacc
     4621 tatttgataa gatccattta agcggatttt tagctatcgt aatgaaacat atcgtgaatt
     4681 tgaaatactt ctttgatatt cgttctggtt attatatgtt ccaatattta atgcatgagt
     4741 ttttccatat caaagatgat cgcaacgtga ctcgaggaca ttcttctcgt tacggcaatg
     4801 tcttatggag tgtgccactt cgtattttct atggtttagt ttggttcgtt gaagcttcca
     4861 aaaaaatcat tgggaatggt gaagtgttca aaccaagtac ttggtttggt gaaggatcat
     4921 ggttcactgg aaacagtgtg ttcccttgga catgggaata caatgtaaca gatgttgcca
     4981 gtggtgcttc tgctgctggt gatgcaacca cagctgccag cggagcaggg gcaagtgccg
     5041 gagaagcagc gactcaagct gcacattttg gtttgagtta tgcatacggt gaagaaccaa
     5101 tggctgtgat tgagaagtca ccagactggt tcacaaagat catgcaagtg atcatgccaa
     5161 acaatgatgt agcaatgttc ttccaaaaat tcatggtatt ctttgaaatt gccttggcat
     5221 tagcattgat tgctggatta ttcacatggc tatgcagtgc gacaacgatt gtattggtga
     5281 tcacgttctg cttatcaggc atgttttact gggtaaacat ttggttcatt tttgttgctt
     5341 tcgcattgat gaacggttcc ggacgtgcga ttgggttgga tcgctgggta attccatggc
     5401 tacaacgtac actaggtaat tggtggtacg gtagaccaag ttcccagtac ggcaagaaat
     5461 aaatagataa agaacgttat ttgaatgcaa gatttcaata gaaaggggct gagacaaacc
     5521 gtcacagcct cctttttatg taaaattaaa ggaataagat gcccgagata agcctccatg
     5581 agcaagacac aggtgtcaca acctctgtta caacctcttg ttataaacgg tgttccagaa
     5641 gtagcttctt cgaaaaataa gccgaaattt cacaaaaact tgaaaagtaa ttttcgtaaa
     5701 ttccttctta tttcttgaag ttgcccactt ctgtcacaac ctcttgttat aaacggtgtt
     5761 ccacctgctg cttctcggta ataagcccaa agaattagaa aacatggaaa gctgttttct
     5821 attcttcgtt cttattactc aaagcaagac acaggtgtca caacctcttg tttttatgct
     5881 aaaattgggt gagttaatct ggaaaaagga gaacaaaaat gagccttaaa gaatttgctg
     5941 aaaaaagtct gctcaaacct tgggatgttt ttattatttt gcttttgact gttctttctt
     6001 ttttaccagt catgattttt ggtcttcagc aaaacaccgc aacagcagaa aaagaagcgg
     6061 tactgcgtgt ggatggcaca gaaatcaaaa cattcccttt gatggctgga gaagagagca
     6121 acacatatac ttacaaagat gaacacggag attataactt gatcgagata gatggcgatc
     6181 gagtacggat aaaagaagca gattgcgatg accagatctg cgtacgtcga ggctgggcaa
     6241 cgaaaaatgg cgaaaccatc gtctgtttgc cacataaatt agtgatcgaa gtccgttcaa
     6301 cagatggagg tgacgaagac agtctgattt attagacctt tacacaccat gagtaaatta
     6361 caaaaaatga tttatatttc gctacttgtt gcacaaggag tgatcattgg tttattggaa
     6421 aatatgatcc cttatccttt ttcttttgcg cctggtgcaa aactaggctt agccaatcta
     6481 atcacgatcg ttgccatttt taccatgaaa aaacaagaca gcttcttact actttggcta
     6541 cgactattcc tgactacttt gctaggcgga acgatttcca cattccttta tagtatgagt
     6601 ggtgctttgc ttagttattt tggaatgtta ttggtcaagc aattaggacc aaaacgtgtc
     6661 agtatcatcg gaattagtgc ggccggcggt ttcatgcata atgtcggaca gcttttgatg
     6721 gcttctttca ttgcacaatc atggacagtc atgttgtact tgccagtcct ttcagtttta
     6781 gggattttat cagggattgc aatcgggatc gcagcgaatt atcttttacg acatgtgcag
     6841 acacttcaac gattccaaaa agattatgag cagggaacca aacaaaaatg gagcccaatg
     6901 tttaccaaaa aataatcgtc acacaaggag tttttttatg aagctacatc caatgtggga
     6961 aaactatcct gctttaagta aagaattgac agaaacacta aaacggatgg aagaaactgt
     7021 ccgcctgaaa aacaaacctg tcgaacaagc aatcaaagaa acgatccatg ccggcggaaa
     7081 gctgttgcgt cctgcctatc agctattgtt ctcacaattt ggaccagagc aagatcgaga
     7141 caaagccatc gctttggcag cttctatcga aatgctccat acggccacac tgatccatga
     7201 tgatatcgtt gatgaagcgg atctgcgacg tggtcagcct aatatccgta gtcagtttgg
     7261 taatgtcgtt tctgtctatg caggagacta tttatttgtc tgctgtttta aactattgtc
     7321 tgattactcc acttccttga aaagtctcca attgaattct cgcagtatgg aaaaagtatt
     7381 gaatggcgaa ttagggcaga tggatgatcg ctataattat gaactttctg taaaagaata
     7441 tttggaaaat atttcaggta agacagctga actgttccaa ttaagttgtt ctgttggcgc
     7501 ttttgaaagt ggaacaagcg agcgcttcgc aaaaaaagca ggagatatcg gactttctat
     7561 cgggatggcc tttcagatta tcgatgatat tttagattat acaaaagaga gccaggaaat
     7621 cggcaaacct gtactagaag acatgcgtca aggggtctat tctttaccgt tgatctactc
     7681 tttgcaaaaa aacaaaccaa agctactacc ttatttagag aagaaagcgg caatgacaga
     7741 agaagatgtc gacgccgtac gcaaaatcgt tgaacataca ggaggcgtgg aagaagctag
     7801 gaagttagcg gcctcttaca cagaaaaggc tttgaaggaa ataaagaaat tacctgccac
     7861 ctctcttcga acaaaagaga atctcttttc ccttacccaa ctgattttgg atcgcaaaga
     7921 ctgaataggg aaaggttcga tacgtaaata aatttctcag aaggaaatct acgtgttttt
     7981 tgacaaattg aattgtagtt cttgtattta tgataaaaag caaaaataaa gagcaacgtc
     8041 cgttagcgac gttgctcttt tttatcttga atattttttt accttttcga tttcttataa
     8101 ctcataaaag tgattcttaa accgattaca agtaatataa cgcctgcgag tgttatccaa
     8161 ttattcgatt gacttccagt tttaggaagt gctctttttg atttgtttcc attgtcattg
     8221 cttgttttat tagttaagtt aaagttcgtc ctgttatccg aacttgtttt tgagaaggag
     8281 acacttgcat gacgtgtatc gcttgtggta gacgacgtgt ctgtactatc gcttgaagtt
     8341 gatgaatctg agctatcact tgtggtagag gatgtatctg tactgtcact tgaagctgac
     8401 gtgtccgtgc tatcacttgt agtggtagat gaatctgagc tatcacttgt ggtagaggta
     8461 gtatctgtac tgtcacttga agctgacgtg tccgtgctat cacttgtggt agaggtagta
     8521 tctgtactgt cacttgaagc tgatgt
//
LOCUS       DADQDV010000095         8493 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.098, whole genome shotgun sequence.
ACCESSION   DADQDV010000095 DADQDV010000000
VERSION     DADQDV010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8493
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.098"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..173)
                     /locus_tag="J8S10_002634"
     CDS             complement(<1..173)
                     /locus_tag="J8S10_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009325336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAZ9631196.1"
                     /translation="MATKIADELENHVLETGMQKITTHASITAKPFFEKRGYKVINEQ
                     TVELRGQLFTNFL"
     gene            complement(593..1714)
                     /locus_tag="J8S10_002635"
     CDS             complement(593..1714)
                     /locus_tag="J8S10_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /protein_id="HAZ9631197.1"
                     /translation="MDKYNVKTSFQKWFSAINFSGLSENSQSLISDFDFYSKKLDFQT
                     TLKVLLHAVYEELPSYREIDRAFLDQRLCKELGIDSLCYSSLSRRAPEIKQEVLMEIF
                     TQLVARISAQQPSSKTTSLQLIDSTTIPLNKAWFPWAKFRKTKSGIKLHLNLCYLDKT
                     NQYPESFTMTNASEHDRNHLEVLVDKTQATYVVDRGYFDYKLLDKLNRDGYFFVTRTK
                     SNTKITILDQIEVADTTTRDGTIISDQQVILVGGVNHVTERFRLVTVLTKGQKILRMV
                     TNLFDVSPNEVADMYQARWQIELLFKHLKQNLTIKRLYSHSEQGAINQVILTLIATLL
                     TYVIKIELNTTATLFQLKRTFHYLMFEPAEEWFKRYRPG"
     gene            2042..3451
                     /locus_tag="J8S10_002636"
     CDS             2042..3451
                     /locus_tag="J8S10_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HAZ9631198.1"
                     /translation="MDDIKTIKHLRNNRDQSIDQIRKAMNINWRTAKKYADSDQLFIT
                     DPTRKNKSMMDDGWGEIIGSWLEEDLRLRRKLRRTAKAIHEQLKPLGFPGSYRTVCVY
                     ISQWKKQRYDETNYQAVDRLDHPIGEAQVDFGTMEVMHEDHMKDIQLLIMSFPYSNAT
                     SASAMPAQNQECFLEALKQLFNQCGGVPKTIRIDNLTPAVKKTKSKFEEAQLTDEFLR
                     FTIHYGCDVQVCNPRSGHEKGHVENKVGYVRYNFFSTSPIMDSFESLNKQLEEQLKAD
                     RKRTHYSKHQLIEDLWKKENKALHSLPQEDYPIFKEVEAKLNRYHEMKLDQTVIHIPK
                     AYGYSQLTVVLTWNKFKVLTPHGEILMNEYRPYMNKKRLIPWSDIMKQWSNKLNVVSY
                     SRYWKYLPARLQNYLAIDNNHLKYRRIKQLLSLLATYDIQQINEQFYELVVQEDAPSD
                     FDVNWSNYDALTKTGGVQK"
     gene            3448..4176
                     /locus_tag="J8S10_002637"
     CDS             3448..4176
                     /locus_tag="J8S10_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAZ9631199.1"
                     /translation="MIGQTLEDYCKKLRLSHIITNIPRASFEAPEQFITDLFRLELET
                     RQQIKLERMEKLAKFPVPKSLKNYEWHEDIFLPSHLDKETLVSLDFLKRQENIVCVGS
                     PGTGKTHLAIALGRKACSEGVSTKFFRVNNLVEQLENALKKQQLASFKKRFETTELII
                     LDEMGYLPLTKEGAELLFQLISDWYEQKSIIITSNLEFSQWNRVFMDSRLTAALVDRL
                     IHHAHIISFKGESFRLKNSLSKSY"
     gene            complement(4304..5215)
                     /locus_tag="J8S10_002638"
     CDS             complement(4304..5215)
                     /locus_tag="J8S10_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAZ9631200.1"
                     /translation="MKIKIERSNKEKIPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GIYKNFTAIDQHTTHEKVVVKEKIVNTSGVENFTVDFVKEYFSWKNNKEVIEKRMTNL
                     EQYLTEEGLALSQDMVRADIPTSSEVVSVKILDVEKHSEEFVVSFVVDQKITEGKKTQ
                     SISSAYRLMIFEDEKGNHIVTSLPTMIGKPEKAKHKVRQVKSDSKIDSKTTEEITEFL
                     ETFFRLYPAASEKELEHYVEKDAMQPINTNLKFVELVNPIYKQKGKAIQVIVGVEYLD
                     ELSKTTSVFQYRLKLYKNENWTISNCE"
     gene            complement(5232..6239)
                     /locus_tag="J8S10_002639"
     CDS             complement(5232..6239)
                     /locus_tag="J8S10_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HAZ9631201.1"
                     /translation="MNLKKLSIISLTFLTISFVGILMCVGLLFGEDGEGSGSSGTSPG
                     GSSVSEVVLKHRSMVEKYAKESDITEYVSILLAIIQVESGGTMEDVMQSSESAGLSPN
                     SLSTEASIKQVCLYFSSLVKCSKELGCDQDSIIQAYNYGDGYLDYVAKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENSGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGSSPGTGFDCSGLTQWCYAKVGLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLIFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTDSYWQQHIIGAGRYK
                     Q"
     gene            complement(6236..8365)
                     /locus_tag="J8S10_002640"
     CDS             complement(6236..8365)
                     /locus_tag="J8S10_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAZ9631202.1"
                     /translation="MKKKLFRIVGIVFISIVTLTVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAKSIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRTVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTKIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEGRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKRAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRTFAFGGGAAVGGKLATSSTKGKGSSKINRVSNRKNHSARSINELNSDLKK
                     QEQPVGTKKESRINLVGRKVGKVLDTKEIVKDKAKQAKNQVTDAPTNLKYSLHKGMEK
                     TKKVPEDFKRGPFEEKANRGELREKQRQRRDAKMDEKRKVLNEAWNRHEKGRENVPIK
                     KEIKPQKNELPENRSLKPRVQVHSNPEIKRKLSSQEVIPNGSTQPLSKNNSFQQVKQR
                     FTFPKRTNQQVQRKKNTRPKPKPGEKR"
     gene            complement(8370..8477)
                     /locus_tag="J8S10_002641"
     CDS             complement(8370..8477)
                     /locus_tag="J8S10_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631203.1"
                     /translation="MQDLYGRVGVVQVHPVFEELFHAFDTRPPVQERME"
BASE COUNT         2599 a         1728 c         1486 g         2680 t
ORIGIN      
        1 attaaaaagt tagtaaataa ttgccctcta agttccacgg tctgttcatt aataacttta
       61 tatcctcgtt tttcaaaaaa tggctttgcg gtaatggaag cgtgggtagt gattttttgc
      121 ataccagttt ctaaaacatg gttttccaat tcatctgcaa ttttagtcgc aatacctttt
      181 ccttgatggc tatgtttttg tcacaacttc agtattcctg taacaatacg gatttcagta
      241 tacaacaaca gcttttgaaa agatacttgc aaaaggatta agatatctat gacctgctat
      301 gctcactgat gttgaaaaga atgttttatt aggattgagg taagcaagat agtgaatatg
      361 tccggaaagc ctgtaaaata aggcttttcg gacatatgtg aagttataaa aagatagcga
      421 aaaatctatt tagtatcact aatgttgcga acatatcgtc agaatagtct gacatttatt
      481 tcttgctaaa aatttcaaaa aagtcaagtg ctgacgcagc ggatgactat tttccagaaa
      541 attttagtat gtattcaaaa atcaaacgtg acaacagcta ttaactacat cctcatccag
      601 gtctgtaacg tttgaaccac tcttctgcgg gctcaaacat taagtaatgg aaggtacgtt
      661 tcaattgaaa cagcgtcgct gtcgtattca actcaatttt tatcacataa gtgagaagcg
      721 ttgcgattaa ggtgaggatg acttgattta tcgccccttg ttcactatgt gaatatagtc
      781 gtttaatggt cagattttgt tttaagtgtt tgaacaacaa ttcaatctgc caacgggctt
      841 gatacatgtc ggccacttcg tttggcgata catcaaagag attggtcacc attcgcagga
      901 ttttttgtcc cttggtaaga accgttacca acctaaaacg ctctgtcaca tggttgacac
      961 cgccgacaag aatcacttgt tggtcactga ttatcgtccc atcacgggtt gttgtatctg
     1021 ctacttcaat ttgatccaag atggtaattt ttgtattaga ttttgtccgt gtaacgaaga
     1081 aatagccgtc acgatttagt ttgtctaaca acttgtaatc aaagtagccg cgatccacca
     1141 catacgttgc ttgcgtttta tcaacaagaa cttcaaggtg attacggtca tgctcactcg
     1201 catttgtcat cgtaaaactt tcaggatact gattggtttt atcaagataa cagagattca
     1261 aatgtagctt gatgccagac tttgttttcc gaaacttggc ccatggaaac catgctttgt
     1321 tcaacggaat agtcgttgaa tcaatcaatt gtagactggt tgtttttgag cttggctgct
     1381 gagcagaaat tctggcgact aattgcgtaa aaatttccat caatacttct tgcttgattt
     1441 ctggcgctct acgagataac gagctgtaac acagggaatc aatgccaagt tccttgcaga
     1501 ggcgctgatc taaaaaggcg cgatcaatct cgcgatagct tggcaattct tcataaaccg
     1561 catgaagtaa cactttaagc gtcgtttgga agtctagttt tttactgtag aaatcaaagt
     1621 cgctaattaa gctttgagag ttttctgata aaccagaaaa atttattgca gaaaaccatt
     1681 tttgaaatga ggtttttacg ttatacttat ccatgcgtga gtccttttta ttggtcttgg
     1741 ataagtcatc cgagaatagt ataaaggact tttttgcgtt tggatagctt tgtattaggc
     1801 ttttgatggg ttaaaaagtc tttgcaacac tagtaattta gtatttatgt ataaattgaa
     1861 agatatttta ccaccactta gtcttcttaa aagtgatcca acattttgtt tgtggcagaa
     1921 tttaactaca cactaatgca gccgaaagta cacaactatg cagcagtttg actgcgaact
     1981 ggtttccttc catcataagt ttgaatgact tagtgatgga ggtacagaaa ggttgttaac
     2041 tttggatgat attaaaacaa taaaacattt gagaaataat cgtgatcagt caattgatca
     2101 gataagaaaa gcaatgaata tcaattggcg aacagcgaaa aaatacgccg atagtgatca
     2161 actattcatt acagatccca ctcgaaaaaa caaatccatg atggatgatg gttggggaga
     2221 aatcatcggt agttggctag aagaagacct acgtttacgc agaaaacttc gtagaacggc
     2281 caaagctatc catgaacaat tgaaaccttt gggtttccct ggctcctatc gaacagtttg
     2341 tgtatacatt tctcaatgga aaaagcagcg ttacgacgaa acgaattacc aagctgtcga
     2401 tcgtcttgat catccgatcg gagaagcaca ggtcgatttt ggaacaatgg aagttatgca
     2461 tgaagatcac atgaaagata tacaacttct tatcatgtca tttccctata gtaatgcgac
     2521 gtccgcaagt gccatgccag ctcaaaacca agagtgtttc ctggaagcat taaaacaact
     2581 atttaatcaa tgcggcggcg ttccaaaaac gatcagaata gataacttaa ctccagcggt
     2641 gaaaaaaaca aaatcaaaat ttgaagaagc acaactaacc gatgaattct tacgtttcac
     2701 cattcattat ggttgtgatg ttcaagtctg taacccacgt agtgggcatg aaaaaggaca
     2761 tgtcgaaaat aaagtgggtt atgtccgata caatttcttc tcgacttcgc caatcatgga
     2821 ctcttttgag tccctaaata agcaacttga agaacaatta aaagcagatc gaaaaaggac
     2881 gcattattca aaacatcaat taatcgaaga tttgtggaag aaagaaaata aagcgttaca
     2941 ttctcttcca caagaggatt acccaatttt taaagaagtg gaagctaaac taaatcgtta
     3001 tcacgaaatg aaattggatc aaacggttat tcatattcct aaagcatatg gctattctca
     3061 attgactgtt gttttgactt ggaataaatt caaagttctt acgcctcatg gagaaatatt
     3121 aatgaacgaa tatcgcccct atatgaacaa aaaaagattg atcccatgga gtgacatcat
     3181 gaaacaatgg agtaataaat tgaatgtcgt tagttattcg aggtattgga agtacttgcc
     3241 tgcacgcctt caaaattatc tagcgattga taataatcac ctgaaataca gacggataaa
     3301 acaattacta agtttattag cgacctacga tatccaacaa attaatgaac aattttacga
     3361 attagtcgtt caagaagacg ccccctctga ctttgatgtg aattggtcaa actatgatgc
     3421 attaacaaaa acaggaggtg tgcaaaaatg attggacaga cgttagaaga ttattgtaaa
     3481 aagcttcgat taagccatat catcacgaac ataccaagag cttctttcga agctccagaa
     3541 caatttatta ccgatttatt ccgtttagaa ctggagacca gacagcagat caaattagaa
     3601 cggatggaaa aattagccaa atttcctgta ccaaaatcgc taaagaacta tgaatggcac
     3661 gaagatattt ttctaccatc tcatctagat aaggagaccc ttgtctctct tgattttcta
     3721 aaaaggcaag aaaacattgt ttgtgttggc tctcctggta cagggaaaac acatctagcg
     3781 atcgcattag ggagaaaagc ctgtagtgaa ggtgtttcaa ccaaattttt ccgagttaac
     3841 aatctcgtag agcaattaga gaatgcatta aaaaaacaac agctagccag tttcaagaag
     3901 cgattcgaaa caacagaatt aattattctt gatgaaatgg ggtacttacc attgacaaaa
     3961 gaaggagctg aacttctctt ccaactgatt tcagattggt atgagcaaaa gagcattatt
     4021 attacctcta atttagaatt cagtcaatgg aatcgagtgt ttatggattc tcgattaaca
     4081 gctgctctcg ttgatcggct aatccatcac gctcacatta tcagcttcaa aggcgaaagt
     4141 ttcagattga aaaattcatt atctaaatca tattgaagga aaaaactagt tgcagcaaaa
     4201 ctctgcactt tcggctgcat ttttttgtaa aaagctattg cacaacacaa acatttgaac
     4261 gacgtaattc caaatgttgg attgctttta gataatcttt tatttattca caattgctaa
     4321 tagtccaatt ttcatttttg tatagtttta atctatactg aaaaacactt gttgttttgg
     4381 acaactcatc aagatactca acaccaacaa tcacttgaat cgctttaccc ttttgtttgt
     4441 aaataggatt cactaattcc acaaatttca aattagtatt aattggttgc atcgcgtctt
     4501 tttcaacata atgctctagt tctttttctg aggctgctgg ataaagcctg aaaaacgtct
     4561 ctaaaaactc ggtgatttct tccgttgtct ttgaatcaat ttttgaatca ctttttactt
     4621 gtcttacttt atgttttgcc ttttctggct taccaatcat agtgggtaaa ctcgttacaa
     4681 tatgattgcc tttttcatct tcaaagatca tcagacgata tgcagaagaa attgattgtg
     4741 tctttttccc ttctgtaatc ttttgatcta ccacaaatga aacgacaaat tcttccgagt
     4801 gtttttcaac atctagaatt tttactgata caacctcgga actagtggga atatccgctc
     4861 gaaccatatc ttggctcaaa gcgagccctt cttctgtaag gtactgctca agattagtca
     4921 ttctcttttc aattacctcc ttgttattct tccatgaaaa atattctttc acaaaatcta
     4981 cagtaaaatt ttctactcca gaggtattca ctattttctc tttcacgacc actttctcat
     5041 gagttgtatg ctgatcaatg gccgtgaagt ttttgtagat tccaaaagca aggctacaag
     5101 acaataaaag ccaaagggca agcaccattt ttcgatgctt gcccacggat actactcgtt
     5161 ctttcttctt ttttggaatc ttttccttgt tacttcgctc aatttttatc ttcattttcc
     5221 attcctcttt tctattgttt ataccgacca gcaccaataa tgtgctgttg ccaatagcta
     5281 tcggtaagat tggtccaacc caccggatct cctgcatgaa acattctgtt ctctcctgca
     5341 taaatgccca catgagtcac ataagtaccg gcatcataag ttgaatgaaa gaaaatcaaa
     5401 tcgcctggtt tggcatcttt taagtcaata tgagtcatag catcatattg atcctgagcc
     5461 acccgaggga gtttcaaacc aactttggca taacaccatt gagttaaacc actacaatca
     5521 aacccagttc cgggacttga cccaccaaat acataagccg ttccttcata cttgaacgcc
     5581 tcgtcaaaaa ttccttggac tgttttatca tcaaactgtg ttgtagttag gtactgcttc
     5641 actaataagc aataaaacat attgccatag ttataccgcc acccactatt ttccttaatc
     5701 gcgatgggat tgggataatc gactttttga ccacccgatt tttcttttga aaaagattcg
     5761 gctaaagcaa aactatgctt ctttccgttt ttcgcgacat aatccaaata cccgtcacca
     5821 tagttataag cctgaatgat actatcttga tcgcatccta gttctttgga acacttaacc
     5881 aaagacgaaa aatagagaca cacttgtttg atggatgcct cggtacttaa tgaattcggt
     5941 gataaacctg ctgattcaga actttgcatg acatcttcca ttgtacctcc agattcgact
     6001 tgaataatcg ccaaaagaat cgaaacatac tctgttatat ctgattcttt ggcatacttt
     6061 tccaccattg aacggtgttt caaaactact tctgagacac tactacctcc aggagaagtt
     6121 ccagaactac cacttccctc accgtcctca ccaaacaaca aacccacaca catcaagatg
     6181 cccacaaaag agatggtcag gaaggttaac gaaataatac tcaatttttt taagttcatc
     6241 ttttctcacc tggctttggt tttgggcgag tgttcttttt tctttgtact tgttgattgg
     6301 ttcgctttgg aaaagtgaat ctctgtttca cttgttgaaa ggaattgttc ttgcttagtg
     6361 gctgagtgct tccgtttgga atgacttctt gactagaaag tttccgtttg atttcaggat
     6421 tcgaatgtac ttgtaccctt ggttttaaag acctattttc tggtagttca tttttctgtg
     6481 gttttatctc cttttttatc ggaacatttt cccttccttt ctcatgacga ttccatgctt
     6541 cgttcaatac tttgcgtttt tcatccattt ttgcgtctct tcgttgtcgt tgtttttctc
     6601 gcaactcccc tcgatttgct ttttcttcga aaggccctcg cttaaagtcc tctggtactt
     6661 ttttcgtctt ttccatgcct ttatgaaggc tgtatttcaa gttagttggt gcatcggtta
     6721 cttgattttt tgcttgtttc gctttgtcct tcacgatttc ttttgtatcg agtacttttc
     6781 caacttttct accaactaaa tttattcgtg attctttctt cgtgcccact ggttgttctt
     6841 gttttttcag atcagaattt agctcgttaa tgcttctcgc ggaatggttc tttctattgg
     6901 acactctatt gatttttgaa ctacctttcc cttttgtaga actggtagct agtttcccac
     6961 caactgctgc accgccacca aaagcaaaag ttcgacccac atttcgatta agctgtcgca
     7021 attttcgatt catcaacatt tgcggtttcc gcatgactcg ccttcccatt gactgactat
     7081 cattactttg aaggttaaac atgctcataa tgtcacctaa tttgaaatag ataccggcaa
     7141 aggtcacaat ttgtagaaaa gctaccataa agaagggata ggtggccgaa atattgaaaa
     7201 acatcgtgga gatactgaat gcagtcgtaa tgactaaggt aactcccgct cgcatcataa
     7261 tcgtattgaa caaacgaata atcgcccttt tgcccaaact ctcatacgtc ggcaacatcg
     7321 acaataagaa actaatgggc agaaacatcg caaagataat gaaaaggatt tgtgagaaca
     7381 acataatccc tgtcagaaga aacacaaaaa aggaaatccc aatattaaac aacactaaaa
     7441 agaccacggt tcctaaacgg ttcatggtct tggtaatact gagattcgca ttgtcattat
     7501 cttcaatctc tgctttgact gcttcttccc gatccttacc cttattttca tccggactca
     7561 cggataaaat cttattaacc cgaccctcgc caatttcttc tatattggaa tcatcgaatt
     7621 gtaatagtaa ccagggttgt tgaacttgaa tcgaaaataa actgtctcga atcaaatcca
     7681 cactatcttt tccctggctt tctgaattag gtacaacaat cttggttcca aggctaagag
     7741 ccgcttcact aacgtctgag ctaaagtcat tgatttttgt aatataggtg ggcgcatacg
     7801 caatgaaaga acccgagagt agaaaaatca tcacaaaatt aatgacggtt cggactgctt
     7861 tggtagtttc tcgttttaat aatccggtat acgccacata aactcctaga gctaaaatca
     7921 tcaataatag gaacccaaag tagaatcccg aagtctgtaa tccattttca gtgataccgg
     7981 ctaaagtttg gatattcttt ccaatacttt tagccgtatc cgaaatgaaa tccaacttgt
     8041 aagcttcttg aaccacatag cccgtggcgt ttgataaata cagacttact gtccaaataa
     8101 aattggtaat ggcataaaga ccatacatca cgcttttccc taagccatcc ccccaattcc
     8161 aaggtaacca atcccaagaa ctatccacaa agaaatccag ttgataattg ttcagagaat
     8221 atttggaata aaggtttccg gcttcaactg tatcatcaac cagacctgtc gcctcagcta
     8281 ccgtaccgac taaactcaat agaactgtca gagtgacgat gctaataaaa acgattccca
     8341 caatccgaaa aagtttcttt ttcatcccct cactccattc tctcttgaac cggcggacga
     8401 gtgtcaaaag catggaagag ttcttcaaag actggatgaa cttgaaccac acctactcgc
     8461 ccatacaagt cttgcatcaa gcattgaccg ttt
//
LOCUS       DADQDV010000096         8424 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.099, whole genome shotgun sequence.
ACCESSION   DADQDV010000096 DADQDV010000000
VERSION     DADQDV010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.099"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            471..2108
                     /locus_tag="J8S10_002642"
     CDS             471..2108
                     /locus_tag="J8S10_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HAZ9631204.1"
                     /translation="MKKNKNQIIDIIFMLFLSFAYVIPLFMSMGIYHSVNQDTYFHLS
                     RIIGLDNVWSSPVNFNNFDHHGTMMNIFYPWLTLYPAFLFYKMMGNLVLSYNIYYFFI
                     TFLTMVVSYFSMKQIKNNRYISLLFSIIYTFSAYRAIDIFHRASLGEAVALTFLPLIL
                     MGCYEIYIRDYQKWYWLSIGMTLVVYTHLLSVAMVSVFIGGTLFLSFYFWDQKIARLL
                     SLLKATVLTFFLSAGFLIPFIQQSRAQELKVPLGKELSGMAPSDMLTHILNNNYNNYT
                     IGLFLFLGLIGAFIFIKKLTADDLFIFFLGVFVLFCSTNLFPWQLFNHTPVKSLQFVW
                     RLNGFSSLFIAYTMSIVIYYIFSTKNNSWKIMVFTFLALILHLSGVSNSIHANKDSLT
                     LIAPEDAVAIAENYNHTDYANKESIYHPDMINNDQYLLGNQEINPTTHFMSNKLTIEL
                     DNSNNKNTVLTTPIYRYKGQVASINGKLVQTKLSKFGTTELTIPPGINKVVITYQYTK
                     LAIASRYLSIVTLILFLLYRFTFSKQKQPRREVQHSH"
     gene            complement(2253..2993)
                     /gene="truA"
                     /locus_tag="J8S10_002643"
     CDS             complement(2253..2993)
                     /gene="truA"
                     /locus_tag="J8S10_002643"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HAZ9631205.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(3184..3819)
                     /locus_tag="J8S10_002644"
     CDS             complement(3184..3819)
                     /locus_tag="J8S10_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HAZ9631206.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            complement(3966..5207)
                     /gene="sstT"
                     /locus_tag="J8S10_002645"
     CDS             complement(3966..5207)
                     /gene="sstT"
                     /locus_tag="J8S10_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HAZ9631207.1"
                     /translation="MLEKFLDMSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSC
                     LKAIAPILVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPIT
                     LQETVSEKAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEST
                     KELVDQISIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLF
                     VALVVYPFLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKE
                     SYSISIPLGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGV
                     AGGSLLLIPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELG
                     ARKRSGEKIKLKDCLDGLSER"
     gene            5405..6401
                     /locus_tag="J8S10_002646"
                     /pseudo
     CDS             5405..6401
                     /locus_tag="J8S10_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302657.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            6417..>8424
                     /locus_tag="J8S10_002647"
     CDS             6417..>8424
                     /locus_tag="J8S10_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAZ9631208.1"
                     /translation="MSLLVIFLFYIQKIRFIHRFIEYFAFDSIEQLTQRWKKRIHWLF
                     VHKSYFLVAAFFYCFTFVQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFF
                     FLLLLISNRFWYALTATLIINLLLTISTVIKMEMREEPVFPSDLKILTGLSELLSMVS
                     PVLLIVGGLILLLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHK
                     NSPSFLLFNLFKVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMK
                     KYNTKADEINQTRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTG
                     GLMLSVGYGGGTANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIA
                     IHPFTAALYRRKQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQ
                     SNTETSQFIQLSTMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAV
                     KKFIQEIDKIDKPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAAT
                     LNKEVVAPNNFGAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVF
                     VTEDSQIIQEKNLTEKQKEILEDYRLIQYDLVAGNQYSATWATQK"
BASE COUNT         2785 a         1547 c         1293 g         2799 t
ORIGIN      
        1 aactaatcag aatcgtacaa atatttaata accaaatata tagaacataa cttaatatta
       61 agttatttga aattccataa aaaacgactg caggaattat tgtaagaaaa ggataaaaat
      121 agttcagtcc atctccataa ttgttaaatg ttgtatagtt gattggccct tcaaaaatag
      181 aagataaccc tttgattcgt gaaagatgaa aagataaatc acctgttgta taaatttctt
      241 gagcatttct cataaaattt actgaatata aagtactaag taagataaga actactaaaa
      301 gaaatgcttt tttacttatt ttcatagatt tgttgttctc cttttttaat tctattttca
      361 gtatactaga attgtctttt tttaataagt tttgcgttaa atttttcata gcactagtat
      421 gatatactag aaaagaatca atttttatta cttttaaata ggagaaaaaa atgaaaaaaa
      481 acaaaaacca aataatagat atcattttta tgttatttct aagttttgct tacgtcatcc
      541 ctctattcat gtctatggga atctatcata gtgtcaatca ggatacttac tttcatttat
      601 ctcgaatcat aggactagat aatgtatgga gttctccagt aaacttcaat aacttcgatc
      661 atcatggaac aatgatgaat attttttatc catggcttac tctttatcca gcttttttat
      721 tttataaaat gatgggaaat cttgttttaa gttataatat ctactatttt tttatcactt
      781 ttttaacaat ggtcgtttct tatttttcta tgaaacaaat aaaaaacaat cgttatattt
      841 cgctgttatt ttcgattatt tatacatttt ccgcctatcg tgccattgac atattccatc
      901 gtgcttcatt gggagaagct gtcgctttaa catttttgcc tttgatacta atggggtgtt
      961 acgaaattta tattagagat taccaaaaat ggtactggtt gtctattggc atgacgctag
     1021 tagtgtatac tcatttactt tctgtcgcta tggtttctgt atttattgga ggaacgttgt
     1081 ttctttcttt ttatttttgg gaccaaaaaa tcgctagact cttaagtctt ttaaaagcta
     1141 ccgtcctcac ctttttttta agtgcgggat tcttaattcc ttttattcaa caatctagag
     1201 cacaagaatt gaaagtccca ctgggaaaag aattaagtgg tatggctcct agtgatatgc
     1261 tgacacacat tttaaataat aactataaca actatactat tggattattc ttatttctcg
     1321 gattgattgg tgcttttatt tttataaaaa aattaactgc tgatgattta tttattttct
     1381 ttcttggtgt atttgttctt ttttgttcaa ccaatttatt tccttggcaa ctttttaacc
     1441 atacaccagt taagagtcta caatttgtct ggcggttaaa tggtttttct tctttattta
     1501 tagcctatac gatgagtata gtgatctatt atattttttc tactaaaaat aattcatgga
     1561 aaataatggt ctttacgttt cttgcactaa tattgcatct ctcaggagta agcaattcta
     1621 tccatgctaa caaagattca ttaacactta tagcacctga agacgctgtt gctatagctg
     1681 aaaattacaa tcatactgat tatgcaaaca aagagtcaat ctatcatcct gatatgatta
     1741 ataatgatca atatttacta ggtaaccagg aaataaatcc aacaactcat tttatgagta
     1801 acaaacttac aattgaatta gataattcga ataataaaaa tactgtcttg acgacaccta
     1861 tttatcgtta taaagggcaa gtggcttcta ttaatggcaa actagtacaa acaaaattat
     1921 ctaagtttgg cacaactgaa ttaactattc ctccaggtat aaataaagtc gttattactt
     1981 atcagtacac aaaactagca attgcttcaa gatatttatc tatcgttact ttgattttat
     2041 ttttacttta tcgatttact ttttctaaac aaaaacaacc gagaagagaa gtacaacatt
     2101 ctcactagat ttttatttaa gaaagacttt ttagctgtac acataaacag gctaaaaagt
     2161 ctttttttat atttctttaa tttgcttcat acattattta acatcgatat ttatactgtg
     2221 aaacatgcgt ttcatccatt atcaaagtat ttttatcgat aataaacttc atccaaaaac
     2281 agaccttgtg cagggacggt ttctcctgca tgttgccgca ctttgctttc aaatatttca
     2341 tcgattgttt ctatcggcat ggcacctgtg ccgatttcta gtaatgtccc catgataatc
     2401 cgcaccattt tatataagaa tccgtctccg acaaaagtaa aatgaagcat ttctcccttt
     2461 cgttcgatag ataattcatc aatcgtacgc actgtggatt tttttgattt tttcaatgca
     2521 gaaaaaccaa tgaaatcatg tgtacccact aatttttcgc aagctgcatt cagcttgtcc
     2581 atatccaact cttgagggaa ataaaagctg tggtttcgct caaatgctga aggaatcacg
     2641 ttgttccaaa cataatagct gtattttttg cccaccgcat tatatcttga atggaagcgc
     2701 tcaggcattt cttcgattct tttgatgaca atatcccgcg gaaggtaacg attcataaag
     2761 tcgatcattt ctgccagtcc aatttctgtg tttgttttaa aatttgctac ttgtcctcgc
     2821 gcatgggtgc cagcatctgt tcttcctgat ccaataattt ctatctcttc atttgtcatc
     2881 tgatgcaata ctttttcgat ttttccttga atggttttat cgtcatctcc aagtctttgc
     2941 catcctgaat atctttttcc gtcatattcg attgtcaact tgatgtttct catattttag
     3001 tggctcctct gtcttccatt tggtcttctc tctacctttt taagattgta gcacaaaata
     3061 tagctccttt cttctctaaa acagaagcta tacaagaaaa ctgtggaaat atatatttca
     3121 gaaaaacaaa aaacagccac cggatgaagt atccgctgac tgttcaattt gacggctcaa
     3181 gttttactgt ttgagatgca agatactcaa ccaggcaatg ggcacataat taaagaaaaa
     3241 actgattctt tggcaaaaac ctattttatt cagtaatggc caagaattta tagaaggaat
     3301 tcttgccagt ccataaatcg ccgcaaaaag caaactgatc acagacagtc caaggtataa
     3361 gtggcttacg tccatttgcc cattttttcg atagatcaag aaaagaagaa ctggaaacaa
     3421 taaaaaacca ctgtaaccta aacctgatcc gatattatgg acccatgtcg agacattcca
     3481 cgaagattca tgggtattga tactgaacaa acctgtaaag atacaatcac ctataccata
     3541 gaacgcgatg gctgctgtaa ctagggtagc taacacacga gatgtactta caaatgcagc
     3601 atacaatgca ggcaatgaca ggatgaaaaa gatccctgaa accacagacc aaataagaaa
     3661 cgcttttctt acaggactgg aaacctctcc aaatacactg atcacgctct tcatttgatc
     3721 taattcagga taatacaatc ctaatacgta cggagtcaaa aaatcactca gcacgcctaa
     3781 taataaaaag aaaaaaccaa atttacgtaa aaaatccatg atacgcctcc aataacaatt
     3841 acctatgctt ttaattgtta ttataagcga ctttatcttg atttaacaga aacctctatt
     3901 tacacgaaca tctatataac tcattaaaaa ctcgaatcat tttaaaaata ctaaatatct
     3961 aacgttcaac gttcacttaa tccatctaaa caatctttca atttgatttt ttccccactt
     4021 cttttacgcg cgcctagctc tcctattgca gtaaacaaca gatcacttga cgaatttaag
     4081 gcagtttcca ttgaatcctg gataacaccg ataataaatc caataccgac gatttgcatc
     4141 gcgacatcat tagagatacc aaacaaacta catgctaatg gaatcaataa cagtgaaccg
     4201 cccgcaacac ctgaagctcc acaagcagct aaagcagaca aaatacataa aaggactttc
     4261 aaaacaaaag gtgcttcaat ccctaaagaa tgtacagcag tcaacgtcat caaggaaatg
     4321 gtaatcgcgg caccgcccat attgatcgta gcacctaacg ggatcgatat ggaataagac
     4381 tcttttgtca atttcaatct ttcagccaac atcatgttta tcgggatatt tgcggcagaa
     4441 cttcgggtaa agaaagcggg aagtgcgctt tctttcaaac aaaagaaaat caatggatag
     4501 ggattttctt taataaacaa aaacgtgagg aatgggtaca caactaatgc gacaaacagc
     4561 atcgtaccga tcaaaacaag taaaagctgc agatactctg ccaatccagc tattccagtc
     4621 gtagcaattg attgataaac caatcctaaa atccctatcg gagcaaatgc aataatcact
     4681 tgtacgactt gtgacaacgc tatagatatc tgatccacca actcttttgt cgattctgaa
     4741 cgtgctcgaa aagctagtcc caacaataca gcccagaata agacgccaag gtaattcgca
     4801 tcaataagag attgaacagg attttgtgtg acattcgtca acatagtaga taaaacactt
     4861 tccaaacttt gcggtgcttt ttcagatact gtttcttgta aagtaatagg aacagtaaaa
     4921 attgaactta caataactgc tacaagtgca gaaagcaatg ttcccactaa atataagatc
     4981 aaaataggct tcacgaatgt cttattccca attttatgct tggcaattga cgccatcgtc
     5041 aagaaaaaaa ccagaatagg tgcgattgcc ttcaagcaac tgacaaacaa cgttcccaat
     5101 attgaaataa atgtccatgt ggggaaaaag ataccaaaca atattccgac taaaatacca
     5161 acaacaatac gttgaactaa cgacatatcc aaaaacttct ctaacaaatg accacccttt
     5221 cacaatttta acaatcattg tatcatttta tgcaaagaaa ctaaaggtat aattttctaa
     5281 aaattctaac aatacaaaca accatttctt gctaattttg tactttttct gtctacacgt
     5341 tgttttttga gatattctaa gttaggatgt tattaatggg caacttatca ggaaacgttt
     5401 tcttatgttt ttgtccaatt tttttgtgag gtgtttattc ttgaaaaaaa taaagaagga
     5461 gagttatggc ttcctgacaa tctttgtcgc ttgtataatg atggttttac agcgtatatt
     5521 gatttcagca gtcactattc ctacatatgc aacaaaccct ggtcgattct acatctatac
     5581 atttttacaa acttccgttg ttattggtgc aaatttgatc ccactttaca tgggttacca
     5641 atatcaaaaa atcgcccgtt taaaagtttt acattattta agtcgttttg cctttatatt
     5701 cctaatagcc acactagttt gcaatatctt ttttttacgt acaagctggc agcttgaata
     5761 ttcgtgatta ttggcttatc ctaacaccta tcagtcagaa ttactttact tatgctgttt
     5821 cttgtacttt gcttttttgt agtattcctt atacagttgg atttttaaat aaattatcga
     5881 aaacaacaat taaatatcta ctattatttt taacaattgg attagttggc tgctctactc
     5941 tatttaataa agacccgttt gcattacaga atggacagag tattttatgg attttttatt
     6001 tatttttaat gggttatggt ttgaaagaat ggaactggaa agaaaaggtc cgctataagc
     6061 ttcctcaagt atttatcagc ttgattgttt tattcggttt gattattttg atgacacaaa
     6121 tttcactcat catcagagga aatacagata cagcgctgag gttttctaaa ccatattctc
     6181 tcttcgcaat gtattatact ttctcttcgt ttttattttt agaaatgcta tctgataaat
     6241 taggtataaa aggaagagga aattttcttg ctgtattttt gattgtcact caagttatat
     6301 gtaatttccc tttagtttct tatcgcgtat ctacatttat gaaacgtgaa tttccaaact
     6361 cagggaaggc atggctgata aatatcgggc agttttttat ttgctattta ttagcagtgt
     6421 ccctcctagt tatcttttta ttttatatac aaaaaatccg tttcattcat cgtttcatcg
     6481 aatacttcgc ttttgattcg attgaacaat taactcagcg ttggaaaaaa agaattcatt
     6541 ggctttttgt tcataaaagt tattttttag ttgcagcatt tttttactgc tttaccttcg
     6601 tgcagatttt cgttttagaa ccaaaagaag gttggaaaga aactatccag gttgccttaa
     6661 aaatatttac tcagcgacaa gcacccatga tcctgacaat catcattatt atgggatttt
     6721 tcttcttact attgttgatt tccaatcgtt tttggtacgc cttgactgct accttgatca
     6781 ttaacttact gctcactatt tcgacagtaa tcaaaatgga aatgcgggaa gagcctgtct
     6841 ttccttcaga tttaaaaata ctgaccggat tgtcagaact attatcgatg gttagcccag
     6901 tcttattaat cgtgggcgga ttgatccttc tcctattatt gattactagt attattgtac
     6961 aacgtagact acaaaaacag tattccttga agattcattg gaaacgtcga tttatcagta
     7021 tcgctgtatt attaggatgt ttttcgggtg tctttttcat taatcacaaa aattcgcctt
     7081 ctttcttgct gtttaattta tttaaagtaa acaagacttt ctttaaccag caaggcgccg
     7141 taaaagataa cggaccagtc attcaattcc taaacaatat cgacattaaa atcatggaag
     7201 aacctgctgg ctattcgaaa gaaaaaatta atggaataat gaaaaagtac aacacaaagg
     7261 cagatgaaat caaccaaaca agaagtgact ggttaaacaa tcagacgatc gttctcaatt
     7321 taagtgaaag cttcagtgat cctgcacgtg tccctaatct gacagtacct acagacccta
     7381 ttccttacat caaaagcatt ataacagaag gaacaggagg attgatgtta tccgtcggtt
     7441 atggtggcgg aacagctaac atggaatggg aaggactgac aggcttgagt atcagtaacc
     7501 tgtctgcttc gttagttaca ccttataccc agctagtgga gcgtcagaaa ataagtccaa
     7561 atattaccga tctattcgat gaaaaaatag ccatccatcc ttttacagct gctctttatc
     7621 gcagaaaaca agtgtttgat aaatttggtt ttgacaggtt ctattattta gacagtccgg
     7681 ataaattaac ttatacggat aaaatagaac aaagcccacg catatcggat gattcagcat
     7741 acaaagaaac cttgaaagct ttacaaagca atacagaaac gtcacaattc atccaattat
     7801 ccactatgca aaaccatatg ccttatgatg attactatag tgaattgaac tacactgctg
     7861 aaggaactgc tgtcattcct aatagaagaa aagaattaca aacttatatg caaggccttc
     7921 actataccga tacagcagta aaaaaattca tccaagaaat cgacaaaatc gataaaccga
     7981 ttacctttgt tttttatggt gaccatttac ccgcaatcta tagtgggaat gattcgaaaa
     8041 aatatggatt agaacagcac cagacagatt atttcattta taacaacaag tatagtcgtg
     8101 aacaagcagc tacgttaaat aaagaagttg ttgctcctaa taactttggt gctatggctc
     8161 ttgagcatgc gaatatcaaa gtaactcctt actatgcgtt gttgacagaa gtatctaatc
     8221 atctacctgc attaacaatt gatcctacag aaagcttgtc taatcgtttt aatggaaaac
     8281 aggtctttgt tacagaggat agtcaaatta tccaagaaaa aaatttaact gagaaacaaa
     8341 aagaaattct agaagattat cgtctgatac aatatgatct tgttgcaggt aaccagtaca
     8401 gtgcaacatg ggcgacacaa aaaa
//
LOCUS       DADQDV010000097         8322 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.100, whole genome shotgun sequence.
ACCESSION   DADQDV010000097 DADQDV010000000
VERSION     DADQDV010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8322)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8322)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8322
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.100"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            306..1631
                     /locus_tag="J8S10_002648"
     CDS             306..1631
                     /locus_tag="J8S10_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HAZ9631209.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPAAKKKYGISNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSMNLFTTEGTRSQRRKKLAQMIQENIKEELGLLA
                     TVGVGDNPLLAKLALDNEAKHNDGFLAEWTYQNVPDKVWNIPEMTDLWGIGSRMKKRL
                     NQIGIMSIKDLANWNPYTIKSHLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLYIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGAGGLKND"
     gene            1624..1974
                     /locus_tag="J8S10_002649"
     CDS             1624..1974
                     /locus_tag="J8S10_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631210.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEKIDADNEQRANQNLAKEQMTTE
                     EVAEVLNAAVIKNRSVCIQKEERNAEGYYPEDIVSKILGSDELGIYVGKNKVHYDEIR
                     HIEFYQDNKWGRLE"
     gene            complement(3045..3320)
                     /locus_tag="J8S10_002650"
     CDS             complement(3045..3320)
                     /locus_tag="J8S10_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgO"
                     /protein_id="HAZ9631211.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVD
                     PPVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
     gene            complement(3292..4245)
                     /locus_tag="J8S10_002651"
     CDS             complement(3292..4245)
                     /locus_tag="J8S10_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAZ9631212.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLF
                     EKDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGS
                     PGSEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAAD
                     YIIAMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQ
                     KTIDKYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYY
                     EQHGDIEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
     gene            4857..6350
                     /locus_tag="J8S10_002652"
     CDS             4857..6350
                     /locus_tag="J8S10_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein RepR"
                     /protein_id="HAZ9631213.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSK
                     QLMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINT
                     FVVDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVI
                     DVAKKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSM
                     KLESDQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTL
                     SLAYYSSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELC
                     QQWVSPTLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLN
                     LSKKELASQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLS
                     KEKRLDYSTRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
     gene            6485..6781
                     /locus_tag="J8S10_002653"
     CDS             6485..6781
                     /locus_tag="J8S10_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HAZ9631214.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTR
                     EKTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
     gene            6882..7733
                     /locus_tag="J8S10_002654"
     CDS             6882..7733
                     /locus_tag="J8S10_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631215.1"
                     /translation="MKSDDWIEHTWLPLKRNSKRKKFWVLQLWPLGKLCSYGARLILD
                     LTVYSIGVFGTAYYLINDPNRIAASDIFTVLMTLIFVMLLSIFTQLVMQFTRQKLTAG
                     KLFKSLFDLIVVNAILATLIKQIEQSGRTTKGVKDFLLTFIHFVNGHMYLFEVGIILF
                     FVGYVSTKLIKRSIEKEIEIDLIPTLLGYEYNVDFGRYDELINTDIVHTSIHESTVKG
                     IRSILKNGQEMKAIDRRKEIYNFYEVEASLRYGIGKLWLDGSNIRQNKPYIFWNSSDL
                     ELPMKDK"
     gene            7754..7966
                     /locus_tag="J8S10_002655"
     CDS             7754..7966
                     /locus_tag="J8S10_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631216.1"
                     /translation="MIPLYRIVLIVGMELKTLKKEQLFKVKERHNQLLCSKTGTMNIE
                     YRTEYLELTNQTDFLLIRKQQEQEKN"
BASE COUNT         2886 a         1290 c         1560 g         2586 t
ORIGIN      
        1 caaaactatt aagaaactga atactcctat tttttgtttt taaggaaagt tttttctttt
       61 ttgaatttct tatttttttc taatataact aagcaaaact ggataatacg acacttattt
      121 tcaaattttc acaagactaa tagtaaatat ccatttaata aagtgataca atgtgttgat
      181 tttacaaatc aacagaagaa gtagggaaat aacttaccta tgcttctttt tttgtacatt
      241 taatcgattc ttctttacaa aaacgaacgt atgtttgtat aatgtggaag aatggagtgt
      301 tatttatgat ggattattca aaagagccag taaatgatta ctttttgatc gatatgaaaa
      361 gcttttacgc aagtgtcgaa tgtatagaaa ggaatttaga tccattaacg actgaattag
      421 tcgtcatgag tcgagcggat aatacaggat cagggttgat tttagcttct tcaccagctg
      481 caaagaagaa gtacggtatt tctaatgtca gtcgaccacg agatctaccg caaccttttc
      541 ctaaaacgtt acatgtcgtt ccaccacgca tgaatctcta tattaagcga aatatgcagg
      601 taaacaatat tttcagaagg tatgtagcag acgaagattt attgatttac tcgatcgatg
      661 aatcgatctt aaaagtgacc agatcaatga atctttttac gactgaagga acaagaagtc
      721 aacggagaaa gaagctggct caaatgatcc aggagaatat taaagaagag ctaggattgc
      781 ttgctacagt aggtgtcgga gataatccct tattagctaa acttgcttta gacaatgaag
      841 caaaacataa tgatggattc cttgctgaat ggacgtatca aaatgttcct gataaagtat
      901 ggaatattcc tgaaatgaca gacctttggg gtattggatc tcgaatgaaa aaaagactca
      961 accaaattgg tatcatgagt attaaagact tagctaattg gaatccatac actattaaga
     1021 gccatttagg tgtgattggc ttacagctgt attttcatgc gaacgggatc gatcgaacag
     1081 atatagcgat cccaccagaa ccgacaaagg aaaaatcata tggtaattca caagtgttac
     1141 cacgagatta taccaggaga aatgaaatcg aactggtggt aaaagaaatg gcggaacaag
     1201 tagctattcg tatcaggcaa cataactgta aaacaggttg tgtccattta tacattggca
     1261 cgtcgatctt agaaacgaga ccaggttttt cacaccagat gaagatccct ataacagata
     1321 atacaaagga attgcagaat tactgtcttt tcttgtttga taagtattat gaaggacaag
     1381 aagtaaggca cgttggaata acctatagca agcttgtgta cactgattcg cttcagctgg
     1441 atttatttag tgatccacaa aagcaaattg acgaagaaaa tttagataaa attattgaca
     1501 agattcggca aaaatatggt tttacgtcga ttgtacatgc ttcttctatg ttagaaggcg
     1561 ctcgtagtat tactagaagt acattggttg gtggccatgc aggcggcgca ggagggctta
     1621 aaaatgattg attataatga tcgtggacgt ttaaagtggg caggttttta tttatctgat
     1681 catactgaaa aaattgatgc cgacaatgaa caacgagcca atcaaaattt ggcaaaagaa
     1741 caaatgacga ctgaagaggt tgcggaagta ttgaacgctg cagtcataaa aaatagatca
     1801 gtatgtattc aaaaagaaga acgaaacgct gaaggatact atccagaaga tattgttagc
     1861 aagatcttag gtagtgatga gctggggatc tacgttggaa aaaacaaagt tcactacgac
     1921 gaaatacgtc atatcgaatt ttaccaggat aataaatggg gtcgattaga atgaacatta
     1981 tccagcaata tgagctaaag tatataacct ttgatcagct atcagaagag atttggggtt
     2041 atggccagcg tttgataaat gaggttggtg ttgaacgctt ctctttctat gtagaagctg
     2101 cagcaggata ccataaatac gaatactata ttggctatta aagtgcaata aaattatatt
     2161 tcttttatgt tttacatttt gtatcaattc tgataaaatt acctataggt aattaaaaaa
     2221 tataaaaaaa ctagttacaa ccttaggacg ttgtaactag cttgaagcat actagagcta
     2281 actaaaatag cactagaaag caatgttaaa cccgtccaac aaacttgatt taacattgag
     2341 accagcttat tcagctaaat atagttgaat aagcttcttt tgttttaaaa aaacaaaagg
     2401 tgtactacga ataacgcaag taaaagaaat actattacaa ccagtaggct acaagtaagt
     2461 attactaaac attgcgtagt tagaaccttt gctctattgt ctaaagccac aaaattagag
     2521 atcagcttta tgatgctaag agcgagctgc atccatgcgg acataggttc ttttgacact
     2581 attaattctc ctttttagga taagggaaat tgctagtagt tttttcatta gcaccatccc
     2641 ccttcatttg attgagtcta gtgctgctgt gatagtttgc tgtttaatat gcttacattc
     2701 ttattataac ataaatgaaa caaacacatg gttagaggtc gtatcaatca aaatagtgtc
     2761 tcacaaacga tttattactt actcctgctg actaacggac tgttcttcag taactgtaac
     2821 tatatgtttg ttaaaaccac cattacctgt agataaaaac caatatattt actatactca
     2881 ctatattaaa tatatttagt atagtaaaaa ctagaaacaa taaaatttgt gaatgttgta
     2941 tacccccaaa caatacacat attttgaagg attaggatta ataaagctaa aaatatagta
     3001 agtatactaa atatatttac tatatctagt atacttacta tattttaatc ttttgatcgt
     3061 ctattatata taatccgttc ctcgtcgttt aaagtatcaa cataggcgtc cattgcaagt
     3121 ttgactattt catacatagg aatatctttt gcataactaa gatcccgaat ggtttttagt
     3181 acgggaggat ctacttgaac tggttttctt tctttcgcag tgtactttcg ttcccctaac
     3241 tcgacattaa tatcatcttt aattgaaata tcttcagcac caattttctt cttatctttg
     3301 ttcgttggta ataatgccat ttagtttaat ctcctttcca agaggtagga tatgattggc
     3361 cattgagtca gcatatttag gtgtataatc aaatccttca atatcaccat gttgttcata
     3421 gtattcaatt ctttcttcta attctgtaaa gatgtctgca aaaatagccc accatcttcg
     3481 atctacataa tcatttaatt ggataccatt ctcaccatac atttctaacc gatccgagcc
     3541 tttaacaatg cttttaaaaa tgtttgattc accatactta tcaattgttt tttgatagtt
     3601 tgcgtgttga gaggaacgtc gcactgagaa aagaacaggc aaaattccaa tgatttgaag
     3661 atgagactct tcaaaattcg tgacaatcgg aactaaaact ttattaataa aatcttctgt
     3721 tccttccatt gcgtaccgtt ttaattcttg cattgcaata atataatctg cagcagttaa
     3781 gaatgcacga accacattat ctgttgatgg tgggcagtcg ataaagatat aatcgaaatt
     3841 ttttctcaat tcttctaaag gtttaatgaa ggccaatgat ctcttacgac gatcaggata
     3901 tttttcggac aagtattcat taagttcttc agatccagga gagccagcca taatatataa
     3961 atgtggactt acttgagtaa tacctgaaac ccagtcccct tttttgattg ctgcagacat
     4021 ggatcgatca aagctagtaa tttgatacgt tgatccaatg ttggaagtag tatttctttg
     4081 ttggtcataa tcaattagca acacgtcttt ttcaaaaagt tgactagaaa caatcgctaa
     4141 taaatcattg tctgtagtct taccaatgcc gccttttcta cctgtaagca ttacaacttt
     4201 tcctagttta tctgatgttt taaatgcagt ccgtaagttt tccatagttc cctccaattt
     4261 cctatactaa atatatttag tatacttcat atacttaata tattcgatat atctaatata
     4321 ctccaaattg ataagaattc agactttata aggaatatag tggatatact aaatatattt
     4381 gctatattca gtatatcaga tatattcaaa atgtcaaaat atatttgtgc gttttgcgtt
     4441 gacaatttag agtgaaaaga ggtaaactta attctataga aaccacagat aattcactat
     4501 ttacaaagta gcaaaagcag tggtactctt taaacagaaa aattacataa aaaaaagaga
     4561 cggaaataat tgattttagc agaatcaatt atttctgaat cacatggtta ggacatgtgt
     4621 tcacgctcgt ctcaagaata tgtaagtagc taccaactac ttatattaaa agttgatcgg
     4681 ataccttttc cgattgcctt tattctacca aaaaaaggcg agcaactcaa cagaagaacg
     4741 tttatttagt gtacttaaat taaatattct taaacactga agagagaaca catactatgg
     4801 ctgagattaa agctaaactg tgttctcttt ttgtttgaga aaggacgtta caatcgatgt
     4861 tgagcgaaat ttattcagct attcttaaaa acggcttacg tacatacaaa tatcgaaaca
     4921 gcaccatgaa acctgcaggt catattgatt ccagtaggag tggtgctatc tttgcgtacc
     4981 gtagcaagca attaatgaat gttgggcgtg gtatggtcat tacttcggaa gaagctattt
     5041 tagagaacga aaagaaacta acgcattgga cacctaatac ctatcgcttt ggtacttatg
     5101 cggatgatta tcgaacagtg gttaaaggtc attctgagaa aaacttaagt caaatcaaca
     5161 catttgtagt tgatatcgat tcaaaagaga accatcaagg cgaaattatt ttagcctgtt
     5221 tagatcaagt gggctacatg ccaacgctaa ttttagaatc agatcatggt tatcaagttt
     5281 attttgtact aaagacacca ggctatgtca caaagaaaag caatttcaag gtgatcgatg
     5341 tagcaaaaaa aatttcaaaa acaattcgtc tacagttggc tgaaaaattg tccggagtgg
     5401 atctaggatg taaccacttc ggaattgctc gattcccaca agaaaataat attgttttta
     5461 aagaaatgaa ctatcagtat tcttttgctg actggattca atggtcgatg aagcttgaat
     5521 cagatcaaaa aacaaaagaa gatcgagaac gaaaactaat tgtctttcct gagaaaaaag
     5581 aaattcgtca agtagatgaa ccgtggttcg atatgttact tcataaagca aacatcgtcg
     5641 gcggagaagg acgtcttggt cgaaataatg tgattttcac gctttcttta gcttattact
     5701 cttcaggtta tgcattggat acttgcgaat acaatatgtt cacattcaac gaacggttac
     5761 aggaaccgct atctgaagca gaattagtaa agattgtacg tagtgcttat tctggtaatt
     5821 atcaagcagc aagcagagaa ttcattattg aattgtgcca gcaatgggtt tcaccaacct
     5881 taaaaaataa tgatctgttc attcaacgac gtggctggtg gaaatttaaa aagccacgag
     5941 atcaaagaaa atatagtcat aaaaatgaat ggaaagaaga tctattggct tatctaagcg
     6001 aaaaaagtct tgctagtgag ccttatttga acctgtcaaa aaaagaattg gcttcacaac
     6061 taacgatgcc caagcgaaca cttgataaga tcttaaatga gttacgagag gagaataaag
     6121 tcttctacaa ggtaacacga ggaagaaatg gcggaatgat cattgcttca gtcaaaacgt
     6181 tgttcgcgag ggttattcaa ctaagtaaag aaaagagact agattattca acaaggatca
     6241 cagaggtatt tggactcaac gagagcttag tagaagagac atttagacaa ttatcaaccc
     6301 ccttgaaccc tcttaaagaa gtgaatcttt ttgaagtaga tacaggttga aaaataaaag
     6361 gtgcaaattg ccttatacaa tatatctatg atacttctgt aggtgttgct ccctttgcct
     6421 agctacgtgt aggtggtata cttataactg cgtatgcagt cttatgtatc atggaggaag
     6481 ttgtatgtcg ttaaaaaatt atgtctattc acatcctgtt aatgtgttta tcattggtcg
     6541 tttgggatta tctgtggaag tgttctgtga gctttatggt tttaagcagg ggactttgtc
     6601 ttcttgggtt accagggaaa aaacagttgc ttctttgccg attgagtttc ttcatgggtt
     6661 gtccttagct tctggggaga ctatggatca ggtatatgat tgtttgtgtg tgttagagca
     6721 ggagtatatt gagtataaaa tagctaacga gttaagaaaa aggaagaagt atatccagta
     6781 gtagttttta tttacttaaa aaattggttc attgagcaac ctatcgctgc taaagtagca
     6841 aaggaaaacg ttaaaggaaa gaatttaggg aagaaatcga aatgaaatcg gacgactgga
     6901 ttgaacacac ctggcttcct ctgaaaagaa atagcaaacg aaagaaattt tgggtattgc
     6961 aattatggcc attaggaaaa ctttgtagtt acggggcacg acttattctt gatttaaccg
     7021 tttactcgat tggagtattt ggaacggctt attacttgat aaatgatccc aataggattg
     7081 cagcatcaga catttttaca gtgctaatga cgttgatttt tgtcatgcta ttgtctattt
     7141 ttactcaatt agtcatgcaa tttaccaggc aaaaattaac agcaggaaaa cttttcaaaa
     7201 gcctattcga tttaattgtt gtaaatgcaa ttctagcgac tttaataaaa caaattgaac
     7261 aatctggaag aacaacaaaa ggagtgaagg attttttatt gacgtttatt cactttgtaa
     7321 atggacacat gtatttgttt gaagtgggta ttattctctt ttttgtcggg tatgtatcca
     7381 cgaaacttat taaacgttca attgaaaaag aaattgaaat tgacctgatt ccgacacttc
     7441 ttggttatga gtacaatgtt gattttggaa gatatgacga attgatcaat acggatatcg
     7501 ttcacacgag tatccatgaa tctactgtta agggcatcag atctatttta aaaaatggcc
     7561 aggaaatgaa agcaatagat cgaagaaaag agatctacaa tttttatgaa gtcgaagcaa
     7621 gcctacgata tggcatcgga aaattgtggt tagatggaag taatattcgt caaaacaaac
     7681 catacatttt ttggaacagt agtgatttag aacttccaat gaaagataaa taattatgga
     7741 gaatcgtttg aaaatgattc ctctatacag gattgtgctt atagttggca tggagttaaa
     7801 aaccttaaag aaggagcagt tattcaaagt gaaagaacgt cataatcagt tactatgtag
     7861 taaaacgggt acgatgaaca ttgaataccg aacagaatat ttagaattaa cgaatcaaac
     7921 tgattttttg ttgattcgaa agcaacaaga gcaagaaaaa aattaatggc tacttatagc
     7981 caattgattg atgaatggga acaattcaag gaatctaaaa ttccagaacg tctctaaaag
     8041 cctttatttg taaagagcat aaggaaacgt gggaacactt tttaaaaaaa gtgttccaat
     8101 aggctgtgcc tattacgttt ctcaaaaata aatgtgggaa caaaatattt aaaaatagga
     8161 tagtgaaagg atagtgaagg atagtaaaag gagggtagta ggatagcaaa aaggataggc
     8221 tccttttcgc tatccttttt aaattggagg aattaatatg gaagtaagaa taagaaatgt
     8281 ggatgagaaa atcgtaagag aaattgatcg aagatgtgac ga
//
LOCUS       DADQDV010000098         7797 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.101, whole genome shotgun sequence.
ACCESSION   DADQDV010000098 DADQDV010000000
VERSION     DADQDV010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7797)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7797)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7797
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.101"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(105..629)
                     /locus_tag="J8S10_002656"
     CDS             complement(105..629)
                     /locus_tag="J8S10_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAZ9631217.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(622..1095)
                     /gene="tsaE"
                     /locus_tag="J8S10_002657"
     CDS             complement(622..1095)
                     /gene="tsaE"
                     /locus_tag="J8S10_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HAZ9631218.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(1218..2198)
                     /gene="pta"
                     /locus_tag="J8S10_002658"
     CDS             complement(1218..2198)
                     /gene="pta"
                     /locus_tag="J8S10_002658"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HAZ9631219.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(2351..3031)
                     /locus_tag="J8S10_002659"
     CDS             complement(2351..3031)
                     /locus_tag="J8S10_002659"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HAZ9631220.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            3157..4026
                     /locus_tag="J8S10_002660"
     CDS             3157..4026
                     /locus_tag="J8S10_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAZ9631221.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            4052..4567
                     /locus_tag="J8S10_002661"
     CDS             4052..4567
                     /locus_tag="J8S10_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631222.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(4614..5177)
                     /locus_tag="J8S10_002662"
     CDS             complement(4614..5177)
                     /locus_tag="J8S10_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAZ9631223.1"
                     /translation="MIRFARKEDAPEIAPLILVILKDMELPFLKQTGEQKTLEILEEA
                     ITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKYQLDASTRLFI
                     DKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLSVDEKNPKAKK
                     LYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(5232..5411)
                     /locus_tag="J8S10_002663"
     CDS             complement(5232..5411)
                     /locus_tag="J8S10_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631224.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(5488..5997)
                     /locus_tag="J8S10_002664"
     CDS             complement(5488..5997)
                     /locus_tag="J8S10_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631225.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(6093..6473)
                     /locus_tag="J8S10_002665"
     CDS             complement(6093..6473)
                     /locus_tag="J8S10_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAZ9631226.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            6803..7552
                     /locus_tag="J8S10_002666"
     CDS             6803..7552
                     /locus_tag="J8S10_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HAZ9631227.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
BASE COUNT         2232 a         1614 c         1382 g         2569 t
ORIGIN      
        1 tattcaaaaa aaatggactg cgacacgact tttgtcacag tcccttcgtg tgtttttctg
       61 ccttctcaaa aggatgacag tttctcactc ttttcctatt tcttctattc aatcaaataa
      121 ctcattttat atacatctaa aaattcacct agatctgttc ttgcccctct aggcatgacc
      181 gcttcgattt ggaagcccat ttttcggtaa aggtgtacgg ctctttcatt acgaacttga
      241 acgtcaagct ccaatcgaaa aagtacaccc atttccttcg cccaactgat gatttcttct
      301 agcataagag tgcctagtcc cattccccaa tattcctgca gaatactgat accgacttct
      361 cccacgtgag acaaacgaaa ttgactgtct gccttgacag atgctgttcc aataatcgtc
      421 ccttcataga ttgcaagcag caataaatta ttattgcttt cgtatatata atccaactct
      481 tcttctaagg tttctggtgg taacaggagt tctgcttcat ccaaaactaa aaattctgtc
      541 tccttattaa cttgtcccat catcaaaaga atgtcttttg catctcctgg cactgcttcc
      601 cgcaagatga tcccaacttc ttcactcatg attttcagcc catttttcta gaattcgctg
      661 tttgaaggtt tcactttgct ccccgtatga gattagtttc acataccgct tttctaaatc
      721 tgtatcactt ttttctaaaa tcagttccaa ataatcctcc ggcagtgctt cttctaatag
      781 atttccccat tcaacaacgg aaagcccatc accttcaaaa tattcatcta accctaaatc
      841 tgctccgcta gctgctaccc gataaatatc catatgatac aacggaatcc gaccttgact
      901 atattctcta ataatcgtgt atgtcggact tttgatcatt tgcgttatcc ctaatccttg
      961 ggcaattcct ttcgtcaacg ttgttttacc cgcacctaga tcaccagtca atatcagatt
     1021 gtcacctggc attgcggaat gaccaattgc ctctgcgaat tgttctgtca ttgttaatcc
     1081 tgatagttcg atcatttttc atcttctccc gctcttcttt ctttttgcca gtatatcgcg
     1141 taatgaagtt tttttaaaga aaaaatgaac tagtcaagaa cagcagctgc tgtttttggc
     1201 tagttcgcgt gtatttgtta atcaatcaat gtttgtgctg ctgtgataat cgataattta
     1261 tatacatctt cttcatttgc tccacgagac aaatcagaaa ccggtttgtt caagccttgt
     1321 agaattggtc cgattgcttc aaagttaccg aaacgctgag caattttata gccgatattt
     1381 cctgactgca attctggaaa tacaaagact gttgcttgac cagctacttc tgaatctggc
     1441 gctttcagtt gtgcaactga aggaacataa gaagcatcaa attgcaattc gccgtcgatc
     1501 atgtattgtg gcgctagttt tttagcgatt ttagttgctt caactacttt gtctacttct
     1561 ggcgatttcg ctgagccttt tgtcgagaag ctcatcattg ctacttttgg ttcgatatcg
     1621 aacaattctg ctgtttttgc agaatctacg gcgatttcag ccaattcttg cgcagttgga
     1681 ttcacgttga tcgcacaatc cgaaaagaca tatttttctt gatctcttcc acgtaccatg
     1741 atcatcgctc cgcttgtccg actgatgcca ggctttgttt tgatgatctg aagtgctggg
     1801 cgaacagtgt cgccagtcga atggatcgct ccagagacca ttccgtctgc aatccccata
     1861 tacgtaagca tcgtaccaaa gtaattcaca tcttttaaaa tcttttctgc ttgttctttg
     1921 gatgcctttc catttctacg ttcaacaaaa gtatccacca tttcatccca cttatcgtaa
     1981 ttatcagggc tgatgatcgt aaagctagat gttttgattc ctctggcatg cgctgcattt
     2041 cttatttctt cttcgttccc tactaaaatg ggttccacaa gttcttctgc tttcaaccgg
     2101 gcagctgcgc ctaaaatacg agcatcagta gcttccggga aaacgatttt gatcccacgg
     2161 cgaacaattt taaatcttaa actatcaaac aattccacaa gatgacctcc agacgttttt
     2221 atatgtatta tcatacacta ttccagaaaa aaagaacagt ttattttatc tgtatcagtc
     2281 aaaaatgctg gaaaaattaa gtttttcaca tacaaagcga actgcactat aacaggaaag
     2341 cgctgtttta ttacactgtt tcaggcagtt gccaatcaat cggttcttct cctaacgcaa
     2401 ggagcgcatc attcgttttc gagaagggtt tggaaccaaa aaagccacga cttgcagata
     2461 acggactggg atgtggagat gttatgatga tatggcgact cttatcgatc attttgattt
     2521 tttcttgtgc cggttttccc cacaagataa acacgattgg tttttcccgt tcatttaatt
     2581 tttcaatgat cgtgtctgtt aatctttccc aacctttccc gcgatgagaa tacgcttgcc
     2641 cttcccgaac ggtaagaacg gtgttgagta aaaggactcc ctgtttagcc catgacacta
     2701 gatttccatg ttgaacaggt gcgattccaa gatcatcata aagctcttta tagatatttc
     2761 ttaacgatgg cgggatcttt acgccaggtt gcacagaaaa agataagcca tgagcttgat
     2821 tttctccatg ataaggatct tgtcctaaaa tcaccacttt aacttcttca taaggagtca
     2881 attccaatgc ttcatagata tgatacatat ctggatggat cttttgggac gcatattctt
     2941 tttttaaaaa ttctcttaga tgcagataat aatcttttga aaattctgag gacaaaactt
     3001 cttgccaact gttatgaatg atttctttca aaaactccac ctcctaataa aaagaataac
     3061 tcacattttc ttcaatcaca agggacaatc ttcaccctca gcacttgatt aatatggtaa
     3121 actaggaaca agaagcagaa aggaacgata atcattatga tcaaattaat tgcatcagat
     3181 atggacggca cattattaga tgcccatatg agtgtttctc ctgaaaatgc cgaggcgata
     3241 cgttttgcaa atgatgccgg tgttgagttc atggtcgcta ctggtcgaaa ctatcaagaa
     3301 gctcgcgcag ctttagatga ggtaggaatc gattgtgcga tgatcacttt gaacggggca
     3361 caggtatttg ataaagaagg aaattcattg tttaccgtgt cgattccaaa taatcaagca
     3421 atctctgttt tagatattct agatgctaac ggtatttact atgaagtagc aaccaacgat
     3481 ggtctttatt ctgaaaatca agcgaaacga attgaaagtt ttgcttccat ggtggctacc
     3541 catttacctc accttacgta taaaatggcg attgccatgg cctcagctaa gctggagtta
     3601 ttgcacatca catacgtgga cagtattcgt gctattttgg aagaaaagaa tctggaagtt
     3661 ttaaaaatta tttgttttca tacagaaggg ccagctgtat taggtccagt tggaaagcag
     3721 atttctcttt taggcgatct agccgttact tcctctggtc aaaacaatat cgaagtgaac
     3781 cataaaaacg ctcaaaaagg aattgctgtt gcccatgtcg ctcacgagcg tgggatttct
     3841 ttagaagaag tcatgacgat tggcgataac ttcaatgatg tcagcatgct gcaagtagca
     3901 ggagtcagtt tcgcaatggg aaatgcagaa atcgaagtaa aagattatgc caaatataca
     3961 acggacacaa accttgaatc tggcgtagga aaagccatat tgcgcgcgat tgcagaagac
     4021 ttgtagtttt atctagaaaa gagggatata gatgtcagaa tttttcattc aggaaaagca
     4081 gcttggacgt gcaactcgga caattgtcaa aaacgaaaaa ggacattccc tgtttttgat
     4141 ggttggtcgc tggggaacaa agggcgatgc attgtctctt tatgccatga atggcgatct
     4201 cgttgctcac atcaagcaga taagcctgac attcggtacg cgttttgagc tgtataaaga
     4261 gttcgaaaag gtgggaacca tgcagaaaat attcaattgg cccggtgact tttattatat
     4321 tcgtagactt cactggacag tccaaggtga tatctataat catcaatatc aaatccatca
     4381 tttcaatcag caaatcatga aaatggataa agcaacactt ttttcaggag attactatgt
     4441 attggatgtc tcaaatgatg aagatgctcc agtttgtatt tgtattgctg cggttttaga
     4501 ttactggctc taccgtaaag acaaaagtcg cgataagcct gtttcttacc gacttaactt
     4561 aagttaaaaa gatgtacctg aaatgcggaa atacgcattt caggtacatc tttttagata
     4621 ttcttttgca tatgatcata aagatgacca ctgatcatcc gctgaccgac aactttgaag
     4681 tcatggcgtt cgtataattt tttagccttt ggattttttt catccacact tagaccgatg
     4741 acggagcgat tagctttctt cgccaattta ggtaatgctt ctaataatcg cgaaccgatg
     4801 ccttgtcctc taaaatcttc tgatacactg atagagtcca aataccattc gttgggaaac
     4861 gtttctttat caatgaacaa acgtgtagac gcatctagct gatatttctc taagataggt
     4921 accagtggct gatcgatgat tgattcttct tcatctgtat aaccgtaagc aactcctgca
     4981 actttaccgt ctatttcttc tacgatacct cgtgaataac tgtaacgata atttggatca
     5041 gtgattgctt cttctaaaat ctctaaagtc ttttgttccc ctgtctgctt caaaaatggc
     5101 agttccatat cttttagaat cactaagatc aatggggcga tttctggagc atcttctttt
     5161 ctcgcaaaac gaatcatagt ttcctctcct tttctccatt ctaacatgca gaaaaagaaa
     5221 tcgcaaaatc gttattttaa aaaatcttca atcttttcag taatgaaata accatgagta
     5281 acgattcttg ccgcttcagt tcggcaataa gggcagacga ctggcatttc tttatcatta
     5341 tgttcgacta cattattgac ttcttcgtat gcaaattttt ttccgcaatt agggcatttc
     5401 attttttcca tgttatctca acttcctttc atctttactc tcttagctta ctcttatatt
     5461 gtaaaaaaga gaagcaatat ccttcttcta tgcagatatc catacctgac ggtcctgttc
     5521 tccatctatt aatcggactt tataataagg acgttcatct ttgactagaa gtgtccactc
     5581 tttcactttt gcttttttcc cgtagtagct gactgcttcc ttcatcgctg cttgcggttg
     5641 tttgaactct tccgtttttt ctatatcaaa aagatgttct gcggcctttt ccgtgtcatt
     5701 tcgtacggtt gttttcccag tggatggatt gactgctatg acttgtcctt cacaaaaaaa
     5761 ctggtattca tatgttgcat tcgtaggatt ctccaaatct ttttcaactg caaaatgaat
     5821 agcagatatg ttatgttctt ttgtttcgtt ttttacgatt gctgctgctt ttttcaatga
     5881 gatccgatat tcctggtcac taatatcatc catgtgaaaa gcggcattga gcagtcccgt
     5941 cataccggta atccctatta cgatgagggc agcaacacca aacatcattt ttttcattct
     6001 tcattctcct gtttcttttt tttaaagaat atcaagaaat gaacgaatga aaaatcgaat
     6061 gaaacgaaaa aaaagtgaca attttgttat ctttattcgt gcagttctaa tggcaatccg
     6121 tctggatcaa agaaaaacgt catttttttt cctgtaaagg tatcttctct aatcggttct
     6181 gattcgatcc ctaaggactg caattctgca attgtttctt caatatcgtc tactttgaaa
     6241 gcaagatgac gcaagccaca agcttctgga tagtttggtc gttgtggcgc attagcaatt
     6301 ccaaaaatct ccaattcagc acttcctagt ttcagatcta atttatagtc atctcgttct
     6361 ttgcggtaat tttctctgat tacttcaaat cctaatttat taacataaaa atcacgtgat
     6421 ttctgataat ctgaaacaat gatggctata tgatggatcg ttgtaaggtt catatgagca
     6481 ctcctattct tcgtttaagc tcggatctat attaatctcc agttccattg taaatgtgtc
     6541 agattgaaaa aaatagctgt ttttcctttt tataagaaaa aaggcaaaaa aaacagaaag
     6601 taggtcctcc aagacactct tcctgttccc aatataataa atgaaagtaa gaaattatat
     6661 tttcaagaaa acaaacagaa aattatcata acacaaatta tttataattg aaagactagt
     6721 tttttttcaa gaaaagcata caatagattg tgttagtaaa tacagaacac actacattta
     6781 gtgtcttaag gagtcctcat acatgaagtc atattttcag tttttagctc atcagctaaa
     6841 aggctggccg caacaaaatt attatctttt ctttttcagt cttggctgcc aggtcatgac
     6901 tcttgtcaat agtcccatca cttggctgtc cgttattaca tttatcggta ccacgcttgg
     6961 tgtattgtgt attttatcca tcaatgcggc aaaatcagtc aacggtattt taggtatttt
     7021 gtctgcgatt tgttttatta tcgttgggtt ttcagcaaag aactatttaa gtatcggtga
     7081 acagattgct tatatgatca cattggatat ccccgtattg ttaagtaaag aatggaatca
     7141 taatatggct tcaaaaatcc gaaaattcac tggaaaaagc tggtttatcg caatcatcag
     7201 tactttcctt gtctatcttg tttcaggatt cctgattggt cgttatacag atgatcctcg
     7261 gccgtgggta gatgccattg ctttttctat tagcttgact gctggtatca tcagtttctt
     7321 gcgttacaac aaccaatatt actggtggtt agcttcaggg cttgctcaaa tggtcctttg
     7381 gtatatttca tttacgcatg gatctgcaag tttggcgatg ttcgtgaaca gctctgttta
     7441 cttgctgaat gatgtccttg catttaccgt ttcaccttgg tataaccaaa aagaacgtga
     7501 acgtatgcaa aaaatggaag aagaatacta caacgcacaa caacacgcat aaaaaaactg
     7561 agcgtgggac aaaagtaaag aacacttttg tctcacgctc taaacacgta taaacggcgg
     7621 aatcagaagc aactccttcg gaaataagct gaaattcaca aaaatttgaa aagcaatttt
     7681 cgtgaatttc ttcttatttc ttggagttaa acgcttctgt cccagcctct atttcctacg
     7741 attagtcaag taaaaggtgc aagaaaaata gctcgtaaac gaaagcgaca aaatcaa
//
LOCUS       DADQDV010000099         7760 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.102, whole genome shotgun sequence.
ACCESSION   DADQDV010000099 DADQDV010000000
VERSION     DADQDV010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7760
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.102"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(552..1898)
                     /gene="gor"
                     /locus_tag="J8S10_002667"
     CDS             complement(552..1898)
                     /gene="gor"
                     /locus_tag="J8S10_002667"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HAZ9631228.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(2032..3273)
                     /locus_tag="J8S10_002668"
     CDS             complement(2032..3273)
                     /locus_tag="J8S10_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HAZ9631229.1"
                     /translation="MTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAYGLRS
                     RAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISAVIVS
                     DPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVAEIRK
                     NTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFGQERN
                     SLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNVYKAA
                     VDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVYKFVG
                     EVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRAPNPM
                     MILTMPVAQPVKPGDMIRKRK"
     gene            complement(3291..4214)
                     /locus_tag="J8S10_002669"
     CDS             complement(3291..4214)
                     /locus_tag="J8S10_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HAZ9631230.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(4435..6927)
                     /locus_tag="J8S10_002670"
     CDS             complement(4435..6927)
                     /locus_tag="J8S10_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HAZ9631231.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(6934..7401)
                     /locus_tag="J8S10_002671"
     CDS             complement(6934..7401)
                     /locus_tag="J8S10_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HAZ9631232.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(7537..7610)
                     /locus_tag="J8S10_002672"
     tRNA            complement(7537..7610)
                     /locus_tag="J8S10_002672"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7574..7576),aa:Arg,seq:acg)
     gene            complement(7668..7741)
                     /locus_tag="J8S10_002673"
     tRNA            complement(7668..7741)
                     /locus_tag="J8S10_002673"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7705..7707),aa:Pro,seq:tgg)
BASE COUNT         2161 a         1691 c         1247 g         2661 t
ORIGIN      
        1 aaatcagtgt tttgtcctga gtattagaga aacaaatgga aaaatagttc ctcatatttt
       61 gccgtttttt gagctaatac cgaaggacag ctgattgaac actatttgtt cggaaaaagt
      121 gactaactat gacacaattt ttttcacagt cccttttttc acttgatttg attcgtacca
      181 gcgaacttga cgagaacttt cttggtttgg taactatatg gtattctttt aacatcctcg
      241 tttgcttctt ctaatttatt tatacaaagt cacacttttt taaacatctg ttcttcgata
      301 catttctatt tcttttaaac atcgatacca atattttgaa cttaagagtg cataccaaat
      361 ggattcattt actcttcgtc agttacgaag ataatcaaaa tctccaactt ccctacttat
      421 ttcgttttga gaattatcga agcaatctta cataaataac taaaaaacaa aaaaccagaa
      481 aatcagtata ctgattttct ggttttacat ggtttgttca ataaaaagct gttggaactg
      541 ttaatattaa attatcgcat cgttacgaat tcttccgctc ctgttggatg gatggctact
      601 gtattgtcaa agtcttcttt agttgcaccc atcttgatag ccacggcaaa accttgcagc
      661 atctcatcga caccaacacc aatagcatgt aagccgacga ttctttcttc ttttccgaca
      721 cagatcaatt tcatttcgca tttttggcga taatcattta atgcaaagta cattggggta
      781 aagcgtgaac gataaacttt caattcattt tcgccatatt tttccaatgc ttcttcttct
      841 gtcaaaccaa ttgttgcaat tggtggatgc gtaaagacga ctgtcggaac aagtttatag
      901 tcaagataag aatctttctt tccattaaat aaacgttctg ataaacgtct accagctgcg
      961 attgcaacag gagtcagatc taatttaccg atcacatcac caacagcaaa aatatgttca
     1021 tccgttgtat tttggtattt atctactttg ataaaccctt ttttgtccaa ttccacattt
     1081 gtattttcca gacctaattt ttcggtattc ggtacacgtc caccggcaaa aagtacacaa
     1141 tcaccagtta aggtttcacc attttcaaat agcaccgtat attcgtcatt gtttttagta
     1201 atttctttag caatatgatg tgcgtaagtt tttattccag cttcttggta catttggatc
     1261 aaattgtccg aaagcatttt atcaaacgtt ctaagtggtc gttcttttcg atatgcccac
     1321 atgacttcac tacctaaacc acgaaataca cctgaaagtt cagccgcaat gtatccagca
     1381 cctaaaacga ttgctctctt aggtaactct gttaattcaa aaaatccatt tgaatcaatt
     1441 gcgtattctc caccaggaat ggtcatttta cttgcacggc ctccagtagc gatcaagatt
     1501 ttaggagcac gataggtttc accgtttact tcgatcgttt gactatcgat aaaagtagcg
     1561 taacctttta tagcctcgac atgattgcta tctaatcctc tttgataagc accgtgtaga
     1621 aaatcaatat atttttctcg tctttctact agaccggcga aatcaacatt ttttaaatct
     1681 gcttggatac cgtaacttga ggcatctcgt tcaattgttt ccaaaatcgt acttgcttgc
     1741 cacataactt ttttaggtac acaaccgacg ttgacacatg ttccgcccaa ttcattcgct
     1801 tcaatcagca aaacttttgc gccatgcatc cctgctctgt ttgctgaagc aataccgcca
     1861 gagccgccac caattacgat gtaatcatat atttgcattt tgttcctcct tattgaagag
     1921 atcaatcaaa acctttattt aacgatcctt tttctacaga aaacaagtgt aacacttttc
     1981 ttgaattttg tatgcgaaga tgcttaaaac agggatatat cagctttttc cttatttacg
     2041 ttttcggatc atatctccag gtttcaccgg ctgtgcgact ggcatagtta aaatcatcat
     2101 tggatttggt gctcggtcaa tggattcgcc ttcttcatta tgcataactt caacggtttg
     2161 actgaaatga ctgaatcctg gaccataaaa ttcgatttca tctcctacag aaaacaagtt
     2221 tctctgacgt atcgtagcaa tctgtgttgc ctcatcataa gataatactt caccgacaaa
     2281 tttatatact gggattttac gacgttcacc gaataattgt tcgttttcag ttggtgtatt
     2341 gtagtaaaaa cctgtagcta attctcgttg tgctactttc cataactcgt cgatccattc
     2401 ttgcttgcag acatagtttt caggatcttc catataactg tctacagccg ctttatagac
     2461 atttgacacc gtagatacat aatggatcga tttcattctt ccttcgatct tgaagctgtc
     2521 tacgccgttt tcaatcaatt ctggaatatg ttcgatcatt gacatatcca ctgcactcat
     2581 cgagaattct tcttccactt cgcctgtatc agttaaactg tttcgttctt gaccaaaagg
     2641 catatcgaac aatccatact tccagcgaca agattgagaa catccgccac ggtttgcatc
     2701 ccgcatcgac atatggttgg acaatgtgca tcgaccagaa taagagatac acatggcacc
     2761 atggataaat gcttcgattt cggtatccgt atttttacga atctctgcca cttcctccat
     2821 tgaaacttca cgagctaaaa cgacacgttc caacccttct tctttccaga attccaatgt
     2881 ctcaaaatta gttgctgaag cttgagtgga taaatggatc ggcagacctg gggcttctgt
     2941 cgcacaaatt tcgatcaaag ctggatcaga aacaatcact gcagaaatac cgacatcacg
     3001 caaactgcgg aaaaattccc ctgctccatc ttcatttcct tcatgggtga ccatattagc
     3061 agcaacgtat accttcgcat catgttcttt tgcaaaagca actccttcag ccatttcttc
     3121 ataagtaaaa ttacctgcac ggcttcttaa accatatgca ttcccgccaa tatatactgc
     3181 atctgctcca taatggatcg cggtttttaa cttttccagt gttcctgctg gcgctaggat
     3241 ttctggtcgt ttcaattttc tttttactgt catttctttc atcatactcc ttatttgata
     3301 gcagaaggat caatataaaa gaatcctgta tctaattcac ggttttcagg atgcaattta
     3361 ctgatttcgc tagtcatttt ttccgctttt tcttgatccc agctaccttc taaaatttgt
     3421 ttttttgctt cggcgaatag tcgagtgatg tttacgaatt tttcgcctgg agtaaataat
     3481 ccgtccaatt tccatgtaca gtaatgatgc tgataaagtt cattcaattc attcgagaga
     3541 ttcagatcat tgctggcaaa aatatgtgtg ccatgactat cttcataaat agaataatgt
     3601 gtctcttctt ttttaggttc cgagataaaa agacctcttt cacgatcttt ttgttcgtct
     3661 tgtttcgtat agttatagta attctgtagc agtggacgtt tggattgatg gatgcatgta
     3721 gcaccataca caagggtttc tacaggaata tcgagttttt cttccatcgc cttcatctct
     3781 tcaaaaggaa cttcacgagc aagtactgct ccaactgcgc cttttttcgc ccagaaattg
     3841 atttgacgtg cgctcgttac taatgtttca gcatcataaa tatacggtat acgcaattca
     3901 ggattttttt tcatcgtata aataatacct gtatcaccaa ctgtgatcac atctacgttt
     3961 atttctttta aaaaagccaa atattcaggt acatttttca ttttttcagg atgaatgatc
     4021 ccatttacag caatattcgc ttttttacca tacttgtgtg ctaattctac caattgtcgc
     4081 tgttcttctc gtgtaaatga agcaggcaga cgcaatccaa attgctcttc accgaaatat
     4141 agtgtatctg cacctgcagc aagcaactgt tctgcttgtt caatagtttc tactgtggtt
     4201 atgagttcga tcataatttt ctcctcctac aacttcataa tagtagcata gctctaaaaa
     4261 ctttccaata cttcttctat ttaaagtcgg atttttgaaa attatttcac aaaaaatcaa
     4321 aataaagttc gatatattct gtccaaatat aaaaagagat tgtgacaaaa atcttgtcac
     4381 aacctcttaa tcaagtctta ctattataaa aattcagcta cacaggccaa gtaactatag
     4441 ggaacctact gtttcctttt taggtccgcg aacattcaat gtgatcttac cttttgaagc
     4501 acctactgtt acgtggtcac ctaaacgaat ttctccgcca agcaaagcct cgctcaatcg
     4561 atcttcaatt tctttttgaa gtgcgcgacg gattggacgt gcaccatatt caggatcaaa
     4621 tccagctttc ccgatcacat cgattgcaga tggtgtgatt ttcacttgaa tatcttgttc
     4681 tttcaatcgt ttgataatcg ctttgctcat gatttggacg attgtatgga tttcatcttt
     4741 actcaatgaa tggaagacga cagtctcatc gattcgattc aagaattcag gtcggaaagc
     4801 tttctttaac tcttctaaga tacgtttttg catggctttg tgatctttag taacatcttg
     4861 gacattgaat ccgacatttt tttcttctcg aatttgtgtc gctccgatat ttgaagtcat
     4921 aatcatgatt gtatttctaa agtccacttt tctaccttta gaatctgtta aatgaccatc
     4981 atccaatact tgcagaagta aattgaaaac gtctggatgt gctttctcca cttcatctaa
     5041 gagaatcact gaatatggtt tttgacgaat tttttctgtc aactgtccac cttcatcata
     5101 ccctacgtat cctggaggag acccgattaa tcggcttgta ctgtattttt ccataaattc
     5161 tgacatatca acacggatca gggcatcttc acttccaaac atgacttctg aaagtgcttt
     5221 ggccaattct gtttttccga caccagttgg tccaaggaac atgaatgaac caattggacg
     5281 atcaggatct ttcaatccgc ttcgtgcacg gcggatcgca cgtgaaactg ctttgacagc
     5341 ctcatcttga ccaacgacac gttcatgcag aagtccttcc agttctaaca agcgttcgct
     5401 ttcttttttc tccaactgct gtagagggac accagtccac tccgatacaa ctgtagcaac
     5461 atcttcttct gttacacgat cagaataacc ttgctcctgt tttgcttcaa ttgcagaaac
     5521 tttttgcagc tttttacgta gtgctttttc ttgtctgcgt aattgagcag cattttcaaa
     5581 gtcttgtttt tggatcgctg cttccttttc ttgtactagt tcatcgattt ctagtttgat
     5641 cacagttgat tttgttaagt gatcggtttg atccaaacgg actttcgctg ctgattcatc
     5701 gatcaaatca attgctttat cgggtagttg acgagaagtg atataacgaa cagaaagatt
     5761 gactgctgct cgtacagctt catctgtgat ctccactcca tggtgctctt catatcttgt
     5821 acgtaatcct tgaagaatca cttctgcttc ttcaggagtt ggctcatcta cttgaatgcg
     5881 agcaaaacgt cgctctaatg cagaatcttt ttcgatatat ttttgatatt catctagggt
     5941 cgttgctccg atcgtttgta attctcctcg agctaacgcc ggtttcaaga tattcgaagc
     6001 atcaattgct ccttctgctc cacctgcacc aattaaggta tgcaattcat caatgaataa
     6061 gattacttga ccatcattat agatttcgtc gatgaccttt ttcattcgat cttcaaattc
     6121 accgcgatat ttcgtaccag caaccaaaga tcccatatca agcatcatca ggcgcttttc
     6181 ttgcatgtct tctggcactt cacctaaaat gattttttga gctaaccctt cagcaatggc
     6241 tgttttgcct acaccaggtt cacccaccag tacagggtta ttctttgtcc gtcggctaag
     6301 aatctggata agccgtttca cttctctcga acgaccaaca actgggtcca gcttgttttc
     6361 ttttgctaat ttcgtcaaat cacgtgctaa tgaatctagc gtaggtgttc cttgcggtgt
     6421 ttgccgttta tcttgtacat ttacatttct acgacgattc attccttttc cagcagaatc
     6481 accagctagc cccatttttt gtttcagaac ttgacgggct tttgaaaggc tgatacctaa
     6541 gttgatcatg attcgagtag ccatgatact ttcatctttt aataagctca tcaaaatatg
     6601 ttctgttcca actttttgag aaccagtttt cttcacttcg ctgctagcta aagcaaaaac
     6661 ttgtttcatt cttggtgaat atggaagaaa gactccttta gggtaagaac ggataccacc
     6721 ataaccaatc agatgttcaa tttcttcata aatttccgtt tcattcaaat ccatttcacg
     6781 taatactttt ccagcaattc cattttgctc gaccactaag gctagtaaaa catgttctga
     6841 actaactgat tgatgtttca accgttttgc ttcttcttgt gcaatttcta atactgcttg
     6901 ggctctttca gtaaaaagtt cttccatcta atctcacttc ccatcttcat aacttaaacg
     6961 ttccagaaat gctcggagaa tccgagcacg tgtatgatct tcatattcat tgaaattcaa
     7021 tgtgtttttt gcaattgcac tcaacatcaa gtttccttct ttttttgtaa ttatttggtc
     7081 ttcataaagt ttttgaataa tagcaaaagc atttttctca ctgattgtat catcaaataa
     7141 ctgatttatc tgctcaagta attgtttttt atctgaaatc cttacttttg caattcgtat
     7201 ataaccacca ccaccacgtt tgctttctac tagataacca cgttggatgg taaaacgggt
     7261 attaatcaca tagttgattt gtgaaggaac acagttaaag aggtctgcca tttcaatcct
     7321 tcgaatctcg atcatttcac tattttccag aattttcttt atatatgatt caattaaatc
     7381 cgaggtattc tgatgtgcca tcttattcat tccctttgac taatattgac cttaattata
     7441 acgaatttga taatagaaag aaagaagaac gctttttgtt aaataaatcc tttagaatca
     7501 acaaaaaaaa atacggaata tactattccg tatcgacgcg cccaagagga gtcgaacccc
     7561 taaccttttg atccgtagtc aaacactcta tccagttgag ctatgggcgc atattcaatt
     7621 taaaaaaatt ataaatcatt tgaaaacaaa aagcaagata aaaaaaatcg ggaagacagg
     7681 attcgaacct gcgacccctt ggtcccaaac caagtgctct accaagctga gctacttccc
     7741 gtttaaaaaa taaaaaagac
//
LOCUS       DADQDV010000100         7598 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.103, whole genome shotgun sequence.
ACCESSION   DADQDV010000100 DADQDV010000000
VERSION     DADQDV010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7598
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.103"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(136..426)
                     /locus_tag="J8S10_002674"
     CDS             complement(136..426)
                     /locus_tag="J8S10_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631233.1"
                     /translation="MGEKKIKGAGILLVMSKALFLLPCTFMFIVLCYFKRRKKWCWID
                     VLLFLPFFPLIYFLEEIWDDMACDSAFLFSHSLGLMISLTIFAIVLFFLNKK"
     gene            complement(544..804)
                     /locus_tag="J8S10_002675"
     CDS             complement(544..804)
                     /locus_tag="J8S10_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631234.1"
                     /translation="MGVDHLIVLSKLLFWIPFIIMTSAFFYLFKRPNKYLLLSACPMI
                     YFIHKIRGFYYYDSGISLFCYEIGLLASAIFFIFVLEYFRKK"
     gene            complement(941..1354)
                     /locus_tag="J8S10_002676"
     CDS             complement(941..1354)
                     /locus_tag="J8S10_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HAZ9631235.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1810..2295)
                     /locus_tag="J8S10_002677"
     CDS             complement(1810..2295)
                     /locus_tag="J8S10_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631236.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2434..2649)
                     /locus_tag="J8S10_002678"
     CDS             complement(2434..2649)
                     /locus_tag="J8S10_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HAZ9631237.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2873..3673
                     /locus_tag="J8S10_002679"
     CDS             2873..3673
                     /locus_tag="J8S10_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAZ9631238.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3692..5560
                     /locus_tag="J8S10_002680"
     CDS             3692..5560
                     /locus_tag="J8S10_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAZ9631239.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5553..6044
                     /locus_tag="J8S10_002681"
     CDS             5553..6044
                     /locus_tag="J8S10_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HAZ9631240.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6032..6586
                     /gene="srlA"
                     /locus_tag="J8S10_002682"
     CDS             6032..6586
                     /gene="srlA"
                     /locus_tag="J8S10_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174078.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HAZ9631241.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6604..>7598
                     /locus_tag="J8S10_002683"
     CDS             6604..>7598
                     /locus_tag="J8S10_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HAZ9631242.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2707 a         1213 c         1443 g         2235 t
ORIGIN      
        1 tgttactatg aataacataa taagaaagta aagtggattg atttgagatc tttttatact
       61 tcaaaaaaga taacacccaa ctttcaaaaa tatgttttgg aagttgggac aaacgagtta
      121 atacatttta atacattatt ttttattcaa aaaaaatagc acaatggcaa agatcgtaag
      181 agagatcata agccccaatg aatgactaaa aagaaaagca gaatcacatg ccatatcatc
      241 ccatatttct tcaagaaaat aaataagcgg gaaaaaggga aggaatagta gaacatcgat
      301 ccagcaccat ttttttcttc ttttgaaata acataaaaca ataaacatga acgtgcaggg
      361 aagtaaaaac aaagctttac tcataactaa caaaatacca gctcctttta tttttttctc
      421 ccccacattc aaagagtaac aatggtatgt acttaataat agaaaaatgg atcaacttgt
      481 atgaataaca gctgaaaaga tctgcaccaa ataaaaaact tccagccaaa actgactgga
      541 agtttatttt tttctgaaat attctaacac aaatatgaaa aagatggccg aagctaataa
      601 gccgatttcg tagcaaaaca atgagatacc agagtcgtaa taataaaatc ctctaatctt
      661 atggataaaa tagatcatcg gacaagcaga taagagtaag tatttgttag gccttttgaa
      721 taagtaaaag aaagcactgg tcattatgat aaatggtatc caaaacaaaa gtttacttaa
      781 gacaatcaaa tgatcaactc ccatattttt taccaagaga gatcataaca tctttatcgt
      841 aaaaacaaaa tatttttttg ctcattttga aaatttaaac atactcgttc ttatccaaat
      901 atataaaaat cgcccctcat tcatcgagag gcgataagtt ctaatttaac tcaatttttt
      961 ttgtttcttt tggctgataa gctgttttag gtaataccaa tttcagcaca ccgtttttaa
     1021 aggttccagt gattttttct tcatcaacat taggaagata gaatgaacgt ttgtaagaga
     1081 ccgaatgtct ttctttccgt acatagttgc catcttcttt atcttctgta tgggactcat
     1141 gattggcgga gatcgtcaaa gtattatctg aatattcaac tgtcgtgtct tctttgtcac
     1201 agccaggcat atcagcagtt agtttgtatt ctttttcatt ttcgactaaa tctacttttg
     1261 gataacttga aacacctaaa aaatcattga atgctggact aaacacgtca ttgaaatcag
     1321 ggaacatgtc gcgaatgcta ggtacatttg ccatttttga tcatcctttc aataagtatt
     1381 ttttatttat ccctatttac gtaataactc tattttgaaa aaaatgcaag tataatggtt
     1441 agctttgtga atatttcatc taatacgata caaaggctat ctttctaatt tgaaaaaggg
     1501 atcattaaaa taataagaag aaaatatgtc aaaaggtaaa aaagtaaatt cttctatcca
     1561 aatatagaaa aattgaatct agaaaaccgc ccgacaataa atttcattaa ctcagttgac
     1621 cgaaaatgaa gtagatacca aaaatttatc aagagagcaa gtagagaagt gagtatattc
     1681 ataagagaaa tagctgtaac gaattattag gttaatgcaa atgcttattt atactccgta
     1741 taactttctc agaaaaaatg ataccaataa tgacttgcta gtactgtaaa tccgtataat
     1801 atcatctaat caaaatggtg ttccatttgc atctgtcatc gtaatcgatc cttcgggtga
     1861 cactcgataa aaaccaacgc ttccagatcc tccttgggaa cggatttgtt tgctggaagc
     1921 tgtgaacaaa taatctcgat caattttttg ataaaagcta ataacaatat cgtcactttg
     1981 taattcggaa cggtgggcaa taagaaatag aagtgctttg tcagagtttt ctaatggaag
     2041 agaaggtaca gtgctttctt gcatttcaga tgttgaagaa atgctaaacg actgaatact
     2101 tgattggcta tgttgcgaat ctacattacc agtagaagta ttagtaatgg aagtagtaga
     2161 agtactttta gttgaaccaa cctcagttgt tgaaatggct gctgaagatt ctttaacaga
     2221 attctttgtt ttatatccac aggcagaaaa aagtattaca gttcccaaca agcctgcgta
     2281 aatcccttta tgcatgatag ctcctcctaa aatagattat ctttattcag tatatcactt
     2341 aaacaaagaa aagcagatgg tttaaaatga aaaaaccttc ccaataaagg gaaggttcat
     2401 gaagataata acttttttaa taattatagc tttctaatat ctttcatcaa cttttctagt
     2461 aatcattggg aaaaatttca agcagtagat cgcacaaata cctacgacga tataaatgat
     2521 cttcgcaaaa atagttgttg aaccaccagc aatcatagct actaaatcaa gttcgaacaa
     2581 gcctaccaac agccagttca accctcccac aatcaataaa gttaatgcaa tagcatctaa
     2641 agttttcatt agaattctcc tttcttaaat gataaaacaa ttatatatca aaaagagaaa
     2701 cattgcttat ataacgctca ggaattttag caatctatgc aaaaagatga aaattttttt
     2761 tgctcttcca ttagtacaca ttttttagct gaagctgtaa atttcatgtc ttaatttttt
     2821 ttagtgagct tttatactgg atttgtaaga aaaaagaagg agaggatcac atatgtcgga
     2881 ttggttggat attgcaggaa aagtagtaat tgtaactgga ggttcctcag gaattggaag
     2941 aagtatcgtc gaaaatttgt tgaagcagaa tgcacaagta gcgaattttg atgtaactga
     3001 atgccgtata cagcatgaaa acctactatc tttaaaagtc gatgtgtctt ctaaaacgga
     3061 catagaagaa gggatatata aagtaatgaa acatttcaag acgatcgatg gtctagtcaa
     3121 taatgcagga ataaatattc cttctcttct aatagataga aatcatccaa aaagcaagta
     3181 tgaattatca gaacaagttt ttgataagat gatcgctgtc aatcaaaaaa gtgtatattt
     3241 gatgagccaa gcagttggaa gaatcttggt gcaaaaggga tcaggagtga tcgtgaatct
     3301 ttcttctgaa tcaggattgg aaggatcaga aggacagagc tgttatgctg ctacaaaagc
     3361 agcgatgaac agttttactc gttcttgggc aaaagagtta ggaaagagga atgttcgtgt
     3421 ggtaggtgtt gcaccaggga tactggaaga aaccggtttg agaacacaag aatatgaaga
     3481 agctctttct tatacgagag gtataagcgt cgaacagctg agaaacggtt acagtcgaac
     3541 aagtacgatc cctctaggaa ggagtggtaa gctgcaagaa gtggcggatc tagtctgcta
     3601 ttatctttca gaaagatcaa gttatatcac tggagtcacg actaatattt caggaggtaa
     3661 aacaagagga taaaggatag gggggacgca cgtgacgcta gtaaacagat ggtaccaatt
     3721 attgaaatta ctagtcactc acaagaaagt ttcaatccag gaagtgcaaa aagaaatcaa
     3781 aaccagtaat caaaccataa aaaaagatat tggggagttg aatgaagaaa ttgccggtat
     3841 tgcaaaaatc atccaaaaaa acaaacattt tgaacttgaa atttatgatt ttgatttttt
     3901 tgatgagatc atgcaaggaa aattgaaaac agccagtgat ttcaattcgg catccaaaag
     3961 aatcgcttat ttactaaata ggctgatcga aacagaggat ttcttacgta tggatgattt
     4021 gtctgaagaa gtcggtgtca gcagaggaac agtggtcaag gatctaaaga cattaaaaga
     4081 gatgatcaat gattttgatg taaagattac aggcacacca aataaaggac taagaataat
     4141 aggagatgag ctagaattac gactactttt attttatttt gtttctccct acttttcaga
     4201 gacgaaaaca gaacagtttc tagaagaaaa acaagcaatc aaacattttc agaagaagac
     4261 gaatgctagt aaacaagaaa tcaccctttt aacgaaagtt atcggtattt ctttgaatag
     4321 aatctctagt aactatctgt tgaagaagcc catcaatcgt tacagtgggt gttttgaata
     4381 tatccaagaa ttcaatgaac tgatcaatca gttggaagaa atctatgaac taactttgag
     4441 ccaatatgaa aaagatttta tcagttttcc tttgaacatc atcaacacaa gtataacgat
     4501 gataaggaaa gctaactctg atttgcgctt atatttcgac cccatgatga tgcgtattcg
     4561 acgattagat ctcattgatc tggatgagtc cttcttatat caagagatga aacagcacct
     4621 ctctttattg ataaatcggg taatttttcg ttatcgattg actgatttat tttatggtga
     4681 gatagaaaaa aagtatcctt tttcttacca aatcgctagc gaatgcatac aagcattaga
     4741 agctatcttg caacataaga tctctaaagt agagatcagc tacctaacgt tgtatttgga
     4801 gttagcattt cgatatcaaa aagagcattt ttcctctaaa aaagtagcca ttgttcatac
     4861 gacaggaaaa ggaacagcat taatgatcca aagacaaatc aaaaggatat tggggaggga
     4921 tatacaaata acacatgttt cagaagaaca atatgaaaaa gtagatctaa acaaatattt
     4981 cgctgttttt acaacgattc cgttaaaaaa tgtaaatgaa gagacaccgg tgatccattt
     5041 gactaatctt tttgatgact cttggttaag ggcacaatgg caaaaagcaa aaaaaaagcg
     5101 attagccggg tttcattcta ctgttttttt ctatcaaata tggaaagaaa aaaagacgta
     5161 tcaagaatat ttaaacaaat tagtcgctcc tttgatcaga ggctattatg tggatgaaga
     5221 atttgaaaaa aggatcttga aaagagaata tcagcaaagc acatttgtta acaaagaatt
     5281 tgcttttcct cacacaacca accagctatc tcaacacatt gttttatcag tagggctaat
     5341 aactgatcaa ggtttagcag aaacaggagg aaatggagtt atttttttat ttgccatacc
     5401 tgaagaaatg acggctgaag ttgagaatga attatttgag ctatacgata tcctatttga
     5461 actcataaaa atgggaatag atgagtttat tgaattagca ccgacacaag aatcattttt
     5521 aaaactaatc aaaagtaaag gagagagact tcatgaatga tatgtatcta ttcatagttt
     5581 tcgcagcttc agcttatgtg ctgcaagcag ttatcagttg gaagcaacta aagcatttca
     5641 atcaaacata tagcgaactg cgaagaaaag gaaaagtagc gattggtaaa cgacctggga
     5701 aaatccgttc aggcacgatt gttatgctag ctatagacga tcatgatcaa gttttagaag
     5761 tcagaaaaat gcaaggggtt acatctttgg caaaatttca ttcattacct gtctatgcgg
     5821 gtgaagatat ccattacatc gatcgttacc atccctcagt tcgagcggaa gatcgtttga
     5881 cacaagcagc tttagaaaat gccagagaag tatacttacg aatagaggca ggaaatgaaa
     5941 aaagtgaaca accttcattg ccttttattg ctatgctcaa taattttcgg atatggaaaa
     6001 gtacgatcaa agaaaaaagg agtgacaaac gatggatatc ataacaaaat ttgctgaggg
     6061 atttatgagg ctgttccaaa caggtgcaga aacattcata agctggatga caggaatcgt
     6121 accagttgtc ttgatgctga tggttgcaat gaatacgctg attgcttttt taggtgaaga
     6181 ccgagtaacg aaagtagcca aattatcagc gaaaaatccg cttactcgtt accttgtgtt
     6241 accgttctta tctgctttta tgttgggaaa tcctatgtca tttacaatgg ctcgtttcct
     6301 tccagaatac tacaaaccaa gctattatgc tgctcaagct caattttgtc atacgagcaa
     6361 tggtgtattc ccccatatta atcctggaga attgtttgta tggatgggga ttgctcaagg
     6421 gatcgaaacc ttagggctaa attcgatgga gctggctatc cgatacttgc ttgtgggact
     6481 gctgatgaac tttattggtg gttggataac tgattttact actggatttg tatgcagaca
     6541 gcaaggaatc gttcttagca aaaaagtaga gctttcagtt gattagagaa aggagagttt
     6601 taaatgtatg gtgatattaa gatcgtaaga ggaaacggcg ggtatggagg tcctttgatt
     6661 attaggccga caaaagataa acacaagttc atctatgtca caggtggagg tgagaggcca
     6721 atgatcgtag ataaaataga agaactgaca ggtatggagt ctatcaatgg gttcaaaaca
     6781 tcaatacctg atagtgaaat cgcgcttgca atcgttgact gtggagggac tcttagatgt
     6841 ggaatttatc ctaaaaaagg gataccaacc atcaatatcg tttccacagg aaaaagtggc
     6901 ccattagcac aatatatcac tgaagatatt tatgtttcag cagtagggtt agaacaaata
     6961 cagccactaa tggaaactga tgataacaaa gaaacagtaa atactgcatc tccagataaa
     7021 aagtacaaat atgatacttc taaaaagata accgagcaaa aagcagagca gcaaaactgg
     7081 atagcaaaaa ttggaatggg cgcgggaaaa gtagttgcta cattcaatca atcagcaaga
     7141 gaagcagtag atacgatgat ccggacagtg atccctttta tggctttcgt ttcccttttg
     7201 attggtgtga tacaaggttc tgggatcggt aatgtatttg ctaacattat ggcaccttta
     7261 gcaggaaatg cagttggatt aacaatcatt ggctttattt gttcactgcc atttttatct
     7321 cctttgcttg gtccaggggc agttattagc caagtgattg gaacattgat cggtgtagag
     7381 attgggaaag gaaatattcc tccccaatta gcattaccgg cactatttgc tatcaatact
     7441 caaaatgcat gtgattttat tccagtcggt ctaggtttgg aagaagcaaa agctgagaca
     7501 gtagaagtag gtgtaccatc agttctttat tcaagatttc ttaacggcat cccacgagtt
     7561 atcattgctt gggtagcaag ttttggatta tatagctg
//
LOCUS       DADQDV010000101         7580 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.104, whole genome shotgun sequence.
ACCESSION   DADQDV010000101 DADQDV010000000
VERSION     DADQDV010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7580)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7580)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7580
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.104"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..2540)
                     /gene="pglX"
                     /locus_tag="J8S10_002684"
     CDS             complement(<1..2540)
                     /gene="pglX"
                     /locus_tag="J8S10_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BREX-1 system adenine-specific
                     DNA-methyltransferase PglX"
                     /protein_id="HAZ9631243.1"
                     /translation="MDKKAIKNFAVNARRKLIDEVMTKAKRLGIDESKIEDVKKIDSN
                     LQEIEKSGIRIQGKEIAQRNKLIAELKQRASVTSYSEAFQELIEEVAYTWFNRLIAIR
                     FMEVNDYLPDTYRVLSSEISGKIEPDIITDIYDADIFEELSSNEQQQVRTWKTDNSAE
                     AMDKLYQLIFIKICNQLNDYLPELFEEVEDYTELLFTASYIKKDGVIADLLSIPEDDF
                     YVQAGGQVEIIGWLYQYYNSEPHNQVVNIYKGIVKKQDIPAATQLFTTDWVVRYMVDN
                     SLGKYWLDHYPNSELRNKLKYLIPDKYAFEQATSVSNLKPEELKIIDNAMGSGHILVY
                     AFDVLMEIYLTLGYSERDAARAIVEYNLYGLEIDKRAYQLSYFAIMMKGRQYDRLFLK
                     KSLSPNLREFIDSPKVTDEYQERISELNNDKYSERWNEYKELIFDQFENGKELGSIIK
                     LVDKNNQAITKEYLGKVREYISKFNEFTNMDILYGMKEIQEKYLHILDVAEMLVDKYV
                     AVVTNPPYLNKMDKKLKKYVNDNYSDVKKDLFSVFIKLNSQMLIDNGYASFMTPFVWM
                     FISSYEKLRSFLINERNISSLIQMEYSAFEEATVPICTFTIKNSNEQDGSYIKLSDFK
                     GGMEVQKIKTLEAIHQHGECDYFYSTNQDNFKKIPGMPIAYWASDNVITDFAQGKLTN
                     DVADAKQGLATGNNNKFLRYWFEVEFNKIKFDAKTLEDAKKSRKKWFPTTKGGRFRKW
                     YGNNEYVVNWENDGDEIKNYVNENGKLKSRPQNLNYYFKKGITWSTLSSGQVSFRLQN
                     QAIFETKGSVLFSKDITDFEEIFGYVNSKLVNHFLTFISPTLDYHEGP"
     gene            complement(2604..6275)
                     /gene="brxC"
                     /locus_tag="J8S10_002685"
     CDS             complement(2604..6275)
                     /gene="brxC"
                     /locus_tag="J8S10_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BREX system P-loop protein BrxC"
                     /protein_id="HAZ9631244.1"
                     /translation="MLIKDIFAKPIDRNIQGVIKVGQAKDENVQQELEEYVVTKELQK
                     HFKTIFDAYQRSINTPTDKMGVWIQGFFGSGKSHFLKIISYLLANREINDKKAIDYFK
                     EDGKIKDPLTLATMERCSQINTDVILFNIDSKSDAGGKKDKNGIVNVFLKVFNEMQGL
                     STIPHLADFERRLIKEEKFDAFKAAFEEINGAKWQEERHEFDWIQDDIKEAALKIDFM
                     SEAAIDNFLEKASGNYLISIDDFANLVKSYLDSKEADHHIAFLVDEVGQYIGGNRELT
                     LQLQTVVEDLGRICEGKAWVLVTSQEAIDHVTNFDNNSDNDFSKIKDRFATTVSLSSA
                     NADEVIKERILKKKEFANDSLALQFETVQTELKNKLLFVDSPELKLFQDAENYAEVYP
                     FIPYQFNLLGQILTEIRNHSYQGSNLSSGERSLLAMFKEAAERNKENDTTSLVSLDQF
                     YYSLERWIDTAISRVITQATNNSHIQRPTDIDNFNVNVLRILFMIKYVDQAIKPNVEN
                     ITSLMIRNINEDRLETKKRVEEALDLLIKENFVRKNLDSYIFQTDEEQEITREIKNQN
                     ITDSDLIVELSKRIFDGVLDRNSFAYEKLGMSGGNKFKNRYTFTYAQVLDQRPYKQAG
                     NAEMTVNFISPYSDLAGQEAELALKSSRNLLFVELPSDKEFKDDIAMYARMNLYLTTT
                     YSSVVKNFDAIRSEKSGELQELSASINDQLNELLKSAKFFYNGAEIQLTGSDFKAKFQ
                     SALQKMAEEVYHKLNQIDAPKEKEDILYLVKESKNEIIEDPSNEQAVQEIFNFINDQK
                     RNHLTITMKTIRDRFETKQPYGFTELDVEWCIAKLFMSGKIDLLYNNVQISRMDDPNS
                     IVMIIQKRRESEKIKIEPSAVISPKAKKLVDEIGRELFQSRNIVDENNNEHTMENFKK
                     YLKGQLDNLRSYFDLQNTYTYPSAYEYEQIKKYLEVIVQTSDVEDFFYTIKKYRDELF
                     DWAETYDKIKNFHKQNSTQKKIWENAQDKIRLIEKSRRQTSSQEIDQLIHEMKTILKK
                     ADPYSDMMKLNELIQEFIEQYNQLLELESQEILNKLTEEKQATFKLLEGKDFKDQFVP
                     IVDQEFQELKAKIEQANTIDDLVFLSLNVAEQYLIFNQRFDNEENRRRQEEQARKQIE
                     AANLIRETEKDEIDSAAKAEEIAIVKPTIQQKTVPMRTLNVHVKTIKSAADIDELTAE
                     INQKLKEQLQENTEITIQF"
     gene            complement(6300..6875)
                     /locus_tag="J8S10_002686"
     CDS             complement(6300..6875)
                     /locus_tag="J8S10_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1788 domain-containing protein"
                     /protein_id="HAZ9631245.1"
                     /translation="MSLSIQEHLEKLNEVIQKEDFLLNRGLGNEVGYYIFDYDPKDEL
                     IVRDYINDISGTSVGDNYEVKVYNLYVIMLEYLEKRGFTEKAIKMEERRGLQKLVESI
                     GRLLKMDLPEEENVFFEYVDAHTPEKSVVFLTGIGELYPLIRAHSILNKMHQVFDRVP
                     VVMMYPGEYDELSLTILNTNKDDNYYRAFRI"
     gene            complement(6875..7474)
                     /locus_tag="J8S10_002687"
     CDS             complement(6875..7474)
                     /locus_tag="J8S10_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1819 family protein"
                     /protein_id="HAZ9631246.1"
                     /translation="MNKKYSAGLVSKRFWFSEFKLYIQLRLEGYTDIEIKEKNEHENI
                     FFAVSSNRQKEIYQNVKRRVSQLDEAGLQLFNQLNIDNQKLVNLISILMIDDLFNEFM
                     TEVYAENLRKGNLQLTPVDYRSFFTEKRRSSEDISKWKDYTIKRLIAAYQTNLIETGL
                     VRGEKEYGRMTPILLDKRLIQWLVDKNRKDIVLALGGIL"
BASE COUNT         2250 a         1426 c         1007 g         2897 t
ORIGIN      
        1 attggtcctt catggtaatc caaggtggga gaaataaaag ttaaaaagtg attaactaat
       61 ttagagttta catagccaaa tatttcttca aagtcagtta tatcctttga gaacagaaca
      121 gatcctttag tttcaaaaat tgcctgattc tgcaatctaa aagatacttg tccagatgaa
      181 agtgtcgacc aagtaattcc ctttttaaaa tagtaattaa gattttgtgg tctagatttt
      241 aacttcccat tttcattaac ataatttttt atttcatctc catcattctc ccagttaacc
      301 acgtattcat tgtttccata ccattttcta aaacgaccac ctttagttgt aggaaaccat
      361 ttttttctag actttttagc gtcctctaat gttttagcat caaactttat tttgttaaat
      421 tctacttcaa accaataccg caaaaattta ttgttatttc cggttgccaa cccttgtttt
      481 gcatctgcaa catcgttagt taattttcct tgagcaaaat cagtgattac gttatcgctt
      541 gcccagtaag caatcggcat tcctgggatt tttttgaagt tgtcttgatt agtactataa
      601 aaataatcgc attcaccatg ctgatgaatt gcttctaacg ttttaatttt ttgaacttcc
      661 attccacctt taaaatctga taattttata tagcttccat cttgttcatt tgaatttttt
      721 atcgtaaacg tacaaattgg aacggttgct tcttcaaaag ctgaatactc catttgaatc
      781 aaactagaaa tgtttctttc attaattaaa aatgagcgta acttttcata gctagaaatg
      841 aacatccaaa caaatggcgt cataaaggaa gcatatccat tatcaatcag catttggcta
      901 ttcaatttaa taaacacaga aaatagatct tttttgacat cagaatagtt atcatttaca
      961 tattttttta atttcttatc cattttatta agataaggcg gattagtgac taccgctaca
     1021 tatttatcaa ctagcatttc agccacgtca agaatgtgca agtatttttc ttgtatttcc
     1081 ttcatcccat aaagaatatc catattcgta aattcgttga attttgatat atactctctt
     1141 acttttccta agtattcttt agttattgcc tgattatttt tatcgactaa cttaatgatt
     1201 gatccaagtt ctttcccatt ttcaaattga tcaaaaatta actctttgta ttcattccag
     1261 cgttcactat acttatcatt gttcaattca ctaatacgct cttgatactc gtctgtcact
     1321 ttaggagaat caataaactc tcttaaattc ggcgatagac tttttttcaa aaaaagacga
     1381 tcgtattgac gccctttcat cataattgca aaataagaca attgatacgc tcttttatcg
     1441 atttcaagac catataaatt gtattcaacg attgcacgtg cagcatcacg ctcagaatat
     1501 cctaacgtaa gataaatttc catcaataca tcgaaggcgt aaactaaaat atgcccagac
     1561 cccattgcgt tatcgataat ttttagttct tctggtttta aattacttac agatgttgct
     1621 tgttcaaaag catatttatc tggaattaag tatttcaact tatttcttaa ttcactattg
     1681 ggataatgat ctaaccaata ctttcctaaa ctattgtcaa ccatataacg aacgacccaa
     1741 tctgtggtaa atagttgagt tgctgccgga atatcttgtt ttttgacaat ccctttataa
     1801 atattcacca cttgattatg tggctcacta ttatagtact gatacaacca cccaataatc
     1861 tctacctgtc caccagcttg aacatagaaa tcatcctctg gaatacttaa aagatcagcg
     1921 attacaccat cttttttaat ataagaagct gtaaacaaaa gttctgtata atcttctact
     1981 tcttcaaata gctcaggtaa gtaatcattc aattgattac agatttttat aaaaatcaat
     2041 tgatacagct tgtccattgc ttctgctgaa ttatctgttt tccaagttct gacttgttgc
     2101 tgttcattac tagataattc ttcaaagata tcggcatcat aaatatctgt aataatatct
     2161 ggctcaattt tcccacttat ttcactagat aatacacgat acgtgtcagg taaataatca
     2221 tttacctcca taaaccgaat ggcaatcaat cggttaaacc acgtataagc aacctcttcg
     2281 attaactctt gaaaagcttc tgaataagaa gtgacagaag cacgttgttt tagttctgca
     2341 atcaatttgt ttctttgcgc tatttctttt ccttgaattc ttattcctga tttttcgatt
     2401 tcttgtaaat tgctatcaat tttcttcaca tcttcaattt ttgattcatc aattcctaaa
     2461 cgttttgctt tagtcattac ttcatcaatt aattttctac gggcattgac cgcgaaattc
     2521 tttatcgctt tcttatccat ttttctttcc cttctatatg taacctttga aaagacaggc
     2581 acctttttat gcctgtcttt tcactagaat tgaatcgtga tttctgtatt ttcttgaagt
     2641 tgttccttca gtttttgatt aatttcagct gttaactcat caatatctgc tgctgactta
     2701 atagttttaa catgaacgtt aagtgttctc attggtactg ttttctgttg aatagtaggt
     2761 tttactatcg ctatttcttc agcttttgct gcagagtcta tttcatcttt ttcagtttca
     2821 cgaatcaagt ttgctgcttc aatttgttta cgtgcttgtt cttcttgacg tctgcggttt
     2881 tcttcattat cgaaacgttg attaaagatc aaatactgtt ctgctacgtt taatgataag
     2941 aaaacaagat catctatagt attcgcttgt tcaatttttg ctttcagttc ttgaaattct
     3001 tggtcaacta ttggtacaaa ttgatcctta aaatcttttc cttctaataa tttaaatgtt
     3061 gcttgttttt cttccgttaa tttatttaat atttcctgac tttccaactc taacagttga
     3121 ttatattgtt caataaattc ttgaatcaac tcatttagtt tcatcatatc tgaataagga
     3181 tcagcctttt tcaaaatggt tttcatctca tgaatcaatt gatcaatttc ttggctagaa
     3241 gtttgacgcc gacttttttc gattaatcta attttatctt gtgcattctc ccagattttt
     3301 ttctgagtac tattttgctt gtggaaattt ttaattttat catatgtttc agcccagtcg
     3361 aataattcat cgcgatattt tttgattgta taaaaaaagt cttcaacatc tgacgtttga
     3421 acaattactt caagatattt ttttatttgc tcatattcat aagcactagg gtaggtataa
     3481 gtgttttgta aatcaaaata agagcgtaaa ttgtctaatt gaccttttaa atatttcttg
     3541 aaattttcca ttgtatgttc attgttattt tcatcaacaa tattacgact ttgaaacagt
     3601 tctctaccga tttcgtcaac caattttttt gcttttggcg aaatcaccgc gcttggttca
     3661 atttttatct tttcactttc tcgtcgtttt tgaataatca ttacaatact atttggatca
     3721 tccatccgtg aaatttgtac attgttataa agtaaatcaa ttttaccaga catgaaaagt
     3781 ttagcgatgc accattccac atcaagttct gtgaatccat acggttgttt tgtttcaaaa
     3841 cgatcacgaa ttgttttcat cgtaatcgtt aggtgatttc tcttttgatc attgataaaa
     3901 ttgaaaattt cctgaactgc ttgctcattt gatggatctt caataatttc atttttgctt
     3961 tctttcacta aatataagat atcttctttt tctttaggcg catcaatttg gtttaattta
     4021 tggtatactt cttcagccat tttctgaagt gctgattgga attttgcttt aaagtcggag
     4081 cctgtcagtt gaatttctgc accgttatag aaaaattttg cagatttcaa cagttcattt
     4141 aattgatcgt tgatacttgc acttagttcc tgtaattcac cagatttttc cgaacgaatc
     4201 gcgtcaaagt tctttactac actcgaataa gtcgttgtta aataaagatt cattctagca
     4261 tacattgcta tatcatcttt aaattcttta tctgatggca attctacgaa taataagtta
     4321 cgggaactct taagcgcaag ttctgcctct tgacctgcta aatcagagta tggtgaaata
     4381 aaattaactg tcatttcagc atttccagct tgcttgtatg gacgttgatc taacacttgt
     4441 gcataagtaa acgtataccg gtttttaaat ttatttccac ctgacatgcc taatttttca
     4501 taggcaaaac tatttcggtc tagaacgccg tcaaaaattc gtttagatag ttctacgatc
     4561 aaatcactat ctgtaatatt ttgattttta atctcacgag taatttcctg ttcttcatca
     4621 gtttggaaaa tataactatc taagttcttc cgcacaaagt tttccttaat taaaaggtcc
     4681 aatgcttctt ctactcgttt tttagtttcc aggcggtctt cgttgatatt tcttatcatc
     4741 aagctcgtaa tattttcaac atttggtttg atggcttgat caacatattt aatcatgaat
     4801 aaaattcgta agacatttac gttaaagtta tctatatcag ttggtctttg aatatgagaa
     4861 ttatttgtag cttgtgtaat cactcggcta attgctgtat caatccaacg ttctaacgag
     4921 taataaaact gatctaaaga aaccaaactg gttgtatcat tttccttatt tcgttcagcg
     4981 gcttctttaa acattgctag taatgaacgt tcaccagacg ataagtttga tccttgatag
     5041 ctgtgattac gaatctcggt tagaatttgc cccaataaat tgaattgata gggaataaat
     5101 ggataaactt ctgcgtaatt ttcagcatct tggaagagct ttaattcagg actatcaaca
     5161 aagagtaatt tatttttcaa ttctgtttga acagtttcaa attgtaaggc taaagaatca
     5221 ttggcaaact cttttttctt caaaatacgt tctttaatta cttcatcggc atttgctgaa
     5281 gataaactca cagttgtggc aaaacgatcc ttgatcttag aaaaatcatt atcagaattg
     5341 ttatcaaagt ttgttacgtg atcaatcgct tcctgacttg tcactaatac ccaagcctta
     5401 ccttcacaaa ttcgacccaa atcttccaca acggtttgta actgcaaagt caactcacga
     5461 ttaccgccga tatattgtcc gacctcatcg actagaaagg caatatgatg gtctgcttct
     5521 ttggaatcaa gatagctttt aactagattt gcaaagtcat caatgcttat taaataattt
     5581 cctgatgctt tttctaaaaa attatcaata gcggcttcac tcataaaatc gattttaagt
     5641 gccgcttctt tgatatcatc ttggatccaa tcaaactcat ggcgctcttc ttgccatttt
     5701 gccccattaa tctcttcaaa agcagctttg aatgcatcaa acttttcttc tttaattaac
     5761 cgacgttcaa aatctgctag atgtggaatc gtgcttaatc cttgcatttc gttaaatacc
     5821 tttaaaaaaa cattcacgat tccgtttttg tcttttttac cacctgcatc actttttgaa
     5881 tcaatattaa acagaataac atctgtattt atttgtgagc accgttccat cgttgccaaa
     5941 gtcagtggat ctttgatttt cccatcttct ttgaagtaat caatggcttt cttgtcattt
     6001 atttctcgat ttgcgagcaa gtaagaaata atttttaaga aatgagattt acctgaacca
     6061 aagaacccct gaatccaaac acccatttta tctgttggtg tattgatact ccgttggtag
     6121 gcatcaaaaa ttgttttaaa gtgtttttgt agttctttcg taaccacgta ttcttctaat
     6181 tcttgttgaa cattttcatc ctttgcttga ccgaccttaa taactccttg aatatttcgg
     6241 tcaattggtt ttgcaaaaat atctttaatt agcatttaat ctcctacctt ccatcccaac
     6301 taaattctaa atgctcgata ataattatca tctttattgg tattaagaat tgtcaaactt
     6361 aattcatcat attcccctgg atacatcatc acaactggta cgcgatcaaa tacctgatgc
     6421 attttattta aaatagagtg cgctctaatt aatggatata attcgccaat tcctgtcagg
     6481 aacacaactg atttttctgg tgtatgggca tccacatatt caaaaaatac attttcttcc
     6541 tcaggtaaat ccattttcaa taaacgacca atgctttcca ctaatttttg taaaccacgt
     6601 cgttcttcca tcttaatcgc tttttcagtg aaaccgcgtt tttctagata ctctaacata
     6661 atcacataga gattataaac tttcacttca taattatcac caacagatgt tccagatata
     6721 tcattaatat aatctcttac aattaactcg tctttcggat cgtagtcaaa gatataatag
     6781 cctacttcat tacctaaacc acgattcaat aaaaaatctt ctttttgaat tacttcattc
     6841 aacttttcca aatgctcttg aatcgataat gacattataa aattcctccc agtgctagta
     6901 caatatcttt acgattcttg tcaactaacc attgaatcaa tcgtttatct aataatatcg
     6961 gagtcattcg tccatattct ttttcccctc tgactaatcc tgtttcaatt agattcgttt
     7021 gataagcggc aataagccgt ttaatcgtat aatctttcca ttttgaaata tcttctgaac
     7081 ttctccgctt ctctgtaaaa aaagaacggt aatcaactgg tgttaattgc aaatttcctt
     7141 tacgtagatt ttcagcatat acctcagtca taaattcatt aaaaagatca tcaatcataa
     7201 ggatggaaat caaattcact aacttttgat tatctatatt taactgattg aaaagttgca
     7261 atccagcttc atccagttga ctaactctcc ttttcacgtt ctgatagatt tctttttgac
     7321 ggttactgct cactgcaaaa aaaatatttt catgttcatt tttctcttta atttctatat
     7381 ctgtatatcc ttctagtcgt aattgaatat ataacttgaa ctctgaaaac caaaagcgtt
     7441 tagaaactag accagcagaa tattttttat tcaatagatt gcctcctaat catctataat
     7501 tcaataagta aacaagtgtt ttttgctcat cgttagcatt cattttttag tatctactat
     7561 acaatacata tttattatag
//
LOCUS       DADQDV010000102         7446 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.105, whole genome shotgun sequence.
ACCESSION   DADQDV010000102 DADQDV010000000
VERSION     DADQDV010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7446)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7446)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7446
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.105"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..1040
                     /locus_tag="J8S10_002688"
     CDS             <1..1040
                     /locus_tag="J8S10_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631247.1"
                     /translation="IQMKNTIFSDEYVEIIISDHSKNTKEIAKKIEEKKVFDGCHYLE
                     SKSFDDNIGYFQKIKDCLQISCGKSNRYAYYLKNCKSEYFDEFICFSMGEVWLEGIYA
                     CLYRNNKNVQVSILEEGILSYGVDIIPTARTKAIAVLNYLKKRTPLYNKSYNFYCFFP
                     NIYTGRENTIQIPLVTAGSRTALQLSDIFNPMIDIYKEKKYIFFTSVYDFEGGEPVGE
                     YELVCKIADLVGKDNLIVKTHPRDVRTIYKDNGFIEDKNSSIPWEAIQLSGDFNDKIF
                     MTINSGSVISGSTMSAKPVRTYYMYKLCNIEGNPSCKKNAYDIERLLKQKTMKNILKN
                     VKIAESLDDIL"
     gene            1037..2458
                     /locus_tag="J8S10_002689"
     CDS             1037..2458
                     /locus_tag="J8S10_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HAZ9631248.1"
                     /translation="MSKTKYLIKNMGILTISNFSSKILVFLLVPLYTSVLSTTEYGTY
                     DLTISTATLLFPILTLNIVDAVMRFLMDKDKNKKNIASIAIKVIFLSVIVFGSVMYLL
                     NITKLWQDVYGLEKYIFLYYISYVWNQFLIQFAKGLEKVKAMGIAGIISTIVTIIANI
                     FFLLILKWGLIGFFIANILSQIISATYLSVLVRIWEYIDFEAKDPQLKREMLNYSIPL
                     IATVVGWWINSTADRYVVSFIVGVSANGLLSVAYKIPQIINTLQGIFIQAWQISAIKE
                     YGDNETAKFYGNTFVMINLLMCITCSSLIILTRPFSHILYAKDFYEAWKYVPFLLIAN
                     VLNCASGLLGPILSAKKDSKSMMWSAIIGALVNVIMSVVLVYKIGVQGATIATVICSY
                     VIYVVRKRAVGKDIFIKHYHIVVESWGLLFVQAIIEIYFKNYVIEIIIMIILIIINIS
                     YIKQLCYRGRNIISMIKSREHKR"
     gene            2551..3210
                     /locus_tag="J8S10_002690"
     CDS             2551..3210
                     /locus_tag="J8S10_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HAZ9631249.1"
                     /translation="MKIVAIVPMKLNNKRLPQKNTKAFTNGKPLCYYILSTLLKVKQI
                     DKVYVYCSNPDIKEFIPEGVTFLKRSSSLDQDTTSITQVLAGFTKEVEADVYVMTHTT
                     APFISEKSIEKGLDAVLTGEYDSAFAAKKLQDFLWKDGEPFNYELDNIPRTQDLPPLY
                     EETSGFYIYNRNVMTELHRRIGKKPCIVEVGEIESVDIDEAEDFMIADAIYNHLILQG
                     S"
     gene            3229..4812
                     /locus_tag="J8S10_002691"
     CDS             3229..4812
                     /locus_tag="J8S10_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxy-3-methylglutaryl-CoA lyase"
                     /protein_id="HAZ9631250.1"
                     /translation="MNNVQILDCTLRDGGYCNNWEFGFDNTKKIISGLIESGIEIIEC
                     GFLTNKTVYNKNVTKYTTLEELAQIIPEKREGKLFVAMMNYGEYNIEDLPDYDGSSID
                     GIRIAFHKKNCNEALKLCREIKKKGYLVFVQAMVSLNYTDEEFLAVIKNVNQFKPYAF
                     YIVDSFGMMKGKDLTRLFYMIEHNLEKDIQIGFHSHNNMQLAYSNAQKLITVQTNRSL
                     IIDSSVYGMGRGAGNLNTELFVEYLNDNAGKKYQLKPLLYIIDEILNSFYQKSYWGYS
                     LPNYISAVHNAHPNYASYLSYKNTLTIEAMNEIFEMMDEEKKVSYDKQYIEDLYYKYM
                     ETGKIQEEYMEELRKFLSDKKILLIAPGKSSVDEVERIKEFVTKEEVVIISVNFEYSH
                     IDIDYVFLSNLRRFHELPKESRTKCIVTSNIQASDVYLRTSYKKLLSEREVVRDNAGL
                     MAIRFLADMNVDEIFLAGFDGYSHNEDENYGEQSMEIITKFALLDAMNVQMRDELSEL
                     AKKVKVTFLTDPRWVRIDK"
     gene            4947..5525
                     /locus_tag="J8S10_002692"
     CDS             4947..5525
                     /locus_tag="J8S10_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631251.1"
                     /translation="MISILCIVAYHANLRLNYNADGIIVHGSLTANQIFLNYIGIWGQ
                     LGVNCFIFISAYFLSEKRNIHFENVLGIVLECIFYSVLVYGILCACGIETFSLNSFVK
                     EILSFALGRYWFITSYLALYILSPYLNIMLNNLEKLQLQKISMLLFIGVCCYRMLFKT
                     SLFGDCAVLIALYVICYTLKKTIIIFLRDTES"
     gene            5471..5989
                     /locus_tag="J8S10_002693"
     CDS             5471..5989
                     /locus_tag="J8S10_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631252.1"
                     /translation="MLYTEKNDNNIFERHRIIGTIVCITVIPLLISIGILFKFIPNAM
                     VNQMVHIGSPLMVIASIFLFYVFKNFSFYSKYINKLARTSLGVYILHENHYFIDGMKS
                     RGLIWDGIFGLGKRFLDRDFWIWFIIAVVVVCIICMAIDVVREKFERQIFKIKSVKNL
                     CKLMNHVINIYP"
     gene            5997..7037
                     /locus_tag="J8S10_002694"
     CDS             5997..7037
                     /locus_tag="J8S10_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HAZ9631253.1"
                     /translation="MRRKEVKVISFGELLLRLAAPGYSKLFQRDSLETTFCGGEANVA
                     VSLAIFGYQSEFITKLPDSDVGYAAANALRYFGVNVDNIIFGEGRMGLYYLEKGAAQR
                     PSKVIYDRKFSAISLADSDEFKWKEILNDANWFHWTGINPALSENLFETSLDACQAAK
                     KRGITISCDLNYRSKLWTSEEAKEKMEQILPLVDICICNEEDAEKVLGIKAEHTNINS
                     GELNKDGYVQVAREIHKKFGCRYVATTLRRSYSASRNGWSAMLYEAEKDKAYFSTEYN
                     IQIVDRVGGGDSFSAGIIYALCENMSGQKAIEFATASSCLKHTIEGDFNRTTIEDVYN
                     LMNSGGNGRVLR"
     gene            7286..>7446
                     /locus_tag="J8S10_002695"
     CDS             7286..>7446
                     /locus_tag="J8S10_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAZ9631254.1"
                     /translation="MTYTYLTTDELVIIESYLKINQSVAKTAHCLNRSSQTIHKVYLF
                     FKQRKSALE"
BASE COUNT         2730 a          852 c         1405 g         2459 t
ORIGIN      
        1 caatacaaat gaaaaataca attttttccg atgagtatgt tgaaattatt atttctgatc
       61 attctaaaaa cactaaagaa attgcgaaaa aaatagaaga aaaaaaagtg tttgatggct
      121 gtcattattt agaaagcaaa tcttttgatg ataatattgg gtattttcaa aagattaagg
      181 actgtcttca gatttcttgt ggtaaatcaa atcgatatgc ctattatttg aaaaactgta
      241 aaagtgaata ttttgatgaa tttatttgtt tttcaatggg agaggtttgg ttggaaggaa
      301 tatatgcttg cttatatcga aataataaaa atgtacaggt atcaatttta gaagaaggta
      361 ttttaagcta tggagttgac attattccaa cagcaagaac aaaagctatc gcagtactca
      421 attacttaaa aaaaaggact ccactatata acaaaagcta taatttttat tgtttttttc
      481 ctaatatata tacaggaaga gagaatacaa tacaaattcc attagttaca gctgggtcaa
      541 gaaccgcatt gcaactttcg gatattttta accctatgat agatatttat aaagaaaaaa
      601 aatatatatt ttttacgtct gtttatgatt ttgagggcgg agaacctgtc ggagaatatg
      661 aattagtatg caaaatagca gacttagtag gaaaagataa tctaattgtt aagacgcatc
      721 ctagagatgt aagaacaatt tataaagata atggatttat cgaggataaa aattcatcaa
      781 taccttggga ggcgattcaa ttgtcaggcg attttaacga taaaatattt atgacaatta
      841 attcaggaag tgttatttca ggtagtacaa tgtctgcaaa acctgtacgc acgtattata
      901 tgtataaatt gtgtaacata gaaggaaatc cgtcttgcaa aaagaatgcg tatgatattg
      961 agcgattgct taagcaaaaa acgatgaaaa acattttaaa gaatgtgaaa atagcagaaa
     1021 gcttagatga tatactatga gcaaaactaa atatttaatt aaaaatatgg gaatattaac
     1081 aataagtaat ttttcttcaa aaattttagt ttttttgtta gtccctttat atacaagtgt
     1141 attatccaca acagaatatg gcacatatga tttgacaatt tcaacagcca cattattgtt
     1201 tccaatttta accttaaaca ttgtagatgc tgtgatgcgc tttttaatgg ataaagataa
     1261 aaataaaaaa aatatagcat ctatagcgat taaagttata tttttaagcg tgatagtctt
     1321 tggatccgta atgtatttgt taaatattac aaaattatgg caagatgttt atggattaga
     1381 aaaatatatt tttttgtatt atatatccta tgtatggaat caatttctaa tacaatttgc
     1441 taaagggtta gaaaaagtta aagctatggg catagcaggt attatcagca caattgtaac
     1501 aataattgcc aatattttct tcttgcttat tctgaaatgg ggattaattg gttttttcat
     1561 tgcaaatatt ttatcacaga ttatttcagc tacttatctg tcagtattag tgagaatatg
     1621 ggaatatatc gattttgagg ctaaagatcc tcagctaaag agagaaatgc taaattactc
     1681 gattccatta attgcaactg ttgttggatg gtggattaat agtacagctg ataggtatgt
     1741 ggtttccttt atagtaggtg tctcggcgaa tggcttattg tctgtggcat ataaaatacc
     1801 tcaaataatt aatactttgc agggaatatt tatacaggcc tggcaaattt ctgcaattaa
     1861 agaatatgga gataatgaga ctgcaaaatt ttatggaaat acatttgtta tgattaattt
     1921 gttaatgtgc ataacctgtt caagtcttat catattaact agaccgtttt cacatattct
     1981 ttatgcgaaa gacttttatg aagcgtggaa atatgttcca tttttattaa tagctaatgt
     2041 tttaaattgt gcatcaggtc tgttaggacc tatcttatca gcaaaaaaag attctaaatc
     2101 catgatgtgg tctgcaatca taggggcatt agttaatgtg attatgagtg tagtccttgt
     2161 ttataagata ggggttcaag gtgccacaat agccactgtt atatgttcat atgtaatata
     2221 tgttgttcgt aaacgagctg tgggaaaaga tatttttata aagcattatc atattgttgt
     2281 ggaatcttgg ggattattgt ttgttcaggc aatcatagaa atatatttta aaaattatgt
     2341 aatagaaatt ataattatga ttattttaat tattataaat atcagttata ttaagcagtt
     2401 gtgttataga ggaagaaaca ttatttcaat gattaagagt cgagagcaca aacggtagac
     2461 gatgttattt ttataaaaag atataattta ttaatggtcg ataattatga aaggaaaaat
     2521 attcttaaaa aaaagagtat aggatgtcgt atgaaaatag tcgctatagt accaatgaag
     2581 ttaaataaca aaagattgcc acaaaaaaac acgaaagctt ttaccaatgg aaaaccattg
     2641 tgttattata tactttcaac acttttaaaa gtaaaacaga ttgataaagt gtatgtctat
     2701 tgtagtaacc cagatattaa agaatttata ccagaaggtg taacattttt aaagagatct
     2761 agttccttag atcaggatac aacgagtatt acacaggtat tagccggttt cacaaaagaa
     2821 gtagaggctg atgtatatgt aatgacacac acaacagcac catttattag cgaaaaatct
     2881 attgaaaaag gactagatgc cgtgctgaca ggagaatatg attctgcatt tgctgcaaaa
     2941 aaattgcaag atttcttatg gaaagacggt gaaccattta attatgaatt ggacaatatt
     3001 cctagaacac aggatttgcc gcctttatac gaagaaacta gtggatttta tatttataat
     3061 cgcaatgtga tgaccgagtt gcatagaaga attgggaaaa aaccttgcat agttgaagta
     3121 ggtgagattg agtcagttga tattgatgaa gccgaggatt ttatgattgc tgatgcgatt
     3181 tataatcatc ttattttaca aggtagttaa gacaggggga aggttaggat gaacaatgta
     3241 cagattttag attgcacact tagagatggg ggctattgta acaattggga atttggattt
     3301 gataatacaa aaaaaattat ttctggactt atagaatcag gaattgagat tatagaatgt
     3361 gggtttctca caaataaaac agtatacaat aaaaatgtta caaaatatac gaccttagaa
     3421 gaattagcac agataattcc tgaaaaaaga gaaggaaaat tatttgtagc aatgatgaac
     3481 tatggcgaat ataatataga ggatcttcca gattatgatg gttcatctat tgatggaatt
     3541 aggattgcgt ttcataaaaa aaattgcaat gaagcgttga aattatgtcg tgagataaag
     3601 aaaaaaggct acttagtttt tgttcaagct atggtatctc tcaattatac agatgaagag
     3661 tttttagcag taataaaaaa tgtgaatcag tttaaaccat acgcttttta tattgttgat
     3721 agttttggaa tgatgaaagg aaaagattta actcgtcttt tttacatgat tgagcataat
     3781 ctagaaaaag atatacagat aggttttcac tcacataata acatgcagct tgcatattct
     3841 aatgcacaaa aacttataac cgtacaaaca aatcgaagcc tgattattga ttcttcggtg
     3901 tacggaatgg gaagaggagc aggtaatctt aacacagaac tatttgtaga atatttgaat
     3961 gataatgcag gaaaaaaata tcaattaaaa ccattattat atataattga tgaaatacta
     4021 aatagtttct atcagaagag ttattgggga tattcattac caaactatat ttcagcagtt
     4081 cataatgctc atcctaatta tgcaagctat ctgtcatata agaatacttt aacaattgaa
     4141 gcaatgaatg aaatattcga aatgatggat gaagaaaaaa aggtatctta tgataaacaa
     4201 tatatagaag atttatacta caaatatatg gaaactggga aaatacagga ggaatatatg
     4261 gaagaactga gaaaatttct ctcagacaaa aaaattctac tgattgcacc aggaaaaagt
     4321 tctgtagatg aggtagaaag aataaaagag tttgttacca aagaagaagt cgtaataatt
     4381 agtgtaaatt ttgaatattc tcatatagat atagattacg tatttttaag taatttaaga
     4441 cgttttcatg aattaccgaa agaaagcaga actaaatgta ttgttacatc aaatatacaa
     4501 gcatcggatg tatatttacg gacgagttat aaaaagttgt tatctgaaag ggaagttgta
     4561 agagacaatg caggattaat ggcaattaga tttttagccg atatgaatgt ggatgaaata
     4621 ttcttagctg gatttgatgg atattcacat aatgaagatg agaattatgg tgagcaatcc
     4681 atggaaatta taacaaaatt tgcattatta gatgcaatga acgtgcaaat gagagatgaa
     4741 ttgtcagaat tagctaaaaa agtaaaggtg acatttttaa cggatccacg ttgggttcga
     4801 attgataagt agtagtaata atgtttttaa aattttgata aagagatagt gagagaataa
     4861 aaatgggtaa agtcttaaat aaaaaagaag aaaaatattt aagggccgat ggggcgagat
     4921 gaaactctaa ttttgaactt ttaagaatca tttctatatt gtgtattgtt gcttaccatg
     4981 ctaatttgcg tttaaattat aatgcagacg gaattatagt acatggttca ttaactgcta
     5041 accagatttt cttgaattat attggtattt ggggtcagct aggagttaat tgttttatat
     5101 ttatttcggc atatttttta agtgagaaaa gaaacattca ctttgaaaat gttttgggaa
     5161 ttgtattaga atgtattttt tatagtgtat tagtttatgg aattctttgt gcatgtggaa
     5221 tagaaacatt ttcattgaac agctttgtaa aagaaatatt atcatttgct ctaggtagat
     5281 attggtttat tacatcctat ttagcattgt atattctaag tccgtattta aatatcatgc
     5341 ttaacaatct ggaaaaactt cagttgcaaa aaataagtat gttattgttt ataggtgtat
     5401 gctgttatcg tatgttattt aaaacatctt tgtttgggga ttgtgctgtt ttaattgcac
     5461 tatatgtcat atgttataca ctgaaaaaaa cgataataat atttttgaga gacacagaat
     5521 cataggaaca attgtatgta taacagttat accacttctc atatccatag gaatactttt
     5581 caaatttata ccaaatgcaa tggttaacca gatggttcat attggttctc cattgatggt
     5641 tatagcaagt atatttttat tttatgtatt taaaaatttt tcattttaca gtaagtatat
     5701 aaataaactt gcgagaacca gtttaggggt atatatttta catgaaaatc attatttcat
     5761 tgatggtatg aagtctagag gcttaatatg ggatgggata tttggattag gcaaaaggtt
     5821 tttagatagg gatttttgga tttggtttat aattgcagtt gtagttgtgt gcataatttg
     5881 catggctatc gatgttgtaa gagaaaaatt tgaaagacag atttttaaaa ttaagagtgt
     5941 aaagaacctg tgtaaactta tgaatcatgt tataaatata tacccataat taataaatga
     6001 ggagaaaaga agtgaaagtt atatcattcg gagaattatt attgagactt gcagcacccg
     6061 gttattcaaa gttatttcaa agagatagtt tggagactac attctgcgga ggggaagcta
     6121 atgtagcggt atccttagca atatttggat atcaatcaga atttataaca aagcttccgg
     6181 attcagatgt tggatatgcg gcagctaatg ctttgcgtta ttttggagta aatgttgata
     6241 atattatatt tggagaggga cgcatgggac tgtattattt agaaaaagga gcagctcaga
     6301 gaccatctaa agtaatttat gacagaaaat tttctgcaat ttcgttagct gatagtgatg
     6361 aatttaagtg gaaggagatc ctaaacgatg caaattggtt tcattggaca gggataaatc
     6421 cagcattgtc tgagaatctc tttgagacgt ccttagatgc atgtcaggct gccaaaaaaa
     6481 gaggtataac aatttcttgt gatttaaatt atcgatccaa gctttggaca tcagaggaag
     6541 caaaagaaaa gatggaacag atactaccat tggttgatat ttgtatttgt aatgaagaag
     6601 atgcagaaaa agtgctagga attaaagctg agcatacaaa tattaatagt ggagaattaa
     6661 ataaagatgg ctatgtgcag gtggctaggg agattcacaa gaagtttgga tgtaggtatg
     6721 tagctacaac tctgcgtaga agttattcgg caagtagaaa tggttggagt gcaatgttat
     6781 acgaagcaga aaaagataaa gcgtattttt ccacagaata caacatacaa attgttgatc
     6841 gcgttggtgg tggagacagc ttttctgctg gtataatata tgcgttatgt gaaaatatgt
     6901 ccggacaaaa ggctattgaa tttgcgactg catctagttg tttaaaacat actatagaag
     6961 gtgattttaa tcgaactaca attgaggatg tatataattt aatgaatagc ggtggaaatg
     7021 gtcgcgtgtt gcgttagtca acatataaag ataaatcaca gtaattttta tggtgattat
     7081 ctgtcttagt agtgattaga ataacgtgaa aataaattgt tgagcgttta tactgttttg
     7141 aaaaataaat ttaacatatt gaaaaataca aatatatacg tatattataa agcgccgatt
     7201 gtaaaattaa gctagacaac taaaacagtc atttgtgcta cactcaaaat agttccgacc
     7261 aaagaattat aaggagtgag tgcaaataac ctatacctat cttacaacgg atgaacttgt
     7321 aataatagag tcttatttga aaattaacca atctgttgct aaaactgcgc attgcttgaa
     7381 tcgttcaagt caaacgatcc ataaagtata tctgttcttc aagcaaagaa aatcagcctt
     7441 agaata
//
LOCUS       DADQDV010000103         7357 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.106, whole genome shotgun sequence.
ACCESSION   DADQDV010000103 DADQDV010000000
VERSION     DADQDV010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7357
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.106"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(204..1652)
                     /gene="cls"
                     /locus_tag="J8S10_002696"
     CDS             complement(204..1652)
                     /gene="cls"
                     /locus_tag="J8S10_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HAZ9631255.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGEIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHTTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLVYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            complement(1804..2697)
                     /locus_tag="J8S10_002697"
     CDS             complement(1804..2697)
                     /locus_tag="J8S10_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9631256.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            complement(2681..3367)
                     /gene="ftsE"
                     /locus_tag="J8S10_002698"
     CDS             complement(2681..3367)
                     /gene="ftsE"
                     /locus_tag="J8S10_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HAZ9631257.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            complement(3472..4573)
                     /gene="prfB"
                     /locus_tag="J8S10_002699"
     CDS             complement(join(3472..4509,4511..4573))
                     /gene="prfB"
                     /locus_tag="J8S10_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078989099.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HAZ9631258.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRGLFDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            complement(4699..7233)
                     /gene="secA"
                     /locus_tag="J8S10_002700"
     CDS             complement(4699..7233)
                     /gene="secA"
                     /locus_tag="J8S10_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HAZ9631259.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
BASE COUNT         1962 a         1634 c         1284 g         2477 t
ORIGIN      
        1 gctatactgg ctttgaaatg tgtctctttt aatagcatat attagcttat ttcttgcttt
       61 ccccaaaaaa caagagatac cccaaagtta atttcgctca tgcgagacgc tttctccatt
      121 tctgacgtac tctcagaaat ggccccgtta aaaaaggaca cgagatctcc atctgttgat
      181 ggttctcatg tcctttttat gttttaaagg agcggcgaaa tcaatcttgc taatccttct
      241 ttcatcttga tgattattcc tcggttttca tacatttctt ttgtgagatg cgtagaaatt
      301 ttcgagtctt caaaaaaagc ttttcttaca cgtgaagcca ttcgttcatc ataaaccagt
      361 gtattgacct caaagtccaa gcgaaatgaa cgaacatcga tatttgctga gccaactgaa
      421 acaatgccac catcgataat catcgtcttt gcatgaataa atccattctc atatgtttcg
      481 atccttgctc catactcgat cagctctgca gcgaaagaat acgttgccca gtaaacgaga
      541 agatgatctg gtttgttagg tatttggata tgaactttta cgcctgaaag aagagccaac
      601 ttcagtgctt catgaatcga tccatccggt atgtaataag gcgtttggat caatatctcc
      661 cgtttggcta acgaaatcat tttcaaataa gtcattttga tttgttcatg ttcggtatct
      721 ggtccgcttg tcacgatttg aacagctata tcaccagtag tgtgaatgga cggaaaaaat
      781 ttgggagaat agcctacttc ttttgtatgc tgagaattcc agtccatcaa aaaacggttt
      841 tgcaaggtat acaccgcttc tccgtaaata cgcaaatgat tgtctcgcca ataaccaaat
      901 ttctttacca atcctagata ttcatttcca acattgaacc cacctgtata tccgatttcc
      961 ccatcaataa ctacgatttt acgatgattg cgataattga tccgaggatt aatatacgga
     1021 acaaatagag gaaagaaaaa tgcgacttct ccgcctgctt ttttcaaatt ctgaaaaaag
     1081 ctggaagaaa cttgtgtgga accccatgca tcaagaagga ctctgacttt tacccctcgt
     1141 cttgccgcct ctgtcaatgc atctcgaact tcttcaccta atgcatcact gcgataaata
     1201 taatactgga agtggatatg gtcttctgcc tgcttgatat cttcaatcag cgcatcgaat
     1261 ttttcacgac catctgtaaa taaagtgatt tcatttttag tcgtatagag cgtactttca
     1321 aataccgtga gcatatagat caattgtttc acatctactt gtccagtagg cggatgagga
     1381 taaagccctc gcatcaatgc ctgtttgtct tcttcaattt ccaggttctt accgattttc
     1441 ccttggatct tcaaatcaaa gattttctct ttggaaatcc ctcttcctaa aaaaatatat
     1501 aaaataaatc ctacaactgg aatgaacatc aaaacgagca gccatgccca tgtttgagca
     1561 gtttcctttc tttctcgaaa aacgatgata aaggaaagca aaatattcat aatcaaaagg
     1621 atcgtaaaaa aattgtcaac gataattttc acggcttcac ctcttcttct accaacttaa
     1681 gaatacccaa gttgtttttt aaagtaaagg gaaaaaagcc gcttccttct attctcctag
     1741 ccaataaaaa aagaaagctg gaacgaaact gtccaacttt ctcattttat ttatattgtg
     1801 gtattagaat ttcaagaaac gtctcataga aatgatcgag ccaagtgaac caatgatcac
     1861 accaatgccg accattaaaa gattgatttt ccaaacgata ttttgtggat gaatcaatga
     1921 ataatgggaa cgtaataatg atggattgat caattggaaa aaccatgcat aaccaaatgt
     1981 gatgatcaaa attggaagaa ttgcaccgat cagaccgatc cagccacctt caaggaaaaa
     2041 cggccagcga atatatccat tttttgcacc gactaaacgc atgatttgaa tttcacgctg
     2101 tctagacaaa atcgtgatcc gaatcgtgtt cgaaatgaga aacatcgcta cgaacagcag
     2161 caatgccgct gcaactaatc cccatgtccg aactgcacca gcgatttgga aaatccgatc
     2221 tgaggaagct ccaccgtaat cagaacgaga aacattcttc aaatctgctg cttcttctgc
     2281 tacttgtttt gtataagaag gatcagtagc acttactaca tacacatcat ataacgggtt
     2341 attgtcacct tcaaacaatt tccaggaatc acccatttcg ttttggattt ttttcaattc
     2401 ctgttctttg cttgaaaatt caactttttt aacatgatct aagtcattca attctttttc
     2461 tagctttttc atctcttcgt cttttgtacc gatatctacg aatacagata catcaacgtt
     2521 tccttctata tcctgagcta atttagttgc attcatgata actgccatga atacaccgac
     2581 taaagtcaac gtgatcgtta ccgcactgac tgaagcaact gtcatccagc cgttacgttt
     2641 caaactcttg atactttcta ataaatggcg gaaaaaggtt ctaatcatcg tatccatatt
     2701 ccccttccgc ttgatctcga ataatgcggc cgttttcgat agcaattact cggtgccgaa
     2761 tcgtatttac gatcgtactg ttatgtgtag ccatcacgac agtagttcct tgggcattga
     2821 tccgatctaa taatttcatg atttcccatg agttttctgg atccagattt cctgtcggtt
     2881 catccgcgat aagtacttta ggcgtattca cgattgcccg agcaatagag acacgttgct
     2941 gttccccacc ggataattcg ctaggaaaga ctcgaacttt gtgtttcaaa ccaacaaggt
     3001 ccagcacttc cattactcgt tttttgatat ctcgaggttt tctgccgata acttgcatag
     3061 cgtacgcaac attttcatat actgtttttc ttggtaataa tttatagtct tggaacacca
     3121 cgccgatttc tctgcgtaga taaggaactt cgcggttttt gattgctatt agatcatgac
     3181 ctgcgacgtt caaagttcct tttgaagctt tttcttctcg atacatcaat ttgatgaatg
     3241 tagatttacc ggctccagac ggaccaacca catagacaaa ctctccttgt tcgatgacaa
     3301 tcgagagatt gcggatagcg gtcgtaccat ttgagtactt cttcattaca tccttcattt
     3361 caatcatggc gttctctcca tatctttttc agtctttagc tattatagca tggcaatgtt
     3421 tcaacatgct tgcaaaatct tacaatttta tttcaattta acaatgggtt cttattgtag
     3481 atgcattttt aaatagccgt caataaataa atcaaggtca ccgtccataa ctgcttggac
     3541 atttcctgtc tctacgtttg tccgatggtc ttttaccata gaatagggat ggaaaacata
     3601 agaacggatc tgtgaacccc agccgatttc tttttgttct cctcgaagtg cagctgcttc
     3661 ttgttctttc ttttccactt ctaattgata aagcttagct tttaacatcc ccatcgcttg
     3721 ctcacggttt ttcaattgtg agcgttgtgc ctgactagct actactgttc ctgtaggcaa
     3781 gtgagtgatc cgtacagcag attctgtttt attgatgtgc tgaccacctg caccacttgc
     3841 tcggtacgta tcgattttca aatcatctgg attgatttct atatcgatcg tttcatcaag
     3901 ctctggcatc acatctaccg aacaaaaaga agtatgacgt cgtttcgctg agtcaaaagg
     3961 cgaaatccgt acaaggcgat gaacaccttt ttctgatttt agataaccaa aagcgttatg
     4021 tcctttaatc agcagggtca cactcttgat ccctgcttca tcacctgctt gataatctag
     4081 tgtttctact tgatagccat gctgctctgc ccaacgtgta tacatacgta aaagcatgct
     4141 gccccagtct tgggactccg ttccgccagc ccctggatgc aattcgacga tcgcattgtt
     4201 tcgatcataa ggtccgtcta acagcataga taattcatac gtcttcattt tttcatctaa
     4261 tgcattgata cgtgtttctg cttcttcttg cattgctgca tcaggttctt cttgcagcat
     4321 ctccaccatc aattcgattt cttctagttc ttcggcaaga gaatggaatt ggtcataggt
     4381 ttctttatta gcgttatttt cgctgatcac tttttgtgcg gcttcgctgt catcccaaaa
     4441 accaggttca gccatttttg cttctgcttc cgcgatgtct tcttccagct gatctaagtc
     4501 aaagagacct cctgaaactt gtgacctttt cctgcatttc tgtcaggaga tttcgaattt
     4561 cggatatttc catgtttttt ccttctttca ctatactttt ttcattatat ctagtctaac
     4621 agaatcagca aataacagaa agaaggtgag acgaattctt aaaaaaagaa tttgtctcac
     4681 caatcctgct gtcagaaatt agtttgcatt ttttccatga cagttcttat attttttccc
     4741 gcttccacaa ggacaaggat catttcttcc gaccttattc acatggattg gctgtttttt
     4801 cgcgctagta ttactatttt ctttggcatc tccgtcttct gagtgagaag ctgttccttg
     4861 agaaacctgt tcacgctgta cgttttgacg gatctcagct ttcataaaga ttcgagtgac
     4921 ttcatactcg atggcgccta ccatatcttc aaacatctta tagccttctg tttgatattc
     4981 gactaatgga ttgttctgtc cataagcacg taagccgatt gactgacgta attgatccat
     5041 tgcatcaata tggtctgtcc atttagagtc cacaacacgc aagatcacga ctttttcaaa
     5101 ttccaacagt tgctctggac catttagttg agccgctttg gtattaaata cttcttgtgc
     5161 tcgttcgttt agatactctt tgatctcctg agctgttttt ccttcgatat ctgcaagagt
     5221 aatgctatct tcatggacaa gagtactgcc ggcaaaatcg atgatacttt ccaaattcca
     5281 attttctttc tctaattgtg tatgcgcatc tactacacga ctgattgtcc gtttgaccat
     5341 gttcattagt ggcttggata agcttttttc ttccatgatt acttcttgtc gctgtttata
     5401 gattacttca cgttgttcac gcatcacatc atcgtattgt aagacgtttt tacgtgtgtc
     5461 atagttattt ccttctacac gtttttgtgc agattctact tgtttcgtca gcatcttgct
     5521 ttggataaca gcatcttcct caccgatctt catccgatct aagaaagctt tgattcgttc
     5581 tgaaccgaat cgtttcatca aatcatcttc caatgacaag tagaactgtg acataccagg
     5641 gtctccttga cgtcctgcac gtcctcgaag ctggttatcg atacgacgag attcatgtcg
     5701 ttctgtcccg ataactgcta gaccaccaag ttctcttacc ccaagtccta acttgatatc
     5761 tgttccccga ccagccatgt tggtagcaat cgtcacagca cctttttgac cagcattcat
     5821 gatgatctct gcttctttaa agtgattttt cgcattcagc acttcatgag gaatacgttc
     5881 ttgattcagc atatctgata ataactcaga tgtttcaacc gcaacagttc cgactaacac
     5941 aggttgacct ttgcggtagc gatctttgat atcttgcacg acagcgtgga acttgctttg
     6001 taatgttggg taaagcaaat ctggacgatc atcacggata accggacgat ttgtcggaat
     6061 ctggtatact tggatgttat aaatttctct gaattcttct tcttctgttt tagctgtacc
     6121 agtcattccc gcaagtttct tgtacatacg gaaatagttc tggaaagtga tcgtcgccat
     6181 ggttttcgtt tcgtcttcga tctctacgcc ttctttagct tcgattgctt ggtgaagtcc
     6241 atctgaataa cggcgtccat ccatgatccg accagtgaac tggtcaacaa tcagtacttt
     6301 tccgtcttgg acaacataat cgatatctaa aagcatgata tagttggctc tcaatgcttg
     6361 atccaagtga tgggtcaatg cagtattttc aatgtcgtat aagttatcca aaccgaatgt
     6421 ttcttctgct ttttcgatcc ctgcttcggt taaactgatt gtttttgatt gtacatcgat
     6481 tttataatct tcttcttctt tcaaacgttt cacgaagttg tctgctcttg tatataaagc
     6541 tgtggatttt tctgcttgcc ctgaaatgat cagcggcgtt ctcgcttcat caatcaagat
     6601 tgagtcaact tcatcgacaa tggcataatt cagcggacgt tgtaccattt gatggcggta
     6661 aacgaccata ttgtctctca agtagtcaaa tcctaattca ttattcgtac tataagtgat
     6721 atcacaatta taagcctcgc gtttttcatc cgaagatttt gagttgatat tcaaccccac
     6781 tgttaatcct aagaaattat aaagttcgcc catttccgtc gagtcacggg ttgctaaata
     6841 ttcattgacg gtaactacgt gtaccccttc gccagtcaga gcatttagat atactggcat
     6901 cgttgcggtc aaggttttac cttcaccagt acgcatttca gggatatttc catcgtgaag
     6961 cacgattcca cccatcaatt gtacgtggta tggatataaa cctaatacac gttttgctgc
     7021 ttctcggacg actgcaaaag cttccggaag taattgatct aatgtttctc ctttttggta
     7081 tctgcccttg aattcagcag tttttgcctg taattgttca tcagttaatg ctgccatttg
     7141 gtcagcgtat gcttcaactt tttttgcaat gctatctaaa cgttttagtt ctttcttatc
     7201 gttttcgata agtgaacgaa tcaaattggc catgcgttgt gtaatctcct tttccttctg
     7261 tgtattatcc agactatgta gactttactt ttcattttat cattagttat agataattga
     7321 aatatcttaa gcgtattaaa gtaagaactt cataatt
//
LOCUS       DADQDV010000104         7183 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.107, whole genome shotgun sequence.
ACCESSION   DADQDV010000104 DADQDV010000000
VERSION     DADQDV010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7183)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7183)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7183
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.107"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(1155..1553)
                     /locus_tag="J8S10_002701"
     CDS             complement(1155..1553)
                     /locus_tag="J8S10_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631260.1"
                     /translation="MRLRRNKNYTTIILEDFTDQELLIVGKTKADFIEKGNASIVKAS
                     KVAVEKYFDSLEESAKEIFNGEKAGSYELDGIKFSLIPTTENIIPKKLYYIFSSEKHT
                     SMKPCIFDWQWLIDAVLDVKCSKYNITLGC"
     gene            1769..2824
                     /locus_tag="J8S10_002702"
     CDS             1769..2824
                     /locus_tag="J8S10_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParM/StbA family protein"
                     /protein_id="HAZ9631261.1"
                     /translation="MKEPLLFSVDLGNKSVKEMSTHVSPLSLPSRILNKNIINSGRFS
                     NIGSSLKRSLNVSEYSLVNTTESYYFGKDIHELGKDDYVIESLGFGISRYKQETYQDI
                     LSFSLANLARLEDQSDDVLTVNLVLGLPSSDYTETIVKYVMQQATRQHSVEVDGKAYN
                     INVDTVWVLPQPIGTLYNLLLADDGSVQDESLISQKIGFVDIGGGTKLFDVVQNFEID
                     ENNREQKDTGIFTLYNRIVNMLDLPISPNAFQLEKIIREGKEKGVYLFKPSGNESFDI
                     SEVVEREIKTYTNMVVAEVLATFKNFTTLDKVVFTGGGASIIDKQLVKDKIPHTLFVE
                     DSEFSNVKGFYKFGLTQ"
     gene            2844..3197
                     /locus_tag="J8S10_002703"
     CDS             2844..3197
                     /locus_tag="J8S10_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631262.1"
                     /translation="MNKGKSERYVVIINREKVSELPLAEFLESEYETLGVKYSQTIKK
                     ALNLYRRVKNNEVTIIEAGNDRNDSKVAEVKNKPTDHNPIQQAHPSTVTSDHSAKKEK
                     PMLKGFNAPSNKDLL"
     gene            complement(3379..3675)
                     /locus_tag="J8S10_002704"
     CDS             complement(3379..3675)
                     /locus_tag="J8S10_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631263.1"
                     /translation="MIEVKENRFKKFAEAEVEEVPEVVEAVEEPKQTPKETTSSLVAK
                     LKSDSSEKKKNYQFTLQPSQRKKLSKISEKLGIRSDSALLGEMIDNLYDEVFGE"
     gene            complement(3679..4497)
                     /locus_tag="J8S10_002705"
     CDS             complement(3679..4497)
                     /locus_tag="J8S10_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAZ9631264.1"
                     /translation="MEKKLSIITGNIEKGGTGKTTTIYNLGGYAVENLGMKVLYIDED
                     KSQNLSKRFPDAFSKAKRENTINHLYLHGSAEPLAINENMDILVAGEDLKQVEMQMRD
                     MPNNRTLLFRWIVVNYEQLKEKYDLILIDTHNDAGLLAQNAWAVSDLVVGISDPSKDG
                     FEALLKLGKDIDALAKQLIDIKTGETLMETKYATIGSRIKHNTNSSREFLELVPTLSN
                     YLGYVQEKELLNATSLEGKNIAEFAKDKNIYRKNKDFFESTFTLYNKIIDTAQE"
     gene            4723..4944
                     /locus_tag="J8S10_002706"
     CDS             4723..4944
                     /locus_tag="J8S10_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1778 domain-containing protein"
                     /protein_id="HAZ9631265.1"
                     /translation="MPVISIRVSKEEKDFLEKVAEFNGDNISEFMRSNSLQTAETLVD
                     FATYKQLMKEHEENDQSISHEDMLKELGL"
     gene            4946..5212
                     /locus_tag="J8S10_002707"
     CDS             4946..5212
                     /locus_tag="J8S10_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAZ9631266.1"
                     /translation="MTYQVRYEREAQKALKKMDKFQAKVILNWIEKNLVGTDDPRKHG
                     KGLTANKSGYWRYRVGAYRIIADISEHEVTILILSIGHRSEVYK"
     gene            5325..5864
                     /locus_tag="J8S10_002708"
     CDS             5325..5864
                     /locus_tag="J8S10_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631267.1"
                     /translation="MYNISVNKLINFQKERFFMGWYGDYSSANEVIEEKKGYAKNGLE
                     IVGTKVTKTYGIILFKDAEGTYDIDSFIFRDEMYKPIYFLNDSPAYFKKIPKKWLKFF
                     VGDQEKMVKLQLDRIKEESNKPKLDDLLVAGKTYSIWDGSYVAVYQYKLKRSFIFRLQ
                     DGSLTRFTRLSAGDVKEVT"
     gene            6073..6255
                     /locus_tag="J8S10_002709"
     CDS             6073..6255
                     /locus_tag="J8S10_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HAZ9631268.1"
                     /translation="MINLFLLVTASTLFFTGISLIISYLIYKKAENHTSKAIGLAVSS
                     FLTLLTLFVTLSFSFV"
     gene            6358..6642
                     /locus_tag="J8S10_002710"
     CDS             6358..6642
                     /locus_tag="J8S10_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631269.1"
                     /translation="MLTATLQQPTHVAIAESYTINAGIVKQLIKDREFKKFNSRQAYN
                     RQLKKAILKHKDSFIGNLESVDVKTVSTAFSVVEVTIDGRLISLFAFGIN"
     gene            6658..6894
                     /locus_tag="J8S10_002711"
     CDS             6658..6894
                     /locus_tag="J8S10_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631270.1"
                     /translation="MEGKTFAEIWTEFIEVPTRIDPITSEKVLDADFYNLKAGTSLEC
                     VWMYLEEHFKGVTLGHVLYHNGAEWDAIGNIHFS"
     gene            6916..7170
                     /locus_tag="J8S10_002712"
     CDS             6916..7170
                     /locus_tag="J8S10_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631271.1"
                     /translation="MNYTDEEQIALEYVFTNEEGEEIEKVLIISSKDLEKALAYEPYE
                     STVTVIEFLDTYTSNDTWEIMNICNANNIQFAEKTNKSFY"
BASE COUNT         2492 a         1188 c         1107 g         2396 t
ORIGIN      
        1 acttttgttt cgtgttaagt ttctttacat tcctacgcac cttgcgtgta aaatttcttt
       61 attcctccca cgctccatgt tattttatat ttcctttttc atgttatttt tatccagaaa
      121 ccgaacaagt ttttacctat tcccaaaatt aatttattcg ttattttttc attgattaag
      181 aataattatt tgatgcttaa attagctaaa aaaacgattt tttactgata taatcatgat
      241 attaaagctg aattaggcgg aaagataaaa tgttcgcaaa atcaaagtat caattatctt
      301 gtttttttat aaatttgtaa gtaaaaatct aaaaagtttt cttttaattg gtatatgtat
      361 taaaatcaca ttcaatcact cataaaagta tgcgctttca ttttttttgg atgagattaa
      421 tatcaataaa taacgatgta aaaaccatta attatgctct tttataagga tattaattaa
      481 tctaatttga aaaaataatt caaaatttaa atgttttaat attacaaata aaatcatgtt
      541 atcgtaaaat ggtataaaaa agctaaatat tctatttttg ttattttatt agcagggaaa
      601 tttaaatagt ttacaagaat ccgtagaaat atattggttt tgccttcaga ttaatactgg
      661 atcatattaa tctgaatata atatatgaac taataaatag cttaacctcg ctattttgtt
      721 ttttctgatc actatctata cagcattagt aaatagaatt ttaaaaataa aaaaattaag
      781 acaaaaaaag tatcaacata aacatataca tatacacgtt tatgttgata cacttaattt
      841 gtcctttaaa aagcacttat tttaatatta tgttatttta taatcttatt acaagctgat
      901 tgttagacgt tgtcctttca ttacatttat taacggttat tttatcgttt aatttattaa
      961 ttatttttga tctaaaactt agcttaacaa ataaataatt aaccaaccgc cagataaaaa
     1021 tgcgatcatt gctaatacat aagcaaagat aaaaatatgt tcgatcagct taaaccctga
     1081 tgcgattaag cagaccaagt aaaatagaaa ttctcttaca gataatggta attttctaac
     1141 tagcatactc ataattaaca ccccaaagta atattgtatt ttgaacattt tacatccaat
     1201 acagcatcaa tcaaccattg ccaatcaaaa atacaaggct tcattgaagt atgtttttca
     1261 gatgaaaaga tataatataa tttcttcgga ataatatttt cagttgttgg gatcaagcta
     1321 aatttaatac catctaactc atagctacca gctttctctc cattaaaaat ttccttagca
     1381 ctttcttcta aagaatcaaa atatttttcg acagcaacct ttgaagcttt tactattgaa
     1441 gcatttccct tttcgataaa atctgctttt gttttaccga caataagtaa ttcttgatca
     1501 gtaaaatctt ctaaaataat agtagtgtaa ttcttatttc ttctcaatcg catcaggatc
     1561 actccttaat ataatttatg cttttataat atcataataa gataaatttg caagtgttta
     1621 tttacacctt tttatttaca ctttattgta attgattata cttttttgat tgcatttttt
     1681 tcttataaac agttgcaact attagtaaat aggtgtaaac tattttcgta ccgaaatacc
     1741 ataaacacaa acagaaagag gtcataccat gaaagaacca ttattgtttt ccgttgactt
     1801 agggaataaa tcagtaaaag aaatgagtac acacgtttct ccactctcgc ttccctctcg
     1861 tattttgaac aaaaatatca ttaattcagg acgtttttct aatataggtt cctcattaaa
     1921 acgatcacta aacgtttctg aatatagcct agtaaacact actgaaagct attattttgg
     1981 gaaggatata cacgagctag gaaaagatga ctacgtgata gaatcactag gttttgggat
     2041 cagcagatac aagcaggaaa cctaccaaga tatcctatct ttctctttag ctaacctagc
     2101 acgtttagaa gatcaatctg atgacgtttt aaccgttaat ctagttttag gtctgccttc
     2161 atccgactat accgaaacaa tcgtcaaata cgtgatgcaa caagccacac gacaacattc
     2221 agttgaagtt gacggtaaag cttataatat aaacgtagat accgtttggg tactgccaca
     2281 gccgattgga acactatata acctcctcct tgctgatgat ggtagtgtac aagatgaatc
     2341 attgatcagt cagaagatcg gttttgttga tattggtggt ggcacgaaac tttttgatgt
     2401 tgtccaaaat tttgaaattg acgaaaacaa ccgtgaacaa aaggataccg gtatttttac
     2461 tttatataat cgtatcgtaa atatgcttga ccttccgatc agtcctaatg ctttccaact
     2521 tgaaaagatt atccgagaag gcaaagaaaa aggcgtatat ctatttaaac caagcggaaa
     2581 tgaaagtttt gatatttcag aagtagttga aagagaaata aaaacataca ccaatatggt
     2641 tgttgcagaa gttttagcta cattcaaaaa cttcacaacc ttagataaag ttgtctttac
     2701 tggtggtggg gcttctatta tcgacaaaca acttgtaaaa gataaaattc cgcatacctt
     2761 gtttgttgaa gacagtgaat tttctaatgt aaaaggcttt tacaagtttg gtttaactca
     2821 ataaaacagc gaaggagatc aacatgaata agggaaaatc agagcgttat gtagttataa
     2881 tcaatagaga aaaggttagc gagttacctt tagcagagtt tcttgaatct gaatatgaaa
     2941 cactaggcgt taaatactct cagacgatca aaaaagcttt gaatctatat cggcgtgtaa
     3001 agaacaatga agttacaatt attgaagcag gcaacgatag aaacgatagc aaagtagctg
     3061 aagtaaagaa taaaccaact gatcataacc ctattcaaca agcgcatcct tcaacggtta
     3121 catccgatca ttcagcaaag aaagaaaagc caatgctaaa agggttcaat gcaccaagta
     3181 acaaagactt actttaaaaa taaaaaggcg aggttacaat acctagcctt tttattatgt
     3241 acaaatacaa acataaacat atacgtatac atgtatataa acatgtatac gtatatatcc
     3301 ataaacacgt atacgaaatt tagttaagct atacctaacc gcttattcca ataaaaaaag
     3361 tgatcagctt taaactgatc actcaccaaa aacttcatca tacaagttat ctatcatttc
     3421 accaagtaaa gctgaatctg atcgaattcc taacttttcg ctgattttag atagtttctt
     3481 tctttgtgat ggttgaagcg tgaattgata atttttcttc ttttcagaac tatcactttt
     3541 tagtttagct accaaagaac ttgttgtttc tttaggtgtt tgtttaggtt cttcaactgc
     3601 ttcaaccact tcaggaactt cttctacttc agcttcagcg aattttttaa atctattttc
     3661 tttcacttca atcactcctt attcttgtgc cgtatcaatt attttgttgt atagcgtaaa
     3721 cgtgctttca aagaaatcct tattcttacg atagatattc ttatccttag cgaactcagc
     3781 aatattctta ccttctaagc tagttgcatt aagcaattcc ttctcttgta catatccaag
     3841 ataattagat aacgttggta ccaattctag gaactcacga cttgaattag tattatgttt
     3901 gatcctgcta ccgatcgtag cgtatttagt ttccatcagt gtttcaccag tcttaatatc
     3961 aatcaactgt tttgctagtg catcaatatc tttaccaagc ttaagcaaag cttcaaaacc
     4021 atctttagat ggatcagaaa tgcctacgac aagatcagat acagcccaag cattttgagc
     4081 tagtagacct gcatcattat gagtatcaat cagaattaga tcatacttct ctttaagctg
     4141 ttcatagtta acaacgatcc atctaaacag tagggttctg ttgttaggca tatcacgcat
     4201 ttgcatctca acttgtttta aatcttcacc tgctactaaa atatccatgt tctcatttat
     4261 agctaaaggt tcagctgatc catgaagata taaatgattg attgtattct ctcttttcgc
     4321 tttactgaaa gcatcaggaa atcgttttga taggttttgc gacttatctt catcaatata
     4381 cagcaccttc atacctaaat tttcgacagc atatccacct agattgtaga ttgttgttgt
     4441 tttacctgtt ccaccttttt caatgtttcc agtaatgatt gacaacttct tttccatgat
     4501 taaacctccc ttattaatct tttgtaactc cattatacac tataaacacg tttatgtata
     4561 tatttatata cataaacgtg tttatattta tatttgcttt tatattctac aacataaaca
     4621 tatatatgta tatgtttatg tttatgtata tattcaaata tataactatt gcatttgtca
     4681 tacaatcgta gtacaatgta attgaaaagg agttgataaa ctatgccagt aataagtatt
     4741 cgtgtatcta aagaagaaaa agattttctt gaaaaagttg ctgaattcaa cggagataac
     4801 atttctgaat ttatgcgtag taattccctg caaacagcag aaacgttagt agactttgcc
     4861 acctacaagc aactaatgaa agagcatgag gaaaacgatc aaagtatttc ccacgaagat
     4921 atgctaaaag agttaggctt ataagatgac ttaccaagta agatatgaac gtgaagctca
     4981 aaaagcgcta aaaaaaatgg ataagtttca ggcaaaggtt atcctaaact ggatcgagaa
     5041 aaatcttgta ggcactgatg atccaagaaa gcatggtaaa ggtctaacag ctaataaatc
     5101 aggctactgg cgatataggg taggtgcata ccgtataata gctgatatta gcgagcatga
     5161 agtgacaatt cttatattgt ctattggtca cagaagtgaa gtttataagt aacagacaag
     5221 ctgataaggc ttgtctgttt ttttgttaac ccaacaaaat cactgtttac gatcccactt
     5281 tacctaaaaa agaacaatat cctcttgata ttatacacac cagtgtgtat aatataagtg
     5341 taaacaagct aattaacttt caaaaggagc gattttttat gggatggtat ggtgattatt
     5401 catcagcaaa tgaagtgatc gaagaaaaga aagggtacgc caaaaatggt ttggaaatcg
     5461 taggtaccaa agtaacgaag acctatggaa ttatcctttt caaagatgca gaaggaacct
     5521 acgatattga cagcttcatc tttcgagatg aaatgtacaa accaatctac ttcttaaatg
     5581 acagtcctgc ttactttaag aaaattccga aaaaatggtt gaaattcttt gtcggtgatc
     5641 aagaaaaaat ggttaagcta caactagata gaattaaaga agaaagcaat aaaccaaaac
     5701 ttgatgactt attagttgca ggtaaaactt actcaatctg ggatggatcg tatgtcgctg
     5761 tctatcagta taaactcaaa cgtagcttta tttttcgact acaagatgga tcactcactc
     5821 ggttcactcg actatcagca ggagatgtta aggaagtaac ctaaaactta aatacataaa
     5881 cataaacgtg tatacgttta tgtttatgta tatgtatatg aatataaacg tattaggtac
     5941 gaacactttt aaattctttt ctgggctttg tttttagggt agggctaaaa aaaacatcac
     6001 catctgatcc aaaacagctc agaaacgcat ttaaacgtat ctgataccaa tattacagaa
     6061 ggagtgtatc gtatgattaa cctatttctt ttagtgacag ctagtacatt attctttact
     6121 ggaatatcac tgataatttc ctatttgatc tataagaaag ccgaaaatca cacaagcaaa
     6181 gcaatcggac tagccgtttc atccttttta actttgctga ctttatttgt tactttatcg
     6241 ttttcttttg tttagaacag ctgatccatt agcacctttt tctctttaca ttatacacac
     6301 tgttgtgtat aatgtatttg taaacaagct aattaacttt taggaaggag tgacaagatg
     6361 ctaacagcta ctttacagca acctactcac gttgctattg cagaaagtta tacaattaat
     6421 gcagggatcg ttaaacagct gatcaaggat cgagaattca aaaagtttaa cagtcggcaa
     6481 gcgtataaca gacagctaaa gaaagctatt ctaaagcaca aagattcctt catcgggaac
     6541 ttggaaagtg tagatgttaa aactgtttca acggcatttt cagttgttga agtgactatt
     6601 gacggtcgct tgatttctct atttgctttt ggaattaatt gatagggagt gtgaactttg
     6661 gaaggtaaga cttttgcaga aatttggact gaatttattg aggtaccaac tcgcattgat
     6721 ccgataactt ctgaaaaggt attggatgca gacttctaca atctcaaagc aggtactagc
     6781 cttgaatgcg tttggatgta tttagaagag catttcaaag gcgtaacgct cggtcacgtc
     6841 ttataccaca atggtgccga gtgggatgca attggaaata tccatttttc ttaatataag
     6901 aaaggagaac acaatatgaa ttataccgat gaagaacaaa tcgctttgga atacgttttc
     6961 acaaatgaag aaggggagga aattgaaaaa gtcttgatca tttcatcaaa agacttggag
     7021 aaggctttgg cttatgaacc atacgaatca accgtaactg tcattgaatt cttagatacc
     7081 tatacttcta atgatacttg ggaaattatg aatatttgca acgctaataa cattcaattt
     7141 gctgaaaaaa ccaataaatc attttattag ttttgcaata aaa
//
LOCUS       DADQDV010000105         7140 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.108, whole genome shotgun sequence.
ACCESSION   DADQDV010000105 DADQDV010000000
VERSION     DADQDV010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7140)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7140)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7140
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.108"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..614
                     /locus_tag="J8S10_002713"
     CDS             <1..614
                     /locus_tag="J8S10_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HAZ9631272.1"
                     /translation="VFAPLEGEDLASFLVGAAIMMIGMTLFLFGADYSMMEVGDLVGK
                     YMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQQVYDISDGEIGRVLLIGIVSVGTG
                     VFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFTSSEFMPIAFDSGGVTTGPVTVPFI
                     LALAGGMTSMIKQKKNENDSFGMVGIASLGPILAVMILGVIFQ"
     gene            611..1384
                     /locus_tag="J8S10_002714"
     CDS             611..1384
                     /locus_tag="J8S10_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HAZ9631273.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            1381..1779
                     /locus_tag="J8S10_002715"
     CDS             1381..1779
                     /locus_tag="J8S10_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HAZ9631274.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            1964..2635
                     /locus_tag="J8S10_002716"
     CDS             1964..2635
                     /locus_tag="J8S10_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631275.1"
                     /translation="MNFLVVLKDTLIERFTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            2694..3134
                     /locus_tag="J8S10_002717"
     CDS             2694..3134
                     /locus_tag="J8S10_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631276.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            3146..3814
                     /locus_tag="J8S10_002718"
     CDS             3146..3814
                     /locus_tag="J8S10_002718"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HAZ9631277.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            3878..4501
                     /locus_tag="J8S10_002719"
     CDS             3878..4501
                     /locus_tag="J8S10_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HAZ9631278.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            4557..4943
                     /locus_tag="J8S10_002720"
     CDS             4557..4943
                     /locus_tag="J8S10_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HAZ9631279.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            5156..6547
                     /locus_tag="J8S10_002721"
     CDS             5156..6547
                     /locus_tag="J8S10_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HAZ9631280.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
BASE COUNT         2277 a         1160 c         1572 g         2131 t
ORIGIN      
        1 ttgtttttgc accgttagaa ggagaagacc tcgcttcatt tctggttggt gcggcaatca
       61 tgatgatcgg aatgacgctc tttttgtttg gagcagatta ttctatgatg gaagtcggag
      121 atctagtagg gaaatatatg atcaaaaaga aaagtttgac cgttttggtc agtttgggat
      181 ttgctatcgg gatcgtgatc acgattgctg aaccttccgt gcaagttttg ggacaacaag
      241 tatatgatat atctgacgga gagattggca gagtgttgct gattgggatc gtcagcgtcg
      301 gcactggagt atttctagcc tttgcgctgc ttcgggtcgt attcaagcta tcctattatc
      361 aattgatggc tataggctac ataggcgttt tgatcgcctc atttttcacc agttccgaat
      421 ttatgccgat tgcttttgat tcggggggag tgactactgg tccagtaact gttccattta
      481 tcttggccct tgccggaggg atgactagta tgatcaaaca aaagaaaaat gaaaatgaca
      541 gttttggaat ggtcggtatt gcttcgttag ggccgattct tgccgtgatg attttggggg
      601 tgatcttcca atgagtttct ggcagcaagt gatagatgga atcgaaatcg ttaccatgga
      661 agtcattttg gcagtggcac ctatcgtaat cctatttgtt ttaatgaata tcattagttt
      721 tcgtatgcgc aaaaagcgtt tctttgacat tatgaaaggt ttcttgataa cgactattgg
      781 gttgatcctt ttcctgcacg gagtcaatat ggcttatgta ccggtaggac agcatttagg
      841 cagtgctatt gcgggattgc cttacaatta tatactggtt ccccttggct ttttaatggg
      901 gttcttagta gggtttgctg agccggcgat tcatgtaatg atcaaacagg ttgaagaatt
      961 gagcgagggg agaatccgat cgaaaatcat gctgatggta atttcaattg ggatcggcgc
     1021 agcagtagga ttgtctatgt ggcgtttgct cgtcggattc tctctttatt atttcttgat
     1081 cccaggatac gggctagcat ttattttagg acgaaaagtg gacaagatct ttttagcaat
     1141 ggcttttgat aacggtggag tagcaacggg cccgatgtgt tcgacattta ttttatcaat
     1201 gagcgtggca atcgctgcac aaattgaagg aagagatccg atcattgacg ggtttggtgt
     1261 ggttgcaatg attgcattga caccaatatt atccacttta gtactaggat atatttataa
     1321 acgaaaagat gaaaaagaca gaatcgaaaa agaaagattg caaaaattgg gggaaagcaa
     1381 atgaaagatc ttgtagcatt gaatcttcac atgattgtga cgatcgttga cggaggaatg
     1441 ggcgaagatg ttatcgactt ttcaaaagaa gcaggtgcag caggcggaac gatcttacat
     1501 ggaagaggtt ctggtgtaca tgattcaggg aaatttttag gtttggacat ttcgccagaa
     1561 aaagatattg tgttgacatt agtacccgat agtttgacga ataaagtaat ggatgcgatt
     1621 ggtcaaggca tcaacatcga tattccaggt aatggtattt gttttagtat tgatgtagac
     1681 aaagtcattg gtatcactaa gattcatcaa tatcgagaaa ttatcggaat gcaagaactt
     1741 ttagatgaaa ataacgatag agaaaagtct gaatcataga caagcgtttg aagaggaaat
     1801 aaacacaaac aagaaggcgg atgagcgtta tttccgcttt tttgtttgta tttttctcgt
     1861 gaatacttat gaaatagtaa atttttatga aattctactc taagcatcag actttctttt
     1921 caaaatatgc tattttaaaa atgatgaaaa aagggggaga aaaatgaatt ttttagttgt
     1981 tttaaaagat actctgattg agcgatttac atttctatat gttcaattgc aggaaaataa
     2041 aacattgctg catttttcac cagagttcca tctagagggg ctaacattag gagaaatcta
     2101 tcaagcagaa gggctgtcgg ctgttttgca cttttttaag gtagaattgg aattaccagt
     2161 aaaagattat atcgagcttt ctcttgaatc ttgggatcga gcagtggttg aactgtttcc
     2221 agaaggttta atgatcgata caaacgatgg gaagatccat ctgactgcag cagaactgca
     2281 aaaacaaatg cgttatcaaa tagatgacga aaattctttt tctattttta gacgtcagca
     2341 aaagattcta aaaagctttt taaaagtgat cagtaaaaaa cggaatctga tcaaaacgac
     2401 acagctgttg aaaaaatatc caggtctgct tcacacgtct attcaatttc ctcaattgat
     2461 tacgatgatc catcgtttta tacgtatgca acagctacca tctaagaagc tgtttcttcc
     2521 attgacggac acatttcgag tagtcaacag agaagataaa aagaaagtga ttgtgattga
     2581 ctttaccaga aatcggaatg tccttcacca agttgcaatg gaaaaggcca attaaggctt
     2641 tttctttttg gatttttttg tcataataaa tattagatga tggaggagat aatatgatgc
     2701 aaacatggtt agaaaggcta atacgatttc agcagaacta tcacaaactt atgcagggaa
     2761 gatatgcgaa atttgatcag ttgaatcgcg gtctattgat cgctgcgctt gtctttagtt
     2821 tgctaagtcg ttggttgccc tatagaatcg gacaattgtt gttcatcgtc tttttcggat
     2881 ggatgatatt tcgtttccta tcaaaaaaaa tctaccccag actaaatgag aatcaacgtt
     2941 atttgaaata tcttgataga gtcaaagaaa aatatcatca gataaaaaac aaaaagcaag
     3001 tcaaaatgga tcgaaaaagt tatacttttt ttgagtgccc gaattgtcat caaaagcagc
     3061 gtgcacctaa aggaaaagga cgaatacgtg tgacatgcaa aacatgtggt ataaaattcg
     3121 aaacgaatgt ttaagggaga aaagaatgaa attagtatta ttacgtcatg gcgaaagcga
     3181 agcaaatttt gaaaattact ggacaggatg gctagatgtc gccttaacag aaaaaggaaa
     3241 agaacaagca gcagttgccg gtcaaaaaat gcttgaagcc ggacttcaat tcgatgccgt
     3301 ttatacctct gttttgaaac gtgcgattct taccggacaa gtcgcactag aagaaatggg
     3361 tcagttatgg cttcctataa taaaaacatg gcgtctaaat gaacggcatt atggggatct
     3421 tgtgggtaaa aacaaagata agatgaaaga aatatacgga aaagatcaag taaaaacatg
     3481 gcgcagagga tatacggaag ttccgccgtt aaccgcagaa aatagatttg accgcagata
     3541 tgatcacttg gatccgcatt tgatcccata cggagaaagt ctggaaatga cagtgaatcg
     3601 gatcattccc ttatggcaag atcatctagc accaaaacta aaagatcggc aagatttact
     3661 agttgtgggt catggtaata gcatccgagc actgacaaaa tatttagaag atgttcctga
     3721 agatcaaatg gatacgatcg atatcccaaa tgcacaacca atccagtata cattagcaga
     3781 tgatttgaca attctggaca aaaaaatact ttaaagaaca cctttatcta aaagtgagag
     3841 atagaaaaaa gaagcaaagg aatggaacaa aaggaacatg aaaaattata tatgggactt
     3901 tgatggtaca ttgtttgata cgtatcccgc aatggtagat ggtgcatggc aagcactaaa
     3961 agattttggt atcagtatgg acaaaaaaga aatctacttc aaaatgaaaa agtattctac
     4021 tagttatttg atcaatgaat caaacttgaa tgccagagag tttaatgaat tatttcaccg
     4081 atatgaaaaa gaaagtacgg aagtttcccg tccatttcca gaaacgaaac aagtactgga
     4141 aatgctaaaa gacaacggcg gtcgtcattt catcctgacc caccgtttga cagaatcaac
     4201 atggggcctg ttaaaagaac atcgattggc acatctgatt gaggaagtag tagggatcga
     4261 tcaggacttt cctcgtaaac ctgatccagc atctttaaat tatttgatcg atacttttca
     4321 tttagaaaga acagacacga tgatgatcgg cgatcgtcgt ttagatatcg aagcagggaa
     4381 aaatgcagga gtcgctactt gtctttacga catcgatcat tttctgggtg agatcccggc
     4441 agattatgtg gtaggaaatc tgaatgaaat ccttaccttg cagagcatca ttaaaaagta
     4501 gtatcccctt tcaaaggaga tatgttataa ttttcataaa ggagtgataa aattatatgg
     4561 aaatcagaag acaaaaagaa gttgtagaag catttcatta tgatatgaga ttgccgaacc
     4621 aagaagtaga aacagatttg aaagtaggct tctcgccttt aaaagaaacg atcgaaaact
     4681 atccgaaaga acatagcatc gtaggagcac gcttagagtt ccgtttagtg tttgatacat
     4741 atgttttatc tggaagtgtg agtcagatca atcatatcct caatcggaaa attgaaggtc
     4801 aaaatgatgt cacacaagaa gaagtggacg agctagtagc accgttattc gatatcgtac
     4861 gccgaatgtc ttatgaggtg acagagatcg ccttagatca gcctggggta aaattgaatt
     4921 ttcaatcaga aaaacaagaa tagacagtaa aaacatacct gcgatagatt aaagctatca
     4981 caggtatgtt tttttattac taattgtaag caaaaagaat gtcatttcga taaaaatcgt
     5041 ctaaaatata aaagtcactg aaaaaaattt tttcaggagg atggttgaag aatcattctc
     5101 gggaaccttt acttccttcg atggacttgt cattaataat atgaggagga gaaaaatgac
     5161 aacactcatc acagttttag tggttctagt ttttgcggca ttattatatg tgttctatcg
     5221 tatgcaaaag cgccatacaa aattttcaac acgcgtcttt acagcattag gagttggtat
     5281 cgtctttggc ggtctgcttc aattgatctt tggtgtagac gacaaagtcg ttactcaatc
     5341 aatggaatgg atcgggattg taggtcaagg atatgtatca ttcttgcaaa tgctagttat
     5401 gcctttagtg tttatttcga tcattggtgc attcacaaaa atgaaagttt ctgaaaagct
     5461 agggaaaatt agtgcgactg tattgacttc tttacttgga acaacagcta ttgcagcatt
     5521 gatcggaatt ggttcaacaa tgctgttcgg actccaagga gctaaattca cacaaggagc
     5581 tgcagaaaca gcacgaatct ctgaactggc aacacgtcag gaaacagttg aaaacttatc
     5641 gattccacag cagattttat cctttatccc taaaaacgtt tttgctgatt tagcaggtag
     5701 tcgtgcaaca agtacgattg gagtcgttat tttcgcggca tttgtcggaa tcgcttatct
     5761 aggcgtgaaa agaaaagcgc caaaagaagc agcattcttt tcagatttag tcgacagtct
     5821 gtataaaatc attatgcgga tcgtgacgct tgttttgcgt ttgacacctt atggagtatt
     5881 tgctttgatg acaaacgttt tggcaacaag tgattttgca gctatcgtca atttaggtaa
     5941 atttgtcgtt gcttcttacg tagcattgct tgctgttttg attgtccact cactgatttt
     6001 gattggtgca aaagtcaatc caatcaacta tttcaaaaaa gcctttccgg tattgagctt
     6061 tgcgtttact tcacgttcaa gtgctggagc tttgccattg aatatcgaga ctcagacaaa
     6121 agctttagga gtagatgatg caacagctaa tttctcagca agttttggtt tgtctattgg
     6181 acaaaacggc tgtgctggcg tttatccagc tatgttggca acgatcgtcg caccagcagc
     6241 tggagtgaat gtctttagtt tggaatttat tttgatgctt gtggcaattg taacaatcag
     6301 ttcttttggt gtagctggag tcggtggggg cgcaacattt gcttcactga tcgttttagg
     6361 ggcaatgaac ttgccagtag caatcgttgg gttagttatc tctgttgaac cattaatcga
     6421 tatggcacgt acagcagtaa acgtcagcgg tagcatggta gctggtatcg tgacaagtgc
     6481 acgcatcaaa gatttagatc gcgatgtcat caatgatgat tctaaagtga tcgatgtgaa
     6541 tgcatagtca aaaagaggtt gtgatagaag tggtcagctt taagaaataa gaagaagttt
     6601 cctaaaaata gtttctcaaa tttttgtgaa atttcggctt atttccgaga agctacttct
     6661 gaaacaccgt gaataagagg ttgtgaaaaa gctgccctgc atcaagtaat aagaacagcc
     6721 aaacaaaaat agttcctcat attttacgtt tggttgagct tattaccgca gatgcaagct
     6781 tttgaacacc gtttaagaaa gaggtcgtga gcctgccgtt tcactctgag tcacaaagag
     6841 caatttcaaa aaatagcttc tcatgtttgt tgaatattgt gtcttgtgac cgaggagttg
     6901 tcaggagaac accgtttacc agaggttgtg acttgttttt agtcacgacc tcttttttta
     6961 tttattccat ataaatacac attatttatt ccgaaaagtg aaagcgcaaa taacaaaaac
     7021 aaccaactta tttattatta aagaaaagcg tatttaagta ggacgattct gttgagagct
     7081 ttcgtagatt ttcccatttt cctatggtaa actgacaaag ttgagaatgt tagaacagat
//
LOCUS       DADQDV010000106         6963 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.109, whole genome shotgun sequence.
ACCESSION   DADQDV010000106 DADQDV010000000
VERSION     DADQDV010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6963)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6963)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6963
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.109"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            275..871
                     /locus_tag="J8S10_002722"
     CDS             275..871
                     /locus_tag="J8S10_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAZ9631281.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAEEKEYMNDADRFRVFG"
     gene            complement(929..1411)
                     /locus_tag="J8S10_002723"
     CDS             complement(929..1411)
                     /locus_tag="J8S10_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631282.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(1517..1714)
                     /locus_tag="J8S10_002724"
     CDS             complement(1517..1714)
                     /locus_tag="J8S10_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631283.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            2009..2767
                     /locus_tag="J8S10_002725"
     CDS             2009..2767
                     /locus_tag="J8S10_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HAZ9631284.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            2827..3255
                     /locus_tag="J8S10_002726"
     CDS             2827..3255
                     /locus_tag="J8S10_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631285.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            3301..3373
                     /locus_tag="J8S10_002727"
     tRNA            3301..3373
                     /locus_tag="J8S10_002727"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3334..3336,aa:Gln,seq:ctg)
     gene            complement(3523..3894)
                     /locus_tag="J8S10_002728"
     CDS             complement(3523..3894)
                     /locus_tag="J8S10_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAZ9631286.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            4109..4294
                     /locus_tag="J8S10_002729"
     CDS             4109..4294
                     /locus_tag="J8S10_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631287.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            complement(4377..4565)
                     /locus_tag="J8S10_002730"
     CDS             complement(4377..4565)
                     /locus_tag="J8S10_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631288.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(4589..4852)
                     /locus_tag="J8S10_002731"
     CDS             complement(4589..4852)
                     /locus_tag="J8S10_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631289.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            5010..5267
                     /locus_tag="J8S10_002732"
     CDS             5010..5267
                     /locus_tag="J8S10_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HAZ9631290.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            complement(5338..5529)
                     /locus_tag="J8S10_002733"
     CDS             complement(5338..5529)
                     /locus_tag="J8S10_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631291.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(5670..5990)
                     /locus_tag="J8S10_002734"
     CDS             complement(5670..5990)
                     /locus_tag="J8S10_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631292.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            complement(6013..6447)
                     /locus_tag="J8S10_002735"
     CDS             complement(6013..6447)
                     /locus_tag="J8S10_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAZ9631293.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            6782..>6963
                     /locus_tag="J8S10_002736"
     CDS             6782..>6963
                     /locus_tag="J8S10_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAZ9631294.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNS"
BASE COUNT         2178 a         1359 c         1067 g         2359 t
ORIGIN      
        1 atttttaatg gcaatatcat aaaaaaaaga agatagagat ttaataatta tatatcagct
       61 gtttttttca aataagcaaa aattcctaaa acacaacaat gaaagcgata actaagaaaa
      121 tccttacata acgatttttc ttattaaaat tgttttttga acttcgctta ttttttgtga
      181 gcatatctgt ttacttactt tttgtaaggt gctatacttc atttcgtaat caattaaaaa
      241 aatgcaaaac gcaaatcaaa ggagaaattt tattatgaca acttttactg acactttgaa
      301 aaaccgccgt tcaatctatc atctaggacg taatgtttca ctttctaatg aagaattaac
      361 aactttgatc aaagaagcaa ttaaagaaag cccaactgct ttcaatgctc aatcaacacg
      421 cgcagttatc cttttcggag atgcacatga aaaactttgg gaaatcactg aagaagcact
      481 tcgcccattg actccagcag aagctttccc aaatacacaa aacaaattag ctggtttcaa
      541 aaatggttat ggtacagtat tattcttcaa agatactgac gtggtaaaag gtctacaaga
      601 acaatttgaa ttatatgcag acaacttccc agattggtca gaacaatcaa acggaatcgc
      661 aacagctaat acttgggtag cattagttga taaaggattg ggcgcaaact tgcaacatta
      721 caacccagtt attgacgaag cagttgcaaa agaatggaat atcccttcaa actggaaact
      781 acgttcgcaa ttagtattcg gttcaccaga aacaccggct gaggaaaaag aatacatgaa
      841 cgatgccgat cgcttccgcg tatttggata attttatttg aaataaaaaa cagaggttgt
      901 gacaaacatc ttgtcgcaac ctctgttttt attctggatc aatcataata tcaatctctg
      961 cctcatcgtt taagcgttgg gacaaaaatg gaactaattc ttctaatgat gcagaaaatt
     1021 tcagcatcgg tcctcgccat ccgtttcgga aaaaattcat ttttacgatt ttagaacctt
     1081 ttggctgata taatacaatt ttattgatct cagaaaaagg aacacctttt ttgtcaaagc
     1141 tattcaaaac aagtccttct tctgtgattc ctctactgtc caacaaaaaa ctaataaaaa
     1201 tcattgctga caagatccct tttgccaatt catctgctgt aggatgactg atgagtgtat
     1261 accaaatgac tagtgacact aagaagggta tcaccaagta gacccatcga tttcgcacag
     1321 tccgataaat aatttctttt cgaaccagcc aaagaaataa aaacatcaca acaacgaata
     1381 aaaacaatag aaccgtaaag aatgttacca tgacaactcg cctcgctttt tcttctccag
     1441 aaaataggaa aagaatactg atttaccttc tcaaagaaat tggacttgca gcacgccgca
     1501 cgtccaattg ttttctttat tcaaatgtat catattttgc aacaaccatg cttgcttttt
     1561 catctaataa ttcttggtcc tctgcagcac attgggcaac tttgaccacg gcgcagtttg
     1621 tcatttttga tacaacttca ccaatgaccg tttttgtaaa accaattggt ttgcatgcat
     1681 attgttctcc taaattaatc atttcttccg tcatcaaaat cctcctaaac tgctggaact
     1741 tttctccaca ttaccactgc tatttctttg gagatttaac tcattgattt ttatttacag
     1801 ttaaaaatca accttacagg cattatagcg tactgttttc gttttcacaa ttaaaacagc
     1861 tgttgtattt agaagaattt ttttcaaaaa attaaaacat attccttaaa aactaattat
     1921 ttcctacata ttaaaatata atacttccat ttccaataaa aatacattta taataggaaa
     1981 gataaacagc tgaaaaggga gatttcaaat gaagaaaaaa acgttcaaaa aactattgtt
     2041 tctagggggc acagctgctc ttttattaag cggtacaagt tattacctac atatccattc
     2101 tccagaacat acaatgaaca ctgcacaaaa aagttcaaca caaaaaacga aaaagacaaa
     2161 agagaaagca gaagttttac tagatgttcc attagagagc cagtttgatt ctccttcttt
     2221 agaaaatggc tgtgaagtca cttcgctttc tatgctttta tctttttatg gttatgaaac
     2281 aactaaaaac cagttagctg agcaattgga ttacgtccct gttttcaatg cagatgggac
     2341 tcatggcgat cctaatgaag gatttgttgg tgatatcagt ggcggagact gggctatggt
     2401 cgtctatgtt cccccagttg cctcccttgc tcagcaaatc gtccaaacgg attatcacac
     2461 ttttccaaaa accgatgctc aactcgatga tatcaaaaaa gcactatcta aaggaaatcc
     2521 tgtctggact tctgtgacta tcaattttga agtcccagat gaaactgatt ttatgacttg
     2581 gaccacaaat aatggagaag taagagtcac tcctcttgtt catgcttgtg tagtcactgg
     2641 atatgacaaa gaaaatattt atgtcaacga tccctatggt gtaaaaaatc gagcagtacc
     2701 gatcaacgat ttttcggcga ttttcactgc aatgggtgga cagatgctaa ctttggagaa
     2761 aagctagtaa ttcaaacaaa aatcccttat actcaagata ccaaaccttt gaagggagcg
     2821 tagataatgg aaaaattcac acataaaaaa atggatccaa atgaaattcc gattattttt
     2881 gtccgtgact gcaagggaaa tgttcaaggt aaagtctcta ttaatgagtg gaacgagcgt
     2941 cgcagacctg ctaccctcaa tgaactggaa atcaaattgt atcgtcaatc tcttgtttat
     3001 tacgcagatc aagagtacga gaaagccacc gatttattga aatttctaat tgctcgaaca
     3061 gagtatactc gctttgaata tattgaacgt ttagcaaaca tctatcatat tatgaatgaa
     3121 cctgtcaaag aatatcagtt attggacacc gtcttgtcag tagcagaact gattgccctt
     3181 cctgctggat tagaaaagaa actagtacgc cgccttttac gagtaaagca acaactatcc
     3241 gatcaagaaa aataacttgc gtttttttag gaaagtgcta tgattatttt gttgaataaa
     3301 tgggatgtag ccaaactggt aaggcacttg actctgaatc aagcaattgt aggttcgaac
     3361 cctgccatcc caatttgatg tgcttgctga aaaaatgaac cccctgtaaa agaacaatct
     3421 ttttgcaggg ggattattgt attattttta ctacttgtat ttagtttaca taattaaatt
     3481 atgaataata aaatcgggcg tattcttaat acaaaaactg atttacccaa taattgctaa
     3541 tgctttctcc ggaacttttt ctctaggaac ttcctcatac gtttctatgt gtgctccttt
     3601 attgctaatt ttcaaataat gattttcttt taacacagaa agaccattaa attcaaccgt
     3661 tcgttctttc ccattggcat cagcagcttt ctgcacatac cttgctgtac catattcatt
     3721 tacttcctct ggtttttgtg tctttacata gacctctcct ttttcaacta atggatttag
     3781 ctgatcaagt ataccaggga tttctccata acttccttca gtataatatt tcagtccaaa
     3841 tagcaaaata ccactaatcg ccgccagtcc aatcaaatat ttaatcactt tcatctttct
     3901 acctccttgt tatatattca gtatatgggt cagttaaaga aattccatcc gtcccaagtt
     3961 ggagattttt ctcctacttt agaagcgaga atcgagtgtt tttttagtaa aaatgatcgt
     4021 tatttgatat tattgacgtg tggataaatc agtttttctc gttttgtcca tgtaaaaaat
     4081 catgttgata gcaaaggatg tgttcaaaat gaatcaagaa gaattatttc aaaaagtcaa
     4141 ggaaatgatt aagaacggca atttcgatgg cgcaaaacga tttatcgaag aacataaaga
     4201 acaattagga ccttataaag agaaagccca aaatctttta aaagatgtaa atatcgacag
     4261 tgtcaaaaac aaatttaaaa atctattcaa ataagtaaaa ctttcacttt tgtaaaatca
     4321 aaggaggaca atgctgctgc atcgtcctcc tttggttctt ttctgaatac ttcatactaa
     4381 aataaacgtg tcggatcgta atgataagtc acattgccgt tcagtgaggc ttttcccacc
     4441 acatatttac gattctccaa cttcagccac gcttctcgaa aagccattaa ttcttctctt
     4501 tttacatcaa tcttttcgat ttttccatcg atcaaatctt gaataagttg ttcatatgga
     4561 ttcatttttt tcctccatct gctgtcaatc aataagttgt aaaaataggt tcatatgctt
     4621 ttttggtatc tagatcttct ctgactttga ctgtcgtata aataattttt tctactggga
     4681 tactataata acttccttca ccattattga atcggtgaac gtctttcttt gctaaaatac
     4741 catttatttt attcgtcagt acacgttgtt cgacactgtt acttacaaca tagtaaatca
     4801 cccgaatatt attgatcaaa tgcaaatcga tttctaacac tacatgatcc atgaaaatcc
     4861 cactccttct ttcactttga ttatagcaag tttctcctct aatttcaaaa tcgatacaga
     4921 ttttaccgga taaatccaca aaactgcttg cgccatttcg cacaaagtgt tattttgtat
     4981 catggacttt atttatcgga ggcaatagta tgatcgcgat cggtcaattt gttttttata
     5041 ttcctttttt tattatgata agcattcttt tctattacat aaaatggaca aaaaagaagt
     5101 tttcagtttt actggcctct ttacctgctg tatattttac ttatcaaatt ttttctttta
     5161 ggcattggga aacaacgtct gtattaataa cacacatcat cgaattgacg ctttcagtaa
     5221 tttttcttat tatttggatc tattttttat ataagaatca gaattgaatc cctcgcatgt
     5281 ttaaaaagaa aacgattaaa gatgcagcaa atttctgccg atctttaatc gttttttcta
     5341 ttctgttata ccaaaaaaat gtttgaatcg gtgaaggatc gttccttgtt ttaattctat
     5401 aaattcttgt gcgatcgggt acttttcttc caaattttct ttgttctttt cgatcaggct
     5461 tttcgcttct tcatattttt tatctgcaca tagtgctttt acttcctgta atacttttcc
     5521 tgcttccatt tgcctcaccc tcttgccatt ttattgcttt aagttttatt taagttatac
     5581 gcattattct agtttcatcc caaataacct tttttcattt ttactcctcg aactaatcag
     5641 ttttctaaag gctgattggt tcgtcttttt tatttttcct ccatttcatt ctgctcttct
     5701 gttaatttat ctaatgcttt gattgatgct gcggctcttg cataatcata gctgtataat
     5761 tccataaatt tatcaggcag aacaaaccac gctggatgat aaccgttagc tgtgacaggg
     5821 aatcctttat cttgttggtt atctccatcc catctcagag caacaccttt ttttcctttc
     5881 cactttacta aagcgatcga gtatcccttc tttgtttgtg tgccgtcttc aataattgct
     5941 aaaatttcta ttttttcttt tggcgcacgg acttcttgag gacgaaccat tttctattcc
     6001 tcccttatct cattacttca cgaccaacac actgcaaggg gcatgtgata cgacataaga
     6061 agcggtcgat ccaactaatg cttgttgtat agcacctttt cctgtcgctc ccataacgat
     6121 caaatcaata ttttcttgtc cagggatgac attggcaatc aaatttcttg gatctccagt
     6181 ttcaactatt gcgtggatct cagcaatgcc gtactctttg gcatcattga tttttttcag
     6241 catggctact tctgttcttt gtttttcatc tgcatagatt tttgaaaagg cataggcact
     6301 atgggtcagc tcaactttgt tgatgattga cacgataaat aagtgggctt cattgtcctt
     6361 tgctaagtca agggcttcag cgaacgcttt gatcgattgt cttgatccgt caactgctac
     6421 catgatgttc tggtatcttt tactcattgg aaccgcctcc tttttctttt attgtaacat
     6481 ctcaagcaaa aatacaaaaa atatacgcaa tatgtaaata aaatgatgaa caaaagcaat
     6541 ttctttcaag ttatttatac atttcttttc tcatcagaac acctgttcta atcccattat
     6601 ttctgcatta tgtgaaattc ctcatcattt ttcacatcga gcgaacatca ttctgttaca
     6661 aaaaacgtgg atttgtcata aattgtcatg cttcttttac ctatgaaata ttttcacgtg
     6721 ttaaagtatt cctcgttgaa cacaacaaat aaaacttttt aacgaataaa ggagattttt
     6781 catgacatca cttaaaactt tactttttgg aacaactttg gctgccggcg ctgcattctt
     6841 catgggaacg actgctcatg cggacgaagc ttataccgtt caatcaggtg atactctatc
     6901 aacgatttct caaaaatacg ttggtgataa ctccttgatc aatgccattg cagaatcaaa
     6961 ttc
//
LOCUS       DADQDV010000107         6902 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.110, whole genome shotgun sequence.
ACCESSION   DADQDV010000107 DADQDV010000000
VERSION     DADQDV010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6902)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6902)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6902
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.110"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..444
                     /locus_tag="J8S10_002737"
     CDS             <1..444
                     /locus_tag="J8S10_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HAZ9631295.1"
                     /translation="KEKQMEEQDFKRFLAMIDECHNAINPDFIETVNYVTNFQREMRK
                     VEAMTVLATQSPQEMVPENMSSDNFSKLKKVFEFSSTKIFMRMDESILRHIEGLVGKS
                     MTNSELESIPQQNQGDAVINFGSKETIRVHFSPNKRQLKLFDGGK"
     gene            444..1643
                     /locus_tag="J8S10_002738"
     CDS             444..1643
                     /locus_tag="J8S10_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HAZ9631296.1"
                     /translation="MENQNESLIKQYVKRRAKRRLFLWVFGTSAGLITILITVFVTLF
                     LILAAGSIDNSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYKLL
                     PSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKFPN
                     SKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSAYYKNCMSII
                     NTNKLMEYDEFAIKHWREGGGTGGTITGSWGNPFPGSSLDKNSFSGGQLFGKNPGGEF
                     RPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVYQE
                     FANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFIDDGTWIDPLP
                     FLNSSKK"
     gene            1659..2303
                     /locus_tag="J8S10_002739"
     CDS             1659..2303
                     /locus_tag="J8S10_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631297.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQETNTYKIEEVAK
                     NASDKLKKNSSEAQAKIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPADDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVTDFSYFTR"
     gene            2314..3120
                     /locus_tag="J8S10_002740"
     CDS             2314..3120
                     /locus_tag="J8S10_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631298.1"
                     /translation="MSKKKGARQRFKKRKSYLRWLGIFMILGFLILASPIYTHKKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIKAKVIKVSDDYFVVKLAHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIYYVH
                     EDKVKDQVKDEDYEQHAINYKVKGYKKEQKAAQKQMESFQATIDLNEELVKKLKDQLP
                     YQVADDQENTENKINSYQQEIETSKTQMKDQEEIIQKLQEKIDRMTKEKI"
     gene            3142..3372
                     /locus_tag="J8S10_002741"
     CDS             3142..3372
                     /locus_tag="J8S10_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631299.1"
                     /translation="MKRTNLADKDTFAEQKVLIKAYLKVVKAKEICREVNLSNTTISE
                     LKNGRKNLDTLKFRSFEALYVAAKKYFTADNK"
     gene            3886..4194
                     /locus_tag="J8S10_002742"
     CDS             3886..4194
                     /locus_tag="J8S10_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631300.1"
                     /translation="MEVRIRNVDEKIVREIDRRCDELSNRTGNKWSRNDYLKLLVEND
                     FDRPLMEYKQDKFDQLLNQLIDKFSFVQSHNTKVLEEYICQNNQIIELLIEQSRGGEV
                     "
     gene            4196..4618
                     /locus_tag="J8S10_002743"
     CDS             4196..4618
                     /locus_tag="J8S10_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631301.1"
                     /translation="MAKVIDKHIYFYETHIDVLDEIIATHAEVKNYSEAVRFLCMNYD
                     SEVEKKVNSNQAKLNAMGKEISILTEMVSEFADLHLKDTGILIGTNSTVYQEAKERVE
                     GKIKANQTKKYSPKIKKTISESVTTKSEVFDPTRFLKR"
     gene            4638..6227
                     /locus_tag="J8S10_002744"
     CDS             4638..6227
                     /locus_tag="J8S10_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631302.1"
                     /translation="MSKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEKERRTPEE
                     EQELRLIKNALEDFYIPEGETFSESKTGKEFSETSNEAQSLMKHGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKVLTHSEQKEYQRLNQAIKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQTFQRGQQKGSIIYQDVVSHDHSYLEKIGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKKNTRKPYTEIENGVSYIVPKG
                     KRRQATLDEMKTNYVHELERFSYEKNRMGMEKRNLLTRKSDLRNTLTKVVKEPVRYDR
                     HAMSLLTEVYKNLPKKRSEWHYGDENRTKLSPYTREKLDELTQYVLTKEPGYQEYIQI
                     SKALKEEAKSLYGESKRESKDAEKNALFDLKKRTGNAILTELKKQDSQIKPLIERMDQ
                     MQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEEK
                     YHASKAYEEQQRRIQMEQERQ"
     gene            6239..6574
                     /locus_tag="J8S10_002745"
     CDS             6239..6574
                     /locus_tag="J8S10_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631303.1"
                     /translation="MKQYLDQWKVIEGSLREERIEQLPDCLEKEHLFQIREMLINEQF
                     DPNQFLVVEYPATGVYCCNHVKGEKYFIIQEYEGKLAPYYTTWEMNEEGINNFPCKSI
                     EESISLTEC"
     gene            6715..>6902
                     /locus_tag="J8S10_002746"
     CDS             6715..>6902
                     /locus_tag="J8S10_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631304.1"
                     /translation="MAYSTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQSGDI
                     LTLNLTTKTFVDAAEDYP"
BASE COUNT         2648 a         1036 c         1419 g         1799 t
ORIGIN      
        1 aaagaaaaac aaatggaaga acaagacttc aaacgcttct tggcgatgat tgatgagtgc
       61 cataatgcga ttaatccaga ttttattgaa acggtaaatt atgtcacaaa ctttcaacga
      121 gaaatgcgta aagtagaagc aatgactgtt ttagctacac aatccccaca agaaatggtg
      181 ccagaaaata tgtcttctga taacttctcg aaactgaaga aagtctttga attttcttct
      241 acgaagatct ttatgcgtat ggatgaatct attttacgtc atatagaagg attagtgggt
      301 aaatcaatga cgaactcaga attagaatcc attcctcaac aaaatcaagg agacgctgtg
      361 atcaattttg gctcaaaaga aaccattcgt gttcatttta gtccgaacaa acgtcaatta
      421 aaattgtttg atggaggaaa ataatggaaa accaaaatga aagtttaatc aaacagtatg
      481 ttaagcgtcg tgcaaagcgg cgcttatttt tgtgggtgtt tggtacttct gcaggtttga
      541 ttactatatt gatcactgtg tttgtgaccc tttttctaat acttgcggca ggttctattg
      601 ataattctga ttcaagtagt ggtggcgaag cttttacagg agaatattcg gaaggcttac
      661 ccatttataa agaaatcaaa ggaagaggcc ctttttctga tgagattgcg caatatgctg
      721 taggtgcagc agtgaagtat aaattattac caagtgtgat cctttcgcaa tacggttatg
      781 aatcagcgtt tggtacgtcg gcgtccgcaa gaaatgatct caattatttt gggattacgt
      841 ggtttgatgg gtgtctgttt cctaaaggaa ctgcgcgtgg aattggtggc attgaaggtg
      901 gctggtacat gaagtttccc aactcaaaag ctgccttctc ctattacggc tttatggtag
      961 ccacacaatc aaattttaat gcttgtgtcg gaaataaaag ccctggcgca agcttattga
     1021 tcttaggacg aggagggtat gccgccgcag gaattactga agacagtgcc tattataaaa
     1081 attgtatgtc tattattaat acaaataaat tgatggagta cgatgagttt gcgattaaac
     1141 actggagaga aggcggcgga actggtggta cgattacagg aagctggggc aatccattcc
     1201 caggaagtag cttagataaa aattcgttca gtggaggaca actttttggg aaaaatccag
     1261 gaggagaatt ccgacctaac gggttccatg atggactaga ctttggttca gtcgatcatc
     1321 caggaagtga gattcatgcg gttcatggcg gaaaagtcgt gtacgttggc aatcctggta
     1381 tttcaggttt gggtgcgtgt gtgatcgtga ttaattacga tggcttgaat atggtgtatc
     1441 aagaatttgc aaatagtaca ggaaattctc gagtgaaagt aggcgatcaa gtgaaagttg
     1501 gtcaagtaat tgggatacga gatacagcac acttgcattt aggatttact cgaatggatt
     1561 ggcgtcaagc acaaggacat gcattcattg atgatggtac atggatcgat ccgttaccat
     1621 ttttgaatag cagcaaaaaa tagatcagga gaaaaaatat ggaaaataaa accttaaaaa
     1681 tcgtcttaac agctgcaatt agcgttagtt taatcggcaa tattgcgttg ttttggcagc
     1741 ttaaagaaga acaagagaca aatacctata aaattgaaga agtggctaaa aacgcgtctg
     1801 ataagctcaa aaaaaattct tctgaggcac aggcgaagat cgacaagtta aatcaaacca
     1861 tcaatgagaa aaaccaagaa atcgatcagc tgaagcaaca agatggcaca aaagcaaaag
     1921 aggaagtaac tgaagcacaa agaaagacgg cagaagagtt cggtcaattg gccattgata
     1981 aatcattaag cagaaatgaa ttaacggaaa aactaaaaga tgtcgcaacc caagaagtga
     2041 tcgacaaatt aagtcctgca gacgatgatc accaacatga cgactacgga agttactctt
     2101 ttacattagg tgacgtgcaa acttacgctc aaacaagcag tgtaaaagag gaacaaaatt
     2161 ttgtcgtatt tgttgattat acaatcggca atcctcaatt taaagatgtc aaaccacaaa
     2221 aaataaaagg tggattaact gtcactgaaa aacaagtaga tggtcaatgg aaagtcacag
     2281 actttagtta tttcactcgt taggaggaag aaaatgagta agaaaaaagg agcaagacaa
     2341 cgttttaaaa aacgaaaaag ttatcttaga tggctgggga tctttatgat tctcggcttt
     2401 ttgattcttg ctagtccgat ttacacacat aaaaaggtag acataccaga tgaagtaagc
     2461 acgaacgcat ttttaaacac gaaggaactg acgatggttt caaaagaaaa aggagcgaac
     2521 cagcaattag tttttgaatt tgcgatcgac gatgaagatc agagcttatt aaaagaacta
     2581 gctaatctta attatcgtgt agaagtaaag acagctaaag gggattatca agcaataaaa
     2641 gccaaagtga tcaaggtgtc tgatgattat tttgtagtga agttagcaca tgtaccagaa
     2701 gaatatatcg ccatgcgttt aaccattatt cctgaaaaaa ttgatccaaa agtggatatg
     2761 caagaaccac aagatctgat ttattacgtt cacgaagata aggttaaaga tcaagtgaaa
     2821 gatgaagatt atgaacaaca tgcgatcaat tacaaagtga aaggatacaa aaaagaacaa
     2881 aaagcagcac aaaaacaaat ggaatccttc caagcaacca ttgatttgaa tgaagaatta
     2941 gtgaagaagc taaaagatca attgccttat caagtcgcag atgatcagga aaatactgaa
     3001 aacaagatta atagctacca gcaagaaatt gaaacatcga aaacgcaaat gaaagatcaa
     3061 gaagagatca ttcaaaaact tcaagaaaaa attgatcgta tgacaaaaga aaagatttag
     3121 aaggacaggt ggagtgaaaa aatgaagcga acaaacttgg ctgacaaaga tactttcgct
     3181 gagcagaaag tattgattaa agcctatctc aaagttgtaa aagctaaaga aatatgtcga
     3241 gaagtgaatt tatctaatac aacaatatct gagttgaaga atggtcgaaa gaatttagat
     3301 actttaaaat tcagatcatt tgaagctcta tatgtagctg ctaaaaaata ttttacagct
     3361 gataacaaat aaaaaacagg agtattttat gtgaaaaaag tatataaaaa atgcttatga
     3421 atcagctata tcaccttaac catttgttaa tgagatggga gaaaacatta accacgattc
     3481 taacgcaaac atcaagcaca taaaacattt aacactcctc ctttctggct gaagatttca
     3541 accaaacagg aagacagcgt atcaattata gcatacactt tttcttaaat tcatttttca
     3601 tatgacaaaa tatttccttc taatcgacaa agttagaagg attttttatt gtctaaatac
     3661 acaaataacc ttaatttata aagagcataa ggaaacgtgg gaacactttt taaaaaaagt
     3721 gttccaatag gctgtgccta ttacgtttct caaaaataat tgtgggaaca aaatatttaa
     3781 aaataggata gtgaaaggat agcaaaggat agtaaaagga tagaagcagg atagcgaaaa
     3841 ggataggctc cttttcgcta tcctttttaa attggaggaa ttaatatgga agtaagaata
     3901 agaaatgtag atgagaaaat cgtaagagaa attgatcgaa gatgtgacga actaagtaac
     3961 cgaacgggta ataaatggag tcgtaacgat tatttaaagc tactcgttga aaatgatttt
     4021 gatcgtcctt tgatggaata taaacaagat aaatttgatc aattattaaa tcagttaata
     4081 gataaatttt cttttgttca aagtcataat acaaaagtat tagaagaata tatttgtcag
     4141 aataatcaaa ttatcgaact tttaattgaa caaagtagag gaggagaagt ttaacatggc
     4201 caaagttata gacaagcata tttattttta tgaaacacat atagatgttc tagatgaaat
     4261 tattgcaact catgcagagg ttaaaaacta tagtgaagcc gttcggtttc tatgtatgaa
     4321 ttatgattca gaagtggaga aaaaagtaaa ttccaatcaa gcaaagttga atgcaatggg
     4381 aaaagaaatt tctattttaa ccgaaatggt ttcagagttt gcggatctcc atttgaaaga
     4441 tacagggatt ttaattggta caaattcaac tgtttaccaa gaagcaaaag agcgtgtgga
     4501 aggcaagata aaagcaaatc aaacgaagaa atattctcct aagataaaga aaacaataag
     4561 cgaatcagtg actacaaaaa gtgaagtatt tgatccaaca aggttcttaa aacgataaaa
     4621 attagaagga gaatgtgatg agtaaatcac ctgcagtcat tctcacttgt caatttacct
     4681 tgcccaataa aaaatctttt tcaacataca ttgattatat gacaagagaa aaagcgctgg
     4741 aagaaaagga acgacgtacg cccgaggaag aacaggaact gcgtctaatc aagaatgctt
     4801 tagaggattt ttatattcct gaaggagaaa ctttttcgga gagtaagacg ggtaaagaat
     4861 tcagcgaaac gtcgaatgaa gcgcaatcgt tgatgaaaca tggaatcaat tttgacaagt
     4921 tagaagaaca agattttacc aaatatcttt cttatatgac acgtcactat gcgttagaac
     4981 aaaagaaagt actgacgcat agtgaacaaa aagaatacca acgcttgaac caagcaataa
     5041 aaaaatatca aacagagcca cacaaaaaag cttcaggaaa tcttcctgga gttttttcta
     5101 tggcttcaga cgaagtgaaa ggaagtgatc tgaaggagat caagcaaacc ttccaaagag
     5161 gacaacaaaa aggctcaatc atttatcaag atgttgtctc tcatgatcat tcgtatcttg
     5221 aaaaaatagg attgtacgat cccaaaacag atactttaga tgaagaaggt ttaaaagcag
     5281 ctggaagaaa aatgatggag acattgttcg agaaagagca actgaatgaa acaggctact
     5341 ggatggcaac gattcaccga aataccaaac atatccatat tcattttgca gttgttgaaa
     5401 aaaaaaatac gcgtaaacca tacactgaga ttgaaaatgg tgtgagttat atcgtaccga
     5461 aagggaagag aaggcaagca acattagacg aaatgaagac taattatgta catgagttag
     5521 aacgtttttc ttatgaaaaa aatcgaatgg gtatggagaa acgaaattta ttgacacgga
     5581 aaagtgattt gcgtaacacc ttaaccaaag tagtgaaaga gccagtacgt tatgatcgac
     5641 acgcaatgag cttattaact gaagtatata aaaacttacc taaaaagcgt tcggaatggc
     5701 attacgggga tgaaaatcga accaaacttt caccatacac aagagagaaa ctcgatgagt
     5761 taacccaata tgtgttaaca aaagaacctg gatatcaaga atatatacag atttcaaaag
     5821 cattgaaaga agaagcaaaa agtctttatg gggaaagcaa gagagaatca aaggatgcag
     5881 aaaaaaatgc tctctttgat ttaaaaaagc gcacaggaaa tgccattcta acagaactga
     5941 agaaacagga tagtcaaata aaacctttaa tagaaaggat ggatcagatg caatctattt
     6001 acaatgaacg atcctttcga acacttaaac agttgccaac gaatgaatac aaatatagtt
     6061 acgaagaatt catgaagcgc aggaaacaat tccaacaaag agttgtcacg caacggagtt
     6121 tgcgtcaatt aaatcgaacg attaatgccc atgaagaaaa ataccacgca agtaaagcat
     6181 acgaagagca acaacgaaga attcaaatgg aacaagaaag acagtaggag gaatagcaat
     6241 gaaacaatat ttagatcaat ggaaagttat agaaggatca ttaagagaag aacgaatcga
     6301 acaacttccc gattgtttag aaaaagagca tttgtttcag ataagagaaa tgttgataaa
     6361 cgaacagttt gatccaaatc aatttttagt cgttgagtac ccagctactg gtgtgtactg
     6421 ttgtaatcat gtgaagggtg aaaaatattt tatcattcaa gaatatgagg gcaagttagc
     6481 gccttattat actacttggg aaatgaatga agaggggatc aataacttcc cgtgtaaaag
     6541 cattgaagag tctatttcac tcacagaatg ttagttgtta agtgaataaa agaagtaaaa
     6601 gagtcctgaa cgtgattgtc caggactctt ttttttcact gaattgtttt ccgccaattc
     6661 attgagtggt gcgatttccg tctacattat atcaaaagaa aggaggaaga agaaatggct
     6721 tattcaacga ttggagttgt tgttgaaaaa agcagagaca atcttgtttt tgtgacagaa
     6781 attcaaacag gcagagcttt tgtagtcaca gacaaagcgg caaaagcata tcaaagtggc
     6841 gatattttaa cgttaaatct gactacgaag acgttcgtcg atgcggcaga agattatcca
     6901 tt
//
LOCUS       DADQDV010000108         6871 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.111, whole genome shotgun sequence.
ACCESSION   DADQDV010000108 DADQDV010000000
VERSION     DADQDV010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6871)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6871)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6871
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.111"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            105..995
                     /locus_tag="J8S10_002747"
     CDS             105..995
                     /locus_tag="J8S10_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HAZ9631305.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(1068..1892)
                     /gene="nadE"
                     /locus_tag="J8S10_002748"
     CDS             complement(1068..1892)
                     /gene="nadE"
                     /locus_tag="J8S10_002748"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HAZ9631306.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(1904..3376)
                     /locus_tag="J8S10_002749"
     CDS             complement(1904..3376)
                     /locus_tag="J8S10_002749"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HAZ9631307.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(4013..4375)
                     /locus_tag="J8S10_002750"
     CDS             complement(4013..4375)
                     /locus_tag="J8S10_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HAZ9631308.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            4598..5350
                     /locus_tag="J8S10_002751"
     CDS             4598..5350
                     /locus_tag="J8S10_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAZ9631309.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(5490..6413)
                     /locus_tag="J8S10_002752"
     CDS             complement(5490..6413)
                     /locus_tag="J8S10_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAZ9631310.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(6428..6700)
                     /locus_tag="J8S10_002753"
     CDS             complement(6428..6700)
                     /locus_tag="J8S10_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631311.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT         2117 a         1357 c         1163 g         2234 t
ORIGIN      
        1 ttaattaacc aaaatattaa taatgattaa aacaaataat ttaatataac ttttattaac
       61 aaatatgtta atatataaga aaaacctttt aagaggtgat atatatgcaa ctacaaataa
      121 acgaagaatc cttaccggta tatgaagcat tagctagtaa aacaaggatc aagatcatcc
      181 agctactttc caaaaaaaag atgaatgtca aagatttggc aaaagaactt ggagtgagca
      241 gtgctatcac gacgatgcac gtgaaaaagc tagaggaagc aaacatcatc aaaacagaaa
      301 aagtaggaca acaaaaaatt tcgagccttc gtgtcgataa aatcgatatc agttttccag
      361 aaaaaatatt caatgctttt gatacgaaag aaacatcgat acctattggt cactatacaa
      421 attatgcaat tgaaccaaca tgcggtttag ctacgatcca tgattttatc gggaaagtgg
      481 atgaaccacg ctattttatg gatcctcgaa ggatggatgc ccgcattctc tggtttacca
      541 gcggatttgt cgagtatcag gcacctaatt ttttaaatac agaggataca ttggagatgt
      601 tggaagtttc tgtggaaatt tcttctgaat ttcctttttc aaatgacaat tggccttcag
      661 atatcacttt cagcctaaat ggtgtggagc taggaacatg gacgagccct ggagattttg
      721 ctgatatccg cggtaaatat acgcctgatt ggtatccaga taatcttaat caatacggct
      781 tgctgaagac gatccgaatt accaaacact tgacgaatat gaatggagaa cccttgtcaa
      841 acatcacgat caacgacatc cctaaagagc aagacacttg gcatttgcga atcgaagtga
      901 aagacgatgc caaacatgtg gggggctgta ctttatttgg taaaggattc ggtaattacg
      961 atcaggatat caaattaaaa gtttactaca gctgatattt ttcttttcta ttttataaaa
     1021 caaaaacagc caatccctat gaagggacgg ctgtttttgc tttattgtta tttccagaaa
     1081 tcatccaaaa cggaaattgg caaatgtcgt ttatgttgtg tcttgttcca ccatgcttcg
     1141 attttttctt gtgcttgagc gggaacttct tttccttcta gataatcatc aatttcatta
     1201 tatgtgacac ctagtgcgac ttcatctgca atcattggtt tcccatcttc aagatctgca
     1261 gtcggaattt ttgtgtataa tttttccggt gcattcaatg cttgaagcaa ttgtttccct
     1321 tgtcgtttgt ccaaacggaa taatggcaaa atgtcggctc caccatcacc aaatttcgtg
     1381 aagaatccag taatgttttc tgcagcatga tctgtcccta atacggctcc tgctctttct
     1441 ccagctacgg catattgcgt aatcatacgt tgacgtgctt tgatatttcc tttgttaaaa
     1501 tcgctgattc ccacacctgc ttcgcttaat acttgtactt gtgcatcaac agctggtttg
     1561 atatttactc gcagactaac atcgggctgg ataaagtcaa gagcagcttt tgcatcttct
     1621 tcatctgctt gttcaccata aggaagacga acagcgataa attgatagtt ttcatctttt
     1681 gtttcttcac gcatttcttc catcgttagt tgcgccaaac ggcctgctaa agtagaatct
     1741 tggccgccgc tgatacctag tacaaaagtt ttaagaaacg gatatttttt caaatatgct
     1801 ttcataaagt caatactttt acgtatttct tcttttggat caattgttgg tttgacacct
     1861 aattcattga taatttctgt ctgcaggctc atttattctc ctcctatgct tctgtatgaa
     1921 gttctgctac gctttttttc attcgttcca tgatagccat tttatggttc cagcattcag
     1981 tagacagatc gactgggtat ttttgcggat tcaagtctcg tttatactct tcccatagtg
     2041 aatctagatt ttcttttgta tattctttga tttcgtttag tgcaggtaat tcgtaaactc
     2101 tttttccttc gataaagata tcttgtaaaa ctgggcgagc tgtaaagtct cgaacagttt
     2161 tattgataaa cgtatgcact ggatggaaca tgaagatagc ttcttcttct cgagggtctt
     2221 catcccataa tgtcacgtag tctccttcag atttcccatc aaaatttcga gtgatgcgcc
     2281 acacttgttt tttccctgga gtagttactt tttctgcatt gcttgataac ttgatcgtat
     2341 ccatcatttt tccttcatca tcttcgatcg atactagctt gaatactgca ccaagggctg
     2401 gctgatcata ggctgtgatc aattttgtcc caacacccca tacatcaatt ttagcttttt
     2461 gcatctttaa attcaaaatc gttgcttcat ccaagtcatt cgaagcatag atttttgctt
     2521 ccgtaaatcc ggctgcatct aattgttccc gaacacgctt agatatatag gccatatctc
     2581 cactgtcgat gcgtacgcct tggaagttga ttttgtcacc taattctttc gccacgcgaa
     2641 tcgcacttgg cacacctgat ttcaacgtat cataagtgtc gactaagaac acgcagtctt
     2701 tatgggtttt agcgtaggcc ataaatgctt cataatcatt tccataagat tggactaacg
     2761 aatgagcatg ggtcccgcta gctggtatcc caaatatctt cccagcacgt acattgcttg
     2821 ttgcatctgc tccgccgata tatgccgctc tagttcccca gactgctgca tccagttctt
     2881 gtgcccgtct agttccaaat tccaatagtg gatcttctcc gatgacagat ttgatacgag
     2941 ctgcttttgt cgcgatcaac gtttggaaat tgaccatatt caacagtgct gtttctacta
     3001 attggcagtg cgctaaaggc ccttccactt ggattaatgg ttcatttgca aaaactagtt
     3061 ctccttcacg agcagaacga actgttgctt taaattcaaa attttgtaaa tactccaaaa
     3121 aaccttcagg atagacttct aatccacgca agtaagcaat atcggaatca ttgaacgtca
     3181 gattctctaa ataattgact aaccgttcca atcctgcaaa aaccgcgtat ccgtggttaa
     3241 aaggcatttc tcgaaagtaa cattcaaaaa cagcatgtaa atcagctcga cctaattccc
     3301 agtatgtctg catcatattg atttgatata gatccgtatg cagcgtcaaa ctgtcgtctg
     3361 ggtaagtatt attcatcttg tattactcct cttggcaagt tttcatttcc tacccattat
     3421 aacaaaaaaa attaatagga aaagaaatct tccatttttt ctgaaaaagc acatgtttta
     3481 cggatatttc ttgctaaaaa tgaactccat ctgctaaaac tatcctttct tattggtatt
     3541 taacctaaac gagaaagaat acttatttta ttcaatgtat ccgagacacg aagaaattag
     3601 cgttttctat ttttcttact tgataaaata agtagatttt cctactacaa tcgtagccgt
     3661 taagataccg atgattgaac aaatataacc aaatgtctct acaacataat caatggcaaa
     3721 agtttttgaa gcaataatac gtctttcctt ttttgcttct tatccccaaa gaaacggata
     3781 taacttatta tgtattgaat ttttttggaa aggcgaatta tgacaagata taccttgcgt
     3841 tgaaaaaact cgcggaaaaa atatcacacg tttttaaaaa gatacaaagt aagaaagcag
     3901 ctgtcaatag aatggaaaca aaaatggcga gacatcaatc agtctcgcct tgttttttat
     3961 tgtatacatt agatatggag caggttacca taaagatgat tattagtcgt tattaaatag
     4021 aatccttcgt atttttttgt tctatcacta caatatcttt atttggacgt ttgaattgta
     4081 ttccggcacg ttctagctcc tgtttcactc ctacatggac tttgacatct tctcgtgtca
     4141 tttttaaaac gtgatgaatc gcatagtcga tttcttgcct tgtgattttt ttcttcgtat
     4201 tgatcatcac gacttgcttt ttatcatatg tgtctaccaa tagcagttgt gttcgatcta
     4261 acgaaaataa tttgtaataa ttaatagccg tattcccaaa aaagaattcc actactttag
     4321 gataaaatgt cttaatattt aaattactat tcacaggtgt ttcgattagc ttcatctcat
     4381 tcctcttttc tatatagtcg atttagatcc aatcttaagt tatgttacca tctttcctag
     4441 cattaaggaa tcggttacaa ttgaaccttt aaagacaaaa ggatttacct tttatcactt
     4501 aatagtataa cataatttcg tgagaaaaaa atacaatttt ttcttgacca tctcgttacg
     4561 taaaggatta tgcttacatt tgtcaggagg aaaaataatg gagtacacaa taaagaaaat
     4621 gtcagagata tcaggagtca gtccgagaac cttgcgcttt tatgatgaga ttggactgct
     4681 aaaaccagct aggatcaatt cttcaggtta tcggatttat ggcaaaaaag aagtcgatcg
     4741 tctgcaacac atcttatttt atcgaacaat ggcattcaag ttggatgata tccaagaggt
     4801 cttagacaat ccatcttttg accaccagaa agctttaatc aagcatcagc aaatgttgct
     4861 ggaaaaacgg gcacaaatcg ataccctctt gacaactgtc caacagacac ttgatatgta
     4921 cgaaggagga agaaaaatga gtgacaaaga aaaatttgaa gggtttaaac aacaaaagtt
     4981 gaaagaaaat gaagaatcct atggacaaga gattcgacaa aaatacggaa aaaaaaaggt
     5041 tacagcatcc aatgaaaaat ggatgaatat ggataaagaa acgtatgaag aaatgcaaac
     5101 tgttgaaaag cagatgttat ttgatctcac tctttactta aaagaaccag aagatgaaag
     5161 cttagcagac cgtatcttcc aagctcataa gaagtggttc tcttacagct ggcctgaata
     5221 tcagccaaaa gcgcataaag gactaggaat gatgtacgaa gccgatgaac ggttcactgc
     5281 atattatgac gagcgaagtg gtcatggtgc agcaaaagct ttaaatgaaa ttatccaaaa
     5341 aaaggcgtaa tcttttacat gatccaacaa aaaagtacac gtaaaatgac ctaataacaa
     5401 aacagcagac acccaagtta gatttttatg ctaacttttg gtgtctgctc cattctttca
     5461 caagtttttt catcctactt taaatatatt catcgttgaa taaacgtata aggtattttc
     5521 actttatcct ttttttctgt aagaaacaat tgaaatgcca tttctccgca agcttccaga
     5581 tggtggtcga tggttgggaa accaagaagc tcgctgatca gcaaattatc gcgtccaatc
     5641 accactggtg tcttatcttg cagatagctt tgcaagatgc ctgctgcaac catatccgaa
     5701 tttgtaaaga caccatcaac tccaagctct ttaaaaaaga agcctgcttg ttttcctttc
     5761 tctgcatcta tacaatccca aaaaacaagt gattcatcaa aagatggaaa aagttgatga
     5821 catagctgca aagtgatttt tgagttataa cttagcctgc cacttcgccc caacgtgatg
     5881 cccaattgct ttataccttg ctgcttcaaa taagtaagac cttctgtaat tgattgttct
     5941 cgatcaataa agacacagct tgcctgtttt cccttgattt cttcacaaaa aactagaggt
     6001 ccatattttt gatatgccaa taaatcatct agtgtattgg cacgagacgt aatgatcaat
     6061 ccatcgaaag ctttagctgc aaattcttca agataccttc gctctttttc tttatgatag
     6121 cccgtcggta aaagtgtcac tttgtaatca taatcaaacg ctgcttcaat gatcccactg
     6181 atcaactgat caaaatacgg atgattggta taaggcagaa tcactccaat gcttttcgtt
     6241 tttccataac ttaactgtct ggcatttgca ttagggatat aatcgacttc tttcatgacc
     6301 gcaagtattt ctttcctttt ttcctcatct acatatggat gtccattgat tacacgtgaa
     6361 atagtagaaa ctgaataacc tgtgagcttt gcgatatctc gaatgtttgc cactgctgct
     6421 tcgccaccta tacaaaaaga ttttcttgta aatagtctac cacagctgga ccgcattcaa
     6481 aaaactgata catttttcct tcatgcgaaa aactgatccg ctgcccgccc caatatatat
     6541 cttttgtcaa attttcgatt tcattcattg gtatttcttt tactatattc ctattcaacc
     6601 cttgaaaact gtacaacgtt aatacggatc ccttgaactc gacaaacgca taaaaataat
     6661 tgttcgttgt gccatctgtt atctctacat aagtattcat tgcaagccct ccttttgata
     6721 ctttgagtat agtgtatgaa acgcgtctca tagcaaggag tttgttttgc caaagaaaag
     6781 ttttattcct ctttcattat taccaaagtc tcttatttta aattgaatac attataatga
     6841 tactgtaaat atatctttat tattagtgaa t
//
LOCUS       DADQDV010000109         6869 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.112, whole genome shotgun sequence.
ACCESSION   DADQDV010000109 DADQDV010000000
VERSION     DADQDV010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6869)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6869)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6869
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.112"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..227
                     /locus_tag="J8S10_002754"
     CDS             <1..227
                     /locus_tag="J8S10_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HAZ9631312.1"
                     /translation="KTTEFDILHALMSTPNKVFSRSDLIEKVKGIEFDGLDRSIDSHI
                     KNLRHKIENDAKSPMYILTVHGTGYRFGGH"
     gene            227..574
                     /locus_tag="J8S10_002755"
     CDS             227..574
                     /locus_tag="J8S10_002755"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631313.1"
                     /translation="MRKRTIKTQLAVSFLAIATLIIGSISLVALSLMNNHFSKYVEER
                     QEDLLNQYVYTIDLLWLNSGETWNSEELAALSEKVLENNIYFSIEDEQGNMVWELTGK
                     DLKSAQEKLKKMH"
     gene            571..1620
                     /locus_tag="J8S10_002756"
     CDS             571..1620
                     /locus_tag="J8S10_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAZ9631314.1"
                     /translation="MKVSEKNSVKLDETIEVKKKLINDGNEFGKVTFYYFGPFAYTEH
                     DALFISSMKQSLMYVAIAALLVSFILASWISARLGLPLKHVSDFTHKLTRGEYADKIP
                     QETSIIEINSLIDSLNDLSNQLEKQHGLRKRLTTDISHELRTPLATLKGNVEGMIDGV
                     WKITPERLQSCYDEIDRLTRLIGNIEIINKIEAKYDHLNKTEFNIYKLIESVIENFAS
                     KIESKNLHVEIQGDNINISADKDKMNQVVINLLNNAIKFTQKEGTIKFSISKNKDHVL
                     LIVEDNGIGIEKDQQLHIFDRFYMADPSRSRALGGQGIGLAIVKSVIEAHKGSITVKS
                     KLGLGTKFVIKLPFQ"
     gene            1635..1841
                     /locus_tag="J8S10_002757"
     CDS             1635..1841
                     /locus_tag="J8S10_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631315.1"
                     /translation="MFQKQIKIAKLVCECWAKKIFFQLISIDSVEKVHLDILSNSVVI
                     FSKKDLSIATIKKEVFGLQIYEMT"
     gene            1862..2458
                     /locus_tag="J8S10_002758"
     CDS             1862..2458
                     /locus_tag="J8S10_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdhK family protein"
                     /protein_id="HAZ9631316.1"
                     /translation="MKTVKKMTKLVFASLGIIVFLGACSNQSESNNSNSTNEESTSTA
                     SSEMNSMEGMNHEGMVPSSMKDAANPKFPVGSNVILLGDHMEGMKGANAQVVGAFDTT
                     MYEVSYEPKTGGPMVNNHRWVVQEELKDTETVANEGDTVILNADHMDGMMGAEAKVDK
                     SITGTVYVVNYTPTDGQEEVKNHMWVTEDEMEYDENNE"
     gene            3410..4009
                     /locus_tag="J8S10_002759"
     CDS             3410..4009
                     /locus_tag="J8S10_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAZ9631317.1"
                     /translation="MKSVEPIRDKKKIDAMKAILASGKYGQRNLVLFSIGINTAYRIS
                     DLRQLKLRDVLEISRGRVIVKERLAMKEQKTAKHNSVFISNKLRKVILDYVQSEFPEQ
                     LQAQDFSKYLFPSRKGADTPLTRQSLWRIIHEAGTAVGLKEIGPHSMRKTFGYFLYKQ
                     GTKTEIIQSLLNHSSQRETLRYIGITQEDKDTAVKSLDL"
     gene            4058..4774
                     /locus_tag="J8S10_002760"
     CDS             4058..4774
                     /locus_tag="J8S10_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HAZ9631318.1"
                     /translation="MNEEKQPNFPDKYHLSRKESVYLLKKNIVELVYNAGKFEGLNTT
                     LLQTEGIIKYNRANNVAVDDVLTVVNLKRGFEMLLNDVQEPLLETSKRINRIVAAEDA
                     LFPGEIRTGGVELSTIQGRYVPPMLTEDEVNNQYGEIMNQEISDTEKALRLFLFISKN
                     QIFWNGNVGTALLIANKIMFSNGLGLLSIPENVFMKFNELLSKYCNSNLLVNESNIIS
                     FLYEQCIFGINYLKIIQHTI"
     gene            4788..5567
                     /locus_tag="J8S10_002761"
     CDS             4788..5567
                     /locus_tag="J8S10_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002396205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HAZ9631319.1"
                     /translation="MMTIDEAKQLATYFSVGSAGYILDFTNVTWNIFTKKIVGIEIQN
                     HYGGSKGVSFQKFLLDDQFDDSLKNRLIQSLKGIMDRDKKYESTEMNPIVQLLFEEVF
                     KEDTSTALRKMKFSSEIDLLYIRQLPIRIQTDIKNKDFDSVLTKANTLIDEVLKFIIE
                     NTEGPSVNINLFKSKELRKEVFGRLNIKTEKDMDNRIKALVGALNTLSDKILEMRNSQ
                     GDAHAHGSNRIVIKEEEAILVANSSMVLCEYVFTKYKGLNR"
     gene            5650..6006
                     /locus_tag="J8S10_002762"
     CDS             5650..6006
                     /locus_tag="J8S10_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAZ9631320.1"
                     /translation="MEKISFETFKRPNGHDEFLEWLETLPKKDSAKLLRTIEETEKNG
                     MLVAQRLKWVKKLDTNLYELRSKVGSNIQRAIYFHVDNGRYVITHGFTKKTEKTPITE
                     LKHAKELREEWFTNDD"
     gene            5996..6262
                     /locus_tag="J8S10_002763"
     CDS             5996..6262
                     /locus_tag="J8S10_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAZ9631321.1"
                     /translation="MMIKKLIEEKKKDKDFAEAYDREGRKLETAVALYHAREEAGLTQ
                     AELAQKAHTTQSTIARIERGDNVSFDKLDDIARALGKKLVVEFA"
     gene            6421..6699
                     /locus_tag="J8S10_002764"
     CDS             6421..6699
                     /locus_tag="J8S10_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631322.1"
                     /translation="MKTINLIKVFIASPGDIAAKRNEVEETIYRWNIENTDNTKVILM
                     PIRWETNAIPTYVNNSSGQSVINKQIVENRVLLQSFKNKISFCIISSF"
     gene            complement(6696..>6869)
                     /locus_tag="J8S10_002765"
     CDS             complement(6696..>6869)
                     /locus_tag="J8S10_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010868911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HAZ9631323.1"
                     /translation="HRSIKRRHKLYQSLRTASTTIKGMETIRGIYKKSRKEGTLFGFS
                     VCTEIRILLGIPA"
BASE COUNT         2527 a          957 c         1333 g         2052 t
ORIGIN      
        1 ttaaaacaac tgaatttgat attctacacg ctctaatgtc cacacctaat aaagtctttt
       61 ctcgtagtga tttgatagag aaagttaagg gaatagaatt tgatggacta gataggagca
      121 tcgattctca tataaaaaac ttaagacata aaattgagaa tgatgctaaa tcacctatgt
      181 atattttgac agtccatggt acaggataca gatttggtgg ccactaatga gaaaaagaac
      241 gataaaaact caattagctg tttccttttt agcaatcgca acattaataa taggatcgat
      301 tagtttagtc gcattaagtt tgatgaacaa tcattttagt aaatacgtgg aagagcggca
      361 agaagatttg ttgaatcagt atgtatatac aattgattta ttgtggttaa atagtgggga
      421 aacatggaat agtgaagaac ttgcagcact atctgagaaa gtattagaga ataatattta
      481 tttttctata gaagacgaac aaggcaacat ggtttgggaa cttactggaa aagatttgaa
      541 gtcagcacag gagaaactga aaaaaatgca ttgaaagttt ctgagaaaaa cagtgtgaaa
      601 ctagacgaaa caatagaagt gaaaaagaag ttaattaatg atggaaacga gtttggaaaa
      661 gtaacgtttt attatttcgg accttttgct tatacagagc acgatgcctt gtttatctcc
      721 agtatgaaac aaagtttaat gtatgttgca attgcagctc ttcttgtatc attcatactt
      781 gcttcgtgga tctctgctag attaggattg ccactaaagc atgtaagcga ttttacacat
      841 aaattaactc gtggggaata tgctgataaa atcccacaag aaacttcaat tattgaaata
      901 aattccttaa ttgattccct aaatgattta agtaatcagt tggagaaaca gcatgggctt
      961 cgaaaaagat taactaccga tatttcacat gaattaagaa ctccattagc tacgcttaaa
     1021 ggcaatgtgg aaggaatgat tgacggagtc tggaaaataa ctcccgagcg cctacaatct
     1081 tgttatgacg aaatagatcg tctaactcgt ttaattggaa atatagaaat aatcaacaaa
     1141 attgaagcaa aatatgatca tttaaataaa actgagttta acatatataa gttgattgaa
     1201 tccgttattg aaaatttcgc cagcaaaatt gagtcaaaaa accttcatgt tgaaatccaa
     1261 ggggataaca tcaatatatc tgcagataaa gataaaatga accaagttgt tatcaatctt
     1321 ttgaataatg ctattaaatt tacgcaaaag gagggaacca ttaagttttc tataagtaaa
     1381 aataaagacc atgttctttt aattgttgaa gacaacggca tcggtataga aaaagatcag
     1441 caacttcata tttttgatag attttatatg gctgacccct ccagaagtag agctttaggg
     1501 gggcaaggta tcggattagc tattgtaaag agcgttattg aagcgcataa aggtagtata
     1561 actgtaaaaa gtaaattagg tctaggaact aaatttgtta taaagttacc atttcaataa
     1621 aggaggagag ttatttgttt caaaaacaga taaaaattgc taaactagta tgtgaatgtt
     1681 gggcaaaaaa aatatttttt caactgattt cgatagatag tgtcgaaaaa gttcatttag
     1741 atatcttatc aaattctgta gtaatctttt ctaagaagga cttatcaata gctacaatta
     1801 aaaaagaagt ttttggatta caaatttatg agatgaccta aatgtgatta attaaaggag
     1861 gatgaagaca gtgaaaaaga tgacaaaatt agtatttgca agtcttggaa ttattgtatt
     1921 tttaggagcg tgtagcaatc aaagtgaatc gaataattct aatagcacaa acgaggaatc
     1981 gacttctaca gcgtctagtg aaatgaatag tatggaggga atgaatcacg aaggtatggt
     2041 tccttcttca atgaaagatg ctgcgaaccc taaattcccg gtgggaagta atgttatact
     2101 gctaggcgat catatggaag ggatgaaagg tgcaaatgct caagttgtag gggcctttga
     2161 tactacaatg tatgaagtaa gctatgagcc aaaaactggg ggaccaatgg ttaacaatca
     2221 tcgatgggta gtacaagaag agttaaaaga tactgagact gtagcaaatg agggcgatac
     2281 tgttatcttg aatgccgatc acatggatgg gatgatggga gctgaagcaa aagtagataa
     2341 atctattaca ggaactgttt acgttgttaa ttacactcca accgatggtc aagaagaagt
     2401 taagaatcat atgtgggtaa ctgaagatga gatggaatat gacgaaaata atgagtaatt
     2461 ttatatacta aaccaacaag ctggtacatg gtcttcgtat tctcaacatg aggaatatga
     2521 gctctttgtt aataaggact gatgagttgt gcaaaatcaa atctgggtca gaacgaacct
     2581 cattctggct cagatttttg gctcttcgac atttagtgct ggtagagaga caactgaaaa
     2641 tttagtcata accagttagg cagagtgctt aactggtttt tgttcgcatt tattattctt
     2701 ttgatattgg ctgcttgccc ttcaatttta tttggtttct taatcaactc ttcatataac
     2761 cccaaatcat atattaatga ggtgcctcct attcctataa atctatctct tctttaatag
     2821 tatgagaaaa gtctactctt gtagatttaa attgtcaaca aaaaatttac agatgtaaat
     2881 gataagttga atagagaaag ataaattatt tttttggtat tcatataagg ttaattatgt
     2941 attatcacaa aatgattgtt gtcgaataac taaaagtgtc aaaacaatga tgaaatcatt
     3001 tagttcttat aaattagaca agagaaaata aatattccat atctacttta ttggatccat
     3061 aacatgacta aattctgaat actttttaaa gcttatcatt tggtaaaact gaatataagt
     3121 taattatata gactgaaaat tttgaatttt cagaatagaa taacttaaaa gtactgacaa
     3181 attttttaaa ggggcaatat taatgttctg agataatcaa atcttaccga aaatatcaaa
     3241 agtccaatgt gacacaattg gattttgtca cattcgttaa aatcgctcca tccttagagg
     3301 ctctaatagg aaatcacttt tcttttagcg ccttttttct atagcttgtt taaatgtgac
     3361 ttattatctg ttataatcgt attaagtaac atttgagagg tgtctaaaaa tgaaaagcgt
     3421 ggaaccgatt cgcgacaaaa aaaagatcga tgccatgaag gccattttgg cttccggaaa
     3481 atatgggcaa cgaaatttgg tgcttttttc gatcgggatc aatacagcct atcgaatctc
     3541 cgatttaaga cagttaaaat taagggatgt gctagaaatt tcccgtgggc gggtgatcgt
     3601 caaagaacgt ctggccatga aggaacaaaa aacggccaaa cacaattcgg tcttcatttc
     3661 gaacaaattg cgaaaagtga ttcttgatta tgttcaatcc gaatttcctg agcagttgca
     3721 agcacaagac ttcagcaagt atttgtttcc aagtcgaaaa ggagcagata cgcctttgac
     3781 ccgacaaagc ctttggcgga tcattcatga agcaggaact gcagttgggt taaaagaaat
     3841 tggtccccat tcgatgcgta agacctttgg ctatttttta tacaagcaag gaaccaaaac
     3901 agagatcatt cagtcgctgc taaaccattc ttcacaacgg gagaccttac gctatattgg
     3961 aatcacccag gaagacaaag atactgcagt aaagagtttg gatttatgac agaataatgc
     4021 cctatataat agaaggaaaa attcaagagg tgagaaaatg aacgaagaaa agcagcctaa
     4081 ctttcctgat aaatatcact tatctcgcaa agagtctgtg tatttattga agaaaaacat
     4141 tgtagaactg gtgtataatg cggggaaatt tgaagggtta aatacaacgt tgttacaaac
     4201 agaagggatt attaagtata atcgggccaa caacgtggct gtagatgatg tcctgaccgt
     4261 cgttaactta aaaagaggct ttgaaatgct tttaaatgac gtacaggagc ccctgttaga
     4321 gacaagtaag cggattaatc ggatcgttgc agcagaggat gcgctttttc ccggtgaaat
     4381 acgaaccggt ggggtagaat tatcgacgat tcaaggaaga tatgtgccac caatgttaac
     4441 tgaagacgag gtaaacaatc aatatggtga gataatgaat caagagatat cagatacgga
     4501 aaaagccctg cgactgtttc tattcatttc gaaaaatcaa atattctgga atggtaatgt
     4561 gggtacagcc ttgttgattg cgaataagat tatgtttagc aacggtttag gactattatc
     4621 aatacccgaa aatgtattta tgaaatttaa cgaactttta tcaaagtatt gcaacagtaa
     4681 tctattagtc aatgagtcaa atattatatc atttttatat gaacagtgta tctttggtat
     4741 taattatttg aaaataatcc aacatacaat ttaagaggta taagtaaatg atgactatag
     4801 acgaagcaaa acaattagca acttattttt cagttggttc agcgggatat attttagact
     4861 ttactaatgt aacgtggaac atatttacaa agaaaatcgt agggattgaa atacaaaatc
     4921 attatggggg ctcaaaggga gtatcctttc aaaagtttct gcttgacgat caatttgatg
     4981 attcgttaaa gaatcggtta atccaatctt taaaaggtat tatggatcga gataaaaaat
     5041 atgaatctac tgaaatgaat cccatagttc agttgctttt tgaggaagta tttaaagaag
     5101 atacttcaac tgcattaaga aaaatgaaat tttcaagcga gattgattta ctttatattc
     5161 ggcagctacc cattaggatt caaacagata ttaaaaacaa ggattttgac tctgttttga
     5221 caaaagcaaa tactttaata gatgaagttc taaaatttat tattgaaaat accgaaggac
     5281 cgagtgttaa tattaattta tttaagtcaa aagaattaag aaaagaagta tttggccgcc
     5341 tcaatattaa aactgaaaaa gatatggata atagaatcaa agcccttgtt ggagcactca
     5401 atacattatc agataaaata ctcgaaatga gaaatagtca aggagatgct catgcacatg
     5461 gctcaaatag aatagtaatt aaggaagaag aagcaattct tgttgcaaat tcttctatgg
     5521 ttttgtgcga gtatgtgttt actaagtata aaggattaaa tagataataa aatgcatatt
     5581 ttatagtata caattcgaat ttttatgtta tatactataa tataaaatca atatatgata
     5641 taattgggta tggaaaaaat atcttttgaa acatttaaaa gacccaatgg tcatgatgaa
     5701 tttttagaat ggttggaaac attaccaaaa aaagatagtg cgaagctttt acgtacaata
     5761 gaagaaacag aaaagaatgg gatgctagta gctcaacggt tgaaatgggt gaaaaaatta
     5821 gacactaatt tgtacgaatt aagaagtaag gtaggatcaa acatccaaag agccatctat
     5881 ttccatgtgg acaatggaag gtatgtcatt actcacggat ttactaaaaa aacggagaaa
     5941 acaccaataa ctgaactcaa gcatgcaaaa gaacttagag aggagtggtt cacaaatgat
     6001 gattaaaaaa ttgattgaag aaaagaaaaa agataaagat tttgcagaag catatgaccg
     6061 tgaaggaaga aaactcgaaa ctgcggttgc tctttatcat gctcgggagg aagcagggct
     6121 aactcaagcg gagcttgcac aaaaagcaca tacaactcaa tctactattg ctcgaattga
     6181 gagaggggat aacgtatctt tcgataaact tgatgatatc gccagggcat taggtaaaaa
     6241 gctggtagta gaatttgctt aaaagcgagt tgaaaatata tctataatag gctcctaact
     6301 aatcaattag tttagtgggc ctttttttac tagatagata aaggttgtac tatagtgtaa
     6361 aagacaataa attttatact aaaattactt taaagagaac tagagagaaa ggtacaataa
     6421 atgaaaacca taaatcttat aaaagtattt atagcatcac caggtgatat agcagcaaaa
     6481 aggaatgaag tagaagaaac catatataga tggaatatag aaaatacaga taatacaaaa
     6541 gtgattttga tgcctatacg atgggaaact aatgcgattc ctacttatgt aaataatagc
     6601 tctgggcaaa gtgttattaa taaacaaatt gtagaaaata gggttctgct gcaaagtttt
     6661 aaaaataaaa tcagtttttg tattatttct tcattttaag ctggaattcc caataatatc
     6721 ctgatttcag tgcagactga aaagccgaag agagtgcctt cttttcggct tttcttgtag
     6781 attcctcgaa tggtttccat ccctttaatt gtggtggaag ctgtacgtag actttgatac
     6841 aatttatgtc gacgttttat cgatcgatg
//
LOCUS       DADQDV010000110         6840 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.113, whole genome shotgun sequence.
ACCESSION   DADQDV010000110 DADQDV010000000
VERSION     DADQDV010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6840)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6840)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6840
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.113"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(105..395)
                     /locus_tag="J8S10_002766"
     CDS             complement(105..395)
                     /locus_tag="J8S10_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HAZ9631324.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITR
                     QRRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
     gene            complement(531..710)
                     /locus_tag="J8S10_002767"
     CDS             complement(531..710)
                     /locus_tag="J8S10_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631325.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHNFRFYIFPLYI"
     gene            complement(707..1057)
                     /locus_tag="J8S10_002768"
     CDS             complement(707..1057)
                     /locus_tag="J8S10_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631326.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTE
                     EIAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIIGKILGSDELGIYVGKDKIHYDEIR
                     HIEFYQDNKWSRLE"
     gene            complement(1050..2375)
                     /locus_tag="J8S10_002769"
     CDS             complement(1050..2375)
                     /locus_tag="J8S10_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HAZ9631327.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSLNLFTTEGTRSQRRKKLAQMIQENIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFVAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRL
                     NQMGIMSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLHIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGNGGIKND"
     gene            2825..3439
                     /locus_tag="J8S10_002770"
     CDS             2825..3439
                     /locus_tag="J8S10_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAZ9631328.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQ
                     RRLVYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
     gene            complement(3604..4428)
                     /locus_tag="J8S10_002771"
     CDS             complement(3604..4428)
                     /locus_tag="J8S10_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631329.1"
                     /translation="MIERLKDFMISVWDVAMLADESNYTSSIYRLEDSNWIEISLELK
                     TLPNSVNYIIRDITSEAQQLVNYMHGHESIPFSLILLKRSKNISNTRDRFISIITACE
                     IGVKEFYQQEKPDLTLIFENLQSPPVDKLLGSMFKGYFNIEFPKEIRKEIKNFIEKRN
                     KLVHSPQGSKPTIEECFECYMAVLKTFNFFYKINDSFMYRDFYEESIELTPTEPNKSQ
                     ITLSKELERKVESQELAIGISITNVSTYKELYEAKSQDNKDFVENIDKEPTNTVGD"
     gene            complement(5066..5323)
                     /locus_tag="J8S10_002772"
     CDS             complement(5066..5323)
                     /locus_tag="J8S10_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HAZ9631330.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLG
                     KPEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
     gene            complement(5316..5585)
                     /locus_tag="J8S10_002773"
     CDS             complement(5316..5585)
                     /locus_tag="J8S10_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAZ9631331.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKR
                     DYDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
     gene            complement(5716..5895)
                     /locus_tag="J8S10_002774"
     CDS             complement(5716..5895)
                     /locus_tag="J8S10_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631332.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLL
                     IAQEKAGFEVPALKK"
     gene            complement(6276..>6840)
                     /locus_tag="J8S10_002775"
     CDS             complement(6276..>6840)
                     /locus_tag="J8S10_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631333.1"
                     /translation="EQLYLESETSQTKVTVSHNRLDVYKRRPETVKKGTELLRLETEK
                     YIMNVYLERSELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKDATIDD
                     YYLVFTRFLTCGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYT
                     YDDTEEIQNELDRKRMPYQRFERKKRQ"
BASE COUNT         2098 a         1299 c          997 g         2446 t
ORIGIN      
        1 ttgttactaa taattccctt cttatagtgc attttcttag aaaaaaacaa tattacgata
       61 tcatgatatt aagatatcgt aatattatac aattgtgatt gatattatat atgttttttt
      121 atttttttat catgtttaat cttgaaggaa tcatattctt tttctaaaga caggagcttt
      181 tcataaacat cagacatgtt taaactagag gccaggctta aatcataaac gaatgaagca
      241 ggtaatgatt ttattctacg ttgtcgggtt atccagcttg caaccgttcc ttgtgggtag
      301 gcatataact cacaaaattg ttctacagtg attcctaaat tcttgataat gtaaacattg
      361 atcgggtgcg agtaaacaaa tgtattgata gacatggtgc gtaagcctac tttcttttat
      421 tattgcgttt gcaataatag tttaacacac gcattattct agtatctact cctatttgta
      481 aaaacaaaaa aggattcata gagataactc tatagaatcc gtaaaatacc ttatatatat
      541 aacgggaaga tataaaacct aaaattatga taacctgctg cagcttctac atagaaagag
      601 aagcgctcaa caccaacctc atttatcaaa cgttggccat aaccccaaat ctcttctgat
      661 agctgatcaa aggttatata ctttagctca tattgctgga taatgttcat tctaatcgac
      721 tccatttatt atcctggtaa aattcgatat gacgtatttc gtcgtagtga attttgtctt
      781 ttccaacgta gatccccagc tcatcactac ctaagatctt gccaatgata tcttctggat
      841 agtatccttc agcgtttcgt tcttcttttt gaatagatac tgatctattt tttatgactg
      901 cagcgttcaa tacttccgca atctcttcag tcgtcatttg ttcttttgct aaattttgac
      961 tggttcgttg ttcattgtcg gcatcaattt cttcagtatg atcagataaa taaaaccctg
     1021 cccactttaa acgtccacga tcattgtaat caatcatttt taattccccc atttccgccc
     1081 gcatgaccac caacaagtgt gcttctagta atgcttctag cgccttctaa cattgaagaa
     1141 gcatgtacaa tcgacgtaaa accatatttt tgccgaatct tgtcaataat tttatctaaa
     1201 ttttcttcgt caatttgctt ttgtggatca ctaaataaat ccagctgaag cgaatcggtg
     1261 tacacaagct tgctataggt tattccaaca tgccttactt cttgtccttc ataatactta
     1321 tcaaacaaga aaagacaata attctgcaat tcctttgtat tatctgtgat agggatcttc
     1381 atctggtgtg aaaaccctgg tctcgtttct aagatcgacg tgccaatgtg taaatggaca
     1441 caacctgttt tacagttatg ctgcctaatg cgtatcgcta cttgttccgc catttctttt
     1501 accaccagct cgatttcatt tcttctagta taatctcgtg gtaacacttg tgaatttcca
     1561 tatgattttt cctttgtcgg ttctggtggg attgctatat ctgttcgatc gatcccatta
     1621 gcatggaagt acagctgtaa gccaatcaca cctagtctat tcttaatcgt ataaggattc
     1681 cagttagcaa gatctctaat gctcataatc cccatctgat tgagtctttt tttcattcga
     1741 gagccaattc cccaaaagtc cgtcatttca ggaatattcc atactttttc aggaacgttt
     1801 tcgtacgtcc attccgcaac aaatccttca ttatgctttg cttcgttgtc taaggctagt
     1861 ttagccaaaa ggggattatc tccgacacct actgtagcaa tcaatcctag ctcttcttta
     1921 atattctcct ggatcatttg agccagcttc tttctccgtt gacttcgtgt tccttcagtc
     1981 gtaaaaagat tcagtgatcg ggtcactttt aagattgatt catcgatcga gtaaatcagt
     2041 agatcttcat cagccacata tcttctgaaa atattattta cctgcatatt tcgcttgata
     2101 tataggttca tacgtggtgg aacaacgtgt agtgttttag gaaatggttg tggtaagtca
     2161 cgtggtctac tcacatttgt aataccatac cgcttttttg cttcaggaga agaagctaat
     2221 atcaatcctg aaccagtatt atcagctcga ctcataacaa caagttctgt tgttaatgga
     2281 tctaaatttc tttctataca ttcgacactt gcgtaaaagc ttttcatatc gattaaaaag
     2341 taatcattta ctggctcttt tgaataatcc atcataaata acactccatt ctttcacatt
     2401 atacaaacat atgttcgata ttgtaaagaa gaaatagcta aatacataaa aaaagaagca
     2461 taggtatgct atcaccctgc ttcttctttt gatttgtatg atcaatttat tctatcactt
     2521 tactaattaa tttgaaaatc taataaaaac tctcactcta aaagagtgag agactgcaaa
     2581 ttagagtacg gacttttttg gagttccgtt ctttaatatt aacaaatgaa taaaatcctt
     2641 acaacatttg agaataagtt atcagtagac acttacaaaa aattctcata ctatttcctc
     2701 catcattagt ttttgtctat ataaggttta ccctaaatag acactggtat aacattgaaa
     2761 aatatggctt cctcgtgtat gattagggtg tattttaaat agttgcagaa agtaggtaaa
     2821 agttttgaga gttgcataca tacgtgtctc atcgatcgat caaaatgaac aacgccagat
     2881 tgaagaaatg aaaaaattcg gtgcagagag aattttcatc gagaaacaat ctggcgcaac
     2941 gattactcat cgacctgttt tccaagaagc attagattac gtccgagatc aagatatttt
     3001 tattgtggaa gctattgatc gacttggaag aaattatgac gagatcatcg cttcagtcaa
     3061 ttacttgaag aagaaaaatg tgaagctgat cattactagt ttaccgatca tggctgaagc
     3121 aattggcaat cctctcctgg ataaattcat taaggatctg atcatccaaa ttttggccat
     3181 gatcgctgaa caagaacgga ctgaatcgaa acgtcgccag gcacaaggaa ttaagatcgc
     3241 aaaagcaaac ggcgtctaca aagggcggcc caaattatac agtgcagacg caaaagatcc
     3301 ccaacgtcgc cttgtttaca aaagcatcgt tgaagatctt aaaaatggtg ttgcgattgc
     3361 taagattgct aaagactaca atgttacgag acaaaccgtg tatagaataa aaaaagacag
     3421 catggtcaat gacaaatagt tgatcatgct gcttttatta tcttctcatc tttaatttcc
     3481 tacatataat tactatctat aaaattaagt cttactcaga acagataaag cataaaattc
     3541 caacaaacca ttttttactt aactaaataa agagtctgtt aatataatct tcacttattt
     3601 acgttaatcc cctactgtat ttgttggttc cttatctata ttttctacaa aatccttatt
     3661 atcttgtgat ttagcttcgt ataattcttt gtatgtcgac acattggtta tactaattcc
     3721 tatagctagt tcttgagact ctacttttct ctctagctcc tttgacaaag tgatttgaga
     3781 tttatttggt tccgttggag tcaattctat agattcttca taaaaatctc tatacataaa
     3841 gctatcatta attttataaa aaaaattaaa tgtttttagc actgccatat aacattcaaa
     3901 acattcttct atagttggtt tacttccttg aggagaatga accaatttat tacgtttttc
     3961 tatgaaattt ttaatttcct ttcttatttc tttcggaaac tcaatattaa agtacccttt
     4021 aaacatgctc cctaataatt tgtctacagg gggagattgt aaattctcaa atattagagt
     4081 taaatcaggt ttctcttgtt gataaaattc ctttacccct atttcacagg ctgtaattat
     4141 cgaaataaac ctatctctag tatttgatat atttttactt cttttaagga gtataagaga
     4201 aaaggggata ctttcgtgtc catgcatgta attaactaat tgttgagctt cagaagttat
     4261 atctctaatt atatagttaa cggaattagg aagtgtcttt aactctaatg aaatttctat
     4321 ccaattacta tcttctaatc tgtatatgct cgaagtataa tttgattcgt cagcaagcat
     4381 cgctacatcc caaacactga tcataaaatc ttttaaacgt tcaatcattt cagcaatatt
     4441 gctaaaatca gctaattttt ctttagaata aaaaaaaaca tttatatcag aatcaataaa
     4501 ttctattttt ttattactat atcgtcatca ttatcttgac catttatgtt tattgttccc
     4561 tgagtgggga gtacttcttt caaattcaag ttaaatttat attccattac ttctcctcca
     4621 atatataaaa attacttaac tgtatccaaa tttaatatgt aaataaatca ttaattttta
     4681 gctaaattct atgagaagtt tatttttgtt gtttttgcta attaactaaa actagtacaa
     4741 aaaatttaaa atagattatt aaacctattg cttattctat tcagtcatat atataagcgt
     4801 catcctttag taactaacat cccacactac aatagtatta taacatatct attcaacttc
     4861 aaattgttga aatttaagcc atttatattt acttttcctc aactttagaa atgattttac
     4921 taaccttata tccgtaatac gcgtaacaaa cacattcatt aataacaatc aacactaagc
     4981 tatattagct ttttaaatga ctagggtaaa taaaataagg atcaaaaact tttaagtttc
     5041 tgaccctttc cttacttccg attggttaat agtgatcttt tgcagaataa ataaatatcg
     5101 tttcattttc aactctatat atcagtctat gttcatctgt aattcttctg gaccattttc
     5161 cagataaatc atgctttaat ggctcaggtt ttcctaatcc agcaaagggg gaacgatcga
     5221 tatcttttat taacttgtta atctttttta tattgctttt gtttccttgc tcatgccaat
     5281 aaagataatc atcccaagca tcatcagacc aagccttaat catcagattc aacctcgatt
     5341 aagtcatgtg ttttaaatgc acctttggag aattgttcat ctcctcgacg aattttttcc
     5401 atgacgtaat tattagaaag tgttctcaac gtttcttgca tagaatcata atctcttttt
     5461 gataatacaa caactgtatc ttctacatct ttacttgtta caataagtgt ttcagcatcc
     5521 tcattaactt gtttcatata actacgtaaa ttttggcgga aatttgaata agctactgct
     5581 tccattcctt tcacccctta tttatttcta taaaacaatt gtacattata ttgtacaatt
     5641 aagcaaatga ttaatattct aacttcttat aattaaaagt gctatcactt ttagttttta
     5701 ggataaaaag tgacgtcact ttttgagtgc tggtacctca aatcctgctt tttcttgggc
     5761 aatcaataaa tctaacgcaa tacacataat cctggattca cttttgccgt acttctgctt
     5821 tagttgctgc aattcttttt gtctcttttc atccaacgta acgggtaacc gtttatttcc
     5881 tattgcaatt ggcattagta ctctctcctt tcatcgaaat aaccctatga aaaatatggc
     5941 tgcaatcatc ttgaatagta gactcacaag ggctaataca aagcgccaaa agatcaaaca
     6001 aaataccagt attgccaaaa atactacgaa gtttaaatgc acagctgcag catggcgcat
     6061 aagtatttcg ccaacaaata ggactaacaa tagaggaatg attttattca tatggatctc
     6121 cttctttctc ttaggttatc gggtgttgcc cgcttatttc gcaccaccta agcggcgggg
     6181 gcggttggag cgattggtgc gaaataagaa ccattccctt agttactagg ttttttgtcc
     6241 ttatttcaca cattctcact tttcggtata aatgattatt gccttttttt cctttcaaat
     6301 cgttgatatg gcattcgttt acggtcaagt tcattttgga tttcttctgt atcgtcgtaa
     6361 gtataggtgt ctaaaaaatc agttaaagtc gtgtaccagt cgtcgcctgg gttatctact
     6421 tcttctacat attccctcaa aaatgcttcg ggtacagcga gttcataatc cattcccatt
     6481 aacacgatag attccgttcc acacgtcaaa aatctagtaa atacaaggta ataatcgtct
     6541 atcgtcgcat ctttgctgtt tagctcttcc atttcttctt ccattaattc catgctctca
     6601 aaaattgaat aatattctga ttctgagtaa tagtgtttcc tgcaaatcgt gtagctgaca
     6661 aagttttcga ccagctcact cctttctagg taaacattca tgatatattt ttctgtttct
     6721 agtcgtagaa gctccgttcc tttttttacc gtttcaggac gacgtttata cacgtctaaa
     6781 cgattatggc tgactgtgac cttcgtttga ctcgtttcac tttccaaata caattgttct
//
LOCUS       DADQDV010000111         6680 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.114, whole genome shotgun sequence.
ACCESSION   DADQDV010000111 DADQDV010000000
VERSION     DADQDV010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6680)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6680)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6680
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.114"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(89..547)
                     /locus_tag="J8S10_002776"
     CDS             complement(89..547)
                     /locus_tag="J8S10_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HAZ9631334.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(560..1885)
                     /locus_tag="J8S10_002777"
     CDS             complement(560..1885)
                     /locus_tag="J8S10_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005227470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HAZ9631335.1"
                     /translation="MKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDEER
                     NMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKIPL
                     KHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVRRK
                     YPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREIMP
                     EIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVVEH
                     TDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLNDDR
                     RRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAVEK
                     LLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(1902..3314)
                     /locus_tag="J8S10_002778"
     CDS             complement(1902..3314)
                     /locus_tag="J8S10_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAZ9631336.1"
                     /translation="MNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADDMLNIPVIGAA
                     GNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMDPEVNMGIFGG
                     IISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLGFIWPLIQIGI
                     DNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSPSKEVFRGEMT
                     RFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMGSGAGTSFIAN
                     ITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVDYLINFRIATN
                     AILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEETELGLASKNYE
                     YMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISGIIKPTEKNYQ
                     IIIGLEVTYVMAEFNKLLEE"
     gene            complement(3331..4095)
                     /locus_tag="J8S10_002779"
     CDS             complement(3331..4095)
                     /locus_tag="J8S10_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HAZ9631337.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(4199..5074)
                     /locus_tag="J8S10_002780"
     CDS             complement(4199..5074)
                     /locus_tag="J8S10_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAZ9631338.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(5329..5413)
                     /locus_tag="J8S10_002781"
     tRNA            complement(5329..5413)
                     /locus_tag="J8S10_002781"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5377..5379),aa:Leu,seq:caa)
     gene            complement(5431..5502)
                     /locus_tag="J8S10_002782"
     tRNA            complement(5431..5502)
                     /locus_tag="J8S10_002782"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5468..5470),aa:Gln,seq:ttg)
     gene            complement(5512..5584)
                     /locus_tag="J8S10_002783"
     tRNA            complement(5512..5584)
                     /locus_tag="J8S10_002783"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5549..5551),aa:His,seq:gtg)
     gene            complement(5646..5730)
                     /locus_tag="J8S10_002784"
     tRNA            complement(5646..5730)
                     /locus_tag="J8S10_002784"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5694..5696),aa:Leu,seq:caa)
     gene            complement(5751..5821)
                     /locus_tag="J8S10_002785"
     tRNA            complement(5751..5821)
                     /locus_tag="J8S10_002785"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5787..5789),aa:Cys,seq:gca)
     gene            complement(5867..5938)
                     /locus_tag="J8S10_002786"
     tRNA            complement(5867..5938)
                     /locus_tag="J8S10_002786"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5904..5906),aa:Gln,seq:ttg)
     gene            complement(5950..6022)
                     /locus_tag="J8S10_002787"
     tRNA            complement(5950..6022)
                     /locus_tag="J8S10_002787"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5987..5989),aa:His,seq:gtg)
     gene            complement(6025..6098)
                     /locus_tag="J8S10_002788"
     tRNA            complement(6025..6098)
                     /locus_tag="J8S10_002788"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6064..6066),aa:Trp,seq:cca)
     gene            complement(6105..6185)
                     /locus_tag="J8S10_002789"
     tRNA            complement(6105..6185)
                     /locus_tag="J8S10_002789"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6149..6151),aa:Tyr,seq:gta)
     gene            complement(6187..6262)
                     /locus_tag="J8S10_002790"
     tRNA            complement(6187..6262)
                     /locus_tag="J8S10_002790"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6227..6229),aa:Phe,seq:gaa)
     gene            complement(6298..6370)
                     /locus_tag="J8S10_002791"
     tRNA            complement(6298..6370)
                     /locus_tag="J8S10_002791"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6335..6337),aa:Asp,seq:gtc)
     gene            complement(6380..6452)
                     /locus_tag="J8S10_002792"
     tRNA            complement(6380..6452)
                     /locus_tag="J8S10_002792"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6417..6419),aa:Val,seq:tac)
     gene            complement(6468..6539)
                     /locus_tag="J8S10_002793"
     tRNA            complement(6468..6539)
                     /locus_tag="J8S10_002793"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6504..6506),aa:Glu,seq:ttc)
     gene            complement(6554..6643)
                     /locus_tag="J8S10_002794"
     tRNA            complement(6554..6643)
                     /locus_tag="J8S10_002794"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6607..6609),aa:Ser,seq:gga)
BASE COUNT         2009 a         1473 c         1087 g         2111 t
ORIGIN      
        1 taaatctagt gattgaaaca tatcatttca aaaaaatttt gtaaattcac ccataaatat
       61 caccctattt aacttttttc atcgtacact aaaattcaaa acaactatct ttaatcttta
      121 cttcttggtt ttgttttaat aaatttcctt caaaaatgcc tggagaaact acaatgatca
      181 ccgtatcttt ttgtgcttgc tccaacttct tcaaatctat aatagctaac agtgtccctt
      241 cttttacctc ctggttactt tcaacccgta tctgaaacgg acttccttcg agttcaactg
      301 tatctaaacc catatggatc agtatttttc tgccagattc actttcgatc gttatggcat
      361 gtcgggtagg aaatatatta tcgattattc ctttaactgg cgcatggata tatccatcat
      421 gattcgttat agcgtatcca actcctatca tttttgaaga aaagacctcg tcttttactg
      481 ctgttaatgg aataatttga ccactagcta cagcttttag aatgtttctt gttttaaaga
      541 aatgcacttt ttatcacctc tactttaatg ctggccaata ttttttgttt actttgatca
      601 tttcatctag tatttttttt gcgactctgg catttggtac ggtttgattc aatgtaaatg
      661 cttgtaaagc tttttgataa gaaccttcaa agtaagcatc tactagtaac ttctctactg
      721 caacttgtgc ctccatcaat cctttatgaa aatcactgat tggttttctt agtgtaattg
      781 gctccacacc agttgcacca acatatgccg gtatttcaac aactgcatct gaccgtagat
      841 tcggaatcgc cccttgatta ggaacgatta gcataaagcg acgacgatca tcattcaaca
      901 aggaaatagc tatatcgacg atatattgtc catgctcccc aaaattaaag ttcaatactt
      961 cttccacaat accgcggcgt attttatcag ccatttcttt ggtatttttc tctcgtccat
     1021 ccatgaccat attagcacgt gtatactctt tgtcagtatg ctcaacgacc atatcaggat
     1081 ataagtaata ctctaagtaa ttattcggga tattacttgg aaaatttttc gtgatgactg
     1141 acatcatttg aaaggttttt tgccaagttt tatctcctat attaaaatcg gcgacttgca
     1201 tttcttttgt tattagtttt tcaataatct ctggcataat ttctcgttgc aattctttat
     1261 cataaatcga tgtataccag ccaaagtggt ttaaaccata atacgtaacg atccaattct
     1321 tacgatcata accgtaattc actgcaatcg tttcttcaat tgaaatagtc atatcacagg
     1381 cattaatcat ttttacattc ggatatttac gacgaacagc ttcagaaacg atcgactctg
     1441 gatttgtata attcaaaatc catgctttgg gggcatagtc ttgtatatga tcgacaattt
     1501 ccaataaacc tttgattgag cgcatcccat aagcaaatcc tccgagtcca cacgtttctt
     1561 gtcctactaa tccatgttta agtggaatct tttcgtcctt ttctcgcatc tccaatcctc
     1621 caacacgaat ttgtgagaaa acaaaatcgc atcctgtaaa agcaagcttt ggatcatccg
     1681 ttgcacgaat gcgaatattt gaaaaacctt ttcttttcag cataaattta acaatcaagt
     1741 acatatccat atttctttct tcatcaatat catataaacg tatttcagat aatggcaacc
     1801 gtttttcatt gttcaaaatg gcttgaacga ttcctggtgt atacgtactc ccgcctccag
     1861 ctatagtgat aatctgtttt ttcatcatca tcttttcctt tctattcttc taataattta
     1921 ttgaattctg ccataacata agtcacttct aagccgatga taatttgata atttttttca
     1981 gttggtttaa tgatcccgct tatccctaat tgcttgattc gctgttcctc gaccatggtg
     2041 ggatccacta cctctacccg taggcgtgta ttacaactat agacatccag gatattggct
     2101 tttcctccaa acgcttgtag catttttgtt gccatatatt cataattttt acttgctaac
     2161 cctaactctg tttcttctaa ggttacttca ttgccaaact ctgccttagc ttcacgtcct
     2221 aatgtctgaa tgtttctctt attgatcaaa taataaaaag taacgtaata caaggcaaaa
     2281 aagaaaattc cgattggaag aatcaaaata gcattggtag cgattcgaaa attgatgaga
     2341 taatcaacaa tacatgctcc gaatgtaaaa ccaattcgta tattgaataa gtaacagaca
     2401 atccctgcta aaccggcaaa aagtgcatgg atcacgtaca acataggaga aagaaacatg
     2461 aaactaaatt caacaggctc agtgatattt gcaataaatg aagttcctgc accgcttccc
     2521 atgattcctt tgaccatctc tttattttct ttataagctg ctttatagat agctagacat
     2581 atagctggta taccaaacat cattactaca aaaaaaactg ataaaaacag tccagcctga
     2641 ggatctccgt tgataaagcg tgtcatctct cctctgaaaa cttccttgct aggagatgta
     2701 tagcttccta aatcgtaata aatatacgta ttcaacacat ggtgcagtcc aaaggggatc
     2761 agcaaacgat tcaaaaacat aaatatcccc acacctaatg ctcccatatc aacgagcagt
     2821 tttgcaaaat tatcaatccc aatttggatg agcggccaga taaagcccaa aaaaacagct
     2881 gcgattgttt gtagaatcat caccatagtc aatgggaatt tttcgcccgc aaaataagaa
     2941 aaaactactg gtaatttttg ttctttaaag cgattatacg tccatgccgc tactaaaccg
     3001 gaaataattc caccaaaaat ccccatattc acttctgggt ccataatttc taagcctttt
     3061 ttcaaggtag caatcgctaa aaaaccagta agtgcaggta ttcctttgtc cttatttttg
     3121 acaaaaccga ttgcaactcc tatagcaaat aagatatcca agtttccaaa aacggcattt
     3181 ccagctgcac caattactgg gatgttcagc atatcgtcag ctgataaacg catgatcaat
     3241 cccgctaatg gcatcgctgc aactggaagt agcatcgctc ttccaagctt ctgcacattt
     3301 gatttaacat tcatttttat tcctcctcta ttaaatatcc tcatatgtta ctaactcaat
     3361 caaaggatca tttttcactt tttgagcaaa tgctgaatga attaaaaatt cgacttggtg
     3421 ggtacgagga tacacaaaac ttgaaccatt taacaattcc tgatccaaat acgctgcgtg
     3481 acacatgact tcgatcgttt tatcttctct caatatcatg agtaaacttg ccaaatattc
     3541 ttccacactc gtattgattt gtcgtttttt ttcatcagtt tctcctacga catcgaaaca
     3601 aggctcaaaa taatcgacat gacgaacttc atcttttcgt tcaaagttgc tccgaaccgg
     3661 caaatcatat ttttttgcta atgtaacaac tacctcctga ttttcatcca aagtatgagt
     3721 atgatgatga ctgtctaaat gagttggtat gatccccgca tgataaattt tttgaatctg
     3781 agcattccat tcctgataca gttgatcttt gtcaatgtta aatggatgct gataataaga
     3841 taaggatctg aactctccgc tttcgataag agtatcgaca gttttgagga gtggtttgcc
     3901 acacgtcaat gttaaatgga ctcctacacc tagcctaggc atttcctttc ttagtttcac
     3961 agcatgctcg aaacccggca tatttgccat caatgtagtt gatgtcaaaa ttcctcgctg
     4021 ataagcatcc ataatcccat aattcacacc atggctatag ccaaaatcat ccgaattaaa
     4081 aatcactttt cccatttcat tctccttctt ttttctacta aaataggcgc aaccaaataa
     4141 tcatagtcca tttactatgt gtcatttggt tgcgcctata gatagttacg cccttatttt
     4201 aatagattct tgctagatga attgccaaat agatgatttc attttcttga atggcaagtt
     4261 gaaattgctg ttcgatgata tctttaatct ttagtgctgt acaatacgct ttgctatgtt
     4321 taaatgtttc agtaaaaaaa ccaatatttt ctactggcgt ttcttcctga taaatcaagc
     4381 gtttaaccag gaatttgata tgaaccatta agcgatgata agtcagtgat tctttatcat
     4441 aaacgtttga ataggatttt tctagatggg acaaaatcgt ggtcgtcatt tctactattt
     4501 ttaagctctt taaactatta ggctctccta gctcagcatt aatgatatgc atagtgatga
     4561 atcctacttc atttgaccct aactcggttt gatatcgatg attgattcgc tcgaccactt
     4621 ctactgctat atcatattca tttggataaa ggaatctcat ttctggcaac ataattgctg
     4681 tgacatctct atcttctctt tttcgttgaa tagcaaaata aatatgatct gtcaatgtaa
     4741 tatagatatt tgaatctaat ggagaggaga tcctagctgt tatcagttca atcacttctt
     4801 ccgcaaaatc cataaattcg attggaatct gcgagactat ctcactgaat cgtttgatct
     4861 tttctttaga atctaataca aataatttgt cagcatcctc aacatcaaat ggcttactca
     4921 ctttagcaga aaagccaatc cctttcccca tcgcaatttt ttctattcca tcgtcatcga
     4981 tcaatacagc attatgattc agctttttca tcacatacac cgttaattca cctcctctat
     5041 atgataaaac aaaacaactt gcagactcct tcatacatat ttttgtctcc aaacaatttt
     5101 taaagacaaa aaacgaccta agaaagaacc ctttcttagg tcgtgcctaa ttgaatagta
     5161 gcaccctaca taatttacaa aaatagttta acacataata aaagcgttat caatatcttt
     5221 tttactcgtt ttatgataat acttgtatcg aattgatttg gaggtaatta cataaaaaca
     5281 aaaaaaatat agcaactctc tataagaaag ttgctatatt gataattata ccggcggccg
     5341 gggtcgaacc ggcacgtcct caacggacac tggattttga gtccagcgcg tctgccaatt
     5401 ccgccacgcc ggcaaattta aaaataataa ctggggtagc tggattcgaa ccaacgcatg
     5461 agggagtcaa agtcccttgc cttaccgctt ggctataccc caagaataaa gggcgaatga
     5521 tgggaatcga acccacgaat gccggagcca caatccggtg cgttaaccac ttcgccacat
     5581 tcgccatcat aaaagatgtt atttaatttc tcaataaaaa actaagatga agacatctta
     5641 gtcaataccg gcggccgggg tcgaaccggc acgccctcaa cgggcactgg attttgagtc
     5701 cagcgcgtct gccaattccg ccacgccggc aagttgattt attagtacta aggcggtaac
     5761 cggatttgaa ccggtgatga aggttttgca gacctctgcc ttaccacttg gctataccgc
     5821 cattatacta ttatcaatct ataaaataaa gaataaatta tagaaactgg ggtagctgga
     5881 ttcgaaccaa cgcatgaggg agtcaaagtc ccttgcctta ccgcttggct ataccccaag
     5941 aataaaaagg gcgaatgatg ggaatcgaac ccacgaatgc cggagccaca atccggtgcg
     6001 ttaaccactt cgccacattc gccatggcag gggcagcagg aattgaaccc acactaacgg
     6061 ttttggagac cgctgttcta cctttaaact atgcccctat aaaatggagg agagtggatt
     6121 cgaaccactg aaccctaagg aacggattta cagtccgtcg cgtttagcca cttcgctact
     6181 cctccatggt ggcgcgggac agaatcgaac tgccgacaca cggagcttca atccgttgct
     6241 ctaccaactg agctaccgcg ccatatttta aaattattaa ttgaataaca agaacgacgg
     6301 ttccgacggg aatcgaaccc gcgatctcct gcgtgacagg caggcatgtt aacccctaca
     6361 ccacggaacc agttcattat ggaggttaac gggatcgaac cgctgaccct ctgcttgtaa
     6421 ggcagatgct ctcccagctg agctaaacct ccaacattca attaaaatga cccgtacggg
     6481 attcgaaccc gtgttaccgc cgtgaaaggg cggtgtctta accgcttgac caacgggcca
     6541 ggtaaatttg ctacggagag taagggattc gaacccttga gacagtttgg caccatctac
     6601 atgatttcca atcatgctcc ttcggcctct cggacaactc tccagagtga aagaagctca
     6661 atactctttc tcaaaatgag
//
LOCUS       DADQDV010000112         6645 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.115, whole genome shotgun sequence.
ACCESSION   DADQDV010000112 DADQDV010000000
VERSION     DADQDV010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6645)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6645)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6645
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.115"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(98..1228)
                     /locus_tag="J8S10_002795"
     CDS             complement(98..1228)
                     /locus_tag="J8S10_002795"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HAZ9631339.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     gene            complement(1877..3079)
                     /locus_tag="J8S10_002796"
     CDS             complement(1877..3079)
                     /locus_tag="J8S10_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAZ9631340.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3139..3342)
                     /locus_tag="J8S10_002797"
     CDS             complement(3139..3342)
                     /locus_tag="J8S10_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAZ9631341.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3484..4716)
                     /locus_tag="J8S10_002798"
                     /pseudo
     CDS             complement(3484..4716)
                     /locus_tag="J8S10_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            4879..5691
                     /locus_tag="J8S10_002799"
     CDS             4879..5691
                     /locus_tag="J8S10_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAZ9631342.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
BASE COUNT         2020 a         1335 c         1035 g         2255 t
ORIGIN      
        1 aataaataat ataaaaggta aataaaaaag agtggatttc tccactccat gaaaagccga
       61 ctttttggga cgcttttttt tgccaagcct cacattttta tagccaaact tcttttgcga
      121 cttgctgcaa taattggatt ttcttccatt gttcttcttc tgttaaatgg tttccttctt
      181 ctgttgaagc aaacccacat tgaggactga tacttagatt ttccaatggt acaaattgtt
      241 gtgcttcttt tattcgttct tttattttct ccgtatcttc caaatctgga aacttagaag
      301 taactaatcc taaaacaact ttactttctt tgttactcca atgtcttaaa ggagtaaaat
      361 ctcctgctcg gtcagaatcg tattccaaaa agaaaccatc ataatttgtt gaaaacaact
      421 cttctgcaat gggttcatat ccaccggaaa acagccaaga agaagcgtga ttcccgcggc
      481 agatatgtgt tgtgatcgtc aaatcttctg gtttgtcttc cagtgcgtta ttgataatct
      541 ctgtacaaat atgggccatt tctttcggat caattccttt ttgaagaagt gcttctcttt
      601 tagtttgatc agctagaaac gcccaatttg tatcatcgaa ttgcaggtaa cggcaacctt
      661 tttcataaaa agcatgaatc gctgctttgt aagtagagga caagtcctca taaaaatcag
      721 atagatcagg ataaatctcc ttgatttttg aagaaccatc attagatagg atctcttgtc
      781 gtaaaatcat cgtgggacta gggatcgttg cttttgcaac aaaagtatca tctgtttcca
      841 ctacttcttt cagaaaagca aaatctttta aaaatgggtg atttggattg aaagataatt
      901 tatctactac ccgaatatta taagctggtg ctgcttttcc gtggaatgtt tgattatatc
      961 cagtttctgg aacatagcct tcgataccat ttagttcttc taaaaaatca agatgccaaa
     1021 atccacgccg aaattcacca tctgtaattc ctttgatgcc gactgctttt tggtcttcca
     1081 ctaatttttt tatttcctgg tcttcgattg cacgaagttc ttcttttgaa agtaagcctt
     1141 cttgaacttt ttttcttgct tctttgatcg attgcgggcg taagaaactt ccgacatgat
     1201 ctactgtaaa tggtctattt ttgctcattt cactcactct tttctttgtt ttttgtaaaa
     1261 aaaaatcctt ttactagcaa atactagtaa aaggacgatt atactcgtgg taccaccttt
     1321 tttcagaaaa aacattcttt ctctcagcct gacaataaaa tcagtggtct tggtaacgaa
     1381 agactgttcg tttttgccta cctttcgaca aaaaatcctc taaggccatt ttcgacagtc
     1441 aacttctagc tttttacacc aaccaaagcc tctcttgaac cattttctgt ctactttcct
     1501 tctcatcgga tactattaga ataaaattag aatagcatgt ttgaaagaaa agtcaatagg
     1561 gaataagaac aaacaaaaac taatttgtta ttcttagtaa tttgtttgtg gaatacaata
     1621 aagcttttct aatatgataa ttgttcagtc gtcctttcat cttagatcac ttccttaaaa
     1681 tgatcatacc cgtttcaacc acataaaaaa ggacttaatt ttgaaaaatt tcccatcaaa
     1741 actaagtcct ttttattata gttatgcaaa tttgcttatt ttctcgctat ttccgataca
     1801 tcttgaacag gagcaattcg actgaaaaca ctggtgcaaa agcatttatt tgtcttatgg
     1861 tagaaccgtg gaaaactcag actggtaata aattgtcatt ttttgaaaga atagcgccct
     1921 cttgaacatt atcaatcgca cttaccactt gttgatctga ctttgcatat aagtgaccgt
     1981 aagttcctaa agtgatttga atattcgcat ggcccaatcg ttcttgaata gatagcggtt
     2041 gaatattctg ctcaattaga aatgcaacat gagaatgtcg tagcgcgtga agcttaatcg
     2101 gtttgacacc cgctttttta gcagcttctt ttaaccagtt cgcaaaagaa taaggtggcg
     2161 taaatgttcc gtccaactga gcaacatatt caaaatttcc aatacgtttt tgcaagtcat
     2221 accactgtct gagttttaag gaaagcttct tccccaaccc aatcgttcga taagcacatt
     2281 tagttttggg agtcgaaaag taccaatcat cttttgtatt ataaatcaat gtcttctcaa
     2341 tcgttatcgt gtttttctca aaatctacat tcgaccaaga caaagcttca agttctccaa
     2401 tccgaatgcc agtataaaag agcatttcat acacaatctt ccgatggtgg gtttgaatct
     2461 tatcatcctt caattcattc atcacttttt gaaactcact gtgttcccaa aactcaactt
     2521 tcttattctc agaaggaagc gaagaaacat cttcaacggg atttttagca atcaccccct
     2581 ctttaacagc ccgatccaat acaattttta ggtgccctcg aatccgattg atataagatt
     2641 ttgataacgt ttcgccatta acttttttcc gtgaattacg tgactctgtc tggcttagtt
     2701 caaataacca atcctcaata tcgtgacttg taatatctcg aacacgaaaa tgatagaaaa
     2761 actgcatacg cttttcgaaa atgaattgcg cattctcata tgtttgactt ttgacctgtc
     2821 tctcgtacca ttttacaaac ctatccttgt aaaactcttc gaaagtcatt tgattggtag
     2881 aacacagttg attaggaatt gtcttgttaa aatcatgtgt ttccatgtac ttgtcataag
     2941 caattttggc atctttttgt gaagcataac ctcgtttagt cttctgaacc tttcttccat
     3001 tttcatctat acctagatac gctcggaaga accatttttt tgtcttttta tcttggtaaa
     3061 tatttttaat ttttggcatc gttccattcc tccctgtact tgagaaaagc tactttaata
     3121 gtaccgcgct tgtactgttt attccgcaac ttgaatgtga aaaagatgtt caattactcg
     3181 ggatggcacc acaccaactt ggcgattatt ataaaaatca ataccttcaa tccttgcaag
     3241 atatgccttg ctctctttaa tcattcgtgc agcttgacta ggtttaaagc ccatctctat
     3301 caaaattgca cgatttacca tgaaatcaca ttttgtttcc attctctcac ctcctgattc
     3361 tttactcctt ttaaaataat cctctttata atctattgtt tctcattcga tggttgtgtt
     3421 atactcgtct tgtcgaggcg gagtacgttg cacaacttgt tgtgtaagca gtactttgct
     3481 tttttagtag cttgttttct catttgatat actttgtaat tttcgttcat aatactcaac
     3541 ctcctcctga taatactccg ggtctgcctt catattttgg agaagtttga tctgtcttgg
     3601 attcatttct ccttgttcaa taatcaaagg caacaaggaa gaatgaaacg tttgatcgac
     3661 ctgtgcaata aaaactaatg atggtgaaac accatgaatt aaccaactca tagttttctc
     3721 aaaactttga ggaattgtat ctaaagaaat ggtgattgcg ccataattgc taataaaggc
     3781 tgcccatttg gcatcaactt ttgcacctag atcatttgga tcacggtcat aaaaacaaat
     3841 tgctccatta agtaactcaa agaacagttt ggttaaatca tgggtttttg aaataatctt
     3901 tgccaagctt tgcgctttct cttttcgata ccgtagttca aagcgattct ttacttttgc
     3961 ctcttctaaa ggaattcctc gtcgcttccg ttgttcatgg tccttctgat aaaagcaaaa
     4021 acgacactga ctcttctttg agcctaaata caaggtctca ccatttgatt cattgtttat
     4081 gatatccgta ccgccatgag attcactcac ttgaaaagtg gtccacacat ggcctagtat
     4141 taccttatgc ttaagttctg gaatgctgag actccccaca aaatcatcta aagtaaaatc
     4201 aatccgtgta aagttcccct gataatctaa taccttacga aaaaactgtt gccaatttgt
     4261 ttttcgtgtt tttagccatc ttgctaagtg tttacagcct tgacctgaaa actccatcac
     4321 agttccttta accgcatcgt caatggaata ccgaatcgtg attacttgat tccacacgta
     4381 ttggccaata tagccctttg gcgcataatc cagttcctca aaacgttcaa tgggcatttc
     4441 aataatctct tcaattagct ttaaatgttg attcgagaaa aagtgaatgg ttagataatc
     4501 aatcaaaaca cggttaactg gaacgacctc ttcttgcaaa ctatccaaca caagattcaa
     4561 tttttcttca cttaattgtc tcgttccttt ttctactttc gataataact atctcgaaat
     4621 ccccactttt tctgctaaat atcgttgtgt ccaccccctt tcttctcgag aaactcgaat
     4681 ggcttcaccg agatcatgtt gattaacttg gttcatcgac aaacctcctt ctgctattta
     4741 cttgtcaaag aacctattga acttatttta agtacatttt tattgtacgc ctgtatttat
     4801 tttaagtcaa tatgttttga ctttttttaa gtacacacgt atactaaatt taagaactta
     4861 tcctgaggag gagttttcat ggagatagac aagcaagcag tcggcaatcg aattcggcag
     4921 attcgccaag aattaaagtt gagtatggag aaatttggca aactaattgg tgatttaccg
     4981 cgaagtacag tcaataactg ggaacgtggg atcaaccttc caaaaaccga aacccttcac
     5041 caaatcgcag agataggtca tgtcaccaat gaatatcttt tgtatggtga tcaagagaat
     5101 caatacattt tagaaatgct ccaaaaaaag gcaggtaagc ttgatcctaa gattgaaggt
     5161 ctcatagtag acgaaatcaa acacgctgac cttgttagtg aaaaagaaat ggatcgaatg
     5221 attgaatttt ttattacaaa tctcattcca ccaactgaac aagaccagtt tactttccaa
     5281 tgtatcgatg aaaaaaagca gctttatctt ggttcaacta attttggtaa ggaagcccag
     5341 ctctatttgc aacatgataa tcaaaatcat attctgcaca tgatgccctt taccttctcc
     5401 aactttagtg tggatcgcat actcgtctat ttagcaaatc aaaaatccta ttcctatttt
     5461 gggaaacatt tacccaagga actaggtgag aaagccatcc ttctatactc aattaatcaa
     5521 ttgaccagcg atgtgcgaat tgccccgttg gtctattcag aagaaaccgc ttcttatcag
     5581 tacacagagg acaatcaata tctactagaa cagcaatatc tttatctacc attcgtgatg
     5641 gaagtcgaga aagaacgcct gttaaatgca gcgtatccat catcaaaatg aggtgacaaa
     5701 attgataagc acgtgacaaa gaaaatactg ctaggacact ccccaatggg tagttgtcac
     5761 agtttcctgt tctttgttag ccccctgtta gaaccggggg ctttattcct gcagtccggc
     5821 tacgccttcc tgcaatagac aaaactccag atcgggtaat tcgcttgtgg cgaaacccga
     5881 cctggagttt gtctctgtat tttgaaccct aaaaattaat caaacagact gatattctca
     5941 taatcagcgc gaaataagcc attaagtaca gttttcctac ctatttttga taacccgctg
     6001 gttagttaat attccttttc cgagagagat aaatgattgg ttaaatctat atacatctca
     6061 acctttaaaa atgttttcga aatacttcat cagtacatgt catacaaatt accagtgcat
     6121 tctcaaattc tagttcttta attgatttca gttgaggagc agttactttt ggcggaaatt
     6181 tccatttttg tccaaacctc ttcccccgat gaaatttctt tgttgcaatt attgcaatga
     6241 aaaatttttg tttcaaaaat atacataatt acttcctcca ataaaaacta tctacctctc
     6301 aaattatttt tctctaataa gaaaaacaga aaaggtaata agatacaaca gtgatgattc
     6361 ctaataaaga aaagactaca ataatatttt tctaacttat cgccttcaaa gaaatagttt
     6421 cttatttttc actaaaataa aaaatttatt gcaaaaaaaa tagaagtgac aaaattatca
     6481 atcatttcaa ggtaatataa ctacctgagt ttattatcga ttaaaatgct aactacattt
     6541 gcaagagaag cgagagttaa aggtaaatat agaatttcta cttttttagc aatagaaata
     6601 ggaataaaat atttaaaatg tatagaaact ttcttttttt ttctt
//
LOCUS       DADQDV010000113         6643 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.116, whole genome shotgun sequence.
ACCESSION   DADQDV010000113 DADQDV010000000
VERSION     DADQDV010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6643)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6643)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6643
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.116"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(1..859)
                     /locus_tag="J8S10_002800"
                     /pseudo
     CDS             complement(1..859)
                     /locus_tag="J8S10_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            1102..1557
                     /gene="tnpA"
                     /locus_tag="J8S10_002801"
     CDS             1102..1557
                     /gene="tnpA"
                     /locus_tag="J8S10_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HAZ9631343.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYQRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            1822..1920
                     /locus_tag="J8S10_002802"
                     /pseudo
     CDS             1822..1920
                     /locus_tag="J8S10_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(2143..2373)
                     /locus_tag="J8S10_002803"
     CDS             complement(2143..2373)
                     /locus_tag="J8S10_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HAZ9631344.1"
                     /translation="MDEAMDHPLLNKFIKDLILQIFSMIDEQEPTESKRHRAQGIIKI
                     AKRMFSIKGVLSYTVLIQKIPNHLVYKNNVED"
     gene            complement(2603..3421)
                     /locus_tag="J8S10_002804"
     CDS             complement(2603..3421)
                     /locus_tag="J8S10_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAZ9631345.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            3582..4271
                     /locus_tag="J8S10_002805"
     CDS             3582..4271
                     /locus_tag="J8S10_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HAZ9631346.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            4285..5787
                     /locus_tag="J8S10_002806"
     CDS             4285..5787
                     /locus_tag="J8S10_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010759843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAZ9631347.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            5800..6276
                     /locus_tag="J8S10_002807"
     CDS             5800..6276
                     /locus_tag="J8S10_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HAZ9631348.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
     gene            complement(6373..6483)
                     /locus_tag="J8S10_002808"
                     /pseudo
     CDS             complement(6373..6483)
                     /locus_tag="J8S10_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2172 a         1032 c         1204 g         2235 t
ORIGIN      
        1 acttgtcctc gataagaatt gtagcgccgt gatttacgtg tgtatgtcgt tacttttatt
       61 cctagcttct tgatcaggcg ctgaactttc tttttattga tagagaaacc gcggtttctt
      121 agttcattgg tcatccgtaa acagccataa tccttgtgct tctcccgaac tttaagcatt
      181 tccgcttcaa tctcttgatc tggattttta cggtccaatc gtttttgcca gtacataaag
      241 attgccttag ggaactttaa agtttctaga agctcaacta atttaaacgg tcctcggagg
      301 cttgcgatga ttcgtgcgat tgcttcattc gtcgttgttg ggcttcctgt tttcgcagct
      361 tcctcaattc ttttaaaaag gcattttcaa tttgaaggga acggactcgt ttctccaact
      421 cctcgatgcg ttcacgttct ttagacgttg ctttagttgt agattttttc ttatttttgg
      481 gttcattttt cttagacaag ataggtggac atcctttcgt ttttgagagt ccatcgatcc
      541 caccctcacg gaattgacgc atccaactag cgatcaaatt agggttgttc atgttaagtg
      601 tgttggcaac ttcacgatag gacagctcac ttgttagata taactctatc gcatccagct
      661 taaattgaac agaatatttt ttcttttgtc gctttcttac tagaccctct tcaccaaatt
      721 cttgataggc attgatccag cgcttcactt gtgatggagc cttaatggaa tatttctttg
      781 ccagataatc acttccgcct ttaccatcca agtaatcatg aacgatcttt aatttaagtt
      841 caaaagtata cttagccata aaaaataccg acctccaaaa gttagatttt ttggtctaac
      901 ttttgggggt cggtacaaaa cttaaaagtt ttagaccctt ttattttctt aatgacttca
      961 gtcagttttg tgcgtaaagc gtgcgaaaca agaaaaccgc gcgtttctac gcgtggaaga
     1021 agtatcttta gcgataaaaa ctcctttcga tatactagtg agtggctacc aaccgctcat
     1081 cagatcgaaa ggagtttttt catgtcaaat gacgataaaa gtttagcata tactcgttgg
     1141 aattgtaagt atcatattat ttttacacca aaatatcaac gaaaagtaat ctatgggcaa
     1201 ttacgaaaag atcttggaaa aatacttagg aagttgtgcg aaatgaaaga tgtggaaatc
     1261 atagaagcac atgcaatgct agatcatatt cacatgcttg ttcgagtacc accaaaaata
     1321 tgtatatcca gttttatggg gtatctgaaa ggtcgtagtg cggtactaat ccacgagcag
     1381 cacgcaaatc tcaaatataa atacggaaac aaatcctttt ggtcgaagag atactatgtg
     1441 agtacagtcg gattgaatca aaagacaaat gaaaaataca tccgtgaaca agaagctgat
     1501 gatcgcattc gatatattat aagtaaaaga gagtacgtag aaccatttaa aaaataaaga
     1561 gaagtaagtg agtgaagatg agcagttggc ggtcttttaa aaatcccctt ttaaggggca
     1621 gcgagtgtcg accccttcta gggggattaa aaatacaccc gtcctcacgg gtgtatgggt
     1681 tactgataga cttgatttta actggtgtca gaaacttatg tccagaaagg gtgatgaaat
     1741 tttggcaatt tacggctatt caagaattag cacaagcaac caagattaca aaacacaaat
     1801 tcaaacatta gaaaatgctg gcgcagaaat aatcttccta gaaaatcact ggattatcga
     1861 acacctttgg aagtattttt gagttacgta agtattgatg atctgtctaa cttaatttga
     1921 caattaagag tatatttact tcagatggta aggcaacaaa ataaaataca ataggcagat
     1981 gaactaataa ataaaatctg tattaaatac agataaatta atataaaaat caaaaggatc
     2041 ataaactttt aacaagtgat gaaatgggtg gaaattgatt cttatagaca gtttgtctca
     2101 taacattgaa gtattttgca attttagcat tgaaacactt ttttaatctt caacgttgtt
     2161 cttataaaca agatgattgg gaatcttttg aattaacact gtatagctta gaacaccctt
     2221 tatagaaaac attcgcttag caatcttaat aattccttgt gcccgatgtc gtttagattc
     2281 agtaggttcc tgctcatcga tcatggaaaa aatttgaagg atcagatcct taataaattt
     2341 atttaagaga ggatgatcca ttgcttcatc catactcgat aaactagtga taatgagcta
     2401 cacgtttttc tttcaagttg atcaatagct tccacgataa aaatatcttt agataaaatc
     2461 aagaaccgta ggaactacag ggatatttgg tcaataagag ccaccgctat tagtaaaaaa
     2521 taagctatca agtatgctct catcccaaga attgcctact tcaatcgtta aaaaccgtta
     2581 ggtttagcta agtgggggta gttcactcaa tacttttatc aataatagag cgcaaaactt
     2641 tttctcttaa ttcaactgaa tcaatattat tgttttgttc ataaccatga actaatagat
     2701 cacaaatata aagttgtgat atttttccag ctaaagatcc accattaaga aattcttcaa
     2761 tggctgtttg taaaactaag tctgcagact ttcctatagg tgaatgaata tagttagtta
     2821 tagcaataat ttttgcgcca ttttttttag ctattttcaa tgaatcataa gtatctttcg
     2881 ttttcccaga taaagaaaaa atgattacta aatcattaac tgttaataaa gaagcgactt
     2941 gggcttgaaa atgagggtct agtacagctt ttgcttgaac tcctacgcga agaaacatat
     3001 tttctaaatc aagactagta tttccactag atcccactcc aaatatatat atgttttttg
     3061 attgagtgat cattttaatg gcttcattca atttttcttc gtctaaaagc ctaatagtgg
     3121 aatagagagc ttctgttaaa ctattagcaa tttcatcata gtactttaca ctagtcggat
     3181 gttctttttt ttgactaaag tcttcctttg caatttcaat ttttaaatca gaaaaaccag
     3241 aaaaaccaat tttttgacaa aagcgaataa tagtagcatc gccaactttt gtgtttttct
     3301 taatatcact catcgtacta taaataatag ttttcccaga atttaaaata aaatcagcga
     3361 cttttttttc agacttcgtt aaaaatggat aattttcttt aattaaatag atataactca
     3421 tacaaactcc tctacaattt caacttttct ccattatact ccaaaataat aaaaaaaact
     3481 cctaaatact ccatttttat ctttactttt atgaaagcgg atgctatatt gtttttggag
     3541 ttgttatcca aaaataataa aaaattggag tgtttaggat aatggataaa aagaggtttt
     3601 tagatcttat ttcaaaaggt ttgattgttt cctgtcaagc attacctggt gaaccatttt
     3661 acaaagagga agaaagttta atgccttatt ttgctttggc tgctcaaagg gctggagcag
     3721 ttggtatacg tgcaaattct gttcgagata ttattgaaat tagaaagtgt gtatcattac
     3781 caatgattgg aattattaaa agagattatc caccagaatc tccattcatt actgccacta
     3841 tgagagaagt agatgaatta gtagaaaccg gtgttgaggt aatcgctctt gattgcactc
     3901 ttagaaatcg acatgatgga ctatctataa attcttttat tactaaaata aaagaaaaat
     3961 atcctcatca gttatttatg gcagatattt ctacatttga agaaggcaaa aatgcatata
     4021 aagcaggaat agattttgta ggaactactt taagtggata tactgaggaa agtaaaaaac
     4081 aagatgggcc agatatagat ttgattaaaa aattggtaga agaagggatt tgtgtaattg
     4141 ctgagggaag gattcatact ccagaacaag caaaagagat aaaaaaaata ggagttgcag
     4201 gtattgttgt gggtggtgct attactcgac cacaggaaat tgcatcaaga tttgttaaag
     4261 cattaagtta gggggagaaa taaaatgttt aaaaaatttt cacaattagg acgcgctttc
     4321 atgttaccaa ttgctatatt accagtagcc ggattactat tgggactggg aggagcgtta
     4381 acaaatgaga gtgctataaa tgcttatcca tttttagatc aaccgtggtt gcatacaatt
     4441 ttaagtatta tgagttatgc tggaaatgca gtttttgcaa acctagcact aatttttgca
     4501 attggtattg ctgtaggact tgcaaatgga gataaaggaa cagctggttt agctggtgga
     4561 gtagcttatc tagtatatac tgcaactatt agtgggtttc ttgaactttt ttcagcaaaa
     4621 gatgcaacac tagatacagg tgtagtggga tcaattgttg ttggtggtac tgttgcattt
     4681 ttacacaatc gttatagaaa aattgaatta ccacaattct taggtttttt tggaggatca
     4741 agatttattc cgattgtttc tagtttagct gcaatcatta ttggttcttt cttttattta
     4801 atttggccac caattcaaaa tggtttagta gttgctggtg aacaaattgc ccaaatgggt
     4861 agtttaggaa cttttttata tggtttttta ttgcgtttaa caggtgctgt tggactacac
     4921 cacaccattt accctttgtt ctggtataca tctttaggtg gtaccgaaac tgtagctgga
     4981 tcaacaattg ctggagccca aaatattttc tttgcccaac tagctgatcc aaaccacact
     5041 ggtctgttta cttatggtac tagatttttt gcaggaagat ttgcaacaat gatgtttgga
     5101 ttaccagcag catgttatgc aatgtatcgt gcaattccta agaaaaatcg taaaaagaat
     5161 ggtgggcttt attttagcgg ggcccttaca tcatttttaa ctggaattac tgaaccagtt
     5221 gaatatatgt ttttatttgt tgctccttgg ctttatgtga ttcatgcatt cttagatgga
     5281 ttatcttttt attttgctga tatcttaaat attcgtgtag ggaattcctt ttcaggtggt
     5341 ttgatcgact ttttattatt cggtgtactt caagggaatg acaaaactaa ttggttaaaa
     5401 ttaattcctt ttggtattgc atgggcattt atatatttct ttgtttttac attctttatc
     5461 aaaaaattta aggtagctat tcctggaatg gaagaagaat cagaagttca ttctgaaaaa
     5521 gtaataaaca aaaatacatc attacatgaa gagtctctta tcattattga agctcttggt
     5581 ggaaaagaaa atattgagtc tgttgaagct tgtgcaactc gtttgcgtgt tgctgttacg
     5641 aatggggaga ttattcaaaa acaaacaata aaagacactg gtgcaactgc tgtcttcgaa
     5701 gtgaagggtg gcatccaagc tgtttttgga gggaaagctg acttattaag tcaagaaatc
     5761 aatcaaatat taggaaaaga taattaggag gtttttaata tgtttgaaat tttcaaaaag
     5821 aaaaaacaag aaacttttta tgcaccttgt tccggaaaaa tcatttccat cacagaagta
     5881 aatgatcctg tcttttcaca aaaattacta ggtgatggtt ttgccgtcat acctgatggt
     5941 tcaaaaattt atgctccatt ggctggtcga gtaacaaata tatttcctac taaacatgct
     6001 attaatataa aaagcaactc aggcattgat tatttgattc atattggaat tgatacagtt
     6061 gaattacaag gagagccttt ttcgatttgt gttcaagaaa atgatgaggt tactcctgaa
     6121 acctcgttgg ttgatgtgga ttttgacaaa ataataaaat ctggtaaaga tacttctgtt
     6181 atagttgttt ttccggagaa aaatcagttc aatgatttaa taatagataa tggtcgaatt
     6241 gctcatggga attcatgtgg aaaaatcact ttttaaaaaa gtgtatataa aaagctataa
     6301 aataagctaa ataggatatt tgtcaaatga agttggtgaa cagaaagaac tgttttcttt
     6361 ctgttcattt ttttatttta ttagtaatga ttccccatgc caaatcatga tccgtaattt
     6421 aaagttataa aagcttcgaa atccattggc atttcgttgg aataccttga tatgattatt
     6481 caaatataaa atatagagag aagagagaga gggaagatat ttataaaggg caaagttatg
     6541 tttactcaac ttaggaaata gaaatagatc aatttatatt ctcttgtcaa tcgaatatga
     6601 accttagcac tatataccaa atatagtaaa atgctgaaag atg
//
LOCUS       DADQDV010000114         6516 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.118, whole genome shotgun sequence.
ACCESSION   DADQDV010000114 DADQDV010000000
VERSION     DADQDV010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6516)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6516)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6516
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.118"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(53..826)
                     /locus_tag="J8S10_002809"
                     /pseudo
     CDS             complement(53..826)
                     /locus_tag="J8S10_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            847..2049
                     /locus_tag="J8S10_002810"
     CDS             847..2049
                     /locus_tag="J8S10_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit R"
                     /protein_id="HAZ9631349.1"
                     /translation="MCTKLLQNTAHKNPYKTVDEATQLDLVIVVNQLLTGYDSKWVNT
                     LYLDKSLEYQNIIQAFSRTNRLNGPEKPFGTIRYYRKAHTMEQNIEEAIELYSGKQAK
                     GLFVEKLYNNLEKLNDIFEEIKSVFNISGIENFSHLPEVPGEIKQFVNLYNQLIHCYE
                     SAMIQGFTWAKSTYEIQDYEPITVVITEYEFNILAQRYSEIEREPRDGNDSIAYDIDY
                     QLPEGSRSRINYEYLNTNFKKYMNIKEERDSNLIQSLLNDLHRTFAQLPVELQPYAEM
                     ILNDVNNGELVIKEGWEFTDYLNEYQLSEEDDFIQDLVDSTNINEALLREMLDLRLTE
                     VNINEYSRFDKLKSSVNVGHFSGYIEKNLGKMVIPIKVNMLIDRLLRAFLLEDVFDVT
                     EYIKNYFN"
     gene            2782..3750
                     /locus_tag="J8S10_002811"
     CDS             2782..3750
                     /locus_tag="J8S10_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAZ9631350.1"
                     /translation="MDVAKTVNAIVEKNDGEISGIYLVACGGSLVDMYVSDYFLKAEA
                     SKCITGLYTANEFNHVTPKQLDDKSVVILCSHGGNTAETVKAGEVAQARGAVTVGLTH
                     NKTADLLKVSDHSFLYEWGDDAKIVNNPMAIILDLTVSLVNVTETFEHYGKFREGMKV
                     IDTVIENGIKQVQDRIKVFADKYKDETMFYILGSGPSYGHAYGFSICSLMEMQWLDST
                     SVHSGEFFHGPFEVTDKDTNFILLMSIGRTRALDERAKRFLDKYAERVEIVDAKELGL
                     DMISDEVSEFFNPILFYSILSEYRSALADARNHDLDVRRYMGKVEY"
     gene            3761..4576
                     /locus_tag="J8S10_002812"
     CDS             3761..4576
                     /locus_tag="J8S10_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 6-kinase"
                     /protein_id="HAZ9631351.1"
                     /translation="MKVLGLGDNVVDKYENLGIMYPGGNSLNFAVFAKKLGHESSFMG
                     VFGSDEEAAHVLSAIKKIGLDNSHSRFEKGENGCARVKIDEGDRIFLGSNSGGVTREY
                     PIQLTEEDREYLNQFELIHMGLYSHVNHLLEELQNVSGKISYDFSDDFTEEEVQRAID
                     KVDFGFFSIEDFSDEEVKQFLMKHFCERNDVLIATRGEKTAIGYDGAKFYEVNPVLEE
                     PVDTMAAGDSFLTAFLLYFLEGDDIVTAMKKGNEFAGKSCLVDGSFGFGIHYD"
     gene            4644..5354
                     /locus_tag="J8S10_002813"
     CDS             4644..5354
                     /locus_tag="J8S10_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAZ9631352.1"
                     /translation="MLDTNAQLPLYLQLKEILKNKINTGEYPENTKIPAESELIESYE
                     VSRITVRKAVEELVEEGYLLKKQGKGTFVNRHKVFRKIEYVMGFSESCKSNGFTPTSI
                     VLERKIIPATEGMAKKLDIAQGDDVLYIQRKRMADNIPIMLENNYFSYERYSFLMEEE
                     LTDSLYEVLKVQGTLAINPGETALEIVTADDQIAKIMEVAVGTPFFFMDTLINDQNNI
                     PIHVGNQYYLGEVYRFYL"
     gene            5390..>6516
                     /locus_tag="J8S10_002814"
     CDS             5390..>6516
                     /locus_tag="J8S10_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HAZ9631353.1"
                     /translation="MKQVLRSKMIFDGEQPPFKGYIVINEGIIEKVENNWNYSDLLNE
                     NTELIAYDDQFVMPAIHDNHVFFSGYLAMNAGIDLSDTSSANEAVERIKAVMNHKKAD
                     EPIYAHGWDAALWKTDPSEELLNEINHFGPITAIDKNRSHCWMNAIAKQTYGFTEKET
                     SAESRVLLIKEMLANKKLLAEVYAEFEALLLSKGVISMKEIVFDDAEFLSNIPQRKIL
                     SNLYVQAVQEPLQHELLYEYKEKVFPEKVRFGGVKIMVDGVVADRSGDIYGVYQSGVA
                     SPEIDYEAIKAEVAAFNEVEIPCCLTTEGDKAGYKAASILVEFGKRLPEGVFNSISDL
                     EMVTQKTAEKMNEGQVVAEVYPQILGLNQTLEEAYMSTVIK"
BASE COUNT         2196 a         1001 c         1329 g         1990 t
ORIGIN      
        1 gccaataaaa cttagtccga tatgcggcgc gttctgtgcg ccgcatattt ttttagtttt
       61 caaagatcag accttgttgt aaatagatcc gtgcccgaaa gttataaaag ttgcgataac
      121 caaacgcaat tcgtttaatc agcttgatct tgttatacag cccctcagtg acgccgtttg
      181 agtgggacac cttaaaggca tttgaaatac ccgattggta gcgatggaag atcgtgaatt
      241 tctttttaaa cgactgaggt aacgtagatg aaattgtttt aagggtttct tgaaagccta
      301 ccgtatctcg tttaacgaaa taatagcgta ataattgaca aaaatgatac gcagttcgca
      361 attcttcgtt gtagcttaac agctcattaa cgatttctgt ttgactaatt ggtcgtttaa
      421 acagtcgatg ataatgccgt ttgagtgcct cccatgtcgt ggaatctttg agtaagagtt
      481 tccaatatcg cttgagccga cggtacttct tctgattttc agagtgtgag gttcgaaaac
      541 gattcatgat ctggacacgt aattgattga agctgcgatt gatgtgttgg acaatatgaa
      601 agcggtcagt tacgatctcc gcatttggaa agaccgtttt aagcaactga caatagctgg
      661 cattcatgtc catcactagg tacttgacct ttaaacgggc ctttctagga aagcgcagga
      721 agtattgagt tagtttgtaa agtctgcgat cttcaagggt cgtaaatagc tgattggttg
      781 tcccatcaac acaaataaaa ctcatggaac cagaagtggc aacattgtgt acttttcttt
      841 gcaatcttgt gtacaaaact attgcaaaac acagcgcata agaatcctta caaaacagta
      901 gatgaagcaa cccaattaga tcttgttata gttgttaatc agctcttaac gggttacgat
      961 tcaaaatggg tcaacaccct atacttagat aagtcacttg aatatcagaa cataattcag
     1021 gctttttcac gcacaaatcg tcttaatggt cctgaaaaac cgttcggaac cattcgttat
     1081 tatcgtaaag cacatacgat ggaacagaac attgaagagg ctattgagtt atactcaggc
     1141 aaacaagcaa aagggttatt tgttgaaaaa ttatataata acttagaaaa gttgaacgat
     1201 atattcgaag aaattaagtc cgtatttaat atttctggca tagaaaactt cagtcattta
     1261 ccggaggttc caggggaaat taagcaattt gtaaatcttt ataatcaact aatccattgt
     1321 tatgaatcag cgatgataca gggattcaca tgggcaaaat cgacttatga aatccaggat
     1381 tatgaaccta taacagtagt aatcacagaa tatgaattta atatcttggc acaacgttac
     1441 agcgagatag agagagaacc tagagacgga aatgatagta tagcgtatga cattgattac
     1501 caattacctg aaggtagtcg tagtcgtatt aattatgagt atttaaacac aaacttcaaa
     1561 aaatacatga atataaaaga agaacgtgat tcgaatttaa ttcaatcatt gttaaacgac
     1621 ttacatcgca catttgcgca attaccagtg gagttacagc catatgctga gatgattcta
     1681 aatgatgtaa ataatgggga attagttatc aaagaaggat gggaatttac tgattacctc
     1741 aatgaatatc agcttagtga agaggacgat tttatccaag atttagtgga ttcaaccaat
     1801 attaatgagg cattattacg tgagatgttg gatttacgct taaccgaggt aaacattaat
     1861 gaatatagtc gatttgataa attaaaatca agtgttaacg taggtcattt cagtggatat
     1921 atcgagaaaa atttaggtaa aatggtaata ccaatcaagg taaatatgct aattgacaga
     1981 ttattgcgtg catttttatt agaagatgta ttcgatgtta cagagtacat aaagaattac
     2041 tttaactaga gtacacctac atcttatagt acataaaaaa attcatcttt tttagtttaa
     2101 taattcacca aaaaggtgag taatgccatt tttgaaaatt gagcttgttt tatgtctaca
     2161 tctgtatccg tatataatcc aaaggattat aaactcagaa gagtctttat tttttctgaa
     2221 tataactact gtatcaaaaa caatcgatta tgagacaaaa caaaatgacc tcttttattt
     2281 aagaaaggag gtcatttttt gtatcataaa ttgtattaaa atcaatgtat cactttttaa
     2341 tcaattttaa gaccataaat tgcgtactaa aagaaattct gcaattcaaa ataaagcatt
     2401 ttaagccatt ttcaaattta agtgcaccca tctacccgtc aaatcacttt attttccact
     2461 ccagtagttt cctaattcaa ctgtgtgcaa aacgatttct tctaaacaaa tcaagacaaa
     2521 cttataaacc ttcatcccag caccataatt atttaaatca taggcatttt tcgaaattag
     2581 tatatgtact caagtttcac tgcagattat ttatattttt tagagaaata aatttttcct
     2641 attgacaaac acaaagaaag cggatacaat acaattatgt cacatgacgt tatatgacgt
     2701 tatgtaatat ctttacattt aatcagttac ttttattttg gataaaatta acatttttaa
     2761 aattttaagg aggaaatgtt gatggatgta gcaaaaacgg ttaacgcaat tgtagaaaaa
     2821 aatgatggag agatttctgg aatttatttg gtggcttgtg gcggttcgct ggtagatatg
     2881 tatgtctcag attattttct taaagccgaa gcatcgaagt gtattacagg cttatataca
     2941 gcgaacgaat ttaaccatgt aaccccaaag caattagatg ataaatctgt tgtcattcta
     3001 tgttctcatg gaggaaatac agcagaaacg gtaaaagcag gagaagtcgc tcaagctaga
     3061 ggagctgtga ctgttggtct gactcataat aaaactgcgg atttattaaa ggtttctgat
     3121 catagtttcc tttacgaatg gggagatgat gcaaaaatag tcaataatcc tatggccatc
     3181 attcttgatt taactgtatc tttggtcaat gttaccgaaa catttgaaca ttacggtaaa
     3241 ttcagagaag gcatgaaggt tatcgatacc gtaattgaaa atggcattaa gcaggtgcag
     3301 gatcgtatta aagtgtttgc tgataagtac aaagatgaaa caatgtttta tatcttaggt
     3361 agtggaccat catatggaca tgcttatggt ttttcaattt gctctttgat ggaaatgcaa
     3421 tggcttgatt caacttctgt tcattctgga gaattcttcc atggaccttt tgaagtaaca
     3481 gacaaagata cgaattttat tctcttgatg agcattggac gcactcgtgc tttagatgaa
     3541 cgggcaaaac gattccttga taaatatgca gaaagagtag aaatcgttga tgcaaaggaa
     3601 ctaggattgg atatgatatc agatgaagtt tctgaattct tcaatcccat tttattctac
     3661 agtattcttt cagaatatcg ttcagcttta gcagatgcac gcaatcatga tttagatgtt
     3721 cgtcgctata tggggaaagt ggagtactag gaggattaaa atgaaggtat taggcttagg
     3781 tgataacgtc gtcgataaat atgaaaatct gggaattatg tatcctggag gaaattcatt
     3841 gaattttgca gtttttgcaa aaaaactggg acatgaaagt agctttatgg gagtttttgg
     3901 ctcagatgag gaggcagctc atgttttatc agcaataaaa aaaataggac tggacaacag
     3961 tcactctcgc tttgaaaaag gcgagaatgg ctgtgccaga gtgaagattg atgagggcga
     4021 ccggattttc cttggcagca attcgggagg tgttactcgt gaatacccga ttcagcttac
     4081 tgaagaagac agagaatatt taaaccagtt tgaattgatt catatgggat tatatagcca
     4141 tgtcaatcat ctattagaag agttacaaaa tgtttctgga aagatttctt atgatttttc
     4201 tgacgacttt acggaagaag aggttcagcg ggcaattgat aaagttgatt ttggcttctt
     4261 ttctatagaa gacttttccg atgaagaagt aaagcagttt ttgatgaagc atttttgtga
     4321 gcgaaatgat gtattgattg caacccgagg agaaaaaacg gctattggtt atgatggagc
     4381 aaagttttat gaagtgaacc ccgtgctaga agaaccagtt gatacaatgg cagcgggaga
     4441 ttctttctta acagctttcc tactttattt tctcgaaggg gacgatatag tcaccgcgat
     4501 gaaaaagggg aatgaatttg ctgggaagtc ttgtctggtt gacggttcgt tcggctttgg
     4561 tattcattac gattgagctt gttttaaatt cctgcatttg ataacctaaa gaaagaaatc
     4621 ccggtaaagt ggaggttaaa aaaatgctgg atacaaatgc acaattacca ttgtacttac
     4681 aattaaaaga aatattaaaa aataaaatca atacagggga gtatcccgag aatacgaaaa
     4741 ttcccgctga atcagagctg atagaaagtt atgaggtcag ccgaatcaca gtgagaaaag
     4801 cagtagaaga actggtagaa gaagggtacc tacttaaaaa acaagggaaa ggaacttttg
     4861 tcaaccggca taaagttttt cgtaaaattg aatatgttat gggtttcagt gagagttgta
     4921 aatctaatgg ttttacaccg actagcattg ttttggaacg caagatcatt ccagcaactg
     4981 aagggatggc aaaaaaactc gatatcgctc aaggtgatga tgttttatat atccagagaa
     5041 agcgaatggc ggataacatc cccattatgt tagaaaacaa ttatttttct tatgaaagat
     5101 atagtttctt aatggaggaa gagctgactg attctttgta tgaagtactt aaagtccaag
     5161 gtaccttagc catcaatcct ggggaaactg cacttgaaat tgtcacagct gatgaccaaa
     5221 ttgccaaaat aatggaagta gctgttggga cgcccttttt ctttatggat actttaatca
     5281 acgatcaaaa caacatacca attcatgtag gtaatcaata ttacctggga gaagtatatc
     5341 gtttttactt atgatttcct gttttgattt caaggagtag attttattta tgaagcaagt
     5401 attgcggtca aaaatgattt ttgatggaga gcagccacct ttcaaaggtt atattgtaat
     5461 caatgaaggg atcattgaaa aggtggaaaa caactggaat tacagtgatc tattaaatga
     5521 aaacacggaa ttaattgctt atgatgatca attcgttatg ccagcaattc atgataatca
     5581 tgtatttttc agtggttatt tggctatgaa tgctggcata gatttaagcg atacatcttc
     5641 agctaacgag gctgtagagc gtattaaagc tgtaatgaac cataaaaaag cagatgaacc
     5701 aatttatgct catggctggg atgctgccct gtggaaaact gacccatcag aagagctatt
     5761 gaatgaaata aaccactttg gtccaatcac agcgatcgac aaaaatcgca gccattgttg
     5821 gatgaatgct attgctaagc agacttatgg ttttacagaa aaagaaacca gtgctgaaag
     5881 tcgagtatta ttaattaagg aaatgctagc aaacaaaaag cttttagcag aggtttacgc
     5941 tgaatttgaa gcattactgc tttcaaaagg tgttatatca atgaaagaaa tcgtttttga
     6001 tgacgcagaa tttctttcta atatacctca gaggaaaata cttagtaacc tatatgtgca
     6061 ggcagtccaa gaacctctac agcatgaact tctatatgag tataaggaaa aagttttccc
     6121 tgaaaaggtc cgctttggtg gagtgaagat catggtagat ggtgttgttg cggatagaag
     6181 tggagatatt tacggtgttt atcagtcagg agtagcttca cccgagattg actatgaggc
     6241 aattaaagca gaagttgctg cattcaatga agtagagatt ccttgctgtt tgacaacgga
     6301 aggagataaa gcgggttata aagctgcgtc aattcttgtc gaatttggaa agcggttacc
     6361 tgaaggcgtt tttaattcga ttagtgattt ggaaatggtt actcaaaaga cagcagaaaa
     6421 aatgaacgaa ggacaagtag tagcagaggt atatccacaa attctcggct tgaatcaaac
     6481 gttagaagag gcttacatgt caactgttat aaaaaa
//
LOCUS       DADQDV010000115         6387 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.119, whole genome shotgun sequence.
ACCESSION   DADQDV010000115 DADQDV010000000
VERSION     DADQDV010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6387
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.119"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            330..1175
                     /locus_tag="J8S10_002815"
     CDS             330..1175
                     /locus_tag="J8S10_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAZ9631354.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1456..2676
                     /locus_tag="J8S10_002816"
     CDS             1456..2676
                     /locus_tag="J8S10_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HAZ9631355.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2673..5393
                     /locus_tag="J8S10_002817"
     CDS             2673..5393
                     /locus_tag="J8S10_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAZ9631356.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5377..6321
                     /locus_tag="J8S10_002818"
     CDS             5377..6321
                     /locus_tag="J8S10_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAZ9631357.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
BASE COUNT         2379 a          987 c         1231 g         1790 t
ORIGIN      
        1 aaggcaaaaa gatgaactag aaatagttca tctttttttg tttaaatctt ttgctaagtt
       61 gaactaatag agtcttttat gaatatcgaa gttagttttt cacctaactt cgttttttat
      121 agttggttat tataaaatag taatatagct gatttggatt caattcatat ttatttataa
      181 atcaaaaata cagagaatag tatataaatg tcctttccta ttcttaaaat gatgtttgta
      241 cttacttaaa ttaggtataa ttagtatatg ttttgtgaga aatttagact tacaataagc
      301 agtgaattta taatcaacgt ataggagaca tggatgaaat gaaactaatt ggtatagatt
      361 tagacggtac tcttttgaat tctgaccaga gcattagtca aaaaaatgca agaacaatga
      421 aacatttacc ggaagactgt tttccattca tttgttctgg aagagaagta gaagacatta
      481 ataatattct caaaaaatct ggtttaagga taccagcagt agggttaaat ggttctgttg
      541 gatttgatgg agaaaaaaag atatttgagt cttccttcga taaaaatgat gtaaaaaaaa
      601 ttgattctgt cctatcgaaa tttccaacca aaatatatac aaatctcgga agttatgaat
      661 ctcagaatta taaaaataaa atgaaaaaaa tttttcacga ggtagggagt gaattttcta
      721 tcaaagagct aaactatgag cttgagtatg aaaaatctat ttgttcaatc ccttataata
      781 atattgagga aattatagaa aaggatgcta tcagcattta caaatttttt atttttattc
      841 ctaatcgtca attgaaagct aatatattta accatttgaa aaagatgcta aatgtgtctg
      901 ttactgaatc ggcacctgta aatattgaaa tcgtacctca aaatgtatct aaaggtgtgg
      961 tgtttgatcg tttggaatca atctacaatt taaagaaacc tttgagaatc gcgatcggag
     1021 atagtttaaa tgacttatct atgtttgaaa gtgcagatat tagttttgca atgggaaata
     1081 gtcatcaaga aatcatgaaa aaagctgatt atgtcactgt ttcaaatgat aaagacggag
     1141 tatctcaagc atttgaaaga attcttacca tataaactaa ttaaggtagt atagaacata
     1201 gaattctaaa tacggaaaaa tggagcataa attccagtac aaatagtact tcttcagtgt
     1261 caaacgaagc gaatataaca tagatattta ggattgtgac aaaaatcatg tcacaatctt
     1321 tttttcgaat aaacttattt tttgaagtcg gccatttatc gtaatttctt tgcataatac
     1381 gaacaaattt tcggttattg atgaaaaaaa acattgaaaa tggtatgata aaagaaaaaa
     1441 aggaggaaat ttttaatggt gaaatttatc catgcggcag atttacatat ggatcggtca
     1501 tttgaaggac tgacaactct tgataaaact gtacaggaaa aactattgaa gacgaatctg
     1561 accgttttat caaatatcat tgaacaggca ataataaata acgttgattt tgttttactt
     1621 gcaggagata attttcatca aaatcgtcct tcattaaaaa tacagaaaca tttttcagaa
     1681 cagatgaaac ggttagaaaa gaaccatata cctgtattta taatattcgg aaatcatgat
     1741 ttctatcaaa aagagcggta ttggttctcc tttcctaaaa atgtccattt atttacatcc
     1801 gaaacggtag agacaaaaaa aataacgata aaaagtggag aaactgtctc tctcagtgga
     1861 tttagttatc gtcaaccgtg gattcaaaaa gacaaagtga tggaatttcc ttctagagaa
     1921 ctcacagatt accatattgg gttgtaccac ggggaacctg gcgtctctca aaaaggaaac
     1981 tatgctcctt tccaaccctc aaagatgcaa gaaaagggat acgattattg ggctttaggg
     2041 catatccatg tgccaacggt cttaaatgaa aagcaaacaa ttgtttatcc aggtgcgcct
     2101 caaggtcata ctaaaaagga acaagcttct acatctattc tactagttga attaagtaaa
     2161 ggaagttgcc aaatacatcc gattaaagta gcagaggtct attggaagac aaaggaaata
     2221 tcattgagga aagcaagaac gacaaaagag gtcattgttc acattcgtca gcagctttca
     2281 aaagtagagg atggatttag tttaattgag ataaaattaa aagattatga ccatctcaat
     2341 acagatgttt tggaacggat acaatcagga gagctattag actatttgtt agaggaattc
     2401 tcagatagga taaatgattt ctttatttgg cgtatttctc tcatagagaa tactttttat
     2461 acgaagaccc cacttgctgc ttctgctaaa ttgatggaac agttatttca atactatcag
     2521 acacctcaag atttccaaca aattttaaat gaagtatata gtcatcaaga agcggctaga
     2581 atattgagcg aactgccgga atatcaagaa gaaacacttg aaaaagccaa gcagctgctt
     2641 aatcaagatt ttttatttga ggaggatcag gaatgaagat tttaaggatc gagattgctg
     2701 cttttggaaa atggcgtcaa aaaagttttg acttttattc aggcaatcag ctgatctatg
     2761 ggggaaacga agcaggaaaa tcaacgattt atcaatttat tcaagcaata ttatttggtt
     2821 tcccttcaaa aggccgtaaa aaaaaggatt atacaccaaa agacggctca gcctatggcg
     2881 gcaaaatatg gcttaaacat cctgtatatg gtgaatttgc tgtcgagcgc tacaagcagc
     2941 aaaatcgcgg aaaatcgaag gtgtggctgg gggatcaagt gggaagtgat gagttactag
     3001 aaaaactgat cgcacctttg acgaaagagt tattccagca ggtatttact ttccagcaag
     3061 agcagttgat ggaactagat catttgagag aaaaagagct acatgatgcg ctgatttctt
     3121 taggcatcac gggcagttct caagtattcc aaaagcggca agaatattat cagaaagcac
     3181 aacaattatt caagaaaaaa ggccaaaaat tactaatcaa tcaaaaatta aatgaatgga
     3241 aagagctgca agaaaaaatt catcaaaaac aagaacagga agcttatttt ggcaagttga
     3301 tccaacaaga acaggaatac gagtcgcaac agcagcagtt attggcacaa ttaaaagagg
     3361 cgaacaaaca attttcatta gccagacagc aagaacttaa tttttcttta tatgaagaat
     3421 ggcaatctct caaaaaaaac agcactacag gtcttcctga tgagcaactt cttttagatc
     3481 tggagtcttt ctccaaacgg tatcagcaaa caaatgagcg tttggaagaa ttagaagcaa
     3541 cactggaaaa gcatagcggg atggatcagc agtcagccag atattatttt tatttagagc
     3601 aggagcagga actaaaagat ctccagcaac ttcaatttac agcggaacaa ttaaacgaag
     3661 aatggcaaag attacaaatt gagactagag aaacaaattc agaattgaag attttggaac
     3721 aaaggtggca ttggcagaaa aatccgttac cggaagaatt tttatatgaa gaagaatgga
     3781 agcatcttct ggctgaagaa agaaggattg ctgatctaga aagccagatt tctgtgcgtc
     3841 tccaaatagc taaagaacag caagagatga ttgaagcaga agtgaatgac ttggaagaga
     3901 cctatccagc attattacaa aatcagtcag agatagcacc agtctcttca tctaaaccgt
     3961 atatgctgat ggctggcgga gcaataatca ttgcaggtat atttgtacca atgcccttga
     4021 aagtgatcct tttactaatt ggtgcaggca tgattggcta tttcttctac aaaaggcaac
     4081 caaaaattaa aactaaaaat gatttctctg agataaaagg aatgtggcaa gaaaaactag
     4141 gacaacttga tctagcctta gctcaattag ctgaagcaga agaaaaacaa aagagaactg
     4201 gagaagaaaa acagattctt cagcaagaag tatatcgttt tgcggatcat cggcacttag
     4261 gaaagatgga tacgctcaaa ctcatgaaag aatatggaca ggaagtcata gattatcaga
     4321 aattatatgg cgtatttgag cggaaacata aaagagaaca ggaaatacaa gaaaaactac
     4381 gacaaatcga ccaaaaattt gagtttgtta aagaatggtt accgatacaa gataagacaa
     4441 tttcagaaaa aatggtattg ctttcccgtt ttatacaaga gatggaacag atgaaatttg
     4501 ccagaagcta tcagcaaaat actttattga agcaagaaat caatcaattg aaaaagaaac
     4561 aaaaagtatg gatacaagaa tacagcgaac aattgactca agcaggctta tcttatcctt
     4621 cggaagtacc tgtcttttta caaaaagcca aacaagccga acagcagatg aaaagataca
     4681 atgaattatc ggaaatgctt actccactat ttcctgaaga gctgacaaaa gagaaattat
     4741 ctgtaagact gcgccaactg aaagaaaagc aatcccaact ccagcaagaa gaaaaagaag
     4801 caagtgaaaa tcggcaacga ctccaacttc aagtagaaga gttgcaaaga gacggcacat
     4861 tggacgaact ttatcaacaa gctagccggc aaaaagcaaa attacaggaa ttactggagg
     4921 aatggggagc acttgaaatc gccgggacat tcttaggtga tctttcaaca gagatgagtg
     4981 aaagacaatt accccagttg ttaagagcag caggtgatta tttaggtatt ttaacaaaag
     5041 gaaattatca gaagatatta ctgaaaaatg atacactgac tttaacagac ggatatacag
     5101 aatttcccat ctatgagtta tctacaggta cgaaagatca gctgattatg gcgatgagat
     5161 ttgcttacct ctcattagaa gctaaccgtt cgatatgccc gatcatcatt gatgatggct
     5221 ggcttcatta tgatcatcag cgaaagtatc aattagctga acttttagct aaatttggag
     5281 aaaagtatca aataatttgt ttttcttctg ataaagaaat ggtaagctat taccatgaga
     5341 tgaaccaaat cgtaaaacaa ttagaaggag caaataatga aaaaaattcg tgatttagta
     5401 atcgatgagc agtttgaaca atttgtcctg atcaaaagtg cagatgtaag aatcgctaaa
     5461 aacggaaaaa aatttattgc ttttactttc caagatactt caggtactat cgatggtaaa
     5521 tactgggatg cttcggagga ggaaatcaat aaatttacag ccggcacagt cgtttttcta
     5581 aacggtaaaa gagaggttta tcaaggaaac cctcaagtaa agattcttca tatgcgctta
     5641 acaagggtag atgagccagg agagcctagt ttatacatgg aaagagcccc tttgaagaaa
     5701 gaagaaatgg aagaagaaat caatcaattg ttgtttgaga tcaccaatgc gcattggaat
     5761 cgtattgttc gctatctact taataaatat caaaaacaat tttttgagtt tccggcagca
     5821 aaaagaaacc atcatgcatt tgccagtgga ttagcttatc atactttgac aatgcttcac
     5881 ttagggaaat caatcgccga tgaatatcct gagctgaatc gagcattgtt gtatgctggt
     5941 atcattttgc atgatttagg aaaggtgatt gaactttccg gtcctatgtc gacagaatat
     6001 acgcttgcag gaaatttgat cggtcatctg gtattgattg acgaagaaat aactaaagcc
     6061 tgtcttgcgt tgaaaatcag cgaagctgac gaagatgttc tcgtattacg tcatatggtt
     6121 ttagcacacc atggcttatt agaatatggc tcacctgtac gtccaagaat aatggaagca
     6181 gaaatattac atcaaatcga caatatcgat gcttcgatgc agatgatgtt gacttcgatt
     6241 cgtcaaacag aaccaggaaa atacaccgat cggattttcg gtatggacaa ccgaagtttc
     6301 tatgtaccaa aagatttata gcaaaaattt atttttttca ttcaaaacaa aaaaagcgag
     6361 acataagtct tcgctttttt tgttttc
//
LOCUS       DADQDV010000116         6387 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.120, whole genome shotgun sequence.
ACCESSION   DADQDV010000116 DADQDV010000000
VERSION     DADQDV010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6387
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.120"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(560..1600)
                     /locus_tag="J8S10_002819"
     CDS             complement(560..1600)
                     /locus_tag="J8S10_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HAZ9631358.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLL
                     KDRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGR
                     VNKRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTT
                     VIAKIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVD
                     IMKEDSINTFVPENVLNLIKTFSSTYEDAQKTVQTIHNAKKKAEELEQTVVVYEELES
                     YGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFN
                     ELPTVSTENWLE"
     gene            complement(1949..2275)
                     /locus_tag="J8S10_002820"
     CDS             complement(1949..2275)
                     /locus_tag="J8S10_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631359.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNFKSKEVEEIELTKKNISKVIKD
                     QGSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLA
                     KKQNKI"
     gene            complement(2262..3050)
                     /locus_tag="J8S10_002821"
     CDS             complement(2262..3050)
                     /locus_tag="J8S10_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAZ9631360.1"
                     /translation="MARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVDIDPQG
                     NATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAEREFTQVG
                     SEHRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLKGLIKL
                     SETIETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKTYIRRT
                     ITVDEAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
     gene            complement(3482..>6387)
                     /locus_tag="J8S10_002822"
     CDS             complement(3482..>6387)
                     /locus_tag="J8S10_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HAZ9631361.1"
                     /translation="LHEKDLELMETIRRPATRLGFALQLVSLRFLGTFILDLTNIPQN
                     VLSYVATQLNIDPGEIIYYSRRQTRYQHTKLIKSHYGYQDFNQPEIETYLANWLLNRA
                     LYTTESSDMLFDMLLKKCLDEKIVLPGITTFSRFVASAIEKAEEHLYRQLSLVPTEDE
                     RKRLLNHLELIGTPVYGAIIKMDILRTPLADDSHKEIARGFDRLKQFQAFSTEKWKME
                     SIPEGKIKVLANYAFKAKAQLIQRMSEQKKLALLVAFIFIYKRKAMDEQILALSNFFE
                     TVFRRAKNKESKERLRTIKDLDRAASTLSDIVDLVMSSHSDTNELSLRDRILEKYSEE
                     NVTEAVSQVRLLVKNDREPIAISELLNTYRKFRKFIPDILTTLTFDSNDYGNNCKELW
                     TFINNRFPKPITYKMFGAIKHTLPKKWIYYIHEYPEQTNKCVLIAAVELLIQSLKRHD
                     IYIPQSVLYNNPMDCLIDEKTWVQQKYVLLEQLDLPSSANEMSLWLKNDLELSYKEAL
                     NRWPTSKMARIENADRLVVSRLKKTYEKKEDKSFRRRIQQLLPKIDLSDLLLEVNQQL
                     NLTQSFNHLSDKDTKMKDLDISLLAVLLSESCNIGFSPVSKEGFDSLKYDRLVYVNHH
                     YIRVDTLSGANQKIIHAHRKLATSKIWGDGHMASADGIRYITPQRSLYSRSNPKYFGR
                     GRGITFYNFVSDQYIGFHGMVVSGTLRDSLYLLEGFLNQPSELTPNQIMTDTAGYSDM
                     IFGLFGLLGFQFSPRIANDKGTKLWRIDANAHYGELDTLSQNSINMELIYTHWEDILR
                     VAGSLKSGKVNATELTKSLQRNGQPTPLGKAITEYGKVYKTKHQLRYISDEIYARQIL
                     EQLNKGEARHALCRNIFYGRKGKLYQTYYDGMEEQLNALGLVTNAIIYWNSLYLEKVF
                     EQMKAEGFDCSEEMIRRQSPLISDHINFVGKYTFRYEAELSNGKLRPLNVEEF"
BASE COUNT         1948 a         1119 c          995 g         2325 t
ORIGIN      
        1 ccgttgcggg taataccgta acactgaagg gcacgcatta aggcgtcatc ttaatgcttt
       61 cctgtaggac actgacggag attaccagtc tcccgagcct tacaggggcc tttctttttt
      121 ttgtattttc aattatcaca atttatcgtc caaaagtgca gaacgaaaat caattcatca
      181 caagcatatc agacaattaa atttaaaaca actaaaaata tacaaaaaag tgtaattgaa
      241 tattagcagc actgcctgaa aagaagtaat atcaggcttt tcagcttggg gaaataagtg
      301 aattacctct cttcatgaat tattataact caaaaaagca catatgcaaa cactagttcc
      361 ctattttttt gaatgaaaaa taactaaaat atctaacgat tatgacttta aaacctacgt
      421 ttgtgattgt tttcataaac ttttaatcta aaaactccgg aataatagct atttatttgt
      481 aacatttgta ataaaattaa aatcataaaa aagttctaat ttaaaattga tcatttttat
      541 agtgatcgct ttttatcaac tactctagcc aattttccgt actaactgtt ggtaattcgt
      601 taaatgtttc tctttgttcg tttgcaagct ttgccgcaat agctttttcg acaaaccaat
      661 tttttacata aacgaaaatt agattctgca aattgtttac tttttcagtt ttttgttttt
      721 gataagcttt cagcaaagtc atatataatc ctttgtcagc atcaattcca taagattcca
      781 gttcttcata aacaacaact gtttgctcta attcttcagc ttttttcttt gcattatgaa
      841 tagtttggac ggttttttga gcgtcttcgt aagtactaga aaatgttttt atcaagttta
      901 atacattttc tggtacaaat gtatttatac tgtcctcttt catgatgtcg acgaagttat
      961 ctagtaaaac ttgattttgt aactgatcag tttcagtgtc tattatgtgt ctattagtgt
     1021 ctatagaatt agaatagaat agattgtctg cgattttcgc aattacggtt gagtccttga
     1081 tatgactgga ttttgccgta tttgcgattt tcgcaattac ggtggtatca ttgatttctc
     1141 gcggttttgc cgtatttgcg attttcgcaa ttacggtggt atcagtattg tcttcctctt
     1201 ccatgatttt aaagacgtct tgattcgtta cttctggctt gcctaagtac aataaattag
     1261 gcatggattc aatcttaccg tcacgtttat ttactcttcc tctcttctgt ttcagaagac
     1321 ctgctttttc taattccttt ttgattttag atactttacc ttcgcggcat tgtaacaatt
     1381 tcattaattc ttcaactgtg aatatgaaaa atatattatc atcagaatct acccagttat
     1441 ttttgactga ataatcaaat cgatctttaa gtagcatata agcaattttt gcatcatttg
     1501 atagatccat gtatttttcg ttagtaaaaa ataccttagg catttgataa tatttttcac
     1561 gataaatttc ttttgatttg taataattaa aatcattcat agccaatcct ctttctgtag
     1621 gatagcgttt tgttcaaaac tatgttacaa tgaattaaac aaatatatct atccactata
     1681 tatttttcta ctgctgataa gtcgccaaac tttgttaaag cagtagtctt tttttatctt
     1741 tttttagttt accttaaaaa ataaattaaa gcaaaccgct ctatttcaag gtttaagctc
     1801 atagtaacta tatcacgata ttacaataat attatatcac gatatcgtaa tattacaata
     1861 tgaagataag cgacttatca gctttgatac tactgatttt tataaaaaaa atatcacgat
     1921 attatgatat cgtgatattg aatgtaaatt aaattttatt ttgtttcttt gctagtttat
     1981 atccttcaat caagtattct tcaggtatgg actttaatag cgcatcttct ataacgtctg
     2041 gtttactttt gtctgattca gcaatagtcg tccaatattt gagtgctgac attagaattg
     2101 gatttatacg aatgctatct gctgttctta cactacttcc ttgatctttt atgactttac
     2161 ttatattttt cttggttaat tcgatttctt ctacttcttt tgatttaaaa ttctttttat
     2221 ttttatttcc tagtaatcta cttactgcag cttgactgcg attatcttct gccatcaaaa
     2281 tcaccaactt cttttaaata ttcttctgta aatgctttat agtcatcttc agctgttgag
     2341 ggtttattaa aattgattag atctgatcca gcagcttgcg cttcgtcaac ggttattgtc
     2401 ctacgaatat aagttttgaa aatttttgca ccaatgactc tagaaatttc ggttgctgca
     2461 gacgtcattt ctttagaaat gttataacgc ttattatact tagtaaatag aactcctcgt
     2521 acttcaagct tgtcgttcgt atattctttt accgtttcaa tagtttcact taactttatt
     2581 agtcctttta atgagaaata cgcagcttca actggaatga taatttcatc agaaacagta
     2641 aatgcgttga ctgtaagcat tcctaaactt ggtggacaat caattataat ataatcatag
     2701 ttgtccttga ttggttgaag tactctttta agcctgtgtt cacttcctac ttgagtaaat
     2761 tccctctctg cagaagaaag ggctatgtcg gctggcaaaa catcaattcc tttatagtcc
     2821 agaatagcat ctgtaatgtc agcctcccct tttaatactt cataaattgt aggttggttt
     2881 gttccatcta tatcgaaacc tacattatct gtagcatttc cctgaggatc aatgtccact
     2941 aaaagtacat ttttaccgta aacaaatttc aaacatgctg ctaaattaac gctagtcgta
     3001 gttttagaaa ctccaccttt ttgattggct actgacaata ttcttgccat taaaatatcc
     3061 cccattcatc ttatattata atataattat atcataatat tgtgatattg caatatcgta
     3121 tatgcattat attgtaatat tgtgtgatta ttttgtttta aagatatata tcggttcgga
     3181 tataaagatt attcatatgt tattcgaaat taaaataatc actttttatt actttaaaat
     3241 tttttattaa tgataagaaa tatgttttgc gagcagcaac tagaataatt taaacattac
     3301 taaactgtct atattgtggg gtacatggaa catagaaacg aaatagtgcg gtagcacaaa
     3361 agtaaaaaca caagaaacgt tgatttaacg ctgttctcgt gtttttctct ttttctattc
     3421 gaagtgattc gctggaacag tcatacgaaa tagtgcggta gcatgcaaaa cccgaacatt
     3481 gctagaattc ttctacattc aatggacgta acttaccgtt ggataattca gcttcgtatc
     3541 taaacgtata cttaccaaca aaattgatgt gatcactaat tagtggagat tgcctgcgta
     3601 tcatttcttc ggaacagtcg aatccttcag ctttcatttg ttcaaatact ttttctaaat
     3661 acagtgagtt ccaatatatg atggcattag taactaatcc taatgcattg agctgctctt
     3721 ccatcccatc ataataagtc tggtagagtt ttccttttcg tccataaaaa atattacggc
     3781 ataaggcatg ccgagcttcc cccttattca attgttctaa aatttgccgt gcatatattt
     3841 cgtcagaaat ataacgaagc tgatgtttcg tcttataaac ttttccatac tcagttattg
     3901 cttttcctaa aggcgtgggt tgcccattcc gttgaagaga tttcgttaat tctgttgcat
     3961 tcacttttcc agatttcaac gaacctgcaa ccctaagaat gtcctcccaa tgggtataaa
     4021 tcagttccat attaattgaa ttttgagaca acgtatcaag ttccccgtag tgagcgttag
     4081 cgtcgattcg ccaaagtttg gttcctttat cattggcaat tcttggacta aattgaaacc
     4141 ctaataagcc aaagagacca aaaatcatat cgctataacc agctgtatca gtcatgatct
     4201 gattaggagt taattcgctg ggttgattga ggaatccttc tagaaggtaa agcgaatctc
     4261 gcagtgtccc tgaaacgacc attccgtgga accctatata ttgatcagag acaaaattgt
     4321 agaatgtgat cccacgacca cggccaaaat attttggatt acttctagaa tatagggaac
     4381 gttgtggtgt gatataacga ataccgtcag ctgaagccat atgcccatca ccccatatct
     4441 tagaggtggc aagtttcctg tgtgcatgta ttattttttg attagctcct gaaagtgtat
     4501 ccactcgaat ataatgatga ttgacataga caagacgatc atactttaaa gaatcaaatc
     4561 cttcttttga aaccggggaa aaaccaatat tgcaggactc tgataaaaga actgctaata
     4621 aactaatatc caagtctttc attttggtgt ccttgtcact taagtggtta aatgattgag
     4681 taagatttaa ctgttggttt acttccaata acaaatctga caaatcaatt ttaggaagta
     4741 actgctgaat gcgacgtcta aaagacttat cttccttttt ttcatatgtc tttttaagtc
     4801 tagagacaac caggcgatct gcattttcta ttctggccat tttagaagta ggccaacgat
     4861 ttagcgcttc tttataagac agttccaaat cgttctttaa ccataaagac atttcatttg
     4921 ctgaagaagg aagatctagt tgttctaata aaacgtattt ttgttgaacc caagttttct
     4981 catcaatcaa gcaatccata ggattgttat ataagacact ctgaggaata taaatatcat
     5041 ggcgttttaa agattgaatt aacaattcga cagctgcaat caatacacat ttattagttt
     5101 gttcagggta ttcatgaatg taataaatcc atttctttgg aagagtatgt ttaatagctc
     5161 caaacatttt gtaagtaatc ggcttaggaa atctattatt aatgaaggtc cagagttcct
     5221 tacagttgtt accgtagtca ttgctgtcaa atgttagtgt agttaaaata tccggaataa
     5281 attttctgaa ctttcgataa gtgttcagaa gttcagaaat ggctattggt tcacgatcat
     5341 ttttaaccaa tagccgaact tgcgatacag cttcggtaac attttcctca gaatattttt
     5401 ctaagatacg atcgcgaagg gatagttcat tagtatcaga atgactggac attactaaat
     5461 ctacaatatc tgaaagtgtc gatgcggctc gatctagatc ttttatggta cgaagacgtt
     5521 ctttagattc cttatttttg gcgcgtctaa aaacagtttc aaaaaaatta gatagtgcta
     5581 aaatttgttc atccatagcc ttacgtttgt atatgaaaat aaatgccact aacaacgcca
     5641 gttttttctg ttcactcatt cgttgaatta attgagcttt agctttaaat gcataatttg
     5701 caagaacttt tattttccct tcaggaatag attccatctt ccatttttca gtagagaaag
     5761 cttgaaattg ctttagtcgg tcaaaacctc tggctatttc tttatgacta tcgtcagcta
     5821 acggggttct caaaatgtcc attttgatta ttgccccata aactggagtt ccaattaatt
     5881 ctaaatgatt gagaagccgc tttctctcat cttcagttgg aaccaaagac aattgtcggt
     5941 ataaatgctc ttcagctttt tcaattgcac tagcaacaaa acgagaaaaa gtagtaattc
     6001 caggtaaaac aatcttttca tccagacatt tttttagaag catatcaaac aacatatctg
     6061 aagattctgt tgtatacagc gctctattta aaagccagtt agctaggtat gtttctattt
     6121 ccggttggtt gaaatcttga tatccataat gtgattttat caattttgtg tgctgatacc
     6181 tggtctgtct cctgctatag tagataattt ctccaggatc aatatttagt tgagttgcta
     6241 cataactcaa tacattttgg ggaatattgg taagatctaa tataaaagtt cctaaaaaac
     6301 gtagtgagac taactgtagt gcaaaaccta atctagtagc tggtcgtcgt atagtctcca
     6361 tcaattctaa atctttttca tgcaaat
//
LOCUS       DADQDV010000117         6359 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.121, whole genome shotgun sequence.
ACCESSION   DADQDV010000117 DADQDV010000000
VERSION     DADQDV010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6359
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.121"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(287..619)
                     /locus_tag="J8S10_002823"
     CDS             complement(287..619)
                     /locus_tag="J8S10_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HAZ9631362.1"
                     /translation="MSYTGILSLEDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYAGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIS"
     gene            complement(1466..2506)
                     /locus_tag="J8S10_002824"
     CDS             complement(1466..2506)
                     /locus_tag="J8S10_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HAZ9631363.1"
                     /translation="MTDFNFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCSVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFIPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAETESGISIIFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNSE
                     SFPKTITKDWLE"
     gene            4318..4536
                     /locus_tag="J8S10_002825"
                     /pseudo
     CDS             4318..4536
                     /locus_tag="J8S10_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            4796..5050
                     /locus_tag="J8S10_002826"
     CDS             4796..5050
                     /locus_tag="J8S10_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAZ9631364.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDTIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            5051..5368
                     /locus_tag="J8S10_002827"
     CDS             5051..5368
                     /locus_tag="J8S10_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAZ9631365.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            5927..>6359
                     /locus_tag="J8S10_002828"
     CDS             5927..>6359
                     /locus_tag="J8S10_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631366.1"
                     /translation="MNILNEKRYVWFAGKKYITTFKRLSELMQQTVKSAMPEGYKFNF
                     VQSSVSTESIYFSILSESRLFHFRISSHVKKTDVDIYTFRTNNYKNLNDLSRSISEYL
                     KGNSYLKIRFSHILILLPYLNENFTLIQVDKSFIASGNQGNM"
BASE COUNT         2187 a          967 c          969 g         2236 t
ORIGIN      
        1 taggcgctat tctaacttgt ctaacttcta aattccctct tgtttactct gtgcatatta
       61 tttacacaaa ttcatttcac cactatccaa acaagggcat ttactcgatt gaccaatttt
      121 ttacgttacc aatcgtaaaa acctaccccg tcaccccccg aaaggaattg ttgatagatc
      181 aagtctactc cttatttttc tagtaattct aagttctttt agaagtctcg acaatatttt
      241 caagcaagcg aaaaacgata aaatacaagt tatgagaatg atcaattcag ctgattaaac
      301 gccccatccc ttttgcggta caacgcaaga ctccattttt tcttcgacca atcagtacac
      361 cgttttggtc ataaacatgt ttgattgttg gatatagttc ttttaaaggg ataggatctt
      421 ttaaaattat ttgcttttgt ttaccagcgt aataaatcat ttcctctgag actttgtctt
      481 tctggattat atatttctta cactgcacaa cggttttact ttggccagtt gatagtttct
      541 tcgtgatttt ctctgtagcg gtacaccgtt taccgtagtg acaaatatct tcgagactca
      601 aaattcctgt atatgacata aaataatcca cccacttact ttaaatattt ttaataagtt
      661 tttcttgtta tttttcaaaa atagagaatt gattttcgtt catgacaaac aaaaaagagg
      721 gaacgcatcc aaacatgcgt tccctctaat ttcagcgttc gtcatacggc aaagagccac
      781 acggacattt ttataacatt atgcttaggc atagattcat cgtaatatca cgtattttta
      841 accttaacac agccaaaaaa agtggtatca cttttgaata tctgttatac taaatccgtt
      901 gcgggtaata ccgtaacact gaaaggtaaa cgcattaagg gattaaaggt tgtcttaatg
      961 ccacctgtgg acgtcgacga aggttaccag ccttccgagt ctcacagggc ctttcttttt
     1021 tttgtatttt caattgtcca aatttatcgt ccaaaagtgc agaacgaaaa ttaattcatc
     1081 acaagcgtag cagacaatta aatttaaaac aactaaattt atacaaaaaa atgtaagcga
     1141 ataatattcg tattgcctga aaagaagtaa tatcaaggtt tttagctttt ttaaaaaatg
     1201 aaattacctc tcttcgcgta ttattataac taaaaaacag caacatgcaa acgtttgttc
     1261 tcttttttgt gttggaaatt aattattaac tattaacact tatgacgtaa aaagctacgt
     1321 ttgtgatttt tatcataata ttttaactca taaattctat taaaatagct atttctttgt
     1381 aacatttgta atataattag aataataaaa aatttttaat tttaatgcta ctccatgaag
     1441 caacaatcaa tttgtcagtg aaatttcact ctaaccagtc tttcgtaata gtttttggga
     1501 agctttcaga attcaaacgt ttttcacttg atactttagc agctattggt ttttcgataa
     1561 accaattttt tacatagaca aaaatcaggt tctggatatt ttcaactttt tcggttttta
     1621 atttttgata ggcttttaac agtgtcgtgt ataattcttg ttctgcattg acataataac
     1681 tatcgagttc ttcaaaaatt attgaaatac cactttctgt ttcggctttt ttctttgcat
     1741 tatgaatagt ctggacagtt ttttgagctt cactgtaact tgaagaaaat gtttttatta
     1801 aatttaatac tcgttcaggg ataaacgtag caatgctgtc gtttgtcata attgtctcaa
     1861 aattgtctaa caacaattga tcttgtaggc ggtctttttc agtgtctata ttgtgtctat
     1921 tagtgtctaa tatattatta ttaagttctg gtatgatttt cataccctct gatttatcaa
     1981 cgttttggca cggtatgatt ttcataccct cttgagcccc aagggattca gcgtctgatt
     2041 tttcgtcgag ggtgggtatg attttcatac cctctgattt atcaacgttt tccctattct
     2101 ctctatcaaa tttttcgagt aagtagatat cattttctga gacttttaat tctgctagat
     2161 atagtctatt aggattattt ttccctaact gtttgttaaa tcccatctgc ttttgtaata
     2221 ataaaccaaa ggattccaac tcttttttga ttgctatcgc tttttgtttt tggcagttta
     2281 atacgctaca tagttcattt gtcgtataag taaaataaac attaccttct tcatcgattt
     2341 gccgtttgct gattgcgatc tctaatcttg cttttaaaag catataggca atcttagttg
     2401 aatctttcat ttttttgtat tcgtcagaaa caataaagac ttttggaaat tgataaaata
     2461 attcgttgta aactctatcc gccttaaaaa aattaaaatc agtcattgta gatcctctac
     2521 tttcacgttg ttttatttat gtaaaattac ctactctttt cgaaaatagc aaagataaat
     2581 aaaaaatgca aacgcattaa aactgttttt taattaaata ctacctaaaa tcagaaataa
     2641 aatgaattat gtactacctt taaagtcatt aagaactact ttaaataaat attatttata
     2701 attaaatact accagaagaa cgtatgaata aaatttagtt ttaaaattaa agataattaa
     2761 gtactaccag tgtcaaaaca aaaaataaat taagaactac cttatgcata taaaacatac
     2821 taccattact agtaatatat actaccttat ttcagtagta tatattatat tcttcttata
     2881 agacaaggct ttaggctaga aaacaataga ttatatacta ctaaaaaata caataagtac
     2941 taccaatgtc agatatatat aataattatg tactaccatt aaaattaact tatttaataa
     3001 gatactactg tgttaatctg aaaaaaatta ctttaaagta gttacatact acctgttaaa
     3061 ttagatacta ccattaatac ttaaattaga tactacctat atttatatta agtactaccg
     3121 ttctaggaat aagataataa aaaaaaacta ccaaattgca attaaatact acttaaaatg
     3181 taaaaaataa gaactaccca aattaggtag ttcttaataa gagaatatca gataaatttg
     3241 tacaagtcat aaaaaaatta atcttaaatt tttaaatata tatacctgtt aattataaac
     3301 tactttattt aggtagtaca taattaacag ataaaactac atgcttgtag tttgtctagc
     3361 taatgagttg catatgattt atataaaggt gtgcagcata acttagttga agttaagaga
     3421 atagaataaa tattttttgt tttgctaata attaaacact acctaaatat ggtagtgttt
     3481 aattatataa tattcatttt gttacaaata atcgtattat aaaagcataa caattgggat
     3541 aactattttt tagattattt aagtactact taaattaggt agtacttaaa ttttggttta
     3601 aggtagtagg taattaagaa ataatatata tcttctttta taatagaagg ggagaggcct
     3661 agttaaaaac agcgacaatt aataacaatg tatttaatgc ttcacaaaat ccatttggtg
     3721 gacaatgcat tgttattagc gatgatctac cgttctaagt agttttttct attggttgca
     3781 ttcgtgacta attatggtat aattatgagt aacaaagagg tatttcatta tatcatcaaa
     3841 ccccatcagc gtgtaggctg atggggtttt ttttacgttt ctatattata gaattaactg
     3901 gtaggcttac tgtctttttt ggcaattttg caatcaagcc acttgcagat gtagtgtgca
     3961 gttacctctg caaatggctt gattgcaaaa acaaaatcaa aaaggtattt cattatatct
     4021 cctcctcccc ttgccagatt aggccggggt agcagacagc aaaactatta taacataact
     4081 gaaataccta aatgacatat acagatatga taatttatgt attgattttt ctaacaaaag
     4141 cacatatttt aatatatact acctatttta ggtagtatat atttttagat acaatatcga
     4201 tcagttttga ggaaatgaaa ttctagatat tttttgctac atagagttac tttcaatatt
     4261 ttttaacgta attaggcaga agtcactcat cctctatagg tttgtgatga aattgctatt
     4321 gatccattta agtaagagca aaaaactgga ggtttatcag gtaattggtc taatggattt
     4381 aagtatgcgg tcaccgtgta tagagttgct tatgagattc aagaaaataa agttattcca
     4441 gtattgctat atggaacaca taacaatttt tatgaattag ccgagaacac tcgcaacttt
     4501 attcgtgtag atgaatcggc ttcggttgag ttataacttt agctatatca atcaaccgac
     4561 cgacatatgt taaatctata tataataaaa atacctactt aaatggatgt taacggaagt
     4621 gtatggtgag tagttcactc gtattttgat atcgtttgta tatgttttca gcgttctaag
     4681 tggcttattt tgtccaataa taatatggag tggaatccct taagaaacac cgttggcaat
     4741 tgtcgttata acatgttata atttatttat caaaaactaa aagaagtgtg ataacatggg
     4801 aaaagaacta aaggttagaa agatcggcaa tagcgtggga gtgatccttc caagctctct
     4861 tggattaaaa agcggagaca ctatccaagc caaacaagaa ggcaacttat tcatattaga
     4921 tactactcaa atagcaaaag aacacgatcg caaattgatt gaagaaagtt tccaagactt
     4981 tgagaaaggt ttaacagttt cagaaattga aatggtaaaa gctttcggaa aatacggctg
     5041 gagtgaatag atgaaagagt acacgctagt ttattctaaa agtttccaga ccagccttga
     5101 aacgataata gaagaatggg aaaatgagct tgctctttct ccagccagca taaaaagatt
     5161 tgtaggtgcg atccagaagg ctttagaact aaccaaaaat tttccaacta tgcatgagga
     5221 agtttccgaa atctatggaa tggatatccc aacatatcgg atcgtgatcg gcaaaagcta
     5281 tgccttattt tatcggatcg accatgaaaa aaaagagata cttgtaggac gtattttcca
     5341 atctaaacaa atgaaactag gcttttaaca ataattaggc aaaagtcgct catcctctac
     5401 aggtgggtga ttaatgccgc tcgatatggt tgttaaccgt cggttactcg aagattgata
     5461 tataagactt agtacctttt tattttgctc catgttatgg ccgaaggtct aaagatacaa
     5521 tcattagtct agagaaaaat taagaaccgt aggaactacg gggatcgctt ggtgaataag
     5581 agacactgct attagtgaaa aaataagata tcaagtacgc tctattccca aaaatttcgt
     5641 gactttactc atgagaggtt caagtagtat atttttaatc aaaattgacg taacttttaa
     5701 taaatactac ctaaataagg tagtatttat ttttgtgttt taaaagagga agtccaatat
     5761 atctatggga aacttcttaa atattatgtt ggtacatgaa aatatacatc cctgctagac
     5821 tatttacaac attttacttt gtacgtattc ttgttttaaa aggaatggga taaaatatag
     5881 gtacaataac tatttgatgc taaatataat taatggagga gagatagtga acatacttaa
     5941 tgaaaaaaga tatgtatggt ttgctggtaa aaaatatatt actactttca aaagattatc
     6001 cgagttaatg cagcagactg ttaaaagtgc tatgcctgaa ggatacaagt ttaattttgt
     6061 tcaatcttca gtatctactg aaagtatcta tttttcaatt ctttctgaga gtaggctttt
     6121 tcattttaga ataagttctc atgtaaagaa aactgatgtt gatatatata cgttccgtac
     6181 aaataattat aaaaatttaa atgatttgag tagaagtatc agtgaatatc tcaaggggaa
     6241 tagctatctc aagattcgat tttcacatat attaatttta ctaccatatt tgaatgagaa
     6301 tttcacccta attcaagtag ataagtcttt cattgcctca ggtaatcaag gaaatatga
//
LOCUS       DADQDV010000118         6229 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.122, whole genome shotgun sequence.
ACCESSION   DADQDV010000118 DADQDV010000000
VERSION     DADQDV010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6229
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.122"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            133..633
                     /locus_tag="J8S10_002829"
     CDS             133..633
                     /locus_tag="J8S10_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HAZ9631367.1"
                     /translation="MEQIRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELKGTPIGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCNDMSDVAYYLIVEAGDLGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFELM"
     gene            730..2577
                     /locus_tag="J8S10_002830"
     CDS             730..2577
                     /locus_tag="J8S10_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HAZ9631368.1"
                     /translation="MVGNKWYKCDLHIHSTASQCFQDKKVTAKEWVEECLNKGLDCVA
                     LTDHNTGENIDEYKKVAIENGLDFFPGVELTCGENGTHLLVLFDKSACTNDISDFLTK
                     MGIKREDWASAAACSMKSVLEVIDFAEHEGLLVIPAHIDEFNGISSAKFGNLGKIFES
                     ENIYAVQTVQKEFFENRSQMIPSSKRDTIYDSVNARYDGRVGKDTLESWYKSVVEAEK
                     NNMTFLSFSDNPHSKGNSKHGLWGIGTRYSYIKMKDEPDLGSLRDALMLGETRVHSDF
                     SNFSINENEVLLEKLSFSGTTLSTKEVVVEFSDNLTSIIGGRGTGKSCITRFLVYVLG
                     KEAELDQFSEIQSDYQNFAQIEHNGSGIFLKDTIVKLNIFYKGTKYQIIRTQDRHSIY
                     EFTQENGLVEKETERLRMISDKVSIYSQKQIYEISKNQTSILELLDGYNSDLISEYKN
                     EIETCVNEIRKLNWDIVSVKKEIQDKAKVELEIEDLKKQVEKLSHKSYKDVYDEYSKE
                     TDIYRELKRDVEALKEIPKNLTDSVDKIDFGNGIKVTDEIDEHRGELIKNLVTNRAKI
                     QTIINEMSDEIDSYRAELNKSDWKVNYNEVSKRYQRGIKNLVKSYLKMN"
     gene            2580..3476
                     /locus_tag="J8S10_002831"
     CDS             2580..3476
                     /locus_tag="J8S10_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAZ9631369.1"
                     /translation="MLQNLDSLYQSLSKTEERLEEIIQQEIKLKDYQVEVDSAMSRMN
                     KSYQNLYSERSSSSREIFSDITGIEATIQPNRDFNNYVKELRACINKEDTFDSEFGSL
                     IDKLTKNSITNQDIYNDILDIRVSGESSIFSDKKLINSIRKLNDAQVLELQTLKPNDL
                     VVIRLELNGKKVSLSNASAGQKTSAILSMILAYGNSPLILDQPEDDLDSQLINNLIVR
                     SIITKKENRQILIVTHNANIPVNGDSEWLISMGDSKEISADQCGSVDEPNIKPRICTV
                     MEGGEDAFTNRAKRYGFKQIVE"
     gene            3526..3915
                     /locus_tag="J8S10_002832"
     CDS             3526..3915
                     /locus_tag="J8S10_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAZ9631370.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEEVFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPSTLVRSVNYVSD"
     gene            3902..>6229
                     /locus_tag="J8S10_002833"
     CDS             3902..>6229
                     /locus_tag="J8S10_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAZ9631371.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELVPYNYSFLSPEQKFQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLKEVAKQRIDIQTDALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKSLKKSFFSGLQEFVYGVNHHLMGDFVSLSNEEI
                     RCYSKLEKLMESKLARRFKVRRVTPSDLTYLIEHIYGEKGIPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPNRCLIEEKPRCLRMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEISILNLTSKSENQGLLDPYVIMKKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSDQRGLLQVINELRKDGSPIAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDQEDQSNQKRLRDLEN"
BASE COUNT         2106 a          925 c         1335 g         1863 t
ORIGIN      
        1 gagttttcca aactgattgg cttcttggtg attgctttga ttgcggtagg tctggtcttt
       61 aatgcttctg gtgtgaagga tgtcttactc aatttgttta accgaattgt cggtgcctga
      121 gggggaatca caatggaaca gatacgtgtt tatattgcga accttggaaa atacaatgaa
      181 ggtgagttgg tgggggcatg gtttacccca cccgtcgatt ttgatgaagt gaaagaacgg
      241 attggattaa atgacgaata tgaagagtac gcaattcatg attatgaact gccttttgag
      301 attgatgagt atacaccaat tgaggaaatt aatcggttgt gtggtttagc ggaagagctt
      361 aaaggaacgc caattggtga ggtcgcttca gagattcaac atgccttctt caattctttc
      421 gaggaaatgg tagagcatgt ggatgatatc atctattatc ccgattgtaa tgacatgagt
      481 gatgtagcgt attacttgat tgtagaagct ggtgatttag gcgaagtacc agaacacttg
      541 aagacgtata ttgattttga tgcgtgtggt cgagacttgg agattggcgg gaattatttg
      601 gttacgagtc gaggggtttt tgaactaatg taaatcattt gttagaattg accagaaatt
      661 tctatcgtac ttttactttt ctatttgata tactgaaata gaaaatattt gttgataggg
      721 gtgttactaa tggttggcaa taagtggtac aaatgtgatc ttcatattca ttcaactgcg
      781 agtcagtgct ttcaggataa aaaggttact gctaaggaat gggtagaaga atgtttaaac
      841 aaaggactcg attgtgttgc attaactgat cacaatacag gggaaaatat tgatgaatat
      901 aagaaagtgg ctatcgaaaa tggcttagat ttttttcctg gagtggaatt aacgtgtgga
      961 gaaaatggaa ctcatttact agtcctattt gataaaagtg catgtacaaa tgatatctct
     1021 gatttcttaa ccaagatggg tataaaaaga gaggattggg ccagcgctgc agcttgctca
     1081 atgaaatcag ttttagaagt tattgatttt gctgagcacg agggcttgct cgttattcct
     1141 gcacatatag atgagtttaa tggaatttct tcagcaaaat ttggaaatct aggaaagata
     1201 tttgaatcag aaaatatata tgcagtacag acggttcaaa aagaattttt tgaaaatcgc
     1261 tcacaaatga ttccctcatc taagcgtgac actatctatg atagtgtgaa tgccagatat
     1321 gatggtagag ttggaaaaga tactttggaa tcttggtata aatcagttgt tgaggcagaa
     1381 aaaaataata tgacatttct tagcttttct gataacccac actcgaaagg aaattcaaaa
     1441 catggacttt ggggaatagg cacaagatat tcctatataa aaatgaagga cgaacctgac
     1501 ttgggatcac ttcgcgatgc tttaatgcta ggcgaaactc gagttcattc tgatttttct
     1561 aatttctcca ttaatgaaaa tgaagtttta ttggaaaaat taagcttttc tgggaccact
     1621 cttagcacaa aagaagttgt agtcgaattc agcgataatt taacttcaat tattggagga
     1681 agaggaacag gcaaatcttg tattacaaga ttcttggtct atgtccttgg aaaggaagca
     1741 gaacttgatc aattttctga aatacaaagt gattatcaga actttgcaca aattgaacat
     1801 aatggctctg gaatattttt gaaggataca attgtgaaac tgaatatttt ctataagggg
     1861 acaaaatatc aaataataag aacacaggat agacattcta tttatgaatt tacacaagag
     1921 aatggtctgg ttgaaaaaga aacagaacgg ttgagaatga tttccgataa ggtgagtata
     1981 tactctcaaa aacaaattta tgaaatttca aaaaatcaaa ctagtatact agaattacta
     2041 gatggatata actctgattt gatttcagag tataaaaatg agattgaaac atgtgtaaac
     2101 gaaataagaa aattaaattg ggatattgtt tctgtgaaaa aagaaataca agataaggcg
     2161 aaggtagagc ttgaaattga agatttaaaa aaacaagtag aaaagctatc tcataagagt
     2221 tataaagatg tttatgatga gtattcaaaa gagacagata tttataggga actgaaacgt
     2281 gatgtggagg cacttaagga aattcccaaa aatctaactg atagtgttga caaaattgac
     2341 tttggcaatg gtataaaagt tacagacgaa attgatgaac accgcggaga attgattaag
     2401 aatttagtga ccaatcgggc taagattcaa acaataatta atgaaatgtc agatgaaatt
     2461 gatagttata gagcagagct gaataaatca gattggaaag ttaactataa tgaggtttca
     2521 aagaggtatc aaagaggtat caaaaactta gtgaagagtt atctcaagat gaattaaaaa
     2581 tgttacaaaa ccttgattct ttatatcaat ctttatcaaa aactgaagag cgattggaag
     2641 aaattattca acaagaaata aagcttaaag attaccaagt tgaggttgac tcagcaatgt
     2701 caagaatgaa taaatcatat caaaatctct attctgagag aagtagttcc tcgcgcgaaa
     2761 ttttttctga tattacagga atagaggcta ctattcaacc aaatagggat ttcaataatt
     2821 atgttaaaga gctcagagct tgtattaata aggaggacac ttttgacagt gagtttggat
     2881 ctcttattga taagctgaca aaaaattcca ttactaatca agatatatat aatgacatac
     2941 ttgatataag agttagtggg gaaagtagta ttttttcaga taaaaaatta atcaattcta
     3001 taagaaaatt gaatgatgca caagttcttg aattacaaac ccttaagcca aatgatttag
     3061 tagttatccg acttgaacta aatggaaaaa aagttagttt atcgaatgct agtgctggtc
     3121 aaaagacatc tgcaattctt tctatgattt tggcgtatgg aaattcacca ctcatattgg
     3181 atcagcctga agatgatttg gatagtcaat taattaataa cttaatcgta agaagtatca
     3241 ttacaaaaaa ggaaaacaga caaattttaa ttgtaactca taatgcaaat atcccagtta
     3301 atggtgattc agaatggttg attagcatgg gagattcaaa agaaatatcg gctgatcagt
     3361 gcgggtcggt agatgaaccc aatatcaagc caagaatatg tactgtgatg gaaggtggcg
     3421 aggatgcttt tacaaataga gcgaaacgct atggttttaa acaaattgta gaataacact
     3481 agagggtgag acatattatt atgtccgccc tttttaggag gaaaaatgaa aaaaataaaa
     3541 agctatacca gtatctgggc agttgaaaaa gtcatttacg caatcaatga ttttcagttg
     3601 ccttttcctg tgacttttaa ccaaatggct tggttcgttt tatctttact gtttgtcatc
     3661 gtatttgccc atgtgcctcc actatctatg atagaggagg tctttttaaa atacttaggc
     3721 ataccggtgg ctgtcacttg gtttatgtcg caaaagacgt ttgatggcaa gaaaccactg
     3781 ggatttttac gatcctttat cagctatcac ttgcgattta aggtgacttt tgcaggaaag
     3841 aaagtcaaag aacagaagaa acgatgggat gaacccagta ctcttgtaag gagtgtgaac
     3901 tatgtatccg attaagtata ttgaaaataa tctcgtcttt aaccaagaag gcgagtgttt
     3961 tgcctactat gaattagtgc cttacaatta ctcctttttg tcacccgaac agaaatttca
     4021 agtgcatgat aactttcgcc aactaattgc gcaaaatcgt gaaggcaaga tccatgcgtt
     4081 acaaattgcc acagaaagta gtattcgcgc cacacaagaa cgatcaaaaa aagaaattac
     4141 cggtagactc aaagaagtag cgaaacaacg aattgatata cagacagatg cattagtatc
     4201 catgattggc gatagtcaga ttgattatcg cttttttatt ggctttaaac taattgcgac
     4261 agatgaagaa gtcaatctaa agagtctcaa gaaatctttc ttttctgggc ttcaagaatt
     4321 tgtctatgga gtgaatcatc atttgatggg cgattttgtt tccttatcca atgaagaaat
     4381 tcgctgctat tctaagcttg aaaaattaat ggaaagcaaa ttggctcgaa gatttaaagt
     4441 caggcgagtc acaccgagtg acctgacgta tttgattgaa catatttatg gcgaaaaagg
     4501 gataccgttt gaagaatacg aatttcagct accaaagaaa aagctaaaat cagaaacact
     4561 ggtgaaacgt tatgacttat tacgtccaaa tcgttgttta attgaagaaa aaccaaggtg
     4621 cttacggatg gaacatgaga atcatgagtc gtacgtagcg tatttaacaa ttaatacaat
     4681 tgtgggggag atggaatttc cttcctcaga acttttctat taccagcaac aacaatttac
     4741 attcccaatc gacacaagta tgaatgtaga gattgtgacg aataaaaagg ctttagctac
     4801 cgttcgtaat aagaaaaaag aactgaaaga tttagacaat catgcttacc aatctgacaa
     4861 tgaaacgaat tccaatgtct tagatgcttt ggattccgtg gatgaattgg aaaccacctt
     4921 ggatcagtca aaagaatcta tgtacaaact gagttatgtg gttcgagtga gtgccgaatc
     4981 agtggatgaa ctaaagcgac gctgtgatga agtgctcgat ttttatgatg ataccaatgt
     5041 aaaactagtc cggccctttg gcgatatgat ggggctacat gaagaattct taccctcaag
     5101 taaacgatat atgaacgact atattcagta tgttacgtct gattttttgg cggggcttgg
     5161 ttttggggct actcagatgc taggagaatt agaagggatt tactttggct acaatgtgga
     5221 tacaggtcgt aatgtttacc tgaaaccggc attggcttca caaggagtca agggttcagt
     5281 aaccaatgcg ctggccgccg ctttcctggg ttctcttggt ggaggtaaat cctttagtaa
     5341 caatctctta gtctactatg ctgttttgtt cggtggtcaa gctgtgattg tcgatccaaa
     5401 aggggagcga ggagggtgga aagaaacctt gccagaaatt gcggatgaaa tcagtatcct
     5461 caacttgacg agtaagtcag aaaatcaagg tctgcttgat ccttatgtga ttatgaagaa
     5521 aaagaaagac tcggaaagtt tagcaattga tattctgact tttttaacag gaatttcaag
     5581 tcgagacggg gagaagtttc ctgtgttacg taaagccatt cgaacggtga ctcaaagtga
     5641 tcaacggggg ttattacaag ttattaacga attgcgaaaa gacgggtcac caatcgcgga
     5701 aaatatcgcc gatcatatcg agtcctttac cgattatgat tttgctcatt tgcttttctc
     5761 agacggctcg attacccaat cgattagttt agataaacag ctaaatatca ttcaagtggc
     5821 ggatttggtt ttaccggatg cagaaacgac ttttgaagaa tataccacca tggaattgct
     5881 tagtgtttcg atgctaatcg tcatttccac ttttgccttg gactttatcc atagtaaccg
     5941 agaaatcttc aaaattgtcg atttggatga ggcttggagt tttcttcaag tggctcaagg
     6001 aaaaacgtta tcgaataagc ttgttcgtgc tggtcgggcc atgaatgctg gggtctattt
     6061 cgtcactcaa aatagcgacg atttattaga tgaacgttta aaaaataata tcgggttgaa
     6121 gtttgctttt cgcagtaccg atattcatga aatcaagaaa accttggaat tctttggttt
     6181 ggatcaggag gatcaaagca atcaaaaacg cctgcgagat ttggaaaac
//
LOCUS       DADQDV010000119         6224 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.123, whole genome shotgun sequence.
ACCESSION   DADQDV010000119 DADQDV010000000
VERSION     DADQDV010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6224)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6224)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6224
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.123"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(207..1169)
                     /locus_tag="J8S10_002834"
     CDS             complement(207..1169)
                     /locus_tag="J8S10_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018375965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAZ9631372.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(1171..2610)
                     /locus_tag="J8S10_002835"
     CDS             complement(1171..2610)
                     /locus_tag="J8S10_002835"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HAZ9631373.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            2795..4741
                     /locus_tag="J8S10_002836"
     CDS             2795..4741
                     /locus_tag="J8S10_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HAZ9631374.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKSTFKIDGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
     gene            5005..5877
                     /locus_tag="J8S10_002837"
     CDS             5005..5877
                     /locus_tag="J8S10_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAZ9631375.1"
                     /translation="MLYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKLAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIENRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
BASE COUNT         1986 a         1061 c         1107 g         2070 t
ORIGIN      
        1 cgtccaattt cgtaaaacaa ccgtaacagt tgtgtaaaaa tatcatttta gagcatgaaa
       61 aaaggagtgg atttctccac tccaaaaaag tctaactttt gggggtcact acaagttgac
      121 aactcctttt tgtttacaaa tcaattggat atctacaaat tgtattttct aacgaatttt
      181 atagacatta aaaaattaat ttaacgttaa atacttcctc cagaaagtat tgagattggt
      241 aaaatataat ccttatttgt cttttcgcct ttaatttttt tcagaagaat atcaacaata
      301 agacttgcaa tttcatcaat tggttgtctt attgttgtca attgtgggaa aaatttctca
      361 atgaaagagg taccatcgta tccaataatt tttaaatctt ctgggatatt aagtttaagt
      421 tgatgagcaa ttttcatagt gagaatggct gttaaatcat cagaaacaaa aataccatct
      481 ggtttgtgat ttataatagt tgactttatt tccatttcac gacggatagt agacagatta
      541 ttaggaattt tgaaaatttt tccatttgga ttttgaaaag aaaaacctag tgcacgtaat
      601 tctgtgggag aatccgtgtt atcatttcct gtaatcataa tggtattttg acaaccattt
      661 ttttgtaaag tcttagctgc aagttttccc ccttcaaagt tatctgaaga aacaatggaa
      721 acattaggag ctaaatttct atcaaaagca acaataggtg ctctcacacg ctcataatca
      781 gcaattccaa gattatggct tgatgagatt atgccatcaa cttggttggc ttcaagcatt
      841 tcaatgtatt ctctctcttt agcaggatca ttttgactat tgcaaataat cgttttatat
      901 ccatgtttaa ataactctat ttcgagatac tcaatgagtt cagagtaaaa gatattacta
      961 atattaggaa aaataagacc aataagctga ggtgactttc cttgaagtcc acgtgctaaa
     1021 ttatttggtt tataaccaag agttttcata gcttcatgaa ctttttgttt tgttttttct
     1081 gataaatatc ccttattatt aatgacgcgt gaaacggttg ttgggctaac tccagctaat
     1141 tcagcgacat cagttaattt tgctaccatt ttaatatttt aattcaaagt attttccagt
     1201 aggttcgcct gatttgattt gaataccatt ttggtgattt tcagggaata cacgactagt
     1261 aaacactttt tctcctttat taataaaaat ctcaatgatt gagttatcta caaaaatgtt
     1321 agcagttgtt tctttagtat caattgagca ttcacgaatc gtaccaaagt cagtggcata
     1381 ttgaatgcct gctttgctgc gatctaaaat aatttttcct tctttggtat ctacaatcaa
     1441 gctaagtcca tttcctttac tatcagagaa aagaagtaac tccgatttct gatttggagg
     1501 aaaagttagt tcaagctcat aagtattatt tgtttctgct tttgctgtaa attgttcaga
     1561 actagcacgt aatgatgtaa tagcttctac tggatattgg taaagtttac catcttttat
     1621 tgaaagttct tttacaagac tcattgctcc ctgataatca tacttatcag ttggataatc
     1681 gatatcaggt agtccaatcc aactgacaat cagagcacga ccatcaggag tattgaatcc
     1741 ttgagtcgca tacgcttcaa atccataatc aagattttga atttctgaag cgcccacaag
     1801 ttttactttt tctatgtcaa gcgattgaca gatcttaaaa gtattcggat agatattccc
     1861 ataatttagc tcagatttat ccaacccttg aggacaataa atgagaacag gttttttgtc
     1921 tacaaatact agatttggac actcaatcat gtattctgaa ccagtgccgc caaaatcaag
     1981 gttgccaact tcctcccatg tttccacgtt attgtcatcc gctttgtaaa gtttgataaa
     2041 gcctgatttt tctaaatttt gtgctccaac aatcgcatac aattgtcctt cataattaaa
     2101 catttgtgga tcacgaaaat gatcagttac atcagcaggt ttatgaataa gaacattctc
     2161 acctttcgta atgttgtagt ctttatccat ccatgctccg atttgaagtg tatcacgttc
     2221 ccaattttca tttcgaacgt ttcctgtata gagtaagaat agattcccct ctatttcata
     2281 tgcagaaccg gaataagcgc cgtggctatc tcgttttgtg tctggaagaa gttctgctcc
     2341 tgttacatga aaatgaacta aatcatctga ttcattgtgt acccattctt tcaacccatg
     2401 agcagctcca aatggccaat tttgataaaa aagcgtatat tttccgttaa aaaaagaaaa
     2461 accattagga tcgtttaaca atcctgtttt aggttcgata tgatagctag cacgccaagg
     2521 tgatcgtttt acattatcct taattttatc catctcatct ttagtccaat cagaataagc
     2581 acgatatcgt atttctcgag gtaagttcat attttactcc ttcaatttat ctttttacaa
     2641 ctagtatggt aaacgttttc cgttgaaaaa tcaatcattt catttaaaaa aataaactat
     2701 atgacaaacg tttgacatat ttttaagata tgctaaaata aatttgcatt tcagtgaacc
     2761 gttttcacgt aaaaataaaa aaggagtgat tcgaatgaat tacagtaaag tagcttccga
     2821 cgtaatacaa gcggtcggaa aagataacct tattgcagct gcacactgcg ctacacgtct
     2881 tcgtctcgta ctaaaagatg acacgaaagt gaatcaaaaa gctttagacg aaaatccaga
     2941 tgtgaaaagc acatttaaaa ttgatggaca atatcaagtg attatcggtg caggtgatgt
     3001 taatttcgtt tatgacgaac ttatcaaaaa aactggactt tcggaaattt caacagatga
     3061 tttaaaacaa attgctagta aagataaaaa attcaacccc attatggcat taattaaatt
     3121 attatcagat atttttgttc caattatacc tgcccttgtt gcaggtggtt tattaatggc
     3181 attacaaaac tttttaacag ctgctggact ttttggacca aaatcaattg aagaaatgta
     3241 tcctgcgatt gaaggtattt cctcaatgat ccaactgatg tccgctgcac cattcatgtt
     3301 cttaccaatt ttagtaggta tttcagctgc taaacgtttt ggagcaaacc aatttcttgg
     3361 tgctgcaatt ggtatgatca tgacaacacc agatcttggt ggctcaactg aatattggaa
     3421 tatttttggt tatcatgttt cacaaacaaa ctatgcttat caagttattc cagttttagc
     3481 agctgtttgg atattatcta tattagaaaa attctttcat aaaaaattgc catcatctat
     3541 tgactttaca ttcacgccat tattatcagt aatgattact ggatttttga ctttcacagt
     3601 tattggccct gtaatgttat tgttgtctaa tggaattaca gacattattg tttggctata
     3661 taacactact ggatttattg gaatgggtat ttttggagga acatattcac ttatagtcat
     3721 gactggttta catcaatcat ttccagctat tgaaactcaa ttactttcag cgtggacaaa
     3781 tggtatcgga catggagact ttatctttgt agttgcatct atggcaaacg ttgctcaagg
     3841 tgctgcaaca tttgccattt ggttcttaac taaaaattct aagacaaaaa gtcttgcttc
     3901 ctctgcgggt gtctcagcac ttcttggaat tacagagcct gccttgttcg gagttaactt
     3961 aaaataccgc tttccattct tttgtgcttt aattggttca ggaattgcta cagcagtagc
     4021 aggattactt aaagtagttg ctgtttcact tggttcagca ggtttcttgg gatttctttc
     4081 aattaatgca acatctattc cattttacgt attgtgtgaa ttgattagct ttgtagttgc
     4141 ttttgcaatt acttacttct acggtaaaac aaaagctgct ggtatcttta aagcagaaga
     4201 aattgctgaa caaacaccag ttaattcttc aaaagtagca acaacagatc caatatctac
     4261 tgatgttgaa tcaacacaaa caaaagtttc atcagaaaca attgttagtc ccatttctgg
     4321 taaagtgatt agtctttctt cagtaaatga tccagtcttt tcatcagaag ctatgggaaa
     4381 agggattgcc attaaaccaa atggaaacac ggtccattct ccagtagatg gtactattca
     4441 actcacgttt gaaactggac atgcttatgg tattaaatca aataatggtg ctgaagttct
     4501 aattcatatt ggtattgata ctgtatcaat gggaggaaaa ggatttacac aaaaagttac
     4561 tactaatcaa aaagttagaa aaggcgatat tcttggagca tttgaccgtt caatgattga
     4621 gaaagaaggt cttgatgata caacaatgat tattgtgacc aatacttcgg attattcaga
     4681 agtaaatata gtagctgaaa atacagtcac tgagggtact gatttacttg aaatcaaata
     4741 aatatatttc cctgagtaaa gatggaattt tctttccaaa atcaaataat atagattaat
     4801 caaatatttg agaataacat tttatttaat cttttcatat atcaattgta tgaaaaatta
     4861 ttagaatttt aaaaaatgat aaaaattcaa aaagaaaaaa tagtagttat ttacttgtca
     4921 tgttactaaa taaaaaaata atttaaatat gatatatagt catttattta gtgatttcat
     4981 tctaaaataa agggagaaat gtctatgcta tacggtgcaa ttgaagcagg cggcacaaaa
     5041 tttgtgtgtg ccattggcga tgaagaaatg acgatcaagg aaagagtgag ctttccgaca
     5101 acgacacctg aggaaacaat gcctttagtc attgacttct tcaaacaata ccaagcagat
     5161 ttagcaggga ttgggattgg ctcatttggg cctatcgata tccatcgcga ttccgccact
     5221 tatgggtaca ttacctcgac cccgaaattg gcatggcaaa attttgattt catcggtacc
     5281 atgaaaaaag aatttccgat cccgatttct tggacaacag atgtcaatgc ggctgcctat
     5341 ggtgagtatg tcttcggcag tggcaaagga ttgagcagtg tcgtttacta tacgatcggt
     5401 acgggtgttg gcggcggtgc cttacaagaa gggcgcttta tcgaagggtt tagtcatcca
     5461 gaaatggggc atatgctcgt cgtccctcat ccaaaagatg actttgctgg cagctgtcca
     5521 tttcatggca actgtttaga agggatggcc gctggacccg ccatcgaaaa ccgcttaggg
     5581 aaaaaaggac aagaggttgc agaagatgat ccttattggg aaatcgaagc ctcctatatt
     5641 gctcaatgtg cctacaatac aaccttgatg ttttctccag atgtgatcat ttttggcggt
     5701 ggtgtgatga aacaacgcca tatgctgcaa aacgtccacg acgcatttgc aaaattggtc
     5761 aatgggtatg tcgaaacacc tgagttaagc aaatatatcg tgaccccagc attagaagac
     5821 aacgctggaa cgctcggttg tttggcattg gctcgagaag cggtcttaca ttcataaacg
     5881 aaaaaaggct cttcgacatt tagtgttggt agagaaagat acaactgaaa atttagtcat
     5941 aaccagttag gcagagtgct taactggttt ttgttttact tggaagatca agccttgaat
     6001 gagataaatt cttgctcgaa agttatggaa atttcgatag ccgtaggcca cttgtattgt
     6061 gcaatagttt tttacaaaaa aaagggggtg cggatatttt tttggacctt tttaacaaat
     6121 aggttctgtt gcaaagtttt aaatctacta tcagataagg tagaataata gaaaaagata
     6181 gcaggaggaa tgacgatgag tcattttaaa ggaaagcaat ttca
//
LOCUS       DADQDV010000120         6053 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.124, whole genome shotgun sequence.
ACCESSION   DADQDV010000120 DADQDV010000000
VERSION     DADQDV010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6053)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6053)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6053
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.124"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(196..483)
                     /locus_tag="J8S10_002838"
     CDS             complement(196..483)
                     /locus_tag="J8S10_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HAZ9631376.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(503..727)
                     /locus_tag="J8S10_002839"
     CDS             complement(503..727)
                     /locus_tag="J8S10_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin hiracin-JM79"
                     /protein_id="HAZ9631377.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            complement(1367..1900)
                     /locus_tag="J8S10_002840"
     CDS             complement(1367..1900)
                     /locus_tag="J8S10_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HAZ9631378.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(1921..2865)
                     /locus_tag="J8S10_002841"
     CDS             complement(1921..2865)
                     /locus_tag="J8S10_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HAZ9631379.1"
                     /translation="MANEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMREKGDKTVR
                     FTFDQLKDLSNYKATANVRFVEDLKATYEKILSLRFGRRSESGLSYDMFVMFTEFKIN
                     GDVENPYVDIRIYEKALPLLNNLDEWVRYSLQQFNELQSGYAKTMFRLLKQYRTKGFA
                     YFSKEDFLELLDIPKSYKQPDIDKRVIKPIRQELTAIFKGLTIKKKYGKGRGKPVIGY
                     QFTFKPEIKKADDFNKHAPTKEDQNKALALADKQKEYEEPATTINEKIKQKKRELELL
                     QQIKQLEKEKKALEKQTESALSEKEKKSLLSDLDNLFQ"
     gene            3502..3588
                     /locus_tag="J8S10_002842"
     CDS             3502..3588
                     /locus_tag="J8S10_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011302749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HAZ9631380.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(3709..4398)
                     /locus_tag="J8S10_002843"
     CDS             complement(3709..4398)
                     /locus_tag="J8S10_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631381.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(4405..4683)
                     /locus_tag="J8S10_002844"
     CDS             complement(4405..4683)
                     /locus_tag="J8S10_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631382.1"
                     /translation="MKEEQTTNKNYRSKTLQDIENEIKKQRAFLAPYTKERIQTTIDS
                     QVKKFHHALLNQRNKEQKKVIMQRSMDILAPLCCLIMTLLAFWLVWGE"
     gene            complement(4643..5557)
                     /locus_tag="J8S10_002845"
     CDS             complement(4643..5557)
                     /locus_tag="J8S10_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HAZ9631383.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            complement(5539..5919)
                     /locus_tag="J8S10_002846"
     CDS             complement(5539..5919)
                     /locus_tag="J8S10_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HAZ9631384.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
BASE COUNT         1599 a         1113 c         1022 g         2319 t
ORIGIN      
        1 tcgcttgttt caccttcggt gaaattgttg caaatcaata attaggtaga gctacatttt
       61 tttcgttgtt caaagattct tatgccattt actattaata aatctataaa tatgataatt
      121 tttcggctct ataatttatg ggactgatga atcagaattg attcttcagt cccattttca
      181 ttttattcca aagaattaac tccaaatacc aatagaagcc catcctctat atacttgaga
      241 ttccttacta acaatttctt gtaattctat taaagattta ggtaatccaa atttatgttt
      301 taaaatatat cttccaagaa aactacttaa tttcatacta acttcaccaa cactttttcc
      361 ctcactgatt tctttagaat aaagaaagag cttttctttt aagtcaggat agtcatctat
      421 agttgcttca ttgtatactt tactaattgc atttaaaagt ttttcttctt tagtaaaatc
      481 cattataata acctccctac cactaccttc taggtgccca tggaccatga ttaacccaac
      541 cattaacaat aatttttcca atttctcctt tagcttgatt ccaatctacc caacattttt
      601 ctttgttaca ataaagacca tttccatagt aagtagctgc atcaactttt attcctgtac
      661 cgatgccagc tagacaagtt cctaatattc ctagaataac acaatgtttt aatactttct
      721 ttttcatgat tgtttttcct tttcgttttt ttaaaattgc ttgttatatt aaataatctt
      781 agtaatttta ttatataaca ttttattata taacaatgat taacgtcata aaaagtagtt
      841 ttgaattcat aatcgtttaa ataaaattat aagatcagtt atttaaacag ctagtagaca
      901 taatgtcgat actaccaagt aacgcctgta ccaagggatc caggcgctga ttttgtgaat
      961 ttttattggt ctaggttaaa agctcttttt aaggcttggt tttctgcggt tgtttctttc
     1021 taattctttg tgaatattga tcggtcattt tttaaatact tgttattttt gtttgtgttt
     1081 gttatgcttt ttacatatct catattcatt tattattctt ttctaaggtt aataatagga
     1141 taatctcttt cagaaagact gctcgtacga gcagtctttt cttatttatc aagtttttct
     1201 acaaatactt cctcattttg actgttgtag taattaggat tgagttttag ttcccctttt
     1261 ttatttcctt tgttggccac tgataataac attgggctaa agcttaatat tcctagtagg
     1321 atagaaccga atagcaagtg tttttttgtc ataagtattt ccttcttcat ttccatagct
     1381 gccaccattt tttccaattc tttgtttgtt cgtccattgt ttctgttgct tcagaaagag
     1441 tcgttgaact attctctgaa gactcttccg tataagtcaa ctgcagttgc tcctgaagtt
     1501 tttcgatttg ttggttggct tgcagggtga gttgttgttg ctggtcgagt agtttttgta
     1561 tatgagaatt attttgctct ttgagggcaa gttgttctcg taaaaattca ttttcttcac
     1621 gcaactgatc tagcaacttg tttgcaacca cgtttttgtt tggtatataa gcatttttat
     1681 cgttgttttg ttcatgttta tgcaacttat ctagcaacct ttgattgtct aagttgcgag
     1741 caagttgcaa tactccagaa cgcaatacaa ccttataacc acgctcattt ttagctatca
     1801 tggaagaatc taatttttgg atatgtttcg atattgcttg cctactcatc ttaaaaagat
     1861 ctgacaattc ctttattgta aaggtttctt gtggttgcat actggttgcc tcctaggttg
     1921 ctactggaat aaattatcta aatcagataa taaacttttt ttctcttttt ccgaaagtgc
     1981 ggactctgtt tgtttttcaa gagctttttt ctctttttct agttgtttga tttgttggag
     2041 gagttcaagt tctcgtttct tctgtttgat tttttcgtta attgttgtag cgggttcttc
     2101 gtattctttt tgtttatcag ctaaagccaa tgctttattt tggtcttctt tggttggtgc
     2161 atgtttgtta aagtcgtctg cttttttgat ctcaggtttg aacgtaaatt gatagccaat
     2221 aacaggtttt ccccgtcctt ttccgtattt ctttttgatt gttagtcctt tgaagattgc
     2281 agttagttct tgacgtatag gttttataac tcgtttatct atatcaggtt gcttataact
     2341 tttaggaata tctaataatt caagaaagtc ttctttggag aaatatgcga aacctttggt
     2401 tctgtattgc tttaacagac gaaacatagt ctttgcatag ccactttgta gctcgttgaa
     2461 ttgttgtaaa gaatagcgta cccactcgtc taaattattt aacaaaggca gtgctttttc
     2521 gtaaattcgt atatctacgt aaggattttc tacgtccccg ttgattttaa attctgtaaa
     2581 cattacaaac atatcgtaag aaagcccaga ctcacttcta cgaccaaagc gtaaagataa
     2641 gattttttca taagttgctt ttaaatcttc tacaaatcgt acatttgcag ttgctttgta
     2701 gttacttaaa tcttttagtt ggtcaaacgt aaaacgaact gtcttatccc ctttttcacg
     2761 cattctagac acgatggaaa aaaacaaatt catttcaacc ggtgtaaatt ttcttaaagg
     2821 aattgtattt aattcatggt ggtattttac aatctcatta gccatataat cacctcaatc
     2881 caattatgaa tgacattttt taaatgtcaa gacattcata tttgacgttc aaacagacaa
     2941 aatgtccttc ataaacagac aaaatgtcct tcataaacag acaaaatgtc cttcataaac
     3001 agacaaaatg tccttcataa cattctgtat ccattggtag agtaaggaca cagcttacgg
     3061 taaagaggtt taaaaagagg tttaaaaaga gatataaaaa gaggggggct aattttcccg
     3121 cctaaaaacc acttcttttt tctttaaaca ggttcgcgca tttttcaaaa ctgccaatcc
     3181 aaaaccttgc ttcctacggt cgccaaaaag gtgtgatcgc tacgctctca cattgtactg
     3241 cgcagtcgcc taaaggctcc tttgctaaaa acatgttggt aaagaggcct ttgagcggtt
     3301 ctgaatgctt atctaagccg ttttaagaca gtcttggata aaaatcctta tctagcttta
     3361 aagcgcctta caggcggtca gggcaagccc taacaaccct aaaataagcg atacttaaaa
     3421 acaccacaca agtttaattt tttaagatat aataacttgt cgcctatccg acagtcttgc
     3481 gactggaagg aggtgtatct aatgtttgaa ttgttcattt gcccccttct tatagaagtt
     3541 tgtgtctctt tattcagtta ttggttgaat aaccgaaaca agaagtaaaa tcaataaagg
     3601 cgacatcaac ctgaaaaaaa gccccagaga atccaacctc tctggggctt tcgtgtatct
     3661 aatgtttgat catttgcatg tttagtttaa catgattgcc gatcaaattc aattttgctg
     3721 ttgctgatct aaccattcct tgacactttt tagataattt aatgccgttt cttttttcgt
     3781 tggattttgt atgttcgttg cttgctgaag cagtgcttta taacgttcgt aggtaactga
     3841 ttgttgccgt tcttttcgtt cctgttcact agttgaaaaa gggattgtat cactgaataa
     3901 attataacaa gcttcttctg tctgcgtatc tttaaaatat tgcacgtctt ttttggttcg
     3961 ctcatagttg tcttgaacct ctttttgctg tttttctggc aagttttgat aaagacgagt
     4021 gagtttttcc atgtttttat ccgtcaaacg tttttcttga ttcacaaaaa tatcgttcat
     4081 ttcctcataa caagtggtaa actcttccat tttttgtgtt aacacttgct cctttttctt
     4141 tttatcacat gctgcttcat acttttgagt gatatcccct aataaaatac ttcttgaaat
     4201 acgtttattt ccctctaaaa cgccgaataa accacttaaa acgattgata atgtaaatat
     4261 aacccctggc aataaaaacc tcttaaatcg aattttagag ccttttaatg aatatcttgt
     4321 ttgataagcc ttatagctaa gccaaataat tcctaaaata ctggcaaaaa tgagtagata
     4381 gggtaaatag aatgccattt ctatttattc tccccatacc agccaaaagg ctaacagtgt
     4441 catgattaag caacataagg gggcaagaat atccattgat cgctgcataa ttactttttt
     4501 ctgttcttta tttcgctggt ttaatagcgc atggtggaat tttttgactt gtgaatcaat
     4561 tgtagtttgt attctttctt tggtataagg tgcaagaaaa gcacgttgtt tctttatttc
     4621 attttctatg tcttgtaacg ttttagaacg ataattcttg ttggtagtct gctcctcttt
     4681 caacgtgttg gtcatggttt cttcgagtcg gtctaatttc cggttgttca gtcgtaagag
     4741 ttcgttgttc tcttcgtact tcttttgcag tttcgcgaat gctagctcga gctcttcgta
     4801 gctcgttggt tcgttgttga ttgtaggctc gttctcgtct gtccagctca tgtaaaatcg
     4861 tctccttttc gtaatccttt cctagtttgt tggatcgtac ttttttcttt ttgtggatca
     4921 attcgtaagt aaaatttttc ccacgattca agcaatgaat gccgaatgtt ttaagagaat
     4981 cacaaaattg gttatacgtt cgagtttttt tgtttttcat tgtttgatca atcgcaaacc
     5041 gaatttcgtc tttccaaaca ggttcatttt tttcttttaa tttgatttca gacatggttc
     5101 gtttttcggg tttcttccct cgttcagtga ttgttaagtc atgttcaaga caaatctcgt
     5161 catttaggtc ataacatttg tttaaaaatg cttgaccatg ggcttgaaat ttgttcccag
     5221 tttccagatt gacggagtta atgacaatgt ggttatgaat atggtctttg tctgtatgtg
     5281 tgtaaatcgc gatttggtgg tcaggggcta tttttttcgc atactctgcc cctagttgat
     5341 tggctttttc agcggtaatt tctcctggtc gaaaagactg gatcaataag tgtgcttgta
     5401 cacgatcgtc ttttccatac agcatgcgaa tttgtttcat ttcgcttttg gcataatcaa
     5461 tgtcacagtt tatccctgtt ttgacggttg ctcgtggttc ggcgtaattg atcgctcggc
     5521 tacaagaagt ggttcggctt actttaactg ttgccatatc ttttgtagct ccttttgcat
     5581 gatttttagg ttttcggata agcgttgggc gtcgccagga tcaacgtcgt gttggtgtgt
     5641 gttgcaccac ttggcaattt gattgatatt cccgccagct ttggctaaat cgcgcgcgat
     5701 tgcctgagca atgtctggcg ccactttcgg tgtcaccaga cgcgcgtttt gtgccttggc
     5761 tttcacgaaa gccggcacac tcatttgcaa agcttcagct gactgcttca gctttgcaaa
     5821 ttcggattcg ctcactcgaa aactgatttg ttttggctcg gatcgatagg tatatttttt
     5881 agaatgattg ctagccaaat attgattttg ttcgctcata agtcccaccc tttcagtacg
     5941 tcctacggac gtatcgttcg caataccatt gtacctaaaa aggtacaata agtaaagctc
     6001 actaaagctt actaaagggc ttggcaagct ctatatttgc tagccaaata cct
//
LOCUS       DADQDV010000121         6020 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.125, whole genome shotgun sequence.
ACCESSION   DADQDV010000121 DADQDV010000000
VERSION     DADQDV010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6020)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6020)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6020
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.125"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(60..362)
                     /locus_tag="J8S10_002847"
     CDS             complement(60..362)
                     /locus_tag="J8S10_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631385.1"
                     /translation="MLMEGKTQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINL
                     YYSNKNYFKIPATKTRMKKDVYFLFDIVTDVPDARSDHRRYDYLKYTFVDPERYKD"
     gene            complement(582..948)
                     /gene="ssrA"
                     /locus_tag="J8S10_002848"
     tmRNA           complement(582..948)
                     /gene="ssrA"
                     /locus_tag="J8S10_002848"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(1119..1892)
                     /locus_tag="J8S10_002849"
     CDS             complement(1119..1892)
                     /locus_tag="J8S10_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAZ9631386.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMGNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            2036..2386
                     /locus_tag="J8S10_002850"
     CDS             2036..2386
                     /locus_tag="J8S10_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HAZ9631387.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            2367..3083
                     /locus_tag="J8S10_002851"
     CDS             2367..3083
                     /locus_tag="J8S10_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAZ9631388.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAVVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            3083..4531
                     /locus_tag="J8S10_002852"
     CDS             3083..4531
                     /locus_tag="J8S10_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAZ9631389.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(4602..5111)
                     /locus_tag="J8S10_002853"
     CDS             complement(4602..5111)
                     /locus_tag="J8S10_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631390.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(5151..5825)
                     /locus_tag="J8S10_002854"
                     /pseudo
     CDS             complement(5151..5825)
                     /locus_tag="J8S10_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876864.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         2045 a         1050 c         1170 g         1755 t
ORIGIN      
        1 cccttttata agtatggtga taaaatccgt tccgggctac cttttttagg tagcctactt
       61 taatctttat acctttctgg atcaacgaaa gtatacttca aatagtcata acgccgatga
      121 tcgctccgtg cgtctggcac atcagtcacg atatcaaaca aaaaatacac atctttcttc
      181 attctggttt ttgttgccgg aattttaaag tagttcttat tagagtaata gagattgatt
      241 aataagctat cttcgattgc taaaaagaaa acttctgaat cccacacctt ataaaaatct
      301 ttgacaaatc tattcgaagg atcaaattta aaccataatt gtgtttttcc ttccatcaac
      361 ataatgttca cctcaaaaag agtatacgaa ctaatgttct ttttgtaaag taggaatatc
      421 attgataata tggatggaac atatatatta aaaagtgttc tttttgaatg ctattttgaa
      481 tgccattttc attcatttaa cgaaaatctg cgaaaataaa aaatgctcaa acccttataa
      541 aataaggatt taagcatcta gcgaaatctg ctgaaatctc acaatggaga cggcgggagt
      601 cgaacccgcg tccaaacaca tcgccactta aaaatctacg ttcatagtca actcatttaa
      661 ggattcactt tacagcttgc cgagtgacag gcattctgta tcgctagtct gatgttctct
      721 ttttcaactt acagacggaa agttgaaacg tatcccacta aagttaggac ccttactcga
      781 gcacatgggc gatgccgaga ggatctacgc taactgtttt taggcagcta aagcgtaaga
      841 gttgttttcg tttttagcag ttatatttaa ctgtaacgtt tttacgtaga cgtaacctac
      901 gaaacgcaat tcaagctcga ctgtgcctgt cgaatccgta acgtccccgt tagctaacaa
      961 gggttacgtg tatttttcat acaaaattag tatagcatat attgggataa attcaataaa
     1021 aaagcgaatc atatcccatt atttatataa taactgcccc tttcttaaga aaaaataagc
     1081 gattttctta agaaaagagg tagcttcaaa aaaagatctt aaatcagatc aaaatacttc
     1141 aatgcgtgga caattccgcc ttctgtattt ttctttgtga taaaggtaga aagttctttt
     1201 aatccgtcat aggcgttgcc catagcgatt ttgttgtcgc aagcttccaa caaggcaaaa
     1261 tcattcggac catcgccaaa tccaaaagta ggaacttttt ccagctgaag ttctttttgc
     1321 agacgtttga cacctgcccc ttttgagatt cctttcttca ctgtatcgat cgagtaagga
     1381 ccattccgat aaaaagttag ctcaggaaaa tgttcgtgat agtattcgtc acctgattga
     1441 gataagatca gcaacatatt tactgtgttt tctttaaagc ctaaaggatc aatttccgga
     1501 acatctgaat gaatgaagtc gtaagcattg atcattgttt ggctatgacc ggtacaccag
     1561 attttctgat cgttatagta agaaagttca tgaccgttca actgtacatg atcatacatt
     1621 ttttgacatt cttctgaaga aaatgtttga gaatagattt cttcgccgtc tactcgaatg
     1681 aaagaaccat tcatggtgac cgcagaagta atgcccgcat cttccatgat agagtggatt
     1741 tctgcttctg tacgtcctgt agcgatgacg gggagaacat tgttttcttt taatgcgttc
     1801 atagcttttg ccacttcggg tgtgattttt gatttcgcat ctagtaatgt tccatcaaga
     1861 tcaaagaaag tgattgcacg ataatttgac acaaataaaa ctcctttttt attggaataa
     1921 gtttatctta acaaagaatg aacaaaagac aaacctttcg tgaagaattc ctgaacatat
     1981 tggttcagtc aacaatttag agtatactat aagaagagaa tttaggaggg aaagaatgat
     2041 ttttttcagt attggtatct tattcttaat aattggcagt ctttttcgga ttctgccctc
     2101 aaaaggaaat ctgccttttt atgggtatca ttcgcctctt gccgcaaaaa cagacgctca
     2161 ttggcggctg gctcaaaaga caagcggaaa ctggtttttt cttatgggct tactgatggc
     2221 attgatcggc tattatttaa agacatctgg gcatacgaat tattttctga ttgaaatgct
     2281 tctgctagta tttccaatta tgcctatttt tattatgaca gaaaagaaat tacagaaata
     2341 tgacctggaa actggaggga acgataatga atattttaat gattgaagat aatcaatctg
     2401 tttctgaaat gatgcagatg tttttcttaa atgaaggttg ggaagcaact ttcaagtatg
     2461 atggaaaaga agggctcgat gcctttttag aaaacccaca acattgggat atgattacac
     2521 tagacctgaa tttgcccaca ctggacggta tgctagtagg aagagagatc cgcaaagttt
     2581 caagtactgt gccgattatc atgctgacag ctagagattc tgaaagcgat caggtgatcg
     2641 gcttagagat gggggcagat gattatgtca caaaaccttt cagtcctctg acgcttattg
     2701 ctcgaatgaa agctttgcat cgccgtagtg agttggcaga agcaagagaa gaagcagtag
     2761 tttcagatga tcattttgat atcgagacta gtcatttcaa gatgaatacg aaaacacgag
     2821 aagcgtatct ggacaaccgg ccaattgaag gactgacgcc taaagagttc gatctattgt
     2881 ttactttagc aaaaaaacca cgtcaagtat tctctcggga gcagttgctt gaattagtct
     2941 gggattatca gtactttggt gatgaacgga cagtggacgc ccatatcaag aaattacgac
     3001 aaaaaatcga aaaggtcgga ccacaagtca tccaaactgt ttggggagtc ggctacaaat
     3061 tcgatgattc tggtgttgcc taatgcgtta tttgtatcag caactcttag ctttctgcgg
     3121 aatggtcgcg ttgatcttat tgatcgttgg agtttctttt acacaactga caaaacaaac
     3181 gattgaagaa aacaattacc agcaactgtt tggatatgct gaatcagttg aaaagacaac
     3241 gcaaacctat gccgatacgc tcccgcagtt tagtcaagat caggcgtttc aaaatgcatt
     3301 gctgctgaca gagcaagtac tgacagaaca aaatgtgaac tttatattta tcgataaaaa
     3361 cgaacgtgtc atttatccga ctaatacagc tttactgaat tttaccttaa cagctgatca
     3421 atggaaaaat ctgaggaatg gacgtcaaga aaaattcaca tcgaataaaa atattttagg
     3481 acaagcacag gcgacctctt acgcacttgt gccatttaat ttgaatcatg aattctatgg
     3541 agcacttgta gttagtcaac ctgcgcgaaa tatcgataac agcgttcgtc caattacact
     3601 gaacctgttc aaaggattta ttttttccag tatcgttgca gttattgcca gctatgcttt
     3661 tgcagcattc caagttaagc gtatcaatcg gttaaggaat gcgacgaaag aagtgacgaa
     3721 tggtaatttt gatgtacagc tccccgtaca tgacaaagat gaatttgatg agttagcaga
     3781 tgatttcaat aaaatgacga attcattgaa agaatctcaa gcagaaattg aagaacaaga
     3841 aaatcgtcga agacaattta tggcagatgc ttctcacgag atgagaacac ctcttacgac
     3901 aatcaacgga cttctggaag ggttagaata caatgcaatc cctgaaaatc agcgagaaaa
     3961 cgcgattaaa ttgatgaaaa atgaaacaga gcgtctgatc cgtttggtga atgaaaactt
     4021 ggattatgaa aaaatccgta cgaatcaaat cagtatggtc attaaaaaat tcaatggaac
     4081 agaaacattg aaaaatattg ttgcacagtt agaagctaaa gcagaagcag caggagatac
     4141 attgacattg aaagccgttg atgatattga tgtttacgct gattatgacc gatttgtcca
     4201 aatcatggtc aatattattc aaaacgcgat acagtttact gaaaacggcc aaatcacgat
     4261 tactttagaa aaaggctatc ttgaaacgat catcacgatt gaagatacgg gaattggaat
     4321 gtctgaacaa caaatgaaaa gtatctggga tcgttattat aaagtagatc cttcaagaaa
     4381 aaatacaaaa tatggtgaat caggattagg tttaccaatc gtgcagcaac ttgtacgctt
     4441 gcataaagga aaattagaag tagaaagcga actaggaaaa ggaacaaaat tcgctgttcg
     4501 tttgcctgac gtagaaatca aaaaagagta aaaaacaagc ggtataaaag atcatgaatc
     4561 gatcttctat accgcttgtt ttttactata aaatgattga tttagcccgc gggctctaaa
     4621 cgatcaatat aaggactttg agcaatagta gcatcatgag taaagagtaa gataccttga
     4681 ttttcttcat gagctaaata agaaagcaag tggagtagct cttggatctc caatacacta
     4741 agttcatcaa atgtatcttc aataacaata ttgtttcgct tggaaagcaa ggcatgaagt
     4801 aattgcagct ttactttttc aaaagacgtc aactcagctg ccgcacaatt aagcaaggaa
     4861 ggagagatat caagtttttc ttgataggcc aaacgatctt gtttgatttc tttttccggt
     4921 acatccaaca ggacatggtc tttaagattc agataaggaa acatcggcca atttttttgg
     4981 atgatcgcaa aattatccag ttttgcaaca agaacctctt ttttcaagtg ctccaatatt
     5041 ttatgctgtt tttcgagagg acacaaaata acggtcaagt gttcagcatg aatcaaatat
     5101 tcaggtttca ttacgtccag gcctcctact ttgcaaatga tggataaaaa agtgaaaggg
     5161 aatagactaa gaatgagaca gcatccactg agcccaataa gagtttgggc aaatccctta
     5221 agtatatctg tgaaaaaaag atcattttgg aaatcgatgg taaaaaaagt ctgttgatcc
     5281 atcggaattg taagtccgct taccgaagtc aagatatcac ggatatctgg cagttcagta
     5341 gtctttaaga caagaaaatt gatcctttga agaagcgctt cataaactga ctggaagctt
     5401 acgatccaca ataaaaccaa gatacaacaa agaaagagag gaaagaacag ctgccagaaa
     5461 ataaaaagga ataatttggt tttagaaaga ccagtcaggt gccaattgat caattcctgc
     5521 ttgttttgcc tgactgaata gtaaaagaaa aagataaaaa ggaaggcaaa tagaaaaaat
     5581 aaactgaata tgccttttat ataaaatcgg ctagctaatt ctaaagccgg aagaagctct
     5641 gtagatgcag aagcgccaat aaatgaaagc cgatcttgga cttgattggc taaagccgat
     5701 tgcaaatggt aaagagtcag gcatgctatc aataaaaaag cagaaaagct tgaaaataaa
     5761 caatagagta ttgtctgctt tttgtaataa attaatcgag cagtagcata gcggattatt
     5821 ttcatacttt tcacctctat aaaaagtata gaaaatgaat atgaataaag tatgaaattc
     5881 ctttagtgaa atcacgaatt aaaaccagaa aatattttgt aaaaagcaag aggttgtgaa
     5941 gaagctgccc tattctatta ccgtagatgc aagcttttga acactgttta ttcgaaaaga
     6001 ggagcagcga caataatttt
//
LOCUS       DADQDV010000122         5999 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.126, whole genome shotgun sequence.
ACCESSION   DADQDV010000122 DADQDV010000000
VERSION     DADQDV010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5999
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.126"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..203)
                     /locus_tag="J8S10_002855"
     CDS             complement(<1..203)
                     /locus_tag="J8S10_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HAZ9631391.1"
                     /translation="MSEGTKRNDNKLFNSLYKITVNDVVEKRNKLTYLSWAWAWAEVS
                     KICDEVDYEIYRDPETNRPYLFD"
     gene            complement(196..537)
                     /locus_tag="J8S10_002856"
     CDS             complement(196..537)
                     /locus_tag="J8S10_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631392.1"
                     /translation="MKKELSTLDQYLTDPSWGKSNIKETNNRKIRRNLLTDEELACDQ
                     DDLGNFVSIWGHVYLIHLWKQPRKPEYIYVIEDGLIDALEEYDRDNLIDISYYGSGKK
                     YIAEMEAEFDE"
     gene            complement(716..1414)
                     /locus_tag="J8S10_002857"
     CDS             complement(716..1414)
                     /locus_tag="J8S10_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HAZ9631393.1"
                     /translation="MQELVILKNKEAVTTSLQVADSFEKEHKNVLRDIEKLKEDVLNF
                     EQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMEVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDENE"
     gene            1468..1929
                     /locus_tag="J8S10_002858"
     CDS             1468..1929
                     /locus_tag="J8S10_002858"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631394.1"
                     /translation="MKKLLYILLFSTFAIVALLLLFEHLKRVNLDGTLLEEQIAILNT
                     PKLLIVFFFMCMLSALIFMFYISTFWVYKEIKNKEFTDKDMIFMGFLVKILFIFSIVI
                     TLLFCLNETQFSVATTLISFIAIFSFIFSDNQKKSINGFLQKIKKKINGEP"
     gene            complement(2127..2378)
                     /locus_tag="J8S10_002859"
     CDS             complement(2127..2378)
                     /locus_tag="J8S10_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAZ9631395.1"
                     /translation="MEQLALVNLSALKASLAESEIANEVWDTKQAAEYLKTTTRTLTK
                     DAESGKIPAAKVGREWRFSSIALYQYLKGGKTWANSTEH"
     gene            complement(2392..2583)
                     /locus_tag="J8S10_002860"
     CDS             complement(2392..2583)
                     /locus_tag="J8S10_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631396.1"
                     /translation="MSNLDNGRAAIKKFMRENGVTMEDLATAYGYTRVRMQQIIDGHW
                     SGPKANKTILEIIRDYRIR"
     gene            2876..3196
                     /locus_tag="J8S10_002861"
     CDS             2876..3196
                     /locus_tag="J8S10_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAZ9631397.1"
                     /translation="MTLFERIKSLASQRDKSMKEVALELGFSENLFYRWKTTEPKARD
                     LQKVADYFNVSVDYLLGREEKETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            3214..3636
                     /locus_tag="J8S10_002862"
     CDS             3214..3636
                     /locus_tag="J8S10_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HAZ9631398.1"
                     /translation="MYLKLKEMLSEYNLKLIYMEMEEPGFYYPKPRIVFLNEKLHEDS
                     SEAFHLAHELGHFIASHFEYSVLYDNSTTFHSKFEAEADRIAIMILLNIFIENELTDE
                     SQFKLENFMEFYSINNKLRTECFNVCQSYFKKKYSYAQ"
     gene            3719..4354
                     /locus_tag="J8S10_002863"
     CDS             3719..4354
                     /locus_tag="J8S10_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HAZ9631399.1"
                     /translation="MAKKVMGQDGKMYKVKKPFYKRVWFWVLIVLLFFGIGGALSGGE
                     NKDSATATSTSTNKETTKETTTKEEKTYKIGDDVAVGKMEYKVNSVEVVKQVGPSVLP
                     TNAKDTFLVVDLSVKNAGDKAVTVDSSFFKLKADGKTFEADSAASMSANQDENGNITN
                     SFFMESLNPDMQQTGKIVFDISEAQANAQNNVLQAQTGYFGTETVSIALHN"
     gene            4472..5683
                     /locus_tag="J8S10_002864"
     CDS             4472..5683
                     /locus_tag="J8S10_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAZ9631400.1"
                     /translation="MSEVTGYLEQVDNETYRLRAVLGYKPDGSAKRKSKTIKANSKRA
                     AYKELNIWLEQFEGMTDDSLDLFNITFGEFYRKIWLSEAEKNLEPKSYHNYKRMIENR
                     FLDKFDFIPLIDIKPYMIKKIVVNAQRINTKDPGRNSDKPLSRNTKLRMLYAVNNLFL
                     MAKNEYGAIKENPVENVKIPKEKGVKKNIEEPYSEEEIHAMLKAAFEESIEIKTLIVL
                     AFITGARQGEIAALEEKDIDFDKQEIRFHQRISEVDGKSDIRLLPGLKNDDDEKIVTG
                     PAYLFDMLDELIKENKKIRWKLNIKKLRHYFIFDTKQDGTLPRGSYLYKKFKRFTKRH
                     NLRHIRFHDIRHTSATYLLSDPNMTPKELQKRLGHRDFNTTMNVYGHVLRKEKDTATT
                     AFEKLLKKDIK"
BASE COUNT         2021 a         1031 c          993 g         1954 t
ORIGIN      
        1 tcatcaaaga ggtatggacg atttgtttct ggatcacgat agatttcgta gtctacttca
       61 tcgcagattt tgctgacttc tgcccacgcc catgcccagg acagataagt tagtttgttt
      121 cttttttcga caacatcatt gacggttatc ttgtacagac tattgaataa tttgttatcg
      181 ttgcgtttcg ttccttcact catcaaattc tgcctccatt tcagcaatgt atttcttacc
      241 tgatccgtaa taagagatat caatcaagtt atctctgtcg tactcttcta gtgcatcaat
      301 caagccatct tcgatgacat agatgtattc aggttttctt ggctgcttcc atagatggat
      361 aaggtagaca tgtccccaaa tactcacaaa attgcccaaa tcgtcttgat cacatgctag
      421 ttcttcatct gtcaaaagat ttcgtctgat ttttcggttg tttgtttcct tgatattcga
      481 tttgccccaa ctaggatcag tcaaatattg atctagagtg gaaagttctt ttttcatgtg
      541 gtaacatctc cttagatgta ttttctttgt gactcattgc tttggtcggc tgagtcactt
      601 ttttatttgt tgccatgctt tttgcttatc aatatgttgc ttgcttaaaa taataggacg
      661 gctatttgcc caccaattat cagccatcac tttaccgatt tttagagctt cagctctatt
      721 cattttcatc accgaaaagt ctttgttgtc tgttcagttg atcgatttcc atgcggatcg
      781 cagtttctgg taaccacatt tcaataaatg aaacagcatc atcgaatctc ttacgaggta
      841 actcgccata tcttgggatt gaaaaggtac gtttaaattc agaccaaaat tttgagaata
      901 cttttttgct gatttcttca taagctcggc tttctttacc tcctaaaact tccataactt
      961 tcatatttcc tttttgctta atttcaaact cttgttgtcc gctaattcgc atagtatctt
     1021 taagcatgga gacatctttt ttaacatctt tcatttcttc tagttggtag atcatcatat
     1081 cttcaattgt ttgaggaaca gtatttttcc gaataacatc ttccatttcg ttgaatgctt
     1141 caatgtactt ctgtttgaag taaatagctt tctttcctgt aaatcccata gccaacaaga
     1201 aaaatccatc tctgctaatg aagaaaactc gccgatttct accgtatgaa tctggttcat
     1261 taccttccac aaacatctgc tcaaaattga gcacatcttc ttttaacttt tcaatatctc
     1321 tcaaaacatt tttgtgttct ttttcaaaac tatctgcaac ttgcaaactc gtagtcacag
     1381 cttctttatt tttcaaaatt actaattctt gcattttttc ttctctcctt ttgatataat
     1441 ttaggtaaaa aatggtggtg gaaatatttg aaaaaattgc tatatatttt acttttttca
     1501 acctttgcaa ttgttgcatt attgttgctt ttcgaacatc ttaaaagagt aaacttggat
     1561 ggaactttgt tagaagagca aattgcgatt ctaaatactc ccaaattact aattgtattc
     1621 ttttttatgt gtatgttatc tgctctgata tttatgttct atatatcaac tttttgggta
     1681 tacaaggaga ttaaaaataa agagtttact gataaagata tgattttcat gggtttttta
     1741 gtcaaaattc tttttatatt ttccatagta atcactttat tattttgttt aaatgaaaca
     1801 caattttctg tagcgaccac tttgatttca tttattgcta ttttttcctt tatattttcc
     1861 gataatcaga aaaaaagtat taacggattt ctgcaaaaaa taaagaaaaa aatcaatgga
     1921 gaaccctaat ataaaaatca ggaaaaaaat attgattact cctcttagga agaccattag
     1981 tcagtccctc ccggctggct ttttcgctct gtactcagct tcatcaagcc ccataaaaat
     2041 ccaaaccatg taaacgatcg ttcctatcaa cgcttgcctg cttccccaaa gccctaaagc
     2101 gtagatgatt agcggtgcgc tgaatactag tgctctgttg aatttgccca tgtttttcct
     2161 ccttttagat actgatacaa agcgatacta ctaaacctcc actctctgcc aactttcgct
     2221 gctggaatct ttccagattc ggcatcttta gttagcgtgc gtgtcgtggt tttcaaatat
     2281 tccgcagctt gctttgtatc ccacacttca tttgcaatct cagattctgc caaagaagct
     2341 ttgagggctg agaggttaac taaagctagt tgttccattg attaattcct cctatcgaat
     2401 tctgtaatca cggatgattt ctaagatagt tttattagct tttggtccac tccaatggcc
     2461 atcaataatt tgctgcattc gaacacgtgt gtatccatat gcagtagcca aatcttccat
     2521 agttactccg ttttctcgca taaacttctt gattgcagca cggccgttat ctagatttga
     2581 catctattca ctccccttac atatagattt gtaagtcaaa atgatagaaa aaacgtataa
     2641 actattgact aatagtatac aatcgtatac tatataaaca tagttaaata agcctacaac
     2701 aaacccttta ttatgcaatc ggtcgccaaa cttaatgcta taaggtgtat ttttagtttg
     2761 ctttttttct atcaaattaa cttacaaaca aataataata caaacttata cttatgtcaa
     2821 cagtataatt tacattttgt gtacttttat ttgtttagga ttggagaaca ttattatgac
     2881 actgtttgaa aggataaaat cattagctag ccaaagagat aaaagcatga aagaagtcgc
     2941 tttagaatta ggatttagcg aaaatctttt ctatcgatgg aaaacaacag aacccaaagc
     3001 aagagatttg caaaaggtag ctgactattt caatgtctct gtagactatc ttctaggtag
     3061 agaagaaaaa gaaacgccta aacatgtgga tttatcagaa gatgatactg tattttcttt
     3121 tgatggaaaa gaaatatcta aggagacaat gcgtaaagcg attgcaattg ctaaagcttt
     3181 agaggaaaat gaatagttgg agtgatgggt tgtatgtatt taaagttgaa agaaatgctg
     3241 agtgagtata atttaaagtt aatctatatg gaaatggaag aaccaggttt ttattatcca
     3301 aaaccaagaa tagtattttt gaatgaaaaa ctacacgaag acagttctga agcttttcat
     3361 ttagcccatg agctcggtca tttcattgct tcacattttg aatattcagt actgtacgat
     3421 aactctacaa cttttcattc aaaattcgaa gctgaagctg atagaatcgc aattatgatt
     3481 ttactaaata tctttattga gaacgaattg actgatgaat ctcagttcaa attagaaaat
     3541 ttcatggaat tctactctat caataataag ttaagaacag aatgttttaa tgtttgccag
     3601 tcatatttca agaaaaaata ctcttatgca cagtaaaaaa agcccgtgct gcaacacgga
     3661 ctcatacctc atttctgaga tcacaaatat attataacaa gaagtgaggg atatttaaat
     3721 ggcaaaaaaa gttatgggtc aagatgggaa aatgtataag gttaaaaaac cgttttataa
     3781 acgggtatgg ttttgggtat taatagtact tttgtttttt ggtattggtg gtgctctaag
     3841 tggcggtgaa aacaaagatt cagctactgc aacatcaaca agtactaata aagaaactac
     3901 aaaagaaact acaacaaaag aagaaaagac ttataaaatc ggtgatgacg ttgctgtagg
     3961 gaaaatggaa tacaaagtaa actccgttga agtagtaaaa caagttggcc catctgtact
     4021 tcctactaac gcaaaagaca ctttcttagt agttgactta tctgtaaaaa atgcaggtga
     4081 taaggctgtg actgttgata gctcattctt caaattaaaa gcagatggaa aaactttcga
     4141 agctgattcg gctgcatcta tgtcggcaaa tcaagatgaa aatggtaata tcactaactc
     4201 tttctttatg gaaagcttaa atcctgatat gcaacaaact ggtaaaatag tttttgatat
     4261 ctctgaagcc caagcaaatg cacaaaataa tgtattgcaa gcacaaacag gttactttgg
     4321 aacagagaca gtttcaattg ctcttcataa ctaattagta taaaaaacac gccccaccga
     4381 ccaaagcgag cgtgttctaa gaaaaaacaa acctacacaa taggcttctt tatagtacct
     4441 attgtatcag agaaagagag ctgattcaat tatgtcagaa gtaacaggat acttagaaca
     4501 agtagacaat gaaacatata gactaagagc tgtattaggg tacaaacctg atggctcggc
     4561 aaaaagaaaa agcaaaacta taaaagcgaa tagtaaaaga gcggcatata aagaattgaa
     4621 catctggtta gagcaattcg aaggaatgac cgatgattcg ttggatttat tcaatataac
     4681 ttttggtgaa ttttatagaa aaatatggct ttcagaggcc gaaaaaaatt tagagccaaa
     4741 gtcttatcat aactataagc gaatgatcga gaatagattt cttgataaat ttgattttat
     4801 ccctctaatc gatataaaac catacatgat aaagaaaatt gttgttaatg ctcaaagaat
     4861 caatacaaaa gatcctggaa gaaactctga taaaccttta tcaagaaata caaagcttcg
     4921 tatgttatac gccgttaaca acttattttt gatggctaaa aatgagtacg gagcaattaa
     4981 agaaaatcct gtggaaaatg taaaaatacc aaaagaaaaa ggcgtaaaaa agaatatcga
     5041 agaaccttat tcggaagaag aaattcatgc aatgctaaaa gcagcatttg aggaaagcat
     5101 agaaattaaa actttaattg ttctagcatt tattacagga gcaagacaag gagaaattgc
     5161 agctttagaa gaaaaagata ttgactttga caaacaagaa ataagatttc atcagcggat
     5221 ttcagaagtg gatggaaaat cagatattcg gttgctgcca ggtttgaaaa atgatgatga
     5281 tgaaaaaata gtaaccggtc ctgcttatct atttgatatg ttagatgaat tgatcaaaga
     5341 gaataaaaaa attcgttgga aattaaatat aaagaaatta agacactatt ttatatttga
     5401 tacaaaacaa gacggaactt taccacgtgg aagttatctg tataagaagt tcaaacgatt
     5461 caccaaacgt cacaatttgc gtcacattcg ttttcacgac attagacata catcagctac
     5521 ctatttgctt agcgatccta atatgactcc aaaagagctt caaaaacgat taggacaccg
     5581 agattttaat actacaatga atgtttatgg ccatgtctta cgcaaagaaa aagatacagc
     5641 aactacagcg tttgaaaaac tattaaaaaa agatataaaa taacactaaa aaattatatt
     5701 ttcgggtata aactcgggta ggatatataa aaacttggga taatttgcgg tatataagca
     5761 tttaaaaatg ctgtaaattc gcttatcttc atttaaaata ccattaaata acgaactctt
     5821 aatcagcggg tcgcgggttc gagcccctca cggcccattg ggtgccaaac ccacggaaca
     5881 ggtaaatgtt ggtgcgaaag catttcgaaa acatttacgc tgttcttttt ttattttcgc
     5941 cgtttgtata attaagcgag acaaataaaa aagccattta tgttacactc aaattgtaa
//
LOCUS       DADQDV010000123         5954 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.127, whole genome shotgun sequence.
ACCESSION   DADQDV010000123 DADQDV010000000
VERSION     DADQDV010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5954)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5954)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5954
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.127"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..813
                     /locus_tag="J8S10_002865"
     CDS             <1..813
                     /locus_tag="J8S10_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HAZ9631401.1"
                     /translation="KKNTNGEYSGSISQFLAKELQNLVDSNITDTTLFFQDNSIYYSD
                     NGQIKLLWKSPLSTEKNGVSSFTEKNDLISVNIKNKIKNFSKKQNFPAVKRVKSVSSG
                     DNFIMINWRIAETQTSFPWCAAYVEAAILCNKTDVRATSARAIMHYTYPNLNNSQIES
                     KSLNQDQIIKYANYCGVYPKKVARILNLSEVQTQLRKGNAIYMGTAGYGNYSNSRHAL
                     ALFGWVNQGGYQTYYVWNPWYNYPTVISANAGPVTIPVPGGGFTWDNTITNW"
     gene            807..1229
                     /locus_tag="J8S10_002866"
     CDS             807..1229
                     /locus_tag="J8S10_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631402.1"
                     /translation="MVNKPIALVMGLVLVLFLTSCSKKQEIQKTDLIPFLGTWQTKDH
                     SERLVITNLNTSKNIEQYTILVKENNHKIQIIDKNLNINEQVFIYKATNNLLTLRSNK
                     KQLDYTFSLDSPKKLVFILTTNDGTEGTAKPIEFFKAD"
     gene            2399..3367
                     /locus_tag="J8S10_002867"
     CDS             2399..3367
                     /locus_tag="J8S10_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HAZ9631403.1"
                     /translation="MSNEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMRDVGDKKVQ
                     FTFEQLKDLSNYKATANVRFIDDLETTYDKLMDLRFGRRSADGLQRERFVLFNQFKID
                     GKSDIPFAEIQVHEKALPLLNNLEEWVRYSLQQFNELESSYSKTMFRLLKQYRTKGFA
                     YFSKEDFHELLDIPKSYNQGTIDQRVFNPIRQELTAIFKGLTIKKKYGKGRGKPVIGY
                     QFTFKPEIKKSDDFNKHAPTKEEQNKALELANQQVQSEKAPTSLQEKIKEQKRKLELL
                     QQLEKLEREQNTQNKENNAQKSEINSDIPSELKKDLLDNLQNLFKD"
     gene            3384..3908
                     /locus_tag="J8S10_002868"
     CDS             3384..3908
                     /locus_tag="J8S10_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HAZ9631404.1"
                     /translation="MTEKTIKELAEELGVSKTAINKKVSDENRKLWFSKIGNKFVINE
                     TGQKAIKSMFFNENENSNQQLVGEKTKTENHKNANQVPELEVLSLLEQQLNQKDMQLQ
                     EKDEQIKQMQKLLDHQQQLTLQANQQIEKLQEQLQLTYTEESSENKSTTLSEETESIE
                     KQSKAEKKWWQFWQ"
     gene            4284..4565
                     /locus_tag="J8S10_002869"
     CDS             4284..4565
                     /locus_tag="J8S10_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631405.1"
                     /translation="MDILVRNINPKIIARIDKRCQELTTKTGKKWSRNKYLKVLIESD
                     FDRQLMNYKKDQFDLLLEKFIAIQTENTNILNDYVHTNNQLIETLIGGI"
     gene            4567..4983
                     /locus_tag="J8S10_002870"
     CDS             4567..4983
                     /locus_tag="J8S10_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631406.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDVNNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIMAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     ENQLNPSRRNQPKNRQKETNQTFTSGNFDPTNFLKR"
     gene            5613..>5954
                     /locus_tag="J8S10_002871"
     CDS             5613..>5954
                     /locus_tag="J8S10_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HAZ9631407.1"
                     /translation="MIILKPKKKIYLGLLFSLMIGIFSIGITNTYASENSNFNINSQP
                     IEEQAINFAKTDFEHSITSILLMENNTETDINYTLGSPFKMLDGENTANSSIFFPVFS
                     DADNTIKYIYTV"
BASE COUNT         2258 a         1018 c          965 g         1713 t
ORIGIN      
        1 aaaaaaaata caaatggaga atattcagga agtatctcac aatttttagc aaaagaactt
       61 caaaatctag tagatagtaa tataacagat acaaccttat tttttcaaga taatagcatt
      121 tattattccg ataatggaca aattaaacta ctttggaaat cacctttaag tacagaaaaa
      181 aatggtgttt cttcctttac agaaaaaaat gatcttatat ccgtaaatat aaaaaataaa
      241 attaaaaatt tctctaaaaa acaaaatttt cctgcggtta aacgtgtaaa aagtgtctcc
      301 tccggagata actttattat gattaattgg cgtatagcag aaacccaaac aagttttccg
      361 tggtgtgctg cttacgtaga agctgctatc ttatgtaaca aaacagatgt acgtgctact
      421 tcagctagag ccattatgca ttatacctat cctaatttaa acaacagtca aattgaatca
      481 aaaagtctta atcaagatca aataataaaa tatgcaaatt actgtggtgt ttatcctaaa
      541 aaagtagcac gaatactaaa cctttcagag gtccaaacac aactaagaaa aggaaatgcc
      601 atttatatgg gaactgctgg ttatggaaat tatagtaaca gccgtcatgc acttgcatta
      661 tttgggtggg tcaatcaagg tggttatcaa acttactatg tgtggaatcc ttggtataac
      721 tacccaactg taataagtgc aaatgcagga ccagttacaa ttcctgtacc tggaggtggt
      781 tttacttggg acaataccat tacaaattgg taaataaacc cattgcttta gttatgggtc
      841 tagtgttagt tcttttctta actagttgtt caaaaaaaca agaaatacaa aagactgatc
      901 tgattccttt tctaggaact tggcaaacta aagatcattc agaacgtcta gtaatcacta
      961 atttaaatac ttcaaaaaat atagaacaat ataccatctt agtaaaagag aacaatcata
     1021 aaattcaaat cattgataaa aatttaaata taaatgaaca agttttcatt tacaaagcaa
     1081 caaataattt actaacactg cgctctaata aaaaacaatt agattacact tttagtttgg
     1141 attctccaaa aaagctcgta tttattttga caacgaatga tgggacagaa gggacagcta
     1201 aaccaattga attttttaaa gctgattgat gaatagttgt ttgatattac aaaacaataa
     1261 tttcaccgaa ggtgaaacaa gcgaaacttt acaaaaagtg gctagcattt gctagccttt
     1321 tttgtattgt ggagcgtggg ttttgagggg gattcaaggg ggagcttgcg cccctttgac
     1381 aagcggttat ttgcaccaaa tacggaggta tttggctagc aaatatagag cttgccaaac
     1441 actttagtga gttttgtaga aagtaccttt aaaggtactt tcacattacg aacgatacgt
     1501 ccgtaggacg tactgaaagg gtgggattta tgagcgaact aatgcaaaat ttggctagca
     1561 aaaaaagtta aaaaatatat gctaataatc gagcgaaatg aacacttttt caagtgagcg
     1621 aatccgccat gacaaagctg aagcagttta tttcagcttt gtcatggcgt gtgcctagac
     1681 ttttaaaaaa gtcggcacac gagcaaatat ctttatcaag ctctaatttg cgttttaaga
     1741 cgtttgaaac gtctaagtat ataaatatat aagagtaggt ttaagagtgc ttaaatcgaa
     1801 ttttagaggg cattcagaca actttagggt tgttagggct tgccctgacc gcctgtaagg
     1861 cgctttaaga acaagataag ggatttatac taagactgtc ttaaaacgtc tcaaacgaag
     1921 gctcatagct tctcaaagag ttccttatga acatttttag caaaggagcc ggaagcgact
     1981 gcgcagtata atgtgagagc agagcgatca caccttttta agcgactgta gggagtaaga
     2041 ttcccagttg agaaaaatgc gcgaatctgt ttggagaaaa aagaagtggt tttttaggcg
     2101 ggaaattttg tccccctctt ttataatctc tttttaaacc tctttttaaa cctctttacc
     2161 gtcggctata tccttactct cccaagggaa tgacgctttt atctacatcg ttttgtctgt
     2221 ttatctacat cgttttgtct gtttatctac atcgttttgt ctgtttatct acatcgtttt
     2281 gtctgtttgt acattgaatt agtacatcga cgatgttaat ataagatgta gataaacagg
     2341 cattttgtat ttcataacgt gtatctcttg tgcgagtaag aaaggagcta ttttaaatat
     2401 gtctaatgaa atcgtaaagt atcatcatga attaaataca attccgttgc gaaaatttac
     2461 accagtcgaa atgaatttgt tcttttctat cgtatcaaga atgcgtgatg taggtgataa
     2521 aaaagtacaa tttacattcg agcaattaaa agatttaagc aattataaag caactgcaaa
     2581 tgttcgattc atagatgatt tagaaacaac gtatgacaaa ttaatggatt tacgttttgg
     2641 tagaagaagt gctgacggtt tgcaacgtga acgttttgtt ttatttaatc aatttaaaat
     2701 cgacggaaaa tctgatattc cttttgctga aatacaagtt catgaaaaag ccttaccctt
     2761 acttaataat cttgaagaat gggtgcgcta ttctctccaa caattcaatg aattagaaag
     2821 cagttattca aaaacaatgt ttcgattact aaaacaatac agaaccaaag gtttcgctta
     2881 tttttcaaaa gaagactttc atgaattact tgatattcct aaaagttaca accaaggtac
     2941 gattgatcaa cgtgtgttca atccaatacg acaagaacta accgcaatct ttaaaggttt
     3001 aacaatcaaa aagaaatacg gaaaaggacg gggaaagcct gtcattggct atcaatttac
     3061 atttaaacct gagataaaaa aatcagacga ctttaacaaa catgccccaa caaaagaaga
     3121 acaaaacaaa gcattagaac tagctaacca acaagttcaa tctgaaaaag cacctacttc
     3181 attacaagaa aaaatcaaag aacaaaagcg aaaattggaa cttttacaac agttagaaaa
     3241 gttagaaaga gaacaaaata cccaaaataa agaaaataat gcacaaaaat cagagataaa
     3301 ttccgatatt ccttcagaac taaaaaaaga cttattagac aatcttcaaa acttattcaa
     3361 agattgaggg gtttttagat tttatgacag aaaaaacaat caaagaactt gctgaagaat
     3421 taggagttag taaaacagca attaacaaaa aagtttctga cgaaaatcga aaactttggt
     3481 tttcgaaaat cggaaacaag tttgtgatta atgaaaccgg acaaaaggct ataaaatcaa
     3541 tgttttttaa cgaaaacgaa aactcaaatc aacaactagt tggcgaaaaa acgaaaaccg
     3601 aaaaccacaa aaacgccaac caagttcccg aattagaagt cctttctctc ctagaacaac
     3661 agttaaatca aaaagatatg caactacaag aaaaagacga gcaaataaaa caaatgcaaa
     3721 aattactcga ccaccaacaa caactcaccc tgcaagccaa ccaacaaatc gagaaactgc
     3781 aggaacaact acagttgact tatacggaag aatcttcgga aaataaatca acgactcttt
     3841 ctgaagaaac agaatcgata gaaaaacaat caaaggcgga gaaaaaatgg tggcaattct
     3901 ggcaataaaa ccagcaattt aaattaataa aaattgctgg ttttattctt ctttttgctt
     3961 ttgcgagcag agcaacatgg acccatgttg cgatattttg gtggcgcccc aatccccgtt
     4021 ttttcgttga atcttactcg gactgcactc gttttacagc tgatttttct gaattttgaa
     4081 agagcataag gaaacgtggt atcactttct tacgaaaggt gctagatagg ctgtgcctat
     4141 cacgtttctc agaaaaaaat ttgctatcac ttttttgcca ttgtggctag gctatgtata
     4201 gtgttttggc gaaaaatagc tatacaaata ctatatttgt atggtataca taaattatac
     4261 gctgatacga aaggaaaatt tccatggaca ttttagttcg aaatatcaat cccaaaatta
     4321 ttgcaagaat agataaacgt tgtcaggaac tcacaaccaa aacgggcaaa aaatggagtc
     4381 gaaataaata tctaaaagtt ctaatcgaaa gtgattttga ccgtcaactt atgaattaca
     4441 aaaaagatca attcgattta ttactcgaaa aatttattgc cattcaaaca gaaaatacga
     4501 acatactgaa tgactatgtt cacacaaaca accaactcat tgaaacactt atcggaggaa
     4561 tataacatga gaaaaacttc tgttcaaaaa cacgtaaccc tttatcccag tcacgttgac
     4621 gttttagatt ccatcatcga aaaaaatcca gacgtcaaca attattcaga agccattcgt
     4681 tttttatgta tgagttatga acctgatacc aatacaacca caaccagtaa ccaagcaaaa
     4741 ctcaatgcca tgggaaaaga aatttctatc atgacagaaa tcatggcaga atttgctgat
     4801 ttatatctaa aagatactgg tgttcttatc ggtacaaatt ctaaagtgta tcaagaagtg
     4861 aaagaaaaaa ttgaaaatca actcaatcct tcccgacgaa atcaacccaa aaatcgtcaa
     4921 aaagaaacca atcaaacctt tacttctgga aattttgacc caacaaactt tctaaaaaga
     4981 taaaaaaaga aaccgatccc taaaaaaatt cctcgatttc tttttaggga tcagtcttcc
     5041 agcaagattt gcaagttggt accaacttgc gaaaaaaaag aaaaatccgc ttatgcaact
     5101 tcttcttttt gtattttggg gcgctacccc aatccccaag tatcggttat ttaatagcgc
     5161 ggaaatccaa agaataggac gtaccctgaa acaaaaaaag actgctctca cgagcagccc
     5221 aaaatgagat tatcctattc atcaacataa aaatattaca aagtgaagaa ctagagaaag
     5281 acaaaaaaag catatcaaat cctctcaaaa ataacaagtc tttaaaaaat gacagataaa
     5341 aatgcacaaa gaactaaaaa agagaaatcg cgtaaaatca agcattagaa gctagtaact
     5401 agctagacca attaaaaatc acaaagtgag cgtctctatc cattggtaga ggggctactt
     5461 ggtctagtcg acattatgtt aactagctcg ataaataacg attatgttcc caaaacaata
     5521 ttttatgaac tataacaaaa atttgttatc gcatattgta tattttaatt atataattat
     5581 aggtgtatac cacttaaatt taacacaaag acgtgattat tttgaaaccc aaaaagaaaa
     5641 tttatctagg tctcctcttt tccttgatga ttggaatttt tagtatagga attacaaata
     5701 cctatgcttc agaaaattct aatttcaata tcaactccca accaattgaa gaacaagcaa
     5761 ttaattttgc gaaaactgat tttgaacact ccataacttc aattctttta atggaaaata
     5821 acaccgaaac tgatattaac tatactcttg gttcgccatt taaaatgctc gatggagaaa
     5881 atacggcaaa tagttctatt ttctttccag tattttcaga cgctgataat acgattaaat
     5941 atatttatac cgtc
//
LOCUS       DADQDV010000124         5808 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.128, whole genome shotgun sequence.
ACCESSION   DADQDV010000124 DADQDV010000000
VERSION     DADQDV010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5808)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5808)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5808
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.128"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            549..1151
                     /locus_tag="J8S10_002872"
     CDS             549..1151
                     /locus_tag="J8S10_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAZ9631408.1"
                     /translation="MAKIGYARVSSKEQNLDRQLKALEGVSKVFSDKLSGQSVERPQL
                     QAMLNYIREGDIVVVTELDRLGRNNKELTELMNQIQIKGATLEVLNLPSMNGIEDENL
                     RRLINNLVIELYKYQAESERKRIKERQAQGIEIAKKKGKFKGRQPKFKENDPRLQHAF
                     DLFLNGCSDKEVEEQTGINRRTFRRYRSRYNVTVDQRKKQ"
     gene            1167..1844
                     /locus_tag="J8S10_002873"
                     /pseudo
     CDS             1167..1844
                     /locus_tag="J8S10_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
     gene            2356..2652
                     /locus_tag="J8S10_002874"
     CDS             2356..2652
                     /locus_tag="J8S10_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombinase"
                     /protein_id="HAZ9631409.1"
                     /translation="MSKGFLEPALFNQERNVLDSEIKNLTTEKTNLVTNSASGVLRAN
                     EIKDLINYVSADNFNGDYTEELFEEFVVNIIVNSRDELTFNLKCGLSLKEKVVR"
     gene            2653..3069
                     /locus_tag="J8S10_002875"
     CDS             2653..3069
                     /locus_tag="J8S10_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="HAZ9631410.1"
                     /translation="MAYIPYGYKIQDGVVTVDEKAAGQVKVFFEKYISGLSLTVAGEQ
                     AGIEKTHSVMGRILKNVNYLGNDTYPAIIDKEIFDKAEEVRDKRAKDLGRVVELAAFT
                     SPPPKERFKMKKADNKMPVDPFERAEYLYSLIESEE"
     gene            3089..4633
                     /locus_tag="J8S10_002876"
     CDS             3089..4633
                     /locus_tag="J8S10_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018659190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAZ9631411.1"
                     /translation="MVIPARKRVGSTAAKEKIKKLRVAAYCRVSTETEEQNSSYEVQV
                     SHYTEFIKKNNEWEFAGIFADDGISGTNTKKRDEFNRMIAECMDGNIDMVITKSISRF
                     ARNTLDCLQYIRQLKDKNISVYFEKENINTTDAKGEVLLTIMASLAQQESQSLSQNVK
                     LGLQYRYQQGKVQVNHKRFMGYTKDEDGNLTIVPEEAEIIKRIYREYLEGQSLVGIGR
                     ALEKDGILTAAGKPRWRPESVKKILQNEKYIGDALLQKTVTVDFLTKKRVKNEGHVPQ
                     YYVENSHEAIIPKELFLQAQEEIHRRSNIYTGEGKNKRIYSSKYALSAITFCGDCGDI
                     YRRVYWNIHGRKEFVWRCVTRIEQGPEVCKNRTVKEDELYGAVMTAINKLLAGGNNMI
                     KTLEENIHAVIGETTEYQISEINNSLEEKQKELIKLANKGQDYDHLADEIDELRDKRQ
                     ILLVEDASLSGENERINELIEFIRKNKFRTLEYDDKLVRKIIQSVTVYEGHFVIAFKS
                     GIEMEI"
     gene            4776..5000
                     /locus_tag="J8S10_002877"
     CDS             4776..5000
                     /locus_tag="J8S10_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018579902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAZ9631412.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGEEIKISNE"
     gene            5015..>5808
                     /locus_tag="J8S10_002878"
     CDS             5015..>5808
                     /locus_tag="J8S10_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HAZ9631413.1"
                     /translation="MVGNVIQIVTEKLSSLPFIEGIVLGGSRARGTHTENSDIDIGIY
                     YNSDSFDLTAINQIATELDDENRNNLVVPPGAWGDWVNGGGWLVINGCHVDLILRDIK
                     RVEQIIKDTEQGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAEIY
                     PTALKKSLMNFFIFEAEFSLMFVKANAGAEDKYYIAGHVFRIISCLNQVLFACNNAYC
                     INEKKAIKLLETFEYKPEKYAERVNHIFEVLGLSLFECYDMTEKLY"
BASE COUNT         2072 a          923 c         1233 g         1580 t
ORIGIN      
        1 tttgagctat gtacaagaag cattttattc tagcttaatt tgacaaatca tactatgata
       61 cgtgtttgtt tttctgtgct gtttagtgaa tgattagcag aaatatagag agtaagattt
      121 taattaatta ttagggggag aaggagagag tagcccgaaa acttttagtt ggcttggact
      181 gaacgaagtg agggaaaggc tactaaaacg tcgaggggca gtgagagcga agcgaacact
      241 tgatctttta agttgctatc tttttaaggt caatagagta tacttatttg tcctaatatg
      301 gttttagcag tataattgac ttggtgaata ggtcatttaa gttgggcata ataggaggag
      361 taaaatgaaa aaatttattt atcgagtttt agaaaatgac gaagtggtgg ctatttttaa
      421 tgagcaacaa tatgcgcaag attttatcgc ttacgaaaag acaatttctg ataagcaatt
      481 tgaaattgaa aaagtagata tagctgattg gttattgcaa ccgagagaat tttagaggtt
      541 ggttgaaaat ggctaaaatt ggttatgcac gtgtcagtag caaagaacag aacttagata
      601 gacaactgaa agcgttagag ggcgtttcta aggtcttttc agacaaatta agcggtcaat
      661 cggtcgaacg cccacaatta caagctatgc ttaactatat tcgtgaaggg gatatagttg
      721 ttgttactga attagatcga ttaggacgaa ataataaaga attaacagaa ttgatgaatc
      781 aaattcaaat taagggggca accctggaag tcttaaattt accctcaatg aatggtattg
      841 aagatgaaaa tttaagacgg ctgattaata atttagtgat tgaattgtat aagtaccaag
      901 cggaatctga acgcaaacga attaaagaac gccaagccca aggaattgaa attgctaaga
      961 aaaaaggaaa attcaaaggg cgacaaccta aattcaaaga aaatgatcca cgtttacaac
     1021 acgctttcga tttatttttg aatggttgtt ccgataaaga agttgaagaa caaactggaa
     1081 ttaatcgccg aacgtttaga aggtatcgat caagatacaa cgtgacagta gatcaaagaa
     1141 aaaaacaatg aaaagaggga tagttaatga gtacggttat tttagctgaa aaaccaagcc
     1201 aggcattagc ctacgcaagt gctttaaaac aaagcaccaa aaaagacggt tattttgaga
     1261 tcaaagaccc actatttaca gatgaaacgt ttatcacctt tggttttggg catttagtcg
     1321 aattagcaga accaggtcat tataacgaaa agtggcagaa ctggaaactt gaatctttgc
     1381 cgatttttcc tgatcgatac gattttgaag ttgcaaaaga taagggaaag cagtttaaaa
     1441 ttgttgctga acttctcaaa aaggcaaata caattattgt cgcaacagat agcgacagag
     1501 aaggtgaaaa tatcgcctgg tcgattatcc ataaagcaaa tgccttttct aaagataaaa
     1561 cgtataaaag attatggatc aatagcttag aaaaagatgt gatccgaagc ggttttcaaa
     1621 atttgcaacc aggaatgaat tactatccct tttatcaaga agcgcaaaca cgccaaattg
     1681 ccgattggtt gatcggcatg aacgcaagcc ctttatatac cttgaattta caacaaaaag
     1741 gcgtacaagg tacattttca ttaggacgtg tacaaacacc gactttatat ctcatttatc
     1801 aacgccagga agcaatagaa aactttaaaa aagaaccttt tttcctgaat aattcatagt
     1861 tttactaata gtctttccta acattgattt aatagtcttt aaagtattct gcttcatcac
     1921 ccattaggtg atgaaaaaag aacccctttc tgatttagcg gacaaatact ttgacctaat
     1981 ctcagaagat ataaaagaaa aaataataaa atatccgatt tatactttgt ataaagaact
     2041 aaagtagtta gcaaatcatt tacagcaaat cactatgttc cacataccat tttacatact
     2101 taccttatcc acgacacatg ttgagatagt atcgaagata aagaaagttg ctccatgttg
     2161 tttttgcgag atggggaaat caaagccaca ttgacaacca tgatgaataa gcttgctttc
     2221 agtcataagc taatcctaga accacttttc aagtcagtta gccaaatcga tgaagaaagc
     2281 gaccgtgaaa gaatggacgc tattgataag ctaatggagc aactattgga agaacgcaat
     2341 acccttattg cactgatgtc caaaggtttc ctagaacctg ctctttttaa tcaggaacga
     2401 aatgttttag atagtgagat taaaaatctt actaccgaaa aaacaaacct ggtaacgaac
     2461 tctgcgagtg gggttttgcg agcaaacgag ataaaggacc tcattaatta tgtgtcagca
     2521 gataatttta atggtgacta cacggaagaa ctatttgaag aatttgtagt gaacatcatt
     2581 gtaaattcca gggatgagct gacattcaat ttgaaatgcg gtctttccct gaaagaaaag
     2641 gtggtgagat aaatggcata tattccatat ggatacaaaa ttcaagatgg agtggttact
     2701 gtcgatgaaa aggcagcagg tcaagtaaag gtattctttg agaaatacat atcaggacta
     2761 tcccttacag tggctggcga acaggcaggt attgaaaaga cacattctgt gatggggcgc
     2821 attttgaaaa acgtcaacta ccttggaaat gatacgtatc cagcaattat tgataaagag
     2881 atatttgata aagctgaaga agttagagat aaacgtgcaa aggatttagg acgagtggta
     2941 gagcttgccg ctttcacctc tccccctccc aaagaacgat tcaaaatgaa aaaggcagat
     3001 aataagatgc cagtggatcc ttttgaacga gcagaatact tatacagtct gatagaaagc
     3061 gaggaataaa gtgacagaga aaaatataat ggttattcct gctcgtaaaa gagtaggaag
     3121 tacagccgca aaagaaaaga taaagaaact tcgtgttgct gcctattgcc gtgtttctac
     3181 agaaacagaa gaacaaaatt ctagctatga ggttcaggtc tcacactata cagagtttat
     3241 aaagaaaaat aatgaatggg agtttgctgg catctttgca gatgatggta tctctggtac
     3301 gaacactaaa aagcgtgacg aatttaatcg catgattgca gagtgtatgg acggtaacat
     3361 cgacatggtt attacaaaat ccatcagccg atttgcgcgt aacaccctag actgccttca
     3421 atacattaga cagctcaagg ataagaacat atcagtttat tttgagaaag agaacatcaa
     3481 caccacggat gccaaaggtg aggttttgct gactattatg gcatctttgg cacagcagga
     3541 aagccagagc ctttcacaaa acgttaagct tgggctacag taccgatacc aacaaggaaa
     3601 ggtgcaggtc aaccataagc gatttatggg ctacacgaaa gatgaagatg gaaatttaac
     3661 tattgtcccc gaagaagctg agattatcaa acgcatctac cgagaatacc ttgagggtca
     3721 gagtctagtg ggcattggtc gagcccttga aaaggatggt attttaacag cagcgggaaa
     3781 accaagatgg cgaccagaat cagttaagaa gatacttcaa aacgaaaaat acatcggaga
     3841 tgcccttctg caaaagactg tcacagtaga ttttctgacc aagaaacgag tgaaaaatga
     3901 agggcatgtt ccccaatatt atgttgaaaa tagccatgaa gcgattattc ctaaagagtt
     3961 atttttgcag gcgcaagaag aaattcatcg gagaagcaat atctacacag gagaaggcaa
     4021 gaacaaaaga atttacagta gcaagtacgc tttaagtgcc atcaccttct gtggagattg
     4081 tggcgatatt tatagacggg tctattggaa tatccacgga agaaaagaat ttgtctggcg
     4141 atgcgtgact agaatcgagc aaggtcctga agtttgtaag aaccgaaccg taaaagaaga
     4201 tgaactttat ggtgcagtaa tgactgcgat taataagcta cttgcaggtg ggaacaatat
     4261 gataaagaca ctggaagaga atattcatgc tgtgattggc gaaaccacag aataccaaat
     4321 ttcagagatt aacaactcac tagaggaaaa acaaaaagaa ctaatcaagc tggcgaacaa
     4381 gggtcaagac tatgaccact tagcagatga gattgatgag ctgagagaca agcgacagat
     4441 ccttttagta gaagatgcct ccctcagtgg cgagaacgag cgaatcaatg agctgattga
     4501 atttatccgc aagaacaaat tccgcacctt agaatatgat gataagcttg taaggaagat
     4561 aatccagagc gttacagtct atgaaggcca cttcgtcata gccttcaaat ctggcatcga
     4621 aatggaaata tgaaaaccag aagtaaatag cccatgactc tacagtagag ttgtgggttt
     4681 tcttttgctt gctgattata ataatatttt aataactatt gtgtttatca accaaatggt
     4741 ttataatatt cttagcgtaa acttggaggt gctgtatgac tacggcagaa atgattaaag
     4801 aactgtgtga gcaaatgaat ataagtgttt ccgaacttgc tagacgtatt ggccagactc
     4861 cacagaattt caataaaaaa ttacaacgag aaacagtaac cttggatgag ttgaaggcca
     4921 ttgctgatgt gctaggtgtc aagtttgtgc aggcatttat tttaccagat ggagaagaaa
     4981 taaaaatatc taacgaataa aggaggatgt ttatatggta ggtaatgtta ttcaaatagt
     5041 aacagagaaa ttatcatctt tgccttttat agaaggcatc gtattagggg gctcacgtgc
     5101 aagaggcacc catacagaaa attctgatat agatatcgga atctattaca attcagactc
     5161 atttgacctg acagcgatta atcaaattgc tacagagttg gatgatgaga atagaaacaa
     5221 ccttgttgta cctcccggag cgtggggtga ttgggttaat ggcggtggat ggttagttat
     5281 aaacgggtgt catgttgact tgatattacg tgatataaaa cgggtggaac aaataatcaa
     5341 agatacggag caaggaattg ttactgccaa ttatcagacc gggcatcccc atggttatat
     5401 aagtgctatg tatcgtggag aattagcgat tagtaaaata ctatatgcta agaacgaaag
     5461 cttatgcgaa ttaaaaaagc aggcagaaat ttaccctact gctctaaaga aaagcttgat
     5521 gaactttttt atatttgaag ctgaattctc tttaatgttt gtaaaagcaa atgcgggggc
     5581 agaggataaa tattatattg caggccatgt ttttcgtatt atttcatgct taaatcaagt
     5641 actatttgca tgtaataatg cttattgcat taacgaaaag aaagctataa aactgcttga
     5701 aacttttgaa tataaacctg aaaaatatgc cgaaagagtt aatcatattt ttgaagtact
     5761 cggtctttct ctttttgaat gctacgacat gaccgagaaa ctttataa
//
LOCUS       DADQDV010000125         5769 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.129, whole genome shotgun sequence.
ACCESSION   DADQDV010000125 DADQDV010000000
VERSION     DADQDV010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5769)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5769)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5769
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.129"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(1014..1304)
                     /locus_tag="J8S10_002879"
     CDS             complement(1014..1304)
                     /locus_tag="J8S10_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631414.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            1646..1942
                     /locus_tag="J8S10_002880"
     CDS             1646..1942
                     /locus_tag="J8S10_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631415.1"
                     /translation="MQIGVLKWLQFTKQKGVHFPMQFLEPKNKNAKSVDWEISEQVRV
                     IVKQYAEYAERTESEAVDEFLLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            1949..3901
                     /locus_tag="J8S10_002881"
     CDS             1949..3901
                     /locus_tag="J8S10_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HAZ9631416.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(3973..4470)
                     /gene="dfrG"
                     /locus_tag="J8S10_002882"
     CDS             complement(3973..4470)
                     /gene="dfrG"
                     /locus_tag="J8S10_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HAZ9631417.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(4797..5489)
                     /locus_tag="J8S10_002883"
     CDS             complement(4797..5489)
                     /locus_tag="J8S10_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HAZ9631418.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
BASE COUNT         1894 a          996 c          917 g         1962 t
ORIGIN      
        1 atacttgcaa agtaatacta caattcctaa cataatcgta gaatttaata atttccatag
       61 cataaagtgt ttagaaaaga acattaagaa tagttctata ataattcttg aactccatgt
      121 cttataatgt tctatcgaag cacccaaata gccaagttca tctaatctac ttgcataaac
      181 tacgtcatcc gctctcatag tcggcatata catattaaag agtaaaaaga taccccaaat
      241 ccctattagt aacaagatca gttctttgtt attcgttatt tttctattat gtttgttcat
      301 ttttatactc cttcttatat ttcctaatag agtataacat agctttaagc attacttaaa
      361 gataacttaa aagttatctt ttaaatactt aattgttaaa taccttattt gatgcaaaag
      421 aaatctacga tagtcaacaa aaaaattttc attatatcca gaaaaatttt tcttagttaa
      481 ggacctatgg attgcagtaa tgcagaattc gtcgaataaa ctgccaaaga catacaatca
      541 tattgctttt aaaattgacg aacaagatat agattcgttt gtctcaaaaa tccaaatgtt
      601 aggtttaact gtcgaaccag gacgttctcg tgtgaaaggc gaggcttctt caatttactt
      661 ttacgactat gataatcacc tcttcgagtt acataccggt actctccagg aacgtttaaa
      721 atcctacaat tccactacct gagactagta atgactagtc tctttttatg gcctctgatc
      781 cccccattga gcgaatacta atagggcttc gaattgatct gttcaatctt taagcaatat
      841 ccctcaaatg agtttggaaa gtttagtgat tcatcacaaa tacttaaata catgtagtta
      901 tatatagatt gaggttcttg tgagcgtatg ctcgtgtggg ttcaaatccc atcgtctgca
      961 tccatctttc caaaacaagc ggctaggaca tttttgtctc agccgcttgt tttctagttt
     1021 attctttcat cttgtcggac cttttttctt gggtatagac ttttctcata ttctaccaca
     1081 attttgggtt tccctaacac atgataggat ctcacaacaa attgctttct attattataa
     1141 taacctgtaa cgactaactt catcccttcg tctacttcag ctaggaagtt caaactatgg
     1201 gaagcaatca aacaattgac cccatttaaa ctgaaacgga tcaacggtct ggcactaact
     1261 tgcaaagtac ggatcttatc tactgttcca tattttttct ccataacctt cacctcaata
     1321 ccattatacg aacatacatt ccctttgtaa agaagaaact ctgttttatc tttttgactt
     1381 tttgtctatt acctttctta aaatcatatt ggcacttcct gcgaagatga aggacatgta
     1441 ctaaaaaaaa gaggcagcag tatagattta agtagttcag ttttggagta caaaaagtga
     1501 aaatgtaaac ctaaatgagt atcaaattgc aactgaattt gatactcgtt ttttattgtt
     1561 aaatcaacgt ttgttgttaa tttacaccac aaaatgtaag ttaaaatgta tataaaaatg
     1621 cgaacgtgaa ataattattg taggaatgca aattggtgtg ttaaaatggt tacaatttac
     1681 taagcaaaaa ggggtgcatt ttcctatgca atttcttgag ccaaaaaata agaacgctaa
     1741 gtctgtggat tgggaaatat cagagcaagt aagggtgata gttaagcaat acgctgaata
     1801 tgcagagcgt actgaaagcg aagcagtgga tgaattctta ttgaacattt tagacgataa
     1861 gaagtttatt gaatggattg ccaacaagcg aagtaataag cggattgttg aaaaaatggg
     1921 tatcaaagat agagtgggtt gatagacaat gaccaagctt aaaagattag ccacgaagga
     1981 agatgaaatt gtagatgtta aaattccgat ttcaaacgaa gaattaaaag atagggctaa
     2041 acaatatgat ttattaactc caaaacgatt tgcaacaagg tataacaaaa tgttgttctt
     2101 gccaacgtct tttaaatgga acggttctga atatcccatt caatataatt actgcatcaa
     2161 tccgttttgt tgtaattttg ggaaagaaca gcacaaattc aaagatgtaa aagggaaacc
     2221 aagtcgatat aaaatgactg gtagttccaa agataaaggt cataaaggta tgtactgcaa
     2281 tgacaatcct attggcagag gtgtatcgca aaactgtaca gtaacccctt tatctaattg
     2341 gtctgttgtt gaagaaatta aacgccttat agaaatcaat agcatccaag atgttgagcc
     2401 agattatcaa tttcataaag aaggctgctc ggaagaagaa tcaaccccat tcaatgagcc
     2461 gaagcaattt tacaaaaggg ggaaaagtag gggcaaatct caacgctatc aatgtaaggc
     2521 gtgtaagaag ttcactaatg ttctaccaaa aagagaagaa accactactt atcaccaaca
     2581 aaagaacacc attcttccaa tgttcgctaa gatggttgtt ggaagggttt cagtcagtcg
     2641 tacttgtgat attttaggaa ttggagttgg aacctactat cataagctgg agtggctgta
     2701 taggcgttgt ttggagtttt tagaacgata tgagacacaa ccccttcaaa caaagaaatt
     2761 taacgagatg tggcttaata cggacaagat gcactactac ctaaataacg tccgtaagaa
     2821 aggacaaggt tcaaagaaat atacggggtt tgaagacctt aatatgcaaa cgtatatagt
     2881 tgtatctgct gaggtcttat caagatatgt gttccgttct gatgttgcct atgattggaa
     2941 tatttcaatg gatgaattaa atgaagatac aagaaaattc aaagaagacc atctcaatac
     3001 ttttagtcgt aaaaatgata ggttagattg gtcttattat ccacaagaac catccgctaa
     3061 cgatagcgaa aataggaatg cttatcttca cgaattaggg aaaattacta ataggagtag
     3121 atttgtcgat ggtttaaatg ttgatgctcc ttatactaca actgctcact attggttaat
     3181 taaacaaatg gttaatgccg acgaatggcg aatgattagt gatgatgact tctctattag
     3241 aaacgccttt tatagagtat tcacgaaaga attaaggttg agcgatgcac atcattttat
     3301 ttgccaagtt aacaagacga aaagcagaaa acaatgctta aaagaattcg gacaagcaaa
     3361 agcagaactg ctcgattggg gagatatcag aggattcaaa acaaagtttc tacggacttt
     3421 ggcatctcat tatctaactg aattactaac aagtcatcaa ttccacgaag aggctattag
     3481 taaagatgga gaaagatatc gcaaatatgc cgataaccct atcaaacatc cattagccac
     3541 taaggataaa ggattttatt cagttgattg tagaacggat ttatctgctc tggaaccaaa
     3601 cgaaatcgca aagatgctat taaatgttaa tgaccattcg accaatagct ttattcaaca
     3661 gataagacgt tatatatcat ctcttgaaag accattaaca acagctcgtg gtgataagaa
     3721 gagctatatt tacgctaact tcaatccgaa gtatgctcaa tttgcgatta caattctaag
     3781 aacttactac aacttttgtc gcccttttaa atcagcggat aaaaaggttt tgacacctgc
     3841 tcaaagatta gggattacag ataaacaatt tgattggaaa gatataattt atttcaaatg
     3901 acaaaaagag cttggagtaa tcccaagctc ttgtgcttta tctttactgt tcttcttcaa
     3961 ttaacgcacc cgttaactca ataagttttt tctttcatat acatgaaaat agtagttata
     4021 cggattttta tcattcttta tccctttttg ggcaaatacc tcattccatt cctcataatt
     4081 cacttctgga aaaaaagtat ctccttcgaa ttcatgatgt atttttgtga tgtacatttt
     4141 ctcaacataa gggaaaaaca aattataaat ctgttctcct ccgaaaataa aaatttcttc
     4201 ttcgttttta cataactcaa aaacatcttc tattgaatga acaatttcac aaccattaaa
     4261 ggtaaacccc ttatctctcg tcagaataat atttcttctg tcaggtaagg ctcttccgat
     4321 tgattcaagg ttcttcctac ctaatattat cggatgtccc tttgtagtat ttttaacata
     4381 ttcccagtcc ttgggaatcc tccaaggaat gtcattctct ttgccaatca ctctattctt
     4441 atccatcgca gcaatcaaag aaactttcat ttataacaca gcctttttaa ctaatttacc
     4501 atctaatttc ttatttctat caaaaaacct tttctcatta tcctgcccgt tagttgaata
     4561 agcaattttt tctataagtt atattatcat aataccacaa aatcacaaat tttcattcaa
     4621 ttatcatttt caattgcatt ttataaatca ttttgtatgt aatttggtat gtaagttaaa
     4681 atgaaaaaag tagtccattt tgaagtacat tttgtcattt tgtactccaa aactgaacta
     4741 cttagtatag attactgttg cttctttact aatttaggtt tacttgttaa gaaagattat
     4801 ttacgcaaat gttcttcaac aatttgctga gatttatcag ctgtatcttc cacttcatct
     4861 tttgcttttt ctaacttttg aatatattgt ttcaagcttg agttttcagc agttgcttcg
     4921 tctaatttct tttgtgtatc tgttaactga gtttctacat ttgttttttc ttgtgtcagt
     4981 gttgcgattt gttgattcaa accatttaca gtattttgta attctgaaag ttttgcttgt
     5041 gcttcttgta gtcttgctgt ccaatctgca ttcagatgat tgatttcatc atttttttgg
     5101 ttgatctcat ctagtttgac attgatttca ttttgtttgc tttgtagttg tgcatccttg
     5161 ctgactaatt gactttctaa gttttgtttt tctgctgccg attgattttt ttggttttct
     5221 aattcattta cttttgtttg gtattcttgg acatctgcct ttgaatcttg caatgtctgt
     5281 tctttttgtg ctagtcgagc ggtaagatct gtaatcgctt gctctttatc tgtcaatgta
     5341 tgatcaagct gtgtcagatt ctcattgatt gtatcaatat ctgtctctcc accccacaaa
     5401 ataatttcat ttgcgtaccg cgtgcctgtg tagccaatta gacatagaaa tgcaacgaca
     5461 atcccaccag taataaattt ctttttcatt tgcatagctc cttaatccaa tacttttaca
     5521 tgctaaaagt aagtgatctc aaacacaatg tcaagcgttt ttaaattaca tatgtaattt
     5581 taatataaat actatcaaat actcatttaa tcctcctttt ttatctattt aaaaaatctt
     5641 ttttatagag aaaaatgcag gttaatactt tcttaaataa atatttatgg tgaacaaaaa
     5701 caaaaaagca agttttatta aacgtaaccc ttttcatttc atagattact gtatttatta
     5761 caaaaaacg
//
LOCUS       DADQDV010000126         5697 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.130, whole genome shotgun sequence.
ACCESSION   DADQDV010000126 DADQDV010000000
VERSION     DADQDV010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5697)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5697)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5697
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.130"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            127..579
                     /locus_tag="J8S10_002884"
     CDS             127..579
                     /locus_tag="J8S10_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631419.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            593..1282
                     /locus_tag="J8S10_002885"
     CDS             593..1282
                     /locus_tag="J8S10_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631420.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1407..3758
                     /locus_tag="J8S10_002886"
     CDS             1407..3758
                     /locus_tag="J8S10_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HAZ9631421.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            3838..4233
                     /locus_tag="J8S10_002887"
     CDS             3838..4233
                     /locus_tag="J8S10_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631422.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            4558..5175
                     /locus_tag="J8S10_002888"
     CDS             4558..5175
                     /locus_tag="J8S10_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAZ9631423.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            5216..5515
                     /locus_tag="J8S10_002889"
     CDS             5216..5515
                     /locus_tag="J8S10_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631424.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
BASE COUNT         1990 a          758 c         1149 g         1800 t
ORIGIN      
        1 attcctcctg ctatcttttt ctattattct atcttatttg atagtagatt taaaactttg
       61 caacagaacc aattatctta tcgtagatat atattataaa tttaataaga aagcgaggtg
      121 agaatcgtga aaaaaacgat actaagtatt ttttcagtat ttacaatatt aattgggggc
      181 tattttcttt tgaatttaga ttctgttaat tcaaacgctc aaataaaaga tcaaagagta
      241 gctgaacata ataataaaaa aatgagtttg accaaaaata tctattctat gtcagatgaa
      301 gaattgtata aagaatttgg tgatttatcc ggggaacagt tagaagaaag tattccagga
      361 attagtgact cagataaaat tgttgtcttg tctgctggtg ggcaattaat gggagatggc
      421 aaatccgaat tagttagtta taaacaaaat cacagacagt ttattgatgt taatactgat
      481 tccaacgcta tttcgattaa ggatctaaaa gagcttttaa atagtaaaag aaatgaatta
      541 aagcagataa aagaaactaa ttcagtggaa ttagagtaaa ggaagattca ttatgaaaaa
      601 gatttttggt gtttctgttg ggctacttat gatgttaaca tttggaaatg cagtatatgc
      661 tgctgagaaa gaagttattt cagatccaga gcagtacgcc tcacgatact ttgctgattt
      721 tgaagaagaa gataaagtac ttgcattgcc agaaggtggt tttttaaaag gggaagctaa
      781 aattgtatct atggataatc cagatataat tcaaggttca tataattcag aaactgatcc
      841 tgcttcagtt tcagtgacag aagcaaaaaa aattgttgct gaaaaattca aaaatgatat
      901 tgaaactact ccaattatgc ctcgaggagc atttccaccc gatgttggta ctagcggaca
      961 ccttcttgta ctagcaggag gaggaagcta taaatcacag ccatttagtg gtgcgggatg
     1021 gcgttttgga ggtatgggtg taaaaccagc tgatggtaca ggcaactttt tacgttggaa
     1081 atcctacatt gacgatggaa gagtaggaaa tgtaaatcaa gccaacgcaa ctaaatctgg
     1141 ttctattcaa ggaatggcat tgtatgctcg tgaaggattc aaatactttg caccaaacgg
     1201 gcctggttgg acaatgaata taggtattta ttacacttat aatcctgttg caggtacgta
     1261 ttatgttgtt caaaatattt aataaaacag cacaaagaga tttctttgtg ctgttttatt
     1321 atttttagtt gttgacaaac actaaaatat aaaatataat caacacataa acgaacgtat
     1381 gttcggcaag aaagcagggg atttttatgg atgagatggt tttaagtact cagaaatggc
     1441 taaacaagaa atacagtaat gttacagggt ttgataaggt tccagaaaat gggcgaacag
     1501 ggtggcctac aatctatgga cttattgaag gactacaagt agaacttggt attactaatc
     1561 tagtagctaa ttttggacct accactgaaa aaatgtacga taatcaggtt actcctaaat
     1621 ggggcaaaaa tctacctaaa aatattgtat ttcttattca aggtgccttt tggtgtaagg
     1681 ggattaatcc aggtggcttc gatggggtat atactccata tttagatact gctgtaaaag
     1741 agttgcagac tgatgcaggg tttaatggaa gcgctgtaac tggagttttg gatgcgaaat
     1801 gggccaaagc gttatttgat atgagtgctt ttgttcttgt tcccggcgga gatagtaaaa
     1861 ttagaaaaat gcagcaatgg ttaaatgtaa attatttaga atacacggga ataatgcctt
     1921 gtgatggtat ttatcaaaga aattcaaatc aagcattaat ttttgcatta caagctgaac
     1981 taggatattc tcccagtgaa gcaacagggt cttatggtaa tgggacaact agtaaaactt
     2041 atcctgtgtc tgaaggtaac tcgggaaact atgtaagaat aattcaatat ggattatatg
     2101 ttaatggtta ttttgaagac ggtacattcg atggtatttt cactaaatat atgggtttag
     2161 aagtactggc attccgaaaa tttatggtat tgcctgaata tactgaaata gcagatgttg
     2221 ttgtaataaa aggactattg tctagcgctg gagatattag aagatctgca gatggcgcag
     2281 atacttctac gcaattaact agatctcaaa tccaaacatt ggttgataat gatataaaaa
     2341 tagttggtag atatcttact ggtactgttg gaattggaaa agatgaacga aataagtatc
     2401 taactacaga ggaattgaat aatatttttt ctaaaaattt atctgtgttt cctatctatc
     2461 aagatggagg tgcagcatta gcttatttta cttatgatcg tggcttatca gatggtaaga
     2521 aggctataga tgcagcaaaa aatctaaata taccattaac aacagttatt tattttgctg
     2581 ttgatctaga catgttaggg gaagaaattc ttgcatatgc tggagaatat tttaaggggg
     2641 tatctgctgt aatgtcatat agcgggtatc aaacgggtgt ttacggaaca agaaatgttt
     2701 gttctcaaat aatcaataac gggtatgctt cgtttgcatt tgtttcagat atgtcgactg
     2761 gttatagtgg gaatttaggt tttcctatgc ctagacaatg gtcttttgat caatttgttg
     2821 aatttaccat aggaagtggc aacggagctg ttggtatcga tttaatcgct acatcgggta
     2881 gagatagcgg atttaatgag ttatcaaatg atactaataa tgataattac attgccaaat
     2941 acaatcagaa ggttataaat cagatggtac gtgcgtatca atatctatca caagctggtc
     3001 ttgataatcc ttggaaccct catttgacat tttatagata tgtaaattat tctggtttgt
     3061 catgggacat catttcttct cctgtaacag agcatgatag aaaaatttat gatgaatata
     3121 ggaataaatt aactaatagc gagggcctgt ataattattt tatagatcct aatactggtt
     3181 caataatagg tttgcctcac ttaattgtga cgttacaatc acagatgttt ctagccgaca
     3241 caatcaatga tagtgtttct gactttgcag gttggttagg agatttaatg acttgctggg
     3301 gtgaagttaa gaaattagga atacaaatgg agcaaggtgt atttgcatta gtaggtacgg
     3361 ctgcaggtgg aacatttagt ctagaagatt tataccaaga tgttgacgcg gtaaatgttt
     3421 ataccttagc aaaaagaaat tctgattcaa cagctttatc ggctttaaaa acgtactatt
     3481 gtgataaggg tgctattgat agatttaatc aatttgttaa gaacagattt ggttcttcag
     3541 ataaaatcgc ttcagtaaca aatagtttat tagaaaatga cgaaacagtt gatatcttag
     3601 gtgtagggat aatttcattt ttcattgata aaatagttaa taattcactt gggacagatt
     3661 ttacttatct tgattttatt ggagatgagg ggaaagttgc aaatggattt tctgaaaaaa
     3721 ttattcaatt tcaagaaaat agaagtaaac ttaattaaga atcgtttact atttaaacag
     3781 tgtccttttc ctttttaaat atatacgata aaataagtat atgaattgta aaaggacatg
     3841 atgattatgg aagaaataga atggaataat ctgactcaaa ataataaaaa taattctgga
     3901 tgtggaatta tctttatgtt tgttatagtt ttgggaatag tagtactttt aataactgtc
     3961 aagatagtag attactttgc gaatactcct gaagaacaaa tacagagaaa acttcctgag
     4021 tttgaaagag taccacctta tgatccaaga gataattcat ttcaagtaaa aaaattaaaa
     4081 gagtctccaa atgaaatgtg gtttgaagtt acagttgaat caagcgactt caaagaaaaa
     4141 aagaaagaat acaattatat tgtaaaggca aaagtatcaa aaagatttat ttttaaccct
     4201 aaattagaaa tatatagtgt tgtaatagaa taatagtgtt aaaaaaattg taaaagttaa
     4261 agaagtcaaa ttctgatgtg aaaaataaaa tataccatgg aagacataaa agaaaaactg
     4321 gataactagt ttatttaatg gcagaccgtt aaggcctgcc atttttatgt attttagcgg
     4381 aataaatata atcatgcggg agtgtaaact tactgtttca aaaagtatac tttttgacat
     4441 gccttgattt tctttgttta tgtatggcat aataaccaca taatacaatt tgaaacgttt
     4501 ctgatttaat ctgattgttt tgaaacaatt ttagtgaaaa aagggtagat aaaaacgatg
     4561 agaaaatttt tttatatccg ggtcagtagt tatgatcaat cgatcgaacg acaactgatt
     4621 tccgcgaagg aattaggaat ccctgaagaa tatatatttg tagaaaaagc cagcggcaaa
     4681 gattttaaac gccctgaata tcaattaatg aaacggatgt ttcgaaaagg agatttactc
     4741 tatctacaat cattagatag actaggcaga aataaacaaa tgattttaga agaatggcga
     4801 gaattaacta aggaaaagca gattgatatt tctgtgttag acatgcctct gttagatact
     4861 gctagttaca agcaactaga tgggttagag acgcttatct ctgacttaat tctgcaatta
     4921 ctcagctata tggccgaaga cgagcggaaa cgaattaata gccggcaaag agaaggcgta
     4981 gaagctgcga aacaaaaggg tgtaaaattc ggcagaaaga aaattgcttt acctcctgaa
     5041 tttcctgcga tctattctga ctggaaagca ggaaagataa ctgcagtcta tgctatggat
     5101 caattgggca tgaaacgaaa taccttttat cgacgggtga aagaatatga acataccttg
     5161 caccactttt cttgatagat ataacagcta ttagacggga agggagagtt tgaaaatgga
     5221 cttaacgaat caaagggtcg tttttactgg aacgctgcag caaatgacac gaacccaagc
     5281 catcggtttg gttcactctt taaacggcca ttgtcaatca agtgttactt caaaaacaaa
     5341 tttcctggtt tgtggtcagt attctaagtc gttgtttgat gattctctct atacaaaaaa
     5401 ggaacaaacc gcgcgggact tgattgcgtt aggtcatgag attaccattt tatcagaagt
     5461 cgaattttat gcgttaatta gtcaacagtt gaaagaatgg caacggtatt tataatcgtt
     5521 agtaaaattt acaaggagga aaatttttat gaagcgaaaa tcttatgatc gttggggcat
     5581 tgaaataact agttttaatc gaaatattgc ttttcacgtg gagtgtgact gtggggaatt
     5641 agcaaaaagt gtttatcaaa aaaattactt ttactgtcct aaatgccatc gccgata
//
LOCUS       DADQDV010000127         5497 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.131, whole genome shotgun sequence.
ACCESSION   DADQDV010000127 DADQDV010000000
VERSION     DADQDV010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5497)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5497)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5497
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.131"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..954
                     /locus_tag="J8S10_002890"
     CDS             <1..954
                     /locus_tag="J8S10_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631425.1"
                     /translation="STATPYQPNLLDDPYWLGKAPLGENIANKSVTFPIKSSAYSLYQ
                     ANMEEEFVLGQTYTITMKATKPPIQTFIVYNEDSGDYRYGNLEPVEGLVDTWGLTFTP
                     QKVGVNYPKRLTIIQYPQSTTGACQIDWLKIEKGDTRTPNISQFKYFGEGLKDSNNPN
                     DYSWDVTPEYTEKGLNDAVNVYDPQRVEGLKNFADGIQIAGDKVISENDCTVYTLTKD
                     NSQSFIDGYATFIKHGKEVIVNGTVKFKKAYAFGVPLDDEVPDEFVAKIVHGMLTGPS
                     GTSSVSKAMYVRKDLGTIITNSEFAANEWFTFHGNYWVGEE"
     gene            957..1403
                     /locus_tag="J8S10_002891"
     CDS             957..1403
                     /locus_tag="J8S10_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631426.1"
                     /translation="MKNIWKYGRTGGEYAGQVLDDMVMTVPFTDVPPLEGIRADGEPL
                     TIADQMFDPKLNQWIVLVNVLDHNDLNNLKAMYESLENENGDLKQLNAKLMLSDVAIK
                     QENTALKEKADGLAQINSKTMLASFQNSKDIAEIKEQLNPASKGGE"
     gene            1405..1542
                     /locus_tag="J8S10_002892"
     CDS             1405..1542
                     /locus_tag="J8S10_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HAZ9631427.1"
                     /translation="MFSFSDVKMMYDWGCFTDDQVRLFVPLCITDEEAEKIINKDKSA
                     S"
     gene            1579..1872
                     /locus_tag="J8S10_002893"
     CDS             1579..1872
                     /locus_tag="J8S10_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631428.1"
                     /translation="MINLGEWGTIAGSITAIVSLILLVIRPVTASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLVEHTQQIKTLFRERSR"
     gene            1895..2092
                     /locus_tag="J8S10_002894"
     CDS             1895..2092
                     /locus_tag="J8S10_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin"
                     /protein_id="HAZ9631429.1"
                     /translation="MILPDKYYQVIKWTVLTVLPAASVLVATLGKAYGWNGTDMTVLT
                     INAVATFLGVITGVSAYNLKK"
     gene            2103..3122
                     /locus_tag="J8S10_002895"
     CDS             2103..3122
                     /locus_tag="J8S10_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAZ9631430.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGPNEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSDDKPVIDPTRAGAAN
                     PTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVKADGIY
                     RPDVNQAYNTLGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYL
                     NIPQR"
     gene            3379..4026
                     /locus_tag="J8S10_002896"
     CDS             3379..4026
                     /locus_tag="J8S10_002896"
                     /inference="COORDINATES: protein motif:HMM:NF014505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAZ9631431.1"
                     /translation="MPNKNYRVYKRGTIVYVDFGVNVGYELSGNHFAIVLNNKDNSKN
                     GVVCVVPISSKKKSNYVSVGKILEVASIKQFISQADKLKEKLRIIILLSLNRGIIDES
                     DLNSFIKDIEAKGEKLSVEEVEKRAVKHNLVCETREQVIKEIKSLSEDMVKYQKVFNC
                     YKKYTQESYVMPLNIQTISKNRIRRINKFDPSGNMKAPGNVLNEVDESLKKYFTK"
     gene            4309..4382
                     /locus_tag="J8S10_002897"
     tRNA            4309..4382
                     /locus_tag="J8S10_002897"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4343..4345,aa:Ile,seq:cat)
     gene            4928..>5497
                     /locus_tag="J8S10_002898"
     CDS             4928..>5497
                     /locus_tag="J8S10_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HAZ9631432.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNG"
BASE COUNT         1946 a          866 c         1085 g         1600 t
ORIGIN      
        1 tcaacagcca ccccatatca gccaaactta cttgatgacc cttactggct aggtaaagcg
       61 cctttgggtg agaatattgc taataagtct gttacgtttc caatcaaatc tagcgcctac
      121 agcctatacc aagctaacat ggaagaagaa tttgttttag gtcaaaccta tacaattacc
      181 atgaaggcaa ccaaaccacc tatccaaacg ttcattgttt acaacgagga tagtggagat
      241 tatagatatg gtaacttaga gccagtagaa gggttagttg atacatgggg tctgactttt
      301 acaccgcaga aggttggagt taactacccc aaacggttaa ctattatcca gtatccccaa
      361 tcaacaacag gtgcatgtca aattgactgg ctcaagatcg aaaaaggcga cacacgaacc
      421 ccgaatatta gtcagtttaa atactttggt gaaggcttga aagacagtaa caatcccaat
      481 gattacagtt gggatgtcac acctgaatat actgaaaaag gcttgaatga tgctgttaat
      541 gtgtatgatc ctcagagagt tgaaggtttg aaaaactttg ccgatggtat tcaaatagca
      601 ggagataaag tgatcagtga aaatgattgc actgtttata cattaactaa agacaacagt
      661 caatcgttta tcgatgggta tgcaacattt attaaacacg gaaaagaagt tattgtaaat
      721 ggtacagtaa agttcaaaaa agcttatgct tttggtgtac cacttgatga tgaagtccca
      781 gatgaatttg tcgcaaaaat tgttcatggc atgcttacag gtccgtcagg aacaagtagt
      841 gtatcaaaag cgatgtacgt gcgaaaagac ttaggaacaa ttattacgaa tagcgaattt
      901 gctgcaaatg aatggtttac attccatggt aattattggg taggggagga ataaaaatga
      961 aaaatatttg gaaatacgga cgaacaggtg gagagtatgc tggacaagtg cttgatgata
     1021 tggttatgac tgttccattt accgatgttc caccactcga aggaattcgt gctgatgggg
     1081 aaccactaac gattgctgat cagatgtttg atcctaaact gaaccaatgg attgttttag
     1141 tgaatgtact agatcacaac gatttaaaca atctcaaagc gatgtatgag tcgttagaaa
     1201 atgagaacgg cgatttaaaa cagctcaacg ccaaactcat gctaagcgat gtagcgatta
     1261 aacaggaaaa tactgcattg aaagaaaaag cggatggttt agcacaaatc aattcaaaaa
     1321 cgatgcttgc ttcgttccaa aatagcaaag acattgcaga aattaaagag caactaaatc
     1381 cagcttcaaa gggaggtgag tagtatgttt agttttagcg atgtgaaaat gatgtatgat
     1441 tggggctgtt ttactgacga tcaagttcga ctattcgttc cactatgcat tacagacgaa
     1501 gaagcagaaa aaatcattaa taaagataag agcgcatctt aagtgatgcg tttttattta
     1561 aggtaaagga gttgtcacat gattaattta ggagaatggg gaacaatcgc aggatcaatc
     1621 actgcgattg tttctttgat tttattagta ataagaccag tcactgcatc tttctcgaag
     1681 attactgaaa ctctttcaaa agtaagtcac aatttagatt tgctgactaa agatttagaa
     1741 tcgagcaaat cagatcgatt gatgattcat gaagaactaa agaaacacga tgaaagatta
     1801 gatacacata cagaaaaatt ggtagaacac acacaacaaa tcaaaacttt atttagagaa
     1861 agatctcggt aaaaaagaaa ggagttaaga agaaatgatt ttacccgata agtattatca
     1921 agtcattaaa tggacagttt taacagtatt gccagctgca tctgtattag ttgcaacact
     1981 aggcaaagcg tatggatgga atggaacaga tatgacagta ctcactatca atgcagtagc
     2041 aacattttta ggcgttatca ctggcgtgtc ggcttataat ttgaaaaaat aggaggaaac
     2101 aaatgaaaaa gaaaattact attactgcga tgagcctatt aacggctctt tttttattgc
     2161 caattaatgg gtttgcctat acgattaaca atgaatttaa tttaggccca aacgaaggta
     2221 gctcacaagt agcaaataat cagtacattt tactgcatga aacggctaat gaaacagcaa
     2281 caggacgcaa tgaagcgcag tatatgcaac gttcatggac tagcgcttat actgcttata
     2341 ttgtgggaga cggcggaatt gtttatcaag tcggtcaacc tggttatgta cagtacggtg
     2401 ctggttcgta tgctaatgca aatagtcctg tgcagattga gttacaacac acacatgata
     2461 aagcaacgtt tgagaaaaac tacaaggcat acgttgaatt agctagagat tcagcaatga
     2521 aatatggtat tccacttaca ctagacacac cgtataatca accagggatc aaatcgcatt
     2581 tatgggtaac acaaaatatt tggggcgatc atacagatcc ttacggttat ctttctgaaa
     2641 tgggcgtaag taaagaaaaa ttagcctatg atttggctca tggatttacc gatgaaaatc
     2701 cgacaacttc agatgataaa ccagtcattg atccaactcg agcaggtgct gcaaatccta
     2761 ccctgacaga tggaacaaat tacgcccaca ttgatcagtt cggagaaatc gaaaacgcaa
     2821 acttacatgt ggctggttgg cacatcgcta actataaata cgagtatatc ttcattatgg
     2881 attacaatac tgggaaagaa ttagctcgag taaaagctga tggaatatat agaccagatg
     2941 taaatcaagc ttataatact ttaggaaatg ttggctatca tgtatctttt aacatgcgca
     3001 acttccctaa taagaaagtc tatgtaatga tgcgggcaac gaatgatcca gaagggaaca
     3061 ctaaaggcgg agcacaagat tttcatgata aacgctggta tttaaatatt ccgcaacgat
     3121 aaaaatagcc cctcgttttt gaggggaagt acataatgca aatttgtcca taacttattg
     3181 attatcttgt aaaaatgcgg taatttaata gttagtgaga agaggtgctt aattatagtt
     3241 aaaaaagagg aaatagaagc agcatgtaac caagcaaatg ttaggtttat tggagaagct
     3301 ttatctggat atcctaagta taaatactta cacaactggt tacaaagtaa aagtttttat
     3361 cttaataaag aaagatgcat gcctaataaa aattataggg tttataaaag aggaactatt
     3421 gtatatgttg attttggggt gaacgtgggt tatgagttat ctggtaatca ttttgctatt
     3481 gttttaaata ataaagataa ttcgaaaaat ggtgttgtat gtgtagtacc aatctcttca
     3541 aaaaagaaaa gtaattatgt atctgtagga aaaatattag aagttgctag tattaaacaa
     3601 tttataagcc aagctgataa attaaaagag aaacttagga taattatttt actttcatta
     3661 aatagaggca tcattgatga aagcgatttg aatagtttta ttaaagatat tgaagctaaa
     3721 ggtgaaaagc tttcagtgga agaagtagaa aaacgagctg taaaacataa tttggtttgc
     3781 gagacaaggg aacaagtaat taaagaaata aaatcattat ctgaagatat ggtaaaatat
     3841 cagaaggtgt ttaattgcta caagaaatat acacaagaat cctatgtaat gccacttaat
     3901 atccaaacga ttagtaaaaa tagaattaga agaattaaca agtttgatcc ttctggaaat
     3961 atgaaggcac ctggaaatgt cctcaatgaa gtagatgaaa gtttaaaaaa atattttaca
     4021 aagtaaacga tatttttgtt gacatttttc tgttcgttag ttaccatgta gttatagaag
     4081 gacgtaagcg cctattttta atgtacacat cgggacgtat gcgcccacat agaaacatag
     4141 ttgagagaca tctatatggt gtctcttttt ttattaatat gcaaaaaagt ctagtttttt
     4201 caataatatt tatgtaataa taaattagcc accacaacaa agaatgaaac ccattattat
     4261 ctagtctatg tccattcttt ttgtttgcag tagttgtgat ggctttccgt actcttagct
     4321 cagttggtta gagcagacgg ctcataaccg tccggtcgta ggctcgagtc ctacagggta
     4381 catactctaa gtgatttaaa ttgcgaataa aatataaaaa tgactcccct tttgactccc
     4441 ccaagcagta tatggatgtc tctaaaagtt gtttttttag ataataaaaa gctgataata
     4501 agcgaaaaac acttaaaatc agctttaaac cctattctcg aaatccggcg aaccggctaa
     4561 taccggcgcg caggttcaaa tcctgtacct tccttatatc aacgattaga ggttgtgaag
     4621 aagctgtcct gcatcaagta ataagaacgg ccaaacaaaa atagcttttc ctattttttc
     4681 gtttgattgg gcttattacc gcagatgcaa gcttttgaac accgtttgtt cggaataagg
     4741 ggctgtgaca agacttttgt cacagcccct tattgttgta cttttaacct acaatatttt
     4801 ttgattcccc ctgagtacta ttttttataa atgctagtaa atcaatcttc tttggccttt
     4861 ttttgataaa aaaaatacta gatgtaagat aaaagtgtaa aaacgatttg ttttaggagg
     4921 ggaaacgatg tgtaccgcaa tcacttatgc aacgaaagac cattattttg gaaggaattt
     4981 tgattatgag atgtcttata atgaagtggt cactattact ccaagaaatt atcgtttcga
     5041 ttttagaaag gtaaaaaatt tagataaaca ttatgcaatg ataggaatag cagctggggt
     5101 atccaactat ccactctatt atgaggctac aaatgaaaaa gggttgagta tggcaggact
     5161 gaattttcct ggcaatgctg attataaaga attacaagaa ggaaaagata acgttgcacc
     5221 atttgagttt attccatgga tactagggca atgctcaacc atagacgaag ctaaagaatt
     5281 attggctact atcaatctag tcaatatcga ttttagtgaa aaactaccct tgtcaccttt
     5341 acactggtta ttagctgata aagaaaaatc gatagtaatt gaaagtatga aagatggact
     5401 tcatttatat gataatcctg tcggtgtgtt gacaaataat ccgccatttg attatcaatt
     5461 atttaatctg aacaattatc gctcgctatc aaatgga
//
LOCUS       DADQDV010000128         5419 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.132, whole genome shotgun sequence.
ACCESSION   DADQDV010000128 DADQDV010000000
VERSION     DADQDV010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5419)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5419)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5419
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.132"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..1192
                     /locus_tag="J8S10_002899"
     CDS             <1..1192
                     /locus_tag="J8S10_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAZ9631433.1"
                     /translation="SDADKYNPEGQKVTTELNKEPDASEGIKNKEDLPKDTKYTWKEK
                     VDVSAAGNKKGTVVVTYPDGSSDEVEVDVTVTDNRSDADKYEPTVEGEKVEVGGTVDL
                     TDNVTNLPTLPEGTTVTDVTPDGTIDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDN
                     RSDADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKEKVDVSTAGNKKGIV
                     VVTYPDGSKEEVEVTISVEDKKAPNKPQVDPITEGDQIVTGKTEPNAEVTVTLPNGSQ
                     YHGTADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNVVVSSNEKDSEKAVSKDN
                     KTDNQGSKQNKNRGKSSPQKQSSKAYPKTGEIDSNIFTISGGLILLGTLGLLGYKNRK
                     KENE"
     gene            1326..2669
                     /locus_tag="J8S10_002900"
     CDS             1326..2669
                     /locus_tag="J8S10_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAZ9631434.1"
                     /translation="MKKIVIIGSNHSGLAAARFLNLCDSNYEVILIDKKSEISYLECG
                     TSLFIKREVSNLEDLFYQNRRELNSKIKKLFLETAVDKIDIQNKKIICVKKDGTRFSQ
                     EYDKLILATGSKQIMLDVPGNNLANIFSIKNFPNAKEIFKALDDNTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGKKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHIDNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPVFLRKNSRVKLRISFEKNTKRIVGVQL
                     CSQEDLSGLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFILKAVTGLNIET"
     gene            2781..4232
                     /locus_tag="J8S10_002901"
     CDS             2781..4232
                     /locus_tag="J8S10_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HAZ9631435.1"
                     /translation="MKKSLKLASAVILMSQLFIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTLSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTTSN
                     AESSTTSSSESSTISSAESSTTSSSTSEITSSKVTRPNHIESSKKEAPKTEGQTKNFS
                     TPQQIESTESFQSQPILSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIA
                     QAILESASGQSQLAQAPNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYEN
                     YEESFEDYAKLLTKGISGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNEL
                     IKTYDLTNYDKEVKGPQMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIH
                     AVKAGKVVKAEFHYSWGNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGST
                     GNSTGPHLHLEICKDSSLSQSMLVDPKTLLFGD"
     gene            4581..5252
                     /locus_tag="J8S10_002902"
     CDS             4581..5252
                     /locus_tag="J8S10_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HAZ9631436.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRYLCDCGNETIVYRSNLLSGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCQCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEKWIAYITLK
                     KRGTI"
BASE COUNT         2091 a          736 c         1037 g         1555 t
ORIGIN      
        1 atctgacgct gacaaatata atcctgaagg tcaaaaagtg actacagaat tgaataagga
       61 accagacgca tctgagggaa ttaagaacaa agaagattta ccaaaagata ctaagtatac
      121 ttggaaagaa aaagtagatg ttagcgcagc tggaaataaa aaagggactg ttgtagtgac
      181 atatccagat ggatcatctg atgaagttga agtagatgtt acagtgacag acaatcgttc
      241 tgacgccgat aaatatgagc caacagtaga aggcgaaaaa gtagaagttg gaggcacagt
      301 agatctaaca gataatgtta ctaacttgcc aacattacca gaaggaacaa cagtaacaga
      361 tgtcactcct gatggtacga ttgataccaa cacaccaggt aattacgaag gggttatcga
      421 agtaacgtat ccagatggta cgaaagatac agtgaaagtt ccagtagaag tgacagacaa
      481 tcgttccgat gccgataaat acaatcctga aggacaaaaa gtgactacag acttaaataa
      541 agagccagac gcatctgagg gaattaagaa caaagaagat ctaccaaaag gaactactta
      601 tacttggaaa gagaaagtag atgttagtac agctggaaac aaaaaaggga ttgtagtagt
      661 aacatatcca gatggatcta aagaagaagt agaggttact atttctgtag aagataaaaa
      721 agcaccgaat aaacctcaag ttgatcctat tacagagggt gaccaaattg ttactggtaa
      781 aactgaacca aatgcagagg tgacagttac attaccaaac gggagtcaat accatgggac
      841 agctgataaa aatggtaatt ttacagttaa agttcctaaa ttagaggcag gaacaaaagt
      901 gatagtaact gcaactgatg aatctggtaa tactagtgaa cctactaatg tagttgtttc
      961 ttcaaacgaa aaagacagtg aaaaagccgt tagtaaagat aataagactg acaatcaagg
     1021 tagcaagcaa aacaaaaata gaggcaaaag cagtcctcaa aagcagtcct caaaagctta
     1081 tcctaagacg ggagagattg atagtaatat ctttactatt agtggtggtt taatcctgtt
     1141 aggaacttta gggttattag ggtataaaaa tcgaaaaaaa gagaatgaat agaaaatcaa
     1201 tttcttaaat cttctctgaa aagaggaaga atctttttct tcctcttttt gttttttatt
     1261 ttgggagata ggttgttagt taaaaatgaa gatacttttc atagaaggga aaagaatgtg
     1321 attaagtgaa aaaaatagta attattggat caaaccattc ggggctagct gcagctcgat
     1381 ttctaaactt atgtgattca aattatgaag ttattctgat agataaaaaa tcagaaatta
     1441 gttacttaga atgtgggaca tcgttgttca taaaaagaga agttagcaat ttagaagatc
     1501 ttttttatca aaatagaaga gaactaaatt ctaagataaa aaagttgttt ttggagacag
     1561 cagttgacaa aattgatatt caaaataaaa agattatttg tgtaaaaaaa gatggcacaa
     1621 gattttccca agaatatgac aaacttatac tagctacagg ttcaaagcaa attatgttag
     1681 atgtaccggg gaataattta gctaatattt tttcgataaa gaattttcca aatgctaaag
     1741 agatttttaa agctttagat gataatacta ttaaaaaagt aggaattatt ggagcaggat
     1801 atattggagt tgaaattgct gaagccataa gaaaaagagg gaaagaagta tatcttttcg
     1861 atgttgcaga tagagtgttg tcgacttatt acgaccgtag tttttcagat aaagttgaag
     1921 aaatactatc aaaaaatgga atacatcttt gtctatcaga aagtcctaaa aaatatttag
     1981 gaagaaaaaa gattgaaaaa atagtcacta caagtggtac ccaatactct atggatatgg
     2041 tcgtacaagc tataggattt ctatctaata gtccaattgg caaaaaggaa ctcttgagag
     2101 atgttagtgg agcatatcta actaatgaat accagcaaac aaatataaaa gatatatatg
     2161 ctattgggga ttgtgctaca acttttttta cgtccattaa tagaagtagt gttgattttt
     2221 ctatttctaa tgctctaaga acagcttata ttgcaactca acatattgac aatcaagatt
     2281 ttacaccttc tggttcccaa tttacaaatg gcttttctat atttaattac aatttttacg
     2341 cagcaggttt gaatttaaaa acagcacgat tattaagtga gtctatagat tatatagaaa
     2401 tagaagattt cattagacct gtttttttga gaaaaaatag tcgtgtaaaa ttaagaatta
     2461 gctttgaaaa aaatacaaag agaatagtag gtgtacaact ttgtagtcaa gaagatttat
     2521 ctggactatt atcaatgttt tctcttgcta tagaagaaca aattacatta gacaaattga
     2581 aaatgttaga ttatttattt catcctagtt ttagccaacc ctataatttt attttaaagg
     2641 cagtaacagg attaaacatt gaaacataat cgttactaaa tgaaatcaag aaatatactg
     2701 tattactcaa ttcattgaaa atatttatca taatttttaa tagaaaacac tattaaagag
     2761 aaaaaagaga ggtaaatcaa atgaaaaaat ctttaaaact tgcatcagca gttatattaa
     2821 tgtcccaact ctttatagca acacctttcc atgtgttggc aagcgaaaat tcaacataca
     2881 aaattgcaaa agaaagaacc gagacgactg aaatgagtaa ttccgatgta acagcagaga
     2941 gtagtgaact tttgacaact ttatcaagtg aaagtagtac gacttcaaat gctgagtctt
     3001 caacaacttc atcaagtgaa agtagtacga cttcaaatgc cgagtcttca acaacttcgt
     3061 caagtgaaag tagtacgact tcaaatgccg agtcttcaac aacttcgtca agtgaaagta
     3121 gtacgatttc aagtgccgaa tcttcaacaa cttcaagtag tacaagtgaa ataacttctt
     3181 cgaaagtgac aagaccaaac catatagagt cttcaaaaaa ggaagcgcca aaaacggaag
     3241 gacaaacaaa aaatttttcg acaccacagc aaatagaatc aacagaatct ttccaatcac
     3301 aaccaatact atctggtaat gaagaaattc attttgacaa aaatgaatct gtagaaaatt
     3361 ttattatgaa aattggtgag tctgcgagaa aaattggtca gaaatatgat ttatatgctt
     3421 ctgttatgat tgcacaagcg atcttagaat ctgccagtgg tcaaagccag ttagctcagg
     3481 caccgaatta caatttattt gggataaaag gaacttataa tggaaacttt gtcattatgg
     3541 taacaaacga agatttgggt aatggaacgc tttatacgac ccaatcaaaa tttagagtgt
     3601 atgaaaacta tgaggaaagt tttgaagatt atgccaaatt attaactaag ggaattagtg
     3661 gaaataaaga tttttatgca ggagcattaa aagctaatag taaaacatat cgagaagcaa
     3721 ctaaattcct tacaggacgg tatgcaacag atacacaata ctatttgaag ctaaatgaat
     3781 taattaaaac ctatgattta accaactatg ataaagaagt taaaggtcca caaatgagta
     3841 agactggata ccaagtgcct attcataatt attcaataac cagtttgttt ggaaatcgtg
     3901 gaaatgaatt tcaccgagga cttgatatgg cagctacaca gggtgagccg attcatgcag
     3961 ttaaagctgg taaggttgtt aaagcagagt ttcactactc ttggggaaat tacgtggtga
     4021 tacaacacga agatggatca accgcgttat atgctcacca gcaacaatac ctagtaaaaa
     4081 ctggagataa tgttttgcaa ggacaaataa ttggctatgt aggaagtact gggaatagta
     4141 ctggcccaca ccttcatttg gaaatttgca aagatagtag tctttctcag agcatgttag
     4201 ttgatccgaa aaccttatta ttcggagact aaaaaaggta atcaatctga caaagtaaca
     4261 agaaaatggt tggattctta gacctttgat caggatattg agactggaat tgatatctcg
     4321 attacgatga gtttgacaaa taaaacaagt ccattatcga atatcgagtg tattattgcc
     4381 gtctttatgc tcatattttg agcaggtttt actagatgaa aacaatttat ctatcttgag
     4441 gatttcgtgt acgtatcgtt cagtcttgta ttataaatta gtcataaaat cagactaaga
     4501 aaaattgaaa atattttttt ctgatttatt aaaagttaat tgaaattata tggtacttct
     4561 ttcttgggag ggtaggtgca gtgaaggaaa gatatggtca ccttactgtt gttgaggaga
     4621 ttactcataa tggatataaa aaatatcgtt acctatgtga ctgtgggaat gaaacgattg
     4681 tatatcgatc aaacttacta tcaggtagaa ccaaaagttg tggatgtgga aattataaaa
     4741 ataggcataa atataaaaat ttgacaaata aaacttttgg taagttagtt gcaatcaagc
     4801 caactaaact gcgaagtgaa ggaactgttg tttgggaatg tcaatgtctg tgtgggagaa
     4861 aaaagttagt atcggcaaag cgacttctaa aaggtgatgt aaaaagctgt ggatgtttga
     4921 aatcaaaaaa gcatcacatt gaaaataaaa aattcggatt acttactgca aagtatcctt
     4981 tggacaataa ctgttcatgg aaaacaaaat gggtttgtca atgtgagtgt ggcagtatgt
     5041 gtgagataag ttatagtaac ttattttttg gacatactca aagttgtgga tgtttaaaaa
     5101 ggcaagaaac aaggacatgt gttgaaggga cagtaataga gtgtctaacg tcaaaattac
     5161 cgaaaaataa tacaagtggt gttaagggag tttatcgttc taaagagaaa tggattgcgt
     5221 atataacttt aaaaaaaaga ggtactattt aggatcgtat gattctatta agagtgcagc
     5281 tcaagttaga aaagatgctg aaaataaatt gtttcaacct ttgattgaca aatatcgagg
     5341 taatcattaa ttattgtgga taataattaa cagtgatata taaacatcta taatatatta
     5401 ttcatactat tgacattta
//
LOCUS       DADQDV010000129         5339 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.133, whole genome shotgun sequence.
ACCESSION   DADQDV010000129 DADQDV010000000
VERSION     DADQDV010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5339)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5339)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5339
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.133"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(19..414)
                     /locus_tag="J8S10_002903"
     CDS             complement(19..414)
                     /locus_tag="J8S10_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008688205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631437.1"
                     /translation="MKNKGQIWYIGYIVSLFLIVTILVTDFPKMVDIGLAILFSAVFG
                     VSHVQILHDKMIKNDADYKINVMDERNIIIKEKAGNITNMFNTILLGVATVIFICLDY
                     IIPAIIVGSIIAIQPIILIIISSVLEKKM"
     gene            complement(404..616)
                     /locus_tag="J8S10_002904"
     CDS             complement(404..616)
                     /locus_tag="J8S10_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005814946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAZ9631438.1"
                     /translation="MKNRLEELRKQRGIKQEDLASALEVSRQTIGSLENGRYNPSIIL
                     AFKIARYFQMSIEEIFIYEEESEDEK"
     gene            1688..2290
                     /locus_tag="J8S10_002905"
     CDS             1688..2290
                     /locus_tag="J8S10_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631439.1"
                     /translation="MEDIILRDRLTDPLKNSLANVIYDILREADKVYSNYNGKVSWVI
                     YSFLIKEFFKEQINNSYELGYHFTVYYEDIIKRLEDLEWYAYYDLLEVFASAKILDKK
                     KREEVNKILESENSGYRLSESNEFIPITDDISIKSINAVSESPFNYAKNHIHKSLTYI
                     SEKENQDYNTVVREAISAVESCLIEFSGLPANKKILWELL"
     gene            2645..2881
                     /locus_tag="J8S10_002906"
     CDS             2645..2881
                     /locus_tag="J8S10_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003125429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
                     /protein_id="HAZ9631440.1"
                     /translation="MNIKKRKIREVGNSIVVTLSKESLLQKGLKPGDTIFIDEDKMME
                     AIVKEESKIDLEIDMYVNQALSEYDAAFKELVEK"
     gene            2878..3291
                     /locus_tag="J8S10_002907"
     CDS             2878..3291
                     /locus_tag="J8S10_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HAZ9631441.1"
                     /translation="MIYLSEKDIVKLNVIQIKKYSPRETIGVIDKNALSMAVNQPKQH
                     IFGKDLYPDKFSKAAVLLINLIKKHPFHNANKRTAFLAAYVFLKLNGYSLKMKNQEVV
                     EFVVEIATYQGDFDDLKEATTDILKKNSTKTDSKK"
     gene            3810..4760
                     /locus_tag="J8S10_002908"
     CDS             3810..4760
                     /locus_tag="J8S10_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toll/interleukin-1 receptor domain-containing
                     protein"
                     /protein_id="HAZ9631442.1"
                     /translation="MERNSENKMTGRNPKVFISYSWENKENKEWARELADKLLENGID
                     AYIDQYDLSLGDRLPQFMEQQISDSDYVLIICTPEYKKKANNRTSGVGYEGHIISAEL
                     LSGKNERKFIPIIKEGRASEVLPTFLAGKLGIDLSDSQHYDENLDDLITTIFGVKRKP
                     ALGDIPRHIKGSPLLPIEHNENKDIEILGIITDKVTVPKMDGSRGSALYKIPFRLNRV
                     PSQLWKELFVRNWNSPPRYTTMHRPGIASVVDDEILLNGTTIEEVREYHRETLKLCIE
                     KSNTQEKKILLEEEQKKERENERVRSHKESVQKLADELEF"
     gene            complement(4757..>5339)
                     /locus_tag="J8S10_002909"
     CDS             complement(4757..>5339)
                     /locus_tag="J8S10_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAZ9631443.1"
                     /translation="SIDQNEQRQIEEMRKFGAEKIFIEKQSGATITHRPIFQEVLDFV
                     RDQDIFIVEAIDRLGRNYDEIIDSVNYLKKKNVRLIITNLPIMAEAIGNPLLDKFIKD
                     LIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANTKDPQRRLVYRSIV
                     QDQENGVAISKIATDYNVTRQTVYRIKKELTIN"
BASE COUNT         1908 a          760 c          902 g         1769 t
ORIGIN      
        1 ttgtatgaac ctttatttct acattttttt ctcaagcaca ctactgataa tgattaaaat
       61 aatcggctgg attgcaatga tacttccgac aataatagct ggaatgatgt agtctaaaca
      121 aataaatata actgttgcca cccctaacag tattgtgtta aacatatttg ttatatttcc
      181 cgctttttct ttgattatga tattccgttc gtccataaca ttgattttgt agtctgcatc
      241 atttttaatc attttatcat gcaaaatttg aacatgagaa acgccaaaaa cggcactgaa
      301 taaaatagca agtccaatat ctaccatttt aggaaaatct gtaaccaaaa ttgtcacaat
      361 caaaaacaac gaaacaatat aaccgatata ccaaatctga cccttatttt tcatcttcac
      421 tttcctcctc atagataaaa atttcttcaa tgctcatttg aaagtacctt gcaattttaa
      481 atgccaatat aatagaggga ttataacgtc cattttctaa agaacctatt gtttgacgag
      541 atacttcaag agcagaagct aaatcttctt gtttaattcc tctttgtttt cgtaattctt
      601 ccaaacgatt tttcacaaca tgctcctttc taaaaaatgg aaagtttact ttcctttcgt
      661 gcttttataa tactcctgcg agcacaaaat gtcaaggaag ctttccatat aaattttgat
      721 tttaatgttt tagttactgt ttttatgaca catgaacaca cttattctta tttcctctta
      781 tctgctatca acagaaaaga aaaagccctg tcaagagccg attagatcaa gccagtcgag
      841 aaacgatgtt agaccaaatt gattttgggt aatgaatgtt tagaacttag tagtcatcca
      901 aaaacgacta ctttttttgt tgaatcgtcc aaggacgatt cgatgctttt gacttgtaag
      961 aacaggattg aatgaaacca tactgttcgc atatttttag tggatgaaca aacaaaatac
     1021 gagagatttt ttgttcgttc atccatggtt ttagaaaaaa gagggacgat tttggaagaa
     1081 gaaaatcgtc tctttttttt cttctttttg tatgacaaaa agaaagatct tttgcccatt
     1141 ttatttttat aaaatgggta ggtggcgttc gcgtaaagca aatcgataca atccaatggt
     1201 tttggcgaat cagatttacc attctaggct tgtttaatac agacatcgat tgttattttg
     1261 agaatttata tccttattgg caatgaaatg gatattctcc ataccaatag aaatcttcaa
     1321 gataattttc ggaaatatat aagagttaat caattatgat catatagtag gtaaaaatta
     1381 ggacagcctt caattatatg ggaaaccaat ataatcaagt aattattcgg gtaacacaaa
     1441 tactagagta ctcatttctt ataactgttt tacacctatt agggatcagt attattaata
     1501 gatctagata aattaatacg taattatata ataatttatg tttgtgccat taaacaatct
     1561 taacagatat ttcattttat ttatgtaaaa caacacgaat aattattgct tcgtaaagtt
     1621 atatgagtat aagttaattt actggaggta gtgcaatgct tttttctgaa agatttggtt
     1681 ttaaaaaatg gaggatatca tactgagaga tagattgaca gaccctctta aaaatagttt
     1741 agcaaatgtg atttatgata tattacgaga ggctgataaa gtttatagta attataatgg
     1801 aaaagtctca tgggtaatat attctttttt aattaaagag ttttttaaag aacagataaa
     1861 taatagctat gagttgggtt atcattttac tgtttattat gaagatatta tcaagaggtt
     1921 agaagacttg gagtggtatg cttattatga tttattagag gtttttgcaa gtgctaaaat
     1981 cttggataaa aagaaaagag aggaagtaaa taaaattctg gagtcggaaa attctggtta
     2041 cagattaagc gaaagcaatg aatttattcc aatcacagat gatatttcta ttaagtctat
     2101 aaatgctgta tctgaatcac catttaatta cgcaaaaaat catatccata aatctcttac
     2161 atatataagc gagaaggaaa atcaagatta taatactgta gtgagagaag caattagtgc
     2221 tgtcgaaagt tgtcttatcg aattttcagg attaccagct aataaaaaaa tactttggga
     2281 actgctataa aagcaattaa agacaaatcg aataacaatg tcgatcttac atttttaaaa
     2341 ccatttgaga caatgtatgg tttggcgagt aataatggaa tacgacatgc agaaaatgaa
     2401 aaaacaattg tctcagattt acctgatgca gttttggtgt taacaacatg ttcagccgta
     2461 attaattatt tgggagtaaa aatagcatat gactccaata aatcatgaaa agttaaaatt
     2521 catccaagag ctacattata actattaatt tccaactctt taaaagttta gtaattgaag
     2581 gaagtaataa gggtgattga acaatacgga tatacggtgt atacttatcg taggagttga
     2641 tgatatgaat attaaaaaac gcaaaatcag agaagtaggt aattcaatag ttgtaacttt
     2701 gtcaaaagag agtttattgc aaaaaggttt gaaacctgga gatactattt ttattgatga
     2761 agataaaatg atggaagcta ttgtaaaaga ggaaagcaag atagatcttg aaattgatat
     2821 gtatgttaac caagctttat ctgagtatga tgcagctttc aaggaattag ttgaaaaatg
     2881 atctatctaa gtgaaaaaga tattgtaaaa ttgaatgtta ttcaaataaa gaaatattca
     2941 ccgcgagaaa caatcggagt cattgacaaa aatgcgctga gtatggctgt aaatcaacct
     3001 aaacagcata tttttggaaa agatctgtat cctgataaat ttagcaaagc agctgttctg
     3061 ctaataaatc tgatcaaaaa gcatccattt cataatgcta acaaacgtac agcattttta
     3121 gccgcgtatg tttttctcaa gctaaatggc tattcactaa aaatgaaaaa tcaggaagta
     3181 gtagaatttg tagttgaaat tgctacgtat cagggtgatt ttgatgactt aaaagaggca
     3241 acaacagata tactaaaaaa gaattcaaca aagaccgatt caaaaaagta gaagcaaact
     3301 agggattcag ttaaatctga agatttagtt tgttctttat tttagtttac ataagataca
     3361 ttatgcgaag ttcattattt taaaagctta aataataaac ttttttataa taccaattta
     3421 tttatgtaaa ccaatgacct taatcgctta agcaagcatg ttatgtaata ctctactctc
     3481 tccaaaacta atgactatct attttcaaag aagctagaat gattatctga tcaaatgata
     3541 atttatattt aattcctggt ctactgctct tcttttaatc aattaatgtc taacgtactg
     3601 tacacgataa agtaggaaga cttattttca acttcggatt cattttttta attcggtgaa
     3661 aatcactaaa ttaagagttt atccaagttc attttagctg agaatacgct tgaaaataat
     3721 tttgatgaat tttcctgaat taaaatttat taacttgttg agtgatataa ttgtaatgta
     3781 ttaccaaata gttagcactt agattagtga tggaaaggaa tagtgagaac aagatgactg
     3841 gtagaaatcc caaagtattt atatcatatt catgggagaa taaggaaaat aaagaatggg
     3901 ctagagaact agcagacaaa ttacttgaaa acggtattga tgcatatata gatcagtatg
     3961 atttaagttt aggtgataga ttacctcagt ttatggagca gcaaatatcc gattcagatt
     4021 atgttctaat tatatgtaca ccagagtata aaaaaaaggc aaataatcgt acaagtggtg
     4081 ttgggtatga aggtcatatt atctcagcag aattgctttc tggaaaaaat gaacgtaaat
     4141 ttatcccaat aattaaagaa ggacgtgcaa gcgaagtact tcctactttt cttgctggaa
     4201 agcttggaat tgatttatca gatagccagc attatgatga aaacttagat gatttaatta
     4261 caactatatt tggtgttaag agaaaaccag cattaggtga tatacctagg catattaaag
     4321 gcagtccttt actacctata gaacataatg aaaataaaga tattgaaatc ttaggaatta
     4381 tcactgataa agtaactgta cctaaaatgg atggctcaag gggttctgca ttatataaaa
     4441 ttccatttag attaaataga gtaccaagtc agctttggaa agagttgttt gttagaaatt
     4501 ggaattcacc accacgatat acaacaatgc atagaccagg aattgcttct gttgtagacg
     4561 atgaaatttt acttaatgga acaactattg aggaagtccg ggaatatcat cgggaaactt
     4621 taaaactttg cattgaaaaa agtaatactc aagaaaaaaa aatattgcta gaggaggaac
     4681 aaaaaaaaga gagagagaat gagcgagtca gatcacataa agaaagtgtt cagaaattag
     4741 cagatgaatt agagttctag ttgatagtca gttctttctt aattcgatac acagtttgtc
     4801 tagttacatt atagtctgtt gctatttttg aaatagcaac accattctcc tggtcctgaa
     4861 cgatgcttct ataaacaagg cgacgttgag gatcttttgt gttcgcactg tataacttag
     4921 gacgtccttt atagacgccg tttgctttag caatctttat cccttgtgcc tggcgtcgtt
     4981 ttgattcagt acgctcttgt tcagcaatca tggccaagat ttgaatgatt aggtctttga
     5041 taaatttatc caggagagga tttccgattg cttcagccat gatcggtaaa ttagtgataa
     5101 taagtcgcac atttttcttc tttagataat ttactgaatc gataatctcg tcataattac
     5161 gtccaagtcg atcgatagcc tctacaataa aaatatcttg gtctctaaca aaatctagaa
     5221 cttcctgaaa aatcggtcga tgagtaatag tcgctccaga ttgtttctcg atgaaaattt
     5281 tttcagcacc aaattttctc atttcctcga tttgacgttg ttcattttga tcgatcgat
//
LOCUS       DADQDV010000130         5311 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.134, whole genome shotgun sequence.
ACCESSION   DADQDV010000130 DADQDV010000000
VERSION     DADQDV010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5311
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.134"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(73..1221)
                     /gene="nagA"
                     /locus_tag="J8S10_002910"
     CDS             complement(73..1221)
                     /gene="nagA"
                     /locus_tag="J8S10_002910"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HAZ9631444.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(1297..2133)
                     /locus_tag="J8S10_002911"
     CDS             complement(1297..2133)
                     /locus_tag="J8S10_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAZ9631445.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(2317..3534)
                     /locus_tag="J8S10_002912"
     CDS             complement(2317..3534)
                     /locus_tag="J8S10_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAZ9631446.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            3917..4000
                     /locus_tag="J8S10_002913"
     tRNA            3917..4000
                     /locus_tag="J8S10_002913"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3951..3953,aa:Leu,seq:gag)
     gene            complement(4240..5237)
                     /locus_tag="J8S10_002914"
                     /pseudo
     CDS             complement(4240..5237)
                     /locus_tag="J8S10_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321168.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1653 a         1082 c          838 g         1738 t
ORIGIN      
        1 ttttactaga acacaaaaaa aaccttaaaa ccaaacttaa gaagtttagt tttaaggtta
       61 acttaaatta tattatgcgt ggaaacgttc cacgccatct agataagttg cttccaatgt
      121 catatcaggg ttcaatacga taaagtctgc atcgcgtcct tgagcgattt ttccacatgt
      181 atcatcgatt ttacagctga ttgctggaat cagactagcc atcatgactg cttgttctgg
      241 tgttgctaat ccccagtcta caacattttt aattgcttct ttcaatttca atatacttcc
      301 agctaagttg ccagattcta gacgtgctgt tccttctttt actactactg gaaattcgcc
      361 taaattgtaa tttccatcag gcatcccacc ggccatcata cagtctgtaa ttaatgcgac
      421 atgatcatgt cctgcttttt ccattaggat tcccgcagca tttggatgta catgatggcc
      481 atcacaaatc aattcagaaa agacatgttc taaagataat aacgcaccca ccatacctgg
      541 ttcgcgatga ttcaatccac gcataccatt gaaagcatgg acaaatacac ttgcgcctgc
      601 ttcaacagct ttttgcgctt cttctagtgt agcattactg tgtcctagag aaacaactac
      661 tccttcttca gtcacttgtt tgacaaactc ttctacacct tgacgttccg gtgctaaagc
      721 aatttttttg attaaaccac ctgaagcttc ttgccattca tggaaagtat ccaaatcagg
      781 atccccgaaa taacttgggt tttgtgcccc tttgtgttct tctgtgaaga aaggaccttc
      841 aaaatagatt cctttgattt tagctcctgg tgcttcctga tacattttgc cgattgtctc
      901 agctacatct tttaaacgtt ctttgcttga cgtcaatgtt gttggtaaaa atgaagtcac
      961 tccacaagat aacagacctt cagacatcac tttgatgcct tctgcatcat tatccattac
     1021 atcatgattc atatagccgt gaatatgtgt atctaccaaa ccaggagcaa tccatttgcc
     1081 gctttggtca atgatgttga cttctccctc aggtagttct ttggtgtatt caccaaaaag
     1141 tccatcggta atttcaagat agcctgcatg tttgacacct gacgctaaaa agaatttgtc
     1201 agcatagata aaagttctca ttctattctc tccctttgtt tttctacctc taaagtactc
     1261 ttatttagag aagaagtcaa gaatggtcta caccatttac aaattttttg aaatttgttt
     1321 cacagcttgt gctaagcctt catagaatgc tgctctttct ggttcttctt tacgcttgta
     1381 tattaagctt ttaagcacaa ataaatcatt gaggtaatag tagctattct tctcttgagc
     1441 ccaatagatt ccttgattca cctgttctaa cgcttcgtcg atttcatttt gatggaataa
     1501 gaaatttcca taattataaa aaatttgcga aaattcactt tttgatcgtt catcagctga
     1561 ttgatgcagc agttggatgc ttcgactcaa atagtagcgt gcttcagccg tttttcctgc
     1621 cacaccatat atttttccga tacaactaat cagttgtatt tctgtgtcag aaacatggat
     1681 tctttctttt tggctagagt agcttaatgc ttctttcaaa taataaaggg actgagagat
     1741 attttgacgc aacgtgaatt cgcaaacacc gagataataa taatagcgtt gaaagtcagt
     1801 tgcttgatac agattttcag aaatatcaga agattttagt acttgttcta acttccgata
     1861 atcacgtttt tggaaacaac tatccaacag ttcaaataat ttatcgtttg tccgagtagt
     1921 ttttcgagag agattcatca catgatcaat cgttacccct agccgttgac aaatctgcat
     1981 catcaccaat acattcggca gttcctcatt attttcgatc cgacttaata cactttgtga
     2041 acaaatatca tgcgaaagca ttttttgcgt cattttttgt tcttttcgaa tctctttaat
     2101 gatcgttcca aaggactcga ttaacgtttc cataagtatc ctccccaaaa tatgcgtatt
     2161 cgcattctat tcgtatttta ctttaggaag tcgcaaactt caagaaaaga cttgcaacta
     2221 aataatatac tttagttatt taagaaaact ccactagaaa gagagcctca gtgtgtttgt
     2281 ctgtggccct cctactgaaa aatttggttt ttaaaatcat ttttggcgat aggttgctag
     2341 gaattctctc attttcttag ctgtttgttt caaatcatcc attttaggaa gataaacgat
     2401 tcgaaaatga tctggctggt tccaattaaa tccaccacca tgtacaagta gaatatgatg
     2461 ttcatgtaaa aagtccaaaa cgaatttttc atcatccaaa atattgaatc gctttgtatc
     2521 aatttttggg aatatataaa aagcagcttt tggttttacg gctgaaagac caggaatatc
     2581 attgattgca ttatagatat attctctttg ttcatagatc cttccgcctg gcaggagcag
     2641 ctcatcgaca ctttgataac cgcctagcgc ggtttggata atttgctgag acaatacatt
     2701 ggaacacaaa cgcatggagg acaacatatt cagcccttct atatagcctt tgacgtgtga
     2761 cttatctcca cttaggacca tccagcctac tcgaaatcct gctacacgat gagatttgga
     2821 tagaccgttc agcgtaacaa cgaacaaatc aggcgctaat gtagcaatcg gaatatgttc
     2881 tagaccatcc atcactaagc gatcatagat ttcgtcggaa taaataatca ggttattttg
     2941 tcgagctact tcaacgattt cttctaataa ttcttttgga taaagtgccc cagtaggatt
     3001 attaggatta atgataacaa tagcttttgt ccgactcgtt atttttgatt tgatatcatc
     3061 aatatcagga taccattctg cctcttcatc gcaaatataa tgaacaggtg tgcctccagc
     3121 taatgcaata gaagccgtcc acaacggata gtccggcatt ggaaccagta cttcatctcc
     3181 attgtccagc aacccctgca tacacatcgt gatcaattcg ctcactccgt tgccggtgta
     3241 gatatcattg atcgtcacat tcggaaaatg tttcagttgg caatattgct caattgcttt
     3301 tctagcagaa aagatcccct tggaatctga gtagccttct gagtcacggg cattcatgat
     3361 caaatcacga atgacttcgt ttggtgcttc aaatccaaaa ggtgcgggat ttcccgtgtt
     3421 caattttaaa atactaatgc cctcttcttg catccgctcc gcttcttcta gaacgggacc
     3481 gcgaacatcg taactgacac cttctaattt gttggatttt tcaaattctc tcatcactta
     3541 gccaatccct catttcaaaa agttagaact ttccaaattt tttgttattt actatttcaa
     3601 tatcatactc catcctagaa aattttgcca cttatttagg aaaaacgtaa gtattaaaaa
     3661 aacacaaaca agcgttgaga acttaattgt catgatagtc attccataga ttcgctgccc
     3721 aatccattgc aattccacaa atgattccta gcataaaacc aagcaaaaaa cgtccgaatg
     3781 caagtccaat caatacacct aagatcattc ccagtcctga aaattctccg tcatatttct
     3841 ccatcttaat aagtcctccc atttttgagc ttgacaacta tgtaaaacct cgctatcatt
     3901 agtgtgttat tattacgcag atgtgttgga attggcagac aagcatgatt gagggtcatg
     3961 tgagcgttag ctcgtgtggg ttcgagtccc atcatctgca ctacaactcg tgaagttaat
     4021 tttgcttcac gagttttttt gtttgaacgt ttctttatgc cattatatac atatcactgt
     4081 atcctttaca aaaagaacgt acaatcatgt aaacagcctg aggtgagtat atgaaggtcg
     4141 gaaacaagct actcgtagaa acttgcaagt gttaaaacaa ttaatcgaaa aacgagtaaa
     4201 atccctcacc taatactaaa gcgagggatt ttttgtatat tatctgttta tcaccgttat
     4261 tataaaggta caaataccaa gcacggttaa tccaaattgc ataaattcat ttttttgtac
     4321 actcatgctt ttcattagct ctttaactgc cattagtact aagatggcga taacaacata
     4381 aagtatatag tacgtccgca ttccggaagc ccatactgtg ggagaaaatc ccataattaa
     4441 ccttgaacaa aatcccatta tcatcaaaat aactaaaaaa atagaagttt tcttattgtc
     4501 aaaacttaaa taaattccaa caattaaaca tagtaataat gccaagacta ctaaagtagc
     4561 tatccaagta cctggataaa aaagtgacag tttcgttcct aactctgtaa agagattatt
     4621 caggttacta ctactccaaa tcattgccct tttatttcca ttgacgtaag taaagctttg
     4681 acccattgta ttaccaaaat aaataatcag gtttaagaaa aacggtaatg cagtcaatat
     4741 acgcacataa tagttttgac atttcctata tgttagaagg aaaattaaga aaaatagcaa
     4801 taaaaataag atattcatgt ctaaaaaaac ggctttccaa atgatgaaat acctaaatct
     4861 aacttattaa gaaagttgaa atttttatat tcaggaaacc atttattaat ttcatgtgca
     4921 gcacgtaatg cattccctgg agttgtcaaa gagaaaatta attctgctaa gcttattatt
     4981 gaaaatactg ataacttata attatatcgt ccattgacaa tcaaatataa actaactata
     5041 cttgttagaa caaaaaaaca ggcgttgact tgttcttgat tagttaaaaa tatcaataaa
     5101 ggaatactta cccaatatat ttttctattt atttcttctc ctcttaagag ttgaaaaaac
     5161 ggataaaaag ttagtaaact aaatgctact ggccactgat agttcaaggt ggttgctctc
     5221 caaccggttt cccccattac tgtcaatggt attaaacagt atatagagca aaccaataat
     5281 aaatttttaa catttatttt ctcaaaaaca t
//
LOCUS       DADQDV010000131         5278 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.135, whole genome shotgun sequence.
ACCESSION   DADQDV010000131 DADQDV010000000
VERSION     DADQDV010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5278)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5278)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5278
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.135"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..104
                     /locus_tag="J8S10_002915"
     CDS             <1..104
                     /locus_tag="J8S10_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phosphosugar isomerase"
                     /protein_id="HAZ9631447.1"
                     /translation="FVITAVFRVYAEELSEAREHPLTKRRYMWKLTY"
     gene            220..2943
                     /locus_tag="J8S10_002916"
     CDS             220..2943
                     /locus_tag="J8S10_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAZ9631448.1"
                     /translation="MQRLNDYLYQLTLLLKSTPSDNYSARSISQALQLNRSTISSYLN
                     EGVREGLFIKVKSYPVLFLHRTALEELHITLNNSEIESIESLLTISQKPALDQVIGSK
                     GSLKEAIDQIKTAVLYPGKGLPLLLIGASGSGKTFLANKIYEYAVEEKVIHTSAPFID
                     YNCAQYVSNPELLSSALFGYTKGAFTGASQEHTGLLEKADGGVLFLDEVHRLSEEGQE
                     KLFTFMDTGEFSPMGDNSIRKKADVRLVFATTENIYTTFLPTFLRRLPVIVNLPRFQQ
                     RPSFERLSLIDEFFVSESKILAKELSVSDALIHFLMNSDFEGNVGNIKNIIKYACGNA
                     YIHQKSQQTIQVKLLDMPLEYSYKFKEQLNKPRKKRADRIYYPEETRQVQLERNNQLF
                     VQFFDQLLTGFSEVIENNKDIKLFLEEMVTKVTQVMDTLIFQEDYEKEQSLYAILNYH
                     IRQSIDFMRESYGFEQDGNRVVALANYLYVKDNQVIFENSLQEKKTKDQLNEFFANVL
                     ETPYWYAKKILSLLSECLDQPVYEEDIFFITLYFYSLNVTNVKTGIKSIVLAHGYSTA
                     SSMANVANRMLNKNVFQAYDMPLDITLEKIEAKLIQFLGDYRTDSGLILLVDMGSLNQ
                     LGGLLVNHLNGPLLIIDHINTPLLLEVGQQVLNNKSITEIGAEIETSLTFKKQLLLPK
                     KKKKKAIITCCYTGIGSATQIQEILTKCLKDAVRELVIIPYDYKKLLENKNFETPFQL
                     YDVIMIVGTEDPKINQIPYIGLDRLINGEAIGEFVHYLEKELTIEVNDLQKELIFNFS
                     ISKIVENLTILDPDKVLSFVQKAIKELSKLLNFDFSNNQLFLLYLHCSCMIERIVRKE
                     SVDEQEDIEEYMQANGEIMDKIHSAFFEIEREYTIEIPDLELRLLSDIVQG"
     gene            2956..3588
                     /locus_tag="J8S10_002917"
     CDS             2956..3588
                     /locus_tag="J8S10_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAZ9631449.1"
                     /translation="MTMGVIFDMDGVLIDSETFYFERRMNFFQELEIDPGSNQIDDYV
                     GKTEAAIWETLVPEDKSLREELYPKYVDYRKTHPIDFAKDLRKEVKPLLDFLKKRDIP
                     LALASSSPVVEIESMLIQCELTEYFSFVISGESLKQSKPHPEIYLKAKQQLDCDFFIA
                     VEDSTIGIKSAKAANIYTVALKQPMQIDQSEADIQIESLQELEQIVLEKG"
     gene            4487..>5278
                     /locus_tag="J8S10_002918"
     CDS             4487..>5278
                     /locus_tag="J8S10_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAZ9631450.1"
                     /translation="MKNLQLKFIVDPSIVRWFRIINQFERNQLATKGELAKSNHVSER
                     TIQTDVNKMKDYFSESVQFVSTKSGYSFQKERPVLFLKQKEQLLENEILFELLGNVFY
                     GELEDMTELIDRFHLSEATFRRYLKQIQPVLEEYGLELSLYPLDLKGEEANIRKFFKD
                     FYYEGEMTPHTLVPPRDLHELVQATFYDKFEYFSIGTGTSPAEFYYSLYIAIERVRQG
                     KTIAIPQGLIERVIASENFRLMYSLKEAIQTNYQVALSEEEFCWLY"
BASE COUNT         1803 a          801 c         1020 g         1654 t
ORIGIN      
        1 cattcgtgat tactgcagta tttagagttt atgcagaaga attgtcagaa gcaagagaac
       61 atccattaac taagagacgt tatatgtgga aactaactta ttaaaaaata gatcaaacta
      121 aataaggtgg cttgagaaat taagccacct tgttttcttc aatgtgattt tatacatatg
      181 gtaaaataac tagtacatat tgtgaaagca ggtggcaaga tgcagcgatt aaatgactat
      241 ctttatcaac taacattgct tttgaaatct acgccttcag ataattattc agctcgcagt
      301 atttcgcaag ctttacagtt gaatagaagt acaatcagta gctacttaaa tgaaggtgtt
      361 cgtgaagggc ttttcataaa agtaaaaagt tacccggttt tatttttaca tagaacagct
      421 cttgaagaac tacatatcac actgaataac tccgaaatag aatcaattga aagcttgtta
      481 acaatttctc aaaaacccgc attagatcaa gtaattggct ctaaaggaag tttgaaagaa
      541 gcaattgatc aaattaaaac ggcagtctta tatcctggaa aagggttgcc tttattattg
      601 atcggcgcta gtggatcagg gaaaaccttt ctagcgaata aaatatatga atatgcagta
      661 gaagaaaagg tcattcacac atcggcacct ttcatagatt ataattgtgc acaatatgtg
      721 agcaatccag agttactatc ctctgcttta tttggctaca cgaaaggagc atttaccgga
      781 gcaagccagg agcatactgg tttgctagaa aaagccgatg gaggagtatt gtttttagat
      841 gaagtgcatc gcttatctga agaagggcaa gagaaattat ttacatttat ggatacgggt
      901 gaattctctc ctatggggga taatagtatt cggaaaaaag ccgatgttcg attagtcttt
      961 gcaacaacag aaaatatata tacgactttc ttaccaactt ttcttaggag attgccagtt
     1021 attgttaatc tacctagatt tcaacaacgt ccgtcgtttg aacgtctgtc attgattgat
     1081 gaattttttg tttctgagag taaaatttta gctaaggaac tatctgtttc tgatgcattg
     1141 attcatttct taatgaatag tgattttgaa ggtaacgtgg ggaatattaa aaatattatc
     1201 aagtatgctt gcggaaacgc atatatccac cagaagagtc agcaaacaat tcaagttaaa
     1261 ttattggata tgcctttaga gtacagttat aaattcaagg agcaactaaa taaacccaga
     1321 aagaaaagag cagatcgaat ctactatcca gaagaaacac gacaagtgca actagaaaga
     1381 aacaatcagc tttttgttca attttttgac caattactta ctggattctc tgaagtgatt
     1441 gaaaataaca aggatattaa actattttta gaagaaatgg ttaccaaggt aacacaagta
     1501 atggatacgc ttatttttca agaggattac gaaaaagagc agtctttata cgccattcta
     1561 aactatcata ttcgtcaaag tattgatttt atgcgagaaa gctacgggtt tgaacaagat
     1621 ggtaaccggg tagtcgcttt ggccaactat ctatatgtca aggataatca agtgattttt
     1681 gaaaatagtc ttcaagaaaa gaaaaccaaa gatcagctta acgaattttt tgctaatgtt
     1741 cttgaaaccc cttattggta tgcaaaaaaa atcttaagcc ttttatctga gtgtttagat
     1801 caacctgtgt atgaagagga cattttcttt attacgctat atttttatag tttgaatgtc
     1861 acgaatgtta aaacaggtat taagagtatt gtgctagctc atggttattc tacagctagt
     1921 agtatggcga atgttgccaa ccgtatgctg aataagaacg tttttcaagc ttatgatatg
     1981 cctttagata ttacattaga gaaaattgaa gcaaaattga ttcaattcct tggagattat
     2041 cgaacagatt caggcttgat tttattggta gatatgggtt cactaaacca actaggcggt
     2101 ttattagtga atcatctaaa tggaccactg ttaatcattg atcatatcaa tacaccgtta
     2161 ttattggaag tcggccaaca agtattaaac aataaaagta tcaccgaaat aggagcagaa
     2221 attgaaacaa gtcttacttt caaaaagcag ttactacttc ccaagaaaaa gaaaaagaaa
     2281 gccatcatta cttgttgtta tacagggatt ggtagtgcga cccagattca ggagatttta
     2341 acgaaatgct tgaaagatgc agttagagaa ttagtaatta ttccgtatga ttacaaaaag
     2401 ctgttagaaa acaagaattt tgagactcct tttcaattat acgatgtcat catgattgta
     2461 ggtacagaag atcccaaaat taatcagatt ccatatattg gattagatcg cctgattaat
     2521 ggggaagcaa ttggcgaatt tgttcattac ttggaaaaag agctgactat tgaagtgaac
     2581 gatttacaaa aagaattaat tttcaatttt tcaattagta aaattgtcga aaatttaacc
     2641 attttggatc cagataaggt gctatctttt gtacaaaaag caattaaaga attatcgaag
     2701 ttattaaatt ttgatttttc taataatcag ctgtttttgt tgtaccttca ctgtagttgt
     2761 atgattgaac gaattgtacg taaagaaagt gtggatgagc aagaggacat tgaagaatat
     2821 atgcaagcaa atggagaaat aatggataaa attcatagcg ctttttttga gattgaaagg
     2881 gaatacacaa ttgaaatacc agatttagag ttgcgattat tgagcgatat tgttcaagga
     2941 taggagtgaa ttcgaatgac aatgggagta atttttgata tggatggggt actcatagac
     3001 agcgagacat tttattttga gagaagaatg aacttctttc aagaactgga gatagatcca
     3061 ggatcaaacc agattgatga ttatgtgggg aaaacagaag ctgcaatatg ggaaacatta
     3121 gttcctgagg acaaatcatt aagagaggaa ctttatccga aatatgtaga ttatcgaaaa
     3181 acgcatccaa ttgatttcgc taaagattta cgaaaagaag tgaaaccgtt acttgacttc
     3241 ctcaagaagc gggatatacc attggcactg gcatcttctt ctccagttgt tgagatagag
     3301 agtatgctca ttcaatgtga acttactgaa tatttttcct ttgttataag tggtgagtca
     3361 ttaaaacaaa gcaaaccaca tcccgaaata tatttaaaag cgaaacagca attagactgt
     3421 gacttcttta ttgcagtaga ggattcaacg attggtatta aatcagcaaa ggcagcaaat
     3481 atctatacgg tggcactaaa acaaccaatg caaatcgatc agagtgaagc agacatacaa
     3541 attgaaagtc tacaagaact ggaacaaatt gttttagaaa aaggttagtg aattaatgga
     3601 aataaggcta tatatctgtg ctagctattt tgactaacca aaaaaacttg ctataattca
     3661 ggtgtagtaa aaggtgctgg taacaccttt tacgaaaatg cttcggcagt gataatggga
     3721 ttggcttttt aagtttttta ttttgttcgc aatccctaag gtcatgtgaa tgatcctagg
     3781 gattgctaga atattttgca acattctatc tatttcagaa cgtaaccttc cccagttcat
     3841 tgggattcat tagcatacaa ccaacatttc aaaaagaaat tgcactacac cattattagc
     3901 tattttgact aaccccaaaa aacttgctat aattcaggtg taggtaaaag gtgctggtat
     3961 caccttttac gaaactgctt cggcagtggt aatgagtgtg gcttaaagga ctagtccttt
     4021 aagcttttta ctttgttcgc aatctctaag atcaagttaa tgatcgataa gattgctaga
     4081 atattttgca acattctatt tcagaacgta acctttccca ttccactgtg attcattggc
     4141 aaccctcctc acaaccaacg tttcaaaaga aattgtaaag ttgttggggt accacgaccg
     4201 aacaatacta cacctgaatg atagtaagtt gtctcattaa gtatagcata tcctcttttt
     4261 gggtaaatag aaatcggtta cattttttat ccaagaccaa gttttttcat ttggtcttat
     4321 ttgctatacc caaacaattc cgcagtatag tcgacggtat tgattttatc aggtgagtaa
     4381 tagaaacttg ttttccttcc ccaaaacatt acctataaag gagaaaaaat ggtatcgtaa
     4441 ttatataggt ataggatgaa atttttttct aagaggaggg ttgttgatga aaaatttaca
     4501 gttaaaattt attgttgatc catcgattgt acgctggttt cggattatca atcaatttga
     4561 gcgcaatcaa cttgccacaa aaggagaatt agcaaagagt aatcatgtat ctgaacgaac
     4621 cattcaaaca gatgtcaata aaatgaagga ctacttttct gaaagtgttc aatttgtttc
     4681 aacgaaaagt gggtattctt ttcagaagga aagaccggtt ctttttctca agcagaagga
     4741 gcaactactg gagaacgaaa ttttatttga gttgttaggg aatgtctttt atggcgaatt
     4801 ggaagatatg acggagctaa ttgatcgttt tcatttatct gaagcgactt ttcgtcggta
     4861 tttgaagcag attcaaccag ttttggaaga atacggctta gaattgagtc tttatcctct
     4921 tgatttaaaa ggagaagagg caaatattcg caagtttttt aaagacttct attatgaagg
     4981 ggagatgacg ccccatactc ttgttccacc aagggatctt catgaacttg tgcaagctac
     5041 attctatgat aaatttgagt atttctcgat tggaacaggg acttctcctg ctgaatttta
     5101 ttatagtttg tatattgcga ttgagcgtgt gagacaagga aaaacgatag ccattcctca
     5161 aggtctgatt gagcgagtaa ttgctagtga gaattttcgc ttaatgtatt ccttgaaaga
     5221 agcgattcaa acaaattatc aagttgcttt atcagaagag gagttttgtt ggttgtat
//
LOCUS       DADQDV010000132         5207 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.136, whole genome shotgun sequence.
ACCESSION   DADQDV010000132 DADQDV010000000
VERSION     DADQDV010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5207
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.136"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            34..1368
                     /locus_tag="J8S10_002919"
     CDS             34..1368
                     /locus_tag="J8S10_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631451.1"
                     /translation="MDAAFLFSCLYTFATYRTVDIYYRSAIAEAIALTIIPAVLYYAY
                     GLIFNREKKVIALSVSISLLVYTHVLTTLLCSALIACMIIVRLFLSKQIKNDIKFVVV
                     NLVKAVFLTCALTSYFWYPMLQQMNYQEIHSPFKTDLQLEALSISDSIIQALNNDITT
                     YTMGLLGLVALIFPLFILKEMEKKEKIIYVGVVSTWVCVTNLFPWFLFQKTPISLLQF
                     PWRILGIQIFFSSMIITLVFMKKTMNKKYSWLIIGATVVFLLVTSIAAKENYAKVIQS
                     KHGHIVINEETLPRYTTSDMGGLYDYAPTEAIKERPHLEKHEVKVGESWEKGKYKAAD
                     NNITYTVASNKKQKVTVPVYAYLGTQVKVNGKVVNDSYKKHGLVNVDVNAGENKIEIT
                     TKYTPTALMALWISILTYCLVVYSSFKRFAPNKLKDSRYVTKKEINKKNENK"
     gene            1355..2989
                     /locus_tag="J8S10_002920"
     CDS             1355..2989
                     /locus_tag="J8S10_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631452.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIFIRLVSKGFKNADFI
                     AIFKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNN
                     DLTTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAK
                     LLQFPWRILSLQIIFSSLILTMIFFKNRRYNKTRELFYLFMTVLLLITLTVSSKKNFN
                     QKIISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIASLENKEHIIKHEAKIGSQWVNL
                     PYKTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEINHQPVKEQVNANGLVQISGVKGV
                     ADIKVSTSYTVTTIISYLVTLTAYLCLFFKIVFHKR"
     gene            3164..3997
                     /gene="msrA"
                     /locus_tag="J8S10_002921"
     CDS             3164..3997
                     /gene="msrA"
                     /locus_tag="J8S10_002921"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAZ9631453.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQGERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            4077..5066
                     /locus_tag="J8S10_002922"
     CDS             4077..5066
                     /locus_tag="J8S10_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-glyceraldehyde 3-phosphate reductase"
                     /protein_id="HAZ9631454.1"
                     /translation="MYIADSARYEKMEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQ
                     REILRGAFDMGITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMW
                     EGPYGEWGSRKSIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGK
                     ALYIGISNYNGEDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGA
                     ITFSPLAQGLLTNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQS
                     LAQMALAWNLRQKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
BASE COUNT         1825 a          806 c          951 g         1625 t
ORIGIN      
        1 agtttttatt atggagaaaa gttttttaaa aagatagatg ctgctttttt atttagttgt
       61 ttatatactt ttgcaactta tcgaacagtt gatatctatt atcgatccgc aattgcagaa
      121 gcaatcgctc ttacgattat cccagctgtt ttatattatg cttatggatt gatattcaat
      181 agagaaaaaa aagtcatcgc tttatctgtc agtataagtc tacttgtgta tactcatgtc
      241 ttaactacac tattgtgtag tgcattgatt gcttgtatga ttatagttcg tttgttttta
      301 agcaagcaaa taaaaaacga tataaaattt gtggtcgtga atttagtaaa ggctgttttt
      361 ttgacttgtg cattaactag ctatttttgg tatcctatgt tgcagcagat gaattatcaa
      421 gaaatacaca gtcccttcaa aacagatttg cagctagaag cactttctat ttcagatagt
      481 atcattcaag cgttaaataa cgatattaca acatacacta tggggttatt aggattggtt
      541 gcgttgattt ttcctttatt catactgaaa gaaatggaga aaaaagaaaa aatcatctat
      601 gttggcgtag tttctacatg ggtatgcgta actaatttat ttccatggtt tttgtttcaa
      661 aaaacaccga taagcttgct ccagtttcct tggcgtatct taggtatcca aatctttttt
      721 tcttcaatga tcataacgct tgtttttatg aaaaagacta tgaataaaaa atattcatgg
      781 ttaatcattg gcgctactgt ggtgtttcta ctcgtcacgt ctatagcagc aaaagaaaat
      841 tacgcaaaag ttatccaatc aaaacacggt catattgtta tcaatgaaga aacactccca
      901 cgttatacaa catcagatat gggaggatta tacgattacg ccccaacaga agcgataaaa
      961 gaaaggcctc acttagaaaa acatgaagta aaagtaggag aatcgtggga aaaagggaag
     1021 tataaagctg cagataataa cattacttac acagtggcaa gcaacaaaaa gcaaaaagtg
     1081 acagtaccag tatatgctta tttaggtaca caggtaaaag taaacggtaa agtcgtaaat
     1141 gactcttata aaaaacatgg cttagtgaat gtggatgtaa atgctggaga aaataagata
     1201 gaaattacaa caaaatatac tccaactgct ctcatggctt tatggatcag tattctgact
     1261 tattgtttag tggtgtattc aagttttaaa cgatttgcac ctaataagtt gaaagattct
     1321 cgatatgtga ctaaaaagga gataaacaag aagaatgaaa ataaataaaa aagtagtaat
     1381 attgagtgga ttaattatag ttagtagtat atattctttc atctttttca aaaatacaca
     1441 gagtatttat accactggag atctttcttt tcacttatct cgaatcaagg ggttatcgac
     1501 tatttttacc agtccgatta attatgagac attcaattat actggatatg gtgtaaatta
     1561 tttttatccc tttctgactt tttttccagc tgtaatgtta tattggatga caaaaaattt
     1621 gattgtaagc tatattattt acgtttggtt attgaacttg tgtacaacac tcgtagctta
     1681 tcattatggc gagcggtttt taaaacaaaa aaaagcggca tttttattta gttgtctcta
     1741 tattttctct gcttatcgga cagtagacat ctactatcgt tccgcaattg ccgaagctat
     1801 cgcaataaca cttgttatcc ctgtattatt ttatgcttat caaatcatct ctggaaaaga
     1861 agaaaagtat ccgtctgtaa agctagcatt gagtatgagt ttgctagtgt acagccatgt
     1921 actatcaaca ttaatgagta cagcattaat tatcattttt atttttattc gtttggtttc
     1981 taaaggtttc aagaatgcag attttattgc tatatttaaa aaattattta gtgcggcagg
     2041 aatgacattg gttctgacga gtgctttttg gtatccgatg tttgaacaaa tgctctacca
     2101 aaaaatcaac aaacctagcg tgacaaattt atatgctcat gcatctaatg tgttcgatag
     2161 tctgactgaa gctatgaaca acgacttaac tacttactca atgggactag ttggtctgtt
     2221 atctttatgt attcccctga ttttatttaa aaaattaaca aacatagaaa aaaagattta
     2281 ttatggtacg tgtttgactt ggctagctac aactagtttg gtgccatggt atcttctgca
     2341 aaatacgcca gccaaattgt tacaatttcc ttggcggatc ttaagcttgc aaataatatt
     2401 ctcttctctg atattaacga tgatattttt caaaaataga agatacaata agacaagaga
     2461 actattttat ttatttatga ctgttttgtt attaatcact ttaactgttt ctagtaaaaa
     2521 aaatttcaat caaaaaataa tttctcagcc gggacatatt gttgtaaaca aagaaacagt
     2581 agaggcgtat accactaaag gaatggatta ttttttatat gattattctc ctatcgcttc
     2641 attggagaat aaggagcata taataaaaca cgaagcaaag attggcagtc aatgggtaaa
     2701 ccttccttat aaaacaactg gtagttctat catatataga gtaactaatg agaagagcca
     2761 agtaatcaca cttcctgtat atgcttattt aggaacgaat gtagaaataa atcatcaacc
     2821 tgtaaaggag caggtgaatg ctaatggatt ggtacaaata agcggagtca aaggagttgc
     2881 tgatattaaa gtaagcacaa gttatacagt aacgactatt atttcttatc ttgttacatt
     2941 aactgcatat ttatgtttat tttttaaaat agttttccat aaaaggtaaa ttaacttttc
     3001 atttataaaa taaattgatt aaaaaggaga atctgtcgat aaggattctc tcttttttat
     3061 acgaaaaatc tgtaggggga tgaagtaatc gcttatttcc tcactttatg ataaattaca
     3121 gctaaagtca ctagcttgtc ttcttcggaa aggaggagaa tctatggatg aggaacaaat
     3181 attcattcaa acactttata atctgatttt gaatccgaat acacgagatt gggaacgaaa
     3241 agtattgatt cagacaaaga atgacataag agaaaatata tccgttaaag aacagttatc
     3301 aaaactagaa gcaacactac gtccattagc tatccgaatg aatctgacgc ctgatgtaat
     3361 ggacttttat ttattgatta cggaaggatt tgataaggag caaaaatatg acttttccaa
     3421 gcatgccatg caagatgctg actatcaaga acgtgcagta tttgcagggg gatgtttctg
     3481 gtgtatggtc gagccgtttg aatcgaaaaa agggatccta tctgttttgt caggatacac
     3541 gggcggacat gttgaaaaac caaattatga tcaagtaagt ggtggttaca caggtcatgt
     3601 ggaagctgtg gagatcattt atgacacaag agaaataagt tatagcgagt tgctgacaat
     3661 ctattggcaa attactgatc ccacagatac atttggacaa tttcaagata gagggaagca
     3721 atatcgtcca gtgatttttt atcaaggcga acgacaaaaa gaattagcgg aacaatcaaa
     3781 acagaaacta gacagttcag gaactttcca ccaaccaatc gtcacaaaaa tcgaaccagc
     3841 cggtacgttt tggccagcag aaaactatca tcagcaattt tacaaaaaac aaccgaaacg
     3901 ttataaaaaa atccagcaag cacgtaatca atttctgatc tatcaacgag taaaaaacaa
     3961 atggcaaaaa aatatacgaa aaaatcattt tgattaactc cttttcttta aaatgtagta
     4021 aactaaaaat agaaaaaaga aagcgtttta aaaagatttg atgaggagga gaaaaattgt
     4081 atattgcaga tagtgcacgt tatgaaaaaa tggaatatcg taaatccggt cattcaggtt
     4141 tgaaattacc gattttatct ctcggattat ggcaaaattt tggtgattat gatcctatcc
     4201 ataatcaaag agagatttta agaggcgcat tcgacatggg aattacccat ttcgaccttg
     4261 cgaataatta tggaggccct gctggagctg cagagaaaaa ctttgggcgt atttttagag
     4321 aagattttca agcctaccgt gatgaactga ttatttctag caaagcaggt tatcatatgt
     4381 gggaagggcc atatggggaa tggggctctc gtaaatccat catttcaagt tgtgaccaaa
     4441 gtctccaaag aatggggcta gattatgttg acatcttcta tcatcatcgc ccagaccctg
     4501 atacaccttt ggaagaaaca gcagaagctt tgatgcaact tgtaagacaa ggaaaagcat
     4561 tatatattgg tatatccaac tataatggag aagatacaaa aaaaatgact gaaattttaa
     4621 aaagaaagga agcaccgttc attattcatc agatgcgcta caatatgttt tctcgtgcac
     4681 tactagaaga cgatctatct ccagtattag aagaagaagg gctaggggca atcacgttca
     4741 gtccgcttgc tcaagggttg ctgacaaatc gttatctaca tggtattcct gaagattcta
     4801 gagcacatcg taaggaaata ccattccttt cagaagaaca agttggatca actctggaaa
     4861 aaatcaaagc actgcaaaca atcgccgtat cacgaggaca atcattagcg caaatggccc
     4921 ttgcatggaa tttgcgacaa aaatctgtta caagtgtact ggtcggagca agtcggttaa
     4981 gtcagttaca agaaagtgtt cgaatgatgg ataatttaga tttctcacca gaagaagaat
     5041 tgagaatcga ccaaattcta gaatagaaac gatgtaatca aactttttat ccatatatta
     5101 aaaaaaacaa aagatgacat caagaatcga atgaagatcg tctgttattg aacatcatat
     5161 tttttgtcgt tcaaaataaa aatgatcgaa ggctaggagt gaatttt
//
LOCUS       DADQDV010000133         5024 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.137, whole genome shotgun sequence.
ACCESSION   DADQDV010000133 DADQDV010000000
VERSION     DADQDV010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5024)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5024)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5024
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.137"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            283..522
                     /locus_tag="J8S10_002923"
     CDS             283..522
                     /locus_tag="J8S10_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631455.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            complement(884..1144)
                     /locus_tag="J8S10_002924"
     CDS             complement(884..1144)
                     /locus_tag="J8S10_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631456.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVVGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(1329..1826)
                     /locus_tag="J8S10_002925"
     CDS             complement(1329..1826)
                     /locus_tag="J8S10_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HAZ9631457.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
     gene            complement(1956..2666)
                     /gene="budA"
                     /locus_tag="J8S10_002926"
     CDS             complement(1956..2666)
                     /gene="budA"
                     /locus_tag="J8S10_002926"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HAZ9631458.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            complement(2679..4343)
                     /gene="alsS"
                     /locus_tag="J8S10_002927"
     CDS             complement(2679..4343)
                     /gene="alsS"
                     /locus_tag="J8S10_002927"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HAZ9631459.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            complement(4548..>5024)
                     /locus_tag="J8S10_002928"
     CDS             complement(4548..>5024)
                     /locus_tag="J8S10_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAZ9631460.1"
                     /translation="CIVMIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLFAWIV
                     SVIMIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVLRIAF
                     YYTLKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTMDL"
BASE COUNT         1528 a         1043 c          771 g         1682 t
ORIGIN      
        1 ctatcctcct agcaactatt taaataccca aaaaaattac ctctagataa tatcatacct
       61 acgttttcac ttataaattt tttcataaaa aaagcgttta gaggcataat cgttaataca
      121 gatggtaacc aatgtatctg gtttgaactg ggatatcacc ctctccatat atgtattact
      181 aagactaata gatactataa aagacttgat agttttgcat tgattttgcc taatactgag
      241 cataggtgta tgctaaacga tactataagg agtgtgtaca taatgaaaag aattctgttt
      301 atcagtttat caaatttatt gttacttact gcttgtggga cttctgcatc aaagaacata
      361 ccttcagata cgcaaatttc gaatagtatc gattcaacaa tttctacaaa tgagaaaaat
      421 tctccggtag aaacttccga tataaaagtt tctacctctg caaaaaacag ggtaaagaaa
      481 ctgtcagcac gtctccttta tttcaaacaa actctgaatt agcttcttca tcttcttcag
      541 caaataatga tgatagtttc gcgtttactc ctaactaaat gcaaccttta caaatgcttt
      601 acgataacaa gcctgagcta aatgatcctg atatcagttt tgcatttttt gaaatgattg
      661 gatcggatga tctttttaaa actactagtt tgtctatccg aaaataggac agttctggca
      721 gtataggttt ttatcgagtt tctccaccag gcctcgttac agagacagat tctctaggcg
      781 aaccttttga ataaatcaaa aatcatgaac aatcactgcc aactaaataa agtgccttca
      841 aaagcttggt cttctcgctt ttgaaggcac tttatttaaa tctttatgaa actaaagtat
      901 gttcatattt gttgctatag ttatatagat attctgttgt ttccaactca taaacgtgag
      961 tatattttgc cactactttt ccgcattttt ctaatatttc attgcgatcg acgtcatgat
     1021 attcgtctac gcagatcaca acacaatttt ctaatttact gattacttct ccaaccactt
     1081 tttgtttcaa gccaataggt tggcaaatat atttttttcc taaaatgata gtttcgttat
     1141 tcatatttca tccatcctta atgtttttcc attatttaaa atgataatac cattaaaata
     1201 tgattatgaa aatcaataac acttgtgatt ttataaaaaa ataaaaaaac cgaaaaacag
     1261 aaatgcccac tgtctttccg gctcttttta ttcttgattt ctcttctttt ttgtttcaat
     1321 agacgatttt agttattaat aaatgaaaaa gcatttatat taaaatttgc taataaaaga
     1381 tctacatatt tttctagaaa tgcttgatcg atttcatcat accctttcgt tactccgcaa
     1441 tcgatatcta aaacaccgat taaattacct tcttttacca ttggcactac gatttctgat
     1501 tgtgcggctg aatcgcagga aatgtaattt gcatgggttt tgacatcatc aacgatcaat
     1561 gtttcttgtt tttcagctga ttctccacaa actccttttc ccatcttgat acgtgtgcaa
     1621 gaaactcgcc cttggaacgg tcctaaaatc aattcattac catcgaataa ataatatcct
     1681 gcaaagacag tctcaggcaa agtctcattc aacaatgcag atgaatttgc taaatttgct
     1741 aaccagttat cttctgcttc taataatcct tgttgctgta ataataaaat ttcgtatgca
     1801 tcttttttct gtttttctgt ccacatgata aaaaccgctc ctttttgatc tatggagaag
     1861 attatagctc agtttttttg taaacgctag gtttcctcct caaaaaaacg agatacgtca
     1921 ggttaatcac cttgaacgca tctcgctgtc tttttctatt ctgcttgttg gatttctgct
     1981 gctaaatcag cataatcaat cgtttcgtga acaaaagtcg gatcatcaac tggaaaatgc
     2041 tgtacaaggg acgagatgcg gctaatctca acttttcctt cagccacttc aaaatccatt
     2101 acatgtccgc caaatgtatg tgtatcatcg ataaaatgca agtgaaatcc cgctgcagca
     2161 actccttgga ataattcagg cgtaaagaac ccgactaatg ttccttggac attgctttgt
     2221 tggaattctg gttgagactc tgaaattttt gctagtcttc tgtaaggttt ttcttgcttc
     2281 ggcatgatac ggatgtgcat atttttgaat aatccagtta tcttcactgc caaaaatagg
     2341 ttttccccgg cttctcttac taatatgtct tttttcaatt gttctccatc tgcagttttt
     2401 gagacagaaa aactagtatc tggcgtaaaa tctgtaattg ctgcataggg ggtaagttca
     2461 cttccatcta attgggcaac tgagccatct gatcttcctt gataagctac gccatctaaa
     2521 aagatgactt caccatcaag cccatgcaat gttcccaatc ccagagttcc tttttctaat
     2581 atatgagcaa tcgtttctgt tccatccatc aagccagcca tcaaagctcc taatgtcccg
     2641 tgctggtata agattttttc agtcatgtcg acacttcctt aatagaattg atctggtaag
     2701 attgtttctc ccaatttctc attatcacgg taatcaatcg gaatatcaat aattacgggt
     2761 ccttctgtcg caaatccttc ttctaaagct ttttctaatt cctctacact tgtagctcgg
     2821 attcctttag cgccaaaagc ttctgcatat ttcacaaaat caactggacc aaagtctaca
     2881 cctgacgccc gctgatattt cattttttct tggaactcta ccatattgta gtgtccatca
     2941 ttccaaatca aatgaacgat attcaatttt ttacgtaccg ccgtttctaa atcctgggca
     3001 gagaataaaa atcccccatc gccggaaact gatacgattt gtgtatttgg acgcaccaat
     3061 gcagcagaaa tcgcccatgg caatgcaaca ccaagcgttt gcataccatt actgaataac
     3121 aaatgacgag gttcataact tctaaagtgg cgtgccatcc aaatataatg actacctaca
     3181 tctacggtaa cagtcatatc atctgttact tttgactgaa gcgtgttaat aacttctaaa
     3241 ggatgcaaga tacctgcttc tccttttgat tgaacaatgt cccgctccgt taattctgct
     3301 tgaagagatg ctaaatattc ttttgcatct tctgacactt gttgaggctc taatgaacct
     3361 gtcaataaat caagagtggc tgagatatca ccgatcaatt ctctttcagg ctgcataaaa
     3421 ggatcgattt cagctggcgc ttcatcgatc acaatgatcc gcgcatcttt ttccgcattc
     3481 cagtttcttg cttcatattc gattggatca tagccaatag caataactag atcacttcgt
     3541 ttcaaaagca tatctcctgg ttggtttcta aataaaccca cacgaccaaa gaaatgcgct
     3601 tctaattcac gtgagatcac tccagctgct tggaatgtct ctacaacagg caatgctgtc
     3661 tttccaacta attgcctgat ggctaacgtt tctttttcac ttgatcctcg catacctact
     3721 aatagtaccg gtagttttgc ttctctaatg cgttcagcta ggtaacggat atcatctgca
     3781 gaagcagaac ctaatttagg atcgctcaat ggcttgatga cattcccttg gacaggtgca
     3841 tccactacat cttgcgggat actgataaag ctcgcgcctt tttttgaact cttagccata
     3901 cgataagcat tggcaatcac ttctgaaatt gtttctggat cttggatttc tgcactgtat
     3961 tttgtgattg gctggaacag tgctgcatta tccatgcttt gatgggtcaa cttcaataga
     4021 tcgcttcgtt ttacttgtcc ggcaattgct aaaactgggt caccttctgc tgtcgctgtt
     4081 accaaacctg tagctaagtt actagcacca ggaccacttg ttgcgataac tactcctggc
     4141 tctcctgtaa tacgtccgat tgcttgtgcc ataaatgcag cattttgttc gtgacgagtc
     4201 acgattaatt caggaccttg atcctctaat tcattaaata caccatcgat ttttgcacct
     4261 ggtataccga atacataatc aacatgatga ttaatcaaac tttctactac agatttcgaa
     4321 ccttgtttca ttttttcgtc cattgaacat cgtccttttt atgctttatt tttaattatt
     4381 agttagaaat aatcacaaat aattgataca gtttctaaac ctgtttcatt caaaagtata
     4441 gcacgtttta tttcatttgt ttagccatat gtttcaaaaa atgaaaaaga atgacagttt
     4501 ttacataaaa actgtcattc ttaattgaaa gtttcaattt ataaagtcta cagatccata
     4561 gttctcatca atttacgatt gttgaagtaa atcaaaccaa atacgataga aggacctagt
     4621 agaatacacc attggggctt tacgaaaaag aagagaaaca aacttgtcaa tagtaaaaaa
     4681 tctagtaaac tcacatacca ttttttcaac gtatagtaga acgctatccg tagaacttga
     4741 tttggtttcg acgctggatt tctcacctga aaataccagt agttgatgct aaaggaaact
     4801 gataaacaag caagtaaaac aaacaacgga atcaaccatt ttccataaga aaaacgtata
     4861 aaaaagaaac aatcaaaaat cattatcaca ctaactatcc aagcaaatag ccaataaaaa
     4921 aatcccttta gccaaaattg gcgaaacgtc tttatgaaca aacgtactgg tgaaaaactt
     4981 ttttcttttg ctaattcttc tgtcatacct atcatcacga tgca
//
LOCUS       DADQDV010000134         4949 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.138, whole genome shotgun sequence.
ACCESSION   DADQDV010000134 DADQDV010000000
VERSION     DADQDV010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4949)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4949)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4949
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.138"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            128..1771
                     /locus_tag="J8S10_002929"
     CDS             128..1771
                     /locus_tag="J8S10_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HAZ9631461.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKLALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(1844..2389)
                     /locus_tag="J8S10_002930"
     CDS             complement(1844..2389)
                     /locus_tag="J8S10_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HAZ9631462.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(2412..2897)
                     /locus_tag="J8S10_002931"
     CDS             complement(2412..2897)
                     /locus_tag="J8S10_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAZ9631463.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(2887..3699)
                     /locus_tag="J8S10_002932"
     CDS             complement(2887..3699)
                     /locus_tag="J8S10_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HAZ9631464.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(3838..>4949)
                     /locus_tag="J8S10_002933"
     CDS             complement(3838..>4949)
                     /locus_tag="J8S10_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HAZ9631465.1"
                     /translation="PILYLMEQPALSVSQSFLDKNEISYMTHTSGTTGIPKLICHSAH
                     SMGWRTKWQKTVFTKISEKKLIAFHISPVHSRFNIGISSLMSMGFPMMPLANAQSSKV
                     VHMLEAHRPIALETHPNNFVQWRFTAKEHPEAFSGIRYYHSTFDAINNQTMKTFLRTS
                     MAQDAVFLQVYGQSECGPMILKAHTLESLKTSDARDMGVGLEDMTSARITDSVGNVLP
                     ENTDGHIQLLSKGRALTYYKEDARFQENVYGDWWDSGDYGFMDKHGHLFLKDRQVDLI
                     ETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSPQPIIALAPDKEMDWNRWWEQVHELP
                     RLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQKS"
BASE COUNT         1595 a          977 c          946 g         1431 t
ORIGIN      
        1 aaaataaagc tcaacgaacg cacttagcag attcgttgag cttttcgttt ctagttaccg
       61 gtaacaagga tacttctaaa atagaatcgg ttataatcaa gagggaccgt taaaggagtg
      121 aaacgatatg atacaagaac aaaaatggtg gaaagaagca gtaggctatc aaatctatcc
      181 tgctagtttc aaagatagca atggcgatgg tcaaggagac atcaatggga tccgtgaaaa
      241 acttaattat ttgaaagatc ttggtatcgg ctttatctgg atcaatccga tctatcaatc
      301 tccatttgtc gataatggtt atgacgtaag tgactatcaa gatatagaag agagattcgg
      361 aacgatggaa gattttgatt tattgctaaa agaagcacat gaattaggga tcaaagtgat
      421 tatggatctt gtcatcaacc atagttcgga tcagcatcaa tggtttgaag aatcgaaaaa
      481 atctaaagaa agcccgtatc gcgattatta catttgggtc gacggggtag atggcaaaga
      541 accgaataat tggacatcga ttttcggcgg ttctgcttgg gagtattctc atgaaactgg
      601 acagtattat ctgcatgttt ttgcaaaaga acaaccagac ttaaattggg aaagcgagaa
      661 attgaaagaa gaactattca atatgatccg atggtggttg gataaaggga tagatggatt
      721 tcgtttagat gcgatttctc atgtaaaaaa agatgaatat tcagtaaaag ccacagagaa
      781 ccctttctca ccctttcaaa atgtctcagg aatcgaagaa catttgaccg atttgaaaca
      841 tgtttttgaa gagtacgata tcatgactgt cggagaagca agtggtgtca ctgcagaaga
      901 aggaccacaa tgggtaggga aagacggtta tttcgatatg atattcgaat ttgatcatat
      961 ccatatctgg cagcaagaaa aagaagggca attagatgtc cttaaattga aacttgcatt
     1021 aagcgcttgg caaacttcat tggatggtat cggatggaac gctttatata tggaaaacca
     1081 tgatgttcct cgtgccgttt cagtgtttgg agatactcgt cccgattttt gggctatgtc
     1141 tgcaaaagca atcgctatga tgtatttctt tttgcaaggt acgccattta tttatcaagg
     1201 acaggaaatc ggaatgacga atatgccctt tgaatcgatc gatcaagttg atgcagtaga
     1261 ttcgaaaaga ctttataaaa ggctgcttgc ggaaggtaag acaagagaag aagcattgga
     1321 tatcattcgt gaaacaacga gagacaacag caggacaccc atgcaatgga cttcggaaca
     1381 atatgctggt ttttctacac atgaaccttg gctgatcact aatccaaata ccaaaacgat
     1441 caatgtagaa caacaagaat atgaaccaga gtcggtcctg caattctata agaacatgat
     1501 ccgcattaga caaaccaata aaggtctgat atacggttct tataaagaat atcttcatga
     1561 acatccacaa ctttatgtct atgaaagata tttagaagat gaacaatatc ttattatggt
     1621 aaacttaaca gaatcacttg ctgactatga acttccaaaa gaagcagatc agtcctggac
     1681 attactcttg tcaaattcct ctagcggaga atttgaagct aaaggcatac tagcacctta
     1741 tgaagctcgg ttatataaaa caaacaagta aaacttcctc gttaaagttc attagttgga
     1801 ctttgcgagg aagtttttca gattgctctg tcaattactc atttcaataa ttcgctctag
     1861 gaccaccgat atatttagga cgagagcgaa gggctgtcac gtgagcttgt ccaagggttt
     1921 tcaaacgagg tctgacaggt acttggacat gtttgatatg cataccgatt gatgtgtcac
     1981 cgatatcgat accggcttgt ccaactacgt gttccacttc gacaggatca ttgaactggt
     2041 caaaagcagc aacagaacaa gcacctccag catgtagtgc aggaacaaca gagacaattt
     2101 cgaaattttt tgcttctgcc actgttcgtt ctactactaa tgctcggttc aaatgttcac
     2161 aaccttggac agctagcgca atttctttag gatccaacaa ctcttttaac gtacggatga
     2221 tccattgacc aacttccgca ctggaatttt ttccaatatg tcctccaacg acttcgcttg
     2281 tgctgcatcc taaaacaaaa agatcacctt ttttcaagtg tgcctcagcc aatatgtcat
     2341 taactatttc agtcaattgg tcttttaatt ctttttctga caacttcatt ttctaaaacc
     2401 ttctttttca attaatattg cttccgtgct tgaatacgtt gaagacttgc agttatagga
     2461 aaggcaagtc ccattccaat cagattttgg aagatgtttc ctggtataga agccactcca
     2521 gccggccaat catataaaat ccaaccggcg ataccatagc cgatgatcat aactaagctt
     2581 cctaataaaa gccctaatcc ccacatacga gtagaagatt tgctgaaaga accagcaaca
     2641 tatccttgta acccgtggat cactaatgaa aaaactgccc actgcggata tcctgaaatc
     2701 aaatcgatca atagaccact ggaagcacca acaactaatc cacccgttgg accataaaga
     2761 aaagcagcgg tatagatccc ggcctcgcat aatgtcacaa atccattcgt agccggtaca
     2821 gggatcaaaa ttgttaatga aagggcaact gtcaacgcaa tcagcatagc atagatcgtt
     2881 aattgcttag ttttcatttc tcattcctcc tttttgaata ccgccagacc agacacttcc
     2941 ggtatgatcg ttcatcagca cgccattaga aatacaatgg gcaacaaatt ttttactttc
     3001 tgctactgct ttggtaaaat ctgcccctaa cacaagattc gctgttattg cagaagaaaa
     3061 ggcacaaccg gccccgttta ctgttgtagt gtcgattttt ttatgagaaa atacctcata
     3121 atgatcaatt gaatagagaa gatccacagc ttcatctcca gccatccttg tgccgccttt
     3181 gatcacaatg ttttttgttc ctgaagcagt gagttcttta gcgagatgga tcatttctgt
     3241 taacgaagag ggaagagctt gaccagaaag taaagcagct tctgccaaat taggcgtaat
     3301 catcgtaaca agtggaaaaa gttcttcgat gagctgcgaa atatacaatt gattgatcac
     3361 agcttcagtt tctttgaatg ccaaaacagg gtctaaaatg attgggatat tttgttttgt
     3421 ttttatgaag tctcgaacaa ccatgattgc ttcacttgaa ttcaataacc caattttgat
     3481 accatctaat gaagtcattt tatcaatcga aactaactgt cgtttaagca attccaaaga
     3541 tatagattcc agcataaatc gctcattaat atctagtgcc cctatagaag tcaaggcgct
     3601 tagtccgaat agaccaaaat tctcaaaagt ttttaaatct gtttggattc ctccaccagc
     3661 aaatggatca gaaccgccaa ttgtcaagat tcttttcata acattttcct ccatgaataa
     3721 gagtataacg aaattttcaa aaaagaaaaa cagccaattg gcatattttt atctcatcca
     3781 atttaaaaaa acaaaaagaa aagaaagacc aaaatggatc tttctttcct taaatagtta
     3841 ggacttttgt gattttaatt ctttctcgat ttgaagccgt tgcactttca ttgtagctgt
     3901 tcgcgggatt gcatcaaaat cacggatgat agggacgttc aagcgaggaa gttcatggac
     3961 ttgctcccac catcgattcc aatccatttc tttatcagga gctaaagcaa taatcggttg
     4021 tggagaatga tttttatccc ttacaatcac tacttctgcc aaaaaatcta acgaatctaa
     4081 taaaaagtct tcaatagcta atgtactatt gatcgtttcg atcaaatcca cttgccgatc
     4141 tttcaaaaat aggtggccat gcttatccat aaaaccgtaa tctccgctat cccaccaatc
     4201 gccataaaca ttttcctgga accgtgcatc ttccttgtaa taagtcaaag cccgtccttt
     4261 agacagtaat tgtatatgac catctgtgtt ttcaggtagg acattcccaa ctgaatctgt
     4321 aatccgagcg cttgtcatgt cttccagtcc aacgcccata tctcttgcat cacttgtttt
     4381 caaactctct agtgtatgag ccttaagaat cattggtccg cattcacttt ggccatatac
     4441 ttgaagaaat accgcatcct gtgccatcga cgttcgcaaa aatgtcttca ttgtctggtt
     4501 gtttatagca tcaaaagtgg agtgatagta tcggataccc gaaaaagctt ctggatgctc
     4561 cttagcagta aaacgccact gaacaaagtt attcggatgg gtctctagtg caattggccg
     4621 gtgagcttcc aacatatgaa caacttttga actttgtgcg tttgctaaag gcatcatagg
     4681 aaatcccatg gacatcaaag aagagatacc aatattgaat ctggaatgca ctggagagat
     4741 gtgaaaagcg attaatttct tttccgaaat ttttgtgaaa actgtttttt gccatttcgt
     4801 ccgccatccc atagaatgag cagaatgaca aataagttta gggataccag ttgtaccaga
     4861 agtatgggtc atataagaaa tttcattttt gtctaaaaat gattgagaaa cagacaaagc
     4921 aggttgttcc attaaataaa gaataggaa
//
LOCUS       DADQDV010000135         4924 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.139, whole genome shotgun sequence.
ACCESSION   DADQDV010000135 DADQDV010000000
VERSION     DADQDV010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4924)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4924)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4924
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.139"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            83..970
                     /locus_tag="J8S10_002934"
     CDS             83..970
                     /locus_tag="J8S10_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAZ9631466.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1110..2036
                     /gene="cysK"
                     /locus_tag="J8S10_002935"
     CDS             1110..2036
                     /gene="cysK"
                     /locus_tag="J8S10_002935"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HAZ9631467.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2272..2718
                     /locus_tag="J8S10_002936"
     CDS             2272..2718
                     /locus_tag="J8S10_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAZ9631468.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2991..4343
                     /locus_tag="J8S10_002937"
     CDS             2991..4343
                     /locus_tag="J8S10_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH dehydrogenase"
                     /protein_id="HAZ9631469.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            4514..4801
                     /locus_tag="J8S10_002938"
     CDS             4514..4801
                     /locus_tag="J8S10_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631470.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
BASE COUNT         1693 a          813 c         1030 g         1388 t
ORIGIN      
        1 ttaaaagtat aatttaatta attaagtttg ttttaagaag agaacttttt attaagtttt
       61 tttattttga ggaggaattt gaatgcaaga gctgaagacc cgcagtgccc ggcaccatag
      121 acctaaaaga aaaatggtga tcaataaaaa agcgattgct cctttaattg gaacgagtct
      181 tttagttggg ccgatgatgg ttacagcggt accgcaacat gttcatgcag atgaacaagg
      241 atctcaaaca gtcgctgatc ctcaagcgtt tatcgatcaa atcggctggt ctgcgtcaga
      301 agttgctgca agtaatgact tgtatgcttc agtcatgatc gctcaagcgt tgttggaaag
      361 tgcatatggc acttccggat tagctagtgc gccaaattat aatctattcg gtgtgaaagg
      421 aagctataac ggacaggtcg tttatatggc aaccaaagaa tatgtaaacg gacaatgggt
      481 aacgatgaat gagccattcc gaaaatattc ttcttattgg gaatccttcc aagaccatgc
      541 gaatgttctt cgttcaacca gtttttccac gggcgattat cattatgctg gcgtgtggaa
      601 aagcaataca acaagttttt atgatgcaac agcgtacttg acaggtcgtt atgctaccga
      661 tccaaattat ggggccaaat tgaactcatt gattaatact tataatttaa cccgttttga
      721 tacgccatca acaggttcgg ctacaacaac cacaagtaca acaacaacga ctactacgac
      781 gacttcaacg tcatcatctt caacaacaga tgtaaataca aataatggtc agacatatac
      841 agtcgtgtca ggtgatacgc tatgggatat tgcacaaaaa tttggcatgt ctgttgatga
      901 tctaatggcg aaaaatggca tgtctatgtc cagttattct ttattagttg gtcaagaact
      961 aaacgtttga tttagataaa aaggcaaaga aattaccata tatggtatat ctttgtcttt
     1021 tttttgctag tcaaagacga atcactcgcc ataaatgaac agattgtatt atgataagta
     1081 agaagagcaa agacaaggag gaattgaaga tgacagctat ctataactca gtcaccgaat
     1141 tgattggcaa aacgccaatc gtcaaattaa ataaaatcgt accagaagat tcagcagatg
     1201 tttttgtaaa gcttgagttt tttaatccag gaggaagtgt aaaagatcgt attgctttaa
     1261 gtatgataga aaaagcagaa cacgatggtc tactgaaacc aggtgatact atcattgaac
     1321 ctacttctgg aaatacagga atcggattgt cgatggtagg agttgcaaaa ggatataaag
     1381 taatcatcgt gatgcctgag acgatgagta tcgaaagacg tttattgatg aaagggtacg
     1441 gcgcagagtt gattttgact cctggtgcgg atggtatttc tggatcaatc agagaagcag
     1501 aacgtttggc aaaagaaaac ggctactttt taccattaca atttgaaaat gaagcaaatc
     1561 ctcttgtgca tgagaagacg actggtcctg agatacatca agcatttgga gtaaatggct
     1621 tggacgcgtt tgttgcaggt atcggtacag gaggaacgat cactggcgct ggccgagaat
     1681 taaaacgtgt gtatccgaaa atcgaattaa tcggggtaga accagcagaa tctgctattt
     1741 tagaagggaa agaagcggga cctcacaaaa tccaaggaat cggtacaggt tttgttccta
     1801 aaacactgga tacttctgtg tatgataaag tcctttctat tagtggagac gaagcgatgg
     1861 aaacagctag agaagttggg cgaaaagaag ggattttagt aggcatctca tctggcgctg
     1921 caattgctgc cgcgctaaaa gtcgcaaaag aattaggaaa aggcaagaag gtattagctg
     1981 tggttcccga caatggtgaa cgttatttat ctacagccct ttaccaagag atataaggca
     2041 cttggttttt ctccagatag gtttatgtaa aaaactttta aagatgaaaa gaacacacaa
     2101 aaatttatga tgagaaaaat tatttgaata gagacgtaga atagtgaacg cgactgtttt
     2161 acgtcttttt tcattaaaat acaataaaat tgaattttct tttcatgtta agtggatttt
     2221 aaaatgtaaa aatagtatga taagacgaga ataacaacgt ggggtgttta catggaaaat
     2281 aagttagtcg aagaggttat cgaaaagtta aaaaaagaga acattcgaat cacacctcaa
     2341 cggtacgcgg ttttagaata tttgattgaa catcattccc atccaacggc tgatgagatt
     2401 tataaagcac ttgaacatcg gtttccaaat atgagtgttg cgactgttta caataacctt
     2461 cgcttattta cttcgattgg atttgttcaa gaaatgaagt acggcgatgc ttctagccga
     2521 tttgatttca gttcaaagcg tcattatcat gtaatttgtg aaaactgcgg taagattgtt
     2581 gattttcatt acccagggct tgaagatata gaaatggctg caagcagact gactgatttt
     2641 gagattaatg aacatcggtt ggaattgtat ggactctgtc cggattgtaa agagtcagca
     2701 aaaaaggcgc aaatgtaaaa acagtttcta caagtgttat acctaaaaaa agctagctgt
     2761 gtaaaaaaaa cgctagcttt tttatttttt tgtcttttat tcacaatctt agatataaaa
     2821 gtgaatatta ttaaaataag aatcttgtag atattgggtt cttatgcttg aaaaggaatg
     2881 aaactacaaa caaacctttg tgaattcaca agcattaaac tgttgtatcc gttttatttc
     2941 tgttatagta gttttgtcga aggacaaaat gttaatcgga gggaccataa atgaaagtag
     3001 tagtaattgg ctgtactcat gcaggtactg cagctgtaaa aagtatttta aaaaatcatc
     3061 cagaagcaga agtgacagta tatgaaagaa atgacaatat ttctttctta tcttgcggta
     3121 tcgcacttta tgtcggcgga gtagtaaagg acccagcagg cttgttctac tcaaatcctg
     3181 aagaattatc ttcattagga gcaacagtta aaatggaaca cgatgtaaca gacgtcgata
     3241 cagaaaataa aacagtaacg gcaaaagatc tgaaaacagg agaaacagaa acggtttctt
     3301 atgataaatt agtgatgaca actggttcat ggcctattat cccaccgatt agtggaatcg
     3361 atgcgaaaaa tgtactccta tgcaaaaact acaatcaagc aaatgaaatt attgcacaag
     3421 cgaaagaagc aaaacgtgta gtaattgttg gtggtggata tatcggtatt gaattagtag
     3481 aagcttttgt cgaatctgga aaacaagtga cattgattga tggattagat cgcatcttga
     3541 ataaatatct agataaacca ttcacagata tcttagaaaa agaattgaca gaccgcggtg
     3601 ttactcttgc gctaggcgaa aatgttactg aatttatcac agatgaagaa ggaaaagtga
     3661 aacaagtagc tacaccaaca gatacatttg atacagatat ggtcatttta tgtgtgggct
     3721 tccgtccaaa tacaaaactg atcgaaggaa aagtagatac actgccaaac ggggcaatca
     3781 aagtgaatga atacatgcag acaagtaatc cagacatttt tgcagctgga gactctgcag
     3841 tagtcaacta caatccaagt ggcacgcaaa actatattcc tttggcaaca aatgccgttc
     3901 gtcaaggttt gcttgtggga aataacttga cagatcataa aatggcgtat cgtggtactc
     3961 aaggaacttc aggactttac ctatttggct ggacgatcgg ttcgacaggt gtgaccaaag
     4021 aaagcgcaac tttgaacgat ctagaagtcc aagcgactgt atttgaagat aattatcgtc
     4081 cagagttcat gccaactact gaaaaagtaa tgatggagct agtctatgaa aaaggaacga
     4141 atcgtatcgt aggtgctcag ttcatgtcca aatacgacat tacacaatca gcaaatacca
     4201 tgtctttagc tgttcaaaat aaaatgactg tagaagatct cgcactttca gatttcttct
     4261 tccaaccaca ttttgaccgc ccatggaatt acttgaacct acttgcacaa gcagcgctag
     4321 gcgaaatcga aactgcacaa taaagaaaaa gggttgtgac acaattttgt cacgaccctc
     4381 tgtctttttt tgtgaaaagt acaattagtt gtctttcttc gaattttttg tcacaataag
     4441 cagcaaagat aaagctgtta cataaaagaa caagcagctt tatttgattt tgaaaagaaa
     4501 ggtgagaaag aagatgaata aagaatattt tgtccaacaa gatgcatttt tagaagatta
     4561 taaaagtgct tcgaagaaat taacgatcaa tattgatgag ttggcagatc aagtactctc
     4621 tcagttgaat gaaacgcaag aggaatatta cacgatgcca gcaaatgacg ccaaagataa
     4681 tgtttctcat cgttttcctt tcagtagacg catctactca gatgaaaatg acggcacatt
     4741 gaatacagag tacacatatg aaggtcagcc atatgtgcta gaaactgatg atgatcttta
     4801 aagacagttt ttgaaaaggc cgctcatcct taagtgatga caaaaaatca tcacaattac
     4861 cgatgactgt ctctttacta tcttttaatc agaaaaaggg gttatgacaa gctttgtcaa
     4921 cccc
//
LOCUS       DADQDV010000136         4738 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.140, whole genome shotgun sequence.
ACCESSION   DADQDV010000136 DADQDV010000000
VERSION     DADQDV010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4738
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.140"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(25..1023)
                     /locus_tag="J8S10_002939"
     CDS             complement(25..1023)
                     /locus_tag="J8S10_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HAZ9631471.1"
                     /translation="MKKWLLLLIGMGILFTGCTSENTRTKATIETDTTIETKKSKTQS
                     TEQTTTEMKQSVETSASSITESSSEEVKNTLWDTNKASKLETFVTQWGKTLGQEYKSY
                     NLQNNVSLYGTPLPQAVINGDWKMAINEAPVTVQWSEDGTGHADFNLVAVYSDVETGE
                     YLGQHVYFFGFQNGQPKVYLTQQNQGNENNYLYFNETQNQQLKQGFSDIVNGQTPQTP
                     VVEESTQQATTTTTQSTSSSGISSWEAAKESVLNNKALWLYDSPDKNVSNTNLISTNE
                     YMKDLMQDENGSYYSINIVTDDDGNTTMAGGKQFRVYTDGRISQRIGMTNNFQMIK"
     gene            complement(1098..1394)
                     /locus_tag="J8S10_002940"
     CDS             complement(1098..1394)
                     /locus_tag="J8S10_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631472.1"
                     /translation="MAKLIVLGGLIYGGYWLYQYMLAHPNIDKGKVIKTVGVIIVGLI
                     ALTKKNNTNSPKIMRTYRCRGCGREISTSFNPSESPQGRDRCHTGYRHYWERID"
     gene            complement(1387..1680)
                     /locus_tag="J8S10_002941"
     CDS             complement(1387..1680)
                     /locus_tag="J8S10_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631473.1"
                     /translation="MEIDETCLSNSYKSMNDFFEEMELDSELLYQFYLAFRGQQISFP
                     MKMYDRELVRKRIENMIEQEKTVDIRQLTEVYGFSARWIQKVIKQKERRRVHG"
     gene            complement(1826..2377)
                     /locus_tag="J8S10_002942"
     CDS             complement(1826..2377)
                     /locus_tag="J8S10_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1643 domain-containing protein"
                     /protein_id="HAZ9631474.1"
                     /translation="MIEKELVTTQTEVWRDPHHTHRYVFKRQWAIKGKEAEDKLAVVI
                     TIRPTDTEPFTNDLSMLLIEKNIRQLGFTGFIAVNLFSYTKAKSPRVFLRGNDEQSLE
                     ILTTVFTEKKINTIIFACGSITATSQVAYEQAKTIYDQLSAKQKKMTKVLINAEGKLS
                     HPLSIHVRNEWQLADSQLLFQEK"
     gene            complement(2551..2850)
                     /locus_tag="J8S10_002943"
     CDS             complement(2551..2850)
                     /locus_tag="J8S10_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="HAZ9631475.1"
                     /translation="MLETAIEVLEKCAQLVTASEEWGYESVTMEKEEIEMGMLPEDVH
                     LPRLVMTHLYIYCAPEDGKDYVVYFITDITSQREFVRGLLVEGRLVWSQIGGTDE"
     gene            complement(2877..3143)
                     /locus_tag="J8S10_002944"
     CDS             complement(2877..3143)
                     /locus_tag="J8S10_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HAZ9631476.1"
                     /translation="MDSLPVELQALCWNLIDQNVQKQFPLDYLQIFEFSTEKGNQKLV
                     HRQEEPEERKEYLISPKLRLKSVSQKIWAIDSGEYQTMLLPEEY"
     gene            3430..4173
                     /locus_tag="J8S10_002945"
     CDS             3430..4173
                     /locus_tag="J8S10_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631477.1"
                     /translation="MVVSKLPRNEDYLTNYDGYVVTTEHFDLANPVTKVDDIPDYEMY
                     SQTIDSLNKRFGNRVLKGIKIGYIASEKDRIIDYLADKDYDLKLLSVHHNGQFDYLDD
                     EVKDMDPAIVIPQYFAQLSEALVVIEADVFAHFDYGFRVFGLSVAEFKQYEAQFLPIL
                     DQVIKNKLAFELNAKSAYLYDNLALYEYVIDLYLSRGGTLFSVGSDGHYLEHFRFHFD
                     DLFALLKANGVTELAIYQKGKRIMVPLPV"
     gene            complement(4210..4707)
                     /locus_tag="J8S10_002946"
     CDS             complement(4210..4707)
                     /locus_tag="J8S10_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAZ9631478.1"
                     /translation="MNNQITLAYLDYDDLDALQVVSVVSFYESFIDGADPLDMQGYLQ
                     TQLTTEILAVELAQSTSKFIGIKDHQILIGYMKVNDEKDAIEIQRLYLLKDYQNKGLG
                     QRLLDEANRYAKTKQKRYLRLTVYEKNHAGIRFYERHGFKKIGIKHFPLGKQDRICPI
                     LEKEI"
BASE COUNT         1402 a          907 c          694 g         1735 t
ORIGIN      
        1 ttctttgata aataatattt tcaattattt aatcatttga aaattgttag tcattccaat
       61 acgttgagaa attcttccat ctgtataaac acgaaattgt tttccaccag ccatggtcgt
      121 gtttccatca tcatccgtta caatattaat tgaatagtag cttccatttt catcttgcat
      181 tagatctttc atatattcat ttgtgctaat taaattagta tttgatacat ttttatcagg
      241 agaatcatac aaccataaag ctttattatt tagcacagat tctttagcag cttcccaact
      301 tgaaattcct gaactacttg tagattgtgt cgttgtagtt gttgcttgtt gagtagattc
      361 ttctactact ggtgtttgag gagtttgtcc attcacaata tcactgaaac cttgttttaa
      421 ctgttgattt tgagtttcgt taaagtacag ataattattt tcattacctt gattttgttg
      481 cgttaaataa actttaggtt gtccattttg aaaaccgaaa aagtaaacat gctgccctaa
      541 atattctcca gtttctacat cagaataaac tgctactaaa ttgaaatctg catgaccagt
      601 tccatcttct gaccattgta cggtaactgg tgcttcattg attgccattt tccaatcgcc
      661 attaatcacg gcttgtggta aaggagtgcc atacagactt acattattct gaagattgta
      721 gcttttatat tcttgaccta atgtctttcc ccattgtgtg acaaaagttt ctaatttgga
      781 agctttattc gtatcccaca aagtattctt aacctcttca gaagaagatt cagtgattga
      841 acttgcactt gtttccacag attgcttcat ttctgttgta gtttgttcag ttgattgcgt
      901 tttacttttt ttagtctcaa ttgttgtatc agtttctata gtcgctttag tcctcgtatt
      961 ctcagatgta caaccagtga ataaaattcc cattcctatt agtaataaca gccatttttt
     1021 cattatattt ccccctttca atttctccct cacgtactta ttctatcaga caattaattg
     1081 atctaaatgg taatctttta atcgattctt tcccaataat gtcgatagcc cgtatggcag
     1141 cggtctcttc cttgaggact ctcagatgga ttaaaactag tagaaatttc ccttccacat
     1201 cctctacagc gataagttct cattattttt gggctattag tattattttt cttagttaga
     1261 gctatgagtc caactatgat taccccaact gtcttaatta cttttccttt atctatattc
     1321 ggatgcgcaa gcatatattg atataaccaa tatccaccgt aaattaaacc acctaataca
     1381 atcagcttag ccatgtactc gtctcctttc tttttgttta attacttttt gaatccatct
     1441 tgcagagaaa ccataaactt ctgtcaattg acggatatct acagtttttt cctgttctat
     1501 catgttttcg attctttttc taactaactc acgatcgtac attttcattg gaaaagaaat
     1561 ctgttgccct cgaaaagcaa gataaaattg atagagcaat tctgaatcca gttccatttc
     1621 ctcaaaaaag tcattcatac ttttataaga gttactcaaa caagtttcat caatctccat
     1681 ctacacaccc cctgttattt tttacataat gaaaatagca tattactggg tacattgata
     1741 attcatataa catgtatcat cacatgtatt tttaaagtca aaaagcatgt aaaactactt
     1801 ataagtaaca tgagaaaata aaatgttatt tttcttgaaa taataattga ctatctgcca
     1861 attgccattc attacgaaca tgaatactta gtgggtggga taacttacct tctgcattta
     1921 tcaatacttt ggtcatcttc ttttgtttcg cactcaattg atcgtaaata gtctttgctt
     1981 gttcataagc cacttgactc gtcgctgtaa tcgaaccaca agcaaaaata atggtattga
     2041 ttttcttttc tgtaaaaaca gtcgttaata tttccaaaga ttgttcatca tttcctcgaa
     2101 gaaatacccg aggacttttc gcttttgtgt acgaaaaaag attcacagca ataaaaccag
     2161 taaatcctaa ttgtcggata ttcttttcga ttaataacat actcaaatca ttcgtaaatg
     2221 gttctgtatc tgttggacga atagtaatga ctactgctaa tttatcttcc gcttcttttc
     2281 ctttgatcgc ccattgtcgt ttgaaaacat agcgatgggt atgatgagga tctcgccaaa
     2341 cttctgtttg tgtggtcact aattcttttt caatcatctc tttttctcct atgctatttt
     2401 ttgttcaagc acttcaatta ccattgccgt tataagtgtc aatactagtt gaaaatattt
     2461 catattcttt ctcctttttt cttcagaatt tgatgaatcg cggtaaggat atcttctaaa
     2521 catttcgcaa tcattctcaa ataatcgatc ttattcatcc gttcctccaa tctgactcca
     2581 aaccaatcgt ccttctacca gtaacccacg aacaaattct cgctggctgg taatatctgt
     2641 aatgaaataa actacatagt cttttccatc ttctggtgcg caataaatat aaagatgtgt
     2701 catcactaaa cgtggtagat gaacatcttc aggaagcata cccatttcaa tttcctcttt
     2761 ttccatcgta acggattcat agccccactc ttcagaagca gtgaccagct gtgcacactt
     2821 ttccagtact tcgatagccg tttctaacaa gtcctttcgt tcctttcttt tagatactag
     2881 tattcttctg gtaataacat cgtttgatac tcacccgaat caatggccca tattttttga
     2941 gacactgatt tcaaacgaag cttaggtgaa atcagatact cttttctttc ttccggttct
     3001 tcttgacgat gaaccaactt ttgatttcct ttttccgtag aaaattcaaa aatttgaaga
     3061 tagtctaaag gaaattgctt ttgaacgttt tgatcgatta gattccaaca taaagcttgt
     3121 aattccaccg gcaaactgtc cattactccc tttgtgacat aacgttatcc tttattttga
     3181 aacatttctt ttccctcctt tgccataaaa atagcccaat cttctattaa agaagattgg
     3241 gcttcatgga tataatatat atttgtaaat aaagttaatt cagttataat tatcaaaact
     3301 acacaattat taaagttttt catatctctt tgtttagtaa gtttttctaa atcttaaccc
     3361 gtggtgctag ttaatttttt cctagaggaa aatgtctaaa catgttggta aatcaacaaa
     3421 aaaacgcata tagtagtctc aaaactccca agaaatgagg actatttaac aaactacgat
     3481 ggttacgtcg tgacaactga acattttgac ttagccaatc ctgttactaa agtcgatgat
     3541 atccccgatt atgaaatgta cagtcaaaca atcgatagct taaataagcg ttttggcaat
     3601 cgtgttttaa aaggcatcaa aatcggttac atcgcttctg aaaaggatcg gatcatcgac
     3661 tatttagccg ataaagatta cgatttaaaa ttactcagtg tgcatcataa tgggcaattt
     3721 gattatttag atgacgaagt caaagatatg gatcctgcta ttgtgattcc tcagtatttt
     3781 gcacaacttt cagaagcact agttgttata gaagcagatg tctttgctca ttttgactat
     3841 ggttttcggg tatttggtct atccgttgct gaatttaaac aatatgaagc gcagttttta
     3901 ccgattctag atcaagtaat caaaaataaa ttggcattcg aattaaatgc taagagcgct
     3961 tacttgtatg acaatttagc gttatatgaa tatgtcatcg atttatatct ttcacgtggt
     4021 ggtaccttgt ttagtgttgg atcagatggg cattaccttg aacatttccg tttccatttc
     4081 gatgatcttt ttgctctgtt aaaagcaaat ggtgtgacgg aattagcgat ttatcaaaaa
     4141 ggaaagcgaa ttatggttcc attaccagtc taaaaaaacg tcctcagcat caaaagtgag
     4201 gacgtttttt tagatttctt tttctaaaat cggacaaata cgatcttgtt ttcctaaagg
     4261 aaaatgtttg atcccgattt ttttaaatcc atgacgttca taaaaacgaa tacctgcatg
     4321 atttttttca taaacagtca aacgtaaata acgtttttgt ttcgttttag cataacgatt
     4381 cgcttcatcg agtaaccgtt gccctaaccc tttgttttga taatctttga gcagatagag
     4441 ccgttgaatc tctatagcat ctttttcatc attgactttc atataaccaa tgagtatttg
     4501 atgatcctta ataccaataa atttactggt tgactgtgcc aattctactg ccaatatttc
     4561 agttgtcaat tgtgtctgta aatatccttg catatcaagt ggatctgcgc catcgataaa
     4621 cgattcataa aaactgacaa cacttacaac ttgtaaagca tctagatcat cataatctaa
     4681 atacgctagt gtgatttgat tgttcatcta actcctcctt ttgacatagt atactata
//
LOCUS       DADQDV010000137         4731 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.141, whole genome shotgun sequence.
ACCESSION   DADQDV010000137 DADQDV010000000
VERSION     DADQDV010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4731)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4731)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4731
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.141"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(13..1098)
                     /gene="xerS"
                     /locus_tag="J8S10_002947"
     CDS             complement(13..1098)
                     /gene="xerS"
                     /locus_tag="J8S10_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HAZ9631479.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLENNPMDQVATITDKTTLAARAN
                     AIEKKLFLDEDTQNYLDYIANEYKKTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VVNINLEDLSLEKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRVQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHTSTNTTTLYTHIDNAATIDALNAL"
     gene            complement(3174..3692)
                     /locus_tag="J8S10_002948"
     CDS             complement(3174..3692)
                     /locus_tag="J8S10_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HAZ9631480.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
BASE COUNT         1554 a          777 c          717 g         1683 t
ORIGIN      
        1 tttttactac atttacaaag cgttcaaagc atcaattgta gctgcattgt ctatatgagt
       61 atataaagtt gttgtatttg tacttgtatg tcccaattgt tgggcagtta ataccaatga
      121 atttgtctgt tgatagagtc tagtagccaa agtatgacgt aatttatgtg gactgacttg
      181 gactctgaat ccttttgaat attttgctac catccgttcg attgcaatac cggatatacg
      241 cttggcttct ccttgataaa ttgctagaaa taaagctttt tcgttttctg ttactttgta
      301 tcgttctttc cgaatagcta gataattagc taaatattcc attgcaaatg ctgctatatt
      361 tactgcgtct ctcttatttc cttttctagt tactaccaca ttattctttt ctaaagatag
      421 gtcctctaaa ttaatattta caacctcgga gagtcttaat ccagatccta aaatcaatgc
      481 attgatcgcc aggtctcttt ctacatctcg ttgataatag atcaaagctc gtttgctcaa
      541 agttttttta tattcattgg caatataatc tagataattt tgtgtatctt cgtctagaaa
      601 taattttttc tcgattgcgt ttgcacgggc agctaacgta gttttatctg tgatagttgc
      661 tacttgatcc ataggattat tttctaagta tggttttcct aaaggattat tggaactttt
      721 cgaaagatat ttaaatagaa cctttaatgc tgtgatattt ctattgatag tagaagtaga
      781 tagacctaag ttattattat ctttgagctt agtttttgtt gtctcttttt ttacattttc
      841 ctttgtgcga cgtttcaaat gagatttgta caagtttaga tcataggcag ttaactgtct
      901 tatcgaggtg attgaagtat cgggaacgat agactcactc agaagccatt cataaaagag
      961 cttataattt tttagatatt ctaaagtagt tcgaggtgat tgatctttat cctcacgatc
     1021 ttgaacaaaa tcttttatat aatcgggcat atgaagtatg attgtatcta ttttttgata
     1081 tatttctgta tttttcatgt tattcatcct ttcgataagt aggggagagg agtatctcta
     1141 taattggact ataccaatta tagagtgttt tgtcaattgg tatactctga aatttattaa
     1201 tttatttcaa aaaagcagat aaataggtat agatttaata atttaaaata aatggtatac
     1261 atgaatagga aaggaaacag aaggaggcaa tcttaatttt ttaaattgtc taaattatat
     1321 agaaagaaca atctttctat ataattagac ataagagaga ctacggttga tttgatatta
     1381 acaagcgtat atgaatgtat atacaaataa aaaaggggag ggagaagtta aagaaaattc
     1441 agagaagtgg ggcactcagt agtattaaca atttaaaagg aatttcttaa agaaaatggg
     1501 ttgcatcctg gagatacaat ttttttagat aaagaaaaaa ttcaagcaac aattcaaaaa
     1561 aatcttaact gctgagattg atgtagcaat atctcaatca tcaacaaagt acgatcctgc
     1621 ctttcaaaag cttattgata aatgtttatt cattataaaa ataaaagaaa aatttatgtc
     1681 agcttttttc atcaaagtgg taatgataat tcgtctatta attgtatttt ttaggaaata
     1741 tggtataatt gttttaacga aaaggtaatt catgatacac caaaaaccac tagctggcgg
     1801 gctagtggtt ttcttttacg ttctattcag attaacgggt aggcttactg tcttttttgg
     1861 caataatttt gcaatcaagc catttacaga tgtaatgcgc ggatacttct gctaagattg
     1921 caaaaaacat atcgaaaagg taattcataa tacaacctcc tccccttgcc ataataggcc
     1981 ggggtagcag acagcataaa tattatacca taactgaaaa tttcatttta gtacatttca
     2041 atatattgat gaaccagcac aataaaacat gccatgacta acagaaaaaa acttattaaa
     2101 ccagatataa cttgtaaaca tccaactata tagaaaacgt aaattttcta tatagttgga
     2161 ttaagataac gactatttat tttatcatat ttttactata ccctatactt ttacttggta
     2221 tatttatgaa taatcgcaaa tttaccccta tactactagt ttgtaagtta gattaataaa
     2281 aatactaaag ttatttgttc ttttattaaa tacacctaca acttataaat tgatggtatt
     2341 tagataacac gaaagaataa aaataacagc tgatagtaaa gtttgttgac gattgctact
     2401 caatcgaaag tgagttagtg cgtatgaact tgcttctgaa aacttatgaa atgaaagacc
     2461 ttttacatct tgcagaaatc gttactggga ttaaactaag caataaaaac taatgttccc
     2521 ctcattcttt gaacttctac tatttgattt atttattctg ataaatgacg atttcacctt
     2581 caggatcttc aaatcccgta tagaatttat ttaagatctc ttcagtatca gtaataggat
     2641 aggcgatagg ccacataccc tttgatggtt agaataaact gctcaaaatc tgtatcgtat
     2701 gttggcttta gcatattaac aaaggctatc tccaaattat aaaccataag cgttgaatcg
     2761 ttcttaacaa tttcaattct tcctaaccca aagtcagaag atataattac cggacttgcc
     2821 ttacccttca tgtgggttgt tgagattcca tatttaaagg gaattgtcgg tactatcggc
     2881 ggtctgaaaa acatcccaaa aataaaaaaa tctttcccct gctagtctcc taagtccctt
     2941 tgtagcggat atggcaccat aatctcattt tatcgaagtg agtcatggtt tatctgttgg
     3001 ccaaccaaaa ttgatacaat ctaacgatgc accctctacg gcattctagg ggagtgcact
     3061 tgcattcacc caataaaaac cggcagttag caaagaactt atgtagtcgt atgttcttac
     3121 tgttaacata caagaggtct cctttccaca attgcttagc agtaaacggg aatttacaaa
     3181 gctaatctct tccattttct tatctttgtt ctaaaagtcc caaatggagc aactgtattt
     3241 acatgaataa atttatatac ttcccataca gccgttttgg ttgcctcgtc tgcccatttt
     3301 cttttgtgtg cagtgaatag atcttcatca ctcattgaat caatcatcat gttaatatca
     3361 tcaatattac gattgagaat ttcctctaat tctttcaatg gtagatgtgc ataggtattt
     3421 gtaaaccact tatataactc tcctaactga ttccatttaa attgatcaga aggcgtttta
     3481 acagataatc catttctttc atcattttcc cattttagaa ttaaattcgt ccaaccaact
     3541 tgatatgcta aattttcagc aggtgttcta tccacttcct caactctttt atccttcaat
     3601 tcttcaggaa tagtttcaaa ttctaaaata tatttagtat aagtcctatt tatttctttt
     3661 tttaattctt ctttattttt atatgttctc attatattac ctccataaat tcctaattgt
     3721 ctcctttaat tcatctataa tttcatccac gatattttaa tccgttctac aatgcatatc
     3781 tgatatgcat tgactgtcta actcatatgt gaatgattta taaaatatcc caacgtctca
     3841 tctaaagaaa tgttgatcgt cagcaaggag ctaaaaaata cgaatatatt tcttttgtag
     3901 taaaatcgga ctggtttgca tatcattttc ttcgtaaata tcaaaatcat gttaactact
     3961 atcaattact aataaaaact accactttaa gcgttaagaa ctgttaagtt tagttaagtg
     4021 aggatagttc acaaaatcca ttgttaaact tcacgaaagt ggtaaaactc aaaatgcttt
     4081 atataggatt acagcatcgc tctttcttcg attgcgcgtt gggtaaaaaa tattatgaag
     4141 taaaaattga cgatgacacg ttccttacgg ctcatcagat gaaacagcta caaaaacgaa
     4201 atgatcaact cgaagaaaat ttaattctaa aaaagcgatt gccatattca cgcctcgctc
     4261 gacgaactat taaaggtcaa gatttacctg aagatcatcc tttttaggaa attgaagctt
     4321 tttatgttgc acaatgcatt tataatacta caatgatgtt ttcaccagat attcttctag
     4381 ggtgcggtgt aatgaaacag atacacttgc aaaagaaaat tcaccgcgaa tttactaaaa
     4441 ttatgaataa ttatgttaat cttccgaaat ttttttccaa aattaaggga tcaagctggt
     4501 gttatagatt gtttaaggtt ggcaaaaaaa taacttcttt ttaaacaatt atagaaaacc
     4561 gatactctgt taagttggtt gacacggtgt cgatttttat gactttctta ttctgaaact
     4621 tcactaacgg acagtaccta aaaagtctat agtatggacg tttacgagta ctattttatc
     4681 aaaaatgctg ctcatttcaa cttatatgtt ttagtgaact acccccactt a
//
LOCUS       DADQDV010000138         4680 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.142, whole genome shotgun sequence.
ACCESSION   DADQDV010000138 DADQDV010000000
VERSION     DADQDV010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4680)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4680)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4680
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.142"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(12..482)
                     /locus_tag="J8S10_002949"
     CDS             complement(12..482)
                     /locus_tag="J8S10_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HAZ9631481.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(641..1099)
                     /locus_tag="J8S10_002950"
     CDS             complement(641..1099)
                     /locus_tag="J8S10_002950"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HAZ9631482.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            complement(1270..2415)
                     /locus_tag="J8S10_002951"
     CDS             complement(1270..2415)
                     /locus_tag="J8S10_002951"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HAZ9631483.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            complement(2428..3345)
                     /locus_tag="J8S10_002952"
     CDS             complement(2428..3345)
                     /locus_tag="J8S10_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HAZ9631484.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            3773..4336
                     /gene="efp"
                     /locus_tag="J8S10_002953"
     CDS             3773..4336
                     /gene="efp"
                     /locus_tag="J8S10_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HAZ9631485.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
BASE COUNT         1459 a          849 c          881 g         1491 t
ORIGIN      
        1 tttttattaa gttaaagaac ggattcaatt gcagcggtca ttttcaatgg agaagtttgt
       61 ggtgcaaatc gttcgattac tttgccattt ctatcaatca aaaatttagt aaaattccat
      121 tttattgctt tagtgacagt accaggagct tcatttttaa gataagtaaa aagaggatct
      181 gtattttctc catttacgtc aatcaattga tgcataggga aggtaacgcc ataagtggtt
      241 ttacaagctt ctgctgcttc agtcgctgaa tctagctctt gtttaaattg attggaagga
      301 aagcctaaga taaccagacc ttgtgtctga taagcttggt aaagttcttc taattgttta
      361 aattgaggtg ctagaccgca ttttgttgca gtgttaacaa tgattatcgg tttgcctgca
      421 tattttttca atgaatagac agtgccgtct tctaaagtag tttcaaaatt ataaatagac
      481 ataaagtttt ctcctttcta ttttatataa taaaaagagc gctaaactga aaactagcta
      541 tttgttttcc cgtttagaac tcttttcaga caataaatat ttaataaaat acgaagataa
      601 gatagctata ttgcttctca tctttacgtt cttttagaaa ctatgcttct acttcagacc
      661 attcatcgcg ttttgctaaa aattcacgag ccaaagcttg tgcaccttct agtgtatggc
      721 tggcagccca gccacattgt gtttcattgc ttgcaggtac ttcagtagct tcaagaacat
      781 ctttcattgt tgcttcaaga acatctaaaa tgtcttcgta gctttcatga ttcaatacag
      841 tcaagtaaaa gcctgtttgg catcccattg gagaccagtc tacgatgtaa tctgcgtgat
      901 tgcggattag ttcggcagtc aagtgctcaa gtgaatgtag acttggcatg tccatgtgtt
      961 ctttatttgg ttgtttaaag cggacgtcgt atttaatgat gacatcgcca tgcgcacccg
     1021 tttttcgatc agctacacgt acataaggtg ctttgacttt tgtatggtca agattaaaac
     1081 tttcgacatt cattctcatt tgtaagactc ctatctgttt gttcattcgt tttgatgctt
     1141 ttcactaaag aattatttag tgaaatttac aaaaacgtct ttctacttga ttctaacact
     1201 tatcgtttcc aaggtgtagc aatctgaaat attttttaga tttttctgct aagtcgttta
     1261 ttgggacttc tagttcttga ttctgtcaaa tgcctgagct aaatcgttta tgagatcctg
     1321 accatactca attcctacag aaagacggat caagccgtcc tttatgccag cctcttctcg
     1381 tttttctttt ggaatagacg catgagtcat gacagaagga atttccacta aactttctac
     1441 gccacctaaa ctttctgcta aagtaaatag ttggagtgat tcaacaaatg gaatagcaga
     1501 ttcttcattt tttaaagtaa aagaaatcat tccgctaaag ccgctcatct gctgcttagc
     1561 aactccatgg agttcatgat cgggtaatcc tggatagtag accttttcta ctgctggatg
     1621 agaaaataga aaatcagcta ccacaaaagc atttttttga tgttcctcca tacgaacact
     1681 tagtgtcttg attccgcgct gaagtaacca gctatcttgg ggaccaagta cggctccgat
     1741 agcattttgg taaaatccga tctgatcggc tagatcttta tggttagaag tcactaaacc
     1801 agctactaca tcgctgtgtc cgcctagata tttggtaccg ctatggacaa cgatatcaga
     1861 accgagatct aaaggtcttt gaaaataagg agtagcaaat gtattgtcag caataactat
     1921 caatccatgt tgatgagcca gagtggcact tttttctaaa tcagtaatct ttagaagcgg
     1981 attgctaggt gtttcaagat aaagtgcttt tgtattgggt ttgatggatt gttctatttt
     2041 atcaagatta ctcgtatcta tgatcgtgta ctcgagacca tttttagtaa gaactttgtc
     2101 aaatagacgg aatgttcctc catagacatc atctcctaat aagatatgat cgccagcttg
     2161 aaaaagagaa aaaacggcat gaatcccaga aagaccagaa gaaaaagcga atcctcgaac
     2221 accgccttcc aaatcagcaa tcagttcttc caatgcaaaa cgagtaggat taccagatct
     2281 tgaatattca tattgtttag gctggccgac gccatcttgc cgataagtgg atgtttgata
     2341 aataggtaca ctgacagctc ctgttgtggg atcttcactg atgcctccgt ggatcaattt
     2401 tgtttgaatg tgcatgtttc tttcctccta taagtaaatg ttttttgata aatagcggtc
     2461 tgctgcgtct ggaaaaatcg taacgacacg atgaccaggt ggtaaacgac gaatttctct
     2521 taatgctgct gcaaaagccg caccactcga acttccaact aatagtcctt gttctcgtgc
     2581 taactgccta gtatagttaa acccttctac atcagagatt gtctcgatct gattgattga
     2641 aaggggagaa agaaacggcg gaatgaattc tacaccgata ccctcaattt cgtgaggggc
     2701 tggatcacca ccatttaaca cagagccctc tggttctaca ccgattattc gaatgtcggg
     2761 atatttttct ttcaaaaagg tagaagttcc agcaaaggtt ccaccactcc caattcctgc
     2821 tacaaaacta tggatatttt ctttgatttc atgaaagatt tctggcccta acgtatgata
     2881 gtaagcagca ggattatctt tattttcaaa ttgaagaggc agatagctgt ttgatatctc
     2941 ctctgcaagt tttttacttt tgctgatggc accgatgatt ccttgctcac taggagaatg
     3001 gatgatcttt gctcccaatg ctttcatcaa ttgttgtttt tctaagctaa acttctctgg
     3061 aacaacaaaa accgttctta atttgtatgt gagtgcggcc agagcgatcc caattcctgt
     3121 atttccggca gttggttcga tgatcgtcgt tttttcattg atttttcctt gggcaaatcc
     3181 ttctttgatc aaataactgc ccaatctatc tttgatactt cctccaggat ttaaatattc
     3241 tagttttgca taaatagcag aacctttagg catagaatag tgctgattgt caaagcgata
     3301 aagcggtgtg gaaccaatag cttctgtaat tgtcgagata atcatgtggg cctcctaaaa
     3361 aaagataata aaaaaaggag ctgactatta aatcagctcc ttgaaagaca tagagaaaaa
     3421 ttgagtagat aaaaagataa gttacctggt actcattcta tgaagggcaa ttaatagaca
     3481 tgacaaatag tatgctgctt ttatgcacca tacaacagca acgattcaat tgtttttggt
     3541 tgctgactgt catgtgtatc cctccaagta aaatttttat taacgatagc atgaaaaaaa
     3601 ataaaagtca aaggcttgaa agaaaaaaat atttcgatag catcgtttac ccgtgtttat
     3661 ttttctgaca aataggcatg agaccttaaa agatagagaa tactctagtt ttctggccgg
     3721 ttgtctgata caataaagtt gattatgata aagaaaagaa ggagcaaaaa taatgatctc
     3781 agcaagtgat ttaagagccg gtatgacttt cgtacaagac ggcaaactga ttaaagttct
     3841 ggatgcaagc caccataaac ctggtaaagg aaatacagtt atgcgtatga aactgaaaga
     3901 tgtccgttca ggtgcaacat acgacacaac gttcagacca gaagaaaaat ttgaaaaagc
     3961 acatatcgac acaaaacctg tacaatattt gtacacgatg gatgatacag ctttcttcat
     4021 ggatttggaa acatatgagc aatatgaaat tcctgtagaa acagtagaag aagaaatgaa
     4081 atatatccta gaaaacatgg aagtaaaaat ccaatttttc ggtagcgaag tcatcggcgt
     4141 tcaattacca acaactgtcg tattacgtgt tgtggaaaca caaccttcca tcaaaggtgc
     4201 aacagtcact ggttcaggta agccagcgac aatggaaact ggcttagtag tcaatgttcc
     4261 tgacttcatc gaaacagatg aattgttgga aatcaataca gcagaaggtt cttatgtaaa
     4321 acgtgcgtca aaataattcg ctaacggatt gataagaatt tgaaaacaga gcttgacctc
     4381 ttgaaaggca gatcatcgga tctgcctttc aagaggtttt ttgtggaatc agcaaattga
     4441 aaaataaaaa agtatttgat tttatttata ttttgaaaga tgaatggcaa aagctagaga
     4501 aagaaaaaac tgcacttatt tatgaagaaa ttgaaatgat tcataaaatt gaaaatatcc
     4561 gaactattcc gaactatatt gaagcgaaaa tattttttca tcactaaata gtgttgaatt
     4621 tatgttttta tgtataaata gcttctaata gttcgggtat tttgttttta taaccatttt
//
LOCUS       DADQDV010000139         4587 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.144, whole genome shotgun sequence.
ACCESSION   DADQDV010000139 DADQDV010000000
VERSION     DADQDV010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4587
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.144"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            186..2855
                     /locus_tag="J8S10_002954"
     CDS             186..2855
                     /locus_tag="J8S10_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HAZ9631486.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEVSFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEKPRNTHRRRRRK"
     gene            complement(2946..3566)
                     /locus_tag="J8S10_002955"
     CDS             complement(2946..3566)
                     /locus_tag="J8S10_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAZ9631487.1"
                     /translation="MFLINATDEILSVNKVFYTVPAEKMSRVSSDINTITSRIGLTKA
                     MHMVLKYNQEDPPVPKTYEAIDLIIVDEIDRLKLQHLEQLRDIYDRNDLAMVLIGMPG
                     IEKRLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWADLGIDIKLEDFSDYEAITTI
                     IKITKGNFRLIHRLFAQIDRILRINQMDKITVEVVEAARDSLVIGI"
     gene            3680..4051
                     /locus_tag="J8S10_002956"
     CDS             3680..4051
                     /locus_tag="J8S10_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631488.1"
                     /translation="MKKLFSALFILLFGFIGIGTSGNIVKASTMVEQTSEMAKTFSQL
                     TPEEQSYFKSKGFSDKDTFYTQKIEPQDPKTRFSANVLRLTASTKKITNTQGRTEYII
                     TSPNSAMYRISTRLSLGSAKS"
     gene            4216..4554
                     /locus_tag="J8S10_002957"
     CDS             4216..4554
                     /locus_tag="J8S10_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenic metallochaperone ArsD family protein"
                     /protein_id="HAZ9631489.1"
                     /translation="MIISYYVLNRSDDEGLFVFQSLHEDTMLKEFYNRIKNKQIETNL
                     YFLSDSILPFISNPKILNLLQTKDLKSLPIIVIDEEIVKYGAYLSVEELEKLTNIGMS
                     IQEDNGVHGT"
BASE COUNT         1419 a          790 c          861 g         1517 t
ORIGIN      
        1 atttttaagg gtgggacttt tgattcctac cctttttttg cgtttatttt tgttatacga
       61 acaaattatg aagttattta ttctaaattt tatttttttg tgaaaattag actcttttta
      121 agcagagaaa aacaaggata tgataaactg aatacaactt catagaaatt tggtggaaaa
      181 taaatatgaa aaaaaattta aagtcattct ttagagaaaa cggacgctac gcagcagcta
      241 gtttcctgat tccgtttttg attttagcac ttgtttatct aagtatcggg atctatcctg
      301 gaagcagcag aagtattttg gcaagtgatg ccttttcaca gttttctaat tttcatgcca
      361 gcttccgaaa tgttcttctt ggaaagcaaa gtatttttta tacatggaat gcttctctag
      421 gattgaatta tttatcttta atttcttact atctaggcgg gatcttcacg ccactggtgt
      481 tcttttttcc aaaccagatg atgccagatg cactgtatgt tctgactttg cttaaggtcg
      541 gctgtgccgg attggctttt tggtttcttg cacgtacgtt caagattcct cgctgggggc
      601 atgttgcact tagcgtcagt tacgcattga tctcatttat cactgcacat tcggagatca
      661 tcatgtggct ggatgcattt gtttatcttc cattagtgat tttggggatt catcgtgtta
      721 tggatcttaa acggccgaaa cttttattta tcagttattt actcttgttt ttatccagtt
      781 tttatatggg ttttatgatt ggcgtatttt ctttcttata ttttatcgcc cgtctattga
      841 caaactggtc agaatataaa aaaacgattg ttccttatgg tatcacttct ttactggcag
      901 gcggcgcttc aatgatcatt gtattgccag cagtgctgga tcttcggtca aatggcgagg
      961 cactgagtca gatcactacg ttgaaaacag aagcgacttc ttatctggat ctaatcatga
     1021 aaaatatgat tggtgtttat gacacgacaa aatacggatc gattccgttc gtttacgcag
     1081 gtctgctacc attagtcctc tgtctgtttt attttgccag tcggaaagta ccgttgaaaa
     1141 ataaattttt gtacggcagt cttttcgcca tacttatcgc aagtttctat cttgttccat
     1201 tgaatttgtt ctggcatggt atgcatgcac cgaatatgtt tttattccgt tatgcctatc
     1261 tgttctcttt cttagtgctc ctgcttgcag gaaaaggatg ggaaaagata gaacaagacg
     1321 atcgtgggct gttgttagga atcattttgg tcgtagctgc tctctttgcg gtggcatggg
     1381 gcatcaaacc tgaaggaagc tacacctatg tgacgatgac ttcctttgta ttgacagtgg
     1441 ttttcttagg gatttatgct tttgctgtgg gattttatca gcataaaaaa ctttcattca
     1501 atcatctgag tatattgtta ttattgatca tgtctgctga agcactggtc aatacgaaca
     1561 gtatgatcca tggcattctt gatgattgga attatgcttc ccgcagttta tatactgatc
     1621 cttatcctga cttgaaagct cttgtaaatg aaacaaaaaa agattccgac tcgttttacc
     1681 gcttggaaaa tctggatcca gtatctgcaa acgattcgat caactatggt tacagtggta
     1741 tcagtttgtt ttcttctata agaaatcgta attcttcctc ttacctggat aaattaggtt
     1801 tccgttcaag agggacaaat ttgaatatcc gttataacaa taatactttg ctaatggatg
     1861 ggtttacagg aatcaaatat aacatttcta aaaacgaaag cacgttcagt aaatatggct
     1921 tccgccaagc tggtcaaagt ggcgactata cactgtatca gaatgtcaat gcattgccac
     1981 tagcatttac tgcaccgttg tccgttaatg atgttgagca gccagtgaca gataatttga
     2041 ccagtcagac aaacttgatc aatacattgt ctggtttaaa tgaacagtat tttacattct
     2101 atacacctac tttgaagaat cagttgaata cgacgatcac aaagacaacg actggcgtca
     2161 cttactcaga aacagcagat aaccagccaa aagagctcac ttgggaagtc catgtgcctg
     2221 caaatacaca agcttactta agtttgttcc caaccaattt tgcacaatta gaaagttcta
     2281 gtgcgacgat cactgtcaat ggtacatcgc gaaaaacgca aatcaacatt tctggtcaat
     2341 actatgatct tggctattat cctcaagaga caacagtgac atttactgca agtttttatg
     2401 gaacgaaaga agtaagtttc atggagccta aagtcgttgg tctagatgtt gtagcctatc
     2461 aagccgcaat gaatcagatc aaagaaaaag gtgtcgaaat ggaagccact ggcagaaaag
     2521 cttctgggac tgtaaatacc gctgaagatt ccatgttggt gacaactatt ccttatgaca
     2581 aaggatggaa agctaaaatt gatgggaaac cagtcaaggt cagcaatttc aaagacgcat
     2641 tcttgatgat aaaagttcca gcaggtaaac atactgtcac tttcagttac ttgcctgaag
     2701 gatttacgat aggtgcaatc ctttttgtcc tatgtattgc attgtttatt ctttatgtct
     2761 ggtaccttga ccgcaatcgc cccttttatg gcacgattga tccagcaata gaagaaaaac
     2821 cgcgaaatac acacagaaga agacgaagaa aataaagaaa cgatggaatc tgtgtcactc
     2881 ttctatttaa atggcaaaaa tttcaatctt taaatgacaa aaaccacctg atttttggtg
     2941 gttttttata tacctatgac taaactatct cttgctgctt cgacaacttc tacagtgatc
     3001 ttatccattt gattgattct taaaatccga tcaatctgcg caaataaacg atgaataagc
     3061 ctaaaatttc cttttgtgat cttaatgata gttgtgatag cctcataatc agaaaaatct
     3121 tctagcttga tatcaattcc taaatctgcc catttgtatt ccaaaatatg atgtgtttcg
     3181 tccttactaa ggttatcaaa ttcatgtgca aatcctatgc gagagtaaag ctgcggataa
     3241 cgagacaatc ttttttcaat accaggcata ccgataagaa ccattgccag atcatttcta
     3301 tcgtaaatat ctcttagctg ttctaaatgc tgaagcttta aacgatcaat ttcatcgaca
     3361 ataattaagt caattgcttc ataggtttta ggcacaggag gatcttcttg attgtatttt
     3421 agtaccatat gcattgcttt agtcagacct attctactag ttattgtgtt aatatccgaa
     3481 ctgacacgag acatcttttc agctggtaca gtataaaaaa ctttatttac acttaatatt
     3541 tcatctgttg catttatcaa gaacaagaaa aagtctgaat attcaaaaaa aataacggtg
     3601 tacattttta aaaggagatg tataatcgag atttagaaag cgttttcctc aaaatttaat
     3661 gaattaggaa gtgattacta tgaaaaaatt atttagcgca ctttttattc tgttatttgg
     3721 ctttattggt attgggactt ctggaaatat agttaaagct agcacgatgg ttgaacaaac
     3781 aagtgaaatg gcaaaaactt ttagtcaatt aacaccagaa gaacaaagtt acttcaaatc
     3841 caaaggattt agtgataaag atacttttta cactcaaaag atagagcctc aagatccgaa
     3901 aacacgtttt tctgcaaatg tattgcggtt aaccgcatct actaaaaaaa ttactaatac
     3961 gcaggggcgg acagaatata ttataacaag tcccaattcg gcgatgtatc gtatttctac
     4021 acgcttgagt ttaggtagtg caaaatcata gactcaaaca gtaaatctag ctaattctta
     4081 tggttatggt ggaggaatgt attttacatt tactgggaaa agacaatatt acagtgtaaa
     4141 attagctatg caagtttata atacatttgg tgtagggtca gtctcttgca ctgcgggagg
     4201 attgacaata ggaaaatgat aatttcttac tatgtcttaa atagaagtga tgatgaagga
     4261 ctcttcgttt ttcaatcatt acatgaggat acgatgctaa aagagtttta taatcggatt
     4321 aagaataaac agatagaaac aaatttatat tttttaagtg actctatctt gccttttatt
     4381 agcaacccta aaattcttaa cttgttgcag acaaaagatt tgaaaagttt accgattatt
     4441 gtcattgatg aggaaattgt aaaatatggc gcttatctaa gcgtagaaga attagaaaaa
     4501 ttaactaaca ttggaatgag tattcaggag gataatgggg tacatggaac atagaatgaa
     4561 tatgcacagt tgagaacgga atttgac
//
LOCUS       DADQDV010000140         4548 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.145, whole genome shotgun sequence.
ACCESSION   DADQDV010000140 DADQDV010000000
VERSION     DADQDV010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4548)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4548)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4548
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.145"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            82..1031
                     /locus_tag="J8S10_002958"
                     /pseudo
     CDS             82..1031
                     /locus_tag="J8S10_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300609.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
     gene            complement(1076..1709)
                     /locus_tag="J8S10_002959"
                     /pseudo
     CDS             complement(1076..1709)
                     /locus_tag="J8S10_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
     gene            complement(1969..2517)
                     /locus_tag="J8S10_002960"
     CDS             complement(1969..2517)
                     /locus_tag="J8S10_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631490.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            complement(2518..3375)
                     /locus_tag="J8S10_002961"
     CDS             complement(2518..3375)
                     /locus_tag="J8S10_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAZ9631491.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYVEVE"
     gene            complement(3661..3948)
                     /locus_tag="J8S10_002962"
     CDS             complement(3661..3948)
                     /locus_tag="J8S10_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAZ9631492.1"
                     /translation="MAYEIVPSKHVIKYLKKLKEKPLKEKFLNLIYDEIAIDPYKGEQ
                     KTGDLSGIWSSGFKYAGTTYRVAYEIIENKVIPVLLCGTHENFYEQLKKLI"
     gene            complement(3938..4267)
                     /locus_tag="J8S10_002963"
     CDS             complement(3938..4267)
                     /locus_tag="J8S10_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAZ9631493.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            complement(4344..4490)
                     /locus_tag="J8S10_002964"
                     /pseudo
     CDS             complement(4344..4490)
                     /locus_tag="J8S10_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
BASE COUNT         1379 a          877 c          658 g         1634 t
ORIGIN      
        1 aagaggacag catatcgata ttgcttcctt ttttttgcta tttatttaag ggatagaagt
       61 ttagaaagga ctgtttataa gatgaaaaat gatatagtga cttatgcaaa cacaaaatgt
      121 gaagaaattg gcatcagtaa tttagaagag tgcttttttg acacaaatga cctgtcgcaa
      181 tttttaagaa cgggaagaac aaatgccagt aaacttgcca atgacttagt tgcaaagaac
      241 gttctattta aaatcaatac tcgtccagtg ttatttgcca tcaaagagcg ctttgaagag
      301 cactttttga ttccggtaaa agatgtatac gaaagtatat ctgaattaaa aacagacttg
      361 gagcccaatt ctacagattc cattctacaa aagatgattg ggtatgatat gagcttatcc
      421 gatgcggtgg aacaaatgaa aactgctgtc ttctatcctg gaagagggct tcctatgatg
      481 atcactggag atactggagt tggaaaaagt ttttttgttc atactgctta tcagtttatg
      541 aaaaaagtga acgttattca tgagaatgct ccttttaaag tacttaattg tgcgcaatac
      601 cataataatc ctgaattatt gtcggggata ctatttggct atgttaaagg tgcttttacc
      661 ggcgcagatg aagatcgaaa tggattgttg caagatgcag acggtggagt actgttttta
      721 gacgaagtac acagattgcc tcctgaaggg caagagaaac tatttgttta tatggatggc
      781 ggaacttatt ctagagtcgg tgaaactatc catcacgcct ccaatgtacg tttagttttt
      841 gcgactacag aaggcaaaga ggattttctg gaaaccttta tgcgaagaat ccctatacat
      901 atccatatcc caaatattga ggaacgaggt attttagaaa aaaacaaatt atcgaaaata
      961 ctctctttag cgaaagcaaa aactttagca aggctattga tgtttctcct aaagtcacta
     1021 gtgttgcata aatatagtca gaatattctg aattattatt ttcttgaaaa aagtaaaaaa
     1081 aatcgtatcc caaactttca tctacatttc cagaaagatc ttcatgttga taatcaattc
     1141 ctgaatcaat gaccgctacc ttcacatcct tagaaccctt ggtttcttcc caagcggatg
     1201 gcatgctaat ctctcttaaa ttagcttgtt tactccaatt aggatcgtta tcgatttcct
     1261 aaagaatcag ttgtatttgg ctcctcaaca tcattcaacg gctctagttc aaccacatag
     1321 tttggctctg cataattgac catatcagaa gcattaaatg ttcttactgc ctcttccaca
     1381 ctaatttctt cgttcaattt cactaataat acttgatctc gcttattata atcgctttca
     1441 tttgtcctaa gagtcaaatc tttttccacc ataactttta cacccaataa attttgcggt
     1501 ttatttttct ctgttgaaat tctttgtgta gcctttaaac tgacaattag ctcattgggt
     1561 acatactcta tttgagagtc atctaattgg ctcataatcc tttctttttg gttagtatct
     1621 gcagttactt gtttagtatg agccatgaac ccaaacatac tcaccccaac aaccaatcct
     1681 aaatatattt tctttttaaa ctttttcatc tacatctcct cctaatagtt ttattttaga
     1741 gttagctcta ttacttattt actaactcaa caacagatta tcatacactt attaatgaaa
     1801 tcacaatatc tcattaaaac acaccctaaa atcataaccg ttcctatgct cattttttgg
     1861 attttttaat cacgtaacca gaaaaataaa tcccctctat ttcacgcaaa tcaaagaaga
     1921 actaagtaac taccgtttaa aggtagttac ttagttcttc tttgattatt atctaacttt
     1981 attattcatt ccccaccctt tgcgcagtga gtcttcggta tcttgtttta tctgactggt
     2041 agttcttatt atttctccac gatcatctaa ttctggaaca attggatatt tttctctgaa
     2101 caagtctagt tctttcacca cgtcattaaa caaatcttgt ttatcttctt gcgtaagatt
     2161 ctgtttaata tactcatcta aagcttttct aagcaattca tctcttgtca tattagtctc
     2221 atacttttct actaaaactc tggaagtcgc atttaacaaa gtcgacagtt ttaaaggatg
     2281 cttggtggaa taaaccttat caaactttct gattggtgcg ccaacttttt ttgttcttcc
     2341 tctactctgt ctttcaacat tggaggaagt ttttatttct tgaacttggt gcacttctaa
     2401 ttgcttattt tcagatggtg taattgcttg ctgctttttc tttgcttctg cttctttttt
     2461 tattttggcg agtcctttgt tgttcccaaa aatatcaagt cctttgatgt cagccaatta
     2521 ctccacctcc acataccaat tctcgtgttc ttccaattct ttcaaaatac tgataaataa
     2581 ttcgtggctt ttgcgatccc attgttttaa gagacctttc tttgtcttct ccatcgtaat
     2641 acctgatccg tcgtatcgtt ttaagcgcgc atttttgagt acaacatttt taatcaaatg
     2701 ttccccataa atctcttggg cttgtttata catttcctga tctactgcgt caccgctttc
     2761 caacatgaaa ggaataacac cagcaacata taaatttgta tcaaattctt tcacaaaaaa
     2821 gtccatatac tcaagatatt gcatcgcatt tctcatcgat tttacttggg tctgtaagac
     2881 gacgattgcc caatccgcaa tgtacatcgc ggatttacta tatacagaaa tagaaggtgg
     2941 gacatctaaa tagatgacgt caaactcatc aaataatggt tctagctttt ctttcatata
     3001 tttgaattgg gataatgaat cattatattg gtctttgatc caatcatcat acatttcaaa
     3061 ggacatgtct gctggaagta tatagaggtt attgattact ttatagacag cctctttagg
     3121 tggaagattg tttatcaaca cgtcagtcac agtattttcg taaacaatcg gttcaccttc
     3181 tccgcctcct tcttcgttag tgaagttcat atgcgttaag ttcatcacat cagaagtatt
     3241 tccttgcata tccaagtcaa ttatcaaggt tctttttcct tcattaactg ctgattcaaa
     3301 ccctaacatt tgcgcgcacg tacttttacc tacgccacct ttaaaattac cgattacata
     3361 tttcttcgct accacgttcc tacctctttt cttttagcaa tattcatttg atactattat
     3421 aacatattta tttttagtta ctaccaaaaa aaagatatat atgtactacc ttataattaa
     3481 taagtaaaag gtagtacata aataaggaaa agctgaaata tattgattta tagctttcct
     3541 caaagtaatg acgttattta atttatcgag aagcagagaa tactcgcgac tttagtcatg
     3601 tagacgaatc agattttcga taaaaaagaa gccgtccttc ttaagaacga caacaaatca
     3661 ctagattaat tttttcaact gttcataaaa gttttcatgc gttccacata acaatactgg
     3721 aataaccttg ttttctataa tctcgtaagc tactctatat gttgtgcccg catatttgaa
     3781 cccactagac caaatacctg ataaatcccc agttttttgt tcacccttat atggatcaat
     3841 cgcaatttca tcataaatta aattcaaaaa tttttctttc aatggcttct cttttagctt
     3901 ttttaaatac ttaatgacat gttttgaagg aacgatttca taagccaatt tctgttgcca
     3961 actcctcttt agtcattact ttagaattag taagtgtatc ttcagcaata tctctaaagg
     4021 aagaatgcat tttgtttttt ctattcttaa attctacaag aatctcatct ttatcgtagc
     4081 cttctgcaat tatatcagac aaaatatctt cgctaaaatc ataaaattct ttttgtggtt
     4141 caacaaattc ataaagaata ccattctcta ccaactttgc ttcaacttcg actccattag
     4201 gaacattaaa atctttaggt actgtcaaca tgattgaatt gccttgtttt cttgtttttg
     4261 taatcattta aatccctcat ttctaacagt atgtaattac ttagtaaata cattatacca
     4321 cgagataatg tatttacaag taattactgt gactcgtaat gcgtccttgc tgaataaatt
     4381 tcaaccacgt gttcatcttc atctacctta taaacaaccc ggtgttgtct attcaatctt
     4441 ctaaaatacc taccttcatg tgtaggtttt aacttctcaa atgattgggt tctgttgcaa
     4501 agttttaaat aaagaataaa atcccttacg gtatctatga tttaagct
//
LOCUS       DADQDV010000141         4503 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.146, whole genome shotgun sequence.
ACCESSION   DADQDV010000141 DADQDV010000000
VERSION     DADQDV010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4503
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.146"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(28..963)
                     /gene="murB"
                     /locus_tag="J8S10_002965"
     CDS             complement(28..963)
                     /gene="murB"
                     /locus_tag="J8S10_002965"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HAZ9631494.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(1036..1956)
                     /locus_tag="J8S10_002966"
     CDS             complement(1036..1956)
                     /locus_tag="J8S10_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAZ9631495.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            2069..2821
                     /gene="xth"
                     /locus_tag="J8S10_002967"
     CDS             2069..2821
                     /gene="xth"
                     /locus_tag="J8S10_002967"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HAZ9631496.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            3685..4218
                     /locus_tag="J8S10_002968"
     CDS             3685..4218
                     /locus_tag="J8S10_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HAZ9631497.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
BASE COUNT         1330 a          879 c          800 g         1494 t
ORIGIN      
        1 tttacttatt ttaagttcca ttacttatta attggctaaa cttctgcttg tttctgatat
       61 tgcttgtttt tctccaatga tccgcacttc tgtttctaaa gacacatcaa atttttcttt
      121 gattacttct tggatgtgcg caatcaattc aatataatct gtcgctgtcg catgatcgat
      181 attgacgatg aatccagcat gtttttcaga gacttgtgca ccgccccatt tcaggccttg
      241 caatcctgct tgttggatca gctgacctgt atagtgtcct actgggcgct taaagacact
      301 tccgcatgaa gggtattcta atggctgttt tgattgacgc aattcggtca actcatccat
      361 tcttgctttg attgcttcat aatcccctgt ttgcaaactg aatcgagctt ccaatacgat
      421 agcacgtaat tcttggactt tactgtgacg ataagaaaat accatttcgt cttttgtcaa
      481 agttttcaat gttccatctt caagcaaaag atccacttca gcaaaaacat ctttgatctc
      541 tccgccatac gcacctgcat tcatataaac cgctccaccg acacttcccg ggatgccgca
      601 agcaaattca aatccagtca atgattctgc caaagctgca taagtcgtat caatcagtga
      661 ggcacctgct tccgcaatga ccatcgttcc tttgacatga atctgtttca tttcagtcag
      721 catgatgact acaccgcgaa tcccgccatc ttgaacgatc agattgcttg catttcctaa
      781 taccatccaa ggtatatcat ggattcggca ataatcgatg atttgcttta cttcttcttg
      841 ttttttcggg aatgcaagga catcagctgg tccacctgtt ttcgtaaacg tatagttcat
      901 caatggttca tcaaacaata tagtaatcgt ggctaagctt tcaactattt cttctttatt
      961 cactgaggat tttcctttct tttctcaaac gtcctcatta ttctatcacg cttaatacaa
     1021 tcttgccagt cttgttcaaa gttgatgacg gtagtgatct ttaagcactt cctcacataa
     1081 ttcatgactt cttacaactt ctttttgttt aagcaattct gtttccgatt tacctaaacg
     1141 gatctgagaa aagaaggcct ctaccattgg ctcaaacccg cgtttgacta gcgtgtttgt
     1201 ccagtcgcca aattctttca ctttttttcc atcagcatct tgaatgacaa gctgggtcag
     1261 atcgtttact tcataagtac catttttact tgttacttga tatttttcta tattagcgcc
     1321 acttgctaaa tccatcgtta aaatagccgt ttgattttgt gtttctaatt gtaaaatggc
     1381 atattccaaa aattcctttg tttctcttat ctggtatttt gttctcaaaa tgggttcatc
     1441 taataaatac acagctgtat caataagatg taaaaacaaa tcataaagga cgaactctgt
     1501 cgtttctttt gccgctattc gatttttttg caggtggatc aaccgcttat ctgggatacg
     1561 tttcaattct tctaccatag gagcaaagcg ccggttgaaa ccgatcatca aaattatttg
     1621 gttcttatca gctaattctt gcaattcacg aacttcattt agatggacac tcagtggttt
     1681 gtcaatataa acatggatac cattttctag acattttttg gctaattcat aatgtacttt
     1741 tgttgctgcg tggatcatac atgcttcgat tttttcttct aaaagctcat cgatcgtttc
     1801 atatagatgt tggaacccgt actctttttg aattctttct tttgtttctt tatttcttgt
     1861 tgcaaaataa aaatcaagtg ttccttgttt tttcgcataa gttggtaaat atgctttttc
     1921 tgcgatattc cctacaccga ttacaccaat cttcatctac tttcctcctg gatcatttag
     1981 ttactttcat cttacaccat tttttactaa aatgaggtac aatagtatcg caaaggtaag
     2041 gaaattaatt cgaaggagtg tgcttttatt gaaatttatc tcttggaacg taaacgggct
     2101 tcgtgccatc gtaaataaaa attttttaga agtttttcat gagttagacg ccgatttttt
     2161 ctgtctgcag gaaacgaaac tccaagcagg acaaattgat ttagatcttc caggttatta
     2221 tcaatattgg aattacgcgg aacgaaaagg ctattccggc acagcgattt ttgctaaaaa
     2281 accagcattg aatgccactt acggaatggg tatcgatatc catgatacag aaggccgtct
     2341 gattactttg gaatattccg atttctttct tgtaacctgt tacacgccaa attctcaaag
     2401 cgaattaaaa cgtttagatt accgattaga atgggaagaa gccttttata attatttgga
     2461 aaatctaaaa aaacaaaaac cagtcatcgt gtgtggggat ctaaatgtcg ctcatcaaaa
     2521 gattgatttg aaaaactgga aaacgaatca aaaaaatgct ggattcactc cagaagaaag
     2581 agcggctctt tctcgactgt tggataacgg gtttatcgat acattccgtt atttttatcc
     2641 aacccaggaa ggtgtctact cttggtggaa ctaccgattc aattcaagga aaaacaatgc
     2701 tggttggcgg atcgattact ttttgacgag caaagattta gagccaggac tagctgatgc
     2761 aaagatccat acggacatta tgggcagtga tcattgtcca gtagaattag atttgaaata
     2821 aagaggttgt gaaaaagtcg tttagtttcg agtattaaga aaaattttgt gaaaatggct
     2881 ttccacattt tgcataaatt tggcataata ccgagaaact ggcttttgaa cactgtttat
     2941 cgagagattg tgaaaaagct gtcctgcatc aagtaataag aacagccaaa caaaaatagt
     3001 tcctcatatt tttcgtttgg ttgggcttat taccgcagat acaagctttt gaacaccgtt
     3061 tattaagagg ttgtgaaaaa gctgcactgc atcaagtaat aagaacagcc aaacaaaaat
     3121 agttcctcat atttttcgtt tggttgggct tattaccgca gatgcaagct tttgaacacc
     3181 gtttattaag aggttgtgaa aaagctgcac tgcatcaagt aataagaaca gccaaacaaa
     3241 aatagttcct catatttttc gtttggttgg acttattacc gcagatgcaa gcttttgaac
     3301 accgtttatt gagaagttgt gaaatcagcg tcctgacctg agtattagag aaacaaatgg
     3361 caaaatagtt cctcatattt tgctattttt tgagctaata ccgagggtca gctgattgaa
     3421 caccgtttag tggagaagtt gtgaaaaagt cgcctacttt cgagtcgtaa gaaatttttt
     3481 tgaaaatggt tcctcacaac tttgcataaa tttgacttaa taccgagaag tcatgatccc
     3541 catctaactc caaatcacaa ggaatgagtt caaaaactag cttttctcaa caaatattac
     3601 ataaaaaatt ctatgttttt tgttaaattt atttgctttt ttcaaaagta tgttacagta
     3661 atttcccaag gaggttttac agaaatgaat tttgttgcca tggattttga aactgccaat
     3721 catcagcctt atagtgcttg ttctcttgcg ctagtcatgg taaaaaatag ccagatcgtt
     3781 gatgaattct atacattgat acagcctgag actccttttt tctggcgaaa tgtccaaatt
     3841 cacggaatcc atcaagaaga cgtacgcaat gcgccgaaat tcccagaagt ctggcaaact
     3901 atccaaccat attttcaaaa aaatcgttta gtcgttgcac ataatgctgc ttttgataca
     3961 aaggtcttag cgggatgctt agattattat catcttgaac agcctaatta tctttcttta
     4021 tgtacagtga aaagtagccg tcgcctgttt cctgaatttc caaatcatcg attgaacact
     4081 gtgtgcgaaa atttgaacat ccaattagat catcaccatg atgcattgga agatagtcgt
     4141 gcatgtgcgg aaatcctgct ttatcaagaa aaaaaattcg ggacagatcc attgaaaaaa
     4201 cttgtgacta taaagtaaaa gaatacttat gaaacacaca aagaggtcgt gagcctgccg
     4261 tttcactccg agtcacaagg agcaatttca aaaaatagct tctcatgttt attaaatatt
     4321 gtgactggtg accgaggagc tggcaggaga acaccgttta ttggagaggt tgtgaaaaag
     4381 ctgttctgca tcaagtaata agaacagcca aacaaaaata gcttctcata tttttcattt
     4441 ggttggactt attaccgcag atgcaagctt ttggacaccg tttaccaaga ggttgtgaaa
     4501 tca
//
LOCUS       DADQDV010000142         4477 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.147, whole genome shotgun sequence.
ACCESSION   DADQDV010000142 DADQDV010000000
VERSION     DADQDV010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4477)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4477)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4477
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.147"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(832..1125)
                     /locus_tag="J8S10_002969"
     CDS             complement(832..1125)
                     /locus_tag="J8S10_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HAZ9631498.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            complement(1528..2706)
                     /locus_tag="J8S10_002970"
     CDS             complement(1528..2706)
                     /locus_tag="J8S10_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAZ9631499.1"
                     /translation="MEKTDRFKKQISSTGRITWYFQAYRTTRRGFNSKREAQLAYLEM
                     EKQQRLKKKIVASNDKFSVVGEQWFQYYRSLNEQKEITYDKREEQLKIIVRWIGDKKL
                     SDLTPECLQELLFTLKECGVNGTNVGYAKNSLQSLIQVLNMIFKYCQRKNLISENPMK
                     SVRMPKYQLTVTDLKEAINNIEDKFLTVDELRTFLNYGIVHEELPMSVLFHVLFYTGC
                     RVSEALALQPGDIDFKRNEILFYKQTAVKGKSKDFRIETTKTVSSARRVLVTPLVMEK
                     LQQLIKALGEMRQHYRFIIEETYLFVYLDSSKRGVPYRREYVNDHVKRCVNRSGINKP
                     FHTHLARHTMASLVAEHCSWEVLKDRLGHTDQTTSKIYRHLTSNEKVKPLIAFSSLES
                     "
     gene            complement(2810..3124)
                     /locus_tag="J8S10_002971"
     CDS             complement(2810..3124)
                     /locus_tag="J8S10_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAZ9631500.1"
                     /translation="MELEVKTNVNSLEIEFYSILQKKLEDYTEKLLAVSHLPLVLTNT
                     DLKRLFQISDSTLNRLVKLGEFPPCWYGIRGHYFRDDVLEWMRKSDSNDYREKLRLLR
                     SL"
     gene            3231..3446
                     /locus_tag="J8S10_002972"
     CDS             3231..3446
                     /locus_tag="J8S10_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631501.1"
                     /translation="MKQGIADIKIIKEILEKSTANAIAFGTGINLSTVKKLKSGERAE
                     EKLNLADAIKITEFGMKNMPTKIEIWK"
     gene            complement(3746..3988)
                     /locus_tag="J8S10_002973"
     CDS             complement(3746..3988)
                     /locus_tag="J8S10_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAZ9631502.1"
                     /translation="MKQNKRYIPFIPLTTIKAAASGDSIAMSIVLSKYQNYISRLAMK
                     PVYEEEKGMVMYVDEYMRRQLETKLIEKILEFDTTR"
     gene            complement(3975..4403)
                     /locus_tag="J8S10_002974"
     CDS             complement(3975..4403)
                     /locus_tag="J8S10_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAZ9631503.1"
                     /translation="MGDSEETHIQHTFDSFCKKVVCNEALNIQKKYARFRQRQISMEI
                     LEQKGLGTEFYYLEPNLNSSGTFIVLGMKIFISNEELANAIAALPSQRQEIIFMSFFI
                     GLNDREIGDIIGKSLGSVWYQRQMALEELGKYLGVKYEAK"
BASE COUNT         1418 a          841 c          663 g         1555 t
ORIGIN      
        1 ataaaaaatc atcaaataat cctttacacg ttattctaaa tttaattttt attattttat
       61 tgatgtatag aaagtttggg gctttttttc tctttttatt ctaaggttat tttagtcttg
      121 tcctttaata caaagatttt atttttaaat aaaaaatact ctttttttac gattattgaa
      181 aaaaaaagat aaaacttgat taattgaagt attgcttaaa tttggaagct atgagggaag
      241 aataaaagag ttaggacggg attatctact atttttcttt gttttaaata tttgttatct
      301 ttgaacataa aagagaaatg tgtcgactgc agtgttgtgt ccctcatcac gaataaacgg
      361 tgttcaatta gctgatcttg tattcactta aaaaatggta aagtacgagt tgctattccc
      421 cattttcaat tttctaacgc tcaggacaaa atactgtttt cacaacctca ttggaataaa
      481 agcatatata ttgtttcaag aacgaaatct tgttatcttt ttaaagggca tctgtccaaa
      541 atctaatttt aggaggtacg ttttggtatt tattcgtaca aataaaagag aattatcttt
      601 attcatgtaa cgcatccaat tgattttttc atgtacgctc ctggaacgat tttactgacg
      661 attgcttatt taactgcgaa tcgctcatta gcttttatca tagctatcca tattttgaat
      721 aacgttcttg gctttgtatt atagatacag atgacaaaaa aagttcaagt atgcggtgta
      781 gaaccaatat cgcatacttg aacttttttc aatgagtata aattaaaact tctaattttc
      841 aattcccatc atctgatatg cccgaccgtc tgaacttctt ttgaaaaagc caaatgtgat
      901 tagataacgt ctttgttcga cataatcgcc actagaaaat acgttcagca gtatcgaatt
      961 aacctctgtt tctgtataag tcactccatg gtcaaagcgt ttcaagactt ctttcaatag
     1021 gatgtatttc ttttttgttg aacttggtac ttgttttact tttccatcat tcatgaatgt
     1081 gtctaaaact ttcatctttt cttgctccgt ataagtataa accatcttct ttctcctttt
     1141 gattctaaga atactccatt tatgttagaa tattctggat tttttattaa agcggttact
     1201 cttaagaaag atattatcat agtgctcttt tttttactac tacttatagg tagatttatt
     1261 ctaatccatt attctcccct accaataatt aaagaaaaaa ctggatcagg gtgttcaaat
     1321 tacatgctaa gaaaaaagaa cccttgaata ccaagggttc tttctcagtc tgataacaat
     1381 gattaacgac ggatttcttt gatacttgtg aaaagtcgtt aaagtattga tataaaagga
     1441 tttttattac ctctgactac atattgacta atttgttaaa aaatcgtttt tcaagaatcc
     1501 tgtaatacca gtgctttcac cgttttttta actctctaaa gaactaaaag caatcagagg
     1561 ttttaccttt tcatttgacg ttaagtggcg ataaattttc gaagttgttt ggtcagtatg
     1621 gcctaagcga tctttcaaga cttcccagct acagtgttcc gctactaagc ttgccattgt
     1681 atgacgagct aaatgagtat gaaatggctt attaattcct gagcgattca cgcaccgttt
     1741 gacgtgatca tttacatact ctcgacgata aggaacacca cgtttactag aatcaagata
     1801 cacaaacaaa tatgtttctt ctataataaa cctgtaatgt tgcctcatct cacccaaagc
     1861 cttaatcaac tgttgtagct tttccataac tagaggagtt actagaactc gtctagcaga
     1921 actaactgtc ttagtagttt caattcgaaa atccttactc ttacctttaa ctgccgtttg
     1981 cttatagaac agaatttcat ttcttttgaa atctatatct ccaggctgta gagcaagcgc
     2041 ctcgctgact cggcagccag tgtaaaatag aacatggaaa agtacagaca tcggtaattc
     2101 ctcatgaaca atgccataat tcaaaaaagt tctcaattca tcgacagtaa gaaacttgtc
     2161 ctcaatatta tttatggctt cttttaaatc agttaccgtt aactgatatt ttggcattct
     2221 cacagacttc attggatttt cacttatcaa attctttctt tgacaatatt taaaaatcat
     2281 atttagaact tgaataagtg attgtaaact atttttggca tagccaacat ttgttccatt
     2341 aacgccacat tcctttaagg taaaaagcaa ttcttgaagg cactctggtg tcaaatcaga
     2401 caacttttta tcaccaatcc atcgaacaat aatttttaat tgttcctctc gcttatcata
     2461 ggttatttcc ttttgttcat ttaacgaacg gtaatattgg aaccattgct cacctacaac
     2521 actaaacttg tcattgcttg caacaatttt tttcttaagc ctttgttgtt tctccatttc
     2581 cagataagcg agttgcgcct cacgttttga attaaagcca cgtcttgttg ttcgatatgc
     2641 ttgaaagtac catgtgatcc taccagtaga actgatttgc ttcttgaatc gatctgtttt
     2701 ttccatttat tgattcctcc tattttgaag gaacccaaca agcagaaacc ctttggaaat
     2761 ctttctatct atgtcatcat tgtaccgcat cttagaaaga aaatgtaact tataaagatc
     2821 gaagtagtcg caatttttct cgatagtcat tcgaatcact ctttctcatc cattctaaaa
     2881 catcatcacg aaaatagtgt cctcgaatcc cgtaccaaca gggaggaaac tcaccaagtt
     2941 ttactaaacg gttcagtgta ctatcactta tctgaaatag tcgctttaaa tcagtatttg
     3001 ttaataccag aggtaaatga ctgactgcaa gcaatttttc cgtgtaatct tccagttttt
     3061 tttgtaaaat tgaatagaac tctatttcca gagaattaac atttgtttta acttccaact
     3121 ccatcaccct tctctctcaa aatcaaaacg accaccacgg taccccttaa aattgtaaaa
     3181 aaacactcca gtactccatc aaaacggact agaaaagagg aatttttaat atgaaacaag
     3241 gaattgcaga cataaaaata attaaagaaa ttcttgaaaa atctacggct aatgcaatag
     3301 cattcggaac aggaatcaac ttgagtacag taaaaaaact taaaagtgga gagagagctg
     3361 aagaaaaatt aaatcttgcc gatgctatta aaatcacaga atttggcatg aaaaatatgc
     3421 caaccaaaat cgaaatatgg aaatagtagt ttttctgatc tatcagctgt tttgccaaag
     3481 cacataggaa tctcacctcc ccccagtaat ggcgggccga tttggttacg gaagtatcat
     3541 tatcgtagtc gcgattctca tattaaaatt tgtcgcttaa aagctaacct tgtcatggcg
     3601 taactagaga atcaaaatct acatgtactg atagatttgc tattcatttg tcaaagagcg
     3661 ctaggctatt ttcagcctat ggaaatcctt tattttgacc cgataaaaaa cttccataga
     3721 atgaaaagga aagggaaaaa atactttaac gagttgtatc aaattcaagt atcttctcaa
     3781 tcaattttgt ttccagttgt ctacgcatat attcatctac atacataacc attccttttt
     3841 cttcttcata aactggtttc atggctaacc gtgaaatata attttgatat tttgacagaa
     3901 cgatggacat ggcaattgaa tcaccagaag ctgcggcttt gattgtcgtt agtggtatga
     3961 atggtatata tcgtttattt tgcttcatat ttgacaccca aatactttcc tagctcttcc
     4021 aaagccattt gtcgttggta ccaaacactg ccgagacttt tcccaataat atcgccaatt
     4081 tcacgatcat taagaccgat gaagaaggac ataaaaatga tttcttgtct ttgactaggt
     4141 aatgctgcaa tcgcatttgc caactcctca ttggaaataa agattttcat accaaggaca
     4201 ataaaagtac cactactatt caaatttggt tccaaataat agaactctgt acctaaccct
     4261 ttttgttcca atatttccat tgatatttgc cgttggcgaa atctagcgta cttcttttga
     4321 atatttaacg cctcattgca gactactttc ttacaaaaac tgtcaaacgt atgttgaatg
     4381 tgggtttcct ctgagtcgcc cataatattc tccccctcaa aaaattcatt caactcgttt
     4441 tacttctatc cctttccatt attactacaa tctagga
//
LOCUS       DADQDV010000143         4459 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.148, whole genome shotgun sequence.
ACCESSION   DADQDV010000143 DADQDV010000000
VERSION     DADQDV010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4459
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.148"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..85)
                     /locus_tag="J8S10_002975"
     CDS             complement(<1..85)
                     /locus_tag="J8S10_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAZ9631504.1"
                     /translation="MPRRQRRTYSKEFKQQIVDLYLAGKPCA"
     gene            161..316
                     /locus_tag="J8S10_002976"
                     /pseudo
     CDS             161..316
                     /locus_tag="J8S10_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="(4Fe-4S)-binding protein"
     gene            335..1612
                     /locus_tag="J8S10_002977"
     CDS             335..1612
                     /locus_tag="J8S10_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9631505.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            1622..2278
                     /locus_tag="J8S10_002978"
     CDS             1622..2278
                     /locus_tag="J8S10_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAZ9631506.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            2278..3654
                     /locus_tag="J8S10_002979"
     CDS             2278..3654
                     /locus_tag="J8S10_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAZ9631507.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGGVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            complement(3940..>4459)
                     /locus_tag="J8S10_002980"
     CDS             complement(3940..>4459)
                     /locus_tag="J8S10_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HAZ9631508.1"
                     /translation="ITRHVWGDLMDEVEHLRLTDLNKSIYKKRKQTIERIFADAKEKH
                     GMRWTKYRGLEKVATHTMLVFAAMNLKKLATWLWKGKEPLFFCSKIRNEVDKKLFQAR
                     VTSLEQLLSTVCDVGDISFSIRNQLRFKRSLPVSGNINVYFTKARFKRLIAITVSSIV
                     MFLWLFRMGVIP"
BASE COUNT         1716 a          537 c          784 g         1422 t
ORIGIN      
        1 ctgcgcaagg cttaccagcg agatagagat cgacgatttg ttgtttgaat tcttttgaat
       61 aggttcttcg ttgacgtctt ggcatgaaaa atcctccagt gtgtttttta ttattctaca
      121 caccttattt tttctgtcta gtctagtgta gccgattcag gataaggata agtgtattaa
      181 ttgtggaaaa tgtaaaaaag tttgccaaat gaataaagat tcagttgaga attgcaatca
      241 tctggagtgt atcagatgtg gacgatgtaa aaatgcttgt ccagtggatg caattagtta
      301 tggagtaaga aaatagaaag gagtagttag gaaagtgata aaaaatgcta tagcatatat
      361 tacaagaaag aaaaatagaa ctttaataat ttttatcata ttaactatag ttctttcttg
      421 cttgtattct tgtttaacaa taatgaaatc aagcaatgaa atagaaaagg ctttatatga
      481 aagttctaat tcttcaatat caataacaaa aaaagatggt aaatatttta atgttaatca
      541 atttaaagat attgaaaaat taaaagaaat tgaagaaaaa ataattcaat atgatggatt
      601 agcaaaacta aaagatgcta aagtagttag cggagaacaa agaataaata gagaagattt
      661 atctgacgaa tttaagaatg ttgtttcact cgaagctaca aataatacta aaagaaatat
      721 tttatttagt agtggagtat ttacaattaa agaaggtaaa aatatagaag aaaatgataa
      781 gaattcaatt attgttcatg aagaatttgc taaacaaaac aatctaaaat taggtgatga
      841 agttgatctt gaattactag atattgaaaa aagtggaaaa ataaaaagtc ataaatttaa
      901 aattataggg atcttttctg gtaaaaaaca ggaaacatat acaggattat cttctgattt
      961 tagtgaaaat atggtgtttg tagattattc aacaagccaa gagatattaa acaattcaga
     1021 aaataatgaa attgcaaata aaattttaat gtattctggt agtgcagaat ctacagactt
     1081 agccttaaac aaattgaaag agcttaaaat tgatgagtca aagtattttg ttgaaaaaga
     1141 ttctaatgcg tttgaagagt ctttagagtc agtgagtgga ataaaatata taataaaagt
     1201 aatgacttat tctattatgt tgggtgggat ggttgttctt tcattaatct tgattctatg
     1261 gttaagggaa agaatttatg aaataggtat attcttatct attggaacat ctaagataca
     1321 aattataatg caatttatat tcgagttaat attcatatcg ataccaagta taatatcttc
     1381 cttattttta ggaaatgtat tactaaaagt aattgtagat ggattcatta actcagagga
     1441 ttcaatgatt tccggtggaa gtttaataaa taatagtagt tttatgtcaa atataacaac
     1501 acttggacaa agttatttaa tattaataag tattattgtt ttatcagttg tatttgcttc
     1561 ttcattaatg ttaatcaaga agcctaaaga aatcttatca aaaataagtt aggagaaaat
     1621 aatggatata ttagaaataa agaatgtagc atatagttat gcaaattcta aagaaaaagt
     1681 tttgtcagga gtaaatcaaa aatttgaact tgggaagttt tatgcgatag taggaaagtc
     1741 aggaacagga aaatctacac ttctttcctt acttgctgga cttgataaac ctcaaacagg
     1801 aaaaatattg tttaagaatg aagatataca aaataaagga tatagtaatc atagaaaaaa
     1861 taatatatct ttagtatttc aaaactataa tttaatagat tatttatcac caattgaaaa
     1921 tattagatta gtaaataaat cagcagatga aagtatcttg tttgaactag gtttagataa
     1981 aaaacaaata aaaagaaatg ttatgaaatt atctggtgga cagcaacaaa gagtagctat
     2041 tgctagagca ttggtatcag atgctccaat aatactagct gatgagccta ctggtaatct
     2101 agacagtgtt actgctggag aaataattaa tatattaaag acattagcta aagatagaaa
     2161 taaatgtgta atagttgtaa cacatagtaa ggaagtagca gattctgcgg atatcatttt
     2221 agaactaagt ggtaaaaagt tgaaaaaagt aaataaaatg aatttggagg ttgaataatg
     2281 ataaaaaatg catttgctta tgtaactaga aaaagtttaa aatcattaat tatcatatta
     2341 gttattttat ctatgtcaac tttaagtctc attagtttat ctattaaaga tgctacggac
     2401 agagcttcaa aagaaacatt tgctaatata acaaatagtt tttctatgga gataaataga
     2461 caagtaaatc caggaacacc tagaggtggg ggaaatgtaa aaggtgaaga tattaaaaag
     2521 atatctcaaa cagatagtat agactcctat gtaaaaagaa taaacagtgt tgcagattta
     2581 gttgattatg atattattga aactcaagag actcttgcga atcaatcacc tgaaagagca
     2641 aagaatttta aaagaacagt tatgttaact ggggttaacg actcaacaaa agaaacaaaa
     2701 tttgtatcag aagcatataa attagtagaa ggaaagcatt tagaaaatga agataaaaat
     2761 aaaatcttaa tgcataaaga tttagctgaa aaaaataacc ttaaagttgg agataagata
     2821 aaaataaaat ctaatttatt tgatgctgat aatgagaaag gtgcagatga aacagtagaa
     2881 gtagaaatta aaggtctatt cgatgggcat aatagcggtg gagtaagtgc agcacaagaa
     2941 ctatacgaaa atacattaat cactgatatt catacagctg ctaaagttta tggtaatacc
     3001 gaagatacag ctgtatacca agatgcaaca ttctttgtaa aaggtgataa gaatcttgat
     3061 agtgtaataa aagatcttgg gaaattagat ataaattgga gagaatataa tttgattaaa
     3121 agttcatcaa attaccctgc attacaacaa tctatatcag gtatttactc aatttcaaat
     3181 aaattatttt ttggctcatt aatatttgca ggagttgtag tttcattatt attattctta
     3241 tggatgaatg ctagaaagaa agaaatagca gtattactat cattaggtat atcaaaatta
     3301 gaaatttttg gtcaattcct aattgagatg gtatttatat caatccccgc attcgttggt
     3361 tcctatttct tagctcaata tacagctgac aagcttggga ataatatatt gaataaggtt
     3421 actggtgata tagctaaaca aatagctaaa caatctgcat ctagccaatt aggtggtggg
     3481 gcagaagctg aaggatttaa caagacatta tcaagtttag atatcaatgt attacctaaa
     3541 ttcatgattt atgtagttat atttatgagt ttagtacttc ttgtatcatt gattatttct
     3601 tcattcaata tattaagaag gaatccaaaa gaattattaa ttgacaataa ttaaaatttt
     3661 cggtgctttt tagcaccaaa aatgagagtg taatataaac cgtgtaagta accatcaatc
     3721 ctaggcgggt ggttgcttca cggtttttat ttttctaaaa taagatcaag aggtgattac
     3781 acgatggcta gaaagaaaag aaatcctgat gctgagaagt tagctgaatc cattttgaat
     3841 acttatcaac ccgaatctgt agaggatatg caagatgttt taaaagatgt gtttggtccc
     3901 ttatttgaaa aaatgcttca aggagaattg aataaccatt tagggtatga cgcccattct
     3961 aaagagccaa agaaacatga caatcgacga aacggttatg gcaataagac gcttaaaacg
     4021 agctttggta aagtaaacat tgatgttccc agagaccggg aggcttcttt tgaacctgag
     4081 ttgattccta atagaaaacg agatgtctcc gacatcgcag actgtagaca aaagctgttc
     4141 caaactcgta actcgagctt ggaacagctt tttatctact tcgtttcgaa tttttgaaca
     4201 aaaaaataaa ggctccttgc ctttccatag ccaggtggct aatttcttta aattcattgc
     4261 agcaaacact agcatcgtat gcgtcgcgac tttttccaag cctcgatact tggtccaacg
     4321 catcccatgc ttttcttttg catccgcaaa tattcgttca atcgtttgtt tccgtttttt
     4381 gtaaattgat ttattcagat ctgttaggcg aagatgttcc acttcatcca tcagatctcc
     4441 ccaaacatgt ctcgtgatg
//
LOCUS       DADQDV010000144         4433 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.149, whole genome shotgun sequence.
ACCESSION   DADQDV010000144 DADQDV010000000
VERSION     DADQDV010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4433
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.149"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(543..2048)
                     /locus_tag="J8S10_002981"
     CDS             complement(543..2048)
                     /locus_tag="J8S10_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAZ9631509.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(2045..2731)
                     /locus_tag="J8S10_002982"
     CDS             complement(2045..2731)
                     /locus_tag="J8S10_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAZ9631510.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="J8S10_002983"
     CDS             complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="J8S10_002983"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HAZ9631511.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
BASE COUNT         1239 a          919 c          729 g         1546 t
ORIGIN      
        1 tctttttgtt ttaacaactc tttaatctta tcagattcag aagagaatgt caacaacttc
       61 tttgtttatt ttttctaaac gtctttgcca ctcattagca gcgacttgat tatcatacca
      121 tctttattgt tatttgtcaa taactttttc gaagtttttt tcgataaaat caagctttat
      181 tagctatctc atccaaacga cttcgttatt ataacatgac atcaaaagtg cgtcaacact
      241 attttttata atttttagtg acaccttaaa ggaatcattt agaacaaata ataatatagc
      301 aatctcttta taaaattgca atagaaaatt ccctattttt atttattatt tttaaacacg
      361 aatattacag cattttattg ttttttcgtt catctaaaag atacttacat ttaattaacg
      421 gatgttattc tatttaattg ttcgctagtt tttttataat gacatccctg aatttctcac
      481 ttgcttgtat tttgtacctt attctttgtt ggatatataa aaaaacaagt aaagcacatg
      541 ctttacttgt cttctgcctt tgcgatagga ataaagattc taaaaattgt cccttgccct
      601 actacacttt ctgctaagat acgtccttta tagttttcaa ccagttgttt agcgatagac
      661 aaccccagac catttccacc cttcgttcta gctcttgctt tatccactcg ataaaaacga
      721 ttgaagatct tattaaggtc ttctttgggt attccttcgc caaagtcctg aatcgcgatc
      781 tcaaattcat tcagagtgga agaaatagag atatggactt cttttcgtgt agttgaatac
      841 tttactgcgt tatccaatat gataatgatt aattgttcaa agtgattacg ataaatttgc
      901 agggtcactt cttttgtcaa atcatcatct aaagtgatca catagtctgg atataatatc
      961 ttgaaattat tataaacttg ataggtgact tcttttcctt tagttgtttc attcgcataa
     1021 tgaacatcta cttgttctgc tcttgataag tctagcatct cttgaactaa gcttttcata
     1081 cggctgattt cttgcatgct ggcgcttaat gattcttcta atatctcagg atcatctttc
     1141 ccccaacgat ttagcagact aagatgccct tcaataattg caacaggtgt ccttaactca
     1201 tgagatacgt cttccacgaa ttgctcttgt tgttcaatat acaaacgcat acggtcaagc
     1261 atctcattga atatttcagc taaatctgcc aattcatcat ttgtgtcgat ttcaggcatg
     1321 tggatatctg attgcggatc tttacgtata gtatccattg tatctctgag taccttgagt
     1381 ggttttaaga aataagaaga taaaaagaaa cctaaaatac tacttaagat caaagaaaca
     1441 acttctaaaa caataagagt caataatagc ttatttcgaa tatcatagaa agaagataat
     1501 tcatagaagc tttgcgcata gccgatcttt tctcttgtac ctttagaata tataggctgg
     1561 atagataaaa agccagtttt tccttctagt gtaacgatcg ttggaacttt acgtgtagtc
     1621 tgaatcaggt ttcgactgtt ttcatgggtt ttaaaaatca agttctcgtc caaatcataa
     1681 acataaagat ccattgatgg ctgccctagc tcagctataa aggaatcgat cttcattaag
     1741 tttccttcga ccagtgaagt atgatctacg acctcatctc cgtcatttgt cgctttcgtc
     1801 agattacgat acgtatttac taatgtcagt tcttcatccg agttagccaa acgagaagct
     1861 acttctgaaa tcgtacgctc tacattgttt ctttcttttg ccacaatcag attgatagat
     1921 gatttatagg taatgacagc gaaaattgta aacacaacga atatgaagaa agaactcgca
     1981 aaggcccact tgattgtcaa ggagggccct ttcagttctc ttttttccga ttttttcggc
     2041 tttatcacga gcgcatcaca taacctgttc cgcgtacagt ttggatatag ctttcctccc
     2101 cgggaacgtc aattttgttg cgaagataac gaatatatac gtccactacg tttgtttcaa
     2161 cttctgtttc gtatccccac actttattta gtaaaacgtc acgtgctaat accacgttca
     2221 cgttttccat taaagtaagc agcaactcgt attctctttt tgttagttca attacttcat
     2281 ttccgcgacg tacgacacgg ttttcttttt cgatagtcaa atcgcgataa gtaatagtag
     2341 tttgtttagc cacattttta tcgccttcaa tatcgattcg acgcaacaat gcacgaagac
     2401 gtgctaataa ttcttcgata gcaaatggtt tgacgatgta gtcatctgct ccgtggtcaa
     2461 gtccagatac acgatcgatc acagaatctc ttgcagtcat cataatgatt ggtgtatttt
     2521 tgacttggcg tacacgtctg cagacttcta aaccgttcaa ttctgggagc atcagatcca
     2581 acaatatggc atcccactca ttatttaatg ccgcatctaa accagttcgg ccgttgtagt
     2641 ggacttctgc gttataccct tcatgcttca actctagctc gacaaatcgt gccaagttct
     2701 tttcatcttc aatgattaga atattgctca tttattattt tatcctttct attctactgg
     2761 ctttttaaaa actctatcat tataccgata atatgcttaa aaatctatag tcattttatc
     2821 atggatagca attttaaaaa agagctgaag tctactcata acaatcgact tcagctcttt
     2881 cgtcctcttt ttattttctc atttcctaac agccgaaaga ctattattct tcatggtacc
     2941 atgagtaatg gaagattcct tctttgtcga cacgctcata ggtatgtgcg ccaaagtaat
     3001 cgcgttgggc ttggattata tttgcaggca gacgttctgc tctgtatgaa tcgaagtaag
     3061 cgatggctga tgagaaagtc ggtacaggta cgccagcttg gacagccaag gcaacgacgt
     3121 ctctgactga ttgctgatat tttttcgtga tttcaacgaa gtaatcatct agcaataaat
     3181 tttcgatctc aggatttttg tcataggcat ccgtaatttt ttgcaagaat cgagctcgga
     3241 tgatacatcc agcgcgccag atttttgcga tttcaccaaa tggcaagtcc caatcaaatt
     3301 cttttgaagc gacacgtaat tgagcaaatc cttgggcata actcatgatt ttactgaaat
     3361 acaacgcttc tcggattttt tcgaccaatt cttttttgtc tcccgtgaac tcaaaatcgt
     3421 tcgtacgaga caaaatcttg cttgcttgta cgcgttcttc tttataagca gaaatatagc
     3481 gggcaaatac agattcagtg atcaatggaa gtggcacacc taagtcaagc gcgctttggc
     3541 ttgtccattt acctgttcct ttattcccag ctgcatcaag gatcacatct actactggtt
     3601 tacctgttcc ttcatcgtct ttacgtgtca gaatgtcagc agtgatttct atcaaatagc
     3661 tgtctaattc gccttgattc cattctttaa agatatcagc catttcttct actgaaaggt
     3721 ttaaaatatt cttcattaag tcataagatt cagcaatcag ttgcatatct ccatactcaa
     3781 taccgttgtg taccattttc acataatgtc cggctccatt tgggccaata tatgtgacac
     3841 atggtgctcc gtcttctgct tttgcagaaa tttgctctaa gattggtgca actagcgcat
     3901 aggcttcttt ttgtccacca ggcatgattg aaggtccttt taaagctcct tcttcaccac
     3961 cggaaacgcc tgtaccgata aagttgatgc cagagttggc taactcttca ttacgacgca
     4021 tcgtatcttt aaagaatgta tttcctccgt caatcaaaat atcgccttta tcaaggtgag
     4081 gaagtaactc ttggattgtt gcatctgttg ccggtcctgc tttgaccatt agcaagatcc
     4141 gacgtggttt ctcgatagat tctacaaatt cttcgattgt atatgttgct ttgaaatttt
     4201 tatctgggtg ttcttctact acagcggttg ttttagcccc tgtacgattg aataaagcca
     4261 ctgaatagcc gcggctttct atgttcaagg ctagattttt acccataacg gccataccga
     4321 caacgccgat ttgttgtttt gacatatgaa ctcctcctac atacgggatt tctccctaat
     4381 ctcttacatt atagcttaac acggctacat tgcaaactaa agaacaacat att
//
LOCUS       DADQDV010000145         4378 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.150, whole genome shotgun sequence.
ACCESSION   DADQDV010000145 DADQDV010000000
VERSION     DADQDV010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4378)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4378)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4378
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.150"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..650)
                     /locus_tag="J8S10_002984"
     CDS             complement(<1..650)
                     /locus_tag="J8S10_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAZ9631512.1"
                     /translation="MKGDVIVEIKVLFENSRINLNFKSGHGLSLLINYSGKKYLFDAG
                     ANKKLVYNATKMGETLNDLEAVIISHGHSDHTGGLRYLKSGNAPIYTAEGVTLPHYLK
                     ILTTFLYVGIPKNEILKMHENLHTIKTKTELAPSFHIIPLGKANSTTKNLYKKMDDKF
                     VYDDFSDELLVVIEQEDGLIVFTGCSHHGIIDMMEIALETFPTKPIKYLIGGFHMIG"
     gene            975..1391
                     /locus_tag="J8S10_002985"
     CDS             975..1391
                     /locus_tag="J8S10_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAZ9631513.1"
                     /translation="MATIILASHGEFAQGLKQTATMIIGDSVPIHALSAFRDEDESIL
                     VQIKKLLATIDIEETYILTDILGGSVNNDMLTIIKEYEGLQLITGMNLPLVISIATYN
                     GKIGESELEKLIKESQQSVIDCRKLLVEQLTGGDDL"
     gene            1388..1858
                     /locus_tag="J8S10_002986"
     CDS             1388..1858
                     /locus_tag="J8S10_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAZ9631514.1"
                     /translation="MIKLVRIDHRLLHGQVVFSWSKSLNINRIIIANKEAANDEFKKM
                     SLNLSKPTGIKLTIFSVEQLLEKMPKIETLNENIMLIFGNTKEIRQFCEAYPKVQEIN
                     YGGIIKKEGSKQFSNAIFLNESEQEDAKKLKALGIKQFIQQVPTSKKEDLNTML"
     gene            1872..2645
                     /locus_tag="J8S10_002987"
     CDS             1872..2645
                     /locus_tag="J8S10_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAZ9631515.1"
                     /translation="MLVQSIGLGLIGVFCILDSRLLGRMNFERPLIVSTLVGLVLGDM
                     EKGLIVGASLELMSLGLVNIGAAAPPDMNMASIIATAFAILSNANAEAALTIAIPISV
                     LGQILGILMRTILSNLTHVADRFIEQGKFSQARRIHILYGSGLYALMYFIPIFLAIYF
                     GTNLVSQIVDAIPEWLTNGLTVASKILPAYGFALLLQTMLTKKMVPFLLLGFLITAYS
                     GLGIIGIAAFACIVAFVMVQVQGKNSNGNQNEPDPLDDL"
     gene            2659..3471
                     /locus_tag="J8S10_002988"
     CDS             2659..3471
                     /locus_tag="J8S10_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAZ9631516.1"
                     /translation="MKEKDQNAWKYRQFLWRSWAIQASWNYERQMNMGFMYGIAPILD
                     NIYKNPEDEAMKKEAYERHMMYYNCTPQTSAFVLGLTASMEEQYYEDQENFNPESISA
                     VKTSLMGPLSGVGDSFFQGTIRVLAFGLGINLAQQGSILGPILAMLISFVPSFLVTYY
                     GGKIGYNMGNKYLSKLYQEGLMDKVMYVCSIVGLMVIGSMIASMIGITTPIQMGKAFV
                     LQDVLDSIMPQFLPLGLTFFMYWLLQKKVKTGWMLAICLVGGIIFSLLGILQ"
     gene            3525..>4378
                     /locus_tag="J8S10_002989"
     CDS             3525..>4378
                     /locus_tag="J8S10_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAZ9631517.1"
                     /translation="MNSKEIVKEIVAKKEVKSIVFVGCGASKADLYPAKYFLDQNAKQ
                     LRISHYTASEFNYATPASVDESTVVISASLGGTTPETVEANAVAKEKGATVISLTRSI
                     DSPLTKDADYVIYHRFAENYAAKLEKTGYCLELAVELLHQVEGYDHYEAMQEGFATIY
                     DLAQKSAESARKDAKKFAERFKDEKVIYVMSSGATHEVAYSTSICLMMEMQWINSGTF
                     HSGEFFHGPFEIVDKDVPFILLMNDGKTRNIDARALTFLERFDTKTEVVDALDYGLSS
                     HIAKEVLD"
BASE COUNT         1455 a          673 c          864 g         1386 t
ORIGIN      
        1 ccaatcatat ggaagccacc gattaggtat tttatgggtt tagtcggaaa tgtttcaaga
       61 gcaatttcca tcatatcgat aatgccatga tgactacagc cagtaaagac aatcagaccg
      121 tcttcttgct caattacgac caataattca tctgaaaaat catcataaac aaatttatca
      181 tccatctttt tgtataaatt cttggtggtc gagtttgctt tgcctagggg gatgatatgg
      241 aagctcggag caagttctgt tttcgttttt attgtatgta aattctcatg cattttaagg
      301 atttcatttt taggaatacc aacatacaga aacgtggtta aaatctttaa ataatggggt
      361 aaagttacac cttcagctgt ataaataggg gcgtttcctg attttaaata tcttaacccg
      421 ccggtgtggt cagaatgacc gtgtgaaata atcactgcct ccagatcatt caaagtttcc
      481 cccattttag tcgcattata gactaatttt ttattagcgc cagcatcgaa gagatatttc
      541 ttccctgagt agttaattaa gagagataac ccatgtccac ttttaaagtt caaatttatt
      601 cttgagtttt caaataaaac cttgatttcc actataacat ctcctttcac atgaacgtgt
      661 attcatatat tgtagcacat taagttctat tttttgttgt aattaccgaa aaaaatatta
      721 atggacgctt tttacgcttt atttcgtatg tggaagaaaa tttcttagga tgtggcgggg
      781 gattggggca aagctaaatt ccaattacag tgatcattta attagacacc tttaaatacc
      841 cacactttca tcaacactat aatttaggga aagaaaagtg ttggcatgat atagaaaaac
      901 ctttaattaa cagcgtttcc taaaattggc acgcatcttg cttatagaaa agcgtaagga
      961 taggaggaat gaaaatggca actataattc ttgccagcca tggggaattt gctcaaggat
     1021 taaagcaaac agctacaatg attattggag atagtgtacc aattcatgcc ttgtcagcat
     1081 ttagagatga agatgaatct attttggtac aaataaaaaa acttttagcc acaatagata
     1141 tagaagaaac ctacatttta actgatattc taggtggtag tgtgaataat gatatgctca
     1201 ctattattaa agagtatgag ggattgcaat taattactgg aatgaactta cctttagtta
     1261 tttctattgc aacctataat ggaaaaattg gggaaagtga gctagaaaag cttattaaag
     1321 agagtcaaca atcagtgatt gattgtagaa aattattagt agaacaactt actggaggag
     1381 atgacctatg attaagttag tacgtattga ccatcgtttg ttgcacggac aggtagtatt
     1441 ttcttggagt aaatcattaa atatcaatcg tattattatt gccaataaag aggcagcgaa
     1501 tgatgaattc aaaaaaatgt ctttgaattt atctaaaccg actggcatta aattaacaat
     1561 tttttcagtt gaacagttac tagaaaaaat gcctaaaatc gaaacactta acgaaaatat
     1621 catgcttatt tttggtaata caaaagaaat tcgtcaattt tgtgaagcct atcctaaagt
     1681 acaagaaatc aactatggag ggataatcaa aaaagaaggt tccaagcaat ttagtaatgc
     1741 cattttcttg aatgaatctg agcaagaaga tgccaaaaaa ttaaaagctc ttggcattaa
     1801 acaatttatt caacaggtac caacttctaa aaaagaagat ttgaatacaa tgttataaag
     1861 gaggaatgaa aatgctcgtt cagtcaattg gtttagggtt aatcggtgtt ttttgtattt
     1921 tagactcaag gcttttagga agaatgaatt ttgaacgacc gttgattgtc agtacgcttg
     1981 ttggtttggt acttggagac atggaaaaag gattaattgt tggagcctct ttggaattga
     2041 tgtccttagg attagtaaat atcggagctg ctgcaccacc tgatatgaat atggcatcaa
     2101 ttattgctac agcctttgcc attttatcaa atgcgaatgc agaagcagca ttaacgattg
     2161 ccattccaat ttcagtgtta ggtcaaatac taggtatctt aatgcggacg attttgtcaa
     2221 atttgactca cgttgcggat cgctttatcg aacaagggaa atttagccaa gcaaggagaa
     2281 ttcatatact ttatggctcg ggattatatg ctctcatgta ttttattcct atttttctag
     2341 caatttattt tggaacgaat cttgtttctc agattgttga tgcgattcct gagtggctaa
     2401 caaatggctt aacggttgca agtaaaattt taccagcata tgggtttgcg ttgttattac
     2461 aaacgatgtt aacgaaaaaa atggtgccat ttttattact tggattttta attactgctt
     2521 attctggatt gggaatcatt ggtattgcag ccttcgcatg tattgttgcg tttgtcatgg
     2581 ttcaagttca aggtaaaaac tcaaatggta accaaaatga gccagatcca ttagatgact
     2641 tataaggagg tagattaagt gaaagagaaa gatcaaaatg catggaaata tcggcagttc
     2701 ttatggcgtt catgggcaat tcaagcctca tggaactatg aacgacaaat gaacatgggt
     2761 tttatgtacg gaattgcacc aattctagat aacatttaca agaatccaga agatgaagca
     2821 atgaagaaag aagcttacga gcggcatatg atgtactaca actgtacccc tcaaacaagt
     2881 gcatttgtgt tagggttaac tgcttctatg gaggagcaat actacgaaga ccaagaaaac
     2941 tttaatccgg aatcaatcag tgcagtgaag acttctctga tgggaccgct atctggtgtt
     3001 ggtgattctt tctttcaagg aacgattcgg gtattagcct ttggactagg aattaattta
     3061 gcccaacaag gtagtatttt aggtccaatt ctagcaatgt taatttcctt tgtaccttcc
     3121 tttttagtta cttactatgg tgggaaaatt ggctataaca tggggaataa atacttgtct
     3181 aaactgtatc aagaaggttt gatggataaa gtaatgtatg tttgctccat tgtggggttg
     3241 atggtcattg gttcgatgat tgccagcatg atcgggatta caacaccaat tcaaatgggt
     3301 aaagcttttg tcttacaaga tgtattagat agtattatgc cacaattttt accattagga
     3361 ttaaccttct tcatgtactg gttattgcag aaaaaggtca aaacaggatg gatgttggca
     3421 atctgtttag tcggaggaat tatttttagt ttgttaggta tcttacaata agggaataac
     3481 caataaattt ggttgaataa tataaataag gaggaattca attgatgaat tcaaaagaaa
     3541 ttgttaaaga aatcgtagcg aaaaaagagg taaaatcaat cgtatttgtt ggctgtggcg
     3601 cttcaaaagc ggacctttat cctgcaaagt attttctaga ccaaaatgcg aagcagttac
     3661 ggattagtca ttacacagcc agcgaattta actatgcaac accagcatct gtagatgagt
     3721 caactgtcgt tatttcagct tctttaggag gtacgactcc agaaacagtt gaagctaacg
     3781 cagtagctaa agaaaaaggt gctacagtta ttagtctaac acgaagcatt gactcaccgt
     3841 taacaaaaga tgcagattat gtaatttatc atcgatttgc agagaactat gctgctaaat
     3901 tagaaaaaac aggctactgt ttagaattgg cagtagaact tttacatcaa gtagaaggtt
     3961 atgaccatta tgaagcaatg caagaaggat ttgctactat ctatgatctt gcccaaaaaa
     4021 gtgcagaatc agctcgtaaa gatgcgaaga aatttgctga acgctttaaa gatgaaaaag
     4081 ttatttatgt aatgagtagt ggtgctacac atgaagtagc atactcaaca tcaatttgct
     4141 tgatgatgga aatgcaatgg attaattctg gtaccttcca ttcaggagaa tttttccacg
     4201 gaccattcga aattgtggat aaagacgtac cgtttatatt attaatgaat gatggaaaaa
     4261 ctagaaatat agatgctcga gcattaactt tccttgaacg ctttgatacg aaaacagaag
     4321 ttgtagatgc cttggattat ggcttgtctt cacatattgc taaagaagtc ttagacta
//
LOCUS       DADQDV010000146         4215 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.151, whole genome shotgun sequence.
ACCESSION   DADQDV010000146 DADQDV010000000
VERSION     DADQDV010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4215)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4215)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4215
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.151"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..2955)
                     /locus_tag="J8S10_002990"
     CDS             complement(<1..2955)
                     /locus_tag="J8S10_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016249808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631518.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTGLTTGEDGKLAIDGLAPGAYQLVETQAPIGYELDATPIEFEIERSQTAVVELTKE
                     NRLTPGGVVLTKIDDQSGEILQGAVFELQNREGETLQTGLTTGEDGKLAIDGLAPGTY
                     QLVETQAPIGYELDATPIEFEIERSQTAVVELTKANRLTPGGVVLTKIDDQSGEILQG
                     AVFELQNREGETLQTGLTTGEDGKLAIDGLAPGAYQLVETQAPIGYELDATPIEFEIE
                     RSQTAVVELTKEN"
     gene            complement(3627..3895)
                     /locus_tag="J8S10_002991"
                     /pseudo
     CDS             complement(3627..3895)
                     /locus_tag="J8S10_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
BASE COUNT         1117 a          971 c          682 g         1445 t
ORIGIN      
        1 gttttctttc gttaattcta ccaccgctgt ctgacttctt tcgatctcaa actcgattgg
       61 tgtcgcatct aattcatacc ctattggcgc ttgagtttct accagctgat atgctcctgg
      121 tgctaaaccg tcaattgcca gttttccatc ttctcctgta gttagaccgg tttgtagcgt
      181 ttctccttct cggttctgta actcaaaaac agctccttgc aggatttccc cgctttggtc
      241 atcgatcttt gtcaacacga caccgcctgg tgtaagtcgg tttgctttcg tcaattctac
      301 caccgctgtc tgacttcttt cgatctcaaa ctcgattggt gtcgcatcta attcataccc
      361 tattggcgct tgggtttcta ccagctgata tgttcctggt gctaaaccgt caattgccag
      421 ttttccatct tctcctgtag ttagaccggt ttgtagcgtt tctccttctc ggttctgtaa
      481 ctcaaaaaca gctccttgca ggatttcccc gctttggtca tcgatctttg tcaacacgac
      541 accgcctggt gtaagtcggt tttctttcgt caattctacc accgctgtct gacttctttc
      601 gatctcaaac tcgattggtg tcgcatctaa ttcataccct attggcgctt gagtttctac
      661 cagctgatat gctcctggtg ctaaaccgtc aattgccagt tttccatctt ctcctgtagt
      721 taaaccggtt tgtagcgttt ctccttctcg gttctgtaac tcaaaaacag ctccttgaag
      781 gacttcacca ctgccttcag catgtttaat tagttcaaca ccacccgtat caaggatgtt
      841 ttcaatggtt aacgtcactt cttctatgga gtattcattt ataaaaacat catgtaccgt
      901 cgcatctaaa agataccctt ccggtgcttc tgtttctcgg acttgatagc tacctacagg
      961 aagcggttca cttaaaaatt ctccgttttc tgccgttata ccttcttgta tcacttgtga
     1021 atcgcttgat aaaatttcaa attttgctcc tgccagcctt tggccattct catcagtttt
     1081 aattacttta atacgcccat cgattttcct tgttcttaca gtactcgtat tcaatcgatt
     1141 gtcactattc acaagcgttg caaagtttaa aatttgatcg ccgaccgcat acgcctctac
     1201 attgacctta aaagagaggg taaaacttgt cggaccacca atcgtattat tcgcactgaa
     1261 acgaactatt ccattattga cttcggcatc aatgaaagag ggaatatctg atagaaatga
     1321 cacaaattcc atgccttctt ccaaaacatc ttcaataaca agcgtatttc ttgttccaga
     1381 aaacatcgag acatgcagag tatacgttag ttcattttca ttgagattga taacattttt
     1441 gtccacactt tttcttaaag agattgccgg aagattactt tcagggattc tcaagcggta
     1501 gtctcggctc attacctgat tattgtaggt catactcgct cgattccgag aaaacccatc
     1561 ctcttgtctt ccttcattga acaagtcgac atcggtcact tcaagagcat attcaataaa
     1621 atacgattga ccctctgcta gattaccaaa gtccacaaca agtgtattcg tttccttatt
     1681 aaaagatact ttgtccacaa attcctcgga aacataatga gttctaacgt ttgcttcacc
     1741 tggattcgtt acttctgcga tccgaacccc acctgaaata ggttctctat ttccagtgga
     1801 actccatgta gtcggattcg gtgccaaagt tgttccttgc ggtagtacat cggtaaccac
     1861 tacaccgtct tttcgtgatc cttcataatt tacctgcaaa ataaatttat tactgttggt
     1921 cacgtcttgc ccgtcaatca gcagattccc aagatttcct tggctgtcga tttctctaga
     1981 gccatagtat aatttcgaaa aaatgggtct tgatgaagga ataggcgtaa ttgaaaattc
     2041 cgtgtttgct gctcgctcag cataagtaag actcacttga aagtcattat ttggctcagt
     2101 accgcctgat tgaaagaaag caacttcaaa cgtgatactg aatgtatacg actgagcggc
     2161 ttcatttaat ccttcataat caaaggtaaa tggaaaaaca acgtctgtgc cttcttggta
     2221 aaatgccagt ggctttaaag gtgaatcatc agcgacctcc actctaatga actcaattaa
     2281 gccaatcgat gctctaggaa ctcgtacgac catctcccca tattcttcaa gaatatcgcc
     2341 agcgcctcct tgaatgtatc cctttaacgt ttgtgtatgc ctgctcggca aagtggggcg
     2401 ctcagcagag atgccgatgt cataattcaa gagctcctct tgtctttcaa tctgagattc
     2461 ctgcgttata gatggctcag atgatctggc ttcattaaaa gattcactta agctttcttc
     2521 tggtatatta aaagattcac ttgtgctttc ttctggtaca ttaaaagact cacttgtgct
     2581 ttcttctggt acactgattt ctattgagac cgtatttgat tgaatatcac cgcttcttgc
     2641 ggtcaattcg tatttacctg aatgctggga agaataagta atcagacgtt cgtaatcatt
     2701 gagttgcttc acttcccctt caatcaaatc ctcactctta tcaatgacca atgcatttag
     2761 caggtctggt gttcctctga ctcgcaactg gaactgctca cccaaagcag cctcctcttg
     2821 atcaacttcg atcgtcagcg aacgctctgg ctgttctgct aaagactcag ctagaaccgt
     2881 tatgttccca aattgattga tcacaataag cataactaga aacatactta acagtttatg
     2941 aaatttgttc ctcactatta ctccccctta taattttgac taaacaacaa ggtacccgat
     3001 aattttctaa aaagattccc caactcaaaa tggctgcgtt acctccctcg tattttcggt
     3061 tcaactcaag cgttgcaatg taagctgtaa acaaagctaa tgattgccga ttgtcttctg
     3121 ttgattgatt cgatagcttt gtatgacttt tagttgtccg tgtggcttaa ccataattat
     3181 gatttcacga ttcctcctgc cagtgccttg cacaagctgg agcgtaaccc taatagttat
     3241 tttgttaatg tacttatata cttttatact tttccattag aaacaatcac taaatcgttg
     3301 ataccaaggt cagactctag aatttcatca gtgagtccct gtattggtta accttcatca
     3361 atcccaaaaa aatatatcaa tgcttagcat caaaatgaat atatagttta gaatacttgg
     3421 gattcatcga taactgatcg cttatttggc catattattt ggcacttggt tcaactaaac
     3481 gcatttagga tgttccttca ttctcgtcat ggatgttctc aaaccgtcat tactaataaa
     3541 ctgtccaccg aatcgatggt tcatttcttg cattttccac gtccaattac tctttttgct
     3601 ctttatttgg gcgtagtttc actttcttaa cttgtatcgt cttccatcaa ctccttaatc
     3661 atcttcttag ctttattggc tcggtttcct tgtaaaaggt atctacaaat agtgacaatc
     3721 tgtattaaat cttcatcatt ttctgtaatg tcaataattt ctatattctg taccatatat
     3781 tgcaaagggt ttcactaagt tcataaccga agcgaattaa acaacttttg tatagaataa
     3841 ctaccttttc tatttttcca ttggtaattc tatctattaa ttggtttaat ccttttgttg
     3901 tagttgattc cactaccaag atgattctct cgaattttaa agcttgaaga tgtattgcta
     3961 tttttgctaa ctggcgtatt tgcaactatt tttcccttct attcttcctt cattgattcc
     4021 cctctaaaat tactatccat aaaaaattgc ataaatgaca atagtattta tattagtcat
     4081 actgcttttt aacacagcaa attccagaaa aacattcgtt acatatttgt gaatttttcc
     4141 aaaaaataac atttttataa aacgacgaaa aataaatcac taccagtcaa cttctataat
     4201 attaccaaat aacaa
//
LOCUS       DADQDV010000147         4179 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.152, whole genome shotgun sequence.
ACCESSION   DADQDV010000147 DADQDV010000000
VERSION     DADQDV010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4179)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4179)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4179
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.152"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(21..287)
                     /locus_tag="J8S10_002992"
     CDS             complement(21..287)
                     /locus_tag="J8S10_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631519.1"
                     /translation="MNILSEEFLTRLRIAIVEVVKDALSQLSKKNLSETRYLKKIEAR
                     KYVGGVNDQGFEKLIAHGLKEIRIDGFLRYDKKDIDELMAKYKI"
     gene            complement(298..489)
                     /locus_tag="J8S10_002993"
     CDS             complement(298..489)
                     /locus_tag="J8S10_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631520.1"
                     /translation="MSNLDNGRAAIKEFMKENGITMDDLATAYGHTRVRMQQILDGHW
                     SGPKANRTILEIIRDYRIR"
     gene            780..1202
                     /locus_tag="J8S10_002994"
     CDS             780..1202
                     /locus_tag="J8S10_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAZ9631521.1"
                     /translation="MTTFERIKELAKNKNKNLQQVAKDLKYGENYFYSLNAGKQPTAE
                     KLQEIADYFDVSVDYLLGRTEKKRYYDLTEKDERDIQKELQSLIDDLSNADGMAFSKK
                     DNEMSEATREALIISLENALRIAKIEAKKKYTPKKYRD"
     gene            1219..1641
                     /locus_tag="J8S10_002995"
     CDS             1219..1641
                     /locus_tag="J8S10_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HAZ9631522.1"
                     /translation="MYLPQIDNKINKLVKLYQTRNPFRIARELKILVLEEDLGEIYGY
                     YSKFKQIKMIHINSSLDEMGKWITCSHELGHCVLHPNENTPMLSKKTLVSELKIEKEA
                     NYFATHLTIDPTLDGFDHMTKYEKLVCFGLPDEFDRFL"
     gene            1670..1870
                     /locus_tag="J8S10_002996"
     CDS             1670..1870
                     /locus_tag="J8S10_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631523.1"
                     /translation="MKIGMRKPSIKKSISARTTGKAKRKVKKAVIPGYGKKGSGWIKD
                     PKKAAYNKVYKKTTFSFWDLFK"
     gene            1957..2845
                     /locus_tag="J8S10_002997"
                     /pseudo
     CDS             1957..2845
                     /locus_tag="J8S10_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317363.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
     gene            2983..>4179
                     /locus_tag="J8S10_002998"
     CDS             2983..>4179
                     /locus_tag="J8S10_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAZ9631524.1"
                     /translation="MAKKEIDKRIKKHLTKKGEEKYQFSLYLGVDPLTGKKRKTTRRG
                     FSTPLAAERALKRLEADIQEKGLQASTAQKSKKFEYVYGLWFENYKKTVKESTWSSTK
                     QIFDTHILKVFGDKFIDKIDVFFCQEAVNTWSDSHPKIFKKIKNYTSNVFDYAASLQI
                     ITSNPMKLVSIPRGEALDIEDKNIEFYTKEELIKFLEAIRNDDDERYLFFSLLAFTGI
                     RKGEAFALTWSDIDFKSKTLNINKTVTRGYQGRLIVNTPKSKSGKRKIYLDNDLISLL
                     RKYYTKNKTIVTIQRENLIFHHDGLLYNPTVSRSWLNVIYKHHPELTKRITTHGFRHT
                     HASLLFESGASLKDVQERLGHADIQTTSNIYTHVTETQNKKVINNFVAFMKNSTQGES
                     KGESKNI"
BASE COUNT         1574 a          705 c          699 g         1201 t
ORIGIN      
        1 ctttcccatg ttgacctcct ttaaattttg tatttagcca tcagttcatc gatgtccttt
       61 ttgtcatatc ttaaaaagcc atctatacga atttctttta aaccgtgagc tattaacttc
      121 tcaaaacctt gatcgtttac acctcccaca tattttctag cttcgatctt ttttaaatat
      181 cgtgtttctg acaaattctt ttttgaaagt tgactaagtg cgtcctttac aacttcaaca
      241 attgcaattc ttaaacgagt caaaaactct tcgcttagaa tattcatgac ttgcctccta
      301 tcgaattctg taatcacgga tgatctctag aatagttctg tttgcctttg gtccactcca
      361 gtgtccatca agaatttgtt gcattcgtac acgcgtgtga ccataagcag tagccaaatc
      421 atccatagtt attccattct ctttcataaa ctctttgatc gccgcacgac cgttatccaa
      481 gtttgacatt aacccacttc ctttttttat aaatttgtaa gttaaaatga tagaaaaaat
      541 ataatttcca ttgacatttt tacactatag agtaaaatga atacatagag aaataagcct
      601 ataacaaaac cttttatttg cacttggtcg ccaaacttta tgctataagg tgtgttttta
      661 gtttgctttt ttctatcaaa ttaacttacg gataaataat aactctatat cgtaaaattg
      721 taaagctatt tttactcttt ttcgtaaatt attttttcgt gttggaaagg aacgttggaa
      781 tgacaacatt tgaaagaata aaagaactag cgaaaaacaa gaataaaaac cttcaacaag
      841 tcgctaaaga tttgaagtac ggagagaatt acttttatag tttaaacgca ggaaaacagc
      901 caactgccga aaagttacaa gaaattgctg actacttcga cgtatctgta gattatttgc
      961 taggacgtac tgagaaaaaa agatactatg atttaacaga aaaagacgag cgtgatatcc
     1021 aaaaagaatt gcagtcatta atcgacgatt tatctaatgc tgatggaatg gctttttcga
     1081 agaaagataa tgaaatgagt gaagcgacac gtgaagctct cattatttct ttagagaatg
     1141 ctttgcgaat agctaaaata gaagctaaga aaaaatacac acctaaaaaa tatcgcgatt
     1201 aaaaggagta cgttgtttat gtatttacct caaattgata acaaaattaa taagctggta
     1261 aaactatatc aaacacgcaa tccttttaga attgcacgag aattgaagat actagtttta
     1321 gaagaagatt tgggagaaat ttatggttac tatagtaaat tcaaacagat aaaaatgatc
     1381 cacataaatt ctagtttaga tgagatggga aaatggataa cttgtagtca tgaattaggc
     1441 cactgtgttt tgcatccgaa tgaaaacaca cctatgttgt ctaaaaaaac gctagtatct
     1501 gaattaaaaa ttgaaaaaga agcaaattat ttcgcaactc atctgactat tgatccaact
     1561 ttagacggct ttgatcatat gacaaaatat gaaaagctcg tctgctttgg attaccagat
     1621 gaattcgatc gtttcttgtg aattataata caacgtaagg aggatataga tgaaaatagg
     1681 aatgagaaaa ccaagtataa aaaaatccat aagcgctaga accactggaa aagcaaaaag
     1741 aaaagtaaaa aaagcagtta ttcctggtta tgggaaaaaa ggtagcggct ggattaaaga
     1801 cccaaaaaag gctgcttaca ataaagtata caagaaaact acattcagtt tttgggattt
     1861 atttaaataa aaaaagcccg tgcagcaaca cggactcgaa accttatttc taagattccc
     1921 caataaaaat catatcatag aaatgaggaa taaaaaatga aaaaagtaat aacaagttta
     1981 ttagtttttg cttctctgtt acttttcact gcttgtggta aaaaagtaac tacagaagat
     2041 ttaaaagcta atgattggtt gattgaagca accaaagatg acgaacctaa tatgatcgta
     2101 tcattttctg atcacgtcgt atcttttagt gttgacacaa gttctatgaa atcaacttca
     2161 agtaacgatt gggaggctat gggagaagaa tttgctaaaa gcttagtcga ccaaatgaat
     2221 tacaaatttg agtatacact tgaaggcgat gttatgactt ggaaagatga taaagacaaa
     2281 gataatgatg ccaaatatac tgtcagcaaa gaagataaaa atattatttt aactccagaa
     2341 aagcctaaca aatctgatga taatgagaaa ttagttttga aaccctacaa aaaggaaaaa
     2401 aactaaagaa tctagaacaa ctactagctc aacaagtagc aacgaacaat catcttcgac
     2461 tacaacagaa agtactattg catcttctag tactgtagaa caagctgcta ttgcgcagaa
     2521 tacgcctcct gaaactagta gtacttactc tgctgaaagt gtagaaaact atgcagaagc
     2581 tactcctagt tcaagtgttg aacaagtttc acccactccc agttcaacgg agcaatcagt
     2641 accacaagat tatgtaccag ctaatcaagc tcaaccaacg gcaccttctt catctgaaac
     2701 cgaaaccttg actttgcaac ctggtgaagg gaccaaacaa atagctgaac gagctggaat
     2761 tacggtagat caactgtttg cattaaacgg tatggatcca aacaactaca tgctttatcc
     2821 aggacaagaa ctaagagtga aataaaaaaa gcacatttgc cgcccgacca agaacgcaaa
     2881 tgtgcaaaga gctacggtaa agtaggtcta tttgttgtac cctattttac catctcgaaa
     2941 tccgctgtac aaccgaacaa acgtacgaaa ggaaagataa agatggcaaa aaaagaaatt
     3001 gataaacgaa ttaaaaagca cttaacaaaa aaaggcgaag aaaaatatca gtttagtctg
     3061 tacttaggag ttgatcctct aacaggaaaa aaaagaaaaa caacgagacg aggttttagt
     3121 acgccattag ccgctgagag agctttaaaa agattggagg cagatataca ggaaaaagga
     3181 ctgcaagctt ctacagctca aaagagcaag aaattcgaat atgtttacgg cttatggttt
     3241 gaaaattata aaaagacagt taaagaaagc acttggtcct ccaccaaaca aatttttgac
     3301 acacacatct taaaagtgtt tggagataag ttcattgaca aaatagacgt ttttttctgt
     3361 caagaagcag taaacacttg gtccgatagc catcctaaaa tttttaagaa aataaaaaat
     3421 tacacatcta atgtttttga ttacgctgct tctttacaaa ttataactag caatcctatg
     3481 aaattagttt ctattccacg tggagaagct ctagatatcg aagataaaaa tatcgaattt
     3541 tatactaaag aagaattaat caaattttta gaagcaataa gaaacgatga tgatgaaaga
     3601 tatttattct tttccctatt ggcttttaca ggtataagaa aaggagaagc ttttgctctg
     3661 acctggtcgg atattgactt taagagcaaa acactcaata tcaataaaac tgtaacaaga
     3721 ggttatcaag gaagattgat cgtaaatact cctaaatcaa aatctggaaa aagaaaaatt
     3781 tatctggaca atgatttgat cagtttattg agaaagtatt atacaaaaaa caaaacgatc
     3841 gttacaatcc aaagggaaaa cttaattttt caccatgatg gtcttctcta taaccctaca
     3901 gtttcacgtt cgtggcttaa tgtcatatat aagcatcatc cagaattgac taaaagaatc
     3961 actactcatg gttttcgaca tactcatgcc tctctccttt ttgaatcagg agcttcttta
     4021 aaagatgttc aggaacgttt agggcatgca gacattcaaa ctacttcaaa tatttacact
     4081 catgtaactg aaactcaaaa caaaaaagtc atcaataatt ttgtagcatt tatgaagaac
     4141 agtactcagg gggagtcaaa aggggagtca aaaaacatt
//
LOCUS       DADQDV010000148         4151 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.153, whole genome shotgun sequence.
ACCESSION   DADQDV010000148 DADQDV010000000
VERSION     DADQDV010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4151)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4151)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4151
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.153"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..106
                     /locus_tag="J8S10_002999"
     CDS             <1..106
                     /locus_tag="J8S10_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAZ9631525.1"
                     /translation="ASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
     gene            970..1182
                     /locus_tag="J8S10_003000"
     CDS             970..1182
                     /locus_tag="J8S10_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631526.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPAELVS"
     gene            complement(1460..3259)
                     /locus_tag="J8S10_003001"
     CDS             complement(1460..3259)
                     /locus_tag="J8S10_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HAZ9631527.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
     gene            complement(3383..3979)
                     /locus_tag="J8S10_003002"
     CDS             complement(3383..3979)
                     /locus_tag="J8S10_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAZ9631528.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
BASE COUNT         1490 a          728 c          707 g         1226 t
ORIGIN      
        1 cgcatctaaa cgaaataata ttcctagaaa atcactggat tatcgaacac ctttggaagt
       61 atttttgagt tacgtaagta ttgatgatct gtctaactta atttgacaat taagattata
      121 ttaaatatta tacagataat aacggaatat tatcatcgaa acagctaaca aaattgtcat
      181 aaaaaacgag atggttgata ttagaacttg tgtttttgtt taggtctaga gataaagaga
      241 gacaatttcc aaatatatgt aatgaataca aaaagacgtt tgtcgcggat taccgttaca
      301 aacgtctttt attgattttc cgagatctca tcagtcgcca tttggaatgg ttcactcctt
      361 atctagattc gtttaatgct cggactgctt gttcgattgt aataccaaac gcaacgttat
      421 tttcgttttg tgcatcaatc gccataaaac ggttagaagt tgtatcaaaa gctacgcggt
      481 attgcatatt tgtttttgta aacgtcataa aattcatctc ctttgtaatg taatttagtt
      541 cttgaaagtt tcctttaaac tttcgaactt ataccaagtt tagcatcgta cgttttttga
      601 tgcaattaaa aagcatttat cattttcctt atttattttt tcttaaatgg tttagctatt
      661 ttcttttaat ccgataagta gcccaatcat caaggttaca aatactattg cttgaatata
      721 aatcatatgc tcacctcttt ataaataact tagcaatata aagaaaaaaa cgcacgaaca
      781 acataggaat ataaacaaac gtttttgtca caacgtctaa gatcgtgtta aaaaatagtt
      841 atctaaaaag cagaaagata ctcaaaataa aaaataaaaa aatggataaa aacgttttca
      901 aatacaaggt aatttgttat tataaaataa agaaaaaaca aaataaaaat aaagaaaaga
      961 gggaatgaaa tggtaaaagc agaagtagga agatcttata tatgcaaacc gatcggagta
     1021 tctcatgaac taatcggctg tattgaacgt acatatatca acacggctgt cgtgtatgtt
     1081 gaaagttatg accaacgaga ctatcaactt atcaatgaaa gcaagtatcg catgctcgta
     1141 aaattctgtg atattagcgc acctgctgaa ttggtttctt aaacagtatt tttgagaatt
     1201 cgcaagaact cccttataat ataaataaag acagaaggga gcgagaagat atgccaaaaa
     1261 gaaaaagttc agggaaaatg ggaattattc ttgcagtgat ctctgcaatt cctgctattt
     1321 tagctattgt tcgtgcgatg aaggaatcaa gagaaagtta agcacacatt atgagcgtca
     1381 aacaaaaaac gcatatacct gcggtggcag gttatgcgtt ttttgttgta taaagacttt
     1441 tttcattaac gatttttgat tagccgactc ccaaaacaaa atttagcagt ttatctgaat
     1501 aagtgatttc ttcatctgtt tgtttcacac tttcatttag tagtcccatc tcatcggtta
     1561 tgataccatc cacaccataa aacatcatgc gactcatagc atctgaatcg ttgattgtcc
     1621 atacatatac ttcttttccg tcttggtggg cagaattaat gaagttacgg ttgatcgtac
     1681 tatattccat tgtcagaaaa tcagcaggcg tcacaggggg cccaacaata ttgaaaggta
     1741 agatgtagcc cacataaaag tttggttctg cttcttttaa atctgaaacg gtttggtacg
     1801 tcaaactttg caaaatatga tggttctcta agataacttt gcggtattta tggacaaatc
     1861 gttcgacaag gtcatccgaa tcttttttag aggtcttgat ctcaataagt aatttttggt
     1921 ttagcttatg tgctttttcc aaataagaat caaaagaaca aacaggggct tgcactccgt
     1981 tttcagtaac tgtaagattt gtcaattctt tcaatgtaag atcctgtggt gttccattta
     2041 cccctgttaa gtgacgaaga tttgcatcat gcatcactac gaaatgacca tcttttgttt
     2101 cctgaacatc catctctaca taatcaggat gatagtctct gcttgttttt tcaagtgctt
     2161 ctaaagtatt ttgcgcccca ttttgggtac tcacacctct gtgagagaca gtcactggtt
     2221 ttgtctgaac agctgaagtc agataatcca tattgtaaag acagacgcca ataccgaaaa
     2281 aaactgcaaa aagagtcaaa ccagtgtttt tcagcgcaga gaaacgcaag ttgggggctt
     2341 gtgggataaa ccacttaggg atctcaggca agaagccttc gtcatccatg aaatcaacaa
     2401 tgatataaaa aatccctacg gtagacatca cgatattgaa taataaaatc ccttgtaaaa
     2461 gcgtcatagc aaacacagcg ctgatcaatg catagtctgg gaaaaattgt tcaaccatac
     2521 tttgtgccaa aataacaacg atatatccta aagaagaaag gagtaaaatc gtaccgccaa
     2581 tcacaataaa ttggcccgtg atggccaaaa gacgcgattt ggtcaatgac cagctttccc
     2641 gaatggctgc tcgaaaagga cgatctcgta gaatcatttc cggtaaagca aaaatcagtc
     2701 gaatcccaat atagccaagg aaaatataaa cgagtaaaaa ggaactgacg atgatccaac
     2761 gattagcaaa aataaaatcc ataatgaaag cggggatttt tatttttgac agtagatcag
     2821 aattaaaact taatccgctg atcggtagaa tcaataaaaa ataagcaagg aaaaacaaaa
     2881 aagtaatggg tctcactttc ttcagctgaa gtatcgtcaa gtgtaagagt tgcttcaaag
     2941 agattggttc tttcttttta ataaaaaaaa cactcatcaa aagaaaagta aattcgaaat
     3001 aaactaacag taaaatcgtc atcaaaacta cgattaacga gagtagaacc ccaggatgtt
     3061 gagaaaaaat tgaaggaata ttgtcataag acaaatagtc aattgcccct cggtgtaaaa
     3121 taaaacgggt cgtactgctc aataagggta aacaaataaa taaaataaag ccatgcatca
     3181 gcaagacatc acggaaataa gcttgtgttc cttttaaaaa gtcccaagca ttacctaagc
     3241 tacgtttcaa ataattcatc ctatcacctg ctcttcacat tgtagcgcaa atctaatgaa
     3301 aaaggaaagg gtgcagtgtg ttttgcagac cctttcccag atttaacatt gtcaatcaat
     3361 gactaatttt acaaaataaa tattatccaa gaagaccact tagatattga cctccataaa
     3421 tcaaggccat actatataag aaaatcgaca gtggtttagc aatcaaaatg attagtgtat
     3481 atcgtttcac tgacatgttt gtcaatccag ccatcaaaca taacgcatcg tcaggagcaa
     3541 ctggaagaaa aatagctaga gcaaacagct tctcaaaacg gttttgatta tccagccagc
     3601 caatatattt gttatatgtc ttatcgctaa tcatggaaag tatgaatggc tttccataac
     3661 gacgccctag cagaaaaatg ataatcgaac caatgcagat tccaatatag ttatagataa
     3721 atccagcata agggccaaat atcaggacac cagctgcagt actgatccct ccaggaatga
     3781 ttggaataac tacttgcagg atttggatga agacaaaaat aatcggtcct aaaatgatgg
     3841 aatcacctac taatcctctt aacgcattca aatctttgaa aacacctaaa ttaataaaat
     3901 aaatcgtcag cgcgattgat aggcctaatc cgataatgga tatgaaattt atcagttttc
     3961 gagaggcagc aatattcatt attcatcaac tccttagagg ttctttgtta actatacttt
     4021 actagaaaag caactaactg cgccattttt tgatatgaca gaaaacaaac aattttgtaa
     4081 gttcatcata agtataaaag attgatctca aaaaaacatc caactaaaga cttatttaat
     4141 aacttgtttt t
//
LOCUS       DADQDV010000149         4067 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.154, whole genome shotgun sequence.
ACCESSION   DADQDV010000149 DADQDV010000000
VERSION     DADQDV010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4067)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4067)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4067
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.154"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            86..1435
                     /locus_tag="J8S10_003003"
     CDS             86..1435
                     /locus_tag="J8S10_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAZ9631529.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(1563..2153)
                     /locus_tag="J8S10_003004"
     CDS             complement(1563..2153)
                     /locus_tag="J8S10_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HAZ9631530.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVLVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            2300..3652
                     /gene="brnQ"
                     /locus_tag="J8S10_003005"
     CDS             2300..3652
                     /gene="brnQ"
                     /locus_tag="J8S10_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HAZ9631531.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         1173 a          744 c          789 g         1361 t
ORIGIN      
        1 aaaattttgg aatcttagtt gtgtttttca gaaaactctc ttaatatgga agtaattaaa
       61 cttttttagt taggatgatt taaaaatgaa tgaagagcaa gaactgcagc gtggactgaa
      121 aaatagacat gtccaactga tttctattgg cggagcgatt ggaacggggt tgtttttagg
      181 ttccggaaag tctatccagc tagctggccc ttcgatattg ctcgcctatc ttattactgg
      241 atgcatctgt tttttcatta tgcgtgcgtt aggcgaactt ctgttatcaa acaccaataa
      301 ccattctttt ctggattttg ttgcagaata tcttggcaaa aaagcggctt tcatcactgg
      361 ctggacgtat tggttctgct gggtatcgat tgcaatggcc gatttaacag ccatcggaat
      421 gtatgtacgc tactgggcgc ctggtgttcc tcagtggctt cctgaactga ttgcattagg
      481 tcttcttctt tgcttgaata tggtggctgt ctcattgttt ggtgagttag agttttggtt
      541 tgcattgatc aaagttgtag cgatcattgc ctttatcctc gtaggagctt atatgatcct
      601 cacccactat acgacagata ttggcacagc cagtatcacg aatctatggt ctcatggcgg
      661 attctttcca actggtgcaa aaggatttat cttagctttc caaatggtaa cctttgcttt
      721 tgctgggata gaattagttg gattagtcgc tggagaaaca gaaaatcctg aaaaagtgtt
      781 gccggaagct atcaataata ttcctatcag gatcatctta ttttacttag gatctctttt
      841 tgtcattatg gcaatctatc catggaacag cttgaatcca gataacagtc catttgtaga
      901 agtattttcg gaaattggga tcacgattgc tgcttccttg atcaatttag tcgtattaag
      961 tgcagcagct tctgcctgca acagtgcaat atatagtaca ggacgtatgc ttcgttcttt
     1021 agcgcaagaa ggcagtgccc ctaaaaaatt caaaaagtta acaacacatc atgtgccagg
     1081 gaatgctttg acattttcta ctatcgtcat tttcatttct gttatcttga attacgtgat
     1141 gcctagtgaa gtattcacac tagtaagcag tattgccact acttgtttct tgtttatctg
     1201 gagtatgctt gtctacacgc acatgaaata tcgtaaaagt atcctcggca aaaaagctca
     1261 ttcatttaaa atgccgttgt acccatttag taattatctg gtatttcttt acatggcctt
     1321 tgtgtgtgtc gtcttgttcc taggaaaaga tacgagaatc gctttattac taacacctgt
     1381 gtggttcttg cttctattac taatctatca tatgaaatat gaacgtaaga agtaagaaag
     1441 tagttgtgac agaagtggtc agcttcgaga aataagaagg aatttacgaa aattgcttct
     1501 taaatttttg tgaaatttcg gcttatttct tggagataaa agcttctgtc ccagcctctt
     1561 ttctatttcc ccggaaacaa ccgctgataa taggcatctg cttttttata ggaaaaaatc
     1621 caaataccag atacaaaaaa acgtccgaat aacccgatca acggtacaaa aaagacaccg
     1681 gcaatcaagc ataagttaat catcatggag ataagacttc gacggtcctt tgacaaaact
     1741 ctcacgacat gggaatctgg tttatttgct ttcatgattt gcctcatcaa gataccaaaa
     1801 gaaaaactcc acatcgtgta tactaagaca taagccatct caggccaaaa agcttcaggg
     1861 ttacgcccga cccaactagt aacagaagga cataaagtca gccaaaagag caaaaagata
     1921 ttcgaccaga ccactcggta attaattcgt tctgccatct gaaatatacg atgatggttc
     1981 acccagatca ccgcaacaaa tataaagctg atggtataag ctaataatgt atttcggatg
     2041 acccataaag aatgaaagct agatgtatta gggatcttga tctctaatac aagaactctc
     2101 aaaacaatgg ctaccactcc atcagtaaat gcttctaatc tcgactttgt cacgatgatt
     2161 cctcctcaga tgattcagcg cttttatttt atcacttacg ttattaaata accatcgttt
     2221 tatataggga attttctgaa aattgttgca tatttttcga aattttgtta cttttaaaaa
     2281 aaccgtaaag gagttatgta tgacaaaaaa attatcattt aaagactatc tttttatagg
     2341 ctccatgctt ttcggtctat tttttggtgc tggaaatctt atctttcccg ttcatttggg
     2401 tcaagaagca ggcgctgcta ccttttgggc gaatctaggt ttcttggtta ccggtatcgg
     2461 tcttcccttc ttaggggtga ttgccattgg tgtatcgaaa agctcaggtg tatatgaatt
     2521 agcaaaacgg ataaatcaaa catatgcgat ggtttttacc atcttgcttt acttagttat
     2581 cggaccgttt tttgctttac ctcgccttgc aaccacatct ttcgagattg gtttagcacc
     2641 atttatcgat cctagcagac agacgctata tctagcaatt ttcagtattg tattttttgt
     2701 gctggcttgg tggttttcaa gaaaaccgac aaagatatta gattatgttg gaaagttcct
     2761 gaatcctgca tttttggttt tattaggtgc tttgcttctc cttgcttttt tgaatccact
     2821 aggttctgta aatcaagcgc ctattcagcc aaattatcaa gagcatgctt ttttcacagg
     2881 gtttactcaa ggatataaca cattagatgc gcttgctgct ttagcatttg ggatcatcat
     2941 tgtcacaaca atccaaaaca tgggtgtaac aaaacctgct gaaatcgcta aagacacgat
     3001 caaatctggt gcgatcagca ttatattgat gggaatcatt tatactttgc tcgcttattt
     3061 aggtgctatg agcttaggta gctttgctct aagtgaaaat ggcgggatca cgctggctca
     3121 gattgctgat cattatttag gtacttatgg cagtatctta ttagcattta tcgttatatt
     3181 agcttgcttg aagaccggta ttggtttgat tacagctttt gcagaaacat tcacagattt
     3241 gtttccgcaa agaaattacg cattctttgt tgcacttgct agtatccttc cttgtttagc
     3301 ggcaaacgta ggcttgacga atatcattca attttcgttg cctgttttga tgttcatcta
     3361 tccattagca atgacactga ttttactagt gttagttggt cctttgttta agcagcgtac
     3421 ggctgtttat cgaatgacta cttattttac attgattgct tcgatttttg atgggttgaa
     3481 cgcttgccca gaaactatca aacaaacacc tattgttcaa aatcttttat atgttgcgga
     3541 aagctacttg ccgtttttca aattggggat ggggtggatc gtaccagcag ttatcggttt
     3601 tgttatcgga ctgatttgga gtttcgctaa gaaagaagaa gtagcagatt gataaaagag
     3661 gttgtgaaag agacgttcag ccttgagcaa taaaaagtaa ttttgaaaaa tggcttctca
     3721 catttttgca taaatttgac ttaataccga gaaactgact tttgaacacc gtttattgag
     3781 aggtcgtgaa aaagccgctt agtttcaagt attaagaaat attttgtgaa aatggcttct
     3841 cacatttttg cataaatttg acttaatacc gagaaactgg cttttgaaca ccgtttattg
     3901 agcgtctata aactgacctg agtattagag aaacaaaacg gcaaagtagc tccatatact
     3961 ttgccgtttt gttttgaact aataccgaag agaagctgat caaacaacat ttcttttata
     4021 atatagattt tagacatata tatgatataa aaatagtttt cgcaaaa
//
LOCUS       DADQDV010000150         3924 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.156, whole genome shotgun sequence.
ACCESSION   DADQDV010000150 DADQDV010000000
VERSION     DADQDV010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3924)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3924)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3924
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.156"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(573..1130)
                     /locus_tag="J8S10_003006"
     CDS             complement(573..1130)
                     /locus_tag="J8S10_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631532.1"
                     /translation="MRNLSNRNKILIIIVVIAVFHLGTNAVLSRIILGPKPPRPEITR
                     GEFDFRLEYEVDGERIVIEDTIVALFDGFSADAGSMAWYRTWRLHLASDRRSRNILLD
                     ELEDGRRIYYVPESANYSMGDVQKKREPNPNWYPFNGVTIEYPRNKTPEIGAKFISGL
                     EDLYDRFGIRLISWEHDPPIENRFE"
     gene            complement(1309..1920)
                     /locus_tag="J8S10_003007"
     CDS             complement(1309..1920)
                     /locus_tag="J8S10_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631533.1"
                     /translation="MNSNRGNKMEYNGSMRIVQIIFWITSGIVIIGGVFLMLPSLIFP
                     FFALISPKIPEPEITYGEFPFRIEYELDGQINIIEDTVIAEFNGCEFSAGSMKRERRW
                     RSRLASGREDLPFGDDLGIYFSRGSAQYYMGENVQSMSLKPHIALRNLEEGFKREVDF
                     ILGESGYIRTVLNFGEAQEVLTQYGITLINWEISEPIVNNFGD"
     gene            complement(2033..2290)
                     /locus_tag="J8S10_003008"
     CDS             complement(2033..2290)
                     /locus_tag="J8S10_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631534.1"
                     /translation="MRAVHVNPTIEITMIGHSKGGAEAANSVAINTNAIIFNPATVNL
                     SAYELDSNTYTANMVAYVVEGDALNVVFGGVYTYWRINHVR"
     gene            complement(2887..3165)
                     /locus_tag="J8S10_003009"
     CDS             complement(2887..3165)
                     /locus_tag="J8S10_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631535.1"
                     /translation="MEKHNITGSMYVDDQWFISTDEVKIAAIRRDYLQKIHKIKDPNG
                     KKARLIITLITSNGKKLKLAGSYDNVKKFEHWYLQKDSISLNKQFEKN"
     gene            complement(3199..3450)
                     /locus_tag="J8S10_003010"
     CDS             complement(3199..3450)
                     /locus_tag="J8S10_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631536.1"
                     /translation="MKEKPINKWSLYKNSMFGVVIFGVCAGLFLFILLQTVTLFSSNP
                     TYGWRDSIALGMFAGGYGFLLLFSILTLSPIHGLIQLWK"
BASE COUNT         1195 a          799 c          520 g         1410 t
ORIGIN      
        1 ttattccgaa taaatggtgt ccaaaagctt gcatctgcca gattatctca tttcttatga
       61 caagctaagc aaattatctc caccaaataa tttattcata tttttgactt gcgcatacta
      121 actaattctt aaattttcat acaaaatttc tcaatttccc ttaacgagta atatttatgt
      181 acggtgattc tcactagtat cccaatcact ttttaagtta tcccgatttc aattctactt
      241 caaaaatagt tgcttttatg tatgctgtta gttgattaga tggtcatttg ttgagctagg
      301 tcgtttattt taaacaagtt gtttctttag cttataccta tctcgtctac caaacgcaag
      361 atggcaaaca caaatgcata cgcatctgta tttgccactt tgattcgtat aaagctaaca
      421 actattaact cctctcagct aatagttgct ctctttttta ttcagattca tttttgctga
      481 tcacagccta gtatttcaat ggttttgaac actaaaccaa attgttccat tacaacattc
      541 actggctgat gaaatggatt agtagatttc gattattcaa agcgattttc tattggtgga
      601 tcgtgttccc aactaataag acggattcca aacctatcgt acagatcttc taaaccactt
      661 ataaattttg cacctatttc aggtgtttta ttgcgtggat attctattgt tacgccatta
      721 aatggatacc aattaggatt aggctctctt tttttctgta catctcccat agaatagtta
      781 gcactttctg ggacataata tattcttcga ccatcctcta attcatctaa taagatattt
      841 cgtgatcgtc tatcacttgc taaatgtaga cgccacgtgc gataccatgc catgctacct
      901 gcatctgcag aaaatccatc aaataatgca acaattgtat cttctatcac aatcctttcc
      961 ccatctactt catattctaa tctaaaatca aactcccctc gggtaatttc tggtcttggt
     1021 ggcttaggac ccaatattat tctacttaaa accgcattcg ttcccagatg aaacacagct
     1081 ataacaacaa taatgattaa tattttgttt ctatttgata aatttctcat tattcgcaca
     1141 tcacctctac attctcacat attagttcgt aatactcctt taatatcaaa atatctactg
     1201 gtcgtaataa tattcgctat gaattcctac tactcgtata agaaaggcca aatcatcagc
     1261 ttttacttgc tgatgatttg gcttgtttct atttatcgta attgttttct aatcaccaaa
     1321 attgttaaca atcggttcag atatttccca gttgattaag gtaattccgt attgtgtcaa
     1381 aacttcttgc gcttctccga aattaagtac agttcttatg tatccacttt ctcctaatat
     1441 aaagtctacc tctcttttaa aaccttcctc gagatttcta agggctatat gtggttttaa
     1501 tgacattgat tgtacatttt cccccatata atattgcgca cttcctcgac taaaatagat
     1561 tcctagatcg tccccaaaag gtagatcttc tctaccacta gctaatctac ttctccatct
     1621 tcgttctctt ttcatagaac ctgcgctgaa ctcacacccg ttaaactcag ctatgacagt
     1681 atcttcaatt atgttaatct gtccatctag ttcgtattca atcctaaatg gaaattctcc
     1741 ataggtgatt tccggttcgg gtattttagg tgagattaat gcaaagaaag gaaatattaa
     1801 gcttggcaac atcaaaaaaa ctcctcctat gatcacaatt cccgatgtaa tccaaaatat
     1861 aatttgtaca attctcattg atccattgta ttccatttta ttccccctat tactattcat
     1921 atccgcctat ctatatcgat cttccaatgc agagataatt gcttccatac cttgattttt
     1981 tactgagtta cctatgcgag atatcattct ccactaaggt gcatcatatt gtctatctaa
     2041 catgattaat tctccaatag gtgtatactc ctccaaaaac aacatttaat gcatctccct
     2101 cgacaacata agctaccatg tttgctgtat atgtgtttga gtctaattca taagcagata
     2161 aatttactgt cgctggatta aatataatcg cattcgtatt tatagctact gaatttgctg
     2221 cttcagcacc accttttgaa tgtccgatca ttgtgatttc aatagtagga tttacgtgga
     2281 cagccctcac cgtttaccct gaccattata gaaatcgctt acttttttga actacgcaac
     2341 aaaggataca atgctcctaa cttcactgtc tccatttttg tccactaagg aatataaaaa
     2401 ataggcatta attcatttaa ttcggtcaca acacgttacc ttttaaatca ttatactgta
     2461 tctcatacat tattatcaat aaactattat aaaaatgcaa aaaatgcttt atcaatctat
     2521 tttgtaattg gtcataatat cattgaaatc ataccctgta tcgatttttc ctatgaatct
     2581 cgtctatttg tgattgacga aaaagaggca agacagacac tggaatggta attttaccca
     2641 ctattttgct ccaactattt gtaatcgtac ccacttttga aataccgaga tgatcatttt
     2701 aattgatatg ctgattccca agcaaaaccc caagaaatta aatgctctat cgcatctagc
     2761 ttcttgggtt ttgcttatat aaattccaac atttaaattt tttatgctgt tcggtctcag
     2821 aaatgccgtt tttgcttata tcacaatatc aagatgtcaa attattcgtg ttgccgatga
     2881 ctttgattaa tttttttcaa attgtttatt aagactaatg ctgtcttttt gcagatacca
     2941 atgttcgaac tttttaacat tatcatatga tcctgcaagt tttaacttct taccattaga
     3001 tgttatcaaa gttataatta accttgcctt tttcccatta ggatctttta ttttatgaat
     3061 tttctgcagg taatctctcc taatggcagc tatttttacc tcatcagtgc tgataaacca
     3121 ttgatcatcc acatacatac tgcctgttat gttgtgtttt tccatttctt ccgagaacga
     3181 aaagtttaag gctcgttctt acttccaaag ttgaatgagt ccatggattg gacttagtgt
     3241 gagaattgag aacaacaata agaatccata tcctcccgca aacatcccta aggctatact
     3301 gtctctccat ccataagtag gattagaaga gaaaagagtc accgtttgta ataatatgaa
     3361 aaggaataat ccagcacaaa caccaaagat aacaactcca aacattgaat ttttatacaa
     3421 tgaccattta tttataggct tttctttcat tttacttccc cctactgttc tgttcacacg
     3481 gaatgaattc aaagttcata agccctcctc tttgaacata tgaatacgac ttgctaacta
     3541 tactttaaaa aagcttgttt taagcggtta taggcgagtt gtaatctcta ttcatctcat
     3601 tagcaaataa cttgccgaaa agtctactga aattaaagca gatagtggaa gaattattta
     3661 gccaggatag acactatttg tgaaacacat gtctttactt ttgaaattct atgatgaaaa
     3721 gccttggaat acagtagctc ttaattggta atactttttc cattataaat aacctctttt
     3781 cattttatat ttatcccctc taaaaataat atctaatcta atattttaaa cttatatttc
     3841 cctcgctgtg ctaatagagc attactaaat aaatagaaac tagaaaaaag cattacgcct
     3901 gccagaataa accaattatt tgta
//
LOCUS       DADQDV010000151         3920 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.157, whole genome shotgun sequence.
ACCESSION   DADQDV010000151 DADQDV010000000
VERSION     DADQDV010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3920)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3920)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3920
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.157"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(474..773)
                     /locus_tag="J8S10_003011"
     CDS             complement(474..773)
                     /locus_tag="J8S10_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631537.1"
                     /translation="MLFNETQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINLY
                     YSNKNYFKIPAAKTRMKKDVYFLFDIVTDVLDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(779..1009)
                     /locus_tag="J8S10_003012"
     CDS             complement(779..1009)
                     /locus_tag="J8S10_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631538.1"
                     /translation="MMEEFIRKNISDEYADFYDQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETKFKNRSE"
     gene            complement(1445..2011)
                     /locus_tag="J8S10_003013"
     CDS             complement(1445..2011)
                     /locus_tag="J8S10_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAZ9631539.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(2011..2967)
                     /locus_tag="J8S10_003014"
     CDS             complement(2011..2967)
                     /locus_tag="J8S10_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HAZ9631540.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(2967..3623)
                     /locus_tag="J8S10_003015"
     CDS             complement(2967..3623)
                     /locus_tag="J8S10_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HAZ9631541.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
BASE COUNT         1258 a          730 c          665 g         1267 t
ORIGIN      
        1 aagagtatta tacaagctaa agcttttctt cattgccact caaatgagtg gcttttttat
       61 gtatcctttt atggattaat gaaaggatgt ttcacatagt tatatttctg tatatttgaa
      121 aagttttact ttgattttta aatagaaaga catttgggtt atattgtgag ataataataa
      181 agaagagttt aaagcgttcc ccaaaaacca ctgccccata agtgtgttac gctttaaact
      241 cttttatatt tgaagccatt aaaaagcata ccatattttt gaaaaaaagt gagaaaaaag
      301 gcttataatt ggagtggtag ttaattagtg acttattttt gattttatag cactgatact
      361 ataaaatata gatatcatca tattacacaa tcttaatact aacttaaaaa atatctcctt
      421 tcataagtat ggtgataaaa tccgttccgg gctacctttt taggtagcct actttaatct
      481 ttgtatcttt ctggatcaac gaaagtatac tttatatagt cataacgccg atgatcgctt
      541 cgagcgtcta gcacatcagt cacgatatca aacaaaaaat atacgtcttt cttcattcta
      601 gttttcgcag cagggatttt aaagtagttc ttattagaat agtagagatt aattaataag
      661 ctatcttcga ttgctaaaaa gaaaacttct gaatcccaca ccttataaaa atctttgaca
      721 aatctattcg aaggatcaaa tttaaaccat aattgcgtct cattaaaaag cataaccatt
      781 actccgatct atttttaaac ttagtctcta cctctaatat atatcgagtt tttattttgc
      841 cttcagagaa tactgtttct ttttttgcag ttacaggttg tttattttcg gaaaaagcta
      901 atatagctaa aattgaaaca tccatctgga atttatcttt tttactgctt tgatcataaa
      961 agtctgcata ttcatcactg atattttttc taataaattc ttccatcata aaaatcacct
     1021 caaaacgatt atacgaactt acgttcttgt tgtaaagcga tatttgaggg gcaaaaaagg
     1081 ggcataattt gactgatatt aagttagcta ttgatatatg aatgacatac aaaaatataa
     1141 aatcttttaa aaatgcttat atatcaatgt ttttgccatt cttttatata tctgttatat
     1201 gtcaaaaaaa tgtgttcaat ttcaatttgt atttgaataa agaggttgtg aaaaagctgt
     1261 cctgcatcaa gtaataagaa cagccaatca aaaacagctt ctcatgtttt tgatttggtt
     1321 ggacttatta ccgcagatat aagcttttga gcaccgtgaa taaagaggtt atgaaatcaa
     1381 cgctctaacc tgagtattag agaaaaaaac gcaaaacata tcatttatgt tttgcgtttt
     1441 ttatttatct ttttttctca atacaatata aaataggcgg ctggttcttt tggttgataa
     1501 accgataatt cagcacatta tatgtttcct gtggcagttt ggaacaaaaa gaatcaacca
     1561 tatccagttc tttttctcca ccttcatgac catagtagac gacaaggatc aatcgtccgc
     1621 gaggcacaag tcgtttcaat atttcttcca tagctgtgcg tgtagtctct ggcatagtga
     1681 tgattgcttt atcacttttt gggagatacc ctagattgaa aatccctgct ttgagatttt
     1741 gttgttcagc tatcacttct cctaacgttt cgtggccttg tagaaacaat gagacacgtt
     1801 cttctaactg acgctgttct agcctttcac gagtagcatc gattgcttgt tgctggatat
     1861 caaaactata gacatgacca gtttttccga tgtgttctgc tagaaaaacc gtatcgtggc
     1921 cattgcccat cgttgcatct acgacgtgat cccctggttg caagatttct tgcagtaatg
     1981 tatggctgaa atgcaaagca gtttgcaaca tcagacgctc acctttttcc gtacatcata
     2041 ttttccttgg aagctatctc tgcgaagaag ttcttcatca attgcattca agacttccca
     2101 ttttttcaag ctccacattg gtccaatcaa ggaatcccac ggcgcatccc ctgtcaaacg
     2161 atggatgatg atctcttttg gtatcatttc cagctggtcg caaatgacat tgacatagtc
     2221 aggacggctc attaattgaa ggcgaccttc atgatagtcc cgcaacattc tcgttttgcg
     2281 catcagatgc atcaaatgga gcttgattcc ttggatatct gaatctaaaa tggtgcgtct
     2341 gacattttct ttcatcattt ctaaactttc gcctggtaat ccgttgatca aatgcgtaca
     2401 aacacggata ttatgtttgc gtaatttagc cacgccatct aaataagttt gataatcatg
     2461 tgctcggttg atcagttttg aagtttcttc aaaagttgtt tgcaatccaa gttctaccca
     2521 taaatacatc cgctcgttca gttcagcaag gtaatcaact acttcatctg gcagacaatc
     2581 cggtcgtgta ccgactgata atcctacgac acctggtaaa ttgactactt gctcaaatcg
     2641 ttctttgatt atttcaactg gcgcatgggt gtttgtaaaa ttttggaaat aaacgatgta
     2701 ttgttggaca tgaggccatt tttgatgcat catgtcgatt tctttctgga attggattgg
     2761 aagagggtct tcaggtgcaa cgatcatgtc tcccgaacca gatacactgc aaaaagtaca
     2821 accgccatgg gcaacagtcc catctcgatt cggacagtca aatcctccat cgatcggcac
     2881 cttgaaaatt ttcccgccaa actcatttcg taaagcgtaa ttccaagaat gatatctttt
     2941 atttccttct gaataaggaa aagtcattaa aagtccttct ttctgtaaga gttatctatt
     3001 tgttttcttt tttctctata cactggataa gtcaggcaca gccaagaaag actgagtaag
     3061 tagccgccga tgatatcagt aggaaaatga acgcccagat aaatgcggct tatcccgaca
     3121 cttactataa taaacatcat cagcaattga agcaatgtgc gtaaggttct tttttgaaca
     3181 aaagctggaa gcagaaatag taaagaaccg taaagaatca tactgcctgc tgcatgtcca
     3241 ctagggaaac tgtaacttgt ttcaactact aagtgcgcca atgaaggacg ctctcgcatg
     3301 aaaaatagtt tgatcaccgg gttgatgatt ccagcaatta caataaatcc agaaacgaac
     3361 caaaatgttt ctgccctttt tttcttatac cacatccata aagccgcaca agcaaataaa
     3421 atgatgacgg taagaggatt accgaattta gtcataaaga gttggtagct gttcagatca
     3481 ggataagaag ctctgacaat gcctgtaaac cactgatcga aaccagaaag ccacgacaga
     3541 tggaacttta cgatccagcc caaaatgaaa aacaggacaa gaaagaagct accagccacc
     3601 tgaaatgatg ttttatattt catacaattc ctcctttgaa gcaatgactt attatagcat
     3661 ttttggtcca gcgaaaaaaa cggtaaagag ataaaaccaa tgtatgattc ctctttgaat
     3721 aaccaatatt cttataaaaa aaataactgt aatcggaaag acattttttg gtaatgcaaa
     3781 tgaaatgtta gggaaataaa atcagtgttt ttcgaaatcc ttttaaacaa gaacgtagac
     3841 gtaggaagaa cttgaaaatg aacagaagtt gttcattacg gtaaattaca atatgattac
     3901 aaaaaacaac aaagctctta
//
LOCUS       DADQDV010000152         3908 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.158, whole genome shotgun sequence.
ACCESSION   DADQDV010000152 DADQDV010000000
VERSION     DADQDV010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3908)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3908)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3908
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.158"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            35..769
                     /locus_tag="J8S10_003016"
     CDS             35..769
                     /locus_tag="J8S10_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008766909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAZ9631542.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            802..1710
                     /locus_tag="J8S10_003017"
     CDS             802..1710
                     /locus_tag="J8S10_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HAZ9631543.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            1707..2249
                     /gene="sat4"
                     /locus_tag="J8S10_003018"
     CDS             1707..2249
                     /gene="sat4"
                     /locus_tag="J8S10_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HAZ9631544.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            2342..3136
                     /locus_tag="J8S10_003019"
                     /note="aph(3')-IIIa"
     CDS             2342..3136
                     /locus_tag="J8S10_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HAZ9631545.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            complement(3244..3432)
                     /locus_tag="J8S10_003020"
                     /pseudo
     CDS             complement(3244..3432)
                     /locus_tag="J8S10_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913594.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3412..>3908
                     /locus_tag="J8S10_003021"
     CDS             3412..>3908
                     /locus_tag="J8S10_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAZ9631546.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLE
                     EAGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAM
                     YKIKSILKHGEKNYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPA
                     SGGQEP"
BASE COUNT         1334 a          596 c          906 g         1072 t
ORIGIN      
        1 gagataaata actttttaaa cgaggagagt tcagatgaaa gaaaacaaat atgatgataa
       61 tatatttttt caaaaataca gtcaaatgag tcgctcgcag aaaggactgg ctggtgcggg
      121 agaatgggag actttgaaaa agatgctacc tgattttaag ggtaagcgtg tgcttgattt
      181 aggatgcggc tatggatggc actgtatata tgcgatggaa aacggtgctt cctctgtagt
      241 aggtgttgat atttctcata aaatgctcga agtagcaaaa ggaaaaaccc attttccaca
      301 gattgaatat gaatgctgtg ccatagaaga tgtggatttc ccagaggaga gctttgatgt
      361 aatactaagt tcgcttgcgt ttcattatgt agcagactat gagaatttaa taaaaaagat
      421 atataggatg ctgaaggctg gtggcaattt agtttttaca gttgaacatc ctgtttttac
      481 tgctcatgga acacaagact ggtattataa cgaaaaagga gaaatactgc atttcccggt
      541 ggacaattat tattatgagg gcaaacggac agctatgttt ttggaagaaa aggttacaaa
      601 atatcataga acactgacca catatctaaa tacactgctt tcaaatagtt ttataataaa
      661 tcagattgtg gagccacagc cgccagagaa catgatggat attccgggga tggcggatga
      721 aatgcgacgc ccaatgatgc tgattgtatc ggcaaaaaag aagatgtaat aatatagaaa
      781 aaataaacga ggagtatgta aatgagatca gaaaaagaaa tgatggattt agtactttct
      841 ttagcagaac aggatgaacg tattcgaatt gtgacccttg aggggtcacg cgcaaatatt
      901 aatataccta aagatgaatt tcaggattat gatattacat attttgtaag tgatatagaa
      961 ccgtttatat ctaatgatga ctggcttaat caatttggga atataataat gatgcaaaag
     1021 ccggaggata tggaattatt cccacctgaa gaaaagggat tttcctatct tatgctattt
     1081 gatgattaca ataaaattga tcttacctta ttgcccttgg aagagttaga taattaccta
     1141 aagggcgata aattaataaa ggttctaatt gataaagatt gtagaattaa aagggacata
     1201 gttccgactg atatagatta tcatgtaaga aagccaagcg caagggagta tgatgattgc
     1261 tgcaatgaat tttggaatgt aacaccttat gttattaaag gattgtgccg taaggaaatt
     1321 ttatttgcta ttgatcattt taatcagatt gttcgccatg agctgctgag aatgatatca
     1381 tggaaggtcg gcatcgaaac aggctttaaa ttaagtgtag gcaagaacta taagtttatt
     1441 gaaaggtata tatccgagga tttgtgggag aaacttttgt ccacctaccg gatggattcc
     1501 tatgaaaaca tatgggaagc attatttcta tgccatcaat tgttcagggc ggtatccggt
     1561 gaggtggcgg aaaggcttca ttatgcctat ccggagtatg ataggaatat aacaaaatat
     1621 accagggaca tgtataaaaa atacactggt aaaaccggct gcctggatag cacatatgcc
     1681 gctgatatag aagagaggcg ggaacagtga ttacagaaat gaaagcaggg cacctgaaag
     1741 atatcgataa acccagcgaa ccatttgagg tgataggtaa gattataccg aggtatgaaa
     1801 acgagaattg gacctttaca gaattactct atgaagcgcc atatttaaaa agctaccaag
     1861 acgaagagga tgaagaggat gaggaggcag attgccttga atatattgac aatactgata
     1921 agataatata tctttactac caagacgata aatgcgtcgg aaaagttaaa ctgcgaaaaa
     1981 attggaaccg gtacgcttat atagaagata tcgccgtatg taaggatttc agggggcaag
     2041 gcataggcag cgcgcttatc aatatatcta tagaatgggc aaagcataaa aacttgcatg
     2101 gactaatgct tgaaacccag gacaataacc ttatagcttg taaattctat cataattgtg
     2161 gtttcaaaat cggctccgtc gatactatgt tatacgccaa ctttgaaaac aactttgaaa
     2221 aagctgtttt ctggtattta aggttttaga atgcaaggaa cagtgaattg gagttcgtct
     2281 tgttataatt agcttcttgg ggtatcttta aatactgtag aaaagaggaa ggaaataata
     2341 aatggctaaa atgagaatat caccggaatt gaaaaaactg atcgaaaaat accgctgcgt
     2401 aaaagatacg gaaggaatgt ctcctgctaa ggtatataag ctggtgggag aaaatgaaaa
     2461 cctatattta aaaatgacgg acagccggta taaagggacc acctatgatg tggaacggga
     2521 aaaggacatg atgctatggc tggaaggaaa gctgcctgtt ccaaaggtcc tgcactttga
     2581 acggcatgat ggctggagca atctgctcat gagtgaggcc gatggcgtcc tttgctcgga
     2641 agagtatgaa gatgaacaaa gccctgaaaa gattatcgag ctgtatgcgg agtgcatcag
     2701 gctctttcac tccatcgaca tatcggattg tccctatacg aatagcttag acagccgatt
     2761 agccgaattg gattacttac tgaataacga tctggccgat gtggattgcg aaaactggga
     2821 agaagacact ccatttaaag atccgcgcga gctgtatgat tttttaaaga cggaaaagcc
     2881 cgaagaggaa cttgtctttt cccacggcga cctgggagac agcaacatct ttgtgaaaga
     2941 tggcaaagta agtggcttta ttgatcttgg gagaagcggc agggcggaca agtggtatga
     3001 cattgccttc tgcgtccggt cgatcaggga ggatatcggg gaagaacagt atgtcgagct
     3061 attttttgac ttactgggga tcaagcctga ttgggagaaa ataaaatatt atattttact
     3121 ggatgaattg ttttagtacc tagatttaga tgtctaaaaa gctttaacta caagcttttt
     3181 agacatctaa tcttttctga agtacatccg caactgtcca tactctgatg ttttatatct
     3241 tttctaaaag ttcgctagat agagttctat attagagatg taaagagttt tggtgaagag
     3301 gtttgtgagt atggctttta taaccagggt gcaatgagaa gcactaacag cagctagctt
     3361 aagaacgcat aggatatact ttttatggaa gtcacagagg aggaataaaa tttgaacagg
     3421 attaacagag taacctctat tcttattcag ctgcaatcaa aaaaaataat tcctgccaaa
     3481 gaaattgcac agcgatttaa tataagctta aggacagttt acagagatat ccggacactt
     3541 gaagaagccg gaataccaat tggatctgag gccggaaaag gatattttct tgtagagggc
     3601 ttcctacttc cgccggtaat gtttacagcg gcggaagtgg gtgcattgat tacagcaggg
     3661 aaatttttaa attgccatgg agatgaatca tttataaagg attttgattc agctatgtat
     3721 aaaatcaaat ctattttgaa gcatggtgaa aaaaactatg cacaggagtt ggagaacagt
     3781 attaacgtgt acagcacatc tggacagaaa aatacattgg cggataacgt tattgcagca
     3841 attcagactg caatctgcaa taaaagggta atatcaattc aatatcctgc atcaggaggg
     3901 caagaacc
//
LOCUS       DADQDV010000153         3794 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.160, whole genome shotgun sequence.
ACCESSION   DADQDV010000153 DADQDV010000000
VERSION     DADQDV010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3794)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3794)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3794
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.160"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            174..518
                     /locus_tag="J8S10_003022"
     CDS             174..518
                     /locus_tag="J8S10_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HAZ9631547.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVGWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            519..938
                     /locus_tag="J8S10_003023"
     CDS             519..938
                     /locus_tag="J8S10_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HAZ9631548.1"
                     /translation="MTTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVIFEPGCRNHWHVHKDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(1030..1380)
                     /locus_tag="J8S10_003024"
     CDS             complement(1030..1380)
                     /locus_tag="J8S10_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631549.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(1346..2677)
                     /locus_tag="J8S10_003025"
     CDS             complement(1346..2677)
                     /locus_tag="J8S10_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HAZ9631550.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGGFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSALSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGLLLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLLGIREIFDSSGKLTT
                     DFIANSGIGATLINIGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            2933..3499
                     /locus_tag="J8S10_003026"
     CDS             2933..3499
                     /locus_tag="J8S10_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAZ9631551.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            3644..3731
                     /locus_tag="J8S10_003027"
     tRNA            3644..3731
                     /locus_tag="J8S10_003027"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3676..3678,aa:Ser,seq:cga)
BASE COUNT         1398 a          648 c          732 g         1016 t
ORIGIN      
        1 aaataaaaaa agcgttagca actatgctta aaaagcatat cgactgaata aactaagcat
       61 tggacaggct gaaagactac atttaaaatg aaatgcgaag aaacaataga aaataaagtt
      121 gccttagaac catagttgaa tcacctaaca gtcgtgaagg gagaataaga gaaatggcag
      181 aaaaacaaac cgcaggacga gatcaattag gagattttgc accaaaattt gcagaattga
      241 atgatgatgt tttatttgga caagtatggt ccagagaaga attatctgct catcagcgta
      301 gtatcatcac catatctgca ttaatttcag gaggaaattt tgaacaattg ccagctcatc
      361 tgaagattgg caagcaaaat ggcattacta gtgaagaaat agcagaaatc attacccatt
      421 tagcttttta tgtaggatgg ccaaaagctt ggtcagcttt tagtttagca aaagaaatct
      481 atttagaaga aaatagcgaa gataagaaag aggcgtaaat gacgacaaaa cacgaagaaa
      541 tacacaatgg cgtgattttt ccagcaggtg aaaaaaacga agcttacgct caagtattta
      601 ccgggcaaag ctatctgaat atgttagtga atgatcccga agtttctgtt ggtgtaggta
      661 atgtaatttt tgaaccaggt tgtcgcaatc actggcatgt ccataaagac ggctatcaaa
      721 tcttacttgt gaccggagga gaaggctggt atcaggaaga aggaaagcca gcaagacgat
      781 taatggctgg agatgtcgtc gtaacgcaca aagggattaa acattggcat ggtgcgacaa
      841 aagacagttg gtttgaacat ttggcgatca ctgctggtaa ttcagagttt ttagaacctg
      901 taacagatga agtgtatgaa ggattggaaa atcaataatg tcaagcttga acagctcctg
      961 aaagtagatt ttaatcgaac tttcaggagc tgcttttttg attcagtctt ttataaatag
     1021 aaaatagggt taataatagg aatgagaagc acgtcgaaag atcttaatat tgataatcgg
     1081 ctgggcatac atgatttcca cgtcatcaat caaactacct aacagatgat aatcttcccg
     1141 atcatgtcgg ggattaccta atagttcttg atagtagatt tccatactag ggtcccgagg
     1201 attgttcagc aaatcagcaa gtacatctaa atcttctggc tgagtttctg ccgtaccctg
     1261 tatctctatg aaaagccctt cctcagcaaa ttctactcca atacgtattt cagttatttc
     1321 atgggaatat aaataagtaa gaagctcatc gatgattctt tttgataatt ctttttccaa
     1381 gtgtcttttt ttcctttctg acagcggtaa agttatctag tatcggtaca aggatacctg
     1441 caacgaaacc agttgaaaaa ccactgttat atagatttag tcctccgtgc aaagtgctga
     1501 cgttatggac aagagcaata tgtagtacac cagctattac accgtaaaaa ctgccgtaaa
     1561 aaccgcttat gggcgcgaga cctgtcccaa acacagctgc aacaagcatg ccagtactgg
     1621 tgatctcatg aaaagttcca aacaaagaag caataaatat tccgactagt atcggaaaac
     1681 tgttttttaa atgacaacca aaagcactga aacccaccgc agataaaata gcaccgatga
     1741 caggtccatt taactgaccg ccaaccagca aaacataaga agacagcatc agaccaacta
     1801 agcctatgtt gatcaaagta gcaccaatac cagaattagc aatgaaatca gttgtcaatt
     1861 ttccagatga atcgaaaatt tctcgaatcc ccaaaagccg aaaggaatta taatagaaac
     1921 caattccgac tgtcagcgaa aaaaagccaa aaataatcca aatgagagga aagtgatatt
     1981 cattgaaaac caatgtattt tcgacgattg aatagctgaa taacctcaaa acagcagtaa
     2041 aagtcatcgc aatcaaccca gaggtgaatc caatattata aagtgtgaat ccacgatgga
     2101 aaactaaagt ttgagcagct aagggcggaa gaagtagacc aattgctatg ccagctaaat
     2161 tccccaataa aatacctatc agtaaaggaa aacgcatacc aaaagtgata taactaacga
     2221 ccggtgataa tgcgctacca aacagtccga tcatgatgta ctgagaaaaa ggtttattga
     2281 caaatacagc gtatagatac acacctaaaa tgattgagat agaattataa aggtttttgc
     2341 caaaaaaaga gaaaccggta actgttagaa tcgaagcaaa taagggaccg tttaaaatca
     2401 ccttgtgccg ataagctaaa agcacagaaa gtaaggtcaa aatccctaca tttatgaatg
     2461 cgcttccgaa accgcctaaa gcaaaataat ctgtcaaaag attgcttggc gaggtaagaa
     2521 tagttagcaa tccactccaa ttatcagtag gagtattaga aagcaagcca ataaaaagaa
     2581 aaaaaacacc tgtaaaacca agataaaaat actttctttt ctgtgaaacg attcgttttt
     2641 gaggatgaat ataaataacg tcagtttcgt tttccattac acaccttctt tttcattttc
     2701 tttaactata acttgaaatg aaagatttgg acaactatca tttaggtcaa aactaaaaat
     2761 gtaagggaac ccattgaatt taaccaaatt tttttaattt tgcaaaaaaa agttaaagaa
     2821 gactgaaaaa aaatttaaaa tataacgttt tgagtaaaat gtttgcaaaa aatgctaaaa
     2881 atagggtaca ataaaacaac atatactgca gtaaagaagt gggggagttt taatgagaag
     2941 aaaagtctat accaaggatc aaattctaaa agctgcttat gatgttgttg caaaggaagg
     3001 gtttaaagga tttactgcga gaaatattgc taaaaagatg gggatttcga cacagccgat
     3061 ttatctggaa ttcaaaaaca tggaagattt aaaaaatacg ttgctggatt ctatctttga
     3121 acaactaaaa gaagatgttt tccctattga acgtactggt gataaaatca ttgatctcgg
     3181 tttgaactat atctactttg caaaaaagca tcatagtctt tacatggcat tgtacattga
     3241 tgaacatggg gacggaaaga aaatgcatga tttttcatac aattatttcc gtgaaatagt
     3301 taaagaagat gaaagataca atcaattatc ggatgaatat gtcgatgctc tgcatactgg
     3361 tacatgggta gcagtgactg gcttagcgtc attgatgtca tcaaacatca tgcatccaac
     3421 agaagaacaa atcattgcac tgatcaaacg gacaattgac tcgattttag cattagataa
     3481 tcctgaaata atcagatagt gttctatcag tatgaatttg atcggtaagt ccgttggctg
     3541 caaactgtca atggactttt ttgctaaaaa aagcgatttc tgttatttat ctattagaaa
     3601 taggcttgac atttcgtgaa aaaagtttaa aaatagtact tacggaaggt tggcagagtg
     3661 gtaatgcacc ggactcgaaa tccggcgaac cggctaatac cggcgcgcag gttcaaatcc
     3721 tgtaccttcc ttatatatca acgattagac acgatttcga tcgtgtcttt tttgttgtat
     3781 atttagccta aaat
//
LOCUS       DADQDV010000154         3699 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.161, whole genome shotgun sequence.
ACCESSION   DADQDV010000154 DADQDV010000000
VERSION     DADQDV010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3699)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3699)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3699
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.161"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            5..1087
                     /locus_tag="J8S10_003028"
     CDS             5..1087
                     /locus_tag="J8S10_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017414133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAZ9631552.1"
                     /translation="MNDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTDT
                     RVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINAE
                     FKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKIIS
                     LEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVKN
                     DGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNAVCTKEDG
                     ELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISIT
                     MDTYSHVTDKMRNETVDIMENLRKNS"
     gene            complement(1305..2447)
                     /locus_tag="J8S10_003029"
     CDS             complement(1305..2447)
                     /locus_tag="J8S10_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAZ9631553.1"
                     /translation="MRKIANVYKDRKRGTWFFSATLGQDRFGKRIQVTRRGFKTQGEA
                     RRGLEELKQSFSDSQGIYLQGITFHDFYREYFFPWYKLGTVEKTYMKTDHILQRALDF
                     FGEMQVVKIRPIHIQEFQQFLSKIHVVKKGIEQPLSPNYIKQIFNKLRVVFKRAIVLE
                     IIEENPVDTIGKIKTQRPQVEFWTVDEFKKVYNSVYHGDFYEEFYKRLMRFIFVTGVR
                     SEELLALQWKDFDLINGRCSVNKSIYIRTRQDYEFAETKNTSSIRIISLDRQTVEDLK
                     TWKKTQQSIGKNIELVFSFDGLPPSPRTILSRIKKLAEIAGVKPIHMHGLRHSHVAFL
                     IEHNKNIYAISKRLGHASIKTTLDKYGHLYPETNQALANEITRFDI"
     gene            complement(2452..2637)
                     /locus_tag="J8S10_003030"
     CDS             complement(2452..2637)
                     /locus_tag="J8S10_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAZ9631554.1"
                     /translation="MKTATRKDLINLGFSQYYANKIFKECKELLVEKGYFFYRNSKIK
                     RIPISILEEVLHISWEE"
     gene            complement(2991..3236)
                     /locus_tag="J8S10_003031"
     CDS             complement(2991..3236)
                     /locus_tag="J8S10_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002412373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAZ9631555.1"
                     /translation="MVDKSKKRQYLLVPLSIILSALEGDPISIKMILKHYHSYMAKLC
                     LTNGFNEVGQFVTYVDEYMISQLEIKLIEAILKFKIN"
     gene            complement(3230..3631)
                     /locus_tag="J8S10_003032"
     CDS             complement(3230..3631)
                     /locus_tag="J8S10_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAZ9631556.1"
                     /translation="MQQHYNDISIQHQFDAYCKKVLRNEAKSIRKRNANIKDNEEPLA
                     DSNEGRYSQTHFDEQDVYFLFGMEILISDQKLSAAIDQLSEIRRKIILLYYFAGFNDA
                     EIGKILNMSTSGIWYQRKKAVEQLKMGYDLW"
BASE COUNT         1211 a          672 c          565 g         1251 t
ORIGIN      
        1 agatatcaat gatgatggct caagaaaaaa agtggagaaa gttggcggag acacccgacc
       61 agaggccgaa gctgctttac gaaaagtttt atcagatatt gacgaaacag gacaatactt
      121 tttaggtacg gatactcgag taaaacaata ccttgatttt tggatggagg aatacgttaa
      181 actaaatcta aaatacaata cctatgaaaa ctaccgattt accatcaaaa atcatataaa
      241 cggttattta ggaaagaaaa aacttacgga tctctcccct gctcttttac aaaatttcat
      301 caatgctgaa tttaaaaagg gttactcgaa gaaaacaatg actattactc actctgtcct
      361 taagaatgcg ctgaatatgg cggtttatcc ttggggatta atcaagcaaa atcctatgct
      421 gtatgtaaaa ataccaaaat atgaagcacg accaacgact aaaaaagatc taaaaatcat
      481 ttctcttgag gactttgatc atatgctaga aattactcct gaaggacatc ctttctatat
      541 tcctttgaat attggatttt atacgggaat gcgcgttggc gaagtttgtg gtctgacgtg
      601 ggatgatgtc gatttttcaa atggaacaat tactgtagag aaacaaatgg taaagaatga
      661 cggcgcatgg gtatatggta cgccaaagac aagcagttcc aatcgaacga tttttattgg
      721 acaaaccttg ctagcaattc tgaaaaaaca taagaaacaa caattagaaa atcgaatgaa
      781 gtatggaaag ctctacattg attcaaatgc agtatgtacg aaggaagacg gtgagctagt
      841 tacgccaagt gtagtgaaat ggaatactag gaggatatcg aatgcactct ccctctcttt
      901 taacttccat tctctcagac atactcatgc tacacttctt ctcgaaaatg gcgcaaaaat
      961 gaaagaaatc tctgaacgat tgggccacag cagaatttca attacgatgg atacttactc
     1021 gcatgtaaca gataagatga gaaatgaaac ggtcgatatc atggaaaatc ttagaaagaa
     1081 ttcttgattt ttgccaccga aaaaaaccac cggtggcaaa ccggtggcaa atccatgtaa
     1141 acatggttta ttttttacac tgttttcaaa caaacccttg ctatttcttc ggttcgtcct
     1201 cgtccatttt cgataccgac agctagctta taacccaagg tatatcaaca taaaaaaata
     1261 aaaataggct atgacagcag cgtgacagca aaaaagatgg aaagttaaat atcaaacctc
     1321 gtaatttcat ttgcgagtgc ttgatttgtt tctggatata agtgtccata tttgtccaaa
     1381 gtagttttaa tagaggcatg acctagacgc ttagatattg catagatatt tttattatgt
     1441 tcaattaaaa aggcaacatg cgagtgtctt aatccatgca tatgaattgg ttttactcct
     1501 gcaatttcag ctagtttttt tattctgctt aaaatagttc ttggagatgg cggtaatcca
     1561 tcaaaagaaa aaaccaattc tatatttttc ccaattgatt gttgagtttt tttccatgtt
     1621 tttaaatctt caacggtttg tctgtctaac gaaattatcc gaatacttga tgtatttttt
     1681 gtttcagcaa attcataatc ttgtcttgta cggatgtaaa ttgacttatt tacgctacat
     1741 ctgccattta ttaagtcaaa gtctttccat tgtaacgcta agagctcctc actccttaca
     1801 cctgtaacaa aaataaaacg catcaaacgt ttataaaatt cttcataaaa atccccgtga
     1861 taaacactat tatatacttt cttaaattca tcaactgtcc aaaattctac ttgaggacgc
     1921 tgagttttta ttttacctat agtatctaca ggattttctt caataatttc aagtacaatt
     1981 gcccttttaa aaactactct caacttattg aatatctgtt taatataatt tggtgataat
     2041 ggttgctcaa tgcccttttt tacaacatgg attttcgata aaaactgttg aaattcctgt
     2101 atatgaattg gtcgaatctt tacaacctgc atttctccaa aaaaatccaa tgcacgttgt
     2161 aaaatatgat ctgttttcat atatgttttt tctacagttc ccaacttata ccaaggaaaa
     2221 aaatactctc gataaaaatc atgaaacgtt attccttgca gataaattcc ttgtgaatca
     2281 gaaaaacttt gttttaactc ttcgagtccc cttctagctt ctccttgagt tttgaagcct
     2341 cttctggtca cttgaattct ttttccaaag cgatcttgtc ctaaagttgc agaaaaaaac
     2401 caagtgcctc tttttctgtc tttataaaca ttcgcaattt tcctcatttt actattcctc
     2461 ccaagaaata tggagaactt cttctaaaat tgaaatagga attcttttta tttttgaatt
     2521 acgataaaaa aagtatcctt tctcaactaa aagttcttta cattccttga agattttatt
     2581 agcatagtac tgagaaaaac ctagattaat caaatctttt cgagtagctg ttttcattat
     2641 agcaccttcc ttactttttt tcatttattt ctatcagctg cttttgtcaa aagcacatag
     2701 gaatttcacc tctccccaag tttacggcga gccttacgga agtatcatta tcccaacttt
     2761 aaatcatcgc tttttattga ctataaaaat tattttagaa tatttatcgc tccttcttta
     2821 cagcaagaaa tcatggcgca actaaaatat gctccttaaa gtgttaacgt actgatagaa
     2881 tctatttaat tttcaatgaa caataggttt tctacctaaa agaatctact aattccttaa
     2941 ctattagaag attcttttaa acagaaaaag tggaaagggg atttttttaa ttagttaatt
     3001 ttaaatttta agatcgcttc tattaattta atttctagct gacttatcat atattcatct
     3061 acataggtaa cgaattgacc tacctcgtta aatccatttg tcaaacataa cttagccata
     3121 taagaatgat aatgtttgag tatcatcttg atcgaaattg gatctccttc tagagcagat
     3181 aagataatgg atagtggaac taataggtac tgccgctttt tagatttatc taccataggt
     3241 cataccccat tttcaattgt tcaactgcct tctttcgttg ataccagata ccacttgtgc
     3301 tcatattgag aattttaccg atttcagcat cattaaaacc tgcaaaataa taaagtagga
     3361 taatctttct tcttatctcc gataactgat caattgctgc tgataacttt tgatctgaaa
     3421 ttaatatttc cattccaaat aagaaataga catcttgttc atcaaaatga gtttgggaat
     3481 acctgccttc atttgaatct gccaatggtt cctcattatc ctttatgtta gcgtttcgtt
     3541 ttcgaataga cttagcttcg tttcgtaata cttttttaca gtaggcatca aattggtgtt
     3601 gtatagatat gtcattgtaa tgttgttgca tgataatatg ctcctttttc cccctttcca
     3661 ctaatacaac aatcagaaag cccctttttt tcgaaaaaa
//
LOCUS       DADQDV010000155         3594 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.162, whole genome shotgun sequence.
ACCESSION   DADQDV010000155 DADQDV010000000
VERSION     DADQDV010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3594)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3594)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3594
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.162"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(459..1088)
                     /gene="udk"
                     /locus_tag="J8S10_003033"
     CDS             complement(459..1088)
                     /gene="udk"
                     /locus_tag="J8S10_003033"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HAZ9631557.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1172..1867)
                     /locus_tag="J8S10_003034"
     CDS             complement(1172..1867)
                     /locus_tag="J8S10_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="noncanonical pyrimidine nucleotidase, YjjG
                     family"
                     /protein_id="HAZ9631558.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1880..2596)
                     /locus_tag="J8S10_003035"
     CDS             complement(1880..2596)
                     /locus_tag="J8S10_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HAZ9631559.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2926..3531
                     /locus_tag="J8S10_003036"
     CDS             2926..3531
                     /locus_tag="J8S10_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HAZ9631560.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEESTGEGGEPEVIGSTEE"
BASE COUNT         1025 a          741 c          649 g         1179 t
ORIGIN      
        1 ggggtgcgac aaaagagctt cttcaaaaaa ataagtcgaa atctcacaca aattcgagaa
       61 ataattttcg taagtttctt cttatttatt gcatctgacc acttctgtta caacctctcg
      121 ttaaacggtg ttcaaaagct tgcatctacg ataataagcc caacccaacg aaaaacgtga
      181 ggagctgttt tatttggatg ctcttatcgc ttgatgcaaa gacagctttt ttacaacctc
      241 tacttcacgg tgctcaatca gctgaccttc ggtattagct caaaaaacgg taaaatataa
      301 acagctattt tccgtttctt ctttttaata cttaggtcaa gatgctgttt tcacaacctc
      361 ttgttataaa taaaaaaaac agttggctgg tgactgttca aaaagcagaa tccttgcttt
      421 tcaaacggtc gcagtccgtt caactgtttc gctgcgcact atttatggtt taagaaacta
      481 gctacttttg ttgtaatcaa atcaatagca acgtggtttt ctccgccttc tggaacaatg
      541 atatccgcat agcgcttcgt tggttcgata aattgatgat acatcggttt aacaactgtc
      601 aaatattgtt cgatcacgga gtccaatgtg cgtccccgtt cttccatatc ccgtttgata
      661 cgacgaatga tacgaatgtc atcatctgta tctacgtata ctttgatatc catcaagtca
      721 cgcagacgtt cgtcttctaa aatcaggatt ccttctagaa tgatcacttc ttttggttcc
      781 tgaatgatcg ttgcctgact tcttgtatgc gctacatagt catacacggg tttttcaatg
      841 gctttatagt tcagtaagtc gcctacatgc tgaatcagca gatcattatc aaaggcaaat
      901 gggtgatcgt aatttgtgtt caatcgttct tcaaaactca aatggctctg atccttgtaa
      961 taagaatctt gttcaagcat catgatggaa tggtccggga agttgttgaa aatcgcacgg
     1021 ctgacacttg tctttccgct tccggatcca cccgtcacac caatgataat tggcttgctt
     1081 tttgtcattg actaaaacct ctttcgtatc cgttttttca ttctaatcta ttatagcgaa
     1141 aaaacacgaa aatgctatat ttttctgaaa attaatcctt ttcaatttcc aataatgaat
     1201 aaagttcctc taatgaatcg attcgataag taggctggat ttcttcgatt tctggtaatt
     1261 tatttctatt gaaccaaatc gtatcgatcc ctgccatatt tcctcctttg atatcagaag
     1321 tcaaagaatc accaatgatc acagtttgct ttttatcaaa attaggaatg tgggaaaaga
     1381 catgatcaaa aaattctttc atcggctttt gcgctccgac agcttctgag acaaagatat
     1441 ccttgaagta atcaagcatt cctgcatctg ttaatcgccg atgttgcgtg tgcgacacac
     1501 cgttcgtcac aatataaaga tcagcatgcg gatggacctt tttcaggatt tctagacttc
     1561 ctggaacaag atcatgacct tggttcaagt agtggcggta gcgtttttcc atttgatcac
     1621 tatctactgt tttcccaaat tgctggaaaa gtaacccaaa acgactgcct attatttctt
     1681 ctcgtgatag tctgcctttt tcaaactcct gccataaatg atgattcaaa gccttatagc
     1741 tggtttcgat ttctggtgtc aatgtgattc cttgttctgc aaacaaagca cttaaagcat
     1801 tggcttcagt taattgaaaa tctaacaatg tatcatctac atcgaacaat aaagttttat
     1861 atttcatctt tttgacctcc tatttaaaat aaatacttaa ctttttcatc tctgctaatg
     1921 tcaacgatcg atactcgcct actcctagct gttcatctaa ttccaatggt cccatgctta
     1981 gccgtttcaa tgcggtcact ttctttcctt gggctaagaa catctttttg acttgatgga
     2041 attttccttc ttggatcgtc aataaaaccg tactttggtg cttgtctgct ttgagtattt
     2101 ttaaatcagc cggcttacat tgatacccat cagcgaatac gattccattt tcaaatgctg
     2161 ttacgtctgc cggtgtcacc ctttcgttca caactacttg ataagtcttt gaaacctttt
     2221 tttctggaag tagcatttca tatcccaatt gtccattcga agtgatcagc aatagtcctg
     2281 ttgtatctct atctagtctt cccactggat ataatggttg gaaacgatcg gcacttgcaa
     2341 tcagatcgat tactgtcgtc ttttctggat ctgatacagc tgtaacagct ttttcaggtt
     2401 tattgagaag ataataggac tcatttgttt ctaagtgttc acctgctact tcgatttgat
     2461 gcagtaaact atctacattt cgattttgtc gaaattcgac tgtgccatct atcatcactt
     2521 gcttcaaagc aaacagccgc ttcatttcct tgcgtgtcgt ttctaatttt tcttctatta
     2581 atttatctaa acgcatgctg tttcctttct tattactact aattaattat accttgaata
     2641 ttcttgcttg caaatacatc atcatagtta ttccttgact taattaacag ttcacgttac
     2701 ggttaaatag taaagtgaat tggatttctc atacacagcg taatgacctg gtggagaaaa
     2761 gttgaatcct gactttctaa ggggagatgc gcgcatctct ccttttgcgc ttttttaagc
     2821 gccctgcctt cgatgatgtg cacgagatta gcctttagaa ttcacttaaa taaaatctgt
     2881 ccgttaccaa agcagacagt cacattttaa ggaggaattt tggttatgtc agtatcatta
     2941 gaagtaagta aaagagaagt acgtccccgt tcattaagaa acaaacttcg tcacgaaggg
     3001 aaagttccag ctgttgttta tgggtataaa gtagaaagta cccctatctc attcgatggt
     3061 ttgacactaa gcaaattgtt gcgtgaacat ggagcgaaca cagtcatcac gatggacatc
     3121 gatggacaaa aagtcaatac attggttcac aagatccaaa cgaacacttt taccaatcat
     3181 ttcgaacatg cagaatttct atctgtaaac atgtcggaag aaacagaagt cgaaacagaa
     3241 gtcgttcttg ttggcgaatc agtgggtgct aaatctggtg gagtgttagc tcaaaacttg
     3301 tatacagtag tcgtatctgc tacaccagac aaattgcctg aacgaattga agttgacgtg
     3361 acaaacttgg aattaggtga ttctattaca gtagccgatc ttccaaaaaa cgacgattac
     3421 aaattcgtga ccgacagtga agagcaaatc gctgctgtag tcgctcaaag tgaagaagaa
     3481 agcacaggtg aaggtggcga accagaagtg atcggttcaa cagaagaata atactgaaac
     3541 aatcaggtgg tgttagaagc ggcgggtcag cagcttttaa cacgcctttt ttat
//
LOCUS       DADQDV010000156         3418 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.163, whole genome shotgun sequence.
ACCESSION   DADQDV010000156 DADQDV010000000
VERSION     DADQDV010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3418
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.163"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            288..554
                     /locus_tag="J8S10_003037"
     CDS             288..554
                     /locus_tag="J8S10_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631561.1"
                     /translation="MAKITKNEQENLVENYTKKPAYSNSRLDAHFVCTSNPKLSFDAM
                     TIVGNLNKNSAKKLSDFMSLDPQIRLWDILQTKFKAKALQDPLC"
     gene            612..1124
                     /locus_tag="J8S10_003038"
     CDS             612..1124
                     /locus_tag="J8S10_003038"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003321317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAZ9631562.1"
                     /translation="MTNKNNERYSTELKATAIKKMMPPENRGIRQLSQTLGIPEATLY
                     SWRKKARIQGNTTPGTKKNVEKWSSEDKFLIVMESFSMNQVELAEYCRKKGLFKEQIE
                     AWKKTCLSANEQEENRTRELATELKEEKKQARQLEKELRHKEKALAEAAALLLLRKKA
                     HAIWGDQEEE"
     gene            1121..2158
                     /locus_tag="J8S10_003039"
     CDS             1121..2158
                     /locus_tag="J8S10_003039"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAZ9631563.1"
                     /translation="MISSSDRKQAVELIQEANRNGARLTYACNELNISVRTYERWTRE
                     GTIAHDQRPLAKRPVPKNKLTDQEREKIIETVSKKEFMNLPPSQIVPKLADCSIYIAS
                     ESSFYRVLREKNMQHHRGRSQVSQKRIPPSHLATKPNEVWTWDITWLKGPIKGLFYRL
                     YLIIDLFSRKMVGWEIWESEEARHAEKLIKQTVLKERIQGQPLVLHSDNGSPMKAATF
                     QVLLEKLGIQSSYSRPRVSNDNPYSEAAFRTLKYRPEYPNNGFKTIDDARKWTKEFVD
                     WYNDSHLHSGIQFVSPAACHEGRHLAILEKRKQVYEDAKKRHPERWSKGVRNWTPHQS
                     VALNPLKETES"
     gene            2318..2494
                     /locus_tag="J8S10_003040"
                     /pseudo
     CDS             2318..2494
                     /locus_tag="J8S10_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
     gene            2549..3418
                     /locus_tag="J8S10_003041"
                     /pseudo
     CDS             2549..3418
                     /locus_tag="J8S10_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012655884.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
BASE COUNT         1288 a          543 c          652 g          935 t
ORIGIN      
        1 ataaattatc taaagagaat taagttttga ttatgtaata agttttggta ctaaaaaaga
       61 cttgatctaa ttagaccaag tcttttgtta gtgttatatt aataacaaaa taaaaataag
      121 aagtcgctca ctccccgacc aaagtttgtg agcaaaataa acagtcgatg tttgtttctt
      181 aattgtatat cttgatatta aacgatttaa gattattctt caagatatat attcgcaaat
      241 gtaattggaa aagcgacttc ttaaacaaaa ttaaggagtc gctttttatg gcaaaaataa
      301 cgaaaaatga gcaagaaaat ttggtggaaa attacacaaa aaaaccggcg tactctaata
      361 gccggttaga cgcacatttc gtgtgcactt ctaatccgaa attgagcttt gacgctatga
      421 cgatagtcgg aaaccttaat aaaaacagcg ctaaaaagct atccgatttt atgagtttag
      481 atccacaaat tagactttgg gatatacttc aaacaaaatt taaagctaaa gcactacaag
      541 accccctatg ttaggctagt tgtcgtatag gataataagt tataataaag actatacgga
      601 ggatgattac catgacaaat aaaaacaatg aacgttactc taccgaactg aaagcgacag
      661 ccatcaagaa aatgatgcca cccgaaaata gggggattcg ccaattaagt caaactttgg
      721 gcattccaga agcgactctt tattcttggc gtaaaaaagc tagaattcaa gggaatacta
      781 cacccggaac gaaaaaaaat gtcgaaaaat ggtcaagtga agataaattt ttaattgtga
      841 tggaatcatt ctcaatgaac caagtagaac ttgcggaata ttgccgaaag aagggcttat
      901 ttaaagaaca aattgaggct tggaagaaaa cgtgcttatc tgcgaatgaa caggaagaaa
      961 atcgaacgag agaacttgca actgaactaa aagaagagaa aaaacaagcg cgtcaattag
     1021 agaaagaatt acgtcataag gaaaaagcat tagcggaagc cgctgctctc ttattactaa
     1081 gaaaaaaagc acacgcgatt tggggggacc aagaggaaga atgatttcat cttcagatcg
     1141 caaacaagct gttgaactta ttcaagaagc caatcgcaat ggggcccgtc tcacctatgc
     1201 ctgtaatgag ctgaatatta gcgttcgaac ctacgaacga tggacgcgtg aaggtacgat
     1261 agcgcatgat caacgccctt tggcgaaacg tcctgtaccc aaaaataaac tgacggatca
     1321 agaacgcgaa aaaataatag aaaccgtttc aaaaaaagaa tttatgaatt tgccacctag
     1381 ccaaattgta ccaaaacttg cggattgctc gatttatatt gcatcagagt ctagcttcta
     1441 tcgtgtattg cgagaaaaaa atatgcaaca tcaccgtggc cgaagtcaag tttcacaaaa
     1501 acgcataccg ccaagtcacc ttgcgacgaa gccaaatgaa gtttggactt gggatattac
     1561 ttggctaaaa ggtccaataa aaggactctt ttaccggtta tatctcatca ttgatttatt
     1621 tagccgtaaa atggtaggct gggagatttg ggaatcagaa gaagctcgtc atgccgaaaa
     1681 acttattaaa cagacggtgc ttaaggaacg tatccaagga cagccgttgg ttttacactc
     1741 cgataatggc agccctatga aagccgcgac ttttcaagtc ttactcgaaa aattaggaat
     1801 tcaaagttct tattcaagac cacgagtgag taatgacaat ccttattcgg aagcggcttt
     1861 ccgaacgtta aaatatcgac cagaatatcc caataacggc tttaaaacaa tagatgatgc
     1921 tcgaaaatgg acgaaagagt ttgtcgattg gtataacgat tctcatttgc atagtgggat
     1981 tcaatttgtg tctcctgcag cgtgtcatga aggacgacat ctcgctattt tagagaaacg
     2041 aaagcaggtt tacgaggacg ctaaaaagcg ccatcctgaa cgctggtcaa aaggtgttcg
     2101 aaattggact ccacatcaat cggtggcgtt gaatccttta aaagaaacag aaagttaaca
     2161 ggagcataat ctttcaagat tatcaaataa ccctcgtcac ccaatagggg aaaaagttat
     2221 tcttccccta ttggataacg aggccaaccg accataggga ggttctgctt tttgataggt
     2281 ggaaaataaa aatacgacaa ctatattgac aaacaccgac catcgtccag taaagagacg
     2341 caataaattc tatcgaagtt tacgcactgc ctctacaacg attaaaggca tggaagccat
     2401 ccgaggatta tataagaaaa cccgaaaaga aggcactctc ttcgggtttt cggtctgtac
     2461 tgaaatcaag gtattattgg gaatcccagc ttaaatcata gataccgtaa gggattttat
     2521 tctttattta aaactttgca acagaaccga atcattaaaa aaacattata cagagccttg
     2581 ggaagatgaa gtttttagag taattattga atataacaat gttcctattg gatatggaca
     2641 aatatataaa atgtatgatg agttatatac tgattatcat tatccaaaaa ctgatgagat
     2701 agtctatggt atggatcaat ttataggaga gccaaattat tggagtaaag gaattggtac
     2761 aagatatatt aaattgattt ttgaattttt gaaaaaagaa agaaatgcta atgcagttat
     2821 tttagaccct cataaaaata atccaagagc aataagggca taccaaaaat ctggttttag
     2881 aattattgaa gatttgccag aacatgaatt acacgagggc aaaaaagaag attgttattt
     2941 aatggaatat agatatgatg ataatgccac aaatgttaag gcaatgaaat atttaattga
     3001 gcattacttt gataatttca aagtagatag tattgaaata atcggtagtg gttatgatag
     3061 tgtggcatat ttagttaata atgaatacat ttttaaaaca aaatttagta ctaataagaa
     3121 aaaaggttat gcaaaagaaa aagcaatata taatttttta aatacaaatt tagaaactaa
     3181 tgtaaaaatt cctaatattg aatattcgta tattagtgat gaattatcta tactaggtta
     3241 taaagaaatt aaaggaactt ttttaacacc agaaatttat tctactatgt cagaagaaga
     3301 acaaaatttg ttaaaacgag atattgccag ttttttaaga caaatgcacg gtttagatta
     3361 tacagatatt agtgaatgta ctattgataa taaacaaaat gtattagaag agtatata
//
LOCUS       DADQDV010000157         3219 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.164, whole genome shotgun sequence.
ACCESSION   DADQDV010000157 DADQDV010000000
VERSION     DADQDV010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3219
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.164"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            136..951
                     /locus_tag="J8S10_003042"
     CDS             136..951
                     /locus_tag="J8S10_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631564.1"
                     /translation="MVKIAGLSKGGKTVSQLYKQNYRDWRQFRKNIKDSYFILPTELE
                     KYLPNNKAINLYLYYCFKAKNEGGDSWHSVNTIAESLGVTTKTINTWNKTLVDLGMIA
                     RIDDNHLSKSTILLPLSSYYKLALDSSLKDVTESTVHEIDGNLVAVYHLFEWRKNEAD
                     ENYNVPYNTLCCVFKRKTQKDTIYKFILVQDEKISNFELSTPSSKIYDDAYRFECQDL
                     EALLSANNLNNIEHENFVVNTRFNLVSEKDSDLLDLLIELTKNLDKKENITVL"
     gene            1077..1334
                     /locus_tag="J8S10_003043"
     CDS             1077..1334
                     /locus_tag="J8S10_003043"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631565.1"
                     /translation="MANLYIENKGDLNAIITLIVVMVKSIGNITIGMLFIILAAVLIF
                     MIVIWFLNERSKDNQHRRDMEIKSIESIDYLSIITLKKPRS"
     gene            complement(1586..2158)
                     /locus_tag="J8S10_003044"
     CDS             complement(1586..2158)
                     /locus_tag="J8S10_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAZ9631566.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(2174..2779)
                     /locus_tag="J8S10_003045"
     CDS             complement(2174..2779)
                     /locus_tag="J8S10_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell filamentation protein"
                     /protein_id="HAZ9631567.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
BASE COUNT         1055 a          585 c          490 g         1089 t
ORIGIN      
        1 agtgactaga gaattaaata aaaaataatt actatctagt acgaaattaa ttacatagga
       61 taatatatta aggtgctgga ctacaagtaa aaaatactgt atgatcatga cagattcaag
      121 aaaggagcaa taagattggt taagatagca ggactttcta aaggtggaaa aaccgtttca
      181 caactttata aacaaaacta cagagactgg agacagttca gaaaaaacat taaggattct
      241 tactttattc taccaacaga acttgaaaaa tatttaccga ataacaaagc tattaattta
      301 tatctgtatt actgttttaa ggcaaagaat gaaggcgggg attcctggca ttcggtcaat
      361 accatagcag agtctctagg agtgacaact aaaactataa acacctggaa taaaacctta
      421 gttgatttag gtatgattgc acgtatagac gataaccatc tcagtaaatc gacaatttta
      481 cttcctctct ctagttacta taaattagcc cttgatagtt ctttaaagga tgttaccgag
      541 agcactgtcc atgaaattga tggcaacttg gttgcagttt atcatttgtt tgaatggaga
      601 aaaaatgagg ctgatgaaaa ttataacgtt ccttataaca cactctgttg tgtttttaaa
      661 agaaaaacac aaaaagatac tatctataaa tttatcttgg tccaagatga gaaaataagt
      721 aatttcgaat taagcactcc ttctagtaag atttatgacg atgcatatag atttgaatgt
      781 caagatctag aagccctcct ttccgcaaat aatctaaaca atatagaaca tgaaaacttt
      841 gttgtaaaca ctagatttaa tttagtttct gaaaaggact cagatttgtt agatttgctg
      901 atagagctta ctaaaaatct agataagaaa gaaaacatta ctgtactata actagcatcg
      961 gtccatcatt aagtttggac tattagaaca cttgctatta cagaaaaagg tatgctagcc
     1021 acgcttacta tttattggta tcaaacaagt atcttaattt gaaaggaaga tgatttatgg
     1081 ctaatttata tatagagaac aaaggagact tgaatgccat tattacttta atcgtagtta
     1141 tggtaaaatc aataggtaat atcacaatag gaatgctgtt tattatatta gcagcagtgc
     1201 tgatttttat gatagttatt tggttcttaa atgaaagatc taaagacaat caacaccgta
     1261 gggatatgga gataaaatca atagagtcaa tagattattt atcgataata acactaaaaa
     1321 agccacgttc ctaaacgtga cttacgctga acgatatgtg ttgtttggta gacgaacaaa
     1381 tcgttcatta taaatatatg atggtatcct aatatagtaa gcgtggctag cataccttta
     1441 attactttac cttttacagt taccatacac attttttgag cagaaatcaa gtaaataaaa
     1501 aaatattata tttcacaaca tgctaataga ctcatatcta gaacgcatta agtatttacc
     1561 tgtctggttc gctgagactt cttttttaac tttcttcaat tttcttcttt attctaaaaa
     1621 gcgtactgcg actgaaaccg gttatagctt caacttcctt atacgattta cctgaagtaa
     1681 gcagttcata tgcgtgcctc ttcttcggtg tgattgttgc tttcggacgt ccttctctga
     1741 aattaggatt attctttctt gcaaacattt ttccttcttg ggtacgttcc acaatcatat
     1801 cacgttccat ttctgctaca ctcaacaacg tccgtgtcac cattcgcccc atggacgtat
     1861 tttcaatcgt tcctagattc aaaaccttga tcgttacgtt atcatcgagt aaaggttcaa
     1921 tgatctctaa tgcttctctc gtgttacgag caaatcgatc aagcttcgta acaactattt
     1981 catctccagg cttcagacca gccaacagct gattgaattt tggccgatcc cgttttgtac
     2041 ccgtaaattt ttctgaaaaa atattcttct tctctacgcc gttctcaagc aactgttgaa
     2101 tttgttcttt tgtactttga gaagcggttg agacacgtgc atatccatat ttcgtcattt
     2161 ggtccaccta cttttacaaa tcatctatcg tatactcaga atacccttca tagaaatagc
     2221 tgacatcgat tcctttcata tataactcgc gatcgtcaat tttatcagtc agagcattgg
     2281 aaattagata gcgtatttcc aaatcgttta tgggacttcg ctccattgca gaaagatagt
     2341 ctgctttatc gattaagttc caatctacaa ctttttgcaa ttcttccttt aaaatgagat
     2401 ccagccaaat tctagtactt cggccatttc cttctcgaaa tgggtgagcg atattcatct
     2461 ccacatattt cttgataatc tcttcaaaag aagtttgtgg catctgatca atatgctgta
     2521 acgaatgttc taaatacata actggtgcaa atcgaaaatt tccttttgca atattgaccg
     2581 atcggatttt tccggcaaaa tcgtaaatat ccgaaaatag aaattcatga atttcagata
     2641 aacctttaaa tgtaccaact tcgatttcat ttatttttcc acaatcgtac aattctttcg
     2701 ctttttgttt actgagtttt tcttcaacct tagccaactc aacttgattg gttaatccca
     2761 atttattctc taaaatcatg cgaaatctcc ttaactttat gacataagtt tatgaaacac
     2821 tctcaacccc attatatcgc gattttgttt atgtgtcaaa aactattaag tttctgaccc
     2881 ccgatagatt tttcaagtgt ctctattttg cacagtctag ttgacctttg atacacctct
     2941 atatttatag agaatctaaa acatcaacat ggcatactca aaattctaaa tattagggat
     3001 aaagaattct cctatacaat caaaaatttc ctttatttcg aactccggtc acctaactct
     3061 attgatctct tacaagccaa agaatatctc tatactacaa agaaacaata gggtgcctgg
     3121 ttggtctctt tgtgttttat tttagaatct agaacgtaaa tattcttgtc attctgattt
     3181 tatctaagaa tatcaattaa atcttttttt gcagcctct
//
LOCUS       DADQDV010000158         3219 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.165, whole genome shotgun sequence.
ACCESSION   DADQDV010000158 DADQDV010000000
VERSION     DADQDV010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3219
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.165"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            50..1438
                     /locus_tag="J8S10_003046"
     CDS             50..1438
                     /locus_tag="J8S10_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-directed DNA polymerase"
                     /protein_id="HAZ9631568.1"
                     /translation="MYKERDDLNYTLIINKDGNYSWRPLVLLHPILYVDLVNCLTKED
                     HWEELKKRFSEFKKDKNINCYSIPVEASKGSKRTDLGETILNWWEYFEQKSLAQNIKY
                     QYCMFTDIADCYPSIYTHSITWAMYGKEKVKNDENKCSGSLGDKIDKKISGMQHNQTN
                     GIPQGSVLMDFVAEIVLGYVDLRLSKELKKLENLKDYKVLRYRDDYRIFSNNRNDLEQ
                     IMKVLSEVLYDLNFKLNSSKTKLSDDIIIDSIKKDKLYWEEIKASIRMNATNLDGDRE
                     IRYSINLQKHLLEIKKLADKHPNSGQLKKALSEFNKERIIKITSKPNDLLPLIGILVD
                     IMINNPGSLPQCVLIIGQLLNFENESKAREIVEMIINKYALKPNTEFMMIWFQRLTTI
                     FGEMFDSVLSSEFVSKIKDPVSNQMFSVDWLNEDAKKSFYEGTIKDEEKYIKMSKKIY
                     ITEFDDFNDYPF"
     gene            1776..>3219
                     /locus_tag="J8S10_003047"
     CDS             1776..>3219
                     /locus_tag="J8S10_003047"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HAZ9631569.1"
                     /translation="MTEQIEKNSKSLYQALWNSADILRSKMDANEYKSYLLGLVFYKY
                     LSDNMLRYVSVLLEEETDDLNKAQDLYVEAFKDADIKDDLLYELKDEFSYTIAPALTF
                     TAQVAAIHDGSFQLEDLVQGFRDIEQSSENFENLFEDIDLYSKKLGSTPQKQNKTIAD
                     VMKELEGLNMAGHAGDVLGDAYEYLIGQFASESGKKAGEFYTPQPVAKLMTQIVLQGK
                     EDKKGFSVYDATMGSGSLLLNAKKYSHQPGTISYFGQELNTSTYNLARMNMILHGVPI
                     ANQHLHNADTLDQDWPTEEPTNFDGVLMNPPYSAKWSADKGFLDDPRFSAYGVLAPKS
                     KADFAFLLHGYYHLKDTGVMAIVLPHGVLFRGGAEGKIRKALLENGAIDTVIGLPANI
                     FFNTSIPTTVIILKKDRAKKDVLFIDASQDFEKIKTQNTLRDYHIDAILEAYKTRTIK
                     DKYAYVAEFDEIVENDYNLNIPRYVDTFEEE"
BASE COUNT         1183 a          505 c          583 g          948 t
ORIGIN      
        1 ttcaaaaaaa aaccaaccga aagatataaa agatattgta gatacacgaa tgtataaaga
       61 acgtgatgac ttaaactata cgcttattat caataaagat ggaaactatt catggcgtcc
      121 tctcgttcta ctacatccta ttctatatgt agatttggtt aattgtctca ctaaagaaga
      181 ccattgggag gagttaaaaa agaggtttag tgaatttaaa aaagataaaa atattaactg
      241 ttattctata cctgttgaag cttccaaagg ttcaaaaagg acagatcttg gtgaaacaat
      301 actaaactgg tgggaatatt ttgaacaaaa aagcttagct cagaatatta aataccaata
      361 ttgcatgttt actgacatcg ctgattgtta tccatcaatt tatactcact ctataacatg
      421 ggccatgtat ggtaaagaaa aagttaaaaa tgatgaaaat aagtgttcgg gctcacttgg
      481 cgataaaata gataaaaaaa tatctggaat gcaacacaat caaacaaatg gtatccctca
      541 gggttccgtt cttatggatt ttgtagcaga gatcgttcta gggtatgttg atttgagatt
      601 atcgaaagaa ttaaaaaaat tagaaaattt aaaagattac aaagtactca gatatagaga
      661 tgattataga atattttcaa ataatcgtaa tgatttggaa caaattatga aagtgttatc
      721 agaagtctta tatgatttaa attttaagtt aaattctagt aaaacaaaat tatcagatga
      781 tattatcata gattctatca aaaaagataa gctctattgg gaagaaatta aggcaagtat
      841 aagaatgaat gccacaaact tagatggtga tagagaaatt cgttatagta taaatttaca
      901 aaaacattta ttggaaataa aaaagttagc agataagcat cctaattcag gccaattgaa
      961 aaaagcactt tctgagttta ataaagaacg cattattaaa atcacttcaa agccgaacga
     1021 tcttttacca cttattggta tcctggtaga tatcatgata aataacccgg gttctttgcc
     1081 gcagtgtgtc ttaattatag ggcagttatt aaatttcgaa aatgagagta aggctagaga
     1141 aatagttgaa atgattataa acaaatatgc tttaaagcca aatactgaat ttatgatgat
     1201 atggtttcaa agattgacca ccatttttgg agaaatgttt gatagtgttt tatcatccga
     1261 atttgtatct aaaatcaaag atcctgtctc taatcagatg ttttctgtag actggctaaa
     1321 tgaagatgct aagaaatctt tttatgaagg gaccattaaa gacgaagaga aatatattaa
     1381 aatgagtaag aaaatatata ttactgaatt tgatgatttt aatgattatc ctttttaagt
     1441 gaaaatttag aatgaatata aaaaacatta caatctaatt tttttaaaaa aatgttatat
     1501 cggaagtaat ctcttgattt ctatactata agataagaaa accactattt aacaaggtta
     1561 ttcgaacctt attttaagtt acttattatt taatgtatcg aaaaaggtga aataggtttg
     1621 ttataataag aattaagtaa gacatgaatt gtctaagcaa atgtagctta tccatttcat
     1681 taaaatacat atggtgaaaa aacaagttca aatagtaact aattttttaa aaaactgatt
     1741 tataaaaaat acaacacgaa tgaggaaaat aaccaatgac agaacaaatc gaaaaaaatt
     1801 caaaaagctt atatcaggca ctgtggaatt ccgcagatat cctgcgttca aaaatggacg
     1861 ctaatgaata caagagctat ttactaggct tggtctttta taaatactta tccgacaaca
     1921 tgctgcggta tgtctccgtt ctattggagg aagaaacgga cgacctaaat aaagcacaag
     1981 acctttacgt tgaagcattt aaagatgcag atataaagga tgatctcttg tatgaactaa
     2041 aagatgagtt ttcatatacc atcgcacccg cattgacctt taccgcgcaa gtggcagcca
     2101 ttcatgatgg atcttttcaa ttagaagacc tggtacaagg tttccgtgac attgaacaat
     2161 ccagcgaaaa ctttgagaac ttatttgaag acattgatct gtattctaaa aaactggggt
     2221 caaccccaca aaaacaaaat aaaaccatcg cagatgttat gaaagaatta gaagggttaa
     2281 acatggcggg gcatgctggc gatgtcttag gcgatgccta tgagtactta attggccaat
     2341 tcgcatctga atccggtaaa aaagccggtg aattctatac cccacaaccg gtcgcaaaat
     2401 tgatgacaca aattgtttta caaggaaaag aagataaaaa aggcttttct gtttacgacg
     2461 cgaccatggg ttcgggctcg ttacttttga acgctaaaaa atattcccat caaccgggaa
     2521 ccatttctta tttcggacaa gagttgaata cgtctaccta taatttggcg cgtatgaaca
     2581 tgattttgca tggggttccc attgccaacc aacacttgca taatgcggat accttggatc
     2641 aagactggcc aacagaagag ccaacgaact tcgatggggt gctcatgaac ccaccgtatt
     2701 ctgcaaaatg gtcggctgat aaaggcttct tagatgaccc acgcttctct gcctatggcg
     2761 tattagcccc taaatcaaaa gcggactttg ctttcttatt acatggctac tatcatttga
     2821 aagatacggg cgtcatggcc attgttttgc cacatggggt gctctttaga gggggcgcag
     2881 aagggaagat acgcaaagcc ttgttagaaa atggtgccat tgacaccgtc attggcttac
     2941 ctgctaacat cttctttaat acgtccattc caacgaccgt aattatcttg aagaaagacc
     3001 gtgcgaaaaa agatgtgctc tttattgatg cgtcacaaga ttttgaaaaa ataaaaacgc
     3061 aaaatacgct acgagattac catattgacg ctattttaga ggcctataaa acccgtacaa
     3121 ttaaagacaa gtatgcttat gtcgcagaat ttgatgaaat tgtggagaat gattacaact
     3181 taaacattcc ccgttacgtg gatacctttg aagaagaag
//
LOCUS       DADQDV010000159         3064 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.166, whole genome shotgun sequence.
ACCESSION   DADQDV010000159 DADQDV010000000
VERSION     DADQDV010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3064)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3064)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3064
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.166"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            581..1540
                     /locus_tag="J8S10_003048"
     CDS             581..1540
                     /locus_tag="J8S10_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAZ9631570.1"
                     /translation="MTYTHLTPTELVMIEAYFNQSHSVSKVAHLVQRSRQTIYNVYRF
                     LKSGGSAISYYEQYKKNKRNCGRRPIVLPDGQQEYIQKKVAQGWTPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDPHDLPMKGKRKPNGHKEKRGKQAFRRSIQDRTTDYIQFNHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPAGRQAIDIENRLNQWFQSVPKHLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNK
                     VSETFIQSVASKRNHIPRKSLHYRTPLEVFLSYVGKDDLSSLI"
     gene            complement(1527..2132)
                     /locus_tag="J8S10_003049"
     CDS             complement(1527..2132)
                     /locus_tag="J8S10_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631571.1"
                     /translation="MINSAYFHIKYLKKYEYEEVVLDYGLNRQSFLIYAINNGNLPSN
                     KKNIIIETYAYLEGGSKKLIKSCNIEYQLSVGEIKCVFEEDLELDLKKIFASIHDYIG
                     LIYKIIEDDKQTELNMCYFDREQDFFYYGGMGGGSIVPKINLVELDVNNYRELYVFNS
                     LDFEIPMKQMKNIDIHILPSESCQIEYSIEYFYKVSFVKLS"
     gene            complement(2372..>3064)
                     /gene="tnpB"
                     /locus_tag="J8S10_003050"
     CDS             complement(2372..>3064)
                     /gene="tnpB"
                     /locus_tag="J8S10_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family element transposase accessory
                     protein TnpB"
                     /protein_id="HAZ9631572.1"
                     /translation="ATISRHSSGKYYISLLCKEEVRELPKSNSAVGIDLGIIDFAILS
                     TGQKFDNNKFTSKMEKKLKREQRKLSRRALLAKQKGINLFEARNYQTQKRKVARLHEK
                     VMNQRTDFLNKLSTEIIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSSFVSKLQYK
                     ADWYGRKIIKVDKWFPSSQICSNCGHKDGKKSLEIRKWTCPICHTHHDRDINASINIL
                     TEGLRLHSMGLA"
BASE COUNT          998 a          509 c          478 g         1079 t
ORIGIN      
        1 aacaataaat gaagactttt ttattgttaa ttgtttattt ttctattatt agatatgaaa
       61 atcgcattta gataaaatag aaaaatatga atatatttta aatattaaga tgagagtcat
      121 taacttatga tagtagtcaa tttgcttttc actaattaca aaatatgtga tataggaagt
      181 ttagttattg ttctcataat gccatcctgt ttttagatta tctagtaatt tttttgttat
      241 ttaaaattag gagcagtgcc aattgtttta attttaaagg ctttttttat atcttctaaa
      301 ttagaagata tttgtatatc aatatggaat atattacctt ttttgtattt ttttatgtta
      361 tctttagcta aaacatcaaa tacatgtcct tgaaattgta tcgaggcagc tggatttagt
      421 ttaaattgag gaaactttac cacagctgat tcaaaacact tgtcacattt ttttattttt
      481 ttaccttcgc cgattgtaaa attaagctag acaactaaaa aagtcatttg tgctacactc
      541 aaaatagttc cgtcgaaaga attataagga gtgagtacaa atgacctata cccatcttac
      601 accaactgaa ctcgtaatga tagaagctta tttcaatcaa tcacactctg tttcaaaagt
      661 agcccatctg gtacaacgtt ctcgacaaac catttataat gtctatcgtt ttcttaaatc
      721 tggtggaagc gcaataagct actatgaaca atataagaaa aacaaacgta actgcggaag
      781 acgtccgatt gtgttaccag atgggcaaca agaatacatt caaaaaaagg tggctcaagg
      841 gtggactcca gatgtcctta ttggtcgagc agagtttcct attgcttgtt cggtacgtac
      901 actatatcgg atgtttaaag ataaaacctt tgaccctcac gatttaccaa tgaaagggaa
      961 aagaaaacca aacggacata aagaaaaaag aggaaaacaa gcttttcgcc gttcgattca
     1021 ggatagaaca actgattata tacagttcaa tcatgagttt ggtcacctag aaggtgacac
     1081 cattgtcggt ggaaaacata aaagtgcggt gatcacgtta gttgagcgat tatctaaagt
     1141 gatcatcacc ttgaaacccg ctggtaggca agctatagat attgagaata gactgaatca
     1201 atggtttcaa tctgtaccga aacacttgtt taaatccatc acatttgatt gtggaaaaga
     1261 gttctcgaat tggaaaaaga ttagtaatac caatgatatt tcgatttatt tcgctgatcc
     1321 aggaacacct tctcaacgag gactaaatga acattcgaat ggcttattac gtaaagatgg
     1381 cttatataaa gctatggatt ttaataaggt atccgaaacc tttatccaat cggtggcatc
     1441 aaaacgaaat catattccta gaaaatcatt acactatcgc acaccattgg aagtattttt
     1501 gagttacgta ggtaaagatg atttgtctag cttaatttga caaacgaaac tttgtaaaaa
     1561 tattcgattg aatattctat ttggcacgac tcacttggca gtatatgtat gtcaatattt
     1621 ttcatctgtt tcataggtat ttcaaaatct aaactattaa aaacatataa ttccctgtaa
     1681 ttatttacat ctaactctac taaatttatc tttggaacaa tagatcctcc acccattcca
     1741 ccataataaa aaaaatcttg ttctctatca aaatagcaca tattaagctc agtttgttta
     1801 tcatcctcaa taattttata aatcaaacct atataatcat gaatgctggc aaaaattttt
     1861 tttaagtcaa gttctaaatc ttcttcgaaa acacatttaa tttctcctac tgataattga
     1921 tactctatat tacatgactt aattagtttt ttagatcccc cctccagata ggcatatgtt
     1981 tcaataatta tgttcttttt attgcttggc aaatttccgt tatttattgc ataaattaaa
     2041 aatgactgtc tatttagccc ataatctaat acaacttctt catactcata tttctttaaa
     2101 tatttaatat gaaaatatgc tgaattaatc aaaactcgag tgttactgtt gttatttatt
     2161 gttgttctat tgtgtataaa attgtatagg ttgtcatatt ttcttggttt agtgaactac
     2221 tcaccactta gctaaaccta acggtttctt acgtttgaag tgggagcttc ttgggaagag
     2281 agcatacttg atagcgtatt actttactaa cagaggtgcc tcttatttac caagctatcc
     2341 ccgtagttcc tacggttctt gtttatttga tctaagccaa tcccatagag tgtagcctta
     2401 gaccttcggt caggatattg atactagcgt tgatatctcg gtcatgatga gtatgacaaa
     2461 tagggcaagt ccattttcga atttcgagag atttcttgcc gtctttatgt ccacaattcg
     2521 aacagatttg gctagatgga aaccacttat ctactttgat gattttccga ccgtaccagt
     2581 cagccttgta ttgtaattta gacacaaaac tagaccaaga aacatccgaa atactttttg
     2641 ctagtttatg attacgcaac atgccttttg tgtttaagtc ttcaatacag atgatatcgt
     2701 gatttttgat aatttctgta ctcaacttat tcagaaaatc agtacgttga ttcattactt
     2761 tttcatgcaa tcgtgctact ttacgttttt gtgtttgata atttctagct tcaaacagat
     2821 tgataccttt ttgtttagct aataaggcac gtcttgacaa cttacgttgt tcacgtttga
     2881 gtttcttttc cattttggac gtaaatttat tattatcaaa tttttgaccg gtagaaagaa
     2941 ttgcaaagtc tataatacct aggtcaatac caacagcaga attagattta ggtagttcgc
     3001 gaacttcttc tttgcataac aaagaaatat aatatttacc gctagaatga cgtgatattg
     3061 tagc
//
LOCUS       DADQDV010000160         2952 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.168, whole genome shotgun sequence.
ACCESSION   DADQDV010000160 DADQDV010000000
VERSION     DADQDV010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2952
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.168"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            89..406
                     /locus_tag="J8S10_003051"
     CDS             89..406
                     /locus_tag="J8S10_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HAZ9631573.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNSSIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIAAIITQLFLVFGEKKR
                     SKK"
     gene            complement(497..862)
                     /locus_tag="J8S10_003052"
     CDS             complement(497..862)
                     /locus_tag="J8S10_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631574.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            1070..1552
                     /locus_tag="J8S10_003053"
     CDS             1070..1552
                     /locus_tag="J8S10_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631575.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALIVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSTFSLLPRLIIGP
                     NGLSESGLKDLAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            1749..2639
                     /gene="pstS"
                     /locus_tag="J8S10_003054"
     CDS             1749..2639
                     /gene="pstS"
                     /locus_tag="J8S10_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HAZ9631576.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
BASE COUNT         1008 a          460 c          566 g          918 t
ORIGIN      
        1 ttttaaaaca tcacaaggaa aaacttaact atggtattat ctaaacataa ttttttcggt
       61 atttaatatt taattaggag gtaatatttt gcttttttat agtaatttta tcttaatagt
      121 agcgatatta ttacttctga atatatggat ttttgatagg agtagaaatt caagtatagg
      181 ttttagaact aaacgaagtt tgtcttctaa aaaaaattgg gtatactcac aaactatttt
      241 ttatggagga attgttttaa ttagtttact ttcttcaaca ctttattctt tgaatattat
      301 agatgtttcc acctcaaatt caatatctat tattggaatc attattgctg caattattac
      361 acaactgttt ttagtgtttg gagagaagaa aagaagtaaa aaatagaaaa actagtgata
      421 gttttggtga tataagaaaa acatatatgt ataaaaagaa gaaagtagct tctctttgta
      481 catatatggt ttgtttttat ggatgccgag cttttttata agataaggct accgcccata
      541 acgacccaag gatttgtgga actaagtaaa tacctgcaag aagcaagatc agctgggtcg
      601 gttttaaagg atgatagaag taacgccatt cagtaaaatt ggcgcaaaat aaataggaag
      661 tgacagtaga tataatattg gcaatgaata aagatataat acgcctgttc ctttgaaaat
      721 aatatccagc aaaaagagat aaaaatatca atgtgatgaa cccgcttacg gaatgataac
      781 gaaaatcaag cagtaaggcg aaatgcacat aaggaacaaa agataaaagc aacggaaggt
      841 ttttccagca agtttttatc atctttcatc accacctaac aagtgttatt attttgttag
      901 ttttattgta aattgaatcc tgcaataatc aattactttt tcattatttc tagattaaat
      961 gaataaactc tcatgccatt atctctaaaa aaaaagtttt tccccctaat ttttttagat
     1021 agaaaattgt atagtatgat gagagaaaaa gtagtttggg ggaacgttaa tgagaagaaa
     1081 agcagtaatc gatcggcttt atttattttt ttggtttttt cctatcgttt tgctaccttt
     1141 tacatgggta aatgctgttg tacaaggtgc ggagatatta ggcctgatcc aaggaagcgg
     1201 atttgtggtt tctaggaatt ttccagcttt gattgttttc tatttagtga taagtgtagg
     1261 tctcttatta ccaaaatctc tgatcaatca ctacaattgg cagctgcttt acttttcttg
     1321 cttattagta tttacatcta cgttttcttt gctgcctcgc ttgattatcg gccctaatgg
     1381 tttgagcgag agtggattga aggatttagc ttattcctcc atgtatttct tgacgatcaa
     1441 accatggttc tatttagtaa ttgcctcatt tattcttgca acattttttt acttctggac
     1501 agaaatcagg ataaaaagtg aacgatctgt atctataaaa aataactatt gatggtggat
     1561 catcagtaaa aaaacatatg agctgcgtaa aatgcatgtt tctcatatgc tttttttatt
     1621 attatgtaaa gaatgcgaaa aacgtttaca tgatttttac ataacttaac tatattttta
     1681 cagcaaccat acgagggatt tacagtcgac tgataaactt tagttgtaaa taagaaagga
     1741 gcaataaaat gaaaaaagta ttgtttactc taggtatgat gggaattctt ttagccggat
     1801 gcggctcagg atcaggaaat acagatggct ctgccacaca aaataattca agtgactcaa
     1861 atgaacaagt aaaaatcgtt gcggtaggtt cgacagcatt acagccgtta gtcgatgcag
     1921 cacaagaaag ctttgtacaa gaaaatccaa attatcaaat ctctgtacaa ggaggaggaa
     1981 gcggaactgg tttgagccaa gtcgaagctg gagcagttac tatcggaaac tctgatgtat
     2041 ttgcagaaga aagagacgga gttgatgctt caaaattagt ggatcataaa gtagcagtgg
     2101 tcgggatggc accaatcgtc aataaagata cagatgtcaa agatatcacc aaacaggaat
     2161 tgattgatat ctttacagga aaaatcacta actggaagga agttggcggg aaagatcaaa
     2221 aaatcaacgt cgtgaaccgt gcaaacggca gcggtacccg cgcgacattc gaaaaatggg
     2281 gactggatgg tgctacccct gtgcagtccc aagaacaaga ttcatcagga acagttcggc
     2341 agctggtaag tcaaacacca ggagcaatca gctatttagc tttctcatat ctcgatgatt
     2401 ccacacaagc actaagtatc gacggtgtag aaccaaaaga agagaatgta gcagataaca
     2461 gctggggaat ctggtcatat gaacatatgt acacgaacgg aaaaccttcc cctgaagtcc
     2521 aaaaattctt agactacatg atgacagaag aaatccaaga aggacctgtc aaagaattgg
     2581 gctatttacc aatcacaatg atggaagtag aacgtgatca cgaaggaaat atcaaataac
     2641 tagcagataa acatgccacg gtagtcgtta ctattaagga aaaatcaact atgtttcccc
     2701 acatatacat ttttccttta attgtgaaaa atagttcctc atattttgcc gttttttgag
     2761 ctaataccga gggtcagctg attgaacacc gtttattcga aaaaaagagc tacgacatag
     2821 aactgtcgta actttttttg gctcttcgtc aaatcgtgtt ggtgaagaca aatttgaata
     2881 aaacttagac cgatatgcgg cgcgttctgt gcgccgcata tttttttagt tttcaaagat
     2941 cagaccttgt tg
//
LOCUS       DADQDV010000161         2947 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.169, whole genome shotgun sequence.
ACCESSION   DADQDV010000161 DADQDV010000000
VERSION     DADQDV010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2947)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2947)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2947
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.169"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(449..865)
                     /locus_tag="J8S10_003055"
     CDS             complement(449..865)
                     /locus_tag="J8S10_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631577.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIERNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMSEIIAEFADLYLKDTGILIGTNSKVYQETKEKI
                     EKQLNPSKRNQPKNRQKETNQTFTSKNFDPTNFLKR"
     gene            complement(867..1148)
                     /locus_tag="J8S10_003056"
     CDS             complement(867..1148)
                     /locus_tag="J8S10_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631578.1"
                     /translation="MDILVRKIDSKVIAKIDKRCQELTNKTGKKWSRNRYLKVLIEND
                     FDHALMHYKKDQFDLLLEKFIAIQEKNTETLNEYVRTNNQLIETLIGGR"
     gene            1948..2922
                     /locus_tag="J8S10_003057"
     CDS             1948..2922
                     /locus_tag="J8S10_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HAZ9631579.1"
                     /translation="MSKRGTIINEWEKLNRISNRRLNAQTMCTPLKMQWSIDRITIVG
                     TLRENIYYHTPHDVLILDFEQLMRLNEGNGYLKAVGNNGWQLLDQHEENIAYIEILKF
                     QEGKGRIDFNPNKISQFLAGSMKNFIHDLFLEPHFSRADIACDIIDVPDDFITQYRVV
                     DPVSFKPIYGRSGKLETAYWGSRASERQIRMYNKKLEQERKRKVVPKEIDTWWRLELQ
                     LRRGKATDWHAMVHESLDSFASPHYLPEDVKVTDRMMITALITEHSYWGQIHRNSKYK
                     YRELLKQESQNDELTNHLRETFSESADDLKRELDTWLQGLDVTEVGAE"
BASE COUNT          913 a          438 c          603 g          993 t
ORIGIN      
        1 aaaaaaactt gctgatgaat tgggtgtatc gaaaaatacg gtgcgcaatc aactggtcaa
       61 ttcgggattt gaccttgctc agtataaaga aaaaaatgca gtggtcaatt gaccgaaatt
      121 tatgtctttg ggttttgggg ttttaaaacg aaaaaaaggg ggcgattttc gccccctttg
      181 ctctatgtga aaaatttgtt atacttattt tatccttaaa acataccaat ctttttctta
      241 tttagctgct cgtacgagca gcttttttta cgattatgaa ttcaaatcat gtatttataa
      301 tttttttgtt tttatctttt tttctgttat ttcttctgaa attcgttttt ttcattcaat
      361 tggttactat cttattgtaa atgttgctat taagatggtg atcctaccca aaaaataaac
      421 caggaattta aatctcctgg tttatttttt atctttttag aaaatttgtt gggtcgaaat
      481 ttttagaagt aaatgtttga ttggtttctt tttgacgatt ttttggttga tttcgtttgg
      541 agggattaag ttgtttttca attttttctt tcgtttcttg atacacttta gaatttgtgc
      601 caataagaat acctgtatct tttagatata aatcagcaaa ttctgcaatg atttcggaca
      661 tgatggaaat ttcttttccc atagcattta gtttggcttg gttgctggta gtcgtagtat
      721 tggtatcagg ttcataactc atacataaaa aacgaatggc ttccgagtaa ttgttgatat
      781 ctggatttct ttcgataatg gaatctaaaa cgtccacgtg actgggataa agggtaacgt
      841 gtttttgaac agaagttttt ctcatgttat cttcctccga taagtgtttc aatgagttgg
      901 ttgtttgtac gaacatattc attcagcgtt tcagtatttt tttcttgaat agcgataaat
      961 ttttcgagta ataaatcgaa ttgatctttc ttgtaatgca taagtgcgtg gtcaaaatcg
     1021 ttttcgatta ggacttttaa gtagcgattt cgactccatt ttttgccagt tttatttgtg
     1081 agttcttggc aacgtttgtc tatttttgca ataacctttg aatcgatctt ccgaactaaa
     1141 atgtccatag aaaaactcct ttcgcatttg tgtataattt atgtatatca tacgaatata
     1201 gtatttgtat agctgttttt tgctaaaata ctatacataa gctagccacg atggcgaaaa
     1261 agtgatatca aatttttttc tgagaaacgt gataggcaca gcctatctac ccactttttt
     1321 tagaaagtgg gtacacgttt ccttatgctc tttataaaat ggtgatgtgc gacttttttc
     1381 tgttcgtaaa aataaaaaaa gtttacgaaa atgaaactaa actgaacgat tatgacgggc
     1441 atgtaatcaa gatgaaatga ttttataagc gcgtattttg cgttctaaga cgttttagcg
     1501 ttcatttcgt ttagttatcg gcacaatcgt taaaacacgt aagagaagcg agaatggagc
     1561 ctgtaaggcg actggtagcg aaacggcgtg ttagattgtg caagccgaga actgaatgaa
     1621 atgaagagcg gaagcgtgaa ataatttcgg caggaggagg ctcaaggggt tcggggaatg
     1681 aaattccctg aggtcttttt atttttttaa gaggagtgct ataatcaaag aaaacgagaa
     1741 aaaagagcaa aataaaagcc gaacggtgtt ggaagcaccc ttcggctaat tacggaaact
     1801 actcacctag ttccgtaact caaattcatt atacgaatat ttttaggttt cttcaagcta
     1861 gagatttttg gatatggatt tttagagtta cgtgaactct ggaaattctt tccaaaaatc
     1921 tcttttttct ttgaggagga acaaaatttg agtaaacgtg gcacgatcat aaatgagtgg
     1981 gaaaaactta accgcatatc taacaggcgg ttaaatgcac aaactatgtg caccccctta
     2041 aaaatgcaat ggtcaattga ccgaattacc attgttggta cattaaggga aaatatttat
     2101 tatcacactc cccatgatgt gttgatttta gattttgaac agcttatgcg tctaaacgaa
     2161 ggtaacggat atttaaaagc ggttggaaat aatggctggc aattactaga ccaacatgag
     2221 gaaaatatag cttatattga gattcttaag tttcaagagg gaaaagggcg gattgacttt
     2281 aaccccaata aaattagcca atttctggcg ggctcgatga agaactttat ccatgattta
     2341 tttttagaac cacatttctc acgtgcagat attgcttgtg acattattga cgtgccagat
     2401 gatttcatta cccaatatcg ggtggttgat cctgtttctt tcaaaccaat ttacggtcgg
     2461 tctgggaaac tggaaacagc atattgggga agtcgtgcta gtgaacgaca gattcggatg
     2521 tataacaaaa aattggaaca agaaagaaaa cggaaagttg ttccgaaaga aatcgatact
     2581 tggtggcgac tagaattgca attgcgaagg gggaaagcaa ctgattggca tgcaatggtt
     2641 catgaaagtt tagatagctt tgcaagtcct cactatttgc cagaagatgt gaaagtaact
     2701 gacagaatga tgattactgc tcttataacg gaacatagtt actgggggca aattcataga
     2761 aattcaaaat ataaatatcg tgaattgtta aagcaagaaa gtcaaaatga tgagttgacg
     2821 aatcatttgc gagaaacatt ttcggagtcg gcagatgatt tgaaacgaga attagataca
     2881 tggcttcaag gacttgatgt gacggaagta ggtgctgaat gagtgattcg atagaaaaaa
     2941 tgaccct
//
LOCUS       DADQDV010000162         2857 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.170, whole genome shotgun sequence.
ACCESSION   DADQDV010000162 DADQDV010000000
VERSION     DADQDV010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2857)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2857)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2857
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.170"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            562..843
                     /locus_tag="J8S10_003058"
     CDS             562..843
                     /locus_tag="J8S10_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631580.1"
                     /translation="MDILVRKIDSKVIAKIDKRCQELTNKTGKKWSRNKYLKVLIESD
                     FDRQLTTYKKDQFDLLLEKFIAIQTKNTQVLNDYVHTNNQLIETLIGGK"
     gene            845..1261
                     /locus_tag="J8S10_003059"
     CDS             845..1261
                     /locus_tag="J8S10_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631581.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIERNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMSEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKT
                     EAKLNPSNRNRPKNHQKETSQTVTSRNFDPTNFLKR"
     gene            complement(1422..1688)
                     /locus_tag="J8S10_003060"
     CDS             complement(1422..1688)
                     /locus_tag="J8S10_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631582.1"
                     /translation="MAFRFRCDRGGRKMTEKFPYEYYQNLEKLESAIQLVKLDLLDEN
                     LLKYKNITPERKGKLKKMQQLFDEEDGISDVIFDTWSEFHGEYN"
     gene            complement(1646..2620)
                     /locus_tag="J8S10_003061"
     CDS             complement(1646..2620)
                     /locus_tag="J8S10_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HAZ9631583.1"
                     /translation="MGKKRTIVNEWEKLTAPSNRRLNVGESVKMIKMDWSIDRITIVG
                     TLNENIYYHTQNDVLILDFEQLMRVNEGNGHLKAVGNNGWQLVDQHEENIAYIEILKW
                     QEGKGRIDFNPNKISQFLASSMKKFIHDLFLEPHFSRADVACDLIDVPDEFITQYRVV
                     DPVSFKPIYGRSGKLETAYWGSRASERQIRMYNKKLEQEAKRKIVPKEVETWWRLELQ
                     LRRGKATDWYEMVQESLDSFASPHYFPEDVKTLDRVMIKGLLYDHSEWSTISRDLKYR
                     LRKLLKQESQNDELTNHLRETFEESADELKRELDTWLLGLDVTEEEEK"
BASE COUNT          926 a          624 c          397 g          910 t
ORIGIN      
        1 aaaaaaataa aaagacctca gggaatttca ttccccgaac cccttgagcc tcctcctgcc
       61 gaaatcattt cacgcttccg ctcttcattt cattcagttc tcggctttca caatctaaca
      121 cgccgtttcg ctaccagtcg ccttacaggc tccattctcg cttctcttac gtgttttacc
      181 gattgtgccg acaactaaac gaaatgaacg ctaaaacgtc ttagaacgca aaatacacgc
      241 ttataaaatc atttcatctt gattatatgc tcatcataat cgttcaattt gacatcattt
      301 ccgtaaactt tttttatttt tataagcaga aaaaagtcgc acatcaacat ttttttaaag
      361 agcataagga aacgtgtacc cactttctaa aaaaagcggg cagataggct gtgcctatca
      421 cgtttctaag aaaaaaattt gatatcactt tttcgccatt gtgactagct tatgtatagt
      481 gtttcagcaa aaaacagcta tacaaatact atattcgtat gatatacata aattatacac
      541 aaatgcgaaa ggagtttttc tatggacatt ttagttcgga agattgattc aaaggttatt
      601 gcaaaaatag acaaacgttg ccaagaactc acaaataaaa ctggcaaaaa atggagtcga
      661 aataaatatc taaaagtttt aatcgaaagt gattttgacc gtcaacttac gacttacaaa
      721 aaagaccaat tcgatttatt actcgaaaaa tttatcgcta ttcagacaaa aaacactcaa
      781 gtactaaacg actatgttca tacaaataat caacttattg aaacacttat tggaggaaaa
      841 tagcatgaga aaaacttctg ttcaaaaaca cgttaccctt tatcccagtc acgtggacgt
      901 tttagattcc attatcgaaa gaaatccaga tatcaacaat tactcggaag ccattcgttt
      961 tttatgtatg agttatgaac ctgataccaa cacgactact accagcaatc aagccaaact
     1021 aaatgctatg ggaaaagaaa tttccatcat gtccgaaatc attgcagaat ttgctgattt
     1081 atatctaaaa gatacaggcg ttcttattgg cacaaattct aaagtgtatc aagaagtgaa
     1141 agaaaaaacc gaagctaaac taaatccgtc gaatcgaaat cgaccaaaga atcatcaaaa
     1201 agaaacgagt caaacagtca cttctagaaa tttcgaccca acaaattttc taaaacgcta
     1261 aaaaataaaa cgagaatttt tttatttctc gttttatttt ttaggaaagc cggtcttaca
     1321 gcaagatttg caagttaccg gtaacttgcg gaaaagaaga agccgctcac gcgacttctt
     1381 ctttttgcat tttctgaaag ctaccacaat tcctaacttc gctaattata ttctccatga
     1441 aattcgctcc atgtatcaaa aatcacatct gaaattccat cttcttcatc aaataattgc
     1501 tgcatttttt tcaatttacc ctttctctct ggcgtaatat ttttgtattt tagtaaattc
     1561 tcatccaaca aatccagctt gaccaactga atagcactct ccaatttttc tagattttga
     1621 taatactcgt atggaaattt ctcagtcatt tttcttcctc ctctgtcaca tctaaaccta
     1681 aaagccatgt atccaattct ctttttaatt cgtctgcaga ctcctcaaat gtttctcgta
     1741 aatgattcgt caattcatca ttttgacttt cttgcttcag caatttcctt agccgatatt
     1801 tcaagtcacg actaatagtt gaccactcag aatggtcata caacaacccc tttatcatca
     1861 ctctatccaa cgtttttaca tcttcaggaa aataatgcgg actagcaaaa ctatccaaac
     1921 tttcttgaac catctcatac caatcagtcg cttttccacg gcgcaattgt aactccaaac
     1981 gccaccacgt ctcgacttct ttaggtacaa tttttcgctt tgcttcctgt tccaacttct
     2041 tgttgtacat ccgaatttgg cgttcgctgg cacgactacc ccaataagcc gtttctagct
     2101 taccagagcg tccataaatt ggtttgaagg acacagggtc aactacacga tattgtgtaa
     2161 taaactcatc aggcacatca ataagatcgc aggcaacatc cgctcgtgaa aaatggggct
     2221 ctaaaaataa atcatgaata aattttttca tagagcttgc taaaaattga ctaattttat
     2281 tggggttaaa gtcaatccgc cctttaccct cttgccattt caaaatttcg atataggcaa
     2341 tattttcttc gtgttgatct accaattgcc aaccattatt cccaacagct tttaaatgac
     2401 cattaccttc gttcactcgc attaattgct caaaatctaa aatcaacaca tcattttgag
     2461 tgtgataata aatattttca ttcaaagttc cgacaatcgt aattcggtca atcgaccaat
     2521 ccatttttat catttttacg ctctcaccga catttaaccg cctgttagag ggggctgtta
     2581 atttttccca ctcattcaca attgttcttt ttttacccaa attttgttcc tcctcaaaga
     2641 aaaaaagaga tttttggaaa gaatttccag agttcacgta actctaaaaa tccacatcca
     2701 aaaatctcta gcttgaagaa acctaaaaat attcgtataa tgaacttgag ttacggaact
     2761 aggctagtag tttccgtaaa ggtcgagagt gttagcgcac tgctcgacta tttttttgct
     2821 cttttttctc gttttctttg attatagcac tcctctt
//
LOCUS       DADQDV010000163         2687 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.171, whole genome shotgun sequence.
ACCESSION   DADQDV010000163 DADQDV010000000
VERSION     DADQDV010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2687)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2687)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2687
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.171"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(245..1108)
                     /locus_tag="J8S10_003062"
     CDS             complement(245..1108)
                     /locus_tag="J8S10_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin zeta"
                     /protein_id="HAZ9631584.1"
                     /translation="MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGS
                     GKTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAL
                     ISRLSDQGYNLVIEGTGRTTDVPIQTATMLQSKGYETKIYVMAVPKIESYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKMESLQLPTP
                     PIPKTPKLPGI"
     gene            complement(1110..1382)
                     /locus_tag="J8S10_003063"
     CDS             complement(1110..1382)
                     /locus_tag="J8S10_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HAZ9631585.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEV
                     NLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYSKQILNKEKVA"
     gene            complement(1399..1608)
                     /locus_tag="J8S10_003064"
     CDS             complement(1399..1608)
                     /locus_tag="J8S10_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HAZ9631586.1"
                     /translation="MGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAK
                     NGGNVKEVMDQALEEYIRKYLPDKL"
     gene            complement(1707..2561)
                     /locus_tag="J8S10_003065"
     CDS             complement(1707..2561)
                     /locus_tag="J8S10_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAZ9631587.1"
                     /translation="MEKEKLKILEELRRILNNKNEAIIILNNYFKGGVGKSKLSTMFA
                     YLTDKLNLKVLMIDKDLQATLTKDLAKTFEVELPRVNFYEGLKNGNLASSIIHLTDNL
                     DLIPGTFDLMLLPKLTRSWTFENESRLLATLLAPLKSDYDLIIIDTVPTPSVYTNNAI
                     VASDYVMIPLQAEEESTNNIQNYISYLIDLQEQFNPGLDMIGFVPYLVDTDSATIKSN
                     LEELYKEHKEDNLVFRNIIKRSNKVSTWSKNGITEHKGYDKKVLSMYENVFFEMIERI
                     IQLENEKE"
BASE COUNT          753 a          484 c          416 g         1034 t
ORIGIN      
        1 taaatttgga aagttacacg ttactaaagg gaatgtagat aaattattag gtatagggca
       61 cctctaataa ctaccaatta attcacctca aaatgaaatt agaaaaaaac agcgaaattt
      121 ttaaatctat ttcttatcga tacaaattcc tcgtaggcgc tcgggacccc aacatgagga
      181 aatgttttta taaaaaaaga gtagttaccg ttttttggta actactcttt tcctttttta
      241 aggtttaaat acctggaagt ttaggtgttt tgggtattgg tggtgtaggt agctgcaagc
      301 tttccatttt ttgttgaatt gctttaaatt caggggtttc ttggtgttga ttttgaacca
      361 ttttttgctc tattctctcc aaagtcggtt gaatttcttt ccctgatact ttacgattta
      421 attctctttc taaggtctct ttcggactaa tggaaggcgt ttctaagctt gaatagagtt
      481 tcactccttc tctattgtaa agccttatat cgctaaataa gcccgtttta tgaagggttt
      541 ctaaattggt cggtaagttt ttgacaacaa tatcatgcgc ttgttttggt gttgccctag
      601 ctgtcattgg atcatctgca tacatggttt catatcgttc aatcgttcct aagtatgatt
      661 caattttcgg tactgccatg acgtatattt ttgtttcata acctttagat tgaagcattg
      721 tggctgtttg aatgggaacg tctgttgttc gtcctgttcc ttcaatcact aaattatagc
      781 cttgatcgct taaacggcta ataagtgctt ctgtcatgcg attcgaataa ggggtaacgt
      841 gttttactac gtctttttca tagagtttca ctaattcgtc aaaatttggg tgctgttgtt
      901 taaaggtatc attatcaatg acaataacat tcccttgtgt ttcttcaaaa attgctgatc
      961 gcaaactggt tttccctgac cctggttgcc caccaagtaa aaaagcggtt ggcgattcaa
     1021 ccgctagtct atttttagtt agtcgttcaa cattcttttc taaacgatct tcaaattgct
     1081 tttcggtgaa gtcagtaata ttcgccatgt taagccactt tctctttatt caaaatttgt
     1141 tttgaatatt gattcattga ccgccaatac tcatgaatag cttgtaattc ttcaaatggt
     1201 tgttgaaata aatcaacttc ttgtgccact tctaattgat ttaaaagatt cacttctagt
     1261 aaacgagtat ttttagtatc tagttcatga ttcaaaacat aatttaatac ccgattataa
     1321 acacttgccg ataactcatt aatgatttca atttcaaatg ttttttcata cgtaactgcc
     1381 atttcatttt cactcctttt aaagtttgtc aggtaaatat ttccgtatat attcttctaa
     1441 ggcttgatcc ataacttctt ttacgtttcc gccattcttt gctgtttcga tttttatgat
     1501 atggtgcaag tcggcacgaa cacgaaccgt cttatccccc attatatctt tttttgcgct
     1561 gattggcgta tcatttcgtt ttgctttctg tgcgcctaaa tttcccacga tcgctcactt
     1621 ctttctattt cttcttacta tttattttat catcacctat cacaaatcac aagtgatttg
     1681 tgattaatca cttgtgattt gtgattctat tctttttcat tttctaattg aatgattcgc
     1741 tcaatcattt caaaaaatac gttctcatac atagacaaaa cttttttgtc atagcctttg
     1801 tgttctgtaa tgccattttt agaccaagta cttactttat tacttcgctt gataatattt
     1861 cggaaaacca aattatcctc tttatgttct ttgtacagtt cttccaggtt tgattttatc
     1921 gttgcgctgt ccgtatcaac taaataagga acaaaaccaa tcatatctag tccagggtta
     1981 aactgttctt gcaaatcaat caaataggaa atatagtttt gaatgttgtt tgtactttct
     2041 tcttctgctt gtaaagggat cataacgtaa tcactcgcca cgattgcatt atttgtataa
     2101 acgcttggcg ttggtacagt atcaataata ataagatcat agtcactttt taaaggtgct
     2161 aaaagagtag caagcaatct actttcattt tcaaacgtcc atgagcgagt taattttggc
     2221 agtaacatca aatcaaacgt gccagggatc aagtctaaat tatcagtcaa atgaataata
     2281 gaagaagcca agtttccatt tttcaagcct tcataaaaat tgacacgtgg caattctacc
     2341 tcaaaagttt ttgctaagtc ttttgtcaat gttgcctgta agtccttatc gatcattaaa
     2401 acttttaaat tcaatttgtc tgtcaagtaa gcaaacatag tcgataattt ggactttcca
     2461 acaccacctt taaagtaatt attcaagata ataattgctt catttttatt gtttaaaata
     2521 cgtcttaatt cttcaagtat ttttagtttt tccttctcca taactacgcc ccattctttt
     2581 tttgtatagt aatattgtat cattaagaat cacaaatcac aagtgatttg tgattaatca
     2641 cttgtgattt gtgataagtg atttgtgatt aatatataaa agccctc
//
LOCUS       DADQDV010000164         2670 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.172, whole genome shotgun sequence.
ACCESSION   DADQDV010000164 DADQDV010000000
VERSION     DADQDV010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2670)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2670)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2670
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.172"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..235
                     /locus_tag="J8S10_003066"
     CDS             <1..235
                     /locus_tag="J8S10_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004292767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HAZ9631588.1"
                     /translation="NSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFH
                     QAMKHAKVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            405..665
                     /locus_tag="J8S10_003067"
                     /pseudo
     CDS             405..665
                     /locus_tag="J8S10_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase"
     gene            828..1493
                     /locus_tag="J8S10_003068"
                     /pseudo
     CDS             828..1493
                     /locus_tag="J8S10_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000284571.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
     gene            1529..1774
                     /locus_tag="J8S10_003069"
     CDS             1529..1774
                     /locus_tag="J8S10_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAZ9631589.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRL
                     LLGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
     gene            1877..>2670
                     /locus_tag="J8S10_003070"
     CDS             1877..>2670
                     /locus_tag="J8S10_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HAZ9631590.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIY
                     YNSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIK
                     RVEQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETY
                     PNALQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYC
                     INEKKAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLY"
BASE COUNT          943 a          394 c          513 g          820 t
ORIGIN      
        1 aaacagtgtc ttaataaaac ttacccgcca taccacagat gttccagata aatattggaa
       61 gctatatacg tactttgttt caaaatgggt caatcgagaa tatcgtcaac tgtttactaa
      121 aaatcagttt catcaagcaa tgaaacacgc caaagtaaac aatttaagta ccgttactta
      181 tgagcaagta ttgtctattt ttaatagtta tctattattt aacgggagga aataattcta
      241 tgagtcgctt ttttaaattt ggaaagttac acgttactaa agggaatgga gataaattat
      301 tagatatact actgacagct tccaagaagc taaagaggtc cctagcgcct acggggaatt
      361 tgtatcgata aggggtacaa attcccacta agcgctcggg accccttgta ggaaaatgtc
      421 ctaagtgtgg caacaatatt gtattaaaaa aatcgtttta tggttgttca aattatcctg
      481 aatgtaagtt tactttagct gaacatttta gaaagaaaaa actaaccaaa acgaatgtaa
      541 aagaattact ggagggaaaa gaaaccctgg taaaaggaat caaaaacaaa gagaaaaagc
      601 cctacaatgc cgttgtaaaa attggggaaa agggatatat tgattttatc tctttttcaa
      661 aataaacatg gggctgaccc aaaagtagct cctatatgaa aaatagaggt ctttccattt
      721 agatagtagt ggaaagacct ctatttatct tttgaaagtg aatacaaaaa taaagcacac
      781 tctgctataa tataggtgat taatccattt gagagaggtg ctttatcatg tatcaaaatt
      841 ataccataaa ccaactttgt ttgcctatag atcttgaaat taaattagaa gaaaatgatt
      901 ttgctcatgc cattgtgcag tttgttgact ctattcccga tgaagtcttt cttccttatt
      961 atcaatctat gggtagaccc caatatcatc ctcgtatgct actttccatt attctttgtg
     1021 cctatattca aggggtttat tcgggccgcc aaatacaaaa tatgctgata gatagtattc
     1081 ggatgcgcta cttatctcaa gagcaattcc ctaactttcg tactattaat cgttttcgcg
     1141 ttcatccgat tatgaacgat attctagatc attcatttgt tcaatttcgt gagctactgg
     1201 ttcaaagtgg cttaatcagt ggcagtgctc tatacattga tggtacaaaa attgaagcgg
     1261 atgcgaataa atactctttc gtttggaaaa aaagtatttt aaagtataag gatagccttg
     1321 atcaaaaagc ccttgaaaac taccaacaaa tggtggaaac aaaaatctta cctgagttaa
     1381 tagatgattt aaaggatgaa ctttctatag aagagattga aaggattcgt caatctttgg
     1441 aagaaaagga aaatcaatta attgaagcga ttgaccaaac cgaaacagta gaagggggct
     1501 gacccattat taataaggag tggacaacat gattgatgta aatgagctat tggaagaagc
     1561 tattagagaa actgaaaatc taaatgatgg cgaagttttt cttgttaaag atttattcaa
     1621 gggatatgtg gggaatagga tacccagaaa ggatcgactt ctgcttggaa cgttattttt
     1681 aaaccatgtt agcaaaatga atggtaattt aaaggctatt gaaaagactt catctaatca
     1741 gcagaggtat aaaaagacaa ttgataagtt ttaactatct tttgtgaaat taaaaaaatt
     1801 ataaatatgt tgagtagaag caaaagattt ggcttggaat ttttacagca gtgaatcgat
     1861 aaaaggagca tgcttgatgg tagataatat tattaaatca gtagcagaga aattatcctc
     1921 tctgtcttat atagaaggta ttgttttagg tggttcacgt gcaaggggca cccatacaga
     1981 ggattcggat atagatatcg gcatctatta caattcagaa tcatttgaca taaatactat
     2041 taatcaattc gctacaaagc tggatgatga gcatagaaat aaccttgttg tacctcccgg
     2101 agcatggggt gattggatta atggcggcgg atggttagtc ataaacgggt atcatgtgga
     2161 tttaatttta cgtgatatta aacgtgtgga acaaataatg aaagatacag agcacggaat
     2221 tgttactgcc aattatcaga ctgggcatcc ccatggttat attagtgcaa tgtatcgagg
     2281 agaattagcg attagcaaaa tactatatgc taagaatgaa agcttatgcg aattaaaaaa
     2341 acaggcagaa acttatccca atgctttgca gaaaagttta gttaactttt ttatgtttga
     2401 agcagggttc tctttaatgt ttgtaaaagc aaattcggga acagacgata aatattatat
     2461 tgcgggtcat gtttttcgta tagtttcatg tttaaatcaa gtgttatttg catgtaataa
     2521 tgcttattgt atcaacgaaa agaaagctat aaaactgctt gaaacttttg aacataaacc
     2581 tgaaaaatat accgagaagg taaatcatat ttttgaagta ctcggtatct cactttttga
     2641 atgctacgac atgaccgaga agctttataa
//
LOCUS       DADQDV010000165         2637 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.173, whole genome shotgun sequence.
ACCESSION   DADQDV010000165 DADQDV010000000
VERSION     DADQDV010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2637
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.173"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            512..2356
                     /locus_tag="J8S10_003071"
     CDS             512..2356
                     /locus_tag="J8S10_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAZ9631591.1"
                     /translation="MNYKQTAEEVLQYIGGEENISHLEHCSTRLRFTLKDNSKVNMSQ
                     LEKVDGVMGVRQNVQCQVIIGNDVVEVYDEVKALLGDNVSNTEEAPKQKQKLGSVLLD
                     FIISIFQPLIPAIAGGGVLKSLLLLASILGLISDQSQTYQILNLVGGAPLYFLPILVA
                     MTTANKLKVNQLVAVSAVGALILPEMTAMLAEGATFLSFGLDNIAYASQVFPAILTVL
                     FYAQLEKWFTKVSPKPIRIFFVPMMSLLITVPIALLLLGPLGYNVGTAFSSIIVSLYN
                     QFGWVATGVLAAVLPLMVVTGMHKAMIPYAVSSMSELGAELLYLPASLAHNISEAGAC
                     FAVSIKTKDKKLKSTAVSAGISALFGITEPALYGVTILHKRVLYAVMFSSLIGGAFAG
                     IVALQAFALVGPGIASITMFADKADPMNLVWAFAVSGISFVVAFAAALVLYKDKEVVN
                     EVETKMETAVVSDAVLSSPVNGKVISLSEVKDTVFSSGMVGDGVAIIPEEGILVAPED
                     GEITMVFETKHAIGLKTANGAELLFHIGIDTVQLEGKGFEAFVRSGEKVAKGQKLIAF
                     DIDLIKEAGFDPTVICVVTNKDNYTIRSFNLEKLVTNDSDLLAISPIA"
     gene            2412..>2637
                     /locus_tag="J8S10_003072"
     CDS             2412..>2637
                     /locus_tag="J8S10_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HAZ9631592.1"
                     /translation="MTNTTSFPKGFLWGGAIAANQVEGAWNVDGKGLSVADMATYKPN
                     LDNKDFAAHMHVTLQSIKEASEDKSDKWYPK"
BASE COUNT          847 a          426 c          543 g          821 t
ORIGIN      
        1 aagcgctaat ctaattcact gtattatcat tttttagtag tatagcacaa ttatgaatgc
       61 cttttcttta tatcaaataa agtttatata aaaaacctca tcctgcaaga aagaaaaaat
      121 gaacccattc tttttatact aggtcttaaa aagacagaac atctgctaga agatagaaga
      181 gaataagagt tatatatgtt ggaagatatt cttagaaaaa agacaaaact tttagaacac
      241 gaaaactata ttgaacgaat aaaatgaaaa aatgattaaa aaatcatttt attatttacg
      301 tttacattct aatatgttaa attgaatata acttaaacag gcatgtgact ggtaatgcag
      361 gcaggaccta aataagttga ataacaatgt atgcgtttca atacacgttt gccttgttgt
      421 caatttattt agtttctgcc tgttttttgt gttgaggatg gccacttcga ctcaaaagtt
      481 catcactcaa aaaagaaaag agggaaacac catgaattac aaacaaacag cagaagaagt
      541 attgcagtac atcggtgggg aagaaaacat atcccatttg gagcattgct caactcgttt
      601 acgttttacg ttaaaagaca acagcaaggt aaatatgagc cagttagaaa aagtggatgg
      661 cgttatgggc gttcgccaaa atgtgcaatg ccaagtaatc attggaaacg atgttgttga
      721 agtgtatgat gaagtgaaag cgttattagg tgacaatgtt tcaaatactg aagaagcacc
      781 aaaacaaaaa caaaaattag gttcagttct attagatttt attatttcta ttttccaacc
      841 tttaattcct gcgattgcag gtggaggagt attgaagtcc ttgttgctac tagcttctat
      901 cttagggctg attagtgacc aatctcaaac ctatcagatt ttaaatttgg tcggcggggc
      961 accgctttat ttcttgccta ttctggtggc aatgactacg gctaataaat tgaaagtcaa
     1021 tcaattggtt gcagtatctg ctgtcggtgc attgatcctt cctgaaatga cagctatgtt
     1081 ggcggaaggt gctacattct tatcttttgg attggataat atagcgtatg catctcaagt
     1141 attcccagcc atcttaactg ttttatttta tgctcaactt gaaaaatggt ttacaaaagt
     1201 ttcaccaaaa ccaattcgta ttttctttgt acctatgatg agcttattga ttacagttcc
     1261 tattgctttg ttgcttctag gaccattagg ttataatgta ggaacagctt tctcttctat
     1321 cattgtgtct ttgtacaatc aatttggatg ggttgcaacc ggagtcttag cagctgtact
     1381 gccattaatg gttgtaacgg gtatgcataa agcaatgatc ccttacgctg tttcatccat
     1441 gagtgaattg ggtgcagaac ttctttatct cccggcttca ttggcacaca atatttcaga
     1501 agctggcgca tgctttgctg tcagtatcaa aacaaaagac aaaaaattga aatctacggc
     1561 tgtttctgcg ggtatatctg cattattcgg aattactgaa ccagctcttt acggggtaac
     1621 gattctgcac aaacgtgttt tatatgccgt tatgttttct agcctgatcg ggggagcatt
     1681 tgcaggaatc gttgcacttc aagcctttgc tttagtgggt cctgggattg caagtatcac
     1741 gatgttcgct gacaaagctg acccaatgaa tctggtttgg gcatttgcag tatcggggat
     1801 ttcatttgtg gttgcttttg ctgcagcgtt ggttctttat aaagataaag aagttgtcaa
     1861 tgaagttgaa actaagatgg aaacggccgt tgtttcagat gctgttcttt caagtcccgt
     1921 gaatggaaaa gtaatctcac tatcagaagt aaaagacact gttttttcta gtggtatggt
     1981 aggtgatgga gtagcaatca ttcctgaaga agggatatta gtagctcctg aagatggaga
     2041 aatcacaatg gtatttgaaa cgaagcatgc tattggttta aaaacggcta atggtgcaga
     2101 acttcttttt catattggta ttgatactgt tcagttagaa ggaaaagggt ttgaggcatt
     2161 tgttcgttct ggtgaaaaag tagccaaagg acaaaagctg attgcatttg atattgattt
     2221 aatcaaagaa gcaggattcg accccacagt tatctgtgtg gtaaccaata aggataatta
     2281 cactatccgt tcatttaacc tagaaaaatt ggtaaccaat gatagtgatc tcttagctat
     2341 cagtccgata gcttaaacac aagatagtga aaaaaaatat attgaatgaa ggaatagagg
     2401 agaatagaat aatgacaaac acaacaagtt ttccaaaagg atttttatgg ggcggcgcga
     2461 tagcagcaaa tcaagtagaa ggtgcttgga atgtagacgg taaaggtctt tcagtagcgg
     2521 atatggctac ttataaacca aatttagaca acaaagattt tgctgctcat atgcatgtca
     2581 ccctgcagtc tataaaagaa gctagtgaag acaaatctga taaatggtac ccaaaaa
//
LOCUS       DADQDV010000166         2584 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.174, whole genome shotgun sequence.
ACCESSION   DADQDV010000166 DADQDV010000000
VERSION     DADQDV010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2584
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.174"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..301
                     /locus_tag="J8S10_003073"
     CDS             <1..301
                     /locus_tag="J8S10_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HAZ9631593.1"
                     /translation="STYAKTLFRLLMQYRSTGYYVVRIEEFRSLMDIPEYYQMGNIDQ
                     KVLNPALRELKKYFNDLKVTKIKAKKGNKIAKLEFTFSSLTSDLPKISLRNWLEE"
     gene            complement(438..854)
                     /locus_tag="J8S10_003074"
     CDS             complement(438..854)
                     /locus_tag="J8S10_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631594.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     EAKLNPSNRNRPKNHQKETSQTVTSRNFDPTNFLKR"
     gene            complement(857..1141)
                     /locus_tag="J8S10_003075"
     CDS             complement(857..1141)
                     /locus_tag="J8S10_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631595.1"
                     /translation="MDILVRNIDPKFVATIDKRCQELTNKTGEKWSRNKYLKVLIESD
                     FDRQLTTYKKDQFDLLLDKFIAIQTENTQILSEYVYTNNQIIEMLIGGMI"
     gene            complement(1841..1936)
                     /locus_tag="J8S10_003076"
     CDS             complement(1841..1936)
                     /locus_tag="J8S10_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HAZ9631596.1"
                     /translation="MCFVFTNFICSLLVGLLSALFSYWLNNRNKK"
BASE COUNT          818 a          424 c          488 g          854 t
ORIGIN      
        1 ttctacgtat gcaaaaactc tattccgact gcttatgcag taccgttcta ctggttatta
       61 tgtagttcgt attgaagagt ttaggagctt aatggatatc ccagaatact atcaaatggg
      121 taacattgat caaaaagtat taaatcctgc attacgagaa ctaaaaaaat acttcaatga
      181 tcttaaagtc acaaaaataa aagcaaaaaa gggcaataaa atcgccaaat tagaatttac
      241 tttttcaagc ctaacgtcag atttgccaaa gatttctctg cgtaactggt tagaagaata
      301 aataaaaaag aactcgcccc ccttacatta agcaagtaga caagtccctt acaaccgact
      361 aagattgcta gtacattcta gcatattgta tggggcttct aaataaaaaa cagataggaa
      421 taactcctat ctgtttttta tcgttttaga aaatttgttg ggtcgaaatt tctagaagtg
      481 actgtttgac tggtttcttt ttgatgattc tttggtcgat ttcgatttga tggatttagt
      541 ttagcttcga ttttttcttt cacttcttga tatactttag aatttgtgcc aataagaacg
      601 cctgtatctt ttagatataa atcagcaaat tctgcgatga tttcagtcat gatggaaatt
      661 tcttttccca tagcatttag ttttgcctga ttgctggtag tggtcgtgtt ggtatcgggt
      721 tcataactca tacataaaaa gcgaatggct tccgagtagt tattgatatc tggatttttt
      781 tcgatgatgg aatctaaaac gtcaacatga ctagggtaca aagtaacatg tttttggaca
      841 gaagtttttc tcatggttat atcattcctc cgataagcat ttcaatgatt tgattatttg
      901 tgtagacata ctcgcttaat atttgagtat tttctgtttg gatagcaata aatttatcga
      961 gcaataaatc gaattggtct tttttgtaag tcgtaagttg acggtcaaaa tcactttcga
     1021 ttaaaacttt tagatattta tttcgactcc atttttctcc tgttttattc gtgagttctt
     1081 ggcaacgttt gtctattgtt gcaacaaact ttggatcaat attccgaact aaaatgtcca
     1141 taaaaaatct ccttttgcaa ttatgtataa tttatgtata ccatacaaat actatatttg
     1201 tatagctgtt ttttgccaaa atgctataca taagctaccc acgatggcga aaaagtgata
     1261 tcaaattttt ttctgagaaa cgtgataggc acagcctatc tacccacttt ttttagaaag
     1321 tgggtacacg tttccttatg ctctttaaaa ttcggggggg agtgctgcac gtgtaatcga
     1381 taaccaaatt taacagacga aaaattgttg gaatataaaa atatgacacc cgaaagaaaa
     1441 cgatcgttgg aaaaattaat gcaactagtg aacgaagacg gcggaatttc agacgcagct
     1501 tttgacgcat ggagcgaatt tcatggagaa tataattaag tgggtttaaa tggctctaaa
     1561 atcgcttcta agagtttttt agcttggacc aatgaaatac accaaaaact aaataaaacg
     1621 tcttaaatcg aaaaatacga gctctcagag cgactttatt tgtaaatgtt gcatataaga
     1681 aataattacg gattttagac ttttgtagga tatttttgaa ataaatattt atttctgtta
     1741 taatttgatt gcaaataagt gaacacgaaa cacacgaaat ccccagagag gtcggattct
     1801 ctggggcttt ttttgtgggc tgagtcgcct taattaagtt ttacttcttg tttcggttat
     1861 tcaaccagta actgaacaaa gcgcttaaaa gcccaacaag aagggagcaa ataaagttag
     1921 tgaacacgaa acacacctcc ttccagtcgc aagactgtcg gataggcgac aatcaattat
     1981 acaataaaaa agcaaaaata agcctaagtt ttttattgcc ttggggttgt tagggcttgc
     2041 cctgaccgcc tgtaaggcgc tttagaacga aggacatagt ttttatcgaa tcttgtctta
     2101 gaacggctta gacgagctct caggacgcca caaaggagtc cctaatgaat tatttttggc
     2161 gaaggagcct aaaggcgact gctgcaagta aaatgtgaga gcgtagcgat cactccttct
     2221 tacagcgacc atagggagct agattggcag tttaatatca tgcgcgaacc tgtttatttt
     2281 aaaaagtggg tgattttttg gcgggaaatt ttgctcgcgc gcgcgcgttt attttattta
     2341 ttttttaaag attttttaga acccttttta gggggcagtt gagccttact ctcccaacgg
     2401 atacagaagg gtactaacaa ctttttatct gagtactaac aactttttat ctgagtacta
     2461 acaacttttt atctgagtac taatatcctt ttgtataata acaaccaacc tatttacgag
     2521 ttggttgtta aaggttatta tttatttgta aggggggaag aaaggaatgg atgaaaaaac
     2581 ggaa
//
LOCUS       DADQDV010000167         2400 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.175, whole genome shotgun sequence.
ACCESSION   DADQDV010000167 DADQDV010000000
VERSION     DADQDV010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2400
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.175"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            207..2069
                     /locus_tag="J8S10_003077"
     CDS             207..2069
                     /locus_tag="J8S10_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAZ9631597.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2069..>2400
                     /locus_tag="J8S10_003078"
     CDS             2069..>2400
                     /locus_tag="J8S10_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAZ9631598.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          866 a          353 c          466 g          715 t
ORIGIN      
        1 aaaaatttga aaaagcgttt gattatttat attacgactt agtgcaataa aaaacgcttt
       61 ttaacagtac atgtagtcgt ctttataata gataaactct gtaatattag ttaaaaagct
      121 ataagttgca cttagttaag tgcaaacatt tcatattgtc gttagtttag aaaacgctta
      181 tattagcaat gtaaggagag atgataatgc agcagctaac aaaaagagaa aggcagcttt
      241 tgatttactt ggtggaaatg tctgaaccgg taacaatcaa aaagttggct gaaaaagaaa
      301 atgttagtgt tcggacgata aaatacgatc tagatgatat aagagagtgg ctgaatgagc
      361 ggaagcaagt cctatatagc aaacgtagtc agggaatttg gatgaatatt agtagctctg
      421 atcgaatcaa attaaaaagc gaattgatgg atgttaatcg ttttgaaata tttgcagatc
      481 aaagtctccg aatcaaacgt ttactaatta tgcttttagt aacaaaagaa gctattactg
      541 gaatgaaaat ggccaacgca ttagatgtca gcaaagatac gatcatgaat gatttagatg
      601 tgctggaaaa taattttctt aaggaaggat tgaccttgaa tcgtcaggcg cgaaagggtt
      661 tttggatcat aggagaagaa cgtctagttc gattaacgat tgaagagatt cttcaaaaag
      721 agttcacgga ttatgacatt tataaattaa tgtcattgtt attgaatggc ggtgagactg
      781 aatactttga aatgtattct gctactgcta cacctatcca agaggtattt aatcaagtaa
      841 tcattcgaat gcgacactta ctggaatttg aaaatctaga gaaactgaat tacgcggaat
      901 tactaaatat tctgattcga gtgacaattg ctaccgttcg cttacgcaaa gaggctacga
      961 ttggtcgtta tcaattggtt gctgaacaag aattagacaa aaacgatctt tcttatcgcg
     1021 tcatgcagca ggtctttgat tattatcagt tgccactgtt cgaggatgaa tatcattata
     1081 tctatagtga tacattcgac acgattcacc agcaagacgt catgaaacta gttgagaatg
     1141 tgatttataa agtaagtaaa gcaatcaacc attcttttta tcaagatcca caattgttga
     1201 cgaatctgta tgctcattta tccatgcgat tatcgagaaa gaaaaaattt gtcaatgaat
     1261 ataatccttt taaagaagat atcaagcaga aatacccgga attatttgat gcgatcaagc
     1321 aagcagttcg acaagaaata agtgaacaaa atattctgat caatgattct ttcgtggcat
     1381 atattgcctt acactttttg gtttcctacg aaagagaaga agatctacga agcgttagag
     1441 ccgtctacat ttgttcaaca gggttgggtg tgactagtct gatcaagcaa aagatcaatg
     1501 aagaattaaa taatatcact atcgtggcat ttgcttcagt attgaatgcg caagaaatga
     1561 ttgctaccaa agatcctgat ttggtgatta gtatttttcc aattaatggc atcgatcgtc
     1621 ctttcatcaa agtccatcca ttacccactg aacaggactt gaaaaaaatt caacaaataa
     1681 taaaaaaaat acttgcttct tccaatcagc aggaaaggca taacttgaat cttagagaaa
     1741 cgtccatcaa taaagatact ttagaagact ttagcaagga attgattttg aaagcttata
     1801 cgatttatga acgtttactt gtcattttgg aagcagaatt gatccaagaa tatcgagaag
     1861 cttttttgct tcatgtattc ttaatggttc atcgtatcac atttgatcaa caatatatgg
     1921 cagaaggtcg tcaagtagac cagattattt tagacaaagg aacactggta ggaaaaatcg
     1981 aagcagtttt tgcagaaaat aatttaggaa tcaatcagtc agaaatcagt gcattattct
     2041 catatataaa agaaggagcg tcaagttagt gaaaatgtca gacgaggctt taaaaattat
     2101 cgaggaaagt caaaatcggg aaaagttaaa acaagtgatt gatctaattg aagagcgatt
     2161 agtagaacat gctattgtac caaccgagtt gcagtggacc attctaatta atcacttgaa
     2221 tgagatgctg aaacgttctc aaagaaagga aacgattccc gtagtcgatc gggatttgtt
     2281 caaagaagta tccaaagaag ccataactat ttctgatgaa atagttagaa gtatcggtaa
     2341 tttaaccgat gatgaaatat atgttttgtc gattcatttt gaaacagcaa aaaataatta
//
LOCUS       DADQDV010000168         2262 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.176, whole genome shotgun sequence.
ACCESSION   DADQDV010000168 DADQDV010000000
VERSION     DADQDV010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2262)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2262)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2262
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.176"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(151..2148)
                     /locus_tag="J8S10_003079"
     CDS             complement(151..2148)
                     /locus_tag="J8S10_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HAZ9631599.1"
                     /translation="MIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKA
                     LVTNKANQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHL
                     KEATKRLSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVY
                     IKNSGVTDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADE
                     AEKYLAKGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGS
                     NLMLSMNAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHE
                     QGSKEITENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKS
                     SVFNRSGQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRD
                     SFKEFGLGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYT
                     PIQLAQYASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMA
                     ILREGFHQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGP
                     TDNPEIAISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
BASE COUNT          576 a          505 c          411 g          770 t
ORIGIN      
        1 aatttttgtc acaacctttt ttgccgagta aacggtgttc aaaagccagt ttctcggtat
       61 gaagtcaaat ttaagcaaaa atgtgagaag ctattttcac aaaatttttc ttcatactcg
      121 aaactaagcg gctttttcac gacctctttt ttattttgcc atgaacatat cataatacgc
      181 gtccattatt tctttagcaa tcgtcaagtt tatgtggtct tgttcgtcta ataagttcgg
      241 caagacaaca ctgatggcaa tttccggatt gtctgttggt ccgtatgcca cgatattact
      301 attgactgtc gcaatatctg gatgaccttc cgcaaccgtt tctgcagtcc ctgtttttgc
      361 ggaaaggtcc attttcgcac tggctaatgg tttggctgtt gtgtaaggat cggtaccatg
      421 gacaacttgg tggaatcctt cacggaggat cgccatattt tctgcagaaa tattgaccgt
      481 attttctact gttgtgccaa tttctttctt cacttcaccc aagtttccat tttcgtcatt
      541 gccatagatc gctttgacta ggtgcggctg tactcgtttc ccgccattag cgactgttga
      601 agcatattga gctaattgga ttggtgtata tgtgtcaaac tgtccaaatg ccaaatcggt
      661 aaagttacct ggagcatacc attctttgcc attatccgca ttgaacttct tcatataatc
      721 aacagaacgt gagatcccag gagattcatt cggcaaatcg atcccagtcg ttgtaccaag
      781 accaaactct ttgaaagagt ctctcaattg ctgataagct ttagcttctt catctaaact
      841 aggtagtccc attccaggtg tatagtctag tcctaacatc tttaacgcca ctttgatcat
      901 atacgtatta gaagacaatt ccgatgcttt gactgcatca agagcaactt gtccgcttcg
      961 attaaagaca gagctttttt ctgaagcacc ttgcagacga atcggctcat caatcaaaac
     1021 ttgatttccg ctgatcgcgt tacttgccca gcctgctgtc aaagtaccag ccttgactac
     1081 agaccctgga tcaaaggcgc tagtaatcgt gcctaaagca ttctcggtga tttctttgga
     1141 accttgttca tgactgaaac cagtcattgc tagcacttct cctgtctgag gattcatagc
     1201 cactgcataa gcaccaggcg aatactgtgc tttgccgttg ttgatcaatg tttgataatt
     1261 ccttttcaaa atttcttcta cttttgattg gaattctgca ttcatagata acattaaatt
     1321 agaacctttt tccccagaga agatttcttt ttgattcgaa acatttcctt cattatcaag
     1381 ggaaacttca tattgggttt tggttccttg caggacatct tcatattgtt tttccaaata
     1441 actttgtcct acacggtcat tccgagaata accttttgct aggtatttct ctgcttcatc
     1501 tgctggaagt ccttgctttt cagtcgtcac actgccaaga atacttttca gtgaacttgc
     1561 tgcattatat tctcgtgtcc agtctgtgcc agtcgaaact cctggaagtt cagaagcgcg
     1621 ttctgccaca acagctaact cttgatcagt aacaccagag tttttgatat agacagtgtt
     1681 taattcatat gcactattca tccgtttaaa gatggtagca atttttaatt gctcctcgtt
     1741 taaattaatc tcatcagctg tgactttatt gaccatcgca ctatattgtt cgctgttccc
     1801 taattgcttt tcttttgccg aaagtctttt tgtggcttct ttcaaatgtt tgggatcagc
     1861 cagccaaaaa tcttttttat ctctatctgt cagattttca tctaccggaa catcgatcag
     1921 cgagttcagc ttcgttgcga tttcaagcaa atctttagcc gtaacttgtg ttcctctcgt
     1981 atatgtgatg gcctgattcg ctttattcgt aactaaagct tttcctgtgg agtcgtagat
     2041 cattccgcga ggagtacttt cttggaccgt aatcgtagaa gtagacttca ctcgcgcctc
     2101 catctcttcg ccgttcacga tctgcaaata acccaatcta gcaatcaacg caacaaataa
     2161 cgtaaatata atgaaaaaaa gaaaatttaa gcgaaaagga acatgggacc ggcgaaacgt
     2221 tttgttctta ggttcttgtg caccttttct tattttttct aa
//
LOCUS       DADQDV010000169         2247 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.177, whole genome shotgun sequence.
ACCESSION   DADQDV010000169 DADQDV010000000
VERSION     DADQDV010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2247)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2247)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2247
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.177"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..1240
                     /locus_tag="J8S10_003080"
     CDS             <1..1240
                     /locus_tag="J8S10_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAZ9631600.1"
                     /translation="RGVDFYHHYKEDLALFAEMGFKTLRLSIAWTRLFPTGEELEPNE
                     KGVAFYENVFKEMQRLGIEPIVTLSHYEMPLALAVKYNGWVERRVIDDFVRFANVCFD
                     RFGKYVKYWLTFNEIDSIHRHPFTTAGIIQEKSAEGQEAQDIYQALHHQFVASALVTK
                     DAHEKIPGSQVGCMLTKLMTYPLTCAPEDVELTLKKNLENNFYADVQVKGEYPALIEK
                     DLENRGIQIKMEDEDREILKKHTVDFVSFSYYMSMAESADPNAERTPGNTVLGVKNPH
                     LPSTDWGWQIDPKGLKISLIELYDRYQVPLMIVENGMGAVDQVVDGKIHDPYRIDYFK
                     AHFQQMKEAIDEGVDLIAYTSWGPIDLVSAGTSQMSKRYGFIYVDADDEGNGTYNRLK
                     KDSFNWYKEVIETNGASLFE"
     gene            1277..2119
                     /locus_tag="J8S10_003081"
     CDS             1277..2119
                     /locus_tag="J8S10_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAZ9631601.1"
                     /translation="MISIKKVLNSSVVLVEENGKEMIALGKGIGFGQKAGDEISGDKV
                     DKIFLPFEEKKSSQLLELVEEIPIEFFEITRTIVFEAEKGLDKKLNPGVYLTLTDHLH
                     FAVERAQKGVNIANRLYWEIKIYYPKEFQIGKYALTLLNEQYGIDLPKEEASNIAFHL
                     INAQSEDPDSGAGFKYAKMIGGIVNLVRYSLQKDIDTNSIHYARFITHVRFFVERYYS
                     DALLDDGEEEFYNQMWILYPSAMESAAKIKDYIEKVYHKTIPNDEVVYLGVHINRLMK
                     HANG"
BASE COUNT          760 a          358 c          485 g          644 t
ORIGIN      
        1 aaggggcgtt gatttttatc atcactataa agaagattta gctttatttg ccgaaatggg
       61 ctttaaaacc ttgcgcctct ctattgcttg gactcgcttg ttccctacag gagaagagct
      121 ggaaccgaat gaaaaagggg ttgcatttta tgaaaacgtc tttaaagaaa tgcaacgttt
      181 aggaattgag ccgattgtga cactatctca ttatgaaatg ccattagctt tagcagttaa
      241 atataatggc tgggtggagc gtcgagtaat tgatgatttt gttcgcttcg ctaacgtttg
      301 ttttgatcgc ttcggcaaat acgtaaaata ttggctgaca tttaatgaga tagacagcat
      361 ccaccgtcat ccatttacaa cagctggaat tatccaagag aaaagcgcag aaggtcaaga
      421 agctcaagat atctatcaag cattgcatca tcaatttgtt gcgagtgcgt tagtgacaaa
      481 agatgctcat gaaaaaattc caggaagcca agttggttgt atgttaacga aattgatgac
      541 ttatccatta acttgcgcac cagaagacgt tgagctgacc ttgaaaaaga acttagaaaa
      601 taatttttat gcagatgttc aagttaaggg agaatatcct gctctaatcg aaaaggattt
      661 ggaaaatcgg ggaattcaga ttaaaatgga agatgaagat cgagaaattt taaagaaaca
      721 taccgtagat tttgtttctt tcagctatta catgtccatg gcagaatcag ctgatccaaa
      781 cgcagaacgc acaccgggaa atactgtttt aggggttaag aatcctcatt tgccttcaac
      841 agattggggc tggcaaatcg atccaaaagg tttgaaaatt tcgttgatcg aactttatga
      901 tcgttaccaa gtaccgttga tgattgtgga aaatggtatg ggagcagtcg atcaggtagt
      961 agatggtaaa atccatgatc cgtaccgcat cgactacttt aaagcacact tccaacaaat
     1021 gaaagaagca atcgatgaag gtgtagattt gatagcttat actagctggg gaccaattga
     1081 tttagttagt gcaggaactt ctcaaatgtc taaacgatat ggatttattt atgtggatgc
     1141 agacgatgaa ggaaatggga catataaccg cttgaaaaag gattcgttca actggtacaa
     1201 agaagtgatc gaaacaaacg gtgcatcctt attcgagtag tctcgatctt tttaagcagc
     1261 gataggggga taatgagtga tttcaataaa aaaagtattg aattcaagtg tggtacttgt
     1321 tgaagaaaat ggcaaagaaa tgattgcatt aggtaaaggg ataggctttg gacagaaagc
     1381 tggggatgaa atatcaggag ataaagtaga taaaatattt ctgccttttg aagaaaagaa
     1441 atcttcacaa ctattagagt tagttgaaga aatacctatt gaattttttg aaatcactcg
     1501 tactatcgtt tttgaagcag aaaaaggatt agataaaaaa ctgaatcctg gagtctattt
     1561 aaccttaaca gaccacctgc attttgcagt tgaacgcgca caaaaagggg taaatattgc
     1621 aaaccgtttg tactgggaaa taaaaatcta ctatcccaaa gaatttcaaa ttgggaagta
     1681 cgcactcacc cttttgaacg agcaatatgg aattgatctt cctaaagagg aagcctcaaa
     1741 cattgctttc catttgatca atgcacaatc ggaagatcct gatagcggcg ctggattcaa
     1801 gtatgcaaaa atgatcggcg ggatcgtcaa tttggtccgg tattcgttgc agaaagatat
     1861 cgatactaat tcgatccatt atgcccgctt cattacacat gtacgtttct ttgtagaaag
     1921 atattattct gatgctttgt tggatgatgg tgaggaagaa ttctacaatc aaatgtggat
     1981 cttatacccg tctgccatgg aaagcgcagc taagatcaaa gactacattg aaaaagttta
     2041 tcataaaaca attccgaacg atgaagttgt atacctaggt gtccacatca atcggttgat
     2101 gaaacatgct aatgggtgag cgctcagtaa tactattgat gcttttaaaa tctttagaga
     2161 tggattatag taaaaacaag gtgatttcca gctgtttgtt atctataaga gacatttaaa
     2221 aaggattaac gtaagataat aaaaaat
//
LOCUS       DADQDV010000170         2125 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.179, whole genome shotgun sequence.
ACCESSION   DADQDV010000170 DADQDV010000000
VERSION     DADQDV010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2125)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2125)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2125
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.179"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..425)
                     /locus_tag="J8S10_003082"
     CDS             complement(<1..425)
                     /locus_tag="J8S10_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HAZ9631602.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQIP"
     gene            complement(534..1565)
                     /locus_tag="J8S10_003083"
     CDS             complement(534..1565)
                     /locus_tag="J8S10_003083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAZ9631603.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
BASE COUNT          666 a          340 c          363 g          756 t
ORIGIN      
        1 ggaatctgtt ttgattttgt tccatttgaa atttctctca ctcgcttttt tgtctcatca
       61 tcaaataaaa tgaaagggtc ttctaaacga tcgataaata cttccattgt tgttgttggt
      121 agatgataag aagtcatgac aggcactgca ccaaggtaag acacagaaac agctagaagg
      181 tatgtgtcaa aagcggaact cttataaata ataactttgt ctccggattt cactccaaga
      241 tgagccaatt gataagcccg tttcaacaca ctttcgcagc attttttgta agttgtttca
      301 agtcctaatt ctgggaaagc tgaaagtggc tcatcaaaga taatcggggt ctcggaaaag
      361 ttagctgcag cttcttgaaa attcgtaaat aagttcaaag gggaatacgt tatggtctcc
      421 atcattcaca ctccattatc ttttgttaag taatatacaa attcaagata atcgtaacat
      481 aatcctttat ataataacat agtttattgt gaaaaaaaga tcatacattt gttttatatg
      541 gaagaaaccc gaacgaatgc cgctaattcg tgataagaaa aatcaaccat cttttcccag
      601 atatcttgaa aagaatggga tgagaggtat cgattaccac ataaataatt taccgcgtca
      661 gcatcatcta aatatagttc tgcataataa cgatatgttt ttctgcatag ttctggcgat
      721 acgtttttat atactgtaat tttgctcaaa atttggcgaa tagtccgagg agaaatttgc
      781 tgatcatgtg aggaacgaaa aacaaaagaa ttttcgtccg tattttgtgc tgttaactta
      841 aaatagttct ccagaaatgg catcgcttct tttggtattg gtactttatt cagtctgttt
      901 tcttttctat tcagattaag aatctgcttg gtcaaagata catctttacg tttaagttct
      961 actacttcat ggatctttaa tccgcaatac agaagaatgg cagtaattgc aaggttcctc
     1021 ggtctattct tttcttcaaa gctagcttct ctgcttgttt gaaagccttc aatcgggata
     1081 aacaaatgct caaaatcttt gaaaagttct gcatcgatat atcgcggagc tgctttggtt
     1141 gtttccggta aacttgtacc caaaagagaa atctcttctt caatcagtcc tttttgatac
     1201 aaaaatcgta aaaaatgatt taatgaatat tgcttccttg aaatcccgta atagctattt
     1261 tcaaacaatt gctccgtttc ttggttcgct gtagtttgga acgaacgagt atgtcgatag
     1321 attttagcta agaaattctg ataatcttgt ttttctaaat ggataatcag ctgatcatcc
     1381 acttcttcag aaaatacttt tctcaaataa tcagtaaaca gatgaaaatc ttttgcgtat
     1441 tcatagcgac tgcctaatga aagggaagaa cgattttctt ctaaaaactg ttgaaagacg
     1501 gaagggagca agtgtgtacg ttgctttaac ttttcttgca gttgttttct agttttgctg
     1561 tccattacaa attccctcca atagtgttca ttttctatat tttaccgcat ttcatcaaat
     1621 gaagatagac agtttgtctt gatcttagga agcaaatttt taactaagta ctagctaaaa
     1681 gatatgaagt aagaagatac atttttagtt attttattag tgcagtcatt cttttgatct
     1741 tttaattgat ttatcctctt tttagctatg tggttacttc atgagcaatg aaatggattt
     1801 ggttcgttct aatggcagga ggctctttct tttatttccg aaaaattaga aaacattttt
     1861 tcagaatcga ttggctctcc atttattcaa taatggtttg tctaacgata ttgttgggat
     1921 aattcttaaa gaagtattag aaatagttgg tacttcatta ctttacatga agatttattc
     1981 tatggtagga gcaattatat tgagaattaa tcctttttta tataagttgt ttgcttattg
     2041 atggattgga taaattaaac catcacaacg agtggaaatt atatgaaatt tttcataaaa
     2101 attcatatag aaacaaatga cattt
//
LOCUS       DADQDV010000171         2056 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.180, whole genome shotgun sequence.
ACCESSION   DADQDV010000171 DADQDV010000000
VERSION     DADQDV010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2056
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.180"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            493..714
                     /locus_tag="J8S10_003084"
     CDS             493..714
                     /locus_tag="J8S10_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631604.1"
                     /translation="MRVIKSEKFTLAEIMTTSELAQELDYNQAYVLRLAKEHLTEGKE
                     YRSAGRRNYLFSPEALKKLEKVITTKEGE"
     gene            715..972
                     /locus_tag="J8S10_003085"
     CDS             715..972
                     /locus_tag="J8S10_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631605.1"
                     /translation="MPKETTINVEQLEKLLESYSNDFIELTGGKVEETTDLFDLLLTN
                     ILELNSEEQKEHKGKLIAPSYRKVAKSAVPTGFLTKQPYIF"
     gene            complement(1108..1710)
                     /locus_tag="J8S10_003086"
     CDS             complement(1108..1710)
                     /locus_tag="J8S10_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HAZ9631606.1"
                     /translation="MTSRKTKDERTRNWTFVVYPESAPENWREFLDELHVPWVESPLH
                     DKDVNPDGELKKPHWHVLIMFSGKKTYDQIREITQKLRSPNPQKCANAKGMVRYFAHM
                     DNPEKFQYAKSDIIAHGGAEIASYLSVTSAERYELIREMMSFVDSKNITEIKDLIDYA
                     MSERFDDWFPLLCDNSAYIIGQYIKSNRHGGSVNSKINKG"
     gene            complement(1777..1932)
                     /locus_tag="J8S10_003087"
     CDS             complement(1777..1932)
                     /locus_tag="J8S10_003087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010001600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAZ9631607.1"
                     /translation="MISNEKKRVVVTLTKEVADNLDKIAKQMGLSKSGLITIWVNANG
                     KENEQKK"
BASE COUNT          678 a          462 c          314 g          602 t
ORIGIN      
        1 aaaaaaaaac gctgaaaccc ttgggagagt aaggctaaac agctatcgac caatgaccaa
       61 tgaccaataa ggggggtgtc gtagtccccc cctcctccgc ccaattcata aacaccaaaa
      121 ccaaaaaaca aacctcaggg ctccgccccg aaccccgacc tccttctacc gaaatatatg
      181 caggcgccac gcttactatt tcgttcagct atcggctttt gcaatctaac acgaccgttt
      241 cgctaccagt cgccttacag gctccattct cgcttctctt acgtgtttta acgattgcgc
      301 cgataactaa acgaaataga cgctaaatcg cttaaaacgc aaaatagacc ctttttagag
      361 cattgatttt ttctactagt catttcgata atataaaatt gaccacaaca cagaaaactt
      421 atattataag cttatgtcgt aagtccgacg tactcacgta atatagacgg acgttaaatg
      481 gaaggagcat aaatgagagt gataaaatca gaaaaattca ctttggccga aattatgacg
      541 accagcgaac ttgcacaaga acttgattac aaccaagctt acgttttgcg cttagcgaaa
      601 gaacatctga ctgaaggaaa agaatatcgc tctgccggta gaagaaacta tcttttcagc
      661 ccagaagccc ttaaaaaact agaaaaagtc ataaccacca aagaaggtga gtaaatgcct
      721 aaagaaacaa ctatcaacgt tgaacaacta gaaaaattgc tagaatcata ttccaatgat
      781 tttatcgaat tgaccggcgg aaaagtcgaa gaaaccaccg acctctttga cctacttctc
      841 acaaatattc tggaattaaa ctctgaagaa caaaaagagc ataagggaaa actgatagca
      901 ccttcctaca ggaaggtggc taagtcggct gtgccaactg gttttcttac aaaacaacct
      961 tatatttttt gatatcacaa aaaaatccat tttggaccta ttttcggtca taatatagta
     1021 cctacttttg gtcatagttt cgtccgtagt tttggtcata gtgactaaga ctttcacgca
     1081 caaaaaaaga gctgaaatta acagctctta tcctttattt atttttgaat ttacacttcc
     1141 accatgacga ttcgatttta tatattgccc gataatataa gctgaattat cacaaagaag
     1201 cggaaaccaa tcatcaaatc tttctgacat tgcatagtca attaaatctt tgatttcagt
     1261 gatattctta gaatcaacaa acgacatcat ctctctaatc aactcatatc gttctgcact
     1321 cgttactgac aaataactag caatttctgc accaccatga gcgataatat cacttttagc
     1381 atattgaaat ttttctggat tatccatatg agcaaaatat cgcaccatac cttttgcatt
     1441 agcacatttt tgcgggtttg gagaccgaag cttttgagtt atctcacgta tttgatcata
     1501 cgtcttttta ccgctaaaca ttatcaaaac atgccaatga ggctttttca attcaccgtc
     1561 aggattcaca tctttatcat gaagtggact ctcaacccaa ggaacatgta actcatctaa
     1621 aaactccctc caattttcag gagccgattc aggatagact acaaacgtcc aattccttgt
     1681 gcgttcatct ttagtttttc tactcgtcat gctataatta ccttaattga acaacagtct
     1741 aacagcaaaa gcagtgcgcc aacactaatg cttttgctat tttttttgct cattttcctt
     1801 tccgttagca ttaacccaaa ttgtaataag accagactta ctaagaccca tttgtttcgc
     1861 aattttatca agattatctg ccacttcctt agtaagcgtt acaacgactc tctttttttc
     1921 attactgatc ataattcgta tcctccaacg actttttctt aaaaaccata gtaacaaaaa
     1981 agtaactaag gtgcaacagt ttagatacta attagcgaat aataggcctt aaacccttgg
     2041 cattactgat tttgtc
//
LOCUS       DADQDV010000172         2055 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.181, whole genome shotgun sequence.
ACCESSION   DADQDV010000172 DADQDV010000000
VERSION     DADQDV010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2055)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2055)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2055
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.181"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..562)
                     /locus_tag="J8S10_003088"
     CDS             complement(<1..562)
                     /locus_tag="J8S10_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF443 family protein"
                     /protein_id="HAZ9631608.1"
                     /translation="METVRLWIFMKNFRSALRYVILESKSGYYLIDTDHYTFWGGYLF
                     PIFNWIIPHKVMKINLPAEEINRLILNKDLQRKREKEHSNVAWIGPAFAVVTSSIVGP
                     MLESIYSDFSIGIRYLFVTLSIAVLLCIKGYVSKKNKDILTLIGVNNLSSTKIILFPE
                     SIKEGSRLLIIFIMLILFSVLFGVMFI"
     gene            complement(749..1399)
                     /locus_tag="J8S10_003089"
     CDS             complement(749..1399)
                     /locus_tag="J8S10_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631609.1"
                     /translation="MFIKGGQKMCFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLR
                     AGLITFISIVGFFLFTVIVFIWRTTAPPLPEITYGEFPFSLEYEIDEERILIEDTVIA
                     EFIGSFRGNVTTQPRRSWSIKLLNNSGELKAFHYEFLIIESEDVTITLSSGSAGYFMN
                     DGGSKPQLTVRDRIAGFMHFSHYDLEEARKILAEYGITLINWEYAPPIRNFFNDYY"
BASE COUNT          722 a          406 c          252 g          675 t
ORIGIN      
        1 ctataaacat caccccaaat aaaacagaaa acagtataag cattataaaa attatcaaca
       61 accttgatcc ttcttttata gattcaggaa acagtataat tttagtacta gataaattgt
      121 ttacaccgat tagtgttaaa atatctttat tcttcttgct aacataaccc tttatgcaca
      181 aaagaacagc tatacttaaa gtaacaaata aataacgtat tccaatagaa aaatcactat
      241 aaatactctc tagcatagga ccgacaattg aagaagtcac tactgcaaat gctggaccta
      301 tccaagcaac attagaatgt tctttctctc ttttcctttg taaatctttg ttgagtatta
      361 atctatttat ttcttctgca ggcaagttaa ttttcataac cttatggggg attatccaat
      421 taaaaatcgg aaaaaggtag cctccccaaa aagtatagtg atctgtgtca atcagataat
      481 aacctgattt tgattccaga ataacatatc tcaaagccga acgaaaattt ttcatgaata
      541 tccataatct cactgtttcc acacctaatt cctccaattc caattaaatg gatttatagc
      601 atcaccaatt atgttaactg cctgaccaac ctcattgata aaattggcac cactatccca
      661 tgcttcaaca atgctatata tctatcaaac aaaaaatgga aaactaaata ctcgcgcaca
      721 taaattttac attctgtttt ttataagact aataataatc attgaaaaaa tttcttatcg
      781 gtggcgcata ttcccaattg attaatgtga tcccatattc tgcaagtatt ttacgagctt
      841 cttctaagtc atagtgagaa aaatgcataa aacctgcaat acgatcacgg actgtgagct
      901 gtggcttgct tccaccatca ttcataaaat atccagcaga gccactactt aaagtgattg
      961 ttacatcttc actttctatt attaagaatt cataatgaaa tgctttcaac tctccactat
     1021 tatttaaaag ttttatactc caacttcgtc taggttgagt tgtcacattc cctctaaaac
     1081 ttcctataaa ttctgcaatc accgtatctt caatcaaaat tctttcctca tctatttcat
     1141 attcaagact aaacggaaat tctccatatg taatctctgg caatggtggt gctgtagttc
     1201 tccaaataaa tacaataact gtgaatagaa aaaatccaac gatcgatata aatgttatga
     1261 gacctgctcg aagtaaaacc cgatataata aaaatgctgt atttcgcttt gctatatcta
     1321 gaaaaataaa aagtactgca atcataatga tagtaaaagt tgtaaaaaag cacatttttt
     1381 gccctccctt tataaacatc gattctcaaa ttctaaacca aatcttgata gttcaagttc
     1441 aggtataacg tataccaacc atacatccca attactattt atgaacttat gattatcact
     1501 gaataaatca ctccatcccc ttgttaaaac ttctacatta attacacctg gttgttttcg
     1561 actagctaat ccaatgaact tatcaaccat ccttatccac caaccacgag aatcttgacc
     1621 agaagtaaga aaaacagttc tcaaggttga tcgagcagtt ccttccagtt tttaattaat
     1681 ctccagttat agataaatac ttgatcctat ctatatcagg acttctatat taagcaaaag
     1741 tttatgtata aaactaaaat cttcattcag ttgtctcccc gctttttata cgattgtatt
     1801 aaaaaacaat agaagccttt caacattatg ttactccagt aaagttggaa ttatagtttg
     1861 acggaagaaa agcaagtata gcttttaaaa aaaactgata cattcgcatc tcctgcttca
     1921 tgtatcagtt ttttctggtt ctataatatt ttgtgttggt ggaaaatcga aagcgatttt
     1981 ctactaacac ttttttcttc gtttcaactc aaaaagagac tcacttttgg taaaatttag
     2041 tcgaccaaaa cgtca
//
LOCUS       DADQDV010000173         2003 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.182, whole genome shotgun sequence.
ACCESSION   DADQDV010000173 DADQDV010000000
VERSION     DADQDV010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2003
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.182"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..378
                     /locus_tag="J8S10_003090"
     CDS             <1..378
                     /locus_tag="J8S10_003090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HAZ9631610.1"
                     /translation="KNVSTEDFFNYCRLEESGVTVTSGTDLPLFITDIPESIIRAVFR
                     RFPEGEEVWEKETSFTTTELLKSFTSNSFKVNGLSEYGEIKVGKSASLAVFSEDLCTD
                     DWQKVMAAEVIATYLDGDLVYKK"
     gene            426..1826
                     /gene="yfcC"
                     /locus_tag="J8S10_003091"
     CDS             426..1826
                     /gene="yfcC"
                     /locus_tag="J8S10_003091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HAZ9631611.1"
                     /translation="METMKRKFTFPHSYTLIFILIILAAILTWIIPSGQFETVVENVA
                     GMEKTTVVPGTYHQIDKADYGQGFSSILMAPAEGIISAVEVVAFVLIVGGAFGIILKT
                     GAIDRGLFTLAKVLGDKGILVIPMSMILFSLGGSTFGMSEEVIPLFAVFISLMFSLGY
                     DSMTAILILFLSTQAGYVGSTINPFNVLIAQGVAGVYGNPLLWFRMLSWIVITGISIV
                     FTMLYASRVKKNPLSSIVYESDLKVKHKFQNFDTEKEFSTQDKLIIAGFIVGLGIMIW
                     GIISKGWYMVEISALFLGLGLFAGGIARFSQKEIAEAFVEGCSDFAYAAVIIGLARGV
                     LVILEGGMIIDTILNSLANLLGGLPKFLFTTILLISQVIVSFFVPSSSGAAALTMPVM
                     APLGDLMNVSRDVVVLSNQFGNGLMNIISPTSGVLLAGLAIAEINFSKWFKVGFKIFA
                     ILTLVSAVLLYIATLF"
     gene            1859..>2003
                     /locus_tag="J8S10_003092"
     CDS             1859..>2003
                     /locus_tag="J8S10_003092"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAZ9631612.1"
                     /translation="MIKINQLAGMNIHYLFYSLKEFFAYQQKIGISSVELWGGAPHFF
                     IDAF"
BASE COUNT          555 a          339 c          432 g          677 t
ORIGIN      
        1 aaaaatgttt ccacagagga cttctttaat tattgtcgat tagaggaaag tggtgtaaca
       61 gtcactagcg gtacagattt accgctgttt attactgata ttcctgaatc gattataaga
      121 gcagtattcc gtcgttttcc tgaaggagaa gaagtctggg agaaagaaac aagcttcacg
      181 acaaccgagc tgctgaaaag ttttacaagc aacagcttca aagtaaatgg tttatcggag
      241 tacggagaaa taaaagtagg gaaaagcgcc agcttagctg ttttcagcga ggacctctgt
      301 actgatgact ggcaaaaagt gatggctgcg gaagttatcg ctacctatct tgatggtgac
      361 ttagtttaca agaaataatg cttttcgata taacgttata aaacgaatta aagagaggtt
      421 aaaaaatgga aacaatgaaa agaaaattca ccttcccaca tagttataca ttgattttta
      481 tcttaattat tttggctgca attttaactt ggataattcc tagtggtcag tttgagacag
      541 ttgttgaaaa cgtcgcaggt atggaaaaaa caacggttgt tccgggaacc tatcaccaaa
      601 tcgataaggc agattatgga caaggttttt cctctatact aatggcacca gctgaaggga
      661 ttatttcagc tgttgaggtt gttgcttttg ttctcatcgt tggtggtgcc ttcgggatta
      721 tcctaaaaac gggagccatc gatcgagggc tgtttacctt agcaaaagtt ctgggagaca
      781 aggggatctt agttattccg atgtcgatga ttctattcag cttaggagga tcaacctttg
      841 gcatgagcga ggaagtcatt cccttatttg cggtgtttat ttctctgatg ttttctcttg
      901 gctatgattc catgactgcg atcttgattc tatttttaag tacacaagcg ggatatgttg
      961 ggtcgacgat taatcccttc aacgttttaa tcgcacaggg agtagctggc gtttacggaa
     1021 atcccctgct ttggtttcgg atgctatcct ggattgtcat tactgggatt tcaattgttt
     1081 tcaccatgct ttatgctagc agagtcaaaa agaatccact gtcctctatt gtttatgaga
     1141 gtgatttaaa ggttaagcat aagtttcaaa attttgacac tgaaaaagag ttttcaacac
     1201 aagataaact aattatcgcc ggttttatcg taggtttagg aatcatgatt tggggtatca
     1261 tttccaaggg atggtatatg gttgaaattt ctgcactatt cttaggatta ggtctttttg
     1321 ctgggggcat cgctagattt tctcaaaagg aaattgctga agcttttgtc gaaggctgtt
     1381 cagatttcgc ctatgctgct gtaatcattg ggctagctag aggagtcttg gtaatcttgg
     1441 aaggtggaat gattattgac actattctaa acagcttggc taacctttta ggtggtcttc
     1501 caaaattcct gttcactacg attctactca tttctcaagt aattgtttcc ttttttgttc
     1561 catcctcctc aggagctgcg gcattaacga tgccggttat ggcaccattg ggtgatctaa
     1621 tgaatgtaag tcgtgatgtt gttgttctaa gtaaccagtt tggaaatggt ttaatgaata
     1681 ttatctcccc aactagtggt gtattactgg caggattagc catcgcagag attaatttct
     1741 ctaaatggtt taaggttggc ttcaaaatat ttgccatctt aacccttgtt tctgctgttt
     1801 tgttatacat tgctacactc ttttagtctt aatcatccat taataggagg caatagttat
     1861 gattaaaata aatcaattag caggaatgaa tatccactat ttattttatt ctctcaaaga
     1921 atttttcgct tatcaacaga aaattggtat ttcttctgtt gaactttggg gaggtgctcc
     1981 gcattttttc atagatgctt tta
//
LOCUS       DADQDV010000174         1964 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.183, whole genome shotgun sequence.
ACCESSION   DADQDV010000174 DADQDV010000000
VERSION     DADQDV010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1964)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1964)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1964
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.183"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            116..1582
                     /locus_tag="J8S10_003093"
     CDS             116..1582
                     /locus_tag="J8S10_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAZ9631613.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
BASE COUNT          611 a          335 c          401 g          617 t
ORIGIN      
        1 cgatgtgtat taaataaaag aatacacaca taaaataaca ctgtcttgta agtttgttaa
       61 aaattgaata tgattacatc tggataacaa atttttatca taaaggagag aacgaatgaa
      121 caacaaacaa ttacgctggt ttactgttgc gttaattgca tttaacatgg tttggggcat
      181 ggggaatgta gttaataact atgctcagca aggagtatca gttgtcacct cttggctatt
      241 gattttggcc atttatttta ttccatacgc attgatcgtt ggacaattag gatcagcctt
      301 caaggatagt aaaggaggcg tcagttcatg ggtcgaaaat acgacatcta ataaacgact
      361 ggcatactat gccgcttgga cttactgggt cgtccatatt ccttatttgg cacaaaagcc
      421 tcaagcaatt ctgattgctg gtggttgggc agtccaagga aatggaaata tcgtaaatac
      481 gatgtcagta caaatggtag cagttatttc acttattata tttcttgcct ttttatattt
      541 atcaacaaaa ggactttcta ctttgaaagt gattggcgga ctggccggaa cagcgatgtt
      601 cgtcatgtcg atcttattta ttcttttagc tgtaacggca ccgttcatca atccaacgat
      661 ggaatttgcc acaccacata tgaatcaagt gaaaacatat attccaacat ttgatttcag
      721 ttatttcaca accgtttcga tgctagtatt tgcagttgga ggggcggaaa aaatatcccc
      781 ttatgtcaac tctacaagaa atcctgcaaa ggaatttcct aaagggatga tcttcttagc
      841 agcaatggta gggatttgtg ctgtattagg ctcagtcgca atgggtatgc tgtttgctag
      901 tgataatatt cctaaagact tgatggcaaa tggggcatac agtgcttttc aaattttagg
      961 taattactat ggtatcggta actcattgat gatcatttac gcattgacaa acatgattgg
     1021 acaaatctcc gcattagcct tttcaattga tgcaccacta aaaatcttgt tagcagatgc
     1081 ggatccagaa tttgtaccaa actggctacg taaacgtaat cgtaaaggta cattggtgaa
     1141 tggttatctt ctgacaggta tactagtagg aatcattatt ttgttgccga tttttggtat
     1201 caaagatatg aatgaattag taaaatggtt gacgaacttg aactcagttg tcatgccaat
     1261 gcgttaccta tgggtgttct tggcatatat gatgttgaat aaagcttata agaaattcaa
     1321 ttctgaatat aaatttgtta aaaatccaaa aatcggtttt atctttggtg cttggtgctt
     1381 tgccttcact gcgtttgcat gtatcctagg aatggtgcca aaagtagatt atactgctga
     1441 tcctaaagca tggtggttcc aattatttac gaatatcatc acaccaatcg tcttgatctt
     1501 attaggtatg atcttgccag caattgctcg tcgagacaaa aacaaagaaa tcactgaacc
     1561 agaaacagtg gttcagcctt aaaatagaaa tacttgttac aagaggttgt gacagaagtg
     1621 gtcagcttca agaaataaga aggaatttac gaaaattgct tctcaaattt ttgtgaagtt
     1681 tcggcttgtt tttcgaagaa gctacttctg gaacaccgtg aatcagaggt tgtgaaaaag
     1741 ctgtcctgca tcaagtaata agaacagcca aacaaaaata gcccctcata tttttcgttt
     1801 ggctgggctt attaccgcag atgcaagctt tggaacaccg tttaaggaag aggttgtaaa
     1861 atcagcgatt tgacctgagt attagagaaa caaacggaaa aatagctcct catattttgc
     1921 cgctttttga gctaatgctg aaggtcagct gattgaacac catt
//
LOCUS       DADQDV010000175         1963 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.184, whole genome shotgun sequence.
ACCESSION   DADQDV010000175 DADQDV010000000
VERSION     DADQDV010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1963)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1963)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1963
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.184"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            64..972
                     /locus_tag="J8S10_003094"
     CDS             64..972
                     /locus_tag="J8S10_003094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HAZ9631614.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKINYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FERWRQEQEHSFQDWREGQESDYLAWFESIKDILKTIDPGGVMLAELTDARVDIQGVR
                     HASISERLLADMDYLYQKLRATLFTIEYGEIEVTDILQDDLFSDNHEVEKVGTVAFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            972..1592
                     /locus_tag="J8S10_003095"
     CDS             972..1592
                     /locus_tag="J8S10_003095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631615.1"
                     /translation="MAKTKRMMETDEKTGVQRQFFPITHASAVLGLEEIIAGEATVLS
                     VNGKIGAVVITKEDLGLENVLTELPYASEEDDGIITAEMYQKILNSGEGDYVLPVATI
                     DRLGGIKVGELLTIDETGKVSAVRQSDVNFSLELKEKLDSLKNYTAGENITIDEDGTI
                     SSTGGSGTGGVNQSYVDQKFQEAVNQAENYTNERIPNFTFEKIGEV"
     gene            1596..>1963
                     /locus_tag="J8S10_003096"
     CDS             1596..>1963
                     /locus_tag="J8S10_003096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631616.1"
                     /translation="MTDIVKIKQSNVQVYPQTHWNAIEGKPTMVKGDKGDPGQAATIT
                     IGTVSSGSTASVTNVGTSSAARFNFVLPKGDKGDPGINATTTAVATTTANGLMSSTDK
                     TKLDGIAAGAQKNPGNATTTT"
BASE COUNT          697 a          301 c          443 g          522 t
ORIGIN      
        1 cagtattata gtgcaagtgc aatttcttcc attgtcatac caccaaaata gggaggtgat
       61 ttaatggcaa agtggaatgt catattaagt acaacagaac cctataatta cgtggggatg
      121 attcaagttc gacaaggcaa taagaataca gaggttatgg aagcgactat agttgaaaat
      181 ggtcttccct acgatttatc agaatgtaag gtatattttg aatcagttgt aggtgggaaa
      241 tatccagtcc aattagaaac aaaaattgtg gatgctaaaa aagggaaaat taactatatt
      301 tttgataaat attccatgca gtgtttacat cgacaaacag ccaatttcat tatatttaaa
      361 ggagaagact tgattggaac aactcaagac ttctcttatt ttgtcattaa tgctgtttca
      421 aaaacagaag gagaaatggg ttcttattgg caatcaatcg aagatttaat tgcggatatg
      481 acggacttta ttaatgaaaa taaaggcgat tttacggact ggatgaatga aaggaaagaa
      541 gaatttgaac gttggagaca agaacaggaa cacagtttcc aagattggag agaaggacaa
      601 gaatcagact atttggcatg gtttgaatca atcaaggata ttttaaagac gattgatcca
      661 ggtggagtca tgttagccga actaacggat gcgcgagtag atattcaagg agttcgtcat
      721 gcgtctattt cagagcgttt gctggcagat atggactatt tatatcagaa attgcgagca
      781 acgcttttca cgattgaata cggggagatt gaagtgactg atattttgca ggatgatctc
      841 ttttcagata atcatgaagt cgaaaaagtt ggaactgtag cattcccgat tgaagaagga
      901 gccttgatca tcgcaaccgt tgatgatcca aagcaaaatg tgttcactct tgagaaagtt
      961 ggggtgatct aatggctaaa actaaacgaa tgatggaaac ggatgaaaaa acgggtgtac
     1021 aacgccaatt ctttccaatc acacatgctt ccgcagttct tgggttagaa gaaataatag
     1081 caggagaagc aacagtttta tctgttaatg gaaaaattgg agccgtcgtc attactaaag
     1141 aagatttggg attagagaat gttctcacag aattacccta tgcaagtgaa gaagatgacg
     1201 gcattatcac ggcagaaatg tatcaaaaaa ttttaaacag tggagaaggt gactacgtgt
     1261 tgccagttgc cactatcgac cgtttgggtg gcataaaagt tggtgaatta ttgacgattg
     1321 atgagacagg gaaagtctct gcagtcagac aatctgatgt caatttttcg ctggagttaa
     1381 aagaaaaact cgattcactg aaaaattata ctgctggaga aaacatcact attgatgaag
     1441 atggaacaat tagttctaca ggtggtagtg ggactggtgg tgtcaatcag tcatatgtag
     1501 atcaaaaatt ccaagaagct gtaaatcaag cagaaaatta cacaaacgaa agaattccaa
     1561 attttacttt tgaaaaaatt ggggaggtat agagaatgac agatatcgta aaaataaaac
     1621 aaagcaatgt acaggtttat ccacaaactc attggaatgc tatagaaggc aaaccaacaa
     1681 tggtgaaggg agataaaggc gatcctggcc aagcagcaac aattaccata ggaaccgttt
     1741 ctagtggttc aaccgcttct gttacgaatg taggaacatc atctgcagct agatttaatt
     1801 ttgttttacc aaagggagat aaaggtgatc ctggaataaa tgccacaact acagctgtag
     1861 ctacaactac agcaaatggg ttgatgtcgt ccacagataa aactaagttg gatggaattg
     1921 cagctggagc acagaaaaat ccaggtaatg ctacaactac gac
//
LOCUS       DADQDV010000176         1907 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.185, whole genome shotgun sequence.
ACCESSION   DADQDV010000176 DADQDV010000000
VERSION     DADQDV010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1907)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1907)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1907
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.185"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            582..1817
                     /locus_tag="J8S10_003097"
     CDS             582..1817
                     /locus_tag="J8S10_003097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631617.1"
                     /translation="MSVKKMLFMVSTIIVLTSRFWGINTSLSMRYFIMAIWDLYFMLS
                     YFSYREKTYKKYVIKNNFWLTIMPFVIFSIYTLIIWGIGSNAEFENFIKLCSTLLYLI
                     LAYGYACTAFYLFKAEGIDFIFWSGVISYMSGSVFYLIVSYGLNGLISYIKSLITGET
                     NTANFAMEVHDLTFAMGVFFLYYVFFENKNTKKHKIKIIVSLILIFMGLKRIELLALS
                     GAILVYYVLLKWGKKIQIRALVCTICATVISLVFIYIIDTGILALLMSNLGITDDGAR
                     LSFYLYSSKFYELGLGYVGTGWTWFSKYFFNLYLSHFRLNGGRIAASLHSDILTIYIE
                     VGCIVFIIWMFWLFFVKPIRLTKKFGLKTGECVLLLTIYMFILYLTDNTLTYPDTQMI
                     FLLVPMIVSWVDNQQRISE"
BASE COUNT          663 a          185 c          329 g          730 t
ORIGIN      
        1 acaaaaaaat attataaaga ataatatttt ctaaaaagta aactatagta atgtggatta
       61 tcaccttcca acagtatata aaatgagcgt aaaaacggct atttttgcct taacaacgat
      121 ttttttgtat acaaatacga tatgctcatt aattattgga atttgtagtg ctgtttaaat
      181 taatgaaggt gtaattatat gagtgatcat tttgaaaaag tttgttgaga agatgtgctt
      241 ctagtcatgt gatgggagaa aataatttaa ctgttagagt gaatagttaa attattctgg
      301 ttatatgaaa aaagtagttt ctaaaataat cttgcaggga ttaacttaaa gaaattgaga
      361 gaatagtttc tttgaaattt ctatatacaa tgagaagctg aaatttactt ttatttgatg
      421 actggaaata gaaattaaat atattgtatt gttacattaa agaaaacttg tatggaaaaa
      481 tcagtacaat accattattt aatgttcttc acttaaagcg caaaaaatat cagtttatta
      541 aactcgtata tagaacaaat atatgtagac ggggcgaaac gatgagtgta aaaaaaatgc
      601 tatttatggt aagtacaata attgtattaa catcccgatt ttggggaatt aatactagtt
      661 tatctatgcg atattttatt atggcaatat gggatttata ttttatgtta agctattttt
      721 cttatcgtga gaaaacatat aaaaaatacg ttatcaagaa taacttttgg ttgactataa
      781 tgccgtttgt gatattttct atctatactc taataatatg gggaattggt tcaaatgcag
      841 aatttgaaaa ttttataaag ttatgttcca cgttgcttta tttaattctt gcatatggtt
      901 acgcatgtac agcattttac ttatttaagg cagaaggaat tgattttatt ttttggtcag
      961 gtgttatttc atatatgagt ggttcagttt tttatttaat tgtatcttat ggtttaaatg
     1021 gtttaatttc ttatataaaa agtcttataa caggtgaaac aaatactgca aattttgcta
     1081 tggaggtaca tgatttaact tttgcgatgg gggttttttt cctttattac gtattttttg
     1141 aaaataaaaa tacaaaaaaa cataagataa aaattatcgt atctttaatt ttaattttca
     1201 tgggattgaa gagaattgaa ctgttagctt taagtggtgc aattctagtg tattatgttt
     1261 tattaaagtg gggaaaaaag attcaaatcc gtgcattagt gtgtactatt tgtgcaactg
     1321 ttatttcgtt agtgtttatt tacattatag atacaggaat tttggcattg cttatgtcaa
     1381 atttgggcat tacagatgac ggtgcaaggc tttcatttta tctatattca tctaaatttt
     1441 atgaacttgg tttaggatat gtaggaacag gatggacatg gttttcaaaa tactttttta
     1501 atctttattt atcgcacttt aggttaaatg gtggaagaat tgcagcaagc ctacacagtg
     1561 atatattaac tatttatata gaagttggat gtatagtttt tattatatgg atgttttggt
     1621 tattttttgt gaaaccgata agactaacta aaaaatttgg attgaaaaca ggggagtgtg
     1681 tattattatt aactatatat atgtttatat tatatttgac ggataatacg ctcacttatc
     1741 cagacactca aatgattttt ctcttagtac ctatgatagt ttcgtgggtt gataatcaac
     1801 aacgaatatc ggaatagata gctaaagtat attttaatta tgaatttata attagttgta
     1861 aaagttaata tttaacggac aggaagtagg gtgaaaaaat ttgaaaa
//
LOCUS       DADQDV010000177         1847 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.186, whole genome shotgun sequence.
ACCESSION   DADQDV010000177 DADQDV010000000
VERSION     DADQDV010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1847)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1847)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1847
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.186"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            700..>1847
                     /gene="ltrA"
                     /locus_tag="J8S10_003098"
     CDS             700..>1847
                     /gene="ltrA"
                     /locus_tag="J8S10_003098"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004853597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HAZ9631618.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQK"
BASE COUNT          730 a          281 c          384 g          452 t
ORIGIN      
        1 aaaagctaag gcactaataa aagaacgaaa aagtttggtt attaggagaa ctgataatct
       61 gacaggtgga atgatgaagt aacgctctga aacgcctgcc ctgagcctcc gacaagcatt
      121 gtatgaggaa actcagaatg tttgaagctc ggtaaagacg gctgaaagat accgtaatag
      181 ttgatgaaca tatatcttct atcgaaaact atccagaggt gggtagcgta tccaacaggt
      241 cgggggtcta taaaatatct atggttagaa tgttctataa ggaactgacg aaacagcgaa
      301 tgtacgggtc taaatttgaa ctttgtagaa atgcaaaggt acgagaaatc gtagctggtg
      361 tggcaaagta agaatatagg ttatgaaatg ccatataacg ttacaggcgg tatcaagcca
      421 gcaggcttat agctagtgac ctaaggatat atatgtatag ataagattat cggaacgagg
      481 aaaggtattg ggttctcatc aagagaataa actgacgaag aacaataagc agttgaacta
      541 atgctgaaaa gcagagggcg aacctaagaa attcttgtaa tgagaatgga ggaatgccct
      601 caagtcgtgt atatattaga aaagtattat gttgtttcaa taaggattac gagtaagata
      661 aaaaagctca ctcaatttca agtaaaggag tgaagcctta tgcctaaaaa taaaaatgaa
      721 acattgtgtg tagaagattt aagacacgct gaatattacg aaatgcaaaa cacctttgat
      781 gatttatatg ccaaaagtaa gaatggagat attttcactc atcttatgga tattatccta
      841 tcgagagaaa atatattact ggcatatcga aatatcaaag caaatgcagg cagtaaaaca
      901 gcaggaacag acggtacaat aattaaagat attggcaaat tgccagcaga aacagttgtc
      961 aaaaaagtaa gatacattgt tgcaggcagt ccacatgggt atcgacctaa gccagtgagg
     1021 cgaaaagaaa taccaaaacc aaatggtaaa accagacctc taggtattcc ttgtatgtgg
     1081 gacaggctta tacaacaatg tataaaacaa gtattagaac caatctgcga agctaaattt
     1141 agtgaaaaca gctatggttt tagacctaat aggtcagttg aaaatgcaat aaaagcaacc
     1201 tataaccgcc tacaaatcag ccagctacat tatgtgattg aatttgatat taagggtttc
     1261 tttgacaacg tgaaccattc caagctgata aaacagatat gggctatggg aatacgggac
     1321 aagcacttga tattcatttt aaaaaggata ttaaaagctc caatcaaaat gactaacggt
     1381 acaataacat atccagagaa aggaactccg caagggggaa taatatcccc actactagca
     1441 aacattgttc ttaatgagtt agaccattgg gtagaaagcc aatggcagga aaatcctgtt
     1501 acaaaaaact atgtggttca tatcaataaa agcggtagcc catgtaaaag caacgcttac
     1561 aaagaaatga agaaaacaaa gttaaaggaa atgtatatgg ttcgttatgc agatgatttt
     1621 agagttttct gccgctacaa ggaaagtgct gaaaaagcca aaatagcaat cactcaatgg
     1681 attgaacaac gattaaaatt ggaagtatca caagaaaaaa caagaattgt aaatgttaga
     1741 aaaagatact ccgactttct tggtttcaag attaaaatga taccgagaag aaagaagtta
     1801 gttgttaaat cacatataag tgataaacaa ttcaaaaacc aaaaaga
//
LOCUS       DADQDV010000178         1844 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.187, whole genome shotgun sequence.
ACCESSION   DADQDV010000178 DADQDV010000000
VERSION     DADQDV010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1844)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1844)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1844
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.187"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            469..1641
                     /locus_tag="J8S10_003099"
     CDS             469..1641
                     /locus_tag="J8S10_003099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015077585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="HAZ9631619.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTE
                     YIQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKA
                     LMASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKN
                     YPYLMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEY
                     LKERGLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNIFTTIPKKNSKSFRE
                     AVKGIFKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGFEDAFQYTVQGNSHNRL
                     KSTNLIERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
BASE COUNT          644 a          341 c          301 g          558 t
ORIGIN      
        1 aaaaaagttc aaaagatcaa gtgtgcgctt cgctcccact cccctcgacg ttttagtagc
       61 ctttccctca cttcgttcag tccaagccaa ctaaaaagtt ttcgggatac attctccttc
      121 tcttcctaat aatcaattaa aattttaatc tttatatttc tgctaatcac tcaggaaaca
      181 gtacagaaaa acaaacacgt atcatagata taaatgtaat ggcatagtgc gggttttatt
      241 ttcagcctgt atcatagcta aacaaatcga gttgtgtgtc cgtttttggg cgttctgcta
      301 gcttgtttaa agtctcttga atgaatgtat gttctaagtc aaaaaactct gacagcgcct
      361 ttatatagat aaagtccgta taattgtgta aaagtaaaaa ggccatataa cagtcctttt
      421 acggtacaat gtttttaacg acaaaaacat acccaggagg acttttacat gacccaagta
      481 cattttacac tgaaaagcga agagattcaa agcattattg aatattctgt aaaggatgac
      541 gtttctaaaa atattttaac aacggtattt aatcaactaa tggaaaatca acgaacagaa
      601 tatattcaag caaaagaata tgaacgaaca gaaaaccgac aaagtcaacg aaatggctat
      661 tatgagcgca gctttacgac acgtgtaggc acgctagaat taaaagtacc cagaacacgt
      721 gatggccatt tttcacccac agtgtttgaa cgttatcaac gaaacgaaaa agccctcatg
      781 gcttcaatgt tggaaatgta tgtatcaggc gtttcaactc gtaaagtatc aaaaattgtg
      841 gaagaacttt gtggtaaatc cgtctctaag tccttcgttt ctagcttaac agaacagcta
      901 gaacctatgg ttaacgagtg gcagaatcgt ttattatcag aaaaaaatta tccttactta
      961 atgaccgatg tactctatat aaaagtacga gaagaaaatc gagtactctc aaaaagctgt
     1021 catatagcga ttggaataac caaagatggc gaccgtgaaa ttatcggctt catgattcaa
     1081 agtggcgaaa gcgaagagac ctggacaaca ttttttgaat acctaaaaga acgcggttta
     1141 caaggtacgg aactcgttat ttctgatgcg cacaaaggat tagtctctgc cattagaaaa
     1201 tccttcacca acgtaagttg gcaaagatgc caagttcact tcctaagaaa tatctttacc
     1261 accattccta aaaaaaattc aaaatctttc agagaagctg ttaaaggaat ttttaagttc
     1321 acagatatta acttagcgcg tgaggctaaa aatcgattga ttcatgatta tatcgatcaa
     1381 ccaaaatatt caaaagcttg cgcatcattg gatgatggat tcgaagacgc ctttcaatat
     1441 accgtacaag gaaattccca caatcgacta aagagtacca atctaattga acgactgaat
     1501 caagaagtac gcagaagaga aaagattatt cgcatcttcc ccaatcaaac atcagccaat
     1561 cgcttaattg gagccgttct tatggaccta catgatgaat ggatttattc ttcaagaaaa
     1621 tacatcaatt ttgataagta gaaatggtaa aaacattgta tagcatttta cacaggagtc
     1681 tggacttgac tcacttcctt tattattttt cattttttta aactatttaa tactaatgtc
     1741 ttttataata gcttttcata tattatataa tcaatcttta taagtccttt tataaatttc
     1801 ttttctacca ttttcgataa attcctgttt aatattttta attc
//
LOCUS       DADQDV010000179         1747 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.188, whole genome shotgun sequence.
ACCESSION   DADQDV010000179 DADQDV010000000
VERSION     DADQDV010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1747)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1747
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.188"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            378..1628
                     /locus_tag="J8S10_003100"
     CDS             378..1628
                     /locus_tag="J8S10_003100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAZ9631620.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     ETILEFNNSYHFDQIVIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFS
                     RMFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQH
                     FLENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGK
                     GRFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQ
                     VIVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQ
                     SQNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARK
                     FTRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT          578 a          334 c          308 g          527 t
ORIGIN      
        1 taatagtttt tattcaaaat gtttctagat tataaaattt attgaataac acattcctaa
       61 cggaatttgt ttcgatattg tgtgatttct cagagtacaa tggatgtatg gaaaggatcc
      121 aacgggaatt tgctatttcc tcctgtagcg tttgtctacc ctgtttagtc tgttacccga
      181 accactgtta tcactaccaa ctcattagct gtttcgataa tggactagac tttcaaatag
      241 tagtttggaa ggcagcttct agctctttta tcaccgtatt ctattaggcg aggttgtggc
      301 tatacagtga gtttctggga aatcccacag tatcgaagca ttttccaaaa tttatatcga
      361 aaggaggtcc ttcttccatg aaattatttg tcggtattga cgttagctct gaaaaactag
      421 atgtttgttt tttaacagac gacaatcaat tgtctatctt atctgaaatc tctgttgcca
      481 atgacatcga aggtgcttca ttcatacgag aaacaattct tgaattcaat aacagctacc
      541 actttgatca aattgtgatt ggcatggagt caacgtccat gtacagcttc catccttcca
      601 tgttttttca tgaagatgag aaactaaaga agctcaacac acttgtaacg attgaaaatc
      661 cttttcgggt gaaacaattt agtcgcatgt ttgatgagaa taaaactgat cgaaacgatg
      721 cattaagaat cgctgatttc ttgcgtattc aacgattcac aacttcccct atcaaagaag
      781 agaaatacat ggccttacag cgtttaacac gtactcgcta tcaacttatt aagcaattga
      841 ttcgtacaaa gcaacatttt cttgaaaatc taacgtacaa atgtaatacg cttgctcgag
      901 aaatgcgaga cgaatcgacg agtcttttta gtgcaaccct catttcactc atgacggaag
      961 atttcacatt ggatgaactt gctgagcttc ctttagaagc tttctgtgat ttacttcaag
     1021 aaaaaggaaa aggccgtttc aagcaaccag aaaaaatcgc taaagcaatt caacgtgcaa
     1081 ttaccatgag ttaccgccta ggtgctcttg cacaagaatc aattaatgtt gttttaagtg
     1141 ttctcgtacg agaaatacga gcacttgaaa aaaatatcaa agaattagat aaagccatcg
     1201 aacaagtaat tgttgtcatt ccagaatatc aatgcttaac cagtattcca ggcgttggta
     1261 aagtctatgc tgccggttta atcgctgaaa ttggtcaaat cgaaagattt gaagatcaga
     1321 caaaattggc aaaatacgct ggattaagtt ggaaagtgaa ccaatctgga aactatcagt
     1381 cgcaaaatac acctctgaca aaacaaggaa atcgatattt tagatactac ttagttgaag
     1441 ctgccaactc tgtaaaaaat tatcttcctg aatacaaagc tttttatcaa agtaaatata
     1501 aggaggttcc aaagcatcaa cacaaacgtg cactcgtcct aaccgcaaga aaatttacgc
     1561 gtctggtgga tacgctacta cgtaaacacc aactctatac gccaccaagg agtgtgatag
     1621 agaaataaca atccgttatt gacgcaaatc cttgaatcaa cccgaaaaaa atttgatttt
     1681 gatcgggtct agtttcgtgc gcttcaaaac atattactca ataaagaaaa tcttaaattt
     1741 catcttg
//
LOCUS       DADQDV010000180         1732 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.189, whole genome shotgun sequence.
ACCESSION   DADQDV010000180 DADQDV010000000
VERSION     DADQDV010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1732
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.189"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..1026
                     /locus_tag="J8S10_003101"
     CDS             <1..1026
                     /locus_tag="J8S10_003101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631621.1"
                     /translation="PTATPYQPNLLDAPYYLSKVALGENIADPTVSFPIKTSAYRLYG
                     VNMLEEFKVGQRYTITIKGTKPATQDFWVFNSGDVSLGKMKPVEGLSDIWTLTFTPNA
                     VNSSTPKLLAIYQTPQSTAGACQIDWLKIEKGDTRTPNIGEYKYRGTGMRDSNNPKDY
                     VWDLAPEYVEDNLATDIKISEITGKANNYTDGKVSEINSQLTASINEVDTTAKDAQTK
                     ANANATAIDELDNKIDERINDTATTTLTVTNGNTGSAKLYREGKTVSIYFVALNGKSS
                     GGNDSTILTIPEGYRPPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYGSDYT
                     FAITYTI"
     gene            1189..1635
                     /locus_tag="J8S10_003102"
     CDS             1189..1635
                     /locus_tag="J8S10_003102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631622.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGIRADGEPL
                     TIADQMFDPKLNQWIILANALDHNDLNNLKAMYESLENENGDLKQINAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPASKGGE"
     gene            1637..>1732
                     /locus_tag="J8S10_003103"
     CDS             1637..>1732
                     /locus_tag="J8S10_003103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HAZ9631623.1"
                     /translation="MFSFSDVKMMYDWGCFTNEQVMVFVPLCITEE"
BASE COUNT          623 a          301 c          360 g          448 t
ORIGIN      
        1 ccaacagcca caccatacca gccaaattta ctcgatgcac cgtattattt gagtaaggtg
       61 gctttgggcg agaatattgc tgatccaaca gttagcttcc caattaaaac gagtgcatac
      121 cgtttatacg gtgtgaacat gctagaagag tttaaagttg gtcaaagata tacaattaca
      181 ataaaaggaa ctaaaccagc aactcaagat ttttgggtgt tcaattctgg agatgtttca
      241 ttaggaaaaa tgaaaccagt agaaggctta agtgatatat ggacgttaac ttttacacct
      301 aatgcagtta atagtagcac acctaaacta ttagctatat atcaaacacc acaatcaaca
      361 gcaggcgcat gccaaattga ctggcttaag attgaaaaag gcgacacccg aaccccgaat
      421 attggtgagt ataaatatcg tggtactggt atgcgtgatt caaacaatcc aaaagattat
      481 gtttgggatc tagcaccaga atatgtcgaa gataatttgg ccacagatat taaaatttct
      541 gaaattactg gtaaagcaaa caattatacc gatgggaaag tatcggagat taattcgcag
      601 ttgactgctt caattaatga agtagacacc acagctaagg atgctcaaac aaaagcgaat
      661 gctaatgcga ctgctataga tgaattagac aataagatcg atgaacgcat taatgataca
      721 gctactacca cattaacagt tacaaacggg aataccggat cagcaaagct ttatcgtgaa
      781 ggaaaaacag tttctatata ttttgtggct ttaaacggaa aaagcagtgg tggaaatgat
      841 tcaacgatac taacaattcc agaaggctat cggccaccaa ttagttttga gcaactggtt
      901 ggctcgatag accgttctac tttgaacagt gctcagttat ctattggtgc agatggagcc
      961 attaaatggc gaagaaactc aagttatgga tcggattata cctttgcaat tacttacacg
     1021 atttagaaaa gcgtgaatcg atatgaaggc agcatataga ccaattgaac cttacggatt
     1081 cgagcaaatc attgtgaatg atgaagaaca tttaccggaa gaatgcacag aagtcgaacc
     1141 accgattcca aattggaaac cgaaattcaa ttactgggag ggaaataaat gaaaaacatt
     1201 tggaaatatg gacgtactgg cggagagtac gcaggaaaag tattggacga catgcttgta
     1261 tccgttcctt acacagatca gccaccgctt gaaggaattc gtgctgatgg cgaaccgtta
     1321 acaatcgctg atcaaatgtt tgatcctaaa ttgaatcaat ggattatttt agcgaacgca
     1381 ctagatcaca acgatttaaa caatctcaaa gcaatgtatg agtcgttaga aaatgagaac
     1441 ggcgatttaa aacagatcaa tgccaaactc atgctaagcg atgtagcaat taaacaggaa
     1501 aatactgcat tgaaagaaaa agcggatagt ttagcacaaa tcaattcaaa aatgatgctt
     1561 gcttcgttac aaaatagcaa agacatttca gaaattaaag agcaactaaa tccagcttca
     1621 aagggaggtg agtagtatgt ttagttttag cgatgtgaaa atgatgtatg attggggctg
     1681 tttcactaac gaacaagtaa tggttttcgt tccgttgtgc attactgaag aa
//
LOCUS       DADQDV010000181         1686 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.190, whole genome shotgun sequence.
ACCESSION   DADQDV010000181 DADQDV010000000
VERSION     DADQDV010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1686)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1686)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1686
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.190"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(114..1262)
                     /gene="tnpB"
                     /locus_tag="J8S10_003104"
     CDS             complement(114..1262)
                     /gene="tnpB"
                     /locus_tag="J8S10_003104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family element transposase accessory
                     protein TnpB"
                     /protein_id="HAZ9631624.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYTTNNQNGTVALIDSKFIKVPKLKSLVRIKLHRQPKGIIKSATISRHSS
                     GKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFTSKMEKKLKREQ
                     RKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNKLSTEMIKNHDI
                     ICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKVDKWFPSSQICS
                     ECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLHSMGLA"
     gene            complement(1279..1683)
                     /locus_tag="J8S10_003105"
     CDS             complement(1279..1683)
                     /locus_tag="J8S10_003105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HAZ9631625.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLWKE
                     MFWSKSFCLLTTGGAPIDVIKKYIQNQGNNHK"
BASE COUNT          498 a          290 c          267 g          631 t
ORIGIN      
        1 agtgggagct tcttgggaat agagcatact tgatagcgta tttctttact aacagcggtg
       61 tctcttattt accaagctat ccccgtagtt cctacggttc ttgatgattg gatctaagcc
      121 aatcccatag aatgtagtct tagaccttcg gtcagaatat tgatactagc attgatatca
      181 cgatcatgat gagtatgaca aacaggacaa gtccattctc gaatttcaag agatttcttg
      241 ccatctttat gtccgcactc tgaacaaatc tgactagacg gaaaccattt atctactttg
      301 atgatttttc gtccatacca gtcagccttg tattgtaatt tagtcacaaa ctttgaccaa
      361 gaaacatcag aaatactttt agctaattta tgatttcgca acataccttt tgtgtttaag
      421 tcttcaatac agataatatc gtgatttttg atcatttctg tactcaactt attcagaaaa
      481 tcagtacgtt gattcattac tttttcatgc aatctagcta ctttgcgttt ttgtttttga
      541 taatttttag cttcaaatag attggtacct ttatttttag ccaataaagc acgcctagac
      601 aatttgcgtt gttcacgctt tagtttcttt tccattttgg acgtgaattt attattatca
      661 attttttgtc catcagaaag aatcgcaaag tccataatac ctaagtcaat accaattgtg
      721 gaattagttt taggtaattc gataatttct tctttacaca acaaagaaat atagtattta
      781 ccgctagaat gacgtgatat tgtagcagat ttgataatcc cttttggttg tctatgaagc
      841 ttaattctta ctaatgactt caatttagga actttgatga atttactatc aatcaaagca
      901 actgtaccat tttgattatt cgttgtataa ctctgaacag gatttttctt acttttgaaa
      961 cgtggaaatc caacggattt atcccgaaaa aaattcttgt atgctttatc taaattaagt
     1021 tgggcattgg ctaaagcaag gctatcaatt tctttcaaaa acggaaattc tttcttgtat
     1081 ttagctggtg tcggaaaagt cattttttta gaagaatcat ttttaacttc ttcatacgcc
     1141 ttttttcggt catcaagcat tagattgtag accttacgga cacaaccaaa agatttggca
     1201 aagaagattt cttgttcctc tgttggatag attctgaatt tgtatgcttt tagttgttcc
     1261 ataaagttca cctactttct atttatgatt gtttccttga ttttggatat acttcttaat
     1321 cacatcaatt ggtgcgccac cagttgtcag aagacaaaaa cttttagacc agaacatttc
     1381 tttccaaaga aattgtttga ctcttggaaa gtcacgtttt atcaatcttg agctggcact
     1441 tttataggca ttgatgaatt ttgtcaattc tgttttaggt tgagctttga acataatatg
     1501 aacgtggtct ttatcatgat tccactccac taaagtaatg tgatacgatt ctgaaattct
     1561 ttcaaaagta gttttggcat aatcagatat ttcatcatca atcacttgtc tacgatattt
     1621 cgttactaaa acaaggtggt aataaagaag aaatactgaa tgattatttg tatctaattc
     1681 catgtt
//
LOCUS       DADQDV010000182         1654 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.191, whole genome shotgun sequence.
ACCESSION   DADQDV010000182 DADQDV010000000
VERSION     DADQDV010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1654)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1654)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1654
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.191"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..1144
                     /locus_tag="J8S10_003106"
     CDS             <1..1144
                     /locus_tag="J8S10_003106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAZ9631626.1"
                     /translation="NHEVKTIDADKKTVTVTSASDNETKEYPYDKLILSSGVKPNNLP
                     VPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVGAGYIGIEAAEASRKAGKEVVL
                     LDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKIEAFTGNGKVEAIKTSEKEIPA
                     DLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTNLPDVYAVGDATLAYSIPARKK
                     MPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSALSVFDYHFAASGLNSFTAAKA
                     GVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMTHQLLGGAVLSTYDVTGQGNVL
                     ALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQALGEEPFVE"
     gene            1425..1654
                     /locus_tag="J8S10_003107"
                     /pseudo
     CDS             1425..1654
                     /locus_tag="J8S10_003107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          591 a          293 c          356 g          414 t
ORIGIN      
        1 taatcacgaa gtaaaaacga tcgatgccga taaaaaaaca gtaacggtta ctagcgcatc
       61 agataacgaa acaaaagaat atccttatga caaattgatt ttgagttctg gtgtcaaacc
      121 aaacaatctg ccagtaccag gagcagatct agaaaatgtc tacttgatgc gtggatacaa
      181 ttgggcaacc aaaatcaaag aaaaattaaa tgatccggct attaaaaaaa tcgctgtcgt
      241 aggtgcgggt tacattggga tcgaagcagc agaagcaagc cgaaaagctg ggaaagaagt
      301 cgtattgctt gatgtgatcg atagaccttt aggcacttat ttagatgctg agatgacaga
      361 tattttagaa caacacctaa atgaaaacgg tattgaagtt ttgacaaatg caaaaatcga
      421 agcttttact ggtaacggaa aagttgaggc aatcaaaaca agtgaaaaag aaatcccagc
      481 agatctagtc attcaagctg ccggtgtgaa ggcaaataca gaatggttaa aagggatcgt
      541 cgacttagat gaacgtggct ggatccaaac aaatgaatac ttgcaaacga atcttccaga
      601 tgtgtatgca gtaggagatg ctacacttgc ttattctatc ccagcacgca aaaaaatgcc
      661 gatcgcttta gcgactgttg cacgtagaga agcacgttat gtagtaaaac atctttttga
      721 agaagtacca aacaaaccgt tcggcggagt cgtaggttcc tctgcattaa gtgtctttga
      781 ctatcatttt gcagcaagcg gattgaatag ctttacagca gcaaaagcag gagtagatgt
      841 acgagtgtct tattatgaag atacgttacg accaaaatat gtaccagaag aacaaggaaa
      901 tccaaaagtg tccatccaat tattctcgga tccaatgacc catcaattgc taggaggagc
      961 agtattatct acctatgatg ttacaggtca aggaaatgta ttggcactag cgatccaaaa
     1021 caaactgact ttagaagaac tagcagaagc tgacttcttc ttccagccag gctttgaccg
     1081 acaatggagc atgttgaatc tagccgctca acaagcgtta ggagaagaac catttgtaga
     1141 ataagaaaac gaaatatttg aaaagaggtt gtgaaaaagc tgccttgcat caagtaataa
     1201 gaacagccaa gtaaaaacag cttcttatgt ttttaacttg gctggactta ttaccgcaga
     1261 tgcaagcttt tgaacaccgt ttattttcaa aaaagggact gtgacacgat ttgtgtaccg
     1321 acccccaaaa gttagaccaa aaaatctaac ttttggaggt cggtattttt tatggttaaa
     1381 tatacttttg aacttaaatt aaagatcgtt catgattatt tggatggcaa aggcgattgg
     1441 accgtaaaaa tccagatcaa gagattgaag cggaaatgct taaaattcgg gagaagcaca
     1501 aggattatgg ctgtttacgg atgaccaatg aactaagaaa ccgcggtttc tctatcaata
     1561 aaaagaaagt tcagcgcttg atcaagaagc taggaataaa agtaacggca tacacgcgta
     1621 aatcacgtcg ctacaattct tatcgaggaa aagt
//
LOCUS       DADQDV010000183         1622 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.192, whole genome shotgun sequence.
ACCESSION   DADQDV010000183 DADQDV010000000
VERSION     DADQDV010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1622)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1622)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1622
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.192"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            1..117
                     /locus_tag="J8S10_003108"
                     /pseudo
     CDS             1..117
                     /locus_tag="J8S10_003108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
BASE COUNT          614 a          189 c          327 g          492 t
ORIGIN      
        1 cgcatctaaa cgaaataata ttcctagaaa atcactggat tatcgaacga ttatcgaaca
       61 cctttggaag tatttttgag ttacgtaagt attgatgatc tgtctaattt aatttgacaa
      121 ttaagaaagt attaacttgt tttgtgaaaa agagaatttg aaaaacgatt ggcgaacaaa
      181 tgctcggtag gtatggtata aatacagagc taattggtgt gatgaaatca gatattcgcg
      241 tgagattcag taaagtagga gttcgaaaac agctaggtga caaacagtat tgctttggta
      301 cttcggaatg gtttatcaaa ttcttatcaa cagttcactt ctctttatgt ttgagtgatg
      361 attcgttagg ttattgcttg gaaagaccgg atgagagtag aagagtttaa ttttataaag
      421 tgaaaagagg taatgtacga tatacgtagg gctgaaccaa tagaggataa gcaaacgatg
      481 ttacaggcgc aaaattcata gcttactgtt ttggagataa cagaagagga aataatgcag
      541 aagtaaggcg aaaaaaggac ggaagcctaa cagcatatga aataaagaaa aatattataa
      601 ctactgataa atcggtattg agcaaagtac taataggagt caaaaacatt cataagctat
      661 gagtgtttct tggctacttt tttattttta tgtatctaca aaagtttcca ggggcagaac
      721 ctgtgattat taatggaaga acctcaagta ttgtcttaaa tcattgttat gaaaatggat
      781 taaaagagtt catcaaggtg tgattaacaa gttacttttc attacatcga atttttcaga
      841 agttgcttat attggtgatg atattaatga tttatcatgt atgacatctg tgaagaagcg
      901 ggaggaatag tagaatgtcc aaaaaatgcc acaagaaatg agattgaatt atctgatttt
      961 attgtaactc acagtggtgg tgacgaatct gtgatagagt ttattgagtg gatattggaa
     1021 tcgatatagt gtagtagtac agaaaaatta tcatacaatt aatactaggc ataagaatat
     1081 tggcatattc tagagttaaa agtaactatt cgaaaaggat aaggttagaa ttttttgttt
     1141 tgccagtgga agaatataaa aagggcattg gaaattaata tattagaatg ctaagcggag
     1201 aaaaaaatat atgaaaagta cgtccttgtg atgggatgga aaaatacact tatttcaaac
     1261 aacgataata taattatgtg aaccgaagta tactcgcttc taattcaatc ctcaaatccc
     1321 gacagtcgcg acttcaaaaa agcgtatagt tttaatgtat ccccatatga tccgaaaaat
     1381 ggtaatttac aattaacagt ttgatgatgt tgaagatgtg gaaatgctga aattaccatg
     1441 atgagaaaca cattaattaa agggaattaa ttaactagaa tataatctga ttcaatttga
     1501 attaagcaaa aaaaggctga gttttaaata atcgcgaatt gtaaaattaa gttagaaaaa
     1561 taaaaaggca tttatggtac actcaaattg tatttccgac gaaagaaaac aaaggagtgt
     1621 aa
//
LOCUS       DADQDV010000184         1570 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.193, whole genome shotgun sequence.
ACCESSION   DADQDV010000184 DADQDV010000000
VERSION     DADQDV010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1570
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.193"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            60..1526
                     /locus_tag="J8S10_003109"
     CDS             60..1526
                     /locus_tag="J8S10_003109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HAZ9631627.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
BASE COUNT          436 a          291 c          330 g          513 t
ORIGIN      
        1 aatttttcgg taaagatgta taatattttc tgaaaattta aagaattggg gtatagatta
       61 tggaaaaaca gcaagacaag ggcttcttcg ggcagccgaa gggattgtca actttgttct
      121 tcactgagat gtgggaacga tttagttatt acggtatgcg tgcattactt atctattata
      181 tgtacgatac agttgccaac gggggacttg gattaccacg agcaacagca ttagctatca
      241 tgtcgatcta cggatctttg atctacatgt ctagtatcgt cggcggatgg gtatctgacc
      301 gagtgttagg agcaaaacgc actgtattct tcggtggagt tttcattatg cttggccaca
      361 tcgtcttggc tttaccattt ggtgtaagta cattgtttgt ttcgatggca ttgattatta
      421 tcggaaccgc ctttttgaaa ccaaatgttt ctggcatggt cggacatctt tattcaaaga
      481 ctgacttgcg aagagatgca ggattttcga ttttttacat gggtgtcaac ttaggggcat
      541 tattagcacc actaatcgtt ggtacaatcg gtcaagaata taactatcat ttagggttct
      601 ctttagctgc tattgggatg ttctttggat tattacaata catcatccaa ggacgcaaga
      661 cattagacgg agtgggtaca acaccgccga atcctttgac aactgaagaa cgtaaaggat
      721 tcatccgtaa cttgatcatc gcacttgttg ttatcgctgc agtattcggc ggggcacaac
      781 taactggtca tctgacaatt gacttttttg tcaatacaat cagtgtattg gggattatct
      841 taccgttgta ttactttatc aaaatgctga cttcaaaaga tgtaactgct gaagaaaaac
      901 caagagtatg ggcttatatc ccattattcc ttgcagcaat cattttctgg tcattacaag
      961 aacaaggttc atctatctta gctttatttg ctagtgaacg tacacaatct acgctatttg
     1021 gtgtaacgat ccaagcaagc tggtatcaat cattgaatcc aattttcatc tttattctga
     1081 caccagtatt cgtaacgatg tggacgaaac ttggtgaacg tcaaccatct acagtagtga
     1141 aattctctct tggactttta tttgcaggat tatcgtactt gctattgatg ttgccgggta
     1201 tgctttatgg tacaagtgga aaagtaagtc cattgtggtt gttgggaagt ttcttcatcg
     1261 tggttattgc tgaattgtgt ctttcaccag ttggtttgtc tgtgacaaca aaattagcac
     1321 cacgagcatt tgaatcacaa acaatcgcta tttggttctt agctgatgct tcttcacaag
     1381 caatcaatgc acaaattgca cgcttctaca caccgggaac agaatctgct tacttcggta
     1441 ttatcggtgc agtagcaatc gtcggtggta tcttgctatt tactgtgaaa gaaccaatca
     1501 aaaaactaat gggctctatt cattaatcaa tgaacataaa aacaggaatt gcttatttgc
     1561 agcagttcct
//
LOCUS       DADQDV010000185         1480 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.194, whole genome shotgun sequence.
ACCESSION   DADQDV010000185 DADQDV010000000
VERSION     DADQDV010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1480
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.194"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            64..972
                     /locus_tag="J8S10_003110"
     CDS             64..972
                     /locus_tag="J8S10_003110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HAZ9631628.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKIKYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FDRWREEQENSFQDWREGQESDYLSWFESIKDILKSIDPGGVMLAELMDARVDLQGVR
                     HESISERFLSDLNYLYQKMKAALFTIEYGEIEVTDILQDDLFSDNHEVEKIETVEFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            972..>1480
                     /locus_tag="J8S10_003111"
     CDS             972..>1480
                     /locus_tag="J8S10_003111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631629.1"
                     /translation="MVKVKRMMETDESGVKRQFMPITHVSAVLGLEKMISGQSKVLSV
                     NGKYGAVILTKADLGLENAITELPYASETSDGILTAEMFQKIVNGEGGTYILPIATPE
                     QLGGIKVGELLEVTEEGVLSATKQTDFNFSEELKGKLESLKILKAGANISIAEDGTIS
                     STGGSGTGGV"
BASE COUNT          529 a          197 c          316 g          438 t
ORIGIN      
        1 cagtattata gtgcaagtgc aatttcttcc attgtcatac caccaaaata gggaggtgat
       61 ttaatggcaa agtggaatgt catattaagt acaacagaac cctataatta cgtggggatg
      121 attcaagttc gacaaggcaa taaaaacact gaagttatgg aagctacaat tgtcgaaaat
      181 ggtcttccat atgatttatc agaatgtaag gtatattttg aatcagttgt tggcggaaaa
      241 tatccagtcc aattagaaac aaaaattgtg gatgctaaaa aagggaaaat caaatatatt
      301 tttgataaat attccatgca gtgtttgcat cgacaaacag ccaatttcat tatatttaaa
      361 ggagaagact tgattggaac aactcaagac ttctcttatt ttgtcatcaa tgctgtttca
      421 aaaacagaag gagaaatggg ttcttattgg caatcaattg aagatttaat tgctgatatg
      481 acagatttta ttaatgaaaa taaaggcgat tttacggact ggatgaatga aaggaaagaa
      541 gaatttgatc gctggagaga ggaacaggag aatagtttcc aagattggag agaaggacaa
      601 gaatcagatt acttgtcatg gtttgaatca atcaaggata ttttgaagtc tatcgatcca
      661 ggtggagtaa tgttagccga attaatggat gcacgtgtag atcttcaagg tgtacgccat
      721 gaatcgattt ctgaacgttt cctatccgat ctaaattatt tgtatcaaaa aatgaaagca
      781 gcacttttca cgattgaata cggtgaaatt gaagtgactg atattcttca agacgatctc
      841 ttttcagata atcacgaagt cgaaaaaatt gaaacagtag aatttccaat tgaagaagga
      901 gctttgatta ttgcaactgt tgatgatcca aaacagaatg ttttcactct tgagaaagtt
      961 ggggtgattt gatggttaaa gtaaagagaa tgatggaaac tgatgaatct ggtgttaaac
     1021 gtcaatttat gccaattaca catgtctctg cagttttagg cttagaaaaa atgatatcag
     1081 gacaatcaaa agttctttcg gttaatggta aatatggtgc agtcatttta acgaaagctg
     1141 atttaggatt agagaatgca attactgaac taccttatgc aagcgagaca agcgatggta
     1201 ttcttactgc tgaaatgttt caaaagatcg taaatggaga aggtggaaca tatattttgc
     1261 cgattgctac tcctgaacaa ttaggaggta taaaagttgg ggaactctta gaagttactg
     1321 aagaaggtgt tttatctgca actaagcaaa cagacttcaa tttctctgaa gaattaaaag
     1381 gaaaattaga atctctaaaa atattaaaag caggtgcaaa tatatcaatt gcagaagatg
     1441 gaacaattag ttctacaggt ggtagtggga ctggtggtgt
//
LOCUS       DADQDV010000186         1424 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.195, whole genome shotgun sequence.
ACCESSION   DADQDV010000186 DADQDV010000000
VERSION     DADQDV010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.195"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(150..1337)
                     /locus_tag="J8S10_003112"
     CDS             complement(150..1337)
                     /locus_tag="J8S10_003112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HAZ9631630.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT          414 a          309 c          249 g          452 t
ORIGIN      
        1 taaaagttca acctcatcaa aagcacaatg ttttgcgttg tgaacctaac tgccatgcct
       61 ttctttctga ggagagaggt caggagcagt agcgcagcga ctcttgatgt ctctcctcag
      121 aaagaagaga ctcgcacagg ttcatggtgc taaatgttat tcgaattaaa ttctaaatat
      181 tttcgtggag aagccagcca ctcagtgtct ttttccatca aaagtgttcc aattatccga
      241 gtgatggaat tgatatttgg aaaaatccga atcactcgtt ctctccggcg aatctcttcg
      301 ttcaaccgtt ccaacacatt ggttgtacga atccttcggc ggatattttc aggaaaagac
      361 aaaatttgaa tagcatcttc aaagccgttt tctaaaatgt cgcaagcagc acttaatttt
      421 gaatcacaac catatttttc caagaagtgc tcttttcttt cacgtgtcaa ttcaagttca
      481 gaggctttaa agatactctt caactcgtct tttacatcag aagaaacttt ctttggcagc
      541 ttatcaaaaa tatttctcaa aaagtgggct tggcatcttt gccagctcgc acctaaaaag
      601 ttcttgcgaa cagccttaac taaccctttg tgtgcatcag aaatgaccag ttttacaccg
      661 aacaaacctc gttgaacgaa cgattgaaaa acggtatccc aattatcttc cgattcgccg
      721 tcttgaacat caaaaccaag aatcgtacgt cgtccatcag aatcaatgcc gataccaata
      781 tatacacctt ttgagacaat acgatgattt tcccttactt tcatatacag ggcatcacac
      841 atgaaaaatg gatattccga gccttctagg ctccggtttc tccactcaaa aacaaatgga
      901 tccaactgtt tcatcagatt tgaaacgaat gatttagaaa cagtcgcacc atccgttagc
      961 agttcaactg ttttagttac tttgcgagtg gagacaccag aaatgaccat ttcaatcatg
     1021 gcagcgatca aagctttttc gcttcgctga tatctttcaa agatagtagg actaaactta
     1081 ccgtctctgg ttcgtggaac atgaagttct aacgtaccaa ttcgagttgt aaacgaacga
     1141 tcgtagtaac catttctttg tgattgccgt tcttctgaac gttcataggc atttgcctga
     1201 atatattgat ttcgttgttc ttccatcagc tgattaaaca tgatagtcat aagtgttttt
     1261 gcggtatcat tcgcaccgct ttcgtttata attgcttgaa tttcttcgct ttcaaaagta
     1321 aaatgtactt gagtcattga tatcagtcct attcgagtat gttttctgca aaaaacattg
     1381 tactcctaac tgagatcaat ggcttttttg atgcttcact ttta
//
LOCUS       DADQDV010000187         1416 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.197, whole genome shotgun sequence.
ACCESSION   DADQDV010000187 DADQDV010000000
VERSION     DADQDV010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1416
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.197"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..689
                     /locus_tag="J8S10_003113"
     CDS             <1..689
                     /locus_tag="J8S10_003113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HAZ9631631.1"
                     /translation="KNKEAVTTSLQVAESFDKKHRHVLTAIDELKEGVAENWADLFWE
                     DTYVHPQNKQSYRIIYMNRDGFSLLAMGFTGKKALSFKLQYIEAFNKMEKELKDQLPS
                     IPATKREMALLALAANEETNERVDAIESDLNDLKNNQLLAEPDYRTISNMVRNKIRVI
                     CNQQHLNSKAKAELFKDLNGGIKRITGAVARNRIKAKQFDDVIDFINNWMPSTATMTI
                     IKQMELLEDE"
     gene            868..1209
                     /locus_tag="J8S10_003114"
     CDS             868..1209
                     /locus_tag="J8S10_003114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631632.1"
                     /translation="MKKELSTLDQYLTDPSWGKSNIKETSNRKIRRNLLTDEELACDQ
                     DDLGNFVSIWDHVYLIHLSRKSKKTEYIYVIEDGLIDALEEYDRDNLIDISYYGSGKK
                     YIAEMEAEFDE"
     gene            1202..>1416
                     /locus_tag="J8S10_003115"
     CDS             1202..>1416
                     /locus_tag="J8S10_003115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HAZ9631633.1"
                     /translation="MSEKEQPLKNRSDNTLFNTLYKINVKDVTEKRNNLTYLSWAWAW
                     AEVSKVCEAVDYEIYHDPETYLPYVFD"
BASE COUNT          538 a          222 c          287 g          369 t
ORIGIN      
        1 tgaaaaataa agaagctgtg actacgagct tacaagttgc agaaagcttc gataaaaagc
       61 acagacatgt tttgacggct attgatgaac taaaagaggg ggttgccgaa aattgggcag
      121 acctattttg ggaagatact tatgttcatc ctcaaaataa acaatcatac cgaattattt
      181 atatgaatag agacggcttc tctctattag caatgggctt cactggtaag aaagctttaa
      241 gttttaaact tcaatatatt gaggccttca acaagatgga aaaagaatta aaagaccaat
      301 tgccatcaat tccagcaact aaacgagaaa tggcattact tgctctagct gcaaacgaag
      361 aaacgaatga aagagtagac gctatcgagt ctgatttaaa cgatttgaag aacaatcaac
      421 ttctagctga accagattac cgaacaattt ctaatatggt tcgcaacaaa attagagtta
      481 tttgtaatca gcagcattta aatagcaaag caaaagcaga attgtttaaa gacttgaatg
      541 gcggaattaa gcgaatcact ggagcagtag ctagaaatcg tatcaaggca aaacagttcg
      601 atgatgttat cgattttatt aacaattgga tgccttctac agcgacgatg acaattatta
      661 agcaaatgga gttgttagag gatgaataga gctgaagcgc taaaaatagg cgtaataatt
      721 gctaatcgct ggtggagaca caataaacca aacatcctaa gccaacaaca tattgataag
      781 caaaaagcat ggcaacaaat aaaaaagtga ctcagccgac caaagcaatg agtcacaaag
      841 aaaatacatc taaggagatg ttaccacatg aaaaaagaac tttccactct agatcaatat
      901 ttgactgatc ctagttgggg caaatcgaat atcaaggaaa caagcaatcg aaaaatcaga
      961 cgtaatcttt tgacggatga agaactagca tgtgatcaag acgatttggg aaattttgtg
     1021 agtatttggg atcatgtcta tcttatccat ttatcgagga agtccaaaaa aactgaatat
     1081 atctatgtca tcgaagatgg cttgattgat gcgctagaag agtatgacag agataacttg
     1141 attgatatct cttattacgg atcaggtaag aaatacattg ctgaaatgga ggcagaattt
     1201 gatgagtgaa aaggaacaac ctttgaaaaa tagaagtgat aatacgcttt ttaatacctt
     1261 atacaaaata aatgtgaaag atgttactga aaaacgaaat aacctcactt atctttcgtg
     1321 ggcatgggct tgggcagaag ttagcaaagt gtgtgaggca gtagattatg aaatctatca
     1381 tgatccagaa acatatctgc cgtatgtctt tgataa
//
LOCUS       DADQDV010000188         1391 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.198, whole genome shotgun sequence.
ACCESSION   DADQDV010000188 DADQDV010000000
VERSION     DADQDV010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1391)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1391)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1391
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.198"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            94..1389
                     /locus_tag="J8S10_003116"
     CDS             94..1389
                     /locus_tag="J8S10_003116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAZ9631634.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVLKRNAYGFRNFYNFKLRIMIRHGKTFLTK"
BASE COUNT          442 a          276 c          260 g          413 t
ORIGIN      
        1 tcaccaacat cttttttgta taaaaaaata tagaaaagac accctgaaat cctttagaat
       61 taatttggct accaattcat aggaggattc aagatgtctc atactcagct tatcaaagat
      121 accctaaata ttctagacct aaatatctat ttcgaggaaa attgtttaac taaagaaaaa
      181 tacaaagggc aaatttgctt gatttacaaa ggaactcttc tgtacaagcc agaagagtgt
      241 tcccattgtc tttgtgtcgt cccctctagg atcattcgtt gggggacgac aaccgttcgg
      301 ttgttactga atgatgtgtc tgagtatcgc acttatctgg agctgaagaa acaacgattt
      361 aaatgtaagt cttgccaaag aacattcgta gcggatacct ctgttgctga aaaacactgt
      421 ttcattagtc aaaaagttcg ttggtctgtc attgctcgct taaaagagaa tacttccatg
      481 acggaaatcg ctcgtcagaa aaatatttcc acttcttcgg tctatcgtgt catgaagcga
      541 ttctaccgcc cattgaatcc tttcaaacag actttgccaa aggtcttatg ctttgatgaa
      601 ttcaaatcgg ttcgaagtgt tgccagtgca atgagtttta tcatgatgga cggacaaagc
      661 catgcattat tggatattgt cgaaaatcga cgcttgcctt atttagaacg ctatttttct
      721 cggttttcat tagcgactcg tgaagccgtt caattgattg ttattgatat gtatgcgcct
      781 tatgtttcgt tggtgaaaaa gcttttcccg aatgctcagt tgatcatcga tcgtttccac
      841 atcgtccaac atattggcag aactttcttg aatcatcgag tgaaagaaac cacggtacga
      901 cttaaaggaa attcccactc tcaacgaggg ttagggaaaa aattgaagcg ctattggaaa
      961 ctcctacaaa aagaagaagc aaagttaaac tatgaaaaac gggtttggcg tgccagtttt
     1021 aaagattatt tgactgaaag tgagattgcc gatcgactgt tagctgcttg tcccaactta
     1081 cgccaaggct atcagttata ccaagacatt ctttatgcgg taaagaaaag agatcagtca
     1141 ctatttgagg attgtttaac tagagacatt agcggtctgc cagaaaccta tacaaccact
     1201 ttacgaacgt ttaaaaagtt tctgccacag atccaaaatg cgcttcacta cagctattca
     1261 aacggaccat tggaatgctt aaacaaccac atcaaagtat taaaacgcaa tgcgtacggc
     1321 tttcgcaact tttacaattt caaactacga attatgattc gtcatggcaa aacattttta
     1381 accaaataaa c
//
LOCUS       DADQDV010000189         1370 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.199, whole genome shotgun sequence.
ACCESSION   DADQDV010000189 DADQDV010000000
VERSION     DADQDV010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1370)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1370)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1370
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.199"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            35..1336
                     /locus_tag="J8S10_003117"
     CDS             35..1336
                     /locus_tag="J8S10_003117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAZ9631635.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT          446 a          275 c          253 g          396 t
ORIGIN      
        1 gaatcaccac aacacaatca aaggagcgtt ctgtatgcct gatcttcatc atatcaaact
       61 actacttgga atcaaagata aaaacatttt catcacaaat gtggaatcga agagcattaa
      121 gaatatcaag agtcttgttg tttctgcgac gttaagtaaa gaaattcgtc gctgtccttt
      181 gtgtaaacag atgaatcatg aaggcatgat cgttaagaac ggaaagaaaa aatcgctcat
      241 tcaacttaat aaatgtgcga accaactgac ttatcttgct ttagcgaaac aacgctacca
      301 ctgtcgtggc tgccacacct attttacggc gaatacctac attgtcgata gaaactgctt
      361 tatcgctaaa caagtgcgct ataaaatttt agaagagcta actgaaaaac aagcaatgac
      421 gacaattgct aagcattgcg gcgtttcttg gtcgaccgtt tctcggacac tcgcttctct
      481 gatccccatg acaaaagtaa aaagaaattg gttaccgcgt tgtttattaa tggatgaatt
      541 tcgttcactg aaaaatcaag tcggtcccta ctccttttct tgtatggatg gcgatactgg
      601 aaaattactg gatattcttc cttcacggaa gaaaaaggct ctcgtttctt attttatgca
      661 atttgaacga cgcgcacgat tgaaggtaaa ggtcatcgtg acggacatga atgtttctta
      721 tgcctctctg ataaaggaat gttttccaaa ggcaaaactc gttgtggatc gttttcacat
      781 tgtcaaacat ctcattcgta aatttgagga tattcgcgta cgaatcatga aaagctttga
      841 tcgaaacgat ccaacacaag ccaaatatta tcgacaatta aaggcgttgt ctcggcttct
      901 gatcaaacga caggacaagc ttgtttatga caaatggacc aaatggcgca attttggttg
      961 ggcgtatctc accgaaagtg aagtggtgga tcgtctgctt tcgatctctg acgaattacg
     1021 aatcgcctat ttttactatc aagaaattct tcaagcgttt cacgacaaag aggcggacac
     1081 tttctttaaa cttgtaagaa cgatgcccaa ttccgttcca aaagaactgc attctataaa
     1141 aaaagctttt ataaactatg aatccggcat tcgtttagcc ctcgaattgc cttattcaaa
     1201 tgccaaaata gaaaatctgc atacccacat caaagcattg aaacgagtcg cttatggctt
     1261 tcgaagcttt cggaaaatga agaccagaat tttcttacta aataatctga ttacctatga
     1321 atcaaaaaac atctaaagta gaaaaggaat tctaccttag atgttcttat
//
LOCUS       DADQDV010000190         1337 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.200, whole genome shotgun sequence.
ACCESSION   DADQDV010000190 DADQDV010000000
VERSION     DADQDV010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1337
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.200"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>1337
                     /locus_tag="J8S10_003118"
     rRNA            <1..>1337
                     /locus_tag="J8S10_003118"
                     /product="23S ribosomal RNA"
BASE COUNT          358 a          293 c          406 g          280 t
ORIGIN      
        1 gaaataatag taccgaagtt cctgatgtca cactgccgag aaaagcttct agtgagaaaa
       61 cagcggcccg taccgcaaac cgacacaggt agtcgaggag agaatcctaa ggtgagcgag
      121 agaactctcg ttaaggaact cggcaaaatg accccgtaac ttcgggagaa ggggtgctga
      181 tcatacgatc agccgcagtg aataggccca agcgactgtt tatcaaaaac acaggtctct
      241 gcaaaatcgt aagatgaagt ataggggctg acgcctgccc ggtgctggaa ggttaagagg
      301 agtgcttagc gcaagcgaag gtacgaattg aagccccagt aaacggcggc cgtaactata
      361 acggtcctaa ggtagcgaaa ttccttgtcg ggtaagttcc gacccgcacg aaaggcgtaa
      421 cgatttgggc actgtctcaa cgagagactc ggtgaaattt tagtacctgt gaagatgcag
      481 gttacccgcg acaggacgga aagaccccat ggagctttac tgtagtttga tattgagtgt
      541 ctgtaccgca tgtacaggat aggtaggagc cgtagaaatc ggaacgctag tttcgatgga
      601 ggcgctggtg ggatactacc cctgcgttat ggccactcta acccgcacca ctaatcgtgg
      661 tgggagacag tgtcagatgg gcagtttgac tggggcggtc gcctcctaaa aggtaacgga
      721 ggcgcccaaa ggttccctca gaatggttgg aaatcattcg aagagtgtaa aggcagaagg
      781 gagcttgact gcgagaccaa caagtcgagc agggacgaaa gtcgggctta gtgatccggt
      841 ggttccgcat ggaagggcca tcgctcaacg gataaaagct accctgggga taacaggctt
      901 atctccccca agagtccaca tcgacgggga ggtttggcac ctcgatgtcg gctcgtcgca
      961 tcctggggct gtagtcggtc ccaagggttg ggctgttcgc ccattaaagc ggcacgcgag
     1021 ctgggttcag aacgtcgtga gacagttcgg tccctatccg tcgcgggcgt tggaaatttg
     1081 agaggagctg tccttagtac gagaggaccg ggatggactt accgctggtg taccagttgt
     1141 tctgccaagg gcattgctgg gtagctatgt agggaaggga taaacgctga aagcatctaa
     1201 gtgtgaagcc cacctcaaga tgagatttcc catttcttta agaaagtaag atccctgaga
     1261 gatgatcagg tagataggtc aggagtggaa gtacagtgat gtatggagcg gactgatact
     1321 aatcgatcga ggactta
//
LOCUS       DADQDV010000191         1313 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.201, whole genome shotgun sequence.
ACCESSION   DADQDV010000191 DADQDV010000000
VERSION     DADQDV010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1313
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.201"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            200..742
                     /locus_tag="J8S10_003119"
     CDS             200..742
                     /locus_tag="J8S10_003119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631636.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            898..1272
                     /locus_tag="J8S10_003120"
     CDS             898..1272
                     /locus_tag="J8S10_003120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HAZ9631637.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMPDVEWQHFF"
BASE COUNT          532 a          148 c          256 g          377 t
ORIGIN      
        1 attgatgaag cagatcccaa agggctgctt catcaatttt ttcgtaagtg tccgtacact
       61 tactgtgctt gctcatatat taatcgatca tatactaatc gtgtaagaac aactttaagc
      121 ataatactta tattgttata ccatagtttg gaaaaataaa aaattatatt tcatcaacgt
      181 ttcataaaag gtgtgtagaa tgttattgaa agtagctata aaatgctatt gtgtaaaaaa
      241 taaaggagga ataatttatg aaaaaatagt accaagagga gcatgcctat tacttgcatt
      301 atgtttgagc ttaagcgcag ttgggtgtca aaaaagtaat gaaaacaata aaataaaaga
      361 aggacaatcc ataagttctg aagaggaagg catgtcaatt aatgcaaatg gcaaaaatga
      421 aacttttaag ccatcagatt atacattgga ggcaaagaaa gaatatgttt atgaatattt
      481 agggcttaaa tttaaactct cagacaaatt tagaaattat atagctgata aaaagatagc
      541 gatgttagat gatcaaagtc ctatagataa agaactaaag tatgctattt tgacatttga
      601 gaaaatgaca gaagaacaaa agaatgcagt tatagaaaag atgggcgatg gatataaaaa
      661 ttggcaaaat gagcttgaaa gaattgggac tattggtata tttgaaaaaa atacatcaga
      721 agaaaaaaat ctaaaattat aaaatgtgat actcatacta aaataggagt ttcaagtgat
      781 ggaaaatacg attgctattt aagcacaaat agcggagctg aaagtaatct tctggatgaa
      841 ttaaaaagaa ctgagattca aattatagat aaaaaagaac gtcctaaaaa tggttttgtg
      901 ctatcagaaa aaactgattt agaaaataca gaagcattta acaaagaatc ggttaaagat
      961 ttacgtaaac taccaacaaa ggacataaat ggcaaggatt ttacaagtaa agattttgag
     1021 aagtatgatc ttactatggt aaatgtattt gcaacttggt gtacagcttg tgtaaaggaa
     1081 attcctgatt tggttgaggt tcagaatgaa atgaaaagca agggtgtaaa tatcgttgga
     1141 gttgttacag atcctgttga tgataacggt gaaaacaagg aagcaattga aaagtcaaag
     1201 ttaatacatg aaaagacaaa ggcttcatat cctttcttaa tgccagatgt ggaatggcaa
     1261 cacttttttt gacaaaaatt ataaggtgtt gtgaatgctg cggtgttatg gct
//
LOCUS       DADQDV010000192         1294 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.202, whole genome shotgun sequence.
ACCESSION   DADQDV010000192 DADQDV010000000
VERSION     DADQDV010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1294
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.202"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..1244
                     /locus_tag="J8S10_003121"
     CDS             <1..1244
                     /locus_tag="J8S10_003121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HAZ9631638.1"
                     /translation="ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCL
                     THYQHTYCCKSCEKEGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQE
                     NYWKQTHGLDISRDNITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESA
                     KTDTYYWQFCTGKDSQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESV
                     RLVYCFAHVRRKFFEAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQ
                     QELRPLFIAFYEWMATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERN
                     IKELVIGRKNWLHSTSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLS
                     AETLDQLLPWNKDVQQHFSRN"
BASE COUNT          423 a          233 c          277 g          361 t
ORIGIN      
        1 ctataacaga gaaagaacat ctccttcctt tggaagaaca attttgtgaa cattgcggtt
       61 cacagatgaa agatatcgga cggacaaaag tacgagaaga aattcgtttc catcaggcta
      121 tgttggattg tctcacccat tatcaacata cctattgttg taaaagctgc gaaaaagaag
      181 gactttcttc ttttaaaaaa gcgatcgttc ctaaaccttt gatttctaat agcttaggtt
      241 ccaatagttt agtggcggaa acgatccgga tgaaatttgg tcagaaagtt cctgcctatc
      301 ggcaagagaa ctattggaaa caaacacatg ggttggatat ttcgagagat aatatcacca
      361 attggcatat taaagcagtg caaaacgcgt tagacccttt aggagaacga ttaagagtct
      421 atcttaatca agaagagatt ctacacgggg atgaaacaag ttatcgtgtg attgaaagtg
      481 ccaaaacaga tacctattac tggcagtttt gtacaggaaa agacagtcag catcccatcg
      541 tttattatca ccacgacgaa agtcgtgctg gagatgttcc gaaaactttt ctcaaggagt
      601 ttacagggta tttacactgt gacggctata gcgggtataa tgccgtggaa agtgtacgac
      661 ttgtctattg tttcgcgcat gttcggcgga aatttttcga agcaattcca aaaggaaaga
      721 aaaacacgga tattcccgca gctcaagcag tcaaacaatt ggataaatgg tttgtcctag
      781 aaaagaaatg gaaagacttt tctcctgaga agcgattaag ctgtcggcaa caagaactgc
      841 gtccattatt tattgctttt tatgagtgga tggcaacgat agatcctgtt gcaaaatcca
      901 agttggatgc agccgttcaa tatgcgtgta aactacgaag tggttttgaa cctatttttg
      961 aagatggtcg tttagaactc acaaataatc gtgcggagcg aaatatcaaa gagctggtga
     1021 taggacggaa aaattggttg cattccacaa gtcttgaagg agcacgaact tcaggaatca
     1081 ttctgagtgt atataaaaca gcagaactta acggattgaa tcctgtaaag tatctagagt
     1141 ttctatttga taagatacca aatcttcccg tactttcagc agaaacttta gatcaactgt
     1201 tgccttggaa caaggatgta caacaacatt tttctcgtaa ctaaaaacgc caaacattcc
     1261 cgattctatt ctataggtcg ggttatttga cgta
//
LOCUS       DADQDV010000193         1267 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.203, whole genome shotgun sequence.
ACCESSION   DADQDV010000193 DADQDV010000000
VERSION     DADQDV010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1267
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.203"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            66..1244
                     /locus_tag="J8S10_003122"
     CDS             66..1244
                     /locus_tag="J8S10_003122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEfm2 family transposase"
                     /protein_id="HAZ9631639.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLEE
                     TVIHLFRKGITMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKVRTLNDKYVAI
                     FMDATYIPLKRQTVSKEAIYIAIGIREDGTKEVLSYAIAPTESTYVWNELLQDIYSRG
                     VHDVLLFITDGLKGMKDTIHQIYPKAKYQHCCVHVSRNIAHKVRVKDRKEICDDFKAV
                     YQASSKEEANTFLGSMIEKWQKTYPKVTQSLIKNQDLLTFYEFPPGIRRSIYSTNLIE
                     SFNKQIKKYSRRKEQFQNEESLERFLVSIFDTYNQKFLNRSHKGFQQVTDTLASMFTE
                     "
BASE COUNT          427 a          254 c          246 g          340 t
ORIGIN      
        1 aaaaaggaag tcccttctgt agaatagagt taccacaaca cattcacaga aaagaggact
       61 tccatatgaa cgattttact acagaaattc taaagactct agcgaacaaa ggcgatttga
      121 atgaattatt ccgtgtccat ttggaaaaag ctgtcaatac gcttctcaaa acggagttaa
      181 cggctttcct cgattacgaa aagtacgatc gcattggttt taacacgggt aattctcgta
      241 acggctccta tgaccgtacg gtcaagaccg agtacgggga acttcatctc cagattccgc
      301 gcgaccgcaa cggcgagttc aagcaacaga ctgttcctgc ttatagacgg acgaatgata
      361 ccttagagga gaccgtcatt cacctcttcc gaaaaggtat taccatgtcg gaaatcgcag
      421 acttgattga gaaaatgtat gggcatcact acacgcccca aaccatgtcc aacatgacta
      481 aagtgctgac tgaagaagta aatgcattta aagttagaac tctaaatgat aagtatgtcg
      541 ctattttcat ggatgctact tatattcctt taaaacggca aaccgtctcc aaagaagcaa
      601 tctatattgc cattggtata cgagaagacg gcactaaaga agtactaagt tatgcgattg
      661 ccccgactga atcgacctac gtttggaatg agttgttaca ggacatttac tccagagggg
      721 ttcatgatgt cttactgttt attaccgatg gcttaaaagg catgaaagat acgattcacc
      781 agatttatcc taaagctaaa taccaacatt gctgtgttca cgtttcccgt aatattgctc
      841 ataaagtacg tgtcaaagat cgaaaagaaa tctgtgatga ttttaaggct gtttatcaag
      901 ctagctcaaa ggaagaggca aatacctttt tagggagtat gattgagaag tggcagaaaa
      961 cttatcctaa agtgacgcag tcactgataa aaaatcaaga tttattgact ttttatgagt
     1021 ttccgcctgg tatccgccga agcatttact caactaattt aatcgaatct ttcaataaac
     1081 aaatcaagaa atacagccgc agaaaagagc agtttcaaaa tgaagaatca ctagagcgtt
     1141 tcctagtatc catctttgat acatacaatc aaaaattctt aaatagaagc cataaaggct
     1201 tccaacaagt gacggataca ttagcttcaa tgtttactga gtaacccatt attttgcaga
     1261 aggacga
//
LOCUS       DADQDV010000194         1220 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.204, whole genome shotgun sequence.
ACCESSION   DADQDV010000194 DADQDV010000000
VERSION     DADQDV010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1220
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.204"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            49..1062
                     /locus_tag="J8S10_003123"
     CDS             49..1062
                     /locus_tag="J8S10_003123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HAZ9631640.1"
                     /translation="MESFNPELPLTLLFDYVRIRFPTTDARKIIQEILHLKFDYMLHE
                     DYAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDC
                     LKAGGVMKRLDLAINDRVGLLDIPDLTKKCQKEECISLFRTFKSYRSGELLKPDDKDG
                     MGNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAYHAIQDL
                     LKGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNQKEIQLTSEPKPY
                     TIERTLNWLGRQVAPTWKMAKELDRLNQTTYIQDMVNNTRLSDRHKKILEQQSMAIEN
                     LII"
     gene            1077..1196
                     /locus_tag="J8S10_003124"
     CDS             1077..1196
                     /locus_tag="J8S10_003124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HAZ9631641.1"
                     /translation="MEIVKDILLVFGGSMLGVTVMCLMHASAAADRAMEKKGK"
BASE COUNT          386 a          200 c          291 g          343 t
ORIGIN      
        1 ggtggcgtaa ccgcatcgac aaaaaccatg aggaaaattt ttgaccaact ggaaagtttc
       61 aatcccgagt tacctttaac gttactgttt gactatgtaa ggattcgctt tcccacaacg
      121 gatgcgagga aaatcattca agagattctc catttgaaat ttgattatat gctccacgaa
      181 gattacgcct tttactccta tcaagaacaa tatgttatgg gagatattgt ggtgatgttg
      241 tcacatgaag aagataaagg cgtcctttta gaattaaagg gtcgtggttg tcggcagttt
      301 gaaacttttt tactcgccca aaagcgtagc tggtatgact ttttcgaaga ttgtctaaaa
      361 gccggtggcg tgatgaaacg cttagacctg gcaatcaatg atcgagttgg cctgttagat
      421 attcctgatt taacgaaaaa atgtcagaag gaagaatgta tctccttgtt tcgtaccttc
      481 aaaagctatc gttccgggga actgttgaaa cctgatgata aagatggtat gggcaatact
      541 ttgtatattg gcagtcttaa gagtgaggtc tatttctgtt tgtacgaaaa agactatgag
      601 caatatatca agttagggat tcctttagac cagaccgaaa cgaaaaatcg ttttgaaatc
      661 cgactgaaaa atgatcgagc ttatcatgca attcaagatt tgttaaaagg tcgcagtatt
      721 gaaagtacca cattttccat tattaaccgg tacttgcgat ttgcggataa ggtggaaggc
      781 aaaaggcgaa ctaactggcc cttgaatgaa caatgggggc gcttcattgg acggaatcag
      841 aaggaaattc aattaacttc tgaaccgaag ccttatacca ttgaacgaac gttgaactgg
      901 cttggacgac aagtcgcccc tacgtggaag atggccaagg agttggatcg gttgaatcag
      961 acaacgtaca ttcaggatat ggtaaataat actcgactat cagaccggca caaaaagatt
     1021 ttggagcaac aaagtatggc aattgaaaat ttgattatat gaaaagagga atcgtgatgg
     1081 aaattgtgaa agatatttta ttggtgtttg gtggcagtat gcttggtgtt actgtgatgt
     1141 gcttgatgca tgcaagtgca gcggcggacc gagcaatgga aaagaaagga aagtgatgaa
     1201 atgaatttcg gtcaaaattt
//
LOCUS       DADQDV010000195         1220 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.205, whole genome shotgun sequence.
ACCESSION   DADQDV010000195 DADQDV010000000
VERSION     DADQDV010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1220
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.205"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            49..1062
                     /locus_tag="J8S10_003125"
     CDS             49..1062
                     /locus_tag="J8S10_003125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HAZ9631642.1"
                     /translation="MESFNPDLPLTLLFDYVRIRFPTTDVRKIIQEILHLKFEYMLHE
                     DYAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDC
                     LKAGGVMKRLDLAINDRVGLLDIPDLTKKCQKEECISLFRTFKSYRSGELLKADEKDG
                     MGNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAYYAIQDL
                     LKGRSIESTTFSIINRYLRFADKVDGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPY
                     TIERTLNWLGRQVAPTWKMAKELDRLNQTTYIQDMVQNARLSDRHKKILEQQSMAIEN
                     LIV"
     gene            1077..1172
                     /locus_tag="J8S10_003126"
     CDS             1077..1172
                     /locus_tag="J8S10_003126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HAZ9631643.1"
                     /translation="MEIVKDMLLVLGGSMLGVTVMCLMNASAAAD"
BASE COUNT          392 a          191 c          286 g          351 t
ORIGIN      
        1 ggtggcgtaa tcgcctctac aaagaccatg agaaaaattt ttgatcaact ggaaagtttc
       61 aatcccgatt tacctttaac gttactattt gactatgtaa ggattcgctt tcccacaacg
      121 gatgtgcgga aaattattca agaaattctc catttgaaat tcgagtatat gcttcatgaa
      181 gattacgcct tttactccta tcaagaacaa tatgtcatgg gcgatattgt agtgatgtta
      241 tctcatgaag aagataaagg tgtccttttg gaattaaaag gtcgtggttg ccggcagttt
      301 gaaacttttt tactcgccca aaagcgtagc tggtacgact tttttgaaga ttgtctaaaa
      361 gccggtggcg tgatgaaacg cttggattta gcaatcaatg atcgagtggg gctactggat
      421 attcctgatt taacgaaaaa atgtcagaag gaagaatgta tctccttgtt tcgtaccttc
      481 aaaagttacc gttccgggga actgttgaaa gctgatgaaa aggatggtat gggcaatacc
      541 ttatatattg gcagcctcaa aagcgaggtt tatttttgtt tgtacgaaaa agattatgaa
      601 caatatatca agttagggat tccattggac cagaccgaaa cgaaaaatcg ttttgagatt
      661 cggttgaaaa atgaccgtgc ttattatgcg attcaagatt tgttaaaagg tcgtagcatt
      721 gaaagtacca cgttttccat tatcaatcgg tatttgcgat ttgcggataa agtagatgga
      781 aaacggcgaa ccaattggcc cttgaatgaa caatggggtc gttttattgg acggaatcgg
      841 aaagagattc aattaacttc tgaaccgaaa ccgtatacca ttgaacgaac attaaattgg
      901 ctaggtagac aagtcgcccc tacgtggaaa atggctaagg agttggatcg attgaatcaa
      961 acaacgtata tccaggatat ggtacagaat gcgcgactct cggaccggca taaaaagatt
     1021 ttggagcaac aaagtatggc aatcgaaaac ttgattgtat gaaaagagga attttgatgg
     1081 aaattgtaaa agatatgtta ttggtacttg gtggcagtat gcttggtgtt accgtgatgt
     1141 gcttgatgaa tgcaagtgca gcagcggatt gagcaatgga aaagaaagga aagtgacaaa
     1201 atgaatttcg gacaaaattt
//
LOCUS       DADQDV010000196         1116 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.206, whole genome shotgun sequence.
ACCESSION   DADQDV010000196 DADQDV010000000
VERSION     DADQDV010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1116
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.206"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(167..240)
                     /locus_tag="J8S10_003127"
     tRNA            complement(167..240)
                     /locus_tag="J8S10_003127"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(204..206),aa:Ile,seq:cat)
     gene            complement(795..1109)
                     /locus_tag="J8S10_003128"
     CDS             complement(795..1109)
                     /locus_tag="J8S10_003128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631644.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
BASE COUNT          420 a          175 c          170 g          351 t
ORIGIN      
        1 aacttttcaa atatacagaa gtataactat gtgaaacatc ctttcattaa tccataaaag
       61 gatacataaa aaagccactc atttgagtgg caatgaagaa aagctttagc ttgtataata
      121 ctcttcaaaa aattctaaca cagaacgatt caattggcta cattaatgta ccctgtagga
      181 ctcgaaccta cgaccggacg gttatgagcc gtctgctctg accaactgag ctaagggtag
      241 tggttgttgc cacataaagc cataaacaat caaccagtag aatgcgtggc aacaaacctg
      301 ttatcgcata tcttggagtg tgactattta tgagtgatag tgaagatatg cgtctccata
      361 tatgtatggt tgagacagat aaacatgtat gaaaaacgtt gttaaatcaa cgttttttta
      421 ttttggtcaa ggagagaaaa gtagagaaat acaaaatttt ttgcattgat tttgcattca
      481 aaaaaacatt caaacattta gaaatcccca atacgtattc aggaaaatct attttaaggt
      541 ttacaaaaag aacttttgtt cgtacactct ttttgaggtg aacttttatg ctgatggaag
      601 gaaaaacaca attatggttt aagcatgttc cttcaaataa gttttttaat tataaactct
      661 agagaaatta attcatccta acataaaata attgttcact caaaagtttt tctagaacaa
      721 ttaaaacagc aggcttcaca ttcgctatac atttgtaaga agtaataatt cctgtactaa
      781 aaggcataat tgctttaatt attttttgac ttctcttcaa acacaagaag tagttgtgta
      841 ataattgcag aaataaggat tccaataata gatataaaat ttgacatgga aacgtctata
      901 acattaaaag aataaagtgt tgaagaaagt aaactgattg aaataacccc tccgtaaaaa
      961 atagtctgtg aatataccca ctttttttca gaagacgtac ttcgtttggt tctaaaacct
     1021 atccctgcat ttctactctt atcaaaaaac caaatattta gaagtaataa tattgctatt
     1081 attaagataa aattactgta aaaatccaaa agctat
//
LOCUS       DADQDV010000197         1115 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.207, whole genome shotgun sequence.
ACCESSION   DADQDV010000197 DADQDV010000000
VERSION     DADQDV010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1115)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1115)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1115
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.207"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            143..400
                     /locus_tag="J8S10_003129"
     CDS             143..400
                     /locus_tag="J8S10_003129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631645.1"
                     /translation="MSNLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEKELDKEFKEINDLLL"
     gene            complement(632..1045)
                     /locus_tag="J8S10_003130"
     CDS             complement(632..1045)
                     /locus_tag="J8S10_003130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014834562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HAZ9631646.1"
                     /translation="MDQKAFIESIDSTIDRLKKEIRFYNRVIGIGNIIKIVLSASIPI
                     LIDQASEHRSLLLIVSIASAIITIIQSGMSAFNYQDKVQTSTELLMKIEKEKLLYITK
                     TSPYNKTDEENFHLIVTTLQTELNDIISDFNQVNN"
BASE COUNT          422 a          141 c          144 g          408 t
ORIGIN      
        1 ttttctgtcc acgttcattt tactccaaag ttttcctcat ttcaaaagaa aatcacagaa
       61 tacacgaaga agcgtttcta tttgtataaa ctatatcaaa gttctatact taaattatca
      121 aataaaaagg acgtgaagat aaatgtcaaa tttagaaaac aaagaagaaa aagttgtaaa
      181 caaaattgtt tctgttgtca ataaactgga taaagagtta gacgaacttg atacgttatc
      241 tgaaaatcca gaaaaaaaac ataacctaaa aaaatggtta gttgaacgaa aggctattca
      301 tgaaattaaa aaagttcttc atgaagctga taaatatgaa aaatatgatg aaaaagaact
      361 tgataaagaa tttaaagaaa tcaatgactt attactataa ttgatttata cgactcattt
      421 ttgagtcgtc agactgcaaa caacactcta aatttaggag tttgtctaca gtctgaatag
      481 attttaaatt tattgtccat aatgttatta tgaatttata gcattaagaa aagagataag
      541 actttacatt tttttaggaa tgtaaagtct tatctctttt cttaattgta caattagtat
      601 tatctgcact actttctaat taaataaatt tttagttatt aacttgatta aaatcagaga
      661 taatatcatt taattcagtt tgaagggttg taacgattaa atggaaattt tcttcatctg
      721 ttttattata tggggatgtt ttcgttatat ataacaactt ttctttttca attttcatta
      781 ataactctgt cgaagtctgt actttatctt gataattaaa tgcagacata ccactttgta
      841 taattgtaat tattgctgaa gcaattgaaa caatcaatag taaagacctg tgttcggaag
      901 cctgatcaat taatattggg atactagctg ataagactat ttttataata tttccgatac
      961 caattactct attataaaat cgaatttctt tttttaatct atcgattgta gaatcaatag
     1021 attcgataaa cgctttttga tccatcattt tctctccaat cattttatta aaatcattaa
     1081 caaaaatatt ataataggat ttaagtaagt tctaa
//
LOCUS       DADQDV010000198         1112 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.208, whole genome shotgun sequence.
ACCESSION   DADQDV010000198 DADQDV010000000
VERSION     DADQDV010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1112)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1112)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1112
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.208"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(267..971)
                     /locus_tag="J8S10_003131"
     CDS             complement(267..971)
                     /locus_tag="J8S10_003131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631647.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
BASE COUNT          321 a          194 c          199 g          398 t
ORIGIN      
        1 cttttttctc tatcagaaaa tatgtttatt attagaattt tttatagtta aggttaggca
       61 tcttaagaaa tcaggcaact ccaagatatc ttcaggtaga agagaagtcg cctaacattg
      121 taggatcata ggtgatttgt tggacaggtc aagctgatat ttgagcctga tgttagaagg
      181 aatttctttt tacttgctgt agaaattatt atatgactaa aaaggctggg attttaaatc
      241 ccagcctttt atgacaaata gaatttttat cgatcagtaa tcgctgtcgc tgcaaattgt
      301 tcgatcaaag gaatcaaagt caatttgact ttgtatttcc gttcgagtgc tttttcgata
      361 acgaactcat tttcagtagt catagaaata gttgctaatt tacgaggttc atcagcattt
      421 ttttcattaa taactacttc atgttcattt tgttctgtgt aaaatttagg atactcagca
      481 acggcttttg aaaaatcagc aaaacttaaa gcggcattcg tatcagttga gcgtgtattt
      541 tcagttgtgt ccgcttttgg tttttccgtt ttttcttctg gcacactgac tgtttcttct
      601 gtaactggtg tcgcaacagc ttgcgcagtt ggttcatcgt ttttcaatcg ttgatcattc
      661 cagtaagaca cgatttcaat aagaagattg tcacggaatc gttcgaaaat cccgttttct
      721 cctgaacgaa ttctctttaa tacagtattg aagttgtcat cgattggcac gttgatccgt
      781 gtatcttcat ttgttttccc agctaatccg atcgttaaga tttgacggtt tttgggatca
      841 agcatgactt gtaacggcaa accataacgt cgcaagctct cttcttctag agaacggaat
      901 aattgtcctc ttacaccatc caatgaagga cggaattgat ttaataattt ttgtttctgt
      961 tttttcttca tatgttctct ccttcgctca taccctttcg attataagaa aaaaacagcc
     1021 aaatgaaaag gagtaatgca aaaaaacttg cgtatacgca aattacaaca gaaaaatttg
     1081 cgtattttcc cgttttttga aagaaaaata aa
//
LOCUS       DADQDV010000199         1107 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.209, whole genome shotgun sequence.
ACCESSION   DADQDV010000199 DADQDV010000000
VERSION     DADQDV010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1107
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.209"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(1..254)
                     /locus_tag="J8S10_003132"
                     /pseudo
     CDS             complement(1..254)
                     /locus_tag="J8S10_003132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
     gene            complement(286..447)
                     /locus_tag="J8S10_003133"
     CDS             complement(286..447)
                     /locus_tag="J8S10_003133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631648.1"
                     /translation="MAYMVARTQKHKVGSLNGLQNHVDRKTKNHTNKDIDITKSGSVA
                     KFSKKSILV"
     gene            complement(771..1103)
                     /locus_tag="J8S10_003134"
     CDS             complement(771..1103)
                     /locus_tag="J8S10_003134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631649.1"
                     /translation="MNNREILAKEMADLKAKEAKIRAKRKQIRQKEMISLAKLYCKKE
                     GFKTPAEALDFLESNKRNHSVNDEVLVSLRKFADGLVWQENGAYWRTNDVKGLTQFMA
                     QFRSENVN"
BASE COUNT          312 a          238 c          146 g          411 t
ORIGIN      
        1 gtcccttaat tttgatatag gtttcgtcca ttttccatga atagaaggat tgtctatttt
       61 tcttcttcca aagataatcg aggactttgc tgtactcttg cacccaacga taaatcgtag
      121 tatgacaaac atttattcca cgatcatata acaattcctg aacttcacga tagcttagat
      181 tgtaacgcag gtagtaacta acagcgacaa taatgacgtc attttttgaa ttgtttgcct
      241 ttaaaatgat tcattactct atcctctctg tcttttttct caattttaca ctaaaataga
      301 ttttttggaa aactttgcaa cagaaccact tttcgtaata tcaatgtctt tattcgtatg
      361 atttttcgtt ttacgatcta catgattttg aagtccattt aacgacccaa ctttatgctt
      421 ttgtgttcgt gccaccatat aggccataac tgtgtacttc ctttcgttaa aattattgcg
      481 agaatcacaa gctaaattcg gaaaaacctc catgtaaggt ataacttact agacttatac
      541 tgcgtaaagt ctgtaagctc tgccgagggc tatatcggct taacagccga tgagaaactc
      601 cgtttctctc aaacgaaaaa gcgaacgaaa aacgactgcc ttcgcattcc ttttttacgt
      661 ccttttttcg ttcaaaacca ttggcttttt gcgtcattgt tttcacaatt tttattccgc
      721 aaaaaaccaa aagtgaaaag tattgctttt cacttcaacc cctcctcaat ttagttcaca
      781 ttttctgaac gaaattgtgc cataaattga gtcaaaccct taacatcatt cgtacgccaa
      841 tatgcaccat tttcttgcca aactaatcca tctgcaaatt ttcttagcga tactaaaacc
      901 tcatcattta ctgaatgatt tcttttattt gattccaaaa aatctaatgc ttcagcaggt
      961 gtcttaaagc cttccttttt acaatataat ttcgctaaag aaatcatttc tttctgtcta
     1021 atctgttttc gtttcgctct aatcttcgct tcttttgctt tcaaatccgc catttctttt
     1081 gccaatattt ctctattgtt cattttg
//
LOCUS       DADQDV010000200         1073 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.210, whole genome shotgun sequence.
ACCESSION   DADQDV010000200 DADQDV010000000
VERSION     DADQDV010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1073
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.210"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..438
                     /locus_tag="J8S10_003135"
     CDS             <1..438
                     /locus_tag="J8S10_003135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631650.1"
                     /translation="MLLGNFEQGNRVYEITGTAPTLSTKQGGTKIMLRKNETEYQEVK
                     PGNSVNLAFPNSTSRRGRLGKQSVHTLLTGDQQAVVTDQYQIRKLTPRECWRLQGFPD
                     WAFDRASQVNSDSQLYKQAGNSVTVPVIFDIARRLKEVKTDDL"
     gene            463..717
                     /locus_tag="J8S10_003136"
     CDS             463..717
                     /locus_tag="J8S10_003136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631651.1"
                     /translation="MIGKIQSDPELEEELYRLNFDIRKNGVKVPDDPYVIDEETDARM
                     ELNQVISELERIADFAKEPDIRQYLFEIKAELEIEGITAE"
BASE COUNT          342 a          192 c          274 g          265 t
ORIGIN      
        1 atgttactgg gaaattttga acaaggcaat cgggtttatg agataactgg aacagcgcct
       61 actttgtcaa cgaaacaagg cggaacgaag atcatgcttc ggaaaaacga aacagaatat
      121 caagaggtga agccagggaa cagtgtgaac ctggcttttc ctaattccac aagtcgtcga
      181 ggccgtctgg gaaaacaaag tgtgcatacc ttattaacag gagaccaaca agcagtcgtc
      241 acggatcagt atcaaattcg aaagttaaca cctagggagt gctggcggct tcagggcttt
      301 ccggactggg cttttgatcg agcttctcaa gtcaattcag atagtcagtt gtataagcag
      361 gctggaaatt ctgtaacagt tccggtcatt tttgatattg ctagaagatt aaaggaggta
      421 aaaacagatg atttatgatg agttgattgg ggaatctact gggtgattgg caagattcag
      481 tcagatccgg aattggaaga agaactgtac cggctcaatt ttgatattcg caaaaacggg
      541 gtgaaagtcc ctgatgatcc gtatgtaatt gatgaggaaa cggatgctcg aatggagctg
      601 aatcaagtca tcagtgaatt ggaacgaatt gcggactttg ctaaagaacc tgatatccgc
      661 caatacttgt ttgagataaa agcagagttg gaaattgagg gtattaccgc ggagtaacgg
      721 ccaaataaac cactgatagg cactgaccgc gggggatttg cgaagcagaa atcctccgtg
      781 gtgctgtgcc tgtttatgga cggcgttagc cggccatgat gtctcacccc ccgtatctaa
      841 caggggggta caaaaacaca aaaaataagc aagcaacgat aaggaatggc tgtcctatca
      901 aggataataa gcaatttgtg tagatgttaa ctgatttgaa aaagttaaca ccttaaattt
      961 ggaggtgaga acttggcaca aaggaattta gattatcggc tattaaaaga ccggcgtaat
     1021 gaatatggcg tttcacaaaa taaattagct acgacttgtg gacttagtcg ccc
//
LOCUS       DADQDV010000201         1073 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.211, whole genome shotgun sequence.
ACCESSION   DADQDV010000201 DADQDV010000000
VERSION     DADQDV010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1073
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.211"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            2..>1073
                     /locus_tag="J8S10_003137"
     rRNA            2..>1073
                     /locus_tag="J8S10_003137"
                     /product="23S ribosomal RNA"
BASE COUNT          329 a          214 c          308 g          222 t
ORIGIN      
        1 attgtgtgaa tacatagcac attcgaggta gacgcagaga actgaaacat ctaagtacct
       61 gcaggaagag aaagaaaatt cgattccctg agtagcggcg agcgaaacgg gaaaagccca
      121 aaccagcaag cttgcttgtt ggggttgtag gactccaata tggtagttct ttcagatagt
      181 cgaatgactt ggaaaagtca gtcaaagagg gtaaaaaccc cgtagacgaa atgtggaaga
      241 cacctaggag gatcctgagt acggcggaac acgagaaatt ccgtcggaat ccgggaggac
      301 catctcccaa ggctaaatac tccctagtga ccgatagtga accagtaccg tgagggaaag
      361 gtgaaaagca ccccggaagg ggagtgaaat agaacctgaa accgtgtgcc tacaacaagt
      421 caaagcccgt taatgggtga tggcgtgcct tttgtagaat gaaccggcga gttacgattg
      481 catgcgaggt taagttgaag agacggagcc gcagcgaaag cgagtctgaa tagggcgttt
      541 gagtatgtag tcgtagaccc gaaaccatgt gatctaccca tgtccaggtt gaaggtgcgg
      601 taaaacgcac tggaggaccg aacccacgta cgttgaaaag tgcggggatg aggtgtgggt
      661 agcggagaaa ttccaaacga acttggagat agctggttct ctccgaaata gctttagggc
      721 tagcctcgga attgagaatg atggaggtag agcactgttt ggactagggg cccatctcgg
      781 gttaccgaat tcagataaac tccgaatgcc attcattcat atccgggagt cagactgtga
      841 gtgataagat ccatagtcga aagggaaaca gcccagacca ccagctaagg tcccaaaata
      901 tatgttaagt ggaaaaggat gtggggttgc acagacaact aggatgttgg cttagaagca
      961 gccaccattt aaagagtgcg taatagctca ctagtcgagt gaccctgcgc cgaaaatgta
     1021 ccggggctaa acatattacc gaagctgtgg agtacacctt taggtgtatt ggt
//
LOCUS       DADQDV010000202         1069 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.213, whole genome shotgun sequence.
ACCESSION   DADQDV010000202 DADQDV010000000
VERSION     DADQDV010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1069)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1069)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1069
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.213"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..969
                     /locus_tag="J8S10_003138"
     CDS             <1..969
                     /locus_tag="J8S10_003138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAZ9631652.1"
                     /translation="PINTFAYTINDEYNLAPNQGDSRLAIPNKIILHETGIDAPARNV
                     AANMKNNYNGSNSYTTDVIGDGGIVYRVGEQGYVSWGAGNANPYAPVQIELQRTYDKA
                     LFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIISHLWVTNYVWGNHTDPYGYL
                     SQMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAANPTLTDGTNHAHIDQFGE
                     IENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIYRPDVNQAYNTSGNVGYH
                     VSFNMRNFPSKKVYVMMRATNDPEGNTKGGAQDFHDKRWYLNIPKR"
BASE COUNT          368 a          185 c          214 g          302 t
ORIGIN      
        1 cccattaata cgtttgctta tactattaat gacgagtata atttagcgcc gaatcaagga
       61 gactccagat tagcaattcc taacaaaatt attttgcacg aaactggaat agatgcacca
      121 gcaagaaacg tagccgccaa catgaaaaat aattataacg gaagcaattc ttatactaca
      181 gatgttattg gtgacggtgg gattgtttac cgtgtgggtg agcaaggata tgtttcgtgg
      241 ggagctggta acgctaatcc ttatgcgcct gtacagattg aattacagcg cacatatgat
      301 aaagcattgt ttgaaaaaaa ctatcgagct tatattgaat atacaagaga tagtgcaaaa
      361 aaatatggaa ttccattgac tcttgatcaa ggaacttctt tatttacaaa aggaatcatt
      421 tctcatttgt gggtgacaaa ttatgtttgg gggaaccaca cagatccata tggttactta
      481 tcgcaaatgg gagttagcaa agaaaagctt gcttatgatt tagctcatgg atttaccgat
      541 gaaaatccaa caacttctga aaacaagcct gtcattgatc caacacgagc tggtgcagct
      601 aatcctacgc tgacagatgg aacaaatcac gcccacattg atcagtttgg ggaaatcgaa
      661 aacgcaaact tgcatgtggc tggatggcac attgctaact ataaatacga gtatattttc
      721 attatggact acaatactgg gaaagaatta gctcgagtaa gagctgatgg aatttataga
      781 ccagatgtaa accaagctta taatacttct ggaaatgttg gttatcatgt atctttcaat
      841 atgcgtaatt ttcctagtaa gaaagtctat gtaatgatgc gggcaacgaa tgatccagag
      901 ggaaacacta aaggcggtgc gcaagatttc catgacaaac gttggtattt aaatattcct
      961 aaacgataaa aatagctcct cgttgaggag cagtacataa ctatattgac aactataaaa
     1021 attattcgat aaaatagtga tgttatcgca tatcttcact atcacccat
//
LOCUS       DADQDV010000203         1063 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.214, whole genome shotgun sequence.
ACCESSION   DADQDV010000203 DADQDV010000000
VERSION     DADQDV010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1063)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1063)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1063
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.214"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(38..994)
                     /locus_tag="J8S10_003139"
     CDS             complement(38..994)
                     /locus_tag="J8S10_003139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631653.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
BASE COUNT          346 a          177 c          160 g          380 t
ORIGIN      
        1 tttagaaaaa gcagtcggac tttctaaaag aagttcacta ttcgatcctg tcgatgattt
       61 cttcaggaaa atcgtctatt tgcttgtcaa ttttgctgtc tttgtatttc tcttcttgga
      121 tagtcaacaa aatctttgta agattccccc agtctactgc tcttggcgga tcgagccaaa
      181 ccactacttg agatgcactt tcttcatata gattattcct attcgtgatt ataacatccg
      241 ggaactcagg ctttcctgcc tctatcactt ccgtgttcag attaatgtac aagcttaaat
      301 ttttcttgat aaattgatta taggcagcac cataagaaaa atcgatgatg atctttactg
      361 gttcagaaat cagttgaatg ggtatgtgat tgatcaataa taataaataa ctgaaaaaaa
      421 gaaaaaattt atcttgaagc aactctttgc gttttgacgt tagatcattt atatactcta
      481 tcaaatagca ataaaatgct ggatagtttt ctctaaaaaa agaaacatca agtggaaatt
      541 catcagcttt attaatagtg taatgcaaaa gtttaaaatg tattttggtt aactctcttc
      601 ggatcaattg gctcgtctct tctcgcaaca gattaaactg attttcaaaa ctttcaatga
      661 atcgttcatt caaccattcg attgtttcat cttcattttt tctcaagtat ttttgatcca
      721 atttatcatg aagataaagc caagagagtg tcttattgat aaaaataacg gatttttctc
      781 ctaatactcc ttttaagtgg taaaatccta tatccgaaaa aaatagcgac tgattgctag
      841 caatatctaa agaatcagct tgttcagcca acaggttgat tgctaaaaag tggaataatt
      901 tctttttttc ataagcagac agaggataat actgttttaa atcttttaac attttttctg
      961 tttttataat tataggtagc gtatacaatt ccacaaaact tatctctgtt gagttaaaaa
     1021 gattatataa aaaaagccga atgtttttag gattccctgt caa
//
LOCUS       DADQDV010000204         1062 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.215, whole genome shotgun sequence.
ACCESSION   DADQDV010000204 DADQDV010000000
VERSION     DADQDV010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1062
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.215"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            4..963
                     /locus_tag="J8S10_003140"
     CDS             4..963
                     /locus_tag="J8S10_003140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016249812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAZ9631654.1"
                     /translation="MNGFAYTINNEFNLGANEGSSQVANNQYILLHETANETATGRNE
                     AQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGSYANANSPVQIELQHTHDKAT
                     FEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHLWVTQNIWGDHTDPYGYLSEM
                     GVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAANPTLTDGTNYAHIDQFGEIEN
                     ANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIYRADVNQAYNTSGNVGYHVSF
                     NMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYLNIPKR"
BASE COUNT          366 a          195 c          213 g          288 t
ORIGIN      
        1 ccaattaacg gatttgccta tactatcaac aatgaattta atttgggcgc aaatgaaggt
       61 agctcacaag tagcaaataa tcagtatatt ttactgcatg aaacggctaa tgaaacagca
      121 acaggacgca atgaagcgca gtatatgcaa cgttcatgga ctagcgctta tactgcttat
      181 attgtgggag acggcggaat tgtttatcaa gtcggtcaac ctggttatgt acagtacggt
      241 gctggttcgt atgctaatgc caacagtcct gtgcagattg agttacaaca cacacatgat
      301 aaagcaacgt ttgagaaaaa ctacaaggca tacgttgaat tggctagaga ttcagcaatg
      361 aaatatggta ttccattaac gttggacact ccttataacc aaccgggaat caaatcgcat
      421 ttatgggtaa cacaaaacat ctggggcgat catacagatc cttacggtta tctttctgaa
      481 atgggcgtaa gtaaagaaaa attagcatat gatttagctc atggatttac cgatgaaaat
      541 ccaacaactt ctgaaaacaa gcctgtcatt gatccaacac gagctggtgc agctaatcct
      601 acactgacag atggaacgaa ttacgcccac attgatcagt ttggagaaat cgaaaatgca
      661 aatttgcatg tagctggatg gcacattgct aactataaat acgagtatat cttcattatg
      721 gattacaata ctgggaaaga attagctcga gtaagagctg atggaattta tagagcagat
      781 gtaaatcaag cttataatac ttctggaaat gttggctatc atgtatcttt taacatgcgt
      841 aacttcccta ataagaaagt ctatgtcatg atgcgggcaa cgaatgatcc agagggaaac
      901 actaaaggcg gtgcgcaaga tttccatgac aaacgttggt atttaaatat tcctaaacga
      961 taaaaatagc tcctcgttga ggagcattac ataactatat tgacaactat aaaaatcatt
     1021 cgataaaata gtgatgttat cgcatatctt cactatcacc ca
//
LOCUS       DADQDV010000205         1048 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.216, whole genome shotgun sequence.
ACCESSION   DADQDV010000205 DADQDV010000000
VERSION     DADQDV010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1048)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1048)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1048
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.216"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            12..506
                     /locus_tag="J8S10_003141"
     CDS             12..506
                     /locus_tag="J8S10_003141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631655.1"
                     /translation="MADIVQLKEDGVAKYLKTHVEAIDGKEALVQTDGDQAIAGHKNF
                     SGSVTINNKRVLTTDDNRYEVVNLVVTNGNTGTAKLYREGKTVSIYFVALNGKSSGGN
                     DSVILTVPEGYRTPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYGSAYSFVI
                     TYSI"
     gene            520..951
                     /locus_tag="J8S10_003142"
     CDS             520..951
                     /locus_tag="J8S10_003142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631656.1"
                     /translation="MKVVYKSIKPYGFEQIILNNQENIPENCTEIKPPVPNWRPRFDF
                     DKKQWVELATEEEKKGNAVDSVDELANIKALYETLKAENDELKQLNSKAMLNNVAIKQ
                     ENVLLKEKSESLAQLNSKTMLASVQNTKEIEEIKKQLQGGK"
     gene            953..>1048
                     /locus_tag="J8S10_003143"
     CDS             953..>1048
                     /locus_tag="J8S10_003143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HAZ9631657.1"
                     /translation="MYSYEDIKLMYDWGCFTNEQVMVFVPLCITEE"
BASE COUNT          388 a          150 c          227 g          283 t
ORIGIN      
        1 gggacggttt aatggctgat attgtgcaat taaaagaaga cggagttgct aaatacttaa
       61 aaacgcatgt agaagctatt gatggtaaag aagcattggt gcagacagat ggagaccaag
      121 ccattgcagg acataagaat ttttcaggtt ctgtaacaat caataataaa cgtgttttga
      181 cgactgatga taacagatat gaagtggtaa atctggttgt cactaacggt aatacaggga
      241 cagcaaagct ttatcgtgaa ggaaaaacag tttctatata ttttgtggct ttaaacggaa
      301 aaagtagtgg cgggaatgat tcggttattt taactgttcc agaaggctat cggacaccaa
      361 ttagttttga acaactggtt gggtcaatag accgttctac tttgaacagt gctcaactat
      421 ctattggcgc agacggagcc attaaatgga gaagaaattc aagttatgga tcagcttatt
      481 catttgttat cacttattca atttaaggga ggaaatctaa tgaaagtagt ttacaaatca
      541 atcaagcctt acggattcga gcaaatcatt ttgaacaatc aagaaaatat ccctgaaaac
      601 tgtacagaga ttaaaccacc agttcctaac tggagaccaa gatttgattt tgataaaaaa
      661 cagtgggttg agttagctac tgaagaagag aaaaaaggga atgctgttga tagcgtagat
      721 gaattggcta atattaaggc attatacgaa acgctgaagg cagaaaatga tgaattgaaa
      781 cagctaaatt ctaaagcaat gctaaacaat gtagcaatca agcaagaaaa tgtcttattg
      841 aaagaaaagt cagaaagttt agcgcagttg aattcaaaaa cgatgcttgc ttctgtacaa
      901 aataccaagg aaatcgaaga aatcaaaaaa caattacaag gtgggaagta acatgtattc
      961 atatgaagat atcaaactaa tgtatgactg gggctgtttc actaacgaac aagtaatggt
     1021 tttcgttccg ttgtgcatta ctgaagaa
//
LOCUS       DADQDV010000206         1044 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.217, whole genome shotgun sequence.
ACCESSION   DADQDV010000206 DADQDV010000000
VERSION     DADQDV010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1044)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1044)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1044
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.217"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            5..979
                     /locus_tag="J8S10_003144"
     CDS             5..979
                     /locus_tag="J8S10_003144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase family protein"
                     /protein_id="HAZ9631658.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGEAKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          375 a          132 c          182 g          355 t
ORIGIN      
        1 aactatgtgt acgtctatta cttatgtaac aagtgatcat tattttggaa ggaattttga
       61 ttatgaaata tcttacaatg aagtagttac tgttactcca agaaattata agttgaattt
      121 tcgaaaggta aatgatttgg atactcatta tgcaatgatt ggtattgccg ctggtatagc
      181 tgactaccct ctttattacg atgcgacaaa tgaaaaagga ttgagtatgg ctgggctaaa
      241 tttttctggg tatgctgatt ataaagaaat acaagaaggg aaagacaatg tatctccttt
      301 tgaatttatt ccttggattt taggacaatg ctcaacagta ggagaagcta aaaaattgtt
      361 aaaaaatatc aatttagcaa atataaatta tagtgacgaa cttcctttat cccctttaca
      421 ttggctatta gctgataaag aaaaatcaat tgtcattgaa agtatgaaag atggacttca
      481 tatatatgat aaccctgtgg gcgttcttac caataatcct tcatttgact atcaattatt
      541 taatttaaac aattatcgtg tcttatcgag tgaaactcct aaaaataatt tttcaaatca
      601 aataagtttg aatgcctata gccgcggtat gggagggata ggcttgcctg gagatttatc
      661 ctcagtatct cgttttgtta aagcgacttt tacgaagctg aattctgtat ctggagattc
      721 agagtcagaa agtattagtc aatttttcca tatcttaggt tcagtagaac aacaaaaagg
      781 tttgtgtgat gtaggtgatg gaaaatatga atatacaatt tattcttctt gttgcaatgt
      841 tgacaaagga atctattatt atcgaacata tgaagacagt caaattactg caattgatat
      901 gaataaagaa gacttagata gtcataagtt aattagttat ccaattatag aaaaacaaca
      961 aattaaatat ataaattagt taatgtgttg tgattgatta tttaatatag atataataca
     1021 aaaaggcaaa gatattttca aaac
//
LOCUS       DADQDV010000207         1035 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.218, whole genome shotgun sequence.
ACCESSION   DADQDV010000207 DADQDV010000000
VERSION     DADQDV010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1035
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.218"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..>1035)
                     /locus_tag="J8S10_003145"
     rRNA            complement(<1..>1035)
                     /locus_tag="J8S10_003145"
                     /product="16S ribosomal RNA"
BASE COUNT          218 a          324 c          234 g          259 t
ORIGIN      
        1 agcacgtgtg tagcccaggt cataaggggc atgatgattt gacgtcatcc ccaccttcct
       61 ccggtttgtc accggcagtc ttgctagagt gcccaactga atgatggcaa ctaacaataa
      121 gggttgcgct cgttgcggga cttaacccaa catctcacga cacgagctga cgacaaccat
      181 gcaccacctg tcactttgcc cccgaagggg aagctctatc tctagagtgg tcaaaggatg
      241 tcaagacctg gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc caccgcttgt
      301 gcgggccccc gtcaattcct ttgagtttca accttgcggt cgtactcccc aggcggagtg
      361 cttaatgcgt tagctgcagc actgaagggc ggaaaccctc caacacttag cactcatcgt
      421 ttacggcgtg gactaccagg gtatctaatc ctgtttgctc cccacgcttt cgagcctcag
      481 cgtcagttac agaccagaga gccgccttcg ccactggtgt tcctccatat atctacgcat
      541 ttcaccgcta cacatggaat tccactctcc tcttctgcac tcaagtctcc cagtttccaa
      601 tgaccctccc cggttgagcc gggggctttc acatcagact taagaaaccg cctgcgctcg
      661 ctttacgccc aataaatccg gacaacgctt gccacctacg tattaccgcg gctgctggca
      721 cgtagttagc cgtggctttc tggttagata ccgtcaaggg atgaacagtt actctcatcc
      781 ttgttcttct ctaacaacag agttttacga tccgaaaacc ttcttcactc acgcggcgtt
      841 gctcggtcag actttcgtcc attgccgaag attccctact gctgcctccc gtaggagttt
      901 gggccgtgtc tcagtcccaa tgtggccgat caccctctca ggtcggctat gcatcgtggc
      961 cttggtgagc cgttacctca ccaactagct aatgcaccgc gggtccatcc atcagcgaca
     1021 cccgaaagcg ccttt
//
LOCUS       DADQDV010000208         1003 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.219, whole genome shotgun sequence.
ACCESSION   DADQDV010000208 DADQDV010000000
VERSION     DADQDV010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1003
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.219"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..159
                     /locus_tag="J8S10_003146"
     CDS             <1..159
                     /locus_tag="J8S10_003146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HAZ9631659.1"
                     /translation="RRNKFYRSLRTASSTIKGMETIRGIYKKNRRNGTLFGFSVSTEI
                     KVLMGIPA"
     gene            242..859
                     /locus_tag="J8S10_003147"
     CDS             242..859
                     /locus_tag="J8S10_003147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011834674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631660.1"
                     /translation="MWIFKQEIFAKLFSLDGLGWGILFFIFLFLGSMWIWFVDKKNSY
                     EKVIVKKMNRNEFDDFSKEHRVELYDSHEINSTSPSYYWVFGCEEKPLEIKLLKMLEN
                     PPVIEDFSAKNVEKQMFEQVQIRGQNKISLEPDEYAAFFLETNSGTSMPVFKVKLKMN
                     GRLCTYDLVANMRYGSTGDRRTILKFEQTFRSFLKNRVSQIFNLD"
BASE COUNT          342 a          126 c          187 g          348 t
ORIGIN      
        1 cgacggaata aattttatcg aagtctccgg actgcctcat ccacgattaa ggggatggag
       61 accattcgag gaatatataa aaagaaccga agaaatggaa cgctcttcgg cttttcggtg
      121 tctactgaga tcaaggtatt aatgggaata ccagcctaag atatttggag ttcagagagg
      181 gcgcgtttga ttttcaaact tcgcaacaga accattattt taaagtggga ggaaaattgt
      241 tttgtggata tttaaacaag aaatctttgc taaattattt agtttagatg gattaggttg
      301 gggaatctta ttttttattt ttttattttt aggatctatg tggatctggt ttgttgataa
      361 aaaaaattct tatgagaaag taatagtgaa aaaaatgaat cgaaatgaat tcgatgattt
      421 ttcaaaggaa catagagttg aattgtacga tagtcatgaa attaacagta cttctccatc
      481 ttattattgg gtatttggtt gcgaagaaaa accattggag attaaattgt tgaaaatgct
      541 tgaaaatcct ccagtcattg aagatttttc tgcaaaaaac gttgaaaaac agatgtttga
      601 acaggtacaa ataagaggtc aaaacaaaat ttcattagaa ccagatgaat atgcagcctt
      661 ttttttagaa acaaattcag gtacttcaat gcctgttttc aaagttaaat taaaaatgaa
      721 tggtcgttta tgcacttatg atcttgttgc aaatatgcgc tatggttcta ctggtgatag
      781 acgtactatt ttaaaatttg agcaaacctt tagaagtttt ttgaaaaata gagtatccca
      841 aatttttaat ttggattgaa aaaattaaaa atttggccaa aaatactaca gttttttaga
      901 gcaatcatct tatgatgatt gctctttttt tgttgttttt gtgtcattcg ttgttcaaat
      961 cctctattcg taaaataaat attttaaact agaaatatgc ctt
//
LOCUS       DADQDV010000209         1003 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.220, whole genome shotgun sequence.
ACCESSION   DADQDV010000209 DADQDV010000000
VERSION     DADQDV010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1003
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.220"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>1003
                     /locus_tag="J8S10_003148"
     CDS             <1..>1003
                     /locus_tag="J8S10_003148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAZ9631661.1"
                     /translation="GKKISMILLNRSGNKRTYLRLKKQRYLCRACKKYFTARTYLVTP
                     FCFISKQIHYKILEELTERQSIKAIGKHCDVSVTTVQRTLSALSSDIRQNLEYLPRCL
                     LFDEFRSLSTWHGKFSFSCMDGETGKLFEILPSRRKKDLVAFFMRFSLKARLGVHYIV
                     TDMNAPYFSLVKECFPNAQVIVDRFHIVQHLNRFFDAVRKRVMKTLDQKDPIQAKQYR
                     QLKSLFKLLLKSEDRLDYNTLTKRRNFNWRLLTETEVVDRLLKISPELKTAYRYYQDL
                     LTAYQEKDPDTFFQLLRAMPGEVPLELHHIKKAFFKYEKGIRLALLKKYSNARLENLH
                     "
BASE COUNT          300 a          209 c          191 g          303 t
ORIGIN      
        1 tggcaagaag atctctatga ttctcctgaa tcgtagcggt aataaacgga cctatcttcg
       61 gttgaagaaa cagcgatacc tctgccgagc atgtaaaaaa tattttaccg ctcggacgta
      121 tctcgttacc ccattctgct ttatttctaa gcagattcat tacaagatct tagaagaatt
      181 gacagagcgt caatctataa aagcaattgg taaacattgc gatgtttctg tgacaactgt
      241 tcagcggaca ttgtccgcct tgtcatcaga tatccgtcag aatcttgagt atttacctcg
      301 gtgtctatta ttcgatgagt ttcgttctct ttctacatgg cacggtaaat tttctttttc
      361 ttgtatggac ggtgagaccg ggaaactgtt tgagatctta cctagccgcc gtaaaaaaga
      421 tctcgttgct tttttcatgc gtttttctct caaagcgagg ttgggtgtac attacatcgt
      481 aacggatatg aacgctcctt atttctcact agttaaagag tgttttccaa atgcacaagt
      541 gatcgtcgat cggtttcaca ttgttcaaca tctgaaccgc ttcttcgatg cggttcgaaa
      601 acgtgtgatg aaaacacttg atcaaaaaga cccaatacaa gctaaacagt atcgccaatt
      661 gaaatcctta ttcaaattac ttttaaaatc agaggatcgt ttagattaca atacactaac
      721 gaaaagacgc aatttcaatt ggagactatt gactgaaaca gaagtagttg accgccttct
      781 aaagatttct cctgaactta aaacagctta tcgttactac caagacctgc ttactgcgta
      841 tcaggaaaaa gatccagata cttttttcca gctgcttcga gcaatgcctg gagaagttcc
      901 attggaactg caccatatca aaaaagcctt tttcaaatac gagaaaggga ttcggctggc
      961 attactgaag aagtattcga atgcacgact ggaaaatctc cat
//
LOCUS       DADQDV010000210         1001 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.221, whole genome shotgun sequence.
ACCESSION   DADQDV010000210 DADQDV010000000
VERSION     DADQDV010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1001
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.221"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            370..1001
                     /locus_tag="J8S10_003149"
                     /pseudo
     CDS             370..1001
                     /locus_tag="J8S10_003149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          342 a          181 c          184 g          294 t
ORIGIN      
        1 gtttcaaagt tagtagagaa aatgtagtta tatatttaaa tttttaccag aaagaaatga
       61 acaccttcaa ttatctaaat ctcgaaaatg gttagatgta atcatcagga aaaacaatct
      121 taaacgaatt actattcatg gtcttagaca cacacatgct agcttgcttt tagcaagcta
      181 gtgcaaatat taaagatgtg caagagcgtt taggccactc ttctattcaa atcattatgg
      241 atctatatat tcatattaca gacaaaagaa aagaagaaac cgtagcgcaa ttcgcaaaat
      301 ataggctcta taatttatgg gactgatgaa tcaaaattga ttcttcagtc ccattgttat
      361 tttaggtata tgattcgtac attgaaagag ttgaaaaact atcttccgaa gccgtcaaaa
      421 aggaccctgc caaaagtatt gatggtggat gaatttcgtt cgcacgcttc aattgtggat
      481 aaaatgagct ttatttgtgc ggatggcgag actggaaaac tcattgatat tttgcctaca
      541 cgaaaattgt ctcgattaac acactatttt agtcgctgtg caaatcctga agcggtggaa
      601 tatttagtga cagatatgaa cgccgcctac ttccaactga caaaacgtgt cttaccaaat
      661 gcgaaagtcg tcattgattg ttttcatatc atcaaacatt tgaatcaggc gttcaatgat
      721 tttcgtgtac aagaaatgaa aagattacac cagttagggc aacgacggga agccgagaaa
      781 gtgaaaaaga actggcgctt tcttctaaaa aaccgtcaaa aaatcaatca ctatgattac
      841 aaaacatggc gcagttttcg tgcacctaaa tacccgctac tcactgaagc aatgatgatt
      901 gatcgattgc tggcattttc aacgccttta aaggacgcct atactttttt ccatgagctg
      961 accgaagcct ttagagacaa ggaatcagac ttatttttta c
//
LOCUS       DADQDV010000211         1000 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.222, whole genome shotgun sequence.
ACCESSION   DADQDV010000211 DADQDV010000000
VERSION     DADQDV010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1000
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.222"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(82..636)
                     /locus_tag="J8S10_003150"
     CDS             complement(82..636)
                     /locus_tag="J8S10_003150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAZ9631662.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADVAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGG"
BASE COUNT          324 a          186 c          107 g          383 t
ORIGIN      
        1 acttccgaaa attcagttat cttcattaat ctcaccttct aagttttcat tatacacaaa
       61 aaatatatcc taatatctca attagcctcc caatttaaaa ccacgtaacg atgcccctat
      121 ttcatcttca gttataccaa tgtacctttt tgtaattgct tgcgagctat gattaaaaat
      181 aaacattaag gtagcaatgt ctctagtttt cttgtagtag tgatacccaa aagtttttct
      241 taatgtatgt gttcctatat catctcttcc taatttttct gctacatctg catatatctg
      301 atagacacga tcccttgtta tatgtcgacc ttgttgccga cttggaaata accaatcatt
      361 ttcttcttta ccttcagtat ataataaaat ctcttctctc aaattatcta taaaaatcgg
      421 ttttcgctta cctgttttat gttcaacaat aataggctta cttttacctc gtatgtctcc
      481 aacttttaat cctataatat ctgacatacg taacccatta ttgattccaa acaaaaataa
      541 aaaactatct ctttctggat tacttgttct tcttagccaa aactgaaaat cttgtatctc
      601 ttcatttgtc cttaacggtt gtacattata gctcactatt gtttcccttc ttaaaaatat
      661 tctgagttca tgattatata tatattttac cataatcatg aacttatata tatactctgt
      721 taaaagtgaa gaaaatcaag gggtttagtt tatgatttta tatcatttca gtaactcaga
      781 atattccgac ttttttgtac aaaaaaatta accttactta tatgaagatt ctaagctctt
      841 atttaaattt tagacgggca gttatccgta gaagttctta gaatagctaa tttacataat
      901 taaattatat gaaatttaag tttgaacaat atactaagaa ctccccttac tataaagtga
      961 aataaattag catatgaata accgtgctac caaacttttc
//
LOCUS       DADQDV010000212          991 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.223, whole genome shotgun sequence.
ACCESSION   DADQDV010000212 DADQDV010000000
VERSION     DADQDV010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 991)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 991)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..991
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.223"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(21..94)
                     /locus_tag="J8S10_003151"
     tRNA            complement(21..94)
                     /locus_tag="J8S10_003151"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(58..60),aa:Ile,seq:cat)
     gene            complement(108..181)
                     /locus_tag="J8S10_003152"
     tRNA            complement(108..181)
                     /locus_tag="J8S10_003152"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(145..147),aa:Met,seq:cat)
     gene            complement(209..281)
                     /locus_tag="J8S10_003153"
     tRNA            complement(209..281)
                     /locus_tag="J8S10_003153"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(246..248),aa:Ala,seq:tgc)
     gene            complement(301..374)
                     /locus_tag="J8S10_003154"
     tRNA            complement(301..374)
                     /locus_tag="J8S10_003154"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(338..340),aa:Pro,seq:tgg)
     gene            complement(384..457)
                     /locus_tag="J8S10_003155"
     tRNA            complement(384..457)
                     /locus_tag="J8S10_003155"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(421..423),aa:Arg,seq:acg)
     gene            complement(468..553)
                     /locus_tag="J8S10_003156"
     tRNA            complement(468..553)
                     /locus_tag="J8S10_003156"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(517..519),aa:Leu,seq:taa)
     gene            complement(570..641)
                     /locus_tag="J8S10_003157"
     tRNA            complement(570..641)
                     /locus_tag="J8S10_003157"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(607..609),aa:Gly,seq:gcc)
     gene            complement(653..725)
                     /locus_tag="J8S10_003158"
     tRNA            complement(653..725)
                     /locus_tag="J8S10_003158"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(690..692),aa:Thr,seq:tgt)
     gene            complement(743..824)
                     /locus_tag="J8S10_003159"
     tRNA            complement(743..824)
                     /locus_tag="J8S10_003159"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(788..790),aa:Leu,seq:tag)
     gene            complement(832..904)
                     /locus_tag="J8S10_003160"
     tRNA            complement(832..904)
                     /locus_tag="J8S10_003160"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(869..871),aa:Lys,seq:ttt)
     gene            complement(908..980)
                     /locus_tag="J8S10_003161"
     tRNA            complement(908..980)
                     /locus_tag="J8S10_003161"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(945..947),aa:Val,seq:tac)
BASE COUNT          260 a          283 c          235 g          213 t
ORIGIN      
        1 tgaaacttac aacgccacaa tggaccttgt aggactcgaa cctacgaccg gacggttatg
       61 agccgtctgc tctaaccaac tgagctaaag gtccaggctc ttaaaaatcg cggcggaggg
      121 gatcgaaccc ccgacctccc gggtatgaac cggacgctct agccagctga gctacaccgc
      181 gaaaaagata ttcattattt aaatgaaatg gagcctagcg ggatcgaacc gctgacctcc
      241 tgcgtgcaaa gcaggcgctc tcccagctga gctaaggccc cgtgtttaaa tttataatta
      301 tcgggaagac aggattcgaa cctgcgaccc cttggtccca aaccaagtgc tctaccaagc
      361 tgagctactt cccgtttaat taacgcgccc aagaggagtc gaacccctaa ccttttgatc
      421 cgtagtcaaa cactctatcc agttgagcta tgggcgcata tttgaaatgc cgaggaccgg
      481 aatcgaaccg gtacggtgat cactcaccgc aggattttaa gtcctgtgcg tctgccagtt
      541 ccgccacccc ggcgcgattg ctttggcaaa gcggaaaacg gggttcgaac ccgcgacccc
      601 caccttggca aggtggtgct ctaccactga gctatttccg cgtgtttaaa gatgccggct
      661 aaaggacttg aaccctcgac cctctgatta caaatcagat gctctaccaa ctgagctaag
      721 ccggcatgta aaacttaaat tatgcgggtg aagggacttg aacccccacg ccgtaaggcg
      781 ctagatccta aatctagtgc gtctgccaat tccgccacac ccgcaaaaat atgagccgta
      841 cagggctcga acctgtgacc ctctgattaa aagtcagatg ctctaccaac tgagctaacg
      901 gctcatatgg aggttaacgg gatcgaaccg ctgaccctct gcttgtaagg cagatgctct
      961 cccagctgag ctaaacctcc atggataact t
//
LOCUS       DADQDV010000213          982 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.224, whole genome shotgun sequence.
ACCESSION   DADQDV010000213 DADQDV010000000
VERSION     DADQDV010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 982)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 982)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..982
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.224"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            82..>982
                     /locus_tag="J8S10_003162"
     CDS             82..>982
                     /locus_tag="J8S10_003162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HAZ9631663.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEY"
BASE COUNT          335 a          183 c          192 g          272 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata ca
//
LOCUS       DADQDV010000214          981 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.225, whole genome shotgun sequence.
ACCESSION   DADQDV010000214 DADQDV010000000
VERSION     DADQDV010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 981)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 981)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..981
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.225"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            39..590
                     /locus_tag="J8S10_003163"
     CDS             39..590
                     /locus_tag="J8S10_003163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF334 domain-containing protein"
                     /protein_id="HAZ9631664.1"
                     /translation="MKRLEASTSNFNNKLDVFEEKTKHARLNFETTAKHYIKRLDEDN
                     LKLDFQQAIQDELSDTKDEIREVTKQAREETKEYKEILESKIKDHNKVVDKSNTALKV
                     MTKGVTNIFFVLIIFVLVMLVTGPIGHFFGIEHLYSFINGFIDDHESAWRYLMLILYA
                     VPYVFFAIILWLIALFFRVFNDL"
BASE COUNT          375 a          136 c          188 g          282 t
ORIGIN      
        1 agagcgagca agacaggaac gagagaacaa acatactcat gaaaagacta gaggcttcga
       61 cctcgaactt taataataag ttagatgttt ttgaagaaaa gactaagcat gcaagattaa
      121 actttgaaac aactgcaaag cactatatta aacgacttga tgaagataat ttgaaattag
      181 attttcaaca agctattcaa gatgaattaa gcgatactaa agacgaaata cgtgaagtga
      241 cgaaacaagc gagagaagaa acaaaagagt ataaagaaat cttagaaagt aaaataaaag
      301 accataacaa agtggttgat aaatcgaata cagcgctaaa agtgatgaca aaaggcgtta
      361 caaatatatt ttttgtgcta attatttttg tacttgtaat gcttgtgaca ggtccgatag
      421 gtcatttctt tggtattgaa catttatata gctttattaa tggttttatt gatgaccacg
      481 aaagtgcatg gcgatatttg atgttgatac tttatgcagt accctatgta ttcttcgcta
      541 tcattctgtg gctcatagca ttgtttttta gagtatttaa tgacctttag gtagatttat
      601 atataaaaag ggctaaatac gcaaaatacc cccttaaaat gcaaaataaa tgcaaataag
      661 ggggtaactc cttatgaaaa aacaactaat agtattataa cacgttttta tgccgagaaa
      721 acttattggt tggaatgggc tatgtgttag ctaacttgtt agcgagttgg ttggacttga
      781 attgggatta atcccaagaa agtaccaact caacaacaca taaagccctg taggttccga
      841 ccaataagga aattggaata aagcaacgaa aggagttgag taaaatgagt gagaaaacga
      901 agaaaatcat tcgagtatca ttagcttttt cacaagtagt agtgcaatca ttgatagttt
      961 attatactta ccagcaatat a
//
LOCUS       DADQDV010000215          977 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.226, whole genome shotgun sequence.
ACCESSION   DADQDV010000215 DADQDV010000000
VERSION     DADQDV010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 977)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 977)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..977
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.226"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..282)
                     /locus_tag="J8S10_003164"
     CDS             complement(<1..282)
                     /locus_tag="J8S10_003164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631665.1"
                     /translation="METTDTLLQLLQEAHKTNQAQQQTIQNLTTEIQLLNEKVNYLTN
                     KLFGRSKETLFEETNGQLNLFSDEEISVSVPEAAATIIPVKGHQRVVGTK"
     gene            complement(384..737)
                     /gene="tnpB"
                     /locus_tag="J8S10_003165"
     CDS             complement(384..737)
                     /gene="tnpB"
                     /locus_tag="J8S10_003165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HAZ9631666.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            complement(727..921)
                     /locus_tag="J8S10_003166"
     CDS             complement(727..921)
                     /locus_tag="J8S10_003166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631667.1"
                     /translation="MYKLNEIVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIY
                     NGINNYILQAILKELLSNAL"
BASE COUNT          280 a          198 c          169 g          330 t
ORIGIN      
        1 tttcgttcct acaactcgtt gatgtccttt tactggaata atggtggcag ctgcttctgg
       61 aacacttaca gaaatttctt catcactaaa aagattcaat tgcccattcg tttcctcaaa
      121 gagagtctct ttagagcgtc caaataattt gttggttaaa taattgacct tttcattcaa
      181 tagttggatt tcagttgtaa gattctgaat ggtttgttgt tgtgcttgat tggttttatg
      241 ggcttcttga agcaactgaa gcaacgtatc tgtagtttcc aaaatttttc accaccttga
      301 atcgaactga ttttgttaca gaataccaca agaaacgcac aagaaatagg ggttcaacac
      361 attttttgtg ttaacccccc agcttaaaaa actccttttt ttcctggcaa aatagctcga
      421 ggttgatcga tacttaatcc ttctaacaac catcgaacct gttggttcgt taaggttcga
      481 acttcgtctt tcgtccgagg ccattttaac ttgccgtttt ctatccgctt ataacagaga
      541 agaaaaccat caccgtccca atagagaagt ttgaaacggt cttgacggtt cccgcaaaat
      601 aaaaaaacgg catcttcgta aagctcgagt tgatactctt gttgaataag actggcaaga
      661 ccatcaattc cttttcgcaa atctgttttt ccgcacacaa tataaatatg tttggtttga
      721 agtaaatcat aaagcattgg acaacagttc tttcaaaata gcttgaagaa tataattgtt
      781 aataccgtta tagatcaaaa cttcagaacc attctctctt ttgatgcgca tcgctaactt
      841 ggcagccgcg ggtttacctt tttctggtgc actcttttcg tttcctaatt ggacaggaac
      901 aatctcattt aatttataca tagaaaacct ccagacttct tgatagctca agtatatctt
      961 gaggtgcatt tgttagt
//
LOCUS       DADQDV010000216          944 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.227, whole genome shotgun sequence.
ACCESSION   DADQDV010000216 DADQDV010000000
VERSION     DADQDV010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 944)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 944)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..944
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.227"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..900
                     /locus_tag="J8S10_003167"
     CDS             <1..900
                     /locus_tag="J8S10_003167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAZ9631668.1"
                     /translation="LKFLPYSLLISILFSAIISLIYAKSIKNNIQEIKIVTDKMMKLD
                     KKMSLKVSSNDEVGELKQQINDLYSTLLRTIDDLEFKNKEILKLEKLKYDFFKGASHE
                     LKTPLASLKIILENMKYNIGKYKERDIYINECIEIVDSLTKNISQILSVHSIENLNND
                     EEYLKINDTLEDILKKYEILANQKKITVNNYILDENVYIGKTALKIILSNLISNAVKY
                     TDVNGVINIGIVNDWLYIENSYGNNKISNMDKIFDVKFDLNKENSNGLGLYIVSNILN
                     NYNIEYKVLQDEEFFIFKIKIFS"
BASE COUNT          417 a           68 c          123 g          336 t
ORIGIN      
        1 cttaaatttt taccatattc tttattaata tcaattttat tttctgctat tatttcttta
       61 atttatgcaa aatcaataaa aaataatata caagaaataa aaattgttac tgataaaatg
      121 atgaaacttg ataaaaaaat gagtttaaaa gttagctcta atgatgaagt tggagaatta
      181 aaacaacaaa ttaatgattt gtattctact ttattaagaa caattgacga tttggaattt
      241 aaaaataaag aaattttaaa attagaaaag ttaaaatatg acttttttaa aggtgcatcc
      301 catgaactta aaacccctct tgctagtctt aaaataatac tggaaaacat gaaatacaat
      361 attggaaaat ataaagaaag agatatttat attaatgaat gtattgaaat cgttgatagt
      421 ttaacaaaaa atatttctca aatattatca gttcattcta tagaaaattt gaataatgat
      481 gaagaatatt tgaaaataaa tgatacatta gaagacatat taaaaaagta tgaaatatta
      541 gcaaatcaaa agaaaataac tgtcaataat tatatattag acgagaatgt ttatatagga
      601 aaaacagctt taaagattat tctatctaat ttgattagta atgcggtaaa atatactgat
      661 gtaaatgggg taattaatat tgggatagtt aatgattggt tatatataga gaattcatac
      721 ggtaacaata aaatttcgaa tatggataaa atatttgatg ttaaatttga tttaaataag
      781 gaaaatagta atggattagg tttatatatt gtaagtaata ttctgaataa ttacaatata
      841 gaatataaag tattgcagga tgaagaattt tttatcttta aaataaaaat attttcttaa
      901 ttaagatata attttgcaat agttattgaa aaatagagac ttat
//
LOCUS       DADQDV010000217          906 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.228, whole genome shotgun sequence.
ACCESSION   DADQDV010000217 DADQDV010000000
VERSION     DADQDV010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..906
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.228"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..720
                     /locus_tag="J8S10_003168"
     CDS             <1..720
                     /locus_tag="J8S10_003168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HAZ9631669.1"
                     /translation="GKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFT
                     NRLGTNKRGRLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVY
                     LANCYTLEGRKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITL
                     EEFQQANEIHCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNK
                     VQLIRLNKYRVLAGNQELNLI"
BASE COUNT          339 a          143 c          178 g          246 t
ORIGIN      
        1 gggaaaacgg aattagaaga aacaagactt tataattcaa tggtattagg tatgcaaaat
       61 tattatcaga ttgcaacgaa tgtaaatctg gattgtatga aactgaatag agctgtaatg
      121 gctatcttca ctaacagatt aggtacaaac aaaaggggca gattgagaaa aacaggcaga
      181 caacttacga caaaggaggc aacaagatat ggtaaatcta aaatgcttcg gtatgttgct
      241 ggcgagggcg aacctatttt ccctgttgga tatatccaac acagaaaacc aatggcaaag
      301 gtgtatttag cgaattgcta cactctagag ggaagaaaat ttatccacac caatctaagt
      361 gttgataaat tactgatgta ccagttaatg aaattatctt tggaaaatcg cacaatagaa
      421 tacgcagaca atcgaatttc gctattttct gctcaacatg gaaaatgtgc tataactctg
      481 gaagaatttc aacaagctaa tgaaatacat tgtcatcata ttgtaccaac tggagctggt
      541 ggaaatgacg attataaaaa tcttattttg gtaaaagagg cggtacaccg tctaatacac
      601 gctaaaacag aagaaacaat acaaaaatat atagctctat tgaagctaaa taaagtccag
      661 ctcataagac taaataaata tagagtatta gctggcaatc aagaattaaa cttgatatag
      721 gtctactaca taaatacttt tcaatataaa cacgatggaa cgcggagtgc ggtgaaagtc
      781 gcacgctccg tgtgaatggg gggaaaagtt tgagatattt ataatatcag gaacttacct
      841 atccatatat caatggtttt taaccaatgc tcaatcttta gtcttactag cgattgtggt
      901 cattgg
//
LOCUS       DADQDV010000218          902 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.229, whole genome shotgun sequence.
ACCESSION   DADQDV010000218 DADQDV010000000
VERSION     DADQDV010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 902)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 902)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..902
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.229"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
BASE COUNT          348 a          103 c          114 g          337 t
ORIGIN      
        1 attagcaata tataaaagaa ggtatcaaga gtcacagtga atttattccg aaaagtgaaa
       61 agagcaaata taaaatttaa taaaaataag aactaaatag gaaaacgtag acgtaatttt
      121 ctacgttttc cttttcatat atattaaata ttacggaaaa ttatataaac taatttagtg
      181 ttttgtttgt aattcctaat tttgctccac ttttagataa tttttaggtc tatttaactc
      241 attagacatt ctatgctcat ttttctccaa atttgtttca actctttcgt acttaatttt
      301 gcgtatttga aaattcttct tttagagtac ttttattacg atactagtat gatatatatc
      361 tacagcaaac agttaaaatc ttcctaaaat aagcgaatag cattcctaaa acctataaaa
      421 tttttagatg aagcgacaag tggacaatta ataaactact tgaacatgaa attatggatc
      481 acctttcaaa tttagaaaat ggaattctta tacttattgc gcaacattta ttgattgcaa
      541 aattatgtga caaaaagaac tagtagaaga aggaataatg gcttgataat aaagtactac
      601 ctattaaagg tagtacttta tttaatttag tataaattaa catactacta tattttaggt
      661 ttcatattat ataaattaat aatatactac catttgttgg tagtataatt taaaggtaat
      721 aagttattct tttattacta tgtttgggtt ttatagcaaa gaaagtttaa taagagtttg
      781 gacctagcaa acaatattaa tgaggtcatt aaatcttatt atctttagtg atataatgaa
      841 atatctacac ggacaaaatt atgatcttgc gtaaagttat aaaatattaa taaaaatatt
      901 tt
//
LOCUS       DADQDV010000219          890 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.231, whole genome shotgun sequence.
ACCESSION   DADQDV010000219 DADQDV010000000
VERSION     DADQDV010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 890)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 890)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..890
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.231"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..888
                     /locus_tag="J8S10_003169"
     CDS             <1..888
                     /locus_tag="J8S10_003169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HAZ9631670.1"
                     /translation="RNLDSRTRFEQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYY
                     WVKKLDKPDKYSKIKQEITAIVKESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMG
                     LTCQIRIKRYKSYKGTVGKIAKNVLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPIL
                     DLFNGEIISYSISTSPTYKLIEEMLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLK
                     ENNIIQSMSRKGNCLDNSVIENFFGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKR
                     IKLKLNGLSPVEYRKQSIK"
BASE COUNT          386 a          116 c          144 g          244 t
ORIGIN      
        1 agaaaccttg attcaagaac aagatttgag caagaagaaa tcaaggttaa aacaatcctt
       61 cagctcaaaa aagaatttaa attgaatcta ttactttcaa ttgcacaatt agcgaagtca
      121 acttattatt actgggtaaa aaaattagat aagccagata aatatagcaa gataaagcaa
      181 gaaattacag cgattgtaaa agaatcaaga aactcttatg gttatcgtag agtcacttta
      241 gcgttaaaga tgaaaggata tacaatcaat cataaaacag ttagaaaatt aatgtcccaa
      301 atgggactta cctgtcaaat ccgaataaag cgatataaat cttataaagg aacagtagga
      361 aaaattgcca agaatgtgtt aaaacgaaat ttttcagtag atacacccaa taaaaaatgg
      421 gtgacagacg tcactgaatt caagataaaa ggaagaaaaa tctatctatc tcctatactt
      481 gatttattta acggagaaat aattagttat agtatatcaa ctagtccaac atataaactg
      541 attgaagaaa tgcttcaaca agcaattaaa aaaaagggaa ctgagggttc actgattcta
      601 cattcagatc aaggatggca gtatcagatg ccacaatatc aaaaaaaatt aaaagagaat
      661 aacattattc aaagcatgtc tagaaaagga aattgcttag ataattctgt aatagaaaat
      721 ttttttggtg tgcttaaatc agagtttttt tatcgagaaa aattccgatc aattgagata
      781 tttcaaagta aattaaatga gtatattagg tggtataata acaaaaggat aaaactaaag
      841 ttaaatggac tatctccagt agaatatcgg aaacagtcca ttaaatagtt
//
LOCUS       DADQDV010000220          872 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.232, whole genome shotgun sequence.
ACCESSION   DADQDV010000220 DADQDV010000000
VERSION     DADQDV010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 872)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 872)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..872
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.232"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            1..368
                     /locus_tag="J8S10_003170"
                     /pseudo
     CDS             1..368
                     /locus_tag="J8S10_003170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012655884.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside phosphotransferase family
                     protein"
     gene            352..744
                     /locus_tag="J8S10_003171"
     CDS             352..744
                     /locus_tag="J8S10_003171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAZ9631671.1"
                     /translation="MKLLFIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCY
                     TLLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRA
                     CHVYEKLGGKNDYKDEIVYVYDYEKGDK"
BASE COUNT          349 a           57 c          155 g          311 t
ORIGIN      
        1 tattgttgcg tgaaactatt tataatgatt taactgatat agaaaaagat tatatagaaa
       61 gttttatgga aagactaaat gcaacaacag tttttgaggg taaaaagtgt ttatgccata
      121 atgattttag ttgtaatcat ctattgttag atggcaataa tagattaact ggaataattg
      181 attttggaga ttctggaatt atagatgaat attgtgattt tatatactta cttgaagata
      241 gtgaagaaga aataggaaca aattttggag aagatatatt aagaatgtat ggaaatatag
      301 atattgagaa agcaaaagaa tatcaagata tagttgaaga atattatcct attgaaacta
      361 ttgtttattg atgataatat ggtttttgat attgataatt taaaaggatt tcttaatgat
      421 accagttcat ttgggtttat agctaaagaa aataataaaa ttataggatt tgcatattgc
      481 tatacacttt taagacctga tggaaaaaca atgttttatt tacactcaat aggaatgtta
      541 cctaactatc aagacaaagg ttatggttca aaattattat cttttattaa ggaatattct
      601 aaagagattg gttgttctga aatgttttta ataactgata aaggtaatcc tagagcttgc
      661 catgtatatg aaaaattagg tggtaaaaat gattataaag atgaaatagt atatgtatat
      721 gattatgaaa aaggtgataa ataaatgaat atagttgaaa atgaaatatg tataagaact
      781 ttaatagatg atgattttcc tttgatgtta aaatggttaa ctgatgaaag agtattagaa
      841 ttttatgatg gtagagataa aaaatataca tt
//
LOCUS       DADQDV010000221          814 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.233, whole genome shotgun sequence.
ACCESSION   DADQDV010000221 DADQDV010000000
VERSION     DADQDV010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 814)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 814)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..814
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.233"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(25..630)
                     /locus_tag="J8S10_003172"
     CDS             complement(25..630)
                     /locus_tag="J8S10_003172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAZ9631672.1"
                     /translation="MGKIGYIRVSSQDQNLDRQLAMMEGLNIDKLFQEKASGKDTERP
                     EFQKLLNYIREGDCVIVTSLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGN
                     ELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAQKAGRYKGRPIEYSINSTDPQ
                     KRLVFKTVVDMLKQGIPVAEIAKENGISRPTIYKIKKANDL"
BASE COUNT          251 a          144 c          122 g          297 t
ORIGIN      
        1 aaagcgaatg aatgtagtat atttctacaa atcattcgct ttctttattt tataaatagt
       61 tggtcgagag atcccgtttt cttttgcaat ctctgcaact ggaatgcctt gctttaacat
      121 gtccaccacg gttttaaaaa ctaagcgttt ttgcggatct gttgagttaa tagaatactc
      181 gattggtcgt cccttatatc ggccggcttt ttgagccaat aatactcctt gccgctgacg
      241 ttcacgaatt ttctcacgct cgttttgtgc aatataactt agcagtgata aaaacatatc
      301 gaacatagcg gtatccagga gttcatttcc agtattaaaa tctaaaaact gtgcatctaa
      361 tatttttaac gctacttttt tctgtttcat aaaagcaact gtatttttta tatcttcata
      421 atctcttcct aaacgatcta gtgatgtaac gatgacgcaa tcaccttcac ggatataatt
      481 tagtaatttt tgaaactcag gacgctcagt atctttacca ctggcttttt cttggaataa
      541 tttatcaatg ttaagtcctt ccatcattgc caattgtcga tccaaatttt gatcttgtga
      601 agatactcga atatagccaa tttttcccat aaaaaactcc tttttaaaag tgatataatt
      661 tacatgtaaa atttacttgt agttttactg ctatcatagc atttttaaaa ataaatttta
      721 tgtagactta aaatttactt catggagggt ttaaatggat gaaatcaaaa gtaacaaaaa
      781 agcatttggc atttatttag gagaacctag taca
//
LOCUS       DADQDV010000222          800 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.234, whole genome shotgun sequence.
ACCESSION   DADQDV010000222 DADQDV010000000
VERSION     DADQDV010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 800)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 800)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..800
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.234"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(324..524)
                     /locus_tag="J8S10_003173"
     CDS             complement(324..524)
                     /locus_tag="J8S10_003173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAZ9631673.1"
                     /translation="MKINYTVDLVSFSLVINFSLFSLRLFIDGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMSTYTK"
BASE COUNT          287 a          125 c          127 g          261 t
ORIGIN      
        1 tctttttcgt tgctttgctc ataaaaatct gcatattcat cactaatatt ttttctaata
       61 aattcttcca tcataaagat cacctcgaaa agagtatacg aacaaacgtt ctttttgtaa
      121 aggtggaatt tattatacta aataaatagg tgaacaagta cttgtgccaa attatgtgcc
      181 aaaaaaaatc gaatttaata aaacacaaac aaaaagaaat cctattatga taacatttct
      241 tataataaca aacacaacag aagacgtgta atagttagtc aggaacgtac aaataacccc
      301 tgtatccttt gcggtacagg gggttatttt gtataagtag acattgtagt ttctaaactg
      361 ctatgtccta aacgtttcga tacgctaagt atatttactc cttgataaag taaaatagat
      421 gcatgcgtat gtcttagtcc atcaataaac agtcgaagag aaaataggga aaaattgatt
      481 actaaagaaa aacttactag gtcgacggtg tagttgattt tcatacttca atagattcga
      541 attaaacgat ttcgattggc ttataccagt cctatccaac gaaagatata tcgttcttaa
      601 ctctagcggt ataacttgaa gctttacgta aagccaatgg gaatgaactg gagatgactt
      661 tttattattt ttagtaatag ctgatgggtt aatacttaca actttccttt tcaaagtacc
      721 atataaaaaa acggtggggt tgtttagcga aataaaggat ctaagccaat agcttagatc
      781 ctttattcta tgctttatat
//
LOCUS       DADQDV010000223          791 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.235, whole genome shotgun sequence.
ACCESSION   DADQDV010000223 DADQDV010000000
VERSION     DADQDV010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..791
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.235"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            24..716
                     /locus_tag="J8S10_003174"
     CDS             24..716
                     /locus_tag="J8S10_003174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HAZ9631674.1"
                     /translation="MGLAFLLAGCTNGNESKKESTKETAKATVATTTTTSTESKSTAA
                     STETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNADKSAQLEAF
                     MTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEWSESGTGQA
                     DYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFNETANNELK
                     NGFNQIVYGQAN"
BASE COUNT          282 a          151 c          159 g          199 t
ORIGIN      
        1 tgaaaaaaag gattttagta acaattggtc tagctttttt gttagctggt tgtaccaacg
       61 ggaatgaatc gaaaaaagaa tcaacaaaag aaacagcgaa agcaacagtt gcaactacta
      121 caacaactag cacagagagc aagtcaactg cagcaagtac agaaacagca gatacctcta
      181 cttcgtcaga gtcttccaaa acgactgaaa caactcaaac atctacttca agttcttctg
      241 tagaggcttc atcttcctct tcagaaagca gcgaacaagt tgaacaaaca ctgtggaatg
      301 cagacaaatc cgcacaatta gaggcattta tgaccaaatg gggccaaaca atgggacaac
      361 aatacaaaag ttatacgaat caaatgagtg tggacttata tggtcttaaa gtccctcaag
      421 ctattttgaa cggggagtgg aagatggcta ttggtggagt gcctgtttct gcagaatggt
      481 cagaaagtgg gacaggtcaa gcagactatc aaatcacagc cgtctattcc gatgcagaga
      541 cagaaccata tctgaaaaag cacgtctatc tattcgggtt tcagcaaaat cagccaaaag
      601 tattggtgac acaacaaaat caggggaatc ccgataatta tctttacttc aacgagacag
      661 cgaataatga attgaaaaat ggctttaatc aaatcgttta tggacaagca aattaatgag
      721 ataaacaagg ggttgtgaca tgtcttttat cacaacccct tgctcagttt atttgttagt
      781 cttttatttt t
//
LOCUS       DADQDV010000224          759 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.236, whole genome shotgun sequence.
ACCESSION   DADQDV010000224 DADQDV010000000
VERSION     DADQDV010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 759)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 759)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..759
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.236"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            71..154
                     /locus_tag="J8S10_003175"
     CDS             71..154
                     /locus_tag="J8S10_003175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HAZ9631675.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            279..>759
                     /locus_tag="J8S10_003176"
     CDS             279..>759
                     /locus_tag="J8S10_003176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004292767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAZ9631676.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     "
BASE COUNT          290 a          119 c          121 g          229 t
ORIGIN      
        1 ttttgtgtat aataggaatt gaagttaaat tagatgctaa aaatttgtaa ttaagaagga
       61 gggattcgtc atgttggtat tccaaatgcg taatgtagat aaaacatcta ctgttttgaa
      121 acagactaaa aacagtgatt acgcagataa ataaatacgt tagattaatt cctaccagtg
      181 actaatctta tgacttttta aacagataac taaaattaca aacaaatcgt ttaacttctg
      241 tatttattta cagatgtaat aacttcagga gtgattacat gaacaaaaat ataaaatatt
      301 ctcaaaactt tttaacgagt gaaaaagtac tcaaccaaat aataaaacaa ttgaatttaa
      361 aagaaaccga taccgtttac gaaattggaa caggtaaagg gcatttaacg acgaaactgg
      421 ctaaaataag taaacaggta acgtctattg aattagacag tcatctattc aacttatcgt
      481 cagaaaaatt aaaactgaac attcgtgtca ctttaattca ccaagatatt ctacagtttc
      541 aattccctaa caaacagagg tataaaattg ttgggagtat tccttaccat ttaagcacac
      601 aaattattaa aaaagtggtt tttgaaagcc atgcgtctga catctatctg attgttgaag
      661 aaggattcta caagcgtacc ttggatattc accgaacact agggttgctc ttgcacactc
      721 aagtctcgat tcagcaattg cttaagctgc cagcggaat
//
LOCUS       DADQDV010000225          744 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.237, whole genome shotgun sequence.
ACCESSION   DADQDV010000225 DADQDV010000000
VERSION     DADQDV010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 744)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 744)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..744
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.237"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            178..381
                     /locus_tag="J8S10_003177"
     CDS             178..381
                     /locus_tag="J8S10_003177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HAZ9631677.1"
                     /translation="MKHCVILGILGTCLAGIGTGIDVDAATYYGNGLYCNKEKCWVNW
                     GQSWSEGLKRWGDNLFGSFSGGR"
     gene            381..731
                     /locus_tag="J8S10_003178"
     CDS             381..731
                     /locus_tag="J8S10_003178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HAZ9631678.1"
                     /translation="MTSINIDHTKKVIHELYNSLMTRPNQTKALLDITDVLFQVYKKI
                     DTAKYPEILVNKLVNYIYIVGFDNKIRFIDNDEKLLIELGDISKKAGINSKYKANFTD
                     KSQFYSYSETMPQR"
BASE COUNT          300 a           80 c          120 g          244 t
ORIGIN      
        1 gacttccttt tttgtatgga ttttttcatt tacacaaaat attttacact ctcgtcaatc
       61 attgttatat aataaaatgt tatataataa aattactaat gatatttaat attacaagca
      121 atcttaagaa attcgaaaag gaaaaaatga ttatgaaaaa gaaagaaaaa gaaagtattg
      181 aaacattgtg ttattctagg aatattagga acttgtctag ctggcattgg tacaggaata
      241 gacgttgacg cagctactta ctatggaaat ggtctttatt gtaacaaaga aaaatgttgg
      301 gtaaattggg gacaatcatg gtcagaaggg ttaaaacgtt ggggagataa tctttttggt
      361 agttttagtg gaggacgata atgacttcaa taaacattga tcacacaaaa aaagtcatac
      421 atgaattata caatagttta atgacacgac ctaatcagac gaaagcatta ttagatatta
      481 ctgatgtttt atttcaggta tataaaaaaa ttgatacagc aaaatatcct gaaattcttg
      541 taaataaatt agttaattat atttacatcg tgggttttga taataaaata cgctttattg
      601 ataatgatga aaaattatta atagaattag gggatatttc taaaaaagct ggaattaata
      661 gtaaatacaa agcaaacttt acagataaat cgcaatttta tagttattca gaaacaatgc
      721 ctcaacgata aaatatagta tact
//
LOCUS       DADQDV010000226          727 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.238, whole genome shotgun sequence.
ACCESSION   DADQDV010000226 DADQDV010000000
VERSION     DADQDV010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 727)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 727)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..727
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.238"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            24..503
                     /locus_tag="J8S10_003179"
     CDS             24..503
                     /locus_tag="J8S10_003179"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631679.1"
                     /translation="MSRKIDNIILLTTIFYLVIGATLSLLSFLSNSSLIVLNQKSILT
                     EFAHIDYFSFFKTGLICLFLSSFILYIGTTFCLMVLNLKMFIIEKWIVIIAKIFSSIS
                     IIIPMTLTFSKEQFNVATTFVSFIALFSFAVPKTFQSKSSNAKVNVENTDRKNDESY"
BASE COUNT          239 a          123 c          101 g          264 t
ORIGIN      
        1 tataattctg gtggggtgaa aacatgagca gaaaaattga taatataata ttgttaacaa
       61 ctatttttta tttagtaatc ggagcaactc tttccttact gtcatttttg tccaacagta
      121 gtttgattgt gttaaatcaa aaaagcatat taacagaatt tgcccacata gattacttct
      181 ctttttttaa aactggacta atatgtttat ttctatcttc atttatcctc tatataggaa
      241 ctacattttg tctaatggtg cttaatttaa aaatgtttat aattgaaaaa tggatagtta
      301 ttatcgcaaa gattttctca tcgatatcaa ttatcattcc aatgacattg acgttttcta
      361 aagagcaatt taacgtagct actacattcg tatcttttat agctctattt tcgtttgctg
      421 ttcctaaaac ttttcaaagc aaatctagca acgcaaaggt taatgtagaa aacactgata
      481 gaaaaaatga tgaaagttat taaaaaaaat aattctttca tttattgtca aacctttctt
      541 atagacatta gactttttta gtcagtccct cccgactggc tttttcgctc tgtactcagc
      601 ttcatcaagc ccaatgaaaa tccaaagcat gtaaacgatc gtgccgatta atgcttgtct
      661 actaccccat agacctaaag cgtagataat tagtggcgcg ctgaatacta atgttcgatt
      721 aaacttt
//
LOCUS       DADQDV010000227          682 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.239, whole genome shotgun sequence.
ACCESSION   DADQDV010000227 DADQDV010000000
VERSION     DADQDV010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..682
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.239"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..652
                     /locus_tag="J8S10_003180"
     CDS             <1..652
                     /locus_tag="J8S10_003180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HAZ9631680.1"
                     /translation="QDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHTTIYRWVQEY
                     GKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWLRKKRDTQA
                     AYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLNNLIEQDH
                     RPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLLGIPA"
BASE COUNT          232 a          120 c          136 g          194 t
ORIGIN      
        1 gcaggatgtg attattgtag ccgtgggcta ctatcttcgt tataacctta gctatcgtga
       61 agttcaagaa atcttatatg atcgtggcat taacgtttct catacgacga tttatcgttg
      121 ggtgcaagaa tatggcaaac tactctatca aatttggaaa aagaaaaata aaaaatcctt
      181 ttattcatgg aaaatggatg aaacgtacat caaaattaaa ggaaaatggc attatttgta
      241 tcgagccatc gatgcagatg gtttaacctt ggatatttgg ttacgtaaaa aacgggacac
      301 acaagcagcc tatgcttttc ttaagcggtt agtgaagcag tttgatgaac cgaaggttgt
      361 agtcacagat aaagccccct ctattacaag tgcctttaag aaactaaaag aatacggctt
      421 ttatcaaggg acagaacatc gtaccattaa atacctgaat aatttgattg aacaagacca
      481 tcgtccagta aagagacgca ataaattcta tcgaagttta cgcactgcct ctaccacgat
      541 taaaggcatg gaagccattc gaggattata taagaaaacc cgaaaagaag gcactctctt
      601 cgggttttcg gtctgtactg aaatcaaggt attattggga atcccagctt aaatcataga
      661 taccgtaagg gattttattc tt
//
LOCUS       DADQDV010000228          677 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.240, whole genome shotgun sequence.
ACCESSION   DADQDV010000228 DADQDV010000000
VERSION     DADQDV010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..677
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.240"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
BASE COUNT          240 a          112 c           80 g          245 t
ORIGIN      
        1 aattacttca tcaaaacatt gatataattt ttattatatc agtatttatt cttgatacat
       61 aaatgagaaa ataaatactt taaatctatt gactacaagt agtcattaag tcttcataag
      121 atgtacaata tgacattaaa aaaataaaag cttacgacca tccgttaaat ctgacactaa
      181 ataatggact gctttctttt gtattagcag gttacgttga ctatgaatat tcaccagatt
      241 atttggagaa acctcttcaa cacgagaaca atgatattaa ttttagattt gtctacgagt
      301 caaaaagtaa aacatggtta gttgatcaat taagcacgat aaacacaagc ttccatgaat
      361 tacctaaacc tgaaaatgaa gttgagatgg tcattaaaat cttctaaaaa agaagcgttg
      421 aaggggaaat attcctttca acgctctttt ttatatgctt agaaacataa ataaattgta
      481 tactttcttt ttagccccta ttacttttca cgaaaaatat ctttttttcg acgctagcgt
      541 ttctctactt ctaatactgt acacagtttt tgtattattg aaaaattact cattatttag
      601 cattaatcca catcgtttta tcaatcgacc ttcatactaa actactttaa agtcatcttc
      661 cttctcgttt ttcatta
//
LOCUS       DADQDV010000229          649 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.241, whole genome shotgun sequence.
ACCESSION   DADQDV010000229 DADQDV010000000
VERSION     DADQDV010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 649)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 649)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..649
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.241"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>649
                     /locus_tag="J8S10_003181"
     CDS             <1..>649
                     /locus_tag="J8S10_003181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAZ9631681.1"
                     /translation="KSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPISCSA
                     RTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEFGHL
                     EGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFKSIT
                     FDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNSV"
BASE COUNT          213 a          111 c          134 g          191 t
ORIGIN      
        1 aaatcaaact gtggtagacg tccgcttgtt ttacccgagg aacaatcaga atatattcaa
       61 agaaaggttg ttcaaggatg gacacccgat gtgattgttg gtcgtgcagc gtttcctatt
      121 agttgttctg ctcgtaccat ttatcgtatg ttcaaaaagg ggctatttga ttcttctgac
      181 ttaccgatga aaggcaagcg taaaccgaat ggacatcaag aaagacgtgg aaaacaaact
      241 ttccgccgct ctattcatga acgtgaaaag gattatagcc aattctcaaa tgagtttggt
      301 caccttgaag gtgacactat cgtaggtctg aaacataaaa gtgctgtaat taccttagtt
      361 gaacgattat caaaagttat catcacattg aaaccgtgtg gtagacaagc gattgatatt
      421 gaaaaaaaat taaatcaatg gtttgaatct gtaccgaaaa acctattcaa atccatcact
      481 tttgattgtg gaaaggaatt ttcaaattgg aaacagatca gtaatgtcaa tgatattgcc
      541 atttatttcg ctgatccagg aacgccgtct caaagaggcc taaacgagaa ttctaacgga
      601 ttgttacgta gagatggttt attgaaatct atggatttca attcagtag
//
LOCUS       DADQDV010000230          582 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.242, whole genome shotgun sequence.
ACCESSION   DADQDV010000230 DADQDV010000000
VERSION     DADQDV010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 582)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 582)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..582
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.242"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>582
                     /locus_tag="J8S10_003182"
     CDS             <1..>582
                     /locus_tag="J8S10_003182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982-like element ISEfm1 family transposase"
                     /protein_id="HAZ9631682.1"
                     /translation="IKKLTKGELVGIIDSFPSPLCKPVRNRQAKLLNQIAKVGYNSTK
                     KSYFYGLKIHMIVTKTGFPITYSITNPGVHDVKVLETLSEEANLPNILGDKGYISHKI
                     HEKLALKGITISVPPRKNMDKSEKLDHSLLGKQRKTVETVFSSLEKLGCQNFNSRSVK
                     GLESRFESILLAYSVLLSRAQRRFEGTLRYSLGY"
BASE COUNT          209 a          102 c          104 g          167 t
ORIGIN      
        1 atcaagaagc tcaccaaagg tgaactagtc ggaattatag atagttttcc tagtccatta
       61 tgtaaaccag ttagaaatag acaagcaaaa ctattgaatc aaatagccaa agttggctat
      121 aactcaacaa aaaaatctta tttttatggt cttaaaattc atatgatcgt tactaagact
      181 ggctttccga ttacttactc aatcacgaat ccaggtgtcc atgacgtgaa agtgttagag
      241 actttatcgg aagaagcgaa tcttcccaat atcctagggg acaaaggata tattagccat
      301 aaaatccatg aaaagcttgc ccttaagggc attactatat ccgttccgcc acgtaaaaac
      361 atggataaat cagaaaaact agaccacagc ttacttggaa aacaaagaaa aacagttgag
      421 actgtttttt cttccttaga aaaattaggt tgtcaaaatt tcaactcacg ttctgttaaa
      481 gggctagaga gtagatttga aagcatatta ctggcttaca gtgttctatt aagtcgagca
      541 caacgacgtt ttgaaggaac tttgagatat tctttaggat at
//
LOCUS       DADQDV010000231          571 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.243, whole genome shotgun sequence.
ACCESSION   DADQDV010000231 DADQDV010000000
VERSION     DADQDV010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 571)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 571)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..571
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.243"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
BASE COUNT          186 a           81 c           81 g          223 t
ORIGIN      
        1 tcttgatgtg atatccttgt cttttttgta atgtttttaa cttattgctt ttgcaaaatt
       61 tatttacctg ttttctggat caacgatagt gtacattatg ctatccttgt ttggatttta
      121 ggacgtttaa agaggcactt ttttacataa cttaatccat agacctttta agcatgctgt
      181 gagataataa taaagaagag tttaaagcgc accccaaacc acttccccat aagtgtatta
      241 cgctttaaac tcttttatat ttgaattcac taagaagcat accatatttt tgaaaaaaag
      301 tgagaaaaaa ggcttataat taggatttag agtaattaat tagatgttta ttttatagga
      361 ctgatactat agattacaaa tagtatcgta tttcgcaatc ttaaaattat cttcttactg
      421 tgaataagat aataaaattt gtatttgtcc tttttaggta acttatttta atctatatac
      481 ctttctggat caacgaaagt atactttata tagtcataac gccgatggta actatgcact
      541 gtaacgataa tgctgctaaa atatcttttt a
//
LOCUS       DADQDV010000232          567 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.244, whole genome shotgun sequence.
ACCESSION   DADQDV010000232 DADQDV010000000
VERSION     DADQDV010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 567)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 567)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..567
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.244"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            79..>567
                     /locus_tag="J8S10_003183"
     CDS             79..>567
                     /locus_tag="J8S10_003183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HAZ9631683.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAI
                     FMD"
BASE COUNT          214 a          104 c           92 g          157 t
ORIGIN      
        1 aaaatccata caaaaaagga agtcccttct gtagaataaa gttaacgaca accaattcac
       61 agaaaagagg acttccctat gaatgatttt actacagaaa ttgtgcaaac tctagtcact
      121 aaaggcgatt taaatgaatt attccgttcg cacttagaaa aagcgataaa cacactccta
      181 cggactgaat taacggcttt tttagattac gaaaaatatg atcgcactgg ttttaattca
      241 ggtaattcga gaaacggttc ttactttcga tcaatcaaaa ccgaatatgg tgaattaaca
      301 ttggaaatac ctagagatcg taatggtgag tttaaacaac aaactttacc agcctacaaa
      361 agaacaaacg atacattgga aaccactatt atccatttat tcgaaaaagg tgttacgatg
      421 tctgaaattg ctgatttgat cgaaaaaatg tacggtcatc actatactcc acaaaccatg
      481 tccaacatga ctaaagttct gactgaagaa gtaaatgcct ttaaatccag agccttaaat
      541 gataagtatg tcgctatttt tatggac
//
LOCUS       DADQDV010000233          560 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.245, whole genome shotgun sequence.
ACCESSION   DADQDV010000233 DADQDV010000000
VERSION     DADQDV010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 560)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 560)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..560
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.245"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
BASE COUNT          187 a           88 c           87 g          198 t
ORIGIN      
        1 gaagagtatt atacaagcta aagcttttct tcattgccac tcaaatgagt ggctttttta
       61 tgtatccttt tatggattaa tgaaaggatg tttcacatag ttatacttct gtatatttga
      121 aaagttttac tttgattttt aaatagaaag acatttgggt taaattgtga gataataata
      181 aagaagagtt taaagcgcac cccaaaccac ttccccataa gtgtgttacg ctttaaactc
      241 ttttatattt gaagccatta aaaagcatac catatttttg aaaaaaagtg agaaaaaagg
      301 cttacaattg gagtggtagt taattagtga cttatttttg attttatagc actgatacta
      361 taaaatatag atatcatcat attacacaat cttaatacta acttaaaaaa tatctccttt
      421 cacaagtatg gtgataaaat tcgttccggg ctaccttttt aggtagccta ctttaatctt
      481 tatacctttc tggatcaacg aaagtatact ttatatagtc ataacgccga tgatcgctac
      541 gtgcgtccgg cacgtcagtc
//
LOCUS       DADQDV010000234          554 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.246, whole genome shotgun sequence.
ACCESSION   DADQDV010000234 DADQDV010000000
VERSION     DADQDV010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 554)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 554)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..554
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.246"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..218)
                     /locus_tag="J8S10_003184"
     CDS             complement(<1..218)
                     /locus_tag="J8S10_003184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HAZ9631684.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYYQKLTDNPIGFGLLPEDDEGNE"
BASE COUNT          160 a          128 c           75 g          191 t
ORIGIN      
        1 cattcattac cttcatcatc ttcaggtagc aagccgaatc caattggatt atcagtcaat
       61 ttttgatagt ataaatcatc ctcgtctaat gctaaaacat ctaatccttt acaatttccg
      121 cctcttctaa acgtcacaaa tcctttgtaa tcccaacgtt ggaaagaaac cttaatagta
      181 tgtgtgccca atcgtatatt cggatcataa tttttcattt gtcattcctc cattacgtaa
      241 atttcatttt ctctatgttt tatatcaatt ttttcacttt attcaggact cgttcatatt
      301 ttatcgtttt tcgtttactt aaaaatacat aaaaaatatc gactcgttta tggcgtccga
      361 aacgagaaac cctagtagaa atcggtaaat gctcgattga tccaatgacc aacgtcctcg
      421 caagtatcta catgtactgc agcacacgac acaatttctt gtgcgtcctc cccattacga
      481 gaagacctac tccttattcc atgagtttgc gtcaaagcct agatccctta gtagctgctc
      541 atgattaatc tagg
//
LOCUS       DADQDV010000235          534 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.247, whole genome shotgun sequence.
ACCESSION   DADQDV010000235 DADQDV010000000
VERSION     DADQDV010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..534
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.247"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>534
                     /locus_tag="J8S10_003185"
     CDS             <1..>534
                     /locus_tag="J8S10_003185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HAZ9631685.1"
                     /translation="DGFKACTDPRQAAYAFERNYERPAATHPERQDYAVNWYNKFKDL
                     KPGGATGEAGLKHLESLIGQRIGNGQCYGLSAEYSGYLGGCGMGAGTKYGLTHVIGNT
                     SAASDIGIAYDWSAVGWKVIQNPRYDQLVVGAIINWARGGQVGSWFADGTYGHTGVIR
                     GLANGRMQTYEQNTELG"
BASE COUNT          163 a           80 c          137 g          154 t
ORIGIN      
        1 tgatggattt aaggcctgta ctgatccaag acaagcagca tatgcttttg aacgaaacta
       61 tgaacgtccg gcagcgacac atcctgaacg tcaagattat gcagttaact ggtataacaa
      121 atttaaagat ttaaaaccag gaggagctac tggagaagca ggactaaaac atttagagtc
      181 tttgattgga caacgaattg gcaatggtca gtgttatggc ttgtctgcag aatattcagg
      241 atatctgggt ggttgtggca tgggtgctgg aacaaaatat ggtttaactc atgtgatagg
      301 aaatacttct gcagcatctg atattggtat tgcctatgat tggtctgctg ttggttggaa
      361 agtgattcaa aaccctagat atgatcaatt agtagttggt gcaattatta attgggcaag
      421 aggtggacaa gtgggttcat ggtttgcaga tggaacttat ggacatactg gcgttatccg
      481 aggcttagct aatggtcgta tgcaaactta tgaacaaaac acagagttag gtat
//
LOCUS       DADQDV010000236          530 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.248, whole genome shotgun sequence.
ACCESSION   DADQDV010000236 DADQDV010000000
VERSION     DADQDV010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 530)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 530)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..530
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.248"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            312..428
                     /locus_tag="J8S10_003186"
     CDS             312..428
                     /locus_tag="J8S10_003186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010768364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HAZ9631686.1"
                     /translation="MIGLNAISAKYCKFKAFVEKFTERQTDKIIQYHITYTD"
BASE COUNT          224 a           50 c           69 g          187 t
ORIGIN      
        1 taataaagaa ttgaacttct gagaaaacaa agaatctttt ttcttttttt gaattgactc
       61 atggattggc gttaaaattt tattttgaaa aagttatttc tggtttaact caaaaaaaga
      121 gatatgaatc taatagtgat agaaaggatg ttatttttca tgaaatggtt gttttagatt
      181 taatacatat aactaataaa tgctattgaa tgtatttaaa ctaattaaca aaagaatttg
      241 aattgttaat aaaatccaat aaaatatatt aataaagtag atagaaataa aaaaacaaag
      301 actaaacata tataattgga ttaaacgcaa tatctgcaaa atattgtaaa tttaaagcct
      361 ttgtagaaaa atttactgaa agacaaactg ataagattat tcagtatcat attacctata
      421 ctgattaaaa ttttttgaaa cgggatacta aataaaaaat ttatttataa cagaactaat
      481 tatttaatgc ggatgcgcca atacttggtc ctgcaagagc tatttatttt
//
LOCUS       DADQDV010000237          524 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.249, whole genome shotgun sequence.
ACCESSION   DADQDV010000237 DADQDV010000000
VERSION     DADQDV010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 524)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 524)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..524
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.249"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>524
                     /locus_tag="J8S10_003187"
     CDS             <1..>524
                     /locus_tag="J8S10_003187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAZ9631687.1"
                     /translation="YFKSEKDTSSLTLTLEEGVEPDKVTSKVINQLKEKGSLKHLGEY
                     EVLDTAMLTKGIGQILSTITYFITAVAGISLFIAGVGVMNMMYISVSERTKEIGIRRA
                     LGATRKSIMLQFLLEGLILTLSGGLIGYLLGMALAYSVGSLIKVNVSLDLFTILLAVG
                     VSSVIGLVFSVMPA"
BASE COUNT          155 a           73 c          120 g          176 t
ORIGIN      
        1 ttattttaag tctgaaaagg atacatcgtc tctaacgtta actttagagg aaggagttga
       61 acctgacaag gtgacctcta aagtgataaa ccaattgaaa gaaaaaggta gtttgaaaca
      121 tttgggggaa tatgaagtgt tagatacggc tatgttaacg aaaggaattg gtcaaatcct
      181 cagtacgatc acttatttta taacagctgt agcaggtata tctttattta tcgcaggggt
      241 aggtgtaatg aacatgatgt atatatctgt atctgaacga acaaaagaga tcggtataag
      301 aagagcccta ggagctactc gaaaatcgat tatgctgcag ttccttttag aaggtttgat
      361 tttaactctt tcaggagggt taattggcta tttattagga atggctcttg cttatagtgt
      421 tggttctttg ataaaggtaa acgtgtcact tgatctattt actattttac tagcggttgg
      481 ggtatcttcg gttattggac tggtcttttc tgtaatgccc gctt
//
LOCUS       DADQDV010000238          514 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.250, whole genome shotgun sequence.
ACCESSION   DADQDV010000238 DADQDV010000000
VERSION     DADQDV010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..514
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.250"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(107..>514)
                     /locus_tag="J8S10_003188"
     CDS             complement(107..>514)
                     /locus_tag="J8S10_003188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_465591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HAZ9631688.1"
                     /translation="GTPENHFSNQISLNVYSRGMGGLGLPGDLSSVSRFVKATFTKMN
                     AASGDSESESISQFFHILGSVEQQKGVCDTGEGKYEYTIYSSCCNVDKGIYYYRTYED
                     SQITAVNMNKEDLDRHELVSYPVIKEQQINYVN"
BASE COUNT          162 a          103 c           78 g          171 t
ORIGIN      
        1 atcatccata aaatggactt tgtctacagt ctgagacacg acctaaagat cgtgtctaat
       61 tatgactgta tcagaaaata tgataccaaa cggatctatt cattaattaa ttgacatagt
      121 ttatctgttg ctcttttatg actggataac tgaccaattc atgacgatcc aagtcttctt
      181 tattcatatt tacagcagta atttgactgt cttcatacgt acgataataa taaatccctt
      241 tatcaacgtt acagcaagaa gaataaatcg tatattcgta ttttccttct ccagtatcgc
      301 atactccttt ttgttgctcg actgagccta gtatatgaaa aaattgactg atactttcag
      361 attctgaatc acctgatgca gcattcattt tagtaaatgt ggcttttaca aatcgagaaa
      421 cagaagagag atctccaggt aagcccaatc ctcccatccc acgactataa acattcaagc
      481 tgatctggtt tgaaaaatga ttttctggtg ttcc
//
LOCUS       DADQDV010000239          509 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.251, whole genome shotgun sequence.
ACCESSION   DADQDV010000239 DADQDV010000000
VERSION     DADQDV010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..509
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.251"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
BASE COUNT          228 a           70 c           81 g          130 t
ORIGIN      
        1 aattccttag gcagcttttg ctgtgtagaa aggaataaat aataacgaaa gttcaaaagc
       61 taatgccgac tattctagac attaaagaag acgaaaacga acgataaaga aagaaaagtt
      121 atgaataatc gtttattgaa aaaaacttga aaaaatacaa aaaattcgtt gaccaagcta
      181 aatttagttg gtatattatt acttgtccaa aagacagaag aaaatattta ttcaaaaaca
      241 taacaaaaaa gttattgaca tgttactaac gacatgataa gataactgag tcgttaaaaa
      301 agaaccactt gcgaagcttg attctatcga aaaaaacttc aaaaaagttc ttgacaaata
      361 acaaacgata agttatgata aatgagttgc cgaaagattt cgaaaaacga aatcgaaaaa
      421 aacttttaaa aaagagttga caatcgcttg tctctctgat atgatataaa agttgctacg
      481 gcagccaaaa atgaatcggg aaacactct
//
LOCUS       DADQDV010000240          504 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.252, whole genome shotgun sequence.
ACCESSION   DADQDV010000240 DADQDV010000000
VERSION     DADQDV010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..504
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.252"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            50..>504
                     /locus_tag="J8S10_003189"
     CDS             50..>504
                     /locus_tag="J8S10_003189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAZ9631689.1"
                     /translation="MTYTHLTPNELVMIEAYFHQETPVAIVAKQLKRGRQTIYNVYNF
                     LKCGGTALEYFEQYKENKRRCGRTEIIFPAEEKEYIEKRSTEGWTPDVIIGRAERTFS
                     CSVSTLYRRFKTGEFNVLHLPMQGKRKPNGYKEKRGKQAFKRNISERKK"
BASE COUNT          189 a           95 c           98 g          122 t
ORIGIN      
        1 acactcaaat tgtaataccc gctaaagcat acaaggagag tgaacataaa tgacttatac
       61 ccatcttaca ccaaacgagc ttgtaatgat agaagcatat tttcatcaag aaactccggt
      121 tgctatcgtt gcgaagcagc ttaaacgtgg acgccaaaca atttacaatg tctataactt
      181 tctcaaatgt ggtggaacag cacttgaata ctttgaacaa tacaaagaaa ataagcgacg
      241 ttgtgggaga accgaaatca tttttcctgc tgaggaaaaa gaatacattg aaaaaagatc
      301 aactgaaggt tggaccccag acgtcattat tggccgtgca gagcgaacct tctcttgttc
      361 agtaagtacc ctctatcgcc ggtttaagac gggagaattc aatgttttac atttaccgat
      421 gcaaggaaaa cgaaaaccaa atggttataa ggaaaaacgt ggaaaacagg cattcaaaag
      481 aaatatttct gaacgtaaaa aaga
//
LOCUS       DADQDV010000241          493 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.253, whole genome shotgun sequence.
ACCESSION   DADQDV010000241 DADQDV010000000
VERSION     DADQDV010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..493
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.253"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(54..>493)
                     /locus_tag="J8S10_003190"
     CDS             complement(54..>493)
                     /locus_tag="J8S10_003190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAZ9631690.1"
                     /translation="KKAEGSPCFLLYQTFPGIGALTAALLLGELGDITRFKTHKQLNA
                     FVGIDIRRYHSGKYTGQDRINKRGNPKARKIIFFTIRNMIRQQRAAPNHIVDYYYKLK
                     KQPIPKKDKVATVACMNKLLKCMHAMVRAHTEYDYAYAVSVDH"
BASE COUNT          133 a           92 c          115 g          153 t
ORIGIN      
        1 tcgtaaaaaa ttttcgatct gggcaaagaa gtggtatact gtaagtggtt tagttaatgg
       61 tccactgaga ccgcgtacgc atagtcgtac tctgtatgtg ccctaaccat agcgtgcata
      121 catttcagaa gcttgttcat acaagcaact gtggcaacct tatctttctt agggataggt
      181 tgctttttta atttgtagta ataatcgaca atatgattag gagctgcgcg ttgctggcga
      241 atcatatttc gaatggtgaa gaaaataatt ttccgtgctt tgggattacc acgcttattg
      301 atgcggtctt ggccagtata cttacctgaa tgataccgtc ggatgtcgat tccgacaaag
      361 gcattcaatt gtttatgggt tttaaatcgt gtgatatctc ctaattcacc gagcaataaa
      421 gcggctgtga gtgcgccaat cccagggaac gtttggtaca acaaaaagca aggagagcct
      481 tcggcttttt tga
//
LOCUS       DADQDV010000242          470 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.254, whole genome shotgun sequence.
ACCESSION   DADQDV010000242 DADQDV010000000
VERSION     DADQDV010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.254"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>470
                     /locus_tag="J8S10_003191"
     CDS             <1..>470
                     /locus_tag="J8S10_003191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3-like element IS1485 family transposase"
                     /protein_id="HAZ9631691.1"
                     /translation="ALSKRGIQISRRKISRIMKNRGLKSSYTVAYFKVHHSTCNEAKT
                     TNVLNRKFLRDNPLEAIVTDLTYVRVGKKWNYVCFILDLFNREILGYSCGEHKDAVLV
                     KKAFSRIKQPLTEVEIFHTDRGKEFDNQAIDELLTTFDINRSLSHKGCPFDNAV"
BASE COUNT          167 a           78 c           88 g          137 t
ORIGIN      
        1 aagccttatc aaaacgaggc attcagatca gccgacgaaa aattagtaga atcatgaaaa
       61 atagaggatt aaaatcgagc tatactgttg cttattttaa agtacatcat tctacttgca
      121 atgaagccaa aacgacaaac gtattgaatc gtaaattctt aagagacaac ccattagaag
      181 cgatcgtaac agacttgact tatgtacgag tcgggaaaaa atggaattat gtctgtttca
      241 ttttggatct gttcaatcga gaaattctcg gctattcttg tggagaacat aaagatgccg
      301 ttctagtaaa aaaagcattt agccgtatca aacaacctct gacagaggtt gagatttttc
      361 atactgatcg tggaaaagag tttgataacc aagctattga tgaattatta acaacttttg
      421 acatcaatcg atcattgagt cataaaggct gtccttttga taatgccgta
//
LOCUS       DADQDV010000243          462 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.255, whole genome shotgun sequence.
ACCESSION   DADQDV010000243 DADQDV010000000
VERSION     DADQDV010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.255"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..430)
                     /locus_tag="J8S10_003192"
     CDS             complement(<1..430)
                     /locus_tag="J8S10_003192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAZ9631692.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRA"
BASE COUNT          132 a           92 c           59 g          179 t
ORIGIN      
        1 ctgctcttaa acgaataact tcttcttcaa gagactcatc tttaagtttt ttaggaatgt
       61 ttagcttgga attcatacta atttttctgc cccttttttg gctctcaagt gaagaagcac
      121 cgccttcttc atattgctct atccatttac ttagagttct atttgaaccg atattaaatt
      181 ttttagcagt ttcttggata gaaagaccat ttgtttccat atattctata acatcaagtt
      241 taaattttgt agtgtagctt ttgccacctc caaccaagcc ttcccaacca tgatagttat
      301 aaatccttac ccaatgtcta accagtgtac gatttatttg atatttatgt gcaagatatt
      361 tgtagccgcc ttcgttattt aaatagtctg aaactacttt tttcttaaaa acaaatgtat
      421 atttccgcaa aaaaagcacc ccttttaatt agatttctag tc
//
LOCUS       DADQDV010000244          460 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.256, whole genome shotgun sequence.
ACCESSION   DADQDV010000244 DADQDV010000000
VERSION     DADQDV010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.256"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(20..91)
                     /locus_tag="J8S10_003193"
     tRNA            complement(20..91)
                     /locus_tag="J8S10_003193"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56..58),aa:Glu,seq:ttc)
     gene            complement(113..200)
                     /locus_tag="J8S10_003194"
     tRNA            complement(113..200)
                     /locus_tag="J8S10_003194"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(164..166),aa:Ser,seq:gct)
     gene            complement(225..298)
                     /locus_tag="J8S10_003195"
     tRNA            complement(225..298)
                     /locus_tag="J8S10_003195"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(262..264),aa:Ile,seq:gat)
     gene            complement(312..382)
                     /locus_tag="J8S10_003196"
     tRNA            complement(312..382)
                     /locus_tag="J8S10_003196"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(348..350),aa:Gly,seq:tcc)
     gene            complement(384..459)
                     /locus_tag="J8S10_003197"
     tRNA            complement(384..459)
                     /locus_tag="J8S10_003197"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(424..426),aa:Asp,seq:gtc)
BASE COUNT          132 a          128 c          108 g           92 t
ORIGIN      
        1 taaaactata ttaaattaat gacccgtacg ggattcgaac ccgtgttacc gccgtgaaag
       61 ggcggtgtct taaccgcttg accaacgggc caggtaaaac aaaatattga aacggagaag
      121 gagggatttg aaccctcgcg ccggtttccc gacctacacc cttagcaggg gcgcctcttc
      181 agccacttga gtacttcccc aaaaccaata agattttgta ctaatgggcc taaatggact
      241 cgaaccatcg acctcacgct tatcaggcgt gcgctctaac cagctgagct ataggcccat
      301 aaaaaactaa aagcgggtga cgagaatcga actcgcgaca acagcttgga aggctgtggt
      361 tttaccacta aactacaccc gcatggcggt tccgacggga atcgaacccg cgatctcctg
      421 cgtgacaggc aggcatgtta acccctacac cacggaacca
//
LOCUS       DADQDV010000245          447 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.257, whole genome shotgun sequence.
ACCESSION   DADQDV010000245 DADQDV010000000
VERSION     DADQDV010000245.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 447)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.257"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            22..>447
                     /locus_tag="J8S10_003198"
     CDS             22..>447
                     /locus_tag="J8S10_003198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010890625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="HAZ9631693.1"
                     /translation="MIESYYLQHNKPVEIANRMGRAIQTIYNVVNKFKQGKTALDYWH
                     QYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKERSVSCGMRTLYRLFSK
                     GIFDIDTLPMKGKRKPNGHQEKRGKQQYQRSIHDRPDNYP"
BASE COUNT          166 a           79 c           86 g          116 t
ORIGIN      
        1 cttaccatag acgaactgac aatgatagaa tcatattatc ttcaacataa taagccggtt
       61 gaaatcgcta accgaatggg acgtgctata caaactattt ataatgtagt caataagttc
      121 aagcaaggca agactgctct tgattattgg caccagtata aagaaaataa gaaaaaatgt
      181 ggtagaaaag tcattcaatt acctgctcat gaagtagatt acattaaaga gaaagtcact
      241 cttggttgga cgcctgacgt cattatcggg cgaaaagaaa ggtctgtttc atgcggtatg
      301 agaacacttt atcgtttatt ttctaaagga atatttgata ttgacacact accgatgaaa
      361 ggtaaaagaa aacccaatgg ccatcaggaa aaacggggaa aacaacagta tcagcgctca
      421 atccatgatc gacctgataa ttatcct
//
LOCUS       DADQDV010000246          405 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.258, whole genome shotgun sequence.
ACCESSION   DADQDV010000246 DADQDV010000000
VERSION     DADQDV010000246.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 405)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 405)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..405
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.258"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..382
                     /locus_tag="J8S10_003199"
     CDS             <1..382
                     /locus_tag="J8S10_003199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAZ9631694.1"
                     /translation="KEICDDFKAVYQANSKEEANTFLSGMIEKWKKNYPKVTQSLIEN
                     QDLLTFYDFPPSIRRTIYSTNLIESFNKQIKRYSRRKEQFQNEESLERFLVSIFDTYN
                     QKFLNRSHKGFQQVTDTLVSMFTE"
BASE COUNT          157 a           72 c           63 g          113 t
ORIGIN      
        1 aaaagaaatc tgtgatgact ttaaggctgt ttatcaagct aactcaaaag aagaagcgaa
       61 taccttctta tccggcatga ttgagaaatg gaagaaaaac tatcctaaag tgacgcagtc
      121 actcatagaa aaccaagact tattaacttt ttatgatttt ccacctagca ttcgtagaac
      181 catttactca accaatctaa tcgagtcttt caataagcaa attaaaagat acagccgtag
      241 aaaagagcag tttcaaaatg aagaatcact agaacgcttt ctagtcagca tttttgatac
      301 atacaatcaa aaatttctaa acagaagcca taaaggtttt caacaggtaa ccgatacatt
      361 agtttcaatg tttactgagt aactaattat tttgcaggag gacaa
//
LOCUS       DADQDV010000247          404 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.259, whole genome shotgun sequence.
ACCESSION   DADQDV010000247 DADQDV010000000
VERSION     DADQDV010000247.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 404)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.259"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>404
                     /locus_tag="J8S10_003200"
     CDS             <1..>404
                     /locus_tag="J8S10_003200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631695.1"
                     /translation="KLKSSDFNVGYHGSLTSDNEKLHFTSDGTGSIIMFTRINTPQLA
                     SGKTYTLSAKVRFDEGTTGAIDKLRLVYRTSPGEKILLEANSTNITTDDVGKEITIKG
                     TANVNYQITNLDRFYMSISFVDRDKINGGFKL"
BASE COUNT          147 a           57 c           82 g          118 t
ORIGIN      
        1 aaactaaaat cgagcgattt taacgttggt taccacgggt cactaacttc ggataacgaa
       61 aagctacatt ttacttctga tggtacagga agcattatta tgtttacgcg tattaataca
      121 cctcagcttg ctagtgggaa aacctatact ctgagtgcga aagttcgatt tgatgaagga
      181 actacaggag ctattgataa attacgtttg gtgtatcgta catcaccagg agaaaagata
      241 ttattggaag caaatagtac aaatattaca acagatgatg tagggaaaga aataacaatc
      301 aaaggtacag ctaacgttaa ttatcaaatc acaaatttag atcgatttta tatgagtatt
      361 agctttgttg acagggataa aataaatggc ggatttaagt tgta
//
LOCUS       DADQDV010000248          367 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.260, whole genome shotgun sequence.
ACCESSION   DADQDV010000248 DADQDV010000000
VERSION     DADQDV010000248.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 367)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 367)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..367
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.260"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>367
                     /locus_tag="J8S10_003201"
     CDS             <1..>367
                     /locus_tag="J8S10_003201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAZ9631696.1"
                     /translation="KIPHFSTFGKNYVRRFRETTVFEDIFAYILEQAVKAGFVTEDNL
                     YLDSTHIKANANKHKFTKEMTHDEAKAYQDELEDEINRQRIEAGKRPFTLDLEKEVKL
                     KERKISKADPESGYYVKGER"
BASE COUNT          137 a           61 c           80 g           89 t
ORIGIN      
        1 aaaatccccc atttctcaac ttttggaaag aattatgttc gccgatttag agaaacgacg
       61 gtgtttgagg atatttttgc ctatatttta gaacaagcag ttaaagcagg ttttgtaaca
      121 gaggataatt tgtatctgga ttctacccac atcaaagcta acgccaataa acataagttt
      181 acgaaagaaa tgacccatga tgaagcgaaa gcctatcagg atgaattaga agatgagatc
      241 aatcgtcaac gaatagaggc tggaaaacgc ccttttactt tggacttaga aaaggaagtg
      301 aagctgaaag aaagaaaaat aagtaaagct gatccggaaa gcggctacta cgtcaaaggc
      361 gaacgag
//
LOCUS       DADQDV010000249          333 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.261, whole genome shotgun sequence.
ACCESSION   DADQDV010000249 DADQDV010000000
VERSION     DADQDV010000249.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 333)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 333)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..333
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.261"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
BASE COUNT          124 a           54 c           59 g           96 t
ORIGIN      
        1 ttaagattaa tgacactaaa ttaacagact atacgtagta tctatttgct atgaccatat
       61 cttatatcca taagtcaact cagccggact aaaagggcta atcttactag aacacaagct
      121 gcacttgata tgcaaattaa ccctgaatcg gaaaggtgct taaattggat attaacggag
      181 ggataaagta aaatttatct ctagggaatg tttagaaagg atccaagttc cttaacaagt
      241 gacaattagt aatgtagtaa caacgatagg ttgtatgccg aacatttcaa tttgatacgt
      301 ataaaagacg atttcaagct catccgtgat aaa
//
LOCUS       DADQDV010000250          299 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.262, whole genome shotgun sequence.
ACCESSION   DADQDV010000250 DADQDV010000000
VERSION     DADQDV010000250.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..299
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.262"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>299
                     /locus_tag="J8S10_003202"
     CDS             <1..>299
                     /locus_tag="J8S10_003202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAZ9631697.1"
                     /translation="TIVGIHHKSAVITLVERLSKAIIALKPEGRKAVDIENSINEWLQ
                     SVPKNLFKSITFDCGKEFSNWKSISNTNDIDIYFADPGTPSQRGLNEHSNGLLRK"
BASE COUNT          102 a           63 c           54 g           80 t
ORIGIN      
        1 acgattgtcg gcatccacca taaaagtgcc gtcatcacac tcgttgagcg actttcaaaa
       61 gccattatcg ccttgaaacc agaaggccgt aaggcagttg atattgaaaa ttcgattaat
      121 gaatggcttc aatccgtacc caaaaatctt ttcaaatcaa ttacctttga ttgtggaaaa
      181 gaattctcta attggaaaag tattagtaat acgaatgata ttgatattta tttcgcagac
      241 ccaggaacgc cttcccaacg gggattaaat gaacattcaa acggactcct ccgaaaaga
//
LOCUS       DADQDV010000251          297 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.263, whole genome shotgun sequence.
ACCESSION   DADQDV010000251 DADQDV010000000
VERSION     DADQDV010000251.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..297
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.263"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
BASE COUNT          105 a           33 c           46 g          113 t
ORIGIN      
        1 gactacctgt attagtcctc ttttttgacc agattttgac cagtctattt tacattctaa
       61 tatattcata tgagctaatt ttatgattaa atggtaagtt tttccttgtt tgttttagtt
      121 taaactagtg tgtaattcaa aaatctatat ggaaggatct gtggggtaaa tcattataca
      181 aaagtaaaat tttacttatt aacaggctgt agaaatataa aaaagaacta aaatttaact
      241 aaattatgtg ctattcttaa ggaaagccaa gtgtatgaga aagtttctga gaatata
//
LOCUS       DADQDV010000252          295 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.264, whole genome shotgun sequence.
ACCESSION   DADQDV010000252 DADQDV010000000
VERSION     DADQDV010000252.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 295)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 295)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..295
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.264"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
BASE COUNT          105 a           51 c           43 g           96 t
ORIGIN      
        1 tctataattt ctaggactga tggaaatttt ctatctgtcc tagttttttt gtaaaaaaac
       61 aaaaagacat acaaaatttc cggtagaata gagtctccta caacatcatt ctgggggaat
      121 tcttgtatgt ccatgaatca ttttatcaaa caactcttta ctattaaaga ctcaaatatc
      181 caaattcaat cctttgaaga aactttttat aaaagcagaa aaagtatcgt tattgaggga
      241 actctgatcc gtacctacag acgttgtccg tgttgtaaag attctacaaa gcaaa
//
LOCUS       DADQDV010000253          292 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.265, whole genome shotgun sequence.
ACCESSION   DADQDV010000253 DADQDV010000000
VERSION     DADQDV010000253.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..292
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.265"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..185
                     /locus_tag="J8S10_003203"
     CDS             <1..185
                     /locus_tag="J8S10_003203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAZ9631698.1"
                     /translation="YTFETLQQLDLELFDYVNWWNHLRLHGTLGYETPVGYRNQRLAQ
                     RILDNELGCANASEAV"
BASE COUNT           83 a           63 c           69 g           77 t
ORIGIN      
        1 aatacacatt tgaaacctta caacaattgg atttggagtt atttgactat gtcaattggt
       61 ggaaccacct tcggttgcac ggtacacttg gctacgagac accggttggt taccgtaacc
      121 agagattggc gcagcgaatc cttgataatg agctcggatg tgctaacgct agcgaggcag
      181 tctaacttta actgttagct cctgccgaag atcgtcacat ccgaggaggc tcattgtcaa
      241 ggacaatcgg aatagcatac ggaaagaagt tctgcacctt ataaaatttg tc
//
LOCUS       DADQDV010000254          281 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.267, whole genome shotgun sequence.
ACCESSION   DADQDV010000254 DADQDV010000000
VERSION     DADQDV010000254.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..281
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.267"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            10..>281
                     /locus_tag="J8S10_003204"
     CDS             10..>281
                     /locus_tag="J8S10_003204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAZ9631699.1"
                     /translation="MQGVIAMMSKNNTNGRNQFAMLTIDDLVPQDHLVRKIDAALDFE
                     FIYPIVEATYSDLGRPSIDPVILIKLVFIQYLFGIRSMRQTIKEVDT"
BASE COUNT           84 a           53 c           56 g           88 t
ORIGIN      
        1 tgaaaacgaa tgcaaggagt gatagctatg atgtctaaaa acaatacgaa tggtagaaat
       61 caatttgcga tgcttacgat tgatgatcta gttcctcaag atcatctcgt tcgaaagatt
      121 gatgccgcgc ttgattttga atttatttat ccaatcgtcg aagccactta ctccgattta
      181 ggtcgcccaa gtatcgatcc agtgattctg atcaaattgg tgtttattca gtatttattc
      241 ggtatccgtt ccatgcgaca aaccattaag gaagtcgata c
//
LOCUS       DADQDV010000255          269 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.268, whole genome shotgun sequence.
ACCESSION   DADQDV010000255 DADQDV010000000
VERSION     DADQDV010000255.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 269)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 269)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..269
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.268"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
BASE COUNT           83 a           47 c           68 g           71 t
ORIGIN      
        1 caagaggttg tgagcctgcc gtttaactcc gagtcacaag gagcaatttc aaaaaacagc
       61 ttctcaggtt tgttgactat tgtgacttgt gaccgaggag ttggcaggag aacaccgttt
      121 aaggaagagg ttgtaaaatc agcggtttga cctgagtatt agagatacaa aacggaaaaa
      181 tagcttctca tattttgccg ttttttgagc taataccgaa ggacagctga ttgaacaccg
      241 tttattcgga aaaagggact gtgacacga
//
LOCUS       DADQDV010000256          267 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.269, whole genome shotgun sequence.
ACCESSION   DADQDV010000256 DADQDV010000000
VERSION     DADQDV010000256.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..267
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.269"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(35..>267)
                     /locus_tag="J8S10_003205"
     CDS             complement(35..>267)
                     /locus_tag="J8S10_003205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAZ9631700.1"
                     /translation="LKNLPETLDAQLRTKLQNLLTYEEGIYNAMIYPYSNGKIEAKIP
                     HIKTLKRLSYGFKSFENMKIRIFLINQLIQVK"
BASE COUNT           78 a           39 c           47 g          103 t
ORIGIN      
        1 tagaaggact gaccttctgt ctcagatttt tttgttattt cacttgaatc aattgattga
       61 tcaaaaaaat cctgattttc atgttctcaa atgatttaaa tccataagat aatcgtttca
      121 gtgtcttgat atggggaatc ttggcctcta ttttgccatt agaatacggg taaatcatag
      181 cattgtaaat accttcttca tacgttaaaa ggttttgaag tttcgtgcga agttgtgcat
      241 caagtgtttc aggaagattt tttaata
//
LOCUS       DADQDV010000257          265 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.270, whole genome shotgun sequence.
ACCESSION   DADQDV010000257 DADQDV010000000
VERSION     DADQDV010000257.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 265)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 265)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..265
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.270"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..218)
                     /locus_tag="J8S10_003206"
     CDS             complement(<1..218)
                     /locus_tag="J8S10_003206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631701.1"
                     /translation="MFKPLIDSYSAVLKKFKGNDIGATINEEVNIERLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDI"
BASE COUNT           68 a           57 c           44 g           96 t
ORIGIN      
        1 aaaatatcgc ctatgagtgc atagatgaag tttcgttgct gtacggtgaa acgtctagga
       61 tcaataaaac gaatttcaat gactcgatcg ccatcatagc cgtcatacat cgttttcagc
      121 cgttcgatat ttacttcttc gttgattgtt gcaccaatgt cgttaccttt aaatttcttt
      181 agtaccgccg agtatgaatc tattagtggt ttaaacactc atatcacttc tcttttgttt
      241 cttctctgta ctgatcttca agcca
//
LOCUS       DADQDV010000258          262 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.271, whole genome shotgun sequence.
ACCESSION   DADQDV010000258 DADQDV010000000
VERSION     DADQDV010000258.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 262)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 262)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..262
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.271"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
BASE COUNT           96 a           36 c           50 g           80 t
ORIGIN      
        1 atatcactgg ggttttatga acagaactgg tacttaatcg gttttgcagg ctaagaaatg
       61 aatataggaa ttttcgtgtg gatcggatta aaagcatttg catagaagaa gagctctgtc
      121 aaagccatga tggctctttg gaacaaatat taaaacaaat gctttcatat aaaaaactat
      181 atgccctaca atgccgttgt aaaaattggg gaaaagggat atattgattt tatatctttc
      241 tcaaaataaa tataaaagcc ct
//
LOCUS       DADQDV010000259          258 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.272, whole genome shotgun sequence.
ACCESSION   DADQDV010000259 DADQDV010000000
VERSION     DADQDV010000259.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..258
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.272"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            98..>258
                     /locus_tag="J8S10_003207"
     CDS             98..>258
                     /locus_tag="J8S10_003207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAZ9631702.1"
                     /translation="MTYTHLTTDELVIIESYFKMNQSVAKTAHCLNRSRQTIHKVYLF
                     FKQGKSALE"
BASE COUNT          100 a           48 c           39 g           71 t
ORIGIN      
        1 attacgccga ttgtaaaatt aagctagaca actaaaaaag tcatttgtgc tacactcaaa
       61 atagttccga ccaaagaatt ataaggagtg agtacaaatg acctataccc atcttacaac
      121 ggatgaactt gtaataatag agtcttattt caaaatgaat caatctgttg ctaaaactgc
      181 ccattgcttg aatcgttcaa gacaaacgat ccataaagta tatctgttct tcaagcaagg
      241 aaaatcagcc ttagaata
//
LOCUS       DADQDV010000260          253 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.273, whole genome shotgun sequence.
ACCESSION   DADQDV010000260 DADQDV010000000
VERSION     DADQDV010000260.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 253)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 253)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..253
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.273"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            28..>253
                     /locus_tag="J8S10_003208"
     CDS             28..>253
                     /locus_tag="J8S10_003208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HAZ9631703.1"
                     /translation="MLGNIQQETGGTFDPDTVQIGGPAYGLVQWDGSSYPLVGPATWD
                     GKVYVQNLFNAAGIKEPITSLDAQVRLLIWT"
BASE COUNT           80 a           40 c           58 g           75 t
ORIGIN      
        1 ggatttacga aacaatctgc atgtggaata ttggggaaca ttcaacaaga aacaggagga
       61 acttttgatc ctgatactgt tcaaataggt ggaccagcat acggattagt tcagtgggat
      121 ggttcttcat atcctcttgt tggtccagca acatgggatg gaaaagttta tgttcaaaac
      181 ttatttaatg ctgcaggtat taaagaacca ataacgagct tagatgcaca agttcgattg
      241 cttatttgga cat
//
LOCUS       DADQDV010000261          243 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.274, whole genome shotgun sequence.
ACCESSION   DADQDV010000261 DADQDV010000000
VERSION     DADQDV010000261.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 243)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 243)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..243
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.274"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            39..>243
                     /locus_tag="J8S10_003209"
     CDS             39..>243
                     /locus_tag="J8S10_003209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HAZ9631704.1"
                     /translation="MRSSKYTEHYTDTFITFKEIMRTVSNIYHNCVPDKIKNRRNTDQ
                     LKQRDTVIIACVIWGIINGYTSQR"
BASE COUNT           96 a           40 c           40 g           67 t
ORIGIN      
        1 atagtagtct caaaactccc aagaaatgag gactacatat gcgttcatca aaatatactg
       61 aacattatac agatactttt ataacattca aggaaattat gagaactgtt tctaacatat
      121 accacaattg tgtaccagat aagattaaaa accgaagaaa tactgatcaa ctgaagcaac
      181 gcgatacagt gattattgct tgtgttatat ggggcataat taatggctat actagccaaa
      241 gag
//
LOCUS       DADQDV010000262          236 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.275, whole genome shotgun sequence.
ACCESSION   DADQDV010000262 DADQDV010000000
VERSION     DADQDV010000262.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 236)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 236)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..236
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.275"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>236
                     /locus_tag="J8S10_003210"
     CDS             <1..>236
                     /locus_tag="J8S10_003210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HAZ9631705.1"
                     /translation="LVKNLAMFGLGLYIFAGEDMPEDVSMLEPATQRSKKLFLDALQL
                     VANKYEKSIDEAIVALTDAASITADDSKWTKRDLG"
BASE COUNT           77 a           40 c           55 g           64 t
ORIGIN      
        1 cttgtaaaaa atctagcaat gtttgggcta gggctatata tatttgctgg cgaagatatg
       61 ccagaagatg tctcgatgct tgaaccagct actcaaagaa gcaaaaagct attcttggat
      121 gctttacaac tggttgctaa caagtacgaa aaatcaattg atgaagcaat tgttgcattg
      181 actgatgcgg cttctataac cgctgatgac agtaaatgga ccaagagaga cttggg
//
LOCUS       DADQDV010000263          233 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.276, whole genome shotgun sequence.
ACCESSION   DADQDV010000263 DADQDV010000000
VERSION     DADQDV010000263.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 233)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 233)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..233
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.276"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
BASE COUNT           79 a           35 c           45 g           74 t
ORIGIN      
        1 tgagaaaaag catggaatgc gctgcatcag gtatcgaggc ttagaaaaaa atcaggtgca
       61 tacgatgctt gtttttgccg aaatgagtct gaaaaaattg gtcacttagc agtgggagca
      121 tatgtcttca tattttttat tatacaaaaa tagacaaaag tatcagtcta cactcttagt
      181 aaagaggaaa ctgatacttt tgtctacagt atgatatttc ttacatctac ttt
//
LOCUS       DADQDV010000264          232 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.277, whole genome shotgun sequence.
ACCESSION   DADQDV010000264 DADQDV010000000
VERSION     DADQDV010000264.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..232
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.277"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
BASE COUNT           89 a           33 c           32 g           78 t
ORIGIN      
        1 aaggatatgg aagtattacc atggatttac aataaattaa atcaggagca atttaacaaa
       61 ttactataca acctaaatgg aaataatcaa ttttacaaaa acagtaattt tccgcctttt
      121 atttctaatc tgttagactt ttataatcag aaattccaag tgaatttacg taaacattat
      181 agtgggcttc tatatccaaa tgcagtgact atggatcagg gttttcaatt aa
//
LOCUS       DADQDV010000265          224 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.278, whole genome shotgun sequence.
ACCESSION   DADQDV010000265 DADQDV010000000
VERSION     DADQDV010000265.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 224)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 224)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..224
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.278"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>224
                     /locus_tag="J8S10_003211"
     CDS             <1..>224
                     /locus_tag="J8S10_003211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HAZ9631706.1"
                     /translation="PSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAA
                     ESQTPAKPAAEPTVDTESAGSSSEGVFQFK"
BASE COUNT           70 a           47 c           58 g           49 t
ORIGIN      
        1 ccgtcacctg ttacaggaac ggttaaaaat gtgattgttc cagaaggtac cgtagcaaat
       61 gttggggatg tattagtaga aatcgatgca ccaggacacg aagacaatga aggggacagt
      121 ggtgtagccg cagaatccca aactccagct aaaccggctg ctgaacccac tgttgataca
      181 gaatcagctg gatcgtcaag cgaaggagtc ttccaattta agtt
//
LOCUS       DADQDV010000266          219 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.279, whole genome shotgun sequence.
ACCESSION   DADQDV010000266 DADQDV010000000
VERSION     DADQDV010000266.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..219
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.279"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            1..219
                     /locus_tag="J8S10_003212"
                     /pseudo
     CDS             1..219
                     /locus_tag="J8S10_003212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
BASE COUNT           91 a           42 c           42 g           44 t
ORIGIN      
        1 tacgccttct tctttcgata aatggatgaa gcaagcacaa tcaacgggct cattcaaaga
       61 aagagacaac ttaacaccag aacaagcaga attgatcgca ctaagaaaga aaaataagca
      121 actcgaaatg gagaatgata ttttaaagca agcggcgctg atattcggac gaaaagacaa
      181 gtaattgatg ccaacaagca taaatattcc atatcagcg
//
LOCUS       DADQDV010000267          218 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.280, whole genome shotgun sequence.
ACCESSION   DADQDV010000267 DADQDV010000000
VERSION     DADQDV010000267.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 218)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 218)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..218
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.280"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..>218)
                     /locus_tag="J8S10_003213"
     CDS             complement(<1..>218)
                     /locus_tag="J8S10_003213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="holin"
                     /protein_id="HAZ9631707.1"
                     /translation="NKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIITGF
                     GAFLGSVLGVSNRTYKMFSAESEEGGNK"
BASE COUNT           64 a           55 c           36 g           63 t
ORIGIN      
        1 tttgtttcct ccttcttcgc tttcagccga gaacattttg taggttcgat ttgatacacc
       61 caacacactc cctaaaaacg cgccaaaacc agtaatgatg acaacacaga tatctgtgta
      121 ctgccaattg agcgctttac caactaaccc cacgaaagta gctagtgcgg gaataattac
      181 cagtgcgaac cattttagta cttcgaacgt tttattat
//
LOCUS       DADQDV010000268          218 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.281, whole genome shotgun sequence.
ACCESSION   DADQDV010000268 DADQDV010000000
VERSION     DADQDV010000268.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 218)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 218)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..218
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.281"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>218
                     /locus_tag="J8S10_003214"
     CDS             <1..>218
                     /locus_tag="J8S10_003214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAZ9631708.1"
                     /translation="FIAKNCQVSLTTVIRTLKEFKSYLPKQSKRILPRVLMVDEFRSH
                     ASIEDKMSFICADGETGQLIDVLPTRKL"
BASE COUNT           66 a           39 c           45 g           68 t
ORIGIN      
        1 ttttattgcg aaaaattgtc aggtatcttt gaccaccgtt attcgtacgt tgaaagagtt
       61 taaaagctac ttaccaaagc aatctaagag gattctcccc agagtattga tggttgatga
      121 atttcgttcg cacgcttcca tagaagataa aatgagcttt atttgcgcag atggcgaaac
      181 aggacaatta attgatgtct tgcctacgcg taaattgc
//
LOCUS       DADQDV010000269          211 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.282, whole genome shotgun sequence.
ACCESSION   DADQDV010000269 DADQDV010000000
VERSION     DADQDV010000269.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 211)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 211)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..211
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.282"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            55..>211
                     /locus_tag="J8S10_003215"
     CDS             55..>211
                     /locus_tag="J8S10_003215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAZ9631709.1"
                     /translation="MSKRTRRTFSQEFKQQIVNLYLAGKPRVEIIREYELTASAFDKW
                     VKQSKTSG"
BASE COUNT           84 a           33 c           43 g           51 t
ORIGIN      
        1 gacagaaaaa ttaaggtgtg tagactagaa gaaaacatac caggaggaat ttttatgtct
       61 aagagaacac gaagaacttt ttcacaagaa ttcaagcaac aaatcgtcaa tctttactta
      121 gctggaaagc cacgtgtaga aatcattcga gaatatgaac taacggcttc agcatttgac
      181 aaatgggtaa agcaatctaa aacgagtggt t
//
LOCUS       DADQDV010000270          210 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.283, whole genome shotgun sequence.
ACCESSION   DADQDV010000270 DADQDV010000000
VERSION     DADQDV010000270.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 210)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 210)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..210
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.283"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
BASE COUNT           76 a           35 c           37 g           62 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcacgac aaaataaaca
       61 actgagagga cgatatgcta tatgaatgat tctatcaaaa aaatgctgcg attaatagag
      121 aaagatttga tgattacaga ggtctcttac gagacctttc agaagaaaaa gacgttgatc
      181 gtcgatgctg ttttctcacc tgctccccat
//
LOCUS       DADQDV010000271          201 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.denovo.286, whole genome shotgun sequence.
ACCESSION   DADQDV010000271 DADQDV010000000
VERSION     DADQDV010000271.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 201)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 201)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..201
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.denovo.286"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..>201
                     /locus_tag="J8S10_003216"
     CDS             <1..>201
                     /locus_tag="J8S10_003216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAZ9631710.1"
                     /translation="PIENESDLEEIVQEEFIRNRKAYGTRKLKKCLAKRGLQLSRRRI
                     GRIMKRRGLTSTYTIAHFKGQRT"
BASE COUNT           64 a           44 c           50 g           43 t
ORIGIN      
        1 ccgatcgaaa atgagtccga cttagaagag atcgttcagg aagagtttat tcgaaaccga
       61 aaggcttacg gtacccgaaa attgaagaag tgtttagcaa agcgtgggct tcaactcagt
      121 cggcgccgaa tcggtcgaat catgaaacgc cgcggattga catctaccta tacgatcgct
      181 cattttaaag ggcaacgaac a
//
LOCUS       DADQDV010000272        20754 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.guided.054, whole genome shotgun sequence.
ACCESSION   DADQDV010000272 DADQDV010000000
VERSION     DADQDV010000272.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 20754)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20754)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20754
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.guided.054"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            8..1216
                     /locus_tag="J8S10_003217"
     CDS             8..1216
                     /locus_tag="J8S10_003217"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HAZ9631711.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            1370..1825
                     /locus_tag="J8S10_003218"
     CDS             1370..1825
                     /locus_tag="J8S10_003218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631712.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            2187..2462
                     /locus_tag="J8S10_003219"
     CDS             2187..2462
                     /locus_tag="J8S10_003219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631713.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            2475..4553
                     /locus_tag="J8S10_003220"
     CDS             2475..4553
                     /locus_tag="J8S10_003220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HAZ9631714.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            4713..6599
                     /locus_tag="J8S10_003221"
     CDS             4713..6599
                     /locus_tag="J8S10_003221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAZ9631715.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            6611..7558
                     /locus_tag="J8S10_003222"
     CDS             6611..7558
                     /locus_tag="J8S10_003222"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HAZ9631716.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            7578..8105
                     /locus_tag="J8S10_003223"
     CDS             7578..8105
                     /locus_tag="J8S10_003223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAZ9631717.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(8168..8821)
                     /locus_tag="J8S10_003224"
     CDS             complement(8168..8821)
                     /locus_tag="J8S10_003224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HAZ9631718.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            8953..9795
                     /locus_tag="J8S10_003225"
     CDS             8953..9795
                     /locus_tag="J8S10_003225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAZ9631719.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            9953..10849
                     /locus_tag="J8S10_003226"
     CDS             9953..10849
                     /locus_tag="J8S10_003226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAZ9631720.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            10852..11565
                     /locus_tag="J8S10_003227"
     CDS             10852..11565
                     /locus_tag="J8S10_003227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HAZ9631721.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            11585..12103
                     /gene="msrA"
                     /locus_tag="J8S10_003228"
     CDS             11585..12103
                     /gene="msrA"
                     /locus_tag="J8S10_003228"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAZ9631722.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            12100..12327
                     /locus_tag="J8S10_003229"
     CDS             12100..12327
                     /locus_tag="J8S10_003229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HAZ9631723.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            12479..13030
                     /gene="lepB"
                     /locus_tag="J8S10_003230"
     CDS             12479..13030
                     /gene="lepB"
                     /locus_tag="J8S10_003230"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAZ9631724.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(13113..13655)
                     /locus_tag="J8S10_003231"
     CDS             complement(13113..13655)
                     /locus_tag="J8S10_003231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HAZ9631725.1"
                     /translation="MNTLIAKDVFRLPEMNARLLSTSALLLALDVILYKIAIGPAYFQ
                     ITFGFLSMALMGYLYGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLF
                     LYHKKINLPSVIAAQLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQI
                     MVVYSFIKTLEARKVFKRAV"
     gene            complement(13892..14290)
                     /locus_tag="J8S10_003232"
     CDS             complement(13892..14290)
                     /locus_tag="J8S10_003232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAZ9631726.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            14550..15410
                     /gene="ylqF"
                     /locus_tag="J8S10_003233"
     CDS             14550..15410
                     /gene="ylqF"
                     /locus_tag="J8S10_003233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HAZ9631727.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            15403..16170
                     /locus_tag="J8S10_003234"
     CDS             15403..16170
                     /locus_tag="J8S10_003234"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HAZ9631728.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            16226..17083
                     /gene="dprA"
                     /locus_tag="J8S10_003235"
     CDS             16226..17083
                     /gene="dprA"
                     /locus_tag="J8S10_003235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HAZ9631729.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            17205..19283
                     /gene="topA"
                     /locus_tag="J8S10_003236"
     CDS             17205..19283
                     /gene="topA"
                     /locus_tag="J8S10_003236"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HAZ9631730.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            19252..20628
                     /gene="trmFO"
                     /locus_tag="J8S10_003237"
     CDS             19252..20628
                     /gene="trmFO"
                     /locus_tag="J8S10_003237"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HAZ9631731.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
BASE COUNT         7227 a         3566 c         4332 g         5629 t
ORIGIN      
        1 tggaaaaatg aaattaaaac aattacctct ggaataccaa aaggcaattc cagttctgaa
       61 aaaattagag aatgcaggat atgaagctta ttttgtaggt ggaagtgttc gtgatatctt
      121 gctgaaccag ccaatccatg atgtggatat cgcaacaagc gcatttccag aagaaatcaa
      181 acagcttttt ccaaaaacga tagatattgg gatcgaacat ggaactgtgt tggtattaga
      241 aaatgatgaa caatatgaga tcaccacatt tcggacggaa tcaacttatc aggactaccg
      301 tagaccagat catgtcgaat tcgttcgttc gttggcagaa gatttgaaaa gaagagattt
      361 tacgatcaat gcgtttgctt tgaaagaaga tggagaaatc atcgatttgt tcgatggtct
      421 gcaagatcta gaagaacaga tcttgcgagc tgtaggcaat cctcatgagc ggttccatga
      481 agatgcctta cgaatgatgc gcgggttgcg ttttgtcagt caactagggt tcaaattaga
      541 ggaagaaacc ttctacgcca tcaaagaaaa ccacgagcta ttaggtaaaa tatctgtaga
      601 acgtataaat gtggaattca tcaagatgct cttgggaaat gaacgggccg cgggaatcca
      661 tgcatttatt gaaacagagt gctacatttg ctgtcccggt ttgaaagaag aaggcgaagc
      721 acttttacgt tttgctgaat taccatccgt cccattgaaa gaagagagcc aagcatgggc
      781 attattgatc agccaactgg atctaaaaga aaatgagatt cgttcctttt tgaaatcgtg
      841 gaagtgttct aaccaaatga ttaaagacgt tcaagcactt gtccaaggac tacgacaacg
      901 agaaactgga gctttggaac cattcgaatt gtacttctta ggcaaaaaac atgcactgca
      961 agtagaagaa ttgatgatct attttgacga aacacctcag atggatgccg taggagaatc
     1021 ctatgatcgt ttacctatca agtcattaag cgaattagca gtagatggta aaatcttgct
     1081 agaagaaact ggaaaaaaac ctggtaagtg ggttagtgaa gctttgcaat tagctgaaaa
     1141 agccgtcgta gaacaaagaa taaaaaatga taaaaaacag gttttggatt ttttatcgaa
     1201 agaaaaattg atttaaaaaa cactagactg tatctgctca gctttgttgg ctacttaaag
     1261 tgggcagata cgtcattaga agaaaaaaca taagatgtga ccacttacat aaatttgtgc
     1321 taaactgagg tagtacaaga ataaattaca tcataaagga gtctttttaa tgagtaaaga
     1381 aatgacagcg ctaaaatttt attttagaaa tggagaaacc tggacgatca accgccgtca
     1441 tatcggcgat ctttggatca aacaaatcac aacaagtttt ggacgaatca atggcagtga
     1501 atttgttgaa atccatccgt gtgctggatt taaaatcgaa atcttccatg aaggggacgc
     1561 agttgcgaca catgatatca acctaggcgg actggaaatg ggcatgttta atcgcgcatt
     1621 gaaatacgaa gatatcgagc gaatggaaat cctttaccga aatggcacac ctgatcttgt
     1681 gtacttccca tatctagata aaggaacaga aggattagac aatcaatatc aatcaacaaa
     1741 aatcagcgaa aaaacaggta acttgtatat cgtgatcaat ccagatcaac gtgtagaaga
     1801 tgtatacggg gaatttttcg aataaatcga tttttacgca aaaatgaggc tgtgaaagag
     1861 atgtgtctta ttactactga taggctgtct cttccacacc gtttattcag aataagggac
     1921 tgtgacaaga tttttgtcgc agccccattt ttttgttgtg ataaaagaac aagaaaggca
     1981 ggaatgggaa agtaaacatc cttttgtcag aaacttttat ctttcttaag ttttacttga
     2041 tatctgatac tatttggaat agaatgaggc gttgaaaaat ttatggaaat ttctaactag
     2101 caataaacga tgaaacaatg aaatattttt catccaaaaa gaactttgct ataatgatgg
     2161 aagtttgtgt ataggagatc tggaaaatga gagagagttt tgaacaacaa aaaaaactgt
     2221 tgcatgatcg ctatggcgcc ctttcgatgg atgaccgccg tcaaatactt tgtaagttgc
     2281 gtaaaagaaa tatattgatg tatcgtcagt tggaacgtct gaaacatgat ctgcttcgtt
     2341 tggagtcaaa acgtgtacag tgtgaattag aggggaacca aacacaggtt gaagtagtcg
     2401 aaaccaaaat tttaaagaaa aaagaacaat ttttaaaaat gcttacacaa aataaaaaat
     2461 aaaggggatg gacgatggaa tttgctgagt tagttattgt atttgcagta acgatcacct
     2521 tatcgaacat agctagccgc attttgccaa tgattccagc tccactgatc caaattttcc
     2581 ttggagtggt attaggtctg acagagtggg gacaatcaat cgattttgaa cctgaattgt
     2641 tcttagttat gattattgca ccattgttat ttagagaagg agaaaaagca gatatttctt
     2701 cgattctcaa aaatttcggg acaattttgt tcttggcatt tggaggagtc attttgaccc
     2761 ttgtcggggt aggtgcgacg ttatcattcc tgttgccaag tgtcccactt gctgcctgct
     2821 ttgcttttgg agcagcgtta ggtccgacag atgcggtagc agtcagttct ctttctggac
     2881 gagtgaatat ccctaaaaag gcgatgcata ttttggaagg agaaggtctt ttgaatgatg
     2941 catctggtgt tactgccttc cagtttgctc ttggtgcgct gatcaccgga tctttttcag
     3001 cagtaaacgc ggggatgagt ctagtagttt ctagtattgg gggagctttg atcggctttt
     3061 tgcttgtctg gttcaaacaa aaaataattc atttgatcga aaaagcatca gcacaagatg
     3121 tcacagggta tctgctgatc gaacttttgc ttccttttct agcctatgta ttggcagagg
     3181 catttgatgt atctggaatc attgctgcag tggcagcagg tattctccaa gcttctggtt
     3241 ttaggaaaat ctctgtgttt gatgcagaat tgtcgagctt gtcccacagt acatggacaa
     3301 ctattgcttt tacactgaat gcattagtat ttatattttt aggaatcgaa ttgacgcaag
     3361 tgttctcgcc agtatgggga gacggtttat atccaaacgg tcttttatta gcgattatcg
     3421 tattaatctc tgtcatgctt tttgtgatca gattcatttc tatcagtctt ttttatgtat
     3481 tcaaagatgg cagtaaaaag ttcaaaaaac agttgaacga gatcttgatc ttaacatttg
     3541 gcggtgtaaa gggaacagtc agtttggcta cgatttttat tttgccattt tcaatcaata
     3601 atatgatgtt ttaccagcgg tctttgcttt tgtttctgac ggcgggtgtc atcttagtga
     3661 ctttggtcat agggatcatt gtcttgccta tgctgacgga aacagaggaa gcgaaaagca
     3721 cggatttgaa tgctttgatg attttagaag aggtcgttga agttttgcga aaagaaataa
     3781 aggaaattga tcgtaataca aaagaatttt tagccactga agcagtgata gaaaattatc
     3841 aagaacggat acgtgatctg tacttggaag atttaaccga tgatgaaaag caagaagtac
     3901 aagaaataca agcactgatt ttgtcgatcg aacgggatgg attggatgaa agttatcgtt
     3961 cgggcaagct ttcttctaat ggttatcgtt tttactcccg ttttctttct cgattcgaac
     4021 attctatcac aagccagatt ttgtctttta tcggcttttg gttcattgtt gtccgtaggt
     4081 taatgcgaat cgttctccat ccgaaaatgt tttggcaaag aagatatgct gatcgtcaga
     4141 catttattag tgatgaagat atccaagaaa tcagagagac atatcaaaaa aatactcagt
     4201 tgattattga aagtttagat aacttgactg atatttatga tgaaacgatg gttcaatttt
     4261 ttatccagca acgcaaactt gaaggaataa aaatgaactc ggggaatttg atttcttcgt
     4321 ggatgatcca gcaagatagt ctgtttacga aaaaaatgct aagaggttat tatcttgaaa
     4381 gaaaaatcat tgatgaatac gaagttgctg aaaaaatcac gacgttttct gcgaacagct
     4441 atcgcaggaa tatcaatttg ttagaatctt atacgatgaa caaaccatct gataactttt
     4501 ctttccgatt tgcgtttcga gcaaagtcaa aaaaaacgag tccaataaaa taaaaaggta
     4561 aaaattttca agttttataa aaaacaaaac atatcagaac aggatcgaat cggtcctgtt
     4621 ctttttttga gaacacaaaa agaacaaata ccaaaaaaat tttcctgaag ttcactattt
     4681 ttatgataca atatccaaga taaggaggga acatgttgaa agaattaaaa gtaactgacc
     4741 tcaaaaaaac ttatggtgaa aaagatttgt ttgaccagat ttcttttttg gtccacgaaa
     4801 aagaccgtat cgggttgatt gggacgaacg ggacgggtaa aacaagtctc ttaaatatta
     4861 ttgccggtat cgatagcagc gacggtgatc ggcaaacagt gttttatcca actgattacc
     4921 gtattggtta tctttctcaa gcagctgaat tttccgatga attaactgtt ctccaagcag
     4981 tctttcaagg aaacagcccc ttgatccaaa ctgttcgagc atatgaggaa gcattgatcg
     5041 aactagggga aaacggagaa gaccctgatg tgcaaaaacg ttatgctaaa gcagaagaac
     5101 aaatgaataa agaagatgct tggactacag ataccaacgc aaagattatt ttgcaaaaat
     5161 taggaatcag tgaattagat aaaaaaatca gtactttatc aggtggtcag aaaaaacgag
     5221 ttagtctggc gcaagtgttg attgatgaac ccgatttact attactagac gaaccaacaa
     5281 accatttaga ttatgaagcg atcgagtggt tggaaaacta tttgaaacaa taccgtggcg
     5341 cactattgat ggttacccac gatcgttatt ttctagatag agtagcaaac cgaatcttcg
     5401 aactttcatt tggaaaatta tacgagtata aaggaaatta tgaagcttac gtcttagaaa
     5461 aagcagaacg tgatcgtgta gaagtagaac aagaagaaaa gcgcaagcgg ctttataaac
     5521 aggaattagc ttggatgagg gctggcgtac aggcacgtgg caccaagcag caagcacgga
     5581 tcaaccgttt cgaagatcta aaggagaact tgtaccaagt aaaccaagaa gatgatttag
     5641 agctgaacct agcgacacaa cgtttaggga aaaaagtact ggaaatcaaa gatggcagtt
     5701 accgtataaa tgaccaaaca ctgctagaac atttagattt attgattcaa tctcgggaaa
     5761 gactaggtat tactggtaaa aatggtgcgg gaaaatcgac attgcttaat attctagctg
     5821 gcagaattcc cctggatagc ggtacaatgt ctatcggtga aacggttcat cttgcgtatt
     5881 atacacaaga aaatgaagaa atggcaccag ataaacggat gattgcttac ttacaagaag
     5941 ctgctgaaga agcaaaaaca gcagatggca gtcaaatcgg agtagcagaa ttacttgaac
     6001 gatttttatt tccaagattt atgcatggga cactgatagg caaactttca ggcggagaaa
     6061 aacgccggtt atttttgttg aaactgctga ttcagcaacc taatgtttta ttattggatg
     6121 aaccgaccaa tgatttggac atagcaacat tgacgatttt ggaagattat tttagaagtt
     6181 ttccaggtgc tgtgatcact gtttcccatg accgttattt cttggacaag gtagcagata
     6241 agttattagt attccaagga aacggaaaac aagaacttta ttacggaaac atgtccagtt
     6301 atttactgaa gcaaaaagag acccagcagc ctgctgaaaa agcgaaacca aaaatacaga
     6361 gcaaggaacc tgctgaaaag aagaaattat cttacatgga acaaaaagaa tgggaaacga
     6421 ttgaagatga gattgcagaa cttgaagaaa aaatctcatt gctccaagaa gagatgaatc
     6481 atcaaggaga taatttcact cgattacaag aattgcaaaa cgacgtatct gaaacagaag
     6541 cacaacttga agaaaaaatg gcacggtggg aatacttgag tgaatgggta gaagattagg
     6601 aggaaaaagg atggaacaag cgtatcttga cttaggaaga aaattgttgg aagaagggca
     6661 tcgtaaagaa gacagaacag gcacaggcac attaagctta ttcggatacc aaatgcggtt
     6721 tgatctgcaa aaagggtttc ctttgttaac aacgaaacga gtaccttttg gattgatcaa
     6781 aagcgaattg ctttggtttt taaaaggaga tacgaatatc cgctatctat tacaaaataa
     6841 aaaccatatt tgggatgaat gggcatttga acgctacatc aaaagtccag actataatgg
     6901 accagatatg actgattttg gccatagatg tttgacagat cctgaattca atgaagaata
     6961 taaaaagcag agcaagcttt tttgcgagaa gatcctaacc gatgattcct ttgctgaaac
     7021 atacggcgat cttggacaca tctacggcta tcaatggcgt cactgggaaa caaaagacgg
     7081 tggctttatc gatcaaatca aacaagtgat cgaagcaatc aaaaagactc ctgattctag
     7141 aagattgatc gtttctgcat ggaatccgga agatgttcct agcatggctt tgcctccttg
     7201 tcatacgatg tttcaatttt atgttcaaga gggacggcta agctgccaat tgtatcaacg
     7261 cagtggggat gtgtttctag gcgttccgtt caacattgca agttatgcgt tgctgactca
     7321 cctaattgca catgaaacag gtttagcggt tggcgaattt gttcacacat taggagatgc
     7381 tcatctttat atcaatcata tcgaacaaat gaaagaacaa ttgagccgag aaatacgcgc
     7441 atttccgact ttagttttga atcaggaaaa gcagtcagta tttgattttg agatggaaga
     7501 tatccaatta gaaggatatg acccacatcc ggcgatcaaa gctcctatcg ctgtttagaa
     7561 tcagaaagga tgagaaaatg ttagctgcaa tttgggcaca ggatgaaaac ggattgattg
     7621 gaaaagaaga ccgtcttcct tggcgtttgc caaatgatct gaaattcttc aaacaaatga
     7681 cagaagcaaa tacactagtg atgggacgaa aaacattcga agggatgggt agccgtccgt
     7741 tgccgaatcg tcagacgatt gttttgacga gagattcttc ctataaagca gaaggcgtgc
     7801 atgtcatgca tagtgtggaa gacgtgcttg ctctggaaaa agaaacagac ggtatctttt
     7861 tcatcgctgg agggtcagct gtttatcaag aatttctgcc attttgtacg atattatacc
     7921 gtacagtcat ccatcatgta ttcgatggag atgcttattt tccacctgtt gactggtctg
     7981 attggtcact gatcaatact agtcaaggag aaatggatga aaaaaatcgt tatccgcatc
     8041 aatttgaaac gtatcagcgt aatgagaatc ctgtaaaaag cgggacaggc gaattgacga
     8101 tataaaaaag ctatggatag actagctgtt atttagagct gtcccatcca tagctttatt
     8161 ttttttatta agtaaagaat aaaacagaga agtacataaa acctgcacct aacataacaa
     8221 acaaatgcca aacaacatgc atatagcgga tagaattcaa gctataaaag aatgcgccta
     8281 tcgtgtaaga aagcccgcct gctaccatca aaataacacc agtcattcca agagagtgat
     8341 aaagaggaac agcagccacg acacagagcc accccataaa aatatagatg atcgtagata
     8401 cttttgatac tctctcccgt ttatgcaacg tcaacgcttt atatataatg ccaagaatcg
     8461 caaacaacca gattaataca aataaagtcc aacctagcca tcctcggata ctcagcaaac
     8521 aaaaaggagt ataacttcct gcaatcaaaa gaaaaatcga actatgatcg aatacttgga
     8581 acaccttttt tgcttttgta aaaatcaatg aatgaaacaa agtagacgtt aaaaataaaa
     8641 gaatcatcat cgatccatag atagcataag agacaatatg gagggaggaa tgcaagtggg
     8701 caccttttac taaaagaacc actagtcccg cgatactcaa tccagtccca attccatggg
     8761 tgactgcatt aaacacttca tttaatattt catacgttcg attaaatttc gttttttcca
     8821 tgaaaacggc tcctttacta ggtgtaatta atgaaaaatc attatttgtc tgttatacta
     8881 aaaatagaaa ttgtcttaca tgtagtttaa catgaataag gcatcttgtt aaagaaagag
     8941 agagagaaaa taatgacaaa tgtaaaaatc gtaacagatt cttcatgtac gatggaaaaa
     9001 aatgtacgcg atgctttagg cattcgtgtc atgccgctat ccatcatgat cgacggaaca
     9061 gtatatcccg atgatgacca actagacggc gaaagattta tggaaatgat ggcgaaagca
     9121 aaaaatctgc ccaaaacaag ccaaccacca attggagaat tcatctcgat gtatgatgag
     9181 ctaggagaag acggcagtga agtgatttcg atccatatga caaaaggctt gagtggaaca
     9241 gtagaagcag caagacaagc cagtaatcta acaaaaacga aagtaacggt tatcgacagt
     9301 gataccactg accaaggatt atcttttcag gtaattcgag cagctgaatt agcaaaagaa
     9361 ggtaaaacag tagagaaaat ccttgaagaa gtcaaaaaag tacaagacaa tacaaaatta
     9421 tacatcggaa tatccacact agataacttg gtaaaaggtg gaagaatcag ccgaacaact
     9481 ggtttgctgt ctagtgtttt gaacatacgc gtggtgatga atttcgccca ttctgaatta
     9541 atccctgtaa ctaaggggcg aggaaagaaa acgttcgata aatggtttaa taatttgaaa
     9601 aatgaactga aagaattgcc aaatgtgcga caaatcggta tttcacatgc ggatgcaaaa
     9661 gaattggcgc aagaattcaa agagggtttg caagaattat tcccggacat gcatatccct
     9721 gtactgcata cgaatccggt tatcgctacg catactggta aagacgcgtt tgcaatcatg
     9781 tattatgtag attagtcgaa aagaggataa gccctcagcc tgaaaggctt gcagcttatt
     9841 ctctttttct ttataaaatt aggaaaataa ttgttttctt ttttcataaa gactaccttt
     9901 ttgataaaat ttttgataac attagaacca atcgaataca agaggtgaaa aaatgaaatt
     9961 aacgaaacga catttgatcc tcgttttgtt cccattatta attgcgatca tcatctatgc
    10021 aggtttagct gcttctatac cgaaagctgg cccactaatg aaaccagtaa ctactgtgag
    10081 agaagatcca aataaaaaag aaaaacttca ctacatagct atcggagatt cgctgactga
    10141 aggagtagga gatcaaacca agcaaggagg attcgttccc cttgtcgcaa atgatctaaa
    10201 agaccgttat aatttgaccg cggttgaaac agaaaactat ggtgtaaatg gtgaacgaag
    10261 tgaccagatc ttaaagcgag taaaaacaaa agaagaaatt cgaaacaata tcaaaacagc
    10321 tgattttatc acactgactg ttggcggtaa tgatttgatg aaagttatcc aaaataattt
    10381 attcgggtta acggtcaatt cctttaaaaa gccactgaaa aactatcagg aaaatgtcac
    10441 agaactattg gaagaatttc gatccctcaa taaaaccgca cctatttaca ttttaggcat
    10501 ctacaatcca ttttatttga actttcctga gatcactgac atgcagacaa ttgttaacaa
    10561 ttggaacaaa ggaacagaaa cggtgacaaa aaaaatgccg aactgctact ttatcccaat
    10621 caatgatttg ctttatcaag gattgaatca ggaagtaggt gtcacagaag aaggaacaga
    10681 tcaaacaact agcacgacag aaaatctaaa tggcatcaaa aataatgtgc tctatgaaga
    10741 agatcatttc catccaaata atttaggtta tcaattgatg gcaaatgcag tgagagatca
    10801 gctgatcgag acacaaaacc aatggttaga gaaggaggat gatcaataaa catgaaaaca
    10861 agatctgacg tatcttcaaa caaaacaaag aaaacaaatt actggaaatt cgccttcctt
    10921 atccttcttg gggtagtact tggttcgacc gtatttttag gcagccgtat ttttgctaat
    10981 cgggaaccag aactcccaga aataccagct cttacggaaa gacaaggaga tcctgtctta
    11041 acgatcaatt caaataaaga aaaagtcaat caaatcatca gctttttcct tagtgagtat
    11101 caaaaagata gtgatattga atataaattt tatttggaaa atgaagcact actcaatggt
    11161 actttcgaag tactaggttt tcctatcgat ttctatttat attttgatcc gtatgtgatg
    11221 gaaaacggaa atgtccaact aaaagctaga agtctttcta tcggaacatt gagtttgcca
    11281 atcaaagatg tgatgaatat gatcaagaga aactataaat taccagattg gatcgaagtc
    11341 aatacagatg atctgactat catgcttagg ttggatcaat tccgaatgca aaacgggatg
    11401 tatattaaag cagataaaat cgacttagta aatgatgaca ttcggtttag tctatatttg
    11461 ccaaaagata cctctgatgc ttcaaacaac tcaaatacca acaaaactag caccagcagt
    11521 actgaaagca agacaaaaga aaataaaaaa tcatcggatg agtagtatta gagggggaat
    11581 cataatggaa cgagcaatat ttgcaggagg ctgcttctgg tgtatgatcc agcctttcga
    11641 cacgcttcct ggtatccata cagtgatgtc aggatatact ggagggcatg taccagatcc
    11701 gacttatgaa caagtaaaaa gccaaacgac tggacataca gaagcagtgg agattatcta
    11761 tgatccaaca ttgatttcat atgaacaatt agtagaactt tactggcagc aaactgatcc
    11821 aactgacgct ttcggacaat tcgaggatcg cggtgacaat tatcgcccgg tgatctttta
    11881 tttgacagaa gaacagcgga tcattgctga aaaaagtaag aaacagttag ctgaaagtgg
    11941 acgtttcgaa cagccaatcg ttacaaaaat cgaaccagcc caaccatttt atctagcaga
    12001 agaagaccat caagagtatt ataaaaagca tcctgaaaat tttaaaagaa accatgcacg
    12061 ccgggctgcc tttatcgaag aaaattggag gaacgaaggg tgaatcgaag cttttttcat
    12121 tatttaatga cactgcgagg cggtggcaca catgatgctt tatctgtttt cgctacagaa
    12181 gccggtaaag acatccaatt tcctaagcac agctctagct acgaagaaat ttctaattat
    12241 ctggaactga atgtcgacta tttgccgtcc atggatatct ttgacgaagc atgggaaaaa
    12301 tatttagaaa ataatcatga catataagag atagttttgt actttatgat caaaaaagtt
    12361 ttttgtccaa tagcctaatt gaaagaatta tttttatttc agctatctag tcgcattttt
    12421 ttgatatttt tcttataata aagaaagaat gaaaaaaaga gggatggatt gatagagatt
    12481 gacaaaaaaa caacgctata ttaatcgctt ctggcttgta ttcaaatact tacttgtttc
    12541 tgtattcctt gcgttcatgt tgcggggatt tttattcatc ccggtaccag tggaaggcaa
    12601 ttcaatggaa aacgtgttga agcaaggtga tatggttgtg atggaaaaat tttcggagat
    12661 cagacgattt gatattgttg tttttcaatt agcagatggc acgatttata tcaaacgagt
    12721 aatcggtctt ccaggagaaa atgtcagcta ccaaaatgat caattgaaga tcaatgggaa
    12781 agtagttaag gaaccttatc taactaaaaa cctgaaatca gatcatgcaa atgcatccta
    12841 tacgacggac tttacactac aagagctaac gggacaatcc aagcttccgg aagataatta
    12901 ttttgtactt ggagataatc gaagagtttc aaaagatagt cgttcgtttg gcacgatcaa
    12961 taaaactgat attctaggta aagcaagatt tgtctattat ccacttgatg aaataaaatg
    13021 gatccagtga gaaacaataa agcgtgcagt ctgttgagac tgcacgcttt attgtttaat
    13081 ccaaaatcag tttactacct tagtacgtaa aatcaaacag ctcgtttaaa cacttttcta
    13141 gcctctaaag ttttgataaa tgaataaaca accattattt gaatagggat ttggatcata
    13201 ttcctgatga atctacctag aaaaattact ttgaaatctg caccaaacaa aacagacatc
    13261 agccaagaat tgataaaaag gctgactggg atcataatca ataattgggc agcgatgacg
    13321 gaaggcaggt ttatcttttt atgatataaa aataagccat taataaatcc accaaggaaa
    13381 gccgtgataa gaaaagcagc ttgaaacgtt cctgaaccaa atatcgtgaa atttaaagtg
    13441 ttcgacaaca tttcaagcaa accagcccag atcggtccat atagataacc cataagcgcc
    13501 atacttaaaa atccgaatgt gatttgaaaa taagcaggac caatcgctat cttgtataag
    13561 atgacatcaa gggctaataa aagagcagag gtcgacaaca atcttgcatt catttcgggc
    13621 aatctaaaaa cgtcttttgc aatcaaagtg ttcaaaatat tctctccttt gtcagttaat
    13681 aataaaagga taccataaaa tcaccaatgt gtcatgacac attggtgatt tacatacact
    13741 ggcatctaac aattaaaaaa agggtgagaa gactgctttt ataaactgta aaaaagagat
    13801 tgtacgaata aaaaaaatag aggcggagaa tacttatcgt atcatccgcc tttgtttttt
    13861 tgttataaaa aacgtcagat tagttatctg cttacatctt catccatacg ggttctaatg
    13921 tatttccgtc tagatcttgg acttctaatg aaaacatttc ttcttcaggc attcccatat
    13981 ctacttcgtg gaaagtacca ccattttctt ttgcaatttg agcaaatttt tttacttcat
    14041 ccgcattttc aacactaaac gaaatcaaag caccacttgt ttttttatta tcagctattt
    14101 ctttatcttt tataaatttt ttataaaaat catgagagag aagcattatc caaaaagtgt
    14161 catcccatac cattgaacca gcttcttcag tagaaaattc ttcatttttt ttaaaaccca
    14221 gcttttcata aaaagcaacg gaacgattga catcagcaac aggaaaatta acaaaaacca
    14281 tactattcat ttgtttcgtc tcctttctgt tttgttcgtc tatcatctct tatttaggaa
    14341 acgctgtcaa aaatttagat tcatatatag aaaccaaaat aaaaatttgc atcatcaaaa
    14401 aagtgaagat gtgatagaat gaggactggt tcactttcac ttaactaata gatggaattt
    14461 ctttataata aaaaagtgaa tttatattga aaaagaaaaa aacaagtaaa gccggggaat
    14521 attccggtat gaaaggaatg gagagaacaa tgaccatcca atggtttccg ggacatatgg
    14581 caaaagcccg acgagaagtt tctgaaaaaa tgaaatatgt ggacatcgta tttgaattgg
    14641 tagacgcacg attaccttta tcttctcgta atccaatgct agatcagatc attcagcaaa
    14701 aacctcgcct tgttttattg aataaagcgg atctggcaga tccacaacag acaaagctgt
    14761 ggcaagaata ttttcgtaaa caaggccatc ttgcattagc tatcacggca caagaaagta
    14821 aaggaattaa aggtctagta cctgcggcta aagaagcatt gaaagaaaaa cgggcaagag
    14881 atgctgctcg ggggatcaag cctcgcgcta ttcgggcaat ggtcttaggt attccaaatg
    14941 ttgggaaatc tacgttgatg aatcgactag taggcaagaa aattgcacag acaggaaata
    15001 agcctggcgt aacaaaaggt cagcagtggc ttcgtttagg taatgagttg gaattgttag
    15061 acacaccagg gattttatgg cccaaatttg aagatgaaga aatcggcaaa aaactagcgc
    15121 tgacaggcgc gatcaaagac cagcttgtcc atttagatga tttagcgatt tacggattag
    15181 acttttttgc ccgatattat tcaggaagaa tcagcgatcg ttatggttta tcaatcgagc
    15241 aagaagaaaa attggcaccg gaattactga tggatattac agcaaaacgt gggtataaag
    15301 aagactatga tcgtggcagc gaattagtcg tgcatgatat tcgtcaagga aaacttggac
    15361 gatacacact ggatcgttgc gaagaaatgg agcaaaaaag tgatgactga atccatccaa
    15421 agtatcaaag aacgattgaa aagcatacag agaatagatg atcctacact agaatcatta
    15481 agaaatgatc cacgcaaagg cgtgcagcaa gcactggctt cttttgaacg acgattgaaa
    15541 aaggaagcat taattaagga aaaatatgaa gaaatgtttt gctttgaaaa gcaagggtac
    15601 gcacaaggtc accaatggat tgccggcatt gatgaagtag gaagaggacc attagctgga
    15661 cctgtcgtgg cagctgcagt tatcttgccg aaaaatgaga tcatattagg gctgaatgac
    15721 tccaaacaat tatcagagaa aaagcgagaa cttctttatc aacaagttca agaaaaagcc
    15781 ctggcaatcg ggatcgggat cgttgatcag cagacaatcg atgatgtgaa tatttatgaa
    15841 gcaagtaaat tagcgatgat ccaagcagta gaaaaattgt ccattgtacc aagctatttg
    15901 ttgatcgatg cgatgacctt ggatttgcct attcagcagg aaaaaataat caaaggggat
    15961 gcacgatctg tgtcgattgc tgctgcaagt atcattgcta aagtatatcg agaccaattg
    16021 atgaaagaat atgacgtgct ttatcctgga tatggtttct cgcataatgc aggttatgga
    16081 acaaaggaac acttagaagg acttgaacga caaggaatta cgccaatcca tcgtaaaagt
    16141 tttgcacctg taaaaaaata tttacaataa aaaacagccg cttttacgta tcttattaga
    16201 aagagagacg aaaggcggtt ttatgatgta tcaaatagaa gaaaatttat tgaaacttgc
    16261 ttatacaaaa ggaatcagta gtcaaggaaa atgggcactt gctaactgga tgatgcagta
    16321 tccttataaa gaaatcggat ttgaagacat cattaagata ggtaaaataa ccaaacaccg
    16381 ggagctgttt cgcaaaagtt ggcaggaaat tcacgctaac tggggcaaaa tccaatcgaa
    16441 acagtcgttt atcacttgct ttgatcccaa atatccccct cagctgcttc acttgaccta
    16501 tccgccaatt gtactgtttt ataatggtga tctatcttta ctttcttgta acatgttaag
    16561 cgttgttggt ggaagacaca cttctgcttt agccaaaaaa acagtttatt atttactaaa
    16621 accagtgata gaagctggat atgtgatcgt cagtggctgc gcgaaaggga tagatacata
    16681 cggtcaccaa gcagcaatct ctcatggtgg acggacaatc gcagtcattg gaacagggat
    16741 agagcaagtc tatcctgctg aaaatcgtga cttgcaagag gtgattgcaa atgatcatct
    16801 tcttttgagt gaatatcctc ctcaatccgg cccgaaaaag cattgttttc caatgagaaa
    16861 tcggattatc gcagctttgt ctaaaggaac atgtgtcttt gaagccaaga aaaaaagcgg
    16921 ctctctgata acagcacagc aagcattgga tcttggaaga acagtttttt ctgttccagg
    16981 aaatatttta acagaacatt ctaccggatg tcatcatttg atccaagacg gtgcagtttg
    17041 cacggtttcg ggtgaagata tcttggcaga atttaaagaa taacaccata cttttcattt
    17101 gcttttcttg acaaacgttt tctgaatgga tatgattagc tacgatttgt atgaatcctc
    17161 ttttaatagt aggaacacga caatggaaag gagtccattc agtaatggcg tataaatatt
    17221 tagtgattgt agaatcacct gcaaaagcca agacaattga gaaatatctt ggacgaaact
    17281 ataaagtaat ggccagtgtt ggccatataa gagatttacc gaaaagtaaa atgggtatcg
    17341 attttgaaaa caattatgaa ccccattata tttctatacg cggaaaaggc gatgtcatca
    17401 aaagcctgaa agccgcagca aaaaaagctc aaaaagttta cttggcaagt gacccggata
    17461 gagaaggaga agcgattgct tggcatttag cgtacctact tgggttggat ctgaaagaaa
    17521 aaaatcgggt ggtcttcaat gaaatcacaa aagacgcagt caaagcagct tttaaggaac
    17581 caagaacgat cgatgtagat ttagtagatg cacagcaagc tcgtcgtacc ttagacagaa
    17641 tcgttggtta ttcgatcagt cctattctct ggcgtaaggt caagaaaggg ttaagtgcag
    17701 gacgtgtcca atctgtcgct ttaaaaatta ttattgaccg tgaaaaagag atccgagaat
    17761 ttgttccaga agaatattgg agcatcgacg gtaattttaa aaaagctcgc aagaaattca
    17821 aagcaaattt ctggggaatc gacggtaaga aaaagaaatt accagatgca caaagtgtaa
    17881 aagaagtcac tgctagaatt gatggaacag acttcgaagt taaaaaagta gaaaagaaag
    17941 agcgcaaaag aaaccctgcg aatcctttca ctacaagtag cctgcaacaa gaagctgccc
    18001 gtaagttaaa ctttcgaaca agaaaaacca tgatggtagc acagcaatta tatgaaggaa
    18061 tcactttggg taaacaagga acagtcggct tgattacata catgcgtact gattctaccc
    18121 ggattgccga tacagcaaaa gcagaggccg cagcatttat tgaagatacg tatggaaaag
    18181 aattttctag acatgatcac cgaaagatca aaaatgctca aggcgcacaa gatgcccatg
    18241 aagctgtgcg tccaacgagt gtgcttcgta caccagatga actcaaacaa tatttagata
    18301 aagatcaatt gaaactttat acattgatct ggtcacgttt tgtggctagt cagatgacac
    18361 cagctatttt agatacaatg aaagtgacat tagaacaaaa tggtgtcatc ttcattgcga
    18421 acggttcaaa aatcaaattc aaaggattca tgcaagtgta tgtggaaggt agagatgacg
    18481 gcaaagaaga gaaagaaaat attcttccag aacttgaaga aggcgatgta gtccaatctg
    18541 ttgatattga accaaaacaa cattttactc aaccaccagc acgttttagt gaggctacgt
    18601 tgattcgtgc actagaagaa aacggggtag ggcgaccttc cacttatgca ccaacacttg
    18661 atacgatcca aagacgctac tatgtaaaat tgacacaaaa aagatttgag ccgactgaac
    18721 taggagaaat tgtcaattca ttaatctgtg aattcttccc tcaaatcgtc gatatccatt
    18781 tcacagcaga aatggaagga gatttggata aaattgaaga aggcacggaa gcgtgggtca
    18841 aagtggttga tcgtttctat aaaccgtttg aaaaagaact gacgaatgcg gaagaaaaaa
    18901 tcgaaaaaat tcaaatcaaa gatgaaccag caggattcga ttgtgatgtc tgtggacatc
    18961 cgatggtgat aaaattaggg aaatatggga agttttatgc ttgcagtaat tttcctgatt
    19021 gtcggaatac gaaaccaatc gtaaaagaaa tcggtgtgac ttgcccagta tgtcatgaag
    19081 gacaagtcat tgaacgaaaa tctaagaaaa acagactatt ctatggttgt tcccgtttcc
    19141 cagaatgtga attcacttct tgggataaac cagtgggcag aaattgtcca aaatgtgacg
    19201 gatatctggt cgagaagaaa gtcaaaggcg gtaaacaagt agtctgtgta aatggagatt
    19261 acgaagaaga catccaaaaa taatagaaaa gaggttcttt cattgaaaat ggtaaatgtt
    19321 gttggagcag ggcttgccgg aagtgaagct gcttggcaga tcgcacaagc aggagtccct
    19381 gtccgtttat atgaaatgcg tccagtcaaa tcgactgagg cgcatcacac aagtaatttt
    19441 gctgaactag tatgttccaa ttcattaaga ggaaacagtt tggctaatgc agtagggtta
    19501 ttgaaagaag aaatgcgccg attgaattcg gtagtaatca cttcggcaga tgaaacagca
    19561 gtgccagctg gtggtgcctt agctgttgac cgcgattctt tttctgaaac aattacccga
    19621 aaagtcaaag agcatccatt agtaacagtg ataaacgaag aaattactga aataccggaa
    19681 ggaatcaccg tagtagcaac aggacctttg acttctcatc cattagcaga aagcatcaaa
    19741 gcattcaatg gttcagatgg tttttatttc tatgatgcag ctgcaccaat cgtagacaaa
    19801 gctacgatcg atatggataa agtatatttg aagtcccgct atgacaaagg agaagcagct
    19861 tacttgaact gtccgatgac agaagaggaa ttcaaagctt tccatgaggc actaatcaat
    19921 gccgaagtgg cagaacttaa atcttttgag aaagaaaaat attttgaagg atgtatgcca
    19981 attgaagtaa tggcacagcg aggattcaaa acgatgcttt tcggacctat gaaaccagtt
    20041 ggattggaag atcctaaaac tggcaaacgt ccttatgctg ttatccagct gcgtcaagac
    20101 aatgctgcag cttctttata caacatcgtg ggctttcaga ctcacttgaa atggggcgag
    20161 caaaaacgtg ttttccggat gattcctggg ttagaaaatg ctgaattcgt tcgctatggt
    20221 gtgatgcacc gaaacagctt tatgaattcg ccagaattgc tgaaaccgac ttaccaatca
    20281 acgaaacgcg aagatctgtt ctttgcaggt cagatgactg gtgtagaagg ctatgttgaa
    20341 agtgcagcga gcggactact tgctggaatc aacgccgcac gcttagcaaa agaaatggaa
    20401 ccagtcgagt ttccacaaga aacagctatt ggaagtatgg cttactacat tactcatgcg
    20461 gaaggaaaac atttccaacc gatgaatgcc aactatggtc tgtttcctga actgccagag
    20521 cgcattcgag acaaaaaagc aagatatgaa gcaattgcac aacgagcttt aaaagctaat
    20581 gaggcaataa aaacagaatt agaaaaaact gcaatcccaa atgagtaagg aaactccatg
    20641 aagagggtga gacggatagt ctcgctcttt ttcttgcgtt tttcttaaga atttctcaaa
    20701 caaaatgtga ggaattgcgc caattgtgaa caaacttaga aatattggtt aaat
//
LOCUS       DADQDV010000273        17965 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.guided.060, whole genome shotgun sequence.
ACCESSION   DADQDV010000273 DADQDV010000000
VERSION     DADQDV010000273.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17965)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17965)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17965
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.guided.060"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..263
                     /locus_tag="J8S10_003238"
     CDS             <1..263
                     /locus_tag="J8S10_003238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HAZ9631732.1"
                     /translation="SMYFQKKLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTP
                     FKPILSELLEFYDAENWAKRFITNDSTIYEQYEYDLSSVENK"
     gene            complement(413..1354)
                     /locus_tag="J8S10_003239"
     CDS             complement(413..1354)
                     /locus_tag="J8S10_003239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HAZ9631733.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            1480..2601
                     /locus_tag="J8S10_003240"
     CDS             1480..2601
                     /locus_tag="J8S10_003240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAZ9631734.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            2859..4361
                     /locus_tag="J8S10_003241"
     CDS             2859..4361
                     /locus_tag="J8S10_003241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HAZ9631735.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            4428..4955
                     /locus_tag="J8S10_003242"
     CDS             4428..4955
                     /locus_tag="J8S10_003242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAZ9631736.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            5166..6227
                     /locus_tag="J8S10_003243"
     CDS             5166..6227
                     /locus_tag="J8S10_003243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HAZ9631737.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            6230..7126
                     /gene="murQ"
                     /locus_tag="J8S10_003244"
     CDS             6230..7126
                     /gene="murQ"
                     /locus_tag="J8S10_003244"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HAZ9631738.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            7140..9122
                     /locus_tag="J8S10_003245"
     CDS             7140..9122
                     /locus_tag="J8S10_003245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAZ9631739.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(9187..9633)
                     /gene="nrdI"
                     /locus_tag="J8S10_003246"
     CDS             complement(9187..9633)
                     /gene="nrdI"
                     /locus_tag="J8S10_003246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HAZ9631740.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            9844..11268
                     /locus_tag="J8S10_003247"
     CDS             9844..11268
                     /locus_tag="J8S10_003247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAZ9631741.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            complement(11449..12222)
                     /locus_tag="J8S10_003248"
     CDS             complement(11449..12222)
                     /locus_tag="J8S10_003248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAZ9631742.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(12219..13124)
                     /locus_tag="J8S10_003249"
     CDS             complement(12219..13124)
                     /locus_tag="J8S10_003249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAZ9631743.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            complement(13278..13598)
                     /locus_tag="J8S10_003250"
     CDS             complement(13278..13598)
                     /locus_tag="J8S10_003250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HAZ9631744.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            14072..14758
                     /locus_tag="J8S10_003251"
     CDS             14072..14758
                     /locus_tag="J8S10_003251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HAZ9631745.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            14760..15704
                     /locus_tag="J8S10_003252"
     CDS             14760..15704
                     /locus_tag="J8S10_003252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HAZ9631746.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            15903..16547
                     /gene="pcp"
                     /locus_tag="J8S10_003253"
     CDS             15903..16547
                     /gene="pcp"
                     /locus_tag="J8S10_003253"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HAZ9631747.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            16626..17903
                     /locus_tag="J8S10_003254"
     CDS             16626..17903
                     /locus_tag="J8S10_003254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631748.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
BASE COUNT         5741 a         3188 c         3822 g         5214 t
ORIGIN      
        1 aatccatgta ttttcaaaag aaactagtga cggataatca agcgattgct cattatcatt
       61 tttatcgtcc tgaaaatatt tttttgcttc gagaacgtga tttagatgaa ttaccggaat
      121 ttctgcatac accatttaag ccaatcctat cagagctatt ggaattttat gatgcagaaa
      181 attgggcaaa acgatttatc actaacgatt ccactattta tgagcaatac gaatatgacc
      241 tctcctctgt tgaaaacaaa taaaaaacct acattttgaa gagattatgt actgaaacaa
      301 acaagcacaa ttcttatggc atcatgagag ttgtgttttc tttttgatct tttattgggc
      361 ttaaaaaaag agaaccagct gctgattcag ctgattctca tcagagagcc ttttattctg
      421 cgccaaggat tccttctttt gcatggacta attgggtcaa aaaggcacaa tatggtgtag
      481 caatatcata tttttgtcct tttcgccaaa tggcaccatt gatgtagtcg atttcagtca
      541 aacgatggtt tttgatcagg tcttggtaca tagatgggta atgcaacccg atgttgtcag
      601 gatcataagt agaagcaata tgttggtaca cttcttcttg atctagtatg attccttctt
      661 ttgctgcgat agaagcaaat tcagatacga ttgttcgaac catgctctct gccgcttttt
      721 gcgcgcctag ttcagcaata ttacaatcca aaatcgtgca taaaccattc aatgttccat
      781 ttacacaagc ttttcgccaa atggaataac gaacgttatg gctatagatc ggatttaaat
      841 ttgcttcttg aaagacttct acaacttttt ttgtaaatgc ttcgccttct ggttccaagt
      901 tctctagttc gatttctcca tcacctaaca atgtgacttt tccgggacca gctagaccag
      961 ctgtccacat cgtgatccca aataagatat ttttctttgg cacatatttt tccagtacat
     1021 cttcatgacc taatccattt agtaaacaca aaacataagt attgtcagta ataatggatt
     1081 ggatcgaaca aaacatatca tctaattgat tggcttttgt taatgctacg atcaagtcca
     1141 cgtgttcgtt gctttcgatg atttcttctg gtgaatagat tggcagtttt gcgaccactt
     1201 ctttaccgtt aaagtcagca atcaacccat ttgtacgaat ggcttcaatg tgagcaggcc
     1261 aacgatcgat caagaggacc tcatttccgc tttgatgtag catcaatccg attcggctgc
     1321 ccattgctcc ggccccagct attgcgattt tcatgttttt tctctccttt attcaatgag
     1381 ttccctttta gtatatagaa aaatggaaga aaatagcatt gttttgtttg aaaaaaatga
     1441 aaaaaagtgt cttacttaag aagaaagtga gggatacaga tggatatttt ggcggcaatt
     1501 gattcattta aaggaagtgc ttcttcattt gaactaaatc aggcagttct aaatggctgg
     1561 gaagatcgta aaggaagaaa aatcaatgtg ccgattgcag atggcggaga aaatactgca
     1621 gaagcaatct attacgcgct caggggaaca tggcgtacca ttgatgggat ggatctctta
     1681 ttccgtcagc gaaaaatcag ctatttattg acaacttggc aaggaaaaaa caccgcagtc
     1741 atcgaatctg cacaagcatt ggggttagat ctacttgata aaccaacgga tcaaactatc
     1801 cgacttgctt ccagttatgc cttaggagaa cttattaaag atgcactgct tcaagaagta
     1861 gaacaaatta ttgtcacttt aggaggaagc gggtgtagcg atggtggtct aggattactc
     1921 caatccttgg gtgcttcttt agaagggtac acagaaggaa atcctttatt atctactaaa
     1981 aaacttcatt ttgatcgaag aaacgttctt gtttctaaag taaaattgat tatcgctgca
     2041 gatgttacca atccatatac aggtcaacaa ggagctgctt ggcaatttgg aagacaaaaa
     2101 ggaggaatag atacgacgct agctttctta gataaacaag caggaaagat tgctcagcaa
     2161 ataaaagatt tctgggaggt ggatttagat gatattccag gaagtggagc agcaggcggt
     2221 attggtggag cccttttttt gttgggagcg aagatggttt ctggtttcga tttagtcagc
     2281 caaatcactg gattggaaaa aaagatcgaa caagcagatg tcatcattac aggagaaggg
     2341 cggatcgatc agcaaacgat ccacggaaaa gttccatacg gtgtagcagt gcttgcaaaa
     2401 aaatatcgaa aaccaataat cgctatttgc ggaagtagag accaagagct agaaggactt
     2461 tctgattttc tcccaattgt cttaagtatt catttgggtc caataggttt agaagaagca
     2521 atggaacaca ggcaaacatt agaaaaaaca aaaatcttag gacagacact tagcagattt
     2581 ttcaccatcc tcccgaagta gttgacaaaa tcattttctt tatgctatcg taatttcaaa
     2641 tataggacaa agtgagggat ccgtgcattg aaaaattaag tcgattgatg aaagctgcat
     2701 tcagactgta ccttgtggag acaaggaagc agtgtgcaga ttttcgggat tggcttggtt
     2761 ttttcgatgt atgggtcttt ttgtgtgtat ccaacccttg catcctcttt agccagttct
     2821 gaaaatagga ctggtctttt tttacgaggt gatggaaaat gtctaaaatc gaaataaaaa
     2881 atctgacatt cggctacgac agccaaggca cattattatt tgaacaagca aatctaaatt
     2941 ttgacacaca atggaaacta ggacttatcg gacgaaacgg tcgaggaaag acaactttac
     3001 tgaatattct acaaaacaaa ctaccttatc aagggcaagt aatccatcag caagaatttg
     3061 cctatttccc gcaacagaca aaagataaag aacgtttaac ctattacgtg ttaaatgata
     3121 ttacggattt tgagatatgg gaaatcgaaa gagagctcca attgatgcaa acagatcctg
     3181 aaatcttatg gagagaattc agcacactat cggggggaga gaagacaaaa gtcctactgg
     3241 cacttttatt tgtggatgac actcatttcc cgttaatcga tgaaccaacg aatcatttgg
     3301 atatctctgg tagaaaacaa gtagcggctt atttgaaaaa gaaaaaacaa ggcttcatcg
     3361 tggtcagcca tgaccgggga tttatcgatg aagtagtgga ccatgtttta gcaatcgaaa
     3421 aaagtcaact ggaactttat caagggaatt tctctatcta tgaagaacag aaaaaacttc
     3481 gtgatgaatt tgaaatggct caaaatgaaa aattgaaaaa agaagtcagt aggctaaaga
     3541 aaacagcagc tgaaaaagcc gaatggtctc gttcccgaga aggagataaa acaaagaaac
     3601 aagtcggatt catcgatact gaatctagac gagtgaataa aggagcagtg ggtgctgatg
     3661 ctgcacggac gatgaaacga tccaaagcaa tcgtgaatcg gatggagacc cagatcagcg
     3721 agaaagaaaa actattaaaa gatatcgaat atatcgattc tttgacgatg aatagccaag
     3781 cgtctcacca taagcgactt ttaagcgtag aagatcttca attagggtat gaaaatctgt
     3841 tattcgagcc aattcatttt acaatcgagc ctcatcagcg ggtggcgatt tcaggtccta
     3901 acggtgcagg aaagtcatcc attatccatt atcttctggg ggcattcaac ggcaaggtta
     3961 taggagaaaa ataccagcca aaacatctga gcattagtta tgcaagccaa aattatgaag
     4021 acaatcgagg aacgttggcg gaatttgcag agaaaaacca agtagactac caagcatttt
     4081 tgaacaacct ccgaaagctt gggatggaaa gagatgtttt tcataacaag atcgagcaga
     4141 tgagtatggg ccaacggaaa aaagtggaat tggctaaatc tttatcacag ccagctgaac
     4201 tatatacatg ggatgaacca ttgaattatt tggatgtctt caatcaagaa caattagaac
     4261 aactgatctt gaacgtgaaa cctgccatgt tactagtgga acatgatcaa accttcctgg
     4321 ataaagtatc tactgagatt atttctcttg agagaatcta acccttgtaa tctcaagaac
     4381 aacaaggtat ggttaagggg aactttgcca acgaaggaga gaatcacatg ctttatgtaa
     4441 cgagacacgg agaaacaact tggaacgcac aaggattagt ttgcggacgg gcagatgtgc
     4501 cgctgactga aaaaggacag atgcaggcac agaaactagc agaaaaggta gtagatttgc
     4561 ctgttccaat cacgaaaatc atccattccc ctcttcaacg agcaagagat acagcacaag
     4621 cagttgctga tcgtctcagc ttgccgctga ccgttgatga acgattggta gaaatggatt
     4681 ttggggatta tgatggactg ccaagcaaag atgagaactt tcaaaaagca cgtttagcgt
     4741 tcgctgtacg attcccaaat ggggagtcag tcttagatgt gtatgcacgg atcgttcctt
     4801 tattgaaaga atgcatcgaa gacgaagaaa atgtctatct gttagtttgc cataatgcct
     4861 tgataagagt gatcaatgct tattttcatc cgatgcctaa tgaggggttc tttacattca
     4921 tggtagataa tacagaattg gtttcttatg agtaattatg tttttgtgtt atttaaataa
     4981 aatatttcaa ggcactgctt ttgcttagca gtgccttttt taggttatga caattctttt
     5041 gataatataa actcaacctt tagaaatgaa atttaattat tttaataaaa gtattgaaat
     5101 tttgtttctt tagatatata ctctagtcat agaaatgaag acggatacag aaaaagaggg
     5161 ataatatgtt tggcttttca atatttatga acgattcttt gtcagaagag aagaaacagt
     5221 atatccgcca aatggcatcc aatggctttg tcggtatttt cacttccatg catataccag
     5281 aagatgatgt ttcggcatat caaaagcgat tgatcgaact aggaagcgaa gcgaaaaaga
     5341 ataaactaga attgatggtc gatatttcag gagaggcatt ggaacgagcg ggtttttcat
     5401 tagaagatct aacgcctttg aaagcaattg gtgtaacagg tttaagaatg gattatcata
     5461 tttccaatca gcagattgcc gactggtcac atcaattgaa aatcagtttg aatgctagca
     5521 cgatcacgcc taaagatatc gatgaattga aagaagcaga agctgatttc tcacagattg
     5581 aagcttggca taattattat ccacgtcccg aaacagggct ggacaaagaa tggtatcaga
     5641 aaaaaaatca atggctcaaa attcaaggtc tccttgtcca aggttttgta ccaggagata
     5701 cagagttgag aggcccacta tatcaaggat tgccaacttt ggaagaacat cgagggatcc
     5761 atcctcttgc aggcgctcta gatctattag caagtaacac ggatattgtt tacatcggag
     5821 atgcaggtct gtcagaaaac gttcaggagc aatttgcttc tttccaaaaa gaacagacag
     5881 tcttgctcca tacggaacct gtagatgaag aattttacga atatatatta gggaagcata
     5941 cgaatcggca agacgatgca agagatgtca tacgaagcgt agatgcacgt tttcgagaga
     6001 ttccgcctat cccagcaaga aatacagcta cgcgtatgaa agggtctatt actttagata
     6061 acgaaaagta tttgcgctat atgggtgaga tccaattaac caaatatgat ttgccagcgg
     6121 atgaaaaagt gaatgtagta gctaaagtta tcaaagaaga gctaccattg atcaaccaaa
     6181 tcaaagctgg tatgaactat caatttataa gaaaagaagg aagataaaaa tgagcaaaat
     6241 caatttagag aacctaacaa cggaacgcag aaaccaagaa acttttggat tagatgagat
     6301 gagtatttct caagccgttc aactaatgaa caaagaagat cagaaagtgg ccgctgcggt
     6361 tgaaaaagaa ctgacaagta tcgaaccagt gattgctaac acgattgagt cctttaaaaa
     6421 aggtggacgt ctgatttata tgggagccgg aacaagtgga agactaggtg tgttagatgc
     6481 tgctgaatgc gtaccgacat tcggtgtaga accggaaatg gtcataggtc taattgctgg
     6541 tggagaagaa gcaatgactg tagctgtcga aggggccgaa gattcttatg agctagggca
     6601 agaagatcta atcaagctga atttgacaaa aaatgatata gttattggta tcgcagctag
     6661 cggtcgtaca ccatatgtga tcggtggatt agattacgca aaatcgatcg gtgctgtcac
     6721 aggaacgatt tcttgcaata aacaagccga aatcagtaaa cacgcggatt tcccaatcga
     6781 agtcgatgca ggtccagaat ttttgacagg ctctactcga ttgaagtcag gaacagcaca
     6841 aaaacttatc ttgaatatga tttctactat cagtatgatt ggtataggta aagtattcaa
     6901 taacttgatg gtcgatgtca aaccaacaaa tgaaaaacta atcgaacgct caaaacgaat
     6961 catcatgcaa gcgacagaag ctgattacga aacagctgaa aagtactttg aagaagcaga
     7021 tcaaaatgtt aagctggcta tcgtcatgat tttgacaaat agtgataaag aggaagctca
     7081 agcaaaatta gctgaagcaa acggatttgt aaaagggacc ttatgagggg gaaaagacca
     7141 tggcaaaaaa cgaactgact ttggaagaac tggcaaaaca aatttataaa ggggcaggcg
     7201 gcatgggcaa tgtagaaagc attgtccact gcatgactcg tgtgcgtatg aagatcatca
     7261 atgatgatct tgtaaatgtc tctgaattaa aagcgattcc aggagtgctt ggtgtagtag
     7321 aagatgaaca gcttcaagtc atcatcggac ctgggaaagt gaacaaagta gcacagcaaa
     7381 tggttgattt ggcaggcgtg aaattaggag aaaaactttc ttctgtaagt acagctacag
     7441 caaattcatc agcatctgga aaagaccgtg taaacgaacg ggcacaagaa atgaaagcgg
     7501 cacaaaaatc gaaacaaaaa ccatctaaaa tcaaatcggt attaaaagac atttctaata
     7561 tctttgtgcc aatgattcct gcatttgtcg gtactgggat cgtggcaggg attgccgcag
     7621 ttttagcaaa cttagtcaca gccggaacac ttgatgcagc aacatggcaa caatatatcg
     7681 atgtgatgaa catcttgaaa aacgggatgt ttagctacct agttatctat acaggtatca
     7741 atgctgcaca agtttttggt gcaacaccaa ctcttggtgg agttatcggg gccgttgtga
     7801 tgctgacagg gatgaatccg gaagcaccac tgaaaaactt atttactggt gaagctcttg
     7861 cagctggaca aggtgggatc ctaggtgtca tcttcgctgt ttggctattg tcaatcgttg
     7921 agaaaaaact gcataaagta gtacctgatg cggtagatat catcgttaca ccaactcttt
     7981 cattgattgc catcggtctg attgaaattt tcttcatcat gcctttagca ggtttcattt
     8041 ctgatggcat ggtcggtggg atcaactggg tacttggcgt tggtggagca tttgccggct
     8101 tcgttctagg cacattattc ttgccgatgg ttatgttcgg actgcatcaa attttgactc
     8161 caatccatgt gcaaatgatt gatgaaactg gtcgtacgct attgcttcca attcttgcga
     8221 tggctggtgc aggacaagtg ggtgcagcat tggcattatg gattcgctgc aaaaaagata
     8281 aagaattaac agaaatgatc aaaggagctt taccagtcgg gatcctagga atcggcgaac
     8341 cattgattta cggagtaaca ttacctctag gacgcccatt tattactgct tgtatcggtg
     8401 gaggtatcgg cggggcagtg atcggaatga tcggaaatgt cggggctatc gctattggac
     8461 cttcaggagc cgctttgatc ccattgatct ctgacggtaa atggttaggc tacatccttg
     8521 gattattggc agcttatgct ggtggcttcg ttgctacatt cttcttcggt attcctaaag
     8581 accgtttaga aaaagaagaa ttagcgactg aaacagccac agtaaatgaa gtgcctgaaa
     8641 aagtagtacc tcaaacttca gctgaaagtg tgactatcct ctcatcagtt gctgacggaa
     8701 cagttgtttc tttagataaa gcaagtgatc cagtttttgc acaaaagatg atgggtgaag
     8761 gctactttgt agaaccagaa aacggacata tctattctcc agttactggg gtagtcagct
     8821 ctgtcttccc aacgaaacac gctattggga tcacaacgcc aaatggttta gaaatcttgc
     8881 ttcatatggg aatcaacaca gttgacttag gcggtacgcc atttgatgtg aaagtaacag
     8941 aagggcagca agtgacacct gatacgcttg tagcagaagc tgacttagaa gcgatcaaag
     9001 cagcaggcaa agaaacatcc atgatcgtct tggtaaccaa tatggatcgt gtaaaaaact
     9061 ttgtcttgga aaaaacaggt aaagcaaaag caaaagcacc tgtgatggat gtcaaagctt
     9121 aatatgatag aaacaataga aacgaaagaa gaaactgaaa tctatttttc agcttcttct
     9181 tttttattat ttattgtttt ctgctaaaat ctgataaatt cgtgtcacat cagatggtgt
     9241 tccccgtaat tcataatctg ccaagaaagg aaagccaaat gtttgtgcat attgtttggc
     9301 tgttagacaa tactgattat tgaagttttt atttccgcta ccgactacac caagacaaag
     9361 tttatgattg tcttcatgtt ccagatattc acgcatcgtt tcggtcaaga tttctgtatc
     9421 accgttatct aaaccatttc cgccgtctaa ataagtagga acgaaagtaa aaaatggttc
     9481 tgtttctttc gtaaaatcac tattttcatg gatttctttt aaagtaactt caggattgac
     9541 aggatcttct gcatgcattt tttcagcata ttctgctaga tgtttggcaa aggcacgcgt
     9601 atttcctgaa atcgatatat ataaaatgtt catggatcat cctccaattc tttcctttta
     9661 gtatagcatc ttttttaagt tttttggtgg tgtaatttgg aaagggacta ggcgctttgc
     9721 ttgtataatg agaaaaaagc cggtagaatt atatttctat taaagttttt attaattaag
     9781 taaaaataaa aaaggtttgt tatacttttt gataaaagcg gttttatttt ggaggatgct
     9841 tacatggata cagagcaaca gaaaaaagga attggtttaa ttccacttgc tgccttagta
     9901 attggttcag cgattggagg tggcgtattt ggtattatga cggacatctc cggatcggct
     9961 ggcggcccag ctattttcag ttgggtactc gtaggaacag caatgttgat gctctccttg
    10021 tcgatcaata atatcaataa aaaacgtcca gatttaaaag gcgggatctt tagttacgca
    10081 gaagaaggtt ttggccgttt cgctggtttt atcagcggtt ggggttactg gctcacatgc
    10141 tggttaggca acgtagcttt tgcaacattg ttgatgagcg cattaggata tttcttccca
    10201 gtatttgaag gtgggcaaaa tctggcatcg atcgtgatga gtacagtctt tttatgggga
    10261 tatgcatggc tagtgaatcg gggagtcgaa aatgctagtt tcgtcaatgc tatcgtcaca
    10321 ttctgtaaat tagtgccatt atttttattt attgtagtag ctatcagcac gttttcgatc
    10381 caacaattca ttgataactt ttctagcgac attatattga atgcgaatgg acagccgatc
    10441 ccgttttcca gtcaagtatt gagttgcatc atggtgatgc tttgggtatt tgttggtatt
    10501 gaaggagcct ctgtcgtagg ttcacgagca aaaaaacaat cagatgttgg gaaagcaacg
    10561 attctaggga tattcggctt gattattatt tacgtcttgg tttccatgct tccatatggg
    10621 acaatgacga tgaatcagct gcaaacgatc aaggcgcagc ctgctatggg ctatgtgttt
    10681 gaaatgatgg ttggtaaatg gggagcagtc gtgatcaacg gcggtttgat catttcttta
    10741 gttggtgttt ggctctcatg gacgatctta ccgattgaaa caatgggaaa catggctgaa
    10801 gacggacttt tgcctaaagc atggggaaaa ctcaacaaaa atggggcacc aacttatgct
    10861 atcgtattga cgacgttatg tacgaatgtc tttttacttt cattattatt cactgacagt
    10921 gcttataact ttgcttacac acttggtaca gcagctattt tcttcacgtg gcttttctta
    10981 ggattgtacc aaatgaaact ttcttatcag cggaaagaat gggtccaatt tttagtaggg
    11041 cttttagcaa gtgcctttca agtatgggct atgctagtcg tagcctttaa tgaagtaatg
    11101 cttgttcttg ttcttttctt gccaggcatt tatttttacc tcaaagcacg taaggagcaa
    11161 aacgagcctg tacaacatat ccacttagat aagattttac ttataggtgt gacgatggtc
    11221 ggagtgattg caatggtttt atttgccact gggatgcttc acgtatagaa gtataaaaga
    11281 agtataaaga gaggttgtga gcctgtcgtt tattcaaaaa catactagga aaggagctgt
    11341 gacacaaatg ttgtcacagc tcctttttca gaataaacgg tgtttaagag acagccaatc
    11401 ggcaataagg ctgaacgtct ctttcacagc ctcttttttg atgagtcatc atacattttt
    11461 tcgcttaaat acgagatatc ctaatgctaa gaacaaaacg atgtaagcta aattaccgaa
    11521 tagcatttga ttagtagaaa gatgagtcaa ttgcttcatg atctcttcgt ttccaatttg
    11581 gttttgcaga ttcaacatac tgatcggatt ccatttgatc cactcccatt tttggatgag
    11641 tgcaataagg ataccagata tgattgacga agcaaaataa aagacgattc ctgctgagat
    11701 ggatgcgccg gaactattga taaagcaagc aatcatcaac actaaactta aaatcagcca
    11761 taaaccgata taactaccca aagtataagt gaacaagctt tggatcagtg tttgaccagt
    11821 agaaaccttc tccgtgaagg aaatcgaagg gaaaagaatc agtttcatca acacagtgac
    11881 aataatagct aaaaggtata aataaacaga ataaataact aatgtgatcc atttgcttac
    11941 taatatttct cctcgagaat actttcgata aaggagattt ttcaatgtac catattgtgc
    12001 ttccatcgaa atgatcgtgc ttgcagctgc aatcatgata aagacaatcc aagatgtggc
    12061 actaaaaagc tgagcagtca tttcaactgg atcaatgatc gtcgtgtatt ttttggctag
    12121 aagtgctgtt cctatgagca aaacaactaa tagaacagat aaaacagcag ttgacttttt
    12181 cttgatcaat ttaaataatt cttgttttac aagcaatgtc atttttcttc ttcccccttt
    12241 actgaatcca gaatttccaa tagagaagat tccaaatcat tcgtcagatg ctggacgtct
    12301 gtcacatgga tattttgtgc agacaatagc tggatcacgg ttcctaataa ttcttcgttt
    12361 tcttttaaaa gcttgatttt atcaggatct tccaaagtat atccagcttc tgtcaagatc
    12421 gttcgagcag ctagatcatt tgttgtagag ataacgatga aatcttgcgc tgtttggttc
    12481 aattcagcca ttgtacattg tttgatgatc tttccttgat tgatcaggat cagctcatcg
    12541 accatttttt caagctcgct gagtaagtga ctggagatca agaaagaggt gccctgagta
    12601 gccaagtcgg taatgatttt tcgcacatct cttgttgctt gtggatccaa accgttcatc
    12661 ggctcatcta aaataacgat agacggatgg ttcagtaagg caagagcaat tcccaatttt
    12721 tgtttcattc ccaacgagta ggatttcgct tttttgtgaa tgtacttttc catcttgagc
    12781 tgattcacga tagtgtcgat agcagataca tcgttggttt cagagaataa cttcagatga
    12841 tcatagcctg ttaagaatgg atagataccc gggtattcga tcaatgctcc tacttgttcc
    12901 aaccctttat gactagaggg agaaatctca ttttcaccaa tacagattgt tccatctgag
    12961 taatggatca gtcctaaaat agctttcatg atcgttgttt ttccagcgcc attaggacct
    13021 actaatccaa cgattttgcc aggggataag ctaaaactga catcgctgag ggcttgtttg
    13081 tgaccaaagt tcttggataa ttcttggacc gaaagacttt tcaaaaatat tcactccttt
    13141 tctatagata gtacaagcat acacctgatg agtggagaag tcgctaggtc attggactta
    13201 tttcttattt tttcataaaa aaattgaata ttaaataaaa aggcttattt tttctgatca
    13261 gtacttattc caagtgtcta gtggccgcta gtaatcttga tgccaatgat actgatgagt
    13321 agcatcccca caaagaacca agtggaaaga ttcagcttat catgaaacaa gaccacacca
    13381 attatgaccg aaccaactgc gccaatccct gtccagatag gataagagag actcatcggc
    13441 aaacttttga ttgcctttga caaaaagtaa aaactagcaa tcatgccaat cactgtgtaa
    13501 aaagaataat tgattttaga aaaaccatca ctccatttca tcatcgttga ccagaatact
    13561 tccaaaattc ctgctatgat taattccatc catgccatac ttacattcct ccttaactat
    13621 aaaaaaatac acaaaaagag gaaaatcatc ccttcaaaga cctaatggaa tgatcatcct
    13681 ctttatccta cccggtggca gattgtatat ctttttctgt agtatagcac acctatccag
    13741 atatcggcaa tctcatactt tttagtaaag tgtaccaagc actgacggat atatcgttag
    13801 cggaaaagaa gatgaatgct ttgcaatttc atagaaagaa gttgttattt attaatcatt
    13861 taaaaaaaac agtaactaga ccttatttct atatattatc gggcaataaa ttaaaaaaag
    13921 ctttacctta caataagtaa gataattttt gtgataaaaa aataacgaaa aatatttaaa
    13981 aatagtgtct atttcgtgag aaaacaacta tattttttat gtgttttgct ttataattaa
    14041 aaaaatattg tcattttatg gaggaaaata tatggaaaat tatcttagcc ttttaggcgt
    14101 cttgattgtt attctcgggt ttgcatttaa attagactcg atattgatcg taatggttgc
    14161 tttagttgtt acagctttga ctggcggtct tggcattcaa ggaatgttag aacttttagg
    14221 tacaagtttt gtaaacaatc gcgggatggc gatttttatc atcattatgt tggcaacagg
    14281 aacgcttgaa agaaatggtc tgaaagaatc agcggcttcc ttgatcaagc gattcaagaa
    14341 agtatctgct ggtatgattg tagatattta tgggatcttt cgaatgatct ttgcggcttt
    14401 taacgtgagt tttggtggag ttgctggatt tgttcgtcca atcattttac cgatggcatt
    14461 ggggaccatc gaatcaaaag ggttagaagt ccatcctaag catgaagaag aactaaaagg
    14521 tatggcttca gctatggaaa atgtctgctg gttctttggc caagtactat tcatcggagg
    14581 agcaggggcg ttgctagtcc aatcaacact gaaagatcta ggatatgacg taacattggg
    14641 acagcttgct ttagtggaag ttccagtggc tatcacggct ttagttgtgg caagtgtcta
    14701 cttctatctt aaagaaaaga aattagcgaa gaaatattat ccaggaaagg ggcaataaga
    14761 tggacttttt tacaaatcct gatattttat taggcgataa attactggag atcctttata
    14821 tcgtgatggg actcgtattg atttacactg gagtaagaaa tttaacagat aaaaccaatc
    14881 ctcatcgtta tgggtcagcc tttttctgga cggtcttagg ggtagttatt gcaggaggaa
    14941 gatggcttcc ggcaatcgtg aacggtggct tgatctttgc gatgaccata ccagcaattg
    15001 ctaagaaagt cagcaaagga gaaagccggc ttccatcaaa agaatatatg gaaaaaatgt
    15061 cagacaaact aggaatgaaa atttttattc cagctttgag tatcggtgtc tttgcgatct
    15121 tgtttgctct atttaccaat ttaggtgctt tagtcggcgt gggcgtcggt gtttttgcag
    15181 ccatgctaat cttgatgttc ttttctcgag ataatcgacc aagtacattt ttagatgatg
    15241 cagcagatat gctgggcaca gtagggccgt taagcatgtt gccaatgctt ttagcttctc
    15301 taggtgcggt atttacaagc gctggagttg ggacagtgat ttccaatgca gtaggtacga
    15361 tcgttccaga aggaaatgtg aacatcggca tcatcattta cgctcttggc atggtgatat
    15421 ttacggtaat catggggaat gcatttgcgg ccatcaccgt gatgacggtt gggatcggtg
    15481 caccattcgt atttagtcat ggagcgaatc cagcgttaat aggaatggtt gcattgactt
    15541 gcggtttttg tgggaccctg ctgacaccga tggctgctaa cttcaatatc gtgcctgtag
    15601 cgatgctgga gatgaaagac aaatacggag tgatcaaaaa ccagttgttt attgcgttat
    15661 ttatgctagt tttccaaatt gcttatatga ttctatttaa ataatagaag agaggggttg
    15721 tgacagaata attgtcgcaa cctcttctaa cattgtagtg gaacactatt tttttataag
    15781 aatatattaa gtttgatctg ttatgttatt taaactattg tttcctttat ttacgctgtt
    15841 caaggaaaat ggtatgataa aagataacca tatgttaaat caatcggacg gaggaacaac
    15901 agatgaaagt actagtaaca ggttttgatc catttggtgg ggacaaagtg aatccagcct
    15961 atgaagcagt aaaaaaaatg ccagatgaaa tcagcggtgc tgaaatcatc aaagtggaag
    16021 taccgaccgt attcgaaaaa agcagtcaag tagtcaaaga agccatccaa cagcaccaac
    16081 cagatgtcgt gatctgtgtc ggacaagcag gtgggcggtc agcagtctcg ttcgaacgtg
    16141 tcgcaatcaa tctagcagaa gcaagaatcc ctgataatga aggaaatcag ccattcgata
    16201 cggctttaga agaaaacggt ccagccgctt actttacctc attgccaatc aaagcaatga
    16261 caaaaaatgt acaagatcat ggtctaccag cgtacatctc ttatacagca ggaacatttg
    16321 tctgcaatga tatcatgtat cgtttgcttc atttgatcga aacacaattc ccggcaattc
    16381 gaggtgggtt catccacgtg ccattctcac ccgatcaagt gatcgatcgt ccagtgggta
    16441 cgccttctat gtctttagaa gacattgctt cttctttgac ttatgcagtt gaagcagcag
    16501 tagaaaataa agaagatatt tccggaaatg ccggaacaac tcactaattt agcaagaaac
    16561 actggctggt tgctaacgtt atgttagtag ccagcttttt gtaattagaa aggaaagaaa
    16621 cagccgtgga agaatggcaa tccgtctttg aagaatggtt tccaaaagaa atcagcaaaa
    16681 gctatcccat caaaatttct aaacaataca caagcagtca acgttgggag atctatgcaa
    16741 aattaacgaa aaaacagcgg gaactagtcg ataagcaccg ccgatatcta atcagctctc
    16801 gttttatgga agaacattat ttagctgcaa cagattgggt gttttctgac ttcaagatca
    16861 atccgttttt tcgaacaaaa cgaagccagc aaaaattgta ttgtgagtgt ggtagagaat
    16921 taaaagtgca atacatcgtt aaatcgccaa aaaccggaaa gatcctaaaa ctaggcatca
    16981 accactttgc cgatcacctg catgtctctc cgacagtggc agcttcgatc catcagggaa
    17041 tgacaaaagt tgatctggcc ttagacgaat tattatggct taagcagaag aatatcgatt
    17101 ttcctgaagg actatggcaa aaatactgtt ttgtcttgta ccaaaatcgt cggatgaaac
    17161 agccatattt accggatata aaattagctc agcggctcgc agaatttcgc caagtagaaa
    17221 tgccgattta catagcggat tatcaagcat tggaaaatga aatcaagaaa ataagtgaac
    17281 acatcaatgg gcagtcaaaa aagcgacaga taaaaaaaga actatttgac gactttgcag
    17341 aagaattagt aaaggatgta gaagaattct tgatcaacta tcgcgcattt ttacgtaaag
    17401 attggcaatc catcgtatat gaagaagtgc cagtacatcc taatgcttat tttgaaacat
    17461 ttatttccgt gttgagaaag acaaaacgtc aacgaacacc agaagtcact gctcagatgg
    17521 aatattttgc gaaaaaccaa cgattcatcc aaccaaaaat ctatctattt atttggaagc
    17581 aatattgtcg ctatggtttt acagaagggt tcttcgacag cattcctcgg atagtcagaa
    17641 atggtttttt aaaagtattg cgtaaagaac gagaagctat acaatctgct gataagaaag
    17701 accgtacagt ctcaaaagaa aaatggcaac tagtagtgaa agatatccaa tctggaaatg
    17761 tgcaagagac aatcgacaaa tggaaaggaa aacattatcg ttttactgaa gctcagaaac
    17821 aagcgttgga atattatcag aagttagaag aatcactgcg tttcaatgat gaggcaagaa
    17881 agtatctgaa ggaattacta taaaaaacat actaagatta gaggggaaca tcattgacga
    17941 atgatgttct cctctatttt ctatt
//
LOCUS       DADQDV010000274        14390 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.guided.074, whole genome shotgun sequence.
ACCESSION   DADQDV010000274 DADQDV010000000
VERSION     DADQDV010000274.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14390)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14390)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14390
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.guided.074"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(<1..156)
                     /locus_tag="J8S10_003255"
     CDS             complement(<1..156)
                     /locus_tag="J8S10_003255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HAZ9631749.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKS"
     gene            279..1130
                     /locus_tag="J8S10_003256"
     CDS             279..1130
                     /locus_tag="J8S10_003256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAZ9631750.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            complement(1381..3339)
                     /locus_tag="J8S10_003257"
     CDS             complement(1381..3339)
                     /locus_tag="J8S10_003257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAZ9631751.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(3336..4208)
                     /locus_tag="J8S10_003258"
     CDS             complement(3336..4208)
                     /locus_tag="J8S10_003258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAZ9631752.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            complement(4550..5422)
                     /locus_tag="J8S10_003259"
     CDS             complement(4550..5422)
                     /locus_tag="J8S10_003259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAZ9631753.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            5550..6119
                     /locus_tag="J8S10_003260"
     CDS             5550..6119
                     /locus_tag="J8S10_003260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HAZ9631754.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLLVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            6186..6923
                     /locus_tag="J8S10_003261"
     CDS             6186..6923
                     /locus_tag="J8S10_003261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAZ9631755.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            7154..8422
                     /locus_tag="J8S10_003262"
     CDS             7154..8422
                     /locus_tag="J8S10_003262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosaminidase"
                     /protein_id="HAZ9631756.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            8909..9373
                     /locus_tag="J8S10_003263"
     CDS             8909..9373
                     /locus_tag="J8S10_003263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAZ9631757.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            9357..9986
                     /locus_tag="J8S10_003264"
     CDS             9357..9986
                     /locus_tag="J8S10_003264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAZ9631758.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVTRDHGYETNPI
                     GGVEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            10340..11818
                     /gene="msr"
                     /locus_tag="J8S10_003265"
     CDS             10340..11818
                     /gene="msr"
                     /locus_tag="J8S10_003265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Msr family ABC-F type ribosomal protection
                     protein"
                     /protein_id="HAZ9631759.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            11865..12311
                     /locus_tag="J8S10_003266"
     CDS             11865..12311
                     /locus_tag="J8S10_003266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HAZ9631760.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(12510..13025)
                     /locus_tag="J8S10_003267"
     CDS             complement(12510..13025)
                     /locus_tag="J8S10_003267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAZ9631761.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            13142..14344
                     /locus_tag="J8S10_003268"
     CDS             13142..14344
                     /locus_tag="J8S10_003268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAZ9631762.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
BASE COUNT         4515 a         2600 c         2960 g         4315 t
ORIGIN      
        1 ggattttttg agctgactca tgattttacg tacatttgct gcatttgttt cgatactact
       61 ggcaatcatc tcactagaaa gtgatcgggt atcttgaaac atttcaatat aggcaagtac
      121 atggattgca tcactaaatt gcagagaata cttcatcagt tgtcatcctt tcattttttt
      181 tgcttgactt atcttaccac actctttatg ataaaggtgt aatttataaa tgtacagctg
      241 taaatcttaa caaataaaaa gaatagggag tggcaaatat gcattattta gtaacaggag
      301 caactggagg ttttggtggt tatgcgctgg aattcttaaa aaagatggtt ccacaaaatg
      361 aaatctatgt actagtacgt agtgaagaaa aaggagaagc actgaaagaa gctggattta
      421 atatacgtat tggtgattat gatgatttag actcaatgaa agaagcgttg aaaggaatag
      481 atcgattgct ttttgtctct ggcgttccag gaaatcgtca agccgaacat aagaatgtag
      541 tgaaggcagc acaagcagct ggggtatctt atatcgctta tacaagtttt gcagatgccg
      601 atcactcgat cagtgtatta gcgccagatc accaattcac tgaaaaaatg attaaggatt
      661 caggtatttc ccatacattt ttacggaata attggtatgt agagaatgaa ttacctatca
      721 ttgggcaggc tttaaaaact ggtcaattcg tttatgctgc aggaaatgga aaaacaggtt
      781 gggcattgaa acgtgaatat gcagaagctg cagcaaaagt actagtagaa agtgactctc
      841 cagaaatctt agaattatcc ggcaatctaa ctgactatga agaattagcc aaggcattag
      901 agcgtgcgac aggtaaagag ttagaaatta ttgaagcaag tgatgcagcg tttgtcgaaa
      961 atctaaaaga agccggattc cctcaagaag cagctgacat gtttttagcg atccaacatg
     1021 atattaaaaa ggatcagtta gctatttcct ctgatgattt agaaaaagta ttgggaaaac
     1081 cattaacttc tcttgaagca gcattaaaag aaatattgga tcaggaataa tgtataaaga
     1141 ggttgtgaaa aagccgatta gttttgagta tgaagaaaaa ttttgtgaaa aagctgttct
     1201 gcatcaagta ataagaagag tcaaataaaa aatagctctt catatgtttc gtttagctgg
     1261 acttattacc gcggagttgg caggagaacg ccgtttttat tcggaaaaag gagctgagac
     1321 aagatttttg tctcagctcc tgtttgttta tcgataaaaa agtctgggga agacgatggc
     1381 tcaggctttg ttggaaacag agccgatttt atcatttgct tttacatcac gtgcgggttc
     1441 gatttctaag ctttggactt tgtcgccatt tgtgaataca acgaccatat ccgtgttttt
     1501 gcctgcagat tgaatagcgg caagatcaac taaagcaatc aattgacctc ttgcgacttt
     1561 ttgaccttct tctacatata aagtgaatgg ttcgcctttt aagtcaacag tgttgatgcc
     1621 catatgaagc aagacttcga taccagcatc tgtttggatt ccgacagcat gtttcgttgg
     1681 gaaaatgttt gtgatcgtac cagcgattgg agagaagatt tctccatttt ctggtaatac
     1741 agcatagccg tcacccatca ttttttccgc gaatacatca tctgaaactt cagtgattgg
     1801 aatcagtttc ccatttgcga tagcgtaaat atcttgttcg atcgtttcac cggcaaatgt
     1861 ttctgtttta accacggtgt ttgtttgtgc aggtcgtgct gcagcaccac catgtagttt
     1921 tgccatctca tctgcaacga attgtacttc tgtacctacg atgacttgcg cattttttcc
     1981 gtcgatgatc ttcataccag gtacgccagt ggctttgatt ttattttgat cgatcaggcc
     2041 tgtatctttg acttgcaaac gaaggcgtgt agtacagtta tcgatcgaag ttacattgtc
     2101 ggctccgcct aatgcagcgt agattttgct tgcttgtgcc gcatatttat tgtctgaatt
     2161 agtcgttgca gtatcgtcat ctgaaagatc tgcttcctcg cggccaggag tcatcagatg
     2221 gaattttttg atagcaaagt taaagccaaa gtagtaaatc actgctgtta ctaatccttg
     2281 gacgatcaac atcaatggct gattcgcaat cggatttttc aaagatagga agtaatcgac
     2341 aaatccggca ctaaaggcaa atcctgctgt ccaatggaag aatgcactca ctgctaaaga
     2401 aatcccagtg aaaattgcat gcaagacata taatggccaa gcaacgaaca taaatgaaaa
     2461 ttcaagtggt tctgtcacac cagtaaagaa tgaagcaaaa gctgctgcta gcatcaagga
     2521 agctgttttt gctttgtttt ctggacgtgc atttctgtaa atagcatatg ctcctgctgg
     2581 aagcccgaac atcatgattg ggaaaaatcc agcttgatac attcctgtta cgccttttgt
     2641 tccttcagaa gccaaaaatt taccaatatc attgattcct gctacgtcaa accagaacac
     2701 ggagttcatt gcttgatgca atcctgtagg gatcagtaaa cggttgaaga agccataaag
     2761 acctgcacca ccccagccta aactcaaaat gaatttagca aaagaaacta aagcagagta
     2821 aaccggaggc catacgagca gtagcactgc actgatcagc aacatgacaa aggcagccaa
     2881 gattggcact agacgcttgc cgctaaagaa agataaagcc atcggtaatt ttgcttcgtg
     2941 gaaacgatta taaagagctg ccgcaatcaa tccggcaata ataccaataa atacgttact
     3001 gatctgagca aaagatggat caactgattc tggtttgata ttcaataaag tagctactga
     3061 atcagttttt aaaacattta ctggaacttc aaatgcgacc aaacctgcca aggcagcagc
     3121 acctgatttg tccactgaca tccctagtgc taacccaacg gcaaacagca aaggtaattg
     3181 acctaaaact gcgttaccgc cagcttgtaa aaaatgagcg acaatgtcgt tactataaga
     3241 tgcccaccag tttccgatcc ctactagtaa agcagcagca ggtaagaccg caactggaag
     3301 ttgaagggaa cgtcccattc gttgtagata tgctttcaat ttttttcctc ctcatgattg
     3361 ttaacatttg tttgtacgat tgcgcttctt aaacgctcga tatggatggc caagtaaccc
     3421 agttcttctt tcgtgatcgc gagctggtat tctttggtca gcaacacacg gattttttta
     3481 gaaatcttat agctttctgg gtattttcgt ttgaccattt ctacgatttc cgtgtctaaa
     3541 acagcatatt gttgcgcatg ggttcgttgt agaagcagtc gtaaatgatt caccagtctt
     3601 gaataattca gtgaaaatgg ttctgaatgg atatctgttt ccaattctga ttccactaaa
     3661 tggatgatgt cagatacaat cgtcacttca cggatactgc gatggttatt gttccgaccg
     3721 cttcgtccgc tgtgaatatg gattgcgata tatcctgctt cgtcataagt atatggaatc
     3781 ccaagctctt ttgtcagata ctctactgcc cattgagcaa tactgaattc atcactgtaa
     3841 agcacttcga tttctcttaa aagtttgttg cggatgacga taccgttatt aatgttctcc
     3901 gcagaaaaag caatgtggtc ggtcaaagcg atcaatacat gttcattcaa cttttccatc
     3961 aaaacagttt ccgcatgatc aatgatcgtt tctgctgcaa ataaaaagcg ttcatcaatc
     4021 tgattaagta aattttgcaa cttgatttga ccttctggtt ccatgacaaa tatccgttcg
     4081 acatcacgat caaaaatcaa atcatttctt tttctgtcaa atccaatccc ttttccaata
     4141 gctacttttt cctgtccacc gtcatctacc aatactgcat tttgattaaa gatctttttg
     4201 attttcatgc gcgcaccctt tttgaagatt tggttttcac gtttgctaga ccagttgatt
     4261 gcggccaaac aaaaatagac acgaaaaacc tcctagggaa accatgttcc tcagagattt
     4321 ttcatgccta gtatgatcta gtcacatgaa acgaattatt gttaacgtaa tcaattttat
     4381 atagacagtt atgttttgtc aattcttttt ttataattat agtaatttac tggaattatc
     4441 agaaataaaa ggaagaaata aattaagaaa cttatgttat ttaatcgttg gatcttttgc
     4501 ttatcttatt cgttgttaaa aagctgaaag cgaaggaaaa aaactctact taactgtatt
     4561 tctccgttag gacatctaaa aatttacgag cagcaggaga aagaggctgg tcttttttcc
     4621 aaatgagatt cagtgaagct tgtaatggcg gatcgagtgg gatgaatatt ttttccgtcc
     4681 cataagtatt gatgatccca tctagagcta atgcaccaaa agtcccgtta tcgaccatca
     4741 aagaagcatt gtacaataag ttatatgttc cgacgatcga taactgatct atgctgaaac
     4801 ctagccattc agctagttga ctgtccactg acgtttgccg ggaaatgatc aaaggaacag
     4861 ttttcagttc ctgcggatgg atgacggttt gctttgctaa aggatgattt cgatgtatca
     4921 aaagtcccca acgatcttgg gctggcagtc gaaatgactg gtatttttgt ttgtttgtcg
     4981 gttcgattac gagtccaaaa tcaagtaatc cgctatccag tttgtctatg atatcatctg
     5041 cattcccgct atataaatga aactggatat caggatgcgc cttgatcaac gaatgaaggc
     5101 tatcagaaat gaaagagatt gctttagttt cgcctccgcc aatgtagatt tctccagaga
     5161 tgattgcgtc atttgttaaa ttgttcgccg ttttttctac caacgacaag atttcttttc
     5221 cttttgaata aagatatcga ccagaatccg tcaactgtat ctctcgggag ccccgagtga
     5281 aaagtgtcac accaagttct tcttctaaat ctttcagttg ttttgagaga gtaggttgcg
     5341 tgatatgcag agattttgct gctcggctga tatttttttc tctagctact gctaaaaaat
     5401 acgtcagtat acgaatatcc attttttccc tcctgttttt aaaaaagcat accactaagt
     5461 atagttaaaa ggaatagtta agtatgtttt ataagtatta gacatgataa gccgtccgtt
     5521 ataaagtaag gataaaagga gggagcaaaa tgacaagcct catcgaaaaa caaatcgtca
     5581 ataaagagat tcgagtaacg gatccgctct ttgaagtgat ccatcagatc caagctgaaa
     5641 acgaagagcc tttagcagcg ctgaatactg ggtaccatga accagcagat atccgcaaac
     5701 ggctagaaaa tatcattagt gacaaagtag atgatacggt gactgttctg ctgccttttt
     5761 atacagattt cggcaaacat attagtatag ggaaaaatgt ctttatcaat cgtcaagtga
     5821 tgttcgttga cttaggtggc atctgtttag aagattcagt attgattggt cctcgtgtca
     5881 acctcatcac ggtgaaccat ctaaccgatc caaaagaacg aagaggcttg ttagtaaagc
     5941 caatccacat caagaaaaat gcttggatcg gagcaggagc aactattctg ccaggcgtaa
     6001 cgattggcga gaatgccatt gttgcagcga atgcaactgt tacgaaagat gtcccagaca
     6061 ataccatcgt tgcaggaatc cctgccaaaa tcgtcaaacc tgtcgaacgg attatttgaa
     6121 cagtaagatg aaataagaga tagtgagtat aagcaagaga tttttcaaaa caggaggaga
     6181 atagaatgaa tgatttatca gaaaaagtga ttgtcatcat gggcgcttca agcggaatcg
     6241 gtgaagcaac aacgaagcta ttagcagaaa aaggggctaa actagttata gctgcacgcc
     6301 gagaagatcg cctaaaagca ataaaagaat ctttaccaga agctgagcta tatattcaaa
     6361 cagcagatgt aagagatttt gcacaagtcc aagcagttat cgatttagcg atggaaaagt
     6421 tcggtcgaat cgatgtattg tacaataatg caggaatcat gccaaccgct ccattagttg
     6481 aaggtcaccg tgatgaatgg caaaatatgc ttgatatcaa catcatgggt gtgttaaatg
     6541 gaatttccgc cgtacttcca atcatggaaa aacaaaaatc tgggcatatc atttcaactg
     6601 attctgtggc gggacatgtt gtttatcctg attccgccgt ttattgcgga acaaaatttg
     6661 ctgtccgtgc aatcatggaa ggattacgtc aagagcaacg gcaaaataac atcaaatcta
     6721 cgatcatctc tccaggagct gttcaaactg aattatatca aaccatcagc gacaaaaagg
     6781 ctgctcttga acttcatgaa gcgcaaaaag aatggggatt gacctccgaa gatatagctt
     6841 ctgctgtagc atttgcgata gaaacgccag accggatgtc tgtcagtaac atgattatcc
     6901 gtccgacgac acaggaagta taatccataa cggataatat ccaaagagaa ttacttgtta
     6961 aatagttatt caaacgacca tcaatttaag gcgtgaatgg agaagaatat tcttcattta
     7021 cgtcttttta tgtagaaaaa gcaaatttat caaaaagaaa caaatgttat ttaaatatgg
     7081 acattgactt gcttttactt ttttagttac actgttattt aggaaaagtt tcataattca
     7141 aaggagaaaa aagatgaaag caaagaattt attatttagc gttattcttt taggaaatct
     7201 agcagttgcc aacacaacag tgctagctga agaatcgaca gaaactgtcg caactcagac
     7261 atcgagttct tcagaaacag gaattgaaaa cgatacagag agtactttgc agtcagctac
     7321 tgtctcagaa aatacaattt caaccgaaga accaacaact gaaacaacag aacaaacaca
     7381 aaccgaagac agtacatcag cagaagctca gaacaatcca gagaatgcag aagaaatcac
     7441 gaaccaattg acagatgggc aaacattgac acatacccat caagcagatt tgtctgaatt
     7501 cgaaaactat actggctatg ctttttatgc tcgctcatct gctaattctc aacaagcgtt
     7561 cattgatagt attgcctcaa ctgcacaaag tttggcaagt gccaatgact tatatgcatc
     7621 agtcatgatt gctcaagcca tcgttgaaag tggctggggg aacagtactt tggcttctgc
     7681 ccctaattac aatctatttg ggattaaagg aagctataat ggccaatctg ttacgatgcc
     7741 tacttcggaa tatgtgaatg ggcaatggat tacggtgaat gccgctttta gaaaatatcc
     7801 ttcgtacaaa gaatcattgc aagataacgt aacggtattg aagacgactt cttttcagcc
     7861 aggcgtttac tactattccg gtgcatggaa aagcaatacg aactcttaca aagatgctac
     7921 ggcttggcta acaggtcgtt atgccactgc gcctaattat ggttctacat tgaacaatgt
     7981 aatcgaaacc tataatctga cacagtatga tacagcacca acttcaactt ctccgatgta
     8041 tcgtctgtat aaccgtcata caggagaaca tttatataca ttgaatgccg gagaaaaaaa
     8101 ttatctgcca actgtaggct gggaatatga agggattgct tggcaagcac caaacagcgg
     8161 acaacctgtc taccgtttat acaatcctta cagtggagac catcattaca caatggcaca
     8221 atctgagatc aactctttaa caaaaatcgg ttggcgttat gaaggtctaa gtttttattc
     8281 tggtggttcc aagccaattt atcgactatt taatccaaat gaaaaaactg gtacccatca
     8341 ctataccttg agtgctaagg aaagagattg gctaacaccg atgggctgga gatatgaagg
     8401 aataggattt tatggttatt aaaaagaggt agtgaaaaag ctgccctgca tcaagtagta
     8461 agaacagcca aacaaaaaca gattttcatg ttttttgttt ggttgaactt attaccgcag
     8521 atgcaagttt ttgaacaccg tttactcaaa aaaggttgtg acaacatctt gtcataactt
     8581 ttttattact gtttaagcat actgatccaa tttctaatat tcgacgggat tcttgcaaaa
     8641 ggcgatttcg gaaatttttg gcggtgtaaa attttctact gcagaagagc tatcttctat
     8701 agtttgataa gaatcaataa tcttggtttt agcgttgtgc tttctttatc attttttccg
     8761 ttcattctac aaaaaatttc ttttctctat acttttctat tgagagcgtt ttttttatta
     8821 cacagctgat tctttgactt ttttcttttt ttattctatt attgacaagt caatcgttga
     8881 cgagtcaatt attagaaagg aggaaattat gtctttagaa gagattagtc accttttata
     8941 tcaaatcaaa ttagccgatc aaaaaatcgt ccagatcttt gaagaaaata tcggtataag
     9001 tcttactaga tacgagatca tgatgagact gaaagaagaa aatccattgc tacaaagcag
     9061 tttgcaagaa aagttgcaga ttgatcaagg agcagttact cgtcatctga aggtattgga
     9121 agcaaatggc tatgtttcgc gtcagagaaa tcctcagaac aaccgggaag tgtatgtagc
     9181 gctaacagaa aaagcccaga agaaaatcga gcattgtgaa atggaccata aagatacagg
     9241 ttccgtgcta tccccggctt tcagcgatgt agaaatgaaa caatttctaa cacttttaga
     9301 taaattgaat acccaacttt gcaatataac aacagaaacg aaagaggtta ataataatgg
     9361 aacaaaaaaa tgatttttca acaattatga ctggtagaag atccgttcgc gtatatgatg
     9421 aaacatacaa aatcccacac gaagaaatgc tggaaatgat caaagaagcg acgactgcac
     9481 cttcttctgt caatatgcaa ccatggcgct ttgtggtcgc tgaaagcgag gaagcaaaag
     9541 aaatcttgcg tcctttgatc cgtttcaata cgagacaaaa tgatacttct tctgcaatgg
     9601 tcatgatttt tggcgatatg caatgttacg aatatggcga agaaatctat aaccaagctt
     9661 acgaatcagg gaagatgcca aaagaagtca gagatcaaca attagctgcg atcattcctt
     9721 attacaagag tttttcaaga gaagaaatga acgatgtagt caaagtcgat tctagcttag
     9781 cggctatgca attcatgtta gttacgcgtg atcatggcta tgaaacaaat ccaattggtg
     9841 gagtcgaagc agatcagttg gcagaggcat ttggtttgga taaagaccgt tatgttccag
     9901 ttattatttt atcaatagga aaagcggtag aagaaggtta cgagtctgtt cgtttagcac
     9961 cagaaaagat cactacgttc gaataaaagg ttttcagtta ctattcagta gctattgctt
    10021 tttttgaatc gtgtgtggta acctaataaa aaaggaggtc ggaaaaatga ctgcatcgat
    10081 gaaattacgt ttcgaacttt tgaataacaa ctaaataaat tcaaaagaca tgtataaaca
    10141 acaatttcat ggatggagta tgtccatttt ttcgaacgac agtagaatag gtgaaagcta
    10201 tgacagattt ggtgatttag tcatagttat ttcgttcaga gtaggaaaag atgtgatgca
    10261 gtttttttgc aaacagattt ttctgctctt ttttagtatc gataattgtt gttttacatg
    10321 aaataggagt gtaaaacata tggaaaattt agcagtaaat ataacaaatc tacaagtcag
    10381 ctttggcaac cagctagaac tatctattga ttctcttcgt gtctatcagc aagatcgtat
    10441 agggatcata ggagaaaatg gtgtcggtaa atcgactttg ctcaaactaa tagccggtga
    10501 actttttccc gatcatggga aaatccaaac agagatcacc ttcaactacc tgcctcaatt
    10561 aacctatctc gctgaagcaa aggacctaaa tttggaatta gccagtcatt tccagttaag
    10621 actggaagaa acttcagagc ggaaatggag cggaggggaa gaacgaaaga tcgagttgat
    10681 acgtcttctt tcttcttatg aacaagggat gcttctagac gagccaacaa cccatctaga
    10741 tagaaaaagt attgatcgac tgattgaaga gcttcgttat tattatggta cgctggtttt
    10801 tgttagtcat gatcgctatt ttctagatga gctagcatcg aaaatctggg aagtaaaaga
    10861 cggagaaatc cgagagtttt cggggaatta tagtgcctat ctcactcaaa aggaattgga
    10921 gaaaaagact cagctacgag aagcagagtc gatcatgaaa gagaaaaaac gattggaaaa
    10981 atcgatccaa gaaaagaaaa aacaagcgga aaagttggaa aaagtgtcca gtaaaaagaa
    11041 aaagcaacaa atcagaccgg atcggttgtc ttcctctaaa caaaaagaca gtgtacaaaa
    11101 agccatccaa aagaatgcga aaacattaga gagaagactc caaaaaatag gagaaacaac
    11161 caagccgcag cagatgaaac aaatccgttt tccagtacca aaatctcttg aactccacag
    11221 ccgctatccc atcatgggac aaaatgtcca attggaaaga agtgggagaa cattactggt
    11281 aaatggtgat tttcagtttt ctttaggtaa aaaaatcgcg attgtcggtg aaaatggttc
    11341 aggtaagaca accttattag aacatatccg caaacaagga gaaggaatcc ttctctctcc
    11401 gaaagtaagc tttcaagtat atcagcaaaa gggttatcaa atgacatctg aagaatccat
    11461 cattcgtttt gtcatgagac aaacagagtt ttcagaatcg cttgtccgta gtttgctgaa
    11521 tcacttaggg tttgctcagg aaactttgac gaaaccgtta tgtacattaa gtgggggaga
    11581 agcgacccgt ctgacgattg ctttgctttt tactaagcca agtaatgtgt tgctgttaga
    11641 tgaaccgact aattttattg atatggcaac gatcgaagct ttagagaagc taatgcaaat
    11701 atatccggga acgattttgt ttacttctca tgattcttac tttgtcgagc gtacggctga
    11761 tgaagtttat gaaataaaag ggcagaaaat aaaaaaagta cttacgagaa atttttaaat
    11821 gtgctacgat gattttcgtg acaaatttaa aggagtggta cagattgcct acaaataaaa
    11881 aagaaggaat aatttttaca acaatgatgt gttttttgat ggtcttgggg atgagcgcgt
    11941 ataatttatg gctgcatcaa gatcttcatt tatcaagttt gttgattggt ctagtgcctg
    12001 gattcgtggt ggctttcatt ttggatgtct tcatcatcgg tgtgctggcg aaaaaaattg
    12061 cctttaaact accagtaaat ccagaaagca aggtccaaat gatcttaact atttcatgct
    12121 tgatggtttt aggaatggtg acatgtatgt ctttattcgg tgtgatcatg gaacaaggaa
    12181 tacctgatca attattctct gcttatatga atgcttggaa aatgaatgtg attgccgctt
    12241 taccgttgca gttgatcatc gttggcccgc tttcaagaag tgtgctaaaa gcaattcaaa
    12301 gtaatgaatg atggaacact gttatttgaa aaaaggcctt ggcatgcttt ttgtcatagt
    12361 ctcttgaatg cagttctaga aaaatagtga tccgaacgat aggttttggc ctgtcgttcg
    12421 gatcgctttt tcttttccaa ctgtattgct cttttattga agataatttg ctcttcaata
    12481 gatatttcta gaaaggttct gtttatccct tactcaaaaa actgctgcat ttgttctctt
    12541 acttgctgac accattggag ttcctgctga caaagcataa ttctgcgctg gatcacaaca
    12601 taacgtccaa attcttgttt cttgtctagc gagaggtcat tcaatttttt ttgatttttt
    12661 tgcatgattt tgttcagctg ttgttctcta gtgaatagca gtccagtagc tgttgtttta
    12721 tcgagcgtcg aaaaagcata gatttttgct agaaattcat ctttttgcgt aggagcggga
    12781 gtttcctctt tgatccattc ctctacaaga gcacgtcctt catcagtcaa gtggtagatc
    12841 tttttttgag agtgctcgtc tttgtccaaa acggtcacat aaccctgctg gtctaacttg
    12901 gcaagcgttg tatagatctg actgtgatgg gcttcccaaa aaattgtgat cagctgcttc
    12961 aattcatacc cagaacgtgg tttggataaa agcacgcata ataatatata ggctaaagta
    13021 ttcataaaaa tcctacctct cgtcttattt tctttattat atcacagtaa agtttccacg
    13081 ttttacatgt gcatatttac atgtaaaata aatcatgtat gatgctaata gagagaaagg
    13141 gatggaaata ttggagaatc aaatagatat acaagaacaa acaaatgaag aaacaaaggg
    13201 gaaaagttca gcgctagttg tagcagctac ctgtatgatc gcttttatgg gagtgggtct
    13261 agtagaccca atcttaaaaa cgattgctgc acagttaaac gctacgccag ctgaaacgac
    13321 cctgttattt actagttaca tgttagtcac tggtgtggtg atgctattta caggtttctt
    13381 atctagtcgg atcggtttga aaaaaacatt gatgacagga ttgtttatca tcgttgtatt
    13441 cgctggtctt ggcggattat ctgggaatat cggaatgctg attgggttac gtgccggctg
    13501 gggtgtcggg aatgctttat ttgtctctac tgctttagca acgatcgtca gtattttagt
    13561 tggtaacaca gaaaaagcaa tcatgatgta tgaagcagca cttggctgcg gaatggctgt
    13621 tggccctcta gtcggtgggg tcttgggcag tggttcatgg cgttatccat tttttggggt
    13681 agcatttttg atgttttgcg gttttatagc cctagcggta cttttacctg aaactgagaa
    13741 accaaagaga aaagtaggcc tttgggaagg tgtcaaagcg ttaagcaatc ataaacttcg
    13801 ttcagttgga ctaatcgcat tgttatataa tttcggattc tttactttac ttgcgtatgc
    13861 gccattttta ttgattggct attctgaatt agaagtcggt tttgtatttt ttggctgggg
    13921 tgtgcttctg gctattgctt cgattttcgt tgcaccggct cttgagcgga agtttacgac
    13981 ttatcggaca attttagcag catttgtctt attcattatt tgtttgctgt tattaggagc
    14041 tggaacttct atgccagtcc ttgtaccgat cagcattgtg ttagcaggat ttttccaagg
    14101 aattatcaat acactgttga cgacgattgc tatggaaata ccaggtctgc aacgaaacgt
    14161 tgcttcgtcc agctatagtt ttgtccgctt tttcggtgga gctttagcac catttattgc
    14221 aggtgtgatt ggtgaacata ttggtgaaag ctatgcgttt tattttgcag gtgccattgt
    14281 tcttatcagt gtatgttgta tcatttatca ccgtaattat tttgctacaa atgaagaaga
    14341 ataagaaatc agaggttgtg aaaaagctgt cctgcatcaa gtcataagaa
//
LOCUS       DADQDV010000275         6571 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.guided.117, whole genome shotgun sequence.
ACCESSION   DADQDV010000275 DADQDV010000000
VERSION     DADQDV010000275.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6571)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6571)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6571
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.guided.117"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            complement(75..1367)
                     /locus_tag="J8S10_003269"
     CDS             complement(75..1367)
                     /locus_tag="J8S10_003269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAZ9631763.1"
                     /translation="MSYTHLIKETLDILDLSVTFNENCLTKEKYKGQICHIYRGNLIY
                     TAQECIHCKHQIASDIVRWGTTTVRLLMNDVSEYRTYLELKKQRFKCKACQRTFVADT
                     SVAKKHCFISEKVRWSVVTRLKKNTSMTEIAAQKNLSVSSVYRIMKRFYRPLNPFRTP
                     LPKVLCFDEFKSVRGVSGAMSFIMMDGQTQRLLDIVENRQLPFLKRYFSHFSREIREA
                     VEWIVIDMYAPYVSLVKKLFPKAQLIIDRFHIVQHIGRTFRNHRIKETNQLLKSKEQK
                     HYQLGKQLKRYWKLLQKDERKLDYTRRLWRPGFKAHLTETDIVDRLLKGSPALRVGYQ
                     LYQDFLYAVKERDYVSFEELLTNNIMLPEGYQTTLRTFQKFLPQIKNALQQSYSNGPL
                     ECLNNHIKVLKRNAYGFRSFYNFKLRIMIRHGNALIFN"
     gene            1699..2667
                     /locus_tag="J8S10_003270"
     CDS             1699..2667
                     /locus_tag="J8S10_003270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HAZ9631764.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            2660..3691
                     /gene="vanA"
                     /locus_tag="J8S10_003271"
     CDS             2660..3691
                     /gene="vanA"
                     /locus_tag="J8S10_003271"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HAZ9631765.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALAVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            3697..4305
                     /locus_tag="J8S10_003272"
     CDS             3697..4305
                     /locus_tag="J8S10_003272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HAZ9631766.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            4733..5644
                     /gene="vanY"
                     /locus_tag="J8S10_003273"
     CDS             4733..5644
                     /gene="vanY"
                     /locus_tag="J8S10_003273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-A/VanY-F/VanY-M family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HAZ9631767.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYELWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            5797..6282
                     /gene="vanZ"
                     /locus_tag="J8S10_003274"
     CDS             5797..6282
                     /gene="vanZ"
                     /locus_tag="J8S10_003274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HAZ9631768.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
BASE COUNT         2053 a         1139 c         1437 g         1942 t
ORIGIN      
        1 ttgtcaaatg atgttggtaa agagaaatct tagaataatt ggagatcaag tggatcagtt
       61 cctcttgatc ttttttagtt gaaaatcaat gcgttgccat gacgaatcat gatgcgcaat
      121 ttgaaattat aaaagctacg aaagccatat gcatttcgtt ttaacacttt gatatggttg
      181 ttcagacatt caagtgggcc atttgaataa ctttgttgta aagcattttt gatttgtggc
      241 agaaatttct ggaacgttct caaggtcgtc tgatagcctt cgggaagcat gatattattg
      301 gtaagtagtt cttcaaacga tacgtagtct cgttccttta cagcgtaaag aaagtcttga
      361 tataactgat agcctacacg caaagcaggg ctccctttca gtaagcgatc cacaatatcg
      421 gtctctgtta aatgagcttt gaagccaggt cgccaaaggc gtcgagtata atcaagcttg
      481 cgttcatctt tttgaagaag tttccagtat ctttttaatt gcttacctaa ttgatagtgt
      541 ttttgttctt tgctttttaa tagttggttc gtttctttga ttcgatgatt gcgaaaggta
      601 cgaccaatat gttggacgat gtgaaaccgg tcaataatca gctgtgcttt tggaaacagc
      661 tttttaacga gcgatacata aggagcgtac atatcaatca cgatccattc gaccgcttca
      721 cgaatttctc gtgaaaaatg actaaaataa cgttttaaaa aaggcagttg tcggttctcg
      781 acaatgtcca ataagcgctg tgtttgtcca tccatcatga tgaaactcat agcacctgaa
      841 acaccccgaa ctgatttgaa ttcatcaaaa caaagtacct taggtaacgg tgtccgaaaa
      901 ggattcaacg gacgataaaa tcgcttcata atacggtaaa cagaagagac cgatagattt
      961 ttctgagcgg cgatctctgt cattgaggta ttttttttca gacgagtcac gacagaccag
     1021 cggactttct cactgatgaa acaatgtttt ttcgcaacag aagtatctgc gacaaaggtc
     1081 cgctgacaag ctttgcattt gaagcgttgc tttttcaatt cgaggtaggt acggtattca
     1141 gaaacatcgt tcattaacaa ccggacggtt gttgtacccc aacgcacaat atctgaagca
     1201 atctggtgtt tacagtggat gcattcttgg gctgtataaa tcaagtttcc acgataaata
     1261 tgacagattt gccctttgta tttttctttt gtgagacaat tttcgttaaa agtaactgat
     1321 aagtctagaa tatctaatgt ttctttgata aggtgagtgt aagacatctt gattcctcct
     1381 tttgggttgg ttcgccaaat taattctaaa ggatttcaag gtgtcttttc tatatgtttt
     1441 ggaaaataaa aaagatgctg gtgtcatcca ccaacatcaa aaagtataga gccataattt
     1501 tttaggaaaa tctcaaggtt atctttactt tttcttagga aattaacaat ttaatattaa
     1561 gaaacggctc gttcttacac ggtagactta ataccgtaag aacgagccgt tttcgttctt
     1621 cagagaaaga tttgacaaga ttaccattgg catccccgtt ttatttggtg cctttcacag
     1681 aaagggttgg tcttaattat gaataacatc ggcattactg tttatggatg tgagcaggat
     1741 gaggcagatg cattccatgc tctttcgcct cgctttggcg ttatggcaac gataattaac
     1801 gccaacgtgt cggaatccaa cgccaaatcc gcgcctttca atcaatgtat cagtgtggga
     1861 cataaatcag agatttccgc ctctattctt cttgcgctga agagagccgg tgtgaaatat
     1921 atttctaccc gaagcatcgg ctgcaatcat atagatacaa ctgctgctaa gagaatgggc
     1981 atcactgtcg acaatgtggc gtactcgccg gatagcgttg ccgattatac tatgatgcta
     2041 attcttatgg cagtacgcaa cgtaaaatcg attgtgcgct ctgtggaaaa acatgatttc
     2101 aggttggaca gcgaccgtgg caaggtactc agcgacatga cagttggtgt ggtgggaacg
     2161 ggccagatag gcaaagcggt tattgagcgg ctgcgaggat ttggatgtaa agtgttggct
     2221 tatagtcgca gccgaagtat agaggtaaac tatgtaccgt ttgatgagtt gctgcaaaat
     2281 agcgatatcg ttacgcttca tgtgccgctc aatacggata cgcactatat tatcagccac
     2341 gaacaaatac agagaatgaa gcaaggagca tttcttatca atactgggcg cggtccactt
     2401 gtagatacct atgagttggt taaagcatta gaaaacggga aactgggcgg tgccgcattg
     2461 gatgtattgg aaggagagga agagtttttc tactctgatt gcacccaaaa accaattgat
     2521 aatcaatttt tacttaaact tcaaagaatg cctaacgtga taatcacacc gcatacggcc
     2581 tattataccg agcaagcgtt gcgtgatacc gttgaaaaaa ccattaaaaa ctgtttggat
     2641 tttgaaagga gacaggagca tgaatagaat aaaagttgca atactgtttg ggggttgctc
     2701 agaggagcat gacgtatcgg taaaatctgc aatagagata gccgctaaca ttaataaaga
     2761 aaaatacgag ccgttataca ttggaattac gaaatctggt gtatggaaaa tgtgcgaaaa
     2821 accttgcgcg gaatgggaaa acgacaattg ctattcagct gtactctcgc cggataaaaa
     2881 aatgcacgga ttacttgtta aaaagaacca tgaatatgaa atcaaccatg ttgatgtagc
     2941 attttcagct ttgcatggca agtcaggtga agatggatcc atacaaggtc tgtttgaatt
     3001 gtccggtatc ccttttgtag gctgcgatat tcaaagctca gcaatttgta tggacaaatc
     3061 gttgacatac atcgttgcga aaaatgctgg gatagctact cccgcctttt gggttattaa
     3121 taaagatgat aggccggtgg cagctacgtt tacctatcct gtttttgtta agccggcgcg
     3181 ttcaggctca tccttcggtg tgaaaaaagt caatagcgcg gacgaattgg actacgcaat
     3241 tgaatcggca agacaatatg acagcaaaat cttaattgag caggctgttt cgggctgtga
     3301 ggtcggttgt gcggtattgg gaaacagtgc cgcgttagct gttggcgagg tggaccaaat
     3361 caggctgcag tacggaatct ttcgtattca tcaggaagtc gagccggaaa aaggctctga
     3421 aaacgcagtt ataaccgttc ccgcagacct ttcagcagag gagcgaggac ggatacagga
     3481 aacggcaaaa aaaatatata aagcgctcgg ctgtagaggt ctagcccgtg tggatatgtt
     3541 tttacaagat aacggccgca ttgtactgaa cgaagtcaat actctgcccg gtttcacgtc
     3601 atacagtcgt tatccccgta tgatggccgc tgcaggtatt gcacttcccg aactgattga
     3661 ccgcttgatc gtattagcgt taaaggggtg ataagcatgg aaataggatt tactttttta
     3721 gatgaaatag tacacggtgt tcgttgggac gctaaatatg ccacttggga taatttcacc
     3781 ggaaaaccgg ttgacggtta tgaagtaaat cgcattgtag ggacatacga gttggctgaa
     3841 tcgcttttga aggcaaaaga actggctgct acccaagggt acggattgct tctatgggac
     3901 ggttaccgtc ctaatcgtgc tgtaaactgt tttatgcaat gggctgcaca gccggaaaat
     3961 aacctgacaa aggaaagtta ttatcccaat attgaccgaa ctgagatgat ttcaaaagga
     4021 tacgtggctt caaaatcaag ccatagccgc ggcagtgcca ttgatcttac gctttatcga
     4081 ttagacacgg gtgagcttgt accaatgggg agccgatttg attttatgga tgaacgctct
     4141 catcatgcgg caaatggaat atcatgcaat gaagcgcaaa atcgcagacg tttgcgctcc
     4201 atcatggaaa acagtgggtt tgaagcatat agcctcgaat ggtggcacta tgtattaaga
     4261 gacgaaccat accccaatag ctattttgat ttccccgtta aataaacttt taaccgttgc
     4321 acggacaaac tatataagct aactctttcg gcaggaaacc cgacgtatgt aactggttct
     4381 tagggaattt atatatagta gatagtattg aagatgtaag gcagagcgat attgcggtca
     4441 ttatctgcgt gcgctgcggc aagatagcct gataataaga ctgatcgcat agaggggtgg
     4501 tatttcacac cgcccattgt caacaggcag ttcagcctcg ttaaattcag catgggtatc
     4561 acttatgaaa attcatctac attggtgata atagtaaatc cagtagggcg aaataattga
     4621 ctgtaattta cggggcaaaa cggcacaatc tcaaacgaga ttgtgccgtt taaggggaag
     4681 attctagaaa tatttcatac ttccaactat atagttaagg aggagactga aaatgaagaa
     4741 gttgtttttt ttattgttat tgttattctt aatatactta ggttatgact acgttaatga
     4801 agcactgttt tctcaggaaa aagtcgaatt tcaaaattat gatcaaaatc ccaaagaaca
     4861 tttagaaaat agtgggactt ctgaaaatac ccaagagaaa acaattacag aagaacaggt
     4921 ttatcaagga aatctgctat taatcaatag taaatatcct gttcgccaag aaagtgtgaa
     4981 gtcagatatc gtgaatttat ctaaacatga cgaattaata aatggatacg ggttgcttga
     5041 tagtaatatt tatatgtcaa aagaaatagc acaaaaattt tcagagatgg tcaatgatgc
     5101 tgtaaagggt ggcgttagtc attttattat taatagtggc tatcgagact ttgatgagca
     5161 aagtgtgctt taccaagaaa tgggggctga gtatgcctta ccagcaggtt atagtgagca
     5221 taattcaggt ttatcactag atgtaggatc aagcttgacg aaaatggaac gagcccctga
     5281 aggaaagtgg atagaagaaa atgcttggaa atacgggttc attttacgtt atccagagga
     5341 caaaacagag ttaacaggaa ttcaatatga actatggcat attcgctatg ttggtttacc
     5401 acatagtgcg attatgaaag aaaagaattt cgttctcgag gaatatatgg attacctaaa
     5461 agaagaaaaa accatttctg ttagtgtaaa tggggaaaaa tatgagatct tttattatcc
     5521 tgttactaaa aataccacca ttcatgtgcc gactaatctt cgttatgaga tatcaggaaa
     5581 caatatagac ggtgtaattg tgacagtgtt tcccggatca acacatacta attcaaggag
     5641 gtaaggatgg cggaatgaaa ccaacgaaat taatgaacag cattattgta ctagcacttt
     5701 tggggtaacg ttagcttttt aatttaaaac ccacgttaac taggacattg ctatactaat
     5761 gatacaactt aaacaaaaga attagaggaa attatattgg gaaaaatatt atctagagga
     5821 ttgctagctt tatatttagt gacactaatc tggttagtgt tattcaaatt acaatacaat
     5881 attttatcag tatttaatta tcatcaaaga agtcttaact tgactccatt tactgctact
     5941 gggaatttca gagagatgat agataatgtt ataatcttta ttccatttgg cttgcttttg
     6001 aatgtcaatt ttaaagaaat cggattttta cctaagtttg cttttgtact ggttttaagt
     6061 cttacttttg aaataattca atttatcttc gctattggag cgacagacat aacagatgta
     6121 attacaaata ctgttggagg ctttcttgga ctgaaattat atggtttaag caataagcat
     6181 atgaatcaaa aaaaattaga cagagttatt atttttgtag gtatactttt gctcgtatta
     6241 ttgctcgttt accgtaccca tttaagaata aattacgtgt aagatgtcta aatcaagcaa
     6301 tctgatcttt catacacata aagatattga atgaattgga ttagatggaa aacgggatgt
     6361 ggggaaactc gcccgtaggt gtgaagtgag gggaaaaccg gtgataaagt aaaaagctta
     6421 cctaacacta tagtaacaaa gaaagcccaa ttatcaattt tagtgctgag gaattggtct
     6481 ctttaataaa tttccttaac gttgtaaatc cgcattttcc tgacggtacc cccaaactaa
     6541 gatttcatag atagattttc tgataacttt a
//
LOCUS       DADQDV010000276         4640 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.guided.143, whole genome shotgun sequence.
ACCESSION   DADQDV010000276 DADQDV010000000
VERSION     DADQDV010000276.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4640
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.guided.143"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            244..1458
                     /locus_tag="J8S10_003275"
     CDS             244..1458
                     /locus_tag="J8S10_003275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HAZ9631769.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            1489..1707
                     /locus_tag="J8S10_003276"
                     /pseudo
     CDS             1489..1707
                     /locus_tag="J8S10_003276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173391.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2126..2599
                     /gene="dfrF"
                     /locus_tag="J8S10_003277"
     CDS             2126..2599
                     /gene="dfrF"
                     /locus_tag="J8S10_003277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrF"
                     /protein_id="HAZ9631770.1"
                     /translation="MIGLIVARSKNNVIGKNGNIPWKIKGEQKQFRELTTGNVVIMGR
                     KSYEEIGHPLPNRMNIVVSTTTEYQGDNLVSVKSLEDALLLAKGRDVYISGGYGLFKE
                     ALQIVDKMYITEVDLNIEDGDTFFPEFDINDFEVLIGETLGEEVKYTRTFYVRKK"
     gene            2726..3382
                     /locus_tag="J8S10_003278"
     CDS             2726..3382
                     /locus_tag="J8S10_003278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005603505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HAZ9631771.1"
                     /translation="MNKEWSELNKTMQAQIKKKDTYKRGIDTLLTLRSQLIQTLVSFK
                     EELCREDFNSIPFINADGYHSKTIAYSIWHIFRIEDIVVHTVINEDEQVFFAGNYQER
                     INSPIITTGNELMKQQIADFSKQLNLEELYLYIFEVWESTEKMLERLSYDELKRKIPK
                     ERKGYLESLNVVNDNEKAIWLIDYWCNKDICGLIQMPFSRHWIMHTEACLRIKNKIHS
                     "
     gene            3564..4094
                     /locus_tag="J8S10_003279"
     CDS             3564..4094
                     /locus_tag="J8S10_003279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAZ9631772.1"
                     /translation="MRKVVLFIAMSLDGYIADGNGGVAWLNGHGNDNENIDTYTEFTK
                     DIDTVLMGWNTSHQVVTELSPQEWVYNKFTTYVLTHKECNSSQQIHFTSENPVLLLER
                     LKQEAGKDIWICGGANLVQQLVSKNMIDKYYISVIPTLLGNGVRLLGNIDREIKLRLC
                     KTQTYNGITDLIYMRR"
BASE COUNT         1550 a          668 c          985 g         1437 t
ORIGIN      
        1 tctttattcc ttatgaaaaa atatctttaa aaataaaaaa agacgaaaat aaacggtttt
       61 ctataaaaag aagaccgttt attttttgtc tttatttgtg tgaaaaacga aaaagagcac
      121 aacacatcaa gcttttatta attgtctgtc ttttataaat gcaagtatta attcaaaaaa
      181 acagaagaaa aaaacaacta caccttcttt tatactcgta atcgtagaaa ggaggcgaaa
      241 aaaatgaata cattacctat caatacagga gatacagcat tcatgatttt atgtacagca
      301 atggtttgcc tgatgactcc tggtctagct tttttttacg gcggattagc acggaagaat
      361 aatatactaa cgatcatgtc tcaatctttt ctctccgttg ggataacaac gattatgtgg
      421 gtatttggtg gattcggatt ggcctttgga cgggatatcg gcggtgttat tggaaacccg
      481 gcagatttct ttttgatgag acatgttaca agcttcccca acatgtttca tggtgcaacg
      541 attccatttt taatgttctt tctttaccaa ctgatgttta tcgtgattac cgttcctttg
      601 atgacaggag cttttgcagg gagattgaat ttaaaaggct atattatact tgttattttt
      661 tggaatctgc tgatttattt ccctgtttgc cactggatat ggggtggcgg atttttggat
      721 cagatgggat ttagagattt cgctggtgga gcagtcatcc acacgacagc tggattcggc
      781 tctttagcat gtatcctcac acttggtcaa agaaagattc ctttaggaga aagaagtcag
      841 catagcagtc ttatggcagc tgctatcggt acaggactgc tttggtttgg ctggttcggt
      901 tttaattccg gtggtgcact tcgagcagat gaacaagcag tcaatgcatt tggttcaaca
      961 ttcatcgctc ttgcatttgc gatgattact tggctgatca ttgcaaaagt aaaaggaaat
     1021 ggctttgatt ttgtcgacgt actaacagga tccgttgctg gattggcagc cattacgcct
     1081 tgtgccggtt atgtagaagc aaaaagtgcc atgctgattg ggatcattgc gggtatcgtc
     1141 tgtcatgctg ctgttgattt tcgtaaaaag aaacaatggg atgatgcact tgatgtgtgg
     1201 ggtgttcatg gcatgggcgg attcacaggt acgattctga tagggatctt tgcatctaac
     1261 agccatttac taacgaatcc aagcagctgg tacttcttag ggattcaagt gattggtgtc
     1321 atcattactg ccgtgtatgc ctatgtgctg acaacagtga ttttaaaatc ggcgatgcac
     1381 tttacaacga tcactactac aaaagaagaa caagaagaag gattggactt tttcttcttt
     1441 ggcaacaaac tcaattgaaa caaattcaaa tagaaaagag gaagattcat gcaacaaagc
     1501 aaaacgaaaa ttcctgcaaa aaaattaacg ttctttggct ttttggctat gaccatctca
     1561 atggtcgttt cattatatga atatcccaca ttcgcgacct caggcttcag cttagtattt
     1621 ttcttgttat taggcggttt gctatggttt atccctgtgg cattgtgcgc agcagagatg
     1681 gcaacggtga aaggatggga aaaaggtgtt tcccaaacaa aaagatatta agaaacagcc
     1741 catgtttacc tgcttgcaaa caaaagaata ttgctactag actaagagat actacataag
     1801 tgtgttggta tctctttttt gttgccgtga aacagcagac tatttcattt ctgcttgatt
     1861 accttaaaac ttattagtct atggtttgtc aagggcttgt tgcgtgagaa atgctgaata
     1921 tcacccttta caaaacatag gctgataagt aacttttcaa aagcagaaaa gaaatggcaa
     1981 tgcttataac aatatgatat aatgcagatg aagacaaaaa aggaatttgt cgagctggtt
     2041 agttcgagat aattttgagt ttgttaagat gtggtgcact tgatggaatc acaggtacga
     2101 catcatatta tggaggatga aatagatgat aggtttgatt gttgcgaggt caaagaataa
     2161 tgttataggc aagaatggta atataccatg gaaaataaag ggagaacaaa agcaatttag
     2221 agagttaaca acgggtaatg tggttattat ggggcgaaag tcttatgaag aaatcggtca
     2281 tccgttgcct aatagaatga atattgttgt ttccaccaca acagagtatc aaggagataa
     2341 tttagtttca gttaaatcat tagaagatgc attattattg gctaaaggac gagatgtata
     2401 catatctggt ggatatggac tatttaagga agctttgcaa atagtagata aaatgtatat
     2461 cacagaagta gatttaaata ttgaagatgg agatacattc tttccagaat ttgatatcaa
     2521 tgattttgaa gttttgatag gggaaacact tggtgaggaa gtgaaatata cgagaacatt
     2581 ttatgtaagg aaaaaatgaa ttgagtaaat tttggattta gggtgttttc ataaatatat
     2641 tgctttttat gcatatataa attgttgtaa gacaaattcc agtttgtatg gggcgataaa
     2701 atcagaattt gagagaggat tgaatatgaa taaggaatgg tctgaactta ataaaacaat
     2761 gcaggcacaa ataaaaaaga aagatactta taagaggggt attgatactt tacttacttt
     2821 acgaagtcag ttaatacaaa ccttagtatc tttcaaagaa gaattatgca gagaagattt
     2881 taactcaatc cccttcataa acgctgatgg ttatcatagt aagacgattg cttattctat
     2941 ttggcatatt ttccgcattg aagatatagt tgtgcataca gtgataaatg aagatgaaca
     3001 agtatttttt gcaggcaatt atcaagagcg tatcaattca cctatcatta caacaggaaa
     3061 tgaactcatg aaacagcaga ttgcagactt ttcaaaacag cttaatctgg aagaattata
     3121 tttatatatt ttcgaagtat gggaaagcac tgagaaaatg cttgaacggt tatcttatga
     3181 tgaattgaaa agaaaaatac cgaaagaaag aaaaggatac ttagaatcgt tgaatgtagt
     3241 aaacgacaat gaaaaagcaa tttggctgat tgattattgg tgtaataaag atatttgtgg
     3301 actaattcaa atgccgtttt caagacattg gattatgcac acagaagcct gtttgcgtat
     3361 aaagaacaag atacattcat aggcaaaaat ttcagtttgt agaactaagg aaattggaat
     3421 ttaaggagga ataaagtatg gttagtgatt ttataagagc agcatttcca tggattttaa
     3481 tgggtttatt tgtagcaatc agttgttccc ttatgagtaa aaaagagaaa taaattcctg
     3541 tttgtattta taaaagagaa aaaatgagaa aagtagtttt atttattgcc atgagccttg
     3601 acggatatat tgcggacggt aatggtggag tagcttggct aaatggtcat ggaaatgaca
     3661 atgaaaacat cgacacttat acagaattta ccaaagatat agatactgtc ttaatggggt
     3721 ggaatacttc tcatcaggtt gttactgaac tttctccgca agaatgggta tataataaat
     3781 ttacaactta tgtattaaca cataaagagt gcaattcttc ccaacaaatt cattttacaa
     3841 gtgaaaatcc tgttttatta ttggaacggc taaaacaaga agcaggaaag gatatttgga
     3901 tttgtggcgg agcaaatctt gttcagcagt tggtaagcaa aaatatgatt gataaatatt
     3961 acatttctgt tattcctact ctgttaggaa atggggttcg tcttttgggc aacatagaca
     4021 gggaaataaa gttaaggctt tgtaaaacac agacttataa cggaataacc gatttgattt
     4081 atatgcgtag ataactagag agaaacagaa aagctgttaa accgacggag cgatccgacc
     4141 acgttggcgg gaaaatcctt aagatttttc cgccatgctt gcaagggggc ggttcgcttc
     4201 ggcggttcgg cgagcttgcg agccgttcaa agcccccgtt atctaacaag gggggcacaa
     4261 aaaacaagaa acactataca ctaacaagcg gaaaacgctg tatttataag gcaaaacccc
     4321 atttttacag tagtgatata aattgtacct atatcactat gaaaattgaa tagtaaatat
     4381 gagaaagaca gttgatttca aaaaataaga aattgattgt cgttttcttt tgcagaaatt
     4441 taagtgcagg caattatggt agttgtcgta attgctgtca gctcagtgtt tatcactgat
     4501 ggtgtgaaag atttacggtt ggagatgttc aataagatta ttggtgctta attattttta
     4561 ttgtagtgct gatatgagaa tgttataatt ggggtataaa acatacaaat aaatttgctg
     4621 aaaaatgagg tatcaaaata
//
LOCUS       DADQDV010000277         3950 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.guided.155, whole genome shotgun sequence.
ACCESSION   DADQDV010000277 DADQDV010000000
VERSION     DADQDV010000277.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3950)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3950)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3950
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.guided.155"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            56..790
                     /locus_tag="J8S10_003280"
     CDS             56..790
                     /locus_tag="J8S10_003280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008766909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAZ9631773.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            823..1731
                     /locus_tag="J8S10_003281"
     CDS             823..1731
                     /locus_tag="J8S10_003281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HAZ9631774.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            1728..2270
                     /gene="sat4"
                     /locus_tag="J8S10_003282"
     CDS             1728..2270
                     /gene="sat4"
                     /locus_tag="J8S10_003282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HAZ9631775.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            2363..3157
                     /locus_tag="J8S10_003283"
                     /note="aph(3')-IIIa"
     CDS             2363..3157
                     /locus_tag="J8S10_003283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HAZ9631776.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            complement(3265..3453)
                     /locus_tag="J8S10_003284"
                     /pseudo
     CDS             complement(3265..3453)
                     /locus_tag="J8S10_003284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913594.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3433..>3950
                     /locus_tag="J8S10_003285"
     CDS             3433..>3950
                     /locus_tag="J8S10_003285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAZ9631777.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLE
                     EAGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAM
                     YKIKSILKHGEKNYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPA
                     SGGQEPESRMIEP"
BASE COUNT         1351 a          600 c          919 g         1080 t
ORIGIN      
        1 gaagtgaatg aaattgtatc ggagataaat aactttttaa acgaggagag ttcagatgaa
       61 agaaaacaaa tatgatgata atatattttt tcaaaaatac agtcaaatga gtcgctcgca
      121 gaaaggactg gctggtgcgg gagaatggga gactttgaaa aagatgctac ctgattttaa
      181 gggtaagcgt gtgcttgatt taggatgcgg ctatggatgg cactgtatat atgcgatgga
      241 aaacggtgct tcctctgtag taggtgttga tatttctcat aaaatgctcg aagtagcaaa
      301 aggaaaaacc cattttccac agattgaata tgaatgctgt gccatagaag atgtggattt
      361 cccagaggag agctttgatg taatactaag ttcgcttgcg tttcattatg tagcagacta
      421 tgagaattta ataaaaaaga tatataggat gctgaaggct ggtggcaatt tagtttttac
      481 agttgaacat cctgttttta ctgctcatgg aacacaagac tggtattata acgaaaaagg
      541 agaaatactg catttcccgg tggacaatta ttattatgag ggcaaacgga cagctatgtt
      601 tttggaagaa aaggttacaa aatatcatag aacactgacc acatatctaa atacactgct
      661 ttcaaatagt tttataataa atcagattgt ggagccacag ccgccagaga acatgatgga
      721 tattccgggg atggcggatg aaatgcgacg cccaatgatg ctgattgtat cggcaaaaaa
      781 gaagatgtaa taatatagaa aaaataaacg aggagtatgt aaatgagatc agaaaaagaa
      841 atgatggatt tagtactttc tttagcagaa caggatgaac gtattcgaat tgtgaccctt
      901 gaggggtcac gcgcaaatat taatatacct aaagatgaat ttcaggatta tgatattaca
      961 tattttgtaa gtgatataga accgtttata tctaatgatg actggcttaa tcaatttggg
     1021 aatataataa tgatgcaaaa gccggaggat atggaattat tcccacctga agaaaaggga
     1081 ttttcctatc ttatgctatt tgatgattac aataaaattg atcttacctt attgcccttg
     1141 gaagagttag ataattacct aaagggcgat aaattaataa aggttctaat tgataaagat
     1201 tgtagaatta aaagggacat agttccgact gatatagatt atcatgtaag aaagccaagc
     1261 gcaagggagt atgatgattg ctgcaatgaa ttttggaatg taacacctta tgttattaaa
     1321 ggattgtgcc gtaaggaaat tttatttgct attgatcatt ttaatcagat tgttcgccat
     1381 gagctgctga gaatgatatc atggaaggtc ggcatcgaaa caggctttaa attaagtgta
     1441 ggcaagaact ataagtttat tgaaaggtat atatccgagg atttgtggga gaaacttttg
     1501 tccacctacc ggatggattc ctatgaaaac atatgggaag cattatttct atgccatcaa
     1561 ttgttcaggg cggtatccgg tgaggtggcg gaaaggcttc attatgccta tccggagtat
     1621 gataggaata taacaaaata taccagggac atgtataaaa aatacactgg taaaaccggc
     1681 tgcctggata gcacatatgc cgctgatata gaagagaggc gggaacagtg attacagaaa
     1741 tgaaagcagg gcacctgaaa gatatcgata aacccagcga accatttgag gtgataggta
     1801 agattatacc gaggtatgaa aacgagaatt ggacctttac agaattactc tatgaagcgc
     1861 catatttaaa aagctaccaa gacgaagagg atgaagagga tgaggaggca gattgccttg
     1921 aatatattga caatactgat aagataatat atctttacta ccaagacgat aaatgcgtcg
     1981 gaaaagttaa actgcgaaaa aattggaacc ggtacgctta tatagaagat atcgccgtat
     2041 gtaaggattt cagggggcaa ggcataggca gcgcgcttat caatatatct atagaatggg
     2101 caaagcataa aaacttgcat ggactaatgc ttgaaaccca ggacaataac cttatagctt
     2161 gtaaattcta tcataattgt ggtttcaaaa tcggctccgt cgatactatg ttatacgcca
     2221 actttgaaaa caactttgaa aaagctgttt tctggtattt aaggttttag aatgcaagga
     2281 acagtgaatt ggagttcgtc ttgttataat tagcttcttg gggtatcttt aaatactgta
     2341 gaaaagagga aggaaataat aaatggctaa aatgagaata tcaccggaat tgaaaaaact
     2401 gatcgaaaaa taccgctgcg taaaagatac ggaaggaatg tctcctgcta aggtatataa
     2461 gctggtggga gaaaatgaaa acctatattt aaaaatgacg gacagccggt ataaagggac
     2521 cacctatgat gtggaacggg aaaaggacat gatgctatgg ctggaaggaa agctgcctgt
     2581 tccaaaggtc ctgcactttg aacggcatga tggctggagc aatctgctca tgagtgaggc
     2641 cgatggcgtc ctttgctcgg aagagtatga agatgaacaa agccctgaaa agattatcga
     2701 gctgtatgcg gagtgcatca ggctctttca ctccatcgac atatcggatt gtccctatac
     2761 gaatagctta gacagccgat tagccgaatt ggattactta ctgaataacg atctggccga
     2821 tgtggattgc gaaaactggg aagaagacac tccatttaaa gatccgcgcg agctgtatga
     2881 ttttttaaag acggaaaagc ccgaagagga acttgtcttt tcccacggcg acctgggaga
     2941 cagcaacatc tttgtgaaag atggcaaagt aagtggcttt attgatcttg ggagaagcgg
     3001 cagggcggac aagtggtatg acattgcctt ctgcgtccgg tcgatcaggg aggatatcgg
     3061 ggaagaacag tatgtcgagc tattttttga cttactgggg atcaagcctg attgggagaa
     3121 aataaaatat tatattttac tggatgaatt gttttagtac ctagatttag atgtctaaaa
     3181 agctttaact acaagctttt tagacatcta atcttttctg aagtacatcc gcaactgtcc
     3241 atactctgat gttttatatc ttttctaaaa gttcgctaga tagagttcta tattagagat
     3301 gtaaagagtt ttggtgaaga ggtttgtgag tatggctttt ataaccaggg tgcaatgaga
     3361 agcactaaca gcagctagct taagaacgca taggatatac tttttatgga agtcacagag
     3421 gaggaataaa atttgaacag gattaacaga gtaacctcta ttcttattca gctgcaatca
     3481 aaaaaaataa ttcctgccaa agaaattgca cagcgattta atataagctt aaggacagtt
     3541 tacagagata tccggacact tgaagaagcc ggaataccaa ttggatctga ggccggaaaa
     3601 ggatattttc ttgtagaggg cttcctactt ccgccggtaa tgtttacagc ggcggaagtg
     3661 ggtgcattga ttacagcagg gaaattttta aattgccatg gagatgaatc atttataaag
     3721 gattttgatt cagctatgta taaaatcaaa tctattttga agcatggtga aaaaaactat
     3781 gcacaggagt tggagaacag tattaacgtg tacagcacat ctggacagaa aaatacattg
     3841 gcggataacg ttattgcagc aattcagact gcaatctgca ataaaagggt aatatcaatt
     3901 caatatcctg catcaggagg gcaagaaccg gaaagcagaa tgatagagcc
//
LOCUS       DADQDV010000278         3803 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.guided.159, whole genome shotgun sequence.
ACCESSION   DADQDV010000278 DADQDV010000000
VERSION     DADQDV010000278.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3803)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3803)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3803
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.guided.159"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            62..559
                     /gene="dfrG"
                     /locus_tag="J8S10_003286"
     CDS             62..559
                     /gene="dfrG"
                     /locus_tag="J8S10_003286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HAZ9631778.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(631..2583)
                     /locus_tag="J8S10_003287"
     CDS             complement(631..2583)
                     /locus_tag="J8S10_003287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HAZ9631779.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(2590..2886)
                     /locus_tag="J8S10_003288"
     CDS             complement(2590..2886)
                     /locus_tag="J8S10_003288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631780.1"
                     /translation="MQIGVLKWLQFTKQKGVHFPMQFLEPKNKNAKSVDWEISEQVRV
                     IVKQYAEYAERTESEAVDEFLLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            3228..3518
                     /locus_tag="J8S10_003289"
     CDS             3228..3518
                     /locus_tag="J8S10_003289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAZ9631781.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
BASE COUNT         1184 a          658 c          666 g         1295 t
ORIGIN      
        1 aaggtttttt gatagaaata agaaattaga tggtaaatta gttaaaaagg ctgtgttata
       61 aatgaaagtt tctttgattg ctgcgatgga taagaataga gtgattggca aagagaatga
      121 cattccttgg aggattccca aggactggga atatgttaaa aatactacaa agggacatcc
      181 gataatatta ggtaggaaga accttgaatc aatcggaaga gccttacctg acagaagaaa
      241 tattattctg acgagagata aggggtttac ctttaatggt tgtgaaattg ttcattcaat
      301 agaagatgtt tttgagttat gtaaaaacga agaagaaatt tttattttcg gaggagaaca
      361 gatttataat ttgtttttcc cttatgttga gaaaatgtac atcacaaaaa tacatcatga
      421 attcgaagga gatacttttt ttccagaagt gaattatgag gaatggaatg aggtatttgc
      481 ccaaaaaggg ataaagaatg ataaaaatcc gtataactac tattttcatg tatatgaaag
      541 aaaaaactta ttgagttaac gggtgcgtta attgaagaag aacagtaaag ataaagcaca
      601 agagcttggg attactccaa gctctttttg tcatttgaaa taaattatat ctttccaatc
      661 aaattgttta tctgtaatcc ctaatctttg agcaggtgtc aaaacctttt tatccgctga
      721 tttaaaaggg cgacaaaagt tgtagtaagt tcttagaatt gtaatcgcaa attgagcata
      781 cttcggattg aagttagcgt aaatatagct cttcttatca ccacgagctg ttgttaatgg
      841 tctttcaaga gatgatatat aacgtcttat ctgttgaata aagctattgg tcgaatggtc
      901 attaacattt aatagcatct ttgcgatttc gtttggttcc agagcagata aatccgttct
      961 acaatcaact gaataaaatc ctttatcctt agtggctaat ggatgtttga tagggttatc
     1021 ggcatatttg cgatatcttt ctccatcttt actaatagcc tcttcgtgga attgatgact
     1081 tgttagtaat tcagttagat aatgagatgc caaagtccgt agaaactttg ttttgaatcc
     1141 tctgatatct ccccaatcga gcagttctgc ttttgcttgt ccgaattctt ttaagcattg
     1201 ttttctgctt ttcgtcttgt taacttggca aataaaatga tgtgcatcgc tcaaccttaa
     1261 ttctttcgtg aatactctat aaaaggcgtt tctaatagag aagtcatcat cactaatcat
     1321 tcgccattcg tcggcattaa ccatttgttt aattaaccaa tagtgagcag ttgtagtata
     1381 aggagcatca acatttaaac catcgacaaa tctactccta ttagtaattt tccctaattc
     1441 gtgaagataa gcattcctat tttcgctatc gttagcggat ggttcttgtg gataataaga
     1501 ccaatctaac ctatcatttt tacgactaaa agtattgaga tggtcttctt tgaattttct
     1561 tgtatcttca tttaattcat ccattgaaat attccaatca taggcaacat cagaacggaa
     1621 cacatatctt gataagacct cagcagatac aactatatac gtttgcatat taaggtcttc
     1681 aaaccccgta tatttctttg aaccttgtcc tttcttacgg acgttattta ggtagtagtg
     1741 catcttgtcc gtattaagcc acatctcgtt aaatttcttt gtttgaaggg gttgtgtctc
     1801 atatcgttct aaaaactcca aacaacgcct atacagccac tccagcttat gatagtaggt
     1861 tccaactcca attcctaaaa tatcacaagt acgactgact gaaacccttc caacaaccat
     1921 cttagcgaac attggaagaa tggtgttctt ttgttggtga taagtagtgg tttcttctct
     1981 ttttggtaga acattagtga acttcttaca cgccttacat tgatagcgtt gagatttgcc
     2041 cctacttttc ccccttttgt aaaattgctt cggctcattg aatggggttg attcttcttc
     2101 cgagcagcct tctttatgaa attgataatc tggctcaaca tcttggatgc tattgatttc
     2161 tataaggcgt ttaatttctt caacaacaga ccaattagat aaaggggtta ctgtacagtt
     2221 ttgcgataca cctctgccaa taggattgtc attgcagtac atacctttat gacctttatc
     2281 tttggaacta ccagtcattt tatatcgact tggtttccct tttacatctt tgaatttgtg
     2341 ctgttctttc ccaaaattac aacaaaacgg attgatgcag taattatatt gaatgggata
     2401 ttcagaaccg ttccatttaa aagacgttgg caagaacaac attttgttat accttgttgc
     2461 aaatcgtttt ggagttaata aatcatattg tttagcccta tcttttaatt cttcgtttga
     2521 aatcggaatt ttaacatcta caatttcatc ttccttcgtg gctaatcttt taagcttggt
     2581 cattgtctat caacccactc tatctttgat acccattttt tcaacaatcc gcttattact
     2641 tcgcttgttg gcaatccatt caataaactt cttatcgtct aaaatgttca ataagaattc
     2701 atccactgct tcgctttcag tacgctctgc atattcagcg tattgcttaa ctatcaccct
     2761 tacttgctct gatatttccc aatccacaga cttagcgttc ttattttttg gctcaagaaa
     2821 ttgcatagga aaatgcaccc ctttttgctt agtaaattgt aaccatttta acacaccaat
     2881 ttgcattcct acaataatta tttcacgttc gcatttttat atacatttta acttacattt
     2941 tgtggtgtaa attaacaaca aacgttgatt taacaataaa aaacgagtat caaattcagt
     3001 tgcaatttga tactcattta ggtttacatt ttcacttttt gtactccaaa actgaactac
     3061 ttaaatctat actgctgcct ctttttttta gtacatgtcc ttcatcttcg caggaagtgc
     3121 caatatgatt ttaagaaagg taatagacaa aaagtcaaaa agataaaaca gagtttcttc
     3181 tttacaaagg gaatgtatgt tcgtataatg gtattgaggt gaaggttatg gagaaaaaat
     3241 atggaacagt agataagatc cgtactttgc aagttagtgc cagaccgttg atccgtttca
     3301 gtttaaatgg ggtcaattgt ttgattgctt cccatagttt gaacttccta gctgaagtag
     3361 acgaagggat gaagttagtc gttacaggtt attataataa tagaaagcaa tttgttgtga
     3421 gatcctatca tgtgttaggg aaacccaaaa ttgtggtaga atatgagaaa agtctatacc
     3481 caagaaaaaa ggtccgacaa gatgaaagaa taaactagaa aacaagcggc tgagacaaaa
     3541 atgtcctagc cgcttgtttt ggaaagatgg atgcagacga tgggatttga acccacacga
     3601 gcatacgctc acaagaacct caatctatat ataactacat gtatttaagt atttgtgatg
     3661 aatcactaaa ctttccaaac tcatttgagg gatattgctt aaagattgaa cagatcaatt
     3721 cgaagcccta ttagtattcg ctcaatgggg ggatcagagg ccataaaaag agactagtca
     3781 ttactagtct caggtagtgg aat
//
LOCUS       DADQDV010000279         3025 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.guided.167, whole genome shotgun sequence.
ACCESSION   DADQDV010000279 DADQDV010000000
VERSION     DADQDV010000279.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3025)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3025)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3025
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.guided.167"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            <1..1311
                     /locus_tag="J8S10_003290"
     CDS             <1..1311
                     /locus_tag="J8S10_003290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aminoglycoside N-acetyltransferase
                     AAC(6')-Ie/aminoglycoside O-phosphotransferase
                     APH(2'')-Ia"
                     /protein_id="HAZ9631782.1"
                     /translation="ESLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYH
                     YPKTDEIVYGMDQFIGEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAI
                     RAYQKSGFRIIEDLPEHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVD
                     SIEIIGSGYDSVAYLVNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIE
                     YSYISDELSILGYKEIKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISE
                     CTIDNKQNVLEEYILLRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSC
                     NHLLLDGNNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIE
                     KAKEYQDIVEEYYPIETIVYGIKNIKQEFIENGRKEIYKRTYKD"
     gene            complement(1441..2613)
                     /locus_tag="J8S10_003291"
     CDS             complement(1441..2613)
                     /locus_tag="J8S10_003291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015077585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="HAZ9631783.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTE
                     YIQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKA
                     LMASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKN
                     YPYLMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEY
                     LKERGLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNIFTTIPKKNSKSFRE
                     AVKGIFKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGFEDAFQYTVQGNSHNRL
                     KSTNLIERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
BASE COUNT         1059 a          389 c          538 g         1039 t
ORIGIN      
        1 gaatcattaa aaaaacatta tacagagcct tgggaagatg aagtttttag agtaattatt
       61 gaatataaca atgttcctat tggatatgga caaatatata aaatgtatga tgagttatat
      121 actgattatc attatccaaa aactgatgag atagtctatg gtatggatca atttatagga
      181 gagccaaatt attggagtaa aggaattggt acaagatata ttaaattgat ttttgaattt
      241 ttgaaaaaag aaagaaatgc taatgcagtt attttagacc ctcataaaaa taatccaaga
      301 gcaataaggg cataccaaaa atctggtttt agaattattg aagatttgcc agaacatgaa
      361 ttacacgagg gcaaaaaaga agattgttat ttaatggaat atagatatga tgataatgcc
      421 acaaatgtta aggcaatgaa atatttaatt gagcattact ttgataattt caaagtagat
      481 agtattgaaa taatcggtag tggttatgat agtgtggcat atttagttaa taatgaatac
      541 atttttaaaa caaaatttag tactaataag aaaaaaggtt atgcaaaaga aaaagcaata
      601 tataattttt taaatacaaa tttagaaact aatgtaaaaa ttcctaatat tgaatattcg
      661 tatattagtg atgaattatc tatactaggt tataaagaaa ttaaaggaac ttttttaaca
      721 ccagaaattt attctactat gtcagaagaa gaacaaaatt tgttaaaacg agatattgcc
      781 agttttttaa gacaaatgca cggtttagat tatacagata ttagtgaatg tactattgat
      841 aataaacaaa atgtattaga agagtatata ttgttgcgtg aaactattta taatgattta
      901 actgatatag aaaaagatta tatagaaagt tttatggaaa gactaaatgc aacaacagtt
      961 tttgagggta aaaagtgttt atgccataat gattttagtt gtaatcatct attgttagat
     1021 ggcaataata gattaactgg aataattgat tttggagatt ctggaattat agatgaatat
     1081 tgtgatttta tatacttact tgaagatagt gaagaagaaa taggaacaaa ttttggagaa
     1141 gatatattaa gaatgtatgg aaatatagat attgagaaag caaaagaata tcaagatata
     1201 gttgaagaat attatcctat tgaaactatt gtttatggaa ttaaaaatat taaacaggaa
     1261 tttatcgaaa atggtagaaa agaaatttat aaaaggactt ataaagattg attatataat
     1321 atatgaaaag ctattataaa agacattagt attaaatagt ttaaaaaaat gaaaaataat
     1381 aaaggaagtg agtcaagtcc agactcctgt gtaaaatgct atacaatgtt tttaccattt
     1441 ctacttatca aaattgatgt attttcttga agaataaatc cattcatcat gtaggtccat
     1501 aagaacggct ccaattaagc gattggctga tgtttgattg gggaagatgc gaataatctt
     1561 ttctcttctg cgtacttctt gattcagtcg ttcaattaga ttggtactct ttagtcgatt
     1621 gtgggaattt ccttgtacgg tatattgaaa ggcgtcttcg aatccatcat ccaatgatgc
     1681 gcaagctttt gaatattttg gttgatcgat ataatcatga atcaatcgat ttttagcctc
     1741 acgcgctaag ttaatatctg tgaacttaaa aattccttta acagcttctc tgaaagattt
     1801 tgaatttttt ttaggaatgg tggtaaagat atttcttagg aagtgaactt ggcatctttg
     1861 ccaacttacg ttggtgaagg attttctaat ggcagagact aatcctttgt gcgcatcaga
     1921 aataacgagt tccgtacctt gtaaaccgcg ttcttttagg tattcaaaaa atgttgtcca
     1981 ggtctcttcg ctttcgccac tttgaatcat gaagccgata atttcacggt cgccatcttt
     2041 ggttattcca atcgctatat gacagctttt tgagagtact cgattttctt ctcgtacttt
     2101 tatatagagt acatcggtca ttaagtaagg ataatttttt tctgataata aacgattctg
     2161 ccactcgtta accataggtt ctagctgttc tgttaagcta gaaacgaagg acttagagac
     2221 ggatttacca caaagttctt ccacaatttt tgatacttta cgagttgaaa cgcctgatac
     2281 atacatttcc aacattgaag ccatgagggc tttttcgttt cgttgataac gttcaaacac
     2341 tgtgggtgaa aaatggccat cacgtgttct gggtactttt aattctagcg tgcctacacg
     2401 tgtcgtaaag ctgcgctcat aatagccatt tcgttgactt tgtcggtttt ctgttcgttc
     2461 atattctttt gcttgaatat attctgttcg ttgattttcc attagttgat taaataccgt
     2521 tgttaaaata tttttagaaa cgtcatcctt tacagaatat tcaataatgc tttgaatctc
     2581 ttcgcttttc agtgtaaaat gtacttgggt catgtaaaag tcctcctggg tatgtttttg
     2641 tcgttaaaaa cattgtaccg taaaaggact gttatatggc ctttttactt ttacacaatt
     2701 atacggactt tatctatata aaggcgctgt cagagttttt tgacttagaa catacattca
     2761 ttcaagagac tttaaacaag ctagcagaac gcccaaaaac ggacacacaa ctcgatttgt
     2821 ttagctatga tacaggctga aaataaaacc cgcactatgc cattacattt atatctatga
     2881 tacgtgtttg tttttctgta ctgtttcctg agtgattagc agaaatataa agattaaaat
     2941 tttaattgat tattaggaag agaaggagaa tgtatcccga aaacttttta gttggcttgg
     3001 actgaacgaa gtgagggaaa ggcta
//
LOCUS       DADQDV010000280         2192 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.guided.178, whole genome shotgun sequence.
ACCESSION   DADQDV010000280 DADQDV010000000
VERSION     DADQDV010000280.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2192)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2192)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2192
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.guided.178"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            310..1005
                     /gene="vanR"
                     /locus_tag="J8S10_003292"
     CDS             310..1005
                     /gene="vanR"
                     /locus_tag="J8S10_003292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HAZ9631784.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            983..2137
                     /locus_tag="J8S10_003293"
     CDS             983..2137
                     /locus_tag="J8S10_003293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HAZ9631785.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
BASE COUNT          735 a          405 c          465 g          587 t
ORIGIN      
        1 tatttgatag tagatttaaa actttgcaac agaaccgaaa ttactaatgt atctagggct
       61 tcattataca ggaaattatc agaagtgaat aattagccat tctgtattcc gctaatgggc
      121 aatattttta aagaagaaaa ggaaactata aaatattaac agcctcctag cgatgccgaa
      181 aagccctttg ataaaaaaag aatcatcatc ttaagaaatt cttagtcatt tattatgtaa
      241 atgcttataa attcggccct ataatctgat aaattattaa gggcaaactt atgtgaaagg
      301 gtgataacta tgagcgataa aatacttatt gtggatgatg aacatgaaat tgccgatttg
      361 gttgaattat acttaaaaaa cgagaattat acggttttca aatactatac cgccaaagaa
      421 gcattggaat gtatagacaa gtctgagatt gaccttgcca tattggacat catgcttccc
      481 ggcacaagcg gccttactat ctgtcaaaaa ataagggaca agcacaccta tccgattatc
      541 atgctgaccg ggaaagatac agaggtagat aaaattacag ggttaacaat cggcgcggat
      601 gattatataa cgaagccctt tcgcccactg gagttaattg ctcgggtaaa ggcccagttg
      661 cgccgataca aaaaattcag tggagtaaag gagcagaacg aaaatgttat cgtccactcc
      721 ggccttgtca ttaatgttaa cacccatgag tgttatctga acgagaagca gttatccctt
      781 actcccaccg agttttcaat actgcgaatc ctctgtgaaa acaaggggaa tgtggttagc
      841 tccgagctgc tatttcatga gatatggggc gacgaatatt tcagcaagag caacaacacc
      901 atcaccgtgc atatccggca tttgcgcgaa aaaatgaacg acaccattga taatccgaaa
      961 tatataaaaa cggtatgggg ggttggttat aaaattgaaa aataaaaaaa acgactattc
     1021 caaactagaa cgaaaacttt acatgtatat cgttgcaatt gttgtggtag caattgtatt
     1081 cgtgttgtat attcgttcaa tgatccgagg gaaacttggg gattggatct taagtatttt
     1141 ggaaaacaaa tatgacttaa atcacctgga cgcgatgaaa ttatatcaat attccatacg
     1201 gaacaatata gatatcttta tttatgtggc gattgtcatt agtattctta ttctatgtcg
     1261 cgtcatgctt tcaaaattcg caaaatactt tgacgagata aataccggca ttgatgtact
     1321 tattcagaac gaagataaac aaattgagct ttctgcggaa atggatgtta tggaacaaaa
     1381 gctcaacaca ttaaaacgga ctctggaaaa gcgagagcag gatgcaaagc tggccgaaca
     1441 aagaaaaaat gacgttgtta tgtacttggc gcacgatatt aaaacgcccc ttacatccat
     1501 tatcggttat ttgagcctgc ttgacgaggc tccagacatg ccggtagatc aaaaggcaaa
     1561 gtatgtgcat atcacgttgg acaaagcgta tcgactcgaa cagctaatcg acgagttttt
     1621 tgagattaca cggtataacc tacaaacgat aacgctaaca aaaacgcaca tagacctata
     1681 ctatatgctg gtgcagatga ccgatgaatt ttatcctcag ctttccgcac atggaaaaca
     1741 ggcggttatt cacgcccccg aggatctgac cgtgtccggc gaccctgata aactcgcgag
     1801 agtctttaac aacattttga aaaacgccgc tgcatacagt gaggataaca gcatcattga
     1861 cattaccgcg ggcctctccg gggatgtggt gtcaatcgaa ttcaagaaca ctggaagcat
     1921 cccaaaagat aagctagctg ccatatttga aaagttctat aggctggaca atgctcgttc
     1981 ttccgatacg ggtggcgcgg gacttggatt ggcgattgca aaagaaatta ttgttcagca
     2041 tggagggcag atttacgcgg aaagcaatga taactatacg acgtttaggg tagagcttcc
     2101 agcgatgcca gacttggttg ataaaaggag gtcctaagag atgtatataa ttttggctct
     2161 ttgtcaaatg atgttggtaa agagaaatct ta
//
LOCUS       DADQDV010000281         1418 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.guided.196, whole genome shotgun sequence.
ACCESSION   DADQDV010000281 DADQDV010000000
VERSION     DADQDV010000281.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1418
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.guided.196"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            24..416
                     /locus_tag="J8S10_003294"
     CDS             24..416
                     /locus_tag="J8S10_003294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAZ9631786.1"
                     /translation="MKLLFIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCY
                     TLLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRA
                     CHVYEKLGGKNDYKDEIVYVYDYEKGDK"
     gene            417..>1418
                     /gene="aac(6')-Ie"
                     /locus_tag="J8S10_003295"
     CDS             417..>1418
                     /gene="aac(6')-Ie"
                     /locus_tag="J8S10_003295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012655884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ie"
                     /protein_id="HAZ9631787.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYDGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYL
                     VNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKE
                     IKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYIL
                     "
BASE COUNT          584 a          114 c          235 g          485 t
ORIGIN      
        1 tatagttgaa gaatattatc ctattgaaac tattgtttat tgatgataat atggtttttg
       61 atattgataa tttaaaagga tttcttaatg ataccagttc atttgggttt atagctaaag
      121 aaaataataa aattatagga tttgcatatt gctatacact tttaagacct gatggaaaaa
      181 caatgtttta tttacactca ataggaatgt tacctaacta tcaagacaaa ggttatggtt
      241 caaaattatt atcttttatt aaggaatatt ctaaagagat tggttgttct gaaatgtttt
      301 taataactga taaaggtaat cctagagctt gccatgtata tgaaaaatta ggtggtaaaa
      361 atgattataa agatgaaata gtatatgtat atgattatga aaaaggtgat aaataaatga
      421 atatagttga aaatgaaata tgtataagaa ctttaataga tgatgatttt cctttgatgt
      481 taaaatggtt aactgatgaa agagtattag aattttatga tggtagagat aaaaaatata
      541 cattagaatc attaaaaaaa cattatacag agccttggga agatgaagtt tttagagtaa
      601 ttattgaata taacaatgtt cctattggat atggacaaat atataaaatg tatgatgagt
      661 tatatactga ttatcattat ccaaaaactg atgagatagt ctatggtatg gatcaattta
      721 taggagagcc aaattattgg agtaaaggaa ttggtacaag atatattaaa ttgatttttg
      781 aatttttgaa aaaagaaaga aatgctaatg cagttatttt agaccctcat aaaaataatc
      841 caagagcaat aagggcatac caaaaatctg gttttagaat tattgaagat ttgccagaac
      901 atgaattaca cgagggcaaa aaagaagatt gttatttaat ggaatataga tatgatgata
      961 atgccacaaa tgttaaggca atgaaatatt taattgagca ttactttgat aatttcaaag
     1021 tagatagtat tgaaataatc ggtagtggtt atgatagtgt ggcatattta gttaataatg
     1081 aatacatttt taaaacaaaa tttagtacta ataagaaaaa aggttatgca aaagaaaaag
     1141 caatatataa ttttttaaat acaaatttag aaactaatgt aaaaattcct aatattgaat
     1201 attcgtatat tagtgatgaa ttatctatac taggttataa agaaattaaa ggaacttttt
     1261 taacaccaga aatttattct actatgtcag aagaagaaca aaatttgtta aaacgagata
     1321 ttgccagttt tttaagacaa atgcacggtt tagattatac agatattagt gaatgtacta
     1381 ttgataataa acaaaatgta ttagaagagt atatattg
//
LOCUS       DADQDV010000282         1073 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.guided.212, whole genome shotgun sequence.
ACCESSION   DADQDV010000282 DADQDV010000000
VERSION     DADQDV010000282.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1073
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.guided.212"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            111..194
                     /locus_tag="J8S10_003296"
     CDS             111..194
                     /locus_tag="J8S10_003296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HAZ9631788.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            319..1056
                     /gene="erm(B)"
                     /locus_tag="J8S10_003297"
     CDS             319..1056
                     /gene="erm(B)"
                     /locus_tag="J8S10_003297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004292767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HAZ9631789.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
BASE COUNT          403 a          174 c          166 g          330 t
ORIGIN      
        1 ccttatttga tagtagattt aaaactttgc aacagaacca ttttgtgtat aataggaatt
       61 gaagttaaat tagatgctaa aaatttgtaa ttaagaagga gggattcgtc atgttggtat
      121 tccaaatgcg taatgtagat aaaacatcta ctgttttgaa acagactaaa aacagtgatt
      181 acgcagataa ataaatacgt tagattaatt cctaccagtg actaatctta tgacttttta
      241 aacagataac taaaattaca aacaaatcgt ttaacttctg tatttattta cagatgtaat
      301 aacttcagga gtgattacat gaacaaaaat ataaaatatt ctcaaaactt tttaacgagt
      361 gaaaaagtac tcaaccaaat aataaaacaa ttgaatttaa aagaaaccga taccgtttac
      421 gaaattggaa caggtaaagg gcatttaacg acgaaactgg ctaaaataag taaacaggta
      481 acgtctattg aattagacag tcatctattc aacttatcgt cagaaaaatt aaaactgaac
      541 attcgtgtca ctttaattca ccaagatatt ctacagtttc aattccctaa caaacagagg
      601 tataaaattg ttgggagtat tccttaccat ttaagcacac aaattattaa aaaagtggtt
      661 tttgaaagcc atgcgtctga catctatctg attgttgaag aaggattcta caagcgtacc
      721 ttggatattc accgaacact agggttgctc ttgcacactc aagtctcgat tcagcaattg
      781 cttaagctgc cagcggaatg ctttcatcct aaaccaaaag taaacagtgt cttaataaaa
      841 cttacccgcc ataccacaga tgttccagat aaatattgga agctatatac gtactttgtt
      901 tcaaaatggg tcaatcgaga atatcgtcaa ctgtttacta aaaatcagtt tcatcaagca
      961 atgaaacacg ccaaagtaaa caatttaagt accgttactt atgagcaagt attgtctatt
     1021 tttaatagtt atctattatt taacgggagg aaataattct atgagtcgct ttt
//
LOCUS       DADQDV010000283          899 bp    DNA     linear   BCT 03-APR-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate V2439
            SAMN18324362-rid11863703.guided.230, whole genome shotgun sequence.
ACCESSION   DADQDV010000283 DADQDV010000000
VERSION     DADQDV010000283.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN18324362
            Sequence Read Archive: SRR13984660
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 899)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 899)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-APR-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-APR-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000996740.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000996740.1
            Genome Coverage       :: 83x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/02/2021 07:19:29
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 3,298
            CDSs (total)                      :: 3,237
            Genes (coding)                    :: 3,170
            CDSs (with protein)               :: 3,170
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2 (16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 30 of 67
            Pseudo Genes (incomplete)         :: 35 of 67
            Pseudo Genes (internal stop)      :: 10 of 67
            Pseudo Genes (multiple problems)  :: 7 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..899
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN18324362-rid11863703.guided.230"
                     /isolate="V2439"
                     /isolation_source="rectal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2018-02-13"
                     /collected_by="Hospital, Capital Region, Denmark"
     gene            286..834
                     /gene="aac(6')"
                     /locus_tag="J8S10_003298"
     CDS             286..834
                     /gene="aac(6')"
                     /locus_tag="J8S10_003298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HAZ9631790.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT          321 a          129 c          187 g          262 t
ORIGIN      
        1 gattattata tgaaaacagg ttttatttgt caattcataa ttggtttttt ttaaagcaaa
       61 agataatcta tatcatgatg aacaaacaga gttttttcct ccaattgatg gctttcctga
      121 tctttcctat tttgaataaa gtgtttctgt ataatttttt attttataag taagataaat
      181 aatgaaagaa tagagatact gattggtagc taaagatttt tgagcgagaa catttcgttt
      241 tttcaaaagg actgttagaa taagcaagaa caagggggaa gacgtatgat aatcagtgaa
      301 tttgaccgta ataatccagt attgaaagat cagctttctg atttactgag actgacttgg
      361 ccggaagaat atggagacag ctcggcagaa gaagtagaag aaatgatgaa tccagaacga
      421 atcgcggtag cagcggtaga ccaagatgag ttagtaggat ttattggtgc aatccctcaa
      481 tacggtatca caggttggga attgcatcca ttagttgtag aaagctcccg acgaaagaac
      541 caaataggta ctcgattagt caattactta gaaaaagaag tagcttccag aggaggaatc
      601 acgatttatt taggtacgga tgatttagac catggaacaa cgttaagtca aacggacctg
      661 tatgagcata catttgataa agtggcttcc atccagaacc ttcgtgaaca tccgtatgaa
      721 ttctatgaaa aattaggtta taaaatcgta ggtgtcttac caaatgcaaa tggctgggac
      781 aaaccggata tttggatggc aaaaacgatt attcctcgac caaattctca ataataaaaa
      841 gaggttgtga cagaagtaat cagcttcaag aaataagaag gaatttacga aaattactt
//
